LOCUS       DAIGSZ010000001       100364 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.001, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000001 DAIGSZ010000000
VERSION     DAIGSZ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 100364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.001"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            352..1041
                     /locus_tag="NOB31_000001"
     CDS             352..1041
                     /locus_tag="NOB31_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0972252.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1028..2236
                     /locus_tag="NOB31_000002"
     CDS             1028..2236
                     /locus_tag="NOB31_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0972253.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2530..3801
                     /gene="serS"
                     /locus_tag="NOB31_000003"
     CDS             2530..3801
                     /gene="serS"
                     /locus_tag="NOB31_000003"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HCI0972254.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="NOB31_000004"
     CDS             complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="NOB31_000004"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HCI0972255.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6339..7034)
                     /locus_tag="NOB31_000005"
     CDS             complement(6339..7034)
                     /locus_tag="NOB31_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HCI0972256.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="NOB31_000006"
     CDS             complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="NOB31_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HCI0972257.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8233..8424)
                     /locus_tag="NOB31_000007"
     CDS             complement(8233..8424)
                     /locus_tag="NOB31_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HCI0972258.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8445..9335)
                     /locus_tag="NOB31_000008"
     CDS             complement(8445..9335)
                     /locus_tag="NOB31_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HCI0972259.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9322..10089)
                     /locus_tag="NOB31_000009"
     CDS             complement(9322..10089)
                     /locus_tag="NOB31_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI0972260.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="NOB31_000010"
     CDS             complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="NOB31_000010"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HCI0972261.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="NOB31_000011"
     CDS             complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="NOB31_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HCI0972262.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="NOB31_000012"
     CDS             complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="NOB31_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HCI0972263.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14660..15043
                     /locus_tag="NOB31_000013"
     CDS             14660..15043
                     /locus_tag="NOB31_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972264.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15211..15969)
                     /locus_tag="NOB31_000014"
     CDS             complement(15211..15969)
                     /locus_tag="NOB31_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HCI0972265.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(15987..16805)
                     /locus_tag="NOB31_000015"
     CDS             complement(15987..16805)
                     /locus_tag="NOB31_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCI0972266.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="NOB31_000016"
     CDS             complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="NOB31_000016"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HCI0972267.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="NOB31_000017"
     CDS             complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="NOB31_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HCI0972268.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            17934..19268
                     /gene="dnaA"
                     /locus_tag="NOB31_000018"
     CDS             17934..19268
                     /gene="dnaA"
                     /locus_tag="NOB31_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HCI0972269.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19466..20596
                     /gene="dnaN"
                     /locus_tag="NOB31_000019"
     CDS             19466..20596
                     /gene="dnaN"
                     /locus_tag="NOB31_000019"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HCI0972270.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            20825..21067
                     /gene="yaaA"
                     /locus_tag="NOB31_000020"
     CDS             20825..21067
                     /gene="yaaA"
                     /locus_tag="NOB31_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HCI0972271.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21054..22178
                     /gene="recF"
                     /locus_tag="NOB31_000021"
     CDS             21054..22178
                     /gene="recF"
                     /locus_tag="NOB31_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HCI0972272.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22175..24121
                     /gene="gyrB"
                     /locus_tag="NOB31_000022"
     CDS             22175..24121
                     /gene="gyrB"
                     /locus_tag="NOB31_000022"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HCI0972273.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24141..26612
                     /gene="gyrA"
                     /locus_tag="NOB31_000023"
     CDS             24141..26612
                     /gene="gyrA"
                     /locus_tag="NOB31_000023"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HCI0972274.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            26848..27147
                     /locus_tag="NOB31_000024"
     CDS             26848..27147
                     /locus_tag="NOB31_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HCI0972275.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27197..27709
                     /gene="ssb"
                     /locus_tag="NOB31_000025"
     CDS             27197..27709
                     /gene="ssb"
                     /locus_tag="NOB31_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCI0972276.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27735..27971
                     /locus_tag="NOB31_000026"
     CDS             27735..27971
                     /locus_tag="NOB31_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HCI0972277.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28114..30087
                     /locus_tag="NOB31_000027"
     CDS             28114..30087
                     /locus_tag="NOB31_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HCI0972278.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30093..30545
                     /gene="rplI"
                     /locus_tag="NOB31_000028"
     CDS             30093..30545
                     /gene="rplI"
                     /locus_tag="NOB31_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HCI0972279.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            30819..32186
                     /gene="dnaB"
                     /locus_tag="NOB31_000029"
     CDS             30819..32186
                     /gene="dnaB"
                     /locus_tag="NOB31_000029"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCI0972280.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            32966..34258
                     /locus_tag="NOB31_000030"
     CDS             32966..34258
                     /locus_tag="NOB31_000030"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HCI0972281.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35045..35908
                     /locus_tag="NOB31_000031"
     CDS             35045..35908
                     /locus_tag="NOB31_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI0972282.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36037..37659)
                     /locus_tag="NOB31_000032"
     CDS             complement(36037..37659)
                     /locus_tag="NOB31_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0972283.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            37908..38429
                     /locus_tag="NOB31_000033"
     CDS             37908..38429
                     /locus_tag="NOB31_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCI0972284.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38615..40345)
                     /gene="spxB"
                     /locus_tag="NOB31_000034"
     CDS             complement(38615..40345)
                     /gene="spxB"
                     /locus_tag="NOB31_000034"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HCI0972285.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40510..41328
                     /locus_tag="NOB31_000035"
     CDS             40510..41328
                     /locus_tag="NOB31_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HCI0972286.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41431..41628)
                     /locus_tag="NOB31_000036"
     CDS             complement(41431..41628)
                     /locus_tag="NOB31_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972287.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41797..42375
                     /locus_tag="NOB31_000037"
     CDS             41797..42375
                     /locus_tag="NOB31_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCI0972288.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42470..42607
                     /locus_tag="NOB31_000038"
     CDS             42470..42607
                     /locus_tag="NOB31_000038"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972289.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43420..43923)
                     /locus_tag="NOB31_000039"
     CDS             complement(43420..43923)
                     /locus_tag="NOB31_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCI0972290.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44282..45307
                     /locus_tag="NOB31_000040"
     CDS             44282..45307
                     /locus_tag="NOB31_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0972291.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45630..46508
                     /locus_tag="NOB31_000041"
     CDS             45630..46508
                     /locus_tag="NOB31_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HCI0972292.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLADEHIGSGLGILTS"
     gene            46984..47100
                     /locus_tag="NOB31_000042"
     CDS             46984..47100
                     /locus_tag="NOB31_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HCI0972293.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48028..48366
                     /locus_tag="NOB31_000043"
     CDS             48028..48366
                     /locus_tag="NOB31_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972294.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48460..48690
                     /locus_tag="NOB31_000044"
     CDS             48460..48690
                     /locus_tag="NOB31_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972295.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49090..49461
                     /locus_tag="NOB31_000045"
     CDS             49090..49461
                     /locus_tag="NOB31_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HCI0972296.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49735..50427)
                     /locus_tag="NOB31_000046"
     CDS             complement(49735..50427)
                     /locus_tag="NOB31_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0972297.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50430..51215)
                     /locus_tag="NOB31_000047"
     CDS             complement(50430..51215)
                     /locus_tag="NOB31_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0972298.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51452..52852
                     /gene="lacG"
                     /locus_tag="NOB31_000048"
     CDS             51452..52852
                     /gene="lacG"
                     /locus_tag="NOB31_000048"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCI0972299.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            52877..53194
                     /locus_tag="NOB31_000049"
     CDS             52877..53194
                     /locus_tag="NOB31_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0972300.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53207..54880
                     /locus_tag="NOB31_000050"
     CDS             53207..54880
                     /locus_tag="NOB31_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HCI0972301.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            54894..56525
                     /locus_tag="NOB31_000051"
     CDS             54894..56525
                     /locus_tag="NOB31_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HCI0972302.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(57016..58581)
                     /gene="guaA"
                     /locus_tag="NOB31_000052"
     CDS             complement(57016..58581)
                     /gene="guaA"
                     /locus_tag="NOB31_000052"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCI0972303.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(58640..59563)
                     /locus_tag="NOB31_000053"
     CDS             complement(58640..59563)
                     /locus_tag="NOB31_000053"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCI0972304.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            59759..60364
                     /locus_tag="NOB31_000054"
     CDS             59759..60364
                     /locus_tag="NOB31_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0972305.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            60672..61688
                     /locus_tag="NOB31_000055"
     CDS             60672..61688
                     /locus_tag="NOB31_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI0972306.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            61829..63130
                     /locus_tag="NOB31_000056"
     CDS             61829..63130
                     /locus_tag="NOB31_000056"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HCI0972307.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            63176..63838
                     /gene="deoC"
                     /locus_tag="NOB31_000057"
     CDS             63176..63838
                     /gene="deoC"
                     /locus_tag="NOB31_000057"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCI0972308.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            63859..64257
                     /locus_tag="NOB31_000058"
     CDS             63859..64257
                     /locus_tag="NOB31_000058"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCI0972309.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            64323..65405
                     /locus_tag="NOB31_000059"
     CDS             64323..65405
                     /locus_tag="NOB31_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0972310.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            65617..67179
                     /locus_tag="NOB31_000060"
     CDS             65617..67179
                     /locus_tag="NOB31_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0972311.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            67172..68305
                     /locus_tag="NOB31_000061"
     CDS             67172..68305
                     /locus_tag="NOB31_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0972312.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            68305..69261
                     /locus_tag="NOB31_000062"
     CDS             68305..69261
                     /locus_tag="NOB31_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0972313.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            69360..70526
                     /gene="deoB"
                     /locus_tag="NOB31_000063"
     CDS             69360..70526
                     /gene="deoB"
                     /locus_tag="NOB31_000063"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCI0972314.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            70550..71368
                     /locus_tag="NOB31_000064"
     CDS             70550..71368
                     /locus_tag="NOB31_000064"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI0972315.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            71385..72092
                     /gene="deoD"
                     /locus_tag="NOB31_000065"
     CDS             71385..72092
                     /gene="deoD"
                     /locus_tag="NOB31_000065"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCI0972316.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(72390..73076)
                     /gene="gpmA"
                     /locus_tag="NOB31_000066"
     CDS             complement(72390..73076)
                     /gene="gpmA"
                     /locus_tag="NOB31_000066"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCI0972317.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(73248..73829)
                     /locus_tag="NOB31_000067"
     CDS             complement(73248..73829)
                     /locus_tag="NOB31_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0972318.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(73962..74645)
                     /gene="rpiA"
                     /locus_tag="NOB31_000068"
     CDS             complement(73962..74645)
                     /gene="rpiA"
                     /locus_tag="NOB31_000068"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HCI0972319.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            74964..75377
                     /gene="rpsL"
                     /locus_tag="NOB31_000069"
     CDS             74964..75377
                     /gene="rpsL"
                     /locus_tag="NOB31_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HCI0972320.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            75461..75931
                     /gene="rpsG"
                     /locus_tag="NOB31_000070"
     CDS             75461..75931
                     /gene="rpsG"
                     /locus_tag="NOB31_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HCI0972321.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            76025..78112
                     /gene="fusA"
                     /locus_tag="NOB31_000071"
     CDS             76025..78112
                     /gene="fusA"
                     /locus_tag="NOB31_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCI0972322.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            78284..79471
                     /gene="tuf"
                     /locus_tag="NOB31_000072"
     CDS             78284..79471
                     /gene="tuf"
                     /locus_tag="NOB31_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCI0972323.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            79878..80186
                     /gene="rpsJ"
                     /locus_tag="NOB31_000073"
     CDS             79878..80186
                     /gene="rpsJ"
                     /locus_tag="NOB31_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HCI0972324.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            80217..80846
                     /gene="rplC"
                     /locus_tag="NOB31_000074"
     CDS             80217..80846
                     /gene="rplC"
                     /locus_tag="NOB31_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HCI0972325.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            80874..81497
                     /gene="rplD"
                     /locus_tag="NOB31_000075"
     CDS             80874..81497
                     /gene="rplD"
                     /locus_tag="NOB31_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HCI0972326.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            81497..81787
                     /gene="rplW"
                     /locus_tag="NOB31_000076"
     CDS             81497..81787
                     /gene="rplW"
                     /locus_tag="NOB31_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HCI0972327.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            81826..82659
                     /gene="rplB"
                     /locus_tag="NOB31_000077"
     CDS             81826..82659
                     /gene="rplB"
                     /locus_tag="NOB31_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HCI0972328.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            82702..82980
                     /gene="rpsS"
                     /locus_tag="NOB31_000078"
     CDS             82702..82980
                     /gene="rpsS"
                     /locus_tag="NOB31_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HCI0972329.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            83003..83350
                     /gene="rplV"
                     /locus_tag="NOB31_000079"
     CDS             83003..83350
                     /gene="rplV"
                     /locus_tag="NOB31_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HCI0972330.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            83364..84020
                     /gene="rpsC"
                     /locus_tag="NOB31_000080"
     CDS             83364..84020
                     /gene="rpsC"
                     /locus_tag="NOB31_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HCI0972331.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            84023..84457
                     /gene="rplP"
                     /locus_tag="NOB31_000081"
     CDS             84023..84457
                     /gene="rplP"
                     /locus_tag="NOB31_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HCI0972332.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            84447..84635
                     /gene="rpmC"
                     /locus_tag="NOB31_000082"
     CDS             84447..84635
                     /gene="rpmC"
                     /locus_tag="NOB31_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HCI0972333.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            84660..84926
                     /gene="rpsQ"
                     /locus_tag="NOB31_000083"
     CDS             84660..84926
                     /gene="rpsQ"
                     /locus_tag="NOB31_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HCI0972334.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            84984..85352
                     /gene="rplN"
                     /locus_tag="NOB31_000084"
     CDS             84984..85352
                     /gene="rplN"
                     /locus_tag="NOB31_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HCI0972335.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            85389..85697
                     /gene="rplX"
                     /locus_tag="NOB31_000085"
     CDS             85389..85697
                     /gene="rplX"
                     /locus_tag="NOB31_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HCI0972336.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            85725..86264
                     /gene="rplE"
                     /locus_tag="NOB31_000086"
     CDS             85725..86264
                     /gene="rplE"
                     /locus_tag="NOB31_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HCI0972337.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            86283..86468
                     /locus_tag="NOB31_000087"
     CDS             86283..86468
                     /locus_tag="NOB31_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HCI0972338.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            86504..86902
                     /gene="rpsH"
                     /locus_tag="NOB31_000088"
     CDS             86504..86902
                     /gene="rpsH"
                     /locus_tag="NOB31_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HCI0972339.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            86934..87470
                     /gene="rplF"
                     /locus_tag="NOB31_000089"
     CDS             86934..87470
                     /gene="rplF"
                     /locus_tag="NOB31_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HCI0972340.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            87631..87987
                     /gene="rplR"
                     /locus_tag="NOB31_000090"
     CDS             87631..87987
                     /gene="rplR"
                     /locus_tag="NOB31_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HCI0972341.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            88008..88508
                     /gene="rpsE"
                     /locus_tag="NOB31_000091"
     CDS             88008..88508
                     /gene="rpsE"
                     /locus_tag="NOB31_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HCI0972342.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            88523..88702
                     /gene="rpmD"
                     /locus_tag="NOB31_000092"
     CDS             88523..88702
                     /gene="rpmD"
                     /locus_tag="NOB31_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HCI0972343.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            88746..89186
                     /gene="rplO"
                     /locus_tag="NOB31_000093"
     CDS             88746..89186
                     /gene="rplO"
                     /locus_tag="NOB31_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HCI0972344.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            89186..90481
                     /gene="secY"
                     /locus_tag="NOB31_000094"
     CDS             89186..90481
                     /gene="secY"
                     /locus_tag="NOB31_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HCI0972345.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            90543..91190
                     /locus_tag="NOB31_000095"
     CDS             90543..91190
                     /locus_tag="NOB31_000095"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HCI0972346.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            91381..91599
                     /gene="infA"
                     /locus_tag="NOB31_000096"
     CDS             91381..91599
                     /gene="infA"
                     /locus_tag="NOB31_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HCI0972347.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            91632..91748
                     /gene="rpmJ"
                     /locus_tag="NOB31_000097"
     CDS             91632..91748
                     /gene="rpmJ"
                     /locus_tag="NOB31_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HCI0972348.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            91766..92131
                     /gene="rpsM"
                     /locus_tag="NOB31_000098"
     CDS             91766..92131
                     /gene="rpsM"
                     /locus_tag="NOB31_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HCI0972349.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            92159..92548
                     /gene="rpsK"
                     /locus_tag="NOB31_000099"
     CDS             92159..92548
                     /gene="rpsK"
                     /locus_tag="NOB31_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HCI0972350.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            92628..93566
                     /locus_tag="NOB31_000100"
     CDS             92628..93566
                     /locus_tag="NOB31_000100"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HCI0972351.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            93594..93974
                     /gene="rplQ"
                     /locus_tag="NOB31_000101"
     CDS             93594..93974
                     /gene="rplQ"
                     /locus_tag="NOB31_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HCI0972352.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            94246..95085
                     /locus_tag="NOB31_000102"
     CDS             94246..95085
                     /locus_tag="NOB31_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0972353.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            95061..95930
                     /locus_tag="NOB31_000103"
     CDS             95061..95930
                     /locus_tag="NOB31_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0972354.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            95920..96717
                     /locus_tag="NOB31_000104"
     CDS             95920..96717
                     /locus_tag="NOB31_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCI0972355.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYCVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            96920..97666
                     /gene="truA"
                     /locus_tag="NOB31_000105"
     CDS             96920..97666
                     /gene="truA"
                     /locus_tag="NOB31_000105"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCI0972356.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            98331..98568
                     /locus_tag="NOB31_000106"
                     /pseudo
     CDS             98331..98568
                     /locus_tag="NOB31_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(98712..99488)
                     /locus_tag="NOB31_000107"
     CDS             complement(98712..99488)
                     /locus_tag="NOB31_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI0972357.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            99611..100018
                     /locus_tag="NOB31_000108"
     CDS             99611..100018
                     /locus_tag="NOB31_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HCI0972358.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        31464 a        18447 c        20702 g        29751 t
ORIGIN      
        1 tttccaacat gtcaacaact tattttttat tatttaataa gttattggtg ttcttttgaa
       61 caaataataa tatatcaaca tcacatgtga aagtcaataa gaaaatgctt atttatcaac
      121 atttctagct tacatgatca ttggttagtt ctggtccttt ttcgttcgtc tttataactc
      181 cgagagacgt aaaatccttt tgttttcagt ttaatgttca tgttcttgtc ttattcacac
      241 caactagatg tctcaccttc taaaattttc cttaacaaag tgctgctttt atctatttct
      301 gctttttttt gctagaataa tagtaacaat atgactctgg aggatttatt tatgaaaatt
      361 ttgattgctg acgatgataa agaaatcgtt gaattattaa gtatctatgt tcacaatgag
      421 gggtatgaag cagtaaaggc ttatgatggg aaagaagcat tatctaaaat cagaacaatc
      481 cctgatattg aattacttat tttagatatc atgatgcctg agatggatgg gatgcaagta
      541 gtgaaagagc tacgaaaaga atcccaaata ccaatcatta tgctgacagc aaaaactact
      601 gatatggata agatcaaagg actggtcgct ggtgcagatg attatgtgac caagccattt
      661 aatccgttag aagtaatggc tagagtaaag tctttattac ggcgtacaaa aatgcagatt
      721 gccccagatc agcctgatgt attagaagta aatgcattaa tcatcaataa agactctcat
      781 gaagttaaaa caatcgatgg gaaagaaatc cagttaacag ctttggaatt cggtatcctc
      841 tacttgcttg ctagtcatcc taatcgagta tttagcgcgg atgaaatttt tgagcgtgtt
      901 tggaaacaag aaagtattgt ctctgctaaa actgtcatgg ttcacgttag tcatttaaga
      961 gataagattg aagaagcaac tggtggtgaa aaagtcattc aaaccgtttg gggagtgggc
     1021 tataaaattg acgcaagata gtaaacgagc aactgaaaaa cgccgtcgga tcaatttgac
     1081 ttcaaaagaa atcagcgaat tgttagcgga aggaatcatc acgattatcc ttttgcttct
     1141 attaaatgtt tctattctgg ttgttatcag ttcggtgatc aacagttcac cttctttgac
     1201 gaatgcgatt tgggattcaa agaatatttt tgcagaacga ttgaacactg atttgttctg
     1261 gaacggccgg aattttatta ttcccttttt ctttctatta gatattggtg ttttgtattg
     1321 gcgcttgatt cgaagatatc gccaaatgca attgcggcat atcatcagcg aacttcacta
     1381 catcgcaaac ggaaattatg atcatcgtat cccttttgaa ctgagtggtg acttaagccg
     1441 agtggtaaca agtatcaatg gattggtgga tagtaccgta gcagcgattg aagacgaacg
     1501 taaaatcgaa aaatcaaaag atgaattgat cacgaatgtc agtcatgata tccgtacccc
     1561 actcacgtcc atcattggat acctaggact gatagaagat ggccagtatc actcagaaga
     1621 agatctttta aagtatacgc atactgctta tatcaaagca aagcagatga aatctttagt
     1681 ggacgactta tttgaataca ctaaggtacg ccagcctgct gtcccggtga atttttctgc
     1741 ctttgacatg atccagttga tcgaacagtt agcagctgat tttgagttgg aagcttctaa
     1801 aaaaaatatc caaatacttg ttcaatcaaa agtagactcc cttatcatgg atggcgatac
     1861 cgaaaaactt gtacgtgtct tcaataatct tttgacgaat gcgttgaaat acggaaaagg
     1921 agcaacgaag atcgtaatcg aagtagaacg tatcggttca gaagttgttg caacagtcaa
     1981 aaataacgga gcaatgatcc cacaacaggc aatcgataat ctattcgacc gtttttatcg
     2041 tgtagaagaa tctcgttcac aagcaactgg aggaactgga cttggtttag caatcgctca
     2101 aagcattgtg gctttgcacg gcggatacat ttatgcaaaa tcagataagc aatggacttc
     2161 tttcatcatg caccttccaa tcaagaaaaa tgaaaaatta cctattgata cacaggaagt
     2221 tattgacgaa agctgaaata ttcgctattc ttattacaat tattagaata aatgaaaaac
     2281 acagaaccca gtacacttta ttctttttca gagagctgat ggcaggtgta aatcagcaaa
     2341 ggataatttg gaagttccag ttcgtttacg tgccctttcg aaataagaaa ggtcggttca
     2401 acagccgtta tgtgttcaac aagtgcagct gacgctgaac ttgggtggta ccgcgaattt
     2461 cagactgatt cgtcccaaga ataatgggat ggatcagtct ttttttattt tcaaaaagga
     2521 ggaaatcata tgttagatgt aaaaatgatg cgacaaaata ttgaagaagt acaagaaaaa
     2581 ttgatgactc ggggcgtaaa aaaagaaaca ttagctgaat tcatggaact agatgaaaat
     2641 cgtcgtaagc tactagtcaa aagtgaagaa ttaaaaaaat atcgaaatga tgtttctgct
     2701 gagatcgccc aattgaagcg tgcaaaagaa gatgcttctg ctaaaatcgc tgaaatgaaa
     2761 gaagtcggtg gcaacatcaa agcattggat actgaaattg ctgaagtgga tgaaaaattg
     2821 aaacaaattg caactacttt gccaaacctt ccccatgatt ctgtgccagt tggaacagat
     2881 gaagaggaca atgtagaaat ccgtcgttgg agcgaaccac gtacatttgc ttttgaacca
     2941 aaaccacact gggaaattgc agaaaatctt gatattttag attttgaacg tggcgcaaaa
     3001 gtagccggta gccgttttgt ctattacaaa ggattaggtg ctcgattaga acgtgctgtc
     3061 tacaacttca tgcttgatca gcatatttac gaacacggct atactgaaat gatcactcct
     3121 tatatcgtca acagtaaagc gatgtttggt acgggacaat ttccaaaatt caaagaagat
     3181 gttttccaat tggagaatac tgatctaaca ttaatcccaa cagctgaagt accattaact
     3241 aactattata atgatgaaat tttagatggt gcagatttac ctatttattt cactgcacta
     3301 agccctgctt ttcgttctga agccggaagt gctggtcggg atacacgagg actgattcgt
     3361 cttcaccaat tcaataaagt agaaatggtc aaattttcgg atgtagagca ttcttacgaa
     3421 gaattggaaa aaatgacagc tgatgcagaa gatatcttga aaaaattgca tttgccttat
     3481 cgtgtgatgg ccttatcaac tggagacatg ggcttttctg cagctaaaac ttatgactta
     3541 gaagtatgga tacctgcaca agatacttat cgtgaaatca gttcttgttc taactgtgaa
     3601 gatttccaag cacgccgcgc aatgatccgt tatcgcgata atgatggaaa aatccactat
     3661 actcatactc tgaatggttc aggacttgca gttggccgta cagtagctgc cattttggaa
     3721 aactaccaaa atgaagatgg ttctgtcaca gttccagaag cgctcgttcc ttatatgggg
     3781 aatctgaaag ttattaaata aagaggctgt gaaaaagccg cttagtttcg agtattaaga
     3841 aaaattttgt gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac
     3901 tggcttttga acaccattta tcgagaggtt gtgaaatcag cgaattaacc tgagtattag
     3961 agaaaaaaat ggaaaaatag tccctcatat tttaccgttt gttgaactaa taccgagggt
     4021 cagctgattg aacaccgttt agtggagagg tcgtaagcct accccccagc tcctagttac
     4081 aaggacaaat tcaaaaaaca gctcttcata ttttatgaat gttgtacttg tgattcggag
     4141 gtggcaaggg aacactgttt attcaaaaag aggctgggac agaagcgttt aactccaaga
     4201 aataagaaga aattcacgaa aattgctttt caaatttttg tgaatttctt cttatttccg
     4261 aaggagttgc ttctacttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct
     4321 ttacttttgt cccacgctct ttaatgtttt taagattcaa ctgaatagtt tggtgcttct
     4381 tttgtgattt gtacatcatg agggtgtgat tcttttaatc cactgccgct catttggata
     4441 aattgcgctt catcacgtaa ttgctgtaga ttggctgccc caacataacc cattcctgaa
     4501 cgcaaaccgc cgatcatttg gaaaataata tctgcaacac ttcctttata agcaacccga
     4561 ccttcgattc cttctggtac taatttattt gcttcattga cactaccttg gaagtaacgg
     4621 tcttttgaac ctttttccat cgcgcctaat gagcccatac ctcggtatgt tttgaatcga
     4681 cgtccttgga agatttcgaa ttcacctggt gattcatctg tccctgccaa catacttcct
     4741 agcatcactg catgtccgcc ggcagctaat gctttgacga tgtcaccaga atatttgatc
     4801 cctccgtctg caataatcgc tttgccatat tgacgagcaa ctgatgctgc atcataaata
     4861 gctgtgagct gaggtacacc tacaccggct accacacgtg tcgtacaaat cgatcctggt
     4921 ccgataccaa cttttacgac atctacacct gcatcatata aagcttttgt cgcttcagcc
     4981 gtcgcaacgt ttcctgcaat caatgttgca tctgcaaaag ttgaacggat ttcttgaatt
     5041 tttcggatca cacctgcact atgtccatga gctgtatcga tgatgattgc atctgcccct
     5101 gcttctaata aagcattcgc acgctcaaat gtatcgcttg ttacaccaac ggctgctgct
     5161 acaagcaatc gaccatgttc atcttttgct gcatttggaa attcgatcac tttctcgatg
     5221 tctttgatcg tgatcaatcc gcttaaacga ccttcgttat ctacgattgg taatttttcg
     5281 attttatgtt tttgcaaaat cttttctgca tcttttagag aggtacctac tggggcagtc
     5341 actaagttgt cttttgtcat cacatcagca atcggcatgt gataatctgt tacaaaacgc
     5401 atgtcgcggt ttgtaattat ccctaccaat tttctgtttt caagtgtttc aacgattggc
     5461 acaccactga tacgatattt gctcatcaat tcttctgcgt ctgctacaag atgctgcggc
     5521 gttaagaaga acggatcaat gattacgcca ctttcagaac gtttgacttt tcttacttca
     5581 tccgcttgct ggctgatcgt catgttttta tggatcacac ctagtccgcc ttgtcttgcc
     5641 atagcaatgg ccatcttgct gtcggtaaca gtatccatac ttgcactgat gattggaata
     5701 ttcaacttaa tatttttagc taattgtacg ctcatatcca cttcgtttgg taacacgtga
     5761 ctttctgctg gtatcaataa gacatcatca aaagtaaatc cttttttcgt gaactttgtt
     5821 tcccagttgg acatttttag taccactcct ctaatttagt ttatctatta aaataattga
     5881 ttttttcatt taagtcaatg atctacttgg aatcaagtta gctttctcat agaataccaa
     5941 tataaagcgt ttacatctgt gtgtattaaa agagattgta aaaaagctgt cctgcatcaa
     6001 gtaataagaa cagccaatca aaaacagctt ctcatgtttt tgaattggtt gggtttatta
     6061 ccgcagatgc aaacttttga acaccgttta gtggagaggc tgtgaaaaag ctgcttagtt
     6121 tcgagtagta agaaaaattt tgtgaaaatg gctttccaca tttttgcata aattggactt
     6181 aataccgaga aactggcttt tgaacaccgt ttatcgtaaa aagggactgt gacaagactt
     6241 ttgtcacagt cccttactat tatttaacta tggataaaca aaatgaggtt ctttactacc
     6301 cctagatatc tagcaaaata gctgatcttt ttgctagttt atcttcttgg gacggataaa
     6361 cttccaataa tcccgtattt tttcttcaag tagtaacgga ttgctaaagc agttgccccg
     6421 ataatgataa ctactactgg atctaatact ggattgataa ctggtggcaa tagtgttgtc
     6481 gcagaaaaca gtacgaccca aagaagtgtc gttccaccta ggataagcaa tgtcttaccc
     6541 attcctggtt tcttgcttcg atctgctccg ggatattcat attgatagat gtatttgtac
     6601 atcatataaa agacccagcc accgattgca gaacctagaa cgagtgtaga aaagccataa
     6661 gctggcgttg ttccacgtga aaacaatccg gtaatcgcaa tcatgatact taatagacca
     6721 agcaacagca acgtattatc taaccacatc aataaagggg tggatgaatt ttttacttct
     6781 gctggcttat tgatgattgc ttccgttctt tcagagactg tcccaaacaa ttgacgggct
     6841 gttcttccgc ctttttgttc tgcaactaaa gtaggcagaa tgtcatgaag ggcttttact
     6901 ttttcttctt cagacaaatt cgctgcttct aaagattttt tcaaatcaaa aatgtactgt
     6961 tgatttcttt tggttaattt tgtttctaaa ctattgtttt cttttacgat tgctcgtaat
     7021 tgttctggtt ccattatcta atagtcctcc ttagccgttc cttttctcaa cggtcgtcac
     7081 aaaagacatt ctaccatatt ctacagctag tttgatagcc cttttacaca ttaaagcgga
     7141 ataacattac gtcgccgtct tgtacgacat aatcttttcc ttctaatcga acacgtccag
     7201 cttcttttgc tgcatgcatg tttccgtaat gatccaagtc ttcaaaagag acagtttctg
     7261 cacggataaa tccgcgttcg aaatctgaat ggatgattcc tgctgcttgt ggtgctttga
     7321 ttcctttttt gaatgtccaa gcacgtactt cttgttcccc agcagtaaag taagtagcta
     7381 agcctaacaa atcataagca gcacggatca actgatccaa acctgattct tcgattccta
     7441 aagcttctaa aaattccgct ttgtcttctt catctaattc tgcgatttct tcttctgcac
     7501 gagcactgac cacgatcact tctgcatttt cttctgcagc aaagttgcgc acttcttgta
     7561 cataatgatt cgcgtctgca tctgctacgt catcttctga gacattggct acataaagaa
     7621 ttggttttgt cgtcaataaa aatagtgatt taacgatttt ttgttcttct tcagtaaatt
     7681 cgatcgttcg ggcagatttt ccttcttcca gtacaggttt gattttatcc agtacagcta
     7741 gttctgccac tgcatcttta tctttggttt tagcaacttt tgctacacga gtatagcgtt
     7801 tgttgataga ttctaagtct gctaacacta gttccaagtt gatcgtatca atatcttcta
     7861 gtggatcaac acgtccttct acgtgagtaa tattatcatc atcaaaacag cgaacaacgt
     7921 gacaaatagc gtctacttgg cggatatggc ttaagaattg atttcccaaa ccttctcctt
     7981 tacttgcgcc ttttacgatt ccagcaatat ctgtaaattc aaaagtcgtc ggaacagttt
     8041 ttttcggatg tacaagttct gttaagcgtt gcaaacgcca gtcaggtact tctaccatcc
     8101 ctacgttggg gtcgatcgtc gcaaagggat agtttgctgc ttctgctcct gcttttgtga
     8161 tcgcattaaa caaagttgat tttcctacgt tgggcaaccc aacaattcca gcagtcaatg
     8221 ccataaattt attcactctt tctctgcatt tttttcaatt acttttttta atttcttttc
     8281 aaaatctcga cgggtcatca tgacgatatg tccgcaattc atacatctga ttttgatatc
     8341 tgcgcccatt cgaatgactt cccagcgatt cgtctggcaa gcgtgaggtt ttttcatttc
     8401 aacgatatcg tgcaagtcgt acataaaaat agcctccttt ttgtttattc ttcatcaaat
     8461 tgaatattca agatatcaag aattcgagtc aaatcttttt gagaaagata ttcaatctcg
     8521 atcttacctt tcccattttt ttcttggata gctacacttg taccaaattt atccatcaaa
     8581 cgatcttcgc tttctcggat ataatatggt ttttcctttg ctagccttgg gatttttttc
     8641 ttttcttttc catcattttg atttaactca gaaacaagct gttccagttg gcggacagtt
     8701 aaattttcag ttactgcacg attggctaat ttcaagatca atgttttatt ttttaaacct
     8761 aacagcgtac gggcttgtcc catagataaa cgctgatctt gtaccatttc cttgacaaga
     8821 tccggtaaag aaagcaagcg caaataattg gcgatataag gtctgctctt tcctaaacga
     8881 ctagctactt ctgcttgtgt tagtttcagg tttttcatca gcatctcata tgcttctgct
     8941 tcttctaacg gattcagatc ttctcgctgc aagttttcca gcactgctac ttgcatcatc
     9001 gcttcttcgt caaagtctct aacgatagca gggatcgttt ctttttcagc tagtttggac
     9061 gctcgaaaac gtcgctcccc tgcaataatc tcatatcctt ttactgcgga acggcgtacg
     9121 atgatgggtt gaaagacacc tgattgttca atagaattag ctagttcctg caaagatact
     9181 tcttcaaatg ttttacgggg ctgatacgga tttggtcgca gctcattcaa tggtagctgg
     9241 acaacggtat catcttttac atccaccgtc tctaagtttt ctaaatcttg aaacagtgca
     9301 tcgattcctc ggcctaatcc tttacttttc ttcacgactt accacttcct ttgccaatgc
     9361 ttggtagact tcagctcctc gagaacgtgg atcgtagtcg atgatcggtt ttccatgact
     9421 aggtgcttct gataaacgaa tatttcttgg aatgatcgtt tcgtaaactt tttcgcggaa
     9481 gtatttacgt acttcttcta cgacttcatt tcccagattt gttcgtgcat catacattgt
     9541 cagtaagact ccctcgatct ctaattctgg attaaagtgt ttttggacta aacgaaccgt
     9601 attcagtaat tggcttaatc cttccaatgc gtaatactca cactgaacag gtatcaaaat
     9661 cgaatcactt gctgtaaatg aattgattgt cagatggcca agagaaggcg ggcaatcgat
     9721 caaaatataa tcatactgac tgcttacttc tgctaaagat ccttttaatc ttgattctct
     9781 tgccatcatt gacgtcaatt cgatctctgc tcctgctaat tggagagtcg caggcacaat
     9841 actcaaattt tcgtgttcag tgatcaaagt tgcctcatca attggcaatt cattgactag
     9901 aacatcatag atgtctcttg tcacatcagg ttttctgatc ccgacaccac tggtagcatt
     9961 tccttgtgca tccatatcca ctagcaatac ttttttgcca aggctagcaa gacaagcacc
    10021 tagattcacc gtcgtcgttg ttttgccgac gccacctttt tggttcgcaa cagatattat
    10081 ttgtgccatc tcttctcctc ctatttgatt ggctgcttat taggcagtcc gggctttctt
    10141 gggtatttct ttggggttgg tttctttttt tgaataacga tgatatgccg ttgatcagag
    10201 acattcggca aggtaaccgc ctcttctttg aggaatttac cacctaataa agcaatcgct
    10261 tgttttgctt ctgtcaattc ctcttcactt tttgctgctt tcaatgcata aaaatagcct
    10321 tcttgtttag ccaagggcaa acacaattcc gctaacacat tcaaacgagc aaccgcacga
    10381 gcagtgacaa ggtcaaatga tgcacgaaag tgaggatttt gcccaaatgt ttctgcccgg
    10441 tcatgatata aggaagcatc gattcctaat aatcgggtta actcagataa gaaggttatt
    10501 cgtttattca gagaatcaac gatcgttatc tgcagttctg gaaaggcaat ttttaaaggt
    10561 atgctaggaa accctgcccc cgaaccaaca tcgcataaag ataaaggttg cgtaaagtct
    10621 acttcaaatg ctaatgtaag tgaatcgtaa aaatgcttca gatatacgtc tttttcatcc
    10681 gtaatagctg taaggttcat cttttcgttc cattcgacta atgtccgata ataaatagcg
    10741 aattgattca tttgatgatc ggtaagctct atcccttttt ctgccaagga ttggcgaaat
    10801 tcttctggta tcataaatat tcctttcatt gtgaaacagc aattgtttca cagattctct
    10861 ccctacttta acgcaaaatc tctagacatg caatccttcc atatggattc ttaaaaattt
    10921 gaaaagtaag aaaagccgat agactttttc tttctagtat gactcataaa atatacacag
    10981 aagagagaac tagctttgag caatttctgc aaaaactagt tctctcttct atttattatt
    11041 acgtattacg ctggttcact gactttcgca atcttccctt gttcgatata gaccattagg
    11101 atacttaggt ctgcagggtt tacgccactg attcggctag cttgggcaat tgtttctggt
    11161 tggattttct gcaatttttg ttttgcttct gttgctaatc cgttgattgc tgcgtagtcg
    11221 atgttttctg gaatcttttt cgcttccatg cgttttaatt tttctacttt ttccatggct
    11281 tttttgatgt agccttcata tttgatttgg atttctactt gttcgatttc ttttcgtgtc
    11341 aattcttcat tttctggaat aaaccgtaga agttctgcat aagtaatctc aggacgtctt
    11401 aaaaagtcgc ttgctagtac accatctttt aatggtgccg cattaatcgt tgctaaaaag
    11461 tcttggactt cttctgttgg tttgattcgt acattcatca aacgtttgat ttcttgttca
    11521 actgcttctt ttttcttcaa ataattcttg tattgatctt cttttactaa gcctacacgg
    11581 tgacccattt ctgttaatcg caaatctgca ttatcatgac gtaaaagcag acggtattca
    11641 gcacgtgaag tcagcaaacg ataaggttcg ttcgttcctt ttgttaccaa atcatcgatc
    11701 atgacaccga tgtaaccgtc acttcgtttg atcactaaag gttcttttcc ctgaactttc
    11761 aaagctgcat tgataccggc aatcagccct tgtccagccg cttcttcata accgcttgta
    11821 ccatttgttt gtccagctgt ataaagattt tcaacgactt tagtttctaa tgtcggacgg
    11881 agctggtgtg gctctactac gtcatattcg atagcatatc ctgtacgcat catttctact
    11941 ttttctaatc cagcaataga atgaagcatg ttgacttgaa catcctctgg taaagaagta
    12001 gataaacctt gaacatagac ttcttccgta tttaagcctt ctggttccaa aaataattga
    12061 tgacgtggtt tgtctgcaaa acgcacgatc ttatcttcga tggatggaca atagcgagcg
    12121 cctacccctt caacgatccc tgtaaacatt ggggcacgat gtaagttgtc tcgaataatt
    12181 tggtgagtcg tctcacctgt ataggtcagc cagcaagatt cctgatctag tttataggca
    12241 ctatctggtg tgctgaagct aaaatgattc ggctctttgt caccaggctg ctcttctgta
    12301 acagaatagt cgatcgtact tgattttact cgaggcggtg ttcctgtttt gaaccgttcg
    12361 atagcaaagc caagttcttt tagatgattc gctagtccaa tagaaggttg agagttattc
    12421 ggacctgatg aatatttcaa ttcaccgata atgatttctc cgcgaagtgc tgttccggct
    12481 gtaataacaa ctgctttggc ccggtagctc gctcctgtgg acgtcactac tccatgacaa
    12541 acaccatctt cgacgatcag ttcttcgacg attccttgtc ttagcgtcaa atttggttct
    12601 ttttcgatcg tatgtttcat ttctgttgaa taagcatgtt tgtctgcttg tgctcgcaat
    12661 gctcggacag ctgggccttt tcctgtgttc aacatacgca tttggatata ggttttatcg
    12721 atattcttac ccatttctcc gcctaacgca tcgatttctc gaacgacaac gcctttagct
    12781 ggtccgccta cagaaggatt acatggcatg aatgctacca tgtccaaatt tattgtcagt
    12841 aataatgttt ttgatcccat acgtgcagca gcaagtgcag cttctgaacc ggcgtgtcct
    12901 gcgccaacaa cgatcacgtc atacgcatct gcttcataat gttccaatcg tttgttcctc
    12961 cttttatttt cctaaacaaa attgactgaa taattgagtg attagctcat cttgtacact
    13021 gtcgccgaca acttctccta gatagtccca gcaacgcgtc atatctattt gaacgagatc
    13081 cacaggcatt cctgaatcaa tacctgcaat gacttcttca agtgagaggg aagctttttc
    13141 taacaacgcg atatggcggg tattagaaac ataagtagcg tctctttctc ctgtttctcc
    13201 gctgaagaat aaatcagaaa tagctgattc caaacgatct agtccgtcgt ttttagctac
    13261 ggaaattgaa aaaactggtt cattttcgat caatttcttc aatttttctt gttccagctg
    13321 tgctggcaaa tctgttttat ttagaagaat gatccgtttc aatccacttg tcgcttccaa
    13381 taattgttca tcttctgctg tcagtggttc gctttggttt agaacaagta agatcaagtc
    13441 tgcttctgct aatgcttttc ggcttctttc gaccccgatc cgttccacca catcttctgt
    13501 ttcccgaatt ccagctgtat cgattagctt gagcggtacc ccccgaacat tgacatactc
    13561 ttcgattaca tctcgagtcg ttcctgcaat atccgtaacg attgcttttt cttctcttaa
    13621 caaatggttt aacaaacttg atttgccgac atttggccgg ccgatgattg ccgtacttaa
    13681 cccttcccgc agaaccttcc cttgcttgga tgtagcaagt agcgcttgga ttctttgttg
    13741 gatcatctgc gctttttcaa gcaataactt cgtagtcaat tcttcgacat catcatattc
    13801 tggataatca atatttactt ctacttgtgc taatgtctct aaaatctctt gtctcaatga
    13861 gcggatcaaa gcagacagat tgccgtctaa ctgattaaga gctagtccca ttgctttgtc
    13921 tgtttttgcc cgaatcaaat ccatcacagc ttctgcctgt gaaaggtcaa cacgaccatt
    13981 caagaatgct cgttttgtga attcgcctgg ctcagctaat cttgcacctt ctcttaacaa
    14041 tagctgcaaa atttgattga ctacaacgat cccaccgtga caattgattt ctactacatc
    14101 ttcccgcgta aatgtctttg gtgctctcat cacggagacc atgacttcat cgacaagctg
    14161 attgctcttg ggatcaacga tatgtccata atggatcgta tgacttggta cttctgataa
    14221 tcgtttgttt ccagattgat aaactttatc tgctagttgc acagcttgat cgccacttaa
    14281 acgaacgata ctgattgcac cttctccagg tggggtagaa attgccgcaa tcgtatcaaa
    14341 ttctaaagta atttcagcca ttttttcact tcctttttca ttttgcgcac aaaaaaagtg
    14401 cccactccac cctttatgca caataaacgg tgaacttcgc actttgactg cttgttcttg
    14461 attaaattct ggtcatagat tatcacactt gctataagga atcaagtgtt taaaacaatt
    14521 agatgaagtt gagcctgttc tgcttccatt accttatatt taattgtcct tggatgtctc
    14581 tttgcgttct ttggtttatt cgaagagaag atactgtata aacaaggctt tatctttctt
    14641 aaaaaaaacg gtacactaaa tggtagcgct atctaaacta tacacttttg aaaggagaaa
    14701 atatgtgagc ccgttcagat ctgctgcatt ggaagaagaa agtgaccctc ggatcaacga
    14761 tgtcgtttta tctacaggga atatcaacca gaaatatatc gtccgcgata tcgtttttgt
    14821 tgtggaatgc ttagaagctg atttgtttga cccatctttt cccaaagatg accttttctt
    14881 aacaacgaag aggaaattaa agacgaaggt acttgaatat ggtgcgaatg cagtaatcaa
    14941 ctgtcatttt gagtatcagc aaaaaaaacg cgacggaaag tattttctgg aactttttgc
    15001 ttatggaaca gtgatccaat ttatccaaac aacgattggt taaatgaaac agacaaaaaa
    15061 agcggatcaa aactgaagac agtttcgatc cgcttttttc tatcaaagtt agtgactact
    15121 tcatcgtata ctctgataag aatgatttct agtaaaatat acttggtttg aaaaactttg
    15181 tcaacgtgat ttattcaaaa agtaatggaa tcaataatat tttttagcag gttctactac
    15241 taaataacga taaggttcct caccttccga atgtgttttt acatgttcat ctttgcttaa
    15301 tgcagcatgg atttgtttac gttcaaatgc aggcattggt tctaagaaaa caggctgccc
    15361 tgtccgtttt actttttcag ccgtgcgatc agctaaacgc tgaatgatct cttggcgctt
    15421 ttcacggtaa ttgcctacat tgactactac agacagctta tttcttgcta aacgatggat
    15481 gaagacttgt gccagatatt gcaatgcatt cagtgttttt ccatgtttcc caatcagtat
    15541 gccttgcttt tgtgtttcta aatggaaaac aaccatatta tttgattctc tttccatttt
    15601 gacaagagct ggagcatcaa gctgttttga aatttcagta agataaactg ccaattccgt
    15661 taaagctgct tcatcaccta gctcacttac ttcttctgtt ttttcttcaa gaatcgtttc
    15721 gttgactacc tcgatctcag ctgttggttc ttcttccaaa atttcttcta cagtctgttc
    15781 tactgtttca gaaacttttt cgctgatact tggctggatc gaaagccgtg cattctttcg
    15841 acccattcct aggaaacctt tttttccttc ttccagtatt tcgatttcga cttggtcttt
    15901 ggccaaaccc aaatcagcca gacctagttg gacagcttcg tctattgttg cagcttcata
    15961 aatcggcatt agcattacct cccctattat ttccgttttt tcttaggatt cattgctttc
    16021 ttaagagcac gttctctttc gcggattctc cgtgcttctt cttcacgctc ttttcgaatt
    16081 ttgaaagggt tgttgatcag cagcgtttgt acaacttgga aggcattgga aactacccag
    16141 tataatgaaa gaccgctggc taaattgaca cccatcacta aaatcattac aggcatcacg
    16201 aaattcatga tcttcattga tgcattcgat tcaatttgac tcatgctaga taaatacgta
    16261 cttgcaaaag taaagattgc tgctaaaatc ggcaaaataa atgttggatc cgcgttccct
    16321 aagttcaacc ataagaaatg cccttgtttc aactctggta cacgtgaaat agattgccat
    16381 aacgccatca agattggcat ttgtactaat aaaggaagac aaccagcata tggattgacg
    16441 ccattttctg catataaacg ctgctgctct tctcttaact tactttgtgt ttccggatct
    16501 cttgaactat attgttgctg cagtgctttt aatttcggtt gtaattcttg cgttttacgc
    16561 atgctctttg tttggaaatg catcaacggc aataggatca cgcggatgat cagtgtaaat
    16621 aaaatgatcc ctatccctgc attaccaaat gacaacgcct tgatcgcctc agcaaagtaa
    16681 taaacaatat aacgatccca aattcctgta ctctgtgcgc tgacttcccc agttccgcaa
    16741 ccggataaga cgatgaccaa actaacgata ccggccatca aaagtaaacg tttgtatttc
    16801 ttcacttact cttttcctct ctgtcgatta tttttgcaag ttttaagacg tggactaaat
    16861 tggagcgaac ctcatcataa gtcaacccct tcacacttgg tctagcaatc acaataaaat
    16921 ccaactccgg atcaatttct tcttttatag aataaactgc tgctcggatt tttcgtttga
    16981 cttcattgcg gtttaccgcg ttgccgacct tttttcctac agataaacca actcgaaaat
    17041 gaggctgtcc cggtttttcc aaacggtaaa cgacgaattt gcggttagca aaagaatctc
    17101 ccgtatggaa cacggcttga aactctcgtt ctttttttac tcgatacgct tttctcatta
    17161 gttttctttc cttttctatc tctcacttac gctcataatc ataccataat tacgattgtc
    17221 ctttcatcat ttccctaaaa aagagtataa aaaaaaccac tgaaacccca gtggcctaag
    17281 ctgaaagaac ttttcttcct ttgcgacgac ggctagctaa cacacgacgt ccatttttag
    17341 tactcatacg tttacggaat ccgtgaactt tttgacgttt acgtttattt ggttggtatg
    17401 ttcttttcat atattccacc tccaaaatgt tcttatctat tttataaaca cagacatact
    17461 ttgatagtat aacgacaaag tagtgatttt gtcaatataa aatagaagat cgattgttaa
    17521 aacttatcca caagattatt tttttctatg ggagtcctat gtggaaaaag ttatgcacag
    17581 ggattatcca cagataataa atggctggtt ttacacagaa aacacacgtg taaaaaaagt
    17641 aatccacaat caggtgattt cctgtgtatt ccgtctccta actattggta tatctatatt
    17701 ttttatccac agatgcaaga ggaaatctat tgatttttac gagttttcca cctgtgcatt
    17761 agtggtgtgg aaaacttttt tttgacaact gtgtttttct cttttttctt tttgtcgatt
    17821 gtgtggataa ttgtaattaa aaaatttttt tcttcggttt ctgtggaaaa ctattgaaaa
    17881 aaatgctaaa ttagtactag ttattcactt tttaatgaag gaggaggcct tatatggtat
    17941 ccctcgatgc tttatggaat gaattaaaag caacatacca aaaggattta tcgcctgcta
    18001 gctataatac atggatcgaa acagcgaacc ctcgaaccct tgatcaaaac cagctcgttg
    18061 ttgaggttcc tagcaagatt cataaagaat attgggaaaa aaacctggcg acaaaaatcg
    18121 ttgaagtcgg ttatatgtta tcaggaaatg agattatccc tcgctttatt actggcgaag
    18181 aagcagagca agaagaagtt atagaagaaa aaaatccaaa agttgtggca cctagtccgc
    18241 taaaaaaagc catgctgaac cctaaatata cctttgatac gtttgtcatt ggtaaaggaa
    18301 accagatggc tcatgcagca gcgctcgttg tagcagaaga tccaggttct atttataacc
    18361 cgctcttctt ttatggaggc gtgggacttg gtaagactca cttgatgcat gcaattggtc
    18421 atcaaatgct gcaaagtcag cctaatgcca aagtaaaata tgtaagcagt gaaacttttg
    18481 ctaatgattt catcaattcg atccaaaaca aaacagcaga agagttccgt caagaatatc
    18541 gaaatgttga tttactgcta gtggatgaca ttcaattttt tgcagaaaaa gaagctacgc
    18601 aagaagagtt tttccatact ttcaatgcct tgtacaatga agggaaacaa atcgtactaa
    18661 ccagtgatcg gttgccaaac gagattccga aactgcaaga acgcctcgtt tctcgctttg
    18721 catgggggct gtctgttgat attacaccgc cggatcttga aacaagaaca gcgattttac
    18781 gtaaaaaagc ggcggctgaa cgtctagaga tcccagatga cacactaagc tacatcgcag
    18841 gacaaattga ttctaacatt cgtgaattag aaggtgcgct tgttcgagtg caagcttttg
    18901 ctgcgatgaa tagtgaagat atttcgacta gtctagctgc agacgcactg aaaacgttaa
    18961 aatcaggaaa aggacatcct caattgtcaa tcctgcagat ccaagaagaa gtggcaaagt
    19021 attatcacat ccaattgaaa gatatcaaag gaaagaaacg cgtcaaatct attgttgttc
    19081 ctagacaaat cgctatgtat ttggcacgtg agctcacaga taattcttta ccgaaaatcg
    19141 gagctgaatt cggtggcaag gatcatacaa cggttatcca tgctcatgaa aaaatccagc
    19201 agctgatgga ttctagtgtc agtatgcaaa atgaagtatc agaaatcaaa aactttttac
    19261 taaattaatt tgtcgattct atcaactgaa aatagcatgt ggataaaaga aaaaaacgtt
    19321 caaaagttat gcacactttt tccacagctg ttttttcgtt tctctcttac gttttttgag
    19381 ttttccacag aatcaacatg ccctattact tttattattc tttttaacta ataataaata
    19441 aacaaacatt caaaggagat acatcatgaa agttacttta aaccgagcta gctttatgca
    19501 ggaattgcaa actgttcaac gagctatttc aagcaaaacc acgatcccta ttttgacagg
    19561 tgtaaaaatc acactgacac aagaaggttt gactttgacg gggagcaacg ctgatatatc
    19621 aattgaaact tttttgtctg ttgaaaacga aaaagcaaat atgcaaatcg aatctactgg
    19681 ttccattgtt ttacaagcac gtttctttag cgaaatcatt cggagacttc ctgaagaaac
    19741 atttacttta gaagttttag aaaataaaca agtagcgatt acttctggaa aagcgaattt
    19801 tatcgtaaat ggattagatg cagataacta tcctcatctt cctgttgtcg aaagccataa
    19861 ccagatgaaa ttacctgtac acgtattgac taaactaatc aacgaaacag tttttgctgt
    19921 ctcacaacat gagagtcgtc caatcttgac aggtgtgcat ttcattttat ctgataattc
    19981 tttattggct gtagctactg attctcaccg tctaagtcaa cgcgtgattc cagtagaaca
    20041 agcggctgat cattttgata ttgttattcc tggaaaaagt ttgatcgaat tatctcgctc
    20101 attaacaaat gaagaagaaa tcgtcgaaat cagcattatg gaaaaccaag tgttgttcaa
    20161 aacagaaacg atgtatttct attcccgttt gctagaagga aactatcctg ataccaatcg
    20221 tttgattcct tcaagtttta atacagaggt tgaattttct gttcctagct ttttagcggc
    20281 gatcgaacgg gcttctttac tttctcatga aggccgtaac aacatcgttc gtttatctat
    20341 tcgtccagat gcggttgttt tatacggaaa ttcgccagaa atcgggaaag tagaagaaag
    20401 cttgagttat acagcaagca gtggcgatcc attagatatt tctttcaatc cggattatat
    20461 gaaagcagcg ttgcgtgcat ttggagatat gagcatcaaa gtgaaattta tctctgctat
    20521 tcgtccattt acattggaac caacggaaga tggcgttcaa tttattcagc tgattactcc
    20581 tgtacgtaca aattaacaat gattttcatt gttcttgaaa atttaattga aaagaaatag
    20641 aaaaaataaa attttaaaca gaaggcccta aaatctcttt taaggctttc tgtttatttt
    20701 tgtttaaatc acctttttta gattaaatcg tcttatatgg aaaaatatat ggataaattt
    20761 gttttattgc gaaaaaaaag gtataataga gtatactttt aataatgaaa atgagggatg
    20821 ggcattgaaa caacaagtca ttctaaatac ggaattcatg acgttgggcc aaatgttgaa
    20881 agaagtcaca gttatcggta gtggcggaca agcaaaatgg tatttggcag aaaacactgt
    20941 gttagtcgat ggcgaaccag aaaatcgtcg tggacgcaaa ctttatcccg gcatgatggt
    21001 tgaagttcca gaagtaggaa ctttttttat ggtaaaaaaa ggaaacgacg ataatgaggc
    21061 tgaataagct gtatttaaaa aattatcgaa attacgaaga gctgaacatc gaattttcca
    21121 agaacctcgt catcttttta ggagaaaatg cgcaaggaaa aacgaatctt ttggaaagta
    21181 tctacgtatt agctatgacg cgaagtcatc ggacaagtag tgagcaggaa ttgattggct
    21241 ggactgacga tcaggcgatg attcaaggag agatcacaaa aggttcatcc actcttccat
    21301 tagaaatctt attatctaaa aaaggccgaa aaaccaagat caaccatatc gaacaaaaaa
    21361 agttaagtac ttacgtggga caaatgaatg tcattttatt tgcaccagaa gatctttctt
    21421 tagtaaaagg cagcccgcag atcaggcgga agtttttaga tatggaatta ggccagatca
    21481 atccaatcta tctttatgat cttgtccaat accaagcaat tttgaaacaa agaaaccagt
    21541 atttaaagca attgaatgaa aaaaaacaaa ctgatttgct ttatttggat attttgtccg
    21601 aacaactagc agcgtttggc agcaaagtat tgaaagcaag agcacagttc gtcaagcgat
    21661 tggagttttg ggctaattct ttgcatcagc aaatcaccca tcaaaaagag cagctggaaa
    21721 tcgagtatct caccgcagtc gattctttag aaacacatac gcaagagcaa atccaagaac
    21781 aatttctcgc acttttgaac caaaataaaa agaaagacct ttttcgggga acaacgacag
    21841 ttggtcctca tcgtgacgat ctttcctttt ttattaatca gaaaaatgtg cagacttatg
    21901 gatcgcaagg acagcaaaga acaactgcac taagtgtcaa attagcagaa atcgatttga
    21961 ttaaagaaga gacgggggaa tatccaatcc ttttgttaga tgatgtgatg agcgagctgg
    22021 atgatagtcg tcaactccat ctgctagaaa caatcgaagg aaaagttcaa acgttcttaa
    22081 caacaacgac acttgaccat gtaaaaaata aaatgactgt tgaacctgag attttttatg
    22141 ttcaacaagg gaaactaaaa ggagaagaaa ctgaatgaca gaagaaagaa gtttagtaga
    22201 acgcgctaaa gagtatgatg ccagtcagat tcaagtactt gaaggacttg aagccgttcg
    22261 taaacgacct ggcatgtata tcggttcgac tagttctgag ggtctgcatc accttgtttg
    22321 ggaaattgtc gataattcga tcgatgaagt attagcaggt tttgcaacga aaatccatgt
    22381 gattattgaa aaagacaaca gtatcaccgt tattgacgac ggtcggggga tacctgtaga
    22441 tatccaggca aaaactggac gtcctgcagt tgaaacggtc tttactgttt tacatgctgg
    22501 aggaaaattc ggcggtggtg ggtacaaagt ttctggtgga cttcacggag taggatcttc
    22561 tgttgttaac gcgctttcta cacagcttga tgtcaaagta tacaaagaag gaaatgtgta
    22621 ctatcaagaa tatcgtcgtg gagctgtagt ggacgactta aagattatcg aacaaacgga
    22681 tcgccatgga acaacggttc actttacgcc agaccctgaa atttttacag agacaactga
    22741 gtttgatttt tcaaaattgg ctacccggat ccgtgaactt gctttcttga accgcgggat
    22801 gcgtatatcg attgaagaca aacgagaaga agaaccagtc atcaatgaat accattatga
    22861 cggcgggatt aaaagttatg tcgaatactt gaatgcaaac aaaaccgtga tttttccaga
    22921 acctgtatat ttggaaggtg aacagcaaga tatcgcagtt gaagtctcta tgcaatatac
    22981 agacggctac cattccaata tcatgagttt tgccaacaat atccatacgt atgaaggcgg
    23041 aacacatgaa tcaggattca agactgcttt aactcgtgtg ataaatgatt atgcccgaaa
    23101 acaaaagctg atgaaagaaa atgacgacaa cttgaccggt gaagacgtgc gagaaggatt
    23161 gacagctgtt atttctatca agcatcctga ccctcaattc gaaggacaaa caaaaacaaa
    23221 attgggcaat tccgaagtac ggacagtcac tgatcggtta tttagcgaac atttcatgaa
    23281 attcttgctg gaaaacccaa gtgtgggccg tcaaattgtt gaaaaaggat tactagcttc
    23341 cagagctcgt ctagcagcga aacgtgcgcg tgaagtaacg agacgtaaag gtgctttaga
    23401 gattagtaat ctgccaggaa aattagcgga ctgctctagc aacgatcctg aaaaatgcga
    23461 attgttcatc gtcgaaggag attcggccgg cggatcagct aagcaaggtc gtaatcgaga
    23521 gtttcaagcc atcttgccta ttcgtgggaa aatcttgaat gttgaaaaag caagcatgga
    23581 caagatcttg gcaaatgaag agatccggtc tttatttact gctatgggta cagggtttgg
    23641 agaagatttt gatgtatcga aagctcgcta ccacaaatta gttatcatga ctgatgccga
    23701 tgtcgacggc gcgcatatcc gtacattgct gctgactctt ttttatcgtt acatgcgtcc
    23761 tattgttgaa gctggatacg tctatattgc tcagccacct ttatacgggg taaaacaagg
    23821 gaagaatatt acgtatgtac aaccaggaaa aaatgcagaa gaagagttga aacaagtcgt
    23881 tgcttcactt cctgcctcac caaaaccaag cgttcagcgt tataaaggac ttggagaaat
    23941 ggatgatcat caactatggg aaacaactat ggacccaagc aatcggatga tggcccgcgt
    24001 cagtgtggac gatgctattg cagcagatca gatatttgaa atgttgatgg gggatcgagt
    24061 agaaccccgt cgtgcattca tcgaggaaaa tgcacactat gtgaagaact tagatattta
    24121 atcatgaagg aggaaaaaga atgagtgaag aaatcagaga aaacatccat gatgtcaatc
    24181 taaccagcga aatgaaagac tccttcatcg attatgcgat gagtgttatt gtcgcacgtg
    24241 cacttcctga tgtcagagat ggtctgaaac ccgttcatcg ccgtatttta tacggcatga
    24301 acgaattagg tgtaacaccg gataaagccc ataaaaaatc tgccagaatc gtcggagatg
    24361 tcatgggtaa ataccatcct catggagact atgcgatcta tgagtcaatg gtacggatgg
    24421 cacagccatt cagctaccgt tatatgctag tggatggtca tggaaacttt ggttctgttg
    24481 acggtgacgg tgccgccgct atgcgttata ccgaagcacg gatgagcaaa atcgctacag
    24541 aaatgctgcg tgatatcaat aagaacactg ttgatttcca aagcaactat gatgatacag
    24601 aaaaagaacc agttgtacta cctgctcgct tcccgaatct tttagtgaac ggaacaacgg
    24661 ggatcgccgt aggtatggcc acgaatatcc cacctcataa cttgtctgag gtagtagcgg
    24721 ctatcgattt gctgatggat aatcctgatg tgacgaccaa tgaattgatg gaagtattac
    24781 ctggaccaga ttttccaaca ggtggtttgg ttatgggaaa atcaggaatc cgaagagcgt
    24841 atgaaacagg taagggttct attaccgtac gtgcaaaagt tgagattact gagatgccaa
    24901 atggtaaaga acggatcatc gtgacagaat tgccttatat ggtcaataaa gcaaaattga
    24961 tcgaacggat ttctgaactg cacagagaca agcgtatcga agggatcaca gatttgcggg
    25021 acgaatcttc ccgtgaaggt atgcggatcg tcattgacat ccgtcgtgac gccagcgcat
    25081 ctgttatctt gaataactta tataaattga catccttgca aaattcattt ggattcaata
    25141 tgttggcgat cgaaaaaggt gtgccgaaag ttttgagctt gaaacaaatt cttgaaaact
    25201 atatcgaaca tcagcgcgaa gtcatcacaa gacggacagt ctttgaaaaa gaaaaagcag
    25261 aagcaagggc acacatttta gaaggtttgc gtattgcttt ggatcatatc gatgaaatca
    25321 ttgcgattat ccgcgggtct aaatcagatg acgaagcaaa agcgacgatg atcgaacggt
    25381 tcgatttatc cgatcgccag tctcaagcta ttttagatat gcgtttacgc cgattgaccg
    25441 gtttggaacg ggaaaaaatc gaaaatgaat accaagaact cttaaaactg attgaagatt
    25501 taactgacat tctggcaaga ccagaacgtg ttacagaaat catcaagaat gaattagcag
    25561 acttgaatca acgatttggt gataaacgac gcacagaatt actagtcggt gaggtcttaa
    25621 gtctggaaga tgaagattta atcgaagaag aagaaatcgt tattacattg acaaacaatg
    25681 gttacatcaa acgtttggca aataatgaat tcagagctca acgaaggggt ggacgtggtg
    25741 tccaaggaat gggtatccac aatgacgact tcgtcaaaaa tctggtttct tgttctaccc
    25801 atgatacatt gttattcttt acgaataacg gaaaagtgta tcgggcaaaa ggatacgaaa
    25861 ttccagaata cgggcgcaca gccaaaggaa taccaattat caatttacta ggtatcgatt
    25921 cgagtgaaag catccaggca atcattgcgg tgacgggaga agcagaagaa ggccactatc
    25981 tcttctttac gacgcgtcaa ggtacagtaa aacgtacttc tgtcactgct tttgctaaca
    26041 tccgaagtaa tggtctgatc gcaattggtt tgaaagaaga cgatgagctc gtcaatgtgc
    26101 tactgacaga tggtcaatct aatatcatta ttggaacaca taacggctac tctgtcactt
    26161 tcaaagaaga agcagtccgc gatatgggac gtacagcttc cggggttaga ggaatacgcc
    26221 tgcgtgagga agattatgtc gttggggcag ccttaatgaa ggaagatcaa gaagtattag
    26281 tgatcacaga aaaaggttac ggaaaacgga caaaagtatc ggaatatcca gtgaaaggcc
    26341 gcggaggtaa agggatcaaa acggcgaaca tcactgaaaa aaatggtcca ctagctggat
    26401 tgaccactgt ttctggagat gaagacatca tgctgattac agataaaggt gtcattatcc
    26461 gtttcaacgt atcgactgtt tctcaaactg gacgttcaac attaggcgta cgtttgatga
    26521 agatggaagc tgatacgaaa gttgtcacga tggcagcagt cgaaccagaa gctgcagaac
    26581 aaacagttga agaacaagga tcagaagaat agccatcaag actaattgtg taagctagca
    26641 agaatgaccg attaaaaaat ctggttattc ctgctggctt ttttgattag ttgaatttct
    26701 cttaaaatat tcgaaactgt tcattctgta ttgcttttga ccaaaataga gtgtataatc
    26761 agagcttgtg agtagtctaa ttaattagat aactctcctt gctcttagga acctaagagc
    26821 cgaaagtcca cagggaggtg aatatcaatg gaaaacacga aatatgaaat catgtacatt
    26881 attcgtccaa acattgatga agaagcaaaa actgctttaa tcgaacgttt cgatgcaatc
    26941 ttgaaagata acggagcaga agttatcgaa tcaaaagatt gggaaaaacg ccgtttcgct
    27001 tatgaaatga acggttaccg tgaaggtatc tatcacatcg ttaaagtatc ttctccatca
    27061 tcagcaaatg ctgtcaatga atttgaccgt cttgctaaaa tcaacgacga tatcattcgt
    27121 cacatgattg ttaaagaaga agcttaattg ttgtttcatg tgaaacaata gaaaacgatg
    27181 agaggagatg actattttga ttaataatgt tgtattagtt ggacgtctga cgaaagatcc
    27241 agatttgcgt tacacagcaa gtggtacggc agtcgcaaca tttactttgg ctgtgaatcg
    27301 taattttaca aaccaaagcg gcaatcgcga ggctgatttt atcaactgtg tgatttggcg
    27361 caaatcagca gaaactttag caaactatgc tcgtaaagga acacttttag gtgttactgg
    27421 acgtatccaa actcgttctt atgataatca gcaaggacaa cgtgtatacg tgacagaagt
    27481 agtagctgac aacttccaat tgctggaaag tcgttctgca tctgaaaatc gccaacaaag
    27541 cggcggattc caaagttctg gtcaatcagc tggcggattt ggcggaaaca ataactctaa
    27601 tcaaacatct caatcatcca acggtatgcc tgatttcgac cgtgatactt ctgacccatt
    27661 cggctcaagt tcaacgatcg acatttcaga cgatgattta ccattctaaa cgaatttgat
    27721 aggagggaaa tagaatggca caacaaagaa gaggcggacg taaacgtcgt aaagtagact
    27781 acattgctgc taaccatatt gaatatatcg attataaaga tatcgaatta ctaaaaagat
    27841 ttatttcaga acgcggtaaa atcttgccac gtcgtgtaac tggtacaggc gctaaaaacc
    27901 aacgtaaaat tactgttgca atcaaacgcg ctcgtatcat gggcttgcta cctttcgtta
    27961 gcgaagacta ataaatccta ggaattgaat gactgatcct tttgatcagc tattcaattc
    28021 ctttttttct gtaaaaataa cctctattcg tttagtcgct cgaatgacga aagttatggt
    28081 aaaatcaaat tagtcatata tgggaggaaa attatggaaa ataaaaacaa tcatttatcc
    28141 ccgaaacctc tcttccttat cctgtttata ttaatcgaag tattggtagt cttaatttta
    28201 ccatttcgtt ttgttagcgc ttcggtcatt ctattgatga atttatgggg tgttcgctat
    28261 tggttgaaaa tgaaacgttg gcttatttta aataaacgtg aaaaaatcca gcaggcttcg
    28321 actgtagctg aaaccaatct agcttatgtc tcagaagtca tgcctgtagg agtgattgct
    28381 tatcagccat caagccaaaa aatcgaatgg ctcaatccat tagcattgaa aatcaaagat
    28441 caaagtggat taacagagga agaattgcta gatacttttt ttactgcaaa agaaaaaaag
    28501 aaaaaccaag tctatctagc agataaaaca tttcagtttg atatggatac agtaaagggt
    28561 gttgtttatt ttaatgatat tacccaaaac cagttgttaa aactccatca gacgaacagt
    28621 cagccggtga ttggtatttt atctattgat aactatgcag atgccattga taaattggat
    28681 gacaaagaga tttcttattt gaactctttc gtcactacac tagtttctga ctggatgaat
    28741 gaataccatg tctttttcaa aagaatcaac gcagaacggt ttttcttcgt agcacagatg
    28801 atcgatctga aaaagatgat ggataaaaaa tttgatttgc tggatcgctt tcgagcagaa
    28861 gctgaaaaac agagctcgcc tatcaccctt agtatgggga ttgcttatgg ctcaagaacc
    28921 ctcgatgaaa tcggtggaga agctcagaat aatttagatg ttgctttagt ccgtggaggc
    28981 gaccaagttg tcgtgaaaga ggtaaaagaa ggagcaaaac ctgtttatta tggggggaaa
    29041 tctgctaaga atgtcaaacg cacgcgtgtt cgttctcgag cgatgagtac cgctttgcgt
    29101 cggatttttg atgaaacagg cgatgtgttt atcatggggc acaagtttcc ggatatggat
    29161 gctttaggct ctgcttttgg tgtcagttgt ctggcacgct tcaaccagaa aaaagcttac
    29221 atcgttatca acgagaacga gatcattcca gatgtagaac ggtgtcttga agaaatccat
    29281 aagcatcctg aattagaaat gcaactaatc tctccagaac gtgccataga gctgaaaaaa
    29341 gaagaggacc tcctcgtgat ggtggattac cataaacctt ctctatcgat ctctcagggc
    29401 ctatatgagc aatttgataa gattgtgatc attgatcacc atcgtcgtgg ggaagagttt
    29461 ccaagtaaac ctctgctgac ttatatcgaa tcttcagctt cttcagcttc agagctagtt
    29521 tctgagctga tccaatacca aagcagcaaa acaaatcgct tagatcgttt tgaggccaca
    29581 ttattgcttg cagggatggt tgtagataca aatagtttca atgtccgtac aactgcacga
    29641 acttttgacg ttgccagcta tttaaggtct tgtggagcag acgcatcctt agtacaatat
    29701 ttattgagct cggatttagc gacatacttg gagatcagca atttgattgc tggaagcgac
    29761 tatgtgactt ctgatattgt tgtggcggca gggacagacg aaaaagagta taatagtgtt
    29821 atagcagcaa aaacagcaga tacattgctt tcgatgatca atatcaatgc agctttcgtc
    29881 attacaaagc ggacagacgg cttgattggg atcagtgcca gaagtaccgg cacgatcaac
    29941 gtccaaatca tcatggaatc cttaggtggc ggaggacact tcacaaacgc agctactcaa
    30001 ctggaaaata cgacagttga ggaaacaaaa cagaagctat ttgctgcaat caaagaaaat
    30061 atgaatcaaa tatatgataa ggagtaatcc aaatgaaagt aattttttta caagatgtaa
    30121 aaggaaaagg taaaaaaggg gacatcaaag aagttccagc aggttatgca caaaattatc
    30181 taatcaaaaa taacttggca aaagaagcaa cgaaaagcag tatcagtcag ttagcaggac
    30241 aaaagaaagc acaagaaaaa cacgaagctg aaatcttgga agaagctaaa aagttaaaag
    30301 aattcttgga aaaagaagat actgtagtcg aattgaaggc gaaagcaggg gaagacagcc
    30361 gtttgtttgg ttcgatccct tcaaaacaaa ttgctgaagg gttaaacaaa caatacaaaa
    30421 tcaaattaga taaacgaaaa atcgaattag aaaatccgat ccgttcacta ggctacacaa
    30481 acgtacctgt taagcttcat catgaggtga cggctacgat caaagttcat gtcgtacaag
    30541 aataacaaat cttgatagcg atgttcagct ggtaagtata accagaagga aaaaagacaa
    30601 accgaaattt atctgagaaa acagctgcag caatgaaagc aaaagctgca aatcgatttc
    30661 agattgattt cggtttcttt tttgggaaca gcaaaatagc ataaagaaaa cgagtataat
    30721 aaaagagaac tattttttta ttacactttc ggtacgaatg atgacttttc tctcattttc
    30781 ttgtaaaatg aagcaattga agacaaggag cgatacgtat gaatgaagtg tggcaggatc
    30841 gaatcccacc gcaaaatatt gaagctgaac aagcggtttt aggctctgtt tttcttgacg
    30901 cagaaacgat cattgatgcc atggagtaca tagagccaaa agacttttat cgtcgtggcc
    30961 atcaaattat ttttgagaca atgatcgagt taaatgatcg taatgaagcg attgacgtgg
    31021 ttactgtcaa agaccggctg gaacaagcca atttgttaga agatgccggt ggtttaagtt
    31081 atctctcaga cttggcatta gcagttccga cagcagcaaa tatcgtctac tatgcgaaaa
    31141 tcgttgaaga aaaatcattg ctgcgtacat tgatccagac agcaacagga atcgttacga
    31201 aaggattcga gcaaggagaa gaagttcaaa caattttaga tgatgccgaa cgcagtatct
    31261 tggaggtttc ggaaaaaaga aatcgaagcg gctttttatc tattgctgaa gtactgaact
    31321 ccacgattga aaatatcgat cgactagctc aaaacaatga agaaatcaca ggtctaccaa
    31381 ctggctatca aggtctggat aaaatgacag caggtttcca gcccgaagaa ctaatcattc
    31441 ttgctgcacg tccagcggta ggtaaaacag cgtttgcatt gaatattgct caaaatgtag
    31501 gaacaaaaac agatcgttct gttgcgatat ttagtttgga aatgggggca gaatctcttg
    31561 taaatcggat gctttgtgca gaaggttcga ttgaggccag ccatttacgt acaggtcagc
    31621 tttcggaaga agaatggtcg aatctgatcg ttgcgatggg gagtctttct cgagcaaata
    31681 tttttatcga tgatacacca gggatcaaaa tctctgaaat ccgtgcgaaa tgtcggaaac
    31741 tagcgcaaga aaaaggcaat ctaggcttga tattgatcga ttatttgcag ttgattgaag
    31801 gtaacggtaa agagaaccgt caacaagaag tatcagatat ctctcgccaa ctgaaaaaac
    31861 tggcgaaaga gctgaaagta cctgtcattg ctctttcaca gttatctcgt ggagtagaac
    31921 agcgacaaga caaacgacca gtgctaagtg atattcgtga atccggatca attgaacaag
    31981 atgcggacat cgtagccttc ttgtatcgag atgattatta tgaaagagaa ggcggagatg
    32041 acgatgatgg aaacgagcca aaaaatgaca acgtcatcga agtcatcatc gagaagaacc
    32101 gaagcggtgc acgaggaaca gttgaactac tgtttatcaa agaatacaat aagttttcgt
    32161 cgctttcgcc aagagaagaa ttttaaagaa gaggttgtga gccttgagca atcccgagag
    32221 ctctcgtaag aagatgcaag gagtaaccgc aggaacgact agagtactta atttaaacag
    32281 atctccaaag ggattgtgac aaaagtcttg tcacagtccc tttttccgaa taaacggtgt
    32341 tcaatcagct gacccttggt attagctcag caaacgtcaa aatatgagga actattttga
    32401 cgtttgtttc tctaatactc aggtcaaaac gctgatctta cgacctcttt tccttaaacg
    32461 gtgttctcct gccaactcct cggtcacaag tcacaatatc atcaaacatg agaagcagtt
    32521 ttttgaaatt gctccttgtg actcagagtt aaacggcagg ctcacaacct ctttcttaaa
    32581 cggtgttcaa aagcttgcat ctgcggtaat acgcccaatc aaacgaaaaa tatgagaagc
    32641 tatttttgtt tggctgttct tattacttga tgcaggacag ctttttcaca acctctgatt
    32701 cacggtgttc caaaagtagc ttcttcgaaa aataagtcga aatttcacaa aaatttgaga
    32761 agcaattttc gtacattcct tcttatttct tgaagctgac cacttctgtt acaacctctt
    32821 ttttaataac cattctaaaa agataaagtt cgttttttaa gcgtttttat aaaataaaaa
    32881 taaaaatcat tcgattttat ttgaaatatg tatctattat tgatacaatg gttcaggatt
    32941 aaataatata gaacgaggtg ttcacatgtc atctgtagta gtagtaggta cgcaatgggg
    33001 cgatgaaggg aaaggaaaaa tcacagactt tctcagtgaa aatgctgaag tgattgcacg
    33061 gtaccaaggt ggcgacaatg cagggcacac aattaagttt aacggtgtga cttataaact
    33121 gcatttgatt ccttctggga ttttttataa agacaagatc agtgtgatcg gaaacggcgt
    33181 tgtagtcaat cctaaatcat tggttaaaga attagcttat ttacatgaaa aaggtgtaga
    33241 aacaagtaat ttgcgtattt ctgaccgcgc gcacgtaatc ttgccttatc atatcaaatt
    33301 ggaccaatta caagaagatg ctaagggcga aaataagatt ggtacaacga ttaaaggaat
    33361 cggacctgcc tatatggata aagcagctcg tgtaggtatc cgtattgcag acttattaga
    33421 taaagaaatt tttgaagaac gtcttcgttt gaatctagat gacaaaaacc gtcaatttgt
    33481 aaaaatgttt gattcagaac cacttgattt tgacgatatt tttgaagaat attatgaata
    33541 cggacaacaa atcaaacaat acgtcacaga tacttccgtt atcttgaatg atgctttgga
    33601 tgcaggcaaa cgcgtgttgt ttgaaggcgc acaaggtgta atgctggata tcgaccaggg
    33661 aacttatcct tttgttactt cttctaaccc agtagccggt ggggtaacaa tcggaagcgg
    33721 tgtagggcct tcaaaaatca ataaagttgt cggcgtctgc aaagcctata cgtcacgtgt
    33781 cggtgatgga ccatttccaa ctgaattatt tgatgaaaca ggagaacaaa tccgcgaagt
    33841 aggacgagaa tacggtacga caactggtcg tccgcgtcgt gtaggctggt ttgattctgt
    33901 agttatgcgc cattctaaac gagtttcagg tattaccaac ctatctttaa actcgatcga
    33961 tgtattaagt ggattggaaa cagtaaaaat ttgtacggct tatgaattag atggcgaact
    34021 aatctaccac tatccagcaa gcttgaaaga gttgaaccgc tgcaaaccaa tctatgaaga
    34081 attgccaggc tggtcagaag acattacagg atgcaaaaca cttgcagaac tgccagaaaa
    34141 cgcacgtaac tatgtacgtc gtatctcaga gcttgttggt gtacgtatct caacattttc
    34201 tgtcggacct gatagaacac aaacaaacat cttagaaagc gtctgggcgc aaatctaagg
    34261 ataaaaacga cgactgaatc aggacgttct taccagagcg agtcgaagtg tttatctata
    34321 cgataataat aacttgaaga ggtagtgaaa gagacgttta gccttattgc cgataggctg
    34381 tctcttgaac actgtttatt cagaataagg gactgtgaca aaaaccgtgt cacagtccct
    34441 ttttccgaac aaacggtgtt caaaagcttg catctacggc actaagccca atcagatgaa
    34501 aaatatggag tgctattttt atctgattgt tcttactgct tgatgcagag cagctttttc
    34561 acaacctctc cactaaacgg tgttctcctg ccaactcctc ggtcacaagt cacaatattc
    34621 aacaaacatg agaagctgtt ttttgaaatt gttccttgtg actcggagct aaacggcagg
    34681 ctcacaacct cttggtaaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac
    34741 ggcaaaatat gaggaactat tttttccgtt tttttctcta atactcaggt caaaacgctg
    34801 atttcacaac ctctgattca cggtgttcca gaagtagctt ctacggaaat aagccgaaat
    34861 ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga agctgaccac
    34921 ttctgtcaca acctcttatt ttgattagaa cttgcgaaaa taaaccggtt aaagtgtgtc
    34981 tagcgcaaga gatttgctat aatagacgat aagggtaaaa tgtaacgaga aggggttgaa
    35041 aaatgtgtat caaattgtaa cagattcttg ttgtgatctg ccataccatg tattagcaaa
    35101 agaaaaagtt gattttttat caatgaatct ccaattgaat gatcaagagt tagtagatga
    35161 cctcggaaag acattcaatt atgaccgcta catgaatcag ctgaaaaatg gtgcgatgcc
    35221 tacgacatca caaatcaatg ttggccgata tttagaattt ttccgttctt atgcggaaaa
    35281 acagattcct gttttatatg tggctttttc cagtggatta agcggctctt acagtagtgc
    35341 gcttcaagcg gttgaattgc tgaaggaaga atatgaagac cctgagatct atgtttttga
    35401 tacaaaagct gcaagtattg gggaagggct tttagtattg gaagctgtaa gattgaaaaa
    35461 agaaggtaaa agcatcgaag aaaccctaga gtggctggaa agtaattatt tgaaagtcca
    35521 ttcatgggta acagtagacg atctgaaata tctagaacga ggcggtagga tttccaaagc
    35581 aagtgctact cttggcagtc tattgagtgt aaagcctatt attacggtgg ataaagaagg
    35641 aaggctgacg aatgttgaca aagttcgagg aagaaacaag tcgatccaga caatcgtcaa
    35701 tgagacggta aaaacaatcg ttgcaccact tgatcaaatc gtttatgtgg cttacgctgg
    35761 ggatctagag agcgcggaga aggcaaaacg gcttttggaa gagcagataa agatgaaaga
    35821 tgtgaagctt tatcccttag gaccaacgat cgccagtcac acaggctatg gctgtatcgc
    35881 gattttttcg atgggaatca gtcgataaaa gcagtaactc attctgtaaa aaagcccaga
    35941 aattgattgt aacaaaaaca gcgactctta aaagatagat gagcatccta tctcttagag
    36001 gtcgctgttt ttttattttt taagctaaat aggccattat gcccataact cgttcaattg
    36061 tttttgaata tctgcatttt ccaaaaattc atcatatgtc gtatcagctc gatcgatcac
    36121 acctttatcc gaaacggcaa tgatgcggtt tgccaatgtt tggataaatt gatggtcatg
    36181 tgacgcaaat aagattgagc cagtaaatgc catcaagccg tcattcaatg ctgtgattga
    36241 ttctaagtct aaatggttcg ttggatcatc taatacaagt acgttagctt tcgaaagcat
    36301 catttttgaa agcatgcaac ggactttctc tccaccagat aaaacattca ctggtttcaa
    36361 tacttcttca ccagaaaaca acattcttcc taagaagctt cttaagaagg tgttatcatc
    36421 ttcttcttta cttgcatatt gacgcaacca gtctaaaatc gttagatcag tatcgaattc
    36481 tttcgttgta tcctttggta aataagaatt acttgttgtc acaccccaac gtactgttcc
    36541 agtatctggc gtaatttcac ccatgataac tttgaatagc gttgttgttg ttatatcatt
    36601 ttctgcgacg aaagcgacct tgtcttcttt gctcaaatta aaagatatat catctaaaat
    36661 tttctttcca tcaatcgtta cacttacatt ttctacctgc aataagtcgt ttccaatctc
    36721 acgttcaggt ttgaatccaa cgaatggata acgtctagaa gaaggttgga tatcgtctaa
    36781 agtaattttt tcaagcattt ttttacgtga agttgcttgt tttgattttg atgcattcgc
    36841 actaaagcgg gcaataaatt cttggagttc tttgatttgt tcttcttttt tggcatttgc
    36901 gtttgcttga agtttagccg ctagttgact agattccaac caaaaatcat aatttcctac
    36961 ataaagtttg attttaccaa aatctagatc cgccatatgt gtacatactt tgttcaaaaa
    37021 gtgacggtca tgggatacaa cgatcacagt attttcaaaa ttgatcaaaa attcttccag
    37081 ccaattgatc gattggatat ccagaccgtt tgttggttcg tctagcaaaa gaacatcagg
    37141 tttaccaaat agtgtttgtg ctaataacac ttttaccttt tgtccaccag ttaattcact
    37201 catttgctga tggtgcaatt cttcagggat gttcagacct tgcagtaaaa cagctgcttc
    37261 tggttcagct tcccatccat taagctcagc aaattctcct tctaattcag ctgctcgaat
    37321 accatcttcg tcagtgaaat cctctttcat gtaaatcgca tctttttctt tcagcacttc
    37381 atacagacgc ttgtgtccca tgatgactgt ttcaagtaca gtatagtctt catagtcgta
    37441 atggttctgt ttcaatacgg ccatccgttc atctggtccc atagtaacgg aacctgtgga
    37501 aggctgcaga tcccctgata acactttaag gaacgttgat ttacctgcac catttgcacc
    37561 aatcaagcca tagcagtttc cgggggtaaa tttaatattc acatcatcaa atagtttgcg
    37621 gtctgaaaag tgcaaactca catcatttac agtaatcaat ttttttcctc acttttatca
    37681 ttattagttt tgacaagtct tatagaatta tataggggaa aggtaaaaga ttcaaggcaa
    37741 tcgaacattc tttgtgtttc acgtgaaaca gaatgaaaaa aataaaaata aaagcggagc
    37801 gaaaatagct actataggat ttattagttt gcaacagcat aatttttgac gttatttata
    37861 agagggagta ctataaaact gtaaaagaaa tgaaagaagg attgaaaatg gatgaaaaaa
    37921 gaaccatcga ctggggctca ttgattttgg gaattttatt tgtacttgtc tcattgttat
    37981 catttcaaga ccctgtcgga aatttagttg caattgtagt agtctttgcg atttttgcct
    38041 ttattaaagg gatatttgaa ctgtttgtac ggaacagatt aaaagagcta acaggatata
    38101 aaggaaagat gcccttaata atcgggatca tcgatattct agttggcgtc tttttcttat
    38161 tcaatattgg tgcaggagtc gcagcattgc cttttgtttt tgcagtatgg tttattgctg
    38221 attcagtttt agcgttattt actgctgact tggcaagagg agtaagtgaa ggatattatt
    38281 ggtttacgat catcgtcaat attttaggaa ttttattagg aattttctta ttgtttaatc
    38341 caatttcttc tgcgttgaca ttaagctttt tagttggatt ctattttatg ttatttggta
    38401 tcacacatat cgtctatgca tttagataag taaaatcaaa caaataaaaa agccggcttc
    38461 cgattacagt tttactgttg taattggaag ccggcttttt tatcatggac aaatatgcac
    38521 gaggtgattt ttaggtgtcg agacaaattt atgcaaaaat gtgagaagct atatacacaa
    38581 attttatctt aatactcgaa gcatagcgca gttgtcacaa cctcttttca tataattcat
    38641 tcaatactgg caaatcatgg acttcatatt tttctttgaa tgcttggatt tcttcttcag
    38701 aatattttct tggatctaaa tgcagatctt ctactggcaa tgggcgcttg ttattgatct
    38761 tcacatcgat tactacagga cgatctgatt ttgcagctgc atcaaaggca aatcgaagtt
    38821 gcgagtattc tgtgactgta aagctatttg ccccgagcgc ttctccaact ttaccgaaat
    38881 ctgcatcttc taaaaataca ccaaatttct tttgttccgt atcttcttgt tctgcttcga
    38941 tgaaaccaaa agaatcattc gaaaagacaa cattaataat tggaagctga tatttgactt
    39001 gtgtaatgat atcttgcatg accatagcaa acccgccatc accacttaag gtaaatactt
    39061 gtttttctgg gtagcttagt tgtgcggcaa ttcctcctgg cacaccatta cccatagttg
    39121 cgaaccatcc agatgtcgta tgtttttgtt taccgttcat attcaataaa cgaatagaat
    39181 ggatagtcgt gttaccgaca tctgtgacga aaatcgcatc gtcttcagca atacgattga
    39241 tttctttata gacagcctct ggacgaatcg gttcttcctc tcgatcttca aaagatttca
    39301 accaatttac ccatttttct ttattttctt gatttgctag gtaccagcta tcagcagggc
    39361 gagcatcccc taactcgaca agtctttgca aagctgtgtt tgcatcaccg aggatcgaca
    39421 aagatgtttc atggcgtcgt ccaaattttg acgcatcgat atcgatttgg ataaattcag
    39481 cagttggatt aaaaaatgca cgtccaaatg ggaagtcgct accgacaaat aagatcagat
    39541 cggcttctgc caatgcttca tttccgggtt tagtagcgac acgtccagca aaaccaagaa
    39601 agttttcata atcatcagga ataattcctt ttgctagaac ggaagcgaca acaggaactg
    39661 aaaaatgttc tgagaattct ttgatttgcg gaaatccgtt tcgcgttcct tgaccaacat
    39721 aaagaactgg tttttttgct ttttcaagat aaggcaaagc agctagcaaa tctttttctt
    39781 ctggtaatat cacacttgtt ttgtgagtgt gagcggtgga gaaaggttgt tcgtcaattt
    39841 cttcaaaacc aagatcaaca gggatagtca cgatagccac gcctttatgc tcataggcgg
    39901 ctttaatggc ttcatctact acatgcggaa gactttgtgg tgtcatgact gtacgattgt
    39961 atacgctaac atctgcgaaa ataggatttt catttagttc ctggaaagag ttatagttca
    40021 tggatgtaga agcaacttgt cctaagaacg ctactagagg cacatggtcc atctgtgcat
    40081 catacaaacc attgatcaaa tgtgtcgcac caggtcctgc agagccgaag acagcgccga
    40141 ctttccccgt taattttgca tctgcagcgg ctgcgagtgc gccgacttct tcatgacgaa
    40201 cttgaatgta gttgatttcg gttttttctt gatatagcgc atccataatt gaattgaaag
    40261 atcctccggg aatgccgtaa atatggtcga taccccagct ttcaagaact tttaccattg
    40321 cgattcctgc attgattttt gacatggtgt ttcactcctt tagcaatgat gatacataaa
    40381 ttttttgtat ctagagtata gaacttttta tcgaaaatcc caactaattc gtcttttcac
    40441 aaaaatgtag tcatgttttt gggaatatgc tagagtagta catagataga ttcaagagag
    40501 gggaatggca tggttgaatg gctattgaga cttgaacctt ggcagcaagc acttgctggg
    40561 acagctttta cttattttat gacagctctt ggtgccgggt tggttttttt ctttaaagaa
    40621 atcaaaaaag aagtgctaaa cttgatgtta ggatttgctt ctggtgtcat gattgctgca
    40681 agtttttggt ctttgttaga tccggctatt acaaaagcag aagaaaatgg agatattgct
    40741 tggctagttg taagtattgg gtttggttta ggcggtgtgt ttttatatat ggcagataaa
    40801 acactgcccc atatgcattt tggaccacaa catgaagcag aaggattgcc tacccattta
    40861 aaacggacga tcttgcttgt tttttctatt acattgcata acattcctga aggtttagcc
    40921 gtgggggtag cattcggtgc agcagcaact gcggataatc cgacagccgc tatattagcc
    40981 gctgtttcgg tggcgctagg tattggtatc caaaacttcc cagaaggagc agctgtatca
    41041 atcccgttgc gacaagaagg tctgagtcgt aaaaaggcct ttgtttacgg acaagcttct
    41101 ggaatcgttg aaccaattgc tggagtgatt ggagcgctac tagtaacgaa agtggagctg
    41161 ctgcttcctt atgcacttgc ttttgccgca ggagcaatga tttatgtcgt ggtggaagaa
    41221 ttgatccctg aagcacagca gacattgtcc agcaaacatc attttgcagt ttttggcgtc
    41281 atgagtggat ttatcattat gatgattttg gatgtggcat taggataaat aaaaaaaata
    41341 tatatgatat atcaaatagg gccgcgaact tatatcgcga ccctattttt ttagtaagtt
    41401 atatcataat gaagtgaatg gtatcataca ttaataatag ttttttctat gtgtatttcc
    41461 tttgatccag cgaacaagcc agatgataag tgcgattggg attagaactt tgaccgcaaa
    41521 ccataaaagc ccgcttagga cactgacaaa aagactgatg acgaagctag ctgcaattag
    41581 cactaaaaga accatgaaga tatttaagaa catatttttt tgacgcatac aaaaccctcc
    41641 tcttgttcat tctttactat agaaaaagta taacagggat tgtttaaaaa cacctccaac
    41701 tgaagactga tttttacttc atctacttaa atgatcaaac aattgctttt tctctggttt
    41761 atcatctaaa atagagcgga aaaggaggag aatatcatgc ctaaaaatcg tcttgaagca
    41821 tttacagatg ctgtaatcgc gattatcatg actattttag ttttagaact tcatgaacct
    41881 aacggagaca cgtgggaggc gctcgctgca ttaggttacc gattttttat ctatattgtc
    41941 agttttatca ttttagcgat ttattggaac aatcatcatc atttatttca agttgtacat
    42001 aagataaatg gacgggtctt atgggcgaac agtttctttg tttttgcgct ttcgcttttt
    42061 ccgtttgcaa cttcatggat cagtgagtac atcaatagcc tggctccaga aatgacttat
    42121 ggttttgtta ccttgaccgc taatattgcg tattatatct tggcaaaaga acttgtcaaa
    42181 gcaaataaag gccacgagaa agcattgaag gcgatgttga ataattacaa gaaatcgtat
    42241 ctatcgattg gtttgaatgt gttaggaatt gtcttagggt atttagtagc gccagtagcc
    42301 gtgctgatcg caaacatcgt gattctagct gcttggatca tcccaagtcg taccatcgaa
    42361 tcacaatatc ggtaaaatga tccgtgttta aaatttaaga gaaaaatata gaaaaaataa
    42421 ataaacgatc aaatatccga gtgatactag tattcaaaga gggatgcaga tggatcaaaa
    42481 aagaattcat gtaggactga ttactagttt tgtcacgatg cttatttatt tggatcaagg
    42541 tcatttgact tggacagtag ttggtgtcgt aggatttttg acattattca cagcaataaa
    42601 aaaataaaca tctttatgta atctgatgtt ctatctattt aagaaaagca tgtttacagc
    42661 agtatgattc tgttgtaaac gtgtttttat ttgtggaaaa tttaattttt agaaaagtgt
    42721 atcgaaaaat agatagttag tttttccaca gtggataact tcgtaagaga taaaaataaa
    42781 aaattagtca aagaagggcg tatagatttc ttttgatagg agatatacaa cagaaatgaa
    42841 taaatattaa cgtgttttca aacagtataa aacggtgtgg tttttggaat aaaaaaataa
    42901 catatctcat tttacacttt tgttatttta tacttaaaaa ataacgacac agaaaatacc
    42961 gtgtctcaga tttctctact acttctaaaa actactgttt ttttcctttg aaatgccttc
    43021 aaaaagtagg atcaggcaga atatactggc agaatcaagg agaagggagc ctaaataagg
    43081 agaaaaacca tagaaaatat aaagtaatta cttataaaac aagcttttta tagaaaaata
    43141 atatacctga gtagggtata aattaagacg gaattccttt ctagattgag atattgacta
    43201 ggaagaatgt taagatttta agcctttaag ctaaaaaaaa accctttttg ttaaataagg
    43261 ggaatatagc ctgtcagttt caaactgcaa gtcgtcctgc tgcaataata tagtagatta
    43321 gagatgaaaa tagatttttt taaaccaatg actgaataaa aagaccgtca tagatacaca
    43381 ttggaatgtg tctattacgg tcttttttta cgaacgattt tattgaagac ggacagttcg
    43441 ggtcaaaaat aaaaaagcta cgatcagaaa taagaataaa atgtatccca aaataatggc
    43501 tagacggtct aacttatttg tcgatagatg tttgtttaga agttgatagg cccataaacc
    43561 tatcagtcct cctgttgtat tagttatcaa atcagtgatg tccgctacgc caataccgaa
    43621 taggaattga atcaattctg ccaagaagct tacaaggaaa ataatcccta attttttaga
    43681 aaaagaaagt ctcttgaaat tgacattcaa aagcacccca aaaggaaaaa agacaatcaa
    43741 gttataagtg gtctcacgta ataccgtcgt attttcaaaa gaaaaagtag aaaaagggac
    43801 gagattgaca ttgctgtaag aataagtgag aaattgtgga agattaaatg atagcttgaa
    43861 taaaatcaac cataatagaa agaataaata aatccctaat aaaaattttg atacataccg
    43921 catagacatc tcctccattt aaaaagtata ccatcgaaaa ccgctgaaaa atcataaaaa
    43981 agtatgaagt ttaaggacca acgtagttat cgtacgaaaa ttagaagctt ttttttgttg
    44041 ggaatccggt ttctttaaca aagctaagat agcgagttgc ttggaaaagt tgctatcttt
    44101 tttctgtcaa aacgactcgg aatgttcgtt ttttgttcta atttctccaa gttgtttact
    44161 ttttgatact aagtttatga aaaatcaaga aatagttgtt atactaggta atgctgacaa
    44221 acgggattgg catttcatct tggttcagct ttttttccaa ttactaggaa ggagggatag
    44281 attgttcaag acttattttc gtttcaataa aatacaagat aatccttttc gtatcatgaa
    44341 tctgatgcta cttatcttta ttgtattatg gttaggttac ataaatcatg attttttgat
    44401 ttcaagtttt tcatcattag ggatctttac ttttttctat tatcaaaaca taccgatgaa
    44461 atatttgctg aaacgtatgt ttctgatcgg ttgcggactg ttggttgctt tcgttttggg
    44521 gatcttatcg acttatgttt tatggcttga accatttgcc gtagctttgg ttgctttttc
    44581 cagcagattc gtgttgcgat tattccatat ttctaaacca ggtggcttgt tttttgcgat
    44641 gctttctgcc atgggaacga gcatgcagct gccaatcgct caattaccga tcgtctcact
    44701 ttattttttt atgggtgtcg tttttgccct gattgcggca gtgattacaa aattactgga
    44761 ttcacggcct gagcagacaa ttgaaaaagc aactttaaaa gaaagatttc acgaagagcc
    44821 tttagtgatc attgattctg ttttctacag cgctgcctta tttctttccg tttatgtcag
    44881 tcacggcttg aatctgcata atccttattg gttgaccttg tcatgtgcat cgattttgct
    44941 agcagaaaac ttggatgcga tgaagcatcg acaagtccaa tatctgattg gatcgatggg
    45001 tgggttatgt gtgtcggcat tcttgtcatt tgtgccgttt acgcagttgc agaccatttt
    45061 tctgatcact tttctatatg gaatcgcaca atttctagtt gctagaaatt atgcagttgc
    45121 taatattttt cttaatccga tggcgttgat gctatctaca cttattcgtg gagcatactt
    45181 gatttctttg atcgaatatc gttttttagg gatcgtcata ggaagtttca tcggtttagg
    45241 tgttgcgtgg gtaatgacgg ttggtttgca acattattta acggttgttc gtcaaaaatt
    45301 agaatagaag gacaaatata tgtgccaaaa gaggttatga caagattttt gtcacaacct
    45361 ctaattcaag gtgttcaaaa gccagattct cagcattaag tcaaattcac acaaaaatgt
    45421 ggaaaggaac tttcaaaaaa attttatatt tattctatca aaaaattttg tttatgatgg
    45481 taactgaata aactttcctg agatggtcaa tgctttcctt gaaagtctta cagatattct
    45541 ttcttcatag aaagtttaag ttttatagtt agtgtacaat aaaagtatgt ttataccata
    45601 tggtgtccgg ataatcagtc atttaaacaa tgaggttcaa agatatgaaa aggggaaatt
    45661 tgatgaagaa aataagcaat gaaatccaaa ttctggcaga aactttaact cttcccaaag
    45721 tcgttataga gcaaatgatt gtacaagcaa aaaacatcct tgatgaggtg tttgagcaat
    45781 atagtcatga actaatggat cctaataaag caaaggcgac tgcaaagaaa atagacaaag
    45841 tctatgaaga ggaacctttt gcagcattag ctatttatct atatgcagct tctcaaagtt
    45901 ggaaaaaaat ttatcaacca ttgaagattc caagaactat ctatttggca acaatgaatg
    45961 cttttactag atttattcat gaacatttcc aagtaacagg aagctatcgc tttgaccgtg
    46021 gtttttggat ttggcattac actagtggct tgatctttcg gattggtgaa ttggagtacg
    46081 aaatgacata ttttccgaaa gggtacacgg atctaagatt agaaggaaag cagtgccttt
    46141 ctcttcatat tccttccgat gcagatttat ctcagaataa gataagagat agttacgaaa
    46201 gtgccattcg tttttttgaa ctttattttc ctgattacca ttaccaagtg atgtacacag
    46261 atacttggtt actatcaccc aatcttacta aatggttgaa aaaagagtca aaaatctgtc
    46321 tttttgcagc cgattatcga ttattatcag ttgatgaaca ggacgatagt ggagtccctt
    46381 ggatctttgg acgagtagat gcccaaatac atgattatcc agaaagtacg agtttacagc
    46441 gacaagcaaa agagcaattg cttgcagacg agcacattgg ctctggctta ggtattctta
    46501 cttcataagt ttagtacttc gaaatagttt aaaagagcgt gagacaaaag taaagaacac
    46561 ttttgtctca cgctctaaac acgtataaac ggcggaagca gaagcaactc cttcggaaat
    46621 aagctgaaat tcacaaaaat ttgaaaagca attttcgtga atttcttctt atttcttgga
    46681 gttaaacgct tctgtcccag cctctttttt agtgttctat cgaacacaca gtacgttcaa
    46741 taggtaaact agctataaca atagatatta aagttaacgg acaagagggc cttttttagg
    46801 tagctaaaac gtaataatga aaatttattt ccagagatag gagtcaatca gctagtctga
    46861 tcgactgttt taacaagttg actttcattt taacttttga taccatttaa aacacaaatc
    46921 gtaattgttt cgatttgtgt tttttagcat gactacaatc aaagaagaaa gtgggtcgtc
    46981 catatggaaa aaacagatat ctcaagtgca taccgccgct tgaaaagccc aaatatcaaa
    47041 acacgaaaac gtgcgctgaa gatcatcaaa gatgtgaaac ggaatagtgg gaaaaggtaa
    47101 gaagaaggaa acttaattaa aaaaatagcc gaaaaacgtt tttcggctat tttcaataat
    47161 cggtttttgt gtaaggtttc cgaaagaact gctgttgatt ttccattttt aacatatgat
    47221 aaattggtag aatctttctt ttcaaattga taccattccc taattccagt tatatagtta
    47281 actacagaac cacaaagcac gtacgtttat aaaagtatta tctgtagtta tttttcaatt
    47341 ccctttcaac ctcttatttt gaccagtagt attgatcact ttacctttta acacctttgt
    47401 tcgtttttga aacattttta gtcaagaatg gaaacgtaac tacataatca aaggttttgc
    47461 gaaatatttc atgaaatatt tcatgtagaa gcgagcaata cggttgcaaa taaccattat
    47521 cgtttaataa gcagttacga aagctcccaa tatctctaac gttcagctca ctccatttct
    47581 tttcttcaaa aaaatcagtg attcgtatct ctttctattt gtcgaaaaag ttaactttaa
    47641 aaagtaacgc cgaaaaaata tgcaaaaaaa taaaaaagca gttactattg ctagaataac
    47701 atcaaggaat aataagtttt ggttttcaga taatagtcga taagttgtgt attggaattt
    47761 tagatacagt aataaagtat ttttcatgaa attttgtgag aatcactatt acaagtatct
    47821 ttaataaaat taatggttaa ggaggaactt aaagtagaat gtaaatgaat agttgtagtc
    47881 agtcgattgt gatactagac tcaaagttgc aggaataagt ttttcaattt gtgattggaa
    47941 gataaaaaat gaaaaagaag ggcttttttt tatactttgt tgattgtagt gtttattttc
    48001 cctctgttta gccaagtaac attttctatg actcaaccag tttcaagtga ggaacatgat
    48061 aacctttttc gtgctacaga agagtttaag aaatatcagg aaaatattgt tccggagact
    48121 ccattagcta gtgagccaat tactgatatt gatggaaacc aaataggatg gtatatacag
    48181 tacgaagtta tggtggtaaa taatgactca atagtaaaaa atacagtagg cttagagcta
    48241 acaccgattg aaaaggtgag ttcattgtta acgtatattt atactgatga aagtgacgag
    48301 actgagatca ttttaacgga ttactcaaaa attgctactg ataaaaagta tatattgtgg
    48361 atgtagacac tagtgaaata ctttatgata tagaaattga tgaaaattta ctagatgtag
    48421 cacaagaaat cgatcatcaa aagcaggaag ctattcgata tgctggtaga aaagggaaaa
    48481 gaaaatattt attacgtgaa tgtagcaaaa gttagagaag atgaaaatga gtggaaagaa
    48541 ttcaagagtc gctactcaat taactcgact ccgacattta cagtttacag agaaggatcg
    48601 atagaaaaaa ctgttttttg gactaaagaa agtggaatgt ctttagctga agtagaagag
    48661 tttttggatt atgttagtat gcaacagtaa gggagttctt attatgaaaa attttgacac
    48721 atattatgtt attgtttttt cgatatcttt gctgttaata ttactaactt taatgcagta
    48781 taaagagtat ccagagtatt ttattttaac ttttgtatat ttagtaagta gctacacact
    48841 tctatataaa ttcagaagtt cttctagagt ttctaaagtt tgtttcttaa ttagcttatt
    48901 gattctataa tatttttgat ttatatagga aattaaaaat attatagaat caacactcag
    48961 agaacgggtt ggtttttaat agatttaata agtactgata atgaaatttc tcctggttgg
    49021 gaaaacgaag ttggttaccc tgtagaagaa ttttttcaag attactttgc ggagtatgcc
    49081 gataggataa tgagagatta cgtaacagat aaaactcaag aagtcatcaa tcaatcccag
    49141 tcattaaatg aattatctga taaggcgaaa gaagaagcag ttgccattat ttcttcaggg
    49201 attagtgact atattgatat gagtggtgaa atcaattatg gcgataaaga caaaattgta
    49261 cgcatgataa aagcttttat caaaactttt gatgtgaagg cagatcttaa gtttaatgat
    49321 acttacctag taggaaaatt aattaatatc cttgggacag agaaagatac ggaaacgttt
    49381 atttcctctt tgtctatgtt gtttacagat aagcattttt caactcagct tggtggagag
    49441 gaactagtgg aaatctttta accattacgc ccagcattaa taaaagtata tcaaaaaagt
    49501 actcctgatg atttttaaga ttggtttgag aaataatgtg aaaacactat ttttaatgtt
    49561 aattatagat agagatgaac gcgtcatatg gttaaaagaa tgaaaaagtc aaagatacac
    49621 tgctatattt cactaaggat atagcagtgt atctttcatg tcgtttcact ggcagttttt
    49681 tataaaagga ggtgtgcatt tcagttgctt ttctttggta gttagttgaa tcgtttaaga
    49741 attaacggat gtggcagaca ggtgctctgt ccaaaaacca gtaaaatctt tgatggttcc
    49801 atctttattt agctgtgcct gttcaaatac tgttttgttt ttaccgaatg gatcaattgc
    49861 aataattgtt ccgatccccg cacgtttggc agcaagtaat cctgagtaag catcttcgat
    49921 aacaagacaa tcagccggag ctaagctcag tttgtctgcc gctttaagaa aaatatccgg
    49981 ttgcggtttc ccagggaaag agccgtcgtc atagacaatc ttgtcccagt caaaccagcg
    50041 ggctaaatcg aaaatatcaa aataaaaagc aacattctct ttgacagtag ccgtggcaat
    50101 cgttaatgga atctgttggt cagtcagctg gtcaagagtc gcttcaagcc cttttgtcaa
    50161 ctgaagctcg ttttcatttt gcaagcaaag catacgataa tagctttctt tttcttctga
    50221 caatacggcg atctcagagg cggtcaaatg ctctgaaatg aaatgtttca aaatctccgt
    50281 attcgtccga ccatgaatat tttttaaaat atcctcgtct gataaaccat cttttgtatg
    50341 atcatgtatc atatgcagcc aagcagcttc atgcagatga gagtccaaaa acattgttcc
    50401 gttgaaatca aatataatcc ctttcatagt tacgctccta tagtggtatt ttcggttgaa
    50461 tcagcaattt gcagatcgac atattgtgca tagtgctctt gaacctcccg cgagatctgg
    50521 cgatccgtaa tgagcagatc gaaatcatgc aaattataaa acacataaaa atcatctcga
    50581 ttgaattttt tattatcaac gagtagatat ttcttacggg aattatttag agcgatctgc
    50641 tgtgcttctc cttcttcggt actgtaagta gagatcgctt cgttgtgaac gccatttgaa
    50701 ctgataaatg cttttgtaaa ctttagtctt cttaaattgt cgttggtgat cggtccgaca
    50761 aatgcgccgg tatttttccg gaaatcaccg ccaatcagta gaatttctgg tccatctgct
    50821 tgagcaagaa tatcaaaaac tggataatta tttgtaatga tccgaatttt cttgttcagt
    50881 aaatgcgtcg ccaatagttc gattgttgta cctggtccta agaaaatcgt ttctccctcg
    50941 tgaatcaagg aggctgctgt ggcagcaatt tctttttttt cttgaatctg cagagtggct
    51001 ttttcagtgt gagaaagttc ttgatctaaa gtgtaggaaa gactttgagc ccctccatgg
    51061 acacgcagca gcttgcccga tttttctaat tcatctaaat ctctgcgaac ggtcatatca
    51121 gaaacatcta attgattgat gatttcatta acggtaagga ttcctttttt attgaccatt
    51181 tctacgatag taagcaatct ttcttttttc aacattgtct tcacctctaa tttaaggata
    51241 atctatcata taaacggaca acagtcaatc taattcgaac aaaagtaaac atttagggtg
    51301 gtttttatgt ttgttacaat agattttatt gctgttttct ggtttttatg attatttgtg
    51361 tttgtttttg ttgacaaatg ttttggatgc gtttacaatg caatcagtta gaaagagcga
    51421 aaactgatta tagatttgag gagagatgta catgcttaaa ttaccagaag attttatttt
    51481 tggcggagcc acagcagcct atcaggttga aggagccact aaggaaggtg gcaaaggcgc
    51541 tgttgcttgg gatgactttt tagaggaaca agggcgattc agtcccgatc cggcaagtga
    51601 tttttatcat caatatgcaa aggacattga attgtgtgaa cgttttggtg taaatggtct
    51661 aagattatcc attgcttgga gccgcatttt tcctgatgga gctgggaaac caaatccaga
    51721 aggaatcgct ttttatcatc gtgtgttcga agaatgtaag aaaagaaacg taacgccgtt
    51781 tgtgacgttg catcattttg atacccctaa acgtttgttt gaccatggag attttttgaa
    51841 tcgagaaaca atagaagcat ttgtttccta tgccattttt tgttttcatg aattcaaaga
    51901 agtcaaggtg tggagtacct ttaatgaaat ctatccagtt gcaaccaatc aatatttgtt
    51961 aggtgttttc ccaccaggaa tcaaatatga ttttacaaag atcgtcgcct gtcttcataa
    52021 tatgatggtt gctcatgccc gtgtagtgaa ctatttcaaa gaaaacgaac ttccgggtga
    52081 aattggtgta gttcactcat tagagacgaa atatgcggca acagacgcgc cggaagataa
    52141 gcatgctgcc tttttagacg atgcattgtc gatccgtttc ttattagatg ctacctattt
    52201 aggctattat tcaactgaaa ccttgactgc tcttgatgag atatgtgaag caaatcaggc
    52261 cagctatcat tttcctgaag aagatttcgt tgaattgaaa aaagcatcca cgcgtaatga
    52321 ctacttaggg atcaatcact accaatgcca ttttgtcaaa gcttacgatg gagaaaatgc
    52381 aatccatcat aacggtacgg gtgaaaaagg gacctctgtt tataaagtga agggaatcgg
    52441 agaacgtatt tataaagaag gaattcctcg aactgattgg gactggctga tttatccaga
    52501 aggtctatat gacttgttgc tgcgaattaa aagcgattac ccacattaca acaaaatcta
    52561 tatcactgag aacgggatgg ggtataaaga tcagtttgaa gatggcatta ttatggatca
    52621 gccgagaatc gactatttga gagtctattt ggaatcctta agcaaggcga taacagccgg
    52681 ggtaaatgtg aaggggtatt ttttgtggtc gcttatggat cttttctcat ggacaaatgg
    52741 gtataacaaa aggtatggct tgttttatgt tgattttgaa acccagaagc gttacccaaa
    52801 agaatcagct tactggtaca agttggtcag tgaaaccaaa acgattattt aataagtgat
    52861 aatggaggaa gaaaagatga ataaagagga attacaaatg cttggttttg agatcgttgc
    52921 atattcaggc gacgctcgca gtacattatt gaaattattg aaagaagtaa gacaaggaaa
    52981 ctttgaacat gttgattcgg cgttgaaaga agccgacgaa aatttaaccc ttgcacataa
    53041 ttcgcaaaca aaaattttag cggaagaagc atctgggaaa gagatggaga tgggattcat
    53101 ttttatccat gggcaggatc atttaatgac cactttattg ctgagagatc tgattcaaga
    53161 ctttattgta ctgtacagac agaatcaagg ataggagaag aacgctatgg atggaatcat
    53221 taaacaaatc gaaaaaggga aaccattttt tgaaaaaatc tcacgtaata gttatttagg
    53281 agccgttcgt gacggatttt taacagcgat gccagctatt ttattttcaa gcattttcat
    53341 tttgattgct gcggttcctg agatttttgg ttaccaatgg cctgaatctg tctccacatg
    53401 gctatggaaa gtctataatt attcgatggg tgttgtaggg ttactcgttt cagcaaccac
    53461 tgctcgctgc ttggctgatt cgatgaatcg tcgcttaccg aaaaacaaag taatcaacac
    53521 cacctctgtg atgctggcct ctgtggtaag tttcctgttg ttaagcgtct ctccgattga
    53581 aggtggattt tcaacggaat atatggggac aaagggacta ctggcttcct ttgtcgctgc
    53641 atttttaaca gttaatttat ataagttttg tgtgctgaaa gatattacca ttaaaatgcc
    53701 taaagaagtt cctggaacga tttcgcaaac cttccgagat atttttcctt tctctttttc
    53761 agtatttgcg gccgttttaa ttgatttagg cattcgacaa atcttccaaa tctcatttgc
    53821 agaagcaatc attacggtgc tgcagccgct atttacagca gctgacgggt acttaggaat
    53881 cgctattatc tggggagcga tggcgctgtt ttggtttgtc ggtgttcatg gaccgtcgat
    53941 cgtggagccg gcaattgcgg caattatcta tgccaatgtg gaaaccaatc tgcaattgtt
    54001 caattccggt gaacaagctt ctaaagtact gacggtgggt ttagggaatt ttgtaggaac
    54061 tatgggagga actggggcaa cattggttgt tccttttatc ttcctactct ttgctaagtc
    54121 taagcagttg aaggcagttg ggaaagcttc ctttattcca gtaagtttcg ctgtcaacga
    54181 accattgcta tttgcggcac ccatgatttt gaacccttat ttttttattc catttttgtt
    54241 aacacctgtt gtaaacgttt gcctgttcaa gttttttgtc gatgtattgg gcatgaacag
    54301 ctttatgtac gttttgcctt gggcaactcc agcaccgatc ggtttggttc taggaacggg
    54361 catgggtatc ttagcttttg ttctagcagc ggttctaatc gtcgttgact tcctgatcta
    54421 tctaccattt tgcaaagcat acgatgctgt cttagtagag aaagaagcac aaaaagcaga
    54481 ggtgatcgca accgaggaag gtgcttctgc cgatgtacgt gaggaagtac ctgtggcagc
    54541 gagtcaagtt atcagcgatg caaataaaga aatcaatgtg ttggtacttt gtgctggcgc
    54601 agggacaagt gcgatgttag ctaatgcttt aaaaaaaggt gcatctgaat cgaaagcacc
    54661 gatcagtgca atggcgggtg cttatggttc tcattacgaa atgctgcagg attttgatat
    54721 ggtggtctta gcaccgcaag tcaattctta ctatgatgat atcaaagaag acaccgatcg
    54781 cttaggaatc aagctggttg cgacaaaagg agcagaatat atcggattaa cgagagatcc
    54841 tgaaaaagct gttcagttta ttctgaacca atttcaataa aggaggagcc ataatgaaaa
    54901 tgggaatttg gttgcgtaaa gctgttttat ttgcagctgt gttaggggct ttgggggctg
    54961 tttcaaaaac tgttgaagca tctgccagcg aatttattcg cggagcagat atttcgatcc
    55021 tgtcagatat ggaaaaatct ggtgcaaaat attatgaaga cgatatttca aaagatgcct
    55081 tagagatttt aaaaaataat ggtgtcaact atgttcgact gcgtttgtgg caggatcctt
    55141 ataatagtaa tggagaaagt tatggagcag ggacaaatga tctggaaacg acgattgacc
    55201 ttgcaaaacg agcaaaaaat ctgggactta aggtgctgct ggattttcac tacagtgatt
    55261 tttgggttga tcctgggaaa cagaatcttc ctaaagcatg gcaaggtctg acctttgaag
    55321 aaatgaatac ggcattgtac gactatacaa agaacgttct gtcggaaatg aagcagctgg
    55381 acgtttatcc tgatatggtt cagatcggca atgaactgaa tagcggaatg ctctggcctt
    55441 atggcaagtc ttggggagaa ggcgggggag aatttgatcg attggctgct tttttgaagt
    55501 ctggtatcca agctgttcga gacactcaac ctaaaacaac tccagtaatg ctccacttag
    55561 ctgatggtgg cgatacagga gcatttactt ggtggtttga tgaaatcacg agtcgaggtg
    55621 tgtcatttga tttaattgga gtgtcgtatt atccgtattg gcacggttca atgaatgaac
    55681 ttcaaaccaa tatgaatgcg atcagccaac ggtatggtaa agaagtgatc gtagttgaaa
    55741 cagcttatgg gcatacaaca gcgaatgccg atactatgcc aaatgctttt ggtgaagccg
    55801 aagcagctgc ggggggatat gaaccaacac cgacaggaca agcagagtat ttgctggatc
    55861 ttgccgatcg gattcaggca gtaccgaata atcgcggggc gggcttcttc tattgggaac
    55921 ctctttggta caacggaaat gtgagttggg caacacaagc aggtatgaat tatctcagtg
    55981 ttcaatccac tatgggaaac gaatgggaca accaagcgat gtttgatttt gctggaaacg
    56041 ccttgccaag cttgcgtgcg tttaaacaag caggggcgca aataaatcta gttaaaaatg
    56101 caagtttcga aagcgatgga ccaacgacca gtccttccaa ttggcaaacc tggtttcaac
    56161 aaggaaccgc taagggtacg atcaaaacgg aagcgggcac tttttttggg gactacaaac
    56221 taactttttg gcaggatcaa gcatacgagg catcagctta tcaaaatgtt agtggcataa
    56281 gcaaaggaac ttacacattg agtgcctatg taatgtctgg gggagagttt gatactaatc
    56341 agttatatat caaaaattat ggtggagcgg aactaaatac tgcggttgtt aaaacaagtg
    56401 aatggacaaa aattacaatc aaagacattc caattacaac aggtgtttgt gaaattgggg
    56461 tttatagcaa ggcttcagga aatgcttgga cgaacgttga ttttgtttca ttggtgaaac
    56521 aatagactgc ggatcgtttc gattcaagat cggaggttcc cttcagccac atcgttagcg
    56581 tagaaggcag gaatcgaacc tgcacctcgc ctttgccaaa aataaccaga aacgatttcc
    56641 agtcattttt accaaaacga gtaaagcacc agacttcatc tacactttgt attatgctaa
    56701 agagagttca acgatttcgt aagaagcaat gaaaaaattg caaaaagttg tgcagataac
    56761 ataaagtttg tttaagaaag ggtaacctta gaattccgtc gtgaatatga tttgagcact
    56821 tagatggata gaaaaaagtt ctcggaaaac agttcgtttt tcgagaactt ctttttatga
    56881 taagaatgaa acaaattaac ttatattata gtctcttttg gtagggaacc atcttatttt
    56941 taatgaaaat caagcatttt agctattgaa gaatgttgat ttatagggat tccccctcca
    57001 tattatgttg gctctttatt cccactccac tgttgctggt ggtttagaag tgatgtcata
    57061 cacgatacgg ttgacgtggg ctacttcgtt tacgatacgt acagagattt tttgcaagac
    57121 ttcccatggg atacgggcaa agtcagcggt cattccgtcg attgaagtta cagcacggat
    57181 accgactgtg tagtcgtaag tacgtccgtc acccataaca ccgacagagc ggatccctgg
    57241 aagaacagtg aaatattgcc agatatcacg gtcaagtcca gcagctgcga tttcttcacg
    57301 caagatagca tcagattcgc gtacgatttc tagcttgtct tcagtgattt cgccaagaac
    57361 acgaatacca agaccaggac cagggaatgg ctgacgccaa acgattgaat caggcatgcc
    57421 taactgagtc cctaattcac ggacttcgtc tttgaataat gtgtttaatg gttcgatcaa
    57481 ttcaaattgc atatcttctg gcagtccacc tacattatgg tgagatttga tcgtctgtgc
    57541 tgtttctgta ccagattcga taacgtcagt atacaacgtt ccttgtgcta ggaaagagac
    57601 gccttcttca ccagcaagtt ttgttgcttc gtcatcaaaa acatatacga attcattccc
    57661 aatgatttta cgtttttgtt ctgggtcaga tacacctttc aacttgtcta agaagcgatc
    57721 tcttgcattg actttgatga tgttcaagcc gaattttccg cctagacttt ccattacttg
    57781 ttccgcttcg cctttgcgta gcagaccgtg gtcaacaaag atagatgtca attggtcacc
    57841 gatcgctttt tgtaaaagaa ccccaacgac actagaatca acgccacctg aaagaccaag
    57901 caagactttt ttgtcaccaa cttgttcacg gattttttct acttgcatat cgataaagtt
    57961 atccattgtc cagttacctt cacagtgaca aacatcaaag gcaaagtggc gcagcaattc
    58021 gattccgtat tcggaatgac gtacttctgc atggaattgg ataccataaa aattacgtgt
    58081 tgtgtcttgg atagaagcaa tcggacaatc tttgcttgtt ccgactgttt caaagccttc
    58141 aggaacttta gttaccaagt caccatggct catccatact gtttgttgtt ttggtgtttc
    58201 tttaaacaag acagcttgat cgcttgttac ttctaacaag gctttcccat attcgcggtt
    58261 tttagcaggc tctacggaac cgccaagttt gtacgtgatc aattgcatac catagcaaat
    58321 ccctaataca ggaataccta aattgaagat ctcaggatcg atcccaaatg cattctcatc
    58381 atatacactg tttggtccgc cagaaagaat gattcccttt ggattcatcg cttttacttc
    58441 ttctgcagta atgcggtggc tcaataattc ggaaaagact ccaagatcac gaatacgtct
    58501 tgtgatcaat tggttatact gactaccgta gtctaatacg ataatctttt caacgttcgt
    58561 catatcggca acgtttgtca aatttattac ccctatccct ttaaatttta tctcaaaata
    58621 gtcaaactat tttaaaatgc taatattttc gcatgaaaat cgaatcgatg atatgatttt
    58681 cagttttatg gagaattata tcggctcttc ctcgtgtagg caagatatat tcctgtaaat
    58741 ttttcaaatt cacatttttc catacatctt ttgccatttt aaaggcttct tcacgatctc
    58801 cgatagcaaa acgataataa taattctctg gattttggaa agccgtatcc agtaacgcac
    58861 caaaacgatc caaataccat ttttcgatca gcacgggatc ggcatcgaca tagacagaaa
    58921 aatcaaaaaa gtcgctgacg tagatttgct gattcgcagg taattgaagc gtattgatcc
    58981 cctcaacgat caagatatca ggctgctgga tcaattcgta cttgtctgga atgatatcat
    59041 acacatcatg tgagtaaaca ggtactttta tctcttcctg accagatttt acacggttca
    59101 agaaatcgat cagcatctcc atatcataac tttcaggaaa tcctttacgg tccatgattc
    59161 cacgctcttt taatatacga tttggataaa gaaatccgtc agtcgtgatc agctgaacgt
    59221 ttcttcgttt gaaggtacga gacaaaatcg tctgcagcag tctggctgtt gtactttttc
    59281 caacggctac acttccggcg atcccgataa taaaaggcgg tacttctacg tatttatgaa
    59341 gaaataaacc tttactcaag aacaaagatt caaattcttt catataaaga taaatcagat
    59401 gagcaagagg tacatagata tctcgaacat cctgcatgga aatgcggtca ttcaaacttt
    59461 tgatattatc tagttcatct tgtgtcaaag gtgcttgccc attacgataa aattctcgcc
    59521 attcttctct tgccacacgg tagtagttca ttggatcatt catattagcc tcctgcgttc
    59581 tcccatcaat ggaactattt taacacaaaa taaacgcaaa ccccaccact taagagagat
    59641 tgccgatctt tttgtataat ctttataata gaaagaaacg gagtcttatt cttgacttgc
    59701 gcacggatac ataaaaggat agactgttgt catgaaagaa atgagaagga tggaagacat
    59761 gacaaatcat tactattctg aacgcccaga tacggcgcac gattttgaac aatgggcttt
    59821 tgagttaaaa ggcagaacct ttcaatttgt aacagattct ggtgtatttt cacgtgaaac
    59881 agtggattat ggttcacgtg tcctgattga tgctttcgat tgggaagagt tacctgatga
    59941 aggaaagatc ttagatgtgg gatgcgggta tggaccgatt gggttagctt tggcatttgc
    60001 gacacagcgg tttgttgaaa tggtcgacat taatgaacga gcggtaagtc tagcgcaagg
    60061 aaacgcaaag cgtaaccaaa tcgaacatgt tgatatccat caatcgaata tctatgaagc
    60121 agttcatgaa gaaacctatg cagctatcgt aagcaatccg ccgatccgtg ctggaaaaaa
    60181 agttgtacat gaaattttga caggcgcata tcctcggttg aagaagggcg gtacactgac
    60241 aattgtgatc cagaagaaac aaggagcgcc gagtgcgcaa aagaaaatgg aagaaacatt
    60301 tggtaatgca gaaatcgtca caaaagataa aggatattat atcatcaaaa gtgtgaaaga
    60361 ataactagct gaaaaatagt ggagcgacga aagagtggaa ctgggcgtgc atgtacgggt
    60421 acgtatcagt tctttttttg ttgagaagtt tttaaaaaca aagaactatt ttttcttcaa
    60481 aaagaaatag taggaacaga gtcgttgttt tttacgataa aataaataag atacagaact
    60541 tgtatagaag gctgccaagt cggtagataa aggaggtttt tatcaaaaaa catactttcc
    60601 ttttttctct attcttttct tgggggtttt ggtacactga tagggaattt agatagaagg
    60661 gagccaatag gatgaagctg accatcagag atatcgcaga aatggcaggc gtatcagtaa
    60721 caactgtctc acagattttg aataacaaag gaagcagatt tagtgataag acaagaaaaa
    60781 aagtgttgtc gatcgtgaat gaacatcatt ataagcccga ttatttcgct tcaaatgtga
    60841 tcaatcgaca ttcaaagacc atcggaatga tcgtccctga tgtcactgat ttcttcttct
    60901 ccaaactgat cgaaggtgta gagagctatt tgaatccttt gggctatgtg atcatgttat
    60961 gcaattctcg tcatagccaa gaaaatgaga tcaagtattt acaagagctt tcccaccgct
    61021 cagtggacgg aatcttgctg gccacaccaa atattttacc tgagaaatat gcattagaca
    61081 gcggttttta tcaaaaaatg ccaatcattt taatcgatcg cggattgaat cgtcgggata
    61141 acggacggct tatcgtaaag gaatatgagg gcgcctatca agctgtttcg ctgtttattg
    61201 aaaatggcca tacgaagatc ggcatgctga aggaaaccac tggatactat caattagaag
    61261 aacgtttcaa cggatatcgt catgcgctga aagatcatgg cctgcctttt aatgggaaat
    61321 ttgttgaaca tggagagttg actgtccaag gtggatatac tgcatcaaaa aaattactca
    61381 aacataaaga tatcacggct attttttgcg ggaatgatgc catggcgatc ggatgctatc
    61441 aggcgatcga tgaattgggc aaaaaaatcc cagaagatat ctcagtcata ggattcgatg
    61501 gattaaagct gtcagaatac atgattccgc aattgacgac agtgcagcag ccaagttttg
    61561 atattggatt ttatgctgca cgtttcctga tcgatacgat cgaatttcct caaagaaaag
    61621 ttccgaacaa agtgttcgaa acaaaattaa ttattcgtga gagcgtaaaa gtattgacaa
    61681 agggctaact cggcggtata ttgcttatgt aagcatttac aaaggctagt tagtgctttt
    61741 tttattttta gtaaaccagt ttactaaagt ggtttacctt tcctaaaaat aatgtataat
    61801 accgaatgaa gacaaggagg atcaggcaat gcgaatggtg gatctgattg aaaaaaagag
    61861 ggatggaaac gagctgtcga aagaggaaat cgagtacatc gtcacgaact atacgaatgg
    61921 aaagattcca gattatcaag tcagtgcatt attgatggca attttttatc aagacatgac
    61981 aaatgaagaa atcacgaact taacattggc gattgctaat tctggtgatg tcatcgattt
    62041 gagttctctt gaaggaataa aggtagataa gcattcgaca ggtggcgttg gtgacacgac
    62101 cacattgatt ttagcccccc tagtagctag tgtcggagtg acagtggcta aaatgtctgg
    62161 acgcggtcta ggttacacag gtggtacact agacaagcta gaagcaattc ccggatttca
    62221 gatcgagctt tcggatgaag aatttgtacg cattgttaat gaaagtaaag tagcggtaat
    62281 tggtcaatca ggaaacttgg caccggcgga caaaaaattg tatgccttgc gtgacgtcac
    62341 agcgaccgtt gattctcttc cgctgattgc cagttcgatt atgagtaaaa aaatcgcggc
    62401 aggagcagat gcaatcgttt tggatgtgac cactggagac ggtgctttca tgaagaacat
    62461 cgaagatgca agacgtctgg caaagaccat gacgagcatt gggaaactgg ctaaccgaga
    62521 aacagtggcg gttatctcag atatgtcaga acctcttggc gaagctatcg gaaatagtct
    62581 agaagttgtc gaggcaatcg aaacattaca aggaaatggt ccagaagatc tagtagaaat
    62641 gtgctacgcc ttaggaagcc aaatggttgt tcttgctggc aaagctaaga caaccgatga
    62701 agcaagaacg ttgcttcaag aagctctgga atcaggtaaa gcgttagcaa aattcaaaga
    62761 aatgatccaa aatcaagggg gagacccagc gatcgtggaa catccagaac gaattttgac
    62821 tgcacgctac acaatggagc ttcctgctaa acaaagcgga gttgtgtcaa aaatcgtggc
    62881 aaatgaatta ggaattgctg caatgatgct aggtgctggg cgtaaaacca aagaagaaga
    62941 tattgatcac gctgttggat tgaaactgca taaaaaaatt ggtgacactg tgacaaaagg
    63001 tgagtcacta ttgacgatct atagtaacga cgaagaaatc acttctgtca ttgaattatt
    63061 atataaaaat attgaaattg gtgaatcggc aatgaagcca acgttgattc atgacatcat
    63121 cacagaataa aggaaaaaag cggactttac cgttttaaag aaaaggggaa aagaaatgga
    63181 actaaaccga atgatcgacc atactatttt gaaagcagac gcatctaaag aagctgtgat
    63241 gcaaattatc gaagaagcaa aaaaatacca tttttattct gtctgcatca atccagcatg
    63301 ggttgcgcta gcgaaagaac aattacaagg tgagccagta gccgtatgta cagtaatcgg
    63361 gtttcctcta ggagcaaaca cacccgagac aaaagcattt gaaacaacag atgccatcaa
    63421 taacggtgca gatgaagtcg atatggtcat caatatcggt gctttgaaat caaaggatga
    63481 tcaacaagtc caaaaagata tcgaagcagt tgttgaagca gcaaaagatc gtgcgcttgt
    63541 caaagttatt attgaaacat cgttattaga tagagaagaa atcatccgag cttgcgaaat
    63601 agcaaaagct gcaggcgctg attttgtcaa aacatcaact ggtttctcaa caggcggagc
    63661 aaaggtagag gatgtccgtt tgatgcgtga aactgtagga ccagaaatgg gtgtcaaagc
    63721 ttccggcggt atccataacg aagaagaagc aatggcaatg atcgaagctg gtgctacaag
    63781 aatcggaaca agcgcaggag tagcaatcgt atctggttca actggtgaag gctattaatt
    63841 ttttcaaagg agaagctcat ggcagaactc aaacaagaat ggatcaacac agctattgaa
    63901 gcgttagata aagcctatgt tccttattcc cattttccgg taggcgcttg tctcgtaacg
    63961 gaatcaggca agatttatca aggcatcaac attgagaatg catcatttgg attaacgaat
    64021 tgtgccgagc gcacagcttt tttcaaagca gtatctgaag gagaaaaaac atttacgcat
    64081 ctagtcgtag cggggcacac ccccgatcct atctctcctt gtggtgcatg tcgacaagta
    64141 atggcagaat tctgttcccc tgatatgccg gttacgctag taggagacaa tggtgtgacg
    64201 aaggcaacga ccgttcgtgc actgctgcct tatgcattta ctgaaaaaga tctataactc
    64261 atgttcattc agtcagctga ctgttgaaaa ataaaacaat tattttagga ggctttacag
    64321 aaatgaaaaa agcaaaatta tttggtttag gtgctgtcgc actagcagca gggttatttt
    64381 taggtgcatg cggcaacaac ggctctactg attcatccgg tggcaaaagc tcatcagaca
    64441 caacaactgc agcattgatc acagacacag gtggtgtaga cgaccgttca ttcaaccagt
    64501 cagcttggga aggactagaa aaatggggga aagatcaagg actttcacga ggaaatgatg
    64561 gcttccaata tttccaatct tcaaatgaat cagattacat cccaaatatt gaccaagcat
    64621 tgaatgctgg attcaaaacg atttttggta ttggttataa actaaaacca gcgatccaag
    64681 aacaagcaac aaacaataca ggtacgaact ttgttattat cgatgatgtc atcgatggat
    64741 tagataacgt tgtatctgca actttcaaag acaacgaagc ttcttatctt gcaggtgttg
    64801 cagcagctta tacgactgaa acaaacgtag tcggctttat cggcggtgta aaaggtgaag
    64861 taatcgatcg ttttgatgct ggattcaaag ccggtgttga tgcaggtgcg aaagaattag
    64921 gaaaagaaat caaagtattg aatcaatatg ctggtgactt ctctgctcca gataaaggac
    64981 gttcaattgc tcaaggtatg tatgcacaaa acgcagatat catcttccat gcttcaggcg
    65041 gtacaggtaa cggtgtattc caagaagcaa aatcattgaa cgaatcaggc gacaaaaaag
    65101 tttgggttat cggtgttgac cgcgaccaat cagacgaagg cgaatacaca ttaaacggcg
    65161 aaaagaaaaa cttcacattg acatctacac tgaaagcagt tggaacagta gtagaagatt
    65221 tggcacaaaa atcagcggac ggtaaattcc ctggcggcga acacactgtt tatggattga
    65281 aagaagacgg tgttggtcta acagaaggac aactttctga cgaagcgaaa aaagcagttg
    65341 atgaagcaaa agaaaaaatc atttcaggtg acgtaaaagt tccagaaact cctgaagaaa
    65401 actaaaacca tttctatagc cttgttagac acatgtttga caaggctatg gtttgattag
    65461 aacaagaatt gttcatttat ccaagctgcc ttgtgacagt ttggataagg gaacaactcc
    65521 ctgaagtaat gtttgtttca aaagaagaac gctcactaag cgtgaatctt agtcaatcgt
    65581 tgccctagat agaaatcgtt aggatgtgaa aaaaaggtgg ttcaagaaaa tattgtcata
    65641 gaaatgcaga atattaccaa agaatttgga acattcaagg caaatgacaa catcaattta
    65701 caagtaaagg caggagaaat tcatgcgttg cttggagaaa acggtgctgg caaatctaca
    65761 ttgatgaacg tgctttccgg attattagag ccgacatcag ggaaaatttt gatgcgtggg
    65821 aaagaagtaa agatcacaag tccgaccaaa gccaaccaat tagggattgg gatggtccat
    65881 cagcacttta tgcttgttga tgcctttact gtaacagaaa acatcgtgtt gggaagcgag
    65941 cctagtcgcg cagggatgct tgaccataaa aaagcacgaa aagagatcca aaaagtttct
    66001 gaacagtatg gattgtcagt caacccagat gcttacgttc gtgatatttc agttggaatg
    66061 gaacaacggg tagaaatttt aaaaacactt taccgaggag cagatgtact gatttttgat
    66121 gagccgacag ctgtattgac ccctcaagaa attgatgaat taatcgtgat catgaaggaa
    66181 ttagtcaaag aaggcaagtc gatcattttg attacgcata agttagatga aatcaaagca
    66241 gtagctgacc gctgtacagt tatccgccgt ggaaaaggaa tcggtacagt caacgttaaa
    66301 gacgtaacct cacaacaatt agccgatatg atggttggaa gaacggtttc attcaaaacg
    66361 atgaaaaaag aagcgaagcc tcaagaagtc gttttgtcta ttgaaaatct agtggtgaaa
    66421 gaaaatcgtg gattagaagc cgtgaaaaac ttgaacttag aggttcgtgc tggcgaagta
    66481 cttggtatcg ctggaatcga tggaaacggg cagtcggagt tgatccaagc tttgactggt
    66541 ttgcgaaagg cagaaagcgg acatatcaag ctaaaagggg aagacatcac taataaaaaa
    66601 ccccgaaaaa tcactgaaca tggtgtagga cacgtgccag aagaccgtca taaatacggg
    66661 ttagtcctag atatgacatt atctgaaaat atcgcactac aaacctatca tcaaaaacct
    66721 tacagtaaaa acggcatgct gaattattca gtaatgaatg aacatgccag agaattgatc
    66781 gaagaatatg atgttcgaac aacgaatgaa cttgttcccg caaaagcttt atcaggcgga
    66841 aatcagcaaa aagcaattat cgctcgtgaa gtcgaccgag atcctgatct gttgattgtt
    66901 gcaaatccaa ctcgtggact ggatgtaggt gcgatcgaat ttattcataa acgtctgatc
    66961 gaacaaaggg acaaatacaa agcagtgtta ctgatcagtt tcgaattaga agaaatttta
    67021 aatgtttcgg atcgtattgc tgttatccat gaaggagaaa ttgtcggtat cgttgatccg
    67081 aaagaaacat ctgaaaatga attaggtcta ttgatggcgg gctatacctt agaagaagca
    67141 cgaaaagagt tagaaaaggg ggctggcgca catgaatgat cgcagcgaaa aattccgtaa
    67201 tttattagtg cctgtacttt cagttgtttt aggattgatc ttaggcgcga tattgatggc
    67261 tgcttttggt tttcagccca tccaaggtta ttcttctatg ctagatgcag cccttggttc
    67321 gcaaagaggg ataggtgaaa cgttaaggca agcaacgccg ttgattttta cagcattagg
    67381 tttttctgta gctaactcag ctgggttttt caatattggg ctttctggac aagcactttg
    67441 cgggtggatc gtcagtgtct gggtggcact tgcgtttcca gatctgccaa aagttgtttt
    67501 gcttccgtta tgcgtgatct taggtgcctt agctggtgcg atggcagcgg ctgttccagg
    67561 tttacttcga gcattttttg gaacaagtga agtgatcgta acaatcatga tgaactatat
    67621 cttattatac gtaagcacat ttgctttaca tgaagtgatg cctgaaagct atcgctcaag
    67681 tttggactct tccaatatga tcagtcaaaa tgcctcactg cggttaccat ggttaacaca
    67741 agcttttggc ggctctcgcg taaactcagg attattttta gcaatcatcg cgcttatttt
    67801 cgtttggctg ctgatgaaga aaacgacttt aggatttgaa atccgttctg ttggattgaa
    67861 tccttttgct tctgagtatg caggaatgag tagtaaacgt acgatcgttt tgtcgatggt
    67921 catttctggc gctttggcag ggcttggcgg tgtggttgaa ggattaggaa cgtatcaaaa
    67981 cttctttgtt caaacgactt cgctatctat tggatttgac ggaatggctg tttccttgct
    68041 tggttctgga tcagcaatcg gtattctttt atcagcgatc ttgttcagta ttttgaagat
    68101 cggtggactt ggcatgcaga caggagcagg tgttccgttt gagatcgtca atgtatcgat
    68161 tgctttgatt atcttctttg tcgggatcaa cttcctgatt cgtttcgtca tggctaaagt
    68221 cttccaaggg aaaaaacaag aagagatcgt tgcgacaata gaatcgaaac caacgaatca
    68281 aaaccatgaa gggggcgaac tataatgtcg actatcgaat taattgcctt gatccttact
    68341 tctacactgg tttattcaac accgctaatt ctaacgtcac taggcggaac tttttctgaa
    68401 cgaagcggga tcgtaaacgt agggctagag ggaatcatgg tcatgggtgc ttttagttcc
    68461 atcgttttca acttgacgat gagtccatca cttggttcta tgacaccatg gatcgctatt
    68521 ttagtgggtg gcgtcgtagg tatcctattt tctctgattc acgcagtagc aacagtcagt
    68581 ttgcgtgctg accatattat cagcgggaca gtaattaatc tgatggcacc tgctttaggt
    68641 gttttcttga tcaaagcatg gtatggtaaa ggtcaaactg ataacatcac gcagaatctg
    68701 gggtattttt ctttcccagg attagcagat attccggtca ttggaccaat tttctttaaa
    68761 aatacattct tacctgctta ttgtgctatt ttgattgctg tcctagcttg ggtgatcatc
    68821 ttcaagacga aattcggctt gcgcctccgt tcagttggtg aaaatcctca agctgccgac
    68881 acattaggta tcaatgtata tgctatgcgt tattcaggcg tactgatttc tggcttgtta
    68941 ggcggtatgg gcggtgctgt ttttgctcag tcgatttccg gtaacttttc agctggtacg
    69001 atcgttggac aagggttcat ctccatggct gctatgatct ttggtaagtg gaatccttta
    69061 ggggcaatgg gtgcctcatt gttctttggt tttgctcaaa gcttgagtat cattggcgca
    69121 caattaccag ttatttcttc gattccgcca gtattgctgc aaattgctcc atatttgctg
    69181 acaatcattg tgctggttgt tttcttaggg aaagcttctg gtccaaaagc aaacgggaag
    69241 aactatatca aatcaaaata atcttttagc gaataaaaag ggtgggttac gggaagtgtt
    69301 tttcgtctcg ccctttttgt tttaaaggca ataaaaataa aaagaaagaa ggaataatca
    69361 tgtttaaacg cgtacatctg atcgtcatgg attcagtagg aattggagaa gcaccagatg
    69421 ccgataagtt cggtgatgtt ggttctgata cattaggaca cattgcgaaa gaagcaggat
    69481 tgaacgttcc acatttagag cagcttggtt taggaacgat ccgtcctctt gaaggtgtgg
    69541 aatcagtgaa agatcatcaa ggctatgcga cgaaattaga agaagtttct gtagggaaag
    69601 atacgatgac aggccactgg gaaatcatgg gattgaatat caaaactcca tttcgtgtgt
    69661 ttcctaatgg attccctgat gatctgatca aacaaatcga agaattttct ggccgtaaag
    69721 tcgtatgtaa caaaccttat agcggaacag ctgttattga cgattacggt gaacaccaaa
    69781 tgaaaacagg cgatttaatt gtatatactt ctgccgatcc tgtccttcag atcgcggcac
    69841 atgaagaaat cattccttta gaagaattat atcggatttg ccaattcgtt cgtgatataa
    69901 caaaagatga tccgtatatg attggccgaa tcattgcacg tccgtacgtg ggtgaaccag
    69961 gagacttcac acgaacaagc aatcgccatg attatgcgtt gaatccattc ggacacacag
    70021 tccttgattc tttgaaagaa gcaggaaagg acgtgattgc tgttggaaag atcaacgata
    70081 ttttcaacgg acaaggaatc actgaatctg tccgcacgaa aagcaatatg gatggcgttg
    70141 accagctgct gaaagttatg aaaaacgatt tttcaggaat cagctttacc aatttagtag
    70201 attttgatgc attatacggt catcgtcggg atgtagtcgg ctatgcgcat gcgattgaag
    70261 aatttgactt acgaattcca gaattgcttg aagcgatgga agaagacgac ttgctaatga
    70321 ttacagccga tcacggaaac gatccgacgt ttactggtac cgatcatacg cgagaatatg
    70381 taccgttatt ggtttacagt aaaaaaatga aagaacaagg ggcattgcct caaggatatt
    70441 attcagatat ttcagcaacg attgctgaga actttagtgt ttcttcgact gaaaatggcg
    70501 aaagcttctt gaaattatta aaataatctt tttaaatagg agaaagcaaa tgaccaagtt
    70561 aagcgagatg ttacaagaaa cgacccagtt tatccttgat aaaggagtaa aagaaattga
    70621 ttttggtttg attctaggtt caggattagg tgaattagca gatgaaatcg aagatgctgt
    70681 aatgatttct tatgatgaga tcccgttctt tcctgtttcg acagtagttg ggcatgcagg
    70741 aaagctagtt tatgggtctc tggcaggcaa gaaagtgtta gccatgcaag ggagattcca
    70801 ctactatgaa ggtcattcca tgcaaacagt gacctatcca gtacgtgtga tggccggact
    70861 aggggcccat tcagtcattg tgactaatgc atgtggtggt gtcaacgaat catttgtacc
    70921 aggagatttg atgctgatta ccgatcatat caattttact ggtgaaaatc ctttgatcgg
    70981 tccgaatgaa gatgcaatgg gccctagatt tccagatatg agtcaagctt atacgcctga
    71041 ctatcaagca acagcaaaag cagcagcaga aaaactaggt ttggatctta aagaaggcgt
    71101 atatatgggc tattctggac caacttatga aacgcctgcg gagatccgaa tgtctcggac
    71161 aataggagcc gatgcagtag ggatgtcgac tgttccagaa gtcatcgtag cagctcacag
    71221 cggattaaaa gtgttaggaa tctcttgtat taccaactta gcagcaggta tgcaagcgaa
    71281 tctgagccat gaagaagttg tagaaacaac tcagagagtc aaacaatctt ttaaagcatt
    71341 ggttaaagaa acattgacat tattgtaata ggaggaacaa taaaatgagt gtgcatattg
    71401 aagcgaaaga aggcgagatc gccgataaga ttttacttcc gggagatcct ttgcgagcta
    71461 aatatattgc ggagactttt ttggaagatc cagtttgtta caatcaggta cgcggtatgt
    71521 taggctttac cggcaaatat aaaggagaac gtatttctgt tcaaggaaca ggaatgggaa
    71581 tgccatcagc caccatctat gcccatgaat tgatccagtc gtatggtgta aagaaattga
    71641 ttcgagtagg tacatgcggt gcattgtcaa aagacgtcca tgttcgtgat ttagtactag
    71701 cacaaggtgc agcgaccagt tcttcgatga tcgaaaaaaa tttccaagcc tttcattttc
    71761 ctccaatcag tgatttcaat ctattactga aagcatatga gatagctaaa gaaaagggct
    71821 atacggttca tgtaggaaat gttctttcgg aagattcttt ctacaaagat gatttgacag
    71881 agacgttcca attagctgaa cttggcgttt taggagtgga aatggaagca gcggctcttt
    71941 attacttagg cgcgaaatac catgtgcaga cattaagttt gatgaccgtt agcgaccatt
    72001 tgatcaccgg tgaagaaaca acagctgcag aacgtcaatc tacgttcaat gaaatgatcg
    72061 aagtaggatt ggaaacagcg atagcagaat aagaaggaaa tgaaaaagct gccctgcatt
    72121 aagtaataag aacatccaag caaaaatagc tcctcatgtt tttgacttgg ctggacttat
    72181 tattgcaaat gtaagctttt gaacaccgtt taccaagagg ttgtgaatct gccgtttaac
    72241 tctgagtcac aaggaacaat ttcaaaaaac agcttttcat gtttgatgaa tattgtgact
    72301 tgtgaccgag aagttggcag gagaaaaccg tttatacgaa aaaagggact gtgacaaatc
    72361 gtgtcacagt ccctttttta tagtgttttt tataggtagt attttttagc aactgttaag
    72421 tcatcattta attcataaac aagtggttga cctgttggaa tttcaagatc catgatgtct
    72481 tcgtcagaga taccttcgat atgtttagct agggcgcgta atgagttacc atgtgcagct
    72541 actaaaacag ttttgttgtc tagtaatgct ggagcaattt catcttgcca gaatggcaaa
    72601 gcgcgttcta atgtcacttt caagttttct ccaccaggaa tatcgcgttt gtctaacatt
    72661 gcgtaacgac ggtcatttgc tgcagaacct tcgtcagttt cttccattaa tggaggaaga
    72721 gtatcgtaag aacgacgcca gatgtgcact tgttcgtcgc cgtatttttc agctgtttct
    72781 tttttgttca aaccttgtaa tttaccatag tgacgttcgt ttaagcgcca tgatttgatt
    72841 tgtggtaccc aaagttgatc tgaatattct aagatcaagt tacatgtttt gattgcacga
    72901 gttaaaacag aagtgtaagc aacatcaaat tcgattccag cttctttgat tttgcgtccg
    72961 ccttcttttg cttcttcgat tccttctggt gctagattta catcagccca accagtaaat
    73021 tggttcaatg cattccattc actaagaccg tgacgagaaa aaactaattt tggcatgttt
    73081 agctctcctt ttaagatagg tttatatttc tgaaattttc agttctgttt tattgtacaa
    73141 ttttttggaa gagatttcca tcgaaaaatt agataagatt ctatgagaaa acaagtagag
    73201 aatataaaaa aacgaacagt gcccacgcaa ctgttcgttt ttaggtatta gatgcataat
    73261 tgctcgattt ctttttcagg taaattgata tatttataac atgttccaac tgaaacaccg
    73321 cattttgaag aaataaattg gatcgtttct tttttttcat aatagagacg tcggattttt
    73381 ttgatcgttt ttgcatcgat ttttggtctt ccgccgattt ttcctttttt acgagcttca
    73441 tctaatccaa ctaatgtacg ttctttgatc aatgcgcact ccatgtttgc taggttttcc
    73501 attaattgga aatagatttt tcccatttcg cgcgtatcga ttccttcatc aagactaatc
    73561 aagtgcagcc cgcgatcttt gaataattgc gtgagttctg ttaattgccg cgtagatttg
    73621 cctaatcgat gaagttggca aatgactagt gcatcgcctt gttgcatgtc agcgatcact
    73681 gactccaaat gaacagcagt agaatcattt tgttccactt catatgtctc atggaaaatt
    73741 tcttgacaac caaagtcaga taattgatca acctgagttg ttaaatcaac gtcatttatg
    73801 gttgtgcgtg cataaccaat aattttcatg gtgattcctt tctagcagtg attttctaac
    73861 tggatataac agtaaaaatg tagcataaag tacgtcaaaa agatagtttt ttcgcaaatt
    73921 ttccgctgtc tttttttatt ggatgatcaa gcagtttttc tttatttacg acggattgcg
    73981 tcaagaatct caacgccttt ttctgagccg acaactactt tagaaaccat gtttaggaaa
    74041 agcccatgtt ctactacccc aacaagttca tctaaatagg tagctaagct ttctggctgt
    74101 tcgatgactt ctagatgcag atcaatgatg taatgaccac catctgtggt taagacttct
    74161 ccgttttcgt ctgtacgcaa gacgggttgg aatctttttt cttcaaaaat atgaagtagc
    74221 tgttgggagc cataagggat cacttcaact gggagtggga acttcccaag tttatcgact
    74281 aatttagaag aatcaacgat ccaaatcgtt tcttttgagt acgtagcgac tattttctcg
    74341 aaaagcaaag cagcgccgcc gcctttgatc ccttgaaaat cagcactgat ttcatcagca
    74401 ccgtctattg tcaaatcgac tacggggact tcatcaatac tctttaacgg tattcctaat
    74461 ttttccgctt gttcttttgt cgcatttgaa gtagtaactc ctgtgatacg taaaccttct
    74521 tcacgcatac ggcgaccaat ctcttctacc atataatagg cggttgaacc ggtcccgaga
    74581 cctacgatca tcccgtcctt tacgaatttc gcggcttcaa tgccagctaa ttgttttaaa
    74641 ttcatctttg cgtccacctt tttttagttt gagcatcgtg ctttcctcac tattttagcg
    74701 tgatttacgg taaaaagata ccattctttt ttattccaat aaagcttttt caaaaaaaat
    74761 tgcatctctt gttgacatgt tttttcattc gtgatattct aacaaaggtg ctttatctac
    74821 aggtttctgt gaagaaacgt gctgactgtt tatcaaagca tatttgataa ggatgcagac
    74881 attgcattta ttttttatca caaaaaaaga accacctgga tgtgtggaac tagacgcaaa
    74941 tcgtgggaag gaggaaacaa ggaatgccta caattaacca attagtacgt aaacctcgta
    75001 aatcaaaggt ggaaaaatct aattcacctg ctttgaacaa aggatataac agctttaaga
    75061 aaactcaaac taacgtaaac tcacctcaaa aacgtggggt agcaactcgt gtgggtacaa
    75121 tgacacctaa aaaaccgaac tcagctttac gtaaatatgc acgtgttcgt ttgtcaaact
    75181 taattgaagt tactgcttat atcccaggga ttggtcataa cttacaagaa cacagtgttg
    75241 tattattacg cggtggtcgt gtaaaagact taccaggggt acgttaccat atcgttcgcg
    75301 gtgctttaga tactgctggt gttaacgacc gtaaacaaag ccgttctaaa tacggaacta
    75361 aaaaacctaa agcttaattt taattattaa acaaatgaaa cttgcttcta ctatatagaa
    75421 gtaattacta tgaacaatat ttcggaagga ggagttacgg atgccacgta aaggtcctgt
    75481 tgcaaaacgt gatgttttac cagatcctat ttataactca aaattagtaa ctcgcttgat
    75541 caaccgtgta atggttgacg gaaaacgcgg gattgcagct aacattatct ataatgcctt
    75601 tgacttgatc aaagaatcta caggtaacga tccattagaa gtgtttgaac aagcaatgaa
    75661 aaacgttcaa cctgttcttg aagttaaagc acgtcgtgtt gggggttcaa actaccaagt
    75721 accagttgaa gttcgccctg aacgccgcgt tactctaggt cttcgttggg tagtaaacta
    75781 cgctcgcttg cgcggtgaac acacaatgga agaacgctta gcaaaagaaa tcatggatgc
    75841 tgcaaacaac acaggtgctt ctgttaaaaa acgtgaagac actcataaaa tggctgatgc
    75901 caaccgtgcg tttgctcact atcgctggta agattctctc tgtttggtcg gcttttataa
    75961 gtcgacctca gatagtgtcc ttatttttag caactagata gtaaagagag gagaaacaag
    76021 gagaatgacc agagaatttt ctttacaaaa cactcgtaat atcggtatca tggcccacat
    76081 cgatgctggt aaaacgactg ctactgaacg tatcttgtac tatactggta aaatccataa
    76141 aattggtgaa actcatgaag gagcttcaca aatggactgg atggaacaag aacaagaacg
    76201 tggtattacg atcacttctg ctgctactac agcacaatgg aagggtcacc gaatcaacat
    76261 catcgacaca ccaggacacg tagacttcac agttgaagtt gaacgttcat tgcgtgtact
    76321 tgatggtgct gtaactgttc ttgatgcaca atcaggtgtt gaacctcaaa ctgaaacagt
    76381 ttggcgtcaa gcaacaactt atggtgtacc tcgtatcgta tttgcaaaca aaatggacaa
    76441 gatcggtgct gacttcttat attcagtatc aactttacat gaccgtttgc aagcaaacgc
    76501 tcacccaatc caattaccaa ttggtgcgga agacgacttc acaggaatta tcgaccttgt
    76561 aacaatgaag gctgaaatgt atacaaacga tcttggaaca gagatcgaag aaacagaaat
    76621 tcctgaagaa taccgcgaat tagctgaaga atggcgcgaa aaattggttg aagctgtagc
    76681 tgaaactgat gaagaactta ctttgaaata cttagaaggt gaagaaatca ctgaagctga
    76741 gttaaaagaa ggtatccgcc gcgcaacagt taacgtagaa ttctacccag tactatgtgg
    76801 ttcagcattt aagaacaaag gggttcaatt actattggac gctgttcttg attacttgcc
    76861 atcaccgtta gatatcccag ctatcaaagg gattgaccct aaaactgatg aagaagtaga
    76921 acgtcctgca gacgacagcg ctcctttctc agctttagca tttaaagtta tgactgaccc
    76981 attcgtaggt cgtttaactt tcttccgtgt gtactctggt gttttacaat caggttcata
    77041 cgtacaaaac gcaacaaaag gcaaacgtga acgtgttggt cgtatcctac agatgcatgc
    77101 caactctcgt tcagaaatct ctgaagttta cgctggagat atcgctgctg ctgttggttt
    77161 gaaagacaca actactgggg acacactatg tgatgaaaag agtctagtta ttcttgaatc
    77221 catggaattc ccagaaccag ttatccaagt cgctattgaa cctaaatcaa aagctgacca
    77281 agataaaatg ggtgtggctt tacaaaaact atctgaagaa gatcctactt tccgtgctga
    77341 aacaaacgtg gaaacaggcg aaacaatcat cgctggtatg ggtgaacttc acttagatat
    77401 catcgttgac cgtatgcgtc gtgaattcaa agttgaagct aacgtaggtg cgcctcaagt
    77461 atcttaccgt gaaactttcc gtgctggcac tcaagccgaa ggtaagtttg tacgtcagtc
    77521 tggtggtaaa ggtcaatacg gtcacgtatg gattgaattt acaccaaatg aagaaggtgc
    77581 tggtttcgaa tttgaaaatg cgatcgtcgg tggggttgtt cctcgtgaat acattccagc
    77641 tgttgaaact ggtttgaaag atgctatgga aaatggtgtc ttagctggct atccattagt
    77701 agatatcaaa gctaaacttt acgatggttc ataccatgat gtcgattcaa atgaaactgc
    77761 cttccgtgtt gctgcttcta tggcattacg tgcagcagct aagaaagcta atccagtaat
    77821 ccttgaacca atcatggctg tagaagttgt tatccctgaa gattatttag gtgatgttat
    77881 gggtcacgta actgctcgtc gtggacgtgt tgaaggtatg gaagctcgcg ctggcggcca
    77941 acaagttgtt cgtgcgatgg ttccacttgc tgaaatgttt ggttatgcta caactcttcg
    78001 ttctgctact caaggtcgtg gtacatttac aatgacattt gaccactacg aagatgtacc
    78061 aaaatcagta caagaagaaa tcattaagaa aaacggcgga aaagctgaat aatttcttaa
    78121 aaccggatag tcctgcaaag agattatcca aagagactat atttttaata tagtttcgtg
    78181 taaaataatt atcgatgata tgggcatgtg gtgtaccttg tgtacatcat atacctatca
    78241 gacaaataaa aaatatattg tatttttagg aggacatttt aaaatggcaa aagaaaaatt
    78301 tgaccgttct aaaccacacg ttaacattgg tactatcgga cacgttgacc atggtaaaac
    78361 tacattaaca gctgcaatca caactgtact atctaagaaa aacggcggcc aagctatggc
    78421 ttacgatcaa atcgatggtg ctccagaaga acgcgaacgc ggaatcacaa tctcaacagc
    78481 tcacgttgag tatgaaacag atacacgcca ctacgctcac gttgactgcc caggacacgc
    78541 ggattacgtt aaaaacatga tcactggtgc tgctcaaatg gacggagcta tcttggtagt
    78601 ttctgctgct gacggcccaa tgcctcaaac tcgtgaacac atcctattgt ctcgtcaagt
    78661 tggtgttcct tacatcgttg tattcttgaa caaagtagac atggttgatg acgaagaatt
    78721 actagaatta gttgaaatgg aagttcgtga cctattaaca gaatacgaat tccctggtga
    78781 cgatgttcct gtagttgctg gatcagcttt gaaagctcta gaaggcgacg cttcatacga
    78841 agaaaaaatt cttgaattaa tggctgcagt tgacgaatac atcccaactc cagaacgtga
    78901 caacgacaaa ccattcatga tgccagttga agacgtgttc tcaattactg gacgtggtac
    78961 tgttgctaca ggtcgtgttg aacgtggaca agttcgcgtt ggtgacgaag ttgaagttgt
    79021 tggtattgct gaagaaactt caaaaacaac agttactggt gttgaaatgt tccgtaaatt
    79081 gttagactac gctgaagctg gagacaacat tggtgcttta ctacgtggtg ttgcacgtga
    79141 agacatccaa cgtggacaag ttttagctaa accaggtaca atcacacctc atacaaaatt
    79201 ctctgcagaa gtatacgtgt tgacaaaaga agaaggtgga cgtcatactc cattcttcac
    79261 taactaccgt ccacaattct acttccgtac aactgacgta acaggtgttg ttgaattacc
    79321 agaaggaact gaaatggtta tgcctggcga caacgtaaca atggaagttg aattaatcca
    79381 cccaatcgct atcgaaaacg gtactaaatt ctcaatccgt gaaggcggac gtacagttgg
    79441 tgccggtgtc gttacagaaa tcaaagctta attcacttaa gttttaaagt aaagcaacat
    79501 ttattcggac gtaatcgctc ggaacgaagg tcttaggatc tttgttccga gcttttttat
    79561 ttattgcagg atcaggaaaa aagacaggag tattataaat agaagaaaca cgaaataaaa
    79621 gagtcagtat tttctaaatg aaactttatg aaaacaaaat gttttttaca agaaaaagcc
    79681 ttgctttgtg agtttatata tattataatg acaaaggtgc gtttacttta gtgaattgca
    79741 cagacgtaat cagaatgatt tcgtcggcta agaaacgaga ggttgcgaca cgcccggacg
    79801 ctttgccacg aacgagcgtg acggaaattt tcgtggagct atgtctactt ttcaaaatag
    79861 gcgaaggagg gaacaagatg gcaaaacaaa aaattcgtat ccgtttaaaa gcgtatgaac
    79921 accgtatttt agatcaatca gcggataaaa tcgtggaaac tgcaaaaaga actggagcta
    79981 gcgtgtctgg tccaattcca ttaccaactg aacgcagtct ttacacaatc atccgtgcga
    80041 ctcataaata caaagattca cgcgaacaat tcgaaatgcg tacacacaaa cgtcttatcg
    80101 acattgtgaa cccaacacca aaaactgttg atgctttgat gaagctagac ttaccatctg
    80161 gtgtaaacat cgaaatcaaa ttataaaact aaaacaaaaa taatggaggt gtactcatga
    80221 ccaaaggaat cttagggaaa aaagtgggaa tgacacaaat cttcactgaa tctggtgaat
    80281 taattccagt aactgttgta gaagctactc caaacgtagt actacaagtg aaaacaatgg
    80341 aaacggatgg ctacgaagct attcaagttg gttaccaaga tatgcgtgaa gttttatcaa
    80401 acaaacctgc gaaaggtcat gttgcaaaag caaacacggc tcctaagcgc ttcattcgtg
    80461 aattcaaaaa tgttgagcta ggagaatatg aagtaggaaa agaaattaca gtagatgttt
    80521 tccaagcagg agacattatt gatgtaacag gtactacgaa aggtaaagga ttccaagggg
    80581 ttatcaaacg ccacggacaa agccgcggac caatggctca cggttctcgt taccatcgtc
    80641 gtcctgggtc aatgggtcca gttgcaccta accgtgtatt taaaaacaaa cgtcttgctg
    80701 gccgtatggg tggcaaccgc gtaactatcc aaaacttgga agttgtacgt gtcgatgcag
    80761 aaagaaatgt tatcttgatc aaaggtaatg ttcctggagc taaaaaatct ttaattacta
    80821 tcaaatcagc tgtgaaagct aaataattgt aggaagaaag gaggaactaa ggaatgccga
    80881 atgtagcatt attcaaacaa gatggaagcc aaaacggtga aatcacactt aacgaagaaa
    80941 tcttcggaat tgaacctaat gaaagtgttg tttacgatgc aatcgtaatg caacgtgcgt
    81001 cattaagaca aggaacacac gcggttaaaa accgtagcgc tgttcgcggc ggcggacgta
    81061 aaccatggcg tcaaaaagga acaggtcgtg cacgtcaagg atctatccgc tcaccacaat
    81121 ggcgtggagg tggcgtagtc tttggaccaa caccacgttc ttacagctac aaacttccta
    81181 aaaaagttcg tcgtttagca atgaaatctg tattgtcaga aaaagttgct gaaaacaact
    81241 tggtagcaat cgaaggcttg aacttcgacg caccaaaaac aaaagaattc aaacaagttc
    81301 ttgctaactt atctatcgac tctaaagtat tggttgttct agaaaaaggt aacgactttg
    81361 ctgctttatc agcacgtaac ttaccaaacg tttctgtagt aacttctgat aatgtgagtg
    81421 tgctagacgt tgtatcaaat acaaaagtgt tagcaacaca aactgctctt actcaaattg
    81481 aggaggtgct tgcataatga acttactaga cgtaatcaaa cgcccagtga tcactgaaaa
    81541 atcaatgctt gccatggatg acaagaaata cacttttgaa gtggacactc gcgcaaacaa
    81601 aactttagta aaacaagcgg tagaagctgc ttttgacgtt aaagtcaaaa acgtgaacat
    81661 cgtgaacgta cgtgcgaaat tcaaacgtat gggcaaatat gcaggatata caaaaaaacg
    81721 tcgcaaagcg atcgttacat tgactgaaga ttcaaaagaa atccaattat tcgaagctgc
    81781 tgaataagca ctaatagata actcattaaa ttaggaggga aaaacgtggc gattaaaaag
    81841 tacaaaccta cctcaaatgg tcgtcgtaac atgacaggtt ctgattttgc tgaaatcaca
    81901 acatcaacac ctgaaaaatc attgttacaa ccattgaaaa accatgctgg acgtaacaac
    81961 aacggccgca tcactgtacg tcatcaaggt ggcggacaca aacgccaata tcgcgtgatc
    82021 gacttcaaac gtaacaaaga taacgttgtt gcaactgttc aaacgatcga atatgatcca
    82081 aaccgttcag ctaacatcgc gttagtacac tatgaagatg gagtgaaagc ttacatctta
    82141 gcacctaaag gactagaagt gggtatgaaa cttgtttcag gtccagaagc agatatcaaa
    82201 gtcggaaatg ctcttccatt agaaaacatt ccagttggta ctgttatcca caacattgaa
    82261 atgaaacctg gtaaaggtgg acaattgatc cgttctgctg gtacaagtgc tcaagtactt
    82321 ggtaaagaag gcaaatacgt attgatccgc ttgaactctg gtgaagttcg tatgatctta
    82381 gctgcatgcc gtgctacaat cggttctgta ggtaacgaac aacacgaatt aatcaacatc
    82441 ggtaaagctg gacgctctcg ttggatgcgt aaacgcccaa ctgtacgtgg tagcgtaatg
    82501 aaccctaatg atcacccaca cggtggtggt gaaggtaaag ctcctatcgg acgtaaagca
    82561 ccagtttctc cttggggtca accagctctt ggttacaaaa ctcgtaacaa aaaagctaaa
    82621 tcagacaaac ttattgttcg tcgtcgcaaa aataaataat tactttgacc atgtgtcgca
    82681 cattttgaga ggaggttcac catgggtcgt agtttaaaga aaggaccttt tgtcgatgag
    82741 catttaatga aaaaagttga agctcaagca ggggttgaaa agaaaaaagt tatcaaaact
    82801 tggtcacgcc gttcaacagt tttcccaagt tttgttggat ataccatcgc agtttatgat
    82861 ggacgtaaac atgtaccagt ttacatccaa gaagacatgg taggacacaa attaggtgaa
    82921 tttgcaccta caagaactta tcgtggacat gctgctgacg ataagaaaac gaaacgctaa
    82981 tttgagggga ggataaatcc aaatggcaga acaaatcaca tcagctaaag caactgcaaa
    83041 aacagttcgc acttcacctc gaaaagcccg tttagtaatt gaccttatca gaggtaaaag
    83101 tgtcgcagat gcaatttcaa tcttgaaatt cacaccaaac aaatctgctg gaatcattga
    83161 aaaagtattg atgtcagcag ttgcgaatgc agaaaataac tttgacttag atgttgaaaa
    83221 cttggtagta agcgaagctt ttgttaacga aggacctaca atgaaacgtt tccgtcctcg
    83281 tgcaaaagga tcagcttctc caatcaacaa acgtacaagt catatcacgg tagtcgtatc
    83341 agaaaaataa ggagggataa tcagtgggtc aaaaagtaca tccaattgga atgcgtgtag
    83401 gcatcatccg cgactgggat gctaaatggt atgctgaaaa agagtatgct gagttcttac
    83461 acgaagattt aagaatccgt aaatttattt caactaaact tgctgatgct gctgtatcaa
    83521 cagttgaaat cgaacgcgca acaggtcgcg taaacatttc aattcacaca gctaaaccag
    83581 gtatggttat tggtaaaggc ggttctgaag tcgaaagcct aagaaaagaa ttaaacaaat
    83641 taactggtaa aagaatccat atcaatatcg tggaaatcaa aaaaccagat ctagatgcaa
    83701 aattagtagg tgaaggaatc gcacgtcaat tagaaaaccg tgttgctttc cgtcgcgctc
    83761 aaaaacaagc catccaacgc tcaatgcgtg ctggcgctca agggatcaaa actcaagtat
    83821 ctggtcgtct aaacggagca gatatcgctc gttcagaagg atactcagaa ggaactgttc
    83881 ctcttcatac tttacgtgcg gacattgatt acgcatggga agaagcagat acaacatacg
    83941 gaaaactagg agttaaagtg tggatctatc gtggagaaat tcttccaact aaaaaaaaca
    84001 ctgagaaagg agggaaataa tcatgttagt acctaaacgt gtaaaacacc gtcgtgaatt
    84061 ccgcggaaaa atgcgcgggg aagctaaagg cggaaaagaa gtagcattcg gtgaatacgg
    84121 tttgcaagct gttgattcac attggatcac aaaccgccaa atcgaagctg ctcgtatcgc
    84181 aatgactcgt tacatgaaac gtggtgggaa agtatggatt aaaattttcc ctcacaaatc
    84241 ttatactgcc aaagcaattg gggtacgtat gggttctggt aaaggggcac ctgaaggatg
    84301 ggttgcacca gtaaaacgtg gtaaaatcat gtttgaaatc gcaggcgttc ctgaagaagt
    84361 agctcgtgaa gcgttacgtc tagcttctca caaattacca atgaaaacta agatcgtaaa
    84421 acgtgaggaa atgggtggtg aatcgaatga aggttaaaga aatcagagaa ttaaccactg
    84481 ccgaaatgct tgatcaagaa aaacaattaa aagaagaatt gtttaatctt agattccaat
    84541 tagcaacagg tcaattagaa aacactgcac gtattaaaga agtacgtaaa tcgattgcac
    84601 gcatcaaaac tgtgttgcgt gaacaagcta agtaattatg gaaggaggcc attaagcgta
    84661 tgactgaagg aagaaatcaa cgcaaagttt atcaaggtcg cgtggtttca gacaaaatgg
    84721 ataaaacaat taccgttgct gtcgaaacaa agaaaaacca ccctatctat ggcaaacgca
    84781 tgaactattc taagaaatac aaagtgcatg atgaaaacaa cacagcaaaa gttggcgaca
    84841 tcgtgagaat tatggaaact cgtccattat cagctacaaa acgtttccgt ttgttggaag
    84901 tagtcgaaga agcagttatt atctaataac acgagatttt cctatataga ttgaatgcaa
    84961 aatctgaaag gaggatacac aacgtgatcc aagcagaaag tcgtttaaaa gtcgctgata
    85021 actcaggcgc acgtgaaatt ttgacgatca aagtccttgg tggatctggt cgtaaaactg
    85081 ctaacatcgg tgatgtgatc gttgctacgg ttaaacaagc aacgccaggt ggggttgtca
    85141 aaaaaggtga cgtcgttaaa gccgttatcg ttcgaacaaa atcaggagct cgtcgtacag
    85201 acggttcata tattaaattt gatgaaaatg ctgcagtgat tattcgtgat gataaaagcc
    85261 ctcgtggaac acgtatcttt gggccagttg cacgtgaact acgtgaaaac aacttcatga
    85321 agatcgtttc actagcacca gaagttttat aatcttgaga cacttatcaa aggaggtgcg
    85381 aaacagttat gtttgttaaa aaaggcgata aagttaaagt tatcactgga aaagacaaaa
    85441 acaaagaagg cgttgtacta gcagcgttcc cgaaaaaaga taaagttatt gtcgaaggtg
    85501 taaatgtcgt taaaaaacac caaaaacctt ctcaagctgc tcctcaaggt ggaattgttg
    85561 agatggaagc gccaattcat gtttctaacg tgatggtggt tgactctact ggtgtagctg
    85621 gccgagttgg ctacaaagaa gtagacggca aaaaagtccg tgtttctaaa aaaaccggtg
    85681 aagttttaga taaataaaag tttaaggaag gagggtctta ctgaatgaac cgcctaaaag
    85741 aaaaatatct taaagaagta actccatcat tgatggaaaa atttaactat agctctgtta
    85801 tgcaaacacc taaagttgaa aaaatcgtca tcaacatggg tgttggtgat gcggtatcaa
    85861 acgctaaaaa cttagataaa gcagttgaag aattaacttt gatcactggt caaaaaccaa
    85921 tgattacaaa agctaaaaaa tcaatcgctg gattccgttt acgtgaagga atgccaattg
    85981 gtgcaaaagt tacattgcgc ggagaaagaa tgtacgaatt cttagacaaa ttggtttctg
    86041 tttcactacc acgtgtacgt gacttccatg gtgtaagtaa aaaagccttt gacggtcgtg
    86101 gaaactatac tttaggtatt aaagaacaat tgatcttccc agaagtagat tatgatttag
    86161 tagataaagt acgtggtatg gacatcgtta ttgtaacaac agcaaactct gatgaagaat
    86221 ctcgtgagtt gttgacacaa ttaggcatgc cattccaaaa ataattaaag gaggcgaact
    86281 acgtggctaa aaaatcaatg attgctaaaa acaaacgtcc tgcaaaattt tcaacacaag
    86341 cttatactcg ttgcgaacgt tgcggacgtc cacattcagt ttatcgtaag ttccatcttt
    86401 gccgtatttg cttccgcgaa cttgcctata aaggtcaaat tcccggcgtg aagaaagcta
    86461 gctggtaaaa agtaaattcg cataagaagg aggtaaaaga tcaatggtca tgacagatcc
    86521 aattgcagat tttctaactc gtatccgtaa cgcaaacatg gttaaacatg agtctttaga
    86581 agtacctgca tcaaaaatta aacgtgacat cgctgaaatc ttgaaacgtg aaggtttcgt
    86641 tcgtgatgtt gaatacatcg aagatgacaa acaaggcgtg atccgtgttt tcctaaaatt
    86701 tggtaaaaac ggcgaacgtg ttatcacaaa cttaaaacgt atctctaaac caggtttgcg
    86761 tgcttatgtc aaagctgacg aagtaccaaa agtattgaac ggtttaggta tcgcaatcat
    86821 ttcgacttct gaaggtgttg tcactgataa agaagctcgt gaaaaaaata tcggcggcga
    86881 agttatcgct tacgtatggt aatcaagtag aatctacaag gaggtgtctt taagtgagcc
    86941 gtatcggaaa taaagtcgtt gttatccctg aaggagtaac agttactcaa gacggaaaca
    87001 acgttacagt taaaggacca aaaggtgaat tgactcgtac tttttcagca gatatcaaaa
    87061 tgaatatcga aggaaacgaa gtaactttca ctcgtccaaa cgacagtaaa gaaatgaaaa
    87121 caattcatgg aacaactcgt gcgaacttca acaacatggt tgtaggtgtc agcgaaggtt
    87181 tccaaaaagc gttagaacta atcggggttg ggtaccgtgc acaattacaa ggatcaaaac
    87241 ttgtattgaa cgttggttac tcacatccag tagaaatcac accaccagct ggagtaactg
    87301 ttgaagtacc agctaacaca caagtaattg ttaaaggtgc gaacaaagaa gaagttggcg
    87361 aattagctgc aaacattcgt ggaactcgtc ctccagaacc ttataaaggt aaaggtattc
    87421 gttatgttgg cgaatatgta cgccgtaaag aaggtaaaac tggtaaataa tcgtttagaa
    87481 aaattgcata gaagccagca gcaggaaaaa ggcatttggc tgaagtttac cttcaaaaaa
    87541 atacattttt acttgtgccg cagcttctat ttttcgaaac gtatttactg cttgaaatag
    87601 tagtacaata aaaataaaga ggtgacaatt gtgattacaa aaccagataa gaacaaaaca
    87661 cgtcaaaaga gacatcgtcg tgtacgtaac aatatctctg gtactgctga gcgcccacgc
    87721 ttgaacgttt ttcgttctaa caaaaacatc tacgctcaaa ttattgatga cgtagcgggt
    87781 gtaacgctag caagtgcctc taccttggat aaagaaattt caggtggaac aaaaacagaa
    87841 gcagcacaag ctgtcggtaa actagttgct gaacgtgcag ctgaaaaagg cattaaagta
    87901 gtagtctttg accgtggtgg atacctttac catggccgtg tgcaagcttt agctgaagct
    87961 gctcgcgaaa atggactaga attttagaag aaggaggaat accattcatg gtttatatcg
    88021 atccaaaaca tttggaatta gaagaccgcg ttgttgcaat taaccgtgta acaaaagttg
    88081 ttaaaggtgg acgtcgtcta cgttttgctg ctttagttgt tgtcggtgac aaaaacggac
    88141 acgtagggtt tggtacaggt aaagctcaag aagttcctga agcaatccgt aaagcaattg
    88201 aagatgcgaa gaaaaactta gttgaagtac ctatggttgg ttcaacaatc ccacacgaag
    88261 taatcggtgc ttttagtggt ggtagaatcc taatgaaacc tgctgtagaa ggttctgggg
    88321 ttgctgctgg tggaccagtt cgtgccgtat tagaattagc tggggtagca gatatcactt
    88381 ctaaatcttt aggctcaaat acaccaatca acgttgttcg cgcaacagtt gaaggtttga
    88441 aacaattgaa acgtgcagaa gaagttgcag aacttcgcgg caaatcagtt gaagaattaa
    88501 tcggataagg aggacaacaa taatggctga attaaaagtt actttaaaac gcagtattat
    88561 cggacgtcct caaaaccaac gcgatacagt taaagcgtta ggtcttacaa agattaacag
    88621 ttcagtggtt aagccttcta atgaagcaat taaaggcatg atcaatactg tttctcacct
    88681 agtggacgtt gaagaaattt aatttagaaa aatcataact agaacattaa ggaggtgcca
    88741 aacctatgaa acttcatgaa ttaaaacctg ctgaaggttc acgccaagta cgtaaccgtg
    88801 ttggtcgtgg tacttcatct ggtaacggaa aaactgccgg acgcggacaa aaaggacaaa
    88861 aagctcgttc aggcggcggt gtgcgtttag gatttgaagg gggacaaaca ccattgttcc
    88921 gtcgtttacc aaaacgagga ttcacaaacg tgaaccgtaa agactatgca gtcattaatc
    88981 ttgatgtatt gaaccgcttt gaagacggag ctgaagtaac tcctgttgct ttagttgaag
    89041 ctggaatcgt gaaaaacgaa aaagctggaa tcaaagtatt agctaatggg gaactaaaca
    89101 agaaattaac tgtgaaagca gcaaaattct ctaaagcagc tcaagaagca attgaagcgg
    89161 ctggtggatc aatcgaggtg atctaatgtt tagactatta aaagatgctt ttaaagtaaa
    89221 agacattaga tcgaaaatcc tatttactgt atttgtgttg tttgtatttc gcctaggtgc
    89281 acatattact gtaccaggcg taaatgctgc ttcattgcaa aacctttctt ctttgccatt
    89341 tttcaacatg ttgaacttgg taagtggtag tgcgatgcaa aacttttcca ttttctcaat
    89401 gggggtttca ccatacatta ctgcttctat cgtcattcag cttcttcaaa tggacatcgt
    89461 gcctcgattt gttgaatggt cgaaacaagg ggaagttggt cgtaaaaaac tgaatcaagc
    89521 gactcgatat ctgacattag tattggcatt tatccaatct gtcggtatca ctgctggatt
    89581 caatcaatac gctcaattag gtttcgtgaa taatcctaac gtagcaactt acgtaacgat
    89641 cggtttgatt ctaacagccg gtacgatgtt tgttacttgg ctaggagaac agatcacaga
    89701 aaaaggtatc ggaaatggcg tatcaatgat catttttgca ggtatcattt ctagattgcc
    89761 tgaaagtatc agagaaattt atgaagatta ctttataaat attgatcctt cagacatatg
    89821 gaaatctgct atttttgtgg ccattttact agtagcggtc ttgttgatcg tgacattcgt
    89881 aacatttttc caacaagctg aacgcaagat cccgatccaa tatacgaaac gcgtagctgg
    89941 cgcgcctaca agcagctatc tgccgttgaa agtaaatgca gctggagtta ttccagttat
    90001 ctttgctagt tcgtttattg ctacgccaaa tgctgtttta caagcattga gcggtagatt
    90061 cggttctgaa aactggtaca aagtgatgat ggagatcttt aactataata cagcacctgg
    90121 tgctacgatt tatacgattc tgatcgttgc cttcactttc ttctacgcct ttgttcaagt
    90181 aaaccctgag aaattagcgg aaaacttgca aaagcaagga agttatatac caagcgtacg
    90241 ccctggtaag gggactgaag agtatgtctc aagattactg atgcgtttaa gtacagttgg
    90301 tgcagtcttc cttggtttag tggcattgct tccaatcatt gctcaaatgg tttgggatct
    90361 tccacaatca atcggattag gcggtacaag cttactgatc gttatcggtg tagctttaga
    90421 aactgcgaaa cagttagaag gcttaatgct gaaacgtaaa tatgttggat tcattgagta
    90481 agaaagcgtg ttgaggtttc ccctcaacac acgttctcac acatttatta ggagggaaaa
    90541 caatgaacct cattttaatg gggctgccag gcgcaggtaa aggaacacaa gctgaaaaaa
    90601 tcattgatgc ttatggtatt ccgcacatct caacaggaga tatgttccgc gcagcgatgc
    90661 aaaacgaaac agctcttggc ctggaagcaa agtcttatat ggataaaggt gcattagttc
    90721 ctgatgaagt aacaaatgga atcgtgaaag agcgactagc tgaaccagat acagagaaag
    90781 gcttcttatt agatggcttt ccacgtacgc tagatcaagc aaaagctctg gacgcaatgc
    90841 taaaagattt gaataaaaaa attgatgctg tcatcgatat ccatgttggt gaagaaatct
    90901 tggtcgaacg tctagccggc cgatttatct gcagcaattg tggagcaact taccataaaa
    90961 ttttcaaccc tacaaaagtt gaagacacat gtgatcgttg cggtgggcat gaattctatc
    91021 aaagagaaga tgataaacct gagacggtta aaaatcgtct ggctatcaac atcaaaaata
    91081 gtgaaccaat cttggcttat tataaagaac aaggtttgct aaacactatt gatggtgctc
    91141 gtgaaatcga tgctgtattt gcagatgtac aaaaaatcat tgaaaaatag cacgattgcc
    91201 cgtagccgac ttgcattatg cagttactct tgtcaagttc aataaattat gatagaatat
    91261 gtcagtccga cttctagaga atcctctaga tgatccattt tgagaatttt gaggtgggaa
    91321 ctgcagtttc cgccatttta tcgtgtgaaa atgcgaaaca agtacaagga ggtactgtgc
    91381 gtggcaaaag aagatatgat tgaagtcgaa ggtacagtcg tcgaaacttt gccgaatgca
    91441 atgtttaaag ttgaactaga aaacggacac caagttcttg ctactgtttc aggtaaaatt
    91501 cgtatgcatt acatccgtat cttacctggt gacaaagtaa cggttgaatt gtctccatac
    91561 gatcttaacc gtggccgtat tacttatcgc tttaaataat tgtactccgt aaaactacag
    91621 gaggtattat catgaaagta agaccatcag taaaaccaat gtgcgaacat tgtaaagtaa
    91681 ttcgtcgtaa aggacgcgtt atggtgattt gcccagcaaa tccaaaacat aaacaacgtc
    91741 aaggataatt ggaggtgcta taaatatggc tcgtattgca ggagtagata ttcctcgtga
    91801 taaacgtgta gtagtttcac ttacttatat ctatggtatt ggtaacacta ctgctaaaaa
    91861 gatcttagct gatgctggtg tatctgaaga tgttcgcgtt cgtgaattaa cgaatgaaca
    91921 aacagatgct atccgtgcag aagtagataa attaaaagtt gaaggggatc ttcgtcgtga
    91981 agtgaacttg aacatcaaac gtttgatgga aatcggttct taccgtggaa tccgtcatcg
    92041 ccgtggattg cctgttcgtg gacaaaacac gaaaaacaat gcacgtactc gtaaaggccc
    92101 agctcgcgct atcgctggca agaaaaaata attcttaagt gaaggaggtt aaaacttcat
    92161 ggcagcaaaa aaagtgaatc gtaaacgccg tgtgaagaag aatatagaag caggtattgc
    92221 acatatccat tctacattca ataacactat catcatgatc actgatactc acggaaatgc
    92281 attagcgtgg tcatcagctg gttcattagg tttcaaagga agcaaaaaat caactccttt
    92341 tgccgctcaa atggcagcag aaactgctac aaaagcagca atggaacacg gattaaagac
    92401 tgttgaagta acagttaaag gacctggttc tggacgtgaa gcagcaattc gttcattaca
    92461 agctacaggt ttagaagtga ctgcaattcg tgacgtgact ccagttcctc ataatggtgc
    92521 ccgccctcca aaacgccgtc gtgtttaatg agtgccgctc attttgagtt ttatcagtaa
    92581 cgtcattgaa caagacactt ttcgttttga aaggggtaaa gataagaatg attgagttcg
    92641 aaaaaccaag aatcgcaaaa attgatgaag aaaaagatta tggcaagttc atcgttgaac
    92701 ctcttgaaag agggtatggg actactttag ggaattccct acgtcgtatt ttattatctt
    92761 ctttgccagg tgctgccatc actaatattc aaatcgatgg tgtactgcat gaattctcta
    92821 ccatcaaagg tgttagagaa gacgtcactc aaatcatctt gaacattaaa ggcttagcgc
    92881 tgaaaatgta tggccaagaa gaaaaaaccc ttgaaatcga tattaccgga cctgctacag
    92941 taactgctgg cgatattatc gttgatagtg atgtagaaat tcttaacaaa gatatgtaca
    93001 tctgtagtgt ctctgaagga gctacgttcc atgctcgctt aacagtgaaa cctggacgtg
    93061 gttatgttca agcagatgaa aataaaaaag aagatatgcc aattggcgtt cttccagtcg
    93121 attcaatcta cacacctgtt cgtcgtgtga actatcaagt tgagaacaca cgtgttggac
    93181 accgtgaaga ttttgataaa ttgacgatgg agatttggac agatggttca attgaaccgt
    93241 tggaagcaat gagtttgtct gcgaaaatca tgactgaaca tttggatatt tttgtgaact
    93301 taactgatga agcaaaaaat gctgaaatca tggtcgaaaa agaagaaaca caaaaagaaa
    93361 aaatgttgga aatgacgatc gaagagttag acttgtctgt tcgctcttac aattgtttga
    93421 aacgtgcagg aatcaatact gtacaagaac ttacaaataa atctgagcct gaaatgatca
    93481 aagtccgtaa cttaggacgt aaatcattag aagaagttaa agcaaaattg cacgacttag
    93541 gtttaggttt acgtaaagaa gattaaaacc ttttacgaag gagggaaacc aacgtgagtt
    93601 atcgtaaact aggacgcaca tctagccaac gtaaagcgat gttgcgtgat ttaacaactg
    93661 atttattaat caacgaacgt attgtgacta ctgaagctcg tgcgaaagaa gttcgctcaa
    93721 ctgcagaaaa aatgatcact ttaggtaaac gcggagattt gcatgcacgt cgtcaagctg
    93781 cggctttcgt acgtaatgaa gttgccagcg tgcgtgaaga aaatgaggac atcgtcattg
    93841 aatcagcttt acaaaaactg ttcaacgata ttgcacctcg ttacgcagaa cgtcaaggcg
    93901 gatacacacg cattttgaag acagaaccaa gacgcggtga tggtgcacca atggttgtct
    93961 tagaacttgt ctaaaatcac actaataaca tcactttata gatgattctt ttagagtgtt
    94021 atgatgttgg aagatatttt tccgagtcta gctcagcgct gctcctcaag cgaatatcgc
    94081 ttggggagta agcactcatc ataaagtgtt tttttatacc ttcaattacc tgtcatgaca
    94141 gatatgtttg aaggcataaa aaaacatttt aagcgagaaa taattgaaaa ttttgtcttt
    94201 ttttgatagt gttagtagga actttaggat gaagaaggag taatcatgga gccaattatt
    94261 gaattagaaa agataaatta taaataccag ccagatgatc ttcgccccgc attgaaagat
    94321 gtctccttta caattgataa aggtgagtgg atcgctatta ttggacacaa tggttcagga
    94381 aaatcgacac ttgccaaaac gatcaatgga ttgcttctgc cagaatcagg gatcgtgaaa
    94441 gtgggaaatc aaatattgga tgaagaaaat atttggacga tccgacagat ggttggaatg
    94501 gtttttcaaa atccagacaa tcagtttgtt ggttcgacag tagaagatga cgttgctttt
    94561 ggtcttgaaa atcaagggat tcccagagaa gaaatgctag tgcgtgtgaa agatgcactt
    94621 gagaaagtta gaatggctga gtttgcttca cgcgagcctg ctcgtttatc aggagggcaa
    94681 aaacaacgtg ttgccattgc cggcgtggtt gccttacgac ctgatatcat tattttagat
    94741 gaagcaacca gtatgctaga tccagaaggt cgtgaagaag tgatctctac gatcaagaag
    94801 atcaaagaag aaagtcaatt gaccgttata tctatcactc atgatattga tgaagcagct
    94861 aatgccaatc ggatactagt gatgagacaa ggcgaacttg tccgtgaagg tacaccaaaa
    94921 gaaatttttt ctgctggtcc tgaactgatc gacttaggtc tagatctacc atttcctgaa
    94981 aaactgaaga gcgcactgaa agaacgtggg gttgatgtgc ccagtgaata tatgacagaa
    95041 gaaaggatgg tggattggtt atggacatcc gttttgaaca agtagacttc acttatcagc
    95101 cgaatacacc atttgaacaa agagccttat ttgacatcaa tatgacgatc aaagaaaaca
    95161 gttatactgc attagtaggg cataccggaa gcgggaaatc aaccttactt cagcatttga
    95221 atgcgcttgt taagccaaca agcggtacag tccatattgg agaacgagat attcagccgg
    95281 atacggataa taagaattta aagcccatcc gaaaaaaagt tggcatcgtc tttcagtttc
    95341 cagaagcaca gctattcgaa gaaacggtag caaaagacat tgctttcggt cctaaaaact
    95401 ttggtgtcag cgaagaagaa gcactagtcc tagcaaaaga aacattagaa caagttgggc
    95461 tggatgaaag ctatttggaa cgttcgccat ttgaactttc aggagggcaa atgcgtagag
    95521 tagcaatcgc tggtgtgctt gccatgaggc cggaagtact tgtattggat gaaccaacgg
    95581 caggacttga tccccagggt agaaaagaaa tgatggagat gttttggcgt cttcataagg
    95641 aacagcagat cactattgta ttagttacgc atttaatgga tgatgtagcc aattttgcag
    95701 attatgtcta tgtgttggaa aagggacgaa tcgttaatag cggggagccg caagaggtct
    95761 ttcaaaacat tgaatggcta aaagaaaaac aactaggcgt acctactgcc accgagtttg
    95821 cagaagaatt aatggctaaa gggatgaact ttgctacctt gcctttgaca gctgaagaat
    95881 tagcagacgc tatcgtccat tatgctggag gaaatgccca tgatgaataa attgatattt
    95941 ggtcgttata tgcctggaga ttccttgatc catcgattgg atccccgagc taaattatta
    96001 gccagttttt attttatcgg aatcattttt ttagcaaata attgggaaac gtaccttttg
    96061 ttggcatttt tcacattact ttctgtcttc ttgtcaaaag tagatttgaa attttttatc
    96121 cgaggcattc gcccattgat ctggctaatc ctcttcactg tagctttgca ggtcttgttt
    96181 acaagtggcg gagaaactta ttggagttgg ggtgttttcc atatcactga atttggtgtg
    96241 atgaacggcc tctttatttt ctgtcgattc gtgttgatca tttttatgtc gactctactc
    96301 acgcttacta caccgccttt ggaattatcg gatgcgattg agtacttgct tcgtccattg
    96361 aaagccgtac ggttcccagt ccacgaaatt tcattgatgc tgtcgattgc tcttcgtttt
    96421 gtgcctacat tgatggacga aacagaaaag atcatgaacg ctcagcgcgc tcgcggtgtt
    96481 gattttggtg aaggaaacct agttcagaaa atgaaagcag tcattccttt gctgattcct
    96541 ttatttgtca gcagcttcaa ccgtgcggaa gatcttgcga ctgctatgga agcaagaggc
    96601 tacaaaggtg gggaaggaag aacgaaatat tgtgtattgc attggcataa tagagacacg
    96661 atggttatca ttgcttttgt attattaact gtgctactga tctttttgag aggataaacg
    96721 ttcagtgggc cgctatctat tcttttcttg ctgatctgtt tgcaagaaag gatgcgagca
    96781 gtgtatgaca agaaatatta gggtctgtgg cagactaagg tcacaggcct ctttctttta
    96841 tctgaaaaga aagaacgaaa aaattttata aaaaaatcat tattccagat aaccttttag
    96901 gaacaaagga gagaaaaaca tggtacgtta caaagcaatc attgcatacg acggaacaaa
    96961 ttttaatgga ttccaaaaac agccaaatgg gcgtactgtt caagaagaag tagaaaaaac
    97021 attacaaaaa atggcaaatg gaaaagaaat cacggtcttt ggttcgggaa ggacagatgc
    97081 cggagtacat gcgattgggc aagtaatcca ttttgattat ccagaggagc gtccgttaga
    97141 acgaatgcgt ttcgcgctag atacccagtc accagaggat attgctgtaa gacaagtaga
    97201 aattgtttca gaagacttcc acgcaagata tttggtcaaa gaaaagacgt atcaatttcg
    97261 agtggatata gggaaaccac gcagtccttt tcgacgccat tatgcaagtt attttcctta
    97321 ccctcttgat ttggaaaaaa ttcagcgggc gcttcctgat ttattaggga ctcacgattt
    97381 cacctctttt tgtgcatcag gaagctcgat agaggataaa gtacgtacga tctacgaggc
    97441 taagatggag gtaaatgaaa caaaagacga attgttgttt acatttaggg gaaatggctt
    97501 cttgtataag atgatacgga tcttagtagg aacgcttttg aaaattggca atggccgatt
    97561 gcctgaagat agtatcccag atattattgc gaaaaaagat cgtaatgcag caggacctac
    97621 agcacatcct gaaggacttt atttgtatga agtgaaatat gaataagagg ttgtgacaga
    97681 agtggtcagc ttcaagaaat aagaaggaat ttacgaaaat tacttctcaa aattttgcaa
    97741 aatttcggct tattttcgaa ggagctactt ctggaacacc gtgaatcaga ggttgtgaaa
    97801 aagctgccct gcatcaagta ataagaacaa ccaaacaaaa atagctcgtc atatttttcg
    97861 tttggttggg cttattaccg cagatgcaag cttttgaaca ccgtttaagg aagaggttgt
    97921 gaaatcagcg ttttgacctg agtattagag aaacaaacgg aaaaatagtt cctcatattt
    97981 tgccgtttgt tgagctaata ccgaaggtca gctgattgaa caccgtttaa gaaagaggtc
    98041 gtgagcctgt catttaactc tgagtcacaa gtaacaattt caaaaaacag cttctcatct
    98101 ttgatgaata tcgtgacttg tggacgaggc gttgataagt gaatcatctt tttgttacct
    98161 attttttctg taaccaaaaa acgatggaac gttgttttga ttgcccttaa tgaggacagt
    98221 cggaacaggt ttgtcatttt tatatttaaa tggcacaaat ttttctaatt atttgtcatt
    98281 tagcgctgaa aatttttgct atttatctaa aaaagtgata actacttaag atgaagcaga
    98341 atatttacgc catacggcat acaaccgcga aaaatataaa aaaaagaaaa cgattgaacg
    98401 cgtttttgca gtcgcaaagg aaaagcatgg aatgcgctac atcaagtatc gagacttgga
    98461 aaacaatcag gtgtatacgc tgattgtttt tgctgcaatg aatctgaaaa agttgtccac
    98521 ttggcagttg gaacatatgt cttcatatct tttattatac aaaaatagca aaagcaccag
    98581 tctacactct tagtaaagag gaaactgatc cttttgtcta cattcttaaa gtacttaaac
    98641 taagtacttt attttactct ttaggattga tacagtagca tctatccctt tattaataat
    98701 cttttatttt tttaaataaa gatgttgtct ccatcttcag gcactaaaac tttttcggaa
    98761 attccttttt ctttattgaa agactttaat tcttctcttg acagtcccca atggtttaca
    98821 gcttccatat gaacggcaat aattgtggaa tctggtattg ctttatgcaa ttcatataaa
    98881 tcgtctttcc ccataataag agattctcca actaaaaaat gattatctcc agcatttgct
    98941 actatgattt ctggattata ctgatcaata gtttgtttaa cagcttcata ccaaactgta
    99001 tctcctgtaa agtatagtgt cttctcagtc gaatgtttga aaacaatacc gcaaacatta
    99061 cctacataat tcaagatttc tcctctgcca tgtttgcctt ttgttttaac caattgtata
    99121 gattcaaaaa ctgtgtcttc tcgtagtacc tccacatttt taaaaccata tagtcgaatt
    99181 tcattcgcat cattttcatc ttgcacaaat aattttattt ctttaggtag gacctctttc
    99241 gctatatcgt cccaatgatc tagatgtaaa tgtgttacaa taacagcatc aataccgttg
    99301 ataatatctt cgactggcat tggcaaatca actagaggat tcatttgatc ttttcttggt
    99361 gatggaaaag gacctttcga aataaatggt ggaagtgttc ctttttccgc taacattgga
    99421 tcaattaaaa attttttacc tccatagtct aagatagctg ttgcattacg aatgtgatgt
    99481 atattcataa acgttgtctc ctttttgttg atatgaaata tttttagtat aattcaattc
    99541 catacaataa ataaaccgaa caaaaaaagt cttttactat ttttacttaa tttatgaaag
    99601 gttgtttacc atgttagacc aaacagatat aaatatcatt gaggaactat caaaaaatag
    99661 tcgaatcaca atgaaagaac ttggagaaaa agtacatttg actggacccg ctgtctcggc
    99721 gagagtgaca aaactagagg aaagtggagt tattgaaaat tatacagtaa aattaaatat
    99781 ggaaaagcta gggttttcga ttcacgcttt tttaattata attacgcaaa atttaaatca
    99841 taaaccctat ttatcattta ttaaaaatca tgaaaaattc ttgattagaa attataagat
    99901 tagtggaggg ggctgttatc ttttggaatg tagatttact tcaaaaaaat caatgaacag
    99961 ctttttggaa cagcttaatg aatatgcgaa ttataaatta tctattgtta tagattaata
   100021 ataaaactag cagatggtaa aaatactaat atgcgagaca cacattcaac cataactata
   100081 taacttatca atttaaaact aaactgatgg aaacaagtaa ggcaaaaaca tttatatttt
   100141 gccctactta tttttttaat taaattcatt gatgattcat atttagaaaa ttctatgaag
   100201 gccaaatgag tatcctgtca cttttttaga taaatagcaa aaattttcag cgttaaatga
   100261 caaataatta gaaatatttg tgccatttaa atataaaaat gacaccaagt atatcatgaa
   100321 cgcacaaaaa gaccaacagg gtataccctg ttggtctaaa taaa
//
LOCUS       DAIGSZ010000002        89991 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.002, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000002 DAIGSZ010000000
VERSION     DAIGSZ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 89991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.002"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(69..1490)
                     /locus_tag="NOB31_000109"
     CDS             complement(69..1490)
                     /locus_tag="NOB31_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0972359.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1733..3610)
                     /gene="tdc"
                     /locus_tag="NOB31_000110"
     CDS             complement(1733..3610)
                     /gene="tdc"
                     /locus_tag="NOB31_000110"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCI0972360.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3901..5157)
                     /locus_tag="NOB31_000111"
     CDS             complement(3901..5157)
                     /locus_tag="NOB31_000111"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HCI0972361.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(5269..5474)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5737..7038
                     /locus_tag="NOB31_000112"
     CDS             5737..7038
                     /locus_tag="NOB31_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCI0972362.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7107..7706)
                     /locus_tag="NOB31_000113"
     CDS             complement(7107..7706)
                     /locus_tag="NOB31_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0972363.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            7961..8842
                     /locus_tag="NOB31_000114"
     CDS             7961..8842
                     /locus_tag="NOB31_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0972364.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8855..10465
                     /locus_tag="NOB31_000115"
     CDS             8855..10465
                     /locus_tag="NOB31_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCI0972365.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10542..11201)
                     /locus_tag="NOB31_000116"
     CDS             complement(10542..11201)
                     /locus_tag="NOB31_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI0972366.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(11484..12149)
                     /locus_tag="NOB31_000117"
     CDS             complement(11484..12149)
                     /locus_tag="NOB31_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HCI0972367.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(12296..12901)
                     /gene="dhaL"
                     /locus_tag="NOB31_000118"
     CDS             complement(12296..12901)
                     /gene="dhaL"
                     /locus_tag="NOB31_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HCI0972368.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(12929..13939)
                     /gene="dhaK"
                     /locus_tag="NOB31_000119"
     CDS             complement(12929..13939)
                     /gene="dhaK"
                     /locus_tag="NOB31_000119"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HCI0972369.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(13914..14360)
                     /gene="dhaM"
                     /locus_tag="NOB31_000120"
     CDS             complement(13914..14360)
                     /gene="dhaM"
                     /locus_tag="NOB31_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HCI0972370.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            14463..14783
                     /locus_tag="NOB31_000121"
     CDS             14463..14783
                     /locus_tag="NOB31_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HCI0972371.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(14895..15764)
                     /locus_tag="NOB31_000122"
     CDS             complement(14895..15764)
                     /locus_tag="NOB31_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI0972372.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(15860..17164)
                     /locus_tag="NOB31_000123"
     CDS             complement(15860..17164)
                     /locus_tag="NOB31_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0972373.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(17161..17670)
                     /locus_tag="NOB31_000124"
     CDS             complement(17161..17670)
                     /locus_tag="NOB31_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972374.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(17845..19980)
                     /locus_tag="NOB31_000125"
     CDS             complement(17845..19980)
                     /locus_tag="NOB31_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0972375.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(20063..21718)
                     /locus_tag="NOB31_000126"
     CDS             complement(20063..21718)
                     /locus_tag="NOB31_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0972376.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(21720..22034)
                     /locus_tag="NOB31_000127"
     CDS             complement(21720..22034)
                     /locus_tag="NOB31_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI0972377.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            22204..22464
                     /locus_tag="NOB31_000128"
     CDS             22204..22464
                     /locus_tag="NOB31_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HCI0972378.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            22478..22792
                     /locus_tag="NOB31_000129"
     CDS             22478..22792
                     /locus_tag="NOB31_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HCI0972379.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(23522..24076)
                     /locus_tag="NOB31_000130"
     CDS             complement(23522..24076)
                     /locus_tag="NOB31_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HCI0972380.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(24202..26131)
                     /locus_tag="NOB31_000131"
                     /pseudo
     CDS             complement(24202..26131)
                     /locus_tag="NOB31_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(26437..27153)
                     /locus_tag="NOB31_000132"
     CDS             complement(26437..27153)
                     /locus_tag="NOB31_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCI0972381.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(27154..28977)
                     /gene="glpO"
                     /locus_tag="NOB31_000133"
     CDS             complement(27154..28977)
                     /gene="glpO"
                     /locus_tag="NOB31_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HCI0972382.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(28991..30487)
                     /gene="glpK"
                     /locus_tag="NOB31_000134"
     CDS             complement(28991..30487)
                     /gene="glpK"
                     /locus_tag="NOB31_000134"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HCI0972383.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(30623..32083)
                     /locus_tag="NOB31_000135"
     CDS             complement(30623..32083)
                     /locus_tag="NOB31_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0972384.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(32073..33368)
                     /locus_tag="NOB31_000136"
     CDS             complement(32073..33368)
                     /locus_tag="NOB31_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0972385.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(33700..34377)
                     /locus_tag="NOB31_000137"
     CDS             complement(33700..34377)
                     /locus_tag="NOB31_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HCI0972386.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(34407..35498)
                     /locus_tag="NOB31_000138"
     CDS             complement(34407..35498)
                     /locus_tag="NOB31_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HCI0972387.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(35599..36033)
                     /locus_tag="NOB31_000139"
     CDS             complement(35599..36033)
                     /locus_tag="NOB31_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0972388.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(36617..38074)
                     /gene="ascB"
                     /locus_tag="NOB31_000140"
     CDS             complement(36617..38074)
                     /gene="ascB"
                     /locus_tag="NOB31_000140"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI0972389.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(38071..39966)
                     /locus_tag="NOB31_000141"
     CDS             complement(38071..39966)
                     /locus_tag="NOB31_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0972390.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(40024..41799)
                     /locus_tag="NOB31_000142"
     CDS             complement(40024..41799)
                     /locus_tag="NOB31_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCI0972391.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(41849..43345)
                     /locus_tag="NOB31_000143"
     CDS             complement(41849..43345)
                     /locus_tag="NOB31_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0972392.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(43539..45161)
                     /locus_tag="NOB31_000144"
     CDS             complement(43539..45161)
                     /locus_tag="NOB31_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCI0972393.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(45489..46802)
                     /locus_tag="NOB31_000145"
     CDS             complement(45489..46802)
                     /locus_tag="NOB31_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCI0972394.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(47047..47271)
                     /locus_tag="NOB31_000146"
     CDS             complement(47047..47271)
                     /locus_tag="NOB31_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972395.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(47291..47713)
                     /locus_tag="NOB31_000147"
     CDS             complement(47291..47713)
                     /locus_tag="NOB31_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HCI0972396.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(47855..48565)
                     /locus_tag="NOB31_000148"
     CDS             complement(47855..48565)
                     /locus_tag="NOB31_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972397.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(48583..49080)
                     /locus_tag="NOB31_000149"
     CDS             complement(48583..49080)
                     /locus_tag="NOB31_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0972398.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(49117..49569)
                     /locus_tag="NOB31_000150"
     CDS             complement(49117..49569)
                     /locus_tag="NOB31_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0972399.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(49704..50309)
                     /locus_tag="NOB31_000151"
     CDS             complement(49704..50309)
                     /locus_tag="NOB31_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI0972400.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(50759..51379)
                     /locus_tag="NOB31_000152"
     CDS             complement(50759..51379)
                     /locus_tag="NOB31_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HCI0972401.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(51381..52250)
                     /locus_tag="NOB31_000153"
     CDS             complement(51381..52250)
                     /locus_tag="NOB31_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HCI0972402.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(52273..52680)
                     /locus_tag="NOB31_000154"
     CDS             complement(52273..52680)
                     /locus_tag="NOB31_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCI0972403.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(52699..53988)
                     /locus_tag="NOB31_000155"
     CDS             complement(52699..53988)
                     /locus_tag="NOB31_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0972404.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(54015..54317)
                     /locus_tag="NOB31_000156"
     CDS             complement(54015..54317)
                     /locus_tag="NOB31_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0972405.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(54342..56435)
                     /locus_tag="NOB31_000157"
     CDS             complement(54342..56435)
                     /locus_tag="NOB31_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI0972406.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(56924..57688)
                     /locus_tag="NOB31_000158"
     CDS             complement(56924..57688)
                     /locus_tag="NOB31_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HCI0972407.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(57799..58668)
                     /gene="mdcB"
                     /locus_tag="NOB31_000159"
     CDS             complement(57799..58668)
                     /gene="mdcB"
                     /locus_tag="NOB31_000159"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HCI0972408.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(58693..59769)
                     /locus_tag="NOB31_000160"
     CDS             complement(58693..59769)
                     /locus_tag="NOB31_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HCI0972409.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(59793..60386)
                     /locus_tag="NOB31_000161"
     CDS             complement(59793..60386)
                     /locus_tag="NOB31_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HCI0972410.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(60390..62066)
                     /gene="mdcD"
                     /locus_tag="NOB31_000162"
     CDS             complement(60390..62066)
                     /gene="mdcD"
                     /locus_tag="NOB31_000162"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HCI0972411.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(62056..62355)
                     /locus_tag="NOB31_000163"
     CDS             complement(62056..62355)
                     /locus_tag="NOB31_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HCI0972412.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(62457..64103)
                     /gene="mdcA"
                     /locus_tag="NOB31_000164"
     CDS             complement(62457..64103)
                     /gene="mdcA"
                     /locus_tag="NOB31_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HCI0972413.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(64110..65021)
                     /locus_tag="NOB31_000165"
     CDS             complement(64110..65021)
                     /locus_tag="NOB31_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCI0972414.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            65141..65998
                     /locus_tag="NOB31_000166"
     CDS             65141..65998
                     /locus_tag="NOB31_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0972415.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(66185..66547)
                     /locus_tag="NOB31_000167"
     CDS             complement(66185..66547)
                     /locus_tag="NOB31_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HCI0972416.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            66893..68332
                     /locus_tag="NOB31_000168"
     CDS             66893..68332
                     /locus_tag="NOB31_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0972417.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(68339..70891)
                     /locus_tag="NOB31_000169"
     CDS             complement(68339..70891)
                     /locus_tag="NOB31_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HCI0972418.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(71005..72336)
                     /locus_tag="NOB31_000170"
     CDS             complement(71005..72336)
                     /locus_tag="NOB31_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0972419.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(72302..73780)
                     /locus_tag="NOB31_000171"
     CDS             complement(72302..73780)
                     /locus_tag="NOB31_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0972420.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(74085..75920)
                     /gene="tdc"
                     /locus_tag="NOB31_000172"
     CDS             complement(74085..75920)
                     /gene="tdc"
                     /locus_tag="NOB31_000172"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCI0972421.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            76390..77817
                     /locus_tag="NOB31_000173"
     CDS             76390..77817
                     /locus_tag="NOB31_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0972422.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(77909..78274)
                     /locus_tag="NOB31_000174"
     CDS             complement(77909..78274)
                     /locus_tag="NOB31_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCI0972423.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(78271..78636)
                     /locus_tag="NOB31_000175"
     CDS             complement(78271..78636)
                     /locus_tag="NOB31_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCI0972424.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(78828..79076)
                     /locus_tag="NOB31_000176"
     CDS             complement(78828..79076)
                     /locus_tag="NOB31_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972425.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            79075..79203
                     /locus_tag="NOB31_000177"
     CDS             79075..79203
                     /locus_tag="NOB31_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HCI0972426.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            79260..80954
                     /locus_tag="NOB31_000178"
     CDS             79260..80954
                     /locus_tag="NOB31_000178"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HCI0972427.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            80958..81077
                     /locus_tag="NOB31_000179"
                     /pseudo
     CDS             80958..81077
                     /locus_tag="NOB31_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            81728..82861
                     /locus_tag="NOB31_000180"
     CDS             81728..82861
                     /locus_tag="NOB31_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HCI0972428.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            82892..83212
                     /locus_tag="NOB31_000181"
     CDS             82892..83212
                     /locus_tag="NOB31_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HCI0972429.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(83241..83705)
                     /locus_tag="NOB31_000182"
     CDS             complement(83241..83705)
                     /locus_tag="NOB31_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0972430.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(83836..85089)
                     /locus_tag="NOB31_000183"
     CDS             complement(83836..85089)
                     /locus_tag="NOB31_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0972431.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(85118..85435)
                     /locus_tag="NOB31_000184"
     CDS             complement(85118..85435)
                     /locus_tag="NOB31_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0972432.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(85461..85781)
                     /locus_tag="NOB31_000185"
     CDS             complement(85461..85781)
                     /locus_tag="NOB31_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0972433.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(86245..87660)
                     /locus_tag="NOB31_000186"
     CDS             complement(86245..87660)
                     /locus_tag="NOB31_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0972434.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(87677..88993)
                     /locus_tag="NOB31_000187"
     CDS             complement(87677..88993)
                     /locus_tag="NOB31_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0972435.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(89143..89841)
                     /locus_tag="NOB31_000188"
     CDS             complement(89143..89841)
                     /locus_tag="NOB31_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HCI0972436.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT        26177 a        18965 c        15418 g        29431 t
ORIGIN      
        1 aaaactattc acttggcagg acctcctact aaatcagcga caaaacgtcg gctgaaagac
       61 ttattttttt atttttcttc taaacttttt tctacctcaa tcccccaaga atctttcttg
      121 aagtgattga tgatcaatgg aataacgaac atgaccactg tgatagctgc tactaataat
      181 gcatcactca atgtcgctgt acctaatgta gcaaatacga caacgatgat agagaagatc
      241 agcatgcagc tgactaccca agctaatccg tttccgtttt taccaattcg gtaaggacgt
      301 tcgaattctg gatgtttctt acgcatttta agcaatgaaa cagcaatcaa aatgtacacg
      361 atacaataaa taacagttgt agcatttgta agtgtcaaga atacagcact tacgtcatcc
      421 attacaccat aaagcaaagc aaataatgaa ataacgattg attgtgttag aacgacattt
      481 ctagatacgc cgtatttgtt ttctttatgg aatccgaatt ttggtggaag gaatccttca
      541 cgagctactt ggatgattgt ttttgatggt ccagtaaccc aagctgataa ttgtaaaagc
      601 acaccaataa ataccatgaa gctgaagata tttccgatca cttctggtaa gcctaggatt
      661 tgacagtcaa tcaagatagg ctgcgtgata tttgctaatt ccatttttcc atctggtacg
      721 acatttgcta caagcatcgc attgatgaca ttcaataaaa ctaatccgat caaagcgata
      781 aatacgcctt ttgtataatt ttttgttgcg tctttcaaac gaggcatgta aacagaactc
      841 atttcgatcc caacaaaaat aaatgtgata ccagctaagt atttcaatga atcaatatgt
      901 tccaagtcag ggaaagcttt tgaccatgaa aagtcaccta gatagccgtt tgagactagt
      961 ccgactttga aggctgccaa aacacctaaa acgaacatga tgactactgg gatatatacc
     1021 cctagccata caccgatgtt cccgccgact tttgccatat cgaatttcaa gttcaagatc
     1081 gtgatgatcc agtagataac taaaatacaa cctaaaacga accagtgatt attgccaagt
     1141 tctacattac caaatgtgtt tcctaacaat ggtcctaaag tagaagcgac cattaccata
     1201 cctgggaaca tttgcaccca taatagccat gcaacgacaa atccccattt gctgcccagt
     1261 gctgttttta cccataactg aggaccgcct tcttgaggaa gcatcgtgga aagctcaccg
     1321 gaaaccattg atatcggacc ggcaaaaaac aaaactgcaa aaattgaata aaaaatcaat
     1381 gtccaaccga ctgcggctaa cgtaggaata ctccgaaccg ttgcacacag tgccattgtc
     1441 agaccgataa aggtcccaag acccatttta cttacttcag atttactcac cgttgacact
     1501 ctccttgatt ttttggataa aataacggtg tctttgaagt agtttcagca ataaacgaaa
     1561 caattcagcg aatatttgag gggattcttt gagtttattg cttgaagggt ttcttcaaag
     1621 acaacctcaa aacaaaggga tcgaagagct taggtctccc cttgctcttc agatccaaac
     1681 atgcgtcaga aacagttagt attcaagctg ttttctaaca tgattacctt gcttattttg
     1741 cttcgcttgc caataattgg tctgcgtaga ttttttccaa tttttcttga agagctgctt
     1801 tgattttttc agcatattct tcaaagtgtt cttctttgtt catgtatggt gtcattacgc
     1861 tggcacgcaa tacagttact tttccggcac ggttccattc ttcatctgag aatcctagtt
     1921 ggttcacaaa ttgtaatggg ctgttgccat agtctgggat agcaaagtca gtatgtgaag
     1981 ttaagaactc attaccgtaa atgcttcctt tcacgtatga agaataatca tatacgtcat
     2041 ggttcaattt attcattgca actaagtcat cgttgccttt ttctttgaat acatagtcta
     2101 ccatattgaa atctggataa gttaatggat gaacttcgat ttctttgtct cctactttaa
     2161 atgacaagtc attcaagaag ttgtagaaac gatgtgcacc ttcgattgat gcacccatta
     2221 atttaccata tcctgtgaca ttcaaaggta agacatggtg tgctgcccaa acgctggctg
     2281 ctgttgcccc tgcttttgaa ccttccaaga tataagcccc aagtaatgct gggatatctg
     2341 cgcctttttc aaatacatat gtcgcaaagt aagagataac gtctctcatg cggatatctt
     2401 tgatgacgat accaccggca gaatatggaa catagcccat tttatgtggg tcaatcgtta
     2461 cagattctgc ttcttcgatt gctttatatg cactgtgtac ttcttctaag atataatctt
     2521 tgttttctgt aaagacattg tatttgtaat gaacatcttt taaatcttca aatggaatga
     2581 agttgttgtc ttcgtctaag aaaatcgcac ggccgtatcc gccataagca gcatctacgt
     2641 gtaagtagaa gtaaataccg tctttttcta atacgcgacg caatgcaacg attttatcga
     2701 taccgtcgat tgctccttct tctgttgatc ctacaacacc gactacacct aggattggtg
     2761 ttttttcagc tgctagacca cgaacgattt tttcaagttc gttgatgtcc atgcgatagt
     2821 tgtggtcaac tggcactgga atcacttggt ctaaaccgat accgatgatg tcggcagctt
     2881 ttagccatga atagtgttta gtttgtggaa ccaaccattt tcctaatttt tctaaatgtt
     2941 ttccgctacg tgctgagtga gctttgattt cgtcgatttt ttctgggacg ctgtctaaca
     3001 gattcatgat ttcttctgtt gacaagttca ttaattccca atcgcttttt ccagcaacta
     3061 gttcaggtgt cacttctttc attgcaagcg gcaatgattt gatgttgcgg gcataccaaa
     3121 gtccttctaa gtttgctaaa gaaccatcag caacgatgtg gccccagcca tctttatagc
     3181 tcattaattt tgcaaattcc attcctactt cttcttccat ttggcttgtt gcaggagaag
     3241 attcataggc aacgttatta ccattccata gcatagcaaa attgtacgct agtaaagatg
     3301 gcatcaatgt ttcagagttc atatgacccc agtaacgtcc ggcattatgc caaggaacgg
     3361 aatgggtacg catccgcgct gaaatttctg atagaacatc ctttgtttta ttcacagtgt
     3421 gttcaaaact agcactgctt ttttcttctg gcgtaataat aggcatgtct tgaggcatgt
     3481 agttttgacg ccagcctaaa tgttcatcca ccaattcatt caacaaagct ttatagattt
     3541 ggccgttctc agctttgtcc ccaatgaata gggcatttag gtttagatct ttcgacaatg
     3601 attcactcat agtgaaaccc tcctaaaaaa atatttaaat tttgtcgagc cctacattac
     3661 acctgttctt ctattctgta aactaagttt tggcctgatt tttaatcata ttttaatatg
     3721 tatcaattat ccgaattgtt cacacttttg aaataattaa aaaaaacgag ggaatttaca
     3781 aatgtaaact ccctcgcaaa gattgtatta acgacaacca gcgttctatt ttaggatggg
     3841 tttcaaaatt ggaatgttgt aatagtattt ccctttttca aggtaaaaac ttactaaatt
     3901 ctaatcaatt actttggcca aaaagtaatt tttcttacct tttcgaataa ccacaaactt
     3961 accatcgaat tcatcggatg gatttatgac aaaatttaaa tcggtaacgc ggtcaccgtt
     4021 aatacttata gctccgtttg aaacatcttc acgtgcttga cgtttagatg gttcaatttt
     4081 tgtggaaaca agcagttcca cgatattttc aggtgtgctt gaaatttcaa cgttcggcat
     4141 tttaccgaat ccttgcgcga tttcttccgc atttagttct ttaatatttc cagagaacaa
     4201 tgcttgcgtt attttttgcg cttctttcaa gtcttcttca ctatgcacaa atcttgtaac
     4261 ttcttctgcc aaacggcgtt gtgcttcacg tttctcaggt tctgtctcta cttttttcgc
     4321 taagtcttcg atttcttctt gagacaagaa agtaaagaat ttcaagtatt tcactacatc
     4381 gcgatcatct tgattcaacc agaattggta gaactcaaat ggtgaagttt tcttcggatc
     4441 aagccaaacg gcaccgcctg cagtttttcc gaatttcgtt ccgtcagcct tcagcatcaa
     4501 tgggatcgtt aaaccgaacg cttctgcttc tggtccttct aattttcgga ttaggtctaa
     4561 tccagctgtg atatttcccc attggtctgc tccaccgatt tgcaattgca catcgtatgt
     4621 tttatgcaga tgcaaaaagt cgatagattg caggatttgg taagtaaact ctgtaaatga
     4681 gattcctact tccaaacggc tggcaacgat atcttttgct aacatcgtgt tgatgttgaa
     4741 gtttttaccg tagtctctca aaaattcaag taaagagatt tttgacaacc agtcgtagtt
     4801 gttcacaaat gtgatatttg catctttacc aaacaatttt ctcatttgat tggaaagtgc
     4861 gtccacgtta tgttgcactt gttccatcgt ttgcaacaca cgttctgttt tgcggccgct
     4921 tgggtcgccg atcgttcctg ttccgccgcc aatcagaata tatggatgat ggcctgccaa
     4981 ttggaatctt ttcatcatca taaatggaat caaatgtccg atatgcatcg aatcaccagt
     5041 tggatcaacg ccgcaataaa gtgaaatgct cttttcttca acgagctcgc gaagtctttc
     5101 ttcgtttgtt tgctgattaa tggcgtcgcg ccaagttaat tcatcaataa tattcatttt
     5161 actgacctcc gtgtagtttt tttatgaaag caggaacctg ctagcatgtg taattaatta
     5221 tttcttcagg ataggatagg aaataaaaaa agtcccttgg catataagcc aagggacgaa
     5281 atctcgcggt accacccaat ttgtatgtct agatatccaa catacctctc gaacatttaa
     5341 cgctgtcgcg tggcaatcac tgccaaagac tcctgaaatg taattcgctt taaagcatgt
     5401 actggtttgc agcgaccacc agctttctga aacattggct ttaacaacta cttcgtttcg
     5461 atcttcgtct tgttattatt aatatgtgtc tatcatagag cgcaactttt tctttgtcaa
     5521 cagaaaaagg atattttttt taaattcctc attttttctt ttttgaatcc gctctaattc
     5581 cgaacatttt attttcaatt attgttaaaa gaaataactt tttctgtatt ttttctgcaa
     5641 tttatcgaga agtcacttta ctttgcctct tattctttct tcgttacaat aaggaatggg
     5701 acaagtaaaa aaatgaaaaa gcaagggacg aggtatatgg aaaaaaagca aaaaattatt
     5761 ttaggagcca cttctgcttt aactatcgtt attttaattc taagtttgtt ttttgtcatc
     5821 cgatcatcta caaaaaaaga accaatcatt cctgaaaaaa aaataacaga aaaagcaaaa
     5881 gaaccgacag atgataagca acaactagtt actcaagcaa aaaatctggc tcaaagctac
     5941 gattatgacc aagcgattgc gttattggaa aaagatagta agaacggatc tactgaaaca
     6001 caacagcttc ttcaaacact aaaaaaggag aaagaacaac tgatcgactg gtctgatcct
     6061 actcagatct ctcatgtctt tttccacagc ttgatcgtgg acccgcaaaa agccttccac
     6121 tctcaacagg cacaaggata caaagattat atggtgactg ttgaagaatt caaccgttcg
     6181 atcgaacaac tttatcaaaa tgattttgtt ttagttaatt tgaatgattt gatccaaaaa
     6241 gacgaacaag gaaatctttc ctttaacggg cttgcgctac ctgaaggaaa aaaaccattg
     6301 gttctttcac aagatgatgt cagctattat gaatatatgg ataattccgg ttttcctagc
     6361 cgattggtcg tatcaaataa caatgaaatc aaaaatgtct ataaagagaa agataaagaa
     6421 gaaatcggtg actttgacat ggttcctctg atcgatgcct ttgtcaagaa acatcctgat
     6481 ttttcttatc gaggcgcaaa aggtaccttg gccctgacag gttacaacgg agttttaggt
     6541 tatcgaacat caaaatctca atatggagac aatgaaaaaa caaaaaaaga gattaaagaa
     6601 gctaaaaaag tggcggaaca gttgaagaaa gacggctgga gctttgcttc ccatacatgg
     6661 ggtcacttga atatgactca agcttcacta gaagatgtaa aaaaagacaa tgaattgtgg
     6721 cagcaagaag ttgcacctat cctaggaaaa acaaatattc tgatttatcc atttggtgca
     6781 gacatcagcg actggcagcc ttattcagca gaaaatcaaa aatttgctta cttgaagagt
     6841 caaggtttcg atattttctg taatgtcgat gcttctacac cagcttgggg acaattaggt
     6901 acggatttct atcgaaatgc tcggatcaat atcgatggca ttcgttttca atctgattta
     6961 gacggaaaaa atcctattct tgatccattc atcaatgtcc atgatgtcta tgacaaagaa
     7021 gcacgcgaat ctgcttgatt ttacgtcatt tatgaaccaa aaaagccgaa ctgacatttt
     7081 atcgtcagtt tcggcttttt tatgctttat ttcttcttcg gtgcgattcc cttgatcagg
     7141 acttctgtcc attctgctgt atatggaagc agttttgcgt atatctccgg cttagaaatt
     7201 ccttctacca ttgcttgaaa atagaggatc aagaactcat ccgaatattt caaatccact
     7261 tttccttctt tccgccctcg atggaaaaga tcaagcatga tactgaaact ttcttgcgta
     7321 tacgcatcca tcgcgtcaga aaattctttt ttttcttttt ttgtatagta tgtcatcaaa
     7381 tcgatataaa attgtttgtt cactcgattg agataacgga ttttgttttc actcatggca
     7441 atcagtgttt cttcaaatgg aagattttcc gcaatcaacg ctttcgcttc ttgccctaaa
     7501 tcattcataa atgcaaaaaa tacttcataa atcagccctt ccttgctgcc aaaatattta
     7561 aaaatcgtcg ctttacttac ctgagcgttc tcagctacct tatccattgt cactccagcg
     7621 gttcctatgt ctgtgttcat caagtcaaaa gctgcttgta aaatctcttt ctttttctct
     7681 tgtgctctct tttcaaaacc gttcatttgt agagcctccc gtaattttaa acttttataa
     7741 tatatatagt tcaaatttat tctgaggttt attataacta tctattgaga aagtatcaag
     7801 ctagcaattc cttgtttatg aattcattga cagaaattta taaaaagaat attatgtact
     7861 aaaataataa aaaaaagttt tataaaaagg tataaaacct ttttattaaa ctatttaatc
     7921 ttgtttagta tatattttta gaaaaaggag tggggttttt atggcagaaa tcgtcaaagt
     7981 cacacatttg aaaaagagct ttggtcgttt cgaagcttta aaagatgtct ctttcaccgt
     8041 acattcaggt gaagtcgttg gatttatcgg accaaatggt tctggaaaat ccacgacgat
     8101 tcggacactt ttagggatta taaaaaaaga cggcggaacg gcaacgattt ttgggcaaga
     8161 tgtatgggaa gatagtttat ctatccatga acgtctttct tatgttccag gcgatatctc
     8221 tttgtgggga aatttgactg gaggagcgat catcgatctc ttcatgaagc ttcatggaaa
     8281 agggagtgct caaaaaaaag atgaactgat tcaacgtttc tctcttgatc ctaagaaaaa
     8341 agcaaaaaac tattcaaaag gaaatcgcca aaaagtgggc ttgattgctg ctttggctgt
     8401 tgattcggat ctctatttat ttgatgagcc tacttctggt ttagatcctt tgatggaaac
     8461 gattttccaa gaagaagttg aaaaattgaa agaacagggc aaatccatcc tactttcttc
     8521 tcatattctc agtgaagtcg agcgactagc ggataaagtc gtgatcatac gcgaaggaac
     8581 actcgatgaa gaaggaacac tcgatgaatt gcgtcatttg actcgttcga ccatcactat
     8641 agaaacagaa gcagagaata gtcacttagc acaattgaac ggtgtccatg actttgtgca
     8701 aaaaggtcac ctcgctcaat ttgctgctga taacgaagct ttcgatgtga ttttagctga
     8761 agcgtccaaa ttaggtgtga aaaaatttga atctattcca ccgactcttg aggatttatt
     8821 catgagacat tatgaaggat gaggaggaag cgaaatgact gataaatttt cacgctggtc
     8881 cacccttttt tctcaaaacc ttagccgtga ctggaaaaag atcctgatat ggctagtcgg
     8941 tgtcactgct ttttctggtg gttttgtccc tgcgtttgaa gaattgactt ccggacaagg
     9001 attagctgga ttatacgaaa ccttgcaaaa cccggcaatg attgcaatgg tcggaccaac
     9061 tccagcttcg aatgctgctg agtatacttt aggagcgatg tatgcaaatg aaatgttgct
     9121 tttttgcagt ttgtttgctg ctgtgatctc tgttttacac gtggtgagcc aaacgagaaa
     9181 aaaagaagaa cttggtctga ttgaacttat tcgttccttt cgagtcggac gtcaagcaaa
     9241 ctctttagct gtcatcgctg aaagtattct gatcaatttg cttttagcaa tatcgatcag
     9301 ctgtacgatg atttttttcc aagcggattc gatcactgca gaaggtgctt ggctttttgg
     9361 gctatctgta ggtagtatgg ggattttggg gagtgccgtt gcactgtttg ctgcacaact
     9421 gatgccaagt tcagccagtt cgaatggtct gtctttagcg tttttaggtg gactttacct
     9481 tctacgagca ataacagatg tagctgattc ctccctttcg atgtggaatc ctttaggctg
     9541 gtcttatttg acctatccat ttacaactaa caactggatt cctttgcttt atttgttttt
     9601 gttcagtcta atcttgataa tcagttcatt tgttttagag gaacatcgag atttgaacac
     9661 cggctatatc cccgaacgtg aaggaaaacc gtatgctaaa cgttctcttt tatccttgcg
     9721 tggtttatta ttctatctaa ataaagggat gacaatcagt tggcttatca cttttggttt
     9781 gatgggggcg gcatacggct ctatctacgg gaatatgcaa cagtttttag aaagtaacga
     9841 cttaatgaaa cagatgttta tccaatctgg cgtctcaatt gaaaaaaact ttacaagcac
     9901 gatcatggta gtcttgattt gtctagctgc tattttacca attgctagca tcaatcgttt
     9961 atttacagaa gaaacccacg gacgtatgaa tcagctgttc gcaacaaaaa tttctaggaa
    10021 ccaactttat tggaccaata tgttactagc tattctattt gctatattgg caatcctgat
    10081 tagttctggt gcactagggc tttctgcttt ggcttcgatg aaggatgcga aagacatgga
    10141 tctattgatg tttcttaaag ccgggttcaa tttcctgcct gccgttttag tgtttatcgg
    10201 aattagtggc tttctattcg gatggcttcc tcgaatcggt aaacttgctt atatctactt
    10261 agcttactcc tttgcactca attactttgg cggaattttg gatttaccag aatggttttc
    10321 caaaacagct gtccctagct gggttccacg gatgccaaac gattcttttg atctttccgt
    10381 gttccttacg ttatcatgta tcagccttgc actgttcgtc cttggttcta ttggttatag
    10441 gcgaagagac ttactagaag gataataaaa aagcatgtac aatttcatgc tagcctccaa
    10501 atctgggtca aaaatccaac atttggaggt cattttttta tttacaagtc ttctaactgc
    10561 tctttatcaa tgatccagac ttctcgattc tttcttttta cataaccatt ctcctctaat
    10621 aatttaaatt ttctagataa agtttcgggg gtcgtaccga taaatgcagc aagttctttc
    10681 attttcattg gcaggaaaaa gtgatccttc cctgtcgctt tagctaagtc aagcagatag
    10741 acagcgactc gttcttctac tttttccatc atcaaaaaag ttgtctgctg ctgtactttt
    10801 gttaatttct caacgttgat tgctaaaagt ttcagactaa gggcgggata atgcagtaag
    10861 agttccgaga aatctttttg tctcaatatg caaatttccg ttttttctag tgcttcgcca
    10921 aataaagact catttggaac gcctagcaac tggctctctc cctcatatcc gcccggctct
    10981 attactcgta aaagctgttc ctttccgcta gcagataatt gatacacttt catactgccg
    11041 gaggccacga tcactaattg aggttctcca ttcggcgcaa gaatctgttc tcctttttcc
    11101 acatagtgat gtttgacaag tgcgtgtact ttttcttgat cttgctgtac taagtgattg
    11161 aacaaaggaa caaatgaaac acataaatga tcatgactca taatctctcc tccttctaaa
    11221 cagctatttc taataaagaa acataacttc ccttattcca actgataatt ttcttttatc
    11281 atagcataaa cgtcaagcga accagatacc agcaaataga gtggatttct ttttgtccct
    11341 tgctttattt tccttctttt gagaccttaa gtaattgatt cctatcaatt ttttaaatat
    11401 ttactttttg aataatcaaa aacaaacctt cactcgcaag ccgagagtaa ggtttgtttt
    11461 tcgcattgct tatttcgtgt tgtctattga aatttttccg cacctagctt ttgatatagt
    11521 ggtgctagtt cttgtaaggt ttcagcggtt atttgctcaa cgtgttcgat ttcttgcgga
    11581 tagaagaata gtttacccat ttgaaaggtt cggtctctca tcgctttttt caactcttct
    11641 tgtttctttg tatcggacaa atagtcagac aaagctaagt ggtcgtcaag ttcatgttct
    11701 ggttgcggcc atatgtaata atccttgata tcgactgttt tgctccactc tttcagtatc
    11761 gcaagcaact ggttatacgc tgcaatgcta ccatatcgtt cttcgctttt ataatgttgg
    11821 tacatcaaat agatttggta ttgtttttga ttcaacaaaa ctgctagaca ggcattctcg
    11881 tcttgacgag attcgcttcg gtacgcgctc caaaaatgac tgcgtaaatt ccagccattc
    11941 gtccagcttt cgattttagg tttgctcatg ccgtacatat caggcaaaag tgcagctgtc
    12001 tggagctgaa tctctttcca tttttgccag tgttctttat attctttctt gatttgttca
    12061 atcttatctg ttggatggct ctctttgagc tgtttgaatg cgtagattgg tcgatcaaac
    12121 aactgataat ctgattttcc aagttccatt gtttcgcctc tttccgttat cttttgtatt
    12181 ctacctgaat tttgcgatat ggacaaatag aggttgtgaa aaagctgttc tgcatcaagt
    12241 cataagaaca gccaaacaaa aaactgcgat gagcatcacc gcagttttat tgaacttaag
    12301 gttgattgat cacatctaaa agcgttgaaa ataaaatggc actagaagca gctcctgggt
    12361 cgatatgtcc gattgcacgc tctcctagat aggaagctcg tcctttttta gctaccaaga
    12421 ctttggtgtg ttcttttgcc tggtcaatga tttcttttgt taaattccct gccttcaatg
    12481 cctctgtgac tggcagccaa acatctaaca tcgttttatc gtcagcttct gcctttcctc
    12541 ggctttgaat acccgctgtt ccctgctcga tcacttcgcc taatttttct tgagaatcaa
    12601 tagaatcgac ctcttttgtc gctttcatca tgttcatgaa tgcagatccg tataacggac
    12661 cagaagcccc accgactttc gatatcatcg ccatagagaa tactttgaat gtatcgctga
    12721 ttgtttcagg atgatcggct tgaaaagctt cttcataagc tgaaacccct cttcccatgt
    12781 tatttccatg gtctccatcg ccaatcgggg tatctagatc actgagatat tgtttgttct
    12841 gattgattgc ctctgcaaat tgcgtgagcc attcttggat ttcttgaacg gttagtttca
    12901 tattatcacc cttttatctt gagatttttt accatgaaat cgtctgtaca ttgctttcta
    12961 aagaatcttt ccattgtgtc tccgtcaagt cgatcagtgt tagagaaaga ccttgcatat
    13021 ctagtgaggt cataaaatta ccgacttttc ggaaaactac attgacgcct ctttcttcca
    13081 acagagctaa aacatcattc atgaacacga actgttccat caaaggcgtc ccgcccattc
    13141 cgttgactag tacacctgct tcttttggta aattcgagta atcatctaaa atcttagtaa
    13201 caagttcctt tgccagtact ttagaaggct gcatcttttc tcgacgatag cctggctcac
    13261 cgtggatacc aacaccatac tcgatctcat cttctcctag ttcgaatcct ggtttcccta
    13321 cttctggtac agttgctgct cgaagcgcta gaccgatcgt cttagttgcc tgtacgacct
    13381 tttctcccag ttctttcaac tcagctaggg aagcaccgtt tcttgctgca tcgcccacga
    13441 ttttgtgtac aaggacagta cctgcaactc cgcgttttcc agcagtatac gtactatttt
    13501 caacggcgat atcatcatct acgatcacac tttctacttc aatatcgtcc atagcagcta
    13561 attcctttgc catatcgaag ttcaatgcat cccctgtata attcttaacg atcagcaaaa
    13621 ctccttttcc actatcggct tccttaatag ccgtctgaat ctgatctgga gttggagaag
    13681 taaacacatc accaagcacc gctgcactta acatcccttc ccctacaaac ccggcatggg
    13741 atggttcatg tccgcttcct ccaccagaaa ccaaaccaac ttgttccgct ttctgattct
    13801 tggctacaac acgggaagat tctacacgat gaacaagttc tggatagctt tttactaatc
    13861 cttccagcat ttcttcgaca atattgcttg gatcattcat gatttttttc aatttattcc
    13921 catcctttct ttccggcatt ttgtgcttct gttaagattt gctgagtatc atctgttata
    13981 ccggcagtga tggctgctgc aaaagctcct tccactaaag gcgcatccac cagatgataa
    14041 cgttgctgct gctcttcttc caacatgtct tttgccagtt ccgagttcaa taccgcgcta
    14101 ccgatatccg caaaaacaaa ataactagct gcatcgcttg attcattgac tgcttctacg
    14161 attttcatcg ggtctgatcc gatctcgcca tttattccgc cgagagaaaa aatttgcacc
    14221 tcttcggatt tttgcatctg ctcaatcatt tctttaatac catctgttac tttttgacta
    14281 tgagaaataa gcaaaatact ttttttcaca agaatcttcc tttcttttac atagttgcta
    14341 acgattggtt tcgctttcat taatgaacaa ttcaagtata taataaattt ctaattttgg
    14401 gaaaatatgt gtagtgcttc ttgaagtttg ttatacttta attaaaagag aggagtgatc
    14461 gaatgattac aacaacaacg aacagtgtag agggaaaagc cgtagtagct tataaaggga
    14521 tcgtttttgg tgaggtcatt actgggatcc atgcatttaa agacttggag gcggggttgc
    14581 gaaatatctt tggcggccgc tcaaaaagct atgaaaacga actaatgggt gcaagagaag
    14641 aagcacttgc cgaaatggcc gaacgtgcaa aagcattagg agctgatgcg atcattggcg
    14701 taaaaatgga ctatgaagta ttaggcagcg acaatggcat gctgatggtc acatgtagtg
    14761 gaacagctgt ctccacgaga taagtagggg acatctgttt taataactaa agagagatgg
    14821 gacatgtagt ggcactcaag aattagattt ttcagtctaa cttcgaggta ctctaccttc
    14881 ccatcctctc ttttttattt ctttttgcgg atgattccgt aagctgctgc gactaacaca
    14941 cccgcccctg ctaaggaata actgacagaa gctgtttttt catttgtttt tggcaaagtc
    15001 tgacttgttg atttggatgg ctctgtcgtt tgctgaactg tttctgtcgt gcttccagag
    15061 gtcactgatt tttctcctgc cgaatgcaaa atatctttta ttcgttggaa actagctgct
    15121 aagtcagctt tttttgcttc aaaatcatta gcaactgttt gtgcttcgct gatctttccg
    15181 tggattgctt gactggccgc tgtgatatcc gcttgagttt gacttagctt tccagaagct
    15241 gtttgagcaa cctgatttaa ttgctgattg aattcttttg cttgttggat cttcccgtca
    15301 agatctgttt ggacagcttc cgcttttgct ttcgcttcgg caagcttttt ctcaagttgt
    15361 gcacggtcat ttcccacttt atttttaaga tcagctaaat cttgatcgat tgctgcttgg
    15421 tcttctttca atttgttttt tgcagcttct aatgcttctt cgagttcttt tcttttattt
    15481 tccaagtctt gcaaatgatc gatttggtca gaagaggtag aactatttat tgatgtatct
    15541 tctgaagatg aaatcgtttc tcctgaatta tctgtcggta cattggaagt catttctgtt
    15601 tccgaggcac cgttttcagc accagaagag cttatggttg ttgaaggttc tgtttgagca
    15661 ggttcagaag tttccgcaaa agctgtctgt cccaataaga aaatactgga aacagcaatt
    15721 ggccagatta acggcttcat tctttttttc atcacttttc ccatccttac tactttttaa
    15781 ctaatttctt attataagca aaaatgtttg gaagaaccat aaacacaaca ggctgtttgt
    15841 ctaaaaaacg gtgcatcttt tatttttttg tacgttccgg gcttttccat gtcccgcttc
    15901 cataacctaa aatcgttttg actgctggaa tgaaagtcgt cacgatcgtt atcgcgttca
    15961 ctatccagaa caaaagcata tatagtggtg cgaaaagaag gtatttcaat tttcttcgtc
    16021 gatcatctac aatcagcgaa gctagcaact ggaaaaatcc tgcgaccatt tcaaagcaga
    16081 tgaacacaaa actgaatgta aaagtaatat aaatctgttc gtagtttcct tgatatacat
    16141 aatgcccgat taatccagca aaaagaacta cggaaataca aaagaatatt gaccagacaa
    16201 tactcaatgt ttgatcaatg aagatgatcg ttcttccaat atgtttaaaa ggatggagca
    16261 tcactttttt gaaattcgtc agccagactt ctgttccacc ttttgcccaa cgttttctgt
    16321 gtcgatatag catcttcaac gtcacaggta cttccatgaa aaagataatc tcaggagcaa
    16381 aaacagataa ccagtcattt aactgatgat cccaagcaat actgatgtct tctgtcgctc
    16441 gatcttgtct gaatccgccc acatcgatca aggcttcttt tcgatacatc gtatttgctc
    16501 cactgtacgc ataaagacca ccgaaaacag ctgactgtgt tcgtttaatg atgcccacga
    16561 tacttgagaa ttcaaccgtt tgagattttg caatcaattt ggtacgattt tggacatcca
    16621 tatttgcagt gaccgcagca atatgtcttg caccagggcg aatgaaataa ttcacatacc
    16681 taatcagtgc atctggctcc ggtaccgtgt ctgcatcatt gcttaaaatc aatttccctt
    16741 ttgcaaaggc aagtccgata ttaaacgcgt gggcttttcc tttatttttt tcgatccgaa
    16801 ccacacgaag attagcgtat tttttcatca gtctagctaa tatttctggt gtttggtccg
    16861 ttgaaccatc gtctgtcact aatacctcat agttgtgata attcaatttc gtcatcaaat
    16921 actcgattgt atattcgatc acaatttctt cattatgggc tggcaccatg atcgtgatga
    16981 acggttcgac actcaaggga acatctaccc attctttttg cttatgtttg tataaaaaca
    17041 cataacacca gacaccaata aaccatacaa atccgcctaa aatcggataa gaaacgagaa
    17101 aaaaatacat aatagacaaa caagtatcta agaataaatt acctgtatgg gtgattgaga
    17161 tcatttcagt tccaccccat tttctttata caaatctgca atgaatgtcg tatctagatt
    17221 tttctcttcg gagacagaat aaaaacggac cgtttctctc tcttcttttg ttccaaaacg
    17281 ttccgtatac acttcttcaa gtaattcttg tctttttttc aatttttcat cttcatattc
    17341 aaaagattta tttacttttt tgtatagatt tcgattgttc cacctagtca atacaaatga
    17401 ggtaatcagg aaactgaaaa aaatcaatac aaaaaagccg attaagaaat acagcatttt
    17461 cttttctgat aaaaaagcgt acaaggaaaa atccttggct ctttctggtc tcgttaatgg
    17521 gaaaaagacc catataaaag gaagaacaac gatcatccat cctaaaagag ccactaacgt
    17581 ttgccaaatc tttaaccagt aattaccttt tgaaaaatac ttatctttca ccaaaattga
    17641 tgcaacttct tctcttgtta cttttttcat atcctcacct cacgtttttt tgttacgacg
    17701 taggagttta ccatacattt catttctttt cacataaagt gttcctaaat ttttcctaag
    17761 aaaaagaaca aaacatttct catcagcaaa tgaaaaatat tttgttcttt ttatcagttg
    17821 ttctttttat tttttatctc ttaattatgt tgctctttcc aatacgacaa tgcttttcat
    17881 tcctctagat atcgccgtgt acatttgtct gcgtcttctt tgctcatctc catcgttttc
    17941 aaatggatat aagattacat gatcaaattc cagtcctttt gctagactca aaggaatgat
    18001 ttggcagttt tctaatccat atgaattttt tttaatcgat tcttgtagcg tttgggtttc
    18061 ctcttctgtt tgggtgataa ctgccgcttt ttctcctttt agagaaacca aaatctcagc
    18121 tagtattttc aacaattctt cagaggatcg aaaagagcgg tattcgggtt cttttccttg
    18181 cggtcggatc gatacgatgt cgatcttctc ttgatccaca gcataggttt tgaaaagctc
    18241 tgtgattgct ccgctagaac ggtaactatt tctaagatca taccgatgga tcggcagatg
    18301 gtagtcgtcg aaacaacgca taatatcagc aaaagtagtg gaagaattaa agattgcctg
    18361 attctcgtca cctactaaag taaagtgagt ttttggaaat aattcgatca atagacctaa
    18421 ttgtgccagg gtataatctt gtacttcatc aatcaataga tagcgaaatg ctggtacatt
    18481 taccttttca acaagtaaat gacgaatagc taatataatg actgcttcat caacagtacg
    18541 tgtgggttgc caagcataag ctgagccata tcgtttttca taaattcttt caaacaactg
    18601 atgctcatcc acccatgcca tttcttcgat ttgtctggtt atttttcgat attttttttg
    18661 taaaagtttc cttgcataag ctacaatact ttgttccgaa tcatcagaaa tcaatttacc
    18721 gaataattcc aactgcctat cttctgtcaa cgagagtacc tgattctgca cagcaggact
    18781 ttttgcttgt ttcaaaagat gattcttcca ttcgctcatc agtgcctttt tcgttgcttg
    18841 aagcctatcg atcaatttag gatgagcagg aactttctca tatatttttt cgatcgtttt
    18901 tttagaaagg actgtttttc catttttagt aagtccacgg ataaaattcg gatgatctaa
    18961 aaacaaagga tctgattgtt ttagattatc gataaacttt ttgctacgca aacgttctgt
    19021 ctgctccgat acattttctc ccgtgatacg tttgaaataa gcctcttcac cttctatttc
    19081 ctctgctgaa agctgtgaaa ccagctgtat gatggttaga ttcagtggat ttctttcacc
    19141 taatgatggt aggacattcg aaatatagtc gataaaccga tgattaggtg atagaatcag
    19201 caagtcatcg gatgtcatcg tatctcgata taaatagagc agatacgcaa tacgctgcat
    19261 gatagcagag gttttaccac ttcctgctac gccatttacc aagatatttt gacttttcac
    19321 atcccgaatg attgtgtttt gttccgattg gatcgtagca gtgatagcct tcatttcatt
    19381 ggtctcatct tggcctaaga cttctaataa tacgtcatct tgaatagcta cagacgtatc
    19441 aaaaaacttg accaaacgat ctctttccaa aagaaattgt cgtctttctt taataaccgt
    19501 atcgatttta ttttgacgaa ccgtataaga agatggacca atcatgttat tgtaaaaaag
    19561 ttcggcaatt ggtgaacgcc aatcataaac aagattttca tctgcatcat ctgtgaaatt
    19621 tgctgtaccg atataaaagg attcttttgg ctcattatcc agaaagtcta caacgacttt
    19681 tccaaagtag ggacttttca ataaacgttc gatctttgct agctgatttt ctgcgttttt
    19741 ctgtttgata ttcatctgat cgatttctct atttttcatt tcaatcatcg aaaaagtatc
    19801 caggttatct aagtaactgt caaaattcaa tcgaagctcg ccagccattt ctttcaacga
    19861 ctggtttcct tctatttttg ccgtatccat cgattcccgc agttcgtttt ttttatcaat
    19921 tagcttttga tacacgttct tcagatatgc ttcttctaac tgtttttgtg tgttgaccat
    19981 acacattctc ctcttttttt aaagtggtgg aaccgattag tttacctctt ttaagagtcg
    20041 aatgcaagct ttttaacgag tatcatttgt taggatatat cagttcttca ggtcggacag
    20101 tttgatataa agaaaatgca ccatcaaggt tttttacgtg gtagccagac tgcttcaaga
    20161 ttctttccgc tagatagcta cgtaatccgc tatgacagct gacgatatat tcttgttggc
    20221 tgtctaattc atttaatcgg tcccgaagtt cattcaaagg gatatgtttg gcttccttga
    20281 atttgccctt ttccaattct tctgctgttc gcacatctaa taaaattttt ccttttgcta
    20341 gttctgtcgg caattcatgc cattgtacgg tttcactaag cccttctgca atgttcattg
    20401 ctgcatatcc tagcatgttt actggatctt tggctgagcc aaatggcggt gcatacgtca
    20461 attctaattc cggtaaatcg aagatcgtca aatgcccttt gattgctgtt gctaaaatat
    20521 cgatccgttt atccacacct tttgccccaa caccttgtgc accataaatc tcgccagtct
    20581 ctggatggaa gatcaacttc agtaaaatat ctgttgcttc tggataatag cttgcatgat
    20641 cttttcctga tacatgaatg acttcaaaag acagttcgtt ttctttggct gttctttcac
    20701 ttaaaccggt ggatgcggca gtcattccaa acgttcgtat aattgctgtt ccaataccgc
    20761 cttgatttct tcgagaaatt ccggaaatcg tgtccgcaac ttgtctacct tgacgattgg
    20821 ctggtgaagc aagagaaata agtgcatctt ttccagtgat ttgctgtttt acaacgatag
    20881 catcccccac cgcataaata tcaggaatat tcgtttgata acgttcgtct actaggatac
    20941 ccccgcgtat gcctaattcg attccagcgg tcactgctag ctggttatca ggacgaacac
    21001 caatggataa aataactaaa tcagcaggga tggtacgccc atcatccagt cgcaatcgtt
    21061 tcccgtggtc ttcaaatcca gcgacagcat gagaagtaat cacttctact ccttgatgag
    21121 acaattcttt ttctataaaa gctgccattt cttcatccag tgttggaaga atatgtggtg
    21181 cttgttcgat caccatgact tctaaacctc ttctttttag gttttctgcc atttccaatc
    21241 cgatgaatcc tgcaccaacg atcacggcac gctttggctg tttttctaat gcatgcatca
    21301 ctttatcgat atctggtaca tttctaatag aaaaaacatt gtcggcttct gttatccctg
    21361 gaatcgatgg aacaactggt tttgcaccag gagataaaac caatgcatcg tactgttcaa
    21421 tgtgtttttg accctcatgt acgacttcta ccgttttgtt ttcgggaaag atggctgtca
    21481 cttcatgatt tggacgcaca tctaaacaaa aacgagcgga taatgattct ggcgtttgga
    21541 caagaagatt ttcccgttca ctgatttctc ccgaaagata ataaggcaag ccgcaatttg
    21601 caaaagaaac atacggtcct ttttcaaaaa caacgatttc tgcatcttcc attaatcggc
    21661 gaagccgtgt agcagcagac attccacctg ctacacctcc gacaataacg attttcatct
    21721 tatttccctc ctactgttcg atcaaaccat tgattcatgc caccacgtac attcactaca
    21781 tcataaccag atttctttaa ttctttagct gcttgtttac tcctcatccc tgattgacaa
    21841 atcacataga cggtcttttc tttgtctcca tcatatctgt ttatactttg taatggaaca
    21901 tttttagctc cttttatatg cccgccccgg tattctgcag gtgttctaac atcaagtaac
    21961 gctggatttt ccaaaagctt ttcctttaat tctgggactg ttatcgattt tattgattga
    22021 aatagcaaat tcattttctg cacctcattt acatttttat aaatacctca tggggtatat
    22081 taaacaggag ctttattaat atgtcaacca gaatgactct tcattttttt cactactttt
    22141 tatatttgca taaaataccg ataaggggta ttatctaatt ataaaaatag aggagaatgt
    22201 gttatggaga ttgataataa aaatatcctg aaccgtttga aacgtacaga gggacaaatt
    22261 cgtggtatcc aaaaaatgat cgaagacgaa aaagaatgta tggatgtcat cactcaatta
    22321 agcgctgttc gttctagtat tgatcgcgta atgggcatga tcgttgcaga taatctgaaa
    22381 aattgctttg agaaacctga tagtaatcca gaagaacaag cggctaaact agaacaagcg
    22441 atcaagatga ttattaaaaa gtaaaggaat gatttcaatg aaagtcgttt tccatattga
    22501 tgaattagaa aaatggtcag aaacagggaa aaacgtaaaa aacctgataa aagcttctcc
    22561 agaaacgacg attgtcgtat ctgtaaatgg catcgcgatt accggttatc tagactctgc
    22621 caatgcagaa ttcttagatt tgcaaggagt cgtttttcac gcttgcgcca atgctatgcg
    22681 tgctaatcat atttcagaaa gttctttacc tgaacaagta atcgttgtac cagcaggtgt
    22741 ccttgattta gttgaactgc aatcccaagg ttatgcttat atcaagcctt agtcagtaga
    22801 ggttgcgaca gaagtgatca gcttcaagaa atttcggctt atttttcgaa gaagctactt
    22861 ctggaaaacc gtgaatcaaa ggttgtgaaa acgctgtcct gcatcaagta ataagaacag
    22921 ccaaacaaaa atagcttctc atatttttcg tttggttggg cttattaccg cagatgcaag
    22981 cttttgaaca ccgtttaagg aagaggttgt gaaatcagcg gtttgaccta agtattagag
    23041 aaaaaaacgg gaaaatagct cctcatattt tgccgttttt tgagctaata ccgaaggtca
    23101 gctgattgaa caccgtttaa ggaagagatt gtgaaaaagt cgcttagttt cgagtattaa
    23161 gaaaaatttt gtgaaaatgg atttctacat ttttgcataa atttggctta ataccgagaa
    23221 actggctttt gaataccgtt taaggaagag gttgtaaaat cagcggtttg acctgagtat
    23281 tagagaaaca aacggaaaaa tagctgctca tattttgccg ttttttgagc taataccgaa
    23341 ggtcagctga ttgaacaccg tttaccaaga ggttgtgagc ctaccattta actccgaatc
    23401 acaagaaata atttcaaaaa caacttctcc tgtttttggt tcggttggct tattatcgag
    23461 aagtagctac tgggagtcta tttatcaaaa aaaggaatgc gacataggtc acaccccttt
    23521 tttattttct ttgaaacatc tttcggtact cgacagcata caagacaaaa gattgtaaaa
    23581 gaccgtaagt gatgacggca aaaatgactc tcacccacag cgttggtaat tctgggaaaa
    23641 gcagcaaaag gatcatgcca acatagatga cagcagtcgc tactttgcca taccacttcg
    23701 ctccacttaa tttgatattt ttagatagcc cgattaatcc agctacaaac ataaagcctt
    23761 cttttatcaa gaatagacca aacaacagcc aaagccacgg tcgataccat gccatagaca
    23821 aaatcagaaa aagttgtgtc aatttatctg caaacggatc aagcaccttc cctaagtctg
    23881 ttacctgatt atatctccga gcaatgaccc cgtctagata atcagacaaa cctgagacaa
    23941 caatgaccgc tcctgctata taaaatgact gtctcagcac aaaataaaga taaatcggca
    24001 gcaaaaaaat acggaatatc gataaaagat tcggaatcgt ttgtatttct ttacgccagt
    24061 ctgtgcttaa tttcatttta tcgccctacc tcctcagcac tcttttcttt ttattttagc
    24121 ttacacgggg aataaaacca atgatttcac tgtttttatt tttctttaca gacactgata
    24181 ttatgagcta atttgagata atcacttgct gttttcatcg tttactcttc tttcttcctg
    24241 tcgtttgcgc atttctttta ctagtacttt atgagctttt tttgatcctc gctctaggtc
    24301 acgctgccgt ttacgtgttt tataatcgat aaacagactg tctaaatcgt aacctgtcgg
    24361 gtacagatct tctgctgaac gcaccagacg aacacgctga cgaggcacgt ggattatttt
    24421 tttgtctaaa tatacatcaa tcgtatcttc acctatatct tcataaacta acgcttcttt
    24481 ttggtattca ttgacaaata tccgatcacc ttttgcaaag agctgacgtt cttttttatt
    24541 ctccttccta tttgtaactg ctgtcttagg aagaaattct tttttctgtg tccgataggc
    24601 tttttccgcc aagtaacgct ctgcttgatg gatcaatttc atcgacatat ccattttatg
    24661 agcaatccac aaagcttggc tttctcctgt ttcttccaac ccgcaactga tatttaggac
    24721 gaagtgcttc ccgatcgaaa gccatagcag ccggcacaaa atcttcatga tctccggcga
    24781 atttcttgat ttctccataa tgggtcgtgg caatgatcaa tgccccttgc tcatacatag
    24841 attccatgat tgcgatcgct agtgcagccc cttcatttgg ctctgttcca ctgccaatct
    24901 catctaaaag taccaacgta ttccttttta tctttttcaa aatagcagcg atgttttgca
    24961 tatgaccaga aaatgtactc aacgcatttt ctaaattttg gtggtcaccg acatcgacga
    25021 aaatctcatc aaagacagca agctctgtcc cttcttttgc cggaacttgc ataccgaaca
    25081 tcgccatcaa agtcaataaa ccgactgtct tcaacacgac tgttttgcct ccggcatttg
    25141 ctccggtgat aatcaagcct cgatagtctt taccgatttc aacatccaat ggtaccgcat
    25201 gctcaggtaa aaatggatgt ctgccttgct tgataatgat atgttccgat ttattgattc
    25261 taggtgtgct tccattgatt tctcggctaa attttgcccg agcaaagatg atatctaaca
    25321 ccgtgatcgt ttcgatcaat aaatcgatca cttcttcgtt ttctgcgata gcaccagtca
    25381 atgccgccag gacttgatat tcttcactga tttcttcagc ttttaacaac tgatagtgtt
    25441 cattcaattt agaaatcaca gttggttcaa taaaaaccgt cgttctttta tttgattcat
    25501 cgataatcgt tccatctatt ttatttttat agctggcttt gataggaatc gtatagtatt
    25561 cgcctttttg aacaatcatt gcttcttgga tcatttcttt gtttttcgga tgacgcaaga
    25621 atttcagtaa ttttgactgg atttcttttt cgattagttg taattgtttg cgtactttac
    25681 gcaaattacg tgacgcgtcg tcactgactt tattattttt tattttctgg tcaatcaact
    25741 cttctacatt tatcaaatca ggaagatgtt tgctataagc aaacaacaag ggtgtctggt
    25801 attgattctt atcaaaaaac tttgtgatca tccgactgct tctaagaaaa tccgcatatt
    25861 cgatcaaatc ggttggctgc agaatcaacc cttttttgac ttgttctgtc agtgcatcga
    25921 tcctcggcaa ccccataaat ggaacatgct gactgctttc taagatcaag cgtgcttctc
    25981 ttgtttcttc ttgacgatcc aagacagttt gtaggtttgt cgagaccgtc atatcgctga
    26041 ttcgtttttt gctatagttt ccaattgctc ttgcttggat ttcctttttg atccgatcaa
    26101 attgtaattg actaatcatt tcgttgtcca tattctctcc ttttcttgaa gagatacctg
    26161 tcccaaaata aataagggcc tagagataaa taaaaggata gaacacagct taaaaaagtc
    26221 atgtcctatc cttattagaa tacaaagata ttgttttcct gacaggtacc gtttcataag
    26281 cacaccaaat aaactttgtt tattggctat tcgacttact gattagatac cagctacact
    26341 cacaaaacat accccattct tctaggtctt atttattttc cacttaacta tagcaagaca
    26401 cattttggtt gtcaaacttt agtatgtttt atagatttac accattaatg aatagacacc
    26461 taccgcgata attgctccga tcattggacc tgcgattggt acccatgaat atgcccaatc
    26521 tgaagttcct ttattagcta ttggcaatac cgcatgtgct aatcgaggac caaagtcccg
    26581 agcagggttg attgcatatc ctgttggccc tcctaatgaa agaccgatgg ctaagatcaa
    26641 tccacctaca gcgaatacgt tcgttccagg tgcaaattcg ttttgtccaa aagctagcaa
    26701 cccaagaact aatacaaatg taccaattaa ttctgtgatc acatttgctg gataattccg
    26761 tatagcagga cctgttgcaa acgttcctaa aatcgcgctt tcatctttcg ttgcattcca
    26821 atgtggcaaa taagaaagcc aaacaagaat ggcccctgca aaagctccta aaacttgcgc
    26881 aatgatgaaa ggaacgacaa gattccaact aattgcccct gtcatcgcca tagctagaga
    26941 gactgcagga ttcaaatgag ctgggcccat gaatccagaa atatagacag ccattgttac
    27001 agcgagtccc caaccaaatg cgatgacaat ccagccagaa gcctgtgctt tacttttgtt
    27061 taaattcaca gccgcacaca caccatctcc aagcaaaact aggatcagtg tcccaataaa
    27121 ctcccccatg atttgagtca tatcactgtt catttatttc tcccccttta gttcccgcag
    27181 atctgattct gcaatcaatg cttctaaacg tttagtctgt tgcgccttct cctcttctgt
    27241 ccattcaaaa tatccagcaa ttgcatcgat cacaggttgc ttgatctcat caagctgatc
    27301 tcgttcaaac aacagatgat ttgtacgacg aatgagataa tcgcctgggg ccaaaaccat
    27361 ttcttcttct aaaccataac gtaaccgagc tgactcagcg agactcaaac caggataagg
    27421 tgccatttct tttgctaatt caaagatacg tcgggcatta gtcccgtaaa aatcagcgat
    27481 ataagtagca tcttcttcct ctaaaccggc tgctactcct tcttttgcta attctgtcac
    27541 tgtttcttct aatttagttg gatcgaagtt tccacctgaa atctgatatt ttttagagtc
    27601 gatttctttc gtctctattc cgtattcttc ttttaataat tggcgtatca atcgcaaagc
    27661 tccttctgcc atcttacggt aatcggtgat tttcccacca gataaagtca gcaaaccatc
    27721 tggttctctt tctaaagaac tacctctgga aatcgtagaa ggtgcttttt catcacggct
    27781 gttttccaaa tggttcaaca cgtcttctac ttcagcacga gaaactttgt tttccttata
    27841 ttcacttact gtatcgacaa ctttattgaa gctcttgtct gaaatcgatc cattatctcc
    27901 accattgtaa tcagaaccag aattaccaat caacagtgga cgaagtcctg cccagcttgc
    27961 ttcgatatca ttcaatgtga tatttgcttc tggatagcga tgattgatca catccaatag
    28021 ataatctaca tcttcttgtg tgactttcgg atccgtaaaa tctccttggt aatccgtatc
    28081 tgtcgtacca aagtaagtct tgttttctct tggaatagca aaaaccatcc gcccatcttg
    28141 ctttcctgta tcgaagtatg tgggttgcgg tacaggcagt tttttcgcat ctacaactaa
    28201 atggatccct ttagttggac gcattttagg agagactgga cgcgtaaaat tcaagtttcg
    28261 tactttatct acccaaggac cactcgtatt gatcactaat tttgctttga tttcgatcac
    28321 ttcatctgtc agcaggtcac gagctttgac gccaacgatt tgatcgccat catataaaaa
    28381 gccaaccgct ttcattttac ttactagata agccccatct tcggcagcct ttttgatatt
    28441 atcaatcact aaacgggcat cattgttgcg gaaatctaga tagacacccg cgccttttag
    28501 cccttctttt ttcaaaaacg gttctctttc caatacttct tctggtgtca gcgtataatt
    28561 ctcatatttg gttcctgtca catttgccag tttgtcataa aggtccattg ctactttgac
    28621 cgagaacata ttgaaggttg ttgctccttc gccctcatag attggcaaaa gcattggatc
    28681 tggttttggg atgtgtgggg caatactttg tacgactgca cgttcaccaa ctgtgtcagc
    28741 tactacttcc acatcaaatg tcttcagata acgaataccg ccatgaacaa gtttggtcga
    28801 gcgagaggaa gtcccttctg caaaatcctg catttcgatc aatcctgttt tgattcctga
    28861 tgctgctgac tggactgcca caccggcacc agtgattccg ccaccgatga tcaacagatc
    28921 caattcttct tgctgcattt tttgaatgct atcttgtctt gtcttgtttg aaaacatatg
    28981 gatttcctcc ttattcaaat gcttgggtag cttttactgc ttttttccaa ccgttgtaaa
    29041 gtttttctcg gcgctcttcc tccatttgaa cttcaaatag cttgccagct tcataaaatt
    29101 cgcggatctc gtctgtatct ttccaataac cgacagctaa tcctgctaaa aatgctgccc
    29161 ctagcgccgt tgtttccaag ttttctgctc gttggatcgg tacattcaag atatctgttt
    29221 ggaattgcat cagatattca ttgtttgctg caccgccatc tactttcaat acaggaatct
    29281 tgattccagt gtcatcttgc atcgtatcga tgatatctct cacttgataa gcaatcgact
    29341 gtaaagtagc tttaatgata tcttcttttg tcgtaccacg tgtcaagcca aacatagccc
    29401 ctcgtgctgc ctgatcccaa taaggagcac ctagcccaac gaatgcagga acaacataaa
    29461 cctcatcttc gcttgtagag cgtttcgctg cgtcttctga atcgctagct ttttgcaaca
    29521 tttgaagtcc atctctcagc cattgaatcg aagaaccagc cacaaaaata cttccttcta
    29581 aagcatagta aacctttcca tttatgccgt aaccaattgt cgtcaataaa ttatttttgg
    29641 ataattgcgg tttttcaccg gtattcatga caataaatga acctgtacca taagtattct
    29701 tgaccatgcc tggttcgaat gccatttgtc cgaataatgc ggcttgctgg tctcctgcca
    29761 tccctgaaat tggtgcttcg cttccataaa aatgataacc ttgcgtataa ccataaactt
    29821 ctgagttaga agtgactttt ggtaacatca ctcgaggaat atttagtaaa tctaaaatct
    29881 cctgatccca atctagctga tggatattga acaacatcgt ccgactggca ttcgagtaat
    29941 cagtaacatg tgcttgtcca tcggtcagtt tccatactaa ccaagaatcg atcgttccaa
    30001 acatcaattc gcctttttca gctcgttctt gcgcgccttc tacatgatca agaatccagc
    30061 gtatcttcgt tgctgagaaa taggcatcga tcactaaccc tgttttttcg tggaaaaatt
    30121 cttgatagcc ttcatttttt aagttatctg caattccagc tgactgtctg gattgccaaa
    30181 caactgcatg atagattgga cgtcctgtat ctttttccca tattactgtt gtttcacgct
    30241 ggttcgttat gccaatccca gcaatctgat ttggtttgat ccctgattcg atgaacgctc
    30301 cggcaataac tgactgtaca gaattccaga tttcatttgc atcatgttcc acccaacttt
    30361 cttgcgggaa atattgcgtg aactcttttt gagaactgcc gatgtgtctt cctttcttgt
    30421 caaagataat tgctcgtgag ctagttgtac cttggtcaat cgccatgata tacgttgatt
    30481 ctgtcattgt gattccctcc attatatgca aacgctttct ttaactactc ttatcatact
    30541 actgttttaa aaaaagaaac tgtcaaaatt ttattctttt tttctttttt tgacagtttt
    30601 ttattatgaa gctatttttt aatcaattct tttctttttt cagcgtctct attcttcttt
    30661 tcaatcgaat aatgtcgtaa ggtgacgcaa attctgacag ataatattca cactgttttt
    30721 tgtttctctg gcaaaatgtg atcaccaaat catattcttt accttcttca taacttccaa
    30781 tctcaatacc gccgattccc ctcagttctc tgatcagata ttgttgaaaa gcaatacgat
    30841 aaatcggcag actttctaaa tcgattccaa tcactactgg ttttgcaata taaaaatcga
    30901 tcatcaaaag aacattggca tactggatca tcaggtaact aagctcacta tcttcagctc
    30961 ttttcctcgg caattgctgc accgctgttt cctgtaattt cgccagtaac tgtgttaagg
    31021 aatgcccgag cattttctgc tgctgttcca aaagccgatc acgctcatag acttcgatct
    31081 ttccaacaaa gaaaaaccat tcattgttga tctgggaaat ttggtagcct actgcctttt
    31141 cttctttgat tttcaaacga cgaggacgat aatgccataa catcgtttcc cgaatgtaag
    31201 tatctaaaac agcggttggt aactttttgc tccgtgtcaa atcatactga taaaatattt
    31261 cttcgtctac tatcgaaaaa gaaacaaaaa agctgtaaaa catcattgtt tcgtatacat
    31321 tcagttctgc tgctgttcga ctaagatgca tcacgatgat tggatcgatt gcttgataaa
    31381 gccggtccga ctgatagagt aatttctttt ctttcaaagt tgcgtacgta cttttttcat
    31441 tcaatagtct ttttttcgta atcccgagcc agcaagcaat ctgtgcttct gctgatgccg
    31501 taaacgttgt ttctaataca cggtccaatc ctagaatgaa cggtcttttt tctggtgtat
    31561 tttgcaaaaa aagcggtcgc tgatcttccg ggatatattg gaatagttca taataaaaat
    31621 atcgtatctg tagctcttct ccgtataatt gaccgttttt gatttgtaat ccaaattcct
    31681 ctaagagctg gttcaattct ttgatctttc gaaaaacaga agactcactg atattaaacg
    31741 ctgtcgctaa tcgaacgatg gatacttgct gatgttctaa taaatagacg agcatcttaa
    31801 acttcaagct ttcctgcaat aaaaacaata gaattttttc caaacttaca tcttcgtcca
    31861 acacaagcag cgcctgatac tcatttcgct gtacttctac ttttttttcc atcattcggc
    31921 caatcaattc aatatcttcc aaatattgat caaacgaggc ttttgacagt tggacatgct
    31981 ctctcaaacc attgatagag gctgttcccc cttgcagaac aaggtttcgc aaaatcagga
    32041 tctgtaactg ctcttttctt tctaataatg cttcaatctt cataggcagt attcgccacc
    32101 tttgaccaca ccatatctgg cacacggtat tctggctgga aaaatagctc atgttcttct
    32161 aactgttcaa acgtccatcc ttcttctact gcaattgtca gttggtcaag aaggtggaac
    32221 atctcttttt tgctttggag ctgtgctcca agaatctttt tttcagaatc aaatagaaat
    32281 ttgagtttaa ctttgctttg atttattgct gtaagcttgt agtctacgta tcctgtttca
    32341 attttttggg gataaaaaat gctctcttct tctgtcaaac ctacgcttcc taagaaatag
    32401 ccaaaccact gattgccgac tggacgatag gttccctgat cctttgtctg tgagccacta
    32461 attgtcttgc tgacatttcg tgctgtacgg acagcgttat ttactagaga aacatacatt
    32521 ttttcatttg ttggacgaaa agttacttgg atcgcatcgc caatcgcata aacgtctttt
    32581 tgagacgttt gcaagtagtc atctacccag atcgttccat catcattcaa tgttaattgt
    32641 tcttcccaca tctgattgtc gggacgagaa tgattagcca gcaaaacaag atcatagttc
    32701 tcctttcttt tttccgtctc tacaatagcg gtttcatttt cggtcaaaga cacaacttgt
    32761 tcttctaaaa aaagtgaaag cccttgattt ttcatttcct ttactaacgg ttctgtcatt
    32821 tcaggatcta gataacgaaa aagaattgac tttcggcttt cgtaaagatg gatttgtttt
    32881 tttcttgatg ccaacccttc agctatttcg attcctgctt gtcctgcacc aataattgca
    32941 attttctttg cattcatgat cttttgctga agagccgtta cgttttgtat ctttttaact
    33001 gggtgaataa gcgttgattc tgcagaaata tttcgaaact tttgatttga accagtcgct
    33061 agaatcaaac gatcaaaatc caattttttt cctcctgcta aaacgacttt tttttctttc
    33121 aatcctatta ctgtcttttc tgtgtaaaca tggattcgat agcggtcagt cagttcttct
    33181 ttcgtgatcc aagaaagttg tttttcactg gtaacctttc cttttaatat caaattgaac
    33241 ccgctgggaa tccatcctaa cttcgattgc ttttcaatca aatatatttc acttgttggc
    33301 atcaattggc gaagataaat agccgcatga atccctgcaa acgacccgcc gacaattaca
    33361 atgttcatct gcattcctct ttcttataag gtgttctact gctaacttct caatcagaaa
    33421 acacagtatt cataactcgc tttcaacctt atgatacata gcgatgcagc agaatcaacc
    33481 ctctccatca taccgtgttc taggtctgct tctcaataat gtactagtgg acctaattga
    33541 agagtatcat ttctgaagag atgtttcaaa aaatgtactc ttataaaaga aaaaaactcg
    33601 ccttttacgt acctctgtcc aaataggaaa cagaaaagaa cgaaaagacg agttttagcg
    33661 tgtgtaatgt aatagttaga atagacacat catttatttt taattcttta atgcttcaac
    33721 aactgcttcg cctaattgat gagcagattg aggattttgc cctgtaagaa gccgcccatc
    33781 aatttgaacc acttctgaaa aagctgctcc agactgatag tttgctcctt tttctttcaa
    33841 agcatcttct gctaagaatg gtacttcatt cgttgtacca tttgcttcct cttcttcatt
    33901 actgaaccca gtcactgtac gtccagctaa aatagatttt ccagactcat ctgtaactgg
    33961 caacaatcct acaacaccgt gacaaacagc tgagaccagc ccttcatttc gatagatttg
    34021 tgaagcgact ttcccaagat ctattgcttc tggaaaatcc cacattgttc cgtggccacc
    34081 agcataataa accgctgcat aatcatttgc atccacatca tcaggacgta aggtatttcc
    34141 caaggcccga tttctgaaat cttcatcttc ataataggcc caatcgattt catccatatt
    34201 caaaacactt tgcggttcta aaggtacata tccgccttta ggactgacaa aatctgcatc
    34261 gatcccattt tttactaata catcataaaa atgagtcagt tcacttaacc acaaacctgt
    34321 aggacgctcg atcttttcgt acttttctac atttgttaat acgatcaata ctttcatttt
    34381 cccatcctct ttctataaaa attgcgttat tgataacgtg ctttcaagaa attatataat
    34441 gggcttggca aataaagctc tttatatgct tcttcaaaag gtttcgttac aaattcatcc
    34501 tcacggtttt ccaataattt ctctgcccag tcaggatcga cgatcatttg ctgtccaatt
    34561 gctgcaagtt ctgcatattt caatacctgc tctacatctt cgcgattgcg gatcccaccg
    34621 acaccaacta aagggatctt tccttgaatc gtgttatgga ccacttcaag aatcgattta
    34681 tcgttgtatt tatcagaacg agctattcga tcatacatat ttaatgaaac atgcagataa
    34741 tctagttttg actcacgtaa tcgttcaaga agccagatcg tgtcttcaaa acggatacct
    34801 ggtgtttcat attcttctgg tgagaaacga taccctacga tgaatggttt tttagcatat
    34861 tgttcaaccg ctgagaaaac cgttgttaat aattcttcaa taaaacgata acgattttcc
    34921 aagctaccgc cccattgatc ctctcgtcta ttcgaatgcg gagagaaaaa ttgttggatc
    34981 aaatacgtat ttgctccatg caactcgatt ccatcaaatc ctgattcaat cgctctacgt
    35041 gtggctttgc caaatgcttg gattgtttca acgatttctt cttcactcat tgctcgtggt
    35101 gtttccgcat caggacgttt tgctgcaact gcacttgcag atacaggctg ttctccagat
    35161 aaagttgctc gacttgtcat tcgtccaccg tggaaaatct gaataatcgc ttttgcgcct
    35221 tctccttgga ttgctttcgc tagctcactt aatcgaggaa tcatttcatc atgagcgatg
    35281 ctgagttcac ctggccagcc ttttccgata tcttggacat ttgcagcacc agtaataaca
    35341 gcaccaagac ctttagaacg ttgtttataa taagtgatct catcttcggt gatcactcca
    35401 ttgaaaaagc tgagttgtgt cgtcataggc gacagcatca atcggttctt caattgaact
    35461 cctgaaggta aagtaattga ttgatcaaat tgtgacattg tcattcctcc cataattcgc
    35521 tctgattaac ctatcgagaa tcatctatca ttaaaccact cgattagttg tacatgcaac
    35581 taatttgctt aaaaaatttt attttttttg taacttatct gttgcatcat tcattgtctg
    35641 ggctaattct ttacttgctt catttcccaa aactgctttg tatgactgat gaagttcttc
    35701 ccagctacca tcgacttcct tagcaaattg gcgtccttgt tctgtaagat aaactaatga
    35761 caagcgacct tcgctaactg ttttgacgta tcctttatat tctaattttt caacaaaacg
    35821 agcaatcgtt gatggggcgg aatagagcat ttgtgcaata tctttttgtg gtattccatc
    35881 tttttctttt aatatcaata aaataaaacc ataagttggt gccagacctg tccttctaaa
    35941 cgcttcatca gctaatttat tcaacatgcg atctagcttt ttcacgctaa agaaaagaca
    36001 ttcatctaac gctttttcaa ttggcttttc catttcatcc cctccattgg cgtacatatc
    36061 atagtatgat ttttattttt tgtcaaaaaa cacggaataa tgtccgcctc ctctgtctag
    36121 atttgaaaaa aagaagtagc catcttcaaa gaatttcggc ttgttttcga caaaactcct
    36181 tctggaacac cgtgaatcag aggttgtgaa aaagtcgttt agttttgagt atgaagaaaa
    36241 attttgtgaa aatggctttc cacatttttg cataaatttg gcttaatacc gaaaaactgg
    36301 cttttgaaca ccgtttatat cagaggttgt gaaaaagccg tcctgcatca agtaataaga
    36361 acagccaaac aaaaatagtt cctcatattt tgtcgttttt tgagctaatg ccgatggtca
    36421 gctgattgta caccgtttat tgagaggtcg tgagcctgcc gttgaactcc gagtcacaag
    36481 gagcaatttc aaaaaacagc ttctcatgtt ttatgactat ggtgacttgt gatcgaggag
    36541 ttggcaggag aatactgttt attcgtaaag aaggggctgt gacaagactt ttgtcacagt
    36601 cccttatttc cttttattat aggatttcgc catttgattg gatgacttgt ctgtaccaat
    36661 caaatgattt tttctttaac cgtttctttg tgccattccc ttcgtcatct tgatcaacat
    36721 agatatatcc ataacgtttt gacatttgtg aagtagaagc gctgacgata tcaatgcagc
    36781 cccacgacgt ataaccaaat aaatctactc catctttgat agcttccttc atctgctcaa
    36841 tatgctgctt caaatagtca atgcggtaat cgtcttgaac ggttccatct tcttctactt
    36901 tgtctatagc tccgagtccg ttttcagcta tgaacagtgg tttttgatac ctatcatata
    36961 attgattcaa agcaattctc aaacccttag gatcaatctg ccagccccat tcacttgatg
    37021 gaagatacgg atttttaatt cctccagtta ttaagtttcc ttggacccct tcccaatttt
    37081 ctggatgagc actgactgca ctagacatgt agtagctaaa agaaacaaaa tcaacagggt
    37141 aggctgctaa gatttcttca tcacctactt ctatttttaa gttgacacct ttttcttcaa
    37201 acattcgttg cgtatacgct ggataatatc ctcttgcttg aacatcacta aagaacaaag
    37261 aagttctttg ctgctcaatt gttttttgaa tatcatccgg atcacaagaa tacggaacaa
    37321 gaagctgata gctgatcata caaccgactt gtgaaccttt gataatttca tgacaagctt
    37381 ttgtagctaa agcacttgct ataaactgat ggtgtgcacc ttggtatttc gcttgttcca
    37441 aatggggatg gttttcttca attactccta cgctaacaaa agggtgatgt tttacacagt
    37501 tgatctcatt gaaagtcatc caatatttta ctttattttt atagcgtttg aatactgttt
    37561 cagcgaaacg aacgtaaaac tgaataagct ttcgattagg ccatccacca tattctgtaa
    37621 ccaaatataa cggcatttca taatgggaaa gagaaacgac tggctcaatc ccatatttta
    37681 gacattcgtc aaacacttga tcataaaaaa ataatcccgc ttcattgggt gtttcttcat
    37741 caccatgagg aaaaattctt gtccatgcga tagacatccg atagcattta aaacccattt
    37801 cagcaaataa acggatgtct tctttaaagt gatgatagaa atcatttccg tgtcttttag
    37861 gataataata cttgctgttg ggatcctgcg ccgcttttac ttgctgatgc gtcatcatat
    37921 gccattgatc tgtccatttt tctttaggta aatcgctgtc gaatgtatac acatcagaca
    37981 cagataatcc tttttcatct acatcccatg caccttcaca ttgattggcc gctgtcgctc
    38041 cgccccataa aaatccttct ggaaattttt tcatatcgat ccccctaaac ttgctagttt
    38101 tcttgtttga ttatttttct tatgactagt aatgatattt ttgaatctac tactatttgt
    38161 aacaataacc attgtggtcg gatcatatcc ctctttgatt aattcttgca aatctacttc
    38221 catcaataaa tcgcctttac gtactttttt tccatcagat actgcacttt gaaagtattt
    38281 gccatttaaa ttcactgtat caataccgat atggatcagt atctctgctc cttcttcact
    38341 gactacccca attgcatgtt tcgttggaaa aactgttgaa acttccccgt ttacagaact
    38401 gtagattttt ccgtccgttg gaatgatcgc aaacccttct cctaaagatc cactagcaaa
    38461 tgttggatcg tttacttcag ataaatcaat tatttcacct gctgcaggag tacttaacac
    38521 tatatccttt gaggattctt cttcgatttc atccttgtag ccgaaaagaa aagttagcat
    38581 acaggaactg atcatcgcta agaaataact agcaactagc caaacaaatc cttcaccaat
    38641 ataaatcggg aaagacaaaa tacttcttgt agcaactgcc aaagcaccgg ctcctgcggc
    38701 accagctact ccaccaaata tagctccaca tatacaagca atgtaaaatg gtcgtttata
    38761 tttaagagtc acaccataaa cagcaggttc agtgattcca aataatgctg tgataaatgc
    38821 agataaagat aaacttttta ctttcttatt tttcgttttc aaaaataccc caagtactgc
    38881 tcctgcttgc gcagctacgg cagtcataca tgctggacct agcgtatcac gaccgtagaa
    38941 agaaagattg ttggtcatta ctggtacaag tccccaatgt aacccaaaaa tcactaacac
    39001 ttgccaaaat ccgccgataa cagcaccaga taaaacaggg ctaaagttat aaacagctaa
    39061 atatccagct gcaatcagct gacttgcata atctgcaatt ggacctacaa ctaataaaat
    39121 aattgggacc atcacgatga tacaaatgaa tggtgtcaat aaatttcgaa tactttcgtg
    39181 caagcttttg cgaatcttag gctcaatata agaaagaacc catacagcta aaattgctgg
    39241 aataaccgta cttgtatacc ttgctagaat cacgggcatc cctagaaatc gcaaggttat
    39301 gctatcacta tatgcactga caatcgtagg ataaacgaga gctgctgcaa taaccatagc
    39361 gatgaaacga tctgtattga acttttttgc agcagtatat gccaaaaata taggcaagaa
    39421 atagaaaaat gcatcagctg ctgcattcaa aatgatataa gttcctgatt cagtagttaa
    39481 taaattcaaa ctcgtacata aggcgagtac tcctttgatc aaaccacttc ctgccaagac
    39541 gcctaaagtc ggggcaaaaa cagcggcgat catgtctata aaagagttta aaatgccttt
    39601 tttctcagtt cctctctttc cactagatgc atcatcttct agtttcattt gtttggataa
    39661 tacgtcatac acttcattta ctgcatttcc tactacgact tgaaacattc ctccagcttc
    39721 gactacagtg atcacacctt ctagttgctc taccttctcc ttatctgcct tcttattatc
    39781 ttttagggta aagcgtaacc ttgttgcaca atggtaaaca ttgctgacat tttcttcgcc
    39841 tccgacaaat cggacaatat ctttcgctaa ttgtgaatag tccattttta cttccccctt
    39901 gttaattaat gccgtagcaa tccttcttac aagataagta tagttcttag aaaacggttt
    39961 ctccattcaa ttagtacccc ttctaatagc gaacgaaact gtacaatagt gtgtatggtt
    40021 tacttagccg agcaaatcac tcactgcttg aaagaaaaca agtatatcgt ttctcttata
    40081 gtcaaaggag acaaaaaaaa cacgcttgat cttcctttgc tgatgtataa gtggtatctc
    40141 aagctgatac tctgtgattt ttgtttctac ttggcttttg ataagacagc acaacaaagt
    40201 ctcggcattt aacggaagca taactaggtc agaactagga gagattagtt gctgaatgga
    40261 atctatcttt ttatggattt ttatttgatt ttcttctttg tagtaatgat caagcagttt
    40321 tgttttcttt ttttcttcaa ctatggtcag cttttcacgc aaaatctgat aaatctccca
    40381 agattcaaac tcatctagaa cactaggtag ataaatcaaa tcatcccact caaaaataag
    40441 ctcttgctca gtagtcaaaa ttgcatcata ttccgttatt ttgtttgatt gatttttgaa
    40501 aagatacact ggttctatcc ggcattcttt gatccacatg ttcatacttt gttgaatctg
    40561 tttttttagt gtattcaaaa tactaattgg ctggttacta acaatcagta tctccccttg
    40621 ttttcgaaaa ggattcaacg cttcggcaag atacaaaaca aaataagcgc tttcagctaa
    40681 attgggacgt aattgaaaat gtattgggaa gaaacgccga attaaataaa tttctaaagg
    40741 ataacgggag atgatctttt gtacaaaatg attcatggta ttatgtccgg catccatcct
    40801 cgttttcatt tgtttgatat gggttagcaa aaattctgtt tcatggaaca ataacgaaac
    40861 aggaagatct aaaaaacgaa taatcgtttg ctcaaatgct cttagattct tctctatttc
    40921 tttgtttttt tcatcattaa tcatcaaata atttaactct aatagtcgat tttcaattgc
    40981 ttgtttttct tgattggaaa aagaataggg tagttctgat gataactttt ttgtgagggt
    41041 ctctaccatc ggaataaata atgtatacct gtttgttttt tctaaaagtt cttctcttcg
    41101 aagaatggtc aaaacgagat accgagaaaa tcgtatgaag tcctctcctg aaacaatata
    41161 attatatgat ataagaacct cttttaatgt cttttggaca gtcggcatga tattggaaaa
    41221 aattgtactg atttgttgag gaaaccttgc gtgttggatc accgtttctg ttccaacaag
    41281 agataagaaa attctttttg aattttcttc agcaatgatt tttagtcctt ttgtcgacga
    41341 aacttccagt tctaatttag gattgcgctc gatccaacgc aaaatcgttt ttatttgtaa
    41401 tgatacggct gtttttgaaa gaaagaaaat gtctgctatc ttttgcatac tgacataccc
    41461 tttttgaaac aataagtacg tcacaatagt tgaagctcgg aaatccatgc tggaatagat
    41521 tttatgtttc gtcacctctt gtatgatttg ctgtttagtt tcagattcaa ttgattctaa
    41581 aaaataacct gaacgtttat ttgactggat aatgattttc ttctcgtaga tagcaagcat
    41641 atttttgatt tcagtttgga tcgttttctt gttggtacct aaagcttcag ctaattcttc
    41701 gcttgttatc caatgattct tatttcttaa tactacaaga atttggagtt gtcgtttatt
    41761 taagtccatt tgcttacacc tcctctttgt tataaacata caggaaaaac ctctcaaatg
    41821 acaatagtca cttgcagagg tttaaaaatc atttgaagaa agatctatat tcaaggtttt
    41881 taccattaga ctggataatt tgtttataat attcaaaact atcttttttc aatctcctaa
    41941 agcttccgct cccatcattt tgtctatcca cataaataaa gccatatcgc ttcctcattt
    42001 cccctgttcc tgccgatacg atatcgattg gtccccacca taagtaacca atgatttggc
    42061 aaccatcttt tattgcctca gcaatttcct gaagatgtat ttttagatac tcacaacgtt
    42121 ttggatcgtg gattcgattc aattcatctg gtgcttcatc tagtccaatg ccattttcaa
    42181 ctatgaataa tggtaattca taacggtctg tcaattcatt catgacataa cgaaacccta
    42241 gaggatcaat tggccaactc caaggttcgg gagatttttc cttcaaaaag ggattatcga
    42301 aaccatttgc tccgccagta tctacgcgca tttctgcttc ttttttatag acagcgctac
    42361 gataataact aaatgcaata taatctgccg tgttagcttg caagcactgt tcgtctccat
    42421 ctaacattac tggtgcacag tcttcttcct tccatgtcct gtaaatataa gctggataat
    42481 gccctcggca catgacatcg gagaaaaacc atgaattgcg tttaaattgc agtgaaccaa
    42541 atacattctc tggatcacag tcatatgcat aagtcgctaa tgcagaaaag ctacacataa
    42601 tacccatctt agcatttgga tcgattttct ttaataattg agtagcacgg gcgttcgcta
    42661 gaaacatatg atgacaggct tgataaatca ctttttttgt tagtgtagca atgggttcaa
    42721 gtttatctct agcagggaat gtaaccaatc cagcagctgc ataaggcata cgaaaagcat
    42781 tattgatctc attaaaggtc atccaatatt tcactttccc ttggtagcgt tcaaagacgg
    42841 tctgcgcata aaattcaaaa aagtcgatta attttcgatt ttgccacccc ccatactctc
    42901 ctaccaatgc taagggggtt tcataatgac taagagtaat tactggctcg atatcatatc
    42961 gatttaatgt attgattagt ctgtcataaa atacgagacc agcctcattt ggcttctgtt
    43021 cgtctcctct tggaaatatt cgtgcccatg agatgcttgt tcgaaaagct tttaaaccta
    43081 actccttcag taaacgaata tcctcttcaa atcgatgata aaaatcaatc gcttcatgag
    43141 aaagataatg gagtgattcg tctaaagcaa tctcccaaat ctttttttct tcattccact
    43201 gaatactagg atgctggttc atgatcccga taagcgtatc tgtcacatta ggtaatttgc
    43261 cgtcttccaa ccatgcacct tcacattgat tagcagctac tgctccgccc cataaaaaat
    43321 tttctggaaa tatttcctga tccataacta tctctcctcg ctatcaacaa tttcttactt
    43381 gaagtatagc tcgattcatc aaaacaagat attctaacta tttcggcaga agagaagaaa
    43441 aaaattgaat gctactcttc atttttaata tttatatata acaaatacat aagacgatcc
    43501 ccgaaagaaa acactcgtta accatctaag caaacgattt attttacttc caacacaaat
    43561 gcttcataag gtcgtaaatc aactttgccg tctggtaact gtttcagagg ataatttgac
    43621 acaataaccc ttaaagcttc acgtggaata gtgaacgtct gcttttcact ggacatatta
    43681 caaataacga gccattgctg gtcttcatat atgcgagaat aggcaaagac atgctcaggc
    43741 gtcttttcca ctaattcata gtctccccag acgatgatgt catgttttct acgcaaatcg
    43801 atcaatttct tgtacatata aaaaacagaa tcttgatctg ctaacgcttc ttctgcattg
    43861 atttctttat aatttggatt gactcgaagc catggaattc cagtagtaaa cccagcatgt
    43921 tcacgggcgt tccattgcat aggcgtccta gcattgtctc ttcctttcgc cttgattgat
    43981 tccaagattt cctcttttgt aaatccagaa gaaatccttt cgttatacat attgattgtc
    44041 tcaatatctt ttgcttccgc gatatcatcg attgggcaat tcgtcatgcc taactcttct
    44101 ccttgataga tataaggggt gcctttcatc atatggagca agatagcaaa catcttggca
    44161 ctttcttttc gatacacatc gtcatttccc caacgagaaa caattcgcgg aagatcgtga
    44221 ttattccaaa ataaactatt ccatccttca tcacctaaag atgtttgcca tttggataat
    44281 acttttttca gttcagagat actcaagggt ttcaaatccc atttgtcttt gccttcttgc
    44341 tgatctaatc ctatgtgttc gaattggaag accatggata attcatttct tttaggattg
    44401 gaataaagtt tagcgatttc ggtagttgct ccccatgttt cgccaacagt catcagattt
    44461 ttgtcaccaa aagttgcttg attcatttcc tgaagatact catgcagttt aggtccatta
    44521 cttgtgattt ctttatccgg ttctttgcca atcatatcga tcacgtccat acgaaagccc
    44581 ccaatacctt tatcgatcca gaaattcatc atttgataaa tctcttggcg aacctgttta
    44641 tttttccaat tcaaatcagg ttgacgcttg ctatacaagt gcagaaaata ttgccccgtt
    44701 ttttcatcca actgccaagc agaaccactg aatattgagc gcaatctatt aggctctttt
    44761 ccattgaccg gatcacgcca aatataatag tcccgataag gattttcttt atttttacgg
    44821 gcctcaatga accacggatg ttcatcagaa gtatgattca ccaccagatc catgatgata
    44881 cggatatttc ttttctttgc ttcttcaatc agttcttcca tttcttccat cgtaccgaat
    44941 tctgccatga ttgcttgata attactgata tcatacccat tgtcatcatt cggagactcg
    45001 tatactggag aaagccaaat tgcatcaata cctaaatacg ccagataatc caacctggaa
    45061 ataatccccc gcaaatctcc aataccatct tgatttgaat cttgaaaact tcttggatag
    45121 atttgataaa caactgaatg gtgccaccat ttttgttcca tgattttcct cctataaatg
    45181 gatgtttcta ttttttgctt aatcatttat tttagtctct ctcactaaaa attgtaacgc
    45241 tttcaaatag ctattgcacc ttgttatcgg taacagaata aaacaaaaaa acagctgagg
    45301 aaattccctc aactgttttt tgaaaggatt gatttatgca gggaagaatg ctgatttcac
    45361 aacttcttta taaacggtgt tcactcagct gtcccttggt attagctcaa aaaacggcaa
    45421 aatataagaa actatttttt cgtttttttc tctaatactc aggccagaac gctgatttca
    45481 caacctcttt atttcacatt caatatccac atgaatccca caaatacaaa gaacagacca
    45541 tacatgattg gagatacttc ttttcctctt ttagctgcta acatggtaat tggatagaag
    45601 ataaaaccta atgcaatccc atctgaaata ctataagtca aaggcatgcc gatcaagatc
    45661 aagaatgaag ggatcgcaat ctctaagttt ccccattcga tttgtcgcaa agattgtgcc
    45721 atcaatactc ctaccataat caatgctggt gcagttactt gtgaagtaac aactgatagt
    45781 aatggagaaa agaacaagcc taacaagaag aaaatccctg tagtaatagc tgtgatacct
    45841 gaacgtcctc caacggcgat accagctgat gattctacaa atgcaccaac aggagaagta
    45901 ccaaataagg aacccgcaag catagctgtt gaatcagaag ctaaagcttt ccctacacga
    45961 ggcatcttgt tgtctttcat gaaacctgct tggtttgcta atccaactaa agttcctgct
    46021 gtatcaaaga aagtcacaag caagaatgtc agcactacga cccacatttg aagagaattg
    46081 atgtccccta catgttttaa tgcaactaaa aatgttggtt tcaaacttgg tgctgcggca
    46141 acaatttcag aaggcattgg aatcaaacct gtgaccagac ctaaaatcgt tgtagctgcc
    46201 atcccgatga agatgccacc tggtacacgc cgaacaagca agatagcagt tacgactaat
    46261 ccaaaaatcg tcaaccaagt agaaccaacg ttgagtgatc ctaatcctac taatgtagat
    46321 tcattcgaaa cgatgatccc accttcgctc agaccaagga aagcgataaa tagaccgata
    46381 ccgccagaaa tcgcatattt caaatctgct gggatcgcat caatgatcat ttcccgcagc
    46441 ttgaagattg tgatcaaaat aaaaatcaaa gaagcaacga atacgccggc taatgctgtt
    46501 tcccatggaa tccccattcc taaacaaaca gaataagcaa aaaaagcatt gatcccaaga
    46561 gcaggtgccg ttccaattgg ataacgggct aataccccca ttaaaacaca gccgatcgca
    46621 ctggctaatg cagtcgcagt aaacactgct ccttcatcca ttccagaagc acctaataca
    46681 gttggattta caaataagat ataagccatt gagataaatg ttgtaaatcc tgccagtacc
    46741 tcacgtttta ccgtggtgtt caatttttct atttcgaagt aggaaagtat tttttccttc
    46801 atcttccatc cccctaaatc cgaacattat aaataaagtc cgttaaaatt tcgatttatt
    46861 aataaaacaa cgtgttttat catatactaa aacaaaacat aagtaaacaa aaaattcgga
    46921 ttttaagcaa aatccgaacg ttccatctga ttaaatccct ttatctcaaa gttcatgaac
    46981 attcactttg gattacaaga atttctttat tgtgttaata aagtttcttc attctagtct
    47041 caaaaatcaa tagtgtgatt tgattttacc atttcgtttc tgttcttctt tgatgaattc
    47101 ttttgtatcg acaggattca gattatttag tccgccaaaa cctgtatcga ccatttttcc
    47161 ccagcctttt gtcttctttt ttcctgattt gagattcttt gctcgaagct tctcactatg
    47221 ttttgctcgc cgatacttca aataaccttc taatcttccc attagatcca ctgtttttcc
    47281 tcctttttat tcaatcagac gactcagctt ttcctataac aaaataattg ccttcagggt
    47341 cagaaaaatt gaaagtcaag atgccattgt tatctgtgat ttctcctggt tcttccatgt
    47401 tctcgtagat agtttcaaat tcatccgtaa aaaatactaa agaaggcggt ggtcctaata
    47461 cctctggtga aaacttctgc acaaatactt ttgggaatac gcctaattct aattcttttg
    47521 agatgctgag tacaatactc ttaaattctt ctggcaattc gattgtttca gaaatttctg
    47581 caccaatttt ttctacaaag aatcggcaaa tcatctctac gtcattgaca taaagcatca
    47641 cacgtgtttt ttgtatcatc atttgaccct tctttctatt tgattttctt tcctgtctat
    47701 aaactgattc cattatatca cgaaagcgca aacaccttgt gtttgatact attcaagaaa
    47761 aataaagcaa tagtttctag gattgctttc ctccacaaac tttttttaca aaaaaaaaac
    47821 ggcaatgaat gccgctcttc ttatttcgat tcttttataa ttctgcttct gattcatctt
    47881 tggttagtgt gtgtctaaca ctagttacgc caaatgtttg atcgattttt tccttcaacg
    47941 cttcgattgc ctgtgcgcca cgtgccgctt gttcagcatt gatggattca atgaccagca
    48001 ccgctgcttg tgtttcttcc gtcagcatcg ttctttgggc ttcacgccag ttgagacagc
    48061 gacagatcgc tccttgttca tcatagtaga tgatttcttc cggaagtgcc ggagcatcgg
    48121 aatctgcacc taaaggcagg aatgattcgc caccttgggc ttttcctaaa tgcagatttc
    48181 ctgcgatctt ttcgatatct tctccgccgc aaggtacgcc aaaagacaag gaaatactat
    48241 tatagatatc tacaagcgga ttgattggga aaaattcccg ttcttgattt gcacgtttca
    48301 gtaaagcttc aatagaagaa cgtgcacctt ttttagtctt gaatgtggta aatgcctgac
    48361 gccactgagc aatgacttcg ttttggctga atgtttcttc tgtaaggtaa tttcttgctt
    48421 cttttgctgc ctcattcaat aattgatgat acgtttcttc actttctttt gttacgtggt
    48481 tatcgatacc atttacggat aagatttcga tggttgcttc aggaaatact tcccagaaat
    48541 tggtatccac tattactttt ttcatctgtt cacacctctt gattagaata attgcttgat
    48601 gaatagatag tctgtttggg gatcatctcc catataaaaa acatgttcgc tgtatttgat
    48661 aaatcctttt ttacgataaa aagcgagcgc aacatcgttg tgttcccaaa caccgagcca
    48721 aatggctgtt ttttgctttt cttttgcttt ttcaatagct gtatctagta aaaatgtacc
    48781 gataccttga tgtttaaatt tttttcgtac atagattcgc tcgatttcta aaaaatgatc
    48841 agccatttcc tcagattgac tcgttcctgt atttagtttc aggtaacccg caggctcttg
    48901 atcgatactc actaggaaaa aatcggtttc tttatctttt agctcttctg taagtttttc
    48961 tagtgcataa gcttgtgtca agtaatcagc taaatgctcc ggtgaattat cttttccaaa
    49021 tgtatctgta aatgtttcga tactaatttg ttgtagtaag tctacatctg aaggcgtcat
    49081 ttttcgaatt tcgtatttat tcacggcttc ttcctttcaa tagatccttt tattgccttt
    49141 tttgacaaaa ttccaatctt cgctaacatt cttgcatact ttatttaaaa gatattccaa
    49201 ttgttttgct tcttcgtcag aaagaccatt taatgcgact gcattggagt agttgttttc
    49261 tcgaatgatg aaaggataga tttctgctcc ttttttagtc ggatagagtt tcttgatttt
    49321 tttattttct ttatcttcca aacgttcgat catcccattg gattctaatt tcttgattgc
    49381 tcgggcagtc gttgtacgat ctactttgat catttctgct agtttttctt ggatgattcc
    49441 aggattttcg caaatacgta ctaaataaag atactgtcct cttgttaaat cgacttcttt
    49501 gaattcgata ttgctaatag aatctagcgc tcgggcaatc attccgatgt ctcgaaggat
    49561 ttcagccatt tcatcccacc tttattttgt ttgtaagact agttcacctc tttttgttgc
    49621 aaatgcaact attttcaata aaaaaatcaa gttctttttt aataactagt aaagtatatt
    49681 cttttcttct tttacgaaaa agctcaatca caatagatct ggtttttgtt ttctaaaata
    49741 agtaactgtt tcttcgttgt tcgcttttct gatagctttg gcaactcttc tatactaaaa
    49801 aatcccatgt tggaagtttc attattctca ataaacttgg cctcttcacc gtggatcgca
    49861 caagcaaaaa caagtttata atactgaaaa agctgtggaa tatctttttg tttattcgta
    49921 tcaaaaactg ctcgcaactg agtagtttct actgttaatc ctgtttcttc atagacttct
    49981 ttacgcacat tttcttcagg agacaatcct atttcagcaa atccaccagg aagtgaccat
    50041 tctttcgtcc gtttatcttc gattagtagg accttgccat cttttttgat ataggcacga
    50101 acatctactt ttggtgttgg atgtccttct ccaatcgttg tgagcgcttt tatttcttcg
    50161 aaagtttctt ttcctatttc actgatcagt tccaatgaaa tcgtccggat ctcctcaaaa
    50221 cgctctttat caaatacatc ttttccataa tatagaccag cttgagaaag tgcgagtagt
    50281 cttttgtatt gagccaactt cttgttcatt ctcttccctt cttttttagc aaatgtatga
    50341 ctatgtaatc aagtatagaa gactggttta attacggcaa ataaatataa tgaaatctgc
    50401 aataaataaa agaatgttaa aaaactcgag aacaaaagac attcgacttc tctggggctg
    50461 tgaataaatg gcgttcaaaa gcttgcatct gcggtaataa gccccaccaa acgaaaaata
    50521 tgacgagcta ttcttgtctg gctgttctta ttaattgagg caggacagct ttttcacaac
    50581 ctccccacta aacggtgttc tcctaccaac tcctcggtca caagtcacaa tattcatcaa
    50641 acatgagaag ctgttttttt gaaattgctc cttgtgactc ggagctgaac gacaggctca
    50701 cgacctctcg gtaaacagcg ttcaaaagcc aatttttcga tattaagcca tttctttgtt
    50761 acttattgtc attgatttct ttttctaatt tatccaatag tggagtgtaa tccacttgag
    50821 tatagtctgt tacatcaaat tcatatagtg ttcctaactg gaatttgtca tattttcggt
    50881 cggcgatgat ctttttgaat gcttctttcg taatatgatt ggtccctttc gttcgatctt
    50941 ccaatacgtc accatagtga taatgatcca tgatatagct caaatgacga tctgattcac
    51001 gatcacgttt gtaccgacgt tgccataaca cttcaaagtc tgctgttagg cgaatcgtga
    51061 tcacctgata tccgtatcta tctgctaatt cttggagtcg tgctttttgc ttatcactaa
    51121 aaggatactc ggacacaatc actttctttc ctgcttccat atacaaatca agtgctttgt
    51181 aatagaaagg ataaactttc gtcctttctt gttccgcccg ttcttccaaa ttgttaaacc
    51241 cgatggattc tgcatagtat tccttgattt catcgagcgt gatggcatac atatctggaa
    51301 atcgttcccg tagtttattc ataagatatg tttttcctgt accaggacta ccagccagaa
    51361 gaatgaaata ctttttcatc tcatttattt cctaagttaa ttggactttc caagttcata
    51421 aacagtccaa tcttatgctt gacaatttct tttactgctt catttgctgg aatcacatta
    51481 tggcgaagag acttgttgat ttctgtttca ctaaaggttt ctttagctac tttcgtccag
    51541 ttgactaaaa gctccgttcc aacattgaat ttgcggatcc cgttattgat caattcagga
    51601 taatcttctt ctttcacacc tgttcctcca tggataacta gggggacatc aactactgca
    51661 tcgatttctt tcagcaaggg aatgtttact tctgtttttg atttgaattg tccatgattc
    51721 gtaccgatag caatagctaa tgcatccacg cctgtagctt ctacaaattt cactgcgtct
    51781 tccggtcttg tatatacctt gtcattttca gcgacatgga ttccttcttc tgtaccgccg
    51841 attgttccaa gttctccttc tacggaaaca ccgtgcgcat gggcatattc tactactgct
    51901 tttgtcttca ggatattttc tttgaaaggc agatgggacc catcatacat gacagaagta
    51961 tatccgctgt cgattgcttc tttgatatca tcaaagtctc gggcgtggtc taagtgcaag
    52021 actgcatcaa ccatttcttc ttctgcaata gctgtcatta cattgactaa cacatgcatg
    52081 ccgatatatt tagcggtatc gacacttgtt tgaataatga tcggcgaacc catttctttt
    52141 gctgcgccta gcatagcagg aagcatttct aggttatgcg tattaaaagc tccaactgta
    52201 aaattcaact cttctgctgt ttttgttact tctttcaatg ttgtatacat cttttattgc
    52261 caccttatct ttttatttgt ttcctttgat cgttacttgt tttgcaattt gtcgcatctc
    52321 atccattttg cccatgtagt aatcgatccc ttgatcatca ccagcacgag cagcatctgc
    52381 acgcttctgg ttatagaggc tcatcagttt tttataccca tctccgatcg tctgtttatt
    52441 ttccaaactc ttttctaaat attggatggc ttgatcgttc acatacaatt cagaaaattt
    52501 aagtccaact tgttcataaa gtttcgctaa tttatgctta tcttgggtag tggaaatctc
    52561 ttgtttcaat tgtgtaatct ctgattgaat cttttcggtc gcttctggcg atagggcttt
    52621 ttcttctttt gccagaactt ttttcggttc tttttctttt ttcttaaaaa atccaaacat
    52681 cattttccct actttcaatt aaaatgcttt caaaactggg cttaagatcc aggcatataa
    52741 gagtgctgcg gctactgtat ctacatcggt tgctgtagca ttgttgaatc ccatcgaatt
    52801 aaagatcgtt actagcaaag cgggcaataa tgtaataaag aaaccatgag caataccgcc
    52861 aatgatcgct cctcggcgtc cgccaactgc gttgccaaat atccctgctg tccctccggc
    52921 aaagaaattg gttagcatac caggtaaaat catcgctaag ccgaacatgg gcaaagtaaa
    52981 catggcaata atcgtaccaa tcgttgtcgt aatgaaacct aaaatgacag catttgggct
    53041 ataaggaaag aaaactggac aatctaaggc agggatcgca tcaggaacta atttcatagc
    53101 tatccctcga aatgccggca cgatttcacc taacagtaga cgtacaccag ctagcaatac
    53161 atacacaccc actacgaatt ggatggcttg taaaaaggca aacatgatat agttttgatc
    53221 tcctgataat tcagaagcga atggttcgcc tgcaaataaa acagtgatga tatatagcgg
    53281 gaccatcacg accatgacag acaaataagt atcttgcaga aattcgaaat gtgtcggcaa
    53341 cttgatatct tcgatcgact ttttattttc gcctttctca ccaaaaagct tagcaacacc
    53401 ggcttcaaat aagtacccga tcgtacaaaa atgacctaaa gcaatatcat ttgatccagt
    53461 gattttacga atgatcggtt gcgctactgc cggcatagca atggcgaaac aagctccgat
    53521 aaaaccaccg accaagatca atacgatccc tcgcagaccg gcaaaatagc caaagactgt
    53581 cgtcatcgtt gccatccata aaattgcttg accagttaaa aaaatgtact tccattttgt
    53641 gaaacgagcc aaaataatat tgaatacaaa aatggctaag aacgtcagtg caatatctct
    53701 acctaaaccc aaatcattca ttgcttgacc attgatagat tcaatagaag ggatgatccc
    53761 ttgcatatga aatccttcag taaagatttt cccgaaataa gttaaacttc caacgatgat
    53821 gctcgaaccg gcactcaaca cttgaaatcc taggagtgtc tttaacgtgc cagagatgac
    53881 ttgtcctgct gatttcttct gcagtagtag acccaacata gcaatcaatg caatggtgat
    53941 cgatgcctga gtcaaaatat tttcgatgat aaaattgata acgcccatgt ttttaccctc
    54001 ttttcttttt gtatttagat aactccctta tcttgcagaa ctggggtgat tttttcttca
    54061 atttcatttt ttgaaacaat atttttcaaa tagatcatcg ccgttttagg atcaactgcg
    54121 aacttttcga actgcgaacg aaaattttct gctgtgatga tcacatctgg tttcatggaa
    54181 actgcggaag aaatatcaca atggtccagt ttggcttcta ctcctaattt gttcaaaaca
    54241 tcctcagcag acatctgtgc tgcaaaacta cttcctaaac ctgcaccgca tacgaataaa
    54301 atgttcaatt tgttcatctt tgttctcccc cgtatcattt attatttctc aactactgaa
    54361 aaaagcagtt gtttgaaatc ttcgatattt gtgcattcaa tcaatcgatc caacttctct
    54421 tcgttgttga tcaattcaat tagttctttc atgatgttca gatgcgagta ggagtctact
    54481 gctgccaaac aaaaaataat ctttactgga tccatttcag gattaccgaa atcgattggt
    54541 tgctcaatcg tagctacgct gactcctaat ttattgaccc catcttctgg tcgggcatgg
    54601 gctagtgcca tgtgtttgcc aatcacgata tacggtccgt aatcattcac tgcacgaatc
    54661 atcgcttcga catagcgctc ttcgacaatg ttttctttaa ccaatggtct agcagctagt
    54721 tcaatcgatt cctcccaagt agtggctttt tctttgatca tgatattgct gtccgtcaaa
    54781 atatctttta acataggctg gatctccctt ttgttgattt ctaaattgtt tgtttcgaat
    54841 aatttttcta acttgccata gatgattcga tctactcggc caccactttc tttcatgaca
    54901 tctattattt gagtgaataa ctccgtcgat tcatgactgt taggctctaa ccgctgtagt
    54961 tcttcatttc ttttcaaaaa gtcttctata accaagatat tcgtctcagt taaaatcgga
    55021 tcgacaacta aaagcggctt atttcgataa ttcaattgaa aggtgctgaa aaccagattg
    55081 acatccaatt tatctactaa ttcgatttct tttgaactta aaactgcagt aatctcgatc
    55141 tgaggaaact tttctttcag attctctgct aacagatttc cagtagccat cccatggtta
    55201 cagacaacga ctgatttata aacataattc aagtctcgct tgattacact ggcgatcgtc
    55261 gaaaagtgga tgacaagaaa agctatctcg tcctccagta tcttgccacc aattacttct
    55321 tcgatcgtag gaacaaaatg agtgactgcg cggtagattg ggaaataatt tgttcggatg
    55381 ttttctttca atggattcat gacttggata tgattcttga ttcttacaat cagtgcagcc
    55441 atgtgcttat agagattttc gaataaagct tcttccttta gatggaaagg tacgtgtgtc
    55501 tcgttctcta caaattggat caattggatc gttagtaatt gagcttgtac ccactcgatt
    55561 gaattggaga tatctctagc attgaacgtc tcaatagtga aacgaagata atttctttct
    55621 acttgcggga cattgtccaa ttgaaattcc tcgatcatgt ggtcaataaa tgcagaaaag
    55681 ctactgtctt ttatttctgt atttttccaa ttaatggcag agataaattc atgtttcctg
    55741 attcgctgga tccagatcaa tgtaaaaagc aggatttgtt ttttataaat atcatcttct
    55801 tgtttcaaca acttattgga atagatctcc tgtatttttt tgatttccac caaaggaaaa
    55861 taatggagaa agattttttg agccggtgtt aattgtgcat cttgattcat aaagaagtcg
    55921 gtcattccca gattctgatt gataaaatca tagatcatcg tacggataga tcgttctgaa
    55981 cctttataaa ccagtccttg ctttccataa ctgacgatct ctatcccata actgaccagt
    56041 gttgctcgta accgtctcat atcttcatct aatgtacttt tagagatttg aaattcttct
    56101 tcttttttgt ttagatggat cgggattcgg ctgtaagcaa cggctaaaac tagatcaaaa
    56161 atacgttcgc gccgattcaa aaagccgtct ttcacatctt ttatttcagt ttctaatcga
    56221 gcttgctttt ccttttccag cttcaacaaa aaacctttgt tgcgaattgt acggatctcc
    56281 ggaagctttt tactgctcaa ccagatattc gcttcaagaa cttcctgacg gatcgtccgc
    56341 tgactgacat tgaactcact tgctagatgt tttgctttta ctggatattg ggctgtcatg
    56401 attctgtgaa gtatttcaat tgttcttgtt ttcatagaaa tgatctcctt ctgatttcaa
    56461 gtatatggtt ccgcttacat aataaaaagt agatatttct gccacttgaa gtggaaagaa
    56521 agtaagcaaa gcaaacaaaa aataagccat atgctttttc atctcctcaa cgaaaaagac
    56581 atacgcctat tattacaaaa attttgccca tctatacaaa aaagaggttg tgaaaaagct
    56641 gtcctgcatc aagtaataag aacaactaaa ctaaaatagt gcttcctatt tttcgtttgg
    56701 ttgttcttat tatcgcagat gcaagctttt aaacaccatt tagtggagag gttgtgacag
    56761 agatgttcag ccttgagcga taagaagcga ttttgaaaaa tcgcttccca tattttacaa
    56821 aatcgtgcct tattgccgat aggctatctc tggcacaccg tttattcaga aaaaggagct
    56881 gcgacaaggc ttttgtcaca actccgttca taaatatttc ctgtcaatcc agcataatcg
    56941 gctgaataaa atcggcttgc catctttttt ctttctcaga aaaatcaaaa taccatatct
    57001 gagaaaaata ctgtcgttgt gtcttacttc ctgagatcaa tcgcccatct tttcgatcga
    57061 ctgaataatc acagcatctg aaatcaattc ggatggcaaa actattttcg tggatctgtc
    57121 gataatttcc tacttcctga atagttattt ttttagtatg atttcttaca ccgtctgctt
    57181 tgtttttttg cagaactttc tgatgttcgg caaacagctt gtctgtataa cagcttctgg
    57241 ctttttcagg agtttcttct tcccaagcgg attggatctt catgaatatc ttttggattt
    57301 ccagaaactg tgctttcttt tctttagccg ttcctgacat gcgggacaat atctccgctt
    57361 tcagcctttt cttttgtctt ttattcttga cgatagaaaa agcagaaacc cctcctactg
    57421 acaaaacagc taatgcaaga aatcccgttt gctcataact agaaggacct gtacctggac
    57481 cataataccc ataagaatct ctgccgtaag aacgactgcc aaaataactg cccccatatg
    57541 aacgaccacc aaatgaacct ctgcccgaac ttcgaccgct agatgtacct ccaccatgac
    57601 cacccgcgac agcgaatcct tgggtcggca gagcaaacaa acataggccc actaacaaaa
    57661 tgattgctaa ataattgatt tttttcattg tcttcctcgt tatcttttat tacaaaaaac
    57721 tatttttatg atagccttgc taaaaggaag agtcaataac cagatgcata aactgttttt
    57781 ttagcaattt tgtcttattt agtcattgag taacatcgga caaatgtatg tgtcggcagt
    57841 ccataattcc tctatcttca gcatgaacaa gcttgcagac aagagatctg cgcttcctcc
    57901 aggagagatt tggttttcct gacaaaagtg caacagtgct gtaaatggac gatttggtaa
    57961 agcactttga ctagcagcat gagcaagttt ttgcatttcc actaacgttt tctgatcact
    58021 gcgatgcaat acgcatgtgt catctagcga actcatcaaa actaacaaca tatgcatttg
    58081 tttctgtaca tatgaatcat tatctagctc cttagctgct tgaattgcaa gcctgatatg
    58141 cggataccct aatatcgctt cttcatatgc accatttacg ccatattttt gcttcaccct
    58201 atgaccatga gtggtttttt tatgacgata ttttgtatca ggaaaagcag caagcttgct
    58261 gacatcatca agtattttcg ataaagaaaa aggctgttcc atactgattt tttgtgcaat
    58321 gacactgatc aatagcccca ttgcccaaat cgctccttta tgggtattga tgccatttgt
    58381 agcaatcagc attgcctttt ccgcttttcg cccaatctca gcaattcttt ctcttaactc
    58441 ctgatcaata gcatgatgcc atgctatttg agccatttct tcaaaaaaag gagttagcgt
    58501 cttagcagac ttaagaaata aagcatagtc catatcggaa tgtgcacccg catccagtgc
    58561 atccactaat ccaggttttg gacttaatgt tacttctgcg atcaatgctt cctctaccaa
    58621 cgcagcgagt tgctgagtca ctgctttttt tcgttcgtca tttatcatga cactcactcc
    58681 ttcttcctac tattacttgc tgaaaccttt tttgatagct acccaaatga tatgaagtaa
    58741 ccagcttaaa gcaaatgcac aacttgccgt cattagataa gctacaagaa tcatgactcc
    58801 tgaaggtaac tgcagccaac tatctttaaa caataataac agtacttgga aaacaaatac
    58861 attggctaaa tacgtacgat aagcataaac agacaaccat ttgaacaatg gcaattttgg
    58921 cgaatcgttt acaatcattt tggaagcgcc tatgaagaca gcaaagatga tgactaaact
    58981 gtataaactt tggatcgtat tcaagtaagg tgcattcgca aagctcaagt ctcctggatg
    59041 tgcgagcaat gaacggacag aaaagaacgc gataactaag gcaacaggta agaaaagata
    59101 acgtactctg tccaaatatt gatagacttt ttcgtgataa acaaatgcgg ctaccccata
    59161 aatcatgaaa ctagcaacaa accgatctaa taagtaccag ctgtcatgat aaggcccagt
    59221 caatacttgt gtttgataga acagatacca tgcgacatat aaaatcgttg aaccaatcaa
    59281 tactggccat acatattttt tattagcaaa tactttgtaa ccgagccaaa caaaaaacgg
    59341 catgaacaat tggatctgca gcatcataac ggtataccat aaatgaggcg ctccatcacc
    59401 tgtgacatat ttcagtaaaa agcttgcagt atccgtatac ggagtttgtt gttggactgc
    59461 tggaaatagc caaagataag ccgtcgtcca tagaagatac ggaacgacta gttcaaaaaa
    59521 cttttctttc aaaaattccc aataagacaa atgctgactt gtttttacca tattataaac
    59581 aattgcaaaa ataaacattg gtgctgtgta tttaacgatg acgtaaaagg taccaagaaa
    59641 agctgtattt gttgcgctgt ggctgtttgc caaagcaaag ctcaatatcg tttgcatcat
    59701 aacagccgtt acagctgata ctttctggaa gtcacttacg ttgattttga tttttttgtt
    59761 ttcaaacatc tctttctctc tctttttctt tattaccaaa gttctttggt taatttaggt
    59821 ccttcgactg ttttcaatag aatttttttc tctggctctc tcaaatactc ttttagtgaa
    59881 aaaccgcctt gccgagtcac tacttgggta tcgaattgct caaaaaaagc aggatgcgat
    59941 tgaattacct gaattggcaa ttcaatcggt gaatttgcgt acagcagcaa atcaaaatca
    60001 ctggtttctt ttactgccgg aatcccagtc gataattcaa atcctaagct gccgccgatt
    60061 ccccatttac atcctgataa tatgtttcta gcagcatgaa attgctgata aacaggataa
    60121 tccatgattt tctcttgtct atacgattct tgttcgatga tgtcccacgg atgaatgact
    60181 tgtttgacgg catgttttga gatttctgtt gaccatctct gattgcgggc aggtccacgt
    60241 aaaccaatcg gtagtatttc tgcgtgatcc gtcgacgcac gacgaactgt tccgaacatc
    60301 ttttcagtta gaacgaccca ttcaggcaag gtgaaccctt ctatttcatg tttatcaaaa
    60361 aggacaatat catgtgcttg aatcattttt tatgcatccc attcttcgtc cattttggca
    60421 cggactttat ttgtttcgac acgtccgaat gttttggctg tttcgtttgt gtatcgattt
    60481 gtcagcatcg tgtcatttgt attgcggaca tcttgaatgg cttcattgat tgcttcgatg
    60541 actttgctga cattttgttc tgaagcagct tggtcggtga tatcttctag gaaatgatag
    60601 atcgctccta gttttgtata attattgata tcgtaagcga tagctggaac tttttcagca
    60661 gctgcttcga tttcagcaac cgaacgtttt gtcacacgtg cagcactttc tttagacatc
    60721 gcttggacgg taatttcttt attgtttaaa gcaatcaagc ggcttgattg taatccatgt
    60781 gctaaaaatg cacctgaaat agcatttcct gcaatcaatc caataactgg atgtccagct
    60841 tgacggagtt ttgcataagc agcagcacta ttagccaaag ccacatggat accgatcaat
    60901 tcttcgttat agccgtatgc ttggcttggt acatcgatca caacgatgat tggccgtttc
    60961 acttttttgt ctttatcttc ttcgtaaacg tgatccaaaa tttgtcccat gcggaaacct
    61021 tcaactaaac caacttcacc gtttcgtaca cggtacatcg ggtttttagg atcaggtacg
    61081 attgatgtca cgatggcttc ttctatgaat ttacttgatt taccataata cacagtacta
    61141 atagaagaag ttggattttt catgccagtt agtgccgcaa accaatcgta accaacactt
    61201 gctgcagctg gttcatttcc ttctgctact tctggtaagt caattgattt tgcttgatgg
    61261 ttagcaattg cttcattgta atcgtcaatg gccattggtt ttgaaagatc taaagaatca
    61321 agtaatgata aataaaatgc tgagctttca ctgcgatgcg tgtcttttcg ttcgtccatt
    61381 gctgcgatga cagcagcttt gattgcttct acactatcag tcactaattc atcaatgatt
    61441 tttgattcta cccgttgacg agatcctaat gtattccaaa tcaagtcttt gtcactagaa
    61501 tcaaattctc gaacgcctgc ttcttgttca ataacttctg gtccattcaa accgactctc
    61561 gctttttttg ttgcgattaa ataactcatt aatgctgaag taatcgacat accgccaaat
    61621 gatcctacac gtcctggaat caaaccgatg actggtacat attgttttag agcaatgatt
    61681 acatttccga tttctgaaat agataacagt ccgtagtttg cttcttgcaa acgaacacca
    61741 cctgtatcta gtacaatgac tggaaagatc tcatttcctt ttttattttc ttctaacaca
    61801 tgttcaagtg cagcaacgat ttttgcaccg gaaacttcac cgataccgcc accttggaat
    61861 tttccttcca tagcgattac tactgcttgt ttgccattga tcgtgccacg gctgacaacg
    61921 atcccgtcat cactttcagg gacgattcct tgtgctggta aacttggcgc gatgatttga
    61981 tcgaatggat caatcaattc acgtccattg tcaagtagag cgttcactcg ttctctggcg
    62041 tttaattcta caaaactatt tttcatctga aagttcctcc attgcttgcg tcaatcgtag
    62101 gtacacaact cctggtgtag caccgaagtc attgatcacg atatctgctg aaattggata
    62161 acgatcaaaa aatctcgtta atacattgtt ccatacttcg ccgaagccat cgcttcctgt
    62221 acaaattttt acagtagatt ctgttttttc tgttggaaac atcaagattt ccaaatctcc
    62281 tgaaccgacc actcctacat ggattttctt attgatcggc tgtttcgttg gatatttata
    62341 agctaattgt tccatggatc tctccccttt ttgtaaaaca gagcatacac gttctgctta
    62401 ttcgtctttc ttcttccatc tgggtaaatg gcgacaaaag gtttttctcg ccaattttat
    62461 gaccaagttc tgaatttcat tggtggttca tacaggccat ctgaccattc gatcaaatca
    62521 tcgatggttt gtgcagctaa taatgaacgt ttcgcttcac tacgtttgat gcctagatct
    62581 tctggtaatt tcacgatgcc ggctgcacgc aagctatcta gtgattcttt cgtgctagtc
    62641 attccaagag gtgtaacacc gccaattgct gcaattgctg cttgtcgttc ttcttttgtt
    62701 tttgctttgt acaaataagc aattccttct tctgtcacga tatgtgtagt atcttcgcta
    62761 taaatcatca ctggtgcatt ggctaagcct gcttgttttt gaacagctag tgcatctaat
    62821 tcttcgacaa agactggttt tttatttgaa ccatatgttt caaccatttg aacaactaat
    62881 ttttggcctt tccctaatgg atcatcattg tcgcgaagtg attgccatgc tggtgtagaa
    62941 tgacgacgac cgccaggatt atgtcccatg ttaggcgcac cgccaaaacc agataaacgt
    63001 ccttttgtta cggtagaaga gtttccttcg taatctaatt gcaaggttga accgataaac
    63061 atatcgatgg catattgtcc tgcagcttgt gataatgttc ggttactgcg catcgtgccg
    63121 tctttaccga caaaaaagac atctgggcga gcagcaatat atttttccat accaacttcg
    63181 ccaccaaaac tatggatgct ttcaacccaa cctgattcga tggctggaat catcgttgga
    63241 tgtgggttca atacccagtt cttcgcgatt ttccctttta accctagtga ttcaccataa
    63301 gttggcagta acaattcgat agctgctgta ttgaatccaa taccgtgatt caaagattgt
    63361 acgccgtgtt ctgcgtagat tcctttgatt gccatcattg ccattagaat ttgcaattct
    63421 gtgatgtttt gaggatctcg tgtgaataaa gcttctaatt gataaggttt atctgctttc
    63481 acgacaacgt ctacccagtc accagggata tctacacgtg gtaaagaatc gacaacttcg
    63541 ttaacttgaa cgatcacgat accatctttg aaagctgcag cttcgatgat tgttggtgtt
    63601 tcttccgtat tgaaacctgt gtacaagttg ccgtctttat ctgctttatc tgcagctact
    63661 aaaacaacat ttggaatcaa atcgatgaat aagcgtccat aaagttccaa ataagtatgg
    63721 atatcaccta atttcattgt gccgtcttca atcatttggg cgacacgcaa gctttgtgca
    63781 ccagcataag agaaatcgat cttgcttgcg attccttttt caaaaatatt caaatgttct
    63841 ggtcgtgaga tactagacat gatcaaatgc agatcattca ctttttctgc atctactttt
    63901 tcaagacttt ctgaaagaaa acttgcttgt ttttgattgt cgccttctaa tacaactttg
    63961 tcgccgggag caatcagttt ttccattact tctacgattt tttcagtttc tacatacttg
    64021 ccattgagca agttgctgat tttttccaat cgctgcgctt ttttttcgcg tttagaagcc
    64081 cagttgcggt ttggtttttc cataattagt catctccatt tttgatatag aaacgtggcg
    64141 tcatcaatac catgttggtc tagattgatc gtacggatcc ctttatctac accaaatttt
    64201 gtatgaatca gctttgtcaa agtattgccg gggggaaatt caatcgtcag atccattcct
    64261 aattcttttg ccaagtccat catttggttc cactgcacag ggaaagctag gttttccaac
    64321 aaatctttac gaatctcttc tgcgtcctga gtggctcttc catccgtatt ttttatatac
    64381 aaacatctag catcagatag atggacagac tgcatatacg gcttgaattt cttgaccgta
    64441 tcattcatca agagacagtg agatggcaca gggactttca gcagcttcgc tgtttgcgct
    64501 tggtgccgtt tggcttctgc caacgtaacg gataaacctt cgatactccc agataacgta
    64561 tgttgcatcg gacaattttc atttgacaga taaactggat ggtcaggatc aaatgttttt
    64621 gctacaattt cctcagcttc gcttctcgtc acacctacta ctacgcccat tgcataaccg
    64681 cttggataag cttctttcat taagactgcg cggtgataga ctagttccgc tgcattctca
    64741 aatctcaaag atcgacaagc aacagctgca caaaaagcac caatcgaatg tcctgctgca
    64801 atatcaggct gaataccgtt tttttccatt tcatctaaat aaaatactgc ttttgtcagt
    64861 aatgctagct ggataaaaac cgtatcttga tagttttctt ctttatcaac taaccgatac
    64921 cccgtcacat tttctaaacg ttccatgtac atttcaggga tatccgctaa catccctaac
    64981 ttctgactgc cttgtccagg aaataagaaa cctgtactca tgagcctcgc ctcctcagca
    65041 cttacttttt ccactgctat cttagtcaat ttctgctata ataaaaaatg ccaaaaaaag
    65101 aaaaaaccat aacaaaaagg tatggatggg atggataatt atgaaattgc ttcatctgca
    65161 gtattttaaa aaagtattcg aaacaaaaaa tgttacccaa gcagccaaag aattatttat
    65221 ttctcaacct gccttgagcc gtgcgatcaa acatttggaa aacgaattag gtgtcccttt
    65281 gttttaccat agcggcagaa acattgagac gaccgtttat gcagaagaat tttatccata
    65341 tgcagtcaag acattagaca cattagaaga aggaatcaaa ttattgtctt cggtcaatga
    65401 gaagatcgtt acttccgtca tattgtattt agaggtagcc tctgtttcta ttccgaactt
    65461 ggtccgaatt tttatggaaa agcatcctga tatccaatta acgatcatgc aacatcattt
    65521 accagatgat attaccgatc ctgtactgta catcacttcg gagatgaagc ctggcatgac
    65581 caatattcct atcatgaaag aacctgttta tgtcgccatt cctaagaaac atcctcttgc
    65641 taaaaaagaa catctgcaat tagaagatat ccaacgcacc cccatcttga tgctgtcaaa
    65701 gagcaacgcc ttccgtcata cactggatgc agcacttgaa gcgaaaagta tcgaattgac
    65761 gatcagttcg acgacagatg atcctgcgac attacgttct attgtcaagc aaggattagc
    65821 tgttagcttt ttcccaaaag tttcttggtc ttacgataaa aatgatcctt tcgtcttgcg
    65881 ggaaatcaaa gatttgccct tgacacgaac aatttattta tcttctagct tcacagaaga
    65941 tcatcctttg atcaaaatga ttgcaaaaac gatgcgggaa ttttatttag gaaaataaaa
    66001 aaaaaagagc tgggacaaaa ttcttgtcgc agctcttttt tcgaacaaac ggtgttccag
    66061 aagtaatttc ttagaaaata agccgaaatt tcccaaaaat ttgagaagca attttcgtaa
    66121 attccttctt atttcttgaa gctaaacatt tctgtcacaa cctcttctct attgtcctag
    66181 acattcattg cgttgattta aaacttccat caatcaaatc tgctagttca tctagctttt
    66241 ctattttacg tagatcaata gagatccaat gttctttatt catgtgatag gctggaaaat
    66301 acccctcttt tcctcgcaaa attccgccaa gttcaggatc gaccttcaaa tcaagaatat
    66361 tgatgatcct atggtcactt gcatcatcat agattttttc ttctggaaca gacatcagga
    66421 ccccaaacca ttttttgctt ttttgatgtc tgaatacgca ataatcagga aattttttaa
    66481 aaatatattc tggagacaaa ttgtatgttt cattgatgtg atcgattagt tcttttttcg
    66541 ttagcatctg cttccatctc tttcttattg attcgcttta ttcaaagata ccacgtaaga
    66601 atagaaaaat gaatacaagt agttgctaat caaatacttc gatatttttc ttttttatca
    66661 actcttaaat gttcaatccg cctgtgttgg tcttgctacc atctactatt aaaatgttta
    66721 ttattgtttg cccacctatt ttttgatttt agtggtatca tttttcaagt tcatgatgaa
    66781 attcttatca tcagtaaatg ctccagaaaa ataaacaatg attgaaaaat cagttgaaac
    66841 ttgaccaccg tttattttct ccgtattctt agaatagaag ggagtctgat tgatgtattc
    66901 actaatgaaa aaaatcatta ccgaaaaaga tattcgacgt catgtttctt tagtagaaca
    66961 attgctgaat catacaaaga taaccgtaaa tgaattagct gaaatcatag ggacaaccga
    67021 acgaacgatt ttttctgacc ttcaatctat tcgctctcag ctgcccgaag gctgggacat
    67081 catcagcgat caagcaggaa tcagtttgca aaaccagcaa aatttattaa caaatgacct
    67141 ttgggagatt tttttcaaac aatcagtcag tgtcgaactg ctgaaaaatc tgctttttac
    67201 aaaaaaagtt gctgtccctg attttctagc cgaccatggg ctttcttatg ggacattgaa
    67261 aagacatgtg actaaaatca atcagcgttt agcaagttac gacttgcaga tcgatttgac
    67321 gaaatataca gcttgtattc ttggaaaaga gcgtgcgatt cgtacttttt atcatcgatt
    67381 gctgattcct ttcactcata acaactattt tttcgaggat tattcgatcc atgaatccca
    67441 ttattttcaa tttttaagaa acctcagtca aactgaacta gcggttgaaa cagaagagat
    67501 tttcggaaca tgttggttct ttatcaatac gatccgtata aaagcgaatt gccgattaga
    67561 ttcttctatc cataccaaca gcacactctc ctccctgtat gactctgcat tgaaaaaatt
    67621 gtatttaacg gaaggtattt atcttaaaga cactgagctt tcttttgctt ctttctgctt
    67681 tctggaaagt tggaattaca acaataacta tggacaagaa accgctcgct gcctgcatca
    67741 ttctccattt ttagaggtcc tcgaaacgtt tgtagaggaa ctagcttcag agctgtctct
    67801 tgatcaacta aaaaaaacat ctctgactga taacttggct ctcctcatat taaaatatca
    67861 tgaatcgccg atattgattg aagcattgga ccgtcaatac catcgttttt tagaaacata
    67921 tgatcagcaa tatgcacact tgtatcaaca gaaagagaat ttactgaacg atctaaaaaa
    67981 agaaatagaa atcaatgaac caaattactt tctccaactc ttgtctctac tgatccaaca
    68041 aacgattttt tctatcaaac cgaatttgtt caatgtctat tttattttcc aaggagaacc
    68101 ttcatggaag gcgttcttgc agcaggaatt aaaagattac ttaggaaaac gtgtctgctt
    68161 cttacctatc gaactaaccg atctttccac tatttctttt gaaaaaacag atatcttgat
    68221 ttccaatttc cctctagatt ctctagatat ccctattgta tacatttctt ctattccaac
    68281 gaaaaatgag ctcaatcgtt tgactgaact cactttcaaa acttttttat agtaacggct
    68341 agcgactgta ttctctagct gttttttctt ttttgcgaaa cagtttgttc atgatccctt
    68401 tttctatttc tacaactaag aatagaagaa tcacatttgc tccaatcaat aactgttgtg
    68461 tcatcgttaa acttactgta ccgatcagct gctggccgac tggtagaaaa ataaccatcc
    68521 cttgcaataa agcaaggata cctaatgaaa gaaaaagcgc tttgttttgc aaaagacctt
    68581 ggttcaatga cggcttggac aactctctgc aattgatcat gtaaacagct tgagctaaga
    68641 cgatattttg cagaagaatg gtttgctgta agctttgccc ttcaaactgc atagccaata
    68701 aataggcagg aaccatgatc agtagggaga catagatgat ccgaaacaaa tgataaccag
    68761 ataggattcc ttgctttgga tctcttggtg ggcgcttcat gatttctgga tctggcgact
    68821 cgaaccctag tgcataagat aaagtgattg tcgttaccat attgacccat aaaatctgta
    68881 ctggggacaa aggtagcggg cgattcagca taagtgccca aatcaagatc aatccttgag
    68941 ctaatgcagt tggcaagaag aaattgatgg ttttttgcaa attatccaaa atccgccggc
    69001 cctcttttac ggcttttgca atcgtatgga aattatcatc tcctaaaacc atatcagctg
    69061 cctgtttgct tacttcacta cctttgattc ccatagcaat tcctacatcg gatcttttca
    69121 aagcaggtgc atcatttacg ccgtctccgg tcattccgac gatttctcca tttttctgca
    69181 aagctttaac aattcgcagt ttatgttctg gtgtcgttcg agcaaagaca tcgactattg
    69241 gcacttgctg aatcaactct tcatcagaca taagatccaa atcgatccct tctaaaactt
    69301 tggcagtatg ttttaagcca atttgttccg caatcgcttt tgctgtgtct ttgtgatccc
    69361 ctgtaatcat tttcactgag atccctgctt gttggcattc ctttacagct ttgactgcac
    69421 tttcttttgg cggatcgatc aatccggcga tccctgcaaa agttaattgg gttaaagtct
    69481 catgcgtgag ttcctgtttc gaatctactt ttttataagc aaatcctaaa acacgctgac
    69541 cttttctcgc aaattctgca gctgtctgac tccatgcttc ttgttctgca gaagaaagag
    69601 ttgatttagc aaataatact tctggtgcac ctttgacgta aatcaccgct cctttttcct
    69661 ccgcatgcat cgttgccata tatttgtatt cagaactgaa cggaatcttt gcttctattt
    69721 ttttcaaagg tagattggct gtttctgtgt gtcgaatcag cgcaacttct gtcggattgc
    69781 cacttaaatt ttctgttttc tgttcttctt ttgtttttaa ttcctgacag tttttcataa
    69841 tggacaacac gcaggcttct tcttttgcag ctacatccac aactgtcatt tcattttttg
    69901 tcaatgttcc tgtcttatct gaacagatca ctgtcataga acctaatgtt tctaccgaag
    69961 gaagtccttt gatgatcgcc ttttcttttg ccatttcatg tactccaacg gatagaatca
    70021 tggtcaaaac agctggcaat ccttcgggta ccattgacac caccaaagca atcgtagccg
    70081 aaagaagaat atgccaatcc ataccatatc gaaatgtcgt aaaaataact aagaataggc
    70141 tcaaacaaag aatgccttga aaaatttgtt tgtttaatcg gttgattttt ttaatcagag
    70201 gcgtcgtttg ttgttcgacc gattgcaatg cttgattgat tttaccgatt tctgtcgtgt
    70261 ttcctgtttc tacaacgaca ccgactgcag aaccagattg tacaagcgtt cctgaaaaac
    70321 ccatattttt ctggtcgccg atcgattctt cttctgtcaa aacggcatga cttttttcag
    70381 atgcttctga ttctcccgtc aaaatcgatt cttccactaa taaatcatgt gcttcgatta
    70441 atcggatatc tgctggaacg acatctccgg cacgtaagac aatgacatct ccttttacca
    70501 gttctttcgc agggattttt tcttgcatcc cgtttgatag tactatcgct tcttgtccca
    70561 tcagctgctt caaaccattc aatgattctt ccgcttttct ttcttgccag taactaacga
    70621 gtccattgac gatcactacg aataaaataa tacttccttc aatatattca ctagaagcaa
    70681 atttcaaaaa agaggcaatg atcaacacga tcatcagcag atcagtaaaa tgctttgcta
    70741 tttttttcca tcgttttgtc tgctgccttg cttttatttc attatatcct tgatcagtca
    70801 ggcgtttctg tcgttcttct tgcgacaagc cttctgttga tgtttgatag tttttcaata
    70861 catcttctac cgtcaatctg taccagttca tcctatcccc tcctgtttaa ttgatactgt
    70921 tattatacgc agggaagttt tttcaggcgt atcgattatt tcaggggggt ctgaaataat
    70981 tcgttttgca aaatgtatct gggcctaact gatatttcta ttgcttattc ttttatatac
    71041 aaaatttaag aatacaaacc agataaccaa taaaaaagga ataaagcgtg tcgtgctttc
    71101 gaataacaag ctgaaagcaa ttgaagtaaa aaacaccaac aaagcaagat ctttatatct
    71161 ttgtgtagtg ttccgtttct tttctttaat aaattgaaca tgtgcacaca agatcgaaga
    71221 ccacacaaat agaaaacaac tcgttgtcat gcctgccaaa agctgaaaaa acaatcgact
    71281 atcagctaca aaaaaatgta gacaaagacc ggcaaaaaat aacattcctg taattaaaat
    71341 accgtgtaaa ggtacgcctt tcttagaaag cgcacaaaac caatggggca aacttttttc
    71401 ttttgctgtt tgatataaaa tcctgctagt actgtagact gcactatttg ctgaggacaa
    71461 agaagcaacc aaaatcatta gattgacaat tgctgctccg ccttggcaat ggatcacttg
    71521 cagcatagtc actaaaggac tttcttttaa atctaaacaa tgccatggaa caacaaataa
    71581 aatcgacaaa atcgttccta tatagaaaaa gagaatacgc caaggcagac agttgattgc
    71641 ttttttcaaa ttcttttgcg gatcacttgt ctcgccaacg gttaagccga tcatttcaat
    71701 tccagcaaaa ctgaataaaa ccataggaaa tgagactacc attccagcaa agccaaacgg
    71761 tagtaattca tcgatctgtc caaaattttc tttgattccg atagactggg tatgaaaatc
    71821 tgagacactc aatcctatac ccaataagat aaaaaggaaa atccccaaga tcttgatgat
    71881 tgagaaaaaa gattccaatt caccaaacca cttgactgca acaaggttga ctgccattaa
    71941 gatcattagt gcgctacctc cgcttatcaa agctggtaca tgtacaaacc agaaatggat
    72001 atacaatcct attgctgtta attccgcaag tccagctcca agccagcaaa gccaataagt
    72061 ccaattgaca aaaaatgccc actttttgcc taaataatag tcaacgaaat cactgataga
    72121 gttaaatgta ctatttgcta aaaataaatc acccatggcc cgcatcaaac cataaatagc
    72181 caaaccgcat atcaaataaa cgagaataac agctggccct gctgatgcaa ttgcctttgc
    72241 tgaacctaaa aataatcctg ttccaattgc gccacctaat gcgattaact ggatatttcg
    72301 attagttaga gtccgtttca ttgccggttt ttccatcaag ttcacctttt tctttttcaa
    72361 gcagcatggc gacttcctgt tcccaagaag gtttctttat tttttcaata cagagtggta
    72421 ctacaaacaa aatgacactg atggctgtga ctgcaattag attgatccat gttccagctt
    72481 tcatcgtcag tccgacagaa aatccgattg ccgcaaataa aacaataacg acagtccaaa
    72541 ctccaagatt gctctttttc tctttttttc caattctaaa tggtcgattc aactttgcat
    72601 gtgtataacg caatctcaaa actgcgatcc ccatgatgac atagacgata cagtagataa
    72661 cagtagttga atttacgagc atcaaaaatg cttgattgac gccaggaatc agcaaataaa
    72721 aaagtgcaaa gattgagata atgacagact gagtcaaaat aacggatttg gatacgtcaa
    72781 attgattcgt cttccaaaaa ttgaattttg gtggatacgc accttttcta gcactttctg
    72841 tcactgtctt tgctggtcct gaggcccaag cagataattg gactgctaca ccaatgaaga
    72901 caagtaaact aaacagattc acaataagat gtggcaaacc aagaatttgg caataaatcg
    72961 aaatagattg cgcgatatta ttcaattcca tttgtccttt tggtacgaca tttgctacaa
    73021 ctaaagcatt caaaatattg acgaaaaata taaaaattaa cgcggcaaat actccgcgaa
    73081 tatacgtttt aactggattt tccaatcgag tgatatacac agaggacatt tcgataccag
    73141 taaaaataaa catgatcggc gcaaaataaa caaatgagga tgcagtcgta gtatctggta
    73201 ttaatttgtc ccatgaaaaa ctgcctaatg ttccggttgg tacgatccca actttgatcc
    73261 acgcagcaaa ccctaataag agcatcatcg tcaaaggcac gtacaatcct aaccaaacac
    73321 cgacttttcc gccgattttt gccatatcaa atttcaaatt caaaaaagtg atgatccaat
    73381 aaacgactaa aatgacaact aatgtaaatt tgctgttcaa accaagcggc acattatcga
    73441 taatattacc aaacaacgga gcgagtgctg aagcgaccat caccatccca ggaaacattt
    73501 ggacccataa cagccatgag acaacgaacc cccatttttt tcctagagca ttcgataccc
    73561 aaagttctgg accacctttt tggggaaaca ttccagcaaa ttcaccagag atcaatgaga
    73621 ttggaaaagc gtacaataat actgcaacca gcatgtaaaa aatcatcgtc cagctcgttg
    73681 ctgctacatc tggaatattt cgtacacttg ctacaagggc gcaggtcatt ccgataaagg
    73741 tcatggtcgt gatttgcttt gatgaaccag tatctttcat ctttattcct tctttcaata
    73801 gcgacatatg tttttgtttt cttttatttt tgttcaagaa cagaaatgac aaggtttcat
    73861 cgattcagta caaaacccag tatcaccgaa acatccattg aacgatctta gtgaactggg
    73921 tttgatacat gaaacgaacg atccaactta tagaacgttt tataaaaaag aatatcttgg
    73981 cgaggaatat atgaaaaaca gggggaaata caattgtttt gatgaagcaa ataattgtct
    74041 gttctccata tgtctcttgt tattctttca cacaaaaatc agttctattg gatgatttcg
    74101 tttagtttct tttccattgc tttggcgatt ttttttgtat aaaaattgaa aattcgatca
    74161 tcattcaaat aaggagtcat gatagccgca cgtagcagag tgattttctg ttcttttttc
    74221 cattcttctt tcgttagacc cattctttca acaaaacgaa tcggagaatc accgtaatct
    74281 tcttgtgtaa atgtagtatg agaagtaata aaccgttcac cataaacatc gccatccata
    74341 taagaagacc gatcgaacat tttttcattt aattcattga tagcgttcaa atctgtacag
    74401 ccttgttctt tgaataccca attgaccata ttaaaatcag gatgattcaa tggatagact
    74461 tcgattgttt ttcctttaac agtaaaagtc agatgatcga gaaattctct gaatctttga
    74521 gctgcctcga ttgaagcccc aatcaattga ccatatccgg tcacattcaa tggcaataca
    74581 cgatgtgctg tccagactgc ggcggcggtt gctccagctt ttgatccttc caaaatataa
    74641 gctcctaaca tatctggagc ctttactgat ttttcaaaca catatggcgc gaaataagaa
    74701 atgatatttc tcatattttt atgtttgatt acgattcctc cagcagcata agggacatag
    74761 cccatcttat gaggatctat cgtgacagaa tccgcttctg aaatagctct gaacccttca
    74821 tatacctctt tgtcaatcgt tacgcagtgg tggaaaacat gatgttcttc aaagaattca
    74881 gctaaggaag catacggcac aaattctcct gcttcgttta gaaacagtga acgcgcatag
    74941 ccgccatatg cggcatcaac atgtaaatag aaatagatcc cttcatcttt taacctttct
    75001 cttaattgga cgattttatc tacactgtct acttgacctt cttctgtcgt tcctacgaca
    75061 gcaaccacac ctagaattgg gattttttgt ccagctaatt cacgaattgt tttttccaaa
    75121 gcattaatat ccattcgata atcctcttga actgggatag caaccatctg atctaagccg
    75181 actccgcaaa tatctaacgc cttcatccaa gaatagtgtt ttgtttgagg gaccagccat
    75241 ttccctaatc tttggatatt ttttccgcta cgggaagaag ctgctttgac ctcatccatt
    75301 tcttcgtccg taaagctttc ggtcatttcc aaaatttctt caacagataa attcaaaagt
    75361 tcccactcag acattttttt cactttttca ggcagcactt ccttgacagc taaaggaatc
    75421 gatttgatgc aacgggcgta ccataatcct tcaagattag caatagaacc atctgctgca
    75481 atgtgtcccc atccgtctgt catattgaat aatgaagcaa aatcctgtcc tacttctgct
    75541 tccatttgcg aagttgccat agaagattcc aatgcaacat tatttgggtt ccacagcatc
    75601 gcatagttgt aagctaataa agcaggcatc aatgtttcag cattcatttg tccccagtaa
    75661 cggcctgctg aatgccatgg gatcgatcct gcgcgtaatc gctgactgac ttcatccaag
    75721 acctctatca tatggtcgcg ggtggctaga taatctggag tgagcttatc tccttcgcta
    75781 attgcaggca tatctgaagg aatataattt tctctccatc caagatgttc atctaccatc
    75841 ttgttcaaca acattttata aactggtcca ttttcagctt tgtcgcctat aaagacggcc
    75901 ttgatatcca tatctttcat ttttcttccc tccatatttt gttggtcaat gtcttgcaga
    75961 tacatgtgtt tatctgtaac acctcttcac tatagcgcca aaaatgagaa tttttttttt
    76021 ataacatcaa atccacgtag atttttacaa acaaaaataa ataaagtcgg atttttctga
    76081 taattcaacg caaaaaagcg aacaattttt caataaatca gtcttctaaa atagataacc
    76141 taaaaaaagc gaacaaacaa ataaaatgac tgtccttcat tcactaaaca tatttttatt
    76201 tttttatatt gttaaaaatt cgcaatttat tttttaatag aattatctgt tttccaaatt
    76261 ttataacata aaaaaccttt tttaacggca tttatatgct ttttcagaaa ttaactgatg
    76321 atttcaaaaa gaaaacatgt cataatattt cccatattgt gcaaaaaaat acaaggcgga
    76381 ggctctacta tgattgaaga atatattgag aaaaatattt taagacagct gtttttatgt
    76441 gggcaattct atgtaaataa agaagtcaat ctagaaaagc tctccaatct cctgcatgtt
    76501 tgcaaaacca ctttactcaa tgatatcaat aacataaaaa aagaatttga agaacagatc
    76561 gcttatacac atcgggaaaa ggaccgttac actttatatt tttcagaaca tatacctcga
    76621 tgcaagatca tgcagcaatt gtctcaaaat tcgttgtttt taaaaacttg tctgctttat
    76681 ttggaagaag atgaacctga ttatcttcaa ttaactgaat gtgaattcat ctctgtcagc
    76741 aaagcttatt cattaaaaaa acaagtatta gcttatttta atgactgcgg gatcgaaatc
    76801 gaccgctact cccctcgatt cactgaaatg gaaagacgtc tgctgcttct taatgtgtcg
    76861 tatcgtttag gcggttttaa ttcttgggag ctacctgaat cgttttttga acgtgccgat
    76921 cgtttcattg aatccgtaac ggaaaatagt ggcagatttt atgataaaga aaataaagaa
    76981 atcttatcga ttggttttgc tatcagtttc ctacgccagc aagtgtgtgc tgtgacaata
    77041 gattcaaaat ttatcgaaga aatcaaaaaa cgtcctattt acaattatgt cgaatcagca
    77101 tgggaaaaca ctgatttcca aacctattat aaaaaagaag aattcgcctt tattttgaca
    77161 ctattcaatc tttgtaatta tggtttccat tcttatcagt tgattgcgga agactttcaa
    77221 cagctacacc aagtgtttat tgacaatact cccgaaataa aagaactagt tgctaccttt
    77281 gaatctcact tcaatcaaga attattcgga aaccaaccgt tcgaacgtgc gctgattcat
    77341 ctgatgcgtt cggcttggga taactatcaa ttattcatgc cagaaaaatt ttatctttta
    77401 aatgaggaac agacaaattt atataaagaa gtccagacaa ttttttccag ctggtccagc
    77461 cagttacctt atgatctacg gttgaatcct aattgcatgc gggcttttgt gatcgaattg
    77521 agcggaattc tccgtctgac aaaagaacat ctgactatct atatcgtcac aaattcggat
    77581 gttcattatc tgatttatcg ggaagccttg gaagctgtaa ctactttcga ttttcaagtt
    77641 gcaccaacaa tttattcaag tatatctgat ataaagaagt atgcgcagca gtcctcaaac
    77701 cgggtattat gtgaacgtac attatataca ccagatgcgg tccaatatga aaatattatt
    77761 cctatttcga tcaatacgat cgatcgagct atcatttcag ctgtgcaaaa caaataaggg
    77821 gctgtgacaa aaatcatgtc acagcctctt atttgttgaa gatgcccatt tctgtaacaa
    77881 tctcttgata cacgtcaggc tcacaacctc acttattttg gacatctacg ggtccgatct
    77941 ctttatttaa aaaataagaa atgatggttc ggataactac caacgccgct agttggaaaa
    78001 tatcctgcaa ggtaggtttg ataatcgatt cgatgatccc agctgaaaca agaatttcca
    78061 aacttagaag tatatagcct cccaacatct ttttaatagc attgttctcg ctgactcggt
    78121 cgctttgcac ttttgtatgg acaaataaat atttcaaaaa atccttgatt gatagacaaa
    78181 caccccaaac caataaacag atagcaaaga tatcaagtcc cagtacaagt ttttcgaaat
    78241 atggaagaag aaactgcatc aactctgtcg tcatcctacc tctcctcttc tttgtttttc
    78301 tttgtcttct atttcctgat tcaagaaata agaaatgact gttcgaatga taataataag
    78361 tgcaagcttc aaaatatctg tccaagtcgg cttgataact gactcgatga tatcagcaac
    78421 gactagtact tccaagctta acaaaatata acttgctagc agttttcttg tatctgcatt
    78481 acgagtatta cgttctgcat agtttttctt gacatgagac caatcaaaaa gtttgaatag
    78541 aacaagaacg atcccgacaa ttaagatacc gatagaacaa atatttaaaa tagcaatgat
    78601 ccattctaga aattcaatta aatttgagcg aaacatatac gctacctact ttcttttaat
    78661 ttgttcctat tcttttattg taaaagaaag ttaccttgtt cgtctattta aaagttgttc
    78721 taatgataac ggttcgctta aatttttctt tttcactctc ccatttttct ccctccatcc
    78781 ataaatcgtg gaagtatcca aaacaacgta gcaagttaaa ataaggctta gtccgtcatc
    78841 agcttttcaa agaagcactg tctcggtgct ttttttgtac ccaaatttct aaaaatagaa
    78901 ccatacacct cctcaaatct tttcttctta cctaccctat ttttatttac aggaaaatca
    78961 gacacttctt cttttttgtc aaaatttcct ttttcttctc gtcctatcat ttggcattct
    79021 aataaaaacg aactatcctt ggatatagaa agagaaaaca aggaggcgtt tttcatgagt
    79081 aaaaaattaa tcaaagtcgg catcggttta ggtttgcttg cccttggcgc tgcatatcta
    79141 ggaaaaaaga caggactatt cgaagatgac agtcatttat atgatgaatt cgaatcaatc
    79201 tagcatccta tttagttgaa tcactacgga catacttgga agacattgga ggaatcacaa
    79261 tgagaaaaag taaagcaata atgattggtg ccggtattgc caatatggca gcggctgttt
    79321 atttgattca agaaggcaaa tggaaagggg atcagatcac cttttattca ttggatgatc
    79381 acggttcaaa tgatggtgca ccgaccgaca ctgtagtgga tgaatattgg aataaaaacc
    79441 atccattaga aaaccaaaaa ggctatattg ctcgaggcgg tcgcatgctt aattaccgta
    79501 cctatgtaga tttgatggat ctgttaagtc gaataccttc tgttactgag ccagggatga
    79561 ctgctgaaga agatacgaga gattttgatg caaaacaccg aacctttgac aaagcacgtt
    79621 tgatggaagg tggcaaagga atcattgatg gcggaaaact gggattcaat aataaagacc
    79681 gtattcttct gactaaactg attgctatgc ctgattcaga agaagaaaaa ctagacaata
    79741 tcactatcga agaatatttc aaagatgatc cacacttttt tgaaacaaac ttctggttta
    79801 tgtgggaaac aacatttgct ttcagaacac gtagttctgc tcaagaattg cgtcgctata
    79861 tgcatcaaat gatttatgaa ttcactcaaa tcgaacatct agtgggcgtc aatcgaacac
    79921 gttacaatca atacgaaagt attatgcttc ctttgatcga gtacttgaaa gaacaaggat
    79981 gcaaaatcat tttgaaccgc cgtgtcactg actgggaatt caaagaaaca ccgatgcaag
    80041 atgaaatcac tgtgactggt ttgaaaatta ccaatacact gactcaagaa gaagaatacg
    80101 ttgtggtcga tgaagataca gcagttattt tcactaatgg gtccattaca gattcagcta
    80161 ctttaggaga ttacgaaaca ccagctgtag aaaatatgga ttatggtgca gcttctagtc
    80221 tctggaaaaa agccagtgaa cgtttctaca acttgggaaa tcctgacaaa ttctttgctg
    80281 atcgagatgc aagcgaatgg gtcagcttta ccctgacgac gaaaaaccat ttgttgttga
    80341 atgaaatcac ccgtatcacg actcaagaac caggaaatgc cttgaattca tttatttcaa
    80401 ccacaccgat cacgccgtta ggccaaaaag atgtcaatat gtctatcgtc gtgcatcatc
    80461 aaccgcattt tacgtctcag aaaccaaatg aaacagttat ttggggttat ttcctttatc
    80521 caagacgacg tggcgaattt gtggataaac agtatattaa aatgaatgga aaagaaatgc
    80581 tagaagaact gattggacaa ctttcaaaag tagatcctgg accagtgaat attcgtgaaa
    80641 aagaaacaga aattttcgac agcgtaataa ataatatccc tgtctatatg ccttatgctt
    80701 ccgcgttgtt caataatcgt gccaaaagcg atcgaccaaa agtcattcct aaacattcga
    80761 ccaatctggc ctttacagga gaatttgtcg agcagcctta tcagatgatc tttactgaac
    80821 aaagtgctgt acgttctgga gaaatcgctg ctttccattt tgcgggtatt cctatgtccc
    80881 gtcttgtcaa aacaccgcgt tacgacaaag atattcctac tctagctcgt gccgcaaaaa
    80941 aaatgtttga ataatcaaga ggttgtgaaa aagctgccct gcatcaagta ataagaacaa
    81001 ccaggctaaa acagcttctt atgtttttga tttggttgga cttattaccg cagatgcaag
    81061 cttttgaaca ccgtttacca agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa
    81121 cacccaagct aaaactgctt cttatgtttt tgacttggtt ggacttatta ccgcagatgc
    81181 aagcttttga acaccattta ccaagaggtt atgaaaaagc tgccctgcat caagtaataa
    81241 gagcagccaa gctaaaacag cttcttatgt ttttgacttg gttagactta ttaccgcaga
    81301 tgcaagcttt tgaacaccgt ttaccaagag gttatgaaaa aggcgtttag tttcgagtat
    81361 gaagaaaaat tttgtgaaaa tggttcctca cgtttttgca taaatttgac ttaataccga
    81421 gaaactgatc ccttctgtca taacctcttt ttatttatgt ctgtttcttt ttgaaaacaa
    81481 ctattttttc aacgtttact ctcttgccaa tccaacatca tctaacggat acaactattt
    81541 caatgattac cattacacta aaaaatcgga aacacacctc tccgaacaca aatacataag
    81601 actatagaat gtttcattta agaaaaaaag cgtttcatta tcaaaaaggt aagatctcct
    81661 ttaaaatgaa attatctgta gtactaataa tgcagacaat tttatgaatc tgaaaggagc
    81721 atctccaatg aaagcagtca cttggcaagg aaaacagaaa atggaaatca gaaacgtaga
    81781 tgatccaaaa atattagaac caacagatgc aatcatccgt atcacagcaa cagccatttg
    81841 cggctccgat ctgcatcttt accatcatgg tgaagcagtt ttggaaaaag ggtatgttgt
    81901 aggacacgaa ccaatgggaa tcgttgaaga agtgggatct caagttcaaa cattgaaaaa
    81961 agggcaacgt gtggttatcc cttttaatat tagttgtggt cattgtcatt tctgcctgaa
    82021 tcacatggaa agccaatgtg atgaatcaaa tccagatcag ttatatggcg ggcttttcgg
    82081 atttggcaag ttgaacggta atcattgggg tggtcaagcg gaatatctaa gagttcctta
    82141 tgcagactct acttcatttg ttgtaccaga taatgatctt cctgatgaaa aagttttatt
    82201 tctatcagat attttgccca cagcttattg gagcgttgaa aacgcaggag taaaaaaagg
    82261 cgatacagtt gtgattctag gttctggtcc agtcggtcta ttcgctcaaa aattcgctgt
    82321 tatggctgga gcagagcgcg taatcgcagt agatccagta cagcaccgtc tagataaagc
    82381 ggctaattac aatggggttg aaacttattt cttagaagac acggcacaag ctggaacaga
    82441 attgtatgaa ctggctaaag gtggcgcaga tgtcattatc gattgtgtag gaatggacgg
    82501 attagagcct gtcaaagaaa aagcgaaaaa tttagtaagc ttacaaagcg gcacaatctc
    82561 tccattacag atggcatcgc aagctgtcaa aaaatttgga acagtccaag taactggtgt
    82621 ttatatgact ccagcttctt cttacccgct gcaagaattt tttatgcggg atatcgctgt
    82681 caagcatgga caggcaccaa ttatccatct aatgccaaaa atttacgcaa tgattgcaga
    82741 aggactattc gatcctacac aaatcattac tcattcgctg ccactatcag aagcagcaca
    82801 agcatatgag atctttgaca aaaaagaaga taaaaatata aaagttgttt tgaaaccttg
    82861 aattcagtaa aaaatacagg tgattttctt tatgcccaaa atcaaacgaa atacccatga
    82921 gatcgaaata ggaaaagaag aagatatcga aatacgagga cgtcgcttcc gcttctattt
    82981 ccaaaatcgt tacacattga tctcactggc tgtcgattta ttaaccggga ttttctatat
    83041 ttttggaagc cttgcttcct taactaaaat ccccgatcga tatggcacct atttttattt
    83101 ggctggtgct attttcttga cgattcgtcc tattctcaga atcgtaagga acatttttat
    83161 ttacgacgaa aaaaaagcaa tgaagagaac aagcaaaaaa aaagaggcat gagaattttt
    83221 caaatctcat gcctcttttt tcaccctatc gtatcacttt gatacagacg agcggtcgtc
    83281 ccactttctt ccttgaccat tgtcaaaaat gtccactcgt atcgttcata aaacgtggta
    83341 tgatctgtaa ttaagtaaag tttttcgtac ccaagttgat gcatttcttt tctgatttcc
    83401 gctaatatcc gcttggctat cccctgctta cgcttttccg gttcaacaaa cagggcacaa
    83461 agatttggtg tcagatcagg gcggttatgg aagtcgtttt caatgacgcc cgctcctccg
    83521 acgatggttt ctttttcatc taagaccaca taccattgag gaatactttc cttattagcg
    83581 attccagtac gaatactttc ctcatacaca acagcaggaa ctccccattt tgatgaaaac
    83641 caattcgcgc tttgttttac taattctggg tgttctctta atttgatcca gttatatgta
    83701 accaatgttt aaacctccga ctaaaataaa acgtttacaa aaattataca agtctttatg
    83761 aaaattagca atgacaacaa tagtgatgta aaaaaaaaac ggaaaacaat cacttgttct
    83821 ccgttttttg attaatcaag catctaaagc ttcttttctt ctttcttgga tcgtagctac
    83881 cttgacgaac ggtagataga tcaaaataga aagaaccaaa ttgacagcgg ctagtacacc
    83941 acctgcaata ctttttgttg ccaatacacc gccaataatt ggtggagtta cccatggagg
    84001 cataacggta gctgctggca ctaaacctgt agaagtcgca aagtaagcaa cactaactaa
    84061 gaccattggt gtcaaaataa atggaatgaa catgatcggg ttcaacacga taggtaaccc
    84121 aaacatcgtt ggttcattaa tattgaagac acctggcgca atcgacaagt ttgttacaac
    84181 catatatggt ttgtttttac gtcctactaa ataaatagct aacagtaaac ctaaagttgc
    84241 acctgttcct cctaagttga caaagctgtc aaagaaaggt ttgttcacga taaacggtgc
    84301 gctatgccca gctgcgattg cattaacgtt tgcttcaatg gctggcgcat tgattgtttg
    84361 catcaaagga tcgaccatat tcgctccgtg taaaccaaag aaccataaga atggtgtgat
    84421 aaatgcaagc agtaaggcag atggataaga gtttgcaagt cccataaatg gttcttggac
    84481 cactgtatag aaagaaccta cgatatcatc aacaccgaat gcagcaaaaa ttgcagcaac
    84541 taaagcaaac gcagagatag tgatcattgc tggtagtaat gaagcaaatg cttttgcaac
    84601 tgccggtggc acaccatcag gcattttgat gatcaatttt tcatttccgc ttaaacgtac
    84661 aaagatttct gttgaaataa tcccaacaat aatagcaata aacaaaccgt ttgagctcat
    84721 acctaatgct ccgcctaaag cgaagaaaga gcctaaagaa atcacacctg cggaaacacc
    84781 gtcttttcgg tagccgttag ctaaatgata agcaagcaag aaagcaatca agacagaaag
    84841 aatggcaaat gtaccgttcc aagcagcagc cccgaatcct ttccatgatt caccaccaaa
    84901 aattgagttc atcaattctt ggaacccggg aatcggtaag ttattgatca ttactgctaa
    84961 tgctcctaag atcattaacg gcatactcac cataaatgag tcccgaatcg caactaaatg
    85021 ccgttgtgca ccaatttttg atgctacagg tataaaatgt ttctccataa atgcaacaaa
    85081 tttatccata aatcttccct cttttcttta ctgtagatta cgcgttcaat cgacgataca
    85141 gatcaatgat ctcttttgct aaatctgtaa aagctataga tgtcatcaga tgatcttgac
    85201 tgtggaccgt caaaagcgtg acttcaacgt gatttccttg tgcttcttgt gtcagcatct
    85261 ctgtttgaga gtgatgtgct tggactaaag attcctctgc atctttgatt ttttcatctg
    85321 ctaaagtgaa atcacctttt ttcgcagcag caatcgcttc cattgcatcg ctttttgcat
    85381 ttccgccaaa catgatcaga cccatgatgg cttctagatt tttttgatct tccatttatt
    85441 gtatcctccg ataattttta ttatttgttt attagttttt ctgcttggtc gagtactttt
    85501 tcaccattca tcatgccata gtcagccata ttgattacat ctaaaggaat gcctttaggt
    85561 gctagctttt cagcaaattg attttgcata aagcgtactt gcggtcctaa aagtaaaacg
    85621 tctacatttt tagattctag ttgattatcc gcatctgaag cagatacagc aaagatgtct
    85681 gcttccattc cttttgcttc tgctgccttt tgcatttttg tgactaggag acttgtactc
    85741 attccagctg aacatacaag catgattgtt ttcttttcca ttttaaacac gttcctttct
    85801 atacttacac ttgtatataa gcaagtagcg tgccaacttt aaaagcgctt taaaaagttg
    85861 atatcatcac atttaaggtc tataccaagt tgcatacaca ctaaaaaaga aagcgcacac
    85921 taaacacaca aattaatttt tattaccttt tttcttttaa cgtgcacaaa aaaagttgtg
    85981 acacaaaact tgtcacaact tttttcaaat aaacggtatt caaaagcttg catctgcggt
    86041 aataagtcca accaagttaa aaacataaga tgttgttttt actttgctat tcttattact
    86101 tgatgcagga cagctttttc acaacctctc aataaacggt gttcaatcag ctgaccctgg
    86161 gtattagctc aaaacgctgg attcacaacc tcttttattt caaataacca gtaaatacaa
    86221 tgaacatcta caaaaaactt ctatttattt atagatttcg tcaggcaaat ccaattctct
    86281 cttatcaatc aaagtctgat accacgaagc agattttttc aatgttctgc ttcgttcatc
    86341 gttcaattcg attcgaacta atccatatcg attcttaaat gcattcattg gtgacacaca
    86401 gtcagtgaat gcccataaca tatagccttc gcaatttgcg ccttcttctg ttgctttgat
    86461 caagtaatgc aaatgctgtc cgataaattc gatacggtaa tcatcttgca cgattccttt
    86521 ctcatccata tactgttctt catattctct tcccataccg ttttctgtta tcagccaagg
    86581 gatattatga taattttctt ttagatacat ggctatatca tacatgattt tcggatagat
    86641 ttcccatccc ctggaattat tcattttctt cccaggtaaa tcaaagactt cataatatcg
    86701 ttcaggatgg aaaggtgtct cttcattcca ttgataacga ggggcgcgaa cgcgtttagg
    86761 ataatattga ttgattccaa ggaaatctac tgtatgatgc tgaatcgttt ctaaatcctc
    86821 tgttgcagga tcgaaataaa tcgattgttt ttgacacaac tccaggaact cttctgtgta
    86881 gtatcctttt accatcggat caaaaaatac tcgattataa aacaaatcat acatataagc
    86941 agctttttgg tcttctggag aattggatcg agcatagacc atttcaggat ttaaaataca
    87001 gccaatcctt ccaccataat ttccgctgcg gtaaatctct actgctttag ccgttgctaa
    87061 aactttatga taattccaca tcatccactt ttttgtgttt tgttcatgcg gccagcgaac
    87121 agcatccaaa tagcaacgcg tttggggaac gattggttcg ttgaatgtaa accagttttt
    87181 taccctatca ccgtaacgat caaaggcaat ttgagcatac ttagcataaa aatcaactac
    87241 ttttcttgaa gaccagccat catatttttc caaaagaaaa gctgggactt cataatgttc
    87301 caaacaaatc atcggttcta cgtctgcttc gatcaaagag tcgatcattt cacttatatg
    87361 ctgagcatat tcttcatcta ctatacagtt ctcataatca gtaaaaaaac gagcccaatt
    87421 gatagaagtc cgataatgtg tcagatggat ggatttcatc agatccacat cctgctggta
    87481 ttgttccata aaattagttg ctacggctgg gccataccca ttatgccaaa caaaatgttc
    87541 atttttatac cagctatcta taaacgaatc ctgtccttct ttttttcctt tccaaccttc
    87601 cgtttgccaa gcagaagatg cagcaccaag aataaaattt tttggaatag taattttcat
    87661 gatttcctcc tgttttttag atcccatcat tttccacacg atttgctact tttacaaatg
    87721 gcagatagat caaaatagaa acaataatac aaacaagttg cgtaataact gcaccgatat
    87781 ttcctgctgt tgccagataa gcattgacga tcggcggcat tggccaaggg accattacaa
    87841 ctgctttcgc cgcaaatcct aaagcggttg caaaataacc aatcgttcca gtgataagag
    87901 gcgttaagat aaacggaata gctaaaattg gattcagcat gatcggcata ccaaaaataa
    87961 ctggttcatt gatgttgaag atcccaggag caagggataa cttggtgatt tgtttcatat
    88021 cttcccgttt tccaactaac aatactgcaa tcagtaaacc gatcgtgact ccagacccgc
    88081 ccatactcat atacatatcc caaaatggca tagtaataat gttcggtact tcttttccag
    88141 cttcaaaagc ttccgtattt acagcaattg ccgctaaaag caacggttcc cgtatcggct
    88201 tcaccatttg atttccatgg ataccaatca cccaaaagac ttgcgcaata aacatcaata
    88261 gcaaaatacc cggtaaccct tgtacgacac cttctaatgg gcgttgtacg acattgtaaa
    88321 tgatatcata aaggtacatt cctgtaagtt ctttgatgat aaatcccgca gccgcgatac
    88381 ccgatacagt cagaatcgtc gggaataaag cagaaaaact agcagaaaca ttcgttggca
    88441 cggtatcagg cattctcagc tgtagtttct tctgtttcct caaccagcaa taaagttcaa
    88501 tagaaaggat ggagaccaac attcccaaaa ataacccttt cgtatctgta tattgtttag
    88561 ccaatacgtt ttctactata acagtctgat tttcattcac taattcataa acagttggat
    88621 taacagataa ataagacatc actgcgatga taccagggaa tacaccatcc actttattca
    88681 gcttggctaa ttcgatccct atcagaaaaa cagcatagat ggtcaagaaa cttagtgtga
    88741 catagctgat ggcagatgcg ataggcttta attcttctaa aaaacgcaag aaacttatct
    88801 gtgctaagcc attttccgag tcaaagacca ttgctgaaaa caatgtgcca aaagcacccg
    88861 taataattac cggaatcaat gcagcaaatg cgttttttat caccatgata taccttaaat
    88921 tattgattct cgttgccacg ttccctaaaa cattggctaa tttatccata aaactcattc
    88981 cagatcccct cattcctgct tcttctcctt gacgtcatct ctttttgtct attagtcagc
    89041 gcttacattt cgatgaacag aaactattta ctcctctttt ttaccaaata taaaacaaaa
    89101 attcatctga tgtatttatc ataaaataca tcagatgaac tgtcaattag tttctttttc
    89161 tcctattatt ttctgtaatt ctctccgatt tattgccata tggacagtca ttgcatcaaa
    89221 cgcagcaagt gcattccgcc tttcgatggc ctgaacgatc tctgtatgaa tatcgatcgt
    89281 ctcgattttc agatgctgga tatcataatt tttattaaac aaagcaattg attcattaat
    89341 gattgggata atatgcagca aggctacgtt tccgctagct tctgcaatca tcgtatgaaa
    89401 atcgatgtct aattgaacat gttcttgtgt gccttctcga aaagaagttt caatcttttg
    89461 cgttaatttt ttcatttgga cgatttgatt cttcgttgca tattccgctg ccaaacctgc
    89521 catcttaggc tccaataaat atctcagttc aaataagtct cgtatcatcc gatcctgatc
    89581 ttcaatcaaa gaaaaaccga gtgggtcatt ggcaatccct cgcttatcac tgacaaatgt
    89641 ccccgctcct tgccgaactt caaggatatt cctggaagct agagcccgca cagcttctcg
    89701 caccgtgctt cgccccacct ctaaataatc ggacaattca tattcattcg gcagtttatc
    89761 tcctacttgc aactgcattt cctttaaata tctaaggatc ttgtcagtag ttacttctac
    89821 tagggtttta ttttcttcca aaccacatac ctccttttca tctgatgtat tttttcgtaa
    89881 ttattataac acgtttgaat catctgatga ttttttgtat acaaaattga ttaatccgtt
    89941 catagacata caaacgaaga agatatttac cataaaaaag actaggataa a
//
LOCUS       DAIGSZ010000003        87873 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.003, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000003 DAIGSZ010000000
VERSION     DAIGSZ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 87873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.003"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            150..1208
                     /locus_tag="NOB31_000189"
     CDS             150..1208
                     /locus_tag="NOB31_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HCI0972437.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1212..2246
                     /locus_tag="NOB31_000190"
     CDS             1212..2246
                     /locus_tag="NOB31_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HCI0972438.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(2348..3064)
                     /locus_tag="NOB31_000191"
     CDS             complement(2348..3064)
                     /locus_tag="NOB31_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI0972439.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3033..3818)
                     /locus_tag="NOB31_000192"
     CDS             complement(3033..3818)
                     /locus_tag="NOB31_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HCI0972440.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3809..4558)
                     /locus_tag="NOB31_000193"
     CDS             complement(3809..4558)
                     /locus_tag="NOB31_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCI0972441.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4856..5380
                     /locus_tag="NOB31_000194"
     CDS             4856..5380
                     /locus_tag="NOB31_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HCI0972442.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5396..6895
                     /locus_tag="NOB31_000195"
     CDS             5396..6895
                     /locus_tag="NOB31_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HCI0972443.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6983..7585)
                     /locus_tag="NOB31_000196"
     CDS             complement(6983..7585)
                     /locus_tag="NOB31_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0972444.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7689..8645
                     /locus_tag="NOB31_000197"
     CDS             7689..8645
                     /locus_tag="NOB31_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HCI0972445.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8950..9906)
                     /locus_tag="NOB31_000198"
     CDS             complement(8950..9906)
                     /locus_tag="NOB31_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0972446.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10080..10640
                     /locus_tag="NOB31_000199"
     CDS             10080..10640
                     /locus_tag="NOB31_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972447.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10633..11457
                     /locus_tag="NOB31_000200"
     CDS             10633..11457
                     /locus_tag="NOB31_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCI0972448.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11467..12084
                     /locus_tag="NOB31_000201"
     CDS             11467..12084
                     /locus_tag="NOB31_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI0972449.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12102..12785
                     /locus_tag="NOB31_000202"
     CDS             12102..12785
                     /locus_tag="NOB31_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCI0972450.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13468..14751
                     /locus_tag="NOB31_000203"
     CDS             13468..14751
                     /locus_tag="NOB31_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0972451.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14767..15654
                     /locus_tag="NOB31_000204"
     CDS             14767..15654
                     /locus_tag="NOB31_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0972452.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15671..16507
                     /locus_tag="NOB31_000205"
     CDS             15671..16507
                     /locus_tag="NOB31_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0972453.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16510..17133
                     /locus_tag="NOB31_000206"
     CDS             16510..17133
                     /locus_tag="NOB31_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972454.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17130..18422
                     /locus_tag="NOB31_000207"
     CDS             17130..18422
                     /locus_tag="NOB31_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0972455.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18781..18878
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18994..19575
                     /locus_tag="NOB31_000208"
     CDS             18994..19575
                     /locus_tag="NOB31_000208"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HCI0972456.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19578..20885
                     /locus_tag="NOB31_000209"
     CDS             19578..20885
                     /locus_tag="NOB31_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HCI0972457.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21301..21789
                     /gene="purE"
                     /locus_tag="NOB31_000210"
     CDS             21301..21789
                     /gene="purE"
                     /locus_tag="NOB31_000210"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HCI0972458.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21782..22906
                     /gene="purK"
                     /locus_tag="NOB31_000211"
     CDS             21782..22906
                     /gene="purK"
                     /locus_tag="NOB31_000211"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HCI0972459.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22919..24214
                     /gene="purB"
                     /locus_tag="NOB31_000212"
     CDS             22919..24214
                     /gene="purB"
                     /locus_tag="NOB31_000212"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HCI0972460.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24336..25724)
                     /gene="ltrA"
                     /locus_tag="NOB31_000213"
     CDS             complement(24336..25724)
                     /gene="ltrA"
                     /locus_tag="NOB31_000213"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI0972461.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(26293..26670)
                     /locus_tag="NOB31_000214"
     CDS             complement(26293..26670)
                     /locus_tag="NOB31_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972462.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            26926..27654
                     /locus_tag="NOB31_000215"
     CDS             26926..27654
                     /locus_tag="NOB31_000215"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HCI0972463.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            27654..27908
                     /gene="purS"
                     /locus_tag="NOB31_000216"
     CDS             27654..27908
                     /gene="purS"
                     /locus_tag="NOB31_000216"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HCI0972464.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            27910..28581
                     /gene="purQ"
                     /locus_tag="NOB31_000217"
     CDS             27910..28581
                     /gene="purQ"
                     /locus_tag="NOB31_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HCI0972465.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            28582..30804
                     /gene="purL"
                     /locus_tag="NOB31_000218"
     CDS             28582..30804
                     /gene="purL"
                     /locus_tag="NOB31_000218"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HCI0972466.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            30789..32228
                     /locus_tag="NOB31_000219"
     CDS             30789..32228
                     /locus_tag="NOB31_000219"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HCI0972467.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            32251..33303
                     /locus_tag="NOB31_000220"
     CDS             32251..33303
                     /locus_tag="NOB31_000220"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HCI0972468.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            33300..33878
                     /gene="purN"
                     /locus_tag="NOB31_000221"
     CDS             33300..33878
                     /gene="purN"
                     /locus_tag="NOB31_000221"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HCI0972469.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            33875..35410
                     /gene="purH"
                     /locus_tag="NOB31_000222"
     CDS             33875..35410
                     /gene="purH"
                     /locus_tag="NOB31_000222"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HCI0972470.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            35426..36700
                     /gene="purD"
                     /locus_tag="NOB31_000223"
     CDS             35426..36700
                     /gene="purD"
                     /locus_tag="NOB31_000223"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HCI0972471.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            36822..37736
                     /locus_tag="NOB31_000224"
     CDS             36822..37736
                     /locus_tag="NOB31_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI0972472.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(37869..39434)
                     /locus_tag="NOB31_000225"
     CDS             complement(37869..39434)
                     /locus_tag="NOB31_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI0972473.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(39427..40878)
                     /locus_tag="NOB31_000226"
     CDS             complement(39427..40878)
                     /locus_tag="NOB31_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0972474.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(40892..41908)
                     /locus_tag="NOB31_000227"
     CDS             complement(40892..41908)
                     /locus_tag="NOB31_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0972475.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            42128..43216
                     /locus_tag="NOB31_000228"
     CDS             42128..43216
                     /locus_tag="NOB31_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HCI0972476.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            43270..44796
                     /locus_tag="NOB31_000229"
     CDS             43270..44796
                     /locus_tag="NOB31_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HCI0972477.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            44798..46003
                     /locus_tag="NOB31_000230"
     CDS             44798..46003
                     /locus_tag="NOB31_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0972478.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            46260..47237
                     /gene="guaC"
                     /locus_tag="NOB31_000231"
     CDS             46260..47237
                     /gene="guaC"
                     /locus_tag="NOB31_000231"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HCI0972479.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            47501..48925
                     /locus_tag="NOB31_000232"
     CDS             47501..48925
                     /locus_tag="NOB31_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCI0972480.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            49386..50495
                     /gene="pdhA"
                     /locus_tag="NOB31_000233"
     CDS             49386..50495
                     /gene="pdhA"
                     /locus_tag="NOB31_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HCI0972481.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            50498..51475
                     /locus_tag="NOB31_000234"
     CDS             50498..51475
                     /locus_tag="NOB31_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HCI0972482.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            51500..53143
                     /locus_tag="NOB31_000235"
     CDS             51500..53143
                     /locus_tag="NOB31_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HCI0972483.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            53151..54557
                     /gene="lpdA"
                     /locus_tag="NOB31_000236"
     CDS             53151..54557
                     /gene="lpdA"
                     /locus_tag="NOB31_000236"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HCI0972484.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            54719..54994
                     /locus_tag="NOB31_000237"
     CDS             54719..54994
                     /locus_tag="NOB31_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HCI0972485.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            55000..55767
                     /locus_tag="NOB31_000238"
     CDS             55000..55767
                     /locus_tag="NOB31_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HCI0972486.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            55935..57764
                     /gene="typA"
                     /locus_tag="NOB31_000239"
     CDS             55935..57764
                     /gene="typA"
                     /locus_tag="NOB31_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HCI0972487.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            58025..59797
                     /gene="recQ"
                     /locus_tag="NOB31_000240"
     CDS             58025..59797
                     /gene="recQ"
                     /locus_tag="NOB31_000240"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HCI0972488.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            59911..60213
                     /locus_tag="NOB31_000241"
     CDS             59911..60213
                     /locus_tag="NOB31_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HCI0972489.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            60216..61379
                     /locus_tag="NOB31_000242"
     CDS             60216..61379
                     /locus_tag="NOB31_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCI0972490.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            61405..64833
                     /locus_tag="NOB31_000243"
     CDS             61405..64833
                     /locus_tag="NOB31_000243"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HCI0972491.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            64854..65978
                     /locus_tag="NOB31_000244"
     CDS             64854..65978
                     /locus_tag="NOB31_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972492.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            65968..66405
                     /locus_tag="NOB31_000245"
     CDS             65968..66405
                     /locus_tag="NOB31_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI0972493.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            66389..66727
                     /locus_tag="NOB31_000246"
     CDS             66389..66727
                     /locus_tag="NOB31_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HCI0972494.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            66846..67406
                     /gene="rsmD"
                     /locus_tag="NOB31_000247"
     CDS             66846..67406
                     /gene="rsmD"
                     /locus_tag="NOB31_000247"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HCI0972495.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            67403..67894
                     /gene="coaD"
                     /locus_tag="NOB31_000248"
     CDS             67403..67894
                     /gene="coaD"
                     /locus_tag="NOB31_000248"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HCI0972496.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            67884..68927
                     /locus_tag="NOB31_000249"
     CDS             67884..68927
                     /locus_tag="NOB31_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HCI0972497.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            69086..69814
                     /locus_tag="NOB31_000250"
     CDS             69086..69814
                     /locus_tag="NOB31_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HCI0972498.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            69930..70175
                     /locus_tag="NOB31_000251"
     CDS             69930..70175
                     /locus_tag="NOB31_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI0972499.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            70172..70390
                     /locus_tag="NOB31_000252"
     CDS             70172..70390
                     /locus_tag="NOB31_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HCI0972500.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            70526..71065
                     /locus_tag="NOB31_000253"
     CDS             70526..71065
                     /locus_tag="NOB31_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HCI0972501.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            71058..73331
                     /locus_tag="NOB31_000254"
     CDS             71058..73331
                     /locus_tag="NOB31_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HCI0972502.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            73369..74415
                     /gene="holA"
                     /locus_tag="NOB31_000255"
     CDS             73369..74415
                     /gene="holA"
                     /locus_tag="NOB31_000255"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HCI0972503.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(74504..74758)
                     /locus_tag="NOB31_000256"
     CDS             complement(74504..74758)
                     /locus_tag="NOB31_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HCI0972504.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(75158..75427)
                     /locus_tag="NOB31_000257"
     CDS             complement(75158..75427)
                     /locus_tag="NOB31_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972505.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(75897..76352)
                     /locus_tag="NOB31_000258"
     CDS             complement(75897..76352)
                     /locus_tag="NOB31_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HCI0972506.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(76490..78418)
                     /locus_tag="NOB31_000259"
     CDS             complement(76490..78418)
                     /locus_tag="NOB31_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI0972507.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(78615..79448)
                     /locus_tag="NOB31_000260"
     CDS             complement(78615..79448)
                     /locus_tag="NOB31_000260"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCI0972508.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(79640..80344)
                     /locus_tag="NOB31_000261"
     CDS             complement(79640..80344)
                     /locus_tag="NOB31_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI0972509.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(80367..80993)
                     /locus_tag="NOB31_000262"
     CDS             complement(80367..80993)
                     /locus_tag="NOB31_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI0972510.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            81319..83694
                     /locus_tag="NOB31_000263"
     CDS             81319..83694
                     /locus_tag="NOB31_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HCI0972511.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(83718..84209)
                     /locus_tag="NOB31_000264"
     CDS             complement(83718..84209)
                     /locus_tag="NOB31_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HCI0972512.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            84396..85316
                     /locus_tag="NOB31_000265"
     CDS             84396..85316
                     /locus_tag="NOB31_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0972513.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            85470..85814
                     /locus_tag="NOB31_000266"
     CDS             85470..85814
                     /locus_tag="NOB31_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HCI0972514.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(86004..86504)
                     /locus_tag="NOB31_000267"
     CDS             complement(86004..86504)
                     /locus_tag="NOB31_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0972515.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            87032..87115
                     /locus_tag="NOB31_000268"
     tRNA            87032..87115
                     /locus_tag="NOB31_000268"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:87066..87068,aa:Leu,seq:cag)
     gene            complement(87439..>87873)
                     /locus_tag="NOB31_000269"
     CDS             complement(87439..>87873)
                     /locus_tag="NOB31_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HCI0972516.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        28295 a        15344 c        18795 g        25439 t
ORIGIN      
        1 aatcacttta cataagtttc aaaagtttct ttaatttcct attgttcaat aagtaacaat
       61 gtaaagataa aattaaaaat gttaatacgt attagcaaaa taaaagcttt ttttattgtg
      121 aataaatgaa cataattagg aggagaaaga tgaacttatt tgacattttt cgatcgactt
      181 tgacagatat gtcgattgtc agtgcaatca cttcaacagt ttttattata ttattagggt
      241 ttgtttgtag aaaaaagggg attttttctg aatctgttgg aaaaattcta tcgaaagtcg
      301 tcttaacagt ggctttgcca gcactggcat ttcgagcttt catgcaagat atcaatacag
      361 aattactgat gcaaggaatc aatgtcttga tttggggatt agttatttat attattctta
      421 ttctagtttc aaaacctttt ttcttaagct ataaagggga taagcaaaca acgttgcgtg
      481 tcctgacgat ctttggttct acgacctttt tcggaacgcc tatcgtcagt gcgatttatg
      541 gtcctgtcgg cgtgatgtat tcctcaattt tcaatattgg ctaccgaatc tttttgtatt
      601 cttatggata cataaaaatg agtggcttga agatggaagc taaaaatatc aaagcgatgt
      661 tcgtcaatcc aatcattatc gctacttttg ccggcctttt catttggctg ttccaagggt
      721 atctgccaca agtgtcagtt acaggtgcag aaggagagat aagccaagta gcgtttttgc
      781 gaattgacca gactgcaccg tggctatttc agccgatgga ttatttagct ggtttaagtt
      841 caccattggc gtggctagca atcggcgcaa cattaggtga agtaagcttc aaaaaagctg
      901 catctgaaaa aacttcatgg tattacagtc tagtcaaagt ggtatttgta cctgcattga
      961 atatcgtgat tctagcagtt ttgacggcaa cgaatattct accagtcaat tttgaagcac
     1021 tggcaacaat cgttatcatg atggctacac cagctgcaac agtggcagca gcctatgcta
     1081 tcagttttga tagggaggca cttttagcct ccaatgcatc cttactgtca actatttttg
     1141 ctgtggtact gacacctgta tggatcgttg tattacaaat gattcatggc ataggtttat
     1201 tttcataaga aatggaggaa gaaagtatga gaatcgcatg ttacggtgtt cgtccgaacg
     1261 agatagattt ttttgaaaaa ttgaatattt accattatga tctcagtctt tatgaagaac
     1321 tgttgacaca tgacaatatc gtgtcagcaa aggaccatga tgctgtattg ttgaggggaa
     1381 attgtatagc agatgagacc aatcttgcaa aaatgcagga atatgggatt cgttatgttt
     1441 ttacacggac tgtgggagtc aatcatatcg atctacaagc ggcagctgat tttggtatga
     1501 cagtagcccg tgtaccatcg tattcgccaa atgcgatagc agagttatct ttgacttttg
     1561 ccatgatgct tttgagaaat actgcgtata cgacgatccg aacatctttc aaagattttc
     1621 gagtggatga gcaaatgttt agtcgtgaaa tcagaaattg cacagtaggg atcataggaa
     1681 caggcaggat agggttgacg gaagctgttt tgtttaaggg actaggagcc aaagtgatcg
     1741 gctacgatat tcatcagaca gaagctgcta aaaaagtatt gacgttccac tcgcttgaag
     1801 agttattagc caaaagcgat attgtcagta ttcatgtacc tcatatccca ggtgaaaacg
     1861 atcaaatgat caatgaagga tttttagctc aaatgaaaaa aggtagcatc ttgattaata
     1921 cagcccgtgg agagcttcaa gataatgaag ctattttaag agctttgaaa agcaatcatt
     1981 tagctggttt tgcaaccgat gtttttgcaa atgaaacaga ggtttttttc cgatccttca
     2041 agccatggga gacgattcca gaccctgcta tccagcaatt agtagaaatg taccctagag
     2101 ttcttgtaac cccgcatgta ggttcaaata cagatgaggc attatcaaat atgatttcga
     2161 caagtttcga gaactttcgt gaaataatag aaactggaaa aacgaaaaat gaggtatctc
     2221 ttcctaaagc ccgtcaatta agataagaaa acatggatat tcgtcaataa aatgtttaaa
     2281 aatagtccaa gtaaacagtt gttacttctg tatacttgga ctattttgta tgggataatt
     2341 cgatgactca acagtaatct gtgagctttt tccgcccatt ctttgtcaat tcataacagg
     2401 ttagcggccg gccgatttcc aaatatttga ttctttcgtt caatatatct tgttctacta
     2461 aaaaattcaa atatttcttg acggatatac gtgacagtga gcttttttga gccagttctt
     2521 ttgttgaaaa aatagtatct tcttttagaa taaatgcact tatttttttt aaagtcagtt
     2581 ttgacagacc tttaggcaaa tcgatgaatg atggtatttc gtgaatggga gtggtgtggt
     2641 tgaatacttg atcgatcaat ttctgatcgg ctttttcagt cgtttggatt gtctgagaga
     2701 aagcaagata cttttcgatc gccagctgaa aacgttgcaa agtgaacggt ttgatcaaat
     2761 aatctaaggc accgtagcgg atcacattct ttatggtttc gatatcatct gcagcagtga
     2821 tcaaaatcac tgggatatca tttccttgct gtctaagcca agataaaaaa tggataccac
     2881 tttcgccagg catgtataca tcaagcagca gcagatctgc gtttttttgt ctgaaatatt
     2941 tttttccttc ttctacattt ctgaaacttt cgattacgtt catattaggg atgctttcca
     3001 caaaagtacg attcaattct gcaaccattg gatcatcttc gattatcagg acatttgtca
     3061 tcattttgat cttccttttt tggtaattct agatagacga ttgtaccgcc atttgtttgt
     3121 ttggaaaatt ctaaaaatcc accgtggcgt ttgacgattg aatggatgag attcaatcca
     3181 aacccacgat tgattccctt cgtcgaaaaa cctagcgtaa atattttttc tgagatttct
     3241 tctgatatcc cgacaccgtc atcgcagacg gtcacgatga atacttcagc ttctgtgtca
     3301 tagtttaaat gaatccggac ctgtccgttt ctttcatgtt tttgtagcac ggcttctttt
     3361 gcattatcaa gtaagttccc taacacttgc aaaagtgaat ggatggagtc atccatctcc
     3421 attttaggga taaaagaatc gctttctaac agcatttcaa cagattgttc tttggcttcg
     3481 tttattttgc ctaataaaaa accggcaatt gcaggtactt tgatcagact tgagacttgg
     3541 ccaatctctt ttttataatt ttgatttagc tgctggataa aatgggtgac ttcttcatac
     3601 ttcttcaaat caatcaaacc agaaatgaca tgaagtttat tcatgaattc atgggtttga
     3661 gctctcatgg agtttatata ttgtttcgtc cccccaagct cctccattaa tttcattact
     3721 tctgatcgat ttcgtaaagt tgcgactgct cctaaaaaac ggtcattgct aaaaagaggt
     3781 gtaacgctag aaatagtttc tatcccattt aaatacatgg attgagtccg aacggtcgtt
     3841 tgatgctcaa tcgtctcttt aaacaaaacg tcatatagat tatcactgat ttttttccta
     3901 cttcgaaatc caatagctgc tctgtttggt agaaaatgtt ttttgcaggt gtattgatca
     3961 agaggatagt tttatcagaa gagatggcta agattccttc atctacttca ttttcgataa
     4021 tcgttttttc acttaactgt tctgctattt cttgtggttc aagtccaagc agtacttttt
     4081 tcattttttg ggcaagaaaa acggcgccta tgatgcctac gctaagtcca ataatcaatg
     4141 aaaaaacaat cattttttgt ccatctttga cttgattgtc aatcgtgttg tttgttaagc
     4201 caacacaaac tgcaccaata atctcttgat cataataaat agggacgaaa tagcggaagc
     4261 cgaaccctaa cattccttct ttttcagaga aaaattcttg tcctccaatc acttttttca
     4321 catcttcatg acttgagaaa ggaagaccga tgtaacttgg gtctgcgtga gaatatcgaa
     4381 tgccttcagg gtccatgaca acgataaaat ctaaattcga tgcaatcatg atttcatttg
     4441 ttattccttg aatcgcatgt gtcgggtcac cagtctgcag ctttttttgg atgagtttat
     4501 cattggcaac gattttagca atgctagaga ttttatctga cacactagat cggttcatcg
     4561 aaagaataaa attcctgatc aatatggcag aaacaatcaa agaaacgaat gtggagaaac
     4621 aaacgacaag gatgatcgtg ttctggagct ttaatggttt tttcttaaaa aaaggaaaca
     4681 taggctacct cgaaagaatt tattgtgaaa attttaacat gaaaacaaaa atttaacaaa
     4741 ttgtcaacga taaacacaac cttcctataa aaaacaccac tgagtcggta aaagaagcta
     4801 tacagaattt tcaaacattg gtatgataga cgtagaaatg gaaggaggcg tgtatatgat
     4861 agggggaatc gcacttgaga cgatttattg gtatacattg ctgatttgtg caggattggc
     4921 agtcctattg attatttttg gagatgtatt cgattttgat ggcccgcttg atccgatgct
     4981 tattatccct tggttaactt tcacaagctt atttggtttt ctaggtgagc gtttaacaga
     5041 tcaatcatct ttatttttat ttattgctag tggaggcata tcgatagtgt tggtattttt
     5101 gcttaatttc tatatattga tgccgatgaa acatgccgaa tcaacgatgt cgtcttctga
     5161 aaaaactctg gaaggacaag tagctgttgt gatcacaccg atccctgtac gaggtatggg
     5221 agaaattcag ttgaaaagtg ttaccggttc cattagtcgt ccagcttgtt tttacagccc
     5281 ccaagaacag acagctgagc ggggaacgaa agtattgatc attgagatca aggaaagaat
     5341 ctgttatgtc atgccttatg aaagcatgat aaaagcttaa aggagcgtgt gttaaatgga
     5401 aataccagtt gtttttatcg cgatcgcaat cgcagctttg attttactga tgttgctgat
     5461 cgtctttgta gcgaagtacc agacagcaaa accggatgaa gcgttgatca tcagtggaag
     5521 ttatttagga agcaaaaatg tgcacattga tgaaagcaat aacaaaatca aaattgtgcg
     5581 tggaggtggc gcattcgtct tgccagtttt tcaacgttcg aatcggatca gtctattatc
     5641 gagtaaattg gacgtctcca cccctgaagt gtatacggaa caaggcgtac cggtgatgtg
     5701 tgatggtact tcgatcatca aaatcggttc atctgtagaa gagattgcta cagcagcaga
     5761 acagttttta ggcaagacaa gagaagaact ggaaaatgaa gcaagagaag tattagaagg
     5821 acacttgcgc tcgattcttg gttctatgac tgtagaagaa atctatcaaa atcgcgataa
     5881 gttcagtcaa agcgtacaag aagtcgcttc tgtagacctt gcaaaaatgg ggttgatcat
     5941 cgtttctttc actatcaaag aggtcagaga caaaaacggt tatcttgact ctttagggaa
     6001 accaagaatc gcccaagtca aaagagatgc agatatagca gaagcggaag ctctaaaaga
     6061 aacgcgtatc aaaaaagctc aagcagaaaa agaatcacaa gcagctgaat tacagcgaca
     6121 aacagagatc gcagaatcat taaaagaaaa agaactgaaa ttagcaacct acaaacaaga
     6181 acaagatgtt gctaaagcaa aagcagacca agcctacaat ttagaaagtg cccgagcaca
     6241 acaacaagta atcgaacagg aaatgcagat taaaatcgta gaacgtcaaa aacaaatcga
     6301 actggaagaa aaagaaatca cacgtcgtga aaagcaatat gattcggaag tgaagaaaaa
     6361 agcagatgcc gatcggtacg ctaaagaaca agaagcacaa gctcaaaaag tcaaagaagt
     6421 gactgaagcc gaagcagaac gattccgtgt ggaagcactg gcagaagcgg aagccaataa
     6481 gacacgttta gctggacaag cagaagccga agcagcacta gcaaaaggaa aagcagaagc
     6541 cgaagcaaaa caaaagatcg ccaatgcctt caaggaatat ggcgaagcag ctgtcttgag
     6601 tatggttatc gatatgctac cgcaattgat gcgcgaagca gcacagccgc taggaaatat
     6661 cgaaaaaatc tctgttgtcg atacaggaag cagttcagga gaaaccagtg gagcgaaccg
     6721 agtgacaaat tatgccacaa atttgctttc ttctactcaa gaaacactaa aagcgacaac
     6781 aggacttgac ttgaaggaaa tcgtagagaa tttgtcgaca cgtgggacta ctagccaagt
     6841 aaatatgtat gaagcgccaa aagaggcaga acaaaactcg atgaaggaag aataaagtag
     6901 tacacttcac cgttcaatca aaaatggagg aagacttttt aaagttcttc tctccatttt
     6961 tttattttat tgcaaaagaa aattagtcct cgctattttt cttttgtttt tggatcttag
     7021 cttctatctc ttgtaaattt gttcttagca atcgttcttt cttttggagt tcgaccaaat
     7081 cttctgatag ttcttccttc ttttctgttt caggaggacg aagaaagaaa ttgataccga
     7141 ttgcaatgaa tgtccctata aaagtatcta gtacacgttg gatagcatac aaagcggatt
     7201 cgccttgagg gatgctcaac gcaatcagca acaacgtagc tattgcggaa atgataccgg
     7261 aattattgtt aataccatct gacacgacga tcacaataat aactagaata ggaagcaaga
     7321 tcaattctac caaaaaatca ttgtgaaaat agcttttgac aaaaaaataa atgatagcta
     7381 atgtaccacc taatgtattg ccgatgatcc tagactttcc aaaagaaacg gttgtagtca
     7441 agtcctgacg caaagaaaaa acagcagata atgcagcaat catcgggatt cctcgttgag
     7501 tcaaatgaaa aaacaagata cataaaaaaa cagctaaggc acttttgatc gtacgcatac
     7561 ctagtcgaaa acggccaaat tgcatagaga ttctcctttt tggtcttttt actatcatac
     7621 ctaaactttt gtctgatagc tagtttttca ttattcaagt ataattaaaa taaaaaaggg
     7681 ggaagtaaat gcgtatagga atgcgaacag tcaaaacagt gatcagtgtc ttcttttcga
     7741 tggtcacagc gggtagctta tcgctgttgt attggccagc tgcagggatc attgcattat
     7801 taagtgtagg aaataccaag cgctctacat tgcgtacggg catgaatcga atcgcagcct
     7861 ttatattagc tacggcaaca gcactgttca gtttttttgc tgttgggtat actatttttg
     7921 gcttcagtct ttttttattc ctgttcatcc cgcttgcctc tcgcttcaaa ttaaccgaag
     7981 ggatagtagt aaattcggtt ttggtcactc attatttagt ggaggaaaac atgtcttggc
     8041 agctgatcgg caatgaagcg ggattaatgg cgattggatt agtatttgct ttgcttgcaa
     8101 atgtttacat gccagatcgt acgaagcagc tgaaggaaaa ccaaatacag atcgaaaaag
     8161 aatttcgaaa tattttgaga caaatggcag aatttctttt atcagaaaat aaagaagatg
     8221 tgcagatcaa atgcgaacat ttactgacat tcattcgcga aagccaagaa gatgccagag
     8281 aacatcaaga aaactactgg ctcagacagc cgctatacta cgaaacttac ttctctatga
     8341 gaagagcaca ggccaatgtg attaaagaca tgctggaaaa tctagagaga atccagcaac
     8401 cagcttatta tggaaaacat atctatggtt tattgattta tactgcagaa acattttcag
     8461 agtcaaatga tggcagacaa attttaacac gtattgaaga agtttatgta ttgtatcggc
     8521 aaatgcctct gccgactagt cgccctgaat tcgaggatcg agcagaattg ttccagtttt
     8581 tgcagtcttt taaaagtttt attgaaatca aggcagaatt ctcccaacaa aaaatccaaa
     8641 aatagaggtt gtgaattcag ctaatattca ggtcaaaaag ctgatttcac aacctcttct
     8701 ttaaacggtg ttctcctgtc aactcctcgg tcacaagtca caatattcaa caaacatgag
     8761 aagctgtttt ttgaaattgc tccttgtgac tcggagctga acggtaggct cacaacctct
     8821 ttcttaaacg gtgttcaaaa gctttcctct gcggtaataa gtccagccaa acgaaaaata
     8881 ggaggagcta tttttgtttg gctgttctta ttacttgatg cagaacagct ttttcacaac
     8941 cttttaaaat tacatatttt tccatagaac ttgcatttga tccaagattt cgatgacatc
     9001 ttttgtcaag aagagagagc gattgggcaa gtcaccttca atcatgtgta ccatattctt
     9061 tatttcgtaa ttcattgctt cagatgtatt cccgctttcg atgaattcct ttgtaccatc
     9121 tgtaaataag atctccgcac gatcagcacg cgggtaatca gcaatcgtca cataaccgtt
     9181 ctcaaaggca acgataccga cttttggcat ttttgcctga aaagtcaagc tgacagcagc
     9241 aagttcattt tctttgttac gcaagatagt gacggattgt tcgtccacgc ctgtttcaaa
     9301 aggaaccatt gtagaggcaa ctacttcagg ttgagagctc aaaaagaaac gagcgaaaga
     9361 tacagcatac gtaccgatat ccaacagagc tcctccagct aattctggat tgaagaaccg
     9421 gtttttaggg tctggttctt tgtaactgcc gaaaggtgct tggatcattt ttaaagcccc
     9481 cagttttcct gtatccatta ttgagcgtaa ctgctgataa agtggcatgt tgaagattgt
     9541 catcgcttct gctaagatca aattcttttc ttctgctaag cgcatagcgt cagccagttc
     9601 ttttttattc atcgtgatgg ctttttcaca tagaacgtgt ttgcctgctt ccaatgctgc
     9661 caagatatgg tcgatatgct gtctatttgg tacagcaatg tacacgatgt cgatttcagc
     9721 atcgtctaac atttcttgat agcttccgta agcttttgga atattgtaac ggtgagcgaa
     9781 gttttccgct ttttctgaag ttctggaagc aactgctgtt agttcgctcg tctcttgatt
     9841 gaagctttcg gcaaactcat gtgcgatggt accaagacca acgattcccc attgatattt
     9901 tttcatctga aaacgctcct tcatagttgg attgagtttc ttgtctgtct attattataa
     9961 caaaaatcac gaagaataaa gaggagagga cttgaaacat taaaaaaaat gaaagcagcg
    10021 atttaagagg tgctttttga tcaaaactta agtagaatag ttaaaaggag gggataaacg
    10081 tgcatcaagt atatattgat cttattatga gtgtattatt agaacagttt gaaactgaaa
    10141 aaaatttttt agatgaatac ttgctgatca gtccagaaca atggcaaaaa tggaaagatg
    10201 gcgagaaaaa tctgccatct gaagcgatgc agaaagtaaa aaatcttttc actgattatg
    10261 aatggatgct aacgcaaaag attttgcgtc aaacgattat ttttcccgaa aaacgaaacg
    10321 ttgccgttgc agagtacaag caaatcaaaa cacgcatcgc gcaaaaatgg cttagcagca
    10381 aagcagcaaa agtcgagctg atccctttga aaaataatca gcaggctggt agataccttg
    10441 acttgaaagt aagtattcaa tatgatgaat ggggctatga tgatattttg aattttcgtc
    10501 tgccagcaga tgttcaaaaa cagatcgaag gagaaaaaat cgaacttctc gattgggtga
    10561 atgaaaatct ggaagaaact tacgttcatg aggcgaatgg ggaacgtgaa gaacaacgaa
    10621 aggatttttc aagtgaataa atttttagga tttggagcag ttgtgattat gatcgcagca
    10681 atgggctatg ttatttttag cgatgatgat tcgcatgttc aagccggcaa tcaagcagtc
    10741 gaacgaacaa gcaccaaaac aactgctagt aaagaaaaga acagtcaaac aaccagcagc
    10801 aaggtaaagg acaaagaaac aaaagatcgt acgtccaaac aattgccaga tgttaaaaca
    10861 gacgattgga agctagtttt ggttggtcca gatcacaaat tagaaaaaga aattgatgag
    10921 tctactcaat tggcatcatt aagtaacgga tacttgatcg acaaacgcat tgctccagaa
    10981 tatgaagcat ttgccaaggc tgctgaagca gctggatttc cattagtgat ggtctcagct
    11041 taccggtctg tatcatccca acaacaagtt ttcgaacaaa atgtccaaga tgtgatgagt
    11101 cgtcaaggtg tatcagaaga ggaggcgaca aagattacta aagaaacgat tacggagcca
    11161 ggatacagcg aacaccacac aggtctggca gtcgatgtcg tcgatcaaaa ctggtacaac
    11221 agttatcctt ctactgtatt ggatgcaagt tacggagatc agcctggagc taaatggatc
    11281 gcagataatg ctgcgcagta tggatttatc gttcgttatc caaaaggaca cgaagatata
    11341 actaagatca catatgaacc ttggcactta cgttatgtcg gtaaagaaaa cgctgagtat
    11401 atcaccaaac accaattgac gctagaagaa tatctgaatg aattaaatga aaagtaggaa
    11461 ttgatcatgg cgaaaaaaaa gtggaaaaag caaaagcgca agaatatccg ttggccagca
    11521 gtggttgccg gtgtagcagt gatactctta gcctttgttt tttccttgaa gaatctgtct
    11581 tctcctttta ctgataatca gcaagaaaat gaagcgcaat cccatcagca atttattgaa
    11641 cggcttgttc cgcatgccca agaactacaa gatggttatg gagtgcttcc tagtatcatt
    11701 ttaggacaag ctatattaga atcaaattgg ggaaaaagta ccttggctag caaatacaat
    11761 aatcttttcg ggatcaaggc ttatggggat cagaagaaag taagcctgga aacaaaggaa
    11821 tttgttaacg aagaatggat aactatccaa ggagacttca aagtgtatga ttcatgggaa
    11881 cagtccatgg atgaccatac acaactgttc gtccaaggag tagattggaa tcctgcgctg
    11941 tatgaaaaag tgattacggc caccaactat caggaagccg cacaagcatt gcaagatgca
    12001 ggttatgcga cagaccccgg ttatgcgcaa aaaatcatcc aggtcatcga gacgtatcaa
    12061 ttgaatcagt atgaccggag atagcaaagg agaagtggct gatggcagaa caatttacgc
    12121 cagaaatcat gacggaattg agaaaagata tcgtaagagt accggaaatc attttagaag
    12181 caagcgggat caagatattt ggaaaattga tccgttcgat catctttact acggatattg
    12241 cgatcatacg taatacaaat gcgaatgcag taattgctgt gtatcctttt acacctcatc
    12301 cagcgattac taaaagcatt attgaggcag ctgacattcc agttttctcc ggtgtaggtg
    12361 gtggtttgac acaaggtgct cgttcttcct acatgagcat gttcgcagaa gcgcaaggtt
    12421 cgttaggggt cgttttgaac ggtcctacgc ctttagagac agtaaaagaa gtttgtcgag
    12481 tagttgatat tccagttatc agtacggtaa cgtcgaaata tacagaaata gatgaaaagt
    12541 tagcagctgg tatttcgatt atcaatatca gtgcaggtaa agaaactgca gaagcagtac
    12601 gccattttcg taaaaaatat cctgaacttc ctatcattgc gacaggtggt ccaacggaag
    12661 aaagtattgc tgagaccatt caagcaggag caaatgccat cacatatacg ccaccaagta
    12721 gcggagagct ttttagtcgt aaaatggaaa aatatcggga aactgagaaa aagaatcatg
    12781 aataacaggt gagaatcaaa agacgaggaa gagcagatag tggctcttcc tcgtcttttg
    12841 tactccagta ctatttgttc agaattcaaa aaaaagagaa atttttttgt ttttttacct
    12901 gtaatgtaca taagaagagt taaaaccttt tgttattatt agcattctaa caaaaaaatg
    12961 tcttgattta ttgaagcgct ttctatagaa tgaaaaacga ataaaaacta aaaaaggcac
    13021 ccgacaattt agtagcagct aaattgtcgg ggcttgaaaa gtcagcggga actgaccaat
    13081 caagttgcca tagtcaatgc ttgtgcatcg acgtgtatat tgtacctaat ttcatacaga
    13141 attactagtt atttttctgt tttttaggga agagcgcaca cgaagaagca tgcttattta
    13201 gctatgtcaa ggatattggg cagttgtctg atatcctttt ttctttgcgt aattatcctc
    13261 ccatcattga agcaagaagt gtttttagcg atgaaagaag aatcagcact atctaatttt
    13321 tcttgaaagt attgagttgt tcatcctagg cagaacgata aggcaagtct tggtttttat
    13381 tccccttgaa aaagatcgtt taataaatat gttctgtata aaaatacagt atattgaaaa
    13441 ataacaatgg aagtagaggt gcagagaatg aagaaaagaa tgagaatcat cttagcttta
    13501 agtgttatgt tattcttctt gacggcttgt gggcaagaag atgacaaaaa aatcacgctg
    13561 aacatggctt ggtggggttc gcaagtccga cacgatgcaa cagtaaaagt aatcgagctt
    13621 tatgaagaaa aaaatcccca tgtgacgatc gattatgaat tttatgatta tgaaggatat
    13681 tacacaaaat taggtacact agcagcatca gatgatatct gggacatttt ccaactgaac
    13741 aatcaatttc ctcaatacat caatcagatt gaaccattag atgaatatgt ggagcaaggg
    13801 ataattgata tttctaatgc agatgaatcc tatttagcaa cgacgactta cgacgggcaa
    13861 ttagttggac tgtctaacgg ggtgaattcg tttgcgattg cttacaataa aaatatattt
    13921 gaacaattaa atatccctga accagcttca aattggacat gggatgaatt tgaacaaatc
    13981 agctatcaaa tcactgaaga attaggaatc tatgctattt caagattcga agattttata
    14041 gctggctgta ttattcaaat accacaagtt gagaaaggat tgaattttta taatcgggaa
    14101 gatctatcta acagcttggg atttgaaaat ccagactatc taacagattt tttccagctg
    14161 cgtaaaaatc tggtagacaa aggggcccat ccagaaccag gtggtggagc tgcaagtacg
    14221 acggatctgt cttttcaggc ggttagggat agagaagcgg caatggtgtt tctatcaagt
    14281 aaccagttga cagaaatatt gtcaggggct cctgaagata tggagattca gttgattaat
    14341 ccacctcgca gaaaagcaga tggagaatct ggtatccctt tacgttcttc gcaaatgctg
    14401 agtatggcaa aaagctcagc ccataaagaa gaagctgcta agtttattga tttctttcaa
    14461 aacagtgaag aagccaatga aattttaaaa ggagaacgtg gtgtaccaat catgtcgaat
    14521 attcgagaac agctcgctcg tgcagatgat gcaactttgc aagcgacatt tgattattta
    14581 gaaatgattt ccgatatgga caacggcgaa gtgaatgtct ttgatagtgc tttgaatccg
    14641 gaaattcaag accaatacaa tcttttagtt gaaaaagtca tttatgaaga agtaacagca
    14701 gaagaagcag cagagagtct ttatgagttt gcgtcaaaca ttctaggata gcagcaggag
    14761 gaaggcatga aaaaagaaaa actaaaacgg ttcttggatc aagacaatgt ggtcggttac
    14821 gtatttgctt ctccattcat cctaggattt ctattgataa cagtgatacc gatgatcttg
    14881 tcactttatt attcgttcac cgattatcgt ttgggaaatc cagtctcatg gatcggcttg
    14941 gataattata taaagatgct gagtgatgcc cgttttttga actccatccg agtcactttt
    15001 ctctatgtat ttgcatctgt acctgtgaaa ctgatctttg gtctattgat tgcttatctt
    15061 ttaacgagga atatcaaagg aacgactttc tttcgttctt tgtattatgt gcctagtttg
    15121 atcggtggca gtatttctat cgctctagtt tggcgggagt tgttttctaa aaacgggtta
    15181 gtgaatattt tcctggaacg attaggcgca cctgcgcttt cctggtttag cgatcaaaaa
    15241 ctggtcatga tccctcttgt tttgatgtct gcttggcaat tcggttcggc aatgatcatc
    15301 tttgctgcag gtatcaaaga gatcccaggc tcgtattatg aagcggcaga gatcgatgga
    15361 gcgaacaaat ggcagacgtt ttacaagatc acgttacctc ttctttcgcc gatcattttg
    15421 tataacttgg ttatgcagac aatcgcggcg tttatgactt ttacgcaggc atttatcatt
    15481 acccaaggtg gtccgaatga tgccacgaac ttttatgctc tttatgtgta taaccaagct
    15541 ttttctttta attctatggg gtatgctagt gctatttcgt ggatcatgct gttgattatg
    15601 ggagctgtca cctttctgat tttcaaatca tcaaaaaaat gggtcgttgt gtgaatgaga
    15661 ggaggaagaa atgaataata cagtaacgaa atggtttcaa tacggtttta ttttgctatt
    15721 aggtctagtc atgatttatc cggtcttatg gatgatcgca ggttctttta aaacggatca
    15781 agagattatg agtggttcgc tgaatttgat tccagagact tttcaatggg aaaattacgc
    15841 aaaaggatgg gcggggtttg ctggaatttc attttttact ttctttagga attcgtttgt
    15901 catctctgca gtttcgacga tagggacagt tctgagctcg acttgtattg cttacgcatt
    15961 atcgagaatc gatttcaaag gaaaaagatt ctggttcgtc gtcatgttag taacgatgat
    16021 gattcctgca caagtgattt tgattccgca gtttattatt tacaatcggc tgaatttggt
    16081 tgggacgtat gtgccgctga ttttaccaca tttttttgga caagcatttt tcatttacca
    16141 gatcatgcaa ttcatggtca gcatccccaa agagttagat gaatcagcga ttattgacgg
    16201 atgcagcaag tatagtgtct ttaccaaaat tatttttcct ttgctgaaac cttcgatcat
    16261 cacgacgatc atcatccagt tttattggaa atgggacgac ttcatgggac cattgattta
    16321 tttaaacaag ccgagatctt acacggtatc gattgccatc aaattatttg cagacgctgg
    16381 atctagtacg acttacgcga gtatgtttgc gatgtctacg ttgtcgctgc taccggtttt
    16441 tctgattttc ttattcttca ataaatatct tgtccagggg atcagtacaa gcggtctgaa
    16501 gggctgaata tgaaaaagcc aatagaagag atgtttcttt acaagctcaa ctactatgtc
    16561 tgtcggattt ttttaaccag tcttatcagt aatgctcttt tcgctttagt tctaggatgt
    16621 ttgttcactt taggattagt gctgtctgct cgtgttgtct atctgattta ttttttgatg
    16681 atgtatcctt cttattatct atctgtccat tacttggcag aaaaaaaggt atgttggagg
    16741 aaaggaaaaa tcaaacggat gtgtttcatc attacgttgt ttcagctgtt tgtcattatt
    16801 tttgcagttg attggtattt attagtggga aagattggag cttggtatct gattcctttt
    16861 ctattgtgtc tgttgctttt tgtatcccat agttttttta gtacgctaat tgatatctgc
    16921 aaagaagata aagcagatag tcttgtttat ttgatcaaaa ggaatatctg gctgttgtca
    16981 aaaaacgtca aggggtttct gtggtattta tgccttttgt atggactgtt ctggtgtata
    17041 cagcatgatt ttttactcac tgcattactg tatccagggc tgccatttgt cacagtattt
    17101 tgcttaaaag aaaaggagaa tgactttaaa tgaagaaaaa atatgtacaa gtcggacttg
    17161 gtgggagagc gcgttttttt tatgaggcaa ttgcctctac gtatcatcaa acttgtgaac
    17221 tagtcggttt ttgtgatgta tctcaaacaa ggatggatta tgcaaatcgg atacttgtga
    17281 acaagtatgg acagaaaaaa gtaaagacat gtatgccatc acaatttgag caactactgg
    17341 atgacgtacg gccggctgaa gtcattatta cgtcagtaga tcgaacgcat catgattata
    17401 tcattcgtgc aatgaaaaaa ggatatgatg ttatttgcga aaaacctctg actatcgatg
    17461 aggaaaaagc tcaagaaata ataacggtcc aaaaacagac gggaagaagc ctgcgagtca
    17521 cttttaatta tcgttatgca ccgtatcaca cgaagataaa ggaactgata gaaagtgatg
    17581 tgattggtga tgtgttttct atccacttcg aatggctgtt aaatacgcaa cacggggcag
    17641 attatttcag aagatggcat cgaaataagc acaatagcgg cgggcttctt gttcataaat
    17701 ctacccatca ttttgatcta gtgaattttt ggttgaacag ccgtccccaa aaggtatttg
    17761 cattcggtgg attaaacttt tatgggatgc ataatgcgga gaaacgcgga gtagaaatat
    17821 tttacagtcg atgctatgga agcgaactag ctaaagctga tccatttgct atagacctgt
    17881 cagccaatga ggaattgcga gaaatgtatt tagaagcaga aaaagacagt ggatatattc
    17941 gtgaccgcag tgtattttcc gatgatatct ctattgaaga tacactaggc gtaacggtca
    18001 aatatgaaac tggtgcgatt ttgacgtatt cgctaaacgc gtatatgccg tgggaaggat
    18061 tcaatgtttc tttcaatggc agcaaaggac ggatcgaaat gaaagtgatc gaaaagtctt
    18121 acatcaatgc aggtggagat aaaaaggatg aaggagcagc cgttcttcag tccatccatg
    18181 tctatccgat gttcggtgag ccatatgagg taatcgtcga acaagaagcg ggcggacatg
    18241 gcggaggaga tccgcgttta ttagatgatc tatttggtga agaaaaagaa gaagatccgt
    18301 ggaatcgggc agcaactcac gtagatggta ttttgtcgat tttgacagga atcgcagcaa
    18361 atcattctat tgcttcagga aaagcagtag tgattgacga gcttgtcagc ttaaaagaat
    18421 aagaatagat ttacggaaat tacttcccgt agtttataaa atcttgcctt attgccgata
    18481 ggctgtcttt tgaacactat ttattcggaa aaaggggcta tgacatgctt tttgtcatgc
    18541 cttcttttta tgtgggctgc ttttttagat aggagaaaat aaaaataact atttaaaccc
    18601 gaacaaaaag gaataatgca ttaaaaatca ttagatttta caaaaaaata agtaaaccac
    18661 gttgtcagtt tcagaaagta gtgttagact gttttcaata tttgaaacaa cattttttat
    18721 tcaaatatgg caaactgcct tcacgtgcaa aacagttgca agaaaatgaa tttacactat
    18781 tattagtttt acatacctac ttatatatcg tcataatatg gatgacagtt tctagccagt
    18841 accgtaaatg ctggactata agtaaaagat tggctatttc acccttcttt tcttatgata
    18901 aagtggaggg tgtttttctt taacagaaac atagtaggtt tttgcacaaa agcggttatt
    18961 tcggtattaa taaatgataa aggagcaaat aaagtgaaag aattagttga acgtattcaa
    19021 aaagacggac gtatattagg cgagggcgta ttaaaagtcg acagcttcgt cactcaccaa
    19081 gtagaccctg tattgatgga acaaatggga aaacggtttg cagaagtatt taaagaacaa
    19141 ggaatcacga aagttgtgac cattgaagct tctgggatcg caccagcttt atttgctgca
    19201 agagaattag atgttccaat gatcttcgct agaaaagcaa aaagtttgac gatggatgaa
    19261 gaattattga cagcttctgt ttattctttt acgaaacaag tgacaagtac gatttctatt
    19321 tctcgtaaat ttttatcttc agaagacaaa gtattgatta tcgacgattt cttggcaaac
    19381 ggacaagcgg caaaaggatt gatcgaatta tgccagcaag ctggagcgca agtagaagga
    19441 atcgggatcg tcatcgaaaa gtctttccaa gatggacgtc agttacttga agaaatggga
    19501 ttgagagtcg tttctcttgc gcgtattgct tccttgacga atggacaagt tgagtttctt
    19561 gaggaggacg cataatcgtg gaaaaagaaa cacaaaatgg aaaagctgcg gttttagggc
    19621 tgcagcatct gctagcgatg tatgcaggag cagtagcggt gcctcttttg atcggtacag
    19681 gactaggctt taatcaagaa cagatgactt atttgatttc aattgatatc tttatgtgtg
    19741 gattagcgac attattgcaa ttgacagtta accgattttt cggaattggc ttgcctgtcg
    19801 ttttaggatg tgcgatccaa gcagtagctc cactgatctt gatcggaacc aatgaaggag
    19861 taggagctat ctacggatct attatcgctt ctgggatctt tgttgtgtta gtttctggtg
    19921 tcttttctaa aattaaaaaa ctattccctc ctatagtaac aggaacggtt atcaccgtta
    19981 ttggtttgac tttgattcct gtagcaatcg agaaaatggg tggaggtaat gcaacagcag
    20041 ctgattttgg tgacaaaaca aatctgctac ttgcatttgt gacgattctc ctaattgtag
    20101 gcgtgcaaat gctggcaaaa gggttcattc gttcaatcgc ggtattgatt ggtttagtcg
    20161 gaggaagcat cttagctgct ttcatgggaa tgattgatct gagcgcgatt ggagatgcgc
    20221 cgttgttcca tgttccacaa cccttttatt ttggtaaacc aactttcgac gtatggtcga
    20281 ttttactaat gatcatcatt tccatggtca gcatggtaga atcaacaggt gtatattttg
    20341 cacttggtga cattactggg aaaaatgttg gagaagaaga attgaaaaag ggatatcgtg
    20401 cagaaggact tgccgttatc ttaggcggta ttttcaatac attcccttat actggctttt
    20461 ctcaaaatgt cggattggtt caactttcgg gaatcaaaac aagaaaaccc atctatttct
    20521 ctgcattctt cttgattgtt ttaggattat tccctaaaat cggtgcgtta gcacaaatca
    20581 tccctgagcc ggtacttggt ggaggaatgt tagtcatgtt cgggatggtg gcagtccaag
    20641 gaatccgtat gctgttggaa gttgatttca gcaatgataa aaatctattg attgttgctg
    20701 tttctgttgg atttgggctg ggtttcaatg ttacgccgac attattcagt caaatgccgc
    20761 aaacattgca aatgttcact ggaaatggca tcgtaatgag tagcattacg gctatcatat
    20821 tgaatttgat ctttaatgga ttgaaaaaag atgaagaaat attggaagaa gccttcaaga
    20881 agtaatagag caaaagaaag gttgtgaaat cagcgttttg acctgattgt tagagaaaca
    20941 aacggaaaaa tagttcctcg tattttgccg tttgtttgag ctaataccga gggtcagctg
    21001 attgaacacc gttgaaggaa gaggtcgtga gcctgccgtt catctccgag tcacaaggaa
    21061 caatttcaaa aaaaagcttc tcatgtttgt tgaatattgt tccttgtgac cgaggagttg
    21121 gcaggagaac accgtttatc cataaaaagg aatgtgacct aacttttgtc acattccttt
    21181 tttttatctt taataaacac gaacaataaa atgtttttct ttgttaacat tcgaaatttc
    21241 tttgacatca aaaaaagtga ttgttaaaat atgaatgtag aaaaactggg aggaaaaaca
    21301 atgacagcaa aaatctctgt gattatgggg agtacttcag attgggaaac aatgaaagaa
    21361 gcatgtcaaa tattggatga attcggtgtg tcttatgaaa aaaaggtcgt ttctgctcat
    21421 cgaaccccag atttgatgtt tgaatatgca caaaacgctc gaaaaaaagg aatcaaaatc
    21481 attattgcag gagcaggggg agccgcgcat ctgccgggta tggtcgcatc aaaaacaact
    21541 ttgccggtta tcggtgtacc ggtccaatca cgaacattaa atggtttgga ttcgcttctt
    21601 tcgattgtcc aaatgcctgg aggagtacct gtagctacta cagcaatcgg aaaagcggga
    21661 gcaattaatg ctggactact tgcgatacag atgctttcca tgtatgattt agaattggag
    21721 gctaaattgg ctgaaagacg ttcaatgttg gctaaaactg ttatagaaag tagtgatcaa
    21781 cttggttaaa cctttgttgc ctggttcaac gatcgggatc gtcggtggcg gtcaattagg
    21841 tcgtatgatg gcgattagtg caaaagaaat gggctttaaa gtaggtgtgc tggatcctgt
    21901 gagcgattgt ccagccgcac aagttgcaga ttggcacatt gaaagtgtct atgatgacac
    21961 ctttgcgctg aaagagcttg ccagaagaac agatgtcatt acctatgaat tcgaaaacgt
    22021 cagtgtagag gcgttaaatg cgattttacc catgtcattt attcctcaag ggacagactt
    22081 gcttgcgatt acgcaagacc gcctgttaga aaaatctttt ttggaaacga ataacatcgt
    22141 gattgctcct tatgcaacga tcgtcagtcc gacggatatc caagatgcga ttgacgggat
    22201 cggctatcct tgtgttttga aaaccactcg aggcggctat gatggcaagg ggcagtatgt
    22261 tttgaaaagt cgggcggatc tagctcctgc catggacctt ttaagagaag gaacctgtgt
    22321 tttagaagca tggatcccgt ttgaaaaaga gatttcgatc atggtggcag gaaatggtca
    22381 aggagatttc acgacttttc cggtcgtgga aaacatccac cacaacaata ttcttcatga
    22441 aacgattgct ccagccgcga ttgatcagga tgtgatcgag gaggctgagc gtattgcccg
    22501 tgtgattgca gaagcagtga gcctttcagg tgttttaggg gtagaaatgt ttttaacaaa
    22561 aacaggcggg ctatatgtga atgaattagc tcctcgtcct cacaattctg gacattattc
    22621 tattgaagct tgttctatga gtcagttcga tgcccatatt cgaggtattt gtggttggcc
    22681 attaggagaa aaagtacgtt tgataagcaa tgcagtaatg gtcaatgttt tgggagaaca
    22741 actgctggaa agctatcgct tgattgagaa taagccagac tggcaattcc atttctatgg
    22801 aaaaaaacaa gcaaaaaaag gtcgcaagat gggacatatc actatcttga cagaagacat
    22861 ccagcaaacg ctggaagaaa tcaaacaaac gaatatttgg gattagagga gaaaaaacat
    22921 gttagaacgt tatacacgcc ctgaaatggg gaatatctgg acggaagaga acaaataccg
    22981 tgcgtggctc gaagtcgaga ttttagcaga tgaagcttgg gcagaacttg gtgaaatccc
    23041 gcaagaagat gtgaaaaaaa ttcgtgagca tgcatcattt gatatcgatc ggatcttgga
    23101 aatcgaaaaa ttaacacgcc atgatgtcgt tgcgtttaca cgagcggttt ctgaaacatt
    23161 gggagaagaa agaaaatggg tccattatgg tctaacaagt acggatgtcg tagatactgc
    23221 ttatggctat ctcatcaagc aagcaaatga tattttacgg gaagacttga aacgttttac
    23281 ggaaatcatt ggcgaaaaag caaaagaaca caaatataca gtgatgatgg gtcggacaca
    23341 cggtgtccat gctgaaccaa ctacttttgg attgaaactt gccacatggt attcagaaat
    23401 gaaacggaac atcgaacgat ttgaacatgc ggcaaaagga gtagaagcag gaaaaatctc
    23461 aggagcagtg ggaacgttcg caaatatccc gccatttatt gaagagtatg tatgtaaaca
    23521 attggggatc cgtccacaag aaatctctac tcaagttctc cctcgggatc tacatgctga
    23581 atatttctca gcgatggcgc ttattgctac aagtattgaa cgttttgcaa cagagatacg
    23641 cggattgcaa aaatccgaaa cacgtgaagt agaagaattt tttgcgaaag gtcaaaaagg
    23701 ttcttctgct atgccgcaca aaaggaatcc gatcggttca gaaaatatgg ctggtctagc
    23761 cagagtggtg cgcggacaca tggtcactgc ctatgaaaat gtcacattat ggcatgaaag
    23821 agatatttct cattcttcag cagaacgaat catcttgcct gataccacga ttttattgaa
    23881 ttacatgtta aatcgttttg gcaatatcgt taaaaatcta acggtctttc ctgaaaacat
    23941 gaagcggaat atgtctgcaa catttggttt gatttatagc cagcgcgtta tgctgaaatt
    24001 gatcgataag ggaatgacaa gagaagaagc ttatgatctt gttcagccaa aaactgcgta
    24061 cgcttgggac aaccaagtgc agttccgccc gctgttagaa gaagatccaa ccatcacatc
    24121 ggtattatct aaagaagaaa tagacgatgc ctttgattat catcatcatt tgaaaaacgt
    24181 tgacgtgata ttcaaacgag taggtttgga ataaagaaga gtgagttgca aaattcaatt
    24241 aaaatagaat agcaaaaata atcgagtaga ggggaaagcc aactgacctt ccgcccctct
    24301 cacaccaccg tacgtacgga cccgtatacg gcggttcaat aagttgagtg tacgaactgg
    24361 tacttcaagg agatgtcctc atatccttgg cgggccagtt ctttgtctgt taatgatcga
    24421 tgaagaatat gacttttgga gactgaccaa ataccttttc ttgtatttga ccattcatac
    24481 gctttcgctt tatcgatccc taaacgaatc agattttttc ttttggttct tggattcttc
    24541 cattgtttcc aaatatattg tctgattctt cgcttcaacc aaccgtttaa ctccctcatg
    24601 aattctttca tctcaccaat tccatagtag ttgatccaac cagtcattag ttgcttgatt
    24661 tcttttaaaa taagttggat acttcttcca cggtttcttt tagtgagttg tttgagcttg
    24721 cttttcacac gctgttttgc ttttgcgtga gggcgaattt taataccttt ctttgttggc
    24781 agaatgcaga atccaagaaa ctttcgtttc aatggacttc ctaccgcact cttttctcga
    24841 tttaccgtca actttagttg ttcttcgaga aattgaatgg atttcttcat cacacgctgt
    24901 cctgctcgtt tgcttctaac atagatattg cagtcatcgg cgtatcgaac aaatttatgt
    24961 cctagatttt ctagcacttg atcaaattcg ttcaggtaga tgttacttaa caggggagag
    25021 agattgcctc cttggggcgt tccttcttca gttgttgtga tgagtccatt ttccattaca
    25081 ccactcatta agtattgacg gatcagtttt aggacttgtt tgtcctttac tttccgctca
    25141 atgaaataca tcagcttatc gtgatttacg gtgtcaaagt aggctttcat atcaatgtcc
    25201 accacatatc ggtaaccttg ttcataataa gattttgctt tcttcactgc gtcatgtgcg
    25261 ctgcgatttg ggcgaaaccc ataactatta tctgagaatt ctggttcaaa tagcggttgt
    25321 aacacttgat tgattgcctg ttgaagcata cgatcaataa ccgtgggaat tcctagtttt
    25381 cttacaccgc cgtttggttt cggtatttct actcgcaaaa caggctgagg tttatagttc
    25441 ccttggcgta aattggatag taattcctcg cggtgctctt tcaagtaagg aagcagttga
    25501 tcgacggtca tcccatctgc accagccgcc cctttatttc tgactacttg aagatacgct
    25561 tgattgagat tattccgatc tagaattctc ccaaacagat tttctacacc atcttgtttc
    25621 ctctgttcac cgcaagaagt gctgcgcact tcatcatacc cttcgtgttc cacactagct
    25681 ctttgatgat agccaagttt tcttgttttc tgcggtcgtc gcatcttctc acacctccta
    25741 aattattcaa gattcttatt gttcagtcct tcgtaacggt cagtgtcgtt actactatga
    25801 cctcggctga cttctcatga ttcaccatca tgtcgccatg atcgttgtgc tggtttgttt
    25861 tcattcaacg cccacaacac cctcatgaga tctcccccgg taagagtgaa aactttcctc
    25921 ccatgtaact gctagattta ctgtataggt ttcgggcagt attggacttt gtcttgtgat
    25981 gaagacttat ccgacctaat tcagccttgt atctagtttc tgttcgtcag ttcaggagtt
    26041 tgcgtccgac ttccttcagc cacaacctca cgattgccgc cttgtctttc gctaacagtt
    26101 cctactgcca agcctgtagt ggactttcac caccaagttt tcacccatgc agggcgcaca
    26161 ccaaaaaaga agcagatccg ttagcggttc tgcttctttt agtttattat attttcttat
    26221 caataatagg aacctgattt taaaagcggc tacctcttta ccgtgcctct ttacatacaa
    26281 aaaatagagg aattaagcgt aaatggcttg gctattataa ctaaaatgct ggttatggag
    26341 atgttgcagc aagttttcga gaaaagcgta ttccatctct tgtccattga ataagatctg
    26401 gatacgataa tgatttttga aacgcttctg ttcatgaatc tgactgattg aaagttcgcc
    26461 tttgtgttct gtctgataaa gaaaagtcct tttacggcat tcagcacagc gcttggttgc
    26521 tcggcggatt tttcggaatg tataaaaact agtatcttta ttgcataaat aaacgtcttt
    26581 gatcgacagc aaatcattat atagacagga acgttcttca gctgttaatt ctgataaaaa
    26641 aagctgacct tgttttattg catcttccat cggcaagtgc ctcctcgaac ccattatcca
    26701 aatttttagt taattctaat ataccatcat taagtataaa tgtaaacgct tgttgatggt
    26761 ataagatttt cgtttctgat aaaacacgaa cattaaaaga atctaatgcc ttaaatgtac
    26821 atatttttgt tgatttataa aaagatgatt gctaaaattt aaagtgaaaa aacgaacaaa
    26881 aaacgatgta tttgctttta atgtaaataa aaaggagaga cgtacatgga gaagaaagaa
    26941 cttttgtatg aaggaaaagc caaaaaaata tatcttactt ctgatgagaa cttgatttgg
    27001 atagaatatt tagatcaagc aactgcgttg aatggcgcga ggaaagacca gataagtgga
    27061 aaaggagaat tgaataatca aatcacaagt gcaattttcc gttatctgac tcaaagagga
    27121 ataaaaaatc attttattga acaattgtct aaaaccgaac aattagcaaa aaaagtacaa
    27181 attatccctc tggaagtggt tatccgaaat attgcagcag gaagtttctc aaaacgtcta
    27241 ggtgttcccg aaggtaaaga attcatcaaa ccaatcattg aattctacta taaggatgac
    27301 cagttggatg atccatttat caatgaagag catatctatt tcttacaact tgcaaagccg
    27361 gaagaaatca gtgagctgaa agcccaagcg ttggctatta atgaaatttt gaccgaatta
    27421 tttgctaagg tcggtttggt tttagtagat ttcaagctag aatttggccg gtcgaatgga
    27481 caaattttgc ttgcggatga agtaacaccg gatacttgcc gattatggga tgaacgtacg
    27541 aatgaacata tggacaaaga cgtttaccgc agagatctag gtgatttgat cccagtctat
    27601 caagaagtat ataaccgtct atcggaacta actgaagaaa aggagcgagt atgatgtatt
    27661 tcgtaaaagt atatgtaacc tataaagatt cagtgttaga tcctcaaggg gaggcagtaa
    27721 aaaaagcagt ccatcgtatg ggatatgaaa caatcgaaga tatccgaata ggaaaatact
    27781 ttgagataca acttgctgat gcagaagaac caatcgatac agtgattgaa acgatttgtg
    27841 acaagctgct tgcaaatgta aatatggaaa cataccgata tgaaatcaaa aaaatggagg
    27901 aagtataaca tgaaatttgc ggtcatcgtt tttccaggtt caaattgtga cgcagatatg
    27961 ttatgggcag ttcgcgagat catgggcgct gatgccgaat ttgtacggca tgatgagtcc
    28021 tctttagaag gatttgatgg ggttttactg ccgggaggat tctcctatgg tgactatttg
    28081 agatgcggtg cgattgctcg gttttctaca atcatggaag aagtgattcg ttttgctgaa
    28141 gaagggaaac cagtattcgg tacatgcaat ggattccaga tattgacaga agcaggactt
    28201 ttgccaggtg tactgagacg aaatgagtct ttgcatttta tttgcaaaac tgtaccattg
    28261 aaagtcaacc ccaagacggc ctttacttca gagtatgaag ccgacgaaat aatctatctt
    28321 ccagttgctc atggggaagg aaattatttc tgtgacgaag aaacacttca agaactaaaa
    28381 aaaaataatc agattgcctt tacttataat gacaacatca acggcagcgt ggaaaacatt
    28441 gcagggatta cgaacaaagc agggaatgtg ttaggaatga tgcctcatcc agaacgtgca
    28501 gtagaagact tgctaggatc agaagatggg aaacggttct ttgcttccat tttaaaaaac
    28561 ttcggaaagg tgaccgtata gatgaaaaca ttgaaagaac cgacagctga agagatcaag
    28621 aaaaaaagaa tctatgccga atggggattg actgatgaag aatatcgaat gatcgaagaa
    28681 gatatcttag gaagaatgcc taattatacg gaaactggac tgttttctgt tatgtggagc
    28741 gaacattgtt cctataaaaa ttctaaaccg gttctacgca aatttcctac tagtggacct
    28801 catgtgttgc aaggccctgg agaaggcgca ggcatcgtcg acatcggtga tggactagca
    28861 gttgtcttca aagcagaaag tcacaatcat ccttcagccg tggagcctta tgaaggagct
    28921 gcgacaggag ttggcggaat catcagagat attttcagca tgggggctcg tccaattgcg
    28981 ttgctagatt cattgaggtt cggcgaatta gataatccaa gaacgaaata tttactagaa
    29041 gaagtagttg caggtatcgg cggatacggc aattgtatcg gcataccgac tgtaggcggc
    29101 gaaattgcat ttgatccttg ttatgaagga aacccattag tcaatgcaat gtgcgtaggt
    29161 ttgattgaac acaaacatat ccagaaaggg caagccgctg gcgtcggtaa ttcgatcatg
    29221 tatgtaggtg caaaaacagg tcgcgacggt atccacggag caacttttgc ctcagaagaa
    29281 tttaatcaag aagaagaaca gcaacgttct gctgtacaag taggcgatcc ttttatggaa
    29341 aagctgctgc ttgaagcgtg tttggaatta atcttgcatc attcggattc tctaataggt
    29401 atacaggata tgggagcagc aggacttgtt tcatctagtg cggaaatggc ttcaaaagct
    29461 ggctcaggac ttatattgac attagatgaa gtcccacaaa gagaaactgg gatgacacct
    29521 tatgaaatga tgttatcgga atcacaagaa cggatgttga tttgtgttaa atcaggagag
    29581 gaagaaaaaa tccaagaact atttcagaag tatgatctag atgcagtcac tatcggtaaa
    29641 gtaacagacg acgggcaata tcggctatat catcaaggag aagaagtagc aaatctgcca
    29701 gtcgatgcat tagctgaaga tgcaccagtt tatcataaag aaatgaaaga accagctcga
    29761 atcgtagaat ttcagcagtt agctccttat cagccagtta tcgaagaacc tggacaagta
    29821 ttgcttgatc tgctgcagca accgacgatt gcttcaaaac gttcaatcta cgaaacttat
    29881 gattcacaag tacaaaccaa tacagttgtc cgtccaggaa gcgatgctgc tgtgatgagg
    29941 gttagaggga cgaataaagc gttagctatg accacagact gcaacgcgcg ctatctgtat
    30001 ttggatccaa aaatcggagg acaaatagca gtggcagaag ctgctagaaa tattattgct
    30061 agcggtggta agcccttggc gatcaccgac tgcctgaact atggttctcc tgataaacca
    30121 gaagtttttt gggaattatc gacttcagct gacggaattg ctgctgcgtg tgaaacgtta
    30181 ggaactcctg ttatttcagg aaatgtctct ttatataatg aaacggatgg tcaagcaatc
    30241 tatccaacac caatgattgg tatggtcgga ttgattgagg atcataaaca tatcactact
    30301 caggaattca aaaaatcagg ggatctaatc tatatattag gtaagacgtt tgcagatttt
    30361 gatggcagtg aattacaaaa gatgcagctt ggaagaatcg aaggtgtgat ccgaaacttt
    30421 gatctatcca ttgaaaagag aaaccaagag ttagtattga cagccatcca aaacggattg
    30481 attgaaagtg ctcatgactg ttcagaaggt ggcttggcaa ttgcactggc agaatcagct
    30541 ttcaaacatc agctagggat atctgtacag tttgaattgt cctctgctca attatttgca
    30601 gaaactcaat caagatttgt gttgacagtc gcaccggaaa ataagacacg attcgaagaa
    30661 atgatgggag atgctgctgt tttagcaggt aaggtgacgg atgaagcgat aatcgaaatt
    30721 tcagcaactg acggtcagat caaaatagaa actgcagtag caagaaagtg ctgggaggat
    30781 gcaatcgtat gtcttatgaa gtgaagagtt taaatgaaga atgcgggatc ttcggtgttt
    30841 ggggtcatcc agacgccgct agtgtggcat acttcgggct ccatagtctt cagcatcgag
    30901 gacaagaagg tgcaggtatc gtgtccaatg atcgaggaaa gcttaagggg catcgagatt
    30961 tggggctgct ttctgaggta ttcaaagatc aaagaaaatt gcagcagtta acaggagaag
    31021 ctgcaatcgg acatgtacgt tatgcaacag caggcaatgg aagtgtggac aatattcagc
    31081 cttttctatt caaatttcat gatcagtcga tcggcttagc gcataatggt aacttgatca
    31141 atgctcgttc ccttagaaaa gagttagagg aaaatggggc gatcttccat tctaactccg
    31201 atacggagat attgatgcat ttgatccgac gaagtgaaga aacagatttt ttaaataaat
    31261 taaaaagtgc tttgaatgaa gtcaaaggtg gctttgccta tttattaatg acagaaacgg
    31321 caatgattgc cgctttggac ccaaatggtt ttcgtccatt agcaatcgga caaatgaaaa
    31381 acggagcata cgtgattgcc tcggaaactt gtgcattaga agttattggg gcacgtttta
    31441 taagagatgt ccagcctggt gagatagtga tcatcaatga cgaaggaatc cagattgatt
    31501 gctttacgaa ggacacgcag ctttctattt gttcgatgga atatatctat tttgccagac
    31561 cagattcaaa catcgcaggg atcaatgtgc atactgcacg gaaaaatatg ggacggaatt
    31621 tagcgaaaga atcgccagta aaagcagata tggtcgttgg cgtacctaat tcttctttgt
    31681 cagccgcaag cggttatgcg gaagctagtg gaatccctta tgaaatcgga ttagtaaaaa
    31741 atcaatacat tgcccgaaca tttatccagc caacgcctga gctaagagag caaggtgttc
    31801 gaatgaaatt atctgctgta cgaggagtag tggaaggtaa aaaggtgatt atggtcgatg
    31861 attcaattgt tcggggtacg acaagcagac ggatcgtcca tcttttgaaa gaagcagggg
    31921 caaaagaagt ccatgtgagg attgcttctc ctcctttgaa atatccatgt ttttacggga
    31981 ttgatattca aacgcgtaaa gaactcattg cggcaaatca cacgattgat gaaatcaaag
    32041 aatgtatcgg tgcagattct ttaggttttt taagtgaaga gggtctgatc gaatcgatcg
    32101 gtctggaaaa agatgctccg tattcaggat tgtgtatggc ttatttcaac ggagattatc
    32161 cgacgccgtt atatgactat gaagaaaaat atcaggaatc actaaaagaa aaagtatcgt
    32221 tcttttaaaa gcagaccaag aagggagtat atgaattcaa tggcaaatgc atacgcaaaa
    32281 gctggcgtag atgtcgaagc tggatatgaa gtagtagaac ggatcaagaa gcatgtcaaa
    32341 aaaacggaac gtttaggtat gatgggcgct ataggaggat tcggcggttg ttttgattta
    32401 tcggtctttc aattaaaaga gccagtcctt gtctcgggga ccgatggcgt ggggacgaaa
    32461 ttagcagtgg caatcgaagc agacaaacac gatacaatcg ggatcgactg cgtagcgatg
    32521 tgtgtcaatg atatcttagc acaaggcgca gagccgttat atttcttaga ctacttagca
    32581 acggggaaaa atgatccgtt acgtttggaa aatgtagtaa aaggtgtagc agatggatgt
    32641 gttcaaggaa atatggcgct gattggcgga gaaacagctg aaatgcctgg tatgtactca
    32701 ggtaatgatt atgatctagc cggatttgct gtagggatag ctgaaaaatc tcaattattg
    32761 acaggagaaa cgatcaaccc aggagatgtg ttgcttggaa tagcatctag cgggattcat
    32821 tcaaatgggt actctcttgt tcgcaaaatt ttctttgagc agcagcagtt ttctttatca
    32881 tcaaaactgc cagaattgaa aaaaacactt ggcgaagaat tgcttgagcc aacgaaaatc
    32941 tatgtttctt ccttgcttcc gctgatcaaa gaaaagaaaa taaaaggagc tgcacatatc
    33001 actggtggag ggtttgtaga aaatatcccg cgaatgttac cagaatctat ggctgcacaa
    33061 atcaaacttg gctcatggcc gattcttcca atattcggct gtttacaaaa atatggtgaa
    33121 attcctgaga tggagatgta tgaaatcttc aatatgggca tcggtatggt cctggcagtc
    33181 caagaatcga aagtaaaaga aatagtacac gaaattgagc aagctggcga aaaagtttat
    33241 gaaatcggga aagtgatcgc caaagaaaaa catcgtgtgg tgtttatagg agaagaacga
    33301 tgagaatcgc tgtttttgct tctggaaacg gaagcaactt tcaagcgcta gccgattatc
    33361 tatcgaaaaa aggattggaa tcttcgattg actggttgtt ttgtgatcag cctgaagcat
    33421 atgttttgaa acgtgcaact gcgttgagtg taccggcaga ttgtttttca cctaaagaat
    33481 ttgattcaaa aaaagagtat gaagaagcaa ttttgcataa attgaaagaa aaaaagatcg
    33541 atttgatcgt attagctgga tatatgcgaa tcattggacc ggtattgctg aaaaattatg
    33601 ataaaagaat catcaatatc catccgtctc ttttacctgc cttccctggt ttgcatggca
    33661 tacgtgatgc ctttgaagct ggagtaaaag aaacgggtgt cacaattcat tatatcgacc
    33721 aaggtgtaga tactggacca atcatccggc aggaaaaagt gagaattgaa caggaggaca
    33781 cgttcgattc tttagaagaa aaaatccata gagtagagca tcgaatctat ccagaagtga
    33841 ttagtgaaat tattgaaaat ggaggctatc tgaaatgaca agagcattga tcagtgtatc
    33901 agataaaact gggattgtag cattcgccca aggtttgatt gaacaaggag tagaaatcat
    33961 ttcaacagga ggaacaaagc atgcgttgga taaagctggg atcaaaacgc tttcgatcga
    34021 agaagtgaca gggtttcctg aaatgatgga tggccgtgtc aaaacacttc atcctaaaat
    34081 ccatggtggt cttttaggaa gacgcgatct ccctagccat atggaggcaa tggaaacgga
    34141 aaatatccaa ccaatcgact ttgtttgtgt caatttatat cctttcaaag aaacgattat
    34201 gaaaccagat gtcgaaatag cagaagctat tgaaaacatt gatatcggtg gtcctagtat
    34261 gctccgtagt gcagcaaaaa accatgaatt tgtcacctct gttgttgatc catctgacta
    34321 tgaagaagta ctttcagaat tacgtcagta tgggcatact tcactttctt tcagacaaaa
    34381 actagcggca aaagtctttc gtcatactgc ggcatatgat gcactgatcg ctcaatactt
    34441 aacggattgg gtggaagaaa aagaaccgga aaaattgaca cttacgtatg aacgaaaaca
    34501 aacgcttcgt tacggtgaaa atagccatca agccgctgcc ttttatcagt ccgctcttct
    34561 ggaaaaatat tcgatcgcag cagcaaaaca actccatggg aaagaacttt cttataataa
    34621 tatccgagat gcagatgctg cgctacggat catgaaggaa tatgacgagc caacggtagt
    34681 cgccttgaaa cacatgaatc cttgtggtat tgggacagca tctacgattt tagaagcgtg
    34741 ggaagcagcg tatgaagcag atcctgtttc aatctttggt gggatcatcg ttttgaatcg
    34801 agaagtagat ctgccaacag cagaacagat gcataagctg tttctagaaa tcatcattgc
    34861 cccttcttat acacaagaag ctttggaatt actgcaaaaa aagaaaaaca tccgattact
    34921 gacagtagac tttgcgcagg aagaaaatca aaatcgagaa gaaacggtct cagtcttagg
    34981 tggacttctt gtacaagatc aagatctggc aatagaaaat gaagaagagt ggaaagtcgt
    35041 gacaaaacgt aagccgactc cagcagaagc aaaagcatta gcgtttgctt ggagagctgt
    35101 caaacatgtg aaatctaatg cgatcgtact ggcaaacgaa cgtcagacag taggaatcgg
    35161 agccgggcag atgaatcgag tcggttcagt aaaaattgcg attgaacaag cgcaagagaa
    35221 aatggaaggt gcagttttag ctagcgatgc ttattttcca atggatgatt cggttgaata
    35281 tgcagccaaa catggtataa aagcaatcat tcagccagga ggaagcatca aagaccaaga
    35341 ttctattgat atggcgaata aatacgatct agcaatggtc tttactgatg ttcggcattt
    35401 tagacattag agaggagtcg gataaatgaa cattttggtg atcggtgcag gtggtcgtga
    35461 acatgcaata agtaaaaaac ttttagccag tccgaaggtg gatacggtgt attgtgcgcc
    35521 aggaaatccg gggatgacaa aagatggtat caattgtgtc gctatcagtg agcgagatca
    35581 ttcagcgtta atccattttg ttaagaaaga ggctattgat tggagtatcg ttggtcctga
    35641 agttcctttg ttaaatggga tcgtcgatga ttttatggcg gaaggattga aaatcttcgg
    35701 tccgacaaaa gcagcagctc tgatcgaagg ttcgaaaagt tttgctaaac aattaatgga
    35761 tacttatcaa atcccgacag ctaaatccag aagttttgaa tgttacgaaa aagcagcagc
    35821 gtatatcaaa gaaaatggtg cgccaatcgt agtgaaagcg gacggcttag cagctgggaa
    35881 aggtgtagtc gtggctacca cagtgaagga agcgctggat gcggcagaac aaatgttgaa
    35941 ccagcatcga tttggggata gtagcaaaaa aatcgtcgta gaagagtttt tggcaggaga
    36001 agaattctcc cttttggcgt ttgtccgtaa taccaaggtg tatccgatgg tcatttcgca
    36061 agatcataag cgggcatttg ataacgataa agggccaaat acaggcggaa tgggtgctta
    36121 ttcaccagta ccgcaaattt caaaaaagat gattgaaaaa gctgtggaag aagttttaaa
    36181 accagcggct ttgggaatga aagaactagg acgctctttc acgggtgttt tatatgcggg
    36241 tttgattgct acgaaggaag gaccaaaagt gatcgaattc aatgcgcgtt tcggtgatcc
    36301 tgaaacgcaa gtcgttcttt ctcggttgaa gagtgacttt gcgcaagtaa tcgatgattt
    36361 attagagaat cgtacagtag agttaaagtg gcagcaagaa ggatacaatg taggcgttgt
    36421 ggttgcagct gccggttacc ccgaagaata tgagacagga atggttctac cagattttct
    36481 ggaagaagag ctttctgttt actatgctgg agtttcctca aataacggca aactagttgg
    36541 agcaggagga cgtctttatt tagtagaagc atacggtgag acgatcaaag aagcacagaa
    36601 aaaaatttac accgcgttaa tggataaaac gacagatgga acattttatc gtacagatat
    36661 tggagaaaaa gctgccaata gcgaactgat cgtgaagtaa atcagctgct tccatttata
    36721 aaaaatacaa caaacataat cggaagcgcc gattttagtg aagccttttc ataaagagtg
    36781 tggtacactt ttgttgtgta tataaataag gaggagttca gatgaaaaaa attcaattag
    36841 gtacttctga tcagaaagca gctgcagtga tcttaggctg tatgcgtatc aacaatgcgg
    36901 aagatccagt aaaagtgatt gagacagctt atgaaaacgg cattgatttt tttgaccatg
    36961 cagatattta tggaaacggt gaatgtgaag aaatctttgc agatgctcta gcaaaaacat
    37021 caatcaaacg agaagatctt tttattcaaa caaaatgtgg aatcgttcca ggtgtgatgt
    37081 ttgatttttc taaaaaacat atcattgaat ctgtagaaaa aagtttgacc cgtctgaaaa
    37141 tggattatgt ggatgcttta cttcttcatc gtccagatac attggtagaa ccagaggaag
    37201 tagctgaagc gtttgatgaa ttggaacggt caggaaaagt tcgttatttt ggcgtcagca
    37261 atcaaaaacc aatgcaaatc gaattgctga aaaaatatgt tcgtcaacca ttagtagcta
    37321 atcagctgca atttggcttg aaacatactg gaatgatcga tcaagggatt catgtcaata
    37381 tgacagatga agcaagtatc gatcatgacg gtagtgtact tgattattcc cgattgcatg
    37441 atatgacgat ccaagcatgg tcaccatacc agtatggatt ttttgaaggt gtatttatcg
    37501 ggaacgaaaa attccctgaa ttaaaccaaa cattagaaga actagcagct aaatatcaaa
    37561 cgacaccaac tggcttggct tctgcttgga ttttacgcca tccagccaat atgcaagtga
    37621 tcgccggtac gatgaacgta gggcgaatca aggaaatcgc tcaagcttca gaaattaata
    37681 tgtctcggga agattggtac gaattgtacc gtgctgctgg aaacatttta ccttaaagat
    37741 tgtcataagc aggtcaaaag ggctataaat taaaaagaca gaataacttg aaagctgttt
    37801 tcagcttcga gatattctgt ctttttttat tgcaaatgga aagagtatca ttgtacggat
    37861 ttcgtttatt agttattttt gtttttaagg aaaagctgtg tccgatattc ttttggagaa
    37921 atcccttgtt ttttcttaaa taaataactg aaatagttag ggtcattata accaatttca
    37981 aaagcaatat ctgaaatacg atagtctgat tgctgcaata atttttttgc taattcgatt
    38041 ctttgttctg tcagataatc gatgaatgtt tggttaaacg attgagaaaa aatcgtactg
    38101 aaatgagagg gacttaatgc aacttgttga gcgacccaag ttaaggacat atctggatcg
    38161 gtaaaatttt ctttgataaa atccaatgca tggttcaaaa ttggctgata tttgttcctt
    38221 gaaggctgtg agggcagagc agttaagaaa gaaatgaaca tataaactgt cgaacggtaa
    38281 agcgagtcgt cggcgctgat tgctaagcgt tgactggtgg atgtgcaatg aaccatttct
    38341 tgcgggattt tcttttcttt caggcagaca tgctggagta gcttagtcaa gacaaataaa
    38401 cgatataatc gtgttcgagt tggtgtgcct tgtggtttcg tcaagtgttc gatgtactta
    38461 gatacttcgt ttttcgataa tgaagacaaa tcaagtgaga ggtcaaagta aaagacagaa
    38521 tcaactggaa gtttcgcttc ttgaatcaaa tcctcatagc tgataatttg ttctttaagg
    38581 gaactggcgg tttcaagtat catctgcgtg atctcaaaag atgcaggtaa ttcgctgatt
    38641 ctttctgcga caggaccaat ggcgacagaa aaattatttt tttgtccctt ttctaattca
    38701 tggaccaacg tttgggctac ctgataactg gtctcgatca cattttcttc aagagaatca
    38761 actattaaaa atttgatgaa tcgagaggaa acagcagaga agatcacttg ttgattctcc
    38821 ctaaataaaa acttcaaata atcactgaga tgagcgtaat cttcaaagtc tgtactgact
    38881 tggtttgctg ctaataatac ggtcattttt ttccctgcta aagagcgatt gaaagattca
    38941 gcaagtttca atgtttcact gatcgtaagt gagcctttga acaaaccgtt caagaaatga
    39001 ttttttttca attcgaaaac aagatcagaa gaagtgtgcg tttctttttg ctgcaaatct
    39061 aaagcagtta ctgctttttc tattgcttgt ttcaattcgc tacttttaat cggtttaagc
    39121 agataatcat ctgcctgtac ctggattgct cctttcatat aatcgaaatc gtcgaatcca
    39181 ctaataaata tgagacgagt ccaaggaagt agtttccttg cttcttttga aaaagtcaac
    39241 ccgtccatga aaggcatttg gatatcagtc agaatgatgt cgggctgtaa gtcgataatt
    39301 gaagacagtg ccatctcacc atctccagct tcgccgacat aagtgattgg ataataagaa
    39361 ccaaggacag ttatttgttc ccgcaagtta ttgcgaatga ggtattcgtc ttcgatgata
    39421 aaaactttat acatgtttgt ttcctccaat tgttttggga gatagaggga tcatcagtgt
    39481 gacagttgtt ccttctcggt atttgctgtc aatcgtgata ggtttttgat catttccgta
    39541 ataaagaagg agacgcttgt ttacgttgta aagtccgtag ccgatactga aatctgaatc
    39601 gatccctttg gctaactctt tacgtatttc tgccagtttt tctgcaggga tgccaatccc
    39661 gttgtctata actttgaatt ggatcatctc atcaattttg catgtggtaa tacgaataaa
    39721 tcctttgtga cggacgtact tcgttccatg gtatacagca ttttcaatca atggctgcaa
    39781 gatcattttt aaaatagaaa caggaaaaag tgtttctggt atatcgatct tatagtcaag
    39841 catatggccg tatcttattt ttaagatgac tagataatca ttgatatggc taatttcttt
    39901 ttcaagagga atccagtctt gtcctttgct taaagacgta cgaaaaaagc cggaaagtgc
    39961 atgggtcata gtcagagctt cttcaaagca gtcttgttcg atcaaagaaa taatggcatc
    40021 caaactgtta taaataaaat ggggagtaat ctgagcttgc aatacacgaa cttcactttg
    40081 tgctaaatgg tattgtttca aagcgttctc ccgtaaagac tggtttagat cttccgccat
    40141 tttattcatg ctagcggtaa gtgtttgtaa ttccagtgtt tccggcaggg ttaaacgaaa
    40201 gccaaggttc cctgaagaaa gttgttctga catctcgatc agctgattga tcggttcttg
    40261 gacctttctc tctaaaaagc gacgattctt tttcgcatag aaaaaaatgg tactaagaac
    40321 tccaagttcc actattgtta atagaatgag cgagcggaca agtgtcgtat tttttttgct
    40381 tgctaagtcg atctccacac gaacaaaatc ttgtaagata tctgacagca gttgagtgac
    40441 agaatctacc tgattgatga tctcttcatt ggtatccata aaatcttttg ccaagatatt
    40501 attgatcagc tcgttttgat aatcttccag tgtatcgatc gtacgtagcg atacatctaa
    40561 cgtactaatt tctttaagtg tatttgtatt atttttgatc tctcgaatat cattcctaag
    40621 ttcttctagg atattttcct cattgaactc atctacggtt acttggccag aaatcaagtc
    40681 ccacatactt tccaaaactt tttgatcaac cttcaaagca attgcatctg ctttttggat
    40741 atttgcgatc gtctgttgat aaatcaaaag ctgttgcgaa tataacagta tgctcagtag
    40801 caaagggata acagcaaata gaagcatggc tttgtttgct tgggcaaaaa tctgttttat
    40861 gcttaaattt tttgtcatga tacttctcca gtcaataatt tctggttggg atgttagcta
    40921 tattctgctg ggaaaagaca gtctcggaaa taaaaatatc tttaggtaat gtttttcctg
    40981 tttgaatatt tccaaaataa cgagtaacgg tattggctac ataccagccg acatcaggtt
    41041 tacactcgac tacacaattg acgattcctg agcgtagctt ctcgatcata tcttcttgtc
    41101 catcaatagt tacaatgatc aaatcttctc caggtttgat tgatgtttct tttatcgcag
    41161 ctaaagcacc gtgagtcatt tcatcactat ggctgtataa tacatcgatt tcggataaat
    41221 catttgtttc taaatatcgt ttcatctggt cttttccttt catccgaata aaatcaccga
    41281 caattcggtg aacaatagtc atcggaggtt tatggtcgat ggttccatct ttttttaggg
    41341 ttggtttacg attgattgat tccaaaaatc cttcggagcg tagcttggtc ggtgtggagt
    41401 tctctgaacc agcaagttct aggattctga tttcctgttt ctttgaattt gtgaagtgat
    41461 tgctgacaaa taaacccgcc cgatttcctt ctgctttgaa actggggcca atgtgggtga
    41521 cgaaaagctc gggatcattc gtttgaatat gtctgtcgac aagtatgaca gggatccctg
    41581 ctcgctttgc ttcttttaat acagagtccc acccggattc ttgcaaagga gtaaaaatga
    41641 tcatatccac tttataggca atgaacgtcc gtatatcttg gatttgccgt tcctgattca
    41701 tgtagccatt tcggtagaga acttggtaat cttctttttc aagcgcagtg ataattgatt
    41761 cagtatgctt tttccgccag ctactctccg ttcctgattg cgaaaaacca acgactagtg
    41821 ggtcaggtgc ttcctttgta ttaggtgtac accccatcat ttggtaagcg attacaacaa
    41881 gggctaaaaa aaataaaaca cgtttcactt taaatcactc catctggatt tgttagtact
    41941 atcttatcag ataaaaggga aaatcaaagt caaaaggaat caatcgaaaa aaatccaaga
    42001 aacttaaaaa aatccaagac aaaaaaagta cacctaaaaa atttaaagta aatcccataa
    42061 aaaaatcaat gttaacgctt tctttattag ctatactcgg tgtatcaatt gaaatggggg
    42121 ataaaaaatg aaaaacaaat ttagaaagat tgttgggact atcgctattt tgaccgcaag
    42181 cattctatta agtgcgtgtg gcaattcagg atctgcagat gatagtacgg ggtatgtagg
    42241 aatcgctatg ccgaccaaat cagcagaaag atggatcgct gatgggaaca acatggtctc
    42301 ggaattagaa aaactgggtt ataaaacaga tcttcaatat ggagaagata aagtagaaaa
    42361 tcaagtagca caaatagaaa atatgattac aaaaggggta gatacacttg tgattgcttc
    42421 tatcgatggt tcggctttaa ctgatgtgtt agctaaagca aaagaagcag atatcaaggt
    42481 gatcgcctat gatcgtttac tgatgaattc agaaaatgtc gattattacg cgacttttga
    42541 taattttgga gtaggtgtat cgcaagcagc ttatattgaa gagcacttag gattgaaaga
    42601 aggaaaagga ccattcacga ttgaattatt tggtggctcg cctgacgaca acaacgcact
    42661 aatcaattac aacggagtga tgtctgtttt acaaccatat atggacaacg gtcagttggt
    42721 cgtgccatct ggacagacga gtttcagtca aatcgctacg cttcgctggg atggttctac
    42781 ggcgcaagca aggatggata atctgttaag cgcaaattat actgaccaaa cattggatgc
    42841 tgttttgtcg ccatatgatc caataagttt aggaatcatt tcgtcattaa aaggcgtggg
    42901 gtatgggagt gaaagtaaac ctttacctgt gattactgga caagatgcga cagttgctgg
    42961 cgttaaatcg atcattgccg gggaacaaac acaaacgatc tttaaagaca cacgtatctt
    43021 agcaaaaaat acgattgaaa tgatcaaagc aatcagtgat ggagaagagg ttccggtcaa
    43081 tgatactgaa acttatgata atggggtgaa aactgtccct acgtatttag caaatacagt
    43141 atctgtcgat aaagataatt atcaagcaga gctgatcgac accgattatt ataaagaatc
    43201 cgatctgaaa aattaagagg aaccaaacaa ggaactaaag agatctaagt cagagagagg
    43261 ataagaatta tggcggattg tattttaaaa atggcagata tcaccaaaaa attttctgga
    43321 atccgagcgt tagattgcgt gaatctgatg attgaacgtg gggaaatcca tgcattgtgc
    43381 ggagaaaacg gagcgggaaa atcaacattg atgaatgtct tgagcggctt gtatccatat
    43441 ggctcctatg acggggaaat cttttatgat ggaaagctgt gtcaatttaa agatttgaaa
    43501 gatagtgaag aaaaaggcat cgtcatcatt catcaagaat tagcactaag tccttatctt
    43561 tcaataaaag agaatatttt tctcggaaat gaacaagcag aaagaggcgt gattgattgg
    43621 gaactgacag aaaagaaaac atatgaactg ctgaataaag tcggtttgtc tatcgacccg
    43681 aatcttctag tatcccagat tggcgtaggg caacagcaac tagttgaaat agctaaagca
    43741 ttatcaaaat ccgtccgtct gttgattttg gatgagccta ccgctgcatt gaatgaagaa
    43801 gaaagcgcga atttgctgag attgatccga gagttgaaag agcaaggtgt aacctccatc
    43861 attatttcac ataagctgaa tgaaatcgtg gatatcgcag atcgaatcac cattttacgg
    43921 gatggacaga cgattgagac actagaaaat gaaatgatca gcgaagagca tattattcgc
    43981 ggaatggtgg gcagagattt agttgatcgt tatcctgaaa gaaaaccgga tattggagaa
    44041 gtttatttta aagtagaaga ctggacggtc tatcaccctc ttgatcacga gcgaatcata
    44101 aacgaccaca tcaacttgca tttgaaaaaa ggagagattg taggaatagc tggactgatg
    44161 ggagcgggca gaactgaatt cgctatgagt ctatttggac attcttatgg aagcaagata
    44221 tccggacgta tattaaagga aggggcagag atatcagtta agaccgttcc ttcagccatt
    44281 gcaaacggac tcgcttatgt ctcggaggac cgaaaatctt taggactgaa tctgctgatg
    44341 gatattcggg aaaacgtgac gctgagcagt ttggataaaa taagtcaaaa aggagtatta
    44401 gataaagaaa aagaagtaac tgaggcagaa aatttccgga aaaagatgcg tataaaaaca
    44461 aactccatcc atcaaattgt cagtagtctt agtggtggga atcaacaaaa agtcgtttta
    44521 tccaagtggc tgatgacaca acccgatatt ctttttttgg atgagccaac ccgtgggata
    44581 gatgttgggg caaaatatga gatctacacg attatcgaag aaatggcagc aaatggcaaa
    44641 gctgtctgtc ttatctcttc tgaacttcct gaaatattag ggatgtgtga tcgaatctat
    44701 acgatgaacg aaggacgtat tacaggagaa gtctcgcgag aagatgcaga tcaggaagtc
    44761 ttgatgaaat taatgacgaa agaagaggtg ggttaagttg gaacaggcaa aaaatcttac
    44821 ggataaaaaa gagaaaaaac taaatttgaa aagtagagca gctgatcttt ttggtcgcta
    44881 cagcatggtg atcattttag cgggactact tattgcgttt caattgatga cggatggtat
    44941 tttctggcgt ccattgaata taactaacct tgttctgcaa aatagccata tattagtact
    45001 agctgcaggg atgttattag ttgtgctctt aggtcatgtg gatttgtcgg tagggtcagt
    45061 gatggcgttt gttggtgcaa ttgcgggcat gatgatggtc aatcgccaaa tgaacccgtg
    45121 gatgacagtt atcgcatgtc ttgcagtagg cgggctgatc ggcgcatggc aaggtttttg
    45181 ggtagcttat gcagggatac cggcgtttat cgtgacttta gcaggattgc tgatgtttcg
    45241 tggactgaca caagttgttc taggaggcca atctctagca ccttttccag ctgttttcca
    45301 aaaaatgtct acgggttatt taccagactt aagcgaagga agcagccttc acttcttgac
    45361 attgatttta ggaatgatca tcacgatcgt gttagttgtt ggtcaatggc gaacaagaaa
    45421 tcgtcggaaa aatcatttat ttgaagtgga atctccaaca gctttcttgg taaaggcggt
    45481 atttacagca gtcgttgtac taggaataac ttatatcttt gcctcttatc aagggtatcc
    45541 gattattttg atcattcttg gtttgatcgt tgcagcatat gggtttttga caaataaaac
    45601 agtagcaggt cgacagattt atgcgacggg cggaaatcga aaagcggctg aactatcagg
    45661 gatcaaaaca aagcgaatca cgttctgggt attcgtcaac atgggagtca tggcagcttt
    45721 agctggatta gttttagctg ctcgattgaa tgcggcaaca cctcaagcag gtacatcgat
    45781 ggaactggat gcaatggcgg cagtatattt tggtggtgct tcgacttccg gcggcattgg
    45841 aacaatcatg ggtgcgattg tcggtggctt ggtcatgggt gtattgaaca atggcatgtc
    45901 gattttaggc gtcggggtag actggcagca ggcaatcaaa ggattgatct tgcttttagc
    45961 cgttgtgcta gacttgtata ataagaaaaa acgaacaacg taggagaacg ccggttattc
    46021 agaaaaaaga ctgtgacaag acatttgtca cagtcttttt ttcgctaaaa gcgaacattc
    46081 attgtttcgt ttgtatagac taaaaataat atatgttttt ttaccattcg tataaattct
    46141 ctttttgctc ttgatttttt tgcttaattg agttaaatta catagggcgc taaaaaaagc
    46201 cttgattaaa ttaataatgt tcgtgttttg ctggatgtga acatcaggag gataatgtaa
    46261 tgaaagtatt tgattacgaa gatattcaat taattcctaa taaatgtatc gtaaatagcc
    46321 gttctgaatg tgatacaacg gtcacattag gtaaacatac attcaaaatg ccagtagtgc
    46381 ctgccaacat gcagacgatt attgatgaaa caatcgcaga attcttagcg gaaaatggtt
    46441 atttctatat catgcatcgg tttgatgaag cagctcgaat tccgtttatc aaaaaaatga
    46501 aaaagcgtgg attgattacc tcgatcagtg ttggcgtcaa gaaagaggaa tattccttta
    46561 tagagaagtt ggcagaagaa tcgctaaatc ctgattatat cactatcgac atcgcgcatg
    46621 gacatgctaa ctcagttatt gatatgattc agcatattaa aaaatatttg cctgaaactt
    46681 ttgtgattgc cggtaatgtt ggtacaccgg aagccgtccg tgaattggaa aatgcgggcg
    46741 cagatgcaac aaaagtcggg attggtccag gaaaagtatg tattacaaaa atcaagacag
    46801 gctttgggac tggaggctgg caactggcag ctcttagatg gtgtgcgaaa gcagctcgca
    46861 agccgatcat cgctgacggt gggatcagaa cacatggcga tattgcaaaa tctgtccgtt
    46921 ttggtgcgac aatggtcatg attggttcat tgtttgccgg tcacgaggaa tctcctggcg
    46981 aaacaaaagt cgaaaatgga atcgtgtata aagaatactt tggttctgct tcagaattcc
    47041 aaaaaggcga aaaacgaaat gttgaaggaa agaaaatctg gatccaacac aaaggatctt
    47101 tgaaagatac actagtggaa atgcaacaag accttcaatc atctatttct tatgctggag
    47161 gaagagatct ggaagccatt cgaaaagttg actatgtcat cgtgaaaaat tcgattttta
    47221 atggagacac aatctaaaaa ataaataaaa tattaggatg ttgtgaaaaa gttgtcctgc
    47281 attaagtaat aagaacagcc aaacaaaaat agttctttat atgttttgtt tggctggaat
    47341 tattatcgca gatacaagct tttgaacatc attattcaga ataagggact gtgataagat
    47401 ttttgtcaca gtcccttatg ttttgcaaaa aaagtttttc ttttttctcg taaattcggt
    47461 aaaatcaaaa gaaaaaatag acaatagaaa agagaagctt atgtgggaaa aagtagagaa
    47521 aaaacaagga ccgatttatc gtcaaattat ggaacagatt atgagagaaa tcgaaaacgg
    47581 aaggatcaat cctggaagtc aacttgaatc agaacgaaaa ctagggcaac tttttggtgt
    47641 gaatcgttcc accgttgtcc atgcattgga agagcttagg gagcttgggg tactaacgag
    47701 caaacgtggc agcggatggt ttgttaatca gactgaatgg gggaaattcg ctgttccaag
    47761 aatcgattgg cggcaaatga tctctcctcg ttatgagcag acggactggt atgagcaaaa
    47821 aataagagaa gcaaagcaga tccaaaaaac atcgtttctt gatttatacg ctagcgagat
    47881 gccagatgag cttttgccga attttgagtt tccttcttat tctcttgaag aaatcttagc
    47941 ggaagaaaaa gaaatggatc ttttaggcta tactccgtta cgtaacaaaa tcaaacggta
    48001 tttggaaagt aaatttgaat tggcattttc ccccaaccag cttcttgtga ctggtggcgg
    48061 tcagcaagca atctttttga ttttacaaac gattctttca gctggagagg ggatagctgt
    48121 agagtcacct tctttttttt accgattacc tcttttcaaa gcttcaggaa cgcgtttatt
    48181 tgggataccg atggatgaag aagggatcga cttagaaaaa ctgaaagaat cgatccataa
    48241 aaataaattg aaagcagtgc ttatcaaccc gaattttcaa aaccctacag gaaaagtgat
    48301 gagtcaaaaa cgacgagaaa agctagtaga attgtgtcga cagtatcggc ttccaattat
    48361 tgaagacgat gtatttacgg atctttcatt tctaaaccaa gaagaagtcc ttcctatacg
    48421 aacgattgat ccggataatg tgttatacgt cggttcgtta tctagggttt taggaaaaac
    48481 aacgaaaatc ggttgggtga taggacctga gacttttatc tcgcaactag ctcaagcgca
    48541 agaaatgatg gagttttcga tgaatatcct tacacaaatc acagtggcta atgtatttaa
    48601 tgaagcaatt gatttgaaaa tgcaagatgt aagaaaaaag ttgaaagaaa aaagccgact
    48661 gataagcgct tggggagatt cacaatcgtt tttcaagctt cattcaattt taggtggtta
    48721 ctatgcctgg attacttggg atgggaaaaa actagacccc gaactagcag aaaaagtagt
    48781 agatatgggt cttggaattg caccaagtct actttttggg caagatataa atggaatcag
    48841 aatcaattac agtaggctgg atgaaaacca aataccgttg ttttattcaa agatgaaaat
    48901 tctagaaaag tggttaacag aataatttca caaagtaaat agattaaaga atataacagc
    48961 ttggatttaa atttcaagct gtttcttttt tttcggaaaa agaatacgat ataaagaaac
    49021 taagaaaaaa ccattatttg tacgtccgtt cacgatgtgt aaataaaata aatgtttgca
    49081 acaaaactgt ataacaccaa cgtttttaaa tagaaacaga tggttgtaag tttgattaga
    49141 aaatagaaaa aatgcagatg aaatataaaa cgctttcctt attgtgattt tattcactaa
    49201 tgctgttaat atgcggattg gcataatttc ctttcatcgt gaaaatttgt gcttttagct
    49261 tgtatttctc ataaatccat gataatttat taatgaagac ggttaaatag tgatacagtt
    49321 ttattcactg tttcaatcgc agaatgaaga gattttctta tagatgagag aggaatgtgt
    49381 gacaaatggc aaacaaaaaa gcaccgatcg acttccaagc actgctagat gaagtcaatg
    49441 cagatttccc agtatatcaa gcacttgatc aagatggaaa cgtagttaac aaagatttag
    49501 tacctgattt atccgatgat gaactcgttg aattaatgac tcatatggta tggtctcgtg
    49561 tattagacca acgttcaaca gcgctgaacc gccaaggacg cctaggcttt tttgcaccaa
    49621 ctgctggaca agaggcaagt cagctggcta gtgcttacgc atttgataaa gaagatgttc
    49681 ttcttccagg ttatcgggat gtacctcaac tagtaaaaca tggtttacct ttatctcaag
    49741 cttttttatg gtctcgagga catgctgcag gtaattctta tccggaagaa ttgaaagctc
    49801 taccaccaca aattatcatc ggtgcacaat atgtacaagc agccggtgtt gcattaggtt
    49861 tgaagaaacg aaacaagaaa aatgtcgtct tcacttatac tggtgatggc ggttcatcac
    49921 aaggtgattt ttacgaagca atcaatttcg ctggcgctta ccatgcaaat gccgtatttt
    49981 atatccaaaa caacgggtat gcgatctcta cacctcgtga aaaacaaact gcagcaaaaa
    50041 cacttgcaca aaaagctgtc gcagctggga ttcctggtat tcaagtcgat ggaatggatc
    50101 cgcttgcagt atatactgta tctaaaatgg cacgggaatg ggcgatcagt ggaaatggac
    50161 cagtcctaat cgaaacactg acttatcgtt atggaccaca tacactatct ggtgacgatc
    50221 caacccgcta ccgtacaaaa gacacagatg acgattggca gaaaaaagat ccattgatcc
    50281 gcttccgtaa atatttgacg gaaaaaggac tttggtctga agaaaaagaa gaacaagtca
    50341 tcgaagcaac taaagaagaa atcaaagcag ctattgctga agccgacaaa gtaccaaaac
    50401 aaaaggtttc agatttcttg aaaaacatgt tcgaagtatc tccacaatca atcaaagaac
    50461 aaattgcaat ttatgaagcg aaggagtcga aataatcatg gcacaaaaaa caatgatcca
    50521 agcaatcaca gatgccttag cacttgaact agaaaatgac gagaatgtcg ttgtttttgg
    50581 tgaagatgtt gggaaaaacg gaggagtttt ccgggcaact gaaggattgc aggaaaagtt
    50641 cggagaagac cgagtattcg atactccttt agctgaatct ggaatcgcag gattgagttt
    50701 cggtcttgcg ttagaaggat ttcgtccagt tcctgaaatc caattctttg gttttatttt
    50761 cgaagcaatg gacgaagtag tagctcaaat ggctcgtaca agatatcgaa tgagcggcac
    50821 tagaaatcta cccatcacaa ttcgttcgcc atttggtggc ggtgttcata caccagaatt
    50881 gcattcggat aatttagaag gtttgatcgc tcagtctcct ggtattcgag tagtgattcc
    50941 ttccaaccct tatgatgcaa aaggactatt gatttcttct attagaagta acgatccggt
    51001 tgttttccta gaacacatga aactatatcg ctcattccga gaagaagtgc cggatgaagc
    51061 ttacgaagtt cctttggata aagcagcagt tactcgtgag ggaacagatg tatctattat
    51121 cacatacgga gcaatggtgc gtgaagcaat caaagcagca gacaatcttg caaaagaaaa
    51181 tatatctgtt gaaatcattg atcttcgtac agttgcgcca ttagatgtag aaacgatcat
    51241 tcaatccgtg gaaaaaactg gtcgcgtagt tgttgtccaa gaagcacaac gacaagcggg
    51301 cgttgccgcg caagtagttt ctgagatctc agaacgcgct atcctttcat tagaagcccc
    51361 aatcggacga gtttctgcac ctgatacagt cttcccattt ggacaagcag aaaatgtctg
    51421 gttgccaaat gcaaaagata tcgaagacaa agtaaaagaa atcgcggaat tttaagaaaa
    51481 gaagggacga aacaaagtca tggcttatca atttaaattg ccggatatcg gtgaaggaat
    51541 cgcagaaggt gaaatcgtca aatggttcgt caaaccagga gatacgatca atgaagatga
    51601 tacattacta gaagttcaaa atgacaaatc agtagaagaa atcccgtcac ctgttacagg
    51661 aacggttaaa aatgtgattg ttccagaagg taccgtagca aatgttgggg atgtattagt
    51721 agaaatcgat gcaccaggac acgaagacaa tgaaggggac agtggtgtag ccgcagaatc
    51781 ccaaactcca gctaaaccgg ctgctgaacc cactgttgat acagaatcag ctggatcgtc
    51841 aagcgaagga gtcttccaat ttaagttacc ggatatcggt gaaggaatcg cagaaggtga
    51901 aatcgtcaaa tggttcgtca aaccaggaga tacgatcaat gaagatgata cattactaga
    51961 agttcaaaat gacaaatcag tagaagaaat tccgtcacct gtcacaggga cagttaaaaa
    52021 cgtgattgtt ccagaaggca ctgtagcaaa tgttggggat gtattagtag aaatcgatgc
    52081 tcctggacac aatagtgcac cgtcaactag tgcgccatca gctgaagcac caaaagaaaa
    52141 agtggaaaca tcaggttcag caagtgtcgt tgaagctgcc gatccaaata aacgtgtatt
    52201 ggctatgcca tctgttcgtc aatttgcccg tgaaaaagat gtagatatct cacaagtaac
    52261 tgcaactgga aaaggtggca gagtaacaaa agaggacatc gaaaacttct tggcaggtgg
    52321 tccaagcagt gcaccagcga aatcagaagc gccagaagcg gcagcaccga aagaagcagc
    52381 tcctgcagca gaaagcaaac cagctgcacc agcaaaacca ttcaagtcca acttaggaga
    52441 cttggaagaa cgtgtagcaa tgacgccaac acgtaaagct atcgctaaag caatggtcaa
    52501 cagtaagcat acagctccac acgtgacatt gcatgatgaa gtagaagtgt ctaaactatg
    52561 ggataatcgg aaacgattta aagaagttgc tgctgcaaat ggtacgaaac ttactttctt
    52621 gccatatgtc gtgaaagctt taacagcgac tgttaagaaa tacccagtat tgaatgcatc
    52681 tatcgacgat gcaaaccaag aaatcgttta taaacattac tacaatatcg gtattgcaac
    52741 tgatacggat cacggactat atgtaccaaa tgtgaaagat gcagaccgca aaggaatgtt
    52801 tgctattgca gacgaaatca atgagaaagc aaaattagct catgacggca aactatctgc
    52861 agaagatatg cgcaatggaa caattacgat cagcaatatc ggatctgtag gtggcggttg
    52921 gtttacacca gtcatcaact atccagaagt agctatttta ggtgtaggaa cgattgcaca
    52981 acaaccaatc gtaaatgctg aaggcgaaat cgttgtcggt cgtgtgatga aactgtcatt
    53041 aagtttcgat caccgtatcg tagatggagc aactgcgcaa caagcaatga ataatatcaa
    53101 acgtctttta gctgatccag agctattaat gatggaagga tgataaacaa atggtagttg
    53161 gagattttgc tgtagaatta gatacagttg taattggtgc gggacctggt ggctatgtag
    53221 ctgccatccg cgctgctgaa atgggacaaa aagtagcaat cattgaaaga gagtatattg
    53281 gcggtgtttg tttgaatgtc ggctgtattc cttcaaaagc actgatagct gcaggacacc
    53341 attatcaaga gtcactagat tctgaaatgt ttggagtaac tagtgaaaac gtcaaactag
    53401 attttgcaaa aacacaagaa tggaaagaaa acaaagttgt ccatacgttg acttctggtg
    53461 ttggtttcct attaaaaaaa cataaggttg aaacaatcga aggagaagcg ttcttcgtag
    53521 atgatcacac actacgcgtc attcatccag attcagctca aacttattcg ttcaataacg
    53581 caatcatcgc aacaggttcc cgtccaatcg agattccagg atttaaattc ggaggacgtg
    53641 tgttagattc tactggcgga ttagcattga aagaagtacc taagaaattt gtgatcatcg
    53701 gtggcggtgt gattggtgcc gaattgggcg gagcgtacgc aaacttagga gcagaagtaa
    53761 cgattcttga aggctcacca caaattttac caacttacga aaaagatcta gtaaaattag
    53821 tagaagatga tttcaagaaa aaaggcgtaa cagtcgtaac gaatgcaatg gcgaaagaag
    53881 cagtcgataa cggtgacagc gtgacagtga aatatgcagt ggacgggaaa gaagaatccg
    53941 ttactgctga ttatgtgatg gtcactgtag gtcgtcgtcc gaatacagat gatatgggct
    54001 tagaacaagc gggtgtcgaa gtaggagaac gaggattgat cacggtggat aaacaaggac
    54061 gtacgaacgt acctaacatc tatgccatcg gtgatatcgt tccaggggcg gcattagcac
    54121 acaaagccag ttatgaagca aaaatcgctg ctgaagcaat ctctggcaaa aaagtagctg
    54181 tagattataa agcaatgccg gcagtagcct tcactgatcc tgaattggct tctgtaggta
    54241 tgacgatcaa agaagcaaaa gatgctggta tcgaagcaaa agcatataaa ttcccatttt
    54301 cagggaacgg tcgggcatta tcgcttggta aaacagaagg attcatccgt ctagttacga
    54361 cgatcgaaga taacgtgctt attggcgcgc aaatcggtgg agtcggcgca agtgatatgg
    54421 tctctgaatt agctttagca atcgaatcag gaatgaatgc tgaagatatc gccttgacga
    54481 ttcatcctca tccatctctt ggcgaaatcg tcatggatgc ttcggaatta gcattaggtt
    54541 taccaatcca tatttgattt gaataataca ggcgaaacgc aactgaaaaa tcagttgcgt
    54601 tttgtttttt agaattatca ataatattat tatgtaaact taaaaatatg acaacttctt
    54661 ggtttattac cacttcctat gctacactga agaggaatat gaaataggag agttgaagat
    54721 gcaagaatat cagtatccac ttgatttaga ttggacaaca gacgaaatgg tcattgtaat
    54781 gaagatgtgg gaagatctgg aacgtgcgaa tgaaaaaggg ataaacaatg aagctttttt
    54841 gaagacttat cagcagttta aaactgttgt caaatccatt ggtgaggaaa aacgattggg
    54901 acgggaattt gaaaaagctt ccggttattc tttatatcgt acagtgcagc aagcaaaaaa
    54961 aaatccaaac aaaactttga gaatgaacgg gtgagataaa tggaacagat gattgatcat
    55021 atcaagtcct ggcttgaaga agctggtgag aaaatcaaat cttctcaaca aacattaaca
    55081 atctcgcaaa aatcaaatcg aacggatcta gtaacaaatg tcgatcgaaa catccagaat
    55141 tttctaatcg aaaaaatcca ttcctttgat ccagaggcga aaatattggc agaagaagaa
    55201 gggtgtaatc aattatcgga tctcgatgga agagtcttta tcatcgatcc tattgatggc
    55261 accttgaatt ttgtgattga aggggaaaat ttttgtatta tgctcgctgt ttatgaatcc
    55321 ggcgttggaa agcttggttt catttatgac gtgatgagaa atgaactttt ttggggtgga
    55381 aaaggaatag gcgtgtataa aaatgatgag ccattgccta gaccagcaaa taaatcctta
    55441 tcggaaggct tacttggtgt gaatagttat cttttcggtc ataataaata tggaatccga
    55501 gaaattgcgg aaagcagcat ggggacacgt atgtacggat gcgctggtct tgaactagtg
    55561 gcaatcttga aaggaaacca cattgcttat atttcaaacc ttagcccttg ggattatgca
    55621 gcgggaaatg tcttattgga agagtttggt atggtaacaa gcggtctttt tggtactcct
    55681 ttgacatttg aaaaaaggga atactattta gcagggactt cttgtgcata tgcagaaatc
    55741 gcagaccttt tgaaaaaaga aggctgaaaa aaaggtagaa atcattcaca aaaatgataa
    55801 aaacgagcaa aagattaatt ttctcgaaaa aatgaaaaca ttttactata tttcatgaaa
    55861 aaagtctgct ataattagca gtcgagtaaa atttgccctg tcataaagaa ccaataaaaa
    55921 aggagttagt tacattgaat tatagaaacg atatccgtaa cgtcgcaatt attgcccacg
    55981 ttgaccacgg aaaaacaaca ttagttgatg aactattaaa acaatcagat acattagacg
    56041 cacatacgca attgcaagaa cgtgcgatgg actcaaatgc gctagaaaaa gaacgtggta
    56101 tcacgatttt agccaaaaac acagctgtag actataaagg tattcgcgta aacatcatgg
    56161 atactccagg acacgcggac ttcggtggcg aagtagaacg gatcatgaaa atggttgacg
    56221 gcgttgtgtt ggtcgtagat gcgtatgaag gaacaatgcc tcaaacacgt tttgtattga
    56281 aaaaagcact ggaacaacat atcacaccaa tcgttgtcgt aaacaagatt gacaaacctt
    56341 ctgctcgtcc tgagcatgtc gtagatgaag ttcttgaact attcatcgaa ttaggagcag
    56401 atgatgatca gttagacttt cctgtgattt atgcatctgc actaaatggt acgtcaagct
    56461 tgtcagatga tccagcagat caagaaccaa ccatggcacc tatttttgat acaattattg
    56521 aaaaaatccc tgctcctgtc gataacagcg acgaaccatt acaattccaa gtttcattac
    56581 ttgactacaa cgattatgta ggtcgtatcg gaatcggacg tgtatttaga ggaacaatca
    56641 aagtaggaga ccaagtagca ttaattaaat tagacggaac agttaagaaa ttccgtgtaa
    56701 cgaaattatt tggtttcttt ggactaaaac gtctagagat tcaagaagca aaagctggag
    56761 acttgattgc tgtctcaggt atggaagata tctttgtcgg tgaaacagtt actcctgtgg
    56821 atcatcaaga tgcgttacct atccttcaca ttgacgaacc aacattgcaa atgactttct
    56881 tagttaataa ttcaccattt gccggtcgag aaggtaaatt cgtaaccgct cgtaagattg
    56941 aagaacgttt gatggcagaa cttcaaacag atgtatcctt acgagttgaa ccaacaaact
    57001 ctccagatgc atggacagtt tctggtcgtg gagaattgca tttgtctatc ttgattgaaa
    57061 acatgcgccg tgagggatac gaattgcaag tatctcgtcc agaagttatt gaaaaagaaa
    57121 tcgacggtgt aaaatgcgaa ccgtttgaac gcgtgcaaat cgatacacca gaagaatata
    57181 tgggtagtgt tatcgagtcc ttgagcttac gtaaaggtga aatgcaagat atggtccata
    57241 caggaaacgg acaaatccgt ttgacattct taacacctgc ccgcggtttg attggttatt
    57301 caactgaatt cctttcaatg acacgtggtt acggaatcat gaaccatact tttgaccaat
    57361 atctgccaat gcttcctggt caaattggcg gacgtcacca aggggcgctt gtttcgatcg
    57421 atacaggaaa agcaacgact tattctatca tgagtatcga agaacgcggt acagtcttcg
    57481 tagaaccagg tacagaagta tatgaaggaa tgattatcgg ggaaaacagc cgtgataatg
    57541 atttgactgt caacatcacg aaagcaaaac aaatgacaaa cgtacggtct gctactaaag
    57601 accaaacatc tgtcatcaaa aaaccaaaac aattgacgtt ggaagaatct ttggaattct
    57661 tgaatgatga tgaatattgc gaagtaacac cagaaagcat tcgcttgaga aaacaaattt
    57721 tagagaaaaa tgctcgtgaa aaagcatcta aaaagaaaaa ataatctgta aaaggatgaa
    57781 gagagaaacc agcttgttat aaaaaatagc tggtttcttt ttttgtccaa ctcttttctg
    57841 tggagaagtc atctttgtca atggacataa attcagaaaa tacgccgaaa gacgtttaaa
    57901 agacttttaa aaaacttatt tctagagagt ttttgtttca taataagata atgtttcacg
    57961 aaaggagatc aacttgtcct tcgaagaaaa tcgaagtaaa atggcaagag aaaggagcgg
    58021 gaagatgaac gacttattaa aacaatactt tggctatgat gagtttagac ctggtcaaaa
    58081 agaaattatc cagaaagtca ttgatcagga aaatgtatta ggaatcatgc ctaccggaag
    58141 tgggaaatca atctgttacc agcttccagc tttactatta gatgggctta ctgtggttgt
    58201 gtccccttta atctctttga tgaaggatca ggtggacgcg gcgaatcaat taggtatacc
    58261 cgccactttt atcaatagct cgttagatgg ttacgaaaca gctagacgct tccaagaaat
    58321 cgatagacag cagtaccgtt tactttatat cgctcctgaa cgttttatca tgccggattt
    58381 tatccaagca atgaagcgat ggaacgtccg tatgatcgct attgacgagg cacattgtat
    58441 ctctcagtgg gggcatgatt tccgcccaag ttatttacag atggcgaacc agctagatca
    58501 actgccaaat cgtcctgtaa ttgttgcttt gacagctaca gcgactgtgc aagtagctgc
    58561 tgacataaaa agacttttaa aaattccaga aaacaaccat attcagactg gttttgaacg
    58621 agaaaatcta cgatttcaag taattaaaga tcaaaaaaaa gaacaatatc taatcgaata
    58681 tttaaagatc aacaaaaatc aatctggtat catttatgca gcaacgagaa aagaagtaga
    58741 ccgtctctat catttgctta aaaaattcga tttttccgtg ggtagatatc atggtggtct
    58801 aaatgagaat gagcgaacag aaatgcaaga agccttttta tacgatcgct tgcagctgat
    58861 tgtagcgaca aatgcatttg gtatgggtat aaataaaagc aatgtccgtt ttgttatcca
    58921 ttatcaaatt cctggctctc tagaagcata ctatcaggaa gctggtcggg cgggaagaga
    58981 tggtctttcc agtgaagcca tcctgctttt ctctcctcaa gatatccaag tccaaaagtt
    59041 ttttatccag cagtcccaaa gagaagaagg gcaaaagcaa aaagaatatg aaaaattaaa
    59101 agcgatgaca gaatacgtgt atattgagtc ctgtcttcag caatacatcc taaactattt
    59161 tggcgagaca agcagtccgt gcaaccgttg tggtaactgt ttagatgaca gagaaatagt
    59221 agaagtaacg acagaagcac agatggttct ttcttgctta aaacgtatgg gtgagaacta
    59281 tggtaaacaa atgctgatga aagtcttagc aggatcgaaa gaacaaaagc tgcaagcttt
    59341 aggttttgga catttatcta cctatggact gatgaaaaac caatcgcaaa aagaaacgat
    59401 gcagttaatt gaatatttga tatcgaatgg ctatcttctg accatcaatg gtgagtatcc
    59461 tgttttgaaa gtaacagaaa gagggataca agtattgaaa ggacaagaat ctgtttatcg
    59521 aaaggaaccc aagaaagtcc agcagctatc ggatgaagaa accgatacac tatttgaagt
    59581 gctgcgggaa ctgcgaacgg atctagcatc agaagcaggc gttcccccgt atgtcgtatt
    59641 ttcagattcc acattgaaag aaatgagccg aatacgtcca tcaagcagat tggagatgct
    59701 tcagataaaa ggagttggcc aaagcaagct tgataaatat ggcgaagcct ttttatctcg
    59761 gataaaaaat gcggactcta acgttctgga taagtagaaa gaacgaatac gtaaaaatga
    59821 ataaaaacaa ctggttaaat ctgttttttt tgctccttat gaaaatcaaa tatgttataa
    59881 ttaaggaatt agaatgggag gtaagcacag atggattctt tgtcgaaaaa acttgcgatc
    59941 caagtattaa atgatgaagc agaacggatc aaacgattaa tccgaaatca aaacaacagt
    60001 ctctgtatct cacaatgcaa agccttcgaa gaagtggtag atacacagat gtacggcttt
    60061 tcccggcaag tcggttttgc tgtccgtata ggagtaatcg gaaagaacga gggccagctg
    60121 atgttaagtg agctagaacg agaattgaat cagttatata gtgaggttta ccaagaaatt
    60181 tatgataaaa aagaagttgg caaggaggaa tagacttgcc taagaaagtg aaaaaaaggc
    60241 atctattaga ctatagcatc ttgattccct atttaatttt atgtgtattg ggattgatca
    60301 tggtatatag ttctacgtcg tatctattat tagaaaacgg acaaaatccg tccgcatcag
    60361 tcattaacca gagtattttt tgggtgctta gcttgattgc tatcgcacta ctttataaaa
    60421 tgaaaacaga tgttttgaaa aaccagcgtt tgatcatggc agccatcgca gttttgacga
    60481 ttttgctgct gattgttgtg ttttttggta aggagatcaa tggggcgaaa ggttggctgc
    60541 aaattgcagg attctcgatc caacctgccg aatacctaaa aatcatttct atctggtacc
    60601 tgtctctgac tttatctaaa agacaaaaca gtgtacaaaa agattttctt gggactgtga
    60661 aacgtccact tgcaatggtt atcggactta ctgcattagt cgctattctt cccgattttg
    60721 gtaatgcggc agttatcttt ttgattattt tggttctgct tttagccagc ggagtcaatt
    60781 atgtgtatac tttgattgta ggagtaggag gcttttgtct aagtactttt acgatctggc
    60841 tgatcaatat cacaaacgga aagatcttac ccggacgttt acagtatatc tataatcgat
    60901 ttgctattta ccaaaatcct ttctcagacg aattaaataa agggcatcaa ctagtcaacg
    60961 gctactatgc catgttcaac ggaggactat ttggcagggg attaggtaac agtatccaga
    61021 aaaaaggatt tttacaagaa gcacaaaccg attttattta tgcaatcgta gtggaagaac
    61081 tgggagtgat tatggggatt ttgatattag cgttgctatt ctttatgatt gtgcgcattg
    61141 tccttgtagg tatccgttca aaagatccgt tcaattcgct tttgtgcatt gggatcggcg
    61201 caatgttttt gatccaagta tttgtcaatc ttggaggaat tactggcgtt attcctttga
    61261 cagggatcac gttcccattt ttaagtcaag gaggctccag tttgctgatg ctttcgattt
    61321 gtgtcggctt tgtcctcaac atcagtgcgg atgaaaaacg caagagctta ggtttataat
    61381 aaaaaaagat gtaggagtgg ttcgatgaaa aaagttttag ttgctaacag gggtgaaatc
    61441 gctgtacgtg tatttcgtgc ttgtacagaa ttaggaatta aaactgttgg aatctatgca
    61501 gaagaagatg aatattccgt acaccgtttc aaagcggatg aagcatattt agtaggacaa
    61561 ggaaaaaaac cgattgatgc gtatctagat attgaaggga tcatttctat cgcgaaagaa
    61621 tgcggagctg acgctattca tccgggttac ggtcttttgt cggaaaactt gaattttgcg
    61681 caacggtgcg aagaagaagg catcattttt gttggaccca aactgcatca tttagatatt
    61741 tttggagata aaatcaaagc aaaagctgca gctatcgaag cggggattgc ttcgattcca
    61801 ggcacagatg gaccaatcgc ttctatagac gatgccttgg agtttgcgaa acaatacggt
    61861 tatccgatta tgatcaaggc agctctaggc ggcggcggac gcggcatgcg tgtagctcac
    61921 gatgaaaaga gtgcaagaga gggctacgaa cgtgcgaaaa gcgaagcaaa agcagccttt
    61981 ggtagtgatg aagtgtatgt tgaaaaatac atcgctaatc ctaagcatat cgaagtacag
    62041 attctcgggg atacgcatgg aaacgtcatc catctttttg aaagagattg ttctgttcag
    62101 cgccgtcacc aaaaagtagt agaagtagcg ccttgtgtct ctatgaatga acagcaacgt
    62161 caaaaaatct gccaggcagc tgtccaattg atgaaatatg tcgggtatgt caacgcaggt
    62221 acagtagaat ttcttgttga aggagatgat ttttacttta tcgaagtcaa ccctcgcgtc
    62281 caagtggaac atacgatcac agaaatgatt acagatattg atatcgtaac aacgcaactg
    62341 ttgattgctc aaggtttgga tctgcataaa gaaatcggat tgcctcagca agaaggaatt
    62401 aaattaaatg gttcagccat tcaatgccga atcactacag aagacccgtt gaataacttt
    62461 ttaccagaca cagggaaaat cgatacgtat cgttcacctg gtggttttgg cgtacgtctg
    62521 gatgtcggaa atgcttacgc gggctatgta gtgacaccgt attttgattc attgctagta
    62581 aaagtatgta cgcatggtgc tacctttgaa acagccattc agaaaatgga acgttgcttg
    62641 aaagaattta gaatccgtgg agtgaaaaca aacattccat ttatgctcaa tgtcatcaca
    62701 catcctgaat tccaatcagg aaatgcaaaa acaaccttca ttgatagtac agcaacatta
    62761 tttgaatttc ctcgactacg agaccgcgga aacaaaacga tgaaatatat cggtgaaatt
    62821 actgtgaatg gttttccagg tatcgaaagt ggcgaaaaac cattttatga agaaccacgt
    62881 atgcctaaag atctaatcac aagaactgat tacgtaacgg ctaagaatgt attagatgcg
    62941 aagggtgccg atgctttggt cgaatggatc aaaggacagg aaaatttgtt gttgacggat
    63001 acgacattta gagacgccca tcaaagtctg ctagcaactc gtgttcggac aaaggatttc
    63061 aagcagattg cacgtttgac tggagaaggt cttcctgaac tcttttcaag tgagatgtgg
    63121 gggggagcaa catttgatgt ggcttaccgc tttttgaatg aagatccttg gcaacggttg
    63181 agaaaaattc gttctttaat gcctaatacg ttgctgcaaa tgcttttcag aggttcaaat
    63241 gccgttgggt attctaatta tcctgacaat gtattggtgg aatttgtcaa agaagcagca
    63301 gcgcaaggaa tcgatgtatt tcgaatcttt gatagtttga actggactcc acaaatggaa
    63361 aaaagtatcc aagctgtacg ggatactggt aaaatcgcag aggcagctat ttgctatact
    63421 ggcgatatca acgatccaag tcgggcaaaa tacaatgttc agtattataa agacatggca
    63481 aaggaactag aacaactggg tgcgcatatc attgcaatca aagatatggc tgggctgctt
    63541 aaaccgcagg cagcttatcg tttgattagt gaattgaaag aaacgacaga tctgccaatc
    63601 catctgcata ctcatgatac cagcgggaat ggaatcatca cttattctgc tgcttcaaaa
    63661 gcaggagtag acatcgttga cgtggcaatg agtgcaatga gtgggaatac tagtcagcct
    63721 agcatgagca gcttgtatta tgcactggtc aatggtccac ggctgccaga aatcacgatt
    63781 gaaaatgcac agaaattaaa ccattattgg gaagatgtgc gcatgtatta caaaccgttt
    63841 gaaaacggct tgaatgctcc tgaaacagaa gtatatatgc atgaaatgcc aggaggacag
    63901 tattcgaatc tacagcaaca ggcaaaagct gtcggattag gtcatcgctg ggatgaaatc
    63961 aaacaaatgt atcatactgt caacttgatg tttggcgata tcgttaaagt aactccatca
    64021 tctaaagtag ttggagatat ggcactattt atggtccaaa atgatcttac agaagaagat
    64081 atttatgaaa aaggcgaaac actaagtttc cctgaatctg ttgtgacttt cttccaagga
    64141 gaactagggc aacccgttgg cggatttcct aaaaaattgc aaaagattat tcttaaaggc
    64201 agacctgcat tgaatgaacg tccaggtctt ttggctgaat cagtcgactt caacgaagta
    64261 aaaaaagaat tggcagaaaa aattggctat gaaccaaaac aagacgaagt attaagctat
    64321 ttgatgtatc cgcaagtctt tttggactat caaaaagcat ataatcaatt tggcgatgtt
    64381 acattactgg acacaccaac atttttccaa ggtatacgtt tgggtgaaac aatcaatgta
    64441 caaatcgaac gcggaaaaac gcttatcatt cgtttagatg aaatcggaga acccgatatc
    64501 gaagggaatc gcgtactgtt cttcaatttg aatggacaaa gacgtgaaat cactatcaaa
    64561 gataattcga tcatcagtac ggtccaaacc cgattgaaag ctgaaccgac aaaccgagaa
    64621 caaattggag caacgatgtc tggttctgtt ttggatgtat tagtgaaaaa aggcgataac
    64681 gttaaaaaag gtgatacgtt gatgattact gaagcgatga aaatggaaac ggccatcgaa
    64741 gcacgttttg acggagaagt cgcacatgta tatgtgtctt caggagacac tatttcgtct
    64801 ggtgaccttt tgattgaagt gactgagaaa taataagcga aaggtgggga aacatgaaaa
    64861 gactgggttt gttttggctg attctgctat tagttattgt ggcattctac atggaaccag
    64921 tcttgtttcc gccaaaactt gaagtgaagg aaaactctga tcaacaaata tcaaaccaaa
    64981 tgacaacgtg gaaataccag gagcttaaag caactggttt ttctacttat atcggaaaac
    65041 cgatcgatca gctggaaaag gattttggcc aagcctatga tcgattaact agcggatttg
    65101 gttttgaaac aagatattat gaaaataaag ctagtcatct cacatttgaa gcgaacatcc
    65161 aagacagcag agtcacaact gttaaagtac tgcaaacagg gcctgctgat atcgcgccgt
    65221 tttatttagg gatgacgatg caagatctta cgaaaatcac tactatctat actaatttca
    65281 cttttgagta ccatgataca gaagttggaa tcgaactaat ggaagaggat atgaattatc
    65341 gtccgctaat tgcttttgat aacgacactt ttgctatttt attttttgat caaacaacaa
    65401 acggcctatt ttcagttgtg tatttagata aagatagtct tttgaaacta ttgccatatc
    65461 aagtgtttgg tgaaggcctt ccacattatc aagcagataa atcggctgat tgggaatcaa
    65521 tcaatcgcgt taaagaacga aaaagtacga ctttattaaa tatgcttaga agagaagacg
    65581 aacttcccat atacaatcaa acacttgcct ttcaaaacca cagtcagctg ctactacatg
    65641 attttttgac aaggcctgag gaaatattgt cagaggaacg tatggctgat tggcaaaaat
    65701 cgctaggcag tgctcaaacg acagtgaaat tctcactgac gaatgatgaa ttggagaagt
    65761 taatcagtaa acaaaaatta gaaaatacta gtgggctatt tattcatccg gcgattgacg
    65821 ctactttttc gtttttatat tggtacagcg atccttacaa ccatgaccgt ttcatggacc
    65881 cgggaacgga ttctgtaggc attgcttttt ctaaagaaaa tatgttagtc ttattgcaag
    65941 aagaaaacgg agaaagtagt gatagcagtg atcgttaacg aagagctgtt tcaactggag
    66001 gatcaatgcc tccaagtcgc tgaaatgata aaaaagagta aaacgatggc ttcttatctt
    66061 gaacataaac agtcaatgga agaatctgca aaagtttgcc agttgaaaga agcgttcttg
    66121 tctaagaaag aagcatttga aaatgtagcg gcatatggtg agtatgcacc tgattatcgt
    66181 gaaaaaaaac gagctgttcg aaaagcaaaa agacagcttg atatggatga gcatgttgca
    66241 gctttccgat atagtgaaac acagctgcaa agtctgttgg atcaaattgt ccaagtactt
    66301 gccgaagaag tttctaatga aatcaaagta gatgcaggta gcccgttttt tgaaacgaaa
    66361 aaacactttg gatgcggagg taattgtcat gcaattagac aatagtgaat ttgaaataac
    66421 aaaacgacgc gggctgatcg tatgggtcta cagcttaaaa caattaaaga atctgaaaaa
    66481 gttcggcttg ttgcattatg tctcaagaag aatgaaatat gtcgtgcttt acttaaatga
    66541 agagacattg gaagaaacag aagaacgaat ccgtaaatta cattttgttc gaaacgtaga
    66601 acgttcttac cgaccggata tcgaaatgaa ttttgccgaa aaaataggaa acaaaacagt
    66661 attaaaagac gaaggtttcg aaattgaaga gctaaataca gaaatccgat tagctgaaca
    66721 tctttaaaaa tctcttatga gcagttttta aataaaaaat aacttggata acgatcgatt
    66781 tttgatcatt gtccaagtat ttttttggta tactagtacc agtaccattt ctaaggagtg
    66841 agtagatgcg gataatatca ggaaattatg gcgggcgccg tttaaaaagt ttagcagggg
    66901 cgaacaccag accaactaca gataaagtaa aagaatccat attcaatatg attggaccat
    66961 attttgatgg agagacagta ttggatctgt ttgcaggaag cggtggttta gctatcgaag
    67021 cagtatctag aggctgcagt catgcggtat gcgtagacaa aaattaccaa gcgctaaaaa
    67081 tcatcaaaga aaacatcgaa attacgaaag aaccagagaa atttaccaca ataaaacttg
    67141 atgcggacaa agcaatcgaa cggctagcag cggagaaaca acaattcgac tacttgtttc
    67201 ttgatccgcc atatgcaaaa caaaaaataa tcgatcaaat ccataaaatg gaagaactgg
    67261 gacttttttc taaaaccgca gttatcgtat gcgaaacgga taaaacagtc gaattgccag
    67321 aaactgtggc tggattccat caaataagaa aacagattta tggcataacg gccgtaacta
    67381 tctatagaaa agagggaaat caatgaaacg tgcattattc ccaggaagtt ttgatccttt
    67441 tacaaaaggt cacttagata cggtggaacg tgcggctaaa ttattcgatg aggtagtaat
    67501 tggtgttttt atcaatactt caaagaaaag tttgtttccc ccagaagaaa gaatgacatt
    67561 gatcacaaaa gctgtttctc atcttcctaa tgtaaaagtc atgcatcaag aaaatcaatt
    67621 gacggtagaa acagcaaaag agattggtgc agatgcgttg atcagaggca tacgaagtat
    67681 caaagacttt gaatatgaac gagagattgc tcagatgaat catcatctat atgatgaatt
    67741 ggaaactgtc ttcttattag caaaaccaga atatagtcac gtgagttcca gtattttaaa
    67801 agaagtactg cactttggcg gagatgtgag cagctactta ccgccagtga tcaacgaagc
    67861 tttagctgga aagcgtgaat caaatgaaag ctaaacaatg gttgaaaaca gtactgatta
    67921 tcatatttgg aatgttgatc attggatttg tagtagttcc cttgccgtat tatgtagaat
    67981 caccgggagc cacgatcgat ctgaaagaac taattacggt caatgataag gaagataaag
    68041 gttctgggtc tttctctctt acctctgttg gtatcaggca agctacaggt ttcttagctt
    68101 taaaagctaa aatgacccct tttgaagaat tgatcagtga agaagaattg actggtgggg
    68161 cgacaaatga agaatataat caaatgcaac agtattatat ggattcttcc caaaatgcag
    68221 caatcgaaca agcgttaaaa cttgcagaca agccttataa aatggaattc aaaggcgtat
    68281 atgtcatgag tgtagagaaa acatcgaatt tctttggcaa gctttcagtt ggagatacag
    68341 taacaaaagt agacgggaaa agctttcaaa gtacagaagc atttatggat tatgtaaaaa
    68401 gccaaaaagt tggacaaaca atcgaaatca gttatttgca taatggtgaa gaaaaaacag
    68461 cttctggtga tctgatcgag ttaccaacag ataaaaaggc aggaataggt atcacgctta
    68521 ctgaccatac cgagatcgaa tcagatacag atgttcgtat taattctggc tctatcggtg
    68581 ggccatcagc gggattgatg ttcactttag aaatctatga acaagtcact ggtaaaaact
    68641 tgcgacatgg taagcaaatt gcaggaactg gaacgatcaa cagtgaagga gaagttggcc
    68701 gaatcggagg aatcgataaa aaagtggcaa gtgcggataa agctggcgta gagattttct
    68761 ttgcaccaga tgatacgatt tcagacgatg ttaagaaaga atatcctgaa ataaaaacca
    68821 actacgaaga agcaaaagct gccgctaaaa aattgaattc ctcaatgaaa atcgtaccag
    68881 taaaaacagt acaagaagcg cttgactatc tagagaaaat gaaatgaaac taaataatta
    68941 aagaggggtt gtgacacgag ttctgtcaca acccctcttt ttcgtcaaaa atcttcacga
    69001 taaaaataaa aacaaaagaa aaaattgacg taattagatg ttgaagggac gattttgcca
    69061 gagctcactg tttcttcaat tttaaatgaa aggagtaatg aatgattttt actggtcatt
    69121 ctttgaaaaa agaacaatga tagaaaaaat cagcaagaaa atactagctt cacccaaatt
    69181 gatcatttgg atgtctatga tagttcttat cttttgtatc gcaagtggtt ttttattatc
    69241 aaatttgcta ttttatagag aaacagaaga gactgctgca aaagaaatac tttcttcgtt
    69301 tagttccagt ggagaagatc catcagctga aggaaacgat gtagaagagg atgctcgtcc
    69361 aaaggtcatg tacaccgata tcaaaggaag tgtgaaggag cctggtatct attccttttc
    69421 ttcagaagaa cgggtctatg atgtactaaa gcgtgcaggt ggattattag aagaagcgga
    69481 tagcgatcga atcaactttt ctgcgaagat agaagatcag caagtcctat atatccctgc
    69541 tgtaggtgaa gagctgccag aacatcttga tcagttggca tcctcggaag gaaaacagcc
    69601 tacagcagat tccgagcctc ccaaaataaa tatcaataca gccactccat cagaacttca
    69661 gcagattcct gggatcggat cagtcaaagc gcaagaaatc attcgattta gagaagaaaa
    69721 cggatccttc cagaaagtgg aagacctgca ggagatttct ggtatcggtg aaaagacagt
    69781 tgaaaaacta aaaaacttcg ttacaattaa atagaatgat tcaaaatcga ctggcacgag
    69841 caataaatgg acgctaatgg atactaagaa taatccaatt ctaagagctt ggcaggacga
    69901 ggaggtagta tttttggata ggaaatagct tgattgttcg caaagaaaca ttaaaaaaac
    69961 caatgctgaa tgtctatctc caaaataaaa tatctgggat tcatattatg aatacggctg
    70021 tcagcggcaa taacagtcaa gctctacgag aacgctttgc caaagatgta cttagctata
    70081 cagcagataa agtatttatt ctcattggga cgaatgatct agcagagcat aaacaacttt
    70141 ctaaagaaac gtaccaaaaa atctgcagtg gatgatagtt cagctgaaaa aagactatag
    70201 ttctgatcat gctttcttta tcacgccacc agcagtcgat gagacaaaac aaaaatatcg
    70261 gaataacaag ttgatcaaag aatatatctc tgttctcaca gaagtagcaa aacgccatga
    70321 ttgtgaagta tcgattttta tacggaattt cttgaacaaa tggattcgaa gaatttttat
    70381 aatgggctaa tggatgacgg acttcatttc ggcagtgaag ggtaggatct tttgtcagac
    70441 aggatgattc gttatattta aagaatattt tgtttaagca atgagtactt tttaatcaac
    70501 ttgaaaaaac ggaggaatat aaaacatgtt agaaaaatct tcaaaagcat gcgatacgaa
    70561 taaagaaaaa gttactgata agtcacataa tgaacgcatt ccttgggacc agtactttat
    70621 ggctcaggca gtactgttat ctttacgtag tacgtgtaca cgtttagaag taggagcgac
    70681 actcgttcga gaaaaaagga tcattgctgg cggctataat ggagcagtca gtggagatgt
    70741 ccactgcata gatgaagggt gttacgtcgt ggatggacac tgcttgcgaa cgatccatgc
    70801 agagatgaat gcactcctac agtgtgcaaa acttggtatc ccgacggaag gttcagaaat
    70861 ctatgtcaca cattttccat gtttggcctg tacaaaggct ttgttgcaag ctggtgtgaa
    70921 agggatcaat tatctccatg actatcgaaa tgatccttat gcccaagcgt tgatcgaaca
    70981 attaggtgta tctgtacacc aagttgcttt agactcacag catttttcaa aacttcaaaa
    71041 tgaattaaca ggaaaacatg tctagcgttt tagaaaggca tgttcgaaat cggttgattt
    71101 ttccggcaat tacgtcgatg attatctgtt tgttgtatta cactgacaat tggggttatc
    71161 gtttgcttct tgccggaatt tttttatggt tttcgctaaa agaaggacgt tttatcgcgt
    71221 acttgtgtat tttgtgtagc ataacggtat ccatttctta taggctacaa gagtattcat
    71281 ttttagagga aaaaacaaca tctgcgcaaa ttactgtatt tacagatacg attcgtgcaa
    71341 atggtaattt tttgacaatg gaaggaaggt tatcagagaa taaacaaaag ctccagcttt
    71401 cttatcaagt aaacacagaa gcagaattga aaacatggct taacttccga ggaaagggaa
    71461 tagaattgac tgctgaaggc gagttcatct ctccagcaaa aaagcggaat ctttataatt
    71521 ttgaccaaga agcttacttc aggaaccata gaatttctgg acggttccaa attcaaaaga
    71581 ttgaacagat caccatgcaa aatcactggc gaaactggct tcagagaaaa agaggatctt
    71641 ttatctcctt tgtccaatct gaatttccgc aaaaaacaag tgtatatatt aattctttat
    71701 tatggggcta taaagatgca ggattcagag aaccagaaga aatttttagg gagagtggtt
    71761 tgctgcatct gttcagtcta tcgggtctac acatccaatt ttatttaggg tggctgtatt
    71821 atttgtttcg acgtatcgga tggccactac acgtcagtat tattccgttg agtctactaa
    71881 ctatctgtta tgtttctatt gcaggaagtt ctatttctgt tttgcgtgct agtttgctgt
    71941 ttttattgcg attgctagtc aaattgctga ataagcatta ttccaccatg gacttatttg
    72001 cagttgtctt ttggcttctt ttactatttg atcctcgatt tctttttcat gcgggtggac
    72061 agcttagttt tttcatgagt tttttgttta tcctgatttc ttttgatgga gattggttga
    72121 aaaaaacggc ctctcacgtc ctgtttacta tgatcacgat gccgttgatt gtatggcatt
    72181 tttatgagtg gcctatttta ggtagtcttt ttacattact gattgcaccg gtattcaagt
    72241 ttctttttct tcctggtgtg ttatttctca cactcttcaa tcgctggctg ccggaaactt
    72301 tacttttgct gatagaagag ggattaatct tatttgagcg aataatcgat ttttcttcag
    72361 ggtcgtctct cattatagga cgtttgcccc ttgtgctatc tgggatgtat attttcggat
    72421 tactgatttg tatggatagg ttgaaagaac aacctgtgaa acacttgttt tatgttggtc
    72481 ttttttcttt tatttttttg actttgccat ttttacgctt ttcttcaacg atcgctttta
    72541 tcgatgtcgg tcaaggagac agtatctttt tgcaaagtcc ttttcgaaaa gaaacgattt
    72601 tgatcgatac tggaggtcag ttacactttg aaagagaaaa gtgggcgcaa ggtatgatac
    72661 gtcctcctgc tgaaagaaat atcgttccat atctaaaagg tcaggggata agtgtaatcg
    72721 ataaactcat cttgacacac gacgatacgg atcatgtggg agaattaccc acgttatctc
    72781 agcattttac tatcaaaaaa atttatatcg gttggggcgc tggacgaaat gagccattac
    72841 aaaggcattt atctgaagct caaaaaaatg gtactgagat cattgaaatc aaacatgggg
    72901 acaggatcag cggttattat gatctttatg tattgactcc ttttgaaaag ggagagggaa
    72961 gaaatgaaga ttcgattggt ctatggatgg aatataacaa taggcgcttt ttatttttag
    73021 gagatttgaa tcaagcaatg gaaaaacaat tgcttttgat ttatcctaat ctgaaagccg
    73081 atgtagtcaa attaggtcat cacggtagcc gtacgtcaag taacacagat tttctttccc
    73141 atattgaagc aaaacatggg attatatcct gcggcgtaaa taatcgttat ggtcacccgc
    73201 acagcgaagt attggagaca ctagaagaaa atcagataaa aacatggcga acggatcaac
    73261 aaggaatgat cacctatcgc tggcatccag tttttcatcc tcatgggcta gtggaaacaa
    73321 tgatagacta gtaattctca tctgctcatg gtaggataat ttttgaaagt ggtgagtaat
    73381 ttgagtatac aagcagagtt acaaaaaata cgtaaagaaa aacttgcatc ttgttacttg
    73441 attttaggaa cagaaaagtt tctccaagat caagttcgga cagaaattgt caaaaaaatc
    73501 caattagagg gcgaagatga cttaaatttt ttaagttttg acatggaaaa tgcaagttta
    73561 gatgaggtag tagctgaagc agagacgttg ccgtttttcg gagatcaacg gttagtattc
    73621 gtagagaatc cttatttttt aacaggtgaa aaagtaaaca atggaatcga acaaaatact
    73681 gatttattga cggcttattt gaaagaacca ttagaatcga ctgtattagt attctttgcg
    73741 ccatatgaaa agttggatga acggaaaaaa gtaacgaaac aattgaaaaa aacagcaatt
    73801 atcatcaatg tccaacagtt gaatgaaaaa gaagtacgtc aatatctgat gaatacctta
    73861 gagaattcct caatcaaaat ggaacgaagt gcaattgatt tattcttgag gttgaccgac
    73921 ttagatttat ccaaaatgat gagagagtta cagaaattgg tcctttatgg acaaaatcaa
    73981 cagcaaatca cggtaagaga agtagaagaa ttagttccta aaacgttaga acataatatt
    74041 tttgacatga cccaatatat tttaaaaggg aagacggaac aagctttgcg tttatacgaa
    74101 gatttagtta tgcaagggga agaaacaatc aaaattaatg cgattttgct ttctcaatta
    74161 cgtttatttt tacagacaaa atttcttgta aagattggtt atcagcaggc aaatattgct
    74221 gaaacattga aaatccatcc atatcgtgta aaacttgcca tgcaggaagt aaaaaaattc
    74281 gatgaacatt tgctggtaca gttgtttgat caattagttg agatggatta tcaaatcaaa
    74341 acgggacaaa tcgaaaaaga attaagtttt caactattcg ttttgcgcac agggcagttg
    74401 ttaagaaatc gataagaaga aagacgaggg caaagcatgc gggaaggtcg tttgtttttg
    74461 tccttttttt gacaaataaa aaaatcggcc gaagccgatt cttttattta gcgatttttt
    74521 tgcttaaacg agatttgtcg cggttagctt tgtttttgtg gattagacct tttgattcag
    74581 ccatatcaat agctttaaca gcttctttat ataacgcatc tacgttgtca gcacctgaag
    74641 ctacagcatc ttcaaatttt ttgattgcag tacgcatagc gcttgtttga gatgaatttt
    74701 tcacattagc gttttcgctt gtacgaacac gtttgattgc agattcaatg tttggcatta
    74761 gtttcacctc cgataactta agttcttacg cgtgttaccg cataattcaa cattcattat
    74821 tatacctaaa ggcagcgtgc tttgcaatat gaacatgaca agtttttttc cttaacagtc
    74881 ttttattagg attttttttc agtaaaaacg gatagtacaa gctgaaaaaa atcaaaaaga
    74941 cgctattgtg ggaggcaata gcgtcaaacc aaactagatt tttatttatc tatttaaaca
    75001 aagtttgaat gggaatgttt ggtactaagt tattatataa caaagagaac cgtttgcaaa
    75061 gttttttttg aaaagggata cgattccctg ttgttctttg tttttctatt aagaaactgc
    75121 agttatttta taaccagtat cctttgatca gtaaaggcta ttctggtgta ccgattattt
    75181 taatgtattc atcgatattt tttatcaaca ttttttttat gaccaactgg ttccgacggt
    75241 tccatttgcc acttacttcc agcacatatt tatttagggg caaacgtaag atatattttg
    75301 ccaaatagcg atctttaagc aggccattga tcacacggtc ctcaagctgc aagttgatcc
    75361 cagtcagcat cattggctgt tcttgtaaaa cgtacgtatc aattaaaaga ccttcaaaag
    75421 tttccacaag cgtcttcctt tcttttcaaa gtaacctgaa aacaggcact aattcttcca
    75481 ttttgatatt cgttgaagtg gatgcgatca ttctttcttt tgtccactgt aatctagtat
    75541 aacaaaaaag agcagaagag ccaaaaagaa aaaagagcat cgaattctat aggaagtctc
    75601 attggcacgg cctaaattat tacaaaacat tgattaaaaa aagcccctgc atcgcaggag
    75661 catcccctat atcgttttaa taggtcaatc aaaaagcagt atcaaacaca ttttgtatca
    75721 aatcaggaaa taatagataa gctaagccca gaatcaaaag taccgctaga agaaaccagc
    75781 cgattgttcc tatgaaatac tttaattttt cgaacattgt atcacctcgt tgtcagtata
    75841 tcacggatca gtaaattggg ggtgttaaga atctcctaaa atagacaaaa tttgttctat
    75901 tttcctaaag caaatacttg taagatacag taagtgatac cagaagcaat gaccggtccg
    75961 gcggcgattc ctcttaagaa gacaacacct aaaatcgtgc cgaaaacaag tgcaacagtg
    76021 atttgtggat cagaagcaat caatcctaca cccttggaag ataagacagc cactagccca
    76081 ccgcaaaaaa cagctaccca gccaataggg gatttaaagg cttctaatag atcacgtaga
    76141 ccgatttctc ctgttgcgat agggattaga atagccgctg tgatgatcgt caccccaata
    76201 ttgattcctt tgccttgaag ccaagggaaa aaggaacggg aggctggtat gagcttcata
    76261 atcaaaacaa aagctgccgc tatcatcaga ctttgatttt tagctaaaat tgctacaagt
    76321 aaaataattc ctaaaaaaag ccaactttcc atgaaatata ttcctcactt tcttcgaaac
    76381 aatcataaca tgtttttaga aagttacaaa agtaggaatt catccttcaa gacctattca
    76441 taagctgttt ttttcataaa ataaacaaaa tcataaaaaa acactttgct tatttgacag
    76501 aagacagccg cgctttgtat agtggacaag acttacattt ttttgaagaa tcagaaagat
    76561 caggtaaagg tcttagtaaa cgcaagccat tcagaataac caatattgtg cttccttcgt
    76621 gtcctacaac tccaagaggt agatttaaaa attgcaggaa gttagaagca atcaacaaga
    76681 gaataacaag aatcgaaaaa ataatatttt gtttgatgat ccgccgcatt tttaaagata
    76741 gccgatgact gtagacaaat ttatttaagt cgcttttcat taagacgatg tctgcgatat
    76801 ccatagcggc atctgtccct tgccccatag cgacacctaa agaagcggct gctaaagcag
    76861 gcgcatcatt gactccatca ccaaccatcg catttacttg gtaaagttca ttctcttttt
    76921 tgactagttg tgttttttct tccggagtac agcttgcata gtaatgttca atccctactt
    76981 gttcagcaat ggcctttgct gtgccagaat ggtcgccggt tatcatactt gtatggatgt
    77041 tttgggattt aaagtaggaa attacttgtt gggtatttgc ttttggaata tctagcagac
    77101 ctaaaacagc aattaactgc tgatctttag aaagataaat cacggttttg ccttgatttt
    77161 ccaaacgttc gatcatttcc gcaatctctt tgctgattat catcgtctca ggatcatatg
    77221 cgtgcttgcc aactttccat tgcgcaccta aataggtagt ttgtaatcca aaaccagtaa
    77281 tttcttctat tggtaagtat tggatttctt caggtattgt gcaatcgaaa tattgcaaaa
    77341 tcgcatgagc aagtggatgc gtcgtttttt gttccatagc aacaagaagt tgttgtgcca
    77401 aatccttttc atcaaagaaa aagctgtcag ttacaactgg ttttccttta gtgagcgttc
    77461 ctgttttatc aaaggcaatc gcttttaatt cagaaagctt ttctaaatgg ataccgcctt
    77521 tgattaaaat cccatttttt gcagaatttg aaagagcagc tagagaagct ggtgtagcag
    77581 atgcgacaag cgcacaagga gaagccacaa ctaataatac cattcctcga taaaagcttt
    77641 catcccaact ccaacctagg aaaaagtggg ggagaaggat cattagagga acagcaagca
    77701 aaatcaattt tacataatta ttttcgattc gttcgataaa tgaagctgtt tgagttggcg
    77761 tattctgcgc ttcttctact aattggataa tcttagcaaa gacagtttcg gaactcgttt
    77821 ttgttactcg aatcgtgatg ggatttcctt gattcagcgt tcctgcatac atctcatcgc
    77881 ctaaatattt ttctacaggc acagattcac cgcttaatgc agactcatcg atcgttgcct
    77941 gtgtgctttc taaaaagcca tctatcggaa cagctgctcc tttagcgaca aataccaagt
    78001 tatccacctt tagttgagaa acatctactt cttgcatttg tccattttct tttaataatt
    78061 gggctttttg tggttgaaga ttcatcaaag cagtaatttc tttttgactt ttattagttg
    78121 tgtattcctc taatgcaccg cttaaacaaa agatgaatgt caacattgct ccttcaaagt
    78181 aattaccgat caaacaggca ccaatagcag ctaaagccat caataaatcc acattcagtg
    78241 tccgatcatt ccacaattct ttcaagcctt ccgatgtttg tttatatcca ccgatgataa
    78301 tggcactgat ataaaaaagt ggggtgatgg taagagagaa tcggtcgaag ataaaaccga
    78361 agatcataaa taaaaggcag ccgattgttg ctgcaaaagc ttttttctga ttagtcatcg
    78421 ttattagacc tccttgtcaa aacaaggata gcataataaa aatgtaattg ataataataa
    78481 cagctaaatg agaacgataa tggttatcat ttggtgatta agcttgatgt tgtttttatt
    78541 atttataatg attattatta aagaaaataa aaaaccagaa catttctcaa ataagagaag
    78601 tgttctggtt ttttctacat tgcaataaac caataaccaa tcaaaatgat accaaggata
    78661 atacgatacc agccaaaagc ggtaaagtcg tttttcttca aatagcttag taagaatttg
    78721 atagctaaga cggaaaccac aaaagatacg aatgttccta caagaagaac aacagtttct
    78781 tccattttga atgaattccc ttcagctaaa tatttgacga tcttcaagcc gcttgcgcca
    78841 aacatgacag gaatccctaa gaaaaatgaa aactctgtag cgacaaaacg cgaagcacca
    78901 atcaagatag atcctaggat cgttgcgcca gaacgggatg ttccgggaac aagtgccaag
    78961 acttggaata acccaacaag aagagctgct tggtacgtaa agtcattcag agaagtccaa
    79021 cgaggtgttt tgtttttgtt gcgtttttcg acaataataa aggcaatacc gtaaacgatc
    79081 aaaacaatgg caactggtaa gaacttgtgg aaatttgctt ctaaccaatc atccaaaggc
    79141 aaaccaatga tgatggctgg tatgcaagca acgatcactt taaaccaaag tgtccacgta
    79201 tctttttttt ctaccgttga tttacttgga gaaaatgggt ttaacttgtg aaaataaaga
    79261 acgacgacag ccaagatcgc ccctaattgg ataacgacat tgaacatcga cataaattgt
    79321 gaactggcat ccagtttgat gaattcatct gctaggatca aatgaccagt actactgatg
    79381 ggcagccatt ccgttattcc ttcaataata ccgagaatca ctgctttgat aatatttgca
    79441 aaaaacataa attccttcct tcccaattaa gatacatctt atagtatacc gttatttttt
    79501 gagaaaccca atctgttttt taatattaag aaaaacttga gaaataaagc agataagtac
    79561 acgaagagaa aaaagaagac aaagccctcg ttcagacttt gccttttatg attctctggt
    79621 aaaaattaaa atatccccat tatagaaacg agtcgcgact atgtgttttc ccgttatcga
    79681 tataagacgt atcattgatg ccgtggatag aaaatcgacc gtttgcataa gtgacctttg
    79741 ttacgctgcc atttaaaagc ccagcacgaa caggctgttt aggatcgatc agattaagca
    79801 aaaaggcgat cgtcaaacca tgagatacga ctaaaacatt tccaccacca tttttttcgc
    79861 agtgatgggc gatatcttca aatcctgtcc atacacggtc tcgcaatgtt tcataagttt
    79921 ccgcccaccc agcggtatct aagttgtata cagcattagc aatttgttca aaagaaactt
    79981 ctgtggtaaa catttcatca tatgttttaa aattcaatac acgagggatc acaccccaca
    80041 tttccatgtc atatccacct tcaagagacc cgaaacacca ttctctaatc cttttttcaa
    80101 taaaataagg aatttctttt cccttagaat gttctcctag aataatacgg gcagtttcga
    80161 ttgcacgacc actgtcacta gaataagcaa atgaaaagtc gacatttttt aacccgcgac
    80221 ctaaataatg aatgccttct tgtccttgct ttgtgagggg tgtatcacac cagccttgta
    80281 ctcgttcaat tgtattgaac atcgtttttc cgtgtcgtac gatataaagt gtagtttctg
    80341 tcattttatt ctcctcctaa gtcgttttaa cgattgaaaa aaggatttgt ccttttttcc
    80401 tgttcaatcg tcgttgcatc gccatgtcct ggatagactg caaattcatc aggtaataca
    80461 aacagctggg tccgaatact atgaagtaat tgttctaaat tccctgtata cagatcggtt
    80521 ctaccgatac ttcctctaaa cagggcgtcg ccagaaacga caaaatcatc aaaaataaag
    80581 ctgacgcttc ctatagaatg ccctggggta gggacgacgc gaaaagacat gtttcctaaa
    80641 gtataagttt tcatttcaaa ttcatattct gcaggcgaga caataacatc agcaatatca
    80701 tcatgtctac cgagtccaga aagattcaaa atcggatcac ctagccattt ttgctctagt
    80761 gggctgacat aaactgggat ttgataatac gcgcgtaaag gttccactgc accgatatga
    80821 tcgtagtgag tatgggtaag caaaatcgct accggctgtt ggtttgtttt tttgatttct
    80881 tgtttgattc gttccgcatc ttctccaggg tcaatgatca aaagtgcttc ttcgttgtag
    80941 accaaataac agttttcttc aatcattcct gtttttaatc tttcgatatg catgtgcatt
    81001 cctccttgat agccaaaact tctttcatcc attagtataa cgcattcatt gctaggaaac
    81061 aaaaacaggt acttatttct ctttacttat ctgaattatc agactatatg aaaagtattt
    81121 ggatattcta aagagaagga aagtaagttt tcatagcatt ttaatatgtc cttgttacat
    81181 tagattcatc caaaaatcca aattctatat cctatatccc tgcctaatca gcagggtgtt
    81241 tttttatgtt tggaaagaga gctctttttg ctaaactagg ttttttcagg taatcttaga
    81301 gagaaagagg tggtggaaat gatcaaacag tcaaaaatat ctgtgcggca cttagtagaa
    81361 tttattttgc gacgtggaag tatcgacaat cgtaaaaaaa gtaaccatac tgcattagaa
    81421 ggagcgagaa tccaccgcaa gctccaaaaa gatgcgggag aaaactatga aaaagaagtc
    81481 tttttaaaaa caacagttca attagatgaa tattacctga tcgttgaagg ccgtgcagac
    81541 ggtattttca aaagagacgg tatttattat atagatgaaa tcaaaacctc cgaaccacga
    81601 tttgaagatt tagaaccaga acaagtggaa cttttctttc atcaagcaag ggtgtatgcc
    81661 tatatctata gtcaagaaca tgatttacaa gaaataaatc tgcaattgac ttacttccag
    81721 acggcagaag aagtgatcac gagaaaggtt gaacatcaga caagagagca gttagaaact
    81781 ttttttaaaa agctgactga agattataaa gaatggcttg tttttcaaga aaactggcgc
    81841 actgtacgca atgcctcttt gatggctttg aaattccccc atgatgagta taggaaaggt
    81901 cagcgtgaac tagcggtagc tgcttataaa acgatccgta cgaaacagaa attgtttgta
    81961 gaagcaccta ccggaacagg aaaaacaatc tctacgttat tccccgcttt gaaagctgta
    82021 ggggaagaag agggagaaaa gatcttttat ctaacggcta aaacaataac tagacaagta
    82081 gctgaagatg ctatgacagc attaaaagat acaggagctg aagtaaaaag tgtcactttg
    82141 acggcgaaag acaagatctg ctttttagat gagacgacct gtaatccaga tcagtgccca
    82201 tatgccaatg gttattacaa tcggattaat gaaggtttat gggatctttt gaatcatgag
    82261 aatcagatca ctcgtgaagt catcgaaact tatgcaagaa agcatacact ttgtcctttc
    82321 gaactatcat tagatgtcag tatctggtgt gacgtaatca ttggggatta caattattta
    82381 tttgatccaa ctgtttattt aagacgtttt tttgaagatg aaaaaaacga ggactatctg
    82441 tttttgattg acgaagcaca taatttggtg aatcgttccc gagagatgta ttcggcagaa
    82501 ctatcttatg aaaaaacgaa acgaagtaag gaagctatac caaaggaatt caaaaaactt
    82561 catcgccgtt tcaacaaact attaaaagaa tttgattcga tccgagaaat agcaaaagaa
    82621 gatcattggg attatcatca tcaaaaagca ccggctgaat ctttagtaaa ggcaggttat
    82681 caattaagcg aaaaaattaa agaatggctg gcagaatttc ctgagcaccc atcacaagaa
    82741 caattgcttc cttattattt tgatttgctt cattttttga aggtcagtga attttatgat
    82801 gatcactacg aaacaacagt cgaaaaaacg tatcgcgatc tgatagtaaa agagttttgt
    82861 attgatccaa gcttgtttct tgagcagtcg ttggataaag gaaaaagcag tattcttttt
    82921 tctgctagtt tttcaccact ctcttattat caggaaacac tggggggaca aaaaagtctg
    82981 gcttacaaac tgccgagtcc tttcccagaa ggaaaccagc aagttttcat cgcaaattac
    83041 ctagagacga cttatcgaaa aagggaacac agtctggcaa aattagtaga gacgattcat
    83101 gcttttgctg atggaaaggt cgggaattat ttcgttttct ttccttctta tcaatattta
    83161 gatcttgcgg tggaagcatt cagacagcaa tatcccgaca gcaatgtgct aatccaagaa
    83221 acggacatga atgaggaaga acgcgaacga tttttaacaa aatttcaaac aaatcccgct
    83281 gaaacattga ttggattttg cgtacttggc gggatttttt cagaaggaat cgatttgaga
    83341 ggggaccgat tgatcggcag tatgatcgta ggtgtaggtt tgccgcagat gaatcatgag
    83401 caggaactga tcaaatcata ttatgatgag aaggaacacc ttggatttgc ttacgcttat
    83461 cagcttcctg gaatgaacaa agtcttgcaa gctggtggtc gagtgattcg tggcatggcg
    83521 gatcaaggaa tcgttgtatt ggcagatcaa cgattttcta gtttttctta tcgacgttta
    83581 ttcccacaac attggcaaac agcaagagaa gtacgaagtg ttggggaatt ggaagaagga
    83641 atacagcgtt tttggttatc aaaagaagca gtaaatcaaa aaaacgagga atgacagacg
    83701 tcagcctcgt tttttgatta acgatagtta gtgaattgca actcgattgg taagtcaagt
    83761 ttacgtaata aagcaatcac agcttgtaga tcatcacggt tcttacctgt cactctaatc
    83821 tgatcttctt ggatttgtgc ttttactttc agtttttcat ttttgatagc tgtagtgatt
    83881 ttcttcgcgt tttcacgatc gattccgttg accaaatcgg cagtttgtcg agctttgcca
    83941 cctagagcgt gttctgattc ggaaaaatgg atatttttga ttggcacatt tcttttgatc
    84001 agcttaccaa ataatacatc tttgatctgt tcgattttga aatcatcatc gctcaataca
    84061 actagattgc tgttctctaa tttgatttct actgtagaat ccttgaagtc aaagcgattg
    84121 gacaattctt ttgttgtttg ctgaatcgca ttttttactt cttctgtatt gacttctgat
    84181 acaatgtcga agctagcatc ttttgccata ggaaccctcc tgatatacat ataaatattt
    84241 accatacatc tatcttatca taggattagg gcagattctt acctgtttgc taaaattctt
    84301 ctcatttgag ttcgaagtat tttattttaa tagataaact gttattctta catttggaat
    84361 accaaagtag gggagaggtg cttgtgagta aaattatgac tgcgtatcat aaaaatgaaa
    84421 gattaaagaa aatagtggtt attttgataa ccggattgac cgctgcggtc gctttaaatt
    84481 attttttgat tccagccaat gtcttttctg cagggatgaa tgggatcgct caaatcattt
    84541 cctcgctttt atatgaatgg tttcatatca agatagacac aggaacattt atttttcttt
    84601 tgaatatccc tgtgtttgta ttagggtttc tcaaagtagg aaaacgagca acgatcctta
    84661 gttttgtgaa tgttgtatgt gtatcggtga tgacgatgct gcttccagtc ggacagatca
    84721 ctgataatat tttgatgaat gccctagtag gcggtgtttt attaggtctt ggcgtaggat
    84781 tatctttaaa aatgggcttt acaactggtg ggatggatat catctctctt gtactttcac
    84841 aaacaactgg aaaaacagtc ggaaactaca tgctgattct aaatggtatc attgtagtca
    84901 tcgcaggctt cttctttaac tgggaaagtg ccttgtatac gattatttcc atttatgcaa
    84961 tgactcaagt aattgatgcc atccacacga gtcatcaaaa agtaacagca atgatcgtta
    85021 ccgtcaagcc agaagaggta acagaagaac tagcaaaacg gatggtacgt ggaatgacat
    85081 tactgccgtc tgtcggtggc tattcaaaaa aacaagggaa catgatcatg atggtcatca
    85141 cccgctacga aatgtatgat cttgatcaga tcgttcatga aatcgacgac gatgcattta
    85201 tcaatatttt accaactcat tcagtatttg gccggtttgc aaatgaaaac gaacaaaaaa
    85261 tgtatcgaac aactggcgta ttgccagaaa taaaaaatcg ttcacaaaaa aaatgaggaa
    85321 tcaggtttat tttagaataa atttaatcta ttacatctaa taagaacatt tttataaatt
    85381 taaacgagaa tcttacttct aaattctcat ttacaagcag ctaaaaaaag agtatgataa
    85441 ataaaaatcg tgttaaggag tgtcgtacga tgagcgaagc aaaccaagaa cggtctggac
    85501 aagaaataga actaatcaaa gaacgtattc ttgctgcctt ggaaatggtg attgatcctg
    85561 aattaggaat cgacatcgtc aatttaggct tgatttatga tatagaattc aatcctgaaa
    85621 atggagaaac agtcattaag atgactctaa caactatggg ctgtccatta gcagatattt
    85681 taacagaatc tatccatgac gcattaaaag aagtgccaga agtaacgaaa gcagaagtca
    85741 aactagtctg gtatccagca tggacgacag ataagatgag ccgttatgca cggattgcgt
    85801 tggggatacg atagaaatct tggctgacta gctatgagaa gcaaatagga aaaacaaaaa
    85861 agccttttat cctttctaga agaaaagaga taaaaggttt ctttgtttat aaaattttgt
    85921 ctgctatatt ataagttaat taaataaatg tgttctattg ataaaggaca ttcaaatccc
    85981 tttccttttg gaatccttct tttttacatc agtttgattt tcgtatagta ttctttctca
    86041 tcttcacgat aaatcgcagc cccatttttt tgttgtgctt taagactgcc aagatttttt
    86101 ttatttacag acaaaagtgc ctcatcaatg ccgatttttt ttgcctcttg tagtactaat
    86161 gctaatcctt gtgtggcata tcctttttta cgataattag gggagatgcc gtaaccaata
    86221 tggccagcgc cgtttcttaa tgtttcgttc agtttatggc gcaaattaaa aattcctaca
    86281 tactcatgtt catcactttc taaaataaag acggttgcgg gaacgtaact ctcaggaaga
    86341 tcgattccta aagacgtttt ttcgcatttt tttacataat ctaaaaattc agcaaatgta
    86401 tagccataag cattgttgat aaatccactc tcatttggtc caaagctagt ttgtagctga
    86461 taagctttct ttaaatctgc ttcccatagt ttgatcagtt tcatcgtatt cacctcttta
    86521 agtaacctta ttcatttgtt ttctactata gcactattgt tgtaaatagc catgcctatt
    86581 tttatttatt gtgtcatatc gtattaagaa tcatcgaaca atacaaatat gaattacaat
    86641 aaaaaaatta tttgaagttc gttcattcgt tacttatgat ctctagaaga aagaaaacgt
    86701 gaattacttc agcgtctaga attccagaag gatagtaatc aacagaagaa ataatcaata
    86761 tccaaatgaa agaagatagc tgaatcgaga aaaagaggaa aaaagaaatg aagaaaaaaa
    86821 taaaatagtt actaatccca gagtcgttcg tttaacattg aaatcgatca tatggataaa
    86881 acagattttt tcaccaaccc tcaatagatg atggagttgc tcggatgaat tatttgtgta
    86941 gatggcataa gggagggcgt acagaaatga aaaagaacaa aaatatgttc ttgacaaaaa
    87001 acacatgtaa tcctaaacta aaagatgtga tgcggctatg gcggaattgg cagacgcgct
    87061 agcttcaggc gctagtgagg gtgacctcgt ggaagttcga gtcttcttag ccgcataatt
    87121 tgttttttta taaagagaag gtacacctgg agcgatgaga aagaaaataa catattatct
    87181 aaaagaatat aggaaaaatt ttaaacaacg gaaccagatt caaataaatc aaaaaaaatt
    87241 tgtgtgaagg tgggacagtt taaaacctaa tagattgatt caaatagtag atttatagat
    87301 tctgatacaa gaaatactgg caaacgatag ttaaggaata aagactaaac ttaaactcaa
    87361 aaagaggtca tgcgaaagaa taaatcgcat gacctcttac tatattttga atgtgtttaa
    87421 acgttcaaat aatgaatctt agtaccaacc gtttgcttcc cagaatgctt tcgccgcttc
    87481 ccaagaacca taacgtgaag taacatattg ttctgctact ctttcttggt ttgcagcaga
    87541 gtagtcacca tttaagtaag aagaatctaa ttggtaacgg ccgatgtaac gtccgttcgt
    87601 tgctgtgtaa gaaccgcttg attctttttg tgcgatccat tcttttgcag agcttgtact
    87661 tgctggagta gcagcagttt ctgttacagc aggagcaggt tgtgtttcag caacaggcgc
    87721 tgcttgtgtt tccgtttgaa ccgtttcttg tacaacaggt tgttcagctt gaacaggttc
    87781 agcttggact ggtgcttctt gaacggctgc ttgaggttca gcagctgctt gtgcagagcc
    87841 ttctgttggg attgttaatt gttgtcctga gta
//
LOCUS       DAIGSZ010000004        80337 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.004, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000004 DAIGSZ010000000
VERSION     DAIGSZ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 80337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.004"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            172..444
                     /locus_tag="NOB31_000270"
     CDS             172..444
                     /locus_tag="NOB31_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972517.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            459..1382
                     /locus_tag="NOB31_000271"
     CDS             459..1382
                     /locus_tag="NOB31_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0972518.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(1522..2274)
                     /locus_tag="NOB31_000272"
     CDS             complement(1522..2274)
                     /locus_tag="NOB31_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0972519.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            2497..2859
                     /locus_tag="NOB31_000273"
     CDS             2497..2859
                     /locus_tag="NOB31_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCI0972520.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            3496..4968
                     /locus_tag="NOB31_000274"
     CDS             3496..4968
                     /locus_tag="NOB31_000274"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HCI0972521.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            4980..5804
                     /gene="nadE"
                     /locus_tag="NOB31_000275"
     CDS             4980..5804
                     /gene="nadE"
                     /locus_tag="NOB31_000275"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HCI0972522.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(5877..6767)
                     /locus_tag="NOB31_000276"
     CDS             complement(5877..6767)
                     /locus_tag="NOB31_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HCI0972523.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            6965..8482
                     /locus_tag="NOB31_000277"
     CDS             6965..8482
                     /locus_tag="NOB31_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCI0972524.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            8454..9743
                     /locus_tag="NOB31_000278"
     CDS             8454..9743
                     /locus_tag="NOB31_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0972525.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            9918..10814
                     /locus_tag="NOB31_000279"
     CDS             9918..10814
                     /locus_tag="NOB31_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0972526.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            10828..11691
                     /locus_tag="NOB31_000280"
     CDS             10828..11691
                     /locus_tag="NOB31_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0972527.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            11697..12261
                     /locus_tag="NOB31_000281"
                     /pseudo
     CDS             11697..12261
                     /locus_tag="NOB31_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            12283..13794
                     /locus_tag="NOB31_000282"
     CDS             12283..13794
                     /locus_tag="NOB31_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCI0972528.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            13806..14765
                     /locus_tag="NOB31_000283"
     CDS             13806..14765
                     /locus_tag="NOB31_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCI0972529.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            14851..15930
                     /locus_tag="NOB31_000284"
     CDS             14851..15930
                     /locus_tag="NOB31_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0972530.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(16182..17582)
                     /locus_tag="NOB31_000285"
     CDS             complement(16182..17582)
                     /locus_tag="NOB31_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HCI0972531.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            17800..19461
                     /locus_tag="NOB31_000286"
     CDS             17800..19461
                     /locus_tag="NOB31_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HCI0972532.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            19418..20116
                     /locus_tag="NOB31_000287"
     CDS             19418..20116
                     /locus_tag="NOB31_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCI0972533.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            20132..21556
                     /gene="araA"
                     /locus_tag="NOB31_000288"
     CDS             20132..21556
                     /gene="araA"
                     /locus_tag="NOB31_000288"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HCI0972534.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            21863..23023
                     /locus_tag="NOB31_000289"
     CDS             21863..23023
                     /locus_tag="NOB31_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HCI0972535.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            23141..25000
                     /locus_tag="NOB31_000290"
     CDS             23141..25000
                     /locus_tag="NOB31_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI0972536.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            25110..25544
                     /locus_tag="NOB31_000291"
     CDS             25110..25544
                     /locus_tag="NOB31_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972537.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(25803..25964)
                     /locus_tag="NOB31_000292"
     CDS             complement(25803..25964)
                     /locus_tag="NOB31_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972538.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(25983..27005)
                     /locus_tag="NOB31_000293"
     CDS             complement(25983..27005)
                     /locus_tag="NOB31_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HCI0972539.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            27133..27486
                     /locus_tag="NOB31_000294"
     CDS             27133..27486
                     /locus_tag="NOB31_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCI0972540.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            27498..28664
                     /locus_tag="NOB31_000295"
     CDS             27498..28664
                     /locus_tag="NOB31_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0972541.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(28756..29376)
                     /locus_tag="NOB31_000296"
     CDS             complement(28756..29376)
                     /locus_tag="NOB31_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HCI0972542.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(29568..29864)
                     /locus_tag="NOB31_000297"
     CDS             complement(29568..29864)
                     /locus_tag="NOB31_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI0972543.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            30068..30718
                     /locus_tag="NOB31_000298"
     CDS             30068..30718
                     /locus_tag="NOB31_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCI0972544.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            30734..32461
                     /locus_tag="NOB31_000299"
     CDS             30734..32461
                     /locus_tag="NOB31_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0972545.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            32458..34350
                     /locus_tag="NOB31_000300"
     CDS             32458..34350
                     /locus_tag="NOB31_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0972546.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            35054..35923
                     /locus_tag="NOB31_000301"
     CDS             35054..35923
                     /locus_tag="NOB31_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HCI0972547.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            36132..37157
                     /locus_tag="NOB31_000302"
     CDS             36132..37157
                     /locus_tag="NOB31_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCI0972548.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            37196..38146
                     /gene="manA"
                     /locus_tag="NOB31_000303"
     CDS             37196..38146
                     /gene="manA"
                     /locus_tag="NOB31_000303"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HCI0972549.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            38240..39943
                     /locus_tag="NOB31_000304"
     CDS             38240..39943
                     /locus_tag="NOB31_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0972550.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            39945..41978
                     /locus_tag="NOB31_000305"
     CDS             39945..41978
                     /locus_tag="NOB31_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI0972551.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            41989..42429
                     /locus_tag="NOB31_000306"
     CDS             41989..42429
                     /locus_tag="NOB31_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0972552.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(42629..43756)
                     /locus_tag="NOB31_000307"
     CDS             complement(42629..43756)
                     /locus_tag="NOB31_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0972553.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(43759..44436)
                     /locus_tag="NOB31_000308"
     CDS             complement(43759..44436)
                     /locus_tag="NOB31_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0972554.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            44700..46466
                     /locus_tag="NOB31_000309"
     CDS             44700..46466
                     /locus_tag="NOB31_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HCI0972555.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            46481..46918
                     /locus_tag="NOB31_000310"
     CDS             46481..46918
                     /locus_tag="NOB31_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0972556.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            46931..48082
                     /locus_tag="NOB31_000311"
     CDS             46931..48082
                     /locus_tag="NOB31_000311"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCI0972557.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(48144..48842)
                     /locus_tag="NOB31_000312"
     CDS             complement(48144..48842)
                     /locus_tag="NOB31_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HCI0972558.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(48835..50187)
                     /locus_tag="NOB31_000313"
     CDS             complement(48835..50187)
                     /locus_tag="NOB31_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HCI0972559.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(50410..51810)
                     /locus_tag="NOB31_000314"
     CDS             complement(50410..51810)
                     /locus_tag="NOB31_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HCI0972560.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            51971..52708
                     /locus_tag="NOB31_000315"
     CDS             51971..52708
                     /locus_tag="NOB31_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HCI0972561.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            52833..53312
                     /locus_tag="NOB31_000316"
     CDS             52833..53312
                     /locus_tag="NOB31_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HCI0972562.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            53309..54076
                     /locus_tag="NOB31_000317"
     CDS             53309..54076
                     /locus_tag="NOB31_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972563.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            54306..54875
                     /gene="lepB"
                     /locus_tag="NOB31_000318"
     CDS             54306..54875
                     /gene="lepB"
                     /locus_tag="NOB31_000318"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI0972564.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(54979..55581)
                     /locus_tag="NOB31_000319"
     CDS             complement(54979..55581)
                     /locus_tag="NOB31_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI0972565.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            55687..56156
                     /locus_tag="NOB31_000320"
                     /pseudo
     CDS             55687..56156
                     /locus_tag="NOB31_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            56262..56846
                     /locus_tag="NOB31_000321"
     CDS             56262..56846
                     /locus_tag="NOB31_000321"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HCI0972566.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            56849..57922
                     /gene="prfA"
                     /locus_tag="NOB31_000322"
     CDS             56849..57922
                     /gene="prfA"
                     /locus_tag="NOB31_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HCI0972567.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            57915..58754
                     /gene="prmC"
                     /locus_tag="NOB31_000323"
     CDS             57915..58754
                     /gene="prmC"
                     /locus_tag="NOB31_000323"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HCI0972568.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            58747..58926
                     /locus_tag="NOB31_000324"
     CDS             58747..58926
                     /locus_tag="NOB31_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972569.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            58948..59973
                     /locus_tag="NOB31_000325"
     CDS             58948..59973
                     /locus_tag="NOB31_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HCI0972570.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            60164..61408
                     /locus_tag="NOB31_000326"
     CDS             60164..61408
                     /locus_tag="NOB31_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCI0972571.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            61561..62508
                     /locus_tag="NOB31_000327"
     CDS             61561..62508
                     /locus_tag="NOB31_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0972572.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            62642..63271
                     /gene="upp"
                     /locus_tag="NOB31_000328"
     CDS             62642..63271
                     /gene="upp"
                     /locus_tag="NOB31_000328"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HCI0972573.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(63410..63652)
                     /locus_tag="NOB31_000329"
     CDS             complement(63410..63652)
                     /locus_tag="NOB31_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972574.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            63773..63845
                     /locus_tag="NOB31_000330"
     tRNA            63773..63845
                     /locus_tag="NOB31_000330"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:63806..63808,aa:Thr,seq:cgt)
     gene            complement(63964..64602)
                     /locus_tag="NOB31_000331"
     CDS             complement(63964..64602)
                     /locus_tag="NOB31_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI0972575.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(64725..65357)
                     /locus_tag="NOB31_000332"
     CDS             complement(64725..65357)
                     /locus_tag="NOB31_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCI0972576.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            65708..66007
                     /locus_tag="NOB31_000333"
     CDS             65708..66007
                     /locus_tag="NOB31_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCI0972577.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            66502..68667
                     /gene="acm"
                     /locus_tag="NOB31_000334"
     CDS             66502..68667
                     /gene="acm"
                     /locus_tag="NOB31_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HCI0972578.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(68939..69424)
                     /locus_tag="NOB31_000335"
     CDS             complement(68939..69424)
                     /locus_tag="NOB31_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HCI0972579.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    69514..69859
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            69904..70545
                     /locus_tag="NOB31_000336"
     CDS             69904..70545
                     /locus_tag="NOB31_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI0972580.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            70564..71199
                     /locus_tag="NOB31_000337"
     CDS             70564..71199
                     /locus_tag="NOB31_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI0972581.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            71217..72032
                     /locus_tag="NOB31_000338"
     CDS             71217..72032
                     /locus_tag="NOB31_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0972582.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            72351..73787
                     /locus_tag="NOB31_000339"
     CDS             72351..73787
                     /locus_tag="NOB31_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0972583.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            73976..76423
                     /locus_tag="NOB31_000340"
     CDS             73976..76423
                     /locus_tag="NOB31_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCI0972584.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            76653..77720
                     /gene="rlmN"
                     /locus_tag="NOB31_000341"
     CDS             76653..77720
                     /gene="rlmN"
                     /locus_tag="NOB31_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HCI0972585.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(77913..79016)
                     /locus_tag="NOB31_000342"
     CDS             complement(77913..79016)
                     /locus_tag="NOB31_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0972586.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            79568..80116
                     /gene="aac(6')"
                     /locus_tag="NOB31_000343"
     CDS             79568..80116
                     /gene="aac(6')"
                     /locus_tag="NOB31_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCI0972587.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT        26863 a        13805 c        16530 g        23139 t
ORIGIN      
        1 attcactaat aataaagata tatttacagt atcattataa tgtattcaat ttaaaataag
       61 agactttggt aataatgaaa gaggaataaa acttttcttt ggcaaaacaa actccttgct
      121 atgagacgcg tttcatacac tatactcaaa gtatcaaaag gagggcttgc aatgaatact
      181 tatgtagaga taacagatgg cacaacgaac aattattttt atgcgtttgt cgagttcaag
      241 ggatccgtat taacgttgta cagttttcaa gggttgaata ggaatatagt aaaagaaata
      301 ccaatgaatg aaatcgaaaa tttgacaaaa gatatatatt ggggcgggca gcggatcagt
      361 ttttcgcatg aaggaaaaat gtatcagttt tttgaatgcg gtccagctgt ggtagactat
      421 ttacaagaaa atctttttgt ataggtggcg aagcagcagt ggcaaacatt cgagatatcg
      481 caaagctcac aggttattca gtttctacta tttcacgtgt aatcaatgga catccatatg
      541 tagatgagga aaaaaggaaa gaaatacttg cggtcatgaa agaagtcgat tatatcccta
      601 atgcaaatgc cagacagtta agttatggaa aaacgaaaag cattggagtg attctgcctt
      661 ataccaatca tccgtatttt gatcagttga tcagtgggat cattgaagca gcgtttgatt
      721 atgattacaa agtgacactt ttaccgacgg gctatcataa agaaaaagag cgaaggtatc
      781 ttgaagaatt tgcagctaaa gctttcgatg gattgatcat tacgtctcgt gccaatacac
      841 tagatgattt attggcatat caaaaatatg gacctctagt tttttgtgaa gaaatcaagg
      901 gaaaacaggc aagctgtgtc tttattgatc gagaacaatc aattacagaa ggtcttactt
      961 atttgaagca gcaaggtata aagcaattgg gcatcacgtt ggggcgaagt ggcaggctaa
     1021 gttataactc aaaaatcact ttgcagctat gtcatcaact ttttccatct tttgatgaat
     1081 cacttgtttt ttgggattgt atagatgcag agaaaggaaa acaagcaggc ttctttttta
     1141 aagagcttgg agttgatggt gtctttacaa attcggatat ggttgcagca ggcatcttgc
     1201 aaagctatct gcaagataag acaccagtgg tgattggacg cgataatttg ctgatcagcg
     1261 agcttcttgg tttcccaacc atcgaccacc atctggaagc ttgcggagaa atggcatttc
     1321 aattgtttct tacagaaaaa aaggataaag tgaaaatacc ttatacgttt attcaacgat
     1381 gaatatattt aaagtaggat gaaaaaactt gtgaaagaat ggagcagaca ccaaaagtta
     1441 gcataaaaat ctaacttggg tgtctgctgt tttgttatta ggtcatttta cgtgtacttt
     1501 tttgttggat catgtaaaag attacgcctt tttttggata atttcattta aagcttttgc
     1561 tgcaccatga ccacttcgct cgtcataata tgcagtgaac cgttcatcgg cttcgtacat
     1621 cattcctagt cctttatgcg cttttggctg atattcaggc cagctgtaag agaaccactt
     1681 cttatgagct tggaagatac ggtctgctaa gctttcatct tctggttctt ttaagtaaag
     1741 agtgagatca aataacatct gcttttcaac agtttgcatt tcttcatacg tttctttatc
     1801 catattcatc catttttcat tggatgctgt aacctttttt tttccgtatt tttgtcgaat
     1861 ctcttgtcca taggattctt cattttcttt caacttttgt tgtttaaacc cttcaaattt
     1921 ttctttgtca ctcatttttc ttcctccttc gtacatatca agtgtctgtt ggacagttgt
     1981 caagagggta tcgatttgtg cccgtttttc cagcaacatt tgctgatgct tgattaaagc
     2041 tttctggtgg tcaaaagatg gattgtctaa gacctcttgg atatcatcca acttgaatgc
     2101 cattgttcga taaaataaga tgtgttgcag acgatcgact tcttttttgc cataaatccg
     2161 ataacctgaa gaattgatcc tagctggttt tagcagtcca atctcatcat aaaagcgcaa
     2221 ggttctcgga ctgactcctg atatctctga cattttcttt attgtgtact ccattatttt
     2281 tcctcctgac aaatgtaagc ataatccttt acgtaacgag atggtcaaga aaaaattgta
     2341 tttttttctc acgaaattat gttatactat taagtgataa aaggtaaatc cttttgtctt
     2401 taaaggttca attgtaaccg attccttaat gctaggaaag atggtaacat aacttaagat
     2461 tggatctaaa tcgactatat agaaaagagg aatgagatga agctaatcga aacacctgtg
     2521 aatagtaatt taaatattaa gacattttat cctaaagtag tggaattctt ttttgggaat
     2581 acggctatta attattacaa attattttcg ttagatcgaa cacaactgct attggtagac
     2641 acatatgata aaaagcaagt cgtgatgatc aatacgaaga aaaaaatcac aaggcaagaa
     2701 atcgactatg cgattcatca cgttttaaaa atgacacgag aagatgtcaa agtccatgta
     2761 ggagtgaaac aggagctaga acgtgccgga atacaattca aacgtccaaa taaagatatt
     2821 gtagtgatag aacaaaaaaa tacgaaggat tctatttaat aacgactaat aatcatcttt
     2881 atggtaacct gctccatatc taatgtatac aataaaaaac aaggcgagac tgattgatgt
     2941 ctcgccattt ttgtttccat tctattgaca gctgctttct tactttgtat ctttttaaaa
     3001 acgtgtgata ttttttccgc gagttttttc aacgcaaggt atatcttgtc ataattcgcc
     3061 tttccaaaaa aattcaatac ataataagtt atatccgttt ctttggggat aagaagcaaa
     3121 aaaggaaaga cgtattattg cttcaaaaac ttttgccatt gattatgttg tagagacatt
     3181 tggttatatt tgttcaatca tcggtatctt aacggctacg attgtagtag gaaaatctac
     3241 ttattttatc aagtaagaaa aatagaaaac gctaatttct tcgtgtctcg gatacattga
     3301 ataaaataag tattctttct cgtttaggtt aaataccaat aagaaaggat agttttagca
     3361 gatggagttc atttttagca agaaatatcc gtaaaacatg tgctttttca gaaaaaatgg
     3421 aagatttctt ttcctattaa ttttttttgt tataatgggt aggaaatgaa aacttgccaa
     3481 gaggagtaat acaagatgaa taatacttac ccagacgaca gtttgacgct gcatacggat
     3541 ctatatcaaa tcaatatgat gcagacatac tgggaattag gtcgagctga tttacatgct
     3601 gtttttgaat gttactttcg agaaatgcct tttaaccacg gatacgcggt ttttgcagga
     3661 ttggaacggt tagtcaatta tttagagaat ctgacgttca atgattccga tattgcttac
     3721 ttgcgtggat tagaagtcta tcctgaaggt tttttggagt atttacaaaa ttttgaattt
     3781 aaagcaacag ttcgttctgc tcgtgaagga gaactagttt ttgcaaatga accattaatc
     3841 caagtggaag ggcctttagc gcactgccaa ttagtagaaa cagcactgtt gaatatggtc
     3901 aatttccaaa cgttgatcgc gacaaaagca gctcgtatca aatctgtcat cggagaagat
     3961 ccactattgg aatttggaac tagacgggca caagaactgg atgcagcagt ctggggaact
     4021 agagcggcat atatcggcgg agcagatgca acaagcaatg tacgtgctgg gaagatattt
     4081 gggataccag ctagcgggac ccatgctcat tcgttagtcc aatcttatgg aaatgattat
     4141 gaagcattta tggcctacgc taaaacccat aaagactgcg tgttcttagt cgacacttat
     4201 gatacgttga aatcaggtgt gccaagtgcg attcgcgtgg cgaaagaatt aggtgacaaa
     4261 atcaacttcc aaggcgtacg catcgacagt ggagatatgg cctatatatc taagcgtgtt
     4321 cgggaacaat tagatgcagc cggatttacg gaagcaaaaa tctatgcttc gaatgacttg
     4381 gatgaagcaa cgattttgaa tttaaagatg caaaaagcta aaattgatgt atggggtgtt
     4441 gggacaaaat tgatcacagc ctatgatcag ccagcccttg gtgcagtatt caagctagta
     4501 tcgatcgaag atgatgaagg aaaaatgatg gatacgatca agttatcaag caatgcagaa
     4561 aaagtaacta ctccagggaa aaaacaagtg tggcgcatca ctcgaaattt tgatgggaaa
     4621 tctgaaggag actacgtgac attatgggat gaagaccctc gagaagaaga agctatcttc
     4681 atgttccatc cagtgcatac gtttatcaat aaaactgttc gagactttac agctcgccca
     4741 gttttacaag atatctttat cgaaggaaaa agagtttacg aattacctgc actaaacgaa
     4801 atcaaagaat atacaaaaga aaatctagat tcactatggg aagagtataa acgagacttg
     4861 aatccgcaaa aatacccagt cgatctgtct actgaatgct ggaaccataa aatggctatc
     4921 atggaacgaa tgaaaaaaag cgtagcagaa cttcatacag aagcatagga ggagaataaa
     4981 tgagcctgca gacagaaatt atcaatgaat taggtgtcaa accaacaatt gatccaaaag
     5041 aagaaatacg taaaagtatt gactttatga aagcatattt gaaaaaatat ccgtttctta
     5101 aaacttttgt actaggtatc agcggcggcc aagattctac tttagcaggc cgtttggcgc
     5161 aactaacgat ggaagaaatg cgtgaagaaa caaaagatga aaactatcaa tttatcgctg
     5221 ttcgtcttcc ttatggtgaa caagcagatg aagaagatgc aaaagctgct cttgacttta
     5281 tccagcccga tgttagtctg cgagtaaata tcaaaccagc tgttgatgca caagtacaag
     5341 tattaagcga agcaggtgtg ggaatcagcg attttaacaa aggaaatatc aaagcacgtc
     5401 aacgtatgat tacgcaatat gccgtagctg gagaaagagc aggagccgta ttagggacag
     5461 atcatgctgc agaaaacatt actggattct tcacgaaatt tggtgatggt ggagccgaca
     5521 ttttgccatt attccgtttg gacaaacgac aagggaaaca attgcttcaa gcattgaatg
     5581 caccggaaaa attatacaca aaaattccga ctgcagatct tgaagatggg aaaccaatga
     5641 ttgcagatga agtcgcacta ggtgtcacat ataatgaaat tgatgattat ctagaaggaa
     5701 aagaagttcc cgctcaagca caagaaaaaa tcgaagcatg gtggaacaag acacaacata
     5761 aacgacattt gccaatttcc gttttggatg atttctggaa ataacaataa agcaaaaaca
     5821 gccgtccctt catagggatt ggctgttttt gttttataaa atagaaaaga aaaatatcag
     5881 ctgtagtaaa cttttaattt gatatcctga tcgtaattac cgaatccttt accaaataaa
     5941 gtacagcccc ccacatgttt ggcatcgtct ttcacttcga ttcgcaaatg ccaagtgtct
     6001 tgctctttag ggatgtcgtt gatcgtgatg tttgacaagg gttctccatt catattcgtc
     6061 aagtgtttgg taattcggat cgtcttcagc aagccgtatt gattaagatt atctggatac
     6121 caatcaggcg tatatttacc gcggatatca gcaaaatctc cagggctcgt ccatgttcct
     6181 agctccacac catttaggct gaaagtgata tctgaaggcc aattgtcatt tgaaaaagga
     6241 aattcagaag aaatttccac agaaacttcc aacatctcca atgtatcctc tgtatttaaa
     6301 aaattaggtg cctgatactc gacaaatccg ctggtaaacc agagaatgcg ggcatccatc
     6361 cttcgaggat ccataaaata gcgtggttca tccactttcc cgataaaatc atggatcgta
     6421 gctaaaccgc atgttggttc aattgcataa tttgtatagt gaccaatagg tatcgatgtt
     6481 tctttcgtat caaaagcatt gaatattttt tctggaaaac tgatatcgat tttatcgaca
     6541 cgaaggctcg aaattttttg ttgtcctact ttttctgttt tgatgatgtt tgcttcctct
     6601 agctttttca cgtgcatcgt cgtgatagca ctgctcactc caagttcttt tgccaaatct
     6661 ttgacattca tctttttttt ggaaagtagc tggatgatct tgatccttgt tttactagct
     6721 aatgcttcat ataccggtaa ggattcttcg tttatttgta gttgcatata tatcacctct
     6781 taaaaggttt ttcttatata ttaacatatt tgttaataaa agttatatta aattatttgt
     6841 tttaatcatt attaatattt tggttaatta aaatcgataa aaaataagta agtttaacat
     6901 ttatattatt gacaacgctt tcaacgaggt gtattattca tgtataaatt aaaggaggtc
     6961 agttatggaa gccacaatgt tgattagtag tgtcaagcgt gtaggcaaag ttgatccgcg
     7021 gttgtacagt tcatttattg aacatatggg acgagcagta tatgaaggga tttatcagcc
     7081 agatcatcca tcagctaata aaagtggatt tcgccaagac gtcattcact tggtaaaaga
     7141 attgaacatt cccatgatta gatatcctgg tggaaatttt gtgtcaggat ttcgttggga
     7201 agacagtatt gggcccatag caaatagacc tagaaggttg gatttagctt ggcggacaat
     7261 tgaaacgaat gaagttggga ttcatgaatt ttataactgg tgtcagcatg tgggggccga
     7321 aatcaatatg gctgtcaatc tgggtactcg tggagtagat gcagctcgta atttagtcga
     7381 atattgtaat tttcctaaag gaacttattg gagtgattta aggcgttcga atggtcaaga
     7441 gagccctttt ggaattaaga catggtgttt agggaatgaa atggacggtc cttggcagat
     7501 tggacataaa acagcggaag aatatggacg gttagcagag gaaacggcta aggcgatgaa
     7561 actcgtagat gattcaattg aggtggtttt atgcggaagt tcgaatcggc aaatgcctac
     7621 atttggtgat tgggagttaa cagttcttga tcaagcgtac gatcaaatag attatttgtc
     7681 tctgcatcaa tattatggca accaaaaaaa tgatctttct cattatcttg cacgttcctt
     7741 agacatggat cggttcattt ctgaagtgac agcgatgtgc gatacagtca aggcgaagaa
     7801 acatagtaag aagcagatca acctgtcctt tgatgaatgg aatatttggt atcattcagc
     7861 ggaacaagat gagcaagcag cgccttggca gattgctcct cctttactag aagataacta
     7921 taattttgaa gatgcattac tattaggctg tctattaatc actttattga aacatgcaga
     7981 tagagtaaag attgcttgtc ttgctcaatt ggtaaatgtt attgcaccaa tcaggacaga
     8041 aacaaacgga gaagcttgga gacagacgat ctattatcca tttatgcaag ctgctgtgta
     8101 tggacaagga gaggtgttaa gcccacaaat tcgttcagca aactatgcga cggaagattt
     8161 tgaagaagtg ccgtatttag aaagtatagc cgtaataaat gacaaagaac ttgtcatatt
     8221 tgcagttaac cgtggagaag aagaaatgaa tctaactgtt cacttgtctg aattatcatt
     8281 agagggagtg attgattttt ctgaaatgag tggatttgat acaaaagcaa ctaatcttcc
     8341 taaaagtgaa caagtaaaac caagtcattc aacaaatgta aaagctgaag atgggaaaat
     8401 caattgttta ttgaaaccgc tatcttggaa tgtggtcaga tgtcgtttat cagatgaagg
     8461 aggaacaaaa aatgaaaggt aaaaaatggt taattggctc tttgttggta gctgcaacag
     8521 gtattttagg agcttgcggt ggcggaagtt cagcagaatc tgattctgat aaagaagtga
     8581 ctttgacttt ttggaatggg tttactgcat ctgatggtga aatattgcaa gaaatcgtta
     8641 atgaatttaa taaaacaaat gataaaaaca tcaaaattga aatggatatc atgacttggg
     8701 ccaatttgaa tgaaaaactt cctacagcga tttcttctaa aaaagcacct gactttattg
     8761 cattaaatta tccagatttt gcacagtatg tagaaaacgg agcggtacaa ccattagacg
     8821 atttctggga atatgatgga gtagataaat ctgattttaa agaaacggct attgaattag
     8881 gtgaagtaga aggtaaacag tattttgtcc ccatgcaggt acaaggcatg tatatgtatt
     8941 ggaataatga tttgtttaaa caagctggat tagatactga acaaccacct actacttggg
     9001 aagaattgac agaaatggca ccaaaattaa ctgatagtag taaaaatgta tcaggttttg
     9061 tcttcaataa ggatggaact gcaccgttat ataactggat gttagcaaat ggcggtaaat
     9121 tagtgaacga tgattatact aagtctgaat ttgcgtctcc tgagaacctt aaaacgttaa
     9181 aagcgatcca aaaaatgatc catgtagaca agactggtcc agaatcgatt tctggcgccg
     9241 aaatggacaa tttaatgaat gctggtcaac tagccattga aatcaatggg ccatggttaa
     9301 ataacggatt gaaagcaaac gagattgatt ataatgtgac taccttacca caagggagtg
     9361 attcagacaa aaaaacagct attttagatg gcgtaggata tgccattccg gcaagtacag
     9421 ataataataa aaaagaagct gtctatgagt ttttgaaata ttggaataca actgaaattg
     9481 gtaaaaaatg gagtatcgaa aatggttttc ctgcctactt ggattcagta gcaaaagatg
     9541 aagaagtaaa aaatgatcct attgtatctg aattatcgaa acaaatggac tatgcagagc
     9601 catatttacc aggttttacc caaatctctg cgatcaataa cgatatcatc aatccactga
     9661 ttgaaaaatt attagcagga gaagatcctg agacactcat gaacgatgca gatgatgcca
     9721 tcaatcaatt actgcaaaaa tagtacagaa ctttatacag gatagactgt tggcaagata
     9781 cagatatctg aatgatcgac ctagtatttg cagataggtg ttattgcaaa aatcacagcg
     9841 attgttcgga tatcttattc agattcgttt aaaccaagat tgtatatttt atcaaaatga
     9901 aagatgaggt ggactatatg aacggattca ccaaatattg gaatcgtcct gatcgtgctg
     9961 cgtatttgtt tttaactcca tcttttttag ttttattatt atttactgtc ataccgcttt
    10021 taggaacatt tgctattagt tttacagatt tgaatatttt ctttacatca agaaattttg
    10081 taagttttga aaatttcaca cgtatattta gtgatgaacg agcagttaat tcgttgattc
    10141 attctttata tttcaccgta ctcgaaacgc caacacaaat tatcgttggt ttattagcag
    10201 cagtagcatt atctaaaaat accagattca atcgtttttg tcgttcgaca ttttacattc
    10261 cagttatttg ttcattgacg tcaattgcga ttattttttc tatgttgctt gatccgaatg
    10321 taggggcgat tccttacttg ttttcacaag tcggcttgcc gatccctcaa ttttttcgcg
    10381 atccaaccct tgctatgccg acggtagcca tcatgactgt ttggaagaat tttggtgtta
    10441 ctatgacgat tctcttgact gctattcagg gaatctctcc ctctttgtat gaatctgctc
    10501 aaatggatgg tgcaacaaat cgacagcagt tttttaacat tacgctacct cagatcgttc
    10561 cctccttagg tttttgtatt ttaacgaatc tgattggttc gatgcaagtg tttgaccaag
    10621 tatatgttgc aaccgctggt ggcccacaat ttaagacaga aacagctgtt caatatattt
    10681 acagtcgagg atttacagca ccttatgaat tgggctatgc atcagcactg tcttcggttt
    10741 tgtttatcat tgttgcaact atagctatct ccactaatgt gtacatgtca cggaaagaaa
    10801 aacaaatgaa ataggaggga aacctgtatg gcaccagaaa gctcgattac agttactgtg
    10861 aatagtcgaa aagcagttag tggtaaaaaa atcattcgaa cgattagtat gctagttata
    10921 ttgttggtta ttgcgtttcc ttttttgtgg ctgattattt cttcttttaa acacgaaaaa
    10981 gacattatct catttccgcc tagaatattt gcagatagct ataccctaga taactatatt
    11041 aaggtttgga caacgatccc tttattagat tacatcaaaa atacagtgat ttttgctgga
    11101 gggacagtga tcacttctgt attctttgat tctcttgcgg ggtatgcatt tgctcgtatg
    11161 cgtttcaaag gaaaatcagt tttgttctat ttcgttttgc tgacaatgat gatcccattc
    11221 caagtcttca tgattcctct atttattgaa gtcaatttgc ttggcatgct tgatacttat
    11281 gcaggtttga tcattcctcg tatgacaact gcatttggta tcttcatgat gcgttccttt
    11341 tttattactt taccagattc tttggaagag gcagcacgca ttgatggatt aagtgagttt
    11401 aatatttttt tgaaaatcat gttgccattg agcaaaccta ctcttttatc attagggatt
    11461 ttcacgctga tgaatagttg gaatgacttg ctttatccat tgatattgac aagtagttca
    11521 aaaatgagaa ctttaccagc agggttagct ttatttacag ggcagaacat ttctttttat
    11581 ggacctgtaa tggctggaac ggttatttca atgctgccat tactagtggt ttatattttt
    11641 gcacagaaat attttgttca aggaacagct atgtctggaa tgaaagagtg aggaagatga
    11701 aaatagttga gactaaactt tatggacagt tgattgtggt ttctgattac atcttattag
    11761 gtattctctg ggtaatcgtg tgtttgcctg ttattactat cgtgcctgct acatgtgctg
    11821 tttttttatg taatggcgca atggaaaggt gagggatcag gaaatatcat ttattttttc
    11881 tttcaaggaa taaagcaaca ttttggtaag aacttgttcc ttagtctgtt aacgatcatt
    11941 atttattttc ttgttaatca attattagaa gaacagacaa tcgtactttc aattagtgga
    12001 tatgtagttt tacttattta ttccatgttt cttttatcct ggatatatgt gatttctgaa
    12061 aacaaagata tcacattttt acaaattttt gaacaaagtg catggaaagt attttttgat
    12121 tttttgagaa atattctttg ttgcgtattg ttattaggat ttgtactgct catatttctt
    12181 ttccctcctt ttatttttat ctttgctggt ggcgtatgga aacttgtatc tattatcttg
    12241 actataggaa atgaaaggta gggaaagctg ttggacgaag aagtgaaagt aaaaatcaga
    12301 gaggatttta cggtaggaga gatcagttct cggctgtttg gctcatttgt tgagcatatg
    12361 ggaagtgtcg tctatacagg gatttatgaa ccgggccatg aaacagctga tggtgacggg
    12421 tttagacaag atgtcctctc ttatgtaaag gaattagaat taggtgtcat tcgctatcct
    12481 ggaggaaact ttacatctgg ttatgattgg gtggatactg taggtaggaa agaacaacga
    12541 ccaaaaaaaa ttgatttagc atggcgaggt atagaaccaa attcttttgg actccacgaa
    12601 ttttttaaat ggatcagtca tgtacaagcg aaaccgatat tcacggtgaa tttaggaaca
    12661 aaaggaattg atgaagcaaa aaatttagta gaatattgta attttccaaa aggaaccttc
    12721 tggagtgatt taagaataaa aaatgggcaa aaaaagcctt ttggcgttaa attatggtgt
    12781 ttagggaatg agctagacgg tccatggcaa gtgggggcta agagtgctta tgaatatggt
    12841 aggttagcaa atgaagcctc aaaagtcatg aagttagtgg atgattcaat tgaaacaatc
    12901 ttagttggaa gctctacgcc acgtttacca tcgtaccctg aatgggatcg tatcgcatta
    12961 gaagaagctt atgagaatgt agattattta gctttgcata actatattga taagtatgat
    13021 gaagaagact tgactaaacc tcctaaaaat gagcgtgatg atacagcgac ataccttgca
    13081 aaagcttatc gattcgatcg tcaaattgaa gaaatcgttg ctacttgtga ttatgtaaaa
    13141 ggatatttga gaagtgagaa aacaatgtat ctagcgtttg atgaatggaa tgtacatgcc
    13201 caaccggaaa aaagacatag ggattttgaa gtcggtagtc ccatcgattg gtgttacttt
    13261 actatggaag atacattatt atttggttca ttagggctgg ctattttacg acacgcagat
    13321 cgcgtaaaga ttagttgtca atcattgtta gtaaacacaa tacctttaat actgacagat
    13381 gctaaaggac aagcatggag gaatccaact tattatgtga tgcaacactt atcgaaatat
    13441 gctaaaggtc aagtattgaa acaacaaatc atttgccctg tttatgattg tgaaaagata
    13501 aaaaatgttc cttatgtgga cagtgtgatc gtagataacg gcaatcagct gactattttc
    13561 ttgatcaatc gcacaaatga acaacaaaag ataacgattg aacatgattt caatttgcta
    13621 gatcaaggag agcactacac attaaccagt agcgatctgt tggacaaaaa tacacgtgaa
    13681 gaaccagaaa aaataaaacc tgaaataaac tatttttcaa tagaaaaaca tgacgaatta
    13741 aatgtaggga tagaaaaata ctcttggaat gtaattagaa taaagaaaat gtgaggaaat
    13801 ttgttatgat gaagacactt tataataatc ctatcgttcg gcaacgggca gatccttggg
    13861 tatataaaca tacagatggt tattattatt ttacaggatc ggttccaggc taccaagtga
    13921 ttgaattaag aagggcaaag tcactgaatg aattagaaca tgctgcaagc ctgattgtat
    13981 ggcaggctca tgaagaagga ccgatgagtg aattgatctg ggcacctgaa gtccattata
    14041 tcaatggaaa atggtatatt tactttgctg caagcaatca taaaactata cgtgatgaat
    14101 ctcatcatca ccgcatgttc gtacttgaaa atcagcatat agatccaatg aatacagatt
    14161 ggatagaaaa gggacaaata aaaacgaaaa gggaaacttt cagtttagac ggaacaactt
    14221 tctcttctca aggaaagcta tattatgtgt gggcccaaca agatcctgaa attactggga
    14281 attctaatct ttatctatcc gaaatggata atccttggac gttaaagggg aagcagatcc
    14341 tcctttctat acctgagtat gaatgggaaa aacggggttt ttcagtaaat gaaggtccag
    14401 cagtccttac tcgcaatggg aaaatattca ttacgtattc tggtagtgca acagatgaaa
    14461 actatgccat gggcctgctg tgggctgatg agcacaagaa tcttttatta aaagaatcat
    14521 ggcataaatt atcggagcca gtattcgttt cttctgaaaa aaataagcaa tttggtcctg
    14581 gtcacaactc gtttacggtt tcagaagacg ggtgctttga tattttgatc tatcatgctc
    14641 gaccagagaa gaaccaaaaa ggggatccgt tagacaatcc taatcggcac gcgaacgcgc
    14701 aatgctttac gtggaatgag caaggatttc cagaatttgg tgaacctgtt ccgtatgcct
    14761 tatgagcaca agaaaccttg atttttgctt gaataaacct tgcagactcg ttatgatata
    14821 tgtacgtaca aataaaaagg ggcaaggcaa atggcaaaat atcaagatat tgcagaagag
    14881 ataaaacaaa agatccttcg tgaggaatac gaagtaaata caaccattcc ctcagaattc
    14941 aagctgcaag aaatatatga cgtcagcaga catacgattc ggcaagcaat cgctgtgttg
    15001 gtaaatgagg gctatctgcg taaagaaaaa gggtcgggca catatgtaga tgacagctat
    15061 aagaaagaaa aaacaccatt gaacagaaca aaaacgatcg gtgtcatcac cacatatctc
    15121 tctgattata tttttccgtc gattatccga ggaatcgaaa atgaattacg agaatctggg
    15181 tattcattgc ttttagccag tacgaataac gatcacgaat tggagaaaga gtgtttgaag
    15241 aaaatgattg cttatggggt agatggtttg atcgttgagc ctacgaaaag taatcagtat
    15301 aacccaaact tagcacttta tgttgctttg agagaacaag gcattccgat ggtgatgatc
    15361 aatgctgctt atgaagagtt aaatgcctct tatatttgtt tagatgatgt gaaagtcggt
    15421 tttatggcag cagaatattt gataaaaaaa ggacatcagc gtctgttgtt catcacaaaa
    15481 atcgacgatc ttcaaggaaa atacaggatg aaaggtttta tcagcgcgtg tgaacagtat
    15541 aatgtgcgtt ttttgacgga agatatcatt actttcacca cggaaacacg agaaacaatc
    15601 gctgaaaaaa cagtacaacg gttgaaagaa gaacaagctt tagatggcat catttgctat
    15661 aacgatcaaa tagctagttt aatgctagat aagttgacag aaaatggcta tcatattcca
    15721 gatgacctat cgatcgtagg aacagacgat tcttctttaa gccatttagg gaataaaaaa
    15781 ttgacaacat tgacgcatcc aaaagaaaag ttgggacaag atgccgcacg gtggatcgtc
    15841 acaacgattg aaaaaggaca ggcacagcca aatattctct atgaacctgt actagttgaa
    15901 cgggaaacag tgaaagaaaa cgaaaaataa gagacgggtt tttaccgcct cttattgctc
    15961 ctacggttac tcgtcgcaat gtttgtgaga gcttttgtca tcgctcaagg ctgaacgttt
    16021 ctttcaccac ctctccacta aacggtgttc tcctaccaac tggtcacaag tcacaatatt
    16081 catcaaacat gagaagctgt tttttgaaat tgttccttgt gactggaaac taagcggttc
    16141 cttcttattt cttgaagctg accacttctg tcacaacctc tttaagaatg atggatagaa
    16201 atacgtttag gataagtttt tttagatgca ctttgttcga tttcctctaa agatttccca
    16261 cgagtttctg gtacgatctc ttgaataaat aaaaccccta aaaagcagat gatcccaaaa
    16321 atgccgaaaa cgatttcttg agacatagaa gcagtcatca caggaaaaag caagccaact
    16381 aggaaagaac caatccaatt aaaagaagag gctaggccag atgctcgccc gcggacagct
    16441 agtgggaata tttcgcctac gattacccat gtcagtggag cccatgtgca agaataaaat
    16501 gcgacataaa tacataaaaa caagagaatc aacaacgaat ttgtatgagc atccagtaca
    16561 gttcctaaaa cagctggtag gatgaaagaa agtcccatca cgctaccgcc tattttcaat
    16621 aaagttcgcc gattgaactt gtctgcaata accaaaaaga gcaaagaacc agcaactaaa
    16681 atgattcctt ggatgatcgg ccacatcaat gcatcgctcg ctgcatgccc agtcgctttt
    16741 tctacgatca gcggaatata gtaaaaaata gcattagctc cttgaaattg ctggaatact
    16801 gctacaccaa taccggcaat gactaaggaa cgatattttt ctaaaaacaa agtatgccaa
    16861 gaagttccgg ttgtcttttc ttgtttgaca ttcagctgga tttgttcgaa ttcctgttca
    16921 gcttcttttg gtgtccgaat atagttcaat actctttttg cctcttccaa gcggccagat
    16981 tgcataagaa aacgcggtga ctctggtaga gctaaaacac cgaaaaataa aatcagcgcg
    17041 gggacagcag cgagccctaa catcacgcgc caagccatcg tttcaggcaa cccttttagc
    17101 aaataatctg caacatagga aaggagcatg ccagaagcaa tcatcacttg attgatccct
    17161 gacaatcttc cccttagtct agcaggagcc atttcagaca tataagcagg aactagggca
    17221 gatgcagcgc caacagctaa acctagaaga atccttgctg caatcagaaa ataagaacca
    17281 ttgtgagggg cagatgcaga aaggacagaa ccagccataa aaataagtgc agaaagaaga
    17341 atcatttttc gtcgtccaag cttatcagaa agaagaccag ataaagagcc gccaaggatc
    17401 gcacctaaca tgaccgaaga cgtgatccat cctatcaaag aagctttacc tgccaaaccc
    17461 caatcatgct gtaaaaaagg taaggcgccg gtcataacac caatatcata tccaaataga
    17521 atgccgccaa atgcgccaaa aaaataaata aacgatgagg aaactttttt ttcttttttc
    17581 ataagtattc tctccttcta gaatttcgag aaggcggttg atcagatttt gtaagcaatt
    17641 tcattttata acttatgtac gtacaaaaca agtgtttttt attgtattct tgtaaataac
    17701 tgcttgacat gtacgtacaa aagtatacaa taatcattgt aagcgctact aaaaagacgg
    17761 tttgatcagg tttgacgaga aggagggagt taaatcatta tgaaggaagt aaatgcgcaa
    17821 agtatgttag atgtcataga tggtcgtaca tctttaggga ttgagtttgg atcaactagg
    17881 atcaaagctg tattgattga ttcatctttt actcctattg ccgctggtag ttatgagtgg
    17941 gaaaacaaac tagaaaatgg tatctggacc tattcattag aagatatttg gaaaggactg
    18001 cgcgtcagtt accgaaaaat ggcagcagaa gtattcgaaa tctatggcga gaatcttacg
    18061 acaatcgggt cgattgggtt cagtgcaatg atgcacggtt atctagcatt tgatagcaag
    18121 gaacagttac tagtaccatt tcgtacttgg cgaaatacaa tcactgaaga agcagaacga
    18181 atattaacgg aaaaatttca atacaatatt ccgcagagat ggagtatcgc tcatttgtat
    18241 caatctattt tgaataaaga agaacatgtg aaagaaatta attttttgac aacgcttgca
    18301 ggttatgtcc attggcagct tactggtgag aaagtactag gcgtaggaga tgcatcaggc
    18361 atgtttccta tcgatccttc aacgaaaacc taccatcaag aaatgaaaaa tatttttggt
    18421 cagttaatcg aaaaagcgca cgtagcgatt gacttggatc acattttgcc taaagttcta
    18481 gtagcaggag aagaagctgg caagttaagc gaatcagggg cttatctgat cgaccctacg
    18541 ggaaatttga gaccaggaat cccggtttgt ccgccagaag gggatgcagg aaccggtatg
    18601 gtcgctacga acagtgtagc caaagggaca gggaacattt cggctggtac ttccgccttc
    18661 gctatgatcg tattagaaaa agaactagaa aatgtccatc cggaaatcga catggtcact
    18721 acaccttcag gagaactagt aggcatggtt catacgaata actgctcttc ggatatcaat
    18781 gcttgggtca gtatttttga agaatttacc aattctttgg gtatggagat aagcagagat
    18841 aaattattca cggtattatt caacaaagcg ctagaaggcg atacggattg cgggggatta
    18901 ctttcttatg gttatttttc cggtgaaaac attacaggag taaatgaagg aaggccatta
    18961 tttgtacgta caccaggtag ccgttttgat ttagcgaatt tcatgcggat ccatttagcc
    19021 agtgcttttg gtgcaatgag aatcggaatg gatatattga aatctgagaa tgtccaaatt
    19081 gatcgtttag tggggcatgg ggggattttt aaaacaccag aagttggaca gcggattcta
    19141 gcatctgcta tggaggcacc agttacagtg atggacacag ccggagaagg tggagcgtgg
    19201 ggaatcgcgt tattagcagc ctatatgatg gatcgacatg ggaagtcttt agaaaacttc
    19261 ttggcagaag acgtgtttgg acaagaccaa ggaatcacca tcacaccttc agcagaagaa
    19321 atagcaggct atcagatatt tatgagacgt taccgtgagg ggatcgacat tgaaaaaaca
    19381 gcgattcatc aattgcaaga aaaaggagtg atagaaaatg ctggaacaac tgaaagaaga
    19441 agtataccaa gcaaatcttg acttgcctaa acacggactc gtcaaatata catggggaaa
    19501 tgtgagcgct tttgatcctg aaacacgata tttcgttatc aaacctagcg gagtcagtta
    19561 tgaagagatg acagcagacg acatggtcgt tgtggacttg gacaatcata tcattgaagg
    19621 taaactcaat ccctcttcgg atacgcctac tcatgctgtt ttatatcgtt catttcctca
    19681 aatcggagga atcgtccata ctcactcgac atgggcgacg atctgggcac aagcaggatt
    19741 ggatgttcct gcgatgggga cgacgcatgc agatactttt tatggatcgg taccttgtgc
    19801 tcgatttttg acacaacagg aaatcgacag cgggtacgaa tatgaaacag gaaaagttat
    19861 catagaaaca ttcaaagaac gcaaaattga tcccttagca attccagggg tacttttaca
    19921 cggacacggt ccatttactt gggggaaaga tgcgcaaagt gcggtaatga acgcagtcgt
    19981 actagatgaa gtatgcaaga tgaatttatt taccagacag ctcaattcat tttcagaaga
    20041 gctgcctcaa cggattttag ataaacatta tttacgaaaa cacggaaaaa atgcgtatta
    20101 cggacaaaac aaataaaagg agtggctaat tatgttgaat attggagaaa aagaattttg
    20161 gtttgttgta ggatcacagc atttatatgg ggaagaagca ctgcgagaag taaagaaaca
    20221 tgcacaagaa atggtcgatg aactgaatga aaatggccaa ttgccttatc caatccgcct
    20281 tcaagaatta gcagttactg ctgatacgat cacaaaaatc atgaaagagg tcaattatcg
    20341 agaagaagta gcaggtgtga tcacttggat gcatactttc tcaccagcaa aaatgtggat
    20401 ccgcgggaca aagcttctac aaaaaccatt gcttcattta gctacgcaat ataacgaaag
    20461 cattccttgg aaaacgatcg atatggattt catgaattta aatcaatccg ctcatggtga
    20521 ccgcgaatat gggttcatca atgctcgatt aaataaacaa aataaaatcg tcgttggcta
    20581 ctggaaacga cctgagatcc aaaaagagat tgctgattgg atggatgttg cagtagccta
    20641 taatgaaagt tttggaataa aagtggctcg ttttggtgac aacatgagaa acgtgggtgt
    20701 cacagaagga gacaaagtgg aagcacagat tcaatttggt tggactgttg attattttgg
    20761 tatcggagat cttgtacaag taatcgatcg cgtatcagac gaagaagtcg atcaattatt
    20821 tgaagagtac aaggaattgt ataccttcga ctatggtgat tatgaagaaa agacatggga
    20881 ggaacatgta aaagtacaag ctcagcagga aatcggtatt cgccgtttct tagaagaagg
    20941 aggctataac gcttttacga ctaattttga agacctgtat ggaatgaaac aactacctgg
    21001 actagctgta caacgtttga tggcagaagg atacggtttt gctggggaag gcgactggaa
    21061 aactgcagcg attgatcggt tgctgaaaat catggctcga gggaaagata caggattcat
    21121 ggaagattat acttacgagc tagctagtgg ccaagaagca atcttggaat cccatatgat
    21181 ggaagtagat ccgacgcttg ctgcgacgaa accaagaatc gttgtttctc ctttatcaat
    21241 gggagataga gaagatccgg cgcgtcttgt atttgatggg aaagcaggag aaggggtagt
    21301 cgtatcgatg gcagatttcg gtacgcatta taaactgctg atcaatgaag tagaagcctt
    21361 tgaaccaacg actgaagcac ctaatttacc tgttgcacgt gtgttatgga aaactaaacc
    21421 gaatttccat gaaggtgtcc attcatggat tcaggcaggt ggcggtcatc ataccgttgt
    21481 ctcgctaaat ctaacaacag atcaaattga aacgtgggca aaattagttg agttggaaac
    21541 agtggttatt agataaaaag aggttgtgaa aaagccactt agttttaaga aataagaaga
    21601 gattgacgaa atttgctttt caactttttt gaaatttagt cttattatca atgtcagcta
    21661 acggaacacc atttatcaag atatctcacc ctcaatattt tgctctcgaa aataaggctt
    21721 atggcagtaa cttgtcatag ccttattttt atcactcagc ctactctgct ctaactgctc
    21781 tttttgcttc taggaagtca aatggtaaac agttgtctaa ttgcagaaat ttcgagatac
    21841 ttgttagtaa ggagggggtt ttatgtatca cgttcatttg attgatgcta ttccagaaca
    21901 agagatagaa aagttacaag gggaatattt caaaataata gatgatttgc cagccgaagg
    21961 aatagttatt cgtagtacga aagtgaaaga tgaatggctt acaccagatt tgctagcaat
    22021 ttcaagagct ggtgttgggg tgaacacgat caacgttgaa aaagcttctg aaaacgggac
    22081 gatcgtcatg aatacaccag gtgtaaatgc taatgcagta aaagagcttg ttttgtgctg
    22141 tttgctctta tcttcccgtc cgataatcga agcaagtcgt atggtacaaa cactaacagg
    22201 tcctaatatt ttagaacagg cagaaaacaa aagaagtgct tatgtgggac gagaattgca
    22261 aggcaaaacc atcggtcttc ttggtcttgg agcgataggc acaaaagtag cgctaagttg
    22321 ctatagctta gggatggatg tcttgggtta ttctatccgc gatgcccagt tggattatgt
    22381 tcggcaagca gatttagaaa cagttctttc tacctcggat tacatcgtag tcatgctgcc
    22441 gttgacagaa gatacaaaag gattgatcga tcaggcgaat atagaaaaaa tgaaaaaaga
    22501 tgctgtactt atcaatgtag gaagaagtga aattgttgat aaatatgctg ttatgcaagc
    22561 attggaaaaa caacatctgg ctaaatactt gactgatttt ccagaagaag agttcttaga
    22621 aaatgaccgt atacttatgt tgcctcatct agggggatcg actcaggaag ctttggcaga
    22681 cagcggacgt ttggcagttg aagccttaaa agattatctt ttgttcggta cggttagaga
    22741 agcggtcaat tatccatccg cacgaatgtt tttccaagcg ccgtttcgat tcactatatt
    22801 ttatcaaaag aaaaccaata tattagcaga gatattttct ctgctgaatg agaacgagct
    22861 agcgatcgca gatatatcgc gtaaccataa gaatgagcat gtctacatat tgattgacat
    22921 agacagtact gattttgaac agctcaatca agtgaaacaa cagctagaaa aaatttctgg
    22981 agtacgaaag gtccgcttat taaagaaacc agaaaggcca taaagaaaga gaatatttgg
    23041 atttcattaa ttcttctttc cgttctttac tttcgaattt cgtacaacta aaataagaga
    23101 agcaacattc ttttattgat agaaatgaag gagcaagcat ttgaaaagat atataagcag
    23161 actttcgacc aaacagaaaa agattttaaa aggaacagca gcaatcatca gtatcttttt
    23221 tcttgttgtt tttagtaatt tatttttgca gtggtgtcaa aatgatctat ccgtagacct
    23281 tgcgttgaaa tttgcttttt cttggcatac ggaaaaattc ttcttagcct gtctcgtctt
    23341 gctgattatt cttatttttc tgattgcact agcaggatct gtccctttag gttcccttac
    23401 gtatgtcgta gccatcggtg tattaggttt tgcaaattat atgaaaatga gttatcggca
    23461 agaaccgatt tatccagacg atttgaagat gatcactgaa atcggattgc tgaaagatat
    23521 gaccggcact atgctgttta cagtgatctt agctgccgca ggaaccgtga taggattgtt
    23581 ttgctggtac atgtttcgaa gcctgaaaaa aggaaggcga ttccaattga tccgattaac
    23641 gacactgctt gtggcaattg gactgctagg gtatatcagt aatttcaaca atcccgataa
    23701 tttgttgcga aaagcatata ataaaacggc actatggata ccttacagcc agaaaatgaa
    23761 ctactataac actggtttta tcggtgggtt tttgtacaat ctgaaggtag aaccaatgga
    23821 tgaacctgaa ggatattcga aagaaaagat caaagaaatc actgaaaaat accagaagct
    23881 agccgatgaa aaaaataaaa ctgtagagga agagtcgccg aacatcgtgt tcgtgatgag
    23941 tgaaagtttc tcagatccta gtcgattaaa cggcgtagaa gtatctggtg agccattggc
    24001 agattattat gaagtagctg atcaaacata tagtggcaat atgctttctc aaaactatgg
    24061 cggtggaaca gcaaatatcg aatttgaagc attgactggt ttttctatgg cgttatttaa
    24121 tgcgcaactc accacccctt acacgatgct tgtaccaaaa atggatcagc ttccttctat
    24181 cgtttcagcg ttaaacgcac aatcatacca gacgacagcg atccatccat acaatacttc
    24241 gatgtataaa agagaggatg tttatcagac attaggattt gaccagttca tcagcgagcg
    24301 tacgatgacc tatacggata cgatagagaa taatccatat atttctgatg agtcagctta
    24361 caaagaagta atgacacttc tcaaggaaga aaaaacacct cagttcattc atttagtcac
    24421 gatgcagaca catatgccct acgatggaaa gtatgataat ctagactatc ctgcaaaaac
    24481 ttcagatgga agtgggacac ttgacttaga gaattatctg caagatattt cctatagcag
    24541 cacggcactg aagcagttca cggaagaatt gaagaatctt tctagaagga ctttagttgt
    24601 tttttggggg gatcatcttc cagggatcta ttcagatacg atccaagcaa aaaatgacaa
    24661 acaaacattg catgaaacac aatttcttat gttcgacagt aaaggagaat tagaaaagca
    24721 aacgactcac gatgcaatca ccagtccgtt ttattttgca gcgaatctaa tggaacagac
    24781 gaatcagaca acaaatggct tttatcagct gcttttatca ttagaacagg aacttccggc
    24841 gtttgaacga gaactgtact atcaaaacgg acagtggtat aaagaagcgc aattcaatcg
    24901 ctcgcaacaa gagatttacg acgaatatca attgatccaa tatgacattg tcgcagggaa
    24961 acaatatagt ttagcagatg gtttctttga gcacgaataa gaatggcgag ctgtatagaa
    25021 accattaaat tttttcaagt acttgtcatt tgaggataaa aacaagtaga ataaataata
    25081 acaacaatgg agaaagtagg aaaacgaaca tgttaccgaa tattggctat tatgtgcagt
    25141 ccatcgatca aatcgtcaag gaaacagaag caatcggaga aggaatgcat ccgaaatatg
    25201 aagtgatcag aaacgcaatt gatgaaggaa aaacaagtga actggacaaa tcgactcttg
    25261 aagagatcat cctgttattt gaagaaggaa caaaaaaata tcgggcaatg cttatgaaag
    25321 tcagtacttt gcgtccacca gcaaaagcaa tgggcattca taaaaatttt gaaaaagctt
    25381 atctttcata tgtagcaggc tgtgaagaaa tgatccaaag tatcgatctt gaatcagggg
    25441 tagatgaaga tctattcaat acatctgaag caaaacaaga ccaagcgaca gaccaattga
    25501 cagctgccat ccaaaaaatg actaatttgt tgttgaaaaa ataaaagaaa tctttgataa
    25561 caataaaaac tagagttatc taatataaat gtaatattac ctttatgata gagtgatcaa
    25621 aatcctttat gataatgaca tacctataac caacaacaac cttgtactta ctcaaaatcg
    25681 agtaaatact ccttttccgt cgagtctaac catctcggcg gttttttatt tgtagaaaag
    25741 aacatcagga tagacggaaa agtcttgtcc tgatgttctt ttcagatagt atggaaagct
    25801 gattagtttt ctacattctg tacatattgt tcaaagtagt tctgtaaatc ggctttgagt
    25861 ttctgatatt cctcttcgct atactcttta tcttcgattt tcccatcaaa gaaaggaata
    25921 tttagttctt cccgtagtct gtctaatacg tcttgctgat tcatttcatt ctccttttct
    25981 tactaacgat caaaataaac acagacacat tctggtacat agacatcttt tttcagtaat
    26041 tccagtaatc ctgtttcagg atgacggcga tataatgtca gattatcggt gttctgattg
    26101 gcacacacga caaaattatt gcttggatct agtgcgaaat cgcggggaaa atccccttct
    26161 gttgagatga tttgcttgtt ttgaatgtgg gaaccatctt caaaaactgc gaatacagca
    26221 atcgagttat gtcctcggtt agaagcataa aggaacttgc catcatttga aatgcggata
    26281 gctgcccctc cattttcacc gtcgaattct tctggcaagg tcgatatttt ctgtaattct
    26341 tcaaaagcac ctgtttcttt attataagaa agcacgcgga ctgtgctgtc taattcacca
    26401 aataaataag cgaattgtcc atttggatga aagacaagat ggcgagggcc tgttcctggc
    26461 tctgcagtga aggtagttac aagattcaat ttgccgtttt cggacacatc ataagtatac
    26521 acacgatctg taccaagatc acatacgact aatcgttggt caggagtcag atccgtatag
    26581 tggacatgcg catgatcttg gtttttatga ggacctgtcg cttcttgatg gaatattgaa
    26641 tctgctgctt tcagttcgcc atctcctaat atatggtaga catttacttc acctttatga
    26701 tagttcgccc cgtatagtaa ttgacgtgct tcatcaaccg ctacataaca caaaggagcg
    26761 ccagactctg ttaccgcatt caaaaaatga aaatccttat cgtacgcacc ggcaccacct
    26821 aatccatcca cactagtaac tgtgtaaaga ttgccagctt tactttttgc tacataggta
    26881 gggctatttt cttcaacagc taatgaaagg ttggctaatt cttctttttc tgtatcaagg
    26941 tcgatcgtat agattccttt actttcgcga cgcgtatagg ttcctaaaat tatcttttcg
    27001 atcatatgag ctgattcctc ctaattgtaa tgaaatagtt ttcgttttta ttctatcaca
    27061 taattattcc acacggctaa agaatgagaa tgtgttatac tgtttttgaa agcaattaaa
    27121 ggagagagtg caatgattca ggcaaagatt acagaaattg ggacagaagc aataaacaag
    27181 gaagaaccca tgctgatttt gttcgataaa acagcaacag ctgccttacg aaaatattcg
    27241 gtgattcaag aagtatcaaa agacgaacct ttttctttga aagcaggcgg aacaattgct
    27301 tttgatgatc aggtatatac gatcgattat gtcggtccga tggccaatgg gaatttaaag
    27361 acagtagctc acgtatcatt gatttttgat gcttgtccag aagaaggaca aattgcaaat
    27421 ggaatctatc ttcatccgca tagactgcct gctattggtt tgggaagcca aattttttat
    27481 aactaacagg aggaattatg gaaggaaaaa ataagaagaa cagaccggta tcgtggtttt
    27541 ggcgctggtt tttaaataat caagtagtca cagccttact tgttgtattg ttaatattgc
    27601 tgatcgtctt tttatttaca aaagtttcat atttgtttgc accaatctgg caatttttag
    27661 caatcgtagg tctgcctatc attttagcag gaatcttgta ttacttgatg aatccggtag
    27721 ttgattactt tgaaaagcga aaagtaccaa ggctttacag tatcattggg ctgtttgttt
    27781 tggttgttgc actaatcgca tgggggagcg tagtgatcat ccctaagatt caggaacaaa
    27841 cagtgagctt catcagtaac ttccctcaat atgtagatac gattgataat aaattaaccg
    27901 agattttgcg ggacccgctg ttcaaccaat ttcgcgaaca gttggaaaca gcaggtgata
    27961 agttcatgaa ttcggcaggc gatatgatcc aagatatatc taagagtaca gttcagagtc
    28021 ttggaagttt tgtcggcgcg gtagcgacta ttttagtggc tctgctgacg atgccgttta
    28081 tcttatttta tctattgaaa gacggtaaac aattagcacc ttattttgtc aaatttttac
    28141 cgacacgcat gcaaaaaccg acgttgaatg tgctgagtga aatgaatagt caagtttctt
    28201 cttatataag aggacaacta actgtggctt ttgctgtggc aatcatgttt atgattggtt
    28261 ttgcggtcat tggtttagag tatgctgtca cgttggggat tattgcgggt tttttaaacc
    28321 tgatccctta cttaggatca tttttagcga tgattccggc tatcttttta gccattgtag
    28381 caggtccatt catgatcatc aaagtactga tcgtttttgc agtagagcag acaatagaag
    28441 gacgcttgat ctctccatta gtactaggga atcagttagc aatccatcca gtaacgattt
    28501 tattagttct gctgacttct gggaaattgt tcggaatcat cggtgtgatc ttggggattc
    28561 ctgtttatgc agcagctaaa gtagtgatta ctcatgtttt tgaatggtac acaacaatct
    28621 cttctcttta tgaagaaaat ccgttgaaaa agcagaaaga ataacaaaaa gagacagatg
    28681 ggaaaatatc caaggcacaa atgctgcttt gaagattttt tcctctgtct cttttgtatg
    28741 catttatctc aatttttaaa atgatttacc taaagcagca gctttatcta atgcattttg
    28801 catcaactca tctgcacggt cagggtcata atcgattcct tcgatgaata gctgatctac
    28861 ttgatcgatg cctacaaagt ttaaaatacc ttttacatat tgagaggcaa agtcttgtcc
    28921 gttgtataca ccgccattag attggatgtg cagtgctttt ttacctgtca ctaatccttc
    28981 tggcccgttt tctgtatagc ggaacgtttt tccagctaca ttgacggtat cgaaccaagc
    29041 ttttaatttt gttgggatat ttagattcca taaggcgttt gcgataacga ttttatcagc
    29101 agcaaggaac tgatcagtca attcattgaa acgagcaatt ttttgttgtt gactttctga
    29161 taaggaagtg aattctgcac cagcacgtaa tgcttcccaa cctgataata attcttcatc
    29221 gatttccgga atatcatcgc gataaagttc caaaacagtc acttcatcat ctggatgatt
    29281 ttctttataa cttgttaaaa aagacgtcaa tgccttaact gtgcgcgatt cttctgcagt
    29341 taggggatga cctttgacta ctaaaacaga tgccatatgc ttaccttctc cttttattgc
    29401 tatgattgtt ataactatga ctaacaaaat cagtttactc gaaaaagaaa aggctatcaa
    29461 gtcatattga taaggttgaa gaataaataa ctaaaaaaag acagggtata aaagaggctg
    29521 tgacacgatt ttttgtcaca gcctcttttg aatctaacaa gcaatattca agcaacactc
    29581 gactgaagag cttccatccc accaatgata taaacagcac gaaaaccatt agcagtaagt
    29641 tgatcggcta atgcttctga tcgcctgcct gtatagctta gaatataata aagtttcttt
    29701 ggatctagat tttttaattg tcttggcaag atagcagcgg ggatagaaag cgagtggctt
    29761 aagtggtttt ttgtgtaatc taaggtattt cttgtatcta aaacgatgct gtcagcatcg
    29821 agaggcaatt tattgaagtc ttggacacta attgattggg ccatttatct catcctttgt
    29881 ttagtatgtg gctattttaa tgggcaactc tcattaattc aaatggaagg attcctctta
    29941 tcactttttt aatgtatcgg atgataatga aaaaaactat gcaaatgtct tgcaaaacag
    30001 gtaggaggtg ttataatgac atagcgtcat atgacaatgt gtcatcttga aagaaaggag
    30061 aatccatatg ccgacacaga catttttcca tttgcctaaa gaaaaacaaa aaagactaat
    30121 cgaggctgcg agaatcgagt tttctagagt acccttaaaa gaagcttcga ttgctaatat
    30181 cgtcaaatta gcggatatcc ctagaggcag tttctatcag tattttgaag ataaagagga
    30241 tctttatttt tattactttg agacaatgag acgtgacagc tctaaagata tgttacaact
    30301 aatgaaagaa tccgatggtg atctattcaa aggattcgaa tcctattttt ctaaaatgat
    30361 ttatgagatt ttggaaggcg agaatgcttc tttttatcgt aacttgttta tgaacatgga
    30421 ttaccgtgcc tcaagaaaag tcgctcctca tacgagtcgc caaaaaacgc ctcacgatcc
    30481 acataaagaa cacaaacaag atgcaaaaga gttgcttgaa ttgatcgatc ggacgaagct
    30541 gaaagtaaaa aatgatcatg aattggaatt actgatccaa ttagtgatga atactgtatt
    30601 tacaacaatt gcgcattcgt atcgcttatt ttcaacatct gaagattact cagtagagca
    30661 agcaatcagt gaattcaatt tgaaactttc ttggctgaaa aacggagtat ataaatagaa
    30721 agaagggaac tagatgctaa aaatcgtaaa acggatctcc ttgacttcag caattgcagc
    30781 tgcagttttc atggtgatcc aagtactggc agatttatat ttgccgacac ttacctccaa
    30841 tattattgat aaaggggtag cgcaaggaga tgtcgattat atttggcata caggttttgt
    30901 gatgatcggc ttttctttga tcagtatctt agctgctatc gcaaatacat tttttgctac
    30961 tcgtgaatca cagaaactgg gtaagcaatt gcgtacggat gtctataaaa aatcagagag
    31021 tctgacaaaa gatgcgtttg ataaatatgg aacggcctct ttgatcacaa gaacgaccaa
    31081 tgatgtgact caaatccaaa tggttacaca aatgttttta cgtatgatga tcaatgcacc
    31141 aatcacgttg attggcgcga gcatacttgc ttatcaaaaa gatcatcagt tgacaaaaat
    31201 cttcttagtt gtcatcccag taatgattat tttgatcggc ggaatcatgt actttgctgt
    31261 tccattattc aaaagtatgc aaaagaaaac tgaccgttta aacctggtat ttcgagaagg
    31321 attgacaggg gtcagagtga ttcgagcatt cgataagaca cgctttgaag aaaatcgttt
    31381 tgatttagcg aataaagatt atacaaatac ggcaatcaaa gttaatacga tcgtcgcatt
    31441 gatgatgcca atgatgacat tgatcatgag cggtacaaac gtagcaatca cttggtttgg
    31501 tggacactac atagcagata tgactttgga agtcggtaat ctgattgcat ttatgactta
    31561 tgcgatgcag atcttgatca gctttatgat gctttccgct atttttatca tggtgcctcg
    31621 tgcacaagct tcagctgacc gtattaatga agtgttggat gaaaaaatcg gtatccatga
    31681 ccctgaaaat cctaaaacag tttcttttgc tggaaaaaac gcaacattgg ccttcaatca
    31741 tgtcaattat cgatatcatg gagcagaaaa acttgcattg gaagatattg atttccaagc
    31801 caagtcgggc gagatcgtcg caatcatagg ggggactggt tcaggtaaaa cgaccttagt
    31861 caatttgatc cctcgattat atgacatcga atctggttcg atccaaataa atggaacgga
    31921 cattagtgac atgactcaat ataatttgcg agaattaatg ggctttgttc ctcaaaaagc
    31981 agttctgttc tctggaacga tccgagacaa tatgcagtat ggtaagccgg atgcaacaga
    32041 tgaaatgatt tggaaagcat tagaaatcgc acaagctaaa gattttgttt cagagatgga
    32101 agatggctta gatagccatg tggaacaagg aggaggaaac ttctctggtg gacaaagaca
    32161 gcgtctggca attgcacggg cattagtcaa aacagcagat atctatgtgt ttgatgattc
    32221 cttctcagcg ttggatttca aaacggatgc caatcttcgc caagcattga aaacgaatat
    32281 gaaagaaagt atcaccgttt tagttgctca acgagtaagt acagtaatgg atgcagatat
    32341 gatccttgtg ctagatgaag gaaaactggt tggcaaagga acacatgaag aactattagc
    32401 aacaaacgaa acttatcaag aaatcgttca ttcacaacta agagaggagg acttagcatg
    32461 agtaaaacaa acacacgtcc ctctcatgga ccagcaggcg gtccaggaca tggtggacct
    32521 ggcagaaatc tcggtgtaaa aggtgaaaag cctaaaaatt tctggggaac ggtacgccga
    32581 ttgtttggct atatgtctaa acgtatggtt gcgatcatcg ctgtatttgt actagcaata
    32641 gcagccgtga tcttccaaat ccaaacacca aaggtcttgg ggaaagcaac cacagaaata
    32701 ttcaaaggtg taatggctgg cgctcaacag atgcaacaag gccaacaagt aacaaaattt
    32761 ccgatagact ttgataaaat cgcgcagatc attgcgacag taatcgtgat gtatttgatt
    32821 tctgctgtat tcaacttttt acagcaattt attatgacac gtgtttccca acgaacagtt
    32881 tatgaattac gtcatgattt ggaagccaaa atgaatcgtg taccgatttc ctattatgat
    32941 acacatacaa atggggatat catgtctcga gcaatcaatg atatggataa catcgcaagc
    33001 acgctgcagc aaaatttgac tcaatttgta actagtgcag tcacattgat tggggtcatc
    33061 gtgatgatgc tttcaatcag ctggcaattg acgttagtcg cgttattgat gatcccttta
    33121 agcttgatca tcgtgatgat cgtagcgccg aaatcacaag tgtttttcgc agatcagcaa
    33181 aaaagtttag gtttattgaa taaccaagta gaagaaacat atggtggtca taccattgtt
    33241 aaaacattca atcatactga aaaagaccag gaagtatttg aaaaagaaaa tcagaatctg
    33301 tatgccgctg gttggaaagc tcaatttatt tcggcaatca tcatgccgtt gatgaatttc
    33361 gttaaaaatc taggctatgt gttcgtcgct gtactaggcg gagtaaaagt tgcaaatggg
    33421 aacatgacat taggggatgt tcaagcgttc ttgcaatata caacacagtt ctctcaacca
    33481 atcactcaac ttgcaagttt gatgaacact atccaatcaa cagttgcttc agccgaacgg
    33541 gtatttgaag tgttggatga agaagagatg tccaatgaaa aatctggcct tccagaagaa
    33601 aaagatacac catacaaagt tcgttttgaa aatgttcaat tcggctacac accagataac
    33661 ttgctaatga ctgattttaa cttggatgtc aaacctggtg agatggtcgc tattgtaggt
    33721 ccgactggtg cagggaagac gacactgatc aaccttcttg aacggttcta cgatgtttct
    33781 ggaggtagta ttcgttacga tggtgtagat acccgtgatc tttcacgtga tgaattgcgc
    33841 gcacagtttt caatggtact gcaagatact tggctgttta caggaagtat ctatgacaat
    33901 atcaaatatg ggaacgacga tgcaacagac gaacaaatca ttgaggctgc taaagctgct
    33961 cacgtagacg attttgttcg taaattgcca gaaggatata acactgtatt aaacgaggat
    34021 gcaagcaata tttcgcaagg gcagcgtcag ctaatcacaa ttgcgcgggc attcttagca
    34081 aatccagatg tcctgatcct tgatgaagca acatctagtg tagatacacg aacagaaata
    34141 ctgattcaaa aagcgatgaa ccgcctattg gaaaaccgga caagtttcgt tgttgctcac
    34201 cgcttgtcta caatacgcga tgcagacaac attattgtga tgaatcatgg ttcgatcgta
    34261 gaaacaggaa accacgatac attgatggaa aaagacggat tctatgcaga tctttataac
    34321 agtcagtttt ctgaagaaga agcttcatag aatagtacaa atttattatt ttttttaggg
    34381 gctgtgacaa aagtcgtgtc acagtccctt tttccgaata aacggtgttc aatcagctgt
    34441 ccttcggtat tagctcaaaa aacggcaaaa tatgagaagc tatttttccg ttttgtatct
    34501 ctaatactca ggtcaaaccg ctgattttac aacctcttcc ttaaacggtg ttctcctgcc
    34561 aactcctcgg tcacaagtca caatagtcaa caaacctgag aagctgtttt ttgaaattgc
    34621 tccttgtgac tcggagttaa acggcaggct cacaacctct tggtaaacgg tgttcaaaag
    34681 ccagtttctc ggtattaagc caaatttatg caaaaatgta gaaagccatt ttcacaaaat
    34741 ttttcttact actcgaaact aagcgacttt ttcacaacct cttccttaaa cggtgttcaa
    34801 aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa taggaggagc tatttttgtt
    34861 tggctgttct tattacttga tgcagaacag ctttttcaca acctcttttt ataagagttt
    34921 ttactcatta atttacaaaa aacaagcaaa atgcgaattt tctcacattt tttttaacaa
    34981 aatcaaagtt attgcttgaa agaagaagaa tccatcgtta aaataaagct tgacgtagag
    35041 gggagcaaga aatatgaaag attttcaatt gggggctgcc acctatttaa aaagtgtagc
    35101 cattcgggtg aaagaccgag ataaaatgat tgatttttac aagaacgttg ttggctttga
    35161 tttgaaaaga gaagaaaacg aattagccat tttaggaaca gaagaagctg gaagtgaaat
    35221 gttgctgctg gaagaaagtc ctagagcgaa tgatcacatg ggggtgatca aaaagctgaa
    35281 ccgtttttca ttgattatcc ctagcacaga agaaatggca gatatccttt gtcgtatccg
    35341 taaaatgaat tatccaatca aagaagcttt agaagatcat ggacgtatgg ggattttgct
    35401 cgtagaccca gaagagaatg aattggaaat ttaccatgaa gagaataaga acgaccaaag
    35461 agaaattcca gaaacaatgg atcaagaagc attattaaga aaatctgaag aaaaattcag
    35521 taaactatca acaggttctt attttgaaaa aatccattta aatgttacta acttaacaaa
    35581 agaacgccaa tttcttaatc atgtacttgg tttgaaggta cataatgaag aagagggcat
    35641 ccatgtattg aatgaaggag atttccatgt tggtttgaca gaagctagcg gaggcgcaat
    35701 tgatttgcct acagatgaag tgattggact tgattttctg aaattcatga tcgatactga
    35761 aagcatggaa ggactgattg ctcacttgca gcaactatca gttgatttct tcttagacaa
    35821 aaagcacaca gtactcacaa tctatgatgc tataggaatc gaatggtggt tcgtcagtga
    35881 gccaaaagaa aagaataaaa ctgacattcg atgcgacgct taactttttc tttcttaacg
    35941 attgtcgcat gtctcgtcat tttatgaacg gtcatactat cgcttattct agagatagaa
    36001 agagaaaata gtataccggg ggaaactgcg cggtttttcg cgcagttttt ttgtgtaaaa
    36061 aaggttgatt cctcatagat taagctttaa gcttggactg taagaatctg atagaaaagc
    36121 aggagaaaaa gatgtatcca cacacgaaac agcttatttt gaaaaagatg gaagaaggat
    36181 tttatccagg tgtagcagtc gccttcataa aagaaaatca agtagaaaca tttacagccg
    36241 gctttgccca agtcgttcct gaaaagcagc tgatgacaga agatctgttg tttgatgcag
    36301 cctcactgac gaaagtcgtt gcaaccactt cattagtttt acgtctatta gaagatggaa
    36361 agatagaact cgatcaaccg cttcataaat atcttcctga atttgaaaat cagacaatca
    36421 ctttgcgtca tttactgaca catacttctg atatcaaaac atggatacca aacagagata
    36481 agctatctca ggaagaattg atcgccgctt atttgaagct agaaccaggt gagcaactag
    36541 gaaaagaagt aaaatataca gatgccggta cgattcttct tgggttgatg ctagaggaaa
    36601 tttaccaaga aactgcagtg gaaatctttc aagaacaagt attggaacca ttaggaatga
    36661 tgaacagctt atttcttcct tttccttcca aaaaaatcgt tcccacagaa caactgcctt
    36721 cgggtgaggt tttgcgtgga caaactcatg atccgaaagc aagagttttg gctgaacatg
    36781 caggtaacgc gggtctcttt attgatttga aagacagcat tacttttgtc caaatgtatt
    36841 tgaacaaggg aaaaatccgt aatggtcgtt ttttagaaga agagacgatt gattctttac
    36901 tgcaagatca aacaccgaaa aaaaatggct atcgttcttt aggatgggac ttaaaaaagg
    36961 atgtagaaga cggtcatgcg attctttttc atactggtta tacaggtacg tttttcttga
    37021 ttgatataaa aacacaagaa gcgttgatat ttttgtcaaa tcgcgtacat cctgtcgatc
    37081 atcgtgcgga gtatctcata tgtcgagatg aaattgttga aaactttttg aaagagaaag
    37141 cggtattacc gaaataatgc tataatagct atgaaaaatg agaggagttt gaattatgca
    37201 ggaacctatg tttttaaaac cagtttttca agaaaaaatt tggggaggaa gtcgtttacg
    37261 ttcagtcttt ggttttgata tccctaacga taaaatcgga gaagattggg cgatcagtgc
    37321 gcatcctcat ggtgtcagtg tagtagaaaa tggcgaattc aaagggaaaa gattagatga
    37381 actatggtca gaacacaagg aattgtttgg ccatccttca gaaccagtgt ttccattatt
    37441 gatcaagatc ttagacgcag aagatgatct atctgtacaa gtacatccag atgatgccta
    37501 tgggatgaaa catgaaggtg aattaggaaa aactgaatgc tggtatatca tcgatgctga
    37561 acctggtgca gaaatcatct atggtcatca tgcaaagaca agagaagaac tagctgagat
    37621 gatcaaagat gggcgctggg atgacctttt gaagaaagta ccagttaaaa aaggtgattt
    37681 cttttatgta ccaagcggaa cgatccatgc tattggtaaa ggaatcatga ttttagaaac
    37741 acagcaaagt tctgacacga cttaccgcgt gtatgactac gacagaaaag atgcgcaagg
    37801 acaaacaaga gagctgcata tccaacaatc gatcgatgta acaactgtcc ctgcgaaaac
    37861 accagaatta caaatcaaag aagtccgaaa agggaattca tcgatcgtca cttatttaga
    37921 aactgagttt ttcaatgtat atgagtggga tattaaagga atcacatctt tcaaaaaaca
    37981 agccccttat acattgatga cggtaatcga aggagcagga gaccttgtcg ttgacggaaa
    38041 aacatatcca ttagaaaaag gaacaagctg tattattcca aatggcgttt ctgagtgggc
    38101 ggtccaaggt gaactagcaa tcattgcgtc tgaaccaggc aaatagttcc cagatagctg
    38161 aaagcagcag acggtttttc gtttgctgct ttttctacat aaaatccgtc catcaataaa
    38221 tagaagtctg gtgaaaaaga tggaatacaa atggaaagca aacaacagca gtcgcgtgtc
    38281 tatgaaacaa ctgagaaaag ctggacatca cttaaatgaa atgatcatgc caaatctaag
    38341 tctgtttatc gcttggggaa tcttgtcatt agcaacaaaa ggtgtgtctg gcgatttgca
    38401 caccacatta gaagaggtat gccattggat gatccagctg cttttaccca tcttgatcag
    38461 ttattcaggc gggaaatcgg tagggggaca aaaaggggca gtcgccggtg caattgcttc
    38521 tttagggttg atcgctcgtt ccaatgctcc acaaatcgta ggagcgatga ttatcgggcc
    38581 gcttgccggc atcgtatatg aacaatttgt ttctagattc catgtgaaat tcaaggctgg
    38641 atatgaaatg cttgtcagca acctactagt aggactgact ggtagcgtta tttgtataat
    38701 tggaatcgtt tttattgaac cagttttaaa tagtgttcac ttgttgctcg cctccgttgt
    38761 gtcttggcta gtcacaatga atctgttacc acttgtcagt ctgatcttag aacctctaaa
    38821 agtactattt ttcaataatg caatcaatca tggtgtattg acacctttag gaatcgaatt
    38881 ctcacaaaca gtcgggtact cttccttatt tttgatggag gcaaatcctg gacctggttt
    38941 agggatctta ctttctatcc tttgttttgc agaaaaacag gaaaaagtaa atgcgagtgg
    39001 agcattgatg atccatgcga ttggcgggat tcacgaaatc tattttccat ttgtcttgct
    39061 gcgaccgtat ctatttttag ctgtaatggc tggtggggca agcggcacgt tgatatttca
    39121 atggttagat acgggattag ctgcacctgt atcgcctggg tcactactcg tgatttttgc
    39181 caatgcgcct tatccacaac tagctggggt aagtataggg atagcaatca gtacatttgt
    39241 gaccttcatt tgtgcagcga tactattgaa attaccaaat aaagaaaaag agaacaaaac
    39301 ggtcaaagaa aggggagaaa tcttggaacc atctatcatt cattccgtca tttttgcttg
    39361 cgactcaggt atgggatcaa gtgctatggg agccgccctg ctgaaaaaga aattagcagc
    39421 agaaaaaatc gatctttctg tcggatacag ctctatctat gaattgaata accaagtaaa
    39481 tcagctggtt atcgtgcaac atgaactagc gggtcttgca agagaaaaag tacctcaaag
    39541 tcaaatctat gtactggatc actttttgga aacagatatc ttgctgtcac gaataaaaga
    39601 agcgatccaa tttccaaagc gggaagaaaa aaaagagata gcagatatca cagaacaaaa
    39661 aacgtcgcct gctaatattg tatttttgta taaaaacaac agacgcggct cacaaactat
    39721 gggcatgacg attttaagtc aattagcaaa aaaagcgaaa aaacagtttg ttatctcaaa
    39781 agaatcaata gaaaaaatca aaatccaaga agaaacgatt tatatcgcac aaagagaact
    39841 agctgtaact gaacagctag aagaaaagat ccctcggcta gttctagttg aacattgggt
    39901 agctacgaat gaatacgaaa aactcgtgaa gggagaaata taagatgtat ttatcgccca
    39961 gagaaaaaca attattagca gaatttctca gtagcccgtc acctgtatct atccaaaaaa
    40021 tgatgaattt attgaaggtc agtaaacgga ctatttaccg cgaattagat aatcttgaag
    40081 tctcattgaa atcggtaaat gcttctttga aaaaagcagc tagaggctca tttgtcattg
    40141 aggcatcaga agaagtatta gagcaattaa aagaaaatac agatgggaaa agtaatgact
    40201 tatccactgc taaacgacaa cacgcgattt tagccgagtt gttactgacg acagagccgt
    40261 tgagtcttgc tcatttcatg gaatcatatc gcatcagtaa taccactttt tatgcagata
    40321 tcaaacagtt ggaagaaagt attcgccaac tgcctttgga aatcattcgg aaccagggat
    40381 acgagatcga aggaccggaa aaataccgcc ggcttctgac agcgaatgta ttagaattag
    40441 aaatcaatga atatgaactt tttcatagta tttctttcga tgcatcactg aattattttt
    40501 ttcgattcgt tgatccgcaa catctatctc ttgcacgcaa agtaatcggg gaagaattga
    40561 tccaaaaaaa gaccaatcta agtgatagaa agcttgaaca tttggttttg atgctgacat
    40621 tgacgatgga gcgtgtgacg aaaaatcatt tactgacaaa tgagacatat aatagtctgg
    40681 caaacaaaga attactacag acagctaaac gattgttttc acggatcgct tctgagacaa
    40741 aacaacttta tccagtaaat gagatcgtct tttttgcagg attattaaat gacttcacga
    40801 actcatttga tcagaatttc tttgaagaga cgttcgatac acagcttgct tatttagtaa
    40861 aacaactgat tcaagaagta agtgaagaga cgaatgtcca tttttatgaa gatgaaactt
    40921 tgtacaaaat gctgttgact catttatctg gtgtgttttc aagagccgtt ttacaagaag
    40981 agacactgac caatccgatt ttagaaaaaa tcatggttca atacgaggaa gttgcgaatg
    41041 caatccgtaa agcagtagag cggatttttc aagaaaaaaa attatccgaa gaagagatcg
    41101 cttatatggt ccttcatttt gcgaattcat tggaacgaag tccgaaagaa agcaatatca
    41161 gtattgcagg attttcgcca agtggattag cttctactag catgttggaa ctacgattga
    41221 aaaggtattt tcccttcatc caacaaattc atttctatcg gattgctgat ttaaaaaaaa
    41281 tcgatttaca agaagaatat gatgttgtta tttctacatc tattttacca ggatacggtg
    41341 gaaaatatat tttagtctcc ccgctactgc tagaagatga agtcaagcag ctaaaagaag
    41401 ctttttcgca tattgagaag aaaaaaaggc aaaaaattac gtataacagc aataacgagt
    41461 ggatgataga agatacttat gaggaaacaa tgcatttcat ggatcaaatc aatcaattac
    41521 tcggtcgttt ttttatccaa gaactggata atcctgagac gatttccgaa acgattcgca
    41581 gcttatttcc ttattttcct gaaggactag taacggatga agaggtggtt catcgccggc
    41641 tgcttaagcg atatgaacaa gcacctatcg gtattcctca tacaaatatg gggttattcc
    41701 atacatccag ctcattgatt tctaaaccga tcttttgtat tttcaatttg aaacatccgt
    41761 tgaccattga agggatggat agacagccag tcgatttgtc ccgtatgtta gttatgctgg
    41821 cgccttcgcc aatccaagaa aaagacggga ttcttttagg aaagatcagt ggagcaatca
    41881 tcatgaatga cttgaacacc gagatcttcc gctcaggaaa taaagaaatc gtttatcagt
    41941 tgttagcgaa aatcctgatt gaagaaataa agaaatgaag gtgaaaagat gatacagcta
    42001 ccagcagaaa aaatattgct cgatcaatcc tatcaaaatt ggaaagaagc gttgaccgag
    42061 atcggccagt ggatgaccca acaaggggga atcaaaccgg catatatcca atcaatgatc
    42121 gaaagacaag aaaaagcgag tgtctatatc gggaatttcg tagccttgcc acatgggact
    42181 gacaaagatg aagaagtagt agaagaagga atctatttag tccaagtgcc tgatggtgtg
    42241 gactttggaa caaaagagga accaaaaatc gcgacactct tatttgtagt ggctttaaaa
    42301 aaagaacatc agttagcggt gctccaagat ttagcctttt tctgttcaga catcgaccaa
    42361 gtaatggcgc tcagtgatgc ggaaaccatt gaagaagtcc aaatgatttt tgaacatgga
    42421 catatataac caatgttcac agtaaaaaaa gctgccttgc atcaagtaat aacttcaacc
    42481 aagataaaaa taagaggagc tatttttgtt gggaggttct tattactgcg gatgcaagct
    42541 tttgaaaact atttattcta gaaaaccgtt tatttgaaat aggggacggt gacaaggttt
    42601 ttgtcaccgc ccctattatt tttgtgtttt aatagctctt ttttatatag atagtgccca
    42661 tacctatgaa taataaaacg atactccata taccaagtgt caagatacca ttcatgaaag
    42721 taacctgttc tgaagctagt ggcgagaaaa tatctcctcc tatgatcaca ttttgaaaat
    42781 caacataaga agttggcaag taatgactga ttgattctat ccatccaatc gaagaaaaca
    42841 agcgatactc tgctaagaaa agacaaagaa gtgtacctaa aagattgact agagaatgtt
    42901 caaataaagc agatagaaga aaactgattg tacttaaaaa gagcacccac aacaacagga
    42961 acagaaagct ctggaaaaga tactcataca tcggcaggat tcgtatctcc tgaccaatga
    43021 tcgttcctac aggataacgg aagtctccca aaccattttt gattattact agtatagaga
    43081 cgatcaaaaa tggcatcacg agacttagca tagctgcacc ataataaatg gtaaaacgga
    43141 tgctatgttt ctttaccata ctatccagta atagattgac tagagagatt acctgctttc
    43201 ttttttcata agagatgatg gaagaaagaa acaaggcggt tatacataaa atcaaaaaac
    43261 tagaaatcat tcctgaaaaa atattttcgt agtaatttgc taaagagaga tgcgctggca
    43321 agtcaaaaat agaatatctt tggatctgat gttctttcat ataacggagc aactcgacac
    43381 gtttttgttg ttcaatgatt ggaattcctt gtctttgacc agaaatcagt cgatccagta
    43441 tatctttttc ataatgataa gttgcttcga ccatttgctg gacattccct gtgttttttg
    43501 catgtaagat tgcttcgatc agtttgttgc ttttctctaa actttccaca aattctttct
    43561 cattctcatc ttctttcaac gtttcaatca aacgttgcat ctcttcatag ttatgattca
    43621 gttcatcgaa ttctgtataa gcaagtttat gatcaaaaaa aagtgggaat gcaaagagca
    43681 cgaccaacaa tagaggaaat aaaaagttta ctttgttttt tagtaagaga ttgcgttcaa
    43741 atgtaagtaa agacatagtt acacctcata taatttacga taaatagcta aaatctcttc
    43801 catatttgag gattctgtga cgatttctcc attttttaga aaacatgctt tagaacaaat
    43861 cgattggata ttcgcgatag cgtgggaaga aagaagaatc gtcttcccct ctttctgcca
    43921 ttgtctgatg aggctattca agatatcaat acttcctggg tctaatccgt tcaacggttc
    43981 atcgaataac atgacagatg aatcactgat caagtaagca gcaagcaaga catgttgttt
    44041 cattcctaga gacatttttc caatcggcaa agtaaggtac tcagtcatct tcaatcgttg
    44101 gaaaacagtt tggcattcta ctttgctctg ccaatagtat ttgatcaaag tcaaataatc
    44161 aacagccgat agatagtcgg ataactgatt cgttgattct agaaaaaaga aagaccggcg
    44221 ataatctgta taagcagtag gagagatgtt gtgaagggac aattgatcat aagttgttgg
    44281 cagcagttgg gcaatgccat tcagcaaagt tgttttgcca aatccgttcg gggcaatcaa
    44341 agcagctact tctcctgatt ctactaaaag attcaattgt cgaatcacac gttttttacc
    44401 acgtttcatg ttcatgtttt tgatcagtaa tgtcatagat aggcctccaa tataaaattt
    44461 aataacataa tagaatggaa aacatctaaa ttaaatgcta acaaaagtta ttgtttgcat
    44521 attataaaaa aattaaaata acagttttat ttaaaattga agttttctga taccgaaatc
    44581 tttttatttt gctgacatac tcaaaccttt ggcacaaagt ttcgtgccaa agtacgacta
    44641 tttctctttt tagtaagcgg atacaattag agtatcaaaa ggagagaggg agagacaaaa
    44701 tggaacggac gattcccaaa aacaacattt cgctaaaagc gagggtacaa aaattaggca
    44761 gtactttatc aagcatggtc atgccaaata ttggagcact gattgcctgg ggtgtattaa
    44821 cggctctatt tatcccagat ggttatttac caaatgaggc tttcgctacc atggtaagcc
    44881 caatgctaac ttatctgatt cctttattga tcggttatac tggcggaaaa gtaattgctg
    44941 gtgaccgcgg atcagttgtt ggggcaattg caacgatggg tgtgattgtc ggaacagata
    45001 ttccaatgat gctaggcgcg atgatcatgg gacctcttgg tggatatgcc atcaagaaat
    45061 ttgatcagct attccaaaaa cggatcaaat ccggttttga aatgctagtc aataattttt
    45121 cagcaggtct tatcggtttt ggattagcgt tattaggttt ttctgcgatt ggtccagttg
    45181 tcgatgcatt gactcaagca atggcaaaag gtgtagagat cattttatct gcccatttga
    45241 ttccattgac aagtattttt attgaaccag caaaaatctt atttttgaat aatgcaatca
    45301 atcatgggat tttgacacca ttgggaactg aacaagtagc agaggctgga aaatctattc
    45361 tattcttgct tgaagcaaat cctggtccag gacttggcgt attacttgct tttactttgt
    45421 ttggcaaagg agcagcaaaa tcttcagcac caggagccat gatcattcac tttttaggcg
    45481 ggatccatga aatctatttt ccttacgtta tgatgaaacc gttattattc ttatcagtta
    45541 taggcggagg aatgtcagga agtttcattt tccaattgat ggatgctgga ctaagagcgc
    45601 cagcttctcc agggtcgatc attgcgattc tagcgatgac accgttcaat tcttaccttc
    45661 ctgttatttt gggcgtgatt gttgccgcag ctgtttcgtt tggtatttct gcagtaattt
    45721 tgaaagcgga tgcgaaagat acaaatgaag acttcgaaaa atctgttcaa gagacaaagg
    45781 cagctaagca agcttccaaa ggtgcccaag gtattcctca aggagctaca ttctctggcg
    45841 tacaaaaaat catttttgct tgtgatgcag gaatgggatc aagtgcgatg ggcgcttcga
    45901 tcttgagaaa aaaagtacag gaagcagact tgcctcaaac ggtgaccaat caagcaatca
    45961 gccaactgac agatgactcg aatacattga tcgttactca ggtcgaacta caagaaagag
    46021 caaaacaaaa agcaccgagc gcgcgttttg tctcagtaga aaactttttg aattcacctc
    46081 gatatgatga aatcattcaa gaattaagca gcaagcagaa aacatcagtt tctgaaattg
    46141 agaatgagcc agcagaagag tttctttcag caaacatcaa acaaatcaaa gagattctac
    46201 ttgtccacga tgatcgttcc ggatcagcaa caatggggat gaccgtgctc aaagatatat
    46261 tagacaagaa ccatttaact atcccgttaa gaaaagtcaa tatccaagat ttaaaagatg
    46321 aacctgattc actgatcgta gccaaagaaa gtttagcgga aaaagtacag atggctgcac
    46381 ctcaatccat tcatttatca gtcaacagca tggtcaatcc gcaaaaatac gaatcgattg
    46441 cacaatattt gaaacagaca gcttaaggga ggaaaacagc atgcaaagtt tgccattcga
    46501 catgatcgag ctcaatcgat cttttaaaac caaagaagaa gcgatccgct attgcggtca
    46561 gatgcttgta gaagcagggt gcgttgatga ggaatatatc gatgccatgg tagatagaga
    46621 caaaatgtta tctgtttata tggggaattt tatcgcgatt cctcatggaa cagatgaagc
    46681 aaaaaaatat gtgaaaaaat ccggcatctg tgtcgttcaa gtaccagatg gtgtagattt
    46741 tggtaccgaa gaagaagaaa agattgcgac tgttttgttc ggtattgcag gagtcggaga
    46801 tgagcatttg caacttgtac agcaaatcgc actttattgc agtgatatgg acaatgttgt
    46861 ccagctagca gacgcgctca gcaaagaaga agtaacggaa aatctagcaa ttgcttaagg
    46921 agagagaaaa atgagagcag tacattttgg tgcaggaaat atcggtcgag gatttattgg
    46981 agaggttttg gcagctaatg gatttgagat tactttcgta gatgtgaatc acacgatcat
    47041 tgatgcttta aatgaaagaa aagaatacga aatcgaatta gcagatgaat caaaagaaaa
    47101 aatcactgta aaaaatgtca aaggaatcaa caatcaaaca aatccagaaa aagtaatcca
    47161 agaaatcgct gaagcagatt tagttactac cgccattggc ccgaatatct taccttttat
    47221 tgctgagttg attgcaaaag gtatccaaga aagagaaaag gaaggaagca caacatcttt
    47281 agatatcatt gcctgtgaaa atatgattgg cggttcagca tttctagaaa aagaagtgta
    47341 taaatatctt ccggaaacat catttactga caaatatatc ggctttccaa atgcagcagt
    47401 cgatcgaatc gtcccattac aacaccatga agatccttta ttcgtccaag tggaaccttt
    47461 caaagaatgg gtcattgacg atagccaaag aaaaaataaa aaaatccaat taaaaggggt
    47521 tttatatgta gatgatctag aaccatatat cgaacgcaaa ctatttagtg tcaatactgg
    47581 tcatgcgact gtcgcttata caggtgcctt gttaggttac cagaccattg atgaagcaat
    47641 gcaagatgcg ttagttgtgg cacaattaaa atcagttttg caggaaacag gaagtttgct
    47701 gattgccaaa tgggggtttg atgcagagca gcatcatgcg tatattgaaa aaatcattca
    47761 tcgcttccaa aacaaaaata tctctgatgc gatcacacgt gtcgctcgga caccattacg
    47821 taagttaggt tatcaagaaa gatttacacg tccagtgaga gaactacaag aacataactt
    47881 gacttgccca catttgacgg caacaatggg gattattttt aattactatg atcctgaaga
    47941 tgaacaaagc cgtcaattgc atgaaatgaa gatccatgaa aacttggaac aattgattca
    48001 agaagtcaca ggaatcaatg atccgaaaac aatcgggaat atcaagcaaa acgtgaaccg
    48061 ttatgccaag caagtcgctt aaaataggat acgaaaaagg ggaatgtgac gaaatttttg
    48121 tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat
    48181 tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt
    48241 cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca
    48301 gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct
    48361 tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct
    48421 tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga
    48481 tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc
    48541 aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa
    48601 gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg
    48661 ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc
    48721 gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta
    48781 tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc
    48841 acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac
    48901 agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat
    48961 tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag
    49021 acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc
    49081 ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt
    49141 ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac
    49201 ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt
    49261 gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc
    49321 aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata
    49381 cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt
    49441 gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt
    49501 tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg
    49561 acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc
    49621 atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga
    49681 atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt
    49741 ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa
    49801 gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag
    49861 gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc
    49921 ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat
    49981 attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg
    50041 gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg
    50101 taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc
    50161 aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat
    50221 aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa
    50281 gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa
    50341 cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat
    50401 attcccattt taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt
    50461 ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag
    50521 tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc
    50581 agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt
    50641 agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac
    50701 tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact
    50761 tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc
    50821 gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt
    50881 gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata
    50941 aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc
    51001 caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa
    51061 tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca
    51121 ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat
    51181 caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa
    51241 cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca
    51301 acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg
    51361 aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg
    51421 ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa
    51481 aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc
    51541 cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt
    51601 cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg
    51661 ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca atatataata
    51721 aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg
    51781 cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct
    51841 accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag
    51901 ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag
    51961 gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa
    52021 ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa
    52081 gatattaata catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca
    52141 atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt
    52201 gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca
    52261 tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa
    52321 ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt
    52381 agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac
    52441 catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat
    52501 ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt
    52561 gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc
    52621 caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac
    52681 atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat
    52741 aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa
    52801 caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc
    52861 caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt
    52921 ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt
    52981 cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta
    53041 catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa
    53101 gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa
    53161 gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca
    53221 cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa
    53281 cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt
    53341 gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat
    53401 tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca
    53461 aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt
    53521 tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt
    53581 tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg
    53641 aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca
    53701 attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga
    53761 actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt
    53821 caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga
    53881 aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt
    53941 catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa
    54001 attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag
    54061 aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta
    54121 ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa
    54181 gataagacga acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa
    54241 agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt
    54301 aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt
    54361 tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta
    54421 cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata
    54481 ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta
    54541 tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg
    54601 atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat
    54661 atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact
    54721 ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa
    54781 aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc
    54841 gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac
    54901 atgttttttg tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac
    54961 tttttttgca atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt
    55021 gttcataaat agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt
    55081 tttttccaat cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact
    55141 aatttgttca ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc
    55201 ataaagtttt gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag
    55261 gatgagatta gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac
    55321 atttttcaga tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc
    55381 atcggcaatg atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc
    55441 gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc
    55501 ttcgcgaata atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga
    55561 atcaaaaata ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta
    55621 ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga
    55681 aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa
    55741 atattactag acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag
    55801 gaatcaagta aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc
    55861 actctttcac agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa
    55921 aagactatca tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag
    55981 caaaacatta caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg
    56041 atcaaactat ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt
    56101 tatgggatga atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa
    56161 tagatttaat actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca
    56221 agtataatac cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta
    56281 agtatggcgc aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg
    56341 aagaacaaaa taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag
    56401 gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag
    56461 acgtatttga cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag
    56521 cgcaattctt aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata
    56581 ttccggttat ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa
    56641 aatatttatt gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc
    56701 acaaaaaagc aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc
    56761 aagtgcaaat tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc
    56821 catcaatgat tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg
    56881 ttatgaagag cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt
    56941 tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta
    57001 taaagaagta gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga
    57061 tgaaatggct gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt
    57121 agaagaaaaa atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat
    57181 catggaaatc cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt
    57241 caatatgtac caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa
    57301 cgttaccgga atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata
    57361 ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc
    57421 gcaagggcgt atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt
    57481 agagatcgat attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg
    57541 cggacagcac gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat
    57601 cgttgttgct atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat
    57661 cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa
    57721 tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc
    57781 gcaaaatcgt gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt
    57841 agcagggaaa ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact
    57901 ggaagctatg caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt
    57961 ttttagagga tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac
    58021 aatggaaaaa acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc
    58081 ggttgatcga aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag
    58141 gatatgcaga tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac
    58201 cagaaacaga ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag
    58261 tgatagatat tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa
    58321 attggcatat atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg
    58381 ctcagaaaga aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg
    58441 atcagcaatt tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac
    58501 tgatggatga aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg
    58561 gattagctat ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa
    58621 agattttttt agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag
    58681 catttccaga taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc
    58741 aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa
    58801 cacttatttg acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg
    58861 acaaatagat tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat
    58921 gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg
    58981 caagaggcag ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta
    59041 tacggattgg gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa
    59101 gggagaccgc aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag
    59161 tatgtggaca actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca
    59221 ttaactttga tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta
    59281 tccacagctg catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc
    59341 ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca
    59401 gatcatgtat atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg
    59461 cgaattggtg tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt
    59521 ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct
    59581 attgatcagc atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa
    59641 cactactcac ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt
    59701 caatgggcaa aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat
    59761 caagtgcgga cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg
    59821 gctaaaggat tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg
    59881 atttttgtac aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa
    59941 aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta
    60001 gtatgataca atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta
    60061 atcgtaatag aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg
    60121 taggaaaata aaattgtagg aaaataaaaa ggagctgttg tttgtggtag attacaaaac
    60181 gtttgaccct gatctttggg ctgcgatcgc caaagaagaa gaaagacaag aacataattt
    60241 ggagctgatt gcctctgaaa actttgtctc cgaagcagtg atggctgcac aaggaagtat
    60301 cttgacaaat aaatacgcag aaggttatcc agggcatcgc tattatggtg ggtgtgaatt
    60361 tgtcgatatc gttgaaaatt tagcgattga ccgtgcaaaa gaattattcg gagcgaaatt
    60421 tgcgaacgtc cagcctcact ccggctctca agccaacacg gctgcttatc tcgctttggt
    60481 agaaccaggg gacacgatct taggaatgga tctttccgca ggcggacatc taacacatgg
    60541 atcaccagtc aacttcagtg gcaaaaccta tcactttgtt gcttacggtg ttgatccgac
    60601 aacagaagtt attgattata atgtggtacg tattttagct agaaaacatc aaccaaaatt
    60661 gatcgtagca ggtgccagtg cttacggacg aacgatcgac tttgcgaaat tcagagaaat
    60721 cgcagatgaa gtaggcgcaa aactgatggt agatatggca catatcgcag gattagtagc
    60781 agcaggactt catcctaatc cagttcctta tgcagatatc acaacgacta ccactcataa
    60841 aacattgcgt ggccctcgag gcggcatgat tttgacaaac gatgaagcat tagcaaaaaa
    60901 aataaatagt gcggtatttc ctggtattca aggcggccct ctagagcatg tgattgcggg
    60961 taaagcagta gcattcaaag aagcattaga tcctgcattt aaagaatata gtgaacaaat
    61021 catcgccaat gcaaaagcaa tggtcaaagt tttcaatcaa gcaattggaa ccagagtcat
    61081 ttcaggggcg acagataatc atctgatgtt gatcgatgtt cgcgagttag gtataaatgg
    61141 aaaagaagca gagagcattt tggacagtgt gaatatcact gtaaataaaa actcgattcc
    61201 ttttgaaaca ctaagtccat tcaaaacaag cggtattcga atcggcacgc cagcaatcac
    61261 tactcgcggg ttcaaagaag aagatgctgt aaaagtggct gaactagttg tcaaagcatt
    61321 acaagcaaaa gatgataacg ctcaactaga cgaagtcaaa acaggtgtac gcgaattaac
    61381 tgaaaaattt ccgttgcata aaaaataaaa atttaaattc cattagtaaa cagaaaagtt
    61441 caatgttggg cttttctgtt tattttttgg gaaaacggat tctttgacaa tatcggtgat
    61501 gctctctagt atatgaggtg taattttagt cttcacacta aatctcaggg aggaaaagtc
    61561 atgactgatc gtatctcgtt agaaaaggaa gcagtagcat tcagtgatgc aaatgcgcct
    61621 catccgcgta tctatgaact agcaccggaa gaaggaagag ttttactaga agaagtacaa
    61681 gaatcacctg tgaacaaata ttccgtcgat attgaagact tgatggtgga tactggcgaa
    61741 tggggaaaac tcaatattcg tctcgtacga ccagaaggga atatggataa attaccagtt
    61801 attttttata ttcatggagc aggctgggtt tttggcagtg ctcaaaccca tgataaattg
    61861 atcagagaac ttgcggttcg tacgaattcc gtcgttgtct ttccagaata tagtcgatca
    61921 ccagaagcaa aatatccaac agcaattgaa caaaattatg ctgtgttgca acagctgaat
    61981 aaattagcca agtcaaaaaa tctggatctc gagaatctaa tcgttgcagg agattcagta
    62041 ggtggtaaca tggctacagt catgacgatc ttaacaaaag aacgaaaggg cctcccaata
    62101 tccaagcaat tgctgtatta tccagtcaca aacgctgatt ttgatacaga ttcctatcat
    62161 gaattcggag aaaactattt tttgacaaga gaaggaatga tgtggttttg ggaccaatat
    62221 acgacgaatg aagaagagcg tgctgaaatc acagcttcgc ctttgagagc aaatataaat
    62281 gaactaaatg atcttccttc agcaatgatt ttaacgggag aagcggatgt attaagagat
    62341 gaaggtgagg cttatgcgcg caaacttcgt gatgcagggg ttcctgttac acaagtacgc
    62401 ttccaaggaa tcatccatga ttttgtcatg gtaaatgcta tggatcagac aaaggcaacg
    62461 cgtgcagcaa tggcattatc tacttcttgg atcaagaaaa aagaataagc tttgcttgtc
    62521 cgcaggaaaa cttcttttca aaaacggatt ttcttaggaa aaatggcgag tttgactagt
    62581 caatcacttg attttgtttt acaattaaaa agaaacgaca gaacaaagga gagcttaaaa
    62641 aatgggcaaa tttcaagtga tcgatcatcc attgattcaa cacaaactaa ctattattcg
    62701 ggacaaaaac tgcggaacaa aggtttttcg tgaagtagtc gatgaaatcg ctatgttgat
    62761 ggcatatgaa gtatcacggg atatgccatt ggaagacatc gtgatcgaaa caccgatcac
    62821 tgaaacaaca caaaaaacgt tgtctggtaa aaaagtagcg attattccaa tcttgcgcgc
    62881 aggtattgga atggttgacg gtatcttgga attgattcca gctgctaaag tgggacatat
    62941 cggtctttat cgagatgaag aaacattgga accacatgaa tatttcgtca aacttccaga
    63001 agacattgat gcacgtcagt tgtttgtagt agatccaatg ttggcaacag gcggatcagc
    63061 aatcatggca atcgatgcat tgaaagaacg tggcgcgtcg aacattaaat ttgtttgttt
    63121 ggtagcagca cctgagggag taaaagcttt gcaagaagcg catcctgata ttgacatcta
    63181 tacagcttct ctagatgaaa aattgaatga acatggttat atcgttcctg gactagggga
    63241 tgcgggtgac cgtttgtttg gtacaaaata agtaaatacg aaaaagggtg tgacacaact
    63301 tttgtcacat ccttttttgg tcatttttaa cgtttgatgc agaacagctt tttcacagct
    63361 ttcgtttgca tataaaaaaa ccatcccaaa aatgcagaga tggtcaaatt caaatctttt
    63421 ttagttcttt gtagttaacg attactacac ccttactttg cgtcatcaag ttcgcatttt
    63481 ctgcagtttc atcaatctca acaacagcgg aatttttcaa ttgctttgaa atcgttccag
    63541 tttgcgactt gccgtgaatt gtgaacatta cgtgagtatt gatcttgaat ttttcaccaa
    63601 tttccgatgg tacgatagtt gtatcaaatt ttccaaaagt tgccattttc ataaaacctg
    63661 tctttcacat caattatacc acgttttatg aaaaatatca tgaaattaaa ctaattttcc
    63721 atcggactct ttacaatcag ccaaatagag tatataattt cttttggata aggccagctt
    63781 agctcagttg gtagagcaac gcactcgtaa cgcgtaggtc gtaggttcga tccctatagc
    63841 tggcattaaa agagaagaca gatatatcaa ggatttttaa tccattgata catctgtctt
    63901 tttgtttaaa ggaaataaag tatgctttct tagcaataga gcatgtatta tttctataaa
    63961 aatttaggag aataaaacga ctagcaatat agctgtgaaa tcaaatatca catgaactgc
    64021 ccaacttgta atgatcgagt tgcttttaat ggcagcttgg ttgaataaca atcttgccac
    64081 cccttgtatc aaaaggatgt gtgctacagt gtgtaaaata tttccattat cataagtact
    64141 gtaatggata aatccaaaga tgattgctga caagaaacta gcgacaggaa tgctgaactt
    64201 actagaaaaa atagcgagaa aatacactga gaacaattct tctccaagta tcatgatagg
    64261 caaaataata aataataacg ggctgaaagc ctcatttatt ggattgcctg ttaaacccca
    64321 tttcaaaatt tgttgcaaaa ataccgagac tgcggcactg attactacat tgataaaaaa
    64381 atatttggct atatttttga caggagcgac aggtttcgag aacatttttt tcgtatcttt
    64441 tttaccaaaa acaagtgtaa atgctataaa tccagtgata gttaaagaaa aaatgctaat
    64501 aatggatggc gcaaatagca accctaacaa accgagtaca acgacaatag tgcccaatat
    64561 ccctttttta agttctattt tttttcctaa aatgttattc atgataataa ctcctactat
    64621 tcagtttttg aagatagagt cagtatacat gaagagttaa aataggcaat gtttttttat
    64681 ggatatttgt attgctaaaa atttatctta tatattcatt ttgattatac tacttttatt
    64741 tgtaaaaatt ttctagcaaa accaagtgct tgcaactgat taagcgtaca attttttaga
    64801 tgttccgagc gtacttcaat catttcaaag gagttgctac ttaaatcgat attttttaaa
    64861 tcagtatcaa aaaagctagc attttctaaa tcattagtag aaaacattat tttagtgagg
    64921 gaacagtcta caaaatctgc gcttgataag acagagtgct caaaggtact ttcttttatg
    64981 tttgaaccag ataaatttac atagtccatt ttacaattct cgaataacgt gttcccaata
    65041 taactttcca tcaatttagt acctgttaat ttacaattga caaatttcac gcgatgcaac
    65101 atgctttttg tcaatataca gcctgaaaaa tcacagtttt cgaatataca gtcggtaatc
    65161 tccattcttt gaaaatcatt ggaagcaaaa aatgcatact tgaaaataga tttgtaaata
    65221 attggatggc agattatttg gttttcgatg acctcttttt gtgaaaggat attatacagt
    65281 tcaaaatctt cgttttcata gatatgaaaa aaggatcctt tattcaagct tgcttcatta
    65341 actttaggaa aaatcatatt taattacctc cattttcata aagtcatatt aacaaaagct
    65401 aaaccaactt acattagcag aaaatgagat aggttttcgc ctttttcgat aacgatagtg
    65461 tcgctatctc ttgaaacgtt cttagaattg ccctgagaga cacaaattag gcgtaattct
    65521 aataaaaatc ttagaataaa aatttttact gatttaattt agaatgtttt taaaataaaa
    65581 atcgttgcca taacagtgta ttgaaaggtt ttaacaatcc agtaatgatt taaaaaaatc
    65641 tagatgtagc gtatactttg tttatagaat gtagtgggaa gaaatatatt tttgggagga
    65701 aatcgtgatg tctaaaagtg aagaaataga aaacatggta ctaaaattat atgatctcgt
    65761 tttaaatcca gagatcaaag aaaaggaacg tatacttttg atagacgcaa agacaggctt
    65821 agaaaaaggt cagtattatc ctaaagtcat aaataatttg gaacgtagtt tacgtccgtt
    65881 agcaatcagg ggagaattgt ctaaaccagt atcaccgttt tatatggaga tatcaacaat
    65941 aggaaaattt gaaaaagaat taggtcgagg aatggcttcg gcaccgatta cttttgggca
    66001 tttataaaaa cgagttattc atctcaatga attaaaaagt atagtcaatc tcataatgca
    66061 ggctaggttc atttatttga acagagtctg tattttttta ttctaaataa agaaacagat
    66121 gtttctttat attgtatttt atcctttaat taacacaaaa acagctagta taaactaata
    66181 atgttaatta aaagtgtatt ttatgaaact atcgttattt attaatgttg catttttgta
    66241 agttaaaaat tggaaatata gattgaaaaa atgaaagcaa taagtaaaat aaaatgaata
    66301 tatgcgaaaa aataatttac attaggaaaa accttgtaaa aacagttttt tggcatattt
    66361 attttttata aatatttgta aaataactat caatttttta gttaaaagat tggaaatgag
    66421 tgggggagga attgaagaaa ggatttttga gagatgatat agtaggtttt atttttagtt
    66481 aaaatagggg agatagaaaa aatgaaaaag tgtagaaata ttattttatc aatgttattt
    66541 attattacta atataacatc actgattcct gttcatgtct atgcggatgc aggcagagat
    66601 atcagcagta atgtcacttc gttgaccgtg gacccaacga atattacaga tggaggaaac
    66661 ataaaagtaa aattctcgtt tgacgaaaaa aaacaaaata tccaaccagg tgattatctt
    66721 tggatcaatt ggccaagtga aggaaatatt cgcggtgaag gattccaaaa agaaatccca
    66781 ttaatgattg aaaataaaaa tgttggaact ttaacggtca gaaaagattc tgcgcaggtt
    66841 gtgtttaatg aaaatattaa aaacctagac tcagtagaag gttgggggca atttgagata
    66901 caggccagaa acgtaaccga taccggtgaa gaaaatacgg gaccattcac cgtgacgagc
    66961 ggtgataaaa cagctactgt aaatgtgaca aagccagctt ctggttcttc ttctagcgtt
    67021 ttttattata aaacaggaga catgctacct gaagatacta agcacattcg atggtttttg
    67081 aatattaaca ataacggcac ttatgttgaa caaccagtta aaatcagtga tgaaatccaa
    67141 agtggacaaa gattagatcc aagtacgttt gaaattaatc aaatacactt aggtgaacag
    67201 aaggtttata gaggagaaga gggaatccaa caatttttac aagatttccc cagcgctaca
    67261 tttaattttt cagtaactga taattacatt gaaataacta taccaaaaaa ctttgtcaat
    67321 cttaggaaaa taatggtgag ttataagacg atcatagaaa acccagaaca aataaatttt
    67381 gagaatcatt cggaagcttg gtttaaagaa tttaataaac ctgctgttga tggagaaagt
    67441 ttcaatcata cagttaaaaa tatttcagct tctggtggag tcaacggtac agttagaggc
    67501 gaattgaaga ttttcaaata tatcaatgac acagagattg gtatcccaaa tgtgactttc
    67561 gaattaagac gagcagatga acagcctatt caaggacagt ctagtatcct gttgacttcg
    67621 aatgaacagg gagaagctag tatcaaaggc ctgcaagtag gagactatgt tgtaaaagaa
    67681 aaagaagcac ccaattggat tgattttgat ccactaagtt caaatgaact caaattctcc
    67741 ataaacgaaa atgatacaga gggagtcagt ttacctattt ataacaagaa aaaggttacg
    67801 aacatcacag caactaaaat ttggaacggt ggaaccactc caagaccgag tatttatttt
    67861 aaattattca gagcaagtac aaacaattgg gaaccagttc ctgatgcaga aacaaaacga
    67921 ttagacaatg gaataacttc agtgacttgg gaagatatcc aacagtatga tgatagtgga
    67981 aacgaatata cgtttaaagt gcaagaagta gatcaaaacg gaaatgatta tgtcccttca
    68041 ggttatcaaa aaattgaaaa cgggctagtc gttacaaatg agaataaaga agtcatttca
    68101 gtctcaggac aaaaaacatg ggaagacaat gagaaccaag acggcaaacg accgacgacg
    68161 atcacagtaa atctattagc cgacggtcaa ccgatccaac acaaagaagt aagtgaaaaa
    68221 gatgattggc gctatcgttt cacaaatctg ccaaaataca gagacgggca agaaatcatc
    68281 tatactgtaa cggaagacaa cgtgcccgaa tacagtacga cgattgacgg gtataacatc
    68341 aaaaacagtt atacaccgga aaaaacaaat atatctatac caggtagcca tataacaccg
    68401 tggaaaaatt ttccagagaa gacagagaga gagaaaatta gaaatctatt ctctcaaaaa
    68461 ttgcaaatat ttgctcatac aggagaatcc agcgaacaaa gaagcaatta tattagtaag
    68521 agagctgtac ctaaacagat aacaaataaa tcaaaaagca ttcttcctaa aacaagtagt
    68581 aaaaaatcta gttttgctgt aatcattggt ttattgatag taactatctg tgctgggata
    68641 ttcttacaaa aatataaaaa agtttagtta gaatataata ttttttgtta aatatgactg
    68701 aaatcaaaag aataaaattc cgatttataa tcgaaaaaag aagcattttt atatatgctt
    68761 cttttttcgt agaatcaata aatatggatt tggctaacta tggaagaata ctcgtattag
    68821 ttttcagcgt tcatactagt tgttacattg tttgattggc caaaagaatt tctgatatat
    68881 tttgtgctaa ataaagaaaa agacgcttga attgggaaat aagaaaacta ctctatcatt
    68941 acaaattttc ataaactggc agatgttcta agtaaacaag tatcttttca aagtcggaaa
    69001 aatccataat caacgtagtg gtattgatat ttggatgaaa gcctacggta tcttgacgat
    69061 caatagcagc atcgatcacg acttggattt ttttctcttt gtcgtgcatc aatgctaatg
    69121 gagtcactgt acctgctgga acgcctagga ggtcaggaag ctgttcttca gaaacaaaag
    69181 ataagcgctt ttcttttaat tgttcagcta gttgttttaa atcggcgtgc ttttcatcag
    69241 gcaagatgac aagatagatt tgttttcctt ttcttgattt caataataga ttttttactt
    69301 gcggaccagg tagggaaaaa gggacatttt tgactgacgt aatcgcagga tgatcgactt
    69361 tttgaaaaga gatacccagt ttttttagta gttcataagc ttcttgttcg gttgcacgac
    69421 tcatcgcgca tcaccctcct ttttttatta gtgtatcata aaaaagagtt gacaaatgaa
    69481 aaataatcat gtaaattaca cgtaaagtta aaacaaatga catcgaaaag aagagtagcc
    69541 gttaggtgtt tttagagagt ctctggttgg tggaaagagg cagcagttaa ccgtgaaaca
    69601 catcttggag tcgattttct gaagcgtata gtaggaaaat ccggggagcc cgttacagct
    69661 gcggtcgttg ctagatgacc agataaggct ggcttttccg tgaggagtcg gtaaaaaaag
    69721 gtggaaccac gtgattaacg tcctttgatc ttcggatcaa aggacttttt gttttcatct
    69781 gaacggcaac gactgtgtga ggttttttct gcaaggaaaa aataaacaga ggtggaacca
    69841 cgtataatac gtcctcttgg catttgccaa gaggattttt ttattttaaa ggaggaaaag
    69901 aagatggagt atttgattga agttatgccg caattattag taggagcact cacaacattg
    69961 aaattatttt tatttacctt gattggctca ttaccattag ggattgtttt agcattagga
    70021 ttgtctttgc attttaagcc gctacgctac ttgcttcaaa catatgtatg ggttatgcgg
    70081 ggaacaccgc tgttgttgca actgattttt attttttatg ggttgccgac gattgggatc
    70141 gtttttgatc gtttcgaagc agcactcatt gcctttatct taaactatgc agcttatttt
    70201 gcagagatct ttcgtggagg gatacaatcg attcctcaag gtcaatatga agcagcgcaa
    70261 gttttgcaat taagtccctt tcaaacggtg acgaaaatcg tcatcccaca agtgacaaag
    70321 attgttttac cttctgtagg gaatgaagtt atcaacttgg tcaaagattc ttccttgatc
    70381 tatatattag gtttaggtga cgtaatgcgt gctgggaaaa tcgcgatgga acgcgacgcg
    70441 actttactgc ctttgctagg cgtggcaatc atctatctta cattgactgg tattctaaca
    70501 atcgtaatga aacaagttga aggaaaatta aattattacc gctaactgat aggaggaaga
    70561 aatatgattg aattgaagaa agtgaacaaa gcatttggtg aaaaaaaaat aatcaaagat
    70621 ttgaatctaa tcattccaga tgggaaaaca ttagctatcg taggtccttc cggtggcggt
    70681 aaaaccacgc ttttacgtat cttggctggc ttagaaagtt ctgacagcgg agaattttat
    70741 ttagacggtg taccgttcaa cccattcgag cttaaaatga aagaacaagt tgtaggagtc
    70801 gtattccaag acttccagct atttccacat ctgaatattt ttgaaaacat taccttagca
    70861 ccaaaaatgg tattgaaaca gacaaaagaa gaatacacca aaaaagcaga agaattagcg
    70921 gcttcattag ggattagtga tttattgaat atctatcctt atcagctttc tggcggacaa
    70981 aaacagcggg tagcgattgc cagagcattg gctatgaatc cacgggtatt ggcttatgat
    71041 gaaccaacaa gtgctttaga tcctgaatta cgccagcaag tcgagcgttt gatcctatca
    71101 ttgaaagaag atggggtaac ccaaattatt gtcacccatg atttagtatt tgcagaaaat
    71161 gtcggtgatc aattactaaa agtttcccca attcattaag aaaggagaag atagagatga
    71221 aaaaaaccag ttttctattc gctttgatcg caggtcttct tctttttgca ggctgttcga
    71281 acaaaaaaac ttcagcagat aattgggcga ctatcaacga agagaaaaaa atcgttatag
    71341 gtttagacga tacatttgtt cctatgggat ttagagataa agacgggaag ctcacaggat
    71401 ttgatattga tttagccaaa gcagtctttg aacaatatgg gattacggta gactttcagc
    71461 ccattgactg gtcaatgaag gaatttgaac tgaacaatgg aacgatcgat ttgatatgga
    71521 acggctattc caaaacgccg gcaagagaaa agaaagtgca atttacaaaa ccttatatgg
    71581 aaaacgatca agtgctgatc acacctaaag aatcaggaat cacaaacttt ggacaaatga
    71641 ataataagag attaggtgcg caaaatgggt catctggtta tgatgtattt acgaaacaac
    71701 cagaagtatt aaaagagata gtcaaaaacc aagatgctgt tttgtatgat agttttaatg
    71761 aagcattgat cgatctgaaa agcagacggg tcgatggtct gctgatggat aaagtatacg
    71821 cagactatta tttgaaacaa agaaacgaac tagaagactt caacataaca aaaggttctt
    71881 atgagagtga ggattttgca gttggtgcac gcaagtcaga tagtacatta gtgaaaaaaa
    71941 tcaatgaagc cctagatcaa ctagagaaaa caggtgaatt ccaaaaaata tccgataaat
    72001 ggtttggcga agatgttacg ccgagaaatt aacaaatagg ggactgtgac aaaagacgtg
    72061 tcacagtccc tttttccgaa taaacagtgt tctcctgcca actccttgtg actcggagct
    72121 gaatggcagg ctcacaacct cttggtaaac ggtgttcaaa agccagtttt tcggtattaa
    72181 gccaaattta tgcaaaaatg tagaaagcca ttttcacaaa atttttctta ctactcgaaa
    72241 ctaagcgact ttttcacaac ctcctttaca taattttatt ttgttgtgga aggggtttcg
    72301 tgttattcta aaagaggaac gattgaaggt tataggaaag gaagagatga atggaacaca
    72361 aagaacttac ctcatttcca aaagattttc tgtggggctc tgcttctgca gcgtatcaag
    72421 tagaaggagc ttggcaagaa gatgggaaag gagaatcagt ctgggatcga tttgtacgga
    72481 tacctggaaa gacatttaaa ggaacgaacg gtgatttggc agtagaccac tatcatcgtt
    72541 ataaagaaga tattgcttta atgaaagaac aaggtctgaa agcttaccgc ttctctgtag
    72601 cttggacacg gatttttcct aatggacgag gagaagtcaa tcaagctggg ctcgcttttt
    72661 atgagagatt gatcgacgaa ttgattgaaa acgatattga acctatgttg actttatatc
    72721 attgggatct tccacaagca ttgcaagatg aatataatgg ttgggaatca cgtcagatca
    72781 ttgaagattt cactcattat gcagaaacat tatttgaggc attccgcggg aaagtccatt
    72841 actggattag tttgaatgaa caaaatatct tcacttcatt aggttatttg ttagcagcac
    72901 atccgccagg tgtgacagac ccgaaacgaa tgtatgaagt taaccatatt gctaatttag
    72961 caaatgcatc tgtcatcaat aaatttcacg agttagaaat gcctggaaaa atcggaccaa
    73021 gctttgcgta tacgccaaat tatccaattg acagtaatcc tgaaaatgtt ctggctgctg
    73081 aaaatgcaga agacctgatg gccaattatt ggatggatgt ctatatgtgg ggaaaatatc
    73141 cgattgctgc catgaggttc ttagaagaaa aaggatgggc accaacgatt gaagctggcg
    73201 atgcagaatt gctagaatct gctaaaccag attttcttgg gatcaattac tatcaaacgg
    73261 cgacgaatgc attcaatcca ttaaacggag ttggtgctgg aaaaatgaat acgacaggaa
    73321 aaaaaggttc atcagaagaa actggagttc ctggaatgta taaaaaagtt gagaatccat
    73381 ttgtcgaacg aacaaattgg gactgggaga ttgacccaga aggattaagg atcggactgc
    73441 gtcgtatcac aagccgttac cgcatgccgg tactgattac ggaaaatggc ttaggagagt
    73501 atgacaagtt gacagaagat aaacaaatcc atgacgacta tcgaatcaat tacttacaaa
    73561 gccacgtcaa agccatcaaa gaagcaattt cggatggagc agaagtccta ggctattgca
    73621 cctggtctta tacagatttg cttagctggc tgaacggtta tcaaaagcga tatggatttg
    73681 tatatgttga tcaagacgaa acacaagaag gatctttgga acgatataag aaagacagtt
    73741 attactggta ccaaaaactg attgaagaaa atggagagaa cctttagttc acatacttaa
    73801 aacaagaagg tacggctgga tatggccgtg ccttttcttg ataaaatcat ttagaaatta
    73861 agaaaaactg taaaataagc tgaaaaatga aagaaagcgt cagttctttc aaacaaaact
    73921 ttagttccct tacttttttt tgtataatga aacttgatga aatgagggat aataaatggc
    73981 acaaaagaaa cggcctacta aaaaaaggaa aaagacgaaa aaaacgaaaa agcaaaaaca
    74041 gcagcaggaa caaatgctga cgattggtgt tgggtttgcc ttgattttat ttgctgtctt
    74101 cggcttttta aaattaggtt ttttaggaat attgattgca aacggctttc ggatcattgc
    74161 aggaaatact taccaaatcc tctgtctttt attagccgta ttaggatttt ggattgtcat
    74221 taagaataca gagttttcaa ttggtaaaaa ccgacgctgg tttggcggca tactctttta
    74281 tttcggtatc ttattattgt tacatgccca tttatttggc aaactccata ctggggaacc
    74341 aaatatcatg gggacgacat gggatttgtt agccagtgat ataaaacaaa gtcaagtaga
    74401 caataacgtt ggtggtggga tgattggagc aatcctttat cattttactt acttcttgat
    74461 tgcacagcct ggaagttatt tagcagcagt gctattactg gcaggaggag cattcctgtt
    74521 cagtaatctg gaaggctatc agctgttaaa tggtatccaa tcaattggag aacgagtaca
    74581 ggaattattg gaaggtgatc ctgccaagca agctcgaaag caagcggcaa aggaagagag
    74641 aatgaaacag cgcgcagaag cgaaagaagc aaggcgctta gctgcaaaag aagctgcaga
    74701 aaaagaagct gcagaatatg agaagaaaaa agcggtgagc cagcaaaggg aaaatactgc
    74761 tgatgaatgg caggaaccag aaaatacaga gccggagcag ctaagttttg ttccaatcga
    74821 cagttttcaa gaaaatatcc atcctgcgaa tctagagaaa ccagtaccag atacaccaaa
    74881 acagaccaat acagcagaag gtttttcaga tgagttgcca gaggatgacg gtacctcatt
    74941 agaatttgag attgaagcag aacaggaaaa tcaagactat gaattaccga cagttgattt
    75001 gcttgattct ataccaactg tggatcaaag tgatgagtat aaaaaaattg aaaaaaatat
    75061 cggcgtatta gaacaaactt tccaaagttt cggtgtcgat gccaaggtcg tcaaagccag
    75121 cttaggacca tccgtcacaa aattcgaagt ccagccggct gtaggggtaa aagtaagtaa
    75181 aattgtgaac ttaacagatg atatcgcgct tgctttagcg gcgaaagatg tccggatgga
    75241 agcaccgatt ccaggtaaat cactgattgg tattgaagta ccaaatggaa agatcagtat
    75301 ggtttccttt agagaaatca tcgaagcaca accaaaccac ccagataaat tactagaagt
    75361 acctttagga cgtgatgttt ctggacgggt acaaacggct gatctttcga agatgcctca
    75421 cttactcgtg gctggttcga ctggtagtgg gaagtcagta gcaattaatg ggattatcac
    75481 aagtatatta atgcgtgcta agccccatga agtaaaactg atgatgatcg atccgaaaat
    75541 ggttgaattg aatatgtaca acggcatacc tcatctgttg acgccggtcg tgacgaaccc
    75601 tagaaaagca gcgcaagcct tacaaaaagt agtacaagaa atggaagaac gatatgaaaa
    75661 attcgcggca accggagtaa gaaatatttc tggttacaat gaatttgttc aacagaaaaa
    75721 cttggaaaac ggaacgaaac atccaacctt accattcatc gtagtgatcg tagatgaatt
    75781 agctgatttg atgatggtag ccagcaatga agttgaagat gcgattattc gtttagcgca
    75841 aatggctcgg gcagcgggga ttcatatgat cctagctact caacgtccaa gtgtggatgt
    75901 tatcacagga atcatcaaag caaatgtacc ttccagaatg gcatttgcgg tatcaagcgg
    75961 tacagattct cggacgatca ttgattctaa tggggcagaa aagctcttag ggcgaggaga
    76021 tatgctattc ttgccaatgg gtgagaataa accgatccgt gtgcaaggag cattcatttc
    76081 tgaccacgaa gtagaacggg tcgttcaatt tgttacagat cagcaagaag ctcattatga
    76141 agagaaaatg atgccgacag atgaagttga aacgacaggt gctccagaac agccacaaga
    76201 tgagctgttt gaagaagcaa aagcacttgt cgttgaaatg caaacggcaa gtatttccct
    76261 tctccaaaga agatttcgga tcggttacaa ccgagcagca cgtttagtag atgaactgga
    76321 agctcatgga gttgttggcc cgtcagaagg aagcaagcct cggaaagtat tcattgagca
    76381 ggaagaaaca tcagaaacgt tgccggacga taatgacatg taaaacttgt gtgatgaagg
    76441 gttgaaaaac gaataaccaa taaaaagaca aggcatgatg ataccaaaag aaaaaatggt
    76501 ttttttccat cttttctaat acggtatgat gtcttgtctt tttagttttt gtgagattaa
    76561 agttctattc gatttatttg tgaagtattg cattaaggaa atgaatcatg tatagtatgt
    76621 agcgaaactt tgagaaaaag agggaaaata ctttggaaaa acagtccatt tatggcttga
    76681 cgaatgaaga attaatcaat tggtttatag aaaacggcga gaaaaaattc cgagctgccc
    76741 aagtttggga atggttgtat caaaaacgtg taagtaattt cacagaaatg acgaatctat
    76801 cgaaacaatt gatcgaaaaa ttatcggagc attttatcat caatcctcta aaacagatgg
    76861 tcgtccaaga agcttcggat ggtacagtaa aatatttgtt tgaactccct gataaaaaca
    76921 tgattgagac tgtactgatg agacaagaat atggcttgtc agtttgtgtg acgacacaag
    76981 taggatgtaa tatcggctgt acgttttgtg caagcgggct gctcaaaaag aaccgtgatc
    77041 tgactgctgg agaaattgtt gcacagatca tgatggtcca acattatttt gatgagcgca
    77101 atcttggcga acgcgtttca catgtcgttg taatggggat cggtgagcca tttgataatt
    77161 acgacaatgt aatggacttt ttgcatatca tcaatgatgc caaaggattg gcaattggtg
    77221 ctcggcacat tacagtttcc actagtggat tagcacacaa aatcaaggaa ttcgctaata
    77281 acggcttgca agtcaatctg gctatttcct tgcacgcgcc gaataatgag gtgcgaacat
    77341 cgatcatgcg gatcaaccga agtttcccaa ttgagaaatt gatggaagct gtggatgagt
    77401 atttagagaa aacaaaccgt cgaatcacgt ttgaatatat catgttgaat caagtaaatg
    77461 atagaccaga gcatgcgcaa caattagcag atctattaaa agataagaaa aaattagcat
    77521 atgtcaactt gattccatat aatccagtca gtgaacatga tcaatattct cgcagtccaa
    77581 aagctgatgt attgagattt tatgatgtat tgaagaaaaa cggcgtaaac tgtgtgatac
    77641 gtaaagaaca tggtacagat attgatgcag cttgcggaca attgcgaagc aagcaaatga
    77701 aaaaaacagt tgccaaataa tcgtatccta ctcgtttttt caattaccat aaaaggagca
    77761 gttttcttaa ttaaggaact gttcaactta aataagagaa aagattctat agcgaaagct
    77821 ataaagcttt ttttgacaag aaaaaccctc atcaagcaaa gaaatgtcct caatttgatg
    77881 acagcctgct tgatgggggt tttagcaatt atttaactga ttttcttata tccttgctgg
    77941 ctttcttgtg tagcatgata agtttctacg tcaagaatgg cctgtttaaa tttttctcgg
    78001 gtgatttcat aaggcacatg tttaatatca tttgttgcca tggctttatc taagattgct
    78061 tctaaatcgg tcgtgacatt gagattcatg tcggttaacg atactggaag ttggttcttt
    78121 ttcataaaca catagatttt atcaaacaaa tcgaactgct gatccatcat caataaggtc
    78181 agtacaccat aactgacaga tgctccgtga aggtatccct ccattttttc tagaacagtc
    78241 gtaccgtaat agaatgagtg tgccatagca gaattatagt tattgttaac taaaacagaa
    78301 accaatccgg tagtaacaat gatatccgaa acgacttgtt caattgcata tgagggacga
    78361 tcgtcggcac tatctttcaa tgcttgcgta ccataagtca agagacgatc aatgcacatt
    78421 tttccgattt ggattcctaa tctatccgtg tagcctagat catcgccacg agcagaaaaa
    78481 gtagattcga cttctttgga taaagcatcg ccaatacctg cccataagta tttatcaggt
    78541 gcttcggcaa taattgctgt atcaatgaag gtgtgtacag gtggttttga aggaaagaag
    78601 agtccgtcca ttacgccttc ttcgttatag atgacacata ccgcagtgac gggcgaacag
    78661 ttcgaaccaa tagtgggaaa ggtgaagact ggtttagcta gtttttcacc aatgactttt
    78721 acagtatcgc aagcacggcc accaccgact gcaaacagga cgtctgcttt ttggacactt
    78781 tcatgctgga tcaactgttc aatatttcca taagttgaat tacccccgta ccagagactg
    78841 gcgacaacct ctatttcctg tgtcaaagct acttttattt tgttttctgc ctttgaaagt
    78901 gcagtcttcc ctccaatcag cactactttt gtcccatatt ctttgacgat tccatttgct
    78961 ttttcatacg catctgttcc aatggtataa tttggtaaga aaacactttg actcatattc
    79021 atttccttct ttcttcgttg aaacgggtta aaattttaaa gagtgatcga tctgactgcg
    79081 gctgtagatg gagtagaggt gaacctaaga caggataagt gatgaataag gtggcatgaa
    79141 caccttgaaa tcatcaataa gtatcctaaa aacgaacaag tacaaaaaca ttgaaaacga
    79201 caataatgaa tttttgttcc tcttagtatt tctaccgatt ccctttgctt ttttgtaatt
    79261 atctaaaaat tctaaaaatt aagattatta tatgaaaaca ggttttattt gtcaattcat
    79321 aattggtttt ttttaaagca aaagataatc tatatcatga tgaacaaaca gagttttttc
    79381 ctccaattga tggctttcct gatctttcct attttgaata aagtgtttct gtataatttt
    79441 ttattttata agtaagataa ataatgaaag aatagagata ctgattggta gctaaagatt
    79501 tttgagcgag aacatttcgt tttttcaaaa ggactgttag aataagcaag aacaaggggg
    79561 aagacgtatg ataatcagtg aatttgaccg taataatcca gtattgaaag atcagctttc
    79621 tgatttactg agactgactt ggccggaaga atatggagac agctcggcag aagaagtaga
    79681 agaaatgatg aatccagaac gaatcgcggt agcagcggta gaccaagatg agttagtagg
    79741 atttattggt gcaatccctc aatacggtat cacaggttgg gaattgcatc cattagttgt
    79801 agaaagctcc cgacgaaaga accaaatagg tactcgatta gtcaattact tagaaaaaga
    79861 agtagcttcc agaggaggaa tcacgattta tttaggtacg gatgatttag accatggaac
    79921 aacgttaagt caaacggacc tgtatgagca tacatttgat aaagtggctt ccatccagaa
    79981 ccttcgtgaa catccgtatg aattctatga aaaattaggt tataaaatcg taggtgtctt
    80041 accaaatgca aatggctggg acaaaccgga tatttggatg gcaaaaacga ttattcctcg
    80101 accaaattct caataataaa aagaggttgt gacagaagta atcagcttca agaaataaga
    80161 aggaatttac gaaaattact tcttgaattt ttgtgaaatt ccaacttatt tccgaagaag
    80221 ctacttttgg aacaccgtgt accagaggtt gtgaaaaagt cgcttagttt cgagtagtaa
    80281 gaaaaatttt gtgaaaatgg ctttctacat ttttgcataa atttggctta ataccga
//
LOCUS       DAIGSZ010000005        61795 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.005, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000005 DAIGSZ010000000
VERSION     DAIGSZ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.005"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(294..1142)
                     /locus_tag="NOB31_000344"
     CDS             complement(294..1142)
                     /locus_tag="NOB31_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0972588.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1366..3306)
                     /gene="thrS"
                     /locus_tag="NOB31_000345"
     CDS             complement(1366..3306)
                     /gene="thrS"
                     /locus_tag="NOB31_000345"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HCI0972589.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3643..3822)
                     /locus_tag="NOB31_000346"
     CDS             complement(3643..3822)
                     /locus_tag="NOB31_000346"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HCI0972590.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3869..5692)
                     /gene="cadA"
                     /locus_tag="NOB31_000347"
     CDS             complement(3869..5692)
                     /gene="cadA"
                     /locus_tag="NOB31_000347"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCI0972591.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5970..8249
                     /locus_tag="NOB31_000348"
     CDS             5970..8249
                     /locus_tag="NOB31_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0972592.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8342..8989)
                     /locus_tag="NOB31_000349"
     CDS             complement(8342..8989)
                     /locus_tag="NOB31_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972593.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(9168..9887)
                     /locus_tag="NOB31_000350"
     CDS             complement(9168..9887)
                     /locus_tag="NOB31_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0972594.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(10018..11169)
                     /locus_tag="NOB31_000351"
     CDS             complement(10018..11169)
                     /locus_tag="NOB31_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HCI0972595.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11386..12126)
                     /locus_tag="NOB31_000352"
     CDS             complement(11386..12126)
                     /locus_tag="NOB31_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0972596.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(12130..12453)
                     /gene="rsfS"
                     /locus_tag="NOB31_000353"
     CDS             complement(12130..12453)
                     /gene="rsfS"
                     /locus_tag="NOB31_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HCI0972597.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12510..13103)
                     /gene="yqeK"
                     /locus_tag="NOB31_000354"
     CDS             complement(12510..13103)
                     /gene="yqeK"
                     /locus_tag="NOB31_000354"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HCI0972598.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(13087..13737)
                     /locus_tag="NOB31_000355"
     CDS             complement(13087..13737)
                     /locus_tag="NOB31_000355"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HCI0972599.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13747..14058)
                     /gene="yhbY"
                     /locus_tag="NOB31_000356"
     CDS             complement(13747..14058)
                     /gene="yhbY"
                     /locus_tag="NOB31_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HCI0972600.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(14074..15183)
                     /gene="yqeH"
                     /locus_tag="NOB31_000357"
     CDS             complement(14074..15183)
                     /gene="yqeH"
                     /locus_tag="NOB31_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HCI0972601.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(15180..15707)
                     /locus_tag="NOB31_000358"
     CDS             complement(15180..15707)
                     /locus_tag="NOB31_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HCI0972602.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15887..16672)
                     /locus_tag="NOB31_000359"
     CDS             complement(15887..16672)
                     /locus_tag="NOB31_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HCI0972603.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16665..17534)
                     /locus_tag="NOB31_000360"
     CDS             complement(16665..17534)
                     /locus_tag="NOB31_000360"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HCI0972604.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17535..18914)
                     /locus_tag="NOB31_000361"
     CDS             complement(17535..18914)
                     /locus_tag="NOB31_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HCI0972605.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18922..19341)
                     /gene="fabZ"
                     /locus_tag="NOB31_000362"
     CDS             complement(18922..19341)
                     /gene="fabZ"
                     /locus_tag="NOB31_000362"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCI0972606.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19366..19842)
                     /gene="accB"
                     /locus_tag="NOB31_000363"
     CDS             complement(19366..19842)
                     /gene="accB"
                     /locus_tag="NOB31_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HCI0972607.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19845..21080)
                     /gene="fabF"
                     /locus_tag="NOB31_000364"
     CDS             complement(19845..21080)
                     /gene="fabF"
                     /locus_tag="NOB31_000364"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HCI0972608.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(21099..21836)
                     /gene="fabG"
                     /locus_tag="NOB31_000365"
     CDS             complement(21099..21836)
                     /gene="fabG"
                     /locus_tag="NOB31_000365"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HCI0972609.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21848..22765)
                     /gene="fabD"
                     /locus_tag="NOB31_000366"
     CDS             complement(21848..22765)
                     /gene="fabD"
                     /locus_tag="NOB31_000366"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCI0972610.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22872..23096)
                     /locus_tag="NOB31_000367"
     CDS             complement(22872..23096)
                     /locus_tag="NOB31_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCI0972611.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(23149..24111)
                     /locus_tag="NOB31_000368"
     CDS             complement(23149..24111)
                     /locus_tag="NOB31_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HCI0972612.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(24121..24561)
                     /locus_tag="NOB31_000369"
     CDS             complement(24121..24561)
                     /locus_tag="NOB31_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0972613.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24867..25832
                     /locus_tag="NOB31_000370"
     CDS             24867..25832
                     /locus_tag="NOB31_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCI0972614.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25889..26119)
                     /locus_tag="NOB31_000371"
     CDS             complement(25889..26119)
                     /locus_tag="NOB31_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HCI0972615.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(26205..27092)
                     /locus_tag="NOB31_000372"
     CDS             complement(26205..27092)
                     /locus_tag="NOB31_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCI0972616.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(27181..28404)
                     /locus_tag="NOB31_000373"
     CDS             complement(27181..28404)
                     /locus_tag="NOB31_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI0972617.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28421..29467)
                     /locus_tag="NOB31_000374"
     CDS             complement(28421..29467)
                     /locus_tag="NOB31_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCI0972618.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(29631..31358)
                     /gene="ptsP"
                     /locus_tag="NOB31_000375"
     CDS             complement(29631..31358)
                     /gene="ptsP"
                     /locus_tag="NOB31_000375"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HCI0972619.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILARLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31358..31624)
                     /locus_tag="NOB31_000376"
     CDS             complement(31358..31624)
                     /locus_tag="NOB31_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HCI0972620.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            32103..34337
                     /locus_tag="NOB31_000377"
     CDS             32103..34337
                     /locus_tag="NOB31_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0972621.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34485..34805
                     /locus_tag="NOB31_000378"
     CDS             34485..34805
                     /locus_tag="NOB31_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCI0972622.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(35010..35234)
                     /locus_tag="NOB31_000379"
     CDS             complement(35010..35234)
                     /locus_tag="NOB31_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HCI0972623.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(35432..37012)
                     /locus_tag="NOB31_000380"
     CDS             complement(35432..37012)
                     /locus_tag="NOB31_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HCI0972624.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(37413..38789)
                     /locus_tag="NOB31_000381"
     CDS             complement(37413..38789)
                     /locus_tag="NOB31_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCI0972625.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(38917..40035)
                     /locus_tag="NOB31_000382"
     CDS             complement(38917..40035)
                     /locus_tag="NOB31_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0972626.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            40177..40611
                     /locus_tag="NOB31_000383"
     CDS             40177..40611
                     /locus_tag="NOB31_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0972627.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(40689..41222)
                     /locus_tag="NOB31_000384"
     CDS             complement(40689..41222)
                     /locus_tag="NOB31_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HCI0972628.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(41316..42494)
                     /gene="mutY"
                     /locus_tag="NOB31_000385"
     CDS             complement(41316..42494)
                     /gene="mutY"
                     /locus_tag="NOB31_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HCI0972629.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(42487..43284)
                     /gene="recX"
                     /locus_tag="NOB31_000386"
     CDS             complement(42487..43284)
                     /gene="recX"
                     /locus_tag="NOB31_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HCI0972630.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            43391..44773
                     /gene="rlmD"
                     /locus_tag="NOB31_000387"
     CDS             43391..44773
                     /gene="rlmD"
                     /locus_tag="NOB31_000387"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCI0972631.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(44947..45525)
                     /locus_tag="NOB31_000388"
     CDS             complement(44947..45525)
                     /locus_tag="NOB31_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HCI0972632.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            45847..46317
                     /locus_tag="NOB31_000389"
     CDS             45847..46317
                     /locus_tag="NOB31_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HCI0972633.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(46425..47651)
                     /locus_tag="NOB31_000390"
     CDS             complement(46425..47651)
                     /locus_tag="NOB31_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI0972634.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(48405..48605)
                     /locus_tag="NOB31_000391"
     CDS             complement(48405..48605)
                     /locus_tag="NOB31_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0972635.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(48739..49347)
                     /locus_tag="NOB31_000392"
     CDS             complement(48739..49347)
                     /locus_tag="NOB31_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HCI0972636.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(49432..49902)
                     /locus_tag="NOB31_000393"
     CDS             complement(49432..49902)
                     /locus_tag="NOB31_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HCI0972637.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(49950..50864)
                     /locus_tag="NOB31_000394"
     CDS             complement(49950..50864)
                     /locus_tag="NOB31_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI0972638.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            51010..51813
                     /locus_tag="NOB31_000395"
     CDS             51010..51813
                     /locus_tag="NOB31_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HCI0972639.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            51991..52938
                     /locus_tag="NOB31_000396"
     CDS             51991..52938
                     /locus_tag="NOB31_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HCI0972640.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(53006..53299)
                     /locus_tag="NOB31_000397"
     CDS             complement(53006..53299)
                     /locus_tag="NOB31_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HCI0972641.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(53327..53992)
                     /locus_tag="NOB31_000398"
     CDS             complement(53327..53992)
                     /locus_tag="NOB31_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HCI0972642.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(54132..54764)
                     /locus_tag="NOB31_000399"
     CDS             complement(54132..54764)
                     /locus_tag="NOB31_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0972643.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(54771..55838)
                     /locus_tag="NOB31_000400"
     CDS             complement(54771..55838)
                     /locus_tag="NOB31_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0972644.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(55835..56566)
                     /locus_tag="NOB31_000401"
     CDS             complement(55835..56566)
                     /locus_tag="NOB31_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HCI0972645.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(56735..57214)
                     /gene="greA"
                     /locus_tag="NOB31_000402"
     CDS             complement(56735..57214)
                     /gene="greA"
                     /locus_tag="NOB31_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HCI0972646.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(57350..58525)
                     /gene="mltG"
                     /locus_tag="NOB31_000403"
                     /pseudo
     CDS             complement(57350..58525)
                     /gene="mltG"
                     /locus_tag="NOB31_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
     gene            58729..59898
                     /locus_tag="NOB31_000404"
     CDS             58729..59898
                     /locus_tag="NOB31_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCI0972647.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(60165..61787)
                     /locus_tag="NOB31_000405"
     CDS             complement(60165..61787)
                     /locus_tag="NOB31_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972648.1"
                     /translation="MNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAFHINR
                     ALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLYIVTL
                     ITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPLILLG
                     FIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIFLIIK
                     LIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLS
                     FGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQA
                     PWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEM
                     NFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEI
                     TFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSY
                     TFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT        18107 a        12850 c        10352 g        20486 t
ORIGIN      
        1 ttcctatcct tccgcctatt tacattcatg cttcattgta cccaaaaact tcttaataaa
       61 aaagaaaaaa tgggcggagc aagaaattct ttacctaatt tcaagataaa atcaactttt
      121 tgtttcacag caatcactta aagttacata tccaactatt tttttcatta aaaaataaac
      181 ttatttttga aaattatgtt ttcttaagtc gtgaaacact ttgatggatc atttatttgt
      241 ggaaaactac gttttgttat tctaaaaaac ttatataaaa aatagtaagg tttttatttc
      301 gaatccataa aatattcttg gattgcttct cgtgtttttt tcactttttc gctaagcttt
      361 tcgtttttag ccatatagaa ataaaaaatg atatcgatcg tagcaaattg ggccaaaagt
      421 gaattagttg ccgcacttcg attcgtgatt tcttttggtc tagatgtttg tacgagtaca
      481 tcggctatct tgctaagcgg gttatttcca aattgcgtca acgcaatgat ttcgatattc
      541 atgcttttcg ccagctcggc taatgcgact acatctgcac ttctacctga gtttgaaaca
      601 agccaaagca ctttcttttt ctcattgctg acaagttgcg ggagcaagac gtggatatct
      661 ttttcaaaaa tgattggctt accgacacga gaccattttt gcagaatatc ttctactact
      721 aaagaagagg cgccaacccc atataaaaaa acagtctctg ccgattccaa acactctacg
      781 actttttgga tcgtttcttc ttctagaata tctactgttt cttttatcgc tacttgtgca
      841 ttgttaccaa gtttgttttt gatagagtaa aaggactcat ttgcttctat atcactaaaa
      901 ccttcatcga ttccagtctg tagttctgtt gaaatcgtga ttttgaagtc cgtcagactt
      961 tgaaaaccga tttttttgga aaaacgtaca actgtcggcg cactcaaccc ggaagcttct
     1021 gctaattcat tagctgtcat tgtagggacc ttctcaatat taccgataat gtagttggcc
     1081 aacttttttt ctgctgaaga ataatcttcc atcatacttt caatacgact aattacgctc
     1141 ataagttcct ccaccctttt aatgatagtc tatgtaagta taccatatca gacccttatt
     1201 cacggtcgta tactggataa aaaacaaaaa aacaatccgc ccaacagaat atcttatccc
     1261 atcaatccca cagattctat tgagcatctg tgtctttgag gaatacctgt tatctattgt
     1321 tcggattgct ttctatctac tactttttta caggaaattt acctattagt tttctctgct
     1381 gtaatttttg acttctgctt ccatagcatc aataaagata ttcaaatctt ctacagctgt
     1441 ttctttactt ccataacgac gtacgttcac tgttgcatct tccaattcct tgtctccaac
     1501 aactaattgg taagggatct tttgtgtttg agaggcacgt atcttatagc ccattttttc
     1561 attacgatca tcaacttcta cacgcaaccc cttcatttgc aaacgttctt tgatttcata
     1621 agcataatcg ccatgtgcat caacagaaac agggatgatt gttgcttgta taggtgccaa
     1681 ccatgttgga aaagcgcctt tgtatacttc tgttaaataa gcgacaaaac gttccattgt
     1741 agaaacaatt ccgcggtgga taactactgg acgatgcgta ttttccccgt cttctccaac
     1801 atatgtcaaa tcaaagcgct ctggcaataa gaagtctaat tgtatagttg ataatgtttc
     1861 ttctgtacca agagctgttt tgacttgaac atctagtttt ggtccgtaaa aggctgcctc
     1921 gccttctgct tcaaagtaat ctagttctaa ttcatccata gcggctttca gcattgcttg
     1981 ggctttttcc cacattgcgt catcatcaaa atatttatct gtattgtttg gatcgcgata
     2041 gctcaagcgg aaacgataat ctgtaatatt gaagtcagca tatactgcca ccatcaattc
     2101 aagcgtacgt ttaaattcat ctttgatttg atcaggacga acaaatgtat gaccatcatt
     2161 caacgtcatt tctcgtacac gttgtaaacc tgacaaagca cctgattttt catagcgatg
     2221 catcattcct aattcagcga tacgaattgg taattcacga taagaatgga tcgtgttttt
     2281 gtagaccatc atgtgatgag ggcagttcat tgggcgaaga acaagcattt cgccatctcc
     2341 catatccatt ggcgggaaca tgtcttcttg ataatgatcc cagtgtccag atgttttgta
     2401 caactcaaca tctcccatta ttggtgtata tacatgttgg taacctagac taacttcttt
     2461 gtctacgata taacgttcga tcgtgcgtcg gattgttgcc ccttttggaa gccagaatgg
     2521 caaaccagaa cctacttctg gggaaaccat gaacaagtca agttcttttc ctagtttacg
     2581 atggtctctt tcttttgctt cttcacggag acggatatat tctttcaaag ctttcttgtc
     2641 aaaaaaggct gtcccgtata cacgttgcat catttgattg tttgagtttc cacgccaata
     2701 agcacctgcc actgataata atttaaatac ttgtatacgg ccagtggatg gaacatgtgg
     2761 tccacgacac aaatcgatga attcgccttg ttgataagca gtaatcactt cttcttctgg
     2821 caattcacta atcagttcta ctttgtacgg atcacttgca aaaatttcta atgcttcctg
     2881 ttttgaaaga acacggcgtt cgatcggcag attttctttg acgattttca tcatttctgc
     2941 ttcgattgcc ggcaaatctt ctgcagttac ttggttttgt ccattatctg tatcgtagta
     3001 aaaccctgaa tcgatagctg gtccaacgcc aaagtggata tttggataga ggcgacgcat
     3061 ggcttgggcc atcaaatgag ctgctgaatg acggactaag ccaagtgcat cttcatggtc
     3121 tggtgtgatg atctcaatac ttgcatcttc ctcgattgga cgagtcaaat caacgagttt
     3181 tccgttcact ttaccagcta aagctttttt tgctaagctt tttgaaatgc tttcagcaat
     3241 tgccaatgtt gttgttccag actcaaattc tttgactgca ccatctggaa aagtaatttt
     3301 tatcataata gtttcctcct tgaaatgttt tgattgatca gatcatcaag ctgaaaaaca
     3361 aaaaaatcct agcatctctt gaaaagagat actaggacga aaagttcgtg gttccaccta
     3421 atgttcaaac gcaaatgcgt tcctcaagcg ttgtaacggt ccgaccgccc ttgcttcaac
     3481 aagggtttcg aaagtggtca tcctttggtt ttctcctgga aaagtttcag cctagctttt
     3541 cctctcttat cgaagactct caaattcagt tggctttctc atcaatcaat tatgtgttta
     3601 tttaaccact aataaataga aaaatcaagt gggaaactaa acttattttt tccattcccc
     3661 atttacaccg tatgttcctt ttttcatctc attgatgatg acatggatgt gttcttttgg
     3721 tgcctgcgtg tttttatgaa cagcttccgt gatatctttc atcatatttt ctaattgttc
     3781 cggactgcga ccttctacta attcgacatg tacgaatggc ataatgctct ctcctctttc
     3841 tgatcgttct tttttcaact cgattctatc atactatgtt tgtcttgggt actgaatcag
     3901 gaaaaatggc tggatctttt tttgctctca aggcactcaa aatagagacc gtatccacga
     3961 cttcttgcaa aacagctccg aataatgcgg ggattagtcc cgtacttgca attaacatca
     4021 aaaaaataca aataaagatg ccaatcagta cagactgttt cgctattctc atcgtatctc
     4081 ttgaaatcac tactgctttt gctacacgca agagatcatc tttcaagatg accgcatctg
     4141 cactttcact agcagctgta gaaccatgag cccccattgc aataccgata tctgcagcag
     4201 caagtgctgg tgcgtcattc acgccgtctc ctaccatcgc aacaggtctt tgatctttag
     4261 ggatactttc taaaatggtc agtttatctt gaggcaagct acgggcatgt acagaatcta
     4321 attggacttt ttctgcaatc gtttgagcaa tggcagatcc atccccggtg atcatcatca
     4381 aatttttcac atcaagtttt cttagctcct tgattgtctt tgctgcttct gggcgaatct
     4441 gatccgaaaa taggatcgtt cctgcaaaag atcgatcaat tgttacatag attgctgtat
     4501 tggacgtttc tatttcttca gctgaaacaa aagaggcacg tccaatcttt acttcatgat
     4561 tattgactac tgcttggatt ccttgaccgg tcacttcttt cagttgacta acaggataca
     4621 gttggctgtt tttcacgttg ttcactaacg aacgagctaa gatatggcta gattcctgtt
     4681 ctgcactagc tgcatacaga agtagctctt ctttttttat tccattgact ggctgaatcg
     4741 cctctacttc caatatccct ttggtaagcg ttcctgtttt atcaaaagca atcgtttttg
     4801 tacgtgcgag cttttcaatc gttgttccag tttttacaac gatcccgttt ttacttgaac
     4861 ggctcattcc tgcaactaaa gcaatgggcg cagctagaat cagtggacaa ggtgatgcca
     4921 ctaccagtac ctcagcaaat cgtaaagggt cttttgagaa ccaccaagaa ataccaccga
     4981 tcaaataagc aatcaacgtg aaagggactg cataacgatc agctaaacgg acaaatcggg
     5041 caggcttttc ttttgattct tcgactagtt taataatcat ttgatactgg ctgtctgcgg
     5101 cacgtttttc agcgatcatt tggatcgatc cgtctccatt taaagaccct gacataatct
     5161 gatctccagg tttcttggtt tccgggcggg actcacctgt caaagaagat tcatcgaccg
     5221 aagattctcc tttggtcact cgaccatctg cgggtacaag ttcgccaggc ttgactagta
     5281 actggtcatc aatatttatt tcatcgatta ctatatcctg caattttcct tctttgaatc
     5341 gatgggcaat tcttggggtg ttatctaaca aagactgcag ttctttaccc gctcgtttat
     5401 tcgcgtaatc ctctagacta tctccgcccg taagcatgat caatatcatc aaactagccc
     5461 agtattcttt gacggctaat gttgcaagga ttgcggtaat cgctaataca tctacgccat
     5521 atcttcctga acgtaacgtc ttgatcattt ccaaaaacat caagaaggcg agaatccctc
     5581 cagtaaatgc gacaatcgca aatgcaaggg ccggctggtg aaaaacaaat tcacttaata
     5641 aagctatccc accaataagc aaagtaagta aaaatttttt gaaatgtgtc attgtttttt
     5701 ctcctctttt atgtgactta gagaggttag taataaattt ccagctgcct ctttcatctt
     5761 aagcatagtc cttgactagc actttttaaa acaataggcc ttaattgaaa acaactatca
     5821 ctatcagcgt ttccaaaatt catcagttct acaaacaaaa atattcagca aggattactt
     5881 tttcgattca tcagttaaaa agtacctttt ttcgaaaaac tatgctatac ttttaattcg
     5941 ttatttacgg cggaaggagc aaacatgcga tgaatgagaa acaactagaa caaacgcacg
     6001 tggatgaaac gatcgaacta atccagatcg aacaaaatat gctggataca aaacaacaag
     6061 aattgactca ggaaatgaat cattcgacaa aagacacagc taatcacaag attcgagctg
     6121 gttccaatga agctttttat gaatctgctg ttgaatatcg ccaacatgag caggaattgc
     6181 ttttgaaata ccatactctt gaagcacagc aaaaacgcct gcaaacgttg tctgtcatga
     6241 aagatagtcc ttattttgcc cgtatcgact ttaaagaaga ccgtgaaaca gaaacattat
     6301 atctaggtat cgcttcttta agagatctgg cagaagaaac aatcgttatt gactggcgcg
     6361 caccaattgc caatctttat tatgaaggtg agattggtcc cgcattttat gaaactgaaa
     6421 cagatagaat agatgtcgat ctgcagttga aacgacaatt taaaatccaa gaaggacgta
     6481 ttttatctat ggtagatacg tcggaagtaa tcaatgatga ctttttgcta gagatattgg
     6541 atgaatcatc aagcaaccat atgaaaaaca tcgtctctac gatacaaaaa gcacaaaatg
     6601 caatcattcg ggacacaaca agtaaagtaa tgctgattga aggaatcgcc ggaagtggaa
     6661 agacatccgc tttgcttcaa cgtattgctt ttctgttgta tcataatcgc aagtggctcg
     6721 aggctgaaaa cgttcttcta ttttcaccca accatttgtt ttctgattac atctcgactg
     6781 tattgccttc attaggtgaa agcggcgtgc ctacacagac attcaaaaat tatttggtgc
     6841 agctgctgcc agagttttct ttactagatg aacagcaaca agaaagtggt tttttgctag
     6901 gggaaaaaga tccgatacaa gtgatgaaaa gcggattgac cttagtcgat cagattgatc
     6961 gctatatcca aggcatcaca aactacggtc ccttgttccg tgatatgaaa ataaatggcc
     7021 gtacgatcct atcaaaggaa tcgattcgcc aatggtataa agaaacaaat gaacaattac
     7081 ctttacatca tagactttct ctattacaaa cgaagctcct gaaaaaatta ggcggtctgc
     7141 aaaaagacga aacacgtcag caatgggtca aagatctggc ggaagaacag ctccaagaac
     7201 tatacgcaac agatccaaat cttgaatata cagaacaaaa ggagcgttca ttacgtaaaa
     7261 aactggccaa ccaaatcgta cgtaaaagat tccgtcgaat ccatcgaggg atcatgaatt
     7321 atcaatttgt caatataacg aaacaatatc tccactttct acaaactgtg ccactttctc
     7381 ttctaacacg acataaaatc agcgagacca ggtggcagga acatttgaca actgttcgta
     7441 cacacttgcg tcaaagagaa ttgcgtcaag aggatgctgt actattcttt ttactgatgc
     7501 gccgaacata tccagtgacg gttacacaca aagctcgcta tatctttatt gatgaaatgc
     7561 aggatttcgc accatcacaa gtggcattgc tgcaagcctt gttcccaaaa gcaaatttga
     7621 ctttctgtgg agatctaaat caaaatgtct ttggaaatga aacgatcgtt ggatcattgg
     7681 aagacctttt cgtggaccgt gaagtcactc gtttccaatt aacgacaagc tatcgctcca
     7741 caaaagaaat cactgatttt gctaatcatt ttattgtgaa agaacatcaa gtagaaacaa
     7801 cagcaagaaa aggagacctt cctttgctca tccaaggaac aacagatgat atcaaattga
     7861 attggttagc agataccatt cgaacgactc agggaaaagc ccggtattgg cgtacagcaa
     7921 tcatagctaa aacacaagaa gaatgcgaag ctctttatgc tcaactgcca gacgagttga
     7981 aacaacaagt ccagctgatt ttaaatgaga gtgactttat gaagcgttcc attattttac
     8041 ttccagcctt tttagcaaaa ggtctggagt ttgaccgagt tttcttgtgg gatgtagatg
     8101 cagaacattt ttcttctcag caagacaaat tgatccttta caccatgtgt acacgtgcga
     8161 tgcatgaatt gacccttttt acctccaata atgaaagtcc tttgttaaac aatatggata
     8221 tttcatctta tgagaaaaaa gtactgtaag taaaaagaca actgctatca ttaatgttag
     8281 cagttgtctt tttatttaca ataataattg cagaaaaagt aattcaatca tttaaggtca
     8341 tttattctat atataaatcc aaatctgttt caggatattt taatttgaca agcgaaataa
     8401 tcattttcag ttcttccatg ttttctggat attctgggtc aaataccttg ctatgacggc
     8461 caatcccgcc attgtcgatc aatcggtaaa ttcgattcca ttcaatgaat tggtcaattg
     8521 attggaaatt gctgattgga tagccgccac aatccaaaat ctctgataca cgaaatgcta
     8581 ggtatgcact atcgatcact ttattttttt tcgtgtctat cttctcattt ctttcgataa
     8641 gaattttttc aggacgatgt ttcaagctcc actctaatag tagaaagaaa gcctccatcc
     8701 gatactcttc ttcaaataac cgaaaggctg aatcagaacg acgaaaaagc agcggaatca
     8761 gataattttg tctataaatc agcattggtg cgcggtccac catacactct aaataacggt
     8821 tcagataccc tgtaccgaca tagtttccta atcgatagcc ttcaacgccg aatcttgcgt
     8881 atttttgcgc taattttgaa caatcagtta cgttcacagc taactcttct actttgcggt
     8941 aaccgcttaa gatacgttca aaaggttcta aagtgatttt tgcttccata ttcttccccg
     9001 tccatcttcc acatacttca tatcatttca catgatactt atgctctcat cataccacag
     9061 gttgaattag aaaagaaaat aaatcacaca aaaaagcaag acaatctgtt agtgagattg
     9121 tcttgctttt cgaaaaagac tgaatacttt tcgttaaaac tggttgctta gtcttctaat
     9181 gccacattat ggaacacatg ctgtacatct tctagatctt ccagtgcatc aatcattttt
     9241 tcaaatgttt cttgatcttc tggagatagt gttacctcgt tttgagggat catttggatc
     9301 tcagcgattg aaaaatcagt gattcctttt tcttttaatg cttcttgtat actatggaaa
     9361 tccgctactt caccgtaaac gatgatttgt ccttcttctt ccattacatc gcgaacatcg
     9421 atgtcttttt ccattaggta ttcaaggatc tcgtcagcgt cttctcctgc aaaagcaaag
     9481 attgctgtat tgtcaaacat gtaagaaacc gctccggaaa cacccatgtt cccgccattt
     9541 ttcccaaatg ctgcccgtac gtctgctgct gttcgattca cattgttcgt caatgtatca
     9601 acaatcacca ttgagccgct tggtccaaat ccttcatagc gcaattcaga gtatgtttca
     9661 tctcctgcac cttttgcttt ttcgattgct cggtcaataa tatgttttgg tacattataa
     9721 gttttagcgc gatcaatgac gaaacgtagt ttttggtttg catgcggatc aggatcacct
     9781 gattttgctg ccgcgtagat ttcaatccca aattttgcat aaatccggct attattagca
     9841 tctttagcag ttttctttgc tacgatattt gcccatttac gtcccatatt ttcacttcgc
     9901 tttctgattt gatagtttca taacgcaaaa acgtcctgtt ccattatact tgtgaatcac
     9961 gattctgtga agcttttttt ctttcttcct tcattcttct catttttagt caattatcta
    10021 tactcggatt gggatttgcc cgaaattctg ttccggaata ttgcctccca attgatagat
    10081 ttgatcactt ctaactaaca gttccgcttc ttgtgcctct ttttttccga ttcgggaata
    10141 aatagaaatc tctttttttt cttttaagaa tcttcttcca gcatcggtaa atccaagtag
    10201 tcgaagataa tttttatttt gttggacagg aatctcttgc tttttgatat tcagcaagac
    10261 ataacaagat aatcgttgga tccgtgtcca tgtatatctt tttgttttta cctttgacac
    10321 aaaatcctca aaactatcag cagttgcagc tgctgttttc atgcgcgatt ctattccttc
    10381 ggtcatctga tagatatctg tcagttccag caaagtagaa gataacaacc gataacgcaa
    10441 atacggccaa taagattccc aagtctgcag cgaacaagtt gaaagatctt cttctgtctg
    10501 aggcggcaca agtccagcta ttctttttcc ttcttctaac gcatggcgaa tggctgttgc
    10561 actggctatc ctctgatctg tgatgatttt ttcatgatag cctgcacttt tacgtcggat
    10621 cggatgtaat tccatagggt ggacatactt ggcattttcc tttgcataac ttaatcccaa
    10681 gatatgattt ggcgaagaaa aatcaagcgt aatatcggga tacagactgc gaaaaacctc
    10741 agtcattttt tgcggataac tatacgtttg atcagacagt tcttgaaatg cctcttctat
    10801 cctatcttga ttctcttgga caaagcgtcc gaaactgctg taatcaaacg aagtctcttc
    10861 ttctgttcca aaacacaaac tgtcacagtc cagtgtttgc aagattttta ctgcaccttt
    10921 agcaaaatag tcagctgact gaaccgccca ttcgacggga agctccacta ctaaatccac
    10981 accattttgt aaagcttcat tcgcgcgatg ccatttatcg atgatagccg gttcgcctct
    11041 ttgcaaaaaa ttcccgctca ttacagcaat gacgacctct gctcctgtta tttttcgtgc
    11101 catttccaca tgatagcgat gtccattgtg aaaaggattg tactctacga taatcccgca
    11161 gcttttcatg cgcatcctcc ttcatagtta tcgataaaaa agaaatagag acaagtaaaa
    11221 aaaggcaaaa atcggaaaaa atacccgaac tatataaact attctcgcaa acacaatact
    11281 tctgcgacga aaagctgcac tgcaagagca atgcctatat cgttcggata tataatttat
    11341 gttgaagatt tattcttttc ttgttaactc gagcaggcaa aaccgctagt ctttgtatgc
    11401 tacaaagaac cagcgctttg atttctctga tgctgcttcg tctgtaaaat cagaaaatgc
    11461 ttcgactttc gaaaagccgc tgttttccag cattcttaaa taactttcca atggataggt
    11521 acgctcttga tgtagttcat cttcacgaat aaatcgacca gacccttctt gttcttcaac
    11581 gaaaaaggta agaaaatgtt cgatgctgtg tttctcgctt cctggataac tatcccacaa
    11641 aaaagcaaaa ttatcccctt gataatgata gctatattct ggaaaaacct catctacttg
    11701 ataggtggag tgtacgtcaa ataaaaatcg gccattttct tctaacgctt gatagacttc
    11761 atcaaacact tgctgtacct cttgtctatt tttcatatag cacagcgaat cagaaaaaca
    11821 ggtaattgcc tgatattgtc cgatttctga taaatcgagc atattgcctt ccacaaattg
    11881 gatcgatgcg tcttcttcat atgctcgctg gctggcaatc atcaacatct cttctgaaag
    11941 gtctaaccct gtcactttat atccatcttt tgcaaaggca accgctaatg ctccagtacc
    12001 gcatgccagt tccaaaatat tttttgtgtc ttcttgtaaa tgacgtttcg aaaaagctaa
    12061 ccattgctga taaagtgttt cgtccatcac ttcatcgtaa atgaaagcaa atgtttcata
    12121 agccatatgt taatccaacc attcactaag atcgactagc ggagcatctg accatagttt
    12181 ttccagatta tagaaatttc gttctggcgc atggaaaaca tgtacgatca catctccaag
    12241 atcgatcaat acccattttc cgccttcttt tccttcaata cgttttactt catatttgtt
    12301 ttcttcttct ttatcaatga tttcttctgt aattgcgttg atttgacgtt cgctatttgc
    12361 tgaacagatc atgaaataat ctgccaacaa ggaaacattt cgaacgtcta aagcgataat
    12421 gtcttctgcc cgttttgaat ctgctgcttc aatcgcaatt tttaattgtt ctttactatc
    12481 tatgatgatt tcctcctaat atgagcagct tatttttttg ctacccagta attatatgtt
    12541 tcgattgttt ttggataaat ctgttgttct tgcgcaagca aatgggccaa tgtatgtttt
    12601 gtttcaaatg ctacagcttc gtctagatca gcccatgcaa tggctcgtgc atcttgtacc
    12661 ccaggaaaat ctcgacctgg ttcaatatag tctgctacat aaatgatttt gtcaaggaga
    12721 ctcatcttag cagccccagt cgtatgcacc cggattgcat gaagaatctc tgcatcggtg
    12781 attcctaatt cccgctctac aaacgaagcg ccaacaagac catgccagat tgcattatta
    12841 taattcaata actccggatc aaaaccgtct cttacgatta ccattttgaa ctcctcatct
    12901 ggtcgttctt ttgcataatc atgtgtcaat gcagcaatac tagctttttc aggagaagca
    12961 ccgtattttt tggcaagagc cacggctgtt tcttctactc caagcacatg cttgaagcgt
    13021 tgttcgctca ttctcatctg tattttttgc atcaggtttt ctctagaata agcagtatat
    13081 tcattactat agtccatatt catacaaccc ttcattttga atataatcaa ttactttatc
    13141 tggaacaagg tagcggatag aacagccttc tttgatcttt tgacgtattt tcgtggaact
    13201 gatgtcgatc tcaggtacat ctacccaaat tacaggatat ggagtatccg ttgtgtatcc
    13261 tggtcgacgt atacccacaa agttgaccat agaagtcagc tcatcgattt tataccattt
    13321 tggcaaatat tctaccatat ccccaccgat aataaagtaa taatctgtat ccggattgtt
    13381 ttgcgtcaat tccttcatag tatcataggt gtaacttttc ccaccacgag ctaattcaat
    13441 cgtttcaatc tgcaaaaaag gattgtcttc caccgctaat tccaacatgt tgagtcgatg
    13501 ttttgcatca atcgtctgtt tctcatcaac atgaggtggc tgataagaag gcatcaaaaa
    13561 tacgcggtca agacctaaat tccggccagc ttgttcagcc atcactaaat gtgcaaggtg
    13621 aacgggattg aatgttccgc ccaagatccc tacttgcttt ttcttctcta agaattgagg
    13681 catttcttca ggaaataatt gtgaacgaac aaatgtctta gcttgcgtat tcatcatggt
    13741 cactccttat attgctttta cttcttttga tagcctttga tacttttctt ttgtggaagg
    13801 tttgtataat acaataacac gtccaatgat ttggacgatt tcgcaatcta tttctttttc
    13861 taatacttga gctgcttctt ctgcaatctc atctgtattt tgaagtaacg atactttgat
    13921 cagttctctt ttttctaaag cttcttcaat ttgaacgatc attgctgaat tgatcccacc
    13981 ttttccgatt tgaaaaatcg gctgaagatg atgcgctttg ctacgtaaaa aacgcttttg
    14041 ttttcctctt aaactcataa ttttccttct tccttaaatc aatgctttgc gtttcaatac
    14101 atctacaccc tttggcgccc agcccgcaat tactactggc gctgttacag tgatccagcc
    14161 tagaccggca aaaacgatgt ctgttttttc tttcacagaa aactcaaaac gaacaagctc
    14221 cggaaatgcc tcgacttcat caggacgagg aggctgtaat aatccaccta catgtttttg
    14281 ataaaattcg tctgcttttt ccagtttcgt tcgatgaata tttacatcat ttgacacata
    14341 agcaataaat gaagcacgat tgccgctgat aaaatcaaat cttgcaagtc cgcccaagaa
    14401 aagtgtttgc ccttcattca gctgataaac tttaggtttg atttctttta acggtgcaat
    14461 gatccgcaaa tcttttttac ctaagtagtg cgccatttga tggcgatgga taattcccgg
    14521 tgtatcaatc aaaaaatgcc cgtcatctaa aggaatctcg attttatcca aggtcgttcc
    14581 tggaaactgc gaagttgtga ttacatcttg tactcccgct gtatttttga tgatttgatt
    14641 gataagcgtc gattttccga catttgttac tccgacgata tagacatccc gtccatcgcg
    14701 gtattcttcg attttttcta atagttccgt catctcatga gatttcttag cactagttaa
    14761 taatacatct actggacgaa ttcctgcttc gtaagcacgt tccttcatcc attgtgttaa
    14821 tttagttttt ttcaatgatt taggtaatat atccactttg ttcccaacta aaagtactgg
    14881 attgtcaccg acaaaacggt gtagtcctgg gattagtgaa ccattgaagt caaaaatatc
    14941 caccacattg acgatcaatg catctttttg ccctaattca ttcagtaagc gcaaaaagtc
    15001 gtcatccgtc aatgagacat cttgggtctc attataatgg cgtaatctga aacaacgctg
    15061 acaatagact tccccggaag ctaaaccttt ttccaaagcc gtttgcggcg tgtatcctaa
    15121 ttcaccgggt ttgtttgttt gtataacggc accacagccg atacattgta attcttctgt
    15181 cattcgattc cacctcgcca gcccatatca gggtgttttg ctaatagata ggccataatt
    15241 cttttttccc aaaaacgatt aaattgtgtc ttccaactat ctgttgcgat aatgggtttt
    15301 acaaggatgc tacgtatccc tgcacgattg gctccacgta tatcagtcat aatctgatcg
    15361 cctaccatta ctatctcatc atctgctaaa tccaattgtt tctttgctat gttgatccct
    15421 cttgctaaag gtttcattgc tcgtgcaaca tacaaaagat caaatttttc aatcgctcgc
    15481 gcgacacgtt ttgaattatt gtttgaaaca acaacaacag ggattcctgc atttttcatt
    15541 tctaaaatcc aagtaagcaa ctcttctgtt ccatctggat tattccatgc aatcaacgta
    15601 ttgtctaaat cggtcaatac tgctttgatg cctagattct ttaattgggc aggtgtaatc
    15661 tgatagatgg cttctaccat ccatgttggt ttgtaatttg aaaacatgct gtctcctcat
    15721 ctgcaaaaaa tgaaggagca cataaagtac tcctcaaccc cgtattatac tgcatatcag
    15781 caaaaaaaac tacctctata ctcgttcgtc tttcagaaaa agcatttctt tacaaaatga
    15841 ccaaaaataa agattgatca cagaaaaatt tagaaacaaa aaacaactaa tattggcgga
    15901 acctcttgta tcgtttttcc agtaatttat gctgatctaa tcgaacaagt tccgtcaatc
    15961 tttcaatcaa cgcttttttc ataatgtgtg cgactttata tcgtggcaac tgctcgccgt
    16021 tgaacgtttc aggaataact cgatcaacga ttcctaactc gcgtagttct ggcgcagtaa
    16081 ttttcatcaa ctcagctgct tctgcggcgc gactaccgtc tttccacaaa atcgacgcaa
    16141 atccttctgg agaaagcaca gcataaatcg tttcttccag catccagact tcatccgcta
    16201 aacctagagc aagggcaccg ccacttccac cttcaccaat gatgatggcg atgatcggta
    16261 cctttaaatc agacatttcg agcagatttc tggcaatagc ctctccttcg ccgcgctctt
    16321 ctgctcctac accgcaatat gcacctgctg tattgatcaa ggtaatcacc ggtctattga
    16381 acttttccgc ttgtttcatc agtcgtaaag cttttcgata gccttcagga tggggagaac
    16441 caaaatttct gcggatattt tcctgcagat cccgtccttt ttgaataccg atcactgtta
    16501 ccggtttgcc atctaatcga gcgattccac caacaatcgc ttcgtcatct gcaaataaac
    16561 gatcaccatg gcattcctcg aaagaatcga agatctcttc aaaaaaatcc aagcttgtcc
    16621 atcgttcttt agctcttgct aactgaacga catcatgtgc tgtcttatcc acgatctatc
    16681 catcctttct gtgtatgcaa ttcaagaagc gtatggattt tctgtttcaa ttccatgcgg
    16741 ggaacaatct gatcgacaaa accatgagat aataagaatt cagccttttg gaaatcttct
    16801 ggaagttcct gcttgatcgt ctgttcgatg acgcgtcttc cagcaaaacc gatcaagctt
    16861 tggggttctg ctagaataat atcgccttcc attgcaaaac tggcagttac tcctccggtc
    16921 gtcgggtccg ttaaaacagt tagataaaaa agaccttcat tgctatgccg tttgacagca
    16981 gcagagattt ttgccatctg cattagagaa aagattcctt cttgcatccg tgcgccacct
    17041 gaagctgtga acaagacgac tggaagactt tcctttgttg ctcgttcgaa taatctggtg
    17101 atcttttctc cgacaatcgt tcccatactt cccatgataa aattaggatc catcactcca
    17161 ataatgaagg gaatcccctg aatggttgct ttaccagtga ggactgcttc atgaagtcct
    17221 gttttatctt gcattttttt aattttttcc gtatattcgg gaaatgctag cggatctttg
    17281 gttacaagat ccgtatccca ttcttcaaaa cttttttcat caataatcaa agctagacgc
    17341 tgccatgcac cgattcgaaa agcgtatccg caatgagggc atactttttc ttcaccgatg
    17401 tctttcgtat aaaggatatg tttgcaattt ggacactttg cccacatgtt atcaggaaca
    17461 gatggcgagt tagcaggttt gctctctcta ttaggattga tccgaatata tttctttttc
    17521 ttaaacagag ccatctatgc gcctcctatc tccgtttctg gtgtccaatt cggtaaaaat
    17581 tcttcttgta aaaatgctgt gctgtaatca cctgctatga ctgcaggatg actaatcaaa
    17641 tccatctgaa attctgcgtt cgtgatgatt ccttctgtga taaattcact taaggctcgc
    17701 tgcatcttca ttaatgcttc aaaacgcgta tttccatgga cgattatttt tgcaatcatt
    17761 gaatcataat atggcgggat cgtatatccc gggtaaactg cactgtctac tcgcagtccc
    17821 atcccacctg ctggaagcag taagttttgg atcttccctg gagaaggagc aaaatggaaa
    17881 gcaggatttt ctgcattaat ccggcattcg attgcgtgtc cttggaatac tacttcttct
    17941 tgacacacat tcaaaggctc accggctgct atctccacct gtttttttac taaatcgatt
    18001 cctgtgacca tttctgttac tggatgttcc acttggattc gagtattcat ttccatgaaa
    18061 taaaaatcgc cttcttcatc catcagaaac tcgatcgttc cggcattttc ataattgact
    18121 gctttagctg ctcgaacagc agcgtctcct agtgcttctc tttttgtttg tgagatcact
    18181 acagaaggag attcttccag tactttttga ttgttgcgtt gtaaagaaca atctcgctcg
    18241 cctaaatgaa tgacatgacc aaatcgatca cctaagatct gaacttctat atggcgagca
    18301 ggataaatga ttttttccaa atacatatca tcatttccaa atgccgctgc tgcttcttgc
    18361 tgagctgaag aaaaatgctg tgggagctct tcttttgatt gaactttccg aatgcctttc
    18421 ccgccaccac ctgcagctgc tttcagcatc actggataac caattctgtc tgctatttcc
    18481 aatgcttctt ctactgtaga taatacacca gtacttcctg gaatgactgg gacatttgct
    18541 tcttgcatca attgacgcgc attgatctta tttcccattg catcgatcgt tgcactttta
    18601 ggaccaataa atgtgatatt gcactcttca cacatggagg caaatcggct attttcagat
    18661 aaaaaaccaa atcctggatg aattgcttcg gcttttgtca cgattgcagc gctcagtact
    18721 tcctgaacat tcagatatga atcaacggct tttgccgggc caatgcagat tgcttcatct
    18781 gctaactgtg tatgaagtgc ttcggcatct gcttctgaat atatcgctac ggtttggatc
    18841 cctagttcgc ggcatgcacg aatgatacgt acagcgattt caccgcggtt agctatcaat
    18901 actttagaaa acatatttca cctatccaat cataaaggtt aattccgctt cggctacttt
    18961 tttaccgtct actttagcga ttcctttgcc tattccggct gaagctttca ctttcaatat
    19021 ctcaacttca aggtataagg tatctcccgg tgtaactttc ttacggaatt ttgctttgtc
    19081 caatccgccg aaataagccg tctttccctt gaattgttca agagaaagta atgcaactgc
    19141 tcctgcttga gccattgctt caacaatcaa tacccctggc ataacaggtt cttctggaaa
    19201 atgtccttga aaaaagggct cattgatcgt tacatttttc ttagcaacga tccgttctcc
    19261 ttcaaccatt tcttccactc gatcaatcaa aagcattgga taacgatgtg gaatgatttc
    19321 ttttatttct tgtatgttca ttgttttccc tctttcctgc tttgcttatt tttgctgaat
    19381 cctaaagagt ggctgtccat attcgacaac tgactcgttt tctacaagga tttctgtgat
    19441 cactccgtcg gcctcactag ttatctcatt catcagtttc atcgcttcaa taatgcagat
    19501 aacttctcct ttggcaactt gatcacctac ttttttgaaa gctggtttgt cgggcgctgg
    19561 ttgcagataa acgattccca cgattggcga aacaacctcg attccatcaa atactgccga
    19621 ttctttttct ttcattattt ctggagcagt tgttgcttgt tcaggtatga cattgactgg
    19681 ctccgaaact ggcaacgttt cgtttgtttg aaccatattc atgcctcgac ttgttttatt
    19741 tttattcata tacaattcaa attgaccttc acgcaaatcg aattccgtta gcgaggattg
    19801 atcaaattga ctgactaatt ctctgatttc attgatatcc aaaattattc ctcccagcgt
    19861 ttcatgcaca gaaccgcatt atgtccgcca aaccctaatg aattactcat tgcataagta
    19921 aaacttgcag gtttgctttc gtttttgaca actgtcaagt caatctcagg atcttgtttt
    19981 tctacattga tcgtaggtgg gataaattga tgttctaatg ccagcaaagt tgccaaggct
    20041 tcgatcccgc cggctgctcc caataaatgt ccagtcatcg atttcgtgct gctgacgtaa
    20101 gtatctctga aattttcacc taatgcgatt tggattgctt ttgcttctgc ctggtcattg
    20161 gctggtgtac ttgttccgtg agcattgata tatccgactt gttccggctg tacaccagct
    20221 tcttccatcg caagcttcat tgctttagat gcaccagaac catctggagt aggagctgtc
    20281 atatggtaag cgtcacagtt tgcaccgtat ccaacgattt ctccatagat tttggcaccg
    20341 cgagcttgtg catgttctaa agattcaaga actagaacgc ctgctccttc acccatcaca
    20401 aaaccattcc gattttcgtc aaacggaatc gaaccacgat taggatcagt tgattctgag
    20461 agtgctgtta aagctgcaaa tccagcaatc cccatctcac aaatcgttgc ttctgttcct
    20521 ccagcaagaa tgacatcaga atagccatgt ttgatgttac ggaatgcttc cccaattgaa
    20581 ttcgttccgc tagcacaagc tgttacgata gctgtacaaa taccttttgc acctacacgc
    20641 aaagcaatat ttccagctgc catgttggca atcgccattg gtacgaacat tggagaaact
    20701 cgttttgcac ctttttcatg tagacgaata acttggtttt cgattgttgg aagaccaccg
    20761 atcccagatc cgatgatgac gccaaaccgg tcttgattca ttttttcttt atctaaaccg
    20821 ctcatctcca ttgcttctaa agcagcgtag attccataga tcgaaaacat atccattcgt
    20881 ttgctatctt ttttaataaa atatttatcg taagggaaat ctttgacttc acccgctaag
    20941 gtaatccctg tttctgaagc atcaaattta gtgatcggtg cgatgccatt cgtcccctct
    21001 tttaagctat tcaaaaagct gtctgcgtca tttccaatag gtgaagtgac tccatagcca
    21061 gtaattacca ctcgattcat ttgtttgctc tccttttctt atccgtgcat gaccaatccg
    21121 ccatcgacat tgatgacttg tccggtgata tatggatttt gtgctaagaa aactgctgtt
    21181 tgtgcaatat cttctacttg tccgaaacgc tgcatcggaa tttgcttttc cgcttgttcc
    21241 ttgactttgt ctgctaaaac ttccgtcata tcagttgtga tgaatcctgg cgcaatggca
    21301 ttacatgtaa tgcctctagt tgcagcttct cgtgccacag attttgttaa tcctactacg
    21361 ccagctttac tagctgcata atttgcttga ccaatatttc caatcaaccc agatacacta
    21421 gagagattaa tgatggcccc ttctcgctgc ttcatcattt ttttcaatac gtgctgcgtc
    21481 atattgaagg ttccaatcaa attgatatcc agacattttt tgaaatcttc tgcatccatt
    21541 cgcatcacaa gtttgtcatt tgtgattccg gcattgttta ctaacacatg gatcgatcca
    21601 agcttttctt ctgcttcttt gatcatttgt cccgctttct cataatcaga gatgtcaccg
    21661 gaaactccta cgcattttac accgaatgct tcgatttctt ctatcttttc ttttggaatc
    21721 tctccgcgac cattcaaaat gatatttgct ccagcttttg caaaagctaa ggccatcgct
    21781 ttgccgattc ctcttgtact acctgtgata aatacatttt ttccttttac atccataacg
    21841 ttcctcctta tagtattgct attgtttcat caaatgtctg cttattctca acacgcagaa
    21901 ctggtattgt tttatcgatt tttttcataa atccgcttaa tacttttccg gggccgactt
    21961 cgatgacttg ttcgatgccg attgttttta acttatggat actctcatag aaacgaacag
    22021 gttgcatgac ttgctgttca agtagtcccg cgattgtttc tttcttcatt atttccgttg
    22081 ttgtgttgct tatgatagga aaagaaggtt cagagaattg aatctgactt aggtccttcg
    22141 ccagtttttt tgctgccggt tctaaaatag ctgtatgaaa aggcccgctg acatttagag
    22201 ggatcattct tttgaaccct ttttctttta atagtaaaac agcttcgtct actgcttttt
    22261 cttcgccacc aatcacgatc tgctgaggtg tattataatt tgcaggagat acgatgccgt
    22321 acttgctagc ttcatgacag ctttcctcga tcgtttcaat cggcgcattc atcactgcaa
    22381 ccattttccc gcttccagct ggggcagctt ctgtcatata agcgcctctt tttgctacta
    22441 acgcaactgc ttcagtgaag gatagcgcat tactagctac taatgccgaa tattctccta
    22501 aactcagtcc taaagctgca tctgggatga ttccatgctc cttcaataag cgataatacg
    22561 cgatgctgac tgttagaata gctggctgtg tatattgcgt ctgatccaaa cgttcatttt
    22621 ctgtaaagca aagttcagcc atatcgtagc cgagaatctc acttgcttca tcaaatgtct
    22681 gctttacaac ggcttcttca tataaatctt ttcccatacc ttgatattgt gcaccttggc
    22741 cactaaataa gaatgctgtt ttcatgtttt tctccaatat atccagaata tatgtttgat
    22801 tcttcctatt caaaaaggcc gagacattcc tatttcagga aatgtcccag cccccaacct
    22861 aattttaatg attatgcagt ttgtttttct acgtaagtca ctaaatcttg aaccgttttg
    22921 attccgtctt ctgtttcgat tttcacgtca aattcatctt caatttcatt gatgatttgg
    22981 aataaatcca agctgtcagc ttctaagtct tcttggatgt cagtagtcaa tttgatttct
    23041 tcagtttctt ttcctaattc ttctgcgatg atttcttgaa ttttttcgaa taccataata
    23101 atatattcct ccgatattgt ttgcttttta tttttataat ttaacagtct acaactccat
    23161 gagaatactt ccccatgtta aacctccgcc atagcctgta aatattactt tctgctgttt
    23221 tcctaaggtg atctttccac tagaaactgc ttcatccaat aagataggga tgcttgcagc
    23281 agatgtattc ccatatttat ccatattggt caggaacttt tcttgcggca tctttacttt
    23341 tcgggcaatt ttctcaataa ttctgaggtt tgcctgatgc aaaagcagat aatcaactgg
    23401 tttgtctttc atgacttctt ggatattgtt tgcaacgtct cgtacggcaa aatcaaaaat
    23461 atctctgcca gtcatttgca aataatacga accttctgaa tcttctgaat agaacggatt
    23521 tttattttgc tggtagccag cggtcaatga gctacttctg gtaccgtcag ctgctaattt
    23581 ttctttcagc aattttttct gtggattcgc ttctaagaga atcccacctg ctccatcgcc
    23641 aaacaacaca gcagtcgtac gatcagacca atcgattagc ttagatagtg tttcaccacc
    23701 aatcaccagt cccttagttg agccgcagcg gatcattttt tcagccatgc ttaacgcata
    23761 aacaaatcct gagcacgcag cactgatatc aaaagcgata gcatgagttg ctcccaattt
    23821 cccttgtact tgtgctgcta cagatggtgt cgtgtaatcg ggcgacattg ttgctactaa
    23881 aataaaatcc aaatctttag ggtttagatt tttctgtttt atcaattttt ccgccactaa
    23941 aatgcataaa tcagaagtct cctgatttgt tacacatctt cgttcacgaa tacccgtcct
    24001 tgacgaaatc cattcatcag aggtatccat catcttggaa agatcattat tagtaataat
    24061 cttttcagga aggacgctgg ctgttgcagt aatcattcca aattgttcca ttaaatatcc
    24121 tcacttatag tcttgcaaga agtcgtgcaa gtttttcagt gcatccagca aggcatgctg
    24181 ttcctccgta gccattccgt ctaagatgtt cttgaccatt tcacgatgaa aatgctgatg
    24241 gacccgaaat agtaactttc cttttttcgt tagtcccaac tttacaacgc ggcggtcatc
    24301 ttcactgcgg atacgttcga catagccttt ttttactaac ttgttaatag cagtggtcaa
    24361 ggtcccaaca gtaattgata gttctttggc tacttctgaa gttgtttttt tcttgtacat
    24421 cccgattgcc tcgatcgtgt gcatctctgt gattgacaga tctttgaatt gagatttttt
    24481 cagctcagac tcttcgattg tcaaaatatc attgaagaca ctaacaagat aatcatttac
    24541 tgtttttaaa tctggttcca tgttccaccg tccactaatt agtttgatta tcaaatcttt
    24601 tgatgttcaa actatatctt aacttttttc aaaatgcaac cttaaaagat cattttttta
    24661 ctatatgagc tttttttaag attttactca tttaaaacaa ctgataaatc agcatttata
    24721 atttctttta ttagaaaaat catctatctc acatattttg attatcaaag tattttctgt
    24781 gaacagaact atagaattcc ctaaaacttg tccattattt caaaatttgt tatagtcttt
    24841 ttattcaaag cgtaaaagga gatcctatgt taaaagaaaa aatgaaaact ctccccatgc
    24901 tgccgggtgt ctatcttatg aaagaccgag atggtaaggt catctatgtt ggtaaagcaa
    24961 aacggctcaa aaatagagta agcagctatt ttcatcagaa taaacagcat tcaaaaaaag
    25021 tattacgtat gattcatcat ataacagatt ttgatttcgt cgtagtagac acggaattag
    25081 atgctttatt gctcgagtgt caattgatcc aacattaccg tcctttttat aaccgacaaa
    25141 tgaattattt cagtaattat aattatgtac atattaccaa taagggattt gtattaacag
    25201 atactcctac ggctcgaaca tacgggcctt ttcgtctcta taaaaaaatg ccgtctattt
    25261 tgcgtataat ggaagaaact tatcaaatgc cttggttgtc tgaaattagt ttgttagctt
    25321 tgcgagtcca gcttcctgac ctacaggaaa tgacttttga acagaaaaaa aaggaactcc
    25381 aagggctgtt tcaaggccga aataaaaagc tactgactta cttgaaaaaa agacaacaac
    25441 atttcatcta tcagttgaat ttcgaaaaag ccggtatgct tcaaaaagat atcgaattag
    25501 ttacttattt tattagacgg atccaggaac aaaagcagtt tttaagaaca ccatcgctca
    25561 ccttcagcat gccattagca gcagatgaga gtcagaaaaa gcactacctc gtttgttatg
    25621 gtcaacttgc agaaacaatg attacctctg gtgacgtttc tcctgacttc tattatgaaa
    25681 agaaagaagc tcatttatct ttgaaacgtc aattgtcaaa agaagaaatc gatcctgtac
    25741 aaatcttgat cagttaccgc aaaaaattag aaaaagaaca gtttgaaatt gaactgttaa
    25801 acaaaaaaga agctgaaaag caactaaatt agttgcttct cggcttcttt taggcatctt
    25861 caacttcaaa tgtcaattat cctaaaattt attggattaa gtcatagatt tccatcgcta
    25921 cgatatcgat attatcaaat tcgtattgct gatgagtatc tgtttcagtt aattcaaatg
    25981 tatcggtcgc tttatcataa gttactgtac acttctctac gccttctttt tcaaaacggc
    26041 gaacttgcag ttcattatct gctgactcga ccatagcctc cagtcgtttt atgattgcga
    26101 ctaattgtga atgtgtcatc ggaggtcctc cttttcttat ttctgttata ttgtatcaaa
    26161 agcatagcct acttgcattg attttctcta aaaaaactcg ttttttatga ttttttttct
    26221 ggtatttttc cttcaggcca ccaaagtttg atcaaagctt gggttccgtc attctcaaaa
    26281 cctttatctg ccaactcttc atatagtttc aatgcttggg tagttgctgg caatacaaga
    26341 tccatttttt ctgcttcttc taatgcaatc tttaaatctt tgataaaatg tttgacaaaa
    26401 aaaccaggtg tgtaatcttc ttttaaaata cgaggagaat aattgcttaa agaccagtta
    26461 gctgcacttc cacctgaaag cgtctcaatc actttcttta aatcaagtcc gtttttttgt
    26521 gcatagacaa gcatttccgt cattcctgtc atcgtacctg caatcatgat ctgattagcc
    26581 atttttgtat gctgaccttt cccagcagaa ccatgcaatg taaatgtcgt accaaattct
    26641 ttgaataaag gcagtacttg atcataaacg gcttcttctc caccgaccat gatcgtcagt
    26701 gtaccattct ttgctcctaa gtcaccaccg gataccggtg catctaacgc atctgcgcct
    26761 ttttcttttg ctgtttttgc aattttttct gccaggcttg gtgtacttgt agtcaaatca
    26821 actaaaatat gtcctgagat atctgcagaa aaaatccccg actgtccata gtagatttct
    26881 tctacatctt tggggtaacc taccattgta aagagaatat tactttgttc tgctaccgct
    26941 tttggtgtat ctgcccagat agctccttct gttactaaag gatcagcttt tgcttttgtc
    27001 cgattataga cagctacttc gtgtcctgct tctagtagat ggcgtgcgac agcacttccc
    27061 atgacgcctg ttccgataaa accaagtttc attttttcga cctcctaaaa atcaaaaatc
    27121 cttgcttcta tgctagtata cgctagaaac aaggattttt tcataaaaaa tgtttgaatt
    27181 ttatctttta aatgaattta attttatttt gattcgttca atcgagtctt cttcttcttt
    27241 tcttcgcatc tcttcttcat gataaacaac catgtcttga taaaattcga tcatagcttc
    27301 gccgaaatgt gtagatgaaa tatcataaag tttagcttct aaaacttttg gatctttagg
    27361 aacttcactg gaaatataat caataagtgc tggtgcaaag tcttcgtcgg tttcaaaagt
    27421 tttccctaat gaaggatgat cgaacaatcg gttcaaataa gcatttcctt ccacgacaca
    27481 aggtgttccg gctgccatcg cttctgtata agtaagccct tgtgtttctg aagtagaagc
    27541 actgacaaaa taatctgccg ctttataata aagtgctaca tcattgttgt ccacttctcc
    27601 tgtgaactgc acaaattctt ctaactgcag ttctgagatc aattcctcta actcttctac
    27661 ataaggtcct tttcctacga taactaatct ggcgttagga taagcggaga tgacctgagg
    27721 aaacccatta atcaaggctt ggatattttt ctcataagaa atcctgctta aagaaagaat
    27781 catcaaatgg ttttcctgaa gacctagtga ctcccttaat ttgctgatat cctgctgagt
    27841 gatatcagaa cgtttgaatt tttcaatgtc gataccagta ggaatcacgc gaagcggtgc
    27901 tattacacca tagctgcgta atgtatcaat aacacgttca cttggacaaa ctacacctgt
    27961 cgtatgattt gcaaataatc tagacaagta ttttacatgg gattgcctga tcacttttcc
    28021 tttaccgata taatgaaggt agtcttcata catcgtatgg taagtatgga tcagaggtat
    28081 tttcaacttc ttagctacca tcttcccaag tatccctgct ccgaattctg tatgggtatg
    28141 aataagatct agttctagtt ctttggcaac caaataagca taccacatgc ctctaacaac
    28201 aactcttcga tccttgaaag aaataaatgg tacacttggc attcgaatca catctttttc
    28261 caacttatcc gcattaggat cggtcgttgt aaaaatatag acttcatgcc catgtctttc
    28321 taattcttgt tttaatgttt tgatcgatgt agcaactccg ctgacttgcg gaaagtaggt
    28381 atcggtaaaa aagccgattt tcatgttttt cgcctccaaa ctagtccttg acctgattta
    28441 ctttttttaa tttgctagag actttttcat tcagtacact ttcgtataca tttttaagtt
    28501 cttcaccgat tttattgata cttcgctctt ttgctgtttg ataaccggct tgtgtcgtac
    28561 tcggtagttc ttgattggta atctgttgga tcagtcggat aaattcttcg tttgtcttcc
    28621 ccatatagca gttcttgcta tcttctaacc agccattata cactggaata tctcgaacaa
    28681 gtacgttttg tttgcttgct aaagcttcta aaacaacgat cccttctgtc tcttcataag
    28741 aagggaaaaa gaatagatct gcacctgaat acgcaccttc tatgatctct ccacgaatgt
    28801 aaccaggaaa caggacattt tcaggatgat cttcttttac aattttccgg atgttccgag
    28861 gaatcgagta catgggaaca tgaccaaacc aaataaatgt gtattcgggc atcttcttag
    28921 caatttctac gaaatcaatg attcctttac gttcgaaaaa caaaccgaca caaatgatta
    28981 ctttttgatc cggagacagt ttgaaatatt ctctgaactt ttgttctttc attggatcag
    29041 ggtgatattt ctctaagtcg atcccattgg aaatagcttg aatcggcaca cggataccat
    29101 agctttccaa caactgtttt gaataaggtg ttggcgtgat cagatagtcc gctttttggt
    29161 acaatcctac cagatatttt tttacgatag gagaaagctg gttcgatctg ataaaggaat
    29221 ttcggaaatc ttcctctgta gaatgcgcat gatagacaac tttttttcct tctcttctgg
    29281 ctttattgac catattatga ctattgattc cgtatgtatt gatgtgcagg atgtcataat
    29341 cttctttttc atctagtgta taagagatac cgacttccgt cagagcacgt ttttgatgat
    29401 caagcgcacg cccgattcca gattttgcaa gcatcttttc actttcaaaa tataataata
    29461 ccttcacctt acgtccccct tcacttatat agtataacat agcctacaaa ctgtcactca
    29521 aacttaagcc ctatttttgt ctattcttac tgacaaaaac gttttcttaa aaaagaacaa
    29581 aaaaactggc gtagctcttt tacaagccac accagctttt gatacgttgt ttattttaca
    29641 tattcatgaa caagttcaac gacttcttcc atcatatcgc attctttcaa tgcacgatca
    29701 gcaagttcag ccattttcgc tgtgtccaag cgtttcatta aactacgcgt tttaagaata
    29761 gatgtcgcac tcattgagaa ctcatctaga cccataccta ctagcaatgg aacagctgtt
    29821 tgatctccag ccatttctcc acacatacct gcccattttc cttcagcgtg tgctgcatca
    29881 attacatttt tgatcaaacg taaaattgat gggttatatg gttggtacaa gtaagaaacg
    29941 cgttcgttca tacggtctgc tgccattgtg tattgaatca aatcgttcgt acctacagag
    30001 aagaaatcta cttcttttgc aaacttgtct gctaagactg ctgctgctgg aatctcgatc
    30061 atgatgccga cttggatcgt atcagatact tccttgcctt cacttatcaa tttttgtttt
    30121 tcttcttcaa agatcgcttt tgctgcgcgg aattctttga gtgtagctac catagggaac
    30181 atgatacgta aattaccatg aacagatgca cgaagcaatg cacgcatttg tgtacggaac
    30241 atttcgtcgc cttgttcaga taaactgata cgcaatgcac gatatcctaa gaatggattc
    30301 atttcatgag gtaattgcag atatggtagt tctttatctc caccgatgtc cattgtacga
    30361 acaactacag gttttccttc cataccttct aatacagctt tgtaagcttc atattggtca
    30421 tcttctgttg ggaagtctgg agaatccata tacaggaatt cagtacggta cagaccaact
    30481 gcttctccac cattattatg gacaccaact agatcttttg gtgttccgat gtttgcagct
    30541 aattcaaaat gcttgccgtc agctgtgaca gtttctgcat tttttaattt ttcccattct
    30601 gctttttgtg ctgcgtaatc tgcacctgct ttttcaaatt cagctttttg ttcatctgta
    30661 ggatcgatga ttacatcgcc ttcgatcccg ttgacagcca aaatatcgcc ttctttgact
    30721 ttagcagtaa tttcttttgt cccaacgatt gctggaattt ctaaagaacg tgccatgata
    30781 gcagaatgtg aagtacgtcc accaatgtct gttacaaacg cttttacaaa attgcgatct
    30841 aattgtgctg tatcacttgg agtcaagtca tgtgcaacaa cgaccacttc ttcgttgatc
    30901 attgatggat ttggtaaagt aacgcctaat aagcgcgcta aaatacgttt agcaacgtca
    30961 cgaatatctg cagcacgctc ttgcatataa gcattatctt ccattgcttc gaacataccg
    31021 atatacatat ccgttacttc ttttagcgct gattcagcat ttacgctgtt gtctttaata
    31081 ttttgcttga tttgacctac catttctgga tctgaaagaa ccatcaaatg ggcatcaaat
    31141 acttgcgctt ctgcttcacc taagctttgc gctgcttttt cacgaatttg ctgcaattct
    31201 tcagtagatt tagctaatgc agcatccaaa cgagcttctt cagccgcagt atcttctact
    31261 gttgccttac tgaatgttaa atccggttga actagcaggt aagcttttgc aacggctaca
    31321 ccgtcactag cggcaatccc ttttagcatt tcaaccatta ttcagataag ccttctttct
    31381 tcattgtttc aacgattgct gccattgcat cagcttcgtc agcaccttct gcagtaatag
    31441 taacatcaga accttgacct acacctaaag acataacgcc catgattgat ttcaagttta
    31501 ctgatttacc tttatactct aagtttacat cagagttaaa tttgcttgct gtttgtacta
    31561 atagtgtagc tggacgagcg tggatcccag tttctgctac tacgtgaaat tctttctttt
    31621 ccatattaat cggtctcctt taagtgagtg ttgtttttat gtgagggttt tcttttttag
    31681 taattcagag aatcctaaca aatgccaccc tttcatctgt aaagattaac attttttttc
    31741 gttagataca acagttttca ttcaatttca gataaaagta ttcaaattat tccggattct
    31801 ttttcatcct tttcttcaca ttttataaca aacgtgttta tttccttttt cttgtcgctt
    31861 tctcttctcc tgacgtttat cattctttcc tttgaccctc tttgttttca tatgaaacga
    31921 attacttgct tcccttttta tttttagtat aataagagtc aaaggtcagg aatggtcaat
    31981 agagatttca ccttttctac ctcataaatc tcttaaaaaa ctaggggtta ttcttttacc
    32041 tcatgaaaaa cgagatgtaa aatatggatg tacccatttt tgtgaaagga cgtgaatgat
    32101 tcatgctttg tcaaaactgc ggcaagaatg aggcaacgat tcacttgtat gccactgtca
    32161 atggtcagcg gacacaactc gattactgtc agagctgtta tcaaaaaatc aaaaatcaac
    32221 aaaatggagg tctgactaat atggcccaaa atgatccatt tggatttggc agtttggacg
    32281 atcttttccg ttccatgtct cgccaaatgc aacagcaagg aaattatgag caaacaccac
    32341 caacacaatt tggcggaaac aacaacttca atggtggtca gccacctcaa ggcaatacag
    32401 aaggtttatt gggagaatac ggaatcaata tcacagaaca agcacgacaa ggtgatatcg
    32461 atcctgtgat cggacgcgat gacgaaatca aacgagtcat tgaaatttta aatcgccgaa
    32521 ccaagaacaa tcctgtcttg attggagaac caggtgttgg taaaacagca gttgttgaag
    32581 gtttagcaca aaaaatcgta gatggtgatg taccgcaaaa attaatggac aaagaagtca
    32641 ttcgtttaga tgtcgtatct ttagtccaag gtactggtat acgaggacaa tttgaagaac
    32701 gtatgcaaaa attgattgaa gagatccgtc aagcagaaaa tgtgatccta ttcatagatg
    32761 aagttcacga aatcgtcggt gctggttctg ctggtgatgg aaatatggat gctggtaata
    32821 ttttaaaacc agctttagct cgaggagaat tgcaaatggt tggtgctact accttaaatg
    32881 agtaccgcat catcgaaaaa gacgctgctt tagaacgtcg tatgcaacct gtacgggtag
    32941 atgaaccaac tgtcgaagaa acgatcagta ttttgaaagg tttgcaaaaa cgttatgaag
    33001 actatcatca tgtaaaatat actgatgagg ccatcgaagc agccgcaact ttatccaatc
    33061 gttacgtcca agatcgcttc ttgccggata aagccatcga tttgctagat gaaacaggtt
    33121 ctaagaaaaa cttgacgatc caaatcgttg atcctaaaac aatcgagaaa aaactgcaag
    33181 aagcagaaga acaaaaagtt ttagcttctc gagaagaaga tttcgaaaaa gcagcttatt
    33241 atcgcgatca gatcaataaa cttcaaaaaa tgaaagaacg tcagctcact gaagaggaaa
    33301 cacctgtgat taccgaaaaa gatatggaaa aaatcgttga acaacggaca ggtattccag
    33361 tgggtgaatt aaaagaaaaa gaacagacac aactgaaaaa cttagcagat gacttgaaag
    33421 ctcatgtcat cggacaagat aacgctgtag atcgagtagc gaaagcgatt cgccgaaacc
    33481 gtgttggatt aaacaaacag aatcgtccaa tcggctcctt cttatttgtt ggaccaactg
    33541 gtgtaggtaa aacagagctt gcgaaacaac ttgcctacga actattcggt tcacaagatt
    33601 caatgattcg tttcgatatg tctgaatata tggaaaaaca tagtgtctct aaattgattg
    33661 gttctcctcc aggttatgtc ggatacgaag aagctggtca attaacagaa aaagtacgga
    33721 gaaatcctta cagtcttgtc ttgttagatg aagtagaaaa agctcatcca gatgttttgc
    33781 atatgttctt gcaaatctta gatgatggtc gattgacaga tgcacaagga agaacggtca
    33841 gctttaaaga tacgatcatc attatgacaa gtaatgccgg aactggtaaa gtagaagcaa
    33901 acgttggttt tggtgcggca cgcgaaggtg ttactcgttc tgtattgaac caattaaaca
    33961 actactttac accagaattt ctgaaccgtt ttgacgggat catcgaattc agtgcattat
    34021 caaaagaaaa cttgatgaca atcgtcacac taatgctaga cgatgtcaac caaatgctgg
    34081 cagcacagca acttcacatc gaagttccta cgaatgtcaa agaaaaatta gttgacttag
    34141 gctatgatcc atctatgggt gctcgtcctc ttcgacgcac gatccaagaa caaatcgaag
    34201 atggtatcgc tgaattttat cttgatcacc cttctatcca tgagttgaaa gcaaaactgg
    34261 ataaagatgg aaaaatcatc gttacttcta aaccagaacg tttggctaaa gaatcagccg
    34321 aagaaacggc tgaataaatc cagttttata gcgtgagacg gtatttcttt gagaaatgcc
    34381 gtctcattct tttttcagaa aagtcaaaat actgttcatt ttataaaaaa gaaattataa
    34441 taagagaaac aagcaattaa aaatacataa aagaggtgag cgccatgaaa ttggtaaatg
    34501 taacaaacag ccattcccgt cttgtattaa accagcttga aaacactgat gcccatctag
    34561 tcaaggtcta cacagccgga aataccacta ttgtctacac tgaagcccct gaacataatg
    34621 aaattctgct gatcaatgac aaacgtaaaa tccagccgaa agaaatcgaa gatgctaaaa
    34681 attatttctt agataaaatc aaagacgccg tttaccacga ggatgaaatc aaagtaatcg
    34741 aattggcagg ccttgttgaa atctcgattc caaaacatga attaggcgct acattagccg
    34801 tgtaaacaaa ttttgaacat aataattaaa gagcgtggga caaaagtaaa gaacactttt
    34861 gtctcacgct ctaaacacgt ataaacggcg aaagcagaag caactccttc ggaaataagc
    34921 tgaaattcac gaaaattgct tttcaaattt ttgtgaattc cagcttattt cttggagtta
    34981 aacgcttctg tctcagcctc tttttctttc tagctttttg atttttctct tttcttttgt
    35041 acttttctct tttcattttc agttctacgc gtgtctttat ttttaacttt ttcctcttta
    35101 tggatgattg atcgtacttt ttgtgcaatt tgctcgtttt tgtcccagtc ttttacatct
    35161 aataatcgac ataatcgtaa catctcttct tttttctgtt tttttctttc acgtctttgc
    35221 cattctgttt ccatgtgtca cactctcctt tctttaatca tatgtacgca aaataatttt
    35281 tatatttttt tgattagaca tttctatgat tttaatatag taaaaagagc cgtcacggaa
    35341 aatccgtcac ggctctaaac aaaatatgag aggctgtttt tgtttggcta ttcttattac
    35401 ttgatgcagg gcagcttgtg tcaagacttc tttacatcaa actttttaat tttacattgg
    35461 gatatttatc cgcaaaccag cgttctgcaa attggttctc gaataagaac aacggttggt
    35521 cgaaacggtc acgagccaag atattgcgac ttgaactcat cttctcatcc aaatcttctg
    35581 gatcgatcca gcgagcgatt ttgtgtccca ttggagacat gattacttcg gcgttatact
    35641 catttaacat acgatattgg aatacttcga attgtagctg accaacagct ccaatgatat
    35701 attcttccgt tagatatgtt ttataaagct gaatcgctcc ttcttgaact aattgataga
    35761 ttcctttgtg gaaggatttt tgtttcatga cattttttgc agtcactttc ataaacagct
    35821 ctggagtaaa tgaagggagt tcttcataag caacttttag ttttccttcg aacaatgtat
    35881 ccccaatctg ataattgcct gtatcatata caccgatgat atcgcctgct actgcttttt
    35941 cgacgttttc tctcgaatct gccataaatt gtgtgacatt gcttaatttc agttttttat
    36001 ttgtacgttc caaccagaca tccattcctc gttcgaatgt tccagaacag attcggacaa
    36061 aagcgattcg gtcacgatgg gctggattca tatttgcttg gatcttgaat acgaaacctg
    36121 aaaattcttc ctcataagga cttaccatct gatcatcttg tgttttgtgt ccataaggag
    36181 ctggtgccaa ttcaacgaaa gtctctaaaa aagtctgtac accgaagtta gtcaatgcag
    36241 aaccaaaaaa tactggtgtc tgatcgccac gagcaatttt ttcttgatta aatgcatctc
    36301 cagcctcttt gattagttct acttcttcta agacttgttc atataaggaa ttttcagtta
    36361 gaggatgatt ttcgggaagc agtccatctt catccaattc tactaatcgt tcatcctgat
    36421 aattttccgg acgataaaac tctacacgat tatggtagat atcataaaga ccttctagcc
    36481 ctttacccat accgattggc caattcatcg gataagattc gatatctaat agctcttcta
    36541 attcttctaa caattccaat ggttcacgac catcacgatc tagtttgttg ataaaagtaa
    36601 atatcgggat gccacgtttt tttacaactt ggaataattt ctttgtctgt gcttcgatcc
    36661 cttttgcact atcgattacc atgaccgcac tatccacggc catcaaagta cgataagtat
    36721 cttcagaaaa atcttcatgt cctggtgtat ccaagatatt tactcgtttc ccttgataat
    36781 caaactgcat aacagaacta gtaacagaaa tcccacgttg tttctcgatt tccatccagt
    36841 ctgatttggc aaaattacct gtttttttgc cttttacggt cccggcttga cggatagccc
    36901 caccaaacaa tagtaattgt tctgtaatcg ttgttttccc agcatccgga tgggaaatga
    36961 tcgcaaaagt tctgcgattg tccacttgtt gctttaattt tggattattc ataacctaac
    37021 tccatttctt ccattcaatt atttatattt tctctaggca cagattgtcc gatctcttaa
    37081 agaaagacaa tttcatatag ggctgtgaca aaagccgtgt agcagtctct ttttccgagt
    37141 aaacggcgtt ctagagacag cctatcagca ataagcccac ccaagccaaa aatacgaaaa
    37201 gctgtttttg cttggctgct cttattactt aatgcaggat agctttttca caacctttgt
    37261 caactactac aactgaatca gtatagcatg gattcagcga atgaaaaagc caccaaacca
    37321 taagagtcaa atattttttt gtcagctgac taaaagaaaa gacgtgttgc ttgtttattc
    37381 aagcaacacg tctttcataa ccaagtttcc aattatcttc ttggctcgtc atcttcgaat
    37441 tcttttctga agtatcttcg ttcttcttca ggttccgctt ctgtttcttc cggatcatga
    37501 aaaatgacac ggattttaag gattcgagaa ccttccattt cttcagaaac cagcgtaata
    37561 ttatcgacat caaacgataa cttttcgcct tcatccggaa tcatgcctaa tgctgtaatc
    37621 aaataaccag ccatcgtatc tacatcactc atatgcagat cactgtcaaa agcttcattg
    37681 aactcatcaa tcagcatacg tccttggatg atatattcgt gttcatcgat tttttcataa
    37741 agattctcaa cttcatctga ttcatcatcg atttctccga cgatttcttc taaaaggtct
    37801 tctagtgttg ctaacccaac gacgccgcca tattcatcta ataaaatagc catctgattc
    37861 tgcgtctttt tcatttcata taacagatca tcaataaaga ccgtttcagg aacgaataaa
    37921 ggctcctgca tgattttctt gatatctaaa ttatcaaagc cgaatttatg ggcagctttt
    37981 agtaaattct ttgtatgaag gattccgact actttatctt tgtcttcgtt ataaacaggg
    38041 attcttgaat agttttcgga taaaacttca ttcacatttt cttccacagt gtcgttgata
    38101 tcaatcataa atgcatccgt tcgtgggacc atgacttctc gggcaacttt cgtatcaaga
    38161 gaaaaaaccc cttggagcat ttctaattct tcattattca atacgccttc gttttcaagc
    38221 atataacgca tttcatctct ggtcattttt gaatcttcat catcaaaagt catcggcgtg
    38281 atacgcgcca ataaacttgt ggaagcagaa agcagccaga cgaagggctt agctactaca
    38341 ccaatcaagc gtatcagccc tgaagtgaac tttgcgactt cttctgattt atttaaagca
    38401 atacgtttag ggtacaattc tccaaaaaca atcgatacat aggtcaaaat agccagcaca
    38461 atgatatttg caatattttt tgccgctgtg ccgccaccta ataccggagc taaccgttcc
    38521 gataaagtat tagctagtga agcaccagac aaaatgttga ccaaagtgat tcctacttgg
    38581 attgtcgata ggaaattatt tggattctgc aatattttta aaagcttttg agatttcaca
    38641 tctccttcat cagctttttg ctcgattcga ttcttattga tcgaaacaac agcaatttcg
    38701 gaagctgcta aaaaagcatt gatcaatgtc aaaacgatca ataataaaat ctgcgctaac
    38761 agcgactgac tctcagggtc agcattcata atcgcattct ctccttataa aattaatttt
    38821 tagtttacga tagaaaaaaa cgtggcacta tagccacgtt aaaatggtat cacaaagcaa
    38881 ttttctttgc aataaaaaca agtgtactaa aactacctac gaggtcgtag caattttctt
    38941 cttgttttca ttttgcttgt cttctttgac gattttgatt atataggaaa tgatcgtctt
    39001 gcagattgcg taaaaaggaa cacctaagaa gataccaagc aatccggcaa tatttccagc
    39061 tactagaaga acgataatga tcgttaatgg atggattttc agtgatttcc caattacatt
    39121 aggataaatg atattcccat ccaactgttg gacgattagc acaaccacac aacaaagtaa
    39181 tgcttttacc ggatcattga agactgttac tagaaatgca ggtgctagtc ctagataagg
    39241 tcctaaatat ggaattaggt ttgtcaatcc cgcaatgacc ccaaataaga aagcataatc
    39301 cacaccaatt accatatatc ctaaaaatgt gaaggtacca acgaataaac attcgattgc
    39361 ttgtccgcta atgtaattag ccaatgtttt attcagttgc cccaataact ccacaatttg
    39421 gtttcttctt ttttctggga aaaactgttg gatgtttggc actagttttt ctccgtcttt
    39481 caacatatag aacaagatga atggtgctgt aatgattact acggttgccg aagcgatcgt
    39541 tccaacgatc gaacctaaac tattggatac tccactaagg aattgctgaa tgattgtccc
    39601 gtaagaaatg tctaattgct caaaatattt attgatatct acttccttga acaaaggcaa
    39661 ttcggctacc tcttttaacc agctttctac ctgtttgatg aaatcaggca tattagatgc
    39721 caatgaggaa atttgctgta ctagacttgg gatgacacta agtaaaatcc aaataattgc
    39781 tgcaactaaa aggagcagca caattgcgac agcccatatt cttttgattt ttgctttcat
    39841 caacagcttg acaataggat tcaataaata gtaaagaaag cctgcaatca gtacaggtgc
    39901 aaataacgtg gaaaaaaatg tcccgatcgg ttcgaaaata aagtttattt ctgatgaaat
    39961 catgatcaat gcagctatga tcaataattc aagcgaccaa aacattagtt tagactgtct
    40021 aagtttttca aacaatagat ttcctccttt ctttcttact agtatatatt atattcgtta
    40081 aaaattcttt tattcttttt ttatttttga aaacttgcca tactttttat ttgttttatt
    40141 ttccagtata ctatacgaaa ggaaggtggc tagaccatga aagttgtaca aacaaaagat
    40201 acaatgagca atatttactt agatgctgta cggatcaggc atcaagtttt tgtagtcgaa
    40261 cagggtgtgc ctttgtctcg agaaatagac aaagatgaag cccattgtat ccacttcgtc
    40321 ctgtactcag ataaaaaaga accgcaagga actgtacgtc ttttgccttt agaaaacgga
    40381 aaaatgaaat tacagcggat ggcgattctt tctgaataca gacaccaagg gttaggaaaa
    40441 atattgattg aagaagcaga aaactttgct aagaatcaag gctataatac gattttatta
    40501 ggggcacagt ccacagctga aactttttac gaaaaactag gatatacagc ttacggcgat
    40561 ccttttgaag atgctggcat gcctcatatt tatatgaaaa agactttata aaaatttatt
    40621 tcgaaaaaag caaaaaacag caagcttttg agaaaaatct ctcactggct tactgttctt
    40681 ttttgtgttt acttacgcga caattgcttg taacggttat accaaatatc aatatagcct
    40741 tccgagaacg ggccatctcc attattgatc cagtcaacca gaatcttcac attttctttt
    40801 aggatgaagt caatatcgtt cgggtaattc atcattttgc tgtgcatctc atattcatcg
    40861 acatccaata gtcgtttctc gccgtcagga aataccttga tatccaagtc atagtcgata
    40921 tatttcaagg cctcatcgtc cagcaaaaaa ggtgaagcta gattacaata ataggaaacc
    40981 cccttttctc tgatcattgc tattacattg aaccagtatt ttttatgaaa ataaacaatc
    41041 gctggttcgc gcgttaccca tcggcgtcca tcagattcag tgactaatgt gtgatcattc
    41101 acgccgatca tagagtgttc gcttgttttt aataccatgg tatctcgcca cgttcgatgc
    41161 aatttgccgt cgtgcttgta actttggatc gtcacaaact ctccttcttt tggaactccc
    41221 atagcaaccc ttccttaagc agcattttgt gctttgtgtt tgggtgttca ttacaccgac
    41281 atcataatta ttatatcaat aaaaatgagc tttgcctaga aaggattcct attgtttcga
    41341 tttttctcta actgatctac cagtttcatt tggaccttag gaaaaacgac cgaatcaaat
    41401 gcatcaggct tcaaccactt cgaagttttg ttctcggtaa attcttgttc tgctccctcg
    41461 gttgcccgtc cgtaaaaaag gagaacatgc catttcagat gactaaaaat atgagtaact
    41521 tctcctaaat gtcgtgtctg ccaaacaaag agttcctgct tttcaaatgg gagattttgc
    41581 tcttcttctg ctactaggtc atcaaacaga tcgatttctg gctttgtttc ccattctttt
    41641 ttcaatcgct catactcctc ttgtgtcact tccatcattg gaaatgtcca catattcgcc
    41701 agcaattttt ggctatctct ttcttcaaaa taatacgctc cagaatgatt ttgaagagct
    41761 gcactgatat aataaacgtc ttttggcttt gctttttttg tttttacagg aaaactcgtt
    41821 tggattcctc gtttgttagc taaacaaaag gcttggatcg gacaagtctc acactttgga
    41881 gaagttggtg tacagatagc tgaacctaga tccatcattg cttggttgaa ttcacctgga
    41941 tgcttttcat caatgatttt ccgcatcgct tcatcaaaga ttttcctgct agaagctttt
    42001 gcgatgtctg cttcaatgca aaacaatctg ctgactactc gcatcacgtt gccgtcaact
    42061 gcaggttctg gaagtccaaa tgcgatactt gcaatcgcgc ctgtcgtata tggtcctatt
    42121 cccttcaatg agctaatttc ttcaggcgtt tgcggcattt ccccatcaaa ttctgacatg
    42181 atctgtttag cagcagcttg gatgttccgg gctcttgagt aataaccaag gccctcccat
    42241 gcttttaaaa gcttttcttc tggagcattt gctagctctt caattgtagg aaaccattcc
    42301 atgaaacgat aaaaataatc gatcactgtg tctactctgg tttgctgaag catgatctca
    42361 gagatccaga tacgataagg atcacgatta tagcgccaag gcaggtttct tttttcttgt
    42421 tcataccatt gaatgaactg atcttgaaat tcttttgttt ctttatctgt ccatttttcc
    42481 cattctttat tcactttcct cttccttttc cgtaatgaat cgctggatca tatccaaatc
    42541 aaatcctttt tgatataagc tttgctttac ttttagattt ctttttttag gttcaaacct
    42601 taaatttctt cgccatagtt tatctccttg tttgactaaa taatcatatt ctatttcttg
    42661 atctgcttct tgcggaagat cagctatcgc ttgttggatc acttcttgag aaaagccttt
    42721 cgtcatcaat gtttgttgga tttttctcaa taattctttt tggctttttc cgtgattttt
    42781 tccaaacgct ttttcggctg tctgatgtgc attttgaact tggtcttcaa atgtatattg
    42841 gctgagcgct tgttcaatga tttcaggttt caaacctttt tgctgcatct gctgcgctaa
    42901 tttctttggt cctttgtcac ttaagcgcat attcgtgcgc acataacttt ccccatagac
    42961 caaatcatcg acaaggtcca attcttttaa gcgggctacg attttatttc gatcttcttg
    43021 aaggatttcc ttttctttta agtatgttcg gatttctttt tccgatcgca actgataact
    43081 taagtaattc attgctaggt gaaaaccgaa atcagctccg ctactcttct tgatctcttg
    43141 gatagtttct tcgtctaatt cccgtccttt taataatcga tagcgtacta atacatcttc
    43201 agatacttgt aaagcttctc cttcagataa atctacgcga tagaaagggc ctttgccttt
    43261 actgattctc gtaacggtta acataaacat cctcctcgaa catatattct ctatcatacc
    43321 acagaaaatc cccgtaatca ggtattatat gttagaataa accacagaaa aaagaaaaag
    43381 ggagatactt atggcagaaa caattgtcaa aactggacaa acggttcctt tgaaaatcaa
    43441 gcgtttaggc ataaatggtg aaggaatcgg ttatttcaaa cggttgatca tatttgttcc
    43501 atatgcacta ccaaaagaag aagtactagt gaaaatcacg aaagcaactc ctcgctatgc
    43561 agaaggagaa ttaataaaag tcaaaaaaac aagcaaagat cgcgtagtgg caccatgtcc
    43621 tgtttactat gaatgcggtg gctgtcaatt acaacactta gcttatcaag ctcaattgga
    43681 ttttaaaaag gatctgcttt tgcaagcatt ggaaaaattc aaaccagcag gctttcgatc
    43741 ttatcaactt ttgccgacga tcgggatgga tgagccttgg cattatagaa acaaagcaca
    43801 atttcagtta cgaaaaaata agcagactca aaaaattgaa gctggtttat acgaagcaaa
    43861 ctctcatcag ttagtcccta taacagactg cttggttcaa gaacctcgaa cacaaaaagt
    43921 aatgaatact gttgttcaac tattgaataa atttgatgca cccatctatg atgaacggac
    43981 aaacagtgga atcttccgca caatcatggt tagaatcggt gttaaaactg gggagttaca
    44041 agttgttttt attactcgca gtaaaaaatt cccgcaaaaa aacgcaatga tccgtgagat
    44101 caatgaacga ctgcccgaag ttgtttcaat catgcaaaat gtccaggcac aaaaaacgtc
    44161 tctcgtgatg ggggatgaaa cgatccactt atggggaaaa gaagccattg aagaacaaat
    44221 caatgaagtg actttcgatc tttctcctcg tgccttcttt caactcaatc ctcagcagac
    44281 cgaattgctt tatggcgaag gaatcaaagc attagatgtc cagcctaatg aaacgatcgt
    44341 ggatgcttat tgcggagttg ggacgatcgg cttaagtgta gcaaaacaag ccaaagaagt
    44401 acggggaatg gataccgttc ctcaagcaat cgctgatgca aaaaaaaatg cggaaagatt
    44461 aggatatcac aacactcgat atgaagtcgg gacagcagag caagttctgc ctaaatggtt
    44521 gaatgaaggt tttcagcctg atggtatcat cgtagatcca ccacgtacgg gtttggataa
    44581 cgcattgatc caatcattat tgaaataccc tccaaaaaaa cttgtttata tctcctgtaa
    44641 tgtttctaca cttgccagag atctggttaa tttaagtaaa aagttcaaga ttgaatattt
    44701 acagtccgtc gacatgtttc ctcagactgc acgttgtgaa gttgtcgtga agatgacgag
    44761 actcgctgac taaatgaaag aggttgtgaa aaagtctgcc ctgtatcaag taataagaac
    44821 agccaaacaa aaatagctct tcatgtttta tgaatactgt acttgtgacc gaagagttaa
    44881 caggaggaca ctatttattt aaaaaaaggg ttgtgacata gtttttgtca cagccctttt
    44941 tgattattat tggatattca cgtctatcac ttgataaaat gcatttgtcg tatcgctgat
    45001 attccatact gctaaaatca cattatatcc ttttcgatcc tgcggaagtg tgatcgtttg
    45061 gttgactgtt tttggtggaa cagttgcttt gtcgtctatt tttgtgatca attcaaaatc
    45121 actaaatttc aaaggttgat taggattcca agttggtttg gtaatgtagt aatcccaagt
    45181 acttgtccga tgttgtgctg ttaaattcca agtaatattt aatgttcctg gattaaccat
    45241 gtttttatgc catctgttag atgtctgttc atctaaaggc tcaaagccgc tgactcctgc
    45301 actagcaatt tttccatcaa tgaatgtatt tttggtagct tcgatacttt gcggttccca
    45361 ttgtgctctt ccgacatttt gatttaagtt tcctgctgct gatgttccta ggtatgcacg
    45421 gcttcctgga gaagtaatat aaccatgcgc aaaacctgga atgctaaaac cgaacaaccc
    45481 taaactaact aacccaataa acaataacgt actaatcttt ttcatgtaga aacctccttc
    45541 atttgataac cacattgtaa acgctttatt gtattaacac aaacattatg cttttataat
    45601 tttatgttga agtaaaaaag gtgaaaaaag taagatgcag attataacag aagtagacga
    45661 gaaaagtaca aatagaaaac atgagaatca aatcatatga tctttttcaa aaacatcatt
    45721 catataaaca aatgttcaac tttttaataa caacaattat caattttttt cttacttcac
    45781 aaactaaata caggtcttgc tgtgagcctt catggtaaac taatattata gaaaggagtt
    45841 agtaaaatga agatgataaa agatattcgt ttttgggttt gtgttatagg aattgtcata
    45901 ttaggctttt tatcagggtt gcttagcgga aatcccggaa aatattacta ttctttgcaa
    45961 cttccaccat ttgcaccacc tagctggata tttgggccga tgtggacctt actgtatata
    46021 ttgatgggta tttctcttta tttgttactt aatcacaaca acaaaaaaca gcgaaacaat
    46081 cttgtcggtc tttttgtgat tcagttcatt tttaatttta tatggtctgc tctatttttt
    46141 aatttaagaa atattttcat tgcagcaatc gatattacac ttttagttat tttcttgtca
    46201 gtgcttatgt atcagttgtg gctgcatcat cgcctggcaa tgtggctcat gattccttat
    46261 tatttatggg tactattcgc aactctattg aattattcaa tttatttttt aaactaagcg
    46321 ctaaaaagag acgtcctgta atttaacaca tagaaaaagt gccacctaag ttagattttt
    46381 tgtctaattt aggtggcact ctttattaac caaactattt ttttctagta cccacttgtt
    46441 gttccatact cattattctg gtcataacca taaccatttt gttcctgtcc agcgtaagga
    46501 tcataacttt gagtatcttg acttggtgta tagtactgac ttgtatcttc tgtttgctga
    46561 taataggtat tcggatcttg gtactgatca tatgtgtttt ctgaatagga agaataatcg
    46621 gtgtaccctt cactattcga tccatcaccg tttgtcgaat cgccatcttc cgaatcatca
    46681 aagaacatca ttgaagcatt ctcatttttc aaattaggta atgtatcgct tgtttttata
    46741 tttaattgtt tcttcagttc attttggatc gaaagaagat cattttttcc taaaatttga
    46801 tagtagatat cattgatcat ttgtccttcg ccttgcaact ggtcttgttt gattgtttca
    46861 aacgccgggg tgtagttcgt cgctacatca agcatgtcat cccaatctaa gtccgtcgtc
    46921 acattgttct caactgcttt taaaattttt ctataattgc ttacgccatc taaacttaaa
    46981 actttattga cgattttcgt cactacttcc cgctgacgac gttgtcgacc gatatcgcct
    47041 tctggatctt cgtgtcgcat tcgagaatag gctaaacctt tttctccatt caatgtttgt
    47101 tcacctactg gtacatggac accatccaaa gtaaagtcaa ttttattatt cactttgatg
    47161 ccaccgaccg cattgatcaa atcttccatg ccatccaaat tgatcgttac ataatgatca
    47221 ataggaatat cgagcagttg ctcaattgaa tccatggcca tttcgacacc accaaatgcg
    47281 taggcatgat ttaatttatc taccgttcca taacctacga tattcgtata aatatctcgg
    47341 tccaaactga tgatcgttga ttttttttgt ttcggattaa ctgttactac catcatcgta
    47401 tcagaacgtc cttgttccgt tcttcctaat ccaccggtat ctaaacctaa tagcaaaacc
    47461 gaaaaaggtt ctttgtcatc aatgcttact ctctcagaac gtttggagga tattcgatta
    47521 gagtttttag aaattttgtt tactgtttgg ctcgcttctc ccataaatct gattccgtat
    47581 gctgataatc cggcaatcag caaaacgaat acccctaaca aggttaatag aactttttgc
    47641 catcgcttca taatacacct ctgtttcaca ttttctaaaa tattgtctca tataactgtt
    47701 caatcagcaa attcactttt taatcataag aaaactttaa aaaacatttt tgtgtaacga
    47761 ttattatttt ttaaaatttc tcaaaattct taactatcat accataccgt gaaaaagatc
    47821 gaaagaccga atacacgcag ttcgcaatcg ttttatcttt ttttatgtat tttttccaga
    47881 aaaagcgaac aacaaggtat tttccaaata atcgtgcagt aaaatgatcg cacatacctt
    47941 tcccatcttt ttaacagtct ttgcctaccg ttcagattat cattcgattt cacgacaatt
    48001 tcttcctatg actggtcctt ttgttaaacc catcttctat tcgttttatt tccagctcac
    48061 tgcatggctc ttaaaatgac tcgaactagt gattgcatta ccatcatctt ttaatggata
    48121 gatatgctcc tcttcaaagt aaaacgattt tcttttaaag taatagaatt gacatggtaa
    48181 tgagtatgta tactagtggt ttcacaaatg gtcttttatt caacatccaa aaactgaaat
    48241 ttctttaaaa tccattacta acgaagaaaa tgttccttgc ttgataatta gttaggacat
    48301 gtcaagtgaa caaatgcatt tacttagcca aaaaatctaa aaacttcata aatagacaaa
    48361 aagacacgac tctctaagaa gtcgtgtctt tattcaacaa attattataa tttagtcact
    48421 tcagcagctt gaggtccgcg tgcaccttca acaatcgtga attctacttc ttgaccttct
    48481 tctaggctct tgaagccgtc tccttgaatt gctgagaaat gaacaaatac gtcatctccg
    48541 ccgtctactg taataaaccc aaatcctttt tcattgttga accatttaac cgttccgtgt
    48601 tccataaatg tatatcctcc aaaaaagttc ttgcaagtaa ccttgcaaga acattatacc
    48661 caatttagaa aacgctagca agctttcgct cttttatttt ccaaattatt tttaagactg
    48721 atatgacgga ggaaatggtt attttgctgc ttcgaaacgt ttgtttactt catcccaatt
    48781 aataacattc cagaatgctg caatataatc tggtcggaca tttttatatt tcaaataata
    48841 agcatgttcc caaacgtcca aacctagaat tggtgtcttt ccttccatca atggagaatc
    48901 ttgatttgca gtagaggtaa tagctaattt tccattttcc attacaagcc aagcccatcc
    48961 agaaccaaat cgtccagcgg ctgctttttt gaattcttct ttaaaagaag aaaaatcacc
    49021 aaaagcttca ttaatcgctt cttttatttc tcctgtaggt tcgccaccag catttggtgc
    49081 catgatttcc cagaaaaatg aatggttagc atgtccgcca ccattgttac gtacagctgt
    49141 cttgatatct gttggaatag cgtccatatc agataataat tcttctattg ttttttcgcc
    49201 taattctggg tatttctcaa ttgctgaatt taaattcgtc acataagtat tgtgatgctt
    49261 atcatgatgc agatgcatcg tttcttcgtc aatataaggt tccaatgcgt catatgcata
    49321 aggtagatct ggtaatgtgt aagtcataaa aaaattcctc ctcaatgttt tcttaataat
    49381 gtctacatta caaagagtaa caaagagaag gaaattcttc aattgttatg cctagtcgtc
    49441 tttttcactt tgacctactt cttcttcaaa aacctcagtt tctttaaaaa taaacaactt
    49501 gctgaaaata tagttcgcaa ggataacaat aatttgagtg atgattttcg ccacatactc
    49561 attgctgttc ataacattga tcaacaatac cattgccccc atgtccaatc cgtaagaaag
    49621 gatacggtag aagaagaact taccgcattc aataagtgca tgtgtaaaat tcggtgattt
    49681 tgaatggaat acccaaagtt tgttcgttac aaaagcaaac aatacagaac aaaaccacga
    49741 aatagaattg gataaggcca tacttaaatc aaaatattgg cgtgcgagag caaaactaac
    49801 aaaatttaca atcgtagcca aaccaccaaa aaagagatag actagtatct cccaatatcc
    49861 ttttgcttct aaatatcctt ttaactgtcg atactgcttc atgagccaac ctaccttatt
    49921 aaaaattctt atttatcata ctctatattt caataacttt catctttatt taaaaaaatt
    49981 aatttttttt gatcctttgc ctttgtctct gcttggatcg tcacatgtgt aataccatat
    50041 tttaatttta ataaagaaat tatacgagga tatatctttt caatctcgct tagtagctga
    50101 tcttcaaaat caatatgtcc gtcgaaaata attatctttt cgctatactg ccaaatatgg
    50161 acatgatgaa catcctttac cccatcgatt gcttcaattt cttgttccat tttttcatag
    50221 tcgatagcag gtgcactttg tatcaaaata gcggcagctt ttttgatcac cattatcgct
    50281 tctatcaata tatatatcga aatgatcagt gtaataactg gatcgatcca gtagatatcg
    50341 aaaaaacgga tcaaaattgc tccgataatc acacttaccg aagacagtgt atcacttaac
    50401 aaatgcaaat aactagattt tatattcaaa ctttcatctg cttcttgtcg taataataat
    50461 actgagaaca aattcgcgag caatccaata actgctactg ttagcatcaa atgactattt
    50521 atcttttctg gtgaagtgaa ccgcttgaat gcttcaacgg ttaaaaacaa ggataatatg
    50581 atcaatatga atgagttgat gaaagcactc aatatttcta aacgctggta gccatacgta
    50641 cgttttttat ttgcttcttt tcgggccatt ttttgtgccc cgtaagaaaa aataattgcc
    50701 aatgtatcac taaggttatg gaaagcatct gaaacaagag acaaactccc tgacataatc
    50761 cctccaataa attctgataa agtgatcacc gcattcaaaa ccactactcc aaatagtttt
    50821 tttgatgatc tctgtggctg tgtaggcact attccttcct ccattttatt tatattggat
    50881 agtctttaga caagaataac atttttttga tatttcacca atcattcagc tgtttcctta
    50941 aagcacttgt atttcacttg atacttcgct agaattgcaa gtgatgacac tactagatga
    51001 ggagtactta tgacaacaaa acaattaatt atcagttcct ttatacgatt caaagaccta
    51061 aaggaggcga gaaatgtccc attttggaaa gccattgtct atcttttagt tttgagtata
    51121 attatggctt tgccaatctc ttttcaagtt tttcaagtct taaacaacat tcaattggat
    51181 gggcaaaaga ttgctactcg cattcctgat tttacaatcc aaaacgggca gcttcaaacc
    51241 gaagaaaaag aaggattcat ttaccaaaca aactccatta tcttcacatt tgatccagag
    51301 ggaaaacgaa cagaacagga catctctact gatttgatgg ggaattttgt tagtgtcggg
    51361 atgttaaaaa acaaacttat catagctctt cctaatacag gcacgacttc tgctttgttg
    51421 aacaataacc aattagaact tccctacacc aatgaatctt taaaaaactt aacaggtaag
    51481 cagctccgtt cttttttaag tgaagcatct ataccacttt ggataaaagt cctgacattt
    51541 atattttcta tttatcctag ttttctgaat ctgctgatca ctttgctatt taccaacatt
    51601 gctgcttttc tctatgcacg ctttcgacta acaaaagcta cttttcttga ttgtttaaaa
    51661 acattgatct attcaatttc attgcctact ataattgcaa caatcttgat ggtctttctt
    51721 ccttcttttg acactagcgc cttcattgct tttgcaggaa tctttatttt tgctcaagct
    51781 gtcaaaggat gggcaaaaat atcgatcaat taagaaataa agacaactcg ttatttctac
    51841 ttcaatagac ccttttagag gttgtgacat ttttttgtca cagccccttt tttatttgaa
    51901 aaatatttct ttctcaaaaa acaagcaagg cgcttcaaag ttcttcttgt atgcgctaca
    51961 cttagagtaa agaaaggcgg gaaattaact atgtcagaaa gaatcattta tgcagatcgt
    52021 ccatttcgtg atgaatttat cgaagaaatc catactatag cgcctggtta tatctttaaa
    52081 acagaattac aaccagagga tctacaaaat gtagagatca gtttgggctg gaactcagac
    52141 taccaagaaa aactattagc ctcttctacc ttgaaatggg tccaatctat ctcagctggt
    52201 gttgatcagc taccccttga gactttttca aagaaacata ttttactttc aaatggtagt
    52261 ggcatccaca gtgaatcgat tacggagcat gtcttaggaa tcatccttgg gtattctcgt
    52321 ggtctttttc aagcacaaaa ggcacagagt gacatgaaat ggttaggttc atcggtccat
    52381 taccaatcta tccaagggaa aaaaatacta atcattggaa ctggccatat tggaaaaatg
    52441 attgcaaaaa aatgcaaagc attagacatg aactgctatg gaatcaatac atccggtcat
    52501 ccagcagaag gaatggaaaa gactttttct ttaaatcaac taaaggaagt tcttcctgaa
    52561 gtagatttcg tagtcaatat cttacctcta acggaggaaa caactgggct ctttgatcag
    52621 catatgtttg aacactttga tccaaaatct gtattcatca atgttggccg tggtgcttct
    52681 gttaagacac aagatctggt gcaggcttta aataaccagc aactttcctt tgcagcatta
    52741 gacgtttttg aggaagagcc tcttccacaa gatcatcctc tttggaaaat ggacaatgta
    52801 ctgattactt cccacattgc aggtttgaca cctgattttc aaaagaaatt aatggctatt
    52861 tttttaacca atctgaaaag ctactttgcc acccatgagc ttcaaaccaa tcaagtaaaa
    52921 ttgtctgcag gatattaata gctgaaaaca atattttcaa aagaaaaaag agaaggtgac
    52981 aaaaattgtg tcaccctctc tttttttatt gttttttaaa gtgataggtt ggctcctcca
    53041 ggttgggatc ataatcaaca agtaaatcat atcctttaaa gaaccattca tctgcttcct
    53101 cgataaaaaa aagtgtccca tcaatttcca ctttctttac aggatgttct ggctgttcaa
    53161 ctgacattcc aatcgaaaaa ccatcatgaa cctctgtttt gccgtagact tttccaaaaa
    53221 aacgtattcc gtaagtttct ggcagatcaa tttctgagtc aaaccacttt tgtgcttttg
    53281 gcgttaccgt taatttcatc ccaacaacct actttctctt ttctttctat tgattcatct
    53341 tatcgtctag aatatccaca tcgcctgtct ctccaataac cagtagatta tcattttcac
    53401 gaacatattc atctgctgca ggagaagcga taaccgtttg atctactctt cgtatggcga
    53461 ctactgttaa gtcaaaacgt tgcctgaaat ttaattcagc taatgttttg ttgaaaaatt
    53521 taggattgga gactcggatt tctgctaaag aatatttatc tgacaactct aggtaatcta
    53581 aaatattctt tgacactaaa ttatgcgcaa tccttattcc catgtctcgc tcgggatgga
    53641 cgacgcgatc agctccgatc ttttcaagta ctctggcatg atactcattt tgggcttttg
    53701 ctaaaatatt tggtacgccc atttccttta ccatcagagt aactaagata ctggcttgaa
    53761 tatcttctcc aatagcgaca attacatgat cgaaatttct tatgcctaat gatcgaagtg
    53821 tcatttcatc ctgtgcattt gccacaacag catgagtggc tatattcata tattcattga
    53881 cccgatcttc attactatca atagccagta cttcttgacc agcttcgatc agtgttcggc
    53941 agatacttcc gccaaatcgt ccaagaccta caattgcaaa attttgtttc accgttttcc
    54001 tcctttagta tcttcttttc tcagtataac aaagccttta caaaaacaaa agcaagcatc
    54061 attattgtaa aaaagccaag aaaaataata gttattttct cagcttttga ttatcctctt
    54121 tatcatcgtt tttatttcac caaaccatgt ttgaatgcat agatagcggc ttgtgtacgg
    54181 tcttccactt ctagcttagc caatatattg gaaacatgtg tttttactgt tttcagtgta
    54241 ataaacaatt cgtccgctat ttcctgatta ctttttcctt cagaaatcag cattaaaatt
    54301 tcattttccc gattcgttag ttcttcatgt aatacaggct catttcgccg actcattttt
    54361 tccatcattt ttgttgtcac ttctggttct aatactcgct cgccacgttg cgttgccctt
    54421 atagcatcag caatttcatg tgcggtagag gtcttcaaca aataccctgc tgcacctgct
    54481 tcaatggcag gataaacttt ttcgtcatca ataaaactgg ttacgataat gattttagct
    54541 tctggccaat cttttaagat tgcttttgtt gattcgatac catccatttc ttccatgact
    54601 aagtccatta aaatgacgtc cggtcgaagt gtcatcgcct tctcatagcc ttgtcgtcca
    54661 ttttcagctt ctccaattac ttcaatgtct tcttgaatag ataaataaaa agagacgcct
    54721 aagcgcacca tttcatggtc atctactaat aaaactttta tcatccttat ctatgcctcc
    54781 ttcatcaaag ggaccttgat ttctacactt gtaccttgac ctttaaaact aatgattttt
    54841 actgttccac caataccagc tactcgttct ttgatattgt tcaatccata acttcccgtt
    54901 ttcgtttcat tcatattaaa ccctgttccg tcgtcaataa tacgtaacaa aagattattg
    54961 tctattttgt gcaaatatac ctctaattca ttggctttag catgtcttaa tgtatttgat
    55021 aacaattctt gaacgattcg gaacaagtga tcctcaatgg aactagatag ttttacatct
    55081 tctacatccc atttcagcga aatctggatt ttattttgca attccttcaa taactgctcg
    55141 ataccttgct ttaaactttt ctcttctaaa ttgactggac gtagatgaag aagcagcgca
    55201 cgcatctcag actgggaagc gttgatgatc tctgctacca ttttcaactg cttgcgaaac
    55261 atttctggtg tctcgctttt ttctgcttgc tccgtcaatg ccgacatcat catcattgct
    55321 gcaaacaatt gttgcgaaac tgaatcatgc agctcacggg ctaatcgatg tctttctaat
    55381 tctaaaattt cttctttggt ttgtccatct acatattggg gacggctcgt tacaatttgt
    55441 aattcactag atacttcaat cattttttct tttatcttag tgatttcctt atcaatatct
    55501 ttgatgtata aatcgtccga tgcacttggg atcggaagaa gcaacaattt ggattcataa
    55561 ttgccagaag aaagtgcacg cagcttttct tcgattttcc cgtattttgt cttttgaata
    55621 agtgataata atagaaagac aattaatcct acacctaagg aaatggctaa caaatggaag
    55681 ataagcggaa catataataa acgtgcacgc agtaattctc cccaccaatg actttgattg
    55741 ctggcataaa aataagtgaa aagtgaaaat agaataataa ggaaagccgc aatccccgaa
    55801 taaacagcta gcatcgctct ggatattttt cccatcatat tcgtatcacc tcgacatctc
    55861 caatcaaggt attagtaata atcttcaatc tacgagggtt ttcatcataa tcactgctgt
    55921 agattttgat ttgttcattt ttcaaagaaa attgctcttc ttcaaacaag acatttccta
    55981 ctaatgtcgc atgctctaat cggatggcta cgcccaaagg tactaagatc cgtgttctgc
    56041 ctatcccttt tcttacaatc acaatattat catcttttgg caaaagcgta ttgcccaaat
    56101 ctatgatagt atcaccagaa atgacggcga tgttgatatc gtcccattca tagacgtcgt
    56161 ttccaatacg ttggttaccg aataattgct gtcttttccg ctcattatta tgtgttttta
    56221 attgctctgt ttggatcatc atgatctgtt tctttcgcca aaaagcattt ttggttaaat
    56281 ctatccctga aatctctaca cctttcagac caataaataa aacggcaaat acagccatca
    56341 tccataaagc aggactgttg actaagctaa aaaaaatgac caaacttcct aatatcaatt
    56401 gaaaattttg aaatttagta cgaggatgtt tgcgcatagc tagatatata ttgaaaatac
    56461 cgaatatcac taaaagcaaa agtccagtat tgtttacgat ttgccaaaca gcaaataaca
    56521 gcagtagtgc ttcaactacc acaaaaaaac gccaagaact attcatcgct ctttctccct
    56581 cctgacacat tctcatttca tcatacctat ttttttaact gttggctata ggactttaga
    56641 tgtaagatcg tttgttgaaa tctaaaatac acaaagagaa aaagatctag agtgtatcat
    56701 cagtaagatg aactctctag atctttcagt cagactacgc ttgttctact ttgacgattt
    56761 taactaacat atcgccacct ggagtagcaa tagttacttc atcattttta cgtttgccaa
    56821 tcaatgcttg cgcaatagga gaatcattgg aaattttgcc agaaaacgga tctgcttcag
    56881 cgcttccgac aatcgtgtac tcttcttctt ctccatctgg tagttcgatg aatgtaactg
    56941 ttttaccaat tgatacctca tctgcatcta caccgtcgtt atcgatgatt tgagcaaaac
    57001 gaatcatatt ttcaattgtt gtgattcttc cttcaacaaa tgcttgttca tctttcgctg
    57061 attcatattc agagttttcg gaaagatctc cgaaaccgcg ggcaattttg attcgttcaa
    57121 tgatttctcc gcgtttgact gtttttagtt cttctaattc tttttctaat ttttctttac
    57181 cttctagagt cattggataa actttctcta ccatgtgtaa cgtctccttt tttcgataaa
    57241 ataccgcaaa aggtaatctt ttgaggaata tagtccaaaa aagattacca cgcttttctt
    57301 caaatgtaaa tgtttttcta aaaatgatca atgtctagag cctgtttttc taagaattat
    57361 ttacatattt ttccactaat tccatatgtt cttcataagt tttagcgaaa taaacatttc
    57421 cagtgctcgt atctgctacg aaataataat agtcattttc tgctggttct aatactgcct
    57481 tgattgcctc ttcgcttgga ttgtcaaaag gtccaggtcc atagccggta ttggtataca
    57541 aattatatgg tgaatctaca gctgtatctt catacgtcac taattctttg tgttcaccta
    57601 atgcgtataa aacagagata tctgactgaa gtggcatatt tgctttgatt cggttaaaga
    57661 agacttgtgc aatgttttta cgatcatttt cttttacgcc ttctttttca actagagaag
    57721 ctagagttaa aacttcttgt acagtcaaat ttttctgctt gatagctgaa taatagtttt
    57781 gcatgaccgt attcgtcttg ttcaccattt caatcactag atccttaagc gaagtactcg
    57841 tgtaataatc atatgtggct gggaataagt aaccttccaa acggtatttt gtgttctcag
    57901 ctttagatgc actttccaac agttctggga atttttggtg caactcgtta aagaaagtct
    57961 catcattcac taaatctaaa aattctttct tgtctttacc agttaccttc gctacccgtt
    58021 cagcaatctg atcgatatcg tacccttatg gaatggcaat tttcccatct gcaacttttg
    58081 ttggctcaga agtaccgcct tcttgcaact gtttgccaat ctcgtcaaga gtcatattag
    58141 gcgctaactg ataatagcca gcttgaaagc cagttaaatt tttaaatttt gtataataat
    58201 tgaaaacaat cccgctttta ataatattgt ccttctccaa aatctcacca atctgcttgt
    58261 tagaagagcc actcgggatc tcgacttgga ctaattggtc atctgattta tctaaaggct
    58321 tcaacccgct atctacataa cgatacacgg taaatccaag aaatccgcca ataatcaata
    58381 atgtaagagc aatcactaaa atgatcttcc tcacaatctt atcttctttt ttacgcagat
    58441 ttctccgctt gtcgattata tctgctgtag ctgccttact ggcttctttt ttatctttac
    58501 ttgggtgttg tttgtttcct gacaaaacaa ctcctcctta ctatcaagtt cgtaacttta
    58561 ttcattatac atgatatttg aattggcgtg aatgatttta tttaaatatt ctatcaaaaa
    58621 tgtaagtagt aaatccatta ctataagatt aaaataaatg ttatcaagat acaagctatt
    58681 ttagctttat tctttctgta aaaaagaaag gagactaaat aaactattat gaaaaaagga
    58741 aaacatgcta aaaaaagaaa atattcattt ttaatgatcg ttgtcgtgtt gtttagcctt
    58801 agtgcgttct ctacaggaac tattcttgga tggcaatttt acaataatga acactctcag
    58861 atagttgccc atgctcaatc agctcaaaaa aagttgatac tgactaccaa tgaacaacag
    58921 ctcgttgaaa aaatcgatca actattaaga aaaaatgatt atattggctc aatttacgta
    58981 aagaaaaata atcgcatcat catggaaaaa ggctatggct atgcgaataa actcacgcaa
    59041 caaccaaatg atccttctct ttattatcag attggttcgg ttcaaaaagc attgactact
    59101 cttttgattt taaaacaagt cgagcgtggg cacctttctt tagatactaa gctggctcaa
    59161 ttctatccac aaattgctgg cagccagcaa attactatcc gtgacttgct gtatatgcgc
    59221 tcaggcttgc accgaactgc ttctccaacc ataccgatga ctgatgaaga agtcgttcaa
    59281 tttgcgattc agcacttaaa atttacagat tatcagacct ctcattatga ttcattgaac
    59341 tttaccatat tgactggaat tttgatcaaa ttaacaaatc aaccgtatga aaaattattg
    59401 accgatgata tcatcgaacc tttaggatta cagcatacaa aattttatga ccaagtcaaa
    59461 aattcatcca atcatgcact atcctatcaa atgtctaaag aggatgatta ctttaaacca
    59521 ctgacagaat ctgaaacaga gatccataac gaattaggga ctggtaatat cagtatgtcc
    59581 gtctatgatt taaatacgct gtttacacaa gttttatctg gaaaactagt ttccaaagac
    59641 ttactcttct cattatggcg tgaaaatgcg aatggacatc catatagtgg tggggtatat
    59701 agcggagata attatatcct gtcgcaagga aatatcgact cttttgatac atctgctata
    59761 tttagcaaag attcacagga tgctatcatc atggaaagca atataaaagc tgacaaaact
    59821 atcaaactgc ctactgctga tctaagaaac caaatctatg acctgatgga aggaactact
    59881 aagttggcaa atagctgata tgatgaaaag atagcaaata ctacttcttt gaatagcatt
    59941 tgcttaaaaa aagtactcga ctaaacgtag gaaagagtgt gggacaaatc taaaaatcaa
    60001 tttttgctac agactttaat tccaaataaa cagaacagaa agaggtgttc ttctttctgt
    60061 tctgtccaaa ttattctaag atttctcttt accaacatta tttgacaaag ggcctattaa
    60121 atctaaaata gtatctttag attgctaaaa tatgtgctag caaatcattc atggcttgtt
    60181 cttattttta attttatgca ataaaaaaga agaacaatta gcgtgattat agaaataaat
    60241 aatgagattt tagaaaaaaa tgtgtatgaa tacctgattg ttactttatt tattccactt
    60301 tcacttttta ctgtaacaaa aggacctcct tgttttagta ctgtagcatt ttttgaatta
    60361 acagtaaccg ttaatccttt ataccggaat acaggtaaaa ctattgtttt gccttttgaa
    60421 gatttaaacg taaatgtaat ttcatcttta tttggagaaa agctactata aataacttga
    60481 ccatcttctg taacttgatg gtttttcaaa agcaattgat cttttttata gcctataggt
    60541 acataatcaa aattctcaaa ttcttcaagt ttattttcca tttgttcatt agaataagtt
    60601 ccttgaaaat tcatttcttt caccatgtta actactgatg aataatttaa aattgaaata
    60661 gctaatatta ataatagtat aaaatttctt ctccttgtat aagaaaattt ttccaactgt
    60721 ggagaaataa atagagatac tgaaaaagat atgaacaatg ttgaaaatat cataaaacgc
    60781 caaggagctt gaataatatt taaaggagta ttttgtaagg caaaccatgg aaatattttt
    60841 gtacaaagta gaatagatat tatacccatt atataagtga ttttagataa gattcctaat
    60901 tttttaaagt taaatgttag tataattaaa caaataagca aagttaagcc aataccaaat
    60961 gatagtaatt ctgaatctat acttccaatc aaaaactctt tacccagata aattgctctt
    61021 ttttgtaata tatccacata aggtctattc agatcttgat acaatgtctg ctcaatcata
    61081 ggacctataa acgctagtga aagaagtaaa gtaactatag cagcttttat taatttaata
    61141 attaagaaga tttctatttt ctttttccga taaaattgaa taattaaagc aattataatc
    61201 attaccatag tcatagctac agaaagaaca tgagtgtaaa ttaataaagt catgctaatc
    61261 gccaacataa cccaagattc tttttttgag tcgtaaagct ttataaaccc gagtaaaata
    61321 agaggaagta ttgacattgc gagtaattcc cccattgccc ctcgaagaaa tatttctaca
    61381 ctcctaaaag aagatgttgt atatataata gcgaaaaagg agctagtaac atgttttttg
    61441 gtaatttcat acattacata atgacatata aatagagtaa tgagcgtaac aatataaaga
    61501 aaaaggttat agcctattgc taaattagta aacttgatca ataaaaataa aggatataga
    61561 gttaaccatg ggtaaaaatt atttacttgc atgccatatg atctaaacgt ttcaaaatta
    61621 ataggggagc taaaaataga ttctaaactt aacgcacgat taatgtgaaa tgccgtatca
    61681 taaaagccaa atatttccat gtttttaaat gctggaaata aatataataa actaacaaat
    61741 gcataaacta taaatatttt tacagaaaaa atttttttca aattcatata ccacc
//
LOCUS       DAIGSZ010000006        61446 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.006, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000006 DAIGSZ010000000
VERSION     DAIGSZ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61446
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.006"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..562)
                     /locus_tag="NOB31_000406"
     CDS             complement(<1..562)
                     /locus_tag="NOB31_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HCI0972649.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(749..1399)
                     /locus_tag="NOB31_000407"
     CDS             complement(749..1399)
                     /locus_tag="NOB31_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972650.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            complement(1942..2877)
                     /gene="whiA"
                     /locus_tag="NOB31_000408"
     CDS             complement(1942..2877)
                     /gene="whiA"
                     /locus_tag="NOB31_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HCI0972651.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(2911..3909)
                     /locus_tag="NOB31_000409"
     CDS             complement(2911..3909)
                     /locus_tag="NOB31_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HCI0972652.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(3906..4790)
                     /gene="rapZ"
                     /locus_tag="NOB31_000410"
     CDS             complement(3906..4790)
                     /gene="rapZ"
                     /locus_tag="NOB31_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HCI0972653.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(4925..5656)
                     /locus_tag="NOB31_000411"
     CDS             complement(4925..5656)
                     /locus_tag="NOB31_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HCI0972654.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            complement(5660..6925)
                     /locus_tag="NOB31_000412"
     CDS             complement(5660..6925)
                     /locus_tag="NOB31_000412"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HCI0972655.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(7188..10004)
                     /gene="uvrA"
                     /locus_tag="NOB31_000413"
     CDS             complement(7188..10004)
                     /gene="uvrA"
                     /locus_tag="NOB31_000413"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCI0972656.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(10014..12008)
                     /gene="uvrB"
                     /locus_tag="NOB31_000414"
     CDS             complement(10014..12008)
                     /gene="uvrB"
                     /locus_tag="NOB31_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HCI0972657.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            12267..13769
                     /locus_tag="NOB31_000415"
     CDS             12267..13769
                     /locus_tag="NOB31_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HCI0972658.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            13771..14508
                     /locus_tag="NOB31_000416"
     CDS             13771..14508
                     /locus_tag="NOB31_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI0972659.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(14553..14726)
                     /locus_tag="NOB31_000417"
     CDS             complement(14553..14726)
                     /locus_tag="NOB31_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972660.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            14702..15367
                     /locus_tag="NOB31_000418"
     CDS             14702..15367
                     /locus_tag="NOB31_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0972661.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            complement(15449..16615)
                     /gene="dnaJ"
                     /locus_tag="NOB31_000419"
     CDS             complement(15449..16615)
                     /gene="dnaJ"
                     /locus_tag="NOB31_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HCI0972662.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(16766..18595)
                     /gene="dnaK"
                     /locus_tag="NOB31_000420"
     CDS             complement(16766..18595)
                     /gene="dnaK"
                     /locus_tag="NOB31_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HCI0972663.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(18646..19209)
                     /gene="grpE"
                     /locus_tag="NOB31_000421"
     CDS             complement(18646..19209)
                     /gene="grpE"
                     /locus_tag="NOB31_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HCI0972664.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(19303..20346)
                     /gene="hrcA"
                     /locus_tag="NOB31_000422"
     CDS             complement(19303..20346)
                     /gene="hrcA"
                     /locus_tag="NOB31_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HCI0972665.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(20580..21746)
                     /locus_tag="NOB31_000423"
     CDS             complement(20580..21746)
                     /locus_tag="NOB31_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HCI0972666.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(21762..21989)
                     /locus_tag="NOB31_000424"
     CDS             complement(21762..21989)
                     /locus_tag="NOB31_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HCI0972667.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            22473..23063
                     /locus_tag="NOB31_000425"
     CDS             22473..23063
                     /locus_tag="NOB31_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HCI0972668.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            23253..23966
                     /locus_tag="NOB31_000426"
     CDS             23253..23966
                     /locus_tag="NOB31_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972669.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(24081..25091)
                     /locus_tag="NOB31_000427"
     CDS             complement(24081..25091)
                     /locus_tag="NOB31_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HCI0972670.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(25128..25610)
                     /locus_tag="NOB31_000428"
     CDS             complement(25128..25610)
                     /locus_tag="NOB31_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HCI0972671.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            25760..26128
                     /locus_tag="NOB31_000429"
     CDS             25760..26128
                     /locus_tag="NOB31_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HCI0972672.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            26593..27045
                     /locus_tag="NOB31_000430"
     CDS             26593..27045
                     /locus_tag="NOB31_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0972673.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(27169..28020)
                     /locus_tag="NOB31_000431"
     CDS             complement(27169..28020)
                     /locus_tag="NOB31_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HCI0972674.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(28033..28818)
                     /locus_tag="NOB31_000432"
     CDS             complement(28033..28818)
                     /locus_tag="NOB31_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0972675.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            complement(29170..30111)
                     /gene="ribF"
                     /locus_tag="NOB31_000433"
     CDS             complement(29170..30111)
                     /gene="ribF"
                     /locus_tag="NOB31_000433"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HCI0972676.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(30115..31038)
                     /gene="truB"
                     /locus_tag="NOB31_000434"
     CDS             complement(30115..31038)
                     /gene="truB"
                     /locus_tag="NOB31_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HCI0972677.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(31406..33768)
                     /locus_tag="NOB31_000435"
                     /pseudo
     CDS             complement(31406..33768)
                     /locus_tag="NOB31_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            34216..34389
                     /locus_tag="NOB31_000436"
     CDS             34216..34389
                     /locus_tag="NOB31_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0972678.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(34546..34893)
                     /gene="rbfA"
                     /locus_tag="NOB31_000437"
     CDS             complement(34546..34893)
                     /gene="rbfA"
                     /locus_tag="NOB31_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HCI0972679.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(34920..37226)
                     /gene="infB"
                     /locus_tag="NOB31_000438"
     CDS             complement(34920..37226)
                     /gene="infB"
                     /locus_tag="NOB31_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HCI0972680.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(37239..37550)
                     /locus_tag="NOB31_000439"
     CDS             complement(37239..37550)
                     /locus_tag="NOB31_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HCI0972681.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(37547..37840)
                     /locus_tag="NOB31_000440"
     CDS             complement(37547..37840)
                     /locus_tag="NOB31_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HCI0972682.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(37862..39037)
                     /gene="nusA"
                     /locus_tag="NOB31_000441"
     CDS             complement(37862..39037)
                     /gene="nusA"
                     /locus_tag="NOB31_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HCI0972683.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(39060..39533)
                     /gene="rimP"
                     /locus_tag="NOB31_000442"
     CDS             complement(39060..39533)
                     /gene="rimP"
                     /locus_tag="NOB31_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HCI0972684.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(39678..44036)
                     /locus_tag="NOB31_000443"
     CDS             complement(39678..44036)
                     /locus_tag="NOB31_000443"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HCI0972685.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(44248..45957)
                     /locus_tag="NOB31_000444"
     CDS             complement(44248..45957)
                     /locus_tag="NOB31_000444"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HCI0972686.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(46025..47293)
                     /gene="rseP"
                     /locus_tag="NOB31_000445"
     CDS             complement(46025..47293)
                     /gene="rseP"
                     /locus_tag="NOB31_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HCI0972687.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(47454..48254)
                     /locus_tag="NOB31_000446"
     CDS             complement(47454..48254)
                     /locus_tag="NOB31_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HCI0972688.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(48251..49063)
                     /locus_tag="NOB31_000447"
     CDS             complement(48251..49063)
                     /locus_tag="NOB31_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HCI0972689.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(49258..49815)
                     /gene="frr"
                     /locus_tag="NOB31_000448"
     CDS             complement(49258..49815)
                     /gene="frr"
                     /locus_tag="NOB31_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HCI0972690.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(49818..50540)
                     /locus_tag="NOB31_000449"
     CDS             complement(49818..50540)
                     /locus_tag="NOB31_000449"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HCI0972691.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(50676..51557)
                     /locus_tag="NOB31_000450"
     CDS             complement(50676..51557)
                     /locus_tag="NOB31_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HCI0972692.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(51656..52438)
                     /gene="rpsB"
                     /locus_tag="NOB31_000451"
     CDS             complement(51656..52438)
                     /gene="rpsB"
                     /locus_tag="NOB31_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HCI0972693.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            52797..53276
                     /locus_tag="NOB31_000452"
     CDS             52797..53276
                     /locus_tag="NOB31_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HCI0972694.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            53493..54584
                     /gene="phnW"
                     /locus_tag="NOB31_000453"
     CDS             53493..54584
                     /gene="phnW"
                     /locus_tag="NOB31_000453"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HCI0972695.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            54577..54705
                     /locus_tag="NOB31_000454"
     CDS             54577..54705
                     /locus_tag="NOB31_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCI0972696.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            54709..55254
                     /locus_tag="NOB31_000455"
     CDS             54709..55254
                     /locus_tag="NOB31_000455"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCI0972697.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(55708..57399)
                     /locus_tag="NOB31_000456"
     CDS             complement(55708..57399)
                     /locus_tag="NOB31_000456"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HCI0972698.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(57819..58766)
                     /gene="arcC"
                     /locus_tag="NOB31_000457"
     CDS             complement(57819..58766)
                     /gene="arcC"
                     /locus_tag="NOB31_000457"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HCI0972699.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(58881..59900)
                     /gene="argF"
                     /locus_tag="NOB31_000458"
     CDS             complement(58881..59900)
                     /gene="argF"
                     /locus_tag="NOB31_000458"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HCI0972700.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(59991..61220)
                     /gene="arcA"
                     /locus_tag="NOB31_000459"
     CDS             complement(59991..61220)
                     /gene="arcA"
                     /locus_tag="NOB31_000459"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HCI0972701.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT        17090 a        13110 c        10628 g        20618 t
ORIGIN      
        1 ctataaacat caccccaaat aaaacagaaa acagtataag cattataaaa attatcaaca
       61 accttgatcc ttcttttata gattcaggaa acagtataat tttagtacta gataaattgt
      121 ttacaccgat tagtgttaaa atatctttat tcttcttgct aacataaccc tttatgcaca
      181 aaagaacagc tatacttaaa gtaacaaata aataacgtat tccaatagaa aaatcactat
      241 aaatactctc tagcatagga ccgacaattg aagaagtcac tactgcaaat gctggaccta
      301 tccaagcaac attagaatgt tctttctctc ttttcctttg taaatctttg ttgagtatta
      361 atctatttat ttcttctgca ggcaagttaa ttttcataac cttatggggg attatccaat
      421 taaaaatcgg aaaaaggtag cctccccaaa aagtatagtg atctgtgtca atcagataat
      481 aacctgattt tgattccaga ataacatatc tcaaagccga acgaaaattt ttcatgaata
      541 tccataatct cactgtttcc acacctaatt cctccaattc caattaaatg gatttatagc
      601 atcaccaatt atgttaactg cctgaccaac ctcattgata aaattggcac cactatccca
      661 tgcttcaaca atgctatata tctatcaaac aaaaaatgga aaactaaata ctcgcgcaca
      721 taaattttac attctgtttt ttataagact aataataatc attgaaaaaa tttcttatcg
      781 gtggcgcata ttcccaattg attaatgtga tcccatattc tgcaagtatt ttacgagctt
      841 cttctaagtc atagtgagaa aaatgcataa aacctgcaat acgatcacgg actgtgagct
      901 gtggcttgct tccaccatca ttcataaaat atccagcaga gccactactt aaagtgattg
      961 ttacatcttc actttctatt attaagaatt cataatgaaa tgctttcaac tctccactat
     1021 tatttaaaag ttttatactc caacttcgtc taggttgagt tgtcacattc cctctaaaac
     1081 ttcctataaa ttctgcaatc accgtatctt caatcaaaat tctttcctca tctatttcat
     1141 attcaagact aaacggaaat tctccatatg taatctctgg caatggtggt gctgtagttc
     1201 tccaaataaa tacaataact gtgaatagaa aaaatccaac gatcgatata aatgttatga
     1261 gacctgctcg aagtaaaacc cgatataata aaaatgctgt atttcgcttt gctatatcta
     1321 gaaaaataaa aagtactgca atcataatga tagtaaaagt tgtaaaaaag cacatttttt
     1381 gccctccctt tataaacatc gattctcaaa ttctaaacca aatcttgata gttcaagttc
     1441 aggtataacg tataccaacc atacatccca attactattt atgaacttat gattatcact
     1501 gaataaatca ctccatcccc ttgttaaaac ttctacatta attacacctg gttgttttcg
     1561 actagctaat ccaatgaact tatcaaccat ccttatccac caaccacgag aatcttgacc
     1621 agaagtaaga aaaacagttc tcaaggttga tcgagcagtt ccttccagtt tttaattaat
     1681 ctccagttat agataaatac ttgatcctat ctatatcagg acttctatat taagcaaaag
     1741 tttatgtata aaactaaaat cttcattcag ttgtctcccc gctttttata cgattgtatt
     1801 aaaaaacaat agaagccttt caacattatg ttactccagt aaagttggaa ttatagtttg
     1861 acggaagaaa agcaagtata gcttttaaaa aaaactgata cattcgcatc tcctgcttca
     1921 tgtatcagtt ttttctttgg attaaactgc ttcttcacgc agtttttccg caaattcatt
     1981 tattttgcga attcggtgat taattcccga ttttgatatt gcacctgagg gaatcatttc
     2041 ccctaattct ttcaagctga cctctggatg ttgaagccga agttctgcga tttcctgaag
     2101 tttttcagga agggcatgta gaccgacctt tgcttcgatc aattcgatgt tttcgatttg
     2161 tttagaagcc gcatcaatcg tcttgttcag atttgctgtc tcacaattga ctagacgatt
     2221 gaccgaattt ctcatatccc gtacgattcg aacatcttca aatcggagca ttgagttggt
     2281 tgcaccaatc aatgttaaga aatcagcaat tttttctgct ccttttaaat acgaaatata
     2341 gccattgcgc cgttcaagcg ttcgagcatg tagaccgtaa taatttaaca tatcgcaaat
     2401 gtcttggtta tgctgttcat aaatagaaaa tatttccaaa tgataacgac tcgtttccgg
     2461 attattgact gaacctgagg ccataaaagc accacgtaag taagaacgca ttttttgcga
     2521 atttcccata atctcgtccg aaacgtgtcc attgaacatc ataccatcca tgatatcaag
     2581 atccatcaac acatcttttg tgccttgctt caaccggacg atatagacat tgttcttttt
     2641 taatttcatt tttttacgaa cgagtagctc acttcgtacc tgataatgat ctttcaaaag
     2701 agaatagata cgtctggcaa ttgcagcatt ttctgtttgg acgttcaaaa taaactgctg
     2761 gttcacaata cctaaagagc cgttcattcg cagcaaagca gctaattccg ctttcgcatg
     2821 ttctcgatga acttccaaac cagttagttc tttcttcaca tctgcagcaa atgacatcct
     2881 attctcctcc tttctccaac aataaattgc ttaatatttt gaaccgaaaa ctaaacggaa
     2941 caattcttct actactttgt ctccatcgtg gaagacacca ccatctttca attctaaaaa
     3001 gtcggtggaa atcactcgac atccttcatt tctcaatccg ttgaagtcgt gtgcgacttg
     3061 tactagatac tcatcataga tctctgggtc catataatct tcaggcactt tttccgtatt
     3121 gaccaatact gtatcgataa aaggctgatt caaatgcttg tgtaaaacac gtatatgatc
     3181 ggcatctgtg aaatgttccg tttccccttt ttgggtcatg atattacaga tatagacggt
     3241 ttcagcagtt gtcttgagca ttgcttcgcc gatttctggt atcactaaat ttggaaggat
     3301 actggtgaat aaacttccgg gtcccaaaac gaccatgtcg gcgtccataa ttgctgaaac
     3361 gacttttcga gccgctttgg cttcactttt atcatttgtg ttgcagacat acacacggtc
     3421 aatggtttta cggttgatcg cgattttaga ttctcctact gcagtcgttc cgtctttaaa
     3481 aacagcatgc aaggtcaaag gagtttctga agaaggataa acatgtccat ctacatgcat
     3541 catttttgct aataattgaa tcgcctcata agtgcttccc cgcatctcgg aaactgcggc
     3601 aatgatcaga ttaccgatcg tatgattggc taaaaactga tcttcctttt tgaaacggta
     3661 ttggaaaata tcttcataga attgtggcat atccgataac gccactaaga catttctcaa
     3721 gtcaccagga ggagccatag cgatcgattc tctgattgca ccgctgcttc caccatcatc
     3781 tgcaacagtc actactgctg tgatatctgc tccttgattt cgtaaacttt tcaggataac
     3841 tggcagacca gtgccaccgc cgaccactac gatctttggt tttcttatcc ggtaggtttt
     3901 cattttcacg accggttcac cgtctctttc cttttatcct tgtcccgatg tgtcacattg
     3961 actttatagt ttttccctaa agcatttgcc aaacgttcag tcaatgccac agaacggtgt
     4021 tgaccgcctg tacagccgat tgcaactgtc aagctgcttt ttccttcttt aatgtatcca
     4081 ggcaatacag tttccagaag atccaaaaat ttatggtaga atgattgcgt ttcatcaaag
     4141 gacatcacat aatcatagac tggctgatct tttccggtca atggtcttag ttccgggata
     4201 taatgagggt tgggcaaaaa acgcacatcc atcacaatat ccgaatcgat cggcaacccg
     4261 tatttaaaac caaatgatac aaattcgatc cgaaatcctt ggtctccctt tgatttgaat
     4321 gactcattga ttttttcacg taattgtcgt ggtgtcaatg ttgtcgtatc aatgatcacg
     4381 gaagcttggg ctttcaagtc gtctagtatc gcccgttctt tacgtatccc ttcagtgatc
     4441 aaaccgtcca tcgccattgg atgtgctcgt cttgtttctt tgtagcgagc cactagttct
     4501 tcgtctgaag catctaaaaa taagatagaa gtgtcgatga agttcgtatt ttcgatttcg
     4561 atcagcatgt tttggatttc ttcaaagaag gaacgagaac gcaaatccac tcctaaagcc
     4621 atttttgtga ctttacctga ttctttgatc aattcccaga attttggaat caatcgaggc
     4681 ggcatattat cgatacaaaa atagcccata tcttcaaaac tttggatagc tactgttttc
     4741 cctgcaccac tcatacctgt tatgatgact aattgcaaat tatctgtcat atttacgaac
     4801 ccctctcaca ttgtgcataa taaaattata tcatcccggg cgtatcatta ccagttttct
     4861 ttttctttta caaaaagatt tggaccaaat atcttttagg atatttgccc caaatccaat
     4921 ttttttactt ttccgatgct gtatccaatg cctcgcttct ttcagctaat gcacgttcga
     4981 tcgttcgatc cgctaaaata gattgagcat cgatcactgg gtaatgatta tcttcagcaa
     5041 attcatgcat caaagataat tctgtgcaac ctaggatgac tttttcacag tttaggcgct
     5101 ctaccgcttc ctctaagatt tcgtaataga gctcttgatt caaataatcc gattccttga
     5161 tctcatgata gatcaggtaa ttgatttttt cttgaagcgc agtatcagga atcactgttt
     5221 cgaaaccaag atttttgact tcgcgttcat agattccagc tttcatactt ccttctgttc
     5281 ctagaatcgc tactctccct gtcgtatgct gacggacaag ttcatttgct gcttctcttg
     5341 gcatatgcaa gataggaata tccgttgccg cttgtaactc ttcaaaaaag tagtgtgcgg
     5401 tgttacaagt caacacaatg aagtttggtc gcaataaatt ttgtttctca atatcatcca
     5461 gcagaaacgg cattggattt tcttctgatc gatctaaaat ataagctgta cgatcaggaa
     5521 ctgttgcatg attgaataag acataattca aatattcttg atcttttgta gctttcgttc
     5581 ggtggttgat caagcgaaca aaactttctg tcgccatcgt gcccattccg cctaaaatac
     5641 tgaaaaaatt ctccatgaac tagccttctt tcacatgaaa atactttttg aatcttggaa
     5701 tatagttatg gaacatatat ttcatcaaca accagcgctt gattgatcgg tctttttcat
     5761 aaaatacagt agtaccgtaa cgattttctt tgatcatttg ctcagctagt tttttgtctt
     5821 cattttcccg agcatattct aaaaagattt ttttgggcac acccatccat aatcttgctt
     5881 tatctgattg attcgttcca taggtcgttt caacaaaggg tttgttgaac actcgatctt
     5941 ctgtgacaaa acgagccaga ttcaagccgt tcaatgtcac aaagaaactg ctacgacctt
     6001 gtctcaaatt gatttcaaat aatttatatt ctccatctct aggatcatac ttcatatcga
     6061 aattggcaaa gcctgtatat tcgatttttt ccaaaaatgc cttaatggtt tgatagattt
     6121 tttcgttata atctggcatg atcacaacgt aattaccaat cgatgctggt gtaggatctt
     6181 ctaatagtgg atgaccaagg cacatcatcc gaacttgatg atcttcatct acatacgcat
     6241 ttagcacacg catattacta tcatcacccg ggataaaatc ttgtacaatc atttcacttt
     6301 tataaccggc ttcgtatatc cggcctaaaa ttaaatcgaa ctcttctcta gtctctaaaa
     6361 taaaagcttt ttttcttcct tcaaattgga cagaaagata ctccacactg tttgcaggtt
     6421 tcaaagcaac tgggaattca aaaggcaatt cctgttccaa atgtccattt actaacattt
     6481 cttctctgac gatcaatgtt ttaggatacg gaagatcata ttcttcacaa acttcataaa
     6541 agcttacttt attgatcagc ctttcaaata aagaataatc aatatatgga cagataaaat
     6601 attctgacag ctcttgttta tgttgggaga tcaattctgc atatccatca ccacaagcaa
     6661 tcaaaagata ttttttactc ttatcagaat atctttcttt tgccaaacga agcatcgtct
     6721 cgataaatac agggtcttta tcaaatcctg gaataacttc tacattgaca attttactgt
     6781 agcgggtagg ggctaactga tccgaagcat atgcttggca gattttgccg tatgcttcat
     6841 taaaagaacg tgccatacca taaacgttca tgtcgcttcc taataatata gggataaatt
     6901 cttcattttc aatactgttc atcattatct ctcacttact cataatctct tgtttttctt
     6961 ttccaactac acaaggaata tcataccata aagaaaaaag caatcaaagg aaagtcctcc
     7021 gattgctcaa ttcttttttg aacggattga acttatagga agtttttatc tataccaatc
     7081 agtgtagaaa gaactaccat gtaatgattc tagaacactg atattaataa aacaagcaaa
     7141 aattcatttt tttatgtttt tttaactatc tcagctatct atcctcttta taccattatt
     7201 tttttcaaat agtgacctgt ataactttct tttacgttaa tgatttcttc tggtgttcca
     7261 gtcgcaagga tcgttcctcc accttctcca ccttctggtc ctaaatcaat gatataatct
     7321 gctgttttga ttacatctag attgtgttca atcactaaaa ctgtgttacc agcatctact
     7381 aatctttgta atacatgcaa caagcgggcg atgtcatcgc tatgaagtcc tgtcgttggt
     7441 tcatctagta tatagaaatt ctttccatta gagattttgt gcaattcact ggcaagtttc
     7501 atccgttgtg cctcaccacc ggacaatgtc gttgctggtt gccccatcgt cacataacct
     7561 aagccaacat caacaatcgt ttgcagtttg cgatgaatct ttggaatgtg cttgaagaat
     7621 tctacagcat cctctactgt catttccaaa atatcagcaa tgctttttcc tttgtaatgc
     7681 acttctaatg tttcagaatt atatcgttta ccatgacata cttcacaagg aacatagaca
     7741 tcaggcaaaa agtgcatttc gatcttaata attccatccc cgcgacaagc ttcacaacga
     7801 ccgcctttta cgttgaaact aaaacgccct ttcttataac cccgcatttt tgcctcgttc
     7861 gtttgagcaa ataacccacg gatatcatca aatacacttg tataagtcgc tggattactt
     7921 ctcggcgtcc ggccgattgg gctttgatcg atatcgatga tcttttcgat actttcgtag
     7981 ccggaaattg tcttgaattt acctggctta gcagaattct tatttaattt ttgcgctaac
     8041 gatttcttta agatactatt gaccaatgta ctctttccag aaccagacac acctgtgact
     8101 gctacaaatt ctcctaatgg aaattcaaca ctaatatttt tcagattgtt ttctgaagca
     8161 ccagtgatct tgattgcttt cccattacct ttacggcgtt cttttggtac agggattgat
     8221 tttttccctg aaagatattt ccctgtcaaa gaattttcat cattagctac ttcttcagga
     8281 gtgcctgcag ccacgatttg tccgccttgt tctccggccc caggtccgac gtcaatcaaa
     8341 taatctgctg cccacatcgt atcttcatca tgttcgacta caacgagggt gttgccaaga
     8401 tcacgcattt tctttaatga gccaatcagt cgatcgttgt cgcgttgatg caatccgatc
     8461 gatggttcat ctaaaatata caaaactcca gaaagattcg atccaatttg tgtagccaat
     8521 ctgattcgct gcgcttctcc cccagataat gttccggaag cgcgactcaa agttagatag
     8581 tctagtccca cattttccaa gaatgaaagt ctgtcattta cttcttttaa aatcggtttg
     8641 gcaattactt tctcttgttc agataacgtt aagtttgaga agaaatctac tgctttttga
     8701 atagacaact catttgtttg cccgatattc gttccattga tttgaacaga tagagcttgg
     8761 ggattcaatc gataaccttt acatgtctga caagttaatt ctgtcatata aagacgcatt
     8821 tgctcacgcg tgaaatcact gttcgtatca tgataacgac gctcgatatt cttcaatacc
     8881 ccttcgaaag tcgtttctac atcgcgaacg ccaccaaaat cattttcata atggaaatgg
     8941 aaaagatcat ctgtcccatt caagatgatc tcctgatgct cttccggtaa ttcttcgaat
     9001 ggtgtatcta aatcgatacc gaaactttca caagcctgcg ctaacatttg aggataatac
     9061 tgagagctga ttggattcca tggaacgata gcaccttgac taagtgtctt cgttctatct
     9121 ggaatcacta aatcttgatc gacttctaat ttgacaccta aaccatcaca gtctggacaa
     9181 gctccaaaag gcgcattgaa tgagaacagt cttggttcta gttcgccaac agtaaatccg
     9241 caataaggac aggcatagtg ttcgctaaac aacatttctt cttcaccgat cacgtcaacc
     9301 agagcatagc cgtctgctaa tcgcagggcc gcctctaaag aatcaaatag gcgagaacga
     9361 atcccttctt tcacaatgat ccggtcgatg acgatcgcga tatcatgttt tttgtttttc
     9421 tccagctcag gcacttcact taaatcatag atctcaccat cgactcgaac gcggacgtat
     9481 ccctcttttt ggattcgttc gaatattttt ttatgttgtc cttttttctt taccacgatc
     9541 ggtgccaaca cttggatctt tgtgcgctca ggcaaagcca ttacttgatc tgccatttga
     9601 tctactgatt gactggtaat ctcgatatga tcgttgggac aaatcggatg tcctacacgt
     9661 gcaaacaaca agcgtaaata gtcattgatt tccgtcacag tacctactgt cgaccgagga
     9721 tttttacttg ttgttttctg atcaatagaa atcgccggac tcaatccgtc gatgctatct
     9781 acgtccggct tatccatttg tcctaaaaac tgacgagcat aagcagaaag gctctctacg
     9841 tatctccgct gcccttcagc gtacagcgta tcaaatgcta gggaactttt tccagaaccg
     9901 gacaaacctg taacgaccac gaatttatct cgtggaatcg ttacatctat atttttcaag
     9961 ttatgggcac gtgcaccatg aatcgtaatt ttatcgttag ccatgttgtc ctcctacttt
    10021 gaagctttta attctaaaat catatctcgc acattcgcgg ctgtttcaaa atccaaagct
    10081 tttgccgcat ctttcatttc tttttctaat ttcatcaata acgtgtcttt ttcttccttc
    10141 gtcatttctt cgtacgagac ttgtaccgct tcttttgtat catcttccga ttctttcgta
    10201 atagaaatca aatctcggat ttctttaatg atcgtttttg gaacgatccc atgttcttca
    10261 ttgtacttct gctgaatcgt acgacgtctt gacgtttcat ccatcgctag acgcatagaa
    10321 tctgttactt tgtctgcgta catgattact ttaccttctt cattccgagc agctcgtcca
    10381 atcgtttgga ctaaggaacg ttcactacgt aaaaagcctt ctttatccgc atccaagata
    10441 gcaacaaggg aaacttcagg tacgtctaat ccttcacgaa gcaaattgat tccaactaac
    10501 acatcaaatt cacctaatcg aagatctcga atgatttctg ttcgttccag cgttttgata
    10561 tcactatgca aatatttgac tttgatccct aattctttga aataatctgt gaggtcttct
    10621 gccatttttt tcgtcaatgt cgttacaaac acccgctggt ctttttcgac tcgttcattt
    10681 atttcgccta ctagatcatc gatttgtccc atgattggac gaacttcgat cactgggtca
    10741 agcagccctg tcggacggat gatttgttgg ataacggtat ctgtttgttc atgttcatat
    10801 ggtcctggcg tcgcagagac ataaatgatc tgattgacat gtttttcaaa ctcttctaac
    10861 cgaagtggcc gattgtctaa agcagatggc aaacggaaac cgtaatctac tagcatctgt
    10921 tttctcgctc ggtcaccatt atacattcct ctgatttgag gcatggttac gtgcgattcg
    10981 tccgccacga tcaaaaaatc ttcaggaaag aaatccaata gcgtataagg cggttcacct
    11041 tctttacgtc cgtccatatg ccgagaataa ttttcaattc ccgacgtgta gcccatttct
    11101 aacatcattt caatatcgta attggttcgc tgttctaaac gttgagcttc cagaagtttg
    11161 ttttcatttc gcaagacagt taaacgctgt tctaattccg ctttgatatt cgctacggca
    11221 tgctccatat gttcatcatt cgtcacaaag tgagtcgccg ggaagattgc tacgtgttcc
    11281 gtttctccta aaacttcacc tgtcagtgca ttgacttctc ggatacgttc gacctcatct
    11341 ccaaaaaact ccacacgtaa ggcacgttca tctcttgaag ccggaaaaat ctccacgaca
    11401 tcaccgcgca ctcgaaaacg accgcgctga aaatctatat catttctttc gaattggata
    11461 ctgactaagt cacgaatcaa ctgattgcga tctagttctg ctccctgtcg aatcgaaact
    11521 acttgttttt ggtactcaaa aggcgagcct aatccaaaaa tacatgaaac ggatgcaatg
    11581 acgatcacat catttctttc taataatgaa ctagtagccg aatgtcgtaa tttgtcgatc
    11641 tcatcattta cacttgaatc tttttcgata tacgtatcgc ttgaaggcac ataagcttca
    11701 ggctgataat aatcataata agaaacaaaa tattcaacag cattgttagg gaaaaattcc
    11761 ttgaattccc cgtacagctg accagccaat gttttgttat gggcaataat cagtgttggt
    11821 ttattcactt tctcaataag attggaaatc gtatatgttt tccctgttcc agtcgcacct
    11881 aataagattt gtgctttttt cccgccgact acgccatcca ctaattggtt aatcgcttca
    11941 ggctgatcac cagccggttg gtatttcgag acaagctcaa agtgtcggga ggtatctctc
    12001 tcaatcattc ttcgtcctcc ttttcattca ttccttttca ttttacgacc aataaaaaga
    12061 aaaggaaagc aaaggcattc cttactaaaa aattatacca caccgaacat actttcgcca
    12121 cttttttatc ttattataca tgttatgttt tataacataa aatgttagaa actcgcattt
    12181 ttttcatttt ttcgagctta cagtcttgtc tgattcagca cttttcgcct ataataataa
    12241 aatattggaa atttaggagg ttgattatga aaagaaagca tttatttcac tcatttgttt
    12301 tcttaatgac aggacttgtg acacttgcgt ttggtcatgt tgcacaagct gacaacacta
    12361 caacggcaga gtcaagcaca agcgagacaa tgcaaaaaat agagcccaaa aaagacgtat
    12421 acgtaattgc cagtgactct gcttttgctc catttgaatt tcaaaacgca aagggcgagt
    12481 acgaaggcat cgatgtaaaa ttgatggaaa acatcgccaa actgcaagga tttaacatcc
    12541 gaatggacta ccgtggtttc tctgctgctt tgcaagcttt ggaatcagga caagcagacg
    12601 gaatgattgc cggaatgact gtaacagatg aacgaaagaa aagctatgat ttttctgatt
    12661 cttactttga tagcgggatc caattagctg tcaaaaaagg agatacttcg atcaagtctt
    12721 atgaagattt gaaaggaaaa acagtcggag caaaagttgg taccgaaagt gctgaatttt
    12781 taagcgacca tgaatctgaa tatggctatt ctatcaaata ttttgatgct gctgatcaat
    12841 tgtacgacgg gttaaaagtt ggcgcaatcg atgcaatgat ggatgattat ccggtaatcg
    12901 gttatgcgat caaacaagga caagaattgg aaacaccgat caaaaaagaa tctggcggaa
    12961 aatatgcatt tgccgttaaa aaaggacaaa atcctgagct tcttaatatg ttcaatgaag
    13021 gattgaaaga attaaaaaga acaggcgaat acgataagat tattaaagaa tatgtagcgg
    13081 atggttcaga aacttccagt gagtcttcca ctgctgatga atcaacattt cttggactta
    13141 tccaaaacaa ctatcaagca ttgttgaaag gactttggag aacaattctc ctaactttga
    13201 tctcctttgc tttggctata gtaatcggtg tgatttttgg attattcagt gtagcaccaa
    13261 tacgcgctct tcgcacaatt gctagtattt atgtcgatat catccgagga attccaatga
    13321 tggttcttgc gttctttatt ttctttgggt tgcctggtat cgttggattt acgattcctg
    13381 acttccttgc tggtgttatc accttgactc ttaacgcaag tgcttatatc gcagagattg
    13441 ttcgaggcgg gatcaacgcc gttcctgtcg gacaaatgga agcttccaga agtttaggtc
    13501 tttcttataa tcggacaatg caaaaaatca ttttgccgca agcgatacgc atcatgatcc
    13561 catcattcgt caatcagttc gttatctcat taaaagacac aacgatcatt tccgcaatcg
    13621 gtgtagtcga attgctgcaa actggtaaga tcattgttgc acgtacaaca caaagtacgt
    13681 atgtttactt gatcattgcg atcatgtact tgattttgat cacagcattg acaaaattag
    13741 caaaagtttt agaaaagaag gtgaagtaag atggcagaaa aaatcttagt tgagcattta
    13801 gtcaaaaaat acggcgataa cacagtatta aacgacatca atgtatccat caacgaagga
    13861 gatgtcgtct gtatcattgg cccttcaggt tcaggaaaaa gtacattctt gcgttgcttg
    13921 aatcgtttag aagaaccttc tgacggtgaa attattattg acggcgccca cttgatggat
    13981 aaaagcacag atatcaactt ggtgagacaa catatcggaa tggtattcca acactttaac
    14041 ctattccctc atctttctat tttggaaaac atcattttag caccgatgga cctgaagaaa
    14101 gaatctagag aagaagcaga gaaaaaagca atcaaattac tgcagacagt tggtctagaa
    14161 gataaaaaag atatgtatcc tgaaatgctt tctggtggac aaaaacagcg tgtggctatt
    14221 gctcgtgctc tagcgatgaa ccctgacatc atgctttttg atgagcctac ttctgcactc
    14281 gatcctgaaa tggtcggtga tgtcttgaac gtcatgaaaa agttagcaga acaaggtatg
    14341 acgatggtta tcgttacgca cgaaatgggg ttcgctaaag aagtggccaa tcgcgtcatg
    14401 ttcattgacg acggaaactt tttagaagat ggaacgcctc aacaaatctt tgaaaatccg
    14461 caaaatgaac ggacaaaaga tttcttgaat aaagtattaa atatttaata aaaaccaaaa
    14521 atgcacggtc gccatgaagg gaccgtgtat ttttatcttc ttattttctc acctaatcgt
    14581 atcagccgca tcgcttgttt tcctgcacaa acaagcaatc gctctacctg ttccatcgca
    14641 taagaaagta ccatcggttc attgatgata tcaagtacat agtcgatacc accctcactt
    14701 aattgagctt gatttttctt ctccatatta tgtagttgtg ggacaacttt ctgacaatca
    14761 gcaattgtgt caagaacgga tcaatccttt attggagttg ctcgaaaggg tcttctctta
    14821 ttacggacag gctttgctca ctgtacatag acaacaaatc attatcctag tcaatcggat
    14881 ttccagagcc tcattgctat cattgcttga taaaatccag acaaagttta ataaaatgta
    14941 tcagttacag ctaaactttg gaattgggtc gctttgttat acagagcaag agacaccgca
    15001 atctttcctt catgccaaac aagtttgcga atggatagct ttccatcaat ctgtgaacga
    15061 gatccgcttt tttgaagatt tagacctcgg gatcgtttta ccagcaatcc cgtcagatca
    15121 acgaacatta tatgtaaaac gtattttgaa aagcctgaca gaagaagaag tacatttgtt
    15181 caagaagact ttggcatgct tcagtaaaaa taacggaagc atcaaaaatt gctcagaaga
    15241 attatttatt cataaaaaca ccttgcaata tcgattgaac aagttccatt ctctcactgg
    15301 ttatacccct agaaactatg acgattatca tattctaaag ctggcttttt tgttggtaca
    15361 aacatgacaa ctacaaaaaa accaggcgaa catatgattg ttcgtctggt ttttaattat
    15421 taatgactta gcgtttttac tagaaaaact acttccgctt tttcccgcca aaagcatctt
    15481 taaacttatc gaagaaaccg tcttcttgct gttcttcaac tttgatgccg ccagcttcag
    15541 cgaatgcacg taatgcttct ctttgttgtt catttagatt tttcggtgtg atcagtttta
    15601 ctttgacatg ttggtcgcct gttgcaccac cacgtaactt cggagcgcct tttccacgta
    15661 aacggaagtt cgtacctgtc tgtgttccag cagggatctt caatttcaca tctccatgga
    15721 cagttggtac ttggacttca tcccccaaag ctgcttgtac aaaacttaaa ggcaattcat
    15781 agtaaatttc agaaccttca cgatcaaaga tatcactttc ttctacacgg aagaccacat
    15841 acaaatcacc aaatggtccg ccgttttctc cagcttctcc ttgaccagct aaacgcattt
    15901 gttgtccttc ttctacacca gctggtacat tcactttaac tgaatgtgct ttcttctcat
    15961 gtcctgagcc atgacaggtt ggacaaggtt ctttgatttc tttccctgtc ccatgacaaa
    16021 catcacaagt ttgacggctc atcactcgtc caagtggtgt ttggcgttct acattaatcg
    16081 tacctgcacc atgacattta tgacaagtag ttggttgtgt gcctggtttt gcaccgttcc
    16141 caccacaagt atgacagatt tcttcccgat tatacttgat ttctttttct acaccaaaaa
    16201 tcgcttcttc aaaagacaag tcgaccgtat attgcaaatc agcaccttga cgaggcgcat
    16261 ttggatcgac tgaccgaccg cctcctccaa agaaagagtc gaagatatct tcaaaaccac
    16321 cgaagccgcc accagagaag ccgccgaatc caccaaatcc gccaccagct ccaccagcac
    16381 cgtaatttgg atctgtgcct gcatgcccgt attggtcata tgcagcgcgt ttttgcgggt
    16441 cacttaaaat ctcatatgct tctgatactt ctttgaattt ttcttccgca tcaggttctt
    16501 tattgatgtc aggatggtat tttttcgaaa gcttacgata agctttcttt atttcatctt
    16561 ctgatgctcc ttttgagagc cctaagactt cataataatc acgttttgtt gccataggct
    16621 ttcctcctat tggttctcat cattttcacg tcgcttgtta tcatatcata ttttgtttga
    16681 aacaaaaacc gatacttcaa actatttttc aaaagaaaaa gccaaagtag caactttggc
    16741 cttctctcga aattcagtga actgattatt tatcgtcgcc atcgacttct tcaaaatcag
    16801 catcaacgac atcatctgct ccgccttgag ctgcttctgg gttttcttga gcttgttgtt
    16861 gtgccgcttg ttcgtatagt ttaacagtca agttttgaac gatttcgttc aatgcatcgc
    16921 gtttagtttt catttcttcg atgttgtttg cttcaacagc ggctttcaat tcatcgcgag
    16981 ctgtttctgc ttttttcact tcttcttcgt ccactttgcc ttctaattct ttcaatgttt
    17041 tgtccacaga gaatagcaat gcatctacat cattacgtag gtcaacttcc tctttacgag
    17101 ctttatctgc ttctgcattt gcttctgcat cttttaccat acgttcgatt tcttcgtctg
    17161 ttagacctga agaagatttg atcgtgattt tttgttcttt ttgtgtacct agatctttcg
    17221 cagatacatt tacaatcccg tttttatcaa tatcgaatgt tacttcgatt tgtggaatac
    17281 cacgaggagc tgctggaata tctgtcaatt ggaatcttcc tagagttttg ttgtcagcag
    17341 ccattgggcg ttcaccttgt aatacatgga tgtctactgc tggttgatta tctgccgcag
    17401 ttgagaatac ttgtgattta cttgttggaa tcgttgtatt gcggtcaatc aatttagtga
    17461 acactccacc cattgtttcg atacctaatg acaatggtgt aacgtcaagt aaaacaacat
    17521 ctttcacatc accagtgatc acgccacctt ggatagcagc acccatagca actacttcat
    17581 cagggttaac tgatttgttt ggttcttttc ctgtttcttt acgtactgct tctacaactg
    17641 cagggatacg agtagatcca ccgactaaaa taacttcgtc gatttctgat tgtgataaac
    17701 ctgcatcttt tagcgcttga cgtactggta cttttgtacg ttctactaag tcagctgtta
    17761 attcatcaaa ttttgcacgt gtcaatgtca tttccaaatg caatggtcca gattctcctg
    17821 ctgtgataaa tggcaagctg atttgtgtgc ttgatacgcc agataaatct tttttcgctt
    17881 tttcagcagc gtctttcaag cgttgtaaag ccattttgtc ttgagacaag tcaatgctgt
    17941 tttctttttt gaattctgct accatgtagt cgatgatttt gttatcaaag tcgtccccac
    18001 ctagatggtt gtcgccagct gttgacaata catcaaagac accgtctcct agttcaagga
    18061 tagatacgtc aaaagtaccg ccaccaaggt cgaatactaa gattttttcg tcgcgatctg
    18121 ttttatctaa accataggca agagcagctg cagttggttc attgacgata cgttctactt
    18181 ctagaccagc gatcttacca gcatcttttg ttgcttgacg ttgtgcatca ttaaagtaag
    18241 ctggcacagt gataactgct ttttcgactt tttcacctaa atagtcttct gcgaatcctt
    18301 tgatatattg aaggatcatt gctgagattt cttgtggtgt atatgattta ccttctacat
    18361 ctactttgta acctgcttca ccgatatggc gtttgattga tgaaatcgta tttgggtttg
    18421 tcacagcttg acgttttgca acttccccta cttggatttc tccatttttg aatgatacaa
    18481 cagaaggtgt tgtacggttt ccttctgggt tagcgatgat ttttgcttcg tttccttcca
    18541 atactgctac tgcagagtta gtcgtaccta agtcaatacc gataatttta ctcataatta
    18601 acgtctcctt ctttaattga aagtgtaagt tttatatccg cacaattatt gtgcaacaat
    18661 gaccatggtt ggtcttaaca cgcgatcatg taatttgtag ccttcttgta gtacttctac
    18721 aatcgtatcg gctggtgtat cttcagtcgc tggaacagtt tgtactgctt gatgaagatt
    18781 aggatcaaag gcttctcctt tagcagggat tttttcaatt ccttcttctt ccagtgcgtt
    18841 acgcaaactt tccaagacca tttccacgcc ttttttcaaa cctgcccctt gatcatctga
    18901 cacttctgtg gctaatgcac gttccaggtt gtcaattgat ggaagtaatt ttttggctaa
    18961 atcttgtgaa cggtattttt gtaattgctc acgctcattt tttcctcgat ttgccatatt
    19021 tgcgatttca gcacgagccc gcaagtattt atcttccatt tcttctaact cagcttttaa
    19081 tttcgctgtt tcgaattctt ccgcttcagc ttctgaaata cccgaatctt ctgcagcttc
    19141 gacatcgatt tccggttctg gctgagcatc tgtcatttct ttatctagtt cttcttgatt
    19201 ttctttcacg atacagtctt cctttcatta ttcagtcagc tgtttgattg ctcttactaa
    19261 gaaagagaga acgatcagct gcaaatagct tcgttattca cattacgagt ttgacaagtc
    19321 aagcgaacgg tagtaatcag caagtttagc tgctagttct cttcgataaa catcgactag
    19381 accgaacatc cgagaataag gcatactagt aggccctaac aaggctattg tacctcttcc
    19441 atgaccatct atctcgtaac ttgcttgaat catactcata ttctgcaata aatcattgcc
    19501 taattcagca ccaatcttga tatgaatatt gctatccatc ggagtgatca tttgtgtaag
    19561 tccgtctgag tctttcataa aagaaaacat cgatttgaac tgatcaagat cttgacgggg
    19621 ctcataatcc aagagattca tttgtccact gacataaacc ttatcttcaa aaacatgacc
    19681 aagaacggtg tcaaataact gagacatccc ttctgtcgtt tggaaatatt tatgaagaat
    19741 catcggaatc tccgtacgaa gtttatggta caccgtcatc agaggatctc cgactagacg
    19801 gtcgtttaca atctgtacca ttttttctag ttcctgactt cccatatatt cgggaagagt
    19861 gaacacttgg ctttctacat tccccatatc tgttacgacg atagcaataa tctgtcgatt
    19921 attcaagggt acgatacgaa agccagtcag tcggcggtct tttatttcag gtcccaatga
    19981 aaaagtcgta tagcttgtca gctcagataa tatctcagca gattgcttaa taatctcatt
    20041 gatttcatga aattctctgc ctagagactg acgaatcagc agcaaatcat cttctgctac
    20101 gcgagcaggt tttaacaaat gatccacgta ataacgatag cctaaagcag atggaatccg
    20161 cccagaagaa gagtgagtct tcaacagcaa tccttcatct tctaatgctt tcatatcatt
    20221 gcgaatcgtt gctgagctgg ccttgactcc ctcagacatc aatgttttgg aaccaacggg
    20281 cacgccacta ctcgtatagt gttggatgat cagacgtaaa atgtcgtttt gtcgctttgt
    20341 taacatcttc ctcacctctc attagcactc atatattcta agtgctaatc cacttataaa
    20401 tatagcaaga agcccttctc ctgtcaagag aaagactcca ttttttagca ctctaaacac
    20461 aagagtgcta attctaaata attgatgtaa atccagttat atcaacgttt caatagtcct
    20521 ttattgtatt tttgaacttt ttttatttaa attcagataa aaaacaaata ttctttaaac
    20581 tatttttcaa acaaaaagcg ctcaaacaca ttgttcccca aaaaggtccc tcttggtgtc
    20641 aaataaacac ggtcttcttc attaacaagt aacccttctt gctctaattc ccttagcaca
    20701 tcaccgtaca ccgattcaat tgttttttga tagcgatcat agaaatgttt tttagtaatc
    20761 cctgtttttt ttcttagtcc taagaacatt tcttcttcta tttgattttt tcgtgtcaat
    20821 ttttcttctt ccaataccgg gcgttcattt gctcgtaatg ggcgtaaata gtgttggatt
    20881 ggtcctttgt tgcggtaacg aatatctcca agataaccgc tagcaccagc tccaaaccca
    20941 aaatagtggg cattgttcca gtacatgagg ttatgttgag attcatgtcc ggagagccca
    21001 aagttactta tttcatattg gtgacgtcca tgcttttcca ttgcttcaat cgtctcttca
    21061 aacattctgg tttccgtttc ctgatcaggc agttcgagtc ttccttgtcg tacccagttc
    21121 atgaacattg ttttgttttc gaggatcaat gagtacaaag aatagtgagg cagatccaaa
    21181 gccaaagctt tttccaaagt atccagatat ccttctagtg tttgtcccgg taatgcataa
    21241 atcaaatcga tgcttacatt ggtaaaattt tctgcttcta aaaattgcat agtttgatac
    21301 acatcttctg cggtgtgttt acgtccaatt tttttcaata agcgattatc aaatgtctgc
    21361 actcccatgg ataaacgatt gacgccatag tttttcatta cttgaagttt ttcacgggtc
    21421 aaatcacctg gattcgcttc tacagtaaac tcattaccat tttgaaaagg caggatctct
    21481 ctagcacctg ataacagtcg atcaagttgt ttagcagata aagaagttgg tgtcccgccc
    21541 cctacgtaaa gtgtttctaa attcgctgtc ggatgacttt ctagcattat tttcatttca
    21601 ttcagcagca tttccacata ctcatctact ggctgccctt ctaaaaaaac tttattaaaa
    21661 tcacagtaat agcagatatg ctcgcaaaat gggatatgaa tgtacgcaga aaccttgttt
    21721 tctgcgggat ttattgtttc tatcattgaa attctttctc cttacgtcga aaagtcgtgc
    21781 ctgttttcga ccttcttaaa atcgcgttca agcaccaact cattgaaata agccgcatat
    21841 ttagaatcaa ggaaacctag ctctaaaaat gcttgcttat tgtcatcgga gctacacggt
    21901 gcttttacag cctctcgata aacggtaatc gcaaagctga ccttcggcat taagtcaaaa
    21961 tctgcaaaaa tatgaaaagc tattttcaca gattcctcct taagtgctca gaccacaacg
    22021 ctttgcttac aacctctcat atacgcatac taaacgtatt tggcgaacaa atccactaaa
    22081 aaatccaaga atcgacttct tggatgattt tttctttcat taaactggtt acctagttat
    22141 atatctctag ggttgttttc atgtctgagt gcccgatatg atttattttt cgtttctata
    22201 attacttttt gccttccagt ttcttttaat attgtactca agcaagtggg aattggttct
    22261 tttgtcatcc atgtatgcaa aatgttataa tgctggtaaa caaaaatgat tacctgtcat
    22321 ttttatttag ttcgtattta attaagttga ctatctgtat actctgtcta aaacttaaga
    22381 attgttgttt tcgctgtcgc tacccaattt taatgaatgt ctgtaggtta aaactgttgt
    22441 ccttgttata gatagtaaag gagagcttga aaatgaaaac tgcgattacg tttctattag
    22501 aggaatatgc cgattgggaa ggtgcttata ttactagcac actaaaccaa aatgagaaat
    22561 ggcaaaacaa aactgcttct atccaatcag aggtcacttc cattggagga ttaaaaacaa
    22621 aaatcgatta cttaatcgaa caaatacctg aaaaagttga cctttttatt atgatcggtg
    22681 gcaattcatg ggacataaaa aatcatcatt tatatcaaat aatcgataaa ttgttaaaaa
    22741 cagacgtacc agtagctgct atttgtgggg cagttgatta tttagctcag agcggattat
    22801 tgcaaggtta caaacacacc ggaaatgcgc aatttccttg gttagaatcg gaaaattatc
    22861 agaataaaga agattttata gaacaacaag ctgtgaaaga tcgtaatttg attactgcga
    22921 atggaacagc tcctatagaa ttcacagact tgattcttca agcagtccat tttgaaacag
    22981 aagaaataag agaaaaaacg attcgtctat acaaacttgg attctatgat tactataaaa
    23041 agtacggaga tcctttctcc taatcattct cttcaattaa atactcctta tcaatagtgt
    23101 gacaagtaat tttactgatg attatttgtc acactttttc tgacatttat caaagaagat
    23161 acactctatt tatattcata gacaaggttt tacggattca aaaattcagg attatgctat
    23221 actggtatta aaaaaataat gaggtatttt atatgaaaaa gttaggtttt attttattgt
    23281 tggtctcttt attccttgta ggatgtacgt ctcctagtaa agaaaatagt gatccatctg
    23341 cgaccacaga caaaagttca atcagacaaa ccagttcagc tgaaaaatca agtactcaga
    23401 aatcagcttc tactgaaacg aatacatctt caacaagcag taaagtctca gagcccaata
    23461 cttcttctac atctagtagt acagttgaga caaatatttc ttcttcaaca atagacacaa
    23521 cctcctcaca gtcttctcag tcaatagatc cgttagcagg atattctgat ctacaaattg
    23581 agtacgcacg tgtttggcta gctattagag gtaatacttt tagagataca tcgggtgatt
    23641 tcgaattaca tgttattcat tatcctgcag gaacacctat cgccccttat gatgcaggga
    23701 gtgcagtcta tccgaaagat gtggttatgc tcactgggaa atacagttac cagggagttt
    23761 tagtgtattc aagtaaccat gacgggacaa tcactagtta tccagttcct tcacattggc
    23821 aaatgcctgc agatcaaaca tcttatccag cgttcattag agaaacaact caagaaatca
    23881 ttgataatgc atctgtagta gctattccta caggaaatcc caatgacgtg aaacagttaa
    23941 tcgatgtgac agttatagat aattagactt tctaatatgt tatacaaaaa gaagctgaca
    24001 gcattttgtc agcttctttc actttctttt ctatttagat ttattggtct ttgatagact
    24061 ccaaggcagg aaaaaatttt ttaaataaac gtttgcaaaa cagtcgcttt tctatcttct
    24121 accgctactt ctgcataggc accattaatc aatgtcagtt gtggcggtac atgaccacaa
    24181 tcaatatcat acaagatcgg tagttttaat tcctttgaca gatcttcgta tacatccttc
    24241 attttataat ctaacaaatc ctctgccgca cttctaccga acatgatccc cgagctgcca
    24301 tcaaaccagc ctgccagttt catctgaaca agtgatcttc ttaaatcaac tgacgatagc
    24361 tcacagtttt ctagaaacca caagatcggc tttccatcat tatactttct tttaaaagat
    24421 tggacatctc cataaggagt accgattaaa tgcctgatcg tatcaataca accacctaat
    24481 aatcgtccct tcatccttac tgcatctccg ctgactgatt gccaatttgt tggttcagtg
    24541 agatggaaaa cagaagatga tgaatgctca tggggccaca ctttttgata cttttcagaa
    24601 gattgctgta gaatcgattc tccttctctt gttttcagta cactttccca cattgctgtc
    24661 gtttcatcca agtactctcc tcttaaatca ataaggttag ttccatgtgc agtggctatc
    24721 cctgttttta atgtgacagc aagtagcaac gtactaatat ctgaataacc tactatccat
    24781 tttggttgta gagcatcaaa atcgacaaaa tcgagaatct caatcaataa ttctcctccc
    24841 caagtcggaa agatcatttg gatattttca tcttgcatca tttgattgaa ttcatctgct
    24901 cgttttcttg ctggacctga tttttcctta tcttgcgtcc aaagcgtctt tccagtaact
    24961 acttggaaag atttttcttc cattctcttt aaagctgatt cgagtaacga atggtgttcc
    25021 tctgatacgc ctgaggatgg tgcagtaacc ccaatcgttg catttctttc taataatgga
    25081 taacttatca tgttgcttca cctccaagta tgcactattt tacttggtta attgtttttt
    25141 tcgtttgccg gcatcaaaaa tatcggcatc tcaagtagct ggatgatttt gtttaagtca
    25201 accgtttgga tgaccatcgt ttgatctggt ctacctggtg caaaaacaag tttttcattt
    25261 gataagagct cttcatcaat aataatcgga atctgttttt cataaccaaa cggagaaaca
    25321 gcgccctgct tttgtcccgt ttgttcttcc atgcgttctg atgaaacaat agaaagcctt
    25381 ttaccgacga tcttccctaa tgctttgaaa tccgtttgtt tcgtagtaaa agtcagatat
    25441 acgtagttat tatctttttt atcttttaag aataagcttt tggtctctgt acctgtaaat
    25501 ccttgttctt tctttattac caaagcatct tcatttgtat aaatggctcg atgatgatac
    25561 aactcaaaat atatattttc gtgtaagaat ttctttgcca agtcaatcat ttttatgtct
    25621 cttttctatt ttattatttg agacatctta tcatataaat atagcggtta caacattact
    25681 tgtgttttgt tcgtttttta tacataacta ttgtttttct ggtaaaataa atcaaaccac
    25741 ttaatggagg cgttttagaa tggaaaaatt tcagccgatc atcaatcaaa tcaaagaaaa
    25801 agaacatcaa caaaagatca aagacctttt tgctaagata acagaaacgt atccccagct
    25861 agacacaact gtaaaatgga accaacctat gtttactgac catggtacct ttattattgc
    25921 atttagtttt gctaaaaatc atttttctat cgcaccggaa aaagcagcga ttcgtgccct
    25981 tgaaaaaaat atccaagaag caggctacgt atatacggat aacgtcatca aagttccttg
    26041 gaaaagtgta atcaactggg aattgattga acaattgatt tcatttaata ttgaagataa
    26101 aaaaggtcat gataaatttt ggcgataaag ctttatacga ataaaccttt tactggcgag
    26161 gaaactattc atcaccttat acaggttttg ttcaatccta tcctttttat catccctggt
    26221 taaacactta attgacaaag tatctgctat ttttataagg agtctttctt gtgctgaaaa
    26281 aaatcactga ttgaatggct ttgaattttc tacttagtaa aattattttt tcagcaattt
    26341 tcctgcaaaa cttttgaata aggaaaaaat acgagaaaat atcagtgatc tttcataata
    26401 ctgcccatta ttttcaggta tatttaaata taatatcact ttaggagaga acgaatttct
    26461 ttagagaaat aaaagttaga attttctgac ttgattttta caatgacctt aattaaaatc
    26521 gttctttcta catttcgtga ttaagcaaat atcaactaag tcagtagaac cattcacata
    26581 ggagggtgaa cattgaaaga tttttactca gtaaatgaat tagccgaaca attaggtgtt
    26641 actacacgtt ctatcagaaa ttatcttcat gaaggaaaac taaaaggaac aaaggttggc
    26701 gggcaatgga aattttctga acgtaatctt tttgagttcc tatacggaga tcaagcagag
    26761 gaagcagcaa aagaaatgca gcgattcatg ctaaatgcac caatcacgat gcgtttcaac
    26821 cttcaatatc gtgattttac agcaatcaat caattccgag aacaattagt ccagtaccat
    26881 aacgatgttt acgcaaataa aaaagaccgt cttttacaat acgatcttta taaagacaat
    26941 catgcggaga tactaatcgg tggtaacttc aattatgtcg taaactttag tcaatggatc
    27001 aatgaaaaat tattgatcca gacagatatt tcccttgtat cttaaacaat taaaaagcgc
    27061 tagaaattcc agagatgttg gaaattctag cgctattttt ttataagtac ttactgtttg
    27121 gttcaaacaa atattttttt aataaatgaa attttaccat ctttatcctc aaataaagac
    27181 cgtgaccatg cttcctacta cgatcagcaa taatccgata atcgttaatt ttttttcttt
    27241 tggtgtctta ttttcatgca ggatgtacat accgcctaat gtagagataa ctacgtttag
    27301 ctgtgtaatg atatatgcag tagcaacccc attttcattt gctgaaaaaa tataagccaa
    27361 tgctgacaca ctaaagatgg ctccaacgat cgttgctttc caactcttgt cttcagaaaa
    27421 tgcggttggt ttacggaaaa tcacataaat cactgcccct aaaaagacac cgatcatttg
    27481 cggaaagaaa atggaaagtc cgcttgcatc aactagttta ggcaatgcac tgtataccca
    27541 ataaccaata cttgttgatg ctaatagact aattcctttt gtgataccgc ctttttttcc
    27601 aggatcatca ctgattgccg ttaaagcaga accaaataca agaagaatga ttgctgctgc
    27661 tccaatgatt ttccccatac ttccagacca ttctccaaaa gcgaagacac caatcaacga
    27721 ggttccgact aactgtaatg cagtcgaaat tggcatcgtt ttagaaacac caatcaagtt
    27781 gaaagatgta tactgtcctg tttgtccaat aacccaaaat gcaccagaaa gtaaactaat
    27841 caaaaatgta gtcactgaaa taccagctgg agaagcgaat aattgaacga gtaagccgac
    27901 aagcaccgct ccaataccag ttcctaatat ctcatttgtt ggtctgccac caatcttttt
    27961 caaaatcagt ggctggatcc cccagccaac tgccgggatc aatgcaatca ataaacccat
    28021 ttttattcac ccttatcctt ttccaccttg gaaagaagga tataaagtca tcccaccatc
    28081 tgcaaatagt gtaatacctg taacataact ggattcgtct gaagccaacc atgcagctgt
    28141 cgccgctatt tcttttggtt cacctacgcg tcctagtggg atcatacttt ccaagagttc
    28201 tttttgttca ggatcatcaa attttgccgc attaataggt gtacggatag caccagggcc
    28261 tatactattg attctgattc ccttcggtgc atactccatt gctaccgttt cggtaaataa
    28321 ttttaccccg ccttttgaag cagcgtaatg agcaaacgtt ggccatggga tctgttcatg
    28381 aacagaagac atattgatga tatttccttt tttattattc tctgtaaagt aatttaaagc
    28441 cgctttcgtt ccgataaaaa cgccagtcaa attgactttt aacactcttt cccaatcttc
    28501 aaggctaagt tcatgggttg gatgctgatt ttccatccca gcattattaa cccaaacgtc
    28561 cagtgtccca aaattttcta aagccgtatc aagtaaacgc tgtattcctt cttcagaact
    28621 gacatctgct tgtacagaga ctgcttttcc gcctgcctct tcgattgctt tgactgcttt
    28681 ttctgctcct tctttatccg agttatagtt gacaactaca ttcatttttt ctttcccgaa
    28741 tcgttgagca atcgctgttc caatcccctt tgagccacca gttactactg cgactttgtt
    28801 ttctaattcc ttgtacatag tacccactcc tttttcatac ctaaacctgt tattacggat
    28861 aacttttatt tccgccttaa agtgagtgta caccaagata tatagtctaa agcaaatgat
    28921 acgctctagc aatcgttttc atgaattgct agtgtccttt tatttctata aagaaagagg
    28981 ttgtgacaga agtggtcagc ttcaagaaat ttcggcttat ttccgaagaa gctacttctg
    29041 aaaaaccatt tatttggaaa aaaaggctgt gacaagactt ttgtcacagc ccctttcctg
    29101 ggcttattta tcacccattt tattgtaatt gctagttata cataaacaag agattttatg
    29161 cataatgttt tattgctgag aaaaatattc agctgttgct tgttcatcct ccttgagttg
    29221 ttcaatcaat tcctctacac tagaaaattt cacttgatct cttaaaaatt gattccagcg
    29281 taccgcgaca tgttcaccat agatatcttg attaaagtcc aaaatataca actctacagt
    29341 cagctcccgt ccttcaccga atgtatcatt atgtccaatt gaacccatgg ctggatacca
    29401 tgtttcccca atttttattt ccgacacata aacaccttct ttaggcaaat gaaccgtgct
    29461 ctttactttg acatttgctg tagggaatcc tagtagtctg cctcgtgcat cgccatggac
    29521 aactacccct tctacctcat atgtgcaacc taatagtttt gctgcttctt ttacttgtcc
    29581 gctgtctagt aatccacgaa tacgggtaga gctgattttt tcaccttgtt cttcttcttt
    29641 agaaactgtg acgattttga atcttccttt ggcatattca ggaaaatgag cgacatctgc
    29701 aatgtctttt ggtccatacg tataatcaaa accggaaaca gcatattttg catgtaaccc
    29761 tacgatgtat tgatcaacaa attcctgcgg tgctaaatga gcaaaagaag aagtaaaatc
    29821 aacttcatat aaataatcta tacccaaagc ggccattttt tcttcttttt gcttaaggct
    29881 agtcaaatat ttcacgctgc taggatcgat ctttttaaag acaatagatg gatgctgatt
    29941 gaaagtcatc aatgctaatt tcaatccttc tttttgtgca atttccatac ctgtctttat
    30001 gactttctgg tgtccgatat gcacgccgtc gaaaaatccc agcactaaaa cgacatcgtc
    30061 ttctggaatt tgttctgatt ggtaaggatg tctgatcttg atgatattca ttcgttattc
    30121 ctcatttctc aatactttac taggttttaa tttgtttttt tctttcgggt ttggctgata
    30181 aatactgaca acttttcctt tataaaacaa agcaatttct tctgacggca tttctgggag
    30241 cgcaaataca gtataatcaa gtctcatacc gttttttact ttctgccata cttcatcagt
    30301 aatatctact cgtttgaacc gttccactcc tttttctatt ggcagcaaac aatcatcgat
    30361 tgtcccattt ttcacagctt gagctacttc ttctaatgtc agagcatcct tctgggacat
    30421 accggcactt gctgttcggg tcagatcaga catgtgcgca gggtaaccaa gtttcttgcc
    30481 tgtatctaca gctaatgtgc ggacataggt tcctttcccg cattctactt cgaagcgcca
    30541 agaaatggtt cctgtcactt cgtctcttgt caattcactt gtccggataa aacggtaaat
    30601 ctgagccttt ctaacaggac gctccactgt ttcattattg cgggcatatt catataaccg
    30661 cttaccgttg acttttaccg ctgagtacat tggtggtatc tgggtgatct caccaataaa
    30721 tgaagccatc acttcatcta tttttttttc agataaagac atatctactg gttttgtttc
    30781 tacccgttct ccggatcgat cttccgtcgt tgtactgaaa cctagagtta tctcgcctac
    30841 atagattttc ccagaatctg tcaaatattc gataactttt gtggcttttc caatacaaat
    30901 gggcaacaca ccgtctacgt ctgggtcaag cgtaccccca tgtccgattt ttttcgtatg
    30961 taagattttt cttaatttga atacgcaatc atgacttgtc attccgcgtt ctttccataa
    31021 aggtaataac ccgtccatgt cttttctcca tttcattttt gatttaactg aattattata
    31081 acacattgca tcaattactg acgaatttga catcataatg aacggttttt atttttcggc
    31141 aataaaaacg taacaaaatt catgctcacg taaatagaaa tcatgttatg cttttttaaa
    31201 ggagggaata gaatggaaga ttttttcttt gcaccatttg attggattta tgggtggctt
    31261 acaggtaaat agtttggttt tcacttccca aaaacgaaaa aaaagactgg ccattcttcc
    31321 agtctttttt ccgttttttt tatttatttt ttcagtttct taatcaatgt aaaaaattct
    31381 attttgcggg atcgatttta tcattttatt ggtcaagatt tttccatttc caatccaata
    31441 cttctggcag atcaatacca ttttcacgaa tatagttttg atgttcttgt aatttctgat
    31501 ccattttttt cgcaaaatct tctgcttgac ttcctttgat ttttaaagct gcgtcttttg
    31561 ccaaatgata acgatcaagt tcatttacta cacgcatgtc aaatggtgtc gtgatatctc
    31621 cattttcttt gtagccatga atcattaaat gatggttatg acgatcaaag aaaatcgtgc
    31681 ggaccaatgt ttcataaccg tggaaagcaa ataagatcgg tttgtctttt gtaaaatatt
    31741 gatcaaattc ttcatcgctc aacccacgcg gatcttgact tggatgacgt aatttcaata
    31801 aatctacgac attgatgaac cgaattttta gttttgggaa ttcttccagc agcaaagtta
    31861 cagctgctaa tgcttctaag ttagattccg ttcctgcagc agcaatgacc aattcaggtt
    31921 cctcctcttt tgctgtcgaa gcccaatcaa tgattttcaa gccttcattc actaagacgg
    31981 ctgcttcttc tgctgagtaa aattgagcac gcggatgttt ggaagagatg atcaaattga
    32041 ttttttctga cgagcggaat gctttatcca tgactgcgag caatgtattt gcatccgcag
    32101 gcagatattc acggatgaac tccgccttct tttctgccaa atgtgtcaat attcctggat
    32161 cttggtggct atatccattg tgatcttgct ggaagactgt tgagcttgca atgagattta
    32221 gcgaaggata atcatttcgc caagaaaggt catgtgattt ccgcatccat ttgaagtgct
    32281 gagtcaacat agagtcaacc actcgcaaga atgattcgta acttgcaaaa aaccatgccg
    32341 tccagtcaga acgtaccctt ctaagaaccc ttcatcttgg tgttccgata attgactgtc
    32401 gatgacgcga ccagatggcg aaagccattc atcattttct ggttcgattt tttccatcca
    32461 ttggcgattt gtcgttttga aaacttgatt caatcggttt gattttgttt catctggtcc
    32521 aaatatacgg aaattttctg gatttttctc aatgatctcg cgaacgaatt taccaagttc
    32581 ggtcatatct tctgctttaa cggagcctgg tttttcaaat tgcaaagtat attttttcca
    32641 atctggcata ataagcggtc ttggatcgat tccaccattg gtgataggat tttttgccat
    32701 tctttggtca ccagtaggcg cgatttctct gatttcttct aaaatacgtc cttgtgcatc
    32761 aaataatttt tctggttcat aggatttcag ccaacggagt aaagcatctg catgatccat
    32821 atgttcttga tctacaggaa tcggtacttg gtgtgctcgg aaggttcctt caattggttc
    32881 cccgtcccat tcttttggac cggtccatcc ttttggtgtg cgtacgatca atactggcca
    32941 ttttggcatc acgacatctg ttgctgtctt caggcgagct tctttttgga tggatttaat
    33001 tttctcgatt gcttgatcca ttttttcagc cataacagga tttaattttt ctgaatcatt
    33061 tccttcaata aagaaaggtt cccagccaag tccgttaaag taatttgcta attctccatc
    33121 tgatttacgt gccaagatcg ttgggttggc tatttttgca ccatttaaat gaaggatcgg
    33181 taaaacagct ccatctatca ctggattgat aaagacattt gagaaccagc ttccagctaa
    33241 aggaccggtt tctgcttcac catcaccaat cacgacagca gagattactt caggattgtc
    33301 taatacagct ccgactgcat gtgaaagaga gtatccaagc tctccgcctt catggataga
    33361 acctggtgtt tctggtgctg catgagaagc aatgcctcca ggaaatgaaa atcgtttgaa
    33421 taatttttgc attcctgtct catcttccgt tacttctgga tagatctctg tgtaacttcc
    33481 atctaaataa gcattcgata ccatgacttg tccgccgtgt cctggccctt caatataaaa
    33541 catgttcaaa tcatatttat tgatgactcg gttcaaatgg acataaataa aattttggcc
    33601 aggaatcgtt ccccaatgac cgattggatg ttttttgaca tcttcgggtt tcagtgtacg
    33661 tctcagtaag gggttatctt taagataaag ttgcccaaca gaaagataat tagcagcacg
    33721 ccaccaagcc gtcattttat caaagtattc tttactagaa taatccatac ataacactcc
    33781 ttttcattat tactcttatt ctagcgcaga tactcccaat tgaaacctaa taagcacttc
    33841 tgttcatttg tttggatttt atatctagcc aaatgaacag gtataaaaaa ccacgaaatt
    33901 tttcctttcg ctgacgtttt ttacattgat ccaaaaaact tgtcgttatc acaatggctg
    33961 ttccgcagtt catttcgctc ctcatcatgc ataatttgct gaatgacgct gggccagtta
    34021 acacattgct ggaaaactgg ggctggatcg agcaattcct ttcctgattg atccgtttta
    34081 tgtaaaagtc tctgttatct ttgtcaatat gtgaattggt atcccagcta ctatgctaat
    34141 ttctacaggg attatccaaa atttggatcg tgaccaaatc gaagcggcgt aatcggaaat
    34201 atcaataact tcaacgtgat ttttctttta actgtcaacg gaccgacaaa ctcaaacttt
    34261 tatggtgcag gttccactga tcttctagtt acttggctat acctgactgt cactaaaata
    34321 gattacaatc tagcttccgt tatcggtatc ttgatcttta tctatatgca aaaatttata
    34381 tactactaga aaaaagaaag tcgaattttt tacttttctt tttctctttt ttggttagct
    34441 gacacgccgc aagactaaag tcatggaact cttaggtaat acgtcttaat gaaaacaaaa
    34501 aaatcccgca acccctgatt tcacaggatt tgcgggagtt tttgattagt ctttgttcaa
    34561 gtcgcgaagc aattcatcga tatggttgcc atagacaact gattcatcaa gttcaaagaa
    34621 caattcaggt gtcttataaa tacttagatt gtgccctaac tctcgacgaa tcaatcctga
    34681 tgctttattc aatccatctt gtgctgtttt cttatctgat gctaagtcag ataaaatgct
    34741 gtaatagatc gttgcttgct gtaagtcccc cgtaactttc acatctgtga tcgttacgtt
    34801 ctccacacga gggtcacgga cctttttgcg caaaatatca ttgacttctt ttaagatttc
    34861 ttgaccgact cggcggtcac ggtagttagc cataatgatt ggcctccttt tatcagtttt
    34921 tagtcatttt tgacttcttc catgataaat ccttcaatta cgtcatctac tttgatgtca
    34981 ttgaattttt caatcattgc accacattca taacccattt tgacttcttt cacgtcatct
    35041 ttgaatcgtt tcagacttgc aagttggcct tcatagatta cgattccgtc acggattaca
    35101 cggacaccgc tatctctacg aatatatcct tctgttacat aggcacctgc aatcgtacca
    35161 actttagaaa ctttgaaggt ttcacgaacg atcatttgac cggtgatttt ttcttcaaat
    35221 tcagggtcta gcatcccttt catcgcagtt tcgatttctt cgatggcttt atagatgata
    35281 cggtgaagac gaatatcgac ttcttcagta tcagcttgca cttttgcctg cggtgtagga
    35341 cgaacgttga aaccgatgat aatagcgttg ctggctgctg ctaaggttac atcactttca
    35401 ttgattgctc cgacagctga atggacgatt tttacacgga caccttccac atcaatcttc
    35461 ttcaatgatg cagccagtgc ttctgctgaa ccttgtacat ctgctttgat gattacgtta
    35521 acttctttca attcgccttc tttcaggctt tcaaataagt tatccaaagt cacacggctt
    35581 gtggcagcac ggttttctaa taatgcacgt ttcgcgcgtt cttcacccgc tgcacgtgct
    35641 gtcttttcgt cttcgaagac tacgaaacgg tcacctgctt gaggtacatc attcaagcca
    35701 gtgatttcta ctggcgttgc aggtcctgct tctttatcgc gacggccaag atcgtttgtc
    35761 attacacgga cacgtccgta agtattaccg acaacgattg ggtcaccaac atgaagtgtt
    35821 ccttcttgga caagtaaggt tgacacagga cctttacctt tatcaagacg tgcttcgatc
    35881 actgttccga ttgcgcgttg tgttggatct gcttttaaat cttctacttc tgcgactaac
    35941 aggatcattt ccagcaattc ttcgatgttt tggccgaatt tcgctgagat ctcaacaaag
    36001 atcgtttctc caccccatgc ttcaggaatt aactcatact cacttaattc ttgcataaca
    36061 tgttgagggt ttgcacctgg tttatcaatt ttatttacag cgacgatgat tggaacgcct
    36121 gcagctttgg catggttgat tgcttcaact gtttgtggca tgacgccatc atctgcagca
    36181 acaactaaga tcgtgatatc tgtgatactt gctccacgtg cacgcatact tgtaaaggcc
    36241 gcatgtcctg gtgtatccaa gaaagtgatt ggtttaccat caatatcgat ctggtaggca
    36301 ccgatatgct gtgtgattcc gccggcttcg ccgcttgtta cacgtgaatg gcgtaatgta
    36361 tccaataaag ttgttttccc atggtctacg tgtcccataa tcgttacgac tggcggacgt
    36421 gagactaatt tatctggatc gacttcttct gcctcgaaga atttatcgat atcagcaatg
    36481 tcaacttgga ctttttcttg tggttccatg ccatagtccg tcgctaacag ttcaatcgta
    36541 tctttatcca gtgcttggtt ttgattgacc atgacaccaa gcataaataa ttttttaatg
    36601 atttctgctg gctcacgatg aatttttttc gcaatatctg ctacgttcat accttcagta
    36661 tactctaata catctggcaa ttcacggaat ttgcgtggtg gtacagctgg tttagttgat
    36721 tgttgctgtt tgcctttttt acctttttta ttataacgat tacggttatt attattaaat
    36781 ttgccgcgat tgttattgtt tggtttgttg ttattgttag tacggttttg attgccgcct
    36841 tggctcgttc cttgacgatt ttggctgctg gtatttcccg tattattttg gtttgttgtt
    36901 ggtttttttc cttgattcac ttgaccgctc ccttgaccgc gatcttgata actgcggtta
    36961 tttttatttt tttgttgatt gttcgttgtt tcttttttac gttgatcgtt cggctgttga
    37021 ttggctggtt ttctgcttgc ttgttgtgca gcttgttgtt tcgtgcttgg gtttttgaac
    37081 gcttgttgca atttcttctc atcattgcta gtaatcgcac ccatatggtt tttcacatcg
    37141 atgccaagtt gttgtgcttt ttccacgacg tctttactag attttttgag ttcttttgct
    37201 aattcataga ttcttttgtt gcccatgcaa tcaccttcct aaccttcaat tagctccttg
    37261 gtcttcttcg caaatccggc atccattatt ccgaatacct tgcgaggttt tccgatcatc
    37321 tgcgtgattt ctgcttcaga aaatagctca aagcaaggaa cttcataata tgaactctta
    37381 tcttttatct tttttcttgt attctcgctt gcatcggttg ccacaaacac caattttgct
    37441 ttttgtttgc ggatttcagc aatggtcagt tcttcacccg tgattagttt tcccgcgcgc
    37501 atcgctagac cgatgagatt catggctttt tgccgattaa ctgtattcat tttccaaata
    37561 actctttacg tgctttttgg tgagtgacat agtcaagaag ttcttgataa aactcatctg
    37621 ttaatgttgt ttcgagtact cgatcgagaa tttttttatc ccaagcttgt tgtacttctt
    37681 ccggctcaag tgagacatac gctcctcgtc caggcatttt tccagttgga tcgatcgata
    37741 cttccccttc ttttgaacgg gtgattcgga ccatctcttt tttaggtttc atttcacctg
    37801 aaaccacgga tttgcgtaaa ggaattttcc tttgtttcat ctctttgcct ccttactaaa
    37861 gttaagcttc tggtttttct tcgaccgttt cattgttgaa tgcaattgtt tcatattcat
    37921 cgtctgttaa atctgactga acgattgctt catcatgcag ttcttctgtt tctttttgtt
    37981 gttcttgatt ttcataaaat tccgtcatgt cagattctga tttgatatcg attttatggt
    38041 tagtcaattt agcagctaaa cgtgcgtttt gtccgcgttt accgattgct agcgataatt
    38101 ggtagtctgg aacgacaact gtgcaggcct ttggatttgt ctcatcgaag atcacatcca
    38161 tgacttgtgc aggattcaat gcatttgcaa tgaatacagc tggatcttca ttccattcga
    38221 cgatatccat gttttcgcct tttaattcat tgacgattgc ttgaactcgt tgtccctttg
    38281 gcccgacaca tgtaccgact gcatcgatat ttggatcatt tgagcgaact gccacttttg
    38341 aacgatcgcc agcttcacgg gcgatgctga caatttcaac gattccatca tagacttctg
    38401 gtacttcttg ctcaaataag cggcgcaata ggtctggatg gctgcggcta acaaatactt
    38461 gcggaccttt agacgtattt tctactcggg aaacataaac tttgattcga tcatgtggtt
    38521 gataaaattc atttggcatt tgatcttgtt tagaaagaac tgcctcaatt ttaccaagat
    38581 tgacataaat ataacgttta tcctggcgtt cgacgattcc ttgcatgatg tctttttcat
    38641 aagcactgaa ttcgttataa ataatcgttc tttctgcttc acgtacacgc tgtaaaataa
    38701 cttgtttagc cgtttgcgca gcgatccgcc caaaatcttt tggtgttact tcaaaacgga
    38761 tcgtatcacc gatctcatat gctggattga ttaaaagtgc atctttcaat gagacttcca
    38821 actgtgaatc catcacttct tccgttactt cttttaccgc atagacatgg atctttcctt
    38881 ttttctgatc aaattccact tcgacgtttt gtgcttggcc atagtgacgt ttgtatgcag
    38941 aaaccaatgc tgcttctaaa gcatcgatca cgatttcttt tgagatccct ttttcagctt
    39001 ctaaagcgtc taacgcattt aacatttctt tactcatttt ttctgattcc tctccgtgat
    39061 taaaattgga tagctaagcg agcttttgca atattttttc ggtcaaaagt caattctttt
    39121 tctcgtgttt ttatgcgtat tttcaatgta agctgttcag catcaaatga ttgaagaaat
    39181 ccttcatatt gtttttcgcc atctactggt tggtataagg agacatggac ataatcacca
    39241 agtgcctttt catagtcgct ttcttttttc aatggccgct ctgctcccgg ggaggatacc
    39301 tccaggaaat aagcttgagg aatcggatct ggatctgctg catcaagttt ttcactcagt
    39361 ttctcactga caaaggcgca ttcttcgata tcgataccgc cttctttgtc aataaatact
    39421 cgtaagaacc agctttttcc ttcttttaca aattcgactt cgacaagttc aaaattttgt
    39481 tcatctaaaa tcggtgtcac catttctgtg actgtttcaa cgacgctact caaaagtttc
    39541 gcctccttaa aaaattaagt gcgtaattcc attaaaaaga gtgagcgaaa aatccgctca
    39601 ctcacagtta gtatcattac ctataagaac tataccatac tctgcttaaa attacaagca
    39661 gacaggaaaa cagatgctta tagcatatcg aataacgata attgattttc atctggtaga
    39721 tctttcaata cgccattgtc gttcatatat tcgatcaatg tttttgaaac tttaccgcgg
    39781 gtggcaagat cttctttgga taaaaatgga ccgtcttttc ttgcttcaac gatttgtttt
    39841 gccacgttgg ttcccaaact tgggacagct ctaaatggtg cgatcaacgt atcaccttca
    39901 ataacaaagt taacggcatc cgatttatac aaatcaatca ttccaaattt gaatcctcgt
    39961 tccagcattt cattggctaa ctccagcact gtcagttgat tcttttcttt tacggaagca
    40021 tctaatcctt tgtccgtgat ttctttcatt gcttgtttca cagcatcttt tcctttgcac
    40081 atggagacta gatcaaagtc gtctgcacgt acagaaaagt atgcacagta atacaaaata
    40141 gggaaataaa ccttgaaata agcgacacga agagccatca atacgtaagc tgcagcatgg
    40201 gctttcggaa acatatattt gatttttgaa caagaatcga tataccagtc gggcacatta
    40261 ttttctttca tcgccgatag ataggtttct cgcaattcat cagggatctt gttccattgt
    40321 cctttacgaa cagtttccat gattttaaat gccatcccgc tatctaatcc agcatggatc
    40381 aaataaacca taatatcatc acgacagccg attacttccg ccagtgtcgc atctcctcgt
    40441 cgaatcaatt cttccgcatt tcctaaccat acgtctgtac catgagatag tccggaaatt
    40501 tgcagtagtt ctgcaaaagt tgtaggatgc gtttcttcta gcatccctcg aacaaaacga
    40561 gtgccgaatt ctggaatacc taatgtccct gttttggaat aaatttgttc ctgacttact
    40621 ccaagtactt caggaccggc aaatatccgc atcacttccg ggtcatccgt agggatcgtt
    40681 tgtggatcga tccctgataa atcttgaagc atccgaataa cagttgggtc atcatgccct
    40741 agaatatcta atttcaatac attatcgtga atcgagtgaa aatcaaaatg agtcgttttc
    40801 cattccgaat tttgatcgtc tgctggatat tggatcggcg taaaatcata gacatccata
    40861 taatcgggaa taacgatgat cccccctgga tgctggccgg ttgtccgttt gactccagta
    40921 gcgccttttg ctaatctgtc gacttctgca cttcgaaact gcagattatt gtccctttcg
    40981 tatcctttta catagccata tgctgttttg tcggcgactg taccaatcgt tccggcacgg
    41041 taaacatagt cttcgccaaa caatactttc gtatagttat gggcttctgc ttgataatca
    41101 cctgagaagt tcaaatcaat atcgggcact ttgtctccat ggaatcctaa aaatgtctca
    41161 aatggaatat catgaccgtc tttgtttaag cgtgcaccac attttggaca ttgtttttct
    41221 ggcatgtcaa atccagaacc atacgtacca tcttcaaaaa actcggaata ttggcactct
    41281 ggacaataat aatgaggggc taacggatta acttcagtga ttcctgtcat cgtcgcaaca
    41341 aagctagagc caacagagcc acgtgaacct actagatagc catcttcatt acttttatgc
    41401 actagttttt gggcgatcag ataaataacc gagaagccat taccattaat agaattcaac
    41461 tcttttttta atcgtttttg aatgatctca ggtaacggat ctccgtacat ttgttttgct
    41521 tttgtgtaac tcaattctga tatttcatct tctgaacctg gaatcttcgg tgtataaagt
    41581 tcatctttga ctggaatcac ttcttcgcag atatctgcga ttttattcgt attttctact
    41641 acgatctctt tcgctgtttc ttcccctaaa aagtgaaatg cagttagcat ctcatcggtt
    41701 gttcggaaat ggacatccgg caaactatga cgattcaacg gattcgctcc gcccatagaa
    41761 ttgatcaaaa tttttcggta aatggcatct tcttcgttca gataatgtac attacctgtt
    41821 gcaacaacga ttttatccaa actttttccg atttctacca aattttggat aatttcttcc
    41881 aaatcatgtt cattttttac caattcttgc tcgatcaaag gcgcatagac cgcttttggc
    41941 ataacttcaa tataatcgta gaattttgct cggtttcttg cctcttctac ccctttttgc
    42001 atcatggctt cgaatatttc tcccttatca caagctgagc cgatcaatag attttcacgc
    42061 atctttttca attgggagcg tggtattcgt gggacgcgtt cgaagtattc gacattcgac
    42121 attgaaatca gtttgaacaa atctttcagt cctgcctgat tttttgctaa aatcgttaca
    42181 tggaaaggtc gagccctttt gtaagaatct ccttctccga tatgctcatt tagctgatca
    42241 tgataaagca tgttatgatt gtccattgcc tctttcacaa agatccatgc taagtgacca
    42301 gttgcttcag catcatagat tgctcggtga tgctgttcca agctgacacc aaatttttta
    42361 gataacacac ctaatccgaa acgtttgaat tgaggataca gatatctagc taattccaac
    42421 gtatcaatga ctggattggc cgcttcagga ataccatacc ttgcgtagct agtattcaag
    42481 aaccccatat caaaagccgc gttgtgggct accaaaattg tatcttttga aaattcaagg
    42541 aacatccgca atacttcttc ttccgacttt gatcctcgaa ccattccatc cgtgatacca
    42601 gtcagatcta ccgttgttcg tgacaaagga tgtcctggat cgataaattc atcaaagctt
    42661 tcgatcacat ttcctttata cattttgact gcggctagct cgatgatcgt gtcatatact
    42721 gcagacaatc ctgtcgtttc cacgtcaaat acgacatatg tggcttcact caatgcttca
    42781 tgtgcatcat tataagcaat tgggacacca tcatctacga cattcgcttc cacgccgtat
    42841 aagattttca cacctgcttt ttttccagca ctatgtgctt ccggaaaggc ttgcgcacca
    42901 ccgtggtctg taatggcgat agctcggtgt ccccatttcc ctgcttgtgc cacaagatca
    42961 gagatgctgt ttgttgcatc catcgtactc atattgctat gaacatgaag ctctactcgt
    43021 ttttcccctt caggagcata atctttgcga ggtgtatgtt tgacttctat gatatcttgc
    43081 gcattcatga ccaaatcacg gacaaacgta tcttcttgaa tacttcctcg tacctttaac
    43141 cagctaccga cactgatcgc atcaaatact tgttcatctt tttcgccgtt cgagaatttt
    43201 ttgacgataa atgatgaagt ataatctgtg attttcaaag tcaagatctt gcgttttgaa
    43261 cgtagttctc tgacttcttt gtcgaatacg tacccctcaa gtgtgactct tcgttcttct
    43321 tcaacgatac tgatcattgg tgtcgttggt tcatcggctg gaatatttcg tcctagctgg
    43381 atgtggatgg gtccttcaag agctggcgat tgctcttttc tttccttttt cttttgttcg
    43441 tggacaacta gactttcagc tgcttgcttc ataaaggctt ctgcctgttc ttgtttgcgt
    43501 tcttcaaaaa gtttcaatac tcgttccgct tgctgctcat ccacttctgg ttcgatacga
    43561 aattttggga atccgtaact gacgaacaac tcttctacta atggcaagta ttgttgcttc
    43621 aaataagaaa tagctcctgt actgtcgatt ggcaagatga ctttacgatc ttttatcaca
    43681 ggtacctgcg ttttcaatac ttgctgtgct agtggtgtat cgcattgctg attttccaaa
    43741 gcttgggccc agtaatcttg caagagctgt tcatcgaatg tctggtcatc tgctaagata
    43801 ttcagtttga cttgtgcaat atctttaaaa gcgatagtca gatgctgagt caatgaccga
    43861 tatagcataa taggcaaaat tttggaaaaa tgcagcgtaa attcccataa acgcgattta
    43921 cgatggacca ctacactatc catttcacca gcagtaagca gtggatgatt tttttctgct
    43981 tcctctagtt ggatttgttc caacagtttt tcaaataaat ctcgtttttc tgacaaagat
    44041 atacgccctt tctgatgaga aacaatgcaa ttgatcgcat cttatcctct tctttttcag
    44101 taccttttag tatactcgtt ttttctgagt tttacattaa aaaattggaa ctgcgattca
    44161 aatcgcagtt ccaattttaa aagcgaatca tcagattgtc aaaaacagct gattcagcta
    44221 tttttatttt ctgtgtttta acgcttatta ttcgccttgg ttcaagagga ttggtaaagt
    44281 attcaccaat tcttctttac gtacttcaac catttcgcca gttttcttga ttttcacttc
    44341 tacgattcca tccactgctt ttttaccgac agtgattctg attggacagc caatcaaatc
    44401 agaatccgcg aatttcactc ctgcgcgttc atttctgtca tcaaccagta cttcatagcc
    44461 agcttttgtc atcgcttctt ctagttcatt cgtcaggttt gtttggtatt cgtcttttag
    44521 attcatttgg acgatatgca aatcaaatgg cgcaattcct tttggccagt tgattccttg
    44581 ttcatctgaa tgttgttcta cgattgctga taataaacga cttacaccga taccataaca
    44641 gcccataatc acaaattttt ctcgtccatt ttcgtctagt acagttgctc ccatagattc
    44701 actgtaacga gtgccgattt tgaagatatg tccgatttcg attcctcgag taaaggcaag
    44761 aacaccattg ttgtctggtg aaggatctcc ttcttgtaca aaacgaagat cttcataaga
    44821 aagtacagtg aaatcgcgtt ctggattcac atttttatag tggaatcctg tttcgttcgc
    44881 tccagtaatg gcattcgcta aatcttggac ataacggtct gcatatactt ttacgtcatc
    44941 tgaaacaccg actggtccga cagaaccaaa ctcagcacct agatattttt gtgcttcttc
    45001 ttctgttgct tcttctaaaa agtcagcaga taaaaagttt ttcagtttta cgtcattgac
    45061 ttcatggtct ccgcgtacca aaacaaggac aggttgttca tccgcaatga acaatacaga
    45121 cttgatgatt ttttgaggtt caacagaaaa gaaatctgct acttcgtcaa ttgattttac
    45181 gttaggtgta gctactttct ccaattcaag ctgtgtttca tgcgattttt ttgatacata
    45241 gtagcttgta gccatctcca agtttgcagc ataatcactt tcagtcgaat aacagatcgt
    45301 atcctccccg atttctgaga tcgccatgaa ttcttttgag tctttcccgc ccattgcgcc
    45361 accgtctccg ataatcgagc gaaattctaa gccacaacgc ttgaatactt cggtgtaggc
    45421 tttttcgtaa tctttatatg tctcgtccaa actttcttcc gttgcatgga aagaatacgc
    45481 atctttcatg ataaactctc ttccgcgaag caaaccgaag cgaggtcgtt tttcgtcacg
    45541 atatttaggt tggatttgat aaagatttaa aggtaatttc ttatatgaat tgatttcatt
    45601 acgcatcaaa tcagtaaaag tttcttcgtg agttggtcca aggatcattt ttcgatcatt
    45661 gcggtctttg aaacgataca agtttggtcc atatgtttcg taacgcccgg attcttccca
    45721 aagttctgct ggcaagatgg caggcatcag catttctacc gctccgattt tttcaaattc
    45781 ttcccgcata atgcgtttca gtttttccaa tacacgattt gctaatggca gatatgaata
    45841 aatacccgct gatacttggc ggatatatcc agctcttagc aagatttgat ggcttaatac
    45901 ttctgcatca tttggaactt cgcgtaatgt tggaatcaac atttttgatt gtctcattct
    45961 atatactcct ttatttcctc aaaatagtta tcgtttgtta ttatacccta tttgtcaact
    46021 ttttctagaa aaagaatcgt tgaatatcgt tccatgtaac tagcaccatc aacaacatta
    46081 aaaatccaaa gccagctaat gtcaatattc cttctttttc ttgacttaat ggtttcccgc
    46141 gaatcccttc aaaaatattc aagactaatt tcccgccatc taaggcagga atcggaagca
    46201 gattgacgat tccgagattc attgaaagaa gcgccatcaa actaataaca gttgttacac
    46261 cttgatttgc tgcttctgaa gacaattggt acatcatgac aggtccgcct aatttatcta
    46321 aactgaaacc tgtaaatagt gatcctaagg ctttgaaaat ttccaatgaa ccgctgaaag
    46381 cttgacgcgt ccctccaatg atcttatcca taaaacctgt attcattggg gcttttatac
    46441 caagttggcc aactttttcg ccatttgact ctacagattt cggtgtcacg tcgacagatt
    46501 gcacctgacc ttctcgttcg atcttaaagt ctaatgtttt atccggattt ttcgtaatga
    46561 ctgttgtcag atcattccat gaatggattt cttttccgtc cacactgact acctcatcat
    46621 tttcttttaa gcctgcttct gccgcagctc cattaggcat gatctctcct acgcgattag
    46681 tgttcgtcac ttgaacacca ccttgcataa atgccagaat gatgaataac aggattgcca
    46741 aaataaagtt attcatgggt ccagcaaagt tggtcagcat acgctgccac aatttagccg
    46801 attggaactg tacgtctttt ggcgcaattc tgatttctgt tccgtcgttt tcaataatcg
    46861 tcgcatcgtg atcaacaggg taggttacta cttctgtttc gtctccattc acataaccag
    46921 tgatagtcag ctcatcttct aaatcataac ggctcaattc catcgggata gcatttgtca
    46981 attggatttt cttacttaaa tttatcttct ctacgatgcc gtcagaattt agtaaaagag
    47041 aaagaggcat tcctggtgcc atttctgttt catcatcccc attgcctgcc attcgaacat
    47101 aaccgccaat aggtaatagg cgaagcgtat atgttgtccc gtcttttgct tgatgcccat
    47161 aaattttcgg acccataccg atagcaaatt cgcgaacgag gattcctgat cgtttcgcaa
    47221 agaagaaatg accaaactca tgaacaatca ctaatatacc aaaaacgatg ataaatgtca
    47281 gaatcgtttt catagctttt ttctccttta cttgtttttt gtgtttttta taaaacaacg
    47341 ataaaacact ataattttac catagtatac caaagacacc aatagtatca atataatgaa
    47401 aaataaaaac ctgcgtcttt tatgaaattc acaaagaaac gcaggtatac ttactaaata
    47461 atgccaaata aatgcatgat aggaaataca aacagcaaac tgtcgaaacg gtctaagatt
    47521 ccaccatggc ctggtaagat atttcccgag tctttcacat cataatgacg tttgattgca
    47581 gattcgacca aatcaccaaa ttgtccgact gctgaaaaaa taatcgtcat cagaagcatg
    47641 acaaacatac catgattaaa tagttctttt gctgggtata gcaataaata aagaaatgcg
    47701 actacaacag cactaccaat accaccgagc gcaccttcaa tcgttttgtt gggcgaaata
    47761 tcaggactta acttatgctg accataacgt cgaccaacca tatatgctcc gatatcagtt
    47821 gcccaaacaa taaatagacc aaatatcaaa acagccaagc tttctgttcg tgcattgaca
    47881 aaattctgga aacctattcc cacatacaag ctgacaagca caggaaaacc tgcttcatca
    47941 atcgtatacg tatttttaga aataactgat gttcctaaaa gaatcataac tataagataa
    48001 aataacataa atgtacttac attctctgga agaaagaaaa accatctttc ttttggcaaa
    48061 acaagtaaca ctgcaccaac ggcggataaa actccttcaa aacttaagag tgtcaatcct
    48121 ttcatccgaa acagctcgta aactcctatt actgctaaga ttgctgctgt aagctcaacc
    48181 gctatgcctc cgatccatat aatcggaata aacaagacta gcgccacggc tgctgtgacc
    48241 acacgttgtt tcatgactga tcccctttct catcttctgt tttttttaca ccgccgaatc
    48301 gacggtctcg attttgataa gaggcgattg cttcttcaag atgcgcacca tcaaaatcag
    48361 gccaaagcgc ttttgtaaaa tacagctcac tatatgcgat ctgccataac agaaaattac
    48421 taattcgctc ttctccactt gtacggatca tcagctcagg atcttgtaac tctttaggca
    48481 agaaacctgt cattaaatgc ttagcaatca attcatcatc gatttcttct gcgtgtattt
    48541 ctccttttgc tacttcttcg gcaatttctt ggacagcagt cacgatctct gctctgcttc
    48601 cataattcaa agcaaaattc aataccattc cagtattgtt ttttgtttgc tcaattgcac
    48661 gtcttacagc atcttgcgta tgttctggca atacgttttc ataacccatg acatgaactt
    48721 tgacattttc tttaatcaat tctggtacga acgtatcaaa gaagtcgaca ggtagttgca
    48781 tgagaaaact tacttcatct tttggtcgct tccagttttc agtcgaaaag gcataaagcg
    48841 tcaacacttt cactccaagc cttgatgctt tttttgtgac tttctttact gtttccatgc
    48901 cttctttatg gccagcaact cgtggcaaac gacggttttg cgcccaacga ccattgccgt
    48961 ccatgatgat ggcaatgtgc tgaggaattg gtccatcggt attaaattga aattcgcttt
    49021 tttcttgaat atatttgttt ttttgcggaa aaaaacgtaa cattcttttt cctcctatac
    49081 ttaaaagatt cccactatct taagtattat agcaatatct aactgttttt cctatgaaat
    49141 cattgttttt ttatttaaaa actgaataat tttttctttt tttaattttt aaataaaaga
    49201 aatataaata aaaacagagg aagcggaatg atccgcccct ctgtttttat gattttatta
    49261 aacttccaat aattcttttt ctttatcagc agcgatctta tctacttctt tgatgctgtt
    49321 atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg taatatcacc
    49381 atttttttgt tgttttttat attcatcgat cgcatcacga cggatgttac gaatcgcgat
    49441 ttttgcattt tctgcttctt ttttaacatc tttagctaat tcttttctgc gttcttctgt
    49501 cagttgcggg ataactaagc gaatgacatt tccatcattg gttggactga ttccgatatc
    49561 acttgccata atagcttttt caacatcttg aagaatgctc ttgtcaaaag gtgtgatcat
    49621 taaaacacgt gcttctggaa tttggattga tgccatttgg ttcaatggtg ttggcgcacc
    49681 gtagtagttc acagtaatac ggtccaaaag gctagcgttc gcacggcctg cgcggatttg
    49741 cccaagttca cgttgaagat tttgtgctgc ttttttcatt ttttcttttg cttctgtcat
    49801 aattgcatct gccattttta tttccccctt acagttgttc cgatattttc gcctaagatt
    49861 gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat atcattatcc
    49921 atgcttagtg aacttgcagt tgaatccatg acttgtaatc ctttggcaat aacttccaga
    49981 tgagtcagtt cttcaaattt tactgcattt gcatctactt tcggatcagc agaataaaca
    50041 ccgtctacat tgtttttagc catcaggata acatctgcgc cgatttctgc cgcgcgtaat
    50101 gctgctgttg tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa gataacgatc
    50161 cgtccttttt ctaaatgacg ttctgcttta cggcgaatat atggctctgc gatttgacgc
    50221 atttcaatcg aagtttgcac gcgtgtcggt acacccacgt tttccaacgt atcctgtaaa
    50281 gctaaggcat tcataactgt agctaacata cccatgtaat cagcttgagc acgttccatg
    50341 cccatttgtg ctccgatttg tccgcgccag atatttccgc cgcccacaac gattgccatt
    50401 tcaacgccca gctcgtgaac ttctttgatt tcttggatga tttctttgat tactggtggt
    50461 ttgattccaa atcctgcgtc cccagctaaa gcttctccac tcaattttaa gactacacgc
    50521 tgatatttcg gtgtgaccat gttcattcct ccaatatttt ctattgccat tttaccatac
    50581 ttagatgatt tcgacactct aagactggtt tttcttgttt tgcttaaaaa aagggagcgc
    50641 acaaaccgtg cgttcccgtc tgttattcaa cagaattatt ttttcacttg gctcataact
    50701 tcttctacaa agttatcttc gcgtttttcg ataccttcgc caacttcgaa acgtacgaat
    50761 gttttaacag ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc aggatcttta
    50821 acgaatggtt ggtccaccaa agcgatttct gctttgaatt tcttcaagcg tccttctacc
    50881 attttttcaa cgatattcgc tggtttgcct tcgttcaatg cttgttctgt aagaacagtt
    50941 ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt ttacataacg aggattgata
    51001 gctgctacgt gcatagctac gtctcttgca actgtttcgt cagttgttcc atctagaaca
    51061 gtcaatacgg caatacgtcc gcccatatgc aagtatccac caaatgcagc attgtcgtct
    51121 ttttctacaa cttcaaagcg acggaagctg attttttctc cgataacttg agttgcttcg
    51181 atcaagtcag attcaattgt acctttatct gttttgattt tcattgcagc ttccatgtct
    51241 gctggtttgt tttcagcaac aagttctgca atttctttta ctaaatcttg gaacatttcg
    51301 tttttagaaa caaagtctgt ttctgagttt acttcaacga ttgctgcagt gttacctttc
    51361 acagcaactg aagccaatcc ttcagctgca atgcggtcat ttttcttcgc agcctttgcc
    51421 attccttttt cacgtaaaag atcaactgct ttttccatgt cgccttctac ttcaactaat
    51481 gcttttttcg catccatcat tcctacgcca gtcatttcgc gtagttcttt taccatttta
    51541 gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa aaaagctgct
    51601 tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt caaaattatt
    51661 ctgctgaaga attgtcgcct tcaacaacat ctacgatttc ttcgattgat gttgctgtgt
    51721 tttcttctgt gaaatcttct tcaactactt gatcttcacc ttggtttcct tcgatgaaag
    51781 catcagccat ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg tttgaaggga
    51841 ttactacgtc gatttcatct ggatcgcagt ttgtatcaac catagctacg attgggatat
    51901 ttaatttgtg tgcttcttga acagcaatac gttctttacg tgggtcaacg atgtacatta
    51961 catctgggat tcttggcata tcagcgatac cgcctaagaa tttttcaaga cgttcacgtt
    52021 ctttgttcaa accagcaact tcttttttag gtagaacttc aaaagttcca tcttcttcca
    52081 ttgcattgat ttgtttcaaa cggctgatac gtttttggat agtatcccag tttgtcaatg
    52141 ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc acgagttgct tcttctttga
    52201 ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc tacgccgcct tcttcagcaa
    52261 cgctcttcat gtaatcataa gctgcatcta ctaatttaac tgttttttgc aagtcaatga
    52321 tgtagattcc gtttctttct gtgaagatat atttcttcat ttttggattc cagcgacgag
    52381 tttggtgacc aaagtgtacg ccggcttcta gtaattgttt catagaaatt actgccatgt
    52441 ttgtttcctc cgatttggtt ttatttttcc tcttcttatc ttctaccttg ccggcaaact
    52501 ttttcaagca cctaccgaca atccaataag aatgtggatt tgctgatgca taaagcaccc
    52561 tcagctatta tacagacaaa agatccgtat cgcaagagca aatatacttt tctgctcaac
    52621 attcaatagt ttacctgaaa gataaaaaga attcaagaaa aacagtagat ttctctttgt
    52681 ttctttatta tcctttttcc ataaaataat tttaggtata aaagacgaat attattgggc
    52741 aatccttctt ttttttgtta tgatacatgt gaaatctttc gtaaaggaga aagaaaatgc
    52801 gcaaagctca aagacatttg ctgattaaac aagtcattga agaattcccg atccgtacgc
    52861 aagaagaact attaaacaaa cttgggcatt atggcgttac cgccacgcag gcaacgattt
    52921 ctcgagatat ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc gtttcccgct
    52981 tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac tgaggaagag gatcggctgg
    53041 ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt ccactttttg acgatcgtca
    53101 ataccttgcc agacaatgct catttatttg catctgtttt agatgagatc aaacctccct
    53161 ctattgtcag tacaattgct ggattcgata cgatcatggt catctcggaa aatgaggagg
    53221 acgcaaaacg agtagaagaa tttcttcacc atccaactga agtatcactt ttttaatcag
    53281 agcacgtatt cctaatatgg aatgcgtgtt tttttatttt caatattttc cttattgaat
    53341 aaacctttac actctttaca aaaatacatc attttttatt caaatttttc aacaccttga
    53401 ttgaatcaca ataatcatca tttatattgg atgttaacaa gagcagcttc ttgctctttg
    53461 tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa attattaact tctggaccat
    53521 tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga tcattgtact tgggatcaag
    53581 aatacaaaga aattacacaa tggataagaa aaaaattatt ggatcttgct caagtatcgg
    53641 aaggaatata cacaacggtc ttaatgcaag gtagcagctc cttcggggta gaatcggtat
    53701 taagttctgt gatcaggcca gaagatactg tactgatttg ttcaaacggc gcatatagac
    53761 aacgaatgat caacatgtgc gaatgtctga aactgaacta taccgtttat gaggtatcgg
    53821 aacatcaaat cctccaagct catgtgatta cacagctgat tgaagagaat ccgtctatct
    53881 ccgcactagc aatggtccat agcgagacta cttccggtat tttgaataat ttggaagaga
    53941 ttgctgctgt cacacaagaa agagatcttt tgtttatagt ggacgcgatg tcaagctttg
    54001 gtgggatacc gatttgtgta gccgaactag ggattgattt tttgatttcc agctcaaaca
    54061 aatgtattca aggtgttcca ggcttttctt ttgtacttgc taataaagcg gaactggaaa
    54121 aacgaaaaaa tgttagccga agtttgtcac ttgatctata tgaccagtac cgcgtgatgg
    54181 aaaacgagaa tggcaaatgg cgtttcactt cccctaccca tacggttttg gcttttcaac
    54241 aagcgctgaa ggaactagag gcagaaggag gaatcgaaac tcgatattca cgttatctcg
    54301 ccaataatca tgtgctacga caaaaaatga cagagatggg gttccagcct ttcattcaag
    54361 aatatcaggg gccattcatc acctcttttc tttaccctaa ggactggcga tttgatttta
    54421 atcattttta tcagtattta aagcaaaatg gatttgtgat ctatcccggg aaaatcagcg
    54481 atcatgaatg ttttcgtatc ggaaatattg gcgagatcta tccggaagat attttggaac
    54541 tgacagcaat tatcaaagac tataaggaga acgttaatga ttaaaactgt aatttttgat
    54601 tgggcaggaa caactgtgga ctttggctgt atggctcctg tccacgcttt tagaaatgct
    54661 tttctagaaa aaggaatcca actgactgac aaagaaatcc gctaaccgat gggaaaatta
    54721 aaatgggatc atatccaaca gcttctttcc ctcccttctg tcaaaaaaca atggatagct
    54781 atttatggac aactacctca ggaaaaagag gtggaggaat tgtatcaaca atttgaacat
    54841 tatctgttta aagatttggt caagcattct accttgaaac ccgacacatt ggaaacgatc
    54901 gaacggttga gaaacgctgg gatcaatatt ggttccacga atggatttaa tgctcctatg
    54961 atgacaatcg tagcagaaac cgcaaaaaaa gaaaggtatt caccagactt catggcaact
    55021 tttgaagacg tcgaagggta tggtcgaccg tttccttata tgatccataa aaacatgcag
    55081 tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg gagatacggt ctcagatatc
    55141 caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag ttcgctaatg
    55201 gggatttctt atgatgagta ccaaaaatta gagatgggga aaaagatcgt ttaaaacagt
    55261 ctgttgctct tagattccaa caagccggcg ctgatatttg tgtaaacaat ttaaaagagt
    55321 taacagaata cattttgtac gctgacatga atccagaatg acttttatac aaaataagag
    55381 gttgtgaaaa agctgtcctg tatcaagtaa taaaaacagc caagcaaaaa tagctcctca
    55441 tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac cgtttattcg
    55501 aaaaaaaaaa gggagctgtg acacgacttt tgtcacagtc cccttatttg caaacaaaca
    55561 gtgtttaaga gacaacctct ccactaaacg gtgttcattc agctgactct cggtatttgc
    55621 tcaaaaaacg ataaaatttg aaaagctatt ttctcttttg tttctctaat actcggatca
    55681 gaacgctgat ttcacattct ctttttctta catcttatct ggtgcatgaa gtcctagcaa
    55741 acgaaggtct tctttcaata atacagtcac tgcataaact agagctaagc gtgcttcttt
    55801 ttgttcatca tcagctaaaa tcttcgtatg agcatagtat ttgttgaatg cttgtgctaa
    55861 tttgattgca tgtttcgcaa tcactgacgg ttcgtatttt tccccagcag acaagaccgt
    55921 ttcagggtat ttttgaacta atttaaccac ttcccagctg gtatcgtcat tcaatgcata
    55981 gtctgctgtt tctgaaggga caaatcctgc tttttccaac aggctgactg cacgagcatg
    56041 tgtatattgc acataaggtc cagtttctcc ttcaaatcga acaacttctt ccaggttaaa
    56101 gtcaaatgta ttcagtcgat cgtttttcaa atcgtggaaa atgactgccc caaccccaac
    56161 ttgtttagct acagcatctt tgttttccaa atcagggttt ttctcgctga tttgttcttt
    56221 agcagattgg attgcttcat ttaatacttc ttctaataag acgatctttc ctttacgagt
    56281 tgataatttt ttaccacctt gcgtgatcaa accaaatgga atatggtgca tgtcgtcaga
    56341 ccagtcaaag cccatttcct tcaagacagc tttcaactgt ttaaaatgat agctttgttc
    56401 attccctact acatatagag attgtttgaa gtcgtaagta cgtttacggt acaatgcagc
    56461 agctaagtca cgtgtaatgt atagtgtcgc accgtctgac ttcttaatca acgctggatt
    56521 caggtcataa gcagataggt caacgatctc tgcaccttta tcctcgttca gcaaatgttt
    56581 ttcttctaaa agtttgacga tttcatccat cttgtcattg tagaaagctt caccgttcaa
    56641 cgaatcgaaa cgtacttcca gcagatcata gattttattg aattctttca tcgattcatc
    56701 acggaaccat tgccataatt gaatagcctc tttatcgcct tcttccagac gtttgaacca
    56761 agcacgagct tcttcattta attctggttc tgtttcagct acttcatgga attggacgta
    56821 taaacgaagc aattcattga ttggttctgc tttaacagct tcttctgtac cccatttttt
    56881 gtaagcgacg atcagttttc caaactgtgt tccccagtca cctaaatggt tgatgcggat
    56941 tggctgataa ccgatttttt ccataatgaa accgatcgaa ttaccgataa ctgtcgaacg
    57001 caaatgtccc attgagattg gtttggcaat attaggagaa gacatgtcga ttggtactgt
    57061 tccttgattc ccgatgttgc tatccccata atgttctttt tctttcacta ctgtttgcaa
    57121 aacttttttg ctgataagtt ctttattcat gaaaaagttc aagtaaggtc cgacaacttc
    57181 gattttttca aagttggcag aatcgatttt ttctgctaaa tctgcagcga tttgctgtgg
    57241 cgcttttcgg taaacttttg ctaatgaaaa ggctggaaat gcaacatctc cgtgttcagc
    57301 tgattttgga ttttctagta attgctcgac ttgttccagt gttaaatcat ctttgacagc
    57361 gtcatagaca gcttttgcga caagatcttt attattcatc tttattcctc ctaaagtgtt
    57421 cccttgattg ttaaacaaaa aaaatctcta gcgacggcat acttagtatg ccatcactag
    57481 agacgagatt tcccgcggta ccactccaat tgtcctaaaa aaggaccagc tccatctgat
    57541 atcggtagac gaccgtctgt ttaaaacaga attctccaag tgcgcttcgt tgtatcttct
    57601 tcattcggct tccaccactt ccgaattcgc tagccaagaa tgatacaagt actctcttgt
    57661 tcaacaaatc ttagtcttat taaactttct tgaattatat cagaaaaaaa aacgaaaggc
    57721 tagtcgtttc ataaaaaaac aatccagatg gcctaaagga gaagaaatac cacctggata
    57781 gctataaatc atttcgtaaa tacgaaagac ttaacaaatt aatcagctac gataatcgtt
    57841 ccttcttcag aagctaaaag attctcgata ttttctaaag aagtgatgat tgccttagcg
    57901 tttggttttg cttcaacaaa tgcaatagct gcttctactt tcggaagcat gcttcctgga
    57961 gcgaattgct tttcatcaat gtattgtttc atttctgaaa cagtaacagt ttctaatttc
    58021 ttttgatctg gtttttggta attgacatac acattgtcta ctcctgtcaa tacgatcagc
    58081 aaatccgcat cgatgatttc ggctaatttt tctgaagcaa aatctttatc gattacggct
    58141 tctcgtcctt ctaatccagt agctgtttct acaacaggaa tcccaccgcc accaacagag
    58201 actgtgataa ctccttgatc gaccagcgtt tcgatgacac gtgcttcttt aatcgagatg
    58261 ggtttagggg aagcgactac ttttctccat ccacgtccag catcttcttt gaatgtcaca
    58321 gtggagtcag cattcatttg ttctttggct tcttcttccg tgtagaatgg accgactggt
    58381 ttacttggat ttttgaatga aggatcattt tcatccacaa taacttgagt gactaaagaa
    58441 accacatctt tatcgatccc tttttccttc agtacttcgc ccatggcgtt ttgtaaccag
    58501 taaccgatag atccttctgt cattgcaaca catgtatcta aaggcattgc cggtgttttc
    58561 tcagaatcag cagcttgctg ctgaatcaat aggttaccga cttgcggacc atttccgtgg
    58621 gagatgatca attcatctcc ttgttcgata aatttcacta aatactttgc tgtttccatt
    58681 aacgcttctt gttgggcttt tgcacttgca tccgtagaca agatggcatt gccccctaaa
    58741 gcgacaacta cttttcgttt ggccatttca ttcgtccttt cttcagttct accgaatttt
    58801 ctagataaca aaacgagcca gcgttttgtg attttccctc aatgctgact cgttttttcg
    58861 tgagatgaat gtggttatgc ttaaacgcga gggataaaca agttacctaa tgttgctgcc
    58921 atgatcgctt tgattgagtg catacgattt tctgcttggt caaattgacg agcatatttg
    58981 ctgcggaaga cttcatctgt tacttccatt tcagtgatgc caaagcgttc tttcatttgt
    59041 tcaccgtaaa cagtgtttgt atcatggaaa gctggcaagc agtgcaagaa gatcaaacga
    59101 tctgtgttgt gtgttttttc taccatttcc atattgattt ggtaaggttt caacaatttg
    59161 atacgttctt cgaatttatc ttcttcaccc attgataccc atacatcaga ataaaggacg
    59221 tctgctccgt ctacaccttt atcaacatcg tcggtaatca tcaattgtgc accggatttt
    59281 tcagcaaagc cttctgccat tttgacgatt tcttcttcag gttgtaattc ttttggtgca
    59341 acgatacgca tattcgctcc taaaattgca cctgtgacta ataaagagtt agccatattg
    59401 tttcgaccat ctccgcagta agcaacagtg ataccttcta ctgttccaaa gttttcttgg
    59461 atagttaaaa agtcagcgat catttgtgtt ggatgccatt catcagtcaa gccattccaa
    59521 actggaacac cagagaattc tgctagttcc tctaccattt tttgactgaa tccacggaat
    59581 tcgattccgt caaacatacg tcctagtact ttagctgtat cttctgtgga ttctttttta
    59641 cctaattgga tatcatttgc acctagatat tcaggatgtg cacctagatc gatcgctgca
    59701 gtagtaaatg cagaacgagt acgtgtagat gttttttcaa ataaaagcgc aatatttttt
    59761 ccttctagat agtgatgtgg gataccacgt tttttcaagt ctttcaagtg ttctgaaaaa
    59821 tcgatcaaat attgtaattc ttcttttgta aagtcttttt ctgctaataa gcttcttcct
    59881 tggaatactg attctttcat attaaacatt ctcctttaga ttgtttttat ttaagattaa
    59941 agaggaaatc ccgacggcag ctgacagtaa gactgccgtc aggaaacaaa ttacttcaag
    60001 tcttcacgga caagtggttg gctcatgcag cgtggaccac cacgacctcg tgacaattca
    60061 cttgaattga tttctaacac tttgatgcca tagctacgaa gcaattcgtt cgatacataa
    60121 tttcggttat aagtgactac aacacctgga gcgattgcca atgtgtttga tccatcattc
    60181 cattgttctc gaggtgcaac gatctcatct ccattaccag ttgggatcag tacaagatca
    60241 tctaatccaa gagcagcttt catcgtttcg tgtaagttat ctgaatgagt aatcttgata
    60301 tcatcaccat ctggttcgat tgtaaagaca tccatcttac cgtctttact ttgaattgct
    60361 ggatggatag tgaatttatc gtgatctacc attgtaaata cggtatccaa atgcatcatt
    60421 gcacggttgt tcggaatttt gattgccaac actttttcaa atcctgaatt ttttgcgaat
    60481 aggtggcgtg ctaatttttc taaagctttc gcattagttc gttgagaaat cccaacagct
    60541 actactttat cgcttaagat caattcgtct ccgccttcga tatgatctgg attttcacga
    60601 tccaaccata cttcgattcc tttatttgca aatcttggat gatgtttcaa aatatattct
    60661 gtaaacatcg attcacgacg acgtgcttca aaagtcatct tattgactgt catcccattt
    60721 cccattgatg cggaagggtc gcgtgtaaag tacaagtttg gcattgggtc catgtaaaat
    60781 ggatagtcat cgtctgctga cagatcatat agactgctag aacgtacttc gatatctttt
    60841 gtacgaaccc cagccatgat tttatctacc atttcttgcg tttccattga tagaaggaac
    60901 tcatgaagac cctctcttac agcattcgat gcaatatgag attcatccaa cattttattc
    60961 aagaattgtt ctttgacatt gcctgcgtca atcgcttctg ccgctaattt ttccaagtaa
    61021 agagtctcga cgccttcatt ttgcaatgtc ttcgcaaagt tgtcatgttc ttcttgagca
    61081 atcggaagat atggaatatc atcgaacaac agacgatcca taatatctgg tgtcaaattt
    61141 tccacttctt gtccaggccg tttcagtaaa actgtcttta atttccctat ttcagagaaa
    61201 acgtgaatag gtttatccat gttgtgttgc ctccttcttt ttgattacat gtataggata
    61261 tcctcctttt gtaatcactt tcataatttt gtctcattca aaatgagaca ttcctcacat
    61321 taatattcga taattaaata attaaacgtt tttctatttt taagcgtaat ttattcattt
    61381 tttattctgt atacactttc aaaaaaatat ttattcattg aaaaaatttt tttgaataaa
    61441 ttaaaa
//
LOCUS       DAIGSZ010000007        59971 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.007, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000007 DAIGSZ010000000
VERSION     DAIGSZ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59971
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.007"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..1050
                     /locus_tag="NOB31_000460"
     CDS             <1..1050
                     /locus_tag="NOB31_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HCI0972702.1"
                     /translation="FLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMT
                     TGAVVSGAFLGNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILG
                     HNSHSADLASINEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALV
                     LSFIHEKSLTVGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGG
                     LLIKYLIVDTIVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSF
                     DDVGLSKTYLTRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVF
                     TILGGFLLNRRRVKN"
     gene            complement(1331..2350)
                     /locus_tag="NOB31_000461"
     CDS             complement(1331..2350)
                     /locus_tag="NOB31_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0972703.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(2372..3379)
                     /locus_tag="NOB31_000462"
     CDS             complement(2372..3379)
                     /locus_tag="NOB31_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI0972704.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(3372..4037)
                     /gene="pgmB"
                     /locus_tag="NOB31_000463"
     CDS             complement(3372..4037)
                     /gene="pgmB"
                     /locus_tag="NOB31_000463"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCI0972705.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(4030..6324)
                     /locus_tag="NOB31_000464"
     CDS             complement(4030..6324)
                     /locus_tag="NOB31_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCI0972706.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            6584..8749
                     /locus_tag="NOB31_000465"
     CDS             6584..8749
                     /locus_tag="NOB31_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0972707.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            9053..9886
                     /locus_tag="NOB31_000466"
     CDS             9053..9886
                     /locus_tag="NOB31_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCI0972708.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(9988..11688)
                     /locus_tag="NOB31_000467"
     CDS             complement(9988..11688)
                     /locus_tag="NOB31_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972709.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            12195..13355
                     /locus_tag="NOB31_000468"
     CDS             12195..13355
                     /locus_tag="NOB31_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0972710.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            13371..13814
                     /locus_tag="NOB31_000469"
     CDS             13371..13814
                     /locus_tag="NOB31_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0972711.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(14297..14827)
                     /locus_tag="NOB31_000470"
     CDS             complement(14297..14827)
                     /locus_tag="NOB31_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HCI0972712.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            14932..15483
                     /locus_tag="NOB31_000471"
     CDS             14932..15483
                     /locus_tag="NOB31_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0972713.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(15636..16109)
                     /locus_tag="NOB31_000472"
     CDS             complement(15636..16109)
                     /locus_tag="NOB31_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0972714.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            16247..17719
                     /locus_tag="NOB31_000473"
     CDS             16247..17719
                     /locus_tag="NOB31_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI0972715.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            17716..18426
                     /locus_tag="NOB31_000474"
     CDS             17716..18426
                     /locus_tag="NOB31_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HCI0972716.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            18778..19062
                     /locus_tag="NOB31_000475"
     CDS             18778..19062
                     /locus_tag="NOB31_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HCI0972717.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(19379..19762)
                     /locus_tag="NOB31_000476"
     CDS             complement(19379..19762)
                     /locus_tag="NOB31_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HCI0972718.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(19764..20348)
                     /locus_tag="NOB31_000477"
     CDS             complement(19764..20348)
                     /locus_tag="NOB31_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HCI0972719.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(20395..21870)
                     /locus_tag="NOB31_000478"
     CDS             complement(20395..21870)
                     /locus_tag="NOB31_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HCI0972720.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            22051..22362
                     /locus_tag="NOB31_000479"
     CDS             22051..22362
                     /locus_tag="NOB31_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972721.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(22477..24813)
                     /locus_tag="NOB31_000480"
     CDS             complement(22477..24813)
                     /locus_tag="NOB31_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0972722.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            24955..25623
                     /locus_tag="NOB31_000481"
     CDS             24955..25623
                     /locus_tag="NOB31_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0972723.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            25626..26669
                     /locus_tag="NOB31_000482"
     CDS             25626..26669
                     /locus_tag="NOB31_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0972724.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(26906..27787)
                     /locus_tag="NOB31_000483"
     CDS             complement(26906..27787)
                     /locus_tag="NOB31_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0972725.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            27946..28674
                     /locus_tag="NOB31_000484"
     CDS             27946..28674
                     /locus_tag="NOB31_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HCI0972726.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            28830..29147
                     /locus_tag="NOB31_000485"
     CDS             28830..29147
                     /locus_tag="NOB31_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0972727.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            29140..29748
                     /locus_tag="NOB31_000486"
     CDS             29140..29748
                     /locus_tag="NOB31_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HCI0972728.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            29803..30594
                     /locus_tag="NOB31_000487"
     CDS             29803..30594
                     /locus_tag="NOB31_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HCI0972729.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            30732..31220
                     /locus_tag="NOB31_000488"
     CDS             30732..31220
                     /locus_tag="NOB31_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HCI0972730.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            31271..32143
                     /locus_tag="NOB31_000489"
     CDS             31271..32143
                     /locus_tag="NOB31_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCI0972731.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            32319..32681
                     /locus_tag="NOB31_000490"
     CDS             32319..32681
                     /locus_tag="NOB31_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI0972732.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            32690..33442
                     /locus_tag="NOB31_000491"
     CDS             32690..33442
                     /locus_tag="NOB31_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0972733.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            33456..35258
                     /locus_tag="NOB31_000492"
     CDS             33456..35258
                     /locus_tag="NOB31_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0972734.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            35535..36575
                     /locus_tag="NOB31_000493"
     CDS             35535..36575
                     /locus_tag="NOB31_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI0972735.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(36627..38771)
                     /locus_tag="NOB31_000494"
     CDS             complement(36627..38771)
                     /locus_tag="NOB31_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI0972736.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIHAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(39128..40501)
                     /locus_tag="NOB31_000495"
     CDS             complement(39128..40501)
                     /locus_tag="NOB31_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0972737.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(40501..40896)
                     /gene="rbsD"
                     /locus_tag="NOB31_000496"
     CDS             complement(40501..40896)
                     /gene="rbsD"
                     /locus_tag="NOB31_000496"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HCI0972738.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(40924..41841)
                     /gene="rbsK"
                     /locus_tag="NOB31_000497"
     CDS             complement(40924..41841)
                     /gene="rbsK"
                     /locus_tag="NOB31_000497"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HCI0972739.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(41949..42962)
                     /locus_tag="NOB31_000498"
     CDS             complement(41949..42962)
                     /locus_tag="NOB31_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCI0972740.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(43043..43642)
                     /locus_tag="NOB31_000499"
     CDS             complement(43043..43642)
                     /locus_tag="NOB31_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0972741.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            43828..44529
                     /locus_tag="NOB31_000500"
     CDS             43828..44529
                     /locus_tag="NOB31_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0972742.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            44539..47250
                     /locus_tag="NOB31_000501"
     CDS             44539..47250
                     /locus_tag="NOB31_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0972743.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            47701..49329
                     /gene="treC"
                     /locus_tag="NOB31_000502"
     CDS             47701..49329
                     /gene="treC"
                     /locus_tag="NOB31_000502"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HCI0972744.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(49389..50570)
                     /locus_tag="NOB31_000503"
     CDS             complement(49389..50570)
                     /locus_tag="NOB31_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0972745.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            50822..52345
                     /locus_tag="NOB31_000504"
     CDS             50822..52345
                     /locus_tag="NOB31_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HCI0972746.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(52414..53142)
                     /locus_tag="NOB31_000505"
     CDS             complement(52414..53142)
                     /locus_tag="NOB31_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0972747.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(53155..54435)
                     /locus_tag="NOB31_000506"
     CDS             complement(53155..54435)
                     /locus_tag="NOB31_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI0972748.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(54576..55178)
                     /locus_tag="NOB31_000507"
     CDS             complement(54576..55178)
                     /locus_tag="NOB31_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCI0972749.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            55423..55629
                     /locus_tag="NOB31_000508"
     CDS             55423..55629
                     /locus_tag="NOB31_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972750.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            55941..56660
                     /locus_tag="NOB31_000509"
     CDS             55941..56660
                     /locus_tag="NOB31_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI0972751.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(56741..57424)
                     /locus_tag="NOB31_000510"
     CDS             complement(56741..57424)
                     /locus_tag="NOB31_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HCI0972752.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            57643..59829
                     /locus_tag="NOB31_000511"
     CDS             57643..59829
                     /locus_tag="NOB31_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCI0972753.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        19145 a        10692 c        12146 g        17988 t
ORIGIN      
        1 tttttaccga cagcatttct tgtttgtgca attgtcggag tgactgtcgg cagttcattt
       61 acaacgattt cgacgattgg aattgctttt ttggggatcg gtcatttact tggattcaat
      121 gatgcaatga ctacaggcgc agtcgtttcc ggtgcctttt tagggaataa ctgctcgcct
      181 ttatcagata cgaccaactt ggcagcgggt attggaggag ttaatctatt cgaacatatc
      241 gctggtatgc gttatacgga tttcccagca ttcgtccttt cgttgatttt ttatacgata
      301 ttaggacata acagtcattc agccgatcta gctagtatca atgaaatgat ccaaaacatg
      361 aaagcgagct tttggatctc tccttggaca ttgattccac tagttatttt atttgggggg
      421 gcaatcaaaa aaattccggc tatccctaca ttactagcgg gatcgacagc tgctctcgtt
      481 ctttctttta tccatgagaa aagtttgacg gtcggaaaag cagcagacat cttgatgaat
      541 ggttatgtcg caaatacacc tgatccaaag ctagatgaac tgctttctcg aggcgggatc
      601 atgagtatgt taggttctgc tagtttgatt ttacttgcat tggcattagg tgggttactg
      661 atcaaatatc tgatcgttga taccatcgtt caagaattaa aagaaaagat ggaccgacct
      721 tctcgtttag tcgggtttac tgccttgagc tgtatcggaa tcaatctgat cgttggagaa
      781 cagtatctgt ccatcattct tccaggagaa acattcaagc gttcttttga tgacgttggc
      841 ttatcaaaaa cctatttgac acgaacacta gcggattcag gtgcgaccgt caattctctc
      901 gtaccgtggg gagtcagcgg cacattcatt atgggaacga tgaaagttag cgcgttgcat
      961 tacttgccat tcgccttttt ctcgattctt gcacctgtct ttacaatatt aggcggtttt
     1021 ttattgaatc gtcgacgtgt aaaaaattga aggaaggaaa aaagaggctg ggacagaagc
     1081 gtttaactcc aagaaataag aagaaactca agaaaattgc tttttaaatt tttgtgaatt
     1141 tcagcttatt tccgaaggag ttgcttctgc ttccgccgtt tatacgtgtt tagagcgtga
     1201 gacaaaagtg ttctttactt ttgtcccacg ctctttttta cagataaaca atgtgttaga
     1261 agtagtatct tcttttacat aaaaagctga ccataggata aatggtcagc gtatttagtg
     1321 agtcagctat ttagtatggg ttttctaaag gaacgactgt ctctcttttg atcaagcgat
     1381 gagggatgac caaacgtacg ccactgctca attcttcatg gatcaattcg cgcagctttt
     1441 gcatagcgac acgtcctaat tcggagatat cgatatcgat acttgtaagg taagggtgtg
     1501 ttaatgttga gaagatcgag ttgttgaagc taatgacgga gagtgtctct ggaatgacat
     1561 agccatacat ttgcgccaac tgcatcgtgc gaagggcgaa gatatcgtca atgaccacca
     1621 atgctgtggc ttcgttttct ttcaacgttt tctcaaagga cagataatcc tccggatgct
     1681 ctagtactac actggataac gcaggaagac cagccatcat cattgctttt tgataaccga
     1741 aatatcgttc gaaatacaaa ctttcatgag tcgtgtttgt cacaaacagg atattcttat
     1801 gtccattctg gatcaaaaat tctgttgctt gtttacctag aagctggtta tcattatcta
     1861 cataaacgat ttcgttctca tgatgataag gctgtccgat caaagtgaaa gggatgtggt
     1921 tttggtataa ataatcaatg acagtatctt gactatctga atacactaga ataaaaccat
     1981 ctacttgttt ttgtaaatgc atacgctgga cgttctctaa cagcaattca aaatttttag
     2041 cagtagcgat tgctgtagtc atatcataat tccgcgcttc ttcgttgatt gcttccatga
     2101 tctcaagata aaatgggtta ccgatccgct cttttgaatc aagagggggt aagattacgc
     2161 cgatggcact ggaaatgcgt tttcctagat tgcgggcagt catgttagga acataaccta
     2221 gttcatccat aatttttcgg actttcttct ttgttgtctc ggaaatacta ggatgatcgt
     2281 tgatgacacg agagacggtc gaggtggcaa caccggcttt tttcgccaca tcttttacgg
     2341 taatagccat gataaaaaca cctttctctt gttattgtgc agagaaccga taaatcgtct
     2401 gactgatccg ttcttgacca ggatggaggt tgatcgatcc aaatttgggg aaatgaacga
     2461 tatcagggat ttcttgcggt tcgattgcta atccgtagtt tgaatgcatc tgttttccat
     2521 tgacagagaa atcagcttcg aatccagtcg tagaaaataa taccatactt ttattagaag
     2581 ttgctatagt catttggcga ccagaatgct tctcgaataa ttgtaaggaa gttttggaaa
     2641 gcctaggatg atgcaaaaga aatacatcat ctagtccatc tggataacat gcaaggatct
     2701 cttgcagtgt tggggatttt ctaaagtcga ttggcagttt ttcttttttt gtccaatttc
     2761 cagtaggcag tttttcttga tctaattcaa gcacaccatc taaaaagacc gttaactgat
     2821 gttcatagat gtctcttgtt ccatttcctg aaaggttgaa gtaggcatgg ttggtcggat
     2881 tgcagatggt ttcaacaagg ctactagcag aggttgtcat ctctaattcg ttttttgtta
     2941 aacggtaagt gatcgtagca gtgattggtc ctggataggt agaaaattca tcttttaagt
     3001 aaaagaccac acctattgat gatggagttt tgaaaacttc tacttcccaa aattggaaag
     3061 accagccttt cgtgccaccg tggatatggt gtgatccgca gtttttctcc aatctatgct
     3121 caccccaaga agcatcccgg atccttccgg ctacaggtcc gacagttgct ccaaaaaagc
     3181 ttttgtctgt tagaacatct tcgaaacgat cgtaagacaa taaaacattt tctgattttc
     3241 cttctttgtc tggtgcgaag atttggtgca ggcgggcacc gtaattgaga agaacgactt
     3301 ctaagtagtc gttcttcaat gtgattttct ttatttcagt ctctggaact ggtacgacgg
     3361 agatctctgg attatccatg gtcatgccac ttttctttca agtaatcgat cgtaagaaaa
     3421 gtcgtatcag ggacaagcgg gatctcctct ccaaggtctt cagcacgtcc cacgccaatt
     3481 ggttgagcgc cacttgagag gatggcttgg ataccggctt gcgcgtcttc gatcccgata
     3541 cattcttctg cttttagtcc gacagctttt gctgcaagga ggaagatatc tggcgcaggt
     3601 tttccgtttg ttgcttctgc cgggtcggca atagcatcaa agtaaggtgt aagacccatt
     3661 ttttcaagta ggaatggccc gtttttactt gcagaagcaa gagcaatctt gattttttct
     3721 tcttttaaag aatccagtaa aggcacgacc ccggggaaga catcttttgg ttcgatcgtc
     3781 tggatcatct ctaaataata atcgtttttt cttttcgcta attctgcaaa ttcttccttt
     3841 gaaaaagagt gttcttttcc gccataagct aaaagcaaag agagtgagtc ttctcggctg
     3901 acgcctttta gctgttcgtt gaatgtgtgg tcgatcgtaa tgccgatttc ctgaccaagc
     3961 tttcgccaag cacgataatg gaattcagca gtatcggtaa tgacaccgtc taaatcaaac
     4021 aatacccctt taaacatttg cttcctcctt tcttagcgtt atttctagac gatccgctaa
     4081 agaataagac tgttcataga cgtaaatttc tagaggagaa ccttctaata actcgaaagt
     4141 aacttgttca tctgtgactg agatgaacaa taaacgtccg cgataattga tatggaaaga
     4201 ataagctttc caagtttttg gcagaaatgg tgcgaatctc aactgatcat gggcagtttt
     4261 catttgagca aatccttgga caatcgacaa ccagctacca gtcatggaag tgatgtgcaa
     4321 gccgtcttct gtgtcgttat tgtaattatc caaatccaag cgagctgttc gctggtacat
     4381 ttctacagct ttgctttcca ttcctaattc tgctgctaaa atcgaatgga tacttggcga
     4441 aagggaagac tcatggacag tcattggttc atagaaatca aagttttttt gcttttcttc
     4501 ttttgtaaaa gtatcattga agaaataaat cccctgtagt acatctgcct gcttgatgaa
     4561 gcaagatcta aggattttgt cccaagacca atgctgattc agaggaagat cgcttgtggg
     4621 aatatcggat acaggcatga gatctttatc taagaatgtg tcatgctgga caaagattcc
     4681 taattcttcg tcaactggga agtacatgtt ctctgcgata tctttccatt tggctagttc
     4741 ttcttcgctg atagtgatag cagcttcttt ttgataagtt aaataatttt ctcgcgtgta
     4801 acgcaagacc caagctgcga tcgtatttgt ataccaattg ttattgatat tgttctcata
     4861 ttcgtttggg ccggtcacac cgtggatcat gtatttattt gctcgttttg aaaaatggac
     4921 acggtctgcc cagaagcgtg cgatttctgc taaaacttcc agtccttcat ttttcaaata
     4981 ttccgtatcg ccggtgtaat tcgtataatt gtagattgca taggcaatcg cgccatttcg
     5041 gtgaatctcc tcgaatgtga tttcccactc gttatggcat tcgacaccag tgaaggtgac
     5101 cataggataa agcgcgcctt ttaatccttg ttgctgagcg ttgtggattg cttgcggcag
     5161 ttgattatgc cgatatttca gcagattctt agttacttca ggtttggcta aagcaagata
     5221 aagagggaca gcatacgctt ctgtatccca gtaagtggct ccgccgtatt tttctcctgt
     5281 gaatcctttg gggccgatat tcaatcgttc atcttcgccg tagtaagtag agaatagttg
     5341 gaacaaattg aatcgaatac cttgttgtgc ttcttcgtct ccttcgatga ccacatcggc
     5401 aagcttccat cgttctgccc aagccgctgt ttgctcttct tttgcttgga tataattgtt
     5461 tgtctggttc gttaattctg agacagcttt ttctgcttgc tgcgcttctg gaatatctct
     5521 actagtaaga acgataattt ctttttccac tgaccatgtc tcaccttgag ataattctgc
     5581 agacaagcaa ccatgtaatg ctaaagtatc ttcgtgatag tcagggatga ctgattttcc
     5641 attaacgaaa tggcgcattg ctgcagtaac agtaaattgt tcaatcccaa agttgtttgg
     5701 aatagtttta gtcgtcaaat agccgatttc ttctatagtt ccacgatcaa tctcattcca
     5761 aaaatgttca tcatagttgc tgtcttcgtt ttgaacattt ccatccaatt ttgatacgag
     5821 tttgactgtt ccgctacctt caagcatttc tatagttaaa tagatataag ctgattcttt
     5881 tttgacaatg ctcagaaaac gttcgaagga aatgcgtact ttattagtag aagtagtgat
     5941 tgtgaatgta cgagataata caccattttt catatctaat tcccagtaaa agtcttctgg
     6001 ttccaaagaa gccaagtcga tcagctgatc gttgatcgaa atatctatcg cgataaagtt
     6061 caaggcgttg atcacttttc caaagtattc tggataacca tttttccacc agccgacacg
     6121 tgtcttatcg ggataccaga cacccgccaa ataagtacct tgatggtggt cccctgagta
     6181 agtttcttca aagttcccgc gcatccccat ataaccgttt ccaatacttg ttaaagattc
     6241 ttgcagtcga agattttttt tatctaattg tgtcgtgctg attttccatg gatcaatagc
     6301 aaatagtcgt ttgatctgtt tcatttttct cctcctaatg agctgtttta tacgttcata
     6361 ataaacgcaa ccgattgcac aagtcaatag acaaaagaaa atatttcata gaaaaaagct
     6421 taaaaaaata aatttttagg agaaaattat agaagggaac acacgtatta taggttttat
     6481 agaatggtat agacagaaaa ataaaaaata aagcatttac aaaaaagaaa acgcacgcta
     6541 taatacgttt aacgaaaccg attgcgtaaa ggagctaaac ggaatgaaaa agatatttag
     6601 ttttgagttt tggcaaaaat ttggaaaggc tttaatggtt gtggtagcag ttatgccggc
     6661 agctgggttg atgatcagta tagggaaatc aattcccttg atcaatcctg attggacgcc
     6721 gcttgtcaca acgggcggag taattgaaaa tattggttgg gcaattattg gtaatcttca
     6781 tattttattt gctttagcaa taggaggaag ttgggcaaaa gaaagagcag gcggagcatt
     6841 tgcagctggg atctcattta ttttaatcaa tcggatcact ggggctatct ttggtgtcac
     6901 aagtgacatg cttgcgaatg aagatgcatt tacccacact ctgttcggta cgaagatcat
     6961 ggttaaagga ttttttacaa gtgtattgga agcaccagct ttgaatatgg gagtattcgt
     7021 agggatcatc gctggatttg tcggggcaat ggcttataat aagtactata attatagaaa
     7081 attgccggat gctttgtcat ttttcaatgg aaagcgcttt gttccgtttg ttgttatctt
     7141 atggtcaaca atcgtggcat tgattcttgc tgtggtgtgg ccaaacgtac aggctggaat
     7201 caataatttt ggtttatgga ttgcagaatc acaagaaagc gcaccgattc tagcaccgtt
     7261 tttatttgga acattagaac gtttactatt gccatttgga ttgcatcata tgctgacgat
     7321 tcctatcaac tatacacagc ttggcggatc gtatgagatt ttatcaggcg cacaggcggg
     7381 gacacaagta tttgggcaag atccgttatg gttggcttgg gccactgatt tagtgaatct
     7441 taaaggtgca ggggatatgt cgcaatatga gtttgtgttg cataactgga cgccggctcg
     7501 tttcaaagta ggacaaatga ttggttcttc aggtatcttg atgggaatgg cttttgcgat
     7561 gtatcgtaat gtcgatcctg ataagaaagc aagatataaa tcaatgtatt tttcagcagc
     7621 gttggctgtc tttctaacag gtgtaacaga accattggag ttcatgttta tgtttgctgc
     7681 tgtgccatta tatgtcattt attcagtgat ccaaggggct gcatttgcga tggcagatat
     7741 cttgccattg cgggtccatt catttgggaa tatcgaattg ctgactcgga caccgttagc
     7801 tatcaaagcg ggtctaggtg gagatcttat caacttcgtg ttgtgtgtga tcgcttttgg
     7861 tgttgttacg tatttcttag caaatttctt gatcaaaaaa ttcaactttg ctacaccggg
     7921 acgtaacgga aattacgaca atgacagtga agaaaccgtt gtatctaaca gcggaacagg
     7981 aacagcagat cagcaagtgg tccagatcat tcatttgctg ggaggaaaag aaaatatcaa
     8041 agatgtcgat gcttgtatga ctcggttacg cgtaagtgta aatgatcgag aaaaagtagg
     8101 gactgaagaa gcctggaaac gagcaggggc gatgggattg atcgtcaaag acaatggagt
     8161 ccaagcagtt tatggaccaa aagcagatgt cttgaaatca gatatcgaag atctgctgca
     8221 atcaggagca gagattccag agccagaaat ggtttctaca ggaaatggac aagcaggtag
     8281 taagcaatac ttaggtatag aacaagaact agtttccgca gcttctggag aagtgattcc
     8341 tttatctgaa gtaaaagatc cggtattctc acaaaaaatg atgggtgacg gctttgctgt
     8401 tattccaaca tcaagagaag ttgttgcgcc gatcgctgga aaagtgacaa gtattttccc
     8461 tagcaaacat gcaattgggc tggaaacgaa agatggtatc gaagttttga tccatatggg
     8521 aatcgataca gtccaaatga atcagccagc ttttgagatt gctgtcaaag aaggccaaga
     8581 agtaggaaca ggaacgaaat tagctgagat ggatcttgat gtgatccaaa acgaagaaaa
     8641 agatccaacg atcatgatcg tatttacaaa cgataaagta gaagaagtag tgatcaagca
     8701 attaggtaca gtgacagctg gtaaagtgat cggctccatt aaaatgtaag gagaggttgt
     8761 gaaaaagctg tcctgcatca agtcataaga acagccaaac aaaaatagct cctcctattt
     8821 ttcgtttggt tgggcttatt accgagaagc agcagtttga atactgttta gtggagaggt
     8881 cgtgaaaaag ctgccctgca ccaagtgata aaaacagcca aacaaaaaat agctcctggt
     8941 ccattgagct tattactgag gagttagcag gagaacacta tttgctggag aggttgtgac
     9001 aaaaattttg tcacaaccct tttgtttcga aatgaagaca aggagaaaac caatgaaatt
     9061 catgacactc aacacgcata gctggcttga gccagaacca gagaaaaaat tgcaagaatt
     9121 agcagataag atcctgttag aagattatga agtgattgct ttacaagaaa tcaaccaatt
     9181 actggaatct gaagaagtag aacctgcgaa gctaatgaag ttctgtccgg taaagaatca
     9241 agtacctatc cgtaaagata attttgccta ccgtttagtt cagcttttaa aggaacacgg
     9301 aaaagagtat ttttggagtt gggaaatgag ccacatcggt tatgataaat atgaagaagg
     9361 aaatgcactg cttacgaaaa aaacattgga aagtcaggtc cttaccgtct cccaatttca
     9421 aaagaaagaa gattatcaga cacgcaagat cttgattggg aaaacaaaga tagatgatca
     9481 ggacattttt gtctcgagct gccacttttc ttggtggaca gataaaaaaa gtggctttta
     9541 ttttgagtgg aaaaacttgg aaaactactt tttggaaact cgcgtaccac tttttttcct
     9601 aggtgatttc aataatccag tagactctca aggttattat actgtaagag aaagttgcct
     9661 tcttcttcaa gattcgtatg ttgtcgcgaa tgaaaaagga aaagcagcta ctgtggaaaa
     9721 gaaaatagat ggttgggaac aaaatacaga aaaattgcgt atagatttta ttttcgtccc
     9781 tgaaggaatg caggttaaaa aatatcaacg gatttttgat gggatcgata gtccaatcat
     9841 cagtgatcac tacggggtgg aaatcgaatt agatgtgaac gaataaaaaa tataacatat
     9901 aacataaaaa aactgattaa aataaaactc tccaaacgat tataccgttt ggagagtttt
     9961 ttgatcggat gtatttatcc cttttgccta agcacgtaaa agcttgtatc tatgataaat
    10021 aaataaacat agcaaggtaa accagccaat caaagtaaga gaaagaatga aatagaaata
    10081 gattggcgtt tgataatgaa gcgtgagctc gttgattcct ttttgctgct tcacgattgg
    10141 ggtcccgata tctgttactt cataatcagt caatgttttt ccattttgct gtagcacagt
    10201 ccgatcgtag acgataacag ggatatgaac agttttgtcc ccagtgtttt tccacttgat
    10261 tgtcaaaaga ccgcctggat gtgtttttat aaaagttgtt tcgttttcta gtatttcttc
    10321 gttataccgg tcgtatttat tgtcttttgt ctccttatag attggcagat agtcaggtgt
    10381 ggttttttgg aaaacgaaca agctggtaga catatctttg ctgaagaatg ttttccttgc
    10441 ttcttccggc gtatcgaata gataagtatg tcgactgaca aatgtttcat tttcccactt
    10501 ttccagatgc tggtataagt tctggatcgt ctgtgctgaa aaaataagaa tgccaaatat
    10561 acttaaaaga cggaaccact tttgttcaga ccactggttc agtgaaaggg caaggtaaag
    10621 tagaagcaat agcgtaaatg gcacgaaaaa tcgaaatgga aactggatca aactaataaa
    10681 aggcacattt ttttcgatca atgtcgtcca tggaatcaag ctagtagaaa gaaaaaagaa
    10741 aacaagactt gtgtacaaca cgattttttg gaataaggtg ttcttttgtt gaaagaaaat
    10801 aaaaagcaaa aaacctgata atatcaatat aggaaaggcc ttagggtaat ggagccaata
    10861 actgccatcc agatctatcg ccttttgact catttctctg ttaacaaagg gaggaagaat
    10921 cttattccca ctgtaaacaa tagctaatcc tgcccaaata tttgctgtca gaacaaaata
    10981 aagcaagacc gacttaatca gttgaagcag tgcttttcct ttttcagtct ggttaaaaaa
    11041 gtaataaaga taaaaaggga tatacatcaa agctaacatg atcgaagaca gtaaatggat
    11101 ctgtgtcata agtcccactg agacagcgac tttgataaca gggaactttt tatgaaggac
    11161 gaaatcagca atagggatca tacataaagg ataaaaacaa gtcccccagc tagtgaatcc
    11221 ttggttgata gaccagtatt gaatagaata cgtactcatg aataaaacgg ctactggtac
    11281 acttacccaa tttcgaacat tgacatatct cagtaaaatc agcatagaaa atcctgaaat
    11341 aagataaaga atgaaatttg aaagaatctg ataatgaaac cagctacctg caagcaacac
    11401 gatcaatcct tgtaaataag cgaaaaatgg gccgtaaacg gcattcacga tcctgccact
    11461 ttgctggaat ccataaaggg aaggaaaata atggaaatcc ccatatttaa tttgttgcgc
    11521 ggcatcatag aaccgattgt aatggaatgg ggcatcagca cccaaaatta gtttatgtgt
    11581 gaataaatga ggcatgagaa atgccaaagc aatgaaaaaa attgctaaaa atgggccata
    11641 ttttttcaat tgtcgaactc ctttgcaaac tttagataaa ttcatcatat atcctatgcg
    11701 agaggtaggc aagaaattag aaaattcatg aaaatattta tgaattttac aagaaaaaca
    11761 taagtgaaag ttctaaggag agaggatgcg acataagttt tgttgcatct ccttgttttg
    11821 aaacagaatt tttcttaata ctcgaaacaa agtagctttt tcatgacctc tcggtaaacg
    11881 gtgttcaatc agctgcttct cggtaataag ctcactagcc tagaaaatat gagaagctat
    11941 tttctgacta gcgctcttat tactcaaagc ataacgcagt tttcacaacc tcttccttaa
    12001 acggtgttca aaagcttgca tctgcggtaa taagcccaac ccaacaaaaa atatgagtag
    12061 ctattttttt gggctgtact tattacttga tgcaggacag ctttttcaca acctcatcgg
    12121 ctttcatttt ctattttttt cctgaaccca tataataaaa gaaagaacaa aaaaacttgc
    12181 aagggaggac acatgtgaag cagagtaagc aaaaacagtc tcgtcgactt ttgtttcgtt
    12241 tgtttttatt aatatgtatc gtcgtagggt tactgatcgc tttatatcca ttttatgtgg
    12301 attctttaaa tagttttatt gatcaaaaac gtatcgaaca agtacaaaaa cggaccgcag
    12361 ctgaaattga agtgcagcga aagaaaatgg aggagaaaaa ccaacgatta actgaccaag
    12421 gattcaatcc tggtactgat cctttcaatg aaaagaacag aaatgaaagt acaacatcca
    12481 gccaattaga ggaatggctg atcggaagta tcaatatacc taagatccaa ttaaatattt
    12541 cactttatga tcggctcaat ggtaggatcc ttgaaaatgg agcaggcgtc ttgcaaggaa
    12601 cctctttccc gcttggtgga aattcgacgc attcagtgat ctctgctcac agcggtttac
    12661 ctaatcgacg gttatttacc gaattagatc gtttagaaaa cggagacacg tttattttga
    12721 ctgttttggg ggagaaattg gcttatcaag ttaaaaatat acaagtggta ctgccagatg
    12781 acacgtctgt tctaacgatt tcagaaggag aagacttagt taccttgctt acatgtacgc
    12841 cgtatatgat caacacgcat cgtttgctag tgacaggaca tcggattcct tataacgaat
    12901 cggtaaaaaa agaagaagga aaaggaaatc aggaaagaac catgcggcaa tggtttattc
    12961 ttgcaggaac gataatagct gtagtcatac tgttagtgtt tatcggacga ctaatctatc
    13021 agtatagatt aagtaaaaaa gtgcttgatt tttcatttat tattagtgat tcgtcaggga
    13081 aaccggtaaa tggtagttca ttcattttga aacataagaa aaaaacactt actagaaatg
    13141 gtgtgccgtt ttcagtacaa agcgaccatc atgggaaagt caagctggat caattgcctg
    13201 gtggaactta tcgaatcgtt tcagctgatg atcctaaagt tgctgtttct tttggtatta
    13261 gaaaagtaaa acaagagaag atatactttt ttgaggggcg aaaacttgta aaagagcttc
    13321 aaaaaaatgg tttttatttt aaaatcaatg aataagtaag gagagaaaaa atgatccgca
    13381 caacaacaaa attgtctgcc aaagaactgg aatctgttct atcgatttgg ctgcatgcta
    13441 acttggattc tcatgaattc attccatcaa cttattggga gaatcaagta gaatctgtta
    13501 ggaaagcttt accagatgca gtgatttact tagcagaaat agatcaagaa attattggtt
    13561 ttgctggggt gattgatcag tttatcgcag gaatctttgt gaaaagggaa taccggcaac
    13621 aaagaatcgg tacgcaacta atgaaaaaaa taaaagaaac caataaaaca ctgactttga
    13681 cagtctatca aaaaaatcaa tcagctattc atttctatct ttcacaaggt tttacaattc
    13741 aaacacagca aaaagatgaa gcagtaaatg aggaggaact tgtgatgaaa tggaatcaaa
    13801 acgctgattt ttgatgaaca gaataacgaa ataatgctcc cagcctaatt ttttgctggg
    13861 agcattattt cattttgaag tcactaattt aactgtgtga atatgcagtt gttacaatct
    13921 ttgataaacg gtgttcaatc agctgaccct cggtattagc tcaaaaaacg gcaaaatatg
    13981 aggaactatt tttccatttg tttctctaat actcaggtca aaacgctgat ttcacaacct
    14041 cttgataaac ggtgttcaaa cggctgcttc tcggtaataa gcccactagc ctagaaaata
    14101 tgaaaagcta ttttctaact agcgttctta ttactcaaag cataacgctg atttcacaac
    14161 ctcttgataa acggtgttca atcagctgac cctcggtatt agctcaaaaa acggcaaaac
    14221 atgaggaact atttttccgt ttctttctct aatactcagg tcagaacgct gatttcacaa
    14281 cctctctttc acaaccttat tttactcgtt tataattttc atcgaagtat tttccgctac
    14341 ggatatcatc tggcattcca tcgtatggtt cttcgctaat aacatcttca ttgtctatac
    14401 ctgcatcacc catataagtg atcgtagcaa attcaggaac aagtaatttt ggataagttt
    14461 catatttttc acgagctgct tccatttctg cgatatgttc gttttggaaa gtaacagtga
    14521 tttctggatg ttcttcaacc catttaggga aaaagatcat tccgtgaagt ttcttttcat
    14581 ttggcataaa gtccaatgcc acgtctgtcc ctgttggctc tgtccaagtg attttgaata
    14641 cgccgtccgt caatttaacg atatcagctt cttggtcttt tacccaacgg cctttgacca
    14701 ttccgccatg gatacggtaa tcaacagtat ggtcattttt ggcataccat tcatattccc
    14761 aaccattgtc atacgtatag ataaagtgag ttccaataaa atcttccaat tctttaaatt
    14821 ctttcatgtt taagcatctc cttataaatt aaaacatgta ataaactaca tgttttcgat
    14881 tactcattta tgatagaatg gatttaaaga tttgtcaagg agggaaaact gatggcaaga
    14941 aaaaatacac ttcgatatat tttgttaggg ttattaagta agaagaagat gacaggatat
    15001 gaattgaatc aatcgttcaa aaatgaaata ggagaatttt ggcaagcaaa acatagtcag
    15061 atttatcctg aacttgcaaa aatggaagag caaggaatca ttcagcatca agtagagatc
    15121 acaggtgaaa aattggaaaa gaaagtttat gaattaacag aagaagggaa ggaacaattg
    15181 gcagagtgga ttcatacacc caccaatgaa ctaccggtta atcgagacga atttgttctg
    15241 aaattgtatt tcgtcaaaga cgtgaatgat ccggcattag tagaaattat tcagcagcag
    15301 cgtgaccttc atgaagaaaa acgacttcat ctattagagc gaaaaaaaac gatctttcct
    15361 actgaaaaag aaaaacatga aaattacgga cactacctga ttttagcgca tgcgatcaat
    15421 cgggaaacag aatatgcaaa ttggctaaca gatgtattag aagaaagtaa ccgaaaaaaa
    15481 taaaaaaata tccgaacagt gatggagaat tcctttctat atgaaagaaa cgcagatcac
    15541 cgttcggata ttcttatgtt caaacaggcc ttttttcaag tatttatgta gcatctactt
    15601 attaaaaagc ttggtactta ggagattagt ggcgtttaga gttcttttaa caactgttcg
    15661 tagtcagctt tttcatcgac aggaaggagc ttgtaagtta attcgtctgt ctcgttgtca
    15721 tgaatgatgt acatcttagc attctcttct ttgaagttac cgatttgtaa aatcgtatag
    15781 cgttcgtcga tcaattcgat atctttgatt gcttttgaaa aaactttacg gacatggtgc
    15841 attttctttt ggcggatttc tgccttttct gcagcttttg acaaagtaaa tccgtcatct
    15901 aaatattttt tgatcagttc tacttttatg actgtaggta aacgatattt tctaggacaa
    15961 ttcgcatcag cttcgatcga acgaatgaat cccttttgtt cccaatacct taattgacgt
    16021 ggagacacac ctacgatatc acttaattca ctgatgccaa caaccaattg atcattttcc
    16081 aacaaacgtt taagggaagc cccaaccatt tttgtcactc cttttgtcct cttgcttccc
    16141 ttaattatat ccgtattaac ttatgtgtca agtaggttga caaatagcga atttaggact
    16201 aaagtattct agtagtttca gaaaaaattc agaaagaagg agaaatatga gtaacaacca
    16261 acccgtagat atttacggaa aaccatataa tcggacactt ttagttgttg tcttattaat
    16321 tggtacattt tgtaccgttt tgaatcagac cttattgacg acagcttttc ctacattgat
    16381 gaaagctttc gatatttcag cgtctgatgt gcaatggtta acgactggtt tcttgctagt
    16441 caacgggatc atgatcccaa taacagcatg gctgatcaat aaattcagtt caagaaattt
    16501 atatctttct gccatgacga tctttttgat cggaacgatt acttgcttta cagcacctaa
    16561 ttttagtaca ttactaatcg gtcgtttgat ccaagcttgc ggtgtgggag tatcgatgcc
    16621 attattgcaa aatatcatgc tatctatttt cccgccagaa aaaagaggat cagcaatggg
    16681 gatgtcaggg atcgttattg gacttgctcc tgctttaggc cctacattat ctggttatat
    16741 cattgataac taccattggc gtgacttgtt tggtatggta ctgccaatcg ttgttcttgt
    16801 cttggtttta gcattcttcc taatgaaaag tgttattcca ttgtcaaatc ctagcattga
    16861 tattttatcc gctattttat caacgattgg attcggtagt ttactttacg gattttctag
    16921 tgtaggagat gacggctggg gaagcttgaa agtaattggt ttcttagttg ttggtgtgat
    16981 tttcatcgcc ttgttctcat ggcgtcaatt acatttggaa catccattct tggaacttcg
    17041 tgtattcaaa tcatctacat tcacgattgc agctgtttta gctggtgtaa caaatatggc
    17101 gatggtaggg gcagaaatgg tcgtaccatt gtatattcaa aatattcgtg gagaatcagc
    17161 attccattct ggcttgatgt tgttgccggg tgcattgatc atgggggcta tgatgcctgt
    17221 gacgggtgcg attttcgata aatacggcgc gaaacgttta gccatcacag ggatgttcat
    17281 tttgacagcg gcaactgcac catttgcttt cttgacaaaa acgactccag ttttatatat
    17341 cgtgatcctt tatgcgatcc gtatgtttgg gatctccatg gtcatgatgc cggtaacgac
    17401 ttctggtatg aatgcattgc caaataactt gatcagtcat gggacagcgg taaataatac
    17461 attccgtcaa atcgcaagct cgattggtac agctattttg atcagtgtgt tgacgaatgt
    17521 gacaaaagca aatatcccaa gcaaatctgt attggataat acgccattag cttataaaga
    17581 tcaggcaatc aatgccacac tgtcaggtta ccatgccgcg tttatcgtag cgatcatctt
    17641 tgggattctt ggctttatta ttgccttttt attgaagaaa aaagaacctg ttctaatgaa
    17701 agcgggggat aatgcatgat tattggagtt ttgattgtca gcttgcttgc ttttgcttta
    17761 acgaacgtgt tcgctaaaaa aacatggcaa acctttttat ctttgatttt cggactaatc
    17821 ttcgtcgctt cactaagttt gatcgtcgct aatttgtcca atcactttgg aatggaaaaa
    17881 gtaacggaaa caaaaacaga aaaaattgtt tccagtgctg attcccaagg agcagatatg
    17941 cttttgtata aagctttagg gaatggaaaa gaaaaagtgt atctttaccg aacaaatgaa
    18001 aaacaagaaa aaccaaaagc aactggtacg gataacgaaa caaataaagt agaaaagaca
    18061 gacggcgatg ctgaaaaagt gacgaaaact acttattggg aatacaaaaa cgacatgtat
    18121 aaattctggt tcaatattgc tgataacaat cacgaatatg acagccgagt gaatacattc
    18181 aaaatcccag agacatgggt agaattaagt acggaccaag cagccaagtt agctgaatta
    18241 gtgaagaaac agcaaagtac gatggaaagt gaagcaaaag cttatgttca agacggtatg
    18301 gtaaaagcaa tgactgaaaa tccaaaaatg agcaaagcag agcaagaaca acgtacgaaa
    18361 gccttagctg ctgaattcca acaacaagca ttcgcaaaat tagtgaaaga agcaaaaggc
    18421 gaataatatt ttgaacacca tgtaggaggt tgtgaaaaag ctgctctgca tcaagcagta
    18481 agaacaatca gataaaaata gcactccata tttttcatct gattgggctt agtgccgtag
    18541 atgcaagctt ttgaacaccg tttaaggaag aggttgtgag cctgccgttt aactctgagt
    18601 cacaaggagc aatttcaaaa aacagcttct catgtttgtt gactattgtg acttgtgacc
    18661 gaggagttgg caggagaaca ccgtttattc gaaaaaagga actgcgacaa gacttttgtc
    18721 acagttcctt cttttttttg ctatgctata ctagatgtaa aaaataggag aaataaaatg
    18781 agggaaattt attcttttga atcaaaaatc tatgcttccg aagtcggcaa gggcggggca
    18841 tatattattt ttccgtatga tataagaaaa gaattcggtg ctggaagagt taaagtccaa
    18901 gcaacttttg acaatgtgcc gtatgaaggc agtatcgtga atatgggcgt gaaaaatcca
    18961 gatggttcag tctgctacat ccttggacta cgaaaagata ttcgtaaaaa catcggaaaa
    19021 gaaatcggtg atattgtagc agttacagtg aagcaaaaat aaaagaggtt gtgacaaaag
    19081 acgtgtcaca acctcttgat aaacggtgtt caaaagccag tttctcggta gtaagtcaaa
    19141 tttatgcaaa aatgtggaaa cccatgttta caaaattttt cttactactc gaaacgaagc
    19201 ggctttatca caacctcttg ataaacggcg ttcaatcagc tgtccctcgg tattagctca
    19261 aaaacggcaa aatatgagaa gctatttttc catttttttc tctcatactc aggtcataac
    19321 gctgatttca caacctcttc tttcataatg gtttttcacc atctttataa taaactggtt
    19381 atttgatatg gaaatctatt ttttccaacc aatctaaaat cttgtaacct aactcttctg
    19441 acatcggaaa agaggcgttg atttgtgcat tggagatatg gtcaacatgg ataccggaag
    19501 tgatcgtaca acttcccgga acggcagttt tgatgatcac agctattttt tcggctaaga
    19561 catcgtcttt atggaaccga ccatcgtggc tagggaaacg tacagtttgc atctctgtat
    19621 cacgagaaaa tgtagtgact gttccgatat gtggtgtatc tccgcctgtt aaagtgatca
    19681 ataagtcttt accgattact ttaacagcag cttggatcgt gaaacctagt ttggttactt
    19741 caactatcgt ttctttttcc atattaatca ccctgccaac gttttgaatg ctcatttaca
    19801 atttcaaatt gatccaaaag tttcattgta tggtgattaa caagatcttg gatcgtttga
    19861 ggctgattat aaaaagcagg aattggtggt atgatttgca cacctagtcg tgctaattta
    19921 gtcaagtttt ccaagtgaat ggcatttaat ggcgtttcac gaggaacaat gactaacttt
    19981 cgttgctcct tcattgttac atcagcagca cgtgcaatca ggttgtcgcc taaaccaaca
    20041 gagatacctg cgactgtttt catacttgcc ggtacgatga tcattccatc ggtcaaaaat
    20101 gatccgctgg cgacagcagc acctaaatct ttgtttgaat aatggtaatc aaacaggctt
    20161 tcgaattcag ttagtgataa gtcggattcc agctttaagt tctgttttgc ccatggactg
    20221 atgattccgt gtgtttctat catcggatat tcttttagtt tcttcactag gttgatggca
    20281 taaatggtgc ctgaagcgcc acttacacca atcacgattt ttttcttccg ttgtgccaat
    20341 tgttccattt tccgcactcc tttttatgat gtcaaaacag ttgcagatca ttcattattt
    20401 caaatatttt tcccaatctt ctacttcttg gaattttgca cgtacaaaat gttctttcat
    20461 atcgaaagga actgtaccgt caaagatagt ttttgcactt atcccacgga aacgaataga
    20521 gccaggatta tattctggta attctgatgg gtccaatgga tggttcctca ttcctgggat
    20581 cacgatgata tctttatctc cttggaaacg agtgttgaaa gtccaaacta catcgttcat
    20641 gtcgaaaata tcaacatctt catcgactaa aatgactgtc ttcaattctt tgaaggctga
    20701 taaagcaaga atagctgctt gacgctgaat accttcatcc gcttcgtttt ctttacggat
    20761 ttgcatgatg gtcatcaatt taccaccacc tgcaggagga ttgtagacat ttactacttt
    20821 tcctggaata gctttatcga ccaaggcaag aatacttgct tctgtaggaa taccggccat
    20881 agatacgtgt tcttcactgg gaccaatcgt tgtttgcatg attggattgt cttttcggtg
    20941 agtaactgct ttgactttca ctacttgtac agctggatta gcatccccag tatagccagg
    21001 aaattctggc attgcttttc ctgagttcgt gttgatatct tcttgcattg tttcatttgg
    21061 catgatttct gcttcaatga tgaattcagc acgagcaata cccacttcat cgactgctat
    21121 accatcaacg atttgaatag gttcgttacg caaagctcct gcacaccata gttcattgta
    21181 gccaagtgga gtggtaggtg gttcgaaagt cgtgccaatg gcaattgctg gatctaaacc
    21241 aatattgata gtgataggca ttggtttatt caaggcttcg aattgttttt ggaagtgacc
    21301 aatgtggcgt ccgccaggca tgatgtacat accgatcgta tctttatctt ctagaaccat
    21361 acgatggatc gttacatcgc tcattgtttt ttctggatct gatcctaaga ctacacccat
    21421 tgtgatgtat ggaccagcat cttcaggagt atttgtaggt gcaggcaaaa tgttgcgaat
    21481 atcgaagtct gcatcggtag ctagatgaac gacttcttgt gctggagcgt ctgctttgtc
    21541 tactttcaca ggtttgattg gattttctac agcgtctttc aagaaacgac caagtgttcg
    21601 ataatcatgg tgcaaaattt cacctacacg tttacgacta gccattgttc cgatgttcac
    21661 acgtgtgccg gggaaacctt tgatattgtt gaaagtcata gctggtcctt cttgagtcgg
    21721 acgttttact gtaccgccag caccgatata acggtaaaca ccagataatt ctgcttcagg
    21781 atcgatttca atatctgttt cgtgatattg acctggaagt gtttttagtt cttcgatgac
    21841 ttttcttaaa tcatacggtt gatctgtcat gagagattcc tccttagttg tctttaccta
    21901 tctatagtaa aaggtgaaaa agaggaaaac aattcaactt gttcggtaaa gtattctaca
    21961 atggaatgga tgcgtttttt tgataataga ataaactatg atatacttat cactaaaaga
    22021 aagcgcatac ttagtgttgg aggaaggaaa gtgaaaaaaa tggaggagtc atttcctaaa
    22081 gcagtaaaag tggaaaatat agcgaatatt ttgaaagtta catttgaaaa cggagaagta
    22141 aaatacgtga aatctcattg gacagaagag ataaccgatg ccttgcaatt tggaaaaaaa
    22201 ggaagaggaa aaagaaaaaa tcttctcgca ctttctcgta atatgtggat tgggactgaa
    22261 gtaacgattg aagcagatgg aacagtattc ataaatggaa aagacaggta tacgccagaa
    22321 gagttgtggt acaaaggaaa gaaaagtata ccagaattat aaaaaataat taaaaaaaac
    22381 agcgcgaaac aaggaacata ttacttcctc gtttcttgct gttttctact atttcagcgc
    22441 tcttatgact caaatctaaa tgtggttgtc acaaccttat tctgcacgca aagcgatagc
    22501 ggcgtctttt ttcgctgcca ttcgtgcagg aagatgaccg ccaagcatcg tcaatatagt
    22561 agagacgatc actagaataa tcgcatggac aggatttagt tgagcaacat tttttagatc
    22621 cgtcatgttg tataagatgc tattgatagg gaacgtagct agccatgcaa taaacacacc
    22681 taatatccca gaagaaatac ctaaaataca cgtttctgcg tcaaatacgc gagtgatgtc
    22741 ttttttacgt gcacctaaag cttttagtac accgatttct tttgtccgtt caatcacaga
    22801 tgtataagta atgatactga tcatgatcat acttgttact aaagagatcc ctgcaaaagc
    22861 aataaggaca taagtgatag catccatcaa tccgccagtc agttcagtca tcgttccagc
    22921 taaatcagta taaatgattt tatcttcatc tgatttgcct ttattgtaat catctagata
    22981 atccaagatc ttttctttgt cttcaaaatt gttcggataa atcatgatac ttgaaggcaa
    23041 gctgtctcca cctaaataac taagcaatgt ttgtttggca ttttcgtcaa ctttttcagt
    23101 agttaagaca tttacaccac tgtctctttg agctttgacg atttctgatt ctttgttttc
    23161 gttgacgatt tgagtcgtta attgatcgct ataagcgatt cctggagata agagattcat
    23221 tgtagaagaa gatttcacgc gtaggatccc cgagatcttc aattcatcag aagcattctg
    23281 atacatcgca tcataatctg tattagggat aaaattccca gttggaagtt ttgtatagta
    23341 agtattgttg tttactaatt tgaatgttgt accaacgata tcatcaaaat caagtttttc
    23401 gtcttctttc acatcaaatc caagattctt caatgcgttg atattagtat tattattgcc
    23461 gtctacgatc agcacgacat ctgttgctga ggctggataa cttccggcaa gtaaagaata
    23521 attgtctttt aaaaagtttt ctttgctagt gtcaagctgt gtagggaaac ttgacactcc
    23581 cacacctgtc attgctgaca tcgtactaga taaagaaaga gattccgtat caggattttg
    23641 attcgagaag ctgacaggct gtactttgcc atttacatca cgtaaaagat tgattcctgt
    23701 agtacgggta aatccgatat tattacttaa gttaggatcg atgtctgtta cgtaatcgac
    23761 gtatgtttga tcaatcttat tcgtgtgctg tgctttatct tcttcgctga cttttgcagt
    23821 aatcgttttg ctgtctggat aatccgcttt gcttgcaccc aatccggcat cgtcacgagt
    23881 ctggttagtc gttaccttag aaatagtaat cggaaatttc gccatcgttt cagcttgcgt
    23941 gttatcgatt tgtttttgga atccagaaga aagggacaga acgatcgcga ttccgatgat
    24001 cccaatactg gaagcaaagg aggtcaagaa agtacgtcct ttttttgttc ggatattgtt
    24061 gaaggaaagc tttaacgctg tccaaaaact catctttgtt ctgcgtaagt taaattgatc
    24121 atcttttggt cgttcgatgt gaggatggga atctgttaag atcttaccat cagaaaattc
    24181 aatgattcga tctgcgtatt gatgggccag ttcaggatta tgtgtgacca tgatcactaa
    24241 tttttctttc gataactctt ggatcaattc catgatctgg atacttgttt ctgtatctaa
    24301 cgctccggtt ggttcatcgc acaaaaggat atctgggtca ttggctagtg ctcgagcgat
    24361 ggccactcgc tgcatttgtc caccagataa ctgatttggc tttttatgca tatgatttgt
    24421 caagccgact cggtgcaatg catcttctgc ccgttttcgt ttttcgtctt tagaaacacc
    24481 acttaatgtc atcccaagtt caacgttttc aataatgcct agatgaccaa tcaagttgta
    24541 actttgaaaa atgaaaccga tagagttgtt tcggtaggca tcccagtcac tgtccttaaa
    24601 gtctttagta gactttccgt tgattaccat atcaccggaa tcataattat ctagtccacc
    24661 aatcacattc agcatagtcg ttttaccaga accactagga cctaaaatcg ctacgaattc
    24721 tttttgtctg aaagcgacag acacaccatc caatgctttg gtggtggttt cgccgacttt
    24781 ataatatttt tttatatctt ttaattgaag cataatcacc cttctcccgt attgaaatat
    24841 tcggtatact aataagtata tcagaacaat gatcgtagta tacgaaataa atgttaactg
    24901 aagatgaact acaagaaaaa atctagaaat ttttcaaaaa acagagggag atcaatgaat
    24961 cgtattttag tagtagaaga tgatccgcaa ttacagttgc tttaccgttc tgtgttggaa
    25021 cgagcgggct tttcagtcat caccgcattg aatggagagg atgcgctgaa aaaactagaa
    25081 gcgacacgta tagaattaat cattacagat atcatgatgc cgaaaatgga tggctatgac
    25141 ttgctagact cattacgtag caccagattt gacacacctg ttctaatgat tacggcaaag
    25201 gccgattttg aggataagaa acgcgggttc aaattaggag cagatgatta tatgacaaaa
    25261 cccatcgatg tcaatgagat gatcctacgt gtggaagcat tgcttcgacg ttcaaagatc
    25321 aattacagca gtagcttgat aatcggacaa acaaaattag agctagatgc ttatacagtg
    25381 ttacaagatc agcattcgtt gattctgcct caaaaagaat ttctgcttct gtataaatta
    25441 ctgtcttatc ccaacaagat cttcactcgc caacagttga tggatgatat ttggggatta
    25501 gatacgaata cagaagaacg aacgatcgat gtacatatca aacgtttaag gacccgtttt
    25561 gaaaagacgg aagattttca aatcatcaca gtacggggac taggctataa ggcggttatt
    25621 taaagatgaa aaaaaagcta ttttcacaat tatggatcta ttttgctagt attgtcttca
    25681 tttcgatctt agtgacactg ctgtgttttc tcggttttat tttcttattg tctcgacatt
    25741 ctatctcgcc tgctgaatcg gctggaaaac caacgttata cccgttattc gtctttgcgg
    25801 ggttcagtat ggtcgtgggt acaggaatat cgatttttgt tgggcggcgt atcctgcatc
    25861 caatcagtgc gctagggaca aatatgagtc tggtagcaac gggagatttt tcgattcgaa
    25921 tggatgaaca gcagaaagta gcagaagtac agcaactgta taaagatttc aacgttatgg
    25981 tccaagaact caatagtatc gagacactga ggaatgactt tgtgtccagt gtatcccatg
    26041 aattcaaaac accactagca acaatccaag gatatgttca attgttacaa gccccaaatc
    26101 tctctgacga agaacgccaa atatttttat atcggattat cgaaagtatc acgcagcttt
    26161 cacaattaac agagaacatc ttaaaattga acaaactgga aaaccagcgt atccaactgg
    26221 aaaagaaaga gtatcgatta gatgaacaaa tcagagaagt aatcgttttt tttcagccta
    26281 aatgggagaa agaacagcta gaattggata tcgaacttgc tgcagtaaat tacacaggca
    26341 atgaagagtt tttgtaccaa gtgtggctga atatcatgga taacgccata aagtacaatc
    26401 aaatcaatgg acagattcat atcaaactat ttgagacagc cacagagatt gtactggaag
    26461 tgaccgattc aggtgtagga atgaatgaag agaccagaga tcgaatgttt gaaaaatttt
    26521 atcaaggaga tacaagtcgt caaatttctg ggaatgggct aggactttca ctggttaaaa
    26581 aaattctaga actgcatgat ggacgtattg attatagcag tatcgaagga gtaggaacga
    26641 cagcaatgat acggttaagt aaacaatagg aaaaagaata aaacccctaa aaattctatt
    26701 gaaggttttt aggggttttt agtcgttttt ttgtgattag ggaaatgttc ttacggttct
    26761 tttggcataa aaatcgctgc tttcttattg aactacgaga aatgttagag gtgtcattga
    26821 aacaaggaca tgatgcaaga aagagagcga aagtcatgcg tcgctctctt tttttgggtg
    26881 gatagatgga cagaaaatgt agggcttagt tttcttcttg atttaaatac tcccaaaatg
    26941 tatctgaagc caaagaatgc tcaccgactt tacgagtaaa tgcaagataa ctctctgttg
    27001 ttggagaaat agggagaatc acagtatttt cttttaatag attcttgact gttttttcca
    27061 taacaatagc aatccccatg tcatttgcaa tcatattgat gatcaagtcg attcttgctc
    27121 ctttataaga gatttttggt tcaaatccag cttcgcgaca cagatctagt acaggttgat
    27181 acaagttcgt agtggggcca aggagcaaaa agttctcctt tttcagttcg cttagatcca
    27241 atttcttttt actagctaaa ggatgatttt taggtagaac tgctacaaaa tcgtctgttt
    27301 cagtaggcaa ccactcaatc gaacttggtg gggcctggaa acttctagca aagtggatcg
    27361 tgtcactatg ttcattggcg tcattgtaag ttaattcgac actttccact tctttcaact
    27421 ggactgtaaa ttcaggatgg cgtttcaaaa actcggtgat tttggaaaaa cctttataat
    27481 tgatcattgt cggtatcgtt aagatattta atgaaagatt gttgtctttc gtataggttt
    27541 caagcacttc ttgcatagca tggtattgtt ctacgacatt ttttacatat gggagcaata
    27601 agcttccagc ttcggtcaat tcgatttttc tatgggcgcg ttcgaataat ttgacgtcta
    27661 attctgtttc taacgaaaga atctgtttag aaatatttcc ttgggtggtg aattgtcgat
    27721 cagcagtttt ggtgaaattc attgtttcgg ctaaatcaag aaaaacttcg aatttatgga
    27781 tatccatcat attcctccta cttattccaa taaagaatac tttaacacaa aaaatgaatt
    27841 ggtgtaatct tctctgtctg ttacaatctt tcttgcagcg aaagcaataa ttacagaaat
    27901 ttttctgatt tttttcgctt cgtagaaaaa gagaggagtt ttttgatgcc aactggagtt
    27961 ttgatcaatg taggttccgt tttgtttggc ggactaattg gcggattagt aggaaataaa
    28021 ttaagtgaac attttaaagc acagctgacg atggtttttg gtgtgtgttc gatggggatg
    28081 ggaatctatt ccattgcgcc gatgaaaaat atgccggctg ttatttttgc tttagtgata
    28141 ggaacagcga ttggtttgat tgttcattta ggtaatggga taaataaggg ggctgcgctg
    28201 atgcaagtac ctatttctaa aatcttccct agtgaaaagc ttggtatgac ccacgatgaa
    28261 tttatcagca cattagtgac ggtcattgtt ctattttgtg caagtggtac ggggatctat
    28321 ggaagtttag attctgggat gacaggagac agtacgattt tgatttctaa atctgtcctt
    28381 gattttttca cagcagctat ttttgcgtgt aatttagggt atgtcgtttc tgtgatagca
    28441 attccccaat tcattatttt ttatattttg ttcttattgg caaaatttat ttatccattg
    28501 actacaccag acatgatctt agattttaaa gcttgcggcg gattcttgat ggtcgctacc
    28561 ggttttagaa tgatcaacgt gaaaatgttc ccagtagctg acatgatacc tgcaatgatc
    28621 gttatcatgc cactgagctg gatgtggaca aattggatta tgccactgtt ataataaaaa
    28681 tcaaagagaa gccatttttt gctgactaaa aaggatcaaa tcttttagtc agtttttttg
    28741 tatttgacaa actgattttg aaactatatt atatgttgta taatatagat tgaaataaaa
    28801 tattacactt gagaatagaa ggtgacgtaa tgcacatcca gattccaact gttcttcttg
    28861 atggtactgt gctagcagca ttaagcaagg aagatatgta tgggtatgcc ttaacaaaaa
    28921 tcgtacaaga aagtctctct gtcagtgaat ctacactata tccggttttg agaagattga
    28981 aaaaagaagg atatcttgag acctatgatg aaccttttga aggcagaaac cgtcgatatt
    29041 actcgttgac accaatggga agtcgtcatt tagaagaaat tattgatgaa tggattgttt
    29101 ttcgagattc tttagaccgg ttattggagg agagcacaaa tgaatgaata tttgaatgaa
    29161 gttgtggatc atcttcaaga aattcctgaa gacgatcgtt ttgatttgat ccagtattat
    29221 gaggaatatt ttttagattc tggaaaaaca ttagatcaga tcattgatga atatggtaca
    29281 ccaaagcagt ttgccttaaa attaaaaatc agttactttt cagaagaaga acaagcagaa
    29341 aacgagttag tgaaaaatcc aaaaagacaa attcgcctga tttggttaat cattatcggt
    29401 ttatttgctt ctcctgtcct cattccacta gcactggggt ttatattggt tattggggga
    29461 ctattggttg ctttactagc gctcattttt agtatctatg ttttatgtat cagtatctta
    29521 ggtgttggcc tattcatgat catctcagga atcagtgtgt ttggacaatc gattctgagt
    29581 ggattattct ttatcggtgt cggtctgttc gccacaggaa gcgcagtatt tatttcgcca
    29641 ctgttgctga aaggaacaaa agggcttttt tatgtcatga tgaactttgt taaatggatg
    29701 ggacgacgtt ttattacaaa aagagatctg cattcagcgg gcgtttgaag gaggacacat
    29761 aaattgagat tgaaacattt tttgattacc ggtattggtc tgatgcttac tggtggcctc
    29821 ctagcaggtg caacttatac attaggcgct caaaagagtc tgacttggga taatggtcct
    29881 cggttgatcg atatggttac tgagacaaaa aaaatcaagg atgcaaacaa aatcgtcatc
    29941 catgcagaaa atcaaacagt ttcggtcata cgcggattgg attttgagat aaaaacgact
    30001 tatgataaga cagaaaagcc agaaataaag gagaaaaatg gcgtgttgac tgtgaatgca
    30061 gtcaaaaaat caacaggtgc aatcattagt ttagaagaca caagtgcaca aatcactatt
    30121 gttgtccctg cagatcatga attatctgaa ttgacaatcg aagggaataa tagtgcaatt
    30181 gatatcaacg aagtatcaat caaaaaagtg aatactaaga cacatgatgg ctgggtatcg
    30241 ttcaatgaat ttacaggagg aacaataact gcgaaagatg aattaggctc acttcgatta
    30301 gatgaggcca atgtggataa cttgatcgtc acaggtgaaa acagcaactt ccatctagaa
    30361 gacagtttga tcagcaaaga aggaaaagtc atcctaaacg gtggcaattt atctttgcat
    30421 gagatggaaa acagtggcta tactatccaa acgtctggtg aatcttatat tgaaaaagac
    30481 taccagccaa taacaaatac tttgttagaa caaggacaga aaaagctaaa gatcactgct
    30541 aaagacacat cgatcaatat tacgacggat caagaggaca atgaaacaga ttgatcctgt
    30601 actcaactgg atattttaag aaaaaacagc aaagatcctt ccaatctttg ctgtttttca
    30661 tcgcttaacg cacataacta tagtaaaata agaaagaaaa tatctaaaaa gaaaacaggg
    30721 tgaaagagta tatgaaggta gaagaaggtc aaagagaaaa gttaaaaaca gaaatggaaa
    30781 gattacatac ttatatcact caactaagcc aaaccttcta tgatccagac aaagaaaaag
    30841 tgatggttaa ttacccgaac aattcagaag gtcgccaatt agagcaagtg taccatgaag
    30901 ttttcaaaca tttattgacg gtgaagaaag agctggatta ttattcttta ccgattatcg
    30961 atacaggaat attgaagtat gatgggaaga aggaacgatt tatctttaaa tctgttcggg
    31021 aagatttgcc tctttcagca gggatggatc tagaggtctt ggtagaagac tattttacag
    31081 aagaaaagca ctgggttcga acaaaattgg attatttacc gcaggcagcc ggagggacac
    31141 aggcaagcgg ttggtacatc actgaagaca aagagttaga actagaaggt gtaatggcgc
    31201 gtattcgaaa aaaaaattaa aaaagtaaca ttagatattt attgaaggat aaaggagcgc
    31261 aggaagtagc atgagagaaa aaagagcatt ttatatcaat ggttatgcag ggattgtcgg
    31321 attggtcgta ttagctttag ttggattgtt tttcttctat ttaggtatgt ggcaagcgaa
    31381 agtttgggca ctttttttaa gtatttttct ttggttgatc acgttattgt tgttaagttc
    31441 ggcaactgta gtcagtccta atcaagcaaa agtaattttg ttttttggac aatatttagg
    31501 tacgattcga gaaaatggct ttttccttac gatacctttg gcacaaaaaa tgactgtttc
    31561 gttgaaagtt cggaatttca atagttctgt tttaaaagtc aatgatttgg atggaaaccc
    31621 catcgaaatc tcagcagtag tagtctttaa agtcgttgat acagcaaagg cattattcga
    31681 tgtagcgtat tatcaagatt ttgtagaaat ccaaagtgag acagccattc ggcatatcgc
    31741 tagccaatac ccgtatgata cattcaatga gaatgatttg acgcttcgag gaaacacgac
    31801 ggcagtgtct gacgagttgc aaaaagagct gcaagagcgt ttagcagtag caggtgtcga
    31861 agtaatcgaa acacgcttga accatttagc ctatgcaaca gaaatcgcta gtgccatgct
    31921 ccaacgtcaa caagcaaaag ccattttgtc tgctcgacaa accattgttg aaggagctgt
    31981 cacaatcact caaatggcct tagagcaaat cgaagatgga caagaaatca atttcaccga
    32041 tgatcggaaa gtccaattga tcaataattt acttgtctca atcattacag acaaaggaac
    32101 gcaacctgtt atcaatacag gcgacatgaa agaccgtaag tgacatactt tttgtaagat
    32161 aggaagaagg agtttaggac ggattattgt cttgaactct ttttttagtt gttttaaaga
    32221 aaatgacaaa attgaaagaa gaatgatagt tgattcgaag gcagaattgt tcgctttttt
    32281 ctataatcag tatataaagt aagagagaag gggaaaaagt gaaaaaactt ctgatcggtc
    32341 tacttgtttt catcgttgtg gtacttgcag gggtgaaaat cgcagattac gtagttatgg
    32401 gtggagaaga atactatgta caaattacga cagatggtac aaaaacagtt tcaaaatcag
    32461 actctggaca agaaacagtc aactatagat atatcctgcc tggctatacg aaagagggta
    32521 aggaaaaaga actggacttc aagggacaat tgactcgacc gcttcgtaaa ggagcatatt
    32581 taaaaatcac ctggaacaaa aataaaggtg tcacttcgta tgaagaagtc gaaaaaaaag
    32641 acgtgccgaa aacagcactg gaaaaactaa ttaaagggta gggaaagaaa tgaacaaaat
    32701 agtcgaagta cagaatgtaa caaaagtata cggaaaaaac aatgagaaaa agacgcaagc
    32761 attaagcggc atcagcttcg atgtagaaaa aggcgaattt attgggatca tgggcgcttc
    32821 tggttctggt aagtcgacac ttttgaatat tttatccaca ttagataaac caacagatgg
    32881 gcatatccga atcaatcaaa aagatgtgac cacattaaaa ggaaatcaac tagcagattt
    32941 tcgtgcgaat gagattggct ttattttcca agatttcaat ttattagaaa gcttgacagc
    33001 acaagaaaat atcgctgttc ctctttcttt acaaggcgtc agaccaaaag aaatcaagca
    33061 acgtgtccaa aaaattgcag aacgtttatc catctctcat attttggaaa gctatccttc
    33121 tgagatttcc ggtggacaaa aacaacgggt cgccgccgca cgtgcattga tcacacaacc
    33181 aacgattcta ttaggggatg agcctacagg tgcgctggat tccaaaagtg cccgggatct
    33241 tttagatacg atggacgaat tgaatacaaa agatcatgta tcgattcttc ttgtgacgca
    33301 tgatccgttt tctgcaagtt attgccaacg tattttattc atcaaggatg gcggtatcca
    33361 tcaagaagtg aaacgtggag atcaaagccg tgattccttc tatcgagaaa tactatctat
    33421 tcttggaaac ttggaacagt agggggagat tgactatgct ttggaaatta tcacttactg
    33481 ggatcaagag ccgtttaaga gactacttgg tgttattctc aggattagtt atggcatctg
    33541 ctatttttta catgtttgaa tcaatggcaa gcaacgaagc ttttttgaaa agtaatacga
    33601 tcgttgcggc tacagttatc attttccgat tcggttctgt tttactaggg atcatcacat
    33661 tcgtttatat tttatatgca aattcctttt tgatgacgat gcggcaaaaa gactatgcaa
    33721 tgtttatgat gctgggagca aaaggcagaa aaatcgcaca gatgattttt tctgaaacat
    33781 tcttagtagg gatcgcagct actttagtgg gttcagctgt cggtgtagga ttgacaagta
    33841 tcgtccaccg attattagtg gatcagttag atctcaatat ttcgcatttt acacctttta
    33901 gtattcacgg gttgttgatc actgttttgt tttttgctgt tttgttttta ttagctgctg
    33961 ttgtcaatgc tttttcgatt gtcaaaaaac cgattttagc attgattcgt gcggatcaga
    34021 caccaacaag aatcaagcag cataaattct tgtttttcct tgaagtagta ctgggaattg
    34081 cttttctagg ctgcggttac tatatgatga aacacgtggg gacctatcaa gtctttggta
    34141 taggggtagc cttagttacg atcgtattag gaacttattt cattttccat tctgtgatca
    34201 ttttcttttt atcattacta aagaaatcag aacagatttc attgaaaaaa ttgaacaatt
    34261 tcacattgtc acagttaaac tttcgtattc gtgaatatac acaaatgctc tcaatggtcg
    34321 ctatgctgtt tgccttggca ctgggcgctt tgacggtagg attaggtttt aaaaatgaaa
    34381 ttgcagactt gacagaaaac aattctggat atgatctagt gatgaataat cctcgggcag
    34441 aagatcagca aaaaatcaaa gaactttcac caacactttc tgcttcttat actcaaaaag
    34501 aagatgcggg aacgatttac tataatgcaa gtgaatttgc ggctcaacca ttgatcatga
    34561 taaaacatga agatggaaca ccgccgaaga tcacgaaaga aaaagttcct gctaaaaaaa
    34621 tgaatgaact gactgtacaa gaggaacttc gaagctatga attgccggaa cagcaagaaa
    34681 aagaaatcaa ggtagtcagt caatcagaat ttgatcaact gaacttgcca caatccactt
    34741 tacagctagt tcaggtaaaa gacttccaag caaacctgaa accaatcgaa acacttgttg
    34801 ctcaaaataa aatgaacaat ccatctttgc aaaaagtaga gtacagcaac cagaaatatg
    34861 aaatgtatga agtgtataat ggtctattct ctggttttga atttatggga ttcttcctag
    34921 gtttagcttt cttgaccatg cttgctagct gtttgatgtt caagatcttg tcaggaagca
    34981 agagtgacat tgctcgttat gaaatgcttg aaaagatagg aacacgacgc gggttgctta
    35041 aacaatcgat ccgtagagaa gtaggcgtgt tattcttagc accaggaatc ttaggtgtag
    35101 tccatgtctt attcggatta caaatgtttg gtctattcat gcaaaatcca tacaaagata
    35161 tttgggttcc gtttacgata ttcttcgtat tgtatttcat ctactatgta ctgacgacat
    35221 ggttatatac tggaatcgta ttgaaaaaga gattgtgaaa aagctgtcct gcatcaagta
    35281 ataagaacag ccaagcaaaa atagctcctc atatttttcg tttggttggg cttattaccg
    35341 cagatgcaag cttttgaaca ccgtttgttc ggaaaaagag gttgtgacaa tatttttgtc
    35401 acaacctttt tttcacggtc ttttattaga atatagtaaa ttttttctcg ttactcacgg
    35461 aataagctgt taagaaaacg gtttccatgt atactggaat cagtgcaaat gaaagaaaag
    35521 agggtgcaag gaacatggaa atcaatgaac aaaattttgg cgaaaactat cacttgatta
    35581 cgatcacgaa tcaaaatggg acatctttgt ctgtcagtga tcttggggca cgggttgttc
    35641 attttcaaac aataatcgat aatgaaaaac gagagttgat cttaggtttt gatgaagcaa
    35701 aagaatatct agaaaaagac ccttatatcg gtgcttcaat cggacgtatg gctggacgga
    35761 ttacgaatgg cacattcaaa ttagatgatg aaacgttcga agtaaaaaca gacccggaca
    35821 ctggtcattg tttacatggt ggtgcaccta gctttgaagc caagcagtgg cattatacag
    35881 tcatcaatgg tgaaaacgaa gcatcggtca ttttctatca gactagccca gatatggaaa
    35941 acggatttcc tggaacttta gatgtagaag tacggtatac gctgacgaac gatgatacat
    36001 ggcgagtgac ggtccaaggg atcagtgacc gcaaaacagt attcaatcct acaaatcatg
    36061 tctatttcaa tttaaccggt gatccagcac agtcaatcga cgaacatata ctttggttga
    36121 atagccgatt atttgctacg ctcaataaag atacaacgcc tacaggagaa gtagtttcag
    36181 taagtggcac agcatttgac ttccaacgtc ctaaaaaatt aggtgaggtc tttgccagtg
    36241 attttcgcca atcaatgata gtgggcggca tcgatcatcc atttttgttg aaaaaacaat
    36301 ctggtttact aaatgctgcg gaattgacaa gcccagatga aaaagtatcg atccaagtaa
    36361 aaacagatgc ttcaggaatc gtgattttta cagcaaattt tggagaagat ggaccggaaa
    36421 tgcgcgggaa taaattagta aatcatggcg gtatcacatt tgagactcaa gaactgccag
    36481 gagcggagcg acttgaaagt tttggagatg tcactctgga acctaaccaa gtacgcgagt
    36541 ttgtaacgga atacaaaata aatataaaga aatagaataa attaaaaagg gagtgtgaca
    36601 gtgtcacatc ccctttttaa tttattctat ttctttaaag gcagatcaag ccagaatgat
    36661 ttgtctaaac ttaacaaggt tagtacagga acagttgcag ctttaactgt acgagtagtt
    36721 gtttctggta tctgtcttgc cgtaaaattg ttccacaaat cccagattga agcgacacgg
    36781 aagatggaag aagcgttgtt gacgcgtttt atcgttgaaa attctaatcc tgtgattggc
    36841 acgccatctg ttgtccattt gattggcaca tcgaatcgct tagacatatt gaggatttca
    36901 gcgtttgctt cttcagttgt tgctgcttct tttttcggtt catcatattt tgtcaggtcg
    36961 tacgcttcga tgatcgcgtt caatttttgt gaatattggc gatctgtagc ataacgtcct
    37021 tccaaatatt tggttgcttc tttgtagtct tttgtttccg acttccaagt tggtttgtag
    37081 aaatcaggat tgccagtcag tccatttttg atcaagtcgg catagtcttc caaactttcc
    37141 ttgtaagaag gatatttacg gaattgtgcg tggatttggt agctttgtcc ggaactatct
    37201 tgttcaagtg tattgaaggt cacgctgctt cctttatatg atcctttgat accaaaaagg
    37261 ttatgatttg gttcgcttga taataagctg tttccagatc cactttcaag gatagcttga
    37321 gccatcatga ctgatgcgta gattccttct ttttgcccga tttcctgtgc atcatctgca
    37381 atctttttca agaactgatc agttgtttgg ttttgactga aatggaacga gccatctaat
    37441 ccatctaaaa tagatgagcc gcctgtcagc gaacctgaag cagcaggtaa acctgctaag
    37501 tttactcgga cagcaaaatc aggcgtgaaa tctgaaatag aagttactcg aactttatct
    37561 cctggttgag gcgcatggat aaattgtccg ttcccaatat agatacctac atggtgagta
    37621 acaccggaag aaggtcccca gaagacgagg tcgccaggtt gggcctgact tactggaatc
    37681 tgcgtacctg catattgctg ttcgcctgtc cagccaccga tataatgacc ggttgctttc
    37741 atatatacgt aataagtcaa accagaacag tcaaaagtat ttggaccttt tgctccccat
    37801 acatatggtt ttccaagatg cttgaatgct tctcgaacga ttgcttgttg gacattcgtt
    37861 gtatttgtag gcaatacagc atcaattggt gattttacaa caaaatcaga agaagcagaa
    37921 gatggattct ctataccgct ttgatttgct gtatttggac gagatgaagc attgttcgtt
    37981 ccgccattcg atgaaccatt gtttggatgg tttggttctc tctgagtatt tccattgtta
    38041 ttcgatccag atgggtttgt ttgattcgaa gaattcccgc tgttcgaatt attgttatta
    38101 ttgtttgaat tatttgaacc attattattg ttgttattac ccacatctgg tttgtttggc
    38161 gtttccggat ctggtgtact agggacttct tcactaggat cagttggttt ctctgttgaa
    38221 gtatccggtc cagctttaaa ttctgcagta atagataaat tgttcgtacc tactgtaaag
    38281 gtctttgcat cataatttac ttctttggca ccattaacag cgactgaagc aatttgttca
    38341 ccttcagctg gcgtaatagt gtaagttacc ttcgtttccg ctaataaacc ttctaccgtt
    38401 ccactttccg taatatccaa aggttgctgt tcaggggaat ccgctgtcga agcagtcagt
    38461 tggatcttac caatcaaaga aggagcaatt gtaagggaat atgtctcggc tggcttttca
    38521 ttttctgatg gatcagccgg atcaatttca gttggctcgg tcgatcctgt tgttgagtta
    38581 gttgttccag ttgggtcttc tgtaaaagaa tccgttgttt cactagtagc tgagctggat
    38641 gtagtcgtat ctgttgtgac tgtttgatca gctatttgat tatctacggc aaatacggta
    38701 ttggtcgaca aaacagacgg agcaatcagc caagtagcag ctagcaaacg tatcgttttt
    38761 ttatttttca taataaacta gtccttttcc tttcattgat tttctgtctt attcagcatt
    38821 cattagacat tttttggaac agataatcgt gtcgaaaagc tttttctttt cataaatctg
    38881 tctgtgtatt ctaaataaaa caatttgtaa ataagcaacg agcattcatt cgtttttctt
    38941 tgacgttcat tttattgcat agaccacctt tgtttgggga taaacaagtg gggataaaaa
    39001 tggttatgca tatgtaaatt ataccaaagt ttggaaagta tcacaaaaat ttataaaaat
    39061 aatgatccta aaaagaaaaa gactgaaata tgtgataaac atctcatact tcagtctttt
    39121 tcattaacta ttcataagac attaggtctt catcaaaccc gctaacgaga gtagtgatca
    39181 ttgctacgac tagactaaca gccagtcctg ctaagtacca gaaaaaagta ccggaaatga
    39241 atgcaggcaa tgtggtcaga ctaccaaata caaaagcgat cgctttcact tgggcaaatc
    39301 ccattacagc tccaccagca gctgcaccaa tgcaagcagc aacaaatggt tttttcaatg
    39361 ggatcgcaat tccgtaaaca gttggttcgg tcactcccgc aagtaaaatc gaagcaaaag
    39421 cagaaccgga gatcgaacgg gtttttgaac gtttacttcg cagaaataca cctaaagctg
    39481 caccagccat tccaaaattg gctgctcctg tcaacggaac gattcggtcg aacccataag
    39541 cagagatatt actgatcatg acagggttta cagcccattg gataccaaat attaccaaaa
    39601 tattccaacc accagcgatg attgcgccac tgatcggtcc gttaatatcc atcatccaag
    39661 taattgcggc agctaaacct tcgccaaggt aaacacccgc aggcccgaat accattaacg
    39721 tcaaaggaac cgtgataact aatgaaagta aaggtacaaa tactaattgc atattttcgc
    39781 gaatatattt tttgaggaat ttttcaacaa aagaataaaa gaaaatacct aaaatcgccg
    39841 gcatgacagt agacgtatac tgcatcagta ctacaggaat ccccagaaaa tcagtagctg
    39901 ctttgccact gtctgaaagt aaagaggtca gattcggttc aatcagtgct gcagcaatga
    39961 cagccgcaat atatccattc actttaaacg ttttggcagc agaaaaagca agaaagattg
    40021 gcagaaaata aaagacggca ttcgacgcag cagacaaaat atgataagtt ccgcttgttt
    40081 cactaagcca gccaatcgta gtcgctaaaa caaccagacc ttttaatata ccagaaccgg
    40141 caaacagcgg aatgatcggc gtaaagattt ccgatatcaa accaaatagt ttttcgatcg
    40201 gatttagctt ttctttcgga gctgaatgat cgatttgacg cgtcaattcc ttgtaagcag
    40261 gagccaatcc ctgatccatg attatttctg catatctatc gagtaaaatg aaatacttaa
    40321 tggaagggat ttgctgtttt aatttttctg cattggctac tggctgtttt ttcaatttga
    40381 tacgaagccg agtcgcacat ggaaggacag aatcaatatt gtcttttcct cccaactgtt
    40441 caatcagcat atgaatctgc tcggacagta ccatctgttc aggattcatt gtcgtttcca
    40501 ttagaagacc actccactca ctaatataat attggcgtaa ggtgtcattt cgcctgtacg
    40561 aataaatgca tgacagttat tcaactcttt tttcatttct tcatgtggga taaagctaat
    40621 cggtgtatct ggtaacaata atttgatttt ttccaatatt tccgggttca ttgtctttat
    40681 ttcttccgcc aattcaatcg attgtacctc aagttcttct aaaacgtttt ctaaaacaga
    40741 taaaaaactt ggaagaccgt ttgagacagc caaatctatt ttttcagtac caaaggggac
    40801 aggcatgcct gcatccccga tacttaattt atcaaagtgc cccatttgtg cgattactcg
    40861 tgaaatatct gaattgatta cttttccttt tttcatgttt gtttcttcct ctcattgtta
    40921 attttagact gctgattgtt ctaaagcttc gcggtaaggg atagaaggtt gcgcaccata
    40981 agactgcaca gcaacagaag aggctagatt tccataaagg atcgcttctt tcaagttact
    41041 aaggtctggc tgaagtgtgc tgcttaatgc gccaataaat gtatcacctg cggctgttgt
    41101 gtcaacggca tccactttaa aagcagggac gataccgtgt tctttttctg tatgatagaa
    41161 agcgccggca ctgcctagtg taatgattac tgttccaata cctaattcat ggagtttttc
    41221 ggctgctgcg accaaactgt tatgatctgt cactctgatt cctgtaatga tttctgtttc
    41281 tgtttcattt ggtataatga tatctgtctt ttcaagtagt tcagtaggaa tcgtttcacg
    41341 agctggtgca ggattcagga tcgttgtttt tcctgcgtct tttgcaatag aaaaagctag
    41401 gatcgtcgca tctaagctac tttcaaactg agcaataata aagtcactgt ttgtaatcag
    41461 ttgcttgttt tttaggactt cttgttcatg gaaagcatta tttgcccctg catggatcaa
    41521 gatactattt tctcctgctg cgtctaccat aatcattgct tgtccggttg tggcgccttg
    41581 gatttcagct atcccagatg tatcgatgtt ttcttttgtc agtagatcta ataactgttg
    41641 tccttcgctg tcagccccaa cgcctccaat aaaagatgtc cgtgcgcctg aacgtttggc
    41701 tgccactgct tggttggcac ctttacctcc gccagcgtga aaaatctcat gcgcatgcat
    41761 cgtttcgcct ggcttgggca tgttggttaa acgaagggta gtgtccatat taatacttcc
    41821 aattactgta accgtgttca ttttacaaac ctccaactat ctcatttatt ttgatgggaa
    41881 aattattttt taaaacgttt tagtaaaacg ttttaatagt tcgataaaaa tatagcacac
    41941 cttgaaagct atttcaaggg tgcagttgaa aatctttttt ctaatcgtac aggtaatctt
    42001 ttttcttccc attctttttc tgggaattgg atccgatcta acaataactt ggcagatgtt
    42061 tgtcccaatt cgaagattgg ttgtgcgatc gttgtcagtt tcggcttgat atactcgcac
    42121 atatctatat tatcatagcc aataatgctg tagtcttcag ggatgctttt tccagcttcc
    42181 tctaatccgc gatataatcc aaaagctaat tcatcattta aagcaaacac accagttgca
    42241 gcagaatcaa gaagttctgc tgtgatctgg tagccacctt gttttgagaa ctgtgtaggt
    42301 aagaggatca gttggtcgtg agggatttgg taaacatcaa gagcagattt aaacccctca
    42361 atccgagcgt ggacattttc cggtggattt tcaggataga caagggcgat cgtttgatgt
    42421 cctagactaa gcaagtgcat gcccgctagg taaccaccgc gaaaatcgtc tgttcgtacg
    42481 gcatcactaa atccttcaga ttttttctga tccaaaacaa tgaagggccg gccttgtttt
    42541 ttcaaatttt cgttgattgc atctgtagag acagcagaag tcgcgataat gaatccatcc
    42601 acacctcgac gtgtgagctc ggctagatat tcgatttctt tttgatgatc agaatcagca
    42661 ttacataata tcgtgacgaa attctgctta tacaagatat cctcaattcc tcgcatcagt
    42721 gtactgaaga atggattcgt gatatcagga acgagtacac caattgtttt cgtttccttg
    42781 gtaatcattt gtctagcaaa atagtcaggc tgatagccta attcttcttt ggcagctaaa
    42841 actttctgaa cagttttcgg actgaatttc tccgtatttc catttaatat caaggagaca
    42901 gttgtgattg aaacgccgga aagtttagcg acttctttga ttgtgatctt ttttttcacc
    42961 atgttcatac tcctatctaa atcctgtggt tattttccca tgaaatcaaa aagaagtaaa
    43021 tgaaaatcac gtgtgccagt acttatttgc tttgttggat agcttcgatt atttgtttcg
    43081 ttgagcgtac tcgtgcagtt ttcggaaata tcttttttat gaacaattga tgggattctt
    43141 tgtcacgatc actgcaagca tcttcagcaa gcacgatatg gtacccgtgt tgaaaggcat
    43201 ctaatgcagt agcatataca ccgtttgttg tcgctacacc gcttaaaatg atagtttcga
    43261 ttccacgccg gcgaagttga agatcaagag aagtaccaaa aaaagcactt ggattgtatt
    43321 ttgtgatagt caacatatta tctgtatctt tcaaagaatc cttcaaaagt aaatcagtga
    43381 attctggagg tacagaagca gtcattccac ccatatcagt ttgttgactc aaataaggga
    43441 aagtggagat gtctacgttc actaaaactt tcaaggcagc ggtacgtttc aatgttctta
    43501 ctaacaaatc attgtttgtc agaatagatg ctgcagtgtg tggagagagt gtaccgttat
    43561 ttacgatctc tttttgcatg tcgatcgcga caaaagcagt ttttgataaa tcaaaaatca
    43621 tattttcctt taaatcattc atgatgttcc ttctttcaaa taacaatgtt ttttatgtaa
    43681 gtaaatcata aatcgtttat ttgtcaacta aattaaagga ttcctttctt tagtctagag
    43741 aaattcagtg gtaaaataaa taagtgtgag aaaacgcatt cgatgcatag atatagcgag
    43801 aaatatcgtg aaaatggagg aatcagagtg aagtatgtcg aagtaaaaaa tgaatacaaa
    43861 cgatacaaaa tgggagaaac gaccattaca gcaaatgacg atatttcttt ttcaattgaa
    43921 aaaggcgaat tagtgattat acttggtcca agtggagcag gaaagtcaac gattcttaat
    43981 attttaggtg ggatggatac acctgatgaa ggtcagatca ttattgatga cacagatatt
    44041 gcgcaatttt cagataaaca gcttactgct taccgacgaa cagatgtagg gttcgttttc
    44101 caattctaca atctcgttcc taatctaaca gcaaaagaaa atgtggaatt ggcaacggaa
    44161 gtttctcctg atgcgcttga tcctgtagag gtattgaggc aagtgggcct agctcatcga
    44221 ttgaataact ttccgtccca attatcagga ggcgaacagc agagggtttc aattgctcgt
    44281 gcactagcta aaaatcccaa acttctttta tgtgatgaac cgacaggcgc gctggatttt
    44341 gaaacgggca agcaagtatt gaaattattg caaaacgcta gcagacaaca cggcaatacc
    44401 gttttgatca ttacacataa ttctgcttta gcgcccatcg ctgatagagt cattcacatt
    44461 aatgatgcta aagtaaggtc tgttgaatta aatgatcatc cttcatccat tgatgagatt
    44521 gtatggtagg gggattttat gaaaacaaga acatatctta aagcaggttt tcgcgaaatt
    44581 cggcaatcta aaggacgatt cattgcaatc atccttattg tcatgctagg aacactttta
    44641 tttgtaggtg tcaaaactgc tggacctgtc atgcaaaaaa cgatggatca ctatgttggt
    44701 acagcaggac tttctgattt gcaaatcgtt tctactggtg gcttgacaca aaaagatatt
    44761 gctcaagcag aaaagatccc agatgcaaaa gtagaaacag gaaaacagat ctattattcc
    44821 aatactggca aaaacgaagt gattcaaata ttttcttata acaaaaataa caagcagaac
    44881 aagctacaat taactgatgg aaaactcccg gaaaaaccaa accagcttgt attggatgaa
    44941 aaagcggaag atgaagggta taaaatcggt gatatttatc agattgattc agatgaattg
    45001 aaagaaaaag agtataccat cacgggcttt gtccgttctc cattgttcat caacaatttg
    45061 gagagaggat acgcgaacgt cggaaatggt agcgtcgatt attttgtcta tttacctgaa
    45121 tccgttttta aaacagatat ttattctgtc ttatatcttg attttacaaa cgtaaagaat
    45181 ttgaatacgt acagcaaagc ttacaaagat aaaatggagc aaaatcaaga aaaggcagaa
    45241 aagtatttac aagatcgacc cgaagaacgc ttagaagagc tgaaaaaatc ggccaacgaa
    45301 gaattagaac cggcacagca aaaaatagcg gatggcaaag cacaaacaac gcaagcaaga
    45361 acacggttag aagatgctaa aaaacagtta gcgcaacagt cagcaactat ccagcagctt
    45421 cctgaagcgc aacgaacaat cgctgttcaa acattatctc aacaagaagc tcaacttgct
    45481 gaacaagaaa ggcaattagt tgagaaagaa cgtgaactgg cctctgcaga ggaagaattg
    45541 aatcgaaatg cagaaaaaat tgaaaattta actaaaccat catacctata caatgaacgt
    45601 tcagaaaatg tcggttttca agaatttggt gatctgtctg atcgtatcgc tgcgattgcc
    45661 aatgtttttc ctgttttctt tttctttatt gccgcattga tcacctttac gacaatgaca
    45721 cgtatggtag aagaaaaccg cagggaaatc gggacattaa aggcgttagg ttatacgaaa
    45781 gttgaaatcg caaaaaaata tgcaatctat gcaagtctag cctcagggat aggtattgtt
    45841 ttaggaacga tattaggaac gaatcttttg ccaaggatca tttttgagct gtctaacgag
    45901 cggtatgata ttgggagtgc gcttattttt tatgactggc cgccgatttt acaagcagct
    45961 gccgcattct tcattgccgc atttggcgct gcaatgatcg ttttattcaa agatttaaga
    46021 gaacggcctg ctgcattgct tcaaccgaaa gcaccgaagc cagggaaacg catttttctt
    46081 gaatacatca ctccgctgtg gtcacgcctt agctttaatc aaaaaatcag ttaccgaaat
    46141 ctcttccgat ataagtcaag aatgcttatg gcgattatcg gaattgctgg atgtgccggg
    46201 ctgatggttg caggcgtggg attgaaagat tctctaagtt ctgtttcagc caaacaattt
    46261 ggaccgatca ttgactatca agcaatcgtt acattggatt catccacgga agatagtcgt
    46321 caaaaagcag cggatatgct gcagaagcaa gaaaaagtaa atgagatcct agctattcat
    46381 actcaaaccg tagaattgag aaaaaaagga catgcttcgc aaagtctgac agtgatcgta
    46441 ccaagtaaaa cagctgattt ggatcgtttt atccatttaa ctgatcttga agagaaccca
    46501 cgctccttgc ctaaaacagg aatcgctatt acgcaaaaag tagcagaact atttgactta
    46561 tctacaggag atcatatttc gctttatgat gaagatcaaa aagaatggaa agtcgaagta
    46621 aaagaaatcg tgaaaaacta tctaggtagc tttatttata tgtcccctga atattatgct
    46681 tcagttactg atcaatcgat gatggataat gcatttttgc tgcgtacaga taagatgaca
    46741 acaaaagaag aagaaatgct ttccgagaaa ctgcttgcca cagacgctgt gacaaatacg
    46801 tctttcatgt ccaaacaaat cgaaacgcaa gaagaatcaa tggcgaactt agactcggtt
    46861 gtcttaatct ttgtcgtatt atcaggactg ctggctttta tcgtcttgta taatctaact
    46921 aatatcaata tttccgagcg tgtacgcgaa ttatctacaa taaaagtcct tggatttttt
    46981 gataaagaag tcacgatgta cattgttcga gaaaatatca tctttactct tttaggaatc
    47041 atcggaggat ttggtgtagg atatatattg actgacttca tcttgcaaca agcgtctatg
    47101 gagaatgtca tctttccatt agtgatcaca tggtgggctt atgtcttatc agcaggatta
    47161 actatcgtat ttacggttat tgtgatgatt gttacccatt tcaaattaaa gcatatcgat
    47221 atgattgatg cgttgaaatc gaatgaataa aaacagaggt tgtgaaatca gcggtttgac
    47281 ctgagtatta gagaaacaaa cggcaaaata gtttttcata ttttgccgtt ttttgagcta
    47341 ataccgaagg acagctgatt gaacaccatg aatcagaggt tgtaaaaaag ccgtcctgca
    47401 tcgagcaaaa agaatactca aataaaatta gctcctcatg ttttacattt gagaagactg
    47461 attgccgtag ataaaagctt ttgaacacca tttatagaag aaacaagaat attttgctat
    47521 tttaaacaag aggatagaca aatacatgtc tgatctcttg ttttttattg ggcaacagac
    47581 ctcttagaat gtataaagat aaattttaca aacgctttcg gttcagttat aataataaat
    47641 gataacttgt atatataagt tgtggtaggt aataaatcag ttgaatggag gtaaatatcc
    47701 atgacattta aagacaaagt catttaccaa atctatccca aatcttacaa agacagtaat
    47761 ggtgatggaa ttggagattt aaaaggaatc aaagaaaaac tcccgtatct gaatgatcta
    47821 ggcatcgaca tgatttggct aaaccctatt tatccaagcc ctcaaaaaga caacggttat
    47881 gatatctctg attacacagc catcgatcct atctttggta cgatggagga attcgaacag
    47941 ctaatagccg aagcaaagaa ataccggata gaaatcatgc tcgatatggt gctgaatcac
    48001 gtttcgacag aacatgaatg gttcaaaaaa gcactagcag gggaccagca ttatcaggac
    48061 ttcttcattt taagagaaga gccaacggat tgggtatcaa aatttggtgg aagtgcttgg
    48121 tcgccatttg gagatacggg gaaatattat ttgcacttat atgatcggac acaagctgac
    48181 ttgaactggc ggaaccaagc agtaagagag gaactattca aagttgttcg tttttggatg
    48241 gaaaaagggg taaaaggatt ccgtttcgat gttatcaatg ttatcggtaa agacgaacaa
    48301 ttgaaaaata ataaagaaaa tgatggcaaa cctgaatata cggacaaacc aatcacccat
    48361 acgtatctaa aagaattgaa ccaagcaacg tttgggacgg attccactat catcacagtc
    48421 ggtgaaatga gctctacgac gatcgaaaat tgtatcttgt atacagaacc tagtagagaa
    48481 gaattatcaa tggtctttaa tttccatcat ttgaaagtcg attatgaaaa tgggaataaa
    48541 tggtctactc ctccatttga ttttgcagaa ttaaagcgac tatttcatac atggggagaa
    48601 aagatgagtg agggtaacgg ctggaatgct ctatttttta ataatcatga tcagccacgt
    48661 gcgctcaatc gatttgtagc tatcgatcag tatcgaaaac aaggagcaga gatgctagca
    48721 accatgatcc atttgaaccg tgggacgccc tatatttata tgggagaaga aatcggcatg
    48781 atcgacccag actattcatc gatttccgac tatattgacg tagaaagttt gaatgcttat
    48841 aagttactcc ttgaacaagg attcacagaa aaagaagcgt ttcgtcggat caaagcaaaa
    48901 tctcgcgata actctcgaac acccatgcaa tggtcagaca cagaacaagc aggatttact
    48961 acagggaaac cttggttaaa agttggaggc aagctagaag agattaatgt agaaaaagaa
    49021 ctatcttctg aagattctat tttgtcctat tacaagaaat tgattcggct gagaaaaaca
    49081 tatccaatcg ttgcacaagg agattatcat gcttatgaag caaatcatcc ggaagtttat
    49141 ggctttcttc gccaatttga aggacagcag ctgcttgtat taacaaattt ctatgataaa
    49201 gatacaagga tcgccatccc agaaggattc acagaagcca atattcttat cgataattat
    49261 tccgatactg ttcttcatca aagtctggag ctaaaaccat accaggcaat tgctttgctg
    49321 aaaaattaaa acaaaaacac aaaacgtcgt tcctacgagc tattctcgta agatcgacgt
    49381 tttgtgtttt atttaaaata atcttcttca gaaaatgaag agttttcata ctctccttta
    49441 tcgccataaa atttattgta gcgttgtttg aatttacgga aaataaaagt aacgagtaat
    49501 ttgactaacg tatagatagg aataccaaaa ataacgccca caattcccat tagatcaccc
    49561 atgacaagta aaacgattaa gatcgtaatc ggatggatct gtaaacgatc acccattact
    49621 cgaggaatca ccaagtcacc gtggagaagt tgtacggcaa accagacaat gacaaatttg
    49681 acagccataa aagtagagtc ttggaatgca atgatcaaac ctggaaagaa ggcgataaac
    49741 ggcccaatat atggaatgat acataacaac ccagcagaaa tagctaaaac actagcaaat
    49801 tctaatccga tcagtaagaa acaaacccag tagactgctc caaggataaa tgaagcaatg
    49861 atttgcccct ttagaaatga acccaattgt tgattagcaa tctttgtcaa atttttaaaa
    49921 tctgtacgaa atgctggtgg gacaatcgct aaaactgact gataaaattt ttgaggatct
    49981 ctcaaaagga aaaaagcgac aattggacca gtaaataaag taataaaaat agctgtaaca
    50041 gttgaaaaaa tgttgctgat ccgttgtgcg ccactttccc aataatttcc aataaatcca
    50101 gctatatcag acgtcacgtc gtcaatagaa gcgaaaaatt gattaaatga atcggcaaaa
    50161 ggtgttttct ccaaaaattg tcggagactc tcttgaaaat cttgaaacaa atctggcaaa
    50221 ctactgatca atgtctttgc ctgttcttca agaaaaggaa taagccatat gcttccaagc
    50281 cccaataaaa ataaaataat cacataaacg ataatgactg acaagttcct cgaaaggtgc
    50341 ttgctcaaac gtttgatgac tggttccaaa agataataca agatcagtgc aaacaataat
    50401 gggggcaaga tagtagcgat aatgattccg acaggcttga atataaacga gatctgatgg
    50461 aaaaaataaa tgatcagcgc aagtaagata actattccta aaacatagta agaggttttt
    50521 cctcctaaaa agcggatcaa acgattcgtt gtatctgttt cttttttcac tctttttcct
    50581 cctttatcta taacttcatt atagacaaaa gcgggtataa aaggaaaatg atagaggttg
    50641 attgcaaaaa tatcgtcaat cattcatata aactttctca tcaattaaaa taagaaaacg
    50701 cttgacagtt cttttaacca tatgataaat taaatcctgt tgctaaaacg taactattac
    50761 ggtttgcgaa aagcgaatcg gaacattcaa atgaaagaag atgagaagag gagtgtcata
    50821 aatgaaacga ttgataggta tattggccat gctggtttta gcaggtatgt taactgcttg
    50881 cggggcaagt gggaaagccg aggacagtaa agaaaaattg agcgtgatga cgacctttta
    50941 tcccatgtat gattttacaa aagcaatcgt cggggatgaa ggagaagtag agttattgat
    51001 tccagcaggg actgattccc acgattatga accttctgct aaagacatgg caaagatcca
    51061 agatacagat atctttgttt ataatgatga aaacatggaa acatgggtcc ccgcaatcca
    51121 aaaaacatta caagaaggca atgtccatac gataaaagcg acagaaggta tgcttttact
    51181 tccgggaagt gaagaaggac atgatcatga ccatgaacac ggggaagaag gccatacaca
    51241 tgagctagac ccacatgtat ggctagctcc aagtttagca atcaagcagg tagcaaacat
    51301 acgtgatcag ctgattgaag cttacccaga aaaacaggaa gtatggacaa aaaatgcagc
    51361 agcctatacc gagaaacttc aagcactcca tcagctttat caagaaacct ttaagcaagc
    51421 aaaacaaaga tcttttgtca cgcaacatgc tgcattcaac tatctagcgt tagaatatgg
    51481 attgaatcaa gtatcgattg ctggtctttc ttctagtgaa gaaccgtctg cggcgagaat
    51541 tgctgaactg aaacactttg ttaaagaaca tggaatcaac tatatttatt ttgaagaaaa
    51601 cgccaaagat agtattgcca gaacgttagc aaacgaagca ggtgtatctt tagaagtatt
    51661 gaatcctttg gaaggattga cgaatgaaca aatagaaaat ggagaaaact atctttctat
    51721 catggaagca aacctcgaag cgttgaaaaa aacgacagag acagaaaacc cgctagaaga
    51781 tactttgacc cccaaaaaag aaaagagcgt ctacaacggt tattttgaag acgaggatgt
    51841 acaagatcgc tctctttcag attgggcagg aacttggcaa acagtagata cgtatgtaga
    51901 agatgggact tttgatcctg tttttgaata taaagaaaaa ttgaatcagg ataagacagc
    51961 acaagaatat aaagaatatt atacgaaggg ctatcaaaca gatattgctt caatcaagat
    52021 cagtgagaaa gagatggcat ttacgtttaa gaatggaaca acgaaacgtt caaattatcg
    52081 ttatgtaggg aaagaaatct tgacctacga ggcaggaaac cgtggcgtaa ggtatctatt
    52141 cgaagcagaa gataaggaaa gtggcgcttt tagatatatt caattcagtg atcacacgat
    52201 tgcaccggct gactccgaac attttcattt atatgcagga aatgaaagtc aagaagtatt
    52261 gctgaaagaa atggagaatt ggccaacatt ttatccagat acaatggatg gacgtgaaat
    52321 tgcacaggaa atgcttttgc actgataggc aaaaaagaac cgaagggttt ggatcggctg
    52381 gtcatttagt cggtccaaac tattcggttc tttttatgaa atcaatttct ttaatccacg
    52441 gatagaggct gggatggtct cgccgtttgc caacgtgact tctctggttt ttttattaat
    52501 cgaccgcaca ttttgtgtat tgataacata ggatttatga caacggataa aattccgatg
    52561 cattttctcg atttctttga tcttctcata gaattgtaat tgggcatgag tcaaatggac
    52621 ttccagttta tgtggcgctc ctagcgaagt agaaaaatat tggatgtctt tgatcggtaa
    52681 aaatttgatc tcatcattaa actctatttt gaagatatct ttttggattt gggacatttg
    52741 aaaatcttcg aaaattttgc tcaggatatg ctcgacattt tcttttaaat cataaagatc
    52801 ttctttgacg atataatcag tcggttcgat gttgcttttt aagattttca tcgacatttc
    52861 cgtatgggaa gtcacataga ttatttttcc taaaggatct aattcacgga tcaatttacc
    52921 gatcgctaca ccatccattt cactgtcttc tagttcgata tctaaaaagt aaataccaaa
    52981 agaagaagtt ctgatcttgg ctgcattgag aagttcttcc ggatcagagg tagaaatatg
    53041 gacataactg tctaagtttt caatcatgat tctatttttg atcaccgttg ataaaacttc
    53101 taattgtttt ggatcgtctt cacaaatata aatgggaatc atatcattac tcctttattt
    53161 tatttgtata taaatcgttt gagaaaaacg ctggttttca attgatgttt caaggaaaag
    53221 ataaggattg gtctttgtca attcatccaa gataaacaag ccaaggcctt cgttttttgg
    53281 atttgttttt gttgagaacc ctttttgttt caactggttt aacggtaatg tatttgttgt
    53341 tgtattgatc acacgaatca tcacggaatg attcttcttg agtatggtca attcgatttt
    53401 tttcttcttt gcagcactag ctccttcaat cgcattgtcc aagataatac caagcatacg
    53461 tacaaggttt accgtatgtt tcgtatccag ttcgattggc tcaggaaaat gaagctggac
    53521 gatcaaccct ttttcctgtg ccatcatgag ttttaatgac agtaaactac ggatctcagg
    53581 aactttcata ttatccaaca tacttagatt ggccggaaaa aggttcatca tctggcgtgt
    53641 aggtaatatc gtttgatcat aataagaccg taatccttct aagtcgcctt ctgaaatata
    53701 gctgtgaaga gaaaaaagca gattttggta atcatgtttg aattctctca agtcttgata
    53761 gtttttttct agatctttga tataatcctg ttgcatcctg acttgttgct ctaataactg
    53821 atcagctaat ttcttattag agattttcca ataataaacc aagatgatca ggccaacaca
    53881 cagatataga atgaaaaaac tcgtattcaa agctaagaca tcaggtgttt caccagaaaa
    53941 acgggtataa aaaataatga tatagtatgt aaataatatc aatgtcccga tcgtaccgat
    54001 catacggcgg tccacagtgt gaaaccaagt ctctaacgat ttttttaaac aaaaagctaa
    54061 taaagcagat aaaaaagcgg ataagacaat gtgaaaatac tgcaatgaat ctcctggttc
    54121 aataaccgaa gatttcaaaa caaaaaaatc gccgatgctt gttaagtgat ctcctaaaag
    54181 cgacgtcaat aacccaaaag gaagcgcgta aaccaattgt tgacgcgaag tcgaaaagaa
    54241 gaaaaaagta agcatcagca ttcctatagc aattagagca gtaaaaatcc ctaaaatcga
    54301 atagacccat ccaatcaaaa tacaagaaat cagaatgact cccgcaaaca gatatttgta
    54361 tcggatgtga tggtcaatca ataagataca aattgtgtaa atcaaatatt gcaacgctat
    54421 ggaccataaa aacataaagt acagctccca ttgattttta ccaaattata gcacaattgg
    54481 cgtattattt ttttaatttt tcagggattt tgaattcaga actcatacca aagcagcagc
    54541 cagatacaaa aaagtcagat aagttagtta attgtttaat gattgttttt ttcatgaaag
    54601 attcctccaa aattcatcaa gtagtttgta ataggaagca acgtagctat ttctaaaaca
    54661 atcccaagta gcaaataggt agaaaagtaa gaagctgaga aaaataacgt aatgagagaa
    54721 aaaattagaa acatgctgat cgccttcttt aataatgggg gacgtttctc gggttcaatg
    54781 ggattgattg ctgtacctct tgatccatag cgaagcagta acaaaaagca gctgattaac
    54841 aaaaagacca tcattgggaa ggagatagtc aattgcagat gtttcatcac caagggaacg
    54901 ccccataaat aaagtagtgt ccacagcaga caaacgaatt cagagtcgga atgcaatcca
    54961 taagcatatc tgcggatgca gatataagaa agaaaggtga ttcctgtttc cgcccatgag
    55021 cctgtcacca gagaaaagac tagaacgacc gctagttttc caagattatt caataaaact
    55081 tctaagacaa attttacttg gacatacacc atatcttctt ccgatttgtc tccgctgaat
    55141 aaggcttcta ataatttgtt cacaacttta tctttcatct catacgtacc tccaccacaa
    55201 attttatgct aaaaaaaata aaaaacgtct tttgtttcat aaaaagtggt tttgacatca
    55261 aaaccgtcat gatctcctaa aaaaatcttc gttttccaag aaccttacca aaaaaagtga
    55321 cagttttgat acgaaaagta ctttttatga caagtttgtg ctttttcgag tgatttatgt
    55381 taaaaaatta ctgaccttat aaaaggtgat ggagggattc ttatggaaaa tgaacaattg
    55441 tttgaagtcg gcgaaacata tgcatttaaa tctgatttat ttgaatcacc aataaaagga
    55501 aaaatagaaa aaatctatga aaatagtgtg atgatacgtg tcatgaaatg cgcagtagaa
    55561 gacaatgata ccgctcataa tctgcactgg cagttagttg tacgcaaatc aagtacaata
    55621 gaagaataaa aacagataaa atgttgagag cataaagagg ttgtgagtct cccgtttagc
    55681 tctgagttac aaggaataat gttaaaaaac agcttttcat gttttatgaa tattgccttg
    55741 tgaccgaggt gttggcagga gaatactgtt tatttgaaaa aagggctgcg acaagacttt
    55801 tgtcacagcc tttattttca tgaataggag ttacttttgg ctacttttag agaagtagct
    55861 tttaaggagc agataaagtc aaggctttta tttctataaa tgaagtagta aaatgaagaa
    55921 cagattttat tacaggaagg atgccgataa ttgtgatcat tgttgcagga acgatcggtg
    55981 cagggaaaag cacactaact gaaatgcttg cccaagattt agaaacaaaa cctttttatg
    56041 agaacgtgga agataatgaa gtattgccgc tattttattc taatccagaa aagtatactt
    56101 ttttattaca gattttcttt ttgaacaaac gctttttggc aatcaaagat gctttcagcc
    56161 atgatgacaa cgtactagac cgctccatct acgaagatag tatgctgttt catttgaatg
    56221 cagatttagg gcgtgtttct gaagtagaag taaagcagta tgaaggtctt ttagaaacga
    56281 tgctgaagga gttagaagaa atttcgccac aaaagaaacc agatctactg gtttatattc
    56341 gtgtatcctt tgaaactatg ttagcgagaa tcaaaaaaag aggccgggaa tatgaacagc
    56401 tagaacaaga tcctgaactc tattcctact ataaagaact caatcgacga tacgaagagt
    56461 ggtatgaaca gtttgatata tgtcccaaaa tagtgatcga tggggacaaa tatgatttcg
    56521 tagccgatcc ggcatgtgga gaacaaatcg tacaagaaat caagatgcgg gcaaagaaaa
    56581 tgacagaaga ggcagatgcc cagtcgatcc gctacactac aaataacccg aaagcaaagg
    56641 gaatctttac aactaaataa tataaaaact aagcaaattg ctcactcgca gatatttctc
    56701 tgtgagcagc atcttgctta gtttttttga ttcattgaga tcaaatagtg aaccgattcg
    56761 tatgataaaa ttgccataaa tgaaatgtct gagtgagggc catgatcaaa aataaaatgg
    56821 aaacgatcaa aatcgaatgg gcgccaaaca gatgatgaca gaaaacaagg acaatagctc
    56881 ctgcgataaa ggcaagaacg acacttagat agtggaaaaa tcgatcaaaa tctgcttttt
    56941 ctttagaaat acaataatca tataagttcg ttgctacccc ttttaaattt ccagttgtaa
    57001 ataaattagt gtaggcacgc ccgttgattt tatcaaaagc tacccactgg atcgatgcag
    57061 taaaagcaat caaaatcgtt actaatgcgg gatgctcatg gacgggtgtc aaactaacaa
    57121 agaaaaaaat cactgcttca taatatagaa caaacaagcg ccagaaatgt ttttcttttt
    57181 ttctaaaata atcaattaga tactttgtta gaagaatccc taagaaaaag aaaagggtag
    57241 acaatacttt tttaccaaca cttagccatt ctccgtcaaa tgcttggatg atcgatagaa
    57301 tgatattgcc agtttgagca gaggcaaaag caccatattg gatataagta taactgtcca
    57361 tggctcctcc gataaatgtc agcaaaagtc ctattgtacg cccctcgtga aaggaagtct
    57421 gcattttttt catcaccttt tatgaatatt tttgtcttcc ttatcttagc ataaacgatt
    57481 gaaaaaaaag gaaaaatttt cagaaaacta aaatcatatc gcttcccatt ttcattttta
    57541 gaaaggtctg ttagtataaa gaaaaaatag acaacgaaac tttaaataac caacttgaaa
    57601 taaacaaatt caaagaagaa agatgggaag gaaatcaatc agttgaatga aaaagaaatt
    57661 ctccgattac aaaaagaatt gaaacgctgg gagaacaagt ataaaaagct tcaacaagtc
    57721 tttcggctac aagaagaaat cattgctacc tatgaagcgg cttatggcga agcacccgga
    57781 cttattgagg aagaagtaca agtaaaagaa agtgaaggaa acagctcttt ctttaaaatg
    57841 atggagaaac gttcctataa tcgcttcaat caagaacaaa aagcagctat cacatatgat
    57901 atgaagaaac atcttcgaat catagcagga gctgggagcg gcaaaacgca aacaatctgt
    57961 gcaaaagctg tttatctgat gacgcaaaaa caagtagacg aagaacgcat actaatgatc
    58021 acttttacaa ggaacgctgc aaatgaacta aaaaaacgag tagataattt cagccagaga
    58081 aaaaccgctg tccatatcgg aacattccat agtatctttt ttaggatata caatgaaatt
    58141 tgtcgaaaat ttcctgaagt agcaatgcaa ggaatacaag gagacttttc aaaggatact
    58201 gcacaaaaag tgaatgctgt tttgcaacag ctgatacgta aatataatct ttatatattt
    58261 gatcaatatg gagaaaaaac gattgcttct cggttagact attggcagaa tatgaacctt
    58321 tcagtagaag aaatggttca gttagttaaa gaaaaatatg attccattga taagaatgca
    58381 cgacagccga tatcagaacg actgtatgga ttgctcacgg aactccaaga acaaaaaaga
    58441 agccagcaat tgctagagtt caatgatgta ctccaaaatc tgaaaagcgc tttggagaat
    58501 gaggagatcc agcattatat cggccaaaaa tatgattatc tattcattga tgaatttcaa
    58561 gatactaatc cacttcaatg ggaaatcgtg aaacggatga caaaggaaaa caggatcaag
    58621 ttgattgttg ttggagatga tgatcagagt atctatggat tcagaggatc agagccagca
    58681 tacatcaaga actttgaaaa agaatatcct accaaaactc ttttcttatt aactaattat
    58741 cgttctcggg cagctattgt ccaaggagca aatagattga tcagctataa taaaaatgat
    58801 cggataccaa aggcgatgat tccagcacaa aaagaagcag gtgttatgga agcctatttg
    58861 ttttctgata ctaaagcaga aagtcagtgg ctaatcaaac aaattcagac atttattcaa
    58921 aaaaatggga aatataagga atcaatcata ttataccgat cagcttcaca aacgcagcag
    58981 cttgtccaat ctctgctgaa aacgaatatt ccttttgtac tggaagcaga tagtccatat
    59041 gaaggtatct ttggtatcaa gtctttccaa catttctatc aaaaaattgt tcattggcaa
    59101 acagcactga atctgcaaaa gaaaaatcag gcctaccagc aattgctccg gcagctgatg
    59161 gcagactgct acctgaaaaa aagtgaatgc gatcaatact tttctcctaa atatcaaaat
    59221 atagccgttg cagattatat tttgtcgata agccccaatt taaaatcgaa atctgcagaa
    59281 atccgagagt ttgaggaagc gttgcgtaaa acagaccagc atcaagaaat ctattcgctt
    59341 gttcaaagct atcttcatct gccacgtata gctaaggaaa tcgaccagag tgatcaagaa
    59401 tggatacgag aagaagtaaa gcagcatgct actttcagaa gactccaagc cttatcgcaa
    59461 gaaacccaag cgacagctaa agaattaaaa acccgcttga ttgcttacag acaaggaaaa
    59521 cttgatgcac tatgtatcca gagcattcac aaaagtaaag gtcttagtta ccgaaatgtc
    59581 tttttgattg gttgtaacga aggaagtttg ccttataacg gagcgacaga aaagaaagta
    59641 atcgacttta atgaaataaa agcagaacca gtaacgacga tagaagaaga acgaagacta
    59701 ttttatgttg cgatgactag agcaagaaat cgtctgtatc tatgtgtacc tcaaatgaaa
    59761 aattcaagaa aattgaaagt atcgagattt atcaaagaaa ccgggagtcg tgtgaaaaaa
    59821 ggaaagtgat agaagagagg gtgtgacaga agtggtcagt ttcaagaaag aagaaggaat
    59881 gtacgaaaat tgcttctcaa atttttgtga aatttcagct tattttcgaa gaagctattt
    59941 ctggaacaca gtttattcgg aaaagggagg t
//
LOCUS       DAIGSZ010000008        59334 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.008, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000008 DAIGSZ010000000
VERSION     DAIGSZ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.008"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(159..1469)
                     /locus_tag="NOB31_000512"
     CDS             complement(159..1469)
                     /locus_tag="NOB31_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HCI0972754.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1481..2899)
                     /locus_tag="NOB31_000513"
     CDS             complement(1481..2899)
                     /locus_tag="NOB31_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0972755.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3139..4707)
                     /locus_tag="NOB31_000514"
     CDS             complement(3139..4707)
                     /locus_tag="NOB31_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCI0972756.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4711..5121)
                     /locus_tag="NOB31_000515"
     CDS             complement(4711..5121)
                     /locus_tag="NOB31_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HCI0972757.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5118..6041)
                     /locus_tag="NOB31_000516"
     CDS             complement(5118..6041)
                     /locus_tag="NOB31_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HCI0972758.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6038..6916)
                     /locus_tag="NOB31_000517"
     CDS             complement(6038..6916)
                     /locus_tag="NOB31_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HCI0972759.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6903..8240)
                     /locus_tag="NOB31_000518"
     CDS             complement(6903..8240)
                     /locus_tag="NOB31_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HCI0972760.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8243..9346)
                     /locus_tag="NOB31_000519"
     CDS             complement(8243..9346)
                     /locus_tag="NOB31_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI0972761.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9420..10928)
                     /locus_tag="NOB31_000520"
     CDS             complement(9420..10928)
                     /locus_tag="NOB31_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0972762.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10894..11586)
                     /locus_tag="NOB31_000521"
     CDS             complement(10894..11586)
                     /locus_tag="NOB31_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI0972763.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11608..12582)
                     /locus_tag="NOB31_000522"
     CDS             complement(11608..12582)
                     /locus_tag="NOB31_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0972764.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12882..13754
                     /locus_tag="NOB31_000523"
     CDS             12882..13754
                     /locus_tag="NOB31_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0972765.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14212..16410)
                     /locus_tag="NOB31_000524"
     CDS             complement(14212..16410)
                     /locus_tag="NOB31_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0972766.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16642..17634
                     /locus_tag="NOB31_000525"
     CDS             16642..17634
                     /locus_tag="NOB31_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0972767.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17694..19115
                     /locus_tag="NOB31_000526"
     CDS             17694..19115
                     /locus_tag="NOB31_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HCI0972768.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19108..20607
                     /locus_tag="NOB31_000527"
     CDS             19108..20607
                     /locus_tag="NOB31_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HCI0972769.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20646..22040
                     /gene="uxaC"
                     /locus_tag="NOB31_000528"
     CDS             20646..22040
                     /gene="uxaC"
                     /locus_tag="NOB31_000528"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HCI0972770.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22199..22882
                     /locus_tag="NOB31_000529"
     CDS             22199..22882
                     /locus_tag="NOB31_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HCI0972771.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            22884..23720
                     /locus_tag="NOB31_000530"
     CDS             22884..23720
                     /locus_tag="NOB31_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCI0972772.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23731..25485
                     /locus_tag="NOB31_000531"
     CDS             23731..25485
                     /locus_tag="NOB31_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0972773.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25761..26102)
                     /locus_tag="NOB31_000532"
     CDS             complement(25761..26102)
                     /locus_tag="NOB31_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI0972774.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26170..28341)
                     /locus_tag="NOB31_000533"
     CDS             complement(26170..28341)
                     /locus_tag="NOB31_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCI0972775.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28510..29409
                     /locus_tag="NOB31_000534"
     CDS             28510..29409
                     /locus_tag="NOB31_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI0972776.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29480..30337)
                     /locus_tag="NOB31_000535"
     CDS             complement(29480..30337)
                     /locus_tag="NOB31_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0972777.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30322..33024)
                     /locus_tag="NOB31_000536"
     CDS             complement(30322..33024)
                     /locus_tag="NOB31_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HCI0972778.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33037..34326)
                     /locus_tag="NOB31_000537"
     CDS             complement(33037..34326)
                     /locus_tag="NOB31_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HCI0972779.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34476..35522
                     /locus_tag="NOB31_000538"
     CDS             34476..35522
                     /locus_tag="NOB31_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0972780.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35524..37677
                     /locus_tag="NOB31_000539"
     CDS             35524..37677
                     /locus_tag="NOB31_000539"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HCI0972781.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38139..39590)
                     /locus_tag="NOB31_000540"
     CDS             complement(38139..39590)
                     /locus_tag="NOB31_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0972782.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39587..41311)
                     /locus_tag="NOB31_000541"
     CDS             complement(39587..41311)
                     /locus_tag="NOB31_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0972783.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41304..41918)
                     /locus_tag="NOB31_000542"
     CDS             complement(41304..41918)
                     /locus_tag="NOB31_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCI0972784.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42263..43720)
                     /locus_tag="NOB31_000543"
     CDS             complement(42263..43720)
                     /locus_tag="NOB31_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0972785.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(43761..44681)
                     /locus_tag="NOB31_000544"
     CDS             complement(43761..44681)
                     /locus_tag="NOB31_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0972786.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44693..45640)
                     /locus_tag="NOB31_000545"
     CDS             complement(44693..45640)
                     /locus_tag="NOB31_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0972787.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46119..46838)
                     /locus_tag="NOB31_000546"
     CDS             complement(46119..46838)
                     /locus_tag="NOB31_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCI0972788.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(46887..48533)
                     /locus_tag="NOB31_000547"
     CDS             complement(46887..48533)
                     /locus_tag="NOB31_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI0972789.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            48712..49302
                     /locus_tag="NOB31_000548"
     CDS             48712..49302
                     /locus_tag="NOB31_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0972790.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49394..50899
                     /locus_tag="NOB31_000549"
     CDS             49394..50899
                     /locus_tag="NOB31_000549"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HCI0972791.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(50983..52335)
                     /gene="celB"
                     /locus_tag="NOB31_000550"
     CDS             complement(50983..52335)
                     /gene="celB"
                     /locus_tag="NOB31_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCI0972792.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52335..52853)
                     /locus_tag="NOB31_000551"
     CDS             complement(52335..52853)
                     /locus_tag="NOB31_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972793.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(52869..53195)
                     /locus_tag="NOB31_000552"
     CDS             complement(52869..53195)
                     /locus_tag="NOB31_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HCI0972794.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53208..55187)
                     /locus_tag="NOB31_000553"
     CDS             complement(53208..55187)
                     /locus_tag="NOB31_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI0972795.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55208..55522)
                     /locus_tag="NOB31_000554"
     CDS             complement(55208..55522)
                     /locus_tag="NOB31_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HCI0972796.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55690..55983
                     /locus_tag="NOB31_000555"
     CDS             55690..55983
                     /locus_tag="NOB31_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HCI0972797.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56061..57173)
                     /locus_tag="NOB31_000556"
     CDS             complement(56061..57173)
                     /locus_tag="NOB31_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0972798.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57560..57739
                     /locus_tag="NOB31_000557"
     CDS             57560..57739
                     /locus_tag="NOB31_000557"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972799.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            57933..58103
                     /locus_tag="NOB31_000558"
     CDS             57933..58103
                     /locus_tag="NOB31_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0972800.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58527..59267)
                     /locus_tag="NOB31_000559"
     CDS             complement(58527..59267)
                     /locus_tag="NOB31_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI0972801.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17754 a        12136 c        10379 g        19065 t
ORIGIN      
        1 acgacttagt tatcttatca cgtctaaaaa catgtgtcaa ctcttttttg gaattttcat
       61 aaaatgtttc aatgaagcgc gacaacgttg tttaatatat cattaaaaaa aataaaggtc
      121 aagctaaaat attatttaag cttgacctta ttataatttc aacgattgtc aaaagtattg
      181 tttgcagctg tgttgccagt ttctatagat aaatcacagc ttttgaaaca taagttttgt
      241 actgcttcga ttcgcccgaa ttcttttgca gttatttggc aatgagaaaa gcagacatct
      301 tctataggct tttcaggaaa tgctactaaa tcaaaagctc gggaaggaag tgagtaacct
      361 ggagaaaggc atgcctgtac gtttttgatg tgtatgtctt tgactttcgt catttgcttt
      421 gattcaggta tttcttcagc cactgcttgc caactttctg gcatttgagc aaggtcattg
      481 ctattttttc tattgtattc attatgccag tccattatcc aagaaaaagg aaattgtaca
      541 tcaatcatat tcagattttc taccctgata ttttcgatca ctccccctct ttcttttgaa
      601 gatttcattc gaataccaca gtctgactga aaaaaatcga tatcgtgaat atatacgtca
      661 ctaactccag cactaacttc gctaccaata gttacaccgt atcctgaacg gattttacat
      721 ctagcaacct cgattcttga tgattttcga ttgactcttg caccattgcc atctctgcca
      781 gacttaatag caatacaatc atcaccacag gccaaatcac attcatagac acgcacattt
      841 gttgaagaat caatatcaat cccatctgta cttggtccat cattgttgcg gatgattact
      901 ttttctacta atacatcgtt agaataagtg atttgcaagt tccaaaaacc tgatttctga
      961 aaaatcaaat cacgaacaac aacatgttct gcatgataca gtaaacaagc gcgtggacgt
     1021 ttaatagcat aatccgcaat ccaacgaagt cccttttgat cgtattcagc tcttgtcccg
     1081 cttttttgat cttttcccca atacagctcc caccaatggt ctccttgacc gtcgattatt
     1141 ccttttcctt ctataagaat atctttcgcc gagagaacat tcaaaatcgc tgctggccat
     1201 ttcatttcta cgccggctac tcgtgtatcg atttctggaa atgcttcgat atctgttctc
     1261 cccttgagga ctgcaccttc ttcaaagata agatgactct tatcttttaa aaaaagggct
     1321 ccgactaaat aaatgccttt tggaataaat acaggtaagt gttctttcgc accttgatcg
     1381 attgcttttt gcagtattat tgtatcatct tgttgagtgt cgtttgtttt aaagttcaaa
     1441 gcattgataa tccctttttt tgtccgcaat acgtttctcc ctatctttca ttgatttttt
     1501 tcaattcttc accaataaat acagtttttg aacgattcag tgggtaacct actagcaaaa
     1561 tgattgcgga tacaaataag cagaatgctg gtaacaagtt tgccatcgta taaatccttt
     1621 cttgtactaa aactgattgg atggctccac ctgttgtaga cgattggtaa ccaatgagtg
     1681 ccagcataaa tccgcctacc gctcctgcac atgcttgtcc tacttttctc gcaaaagaat
     1741 ttactccata tactgttcca tcttctctta agcctgtctt atattgatga taatcaatca
     1801 cgtcagtaat gaatgcccag accatcaaat tgaataaacc agatcctaaa gtagcgataa
     1861 ataaaagaat cagatatacc catgcatttg ttatatgaag gaaatacatc agcaagtaca
     1921 tacatgaaga agcaagtaac gcaaatacgc ttgcttcctt tttaccaaat aattttgtca
     1981 gctttgtagc aaatggtgct aaaactacta ctgttccgta agtaaataaa agagcaacag
     2041 acattgcttg tttattatgg aagtaatcat tgaataaata agtcatattc gtcccagcta
     2101 aaatctgatt gatcacaatg aaaatgtcaa caatgactaa aataatcagt gctcgattag
     2161 ctaacaaacc ttttaccaac tgagaagcag atactttttc gtttttgaca actcttactc
     2221 tttcagtagt caatttacaa gttaacatat atgcgacaaa tgctattgca gcacatccga
     2281 ttgaaatcca aaagaaatga ttccctgaaa cgacttgttg tccactcttg ttatgggtat
     2341 acattaaaat cggaatgaag aatcctgtag ttgatccgcc aatcgcagaa ccaatgcttc
     2401 ggaacgtgga caacgaggtg cggtcattag gatttgagct aattgctgct gccattgctc
     2461 catacgggat attgattgtt gagagaaaaa tcccataaac aatgtatgaa acaaaaatat
     2521 aagcaatctt caccgtcatt ggaagatgtt ggacgaatgg caaaaacaaa atgacagtca
     2581 ctaagcaaaa tggatacttc atttttctga tccaaggaat aaatcggcca gtttctgtta
     2641 actctgagac atcacataat cttccaacca tcacatcagc aaacgcatcc aaaattctcg
     2701 aaatcaagaa taacgtacct acgattgccc ctgaaacgcc aagaacattc gtataataaa
     2761 tcatcaagaa actattgact aaacctaaaa taaaacagtt acctagatca ccgaacatgt
     2821 agcctatctt atcggaaatc ccaaattcct ttttttcttt ttttattgta tttgctgtaa
     2881 cagcattttg tgaaagcatt tgaattcctc ctacctcttc tagtaaacgt tttcaaaatt
     2941 ataactcttt ttttcttgtt tttatattca caatgttggc tttttattgc attatcttga
     3001 cagataaaaa acaaaaaata atctaaaaac attgatgcat aagattgata acttttttta
     3061 cataacaata tatacaaaca aaaaaattca ctaactagtg aaaataagtt agtgaacctc
     3121 atttattaaa gaattaaatt acagatgatc ttttccatca tacttgaaaa actcaaaatc
     3181 agcataactt cctctttttt tatttagatc atgcactgct atcccgataa aatttccagt
     3241 aaaccctcct gagagtatac acatgttttt ttgcggacct actttcttcc attcttcagt
     3301 tgatacgtct ttcaaatgaa actgtgctgt ctctttcttt acagtgactt tcaaaaaagt
     3361 cttcttttct gtgagtggaa tcgtccaatc ttctatttgt gctactccgt tttctgattc
     3421 tatcatacgt aggcattttc ccttgtcctc attccaagta acataacaat aaatataatt
     3481 ggattcattt aagtacagta ccagtccagc catctgatta aaattattag gcatgtattc
     3541 aaatgctgtc tccgcatcaa aagtaaaatc cgtttgccga atagctaaca aatgatgttc
     3601 gaaggtagat tgaagagatt caccggaaat cagacgtaaa aaacctggtc tacattttgt
     3661 atcacaccaa tcagcatttg gcaaaatgcg tctggcattc cagttcttct ttagctctcc
     3721 ttcaaatgta tccataaact gatgatcttt ttcttgttgt acctcttcat ttgtctcaat
     3781 cattatttct tccatcggag ttgtctggct atctttaagt cttaaccaat cgtcggacgt
     3841 ccaatacact tcttgaatag cggtttctct tcccaaaata gccgcaccgt ttaatggtct
     3901 ggtacaaaga tatgtcatgt accatcttcc tgacggggtt tgtactaagc tcccatgtcc
     3961 tgtacattgc aatgtagaag caggtttgtc actagctgtc agcataggaa aaccaggatc
     4021 aagctcgtaa ggaccagtaa tattctttgc tcggcaaact gtaactgaat gtcctcttcc
     4081 tgtaccgcct tctgccgtca tcaaataata atacccgtta cgaaaataca aatgtggtgc
     4141 ctccgttttc gctaattctg tacctgcaaa tattttatag atgggaccat caagcttctt
     4201 cttctctgca tcatattctt gtaatacgat accgctggat ttattcggtg tgtccagacg
     4261 ataatcccat agttcattga caagccattt ttttcccgtt tcaagatcat ggaacaaaga
     4321 aggatcaaag ccgttactat ttaaataaat tggttcggac caaggacctg tgatctcaga
     4381 tgcagtgatc aaataattgt ggacatcttt aaacggacgg cctgcacttt tgacatctgt
     4441 gtaaacaaga taaaacaatc catcagcata actgatttgt ggcgcccata tacttccatt
     4501 tgtaggattt ccttgcaaag atacttgagt ggtcaaaata tccgttgtat gtgaccagtt
     4561 gactaaattt ttcgactcat atactcggat tcctggaagc cattcaaaag aggagacaat
     4621 aatgtaatac cgctctttca ctcttaatat attaggatct ggattgaatc ctcttaaaat
     4681 aggatttttc actttgatag tctgcatgat tcaggctcct tttctcattc ttactcgata
     4741 taaactgaat gccccagctg cgaaataaaa aaatgcaaaa ggaaacgcaa taaactgagt
     4801 gccaatcaac aatatgaatc ctgttataaa atacaaacca gtggcagttg ttaagtattt
     4861 tcctttagca gtcaaaaaca atgctactgc taaaaaagca agtgaaataa acaacacaac
     4921 ggcaaacaga ccagtcatgt cctgtaataa tccaaatgta ttttctaaag acaaagttga
     4981 atgatctaca gcaagcgact gataactttt tttaaactct gacgcagaca tattacttaa
     5041 agtaactgct aacccgccaa agaaaatcaa agatagactg ccaccgacca ttcctagcaa
     5101 tagttcccat tttcttttca tttctgaacc ccctgctttt ctaaatgtat ccattcaggt
     5161 cttttgatcg atgtttcata attgttatta cgttcagaga atttgacagt ctgttcattt
     5221 ttcttgtcat cccaattatc ccaaccagtt gggtgaacat gcccacctat cttacacgct
     5281 tcaaataaga catttgcata cggacgccac ggtcttccta aatagacgtt tctagtatca
     5341 ggttctgcag tcaaggtaca gctttcaaaa cgataccctg ttttttgatt tttcggcgta
     5401 gatgctgctg tgatgtatcc aggattttta ctggctaagc tatggatatg acactgatga
     5461 aaaacggcat ctgccccacc aaatatgaaa tccaccgttc cttcaatcca gcaatattca
     5521 taggtctgac gacaatactc aggattggca gaagccggtg tacaaaaagg agtaccatct
     5581 ttttgcaaat caggcaacgg acccgtgcat aaggtatcct gataaccaga tagtcgacag
     5641 ttttttaaag atacgcgatc tcctgaattg aataaagcaa cagcctgtcc taccttttct
     5701 cctggacctg ctgtattttc gatgtgaaga ttttctaata cgacattcga tccttctaag
     5761 aaaaaagtag cacttcggaa agtccctaac tggctaccgt caagatactc ctgttttgca
     5821 aaacgattac cggagataac tactgttcct gctcccacaa gtttaaaatt ggataatctg
     5881 ctttctatat attcatcata tcttccttct tttactatca agacctttgg atggctatcc
     5941 ggcaggcctg ccaaataatc gattccttct tggatagttt caaaatccgt cggggtatct
     6001 atagcattct ttccaattat cagtttgtct ttcatcctca taaatgctcc cttatgaatt
     6061 gtttccaaat atttctcatt tcttgtgttt ccatatgacc gcctgttaaa gaaaaagaag
     6121 aaaagttttc tggactaccc attgattgat actttttgtc cagccctttt ctcagcttca
     6181 gtacgccttc gtccaagcac atcgtatcgt tttttccaac taagctaaga cgagggcgcg
     6241 gagcgatttt ttcttggatt gctaacgttg tataagctgt caatagattt ggcacatagt
     6301 aataaaaccc atgatgatct aggcggcgat gtagcaaaag tatttcgatg tccacctgtg
     6361 ccgctagatc aatacaaact ttgacacgag aatccaatgc tgtcacccac cagcttaata
     6421 agcctcccat agaaagacca atcgttgcga gccgttgagt atctgtgtct tcccttgtct
     6481 ccaaataatc gatcaagctg atcacatcat aaatacgcat tccccataac gtttttcctg
     6541 ttaataaaaa ttgtttgaac aactcgcttt cagaaatacc tccgcgttct tcaaatcccc
     6601 aagcatcaat cgaccaaaca gcatatccca ttcctgtcag tacttctgca aaagatggag
     6661 aagctaagta aggagcacca tggatcaatt cacttttccc gactgaaaaa tctccgccgt
     6721 gagaatgcag gtaaaggacc ggcggaaacg gtccttcttt ttctggataa gcatagaggg
     6781 ctggtactgt ttccaattca tttaagtaca attgatagta ttcaagcata aaaccgtttt
     6841 gtttttctcg gtataatcgt tttccactag gggtatgtct gctagatgga gcacctaaaa
     6901 aatcattcaa ctgcataagc aaagttttta cgaacaacca gttcatccat attttctgat
     6961 tgatttgatt ggaatttctc aatactgatt tctttagtat tttctaatag aaatgctggt
     7021 ccctcgtgat tttcaatcga catctggtta aaggaaacct tacccgcaaa gccaatataa
     7081 aatccttgtc tgctcatttc ctctattcct gtcatcatag caggaacacc gggaactgca
     7141 tcttgggcca tcgagacatc gatattgtca aatgtgattt cttgtatgaa ttgttccgct
     7201 aatccataaa taaaacctgc agaagcatgg acattccttg ccgtgatatt cgaaaaatgg
     7261 atccttctga atgctggtgt ccgttcatct atcggataag cctttttttc ccatacatac
     7321 ggttctttcc ctcgcggacc acagaaataa taaagattca gtataaatgg acacatcaca
     7381 ttatccatga ctatattgga tactcgaata tcttcaacga tcccgcctcg acctcgtcta
     7441 gatttcaatc gtattcctcg atcagtttct tggaagatac aatttgaaat ggtaatatta
     7501 cgaatactac cactcatttc acttcctaat acgacaccgc catgtccatg gaccatcgtg
     7561 caatttgtga tcgtgatatt ttcgcaagcg atcctttcgt acgtatcttc agtccctgcc
     7621 ttgattgcaa tacagtcatc tcccacgtca atatggcaat tactaatacg cacatttttg
     7681 catgattctg gatcaattcc gtctgtattt ggtgaatccg ctgggttcaa gatcgtcaag
     7741 ttatcaaacg ttgcattact gcaaagaatc gggttgatcg tccaacttgg tgactggatc
     7801 aatttaatat ctttcacagt aattcgatga cagttatgga aactcatcaa tttaggacga
     7861 ggataagcga gattatctgg ttcatttcta aaagtatgcc accatttttt tccatttcca
     7921 tctaatgtac cgaaaccagt gacagagatg ttctctacat tttgagcata gatacaggaa
     7981 gcataaactt ttcgatggac tccttcccaa cgtgaatgaa caacaggata atcttttgga
     8041 tcgtcagaga atttcagaac cgctcctgcg cttaaatgaa gttcgacatt gctttttaaa
     8101 aataaagctc ctgttagaaa ttcacctgct ggaacaacta cggtcccgcc tccgtcactt
     8161 gctgcagcat caatggcttg ttgtattgct tcagtattca attcatcaat tgatgcgcca
     8221 aatgtcaaaa tatcatacat atttataatg cctccacttc aatcaatgct tgcaagaatg
     8281 caccaacgcc tttttgatca ttacaaataa ttggttcact gatgtagtaa gcatatgaac
     8341 catctcgctg atctgctccg cctaaccctg ctacttgaca gtttttattc aagttcagcc
     8401 agccttcttt tgtttccaga acaaattcat caagtaatcc ttgatgtgat ttcttcactt
     8461 gtggaagcca ttcttctttg ttcagcagtc ccaaacgtat tcctttagcc attgcgtaaa
     8521 caaacatact actgccggaa gcttccagat aatttccttt ccgttttgtt tctgttgtta
     8581 cttgatacca tgtcccgctg ttttcttctt gatatggaag taatgcagcc agtgtctttt
     8641 ctagaatttc tttcagcaaa gaacaatctg tttcttcatg aagtaattca taggtatctg
     8701 ctgcagccat caaataccag ccaatcgatc ggctccaaaa atgatgggat agacctgttt
     8761 ttggatcagc ccatggttgg accttctttt catcccatgc atgaatcagc aaatttgttt
     8821 ttggatcgaa tagatgttta taactgattt caaactgtct caaaacatct tggtaatctt
     8881 tttcttcact aaaattctgg ataaattcag cataaaaagg agaacccata tataagccat
     8941 ccaaccaaat ttgataagga taaatttctt tatgccaaaa agctccttcg gatgtgcgtg
     9001 gatggtttgc caactgctgg gaaaggagtt ctgctgcttt tttatatttt tcttcgcctg
     9061 tttctttgta caataaaaag aaaagctttc ctgtatttac atggtcgata ttgtattctt
     9121 caacgctgta gccacggatc gttccatctt cttgcacgaa atagtcgata ttgtctttta
     9181 tgaaatcaaa ataaattttt tcttgggttc gttcccaaag taattggaac cctttaagta
     9241 cgacgccata gtcataagac cattttcctt tataccactt ttcttcatat aagcgaggtg
     9301 ttctttccat gatacttttt gctaatttct ttgaccagtt ttccattatt tgctctcctt
     9361 taaaaattaa aataggattt gggacaaata ccaagaagta tttgtcccaa tcgtctatat
     9421 tactgtgccg ctgctttgta tgcttcctcg tactcttgtg tgattcgatc gcctccttgt
     9481 gctttccagt cttctacagc ttttttgaat ccatcttcgt caagctgtcc catgatgtat
     9541 tgcaccgtag catcaatgac gattttttca atttctgatc ctacttcatt gttcgtcggt
     9601 gaatccaatg gcacagaagg atccattaca gcaaattctt cattttcttt gatcaattga
     9661 ttagagaatt ctttttcagg gtctgtatct ttgaaagaga acgtcacttc actaggacga
     9721 gagcttgata acggttgcac ctcttgttgc caaagatcca tatcgataaa ttcgatagaa
     9781 ccatcatcat tcaattcata atgcgttcct tcgataccgc cagtcatcaa tttatacaca
     9841 tcttcttcta aaagatcatc aacaaattga agtaatttct tcaattgtgc ttcgtctttt
     9901 acttgagatt tgggaaatgc tagcaagccg ccaataccat ttccttctga ccaaacatga
     9961 taaccgccgc cttcaccatc tgagatcttg tttacaggca ctaattccat atcatcttga
    10021 ataccttgac ccatcgtctt cagattcttg atatccacca ttccagtgta gattccagtt
    10081 cttccttgtg caaattgttc ttgctgatca gtcttttggg taactgcaaa gtcttgtgcc
    10141 aaatagccat tctcaaatag atctcttgaa aaattcaaag ctttcatata ctcttctgta
    10201 tcaaattctg gagtgaattt gccattatcg tctacagccc agccatttgg tgctccaaaa
    10261 taagaagtga aaagtttaaa gctggtataa cgaatatcac taggcgcacg atcgccaaaa
    10321 ccaactgtgt cgtccacacc atttccatca ggatcgtttt ctgtaaattg tttagctact
    10381 tcataaagct catccatggt agttggaaca tctagtccta gattatccaa ccagtctttt
    10441 cgaatgacta agccagcacg agcgtagtct ttttgtatcg gtacgccgta caaggcaccg
    10501 tcgatactcg cagcttcgat tctatcttca gaaatttgac ttaaattttt atagtctttt
    10561 aaatattctg atacatccca gaatacgcct gattttaacg cattgcggac agaagagttt
    10621 ttcaacatcg caatttgaag tgtaacgata tctcctagtt catcagaagc caatgcagtt
    10681 gttaatcttt cttcttttga agcatcagga atccagttga atgtcagttc cgtatcggtt
    10741 ttttcttcga tcaagttcac aatcgtgtct gtaggcggtg aagcatgatg caaaatattt
    10801 aaccaagtga ttttagcttt tccatcttct gtctctgaag aactgttact tgaactgctg
    10861 ccgcatgcgg caagtgctag aattcctgca aaactaagac ctaattttac gagcgttgct
    10921 tttttcataa attttctcct tcactgtttt aataatattt ttgttttctt ctgttttttc
    10981 tgtatatgag ttcttccatt ccaaatggca aaatatagaa tttgctgtcc acgtgactgc
    11041 ggaaaagaag agactgccac cgataaaggt taaaacacct ggcattgttt ggatgatcat
    11101 cagataaatc cctaccatac ttaatatcaa cactaatgag taatgaagat gtgagaatcc
    11161 gaataaaaat gccattttca ttttgaaaaa atatcctttc caatcataat gagccatgat
    11221 tgggaaaata tagagtgctg agagcacata tatgaacgca gcaatataca aagcgatcct
    11281 aagataccaa ttgtgtatga aagaaagatc cacaagtaaa acaatcccga tggcgccata
    11341 tatccagctc atcagcaagg tttcacgata gttttcttta aaatatgtga agtacgtttt
    11401 cgtcaaagga aacgtttctt ttgagcgcag ccattttcta atcactgcaa ccatcgcata
    11461 cgatgcagga ccgaaagtaa aaactcccaa acctgcgatg actaaaccgc cccacagaaa
    11521 attcaaataa accaactgta aaatacgatt tagccttccg tttattttat ctaatgactg
    11581 cagcatatct ttccctctct ttctatctta gtaaacgccg tcttctccta gctttttggc
    11641 aatcttatta gctaaaatta ccataaacaa tcctacgacc cctttaaaca atcccattgc
    11701 tgtactgaaa cttaactgtc cattcttcaa tccagctgta taaatatagg tgtcgaaaat
    11761 ttctgcaacg cttcgattca atgaattcaa taacaagtac atatgctcga accctaagtc
    11821 taatgtctga ccgattttta gaatcagcaa ggtaatgatt actggacgaa ttgccggcaa
    11881 tgtaacatgc catgttttgc gtaagcgtcc tgctccatcc atttctgcag cttcatacaa
    11941 ctgtgtatcg actgcagtta tcgctgaaag gtagatgatc gtagaccagc ccaactcttt
    12001 ccagatcact tgtccgatat atactgtgcg tgtccattca ggggatgtta gaaaactgat
    12061 tttttcaaat cccattgttg caaggaattc attcaatacc cctccgtcaa cattcaaaaa
    12121 tacataagta atcgaaacaa tgattaccca agacatgaag tgagggatgt aaatgatcgt
    12181 ttgaatcccg tttttcaatc gtttgttcgt tacttcattt aatagtaaag acaaaatgat
    12241 tggcatcgga aaaaacacga agatatttaa tccgaacaag atcaacgtat ttcttaataa
    12301 tgtaaagaat gtcggttctg taaacaaacg aatgaaatgt ttgaaaccga cccaaggact
    12361 tcccattatt cctaaaaatg gttgataatc ttgaaaagca ataacgagtc cccccatagg
    12421 aagataccta aaaatcaaga aataaaggac tcccggcaga atcatcacat ataaaaattt
    12481 attcgttttg attcctgcaa ttattttttt tcgtcttctg agcttttctt cttttttcga
    12541 tagcgtcagt tgaaatggtt cttgtttctt tacactttcc ataagcccct ccttagtttt
    12601 gtgaatgttt gctgcttatg acttcatgat agataactat ctgaattacg tatataatca
    12661 tttttaccgt aagtaaaaac gcttacatag caatgatttt tgtgctatac aaaacgataa
    12721 agtgtatttt ttcacaaata aactacgcat agcaaacctt ctattttttt ctatctgaca
    12781 cttagcatag gaaatgatta tatacgtaat ctttcaccga tgataaattg aacatataga
    12841 aacagaaaca tttaatttat tttgaggagg agcctatcta tatgaaaaag aaagtctcta
    12901 taggagaaag aagttttaca cttttcaaca atacgtttct aattttgcta gctttgatct
    12961 gtatcgttcc ttttttaaat atcatcgcta catcttttgc ttctacacaa gaagtcgtcg
    13021 cgaaaaagtt tatccttttt cctactacct tttctttaga cgcgtatcgc tacattcttt
    13081 ctacgccgac catttttaga gcacttgctg tttcgattgg tgttacaggt gtcggaacga
    13141 tcgtcagtat gtgtgcaact tcactgatgg cctacggtct ttccagaaag tatttgtttg
    13201 gtcgaggttt cgtcaacttt cttgttgtat tttctatgtt gttcagcggg gggatgattc
    13261 caacgttctt agttgttcgt tctctagggc tggtcaattc ttactgggcc atgatcctgc
    13321 ctgtggctgt taatgcaatg aatatgatca ttatgagaaa ctttttccaa gccttgccgg
    13381 atagtttgga agaatcagca aaaatggatg gttgcacaga ttttggtgta tttttcaaaa
    13441 ttatgctgcc attagcgtta ccgtctattg ctactatctc gcttttttat gctgttactt
    13501 actggaacac ttatatgact gctattttgt atatcaacga ttcatctaaa tggccgatac
    13561 agattctttt acgccaaatc gtcattgtat caagtgggat gcaagcagaa agtagtgccg
    13621 ttgatgtgat tccaccagca caaacagtta aaatggctgt tatcgttatt gcaacagtgc
    13681 ctatgctgat tgtttatcct tttgttcaga aatattttgt caaaggagca ctcgtaggtt
    13741 ctgtcaaagg gtgattatgt actgaacgca aaatggtagt tgtgtcagaa gtggtcagct
    13801 tcaagaaata agaaggcatt tacgaaaatt gcttcttaaa tttttgtgaa atttcggctt
    13861 atttttcgaa gaatctactc ctggaacacc gtgtatcaga ggttgtgaaa gagacgttca
    13921 gccttgagcg atgataaaaa ctctcacaaa cattgcgacg agtaacccac aggagcaata
    13981 agaagcgatt ttgaaaaata gcttcccata tttcacaaaa ttatgcctta ttgtcgatag
    14041 cctgtctctt gaacgccatt tattcgtaaa aaagaactgt gacaagactt ttgtcacagt
    14101 tctttttgcg tgcttagcct tgaaatttaa ctatccataa atacaaatac tagggttatt
    14161 ctaacttctt ttattgcttg aatcagtcca caagaaaaac agcctcttga ttcacaaata
    14221 tttttttcga tattctcccg gcgtaatcga ttccttcttt ttaaagaaac gaataaaatt
    14281 ttgcggattt cgatattgca atctttctgc aatctctttt acggagaggt tagtctcttt
    14341 caaccatttt tttgctacct ctaaacgatg attttgaaca aaatcaccaa atttttctcc
    14401 tgtttccttt ttaaatacat tacttaaata gttagggtta taatgcaacc tatcagcgat
    14461 cacatctaaa gacagatcac gatcatattc tgtgtagacg atatgcataa tattctccga
    14521 caaattttta aattcatgat cagtgattgc ttgagagcat tctgtgattg gcagaactaa
    14581 ttgttctaaa acaagttttt ctagttcttt gggatgataa ttgttcagtg cttttacata
    14641 aatttgtttc atgttatcaa agttttttga atctactccc aataactgtc ctaattgaac
    14701 gagttcattg atcaagcgga ccgaaactac ttcccgactc aaaggatttt tattttgtgc
    14761 aaacaatgca tcaatcaatt catgtactaa attcttcact tcctgatttc cagaacgaat
    14821 ggcttcaaac aatcgatttt gttcttctat cggatatcta ataagtgttt tttcatgagc
    14881 agcaggaacg atttcctgat aaaaaataat tgaacttgga ccagtattta cacgataata
    14941 cagggcttct tttgcccgat caaccgattg cttgctttca ttcagcgttt cgaaccggtt
    15001 actgatgcct atactgatag ttaaattcaa gtattctttt acacgttttt gaatgagtcg
    15061 gcaatactcc atgacttttt tgcttgcttc tgcatcatct ttatccattc gataaatagt
    15121 ggcttgcatt tcttcattca aaacgatcgg cagcattcga ttttcctttg gcacaatttc
    15181 cgtgatcatg ttgttgatcg ctaaaagtag caaatcacgc tccccaccgt gactatcttc
    15241 taacagatcg atttgaacca aagctgtata atagcagtca ttttgagaac tataaccaaa
    15301 ttgctgcaac cgctgatcta gttctcgcct ttctactcga tttctaaata aactaagtac
    15361 aaatagcgtt tccagctgtg gcttttgggt aactaagtgt gcacttaacg cttctttttc
    15421 tcctatgatc cgactgactg attgagcgac caaatctagt tctttcccac tgaatccttt
    15481 tgatttaaga ttcagacgtt cctgtatttg agaaatcgga cgggcaaatc tgtccgaaaa
    15541 taagtaggaa agaagaccaa tgagtcctac cagtgttaaa gacactgcaa ctagcccgat
    15601 tctcagattg cggatcattg cgccaattgc actagagtca acttctaatc tgtaaatcca
    15661 attattataa tctgatttca gtactatata cgttttatct ttttctctta tcactttcag
    15721 ctgattgtaa tctagatcca cgtccgttaa tacagttggt tgctctttat tttttactgt
    15781 ctgagtagta aaaaggttgc caacttcgtt ttcaatagaa agtatgtctt ctccactttc
    15841 accaacaact tgttctattg tatgtttctc tatcgtagca attcccaatg catatttttc
    15901 tttttcaaac attggcaaag aaatcaccat ttcgattcct ttgtttttct tttgccaaaa
    15961 taaattattt ttgttattta tgtacttctg ttgatacttt tcaacttcct cttcggtcag
    16021 ttgactcaac gatccattga ttactcccca tttaccagcc aaactgacta aatcataatt
    16081 attatcatcc ataacaatcg tttctataaa atttagttct ttcctgattt cagaataagt
    16141 ggagtaatct gtatatgtca gcggatgctt gaatatgtcc gagaaatttt tggtcgaacc
    16201 atacgtagaa aacgaatatt caatcgttct aattttccat tcaacgttag ttttaacttg
    16261 cctgagcaaa ttctttttgt ctgttaaata actcgattcg atcgattcat aggtattctg
    16321 gtaaatgaat aaactaaatc ctatgacaag tacggctcct aataaaaaca tcggtaaaaa
    16381 tattttataa aatactgtac ttttcttcat tttcttcctc tcctcctttt aaaataaaag
    16441 gctttcattt ttctgtaaaa ttgatactca tctaattaaa tgagcattcc ccgctttcaa
    16501 gaatagcata attaaaaata aaaatccaag taatttttaa cgtgtgcaat cttttcatat
    16561 caaagatcta ttgacttatc gtagttatcg taatatgatg aatgcgttaa caaaaagtga
    16621 aaaagtaagg aaaatgatgg aatggtaacg atcaaagata tcgctaaagc agctggcgtt
    16681 tctcatacga cagtttctcg tgctttgaat aacagcagtt taataaaaaa tgaaacaaaa
    16741 caaaaaatac gacaactagc taaggaaatg aattattcgc caaactatag tgcaaaaggt
    16801 ttagtgaatc aaaaaaaata tctaatcgga ctatttttct caagtttgca taaaggaact
    16861 tcatcaaatt tcctagcaga ttccattgca ggcatccatt cagtattaga cacaaattac
    16921 agtttatctg ttgaaagtat cgatgttgtt gatttaacag aaatcaacct gcaacgctac
    16981 gatggactga tcgttatgag tcaaagtgat gatgatcagc ctttcatcga ctatctcaaa
    17041 gaaaaagaat ttcctttcgt tgttgtcaat cgtcacatca atgatccagc ggttatcaac
    17101 gtcactgccg atgatgcggc cggtgttatg caggcagtag attacggtat tggatgcgga
    17161 catacgaaga tcgcttatat tggcggaaag aaaaattttc gttcgacaaa agaacgggaa
    17221 aaaggggtat tgaaaagtct aaaaaaagcg agcatccctg tcaatccagc ctatttttta
    17281 acaggagatt acagcttaga aagcggcctc caaaacatgg aatacctatt atcactttct
    17341 gacctgccta ctctggtttt ttgcggcaac gacgacatag cgattggtgc attgagagct
    17401 gtacatttag ctggcctccg tgttccccag aacatttctc tgatcgggtt cgatgattct
    17461 ccagtcgtct cctatctcaa tccgccgctt accaccgtac gtaagccttt gaaagaaatg
    17521 tgtcaagaag gaacaaagct tttactagat ttgatcgaag gcaggacgat cgaacaatct
    17581 aaaattgagc tctccacctt gttgatcctt cgtgagtcga tcaattactt gtaaactaca
    17641 agtaatttta tataaaaatg ttaacgtgtg cataacacag aaaggaagtt tatatgaaaa
    17701 aactgacaaa agaattagtg aaaaaaaacg aagcacctgt aaaagttctt cagtttggtg
    17761 aaggcaattt tatgcgtgga tttattgatt ggcagattca gcagctgaat aaccaacaat
    17821 tgtttaaagg taatgttgca atcattcaac ctttagaaca aggtcttgga aatatgatga
    17881 accagcaaga taatttatat acggtcattt tacaaggact cagcaatggc gaaatcgttg
    17941 atacttccga gattatcacc gtagtagaac aaatgatcaa tccttatgat gaatgggatg
    18001 cttatctatc tctagcagaa aatgacgact tggcctatat cgtctccaat acaacagagg
    18061 caggaatcca attcgtggag actgataatt taacagatac tcccccacag agcttcccgg
    18121 gcaaactgac agccttttta taccgacgtt tcaaattaaa caaagctggc tttaccatca
    18181 ttccttgcga actgattgac agaaacggcg aacgtctaaa agaaatcatt ttacgctacg
    18241 cagaaaaatg ggatttagaa cctgcttttg ttgagtggtt agaaaaagaa aatgttttct
    18301 gttgtagttt agttgatcgc atcgtcccag gttatcctcg cgaagatgca ggtgttttca
    18361 atcaacggca taactatgaa gatcaattga tggtcaaagc agaaccattc atgctttggg
    18421 tgatcgaagg gcctaaagaa ttggagaatc aactaccatt caaacaggct ggcttgaatg
    18481 tcatcatcac agatgatatg actccttatc gtgaacgtaa ggtgcatttg cttaatggac
    18541 cgcatacagc gatggtccct cttgctttgt tggcggaatt ggaaactgta gaagaagtaa
    18601 tgaaagatcc tttattctcc gcatatgttg atcagttatt caatctagaa ttgattccta
    18661 tgctttcttt acctaaagat gaattagcca tttatgctga ccaaatcaaa gaacgtttct
    18721 tgaatccttt tgcccatcac aaattagaag cgatttcatt aaatagtgtt tcaaagttca
    18781 gcacccgtct gcttccagtg ttcaagaagt atatcgaaga acaaaatcag gtaccaccgt
    18841 taatcactgt ttcactagct gcgctacttc ttatgtatcg aggcgatcaa gtaaagccac
    18901 atgatgatga aaagacgata agcgaattta ctgatgcttg gtctgataat ggaacagcta
    18961 ttcctcgatt attgcaaaac gctgcgcttt ggggagaaga tttgtctcaa ataccgaatg
    19021 tgacagatac agttcaagaa atagctgcaa agatcgatca aaaaggtgtc cggtcagtat
    19081 tacaagaaat gaaaggaacg atggtccatg cttgaaaccc tgcaaccaac aatgaaatta
    19141 aatcgacgag acagtgtggt cgtcgcatta acccctattc caaaacaaac acaactgacg
    19201 attgatcagc aaacgatcac cactcttgaa gatatcccgc aaggtcataa gattgcattg
    19261 ggtgatttga aagctggaga caacgtgatc aaatatggct atccaatcgg tcatgtgacg
    19321 acagacgtaa ctgccggtca atggctgcac actcataatg taaaaaccaa tctttctggt
    19381 gaattggatt atcgatatga aaaagatgtc catccaagtc attacctttt tgagaaccga
    19441 acatttcaag gttacttgcg aaaaaatgga aaagtaggga ttcgtaatga tttgttttta
    19501 gtacctaccg ttgggtgtgt gaatggcatt gctgaactga tcgtcaaaca gttcaaggaa
    19561 aaacatccag atctgggaca gtttgaccat attacgattt taaagcatcc ttatggctgt
    19621 tcgcagcttg gaaaagatca tcaaaatact cgagaaattt tagcggacgc agtaaatcat
    19681 cccaatgccg gaggagtttt agtatttgga ttaggttgtg agaacaatac agttcctgaa
    19741 ttcaaaaaaa ttttaggtga atatgatgaa gaacgagtga aatttctagt ggctcaagat
    19801 gtttacgatg agatcgaaca aggtgtggct ctattagaag agcttttaac agcggcggaa
    19861 aatgaccagc gcatatcagt cccgctctct aagttgaatg tcggtttgaa atgcggcggt
    19921 tctgatggtc tatcgggaat aactgctaat cctttacttg gtgcattttc tgactacttg
    19981 attgctcaag gaggcagcac gatcttaaca gaagtgccag aaatgtttgg cgcagaacaa
    20041 gtattgatgg cacgagcgga aaatgaagaa gtttttgact caatcgttga cttgatcaat
    20101 gacttcaaac agtatttctt gtcttacggg gaaccagttt acgaaaaccc atctcctggt
    20161 aataaagcag gtgggatcac tacattagaa gataagtctt taggctgcac gcaaaaatca
    20221 ggaagctctc ctgtcgttga tgtgctacaa tatggcgaaa aaatcagaaa accagggctt
    20281 agtttattgc aagctcccgg gaatgatctt gtagctgcct ctgctcttgc ttcatccgat
    20341 tgccagttgg tcttgtttac cacaggaaga gggactccgt ttggctcata tgtcccaacg
    20401 gtcaaggtat ctacgaatac aactcttttt gaacgcaaag gtcattggat ggattttaat
    20461 gcaggcgtct tattagaaca accaatggaa gtaatcttag aatcgtttgt tcaaaaaatc
    20521 atcgctgtag ctagtggaga agaaacgaaa aatgaacaaa atgacgttcg agaaattgcc
    20581 atttttaaaa acggagtaac actttgattt tcataaaaca gtataaaaag aaagaaggaa
    20641 gatttatgtt tttatctgat gattttttat taaaagacga ttgggcgaaa aagctttacc
    20701 attcctacgc aaaaaacatg cccattattg attatcactg tcacttagat ccaaaagaaa
    20761 tttacgaaaa caacaatttc agcaatctga cagaagcttg gttaggaggc gatcattaca
    20821 aatggcgctt gatgcgagct tgcggcgtgc ctgaagaaaa aatcacagga aatgcttctg
    20881 attttgaaaa atttttagct tggtgtcaaa ccgtaccaaa aattatcgga aatccgcttt
    20941 acagttggtc acatcttgaa ttgaagcgtt tcttcggtat tgacttgttg ataaatgaag
    21001 aaaatgcaga gaaaatttgg acacaagcaa atgaaatttt ggcagctcct gattttcgcc
    21061 gtcgggaaat cgcaaaaaaa tcgaatgtag aagtgatttg tacaacagat gatcccgcag
    21121 acgacttgca ctatcatcag ttgcttgctc atgaagaacc agatttgaag gttctacctt
    21181 cattccgtcc agataaagca ctcaatattg aaaaagaagg atttaatgca tgggtcacac
    21241 tactggaaga agcagctgac caaacgatca ccacctatca agaactgata gaagtcttag
    21301 ggcagcggat agaatacttc catcaacatg gatgtcgtgt ttccgaccac gctttagaca
    21361 tcttacgcta taaagaagcg gatgaaacag tattagaaga gatttttcaa aaagcacgag
    21421 ctaacaaact attatcttca gatgaaatcg atgcttatcg tacagaaaca ctgatacatt
    21481 tgacccactt ctatcattct cataattgga cgatgcagct gcacatccat gcttatcgta
    21541 actgtaatac acaaatgttg gaaaaattag ggcccgatac cggctatgat ggaatgaatg
    21601 atctttcttt gactattcct ctgcaaaaat tattgaaccg tgcagaagaa acggatcagt
    21661 tgccaaagac gatcctttat tcattgaatc cgaatgacta tcctgcgatt ttagctttga
    21721 tgggctgttt ccaaaaagaa cagaatggaa aactgcagtt aggttctgga tggtggtaca
    21781 acgatactcg agctggtatg cgcgatcaat tgacacaatt tgctgatggt agtgctttgg
    21841 ggaattttgt cggcatgctg acagattcaa gaagtttcct gtcctacact agacatgaat
    21901 atttccgtcg tgttctttgt gaatttttag gcgaaatggt catgcgagga gaagcacctg
    21961 aagatgaaca acttttagga agtctagttc aagcgattag ttatacaaat gctaaaaatt
    22021 actttggctt ttttgcctaa ttgattaata gtaacagtaa cgaatcaaaa acaggatagt
    22081 gaaataacgg aatccgttta tccacgtttt agagaagaag acggaccaaa tttgctccgt
    22141 cttcttctct tgctgttctg cttcattgcc tataaacctt tatgaaagaa gagataacat
    22201 gcctactatc catattgccg gtgattctac tgcggcagaa aaagatgaaa acaagcgtcc
    22261 cgagacaggt tggggagaaa aaatctctgc ttatttttca cccgagatcc agatcaataa
    22321 ccaagcaaag aatggacgca gcaccaaatc atttatccag gaaggaaggt tagcccgtct
    22381 agcttcacag tttcagccga atgatttctt atttgtacaa tttggacata acgaccagaa
    22441 aatccaagaa gaaagaggta cgcttccctt cggtagctat ttaaaaaatc tgcagatatt
    22501 ttttgaatgc gcaaaaaaag cgaacgtcca aatggtctta ctgacatctg tgacgcgacg
    22561 agattactta gaaaacggaa cattgaatcc agatatactt ggagactatc caaaagcgat
    22621 gcgtgcattt gctgagaaac accatattcc tcttttagat gtgttctcaa gatcacaaga
    22681 attgttccag accttctcaa aagaagagac aaaaaaattc tacctgcatc ttatacctga
    22741 tacttgtaaa aattacccag aaggactaaa agacaatacc cactttagtc cagaaggcgc
    22801 tgataaagtt gcccgaataa ttgttgaatt gataaaagaa tcccgtctgc ctcttgctaa
    22861 ttatttacaa aaaggagttt gagatgtttc cattaaattt aggcatccgt gcccacgatt
    22921 tagatgttcg aaatcgtgaa gaaatcgttc aaaaagtatc acagcttcac ttgtcccata
    22981 tccaatttgc accacaaaaa gcatttcctg aacaacttaa attaactgac atgacacttg
    23041 ggagtgctgc ctattttggt gaatacttcc aaaaaaacaa tatcgaactt tccattttag
    23101 gatgctatat caacctatcc agcaaaaatc aagaagttcg tgcacaagca ttggcaactt
    23161 tcaaacagca aattgctctg tgctctgcct atcaagccaa gatgattgct acggaaaccg
    23221 gtagtgtctc tgtcggttac acaaaagaaa attttactga agaagcttat cagatcgcca
    23281 gaaattctat cattgaatta gtcgctcatg cagaaaattt tggcgtaact gttgctgttg
    23341 aagcagggat caatcatcca atctataact atcagttagc taaacgttta atcgatgaag
    23401 tagcttcacc aaatttaaaa atcattttag attgtgcgaa tttgatgcat aaagaaaatc
    23461 atgctgatca ggaaaaagtg atccgaggtg ccttggacaa tttacatggt tatattacag
    23521 cgcttcatct caaagactat atcatggaaa atggaaagat ccgcatggta cctgttggca
    23581 agggctgttt agatttccgc ccggtactgc attatatcaa atatgagcgt cctctaatgt
    23641 acgccactct tgaagctact cctgagattt atgttcctga agcaatagaa cacttgcagt
    23701 ttatttacca agattgttaa ggagaagatt atggaggaac gaatacagaa aagttatcaa
    23761 aaatatcatg caaatgcttt tcagacattg ctgcatcttt atcagggaaa ttattggcgt
    23821 tttgccatgt caggactctt ttttattatc aaacatcttc catcttggtt aatgccgatc
    23881 gctattgcca atgtaatcaa tgcagcttca tcgaaagatt cttctcagtt gcaggccatt
    23941 tatttcaacg cttttttgat ggcttgtctg attggtcaaa atatattgac gaattatttt
    24001 catgtaaaat accatagcac ttcgatccgt caagtagaag ctggactaag agcgaccctt
    24061 atcaagaaaa tccaagaact atctattcct tatcaaaaag aattgcaatc tggacgaatc
    24121 cagtcaaaga tcatccgtga tgtagaagct atccaaacgt tgtcctctca agtatttgtc
    24181 agcggattaa atatcgctgt caatttattc gtagctttag gtatcacgct ttataaaagt
    24241 cctgttgttt tcatgttttt cttattgact gttcctctcg ccgcattcgt tactctcttt
    24301 ttccgtaaaa ggatcagaca gtccaactca gacttcaggc aagaaatgga agagacttct
    24361 gcaaaagtga tcgaagtgat cgaattagca ccgattgctc gagctcatgg gttagaaaaa
    24421 cacgaaacaa ctcgcttaaa taagcatttt actcaaatct atgaaaaagg attccactta
    24481 gatatcctgc aatctgtttt cggatcagtc agctgggcta gttttcagat atttcagctg
    24541 atttgtttga ttttcactgg gatattagct ttacaagggc gcatccaacc cggcgatgtc
    24601 gtgatgtatc agacgtattt cacgacgatc gtcaattccg tttctggaat gatcacgctg
    24661 attcctacga tttcaaaagg catggaatct atcacttcta ttggcgaact gttgattgct
    24721 ggcgatgtag aaacttatca cggtaagaaa aaaatccaac atttggatgg aaattttcgt
    24781 tttgaggatg tttcttttct ttatccggac tcactcaaac cgattatcga tcatttttct
    24841 ctagaggtga aagctggaga aacaattgct tttgttgggc catctggctc tggaaaatct
    24901 acactcctta acttattgat tggatttatc cagccgactt caggaaaaat ttttctagat
    24961 gatcagcctt tggatgaact ggatatgcga agtgtgcgaa attatttagc cgttgttcct
    25021 caaaccactt tgttgttctc cgcttcgatc aaagagaaca tcacttatgg cttgaaaaac
    25081 gtatcaaaag aacgtttaga tgaagtcatc gaagctgcgc aactttcttc actgattgac
    25141 cagcttcctg atggtctgga taccttagta ggcgaacatg gcaacaagct gtctggtggc
    25201 caaaagcaac gtatctccat tgcacgagcg ttgatacgtc agccaaaaat cattttgcta
    25261 gatgaagcaa cctcagcttt agataaccag tcagagaaaa aaatccagca agccctgaat
    25321 tacctgacag aaacacccac tacttttatt gtggctcatc ggctttcaac gatcaaagag
    25381 gcagataaaa tcgttgtgat cgatgaagga aaaatcgttg aaataggtac ttacgaaaaa
    25441 ctgttagctc aaaaaggcta tttctaccgc ttgaaaaatg aatgacaaaa aataggagct
    25501 atgacaagac ttttgtcgta gctcctattt ctgaataaac ggtgttctcc tgccaactcc
    25561 tcggtcacaa gtcacaatag tcatcaaaca tgagaagctg ttttttgaaa ttgttccttg
    25621 taactcagag ttaaacggta ggctcacgac ctcttggtaa atggtgttca agagacagcc
    25681 tatcggcaat aagaagcaat tttgtcatcg ctcaaggccg aacgtctctt tcacaccctc
    25741 tgttgtttca taaaatagtt ttattcgctg taaaggtcgc gaactggtgt catgatgata
    25801 cggttcaagt cattgatgat tgtactgaag ccttgctctt tttgcatcaa gtcattgatt
    25861 acttcttctg attggatttt cacagccatt tcttgtgctt tcattgcatc ttcgtcgctg
    25921 aactcttgtc cactcatttg tttttcttgt aattcgattt gcatcgcttg gaagtctttg
    25981 aacagtttgt gtgcttcttc gtttgcttgt actttctcgt acgcttcttt caacgctttg
    26041 aattctggta attcacggat ctcacgttcg atttgattcg cgctatcgta gatgtttgac
    26101 atgttatgcc ctcttttctt ttagtagtta ctctctattg taacatgggg ttattcgttt
    26161 tcaaaggggc tactctcctt gatatttccg ccagaggtct ttagccgctt caccaattcc
    26221 ctgaacgcct tctttcacca tatcgccgaa gtttttcagc ccttcttttg cttgttcacc
    26281 atattgattc aagttatctt gccaatttcc agactctcca ttagaatttc ctgtgtttcc
    26341 aacttgatct gcagctacca cttgtcctcc tgtggcatag gcatctgcta cactaaatcc
    26401 tgtttttgaa gtatacggaa ggatgccttc tgccgctgat ttgaagactt tcccgacaac
    26461 atttccactt gtcccttcca aatagtgcag cttgctggat tcttcgtaac ccatccatgt
    26521 cgaaatcact acgtctggcg tgtaaccgat catccattgg tcatttgctt ttgtggcatc
    26581 gaaattagtt tctgtggttc ctgttttccc tgctatcgta taacctgcag gattcgcagc
    26641 agccgctgtt ccatttgaaa atgtaccaag aagcatgctg gtcatttcat cggctgtttc
    26701 ctttgatatg acctgttttg gttttttgtt tgtgttatcg acgatcaccg ctccagtcga
    26761 atcaacgatt ttcgtgataa gatgcggcgt atacatctga ccatcattgg caaatgcact
    26821 gtaagcaccc gccatgatca atggagatac tcctttttcc agtccaccaa gggctaagcc
    26881 ataatactta tcagattttg ctaaaggcag gccgaattct tctgctttat catatccttt
    26941 ttgtaaaccg atctcatgca aaagccatac agtaggcaaa ttcaaacttt gtgcaacagc
    27001 ttgatacatc ggtacttctc cttggtatgt cccgtcaaaa ttatgcgcat cgtaataact
    27061 ttgcggttcg tctttcaaga tactggaagg cttgtatcca gcttccagtg ctggtgtata
    27121 tacgcttaat ggtttgatcg ttgatcctgg tgaacgacgc atctgtgtag caaagctgaa
    27181 tcctctaaag acatgatctc ctcttcgtcc tactagtgct tgtacaccac ctgtattcgg
    27241 atctaaagct actgaagcag attggaccat ggcaccatct gaagcatttg ctgggaataa
    27301 tgcactgttt tgataagtag cttctaattg cttttgataa tcctgatcta aagctgtata
    27361 gattttatag cctttattca tgacatcttc ttcatcaaga ccatactcgt taactgcttc
    27421 atcgatcact gcatcaaaat aataaggata acgataacca gaatctgaat tatcgtatgt
    27481 gtcattaaga tacgcgctga tatctgtctg gctttctgct tgttcttgtt cttttgtgat
    27541 ttttccgttt tcttccatta cacttagtac tgtgtttttc cgatcattcg cattttttgg
    27601 gtgatcgatc ggattataaa taccaggacc tttcagcatt cctgccaaag tagcagcctc
    27661 agacagcgta acattcgttg catctactcc aaaatacttt ctggaagcgt cttggacacc
    27721 ccataccccg ttgccaaaat aggcattgtt aagatacatg gtcaagattt cttctttgct
    27781 gtacttcttt tcgatctcga ttgccaaaaa taattccttc gcttttcgat caaacgtttg
    27841 gtctaatgtc agatacgcat ttttggcaag ctgctgagtg atcgtacttc ctccgccccc
    27901 tgatgttccg ccagacaaga ccattcggac tgctgcacgg gcaatccctt tgatatcaaa
    27961 cccgtgatgc tcgtaaaaat tcctatcttc tgtcgagatt actgcatctt ggatataggg
    28021 agaaatcgcg tttaattcta catatgttcc tttttgggcg tacagtgtgc cagcttcttc
    28081 gtttttctta tcataaatga ctgtcgattg gcttaatcct gattttaacg tttcgacatt
    28141 tgcttgtttt gctaaaataa agaggtagat acttgtcact aagacacaga tcaaaccaat
    28201 cagcaaaatc aatttgttca catgatattt tttccagatg cgctttcgcc atcgatggaa
    28261 ttgtccgaga tatggtctga tccaacgcca aaaactgatc aaagcagctt ttatcttttc
    28321 taaaatgctt tgaaaatcca tttgcttctt ctcctgtcta tttgattcaa tcgtcttatt
    28381 ttaccatagt gaaagagtgt tttcttcctg cttaagttgt agttcaatat gtttttttac
    28441 gttagtgcaa gtagagtaac ataagaatga acagaaaaat gtaagttttt tcttaaatat
    28501 gttttaaaaa tggtacaatt agtctgcgat tgcactgaaa ggagtacact tgtgaaaatc
    28561 acgatcactt tacctatgaa ccatcctgaa acaacaattc gcgacttgct tgaaaaggaa
    28621 tggttagttc ctagaaaggt tcgacacttt ttgcgtatac gtaaaaacgt ttggatcaat
    28681 caacaacctg ctttgttcca tcatgaagta aagggcaatg accagatcac attgttattc
    28741 gaagaaacag attataatta tcaagaagtt caattaggag atgcgaagca catccgtgtt
    28801 ttatatgaag atgagcattt gattatagtg gataagcctg caggaatgaa gactcatcca
    28861 aatgaaccga cagaaaacag taccttactc aatcatttag ctgcttatct cgacactaaa
    28921 cagcaacgac cttacgttgt ccaccgcttg gacaaagaaa caagcggtgc cgttttattt
    28981 gcaaaaaatc catttgtctt gccgatactt ggaagaatgt tggaacaaaa aatgatctat
    29041 cggagatatc aagccatcgt atggggagaa attgccaaag atatgaccat caccaataaa
    29101 attggacgag atcgccatga tcggagaaaa agggtcgtag atgataaaaa tggtcagagc
    29161 gccttgacac atgtcactgt caacaaagta ctttctgaac aaacacaagt ctattgtgtt
    29221 ttggaaaccg gacgtacaca ccagatcaga gttcatttag ctcataaggg acatccgatc
    29281 gttggagacc ctctctacca aaatagaaca gctgaacgac tgatgctcca tgcattagaa
    29341 ctgcacatga tccatccatt tactcaagaa aaaatagtcg gtaaagcttt acctggatta
    29401 tgggaataga aataaaaaag aacagagtct tatcagcaga taatgataag actctgttct
    29461 ttttgtgtaa tttgtctgct tacttttgat gttcgtgttc tgctaacagc aaactaccga
    29521 taatcccact ttcattcggc agtccccaac gaacgatata ttcacttact tgaggtgttt
    29581 ccatataacc acccatcaat tcaacaaatt gctgacggat tttttgaagg agatgatcct
    29641 gattcattac cccaccgcct aaaataatct tttcaggtgc taacgtcaac gtatagttga
    29701 tcagtgcttg agcaatataa taagcctgaa tagcccaaac aggatgatct tgcggcagat
    29761 cttgcccttt gatccctgtg cgtgcctcaa tagacggtcc tgctgctaat ccttctaaac
    29821 aatctttatg ataaggacaa gtaccttcat aatggtcatc tggatggcgt ttcacccaaa
    29881 tatgtcccat ttcaggatgt gcgatccctg aaaaaatttc ttcattgatc acgacacctg
    29941 caccgattcc tgttcccacg gtaaggtaaa tacaactatt ttttccttgt gctgctcctt
    30001 gcttcaattc cccatatgca gcagcattga catccgttgt ccaagcagca ggaatattgt
    30061 agcgttcctt gattgtgcca agaaaatcga attgtgccca cccttttttg ggagttgcca
    30121 aaacgtatcc gtaattatct tttgttttgt cgataccaat cgggccgaat gagccaatcc
    30181 cgattccctt caattcataa cgatcaaaaa attcaaatac ctgatccaat gtttcttctg
    30241 gtgttgtggt agggatactt aatttttcta aaatttctcc accatctgaa accgcacaca
    30301 caaattttgt tccgcctgct tctattccgc catacattcg ttttcctcct cgaatccgat
    30361 tgtccgaatc tcataaggtt ggattattgg gacaaccgct tgcttcgttg gttcttcaag
    30421 cagattcaat atgacagttt ttccattgtc tttagttatt tccaattttt ctaaatgact
    30481 agacatattg aaacctctta ctactacttt atcactaaac ttgctgcgtt tcaaagctgt
    30541 aattgcaaac gtttcacttt ttatcgttaa atattgttgt tttgaaatca atgttccttc
    30601 atgatgtttg atttgttgag tggaaaaagg aatctgtgct gcgtatgcat gcaaataagt
    30661 agagaatttt tcttctggtc catgtagttc aatgctgtaa ttgaaccgat gctcacctag
    30721 acactgtgct tctggtgttg gaaaatatcc ccaatcgcct agttctccca cactgcgaag
    30781 tagcgtcact gcgatttgtc cgtcttctgt tacttcatat tcattcaaac caaagtttcc
    30841 gactgttaca ccgtactctt catcatgaat attgacaaat gcttgctgat gttgcggatt
    30901 cgtggggttt tcccaacttt tagacacatg gtttgggcgc ttcaccactt caaaaatact
    30961 atctgcttcg tgatgttcca catgtaactt tgtaggaaac aagacacgta agcgatgatc
    31021 tttcatctga ttgtcgagag tcgtttcaaa gtcgattttt ttactatctt ttctgattgt
    31081 catgattgtt tttatttgaa ggattcgttt ttctttggat cgttctgctt ttcgataacg
    31141 aaattccaca accatctgct gttctttttc taaacgctcg tctgcagaaa cagggatttc
    31201 catttcctgt agaatactta tttttgctat ttccggtgta tctactaata cttttacttc
    31261 agagttttct ttgttactgg ataggattgg ctgatcacag aaaggttgtt taaagatata
    31321 ctcatttcct atatcgccga tatcttcaaa aatatgcaga ttattcaact ttcgtttgtt
    31381 tttgcgatct tccattgtaa tggtaccatt tttttcaatc gtcaaatgta gagggccgtt
    31441 ttcgatgatt cgtccactct gatgaatcat tgtttccttt tcttctgctt tcgcttcccc
    31501 ttctacaagc gcgaatgttt cccaagaaaa tgctggcatg ttttctaatg gtaaagtcac
    31561 tttgatcatt cttgccatat atggcacacg gaaacggtct ttcggcaaat cataaccaaa
    31621 ttggacagtt tcttcagata aaatagctgg tatagtggcc ccactttttg tttctacatg
    31681 atacttacgt ttaggcaaat tttctaactc ttgatatagt tgttcaggta ttccttcagc
    31741 gaatcttttt ctttctaatt cgatggttat ttctgcttca ccagttttat ccattcctgc
    31801 agtatttaca atgacaaatg gaaagctgtc ttttgggaat ccggtcgtat cgattgctgc
    31861 ggtcagctgt tctaaggaat cttgtgcaag atactttcca acttcatctg ctttttcaaa
    31921 acgaggtatc atttcccgat ggacagaatc gactgaacaa ccgcaaatac tgtcgtgagg
    31981 atgattttgc attaatgtct tccaagcata atctaattga tcatggggat agtttccact
    32041 aacttcataa gccatcgtcg caagtggttc tgtaatattt tctagctgtc gctggacctt
    32101 ggtattccat tgttttaagt aaacccgagc agatgctgta ttggctaaag tataccagcc
    32161 atccgtttct tgacttgtca attctccttc tactgagcct aagtcttctg gcacatcttt
    32221 ttgaactgct tccagatagt cagtaaaatt agaatgaata aactcgtaat ctggaaacag
    32281 ttcatttgcg agatggattg cttttgatat atctttttgt accggttgat gatcaacacc
    32341 attcatcatc aataagtggt tcgtagaggc atattgttct gcatccgcta atttttgctt
    32401 ccaaaaggca agagctgctt ctttttctac tggaatctca ttcccgttgc tataccaatt
    32461 ggcaaatagc agaccaaaga ttgctgtttg atcaggtcct ttccaccaca tctctgagta
    32521 ttgggaagaa tagttttctg cttccaaaac ttgattatca aagccaattg gttttacacc
    32581 acggccaaac gctgctgctg aaataccagc ttgtttcatt aattgaggcg tctgtcccat
    32641 atttccaaat gtatcgggaa aatagcctaa catgacaggg gttccccatt tacggctttc
    32701 ttccatgcca atcagcatat ttctcacgtt cgattccgag ctgataagaa aatcatcttg
    32761 caagatataa aatggtccaa ttctcaattt tccttcattg attgcttgtt ggattgcctg
    32821 tcttttttct ggccttactt gaagatagtc atctaaaata atcgtttgcc catccaaatg
    32881 aaaactgttg aaggacggat caacttcaaa tagctctagt agatcgtcta tcaattcaat
    32941 cagtcgcatg tgatgctgtt cgtaagccat gtaccattca cgatcccagt ggctatgaga
    33001 aatgatatat actttctttt tcatttacga tacctcctac ttttctactc taatatcaaa
    33061 gtaatccatg actaattcgc aaaacatcat atttgcccaa gaaaaccatt ctctcgtata
    33121 attttcagga ttgttcacat cgaatccttc gtgcataagg tgtgttcctg cgtcagttgc
    33181 tacaagtaaa ttcaatatcc gctctttttc agatttgtct gacgttgtca ttccttccat
    33241 agctaatgca atcggccaaa cgtatttttc tggcgtatgg gaggatccaa ttccttttgc
    33301 gtactttcct tcatagaaat atggattttc tttactcaac aatgttcttc ttgtttgcag
    33361 ataatcttcc tcttgttcag aacaatatcc caagtaaggt gcggcgatca gattgggcac
    33421 attactgtca tccatgactg tggcgtttcc cattccatct acttcatatg cataaatcgt
    33481 ttgccctttt tgattaaccg ttcgtccgtg attctgaatc ccctcttgga tctctttctt
    33541 caatttctgt gtttgctgta caatttcttt atcatcgagt atcgtttgaa aaatttcttc
    33601 cacataacct aacacgacca ccgcaaacat attggatggt accagatatc cataacggca
    33661 agtatcatcg ctaggacgga aaccagacca tgtcattcct gtaaaagctg tttttgcacc
    33721 tcgcccgtca ttgatcagcg tatcttcttt tcttgtcgtg tctcgtacaa atgtataagg
    33781 agagtgttca tgatcttgct ctgttttgaa cacgtccaag atttttttga taccttcaat
    33841 aaaagattga ttgaattgat cagtttttcc tgtatttttg taaagaagat aggccaactg
    33901 tattgggtag cataaagaat caatttcata ttttctttcc cagatccaat cgttcatttt
    33961 tgtatgatct gtttggtggc cagcaccgtt agcttcttcg ttgaaggcat tcgcatatgg
    34021 atcgatattg atataaaaaa attgcttttt gactaacccg ctgatcatgt cagctaattc
    34081 ctcatcttct tttgcaatca ctaaataagg acgaacttgt gcagtagagt ctcttaacca
    34141 catcgctgga atgtctcccg tcaataaaaa ggtggttccg tcattttgct ttttgactgt
    34201 tgtcaacaga gtattggcaa atgctgctgt aaaattcttt gcccagtccg catggatatc
    34261 cccacatttt tgtgtgatat cttccataaa tttctgcacc gattttggta tatctttata
    34321 agccactaat aaaaccttct ttctatttga tatatcttta aagattatac ttcatacagc
    34381 caattatgtc tacgctttca aaaaatatct ttttatttac tttttcatcc attatggtat
    34441 tatttgaata tgatatatca ttaagaggtg tttatatgaa tcaaccattg taccagacaa
    34501 tatttaatga tttgcaaacg gctattttaa ctggtgaatt acctgtagac agccaactac
    34561 caactgaaaa agaactttca cgtacctata aagtaagcag aatcacttcc aaacgtgcat
    34621 tgactgaatt agagcaatta ggacttattt atcgcgttcg cgggaaaggc agtttcgtta
    34681 aatccgcttc tccggaacag attcttgctt ctcctacaaa aacacgacgg attctgtttc
    34741 ttcttccata tgtcgctgat ttgtctgttg gtgattttag caagggattg aaccctgtga
    34801 tgcaagataa acagattgat gtcatgatga cgacgcttga ctttctacaa aataaaacag
    34861 caaaagagct aatcaatgaa tttgacggat tgatttatta tgctcttgat acagaacaac
    34921 atcttgactt actttttgag ctttcattga aagaattccc tgtcgtcata ttagataaaa
    34981 aaatctatga gttacctttt cctaccgttc tttccgataa tttccaaggc ggtgcgcttg
    35041 ctgcctctta tttgatcgaa cagggacatt caaaaatcgc ttatttgttt ggtacgcaga
    35101 ctcatccaca atccgttcga cagcgttacc ttggttacct tgaagcattg gacaaagctg
    35161 gtttgacttt ccacacttca ctggatgaca aaagcgcgac attagatgaa ttgctttctt
    35221 atatcactaa gtatgaagta actgcttttg tttgtgaaaa cgatgttgtc gctatccaga
    35281 ccatgaatct cttgagacag catggttatc atatccctga agatttttca attatcggat
    35341 ttgatgatat ccaagcagca gctcttgttg acccgccact gacaaccatc gcacaagatt
    35401 ttgaacagtt aggtaagctt gcgggagatg ctttggtcac ttggttagag acaaaagatc
    35461 gaccatccga tagtaaattt ccagtttcat tcatcaaaag acaatcaaca aaggagaaat
    35521 aaaatgaata tcggtcaaat agatactaga catgcaacag cgaatcagcc aaatttctct
    35581 aatgggaact gccagcctta tactggcgtt ccttttggga tgaattattt tgcaccgcaa
    35641 actacggatc aaaacggcag ctggtggttt catcctgatg accgcgtttt tcaaggctac
    35701 cgtcttaccc atcaaccaag tccttggatg ggtgatttca gtcatatgct gtttacgccg
    35761 atcaatggaa aactacagga gaacaccctt ttccatgctc aaagttctta ccgcccagaa
    35821 gaaagtatat tttgcccgac tcatctgtcg atctgtcaat tacgttatgg catctgttct
    35881 acattgatac ctagcatgta tggcggaatc ttatctattg attacagcaa aaatgacagc
    35941 ggtttacttt tatcctttcc gggacgccat cagctctttg ttatagatcc ttacacagtg
    36001 gaaggaaaaa tcacacattt tgctggttca gaagatcctg atttttcttt ttattttata
    36061 ttgagatttg aatatccttt aacaattgat gagttagctg tttccaacaa aaatagcgac
    36121 tcgatcccgt tgtattttga acagacaaaa aaacaaacta tccgatttgg gacatctttt
    36181 atcagctcgg aacaagcagc ttataacctg gaactagaac aaaaccaaag caaagagact
    36241 taccttgctc acagtcaaga acaatggcag tcctattttg atcgtataca gctcacacac
    36301 catgatcaac aacaattgcg gacgttttat cataatttat atcgggtgtt tttatttcca
    36361 caaacatttt atgaaattga tcctagtggg caaaaaatcc actatgatac gactagtcga
    36421 tctataaaac ctggtgttct ctatacaaat aatgggtttt gggatacgta taaaacggtt
    36481 tatcctcttt attctttgat tgctgtagaa aaatacgaag aaatgctgga aggttttttg
    36541 aacagctata gagaaagtgg ctatttgcca aaatggctgt ctcctgatga acgtggactt
    36601 atgcctggga cattgatcga tgcggtcatt gcagatgctg ctgtaaaaga tatccgacga
    36661 gacttgatgc ctgaatttct aacggcaatg gaaaaaggtg ctacggttca aagcaaacat
    36721 ccaaattatg gacgccaagg aacagaagat tacttgacat atggctatgt tcctaatcac
    36781 taccacgaat cagtcaatca cacattagac tatgcttata gcgatttttg tattagccaa
    36841 gttgccaagg tactagaaga agaggaaatg acgaagaaat atcagcagca atcattgaac
    36901 tatcaaaata tctttgacta tgagtcagga tttatgcgtt caaaagataa agatggcaag
    36961 ttcagagaac cattttcagc taatcgttgg ggacaagatt atgcagaagg aagtgcttgg
    37021 caaagcagct ttgctgttta tcacgatttt tcaggactga tcggaaaata tggtggcagt
    37081 gagagatata aagaaaaact cattgagctg tgcaatcagc ccccaacgtt tgacccagga
    37141 ggatatggtt ttgagatcca cgaaatgagt gagatggccg cgatagaatt tggacaatta
    37201 gctatttcaa accagccaag ttttcactat ccttacttgt tcagttatat aggacaacct
    37261 gaaatggcac agccactgct taaacagttg atgactcaga ccttcgacga ttctccaatg
    37321 ggttaccctg gagatgagga caatggaagt atggccgctt ggtatatctt caatagtctg
    37381 ggattttatc ctgtcacgcc tggaaccggt gaatatgtta tcggtatgcc attaattgac
    37441 aaggctgttt tgcttttgtc aaatggaaag gaattgacga ttgaagcaac gcctaatcgg
    37501 ccgcagcaac aatttatcca taaaatcaaa cggatggaca aagaatatac gaaattatat
    37561 tttacccatc aagatttgct gaaaggcggc acgatctctt accaattagg gatcatccct
    37621 caccctaaga aatatcaagc aaaagatttg cctttttcct tatcaaacta taattaacaa
    37681 gaggttgtga aaaagctgtc ctgcatcaag taataagaac agccaagcaa aaatagatcc
    37741 gtttggttgg tcttattacc gcagatgcaa gcttttgaac accgtttatt gagaggttgt
    37801 gaaatcagcg ttctgacctg agtattagag agacaaatgg caaaatagtt cctcatattt
    37861 tgccattttt tgagctaata ccgagggtca gctgattgaa caccgtttag tggagaggtc
    37921 gtgaaaaagc tgtttagttt cgagtattaa gaaaaatttt gtgaaaatgg ctttccacat
    37981 ttttgcataa atttggctta ataccgagaa actggctttt gaactccgtt tatcgagagg
    38041 tcatgaaaaa gctgccttgc ctcaagtaat aagaacagcc caaaattaga tttctagaca
    38101 attttttata agttatttca ttacattggc tttttctttt atgattctcc actgttttct
    38161 cggtactctt taggggatct gccgacgatt ttcttgaata atttagagaa atacgtggtg
    38221 ttgttgtagc caatctcact tgctatctca ttgatgtttt gattactgtg caaaagcagt
    38281 tgtttcgctt tttccatacg taaatggttc aaataagctg aaaaactttt tttcgtttct
    38341 tttttgaaca gctgtcctag atacatgaca tttaaatgca ggttttctga cacttctttg
    38401 agtgtaagtg gttcttgata atgctggtgc aggattacga ttactttttc cacattgtca
    38461 ctgtactttt tctgtctctg atgctttttg atgaatgaca gaagtagctg ctgaagttct
    38521 tgcaccgttt ttgcctgatg gattttttcg attccttgta aatattcctc atcttccaga
    38581 tcaatcaatt cccgttgaat ctccataaac agtaaaaaac tggaatatcg tatatcttcc
    38641 ggcatcatgg ctgctaactg aaactgttca aaaaaatcag tgatcatttt ttgagcgact
    38701 tccaattgtt tattttgcag cacgcgtctg aaacttgaaa aatcgatggt ttgatctttt
    38761 gtttctgctt gtactgcgta aaaaacatgc tcgtctttat ctccataaaa ttgatgcaac
    38821 tgtagattgt ctttcgcttg ttggaatgtt tcagggattt tgtccaaaga atctgtctct
    38881 tccccgatac tgatcagcca ttcctgatca ggaaagtttt cttgaacaaa acaacagaag
    38941 ccatcaactt catctgcctc caacaacaac gtgatcaata cacggtctcc gtaatttcgt
    39001 tgatagtaaa agatttgttg ccgttcttgc aaccatctat tgataagagt atcatgagtt
    39061 cttgccagtt gaatcaatac tatcctatgc tgcttctcac ttatttgtcc tattatttct
    39121 tcttcactta tttcatccaa ttcttcattc aaccattgac tgaataacag ttcttgatag
    39181 atttcttgtt gatttttttg ttcattttgc tgatctaacc gtgttttgat tttcttgagg
    39241 ctttcaacca attcgaactt attcacgggt ttcatcaaat aattcacggc gcctaattgc
    39301 atacctcctt tcaaataatc gaattcttgg tatcctgata aaatcataaa ttcaaaatta
    39361 tgacgttctt tttgagccgc ttcaataaat tccagtccat ttatttctgg cattgtcaca
    39421 tccgttacta ctaaatcaat ctgtcgctgt tcaagtacag ctagtccttc tttggcattc
    39481 tctgctgttg ctactatttg aaagcctaaa ctttgccaat caattatctt ttttaaccca
    39541 ttcaaaatca tgtattcatc atctaccaat aacacttgat acacgctcat ccctccttga
    39601 atgtaataga aacggtcagt ccacctgtct cattattctc aagcgacata taataactac
    39661 tgccgaagct ggcacgtaaa cgttcattca cgttttgcag accgatagaa ccgtgaagtt
    39721 ccactttagg atgagacagt ttttcttcaa tctgttttag ccgtttttca gtcatccctt
    39781 ttccattatc tttgatgatg atccttaccc gtttgccttc ctgcaagact ttgacactta
    39841 gcgcattatc gaatcgagta aaatcaatac cgtgtttaaa ataattttca actaatggct
    39901 ggatcacaaa tttaggtact tcgatctttt ccaaatcagg atcgatcata aaatgatagg
    39961 ctactcgatt aggataacgc atttgataca aatagacata tttttcgcaa aagtccagtt
    40021 cttcttttaa agtgatcgtt ttctcttgat tcgtattgtt tcgaagcaaa gcggaaaacg
    40081 catacacaac atctgctaat tcttcacttc cttcgctgat tgcatacatt cggatatatt
    40141 ctaatgtatt atataaaaag tgtggattga tctgtgcttg aagcgcccgc atatgtgcgt
    40201 cttgctgttt gatttctaat ttgtagatgt cttctacaaa ctgattgatg ctatccaaca
    40261 tttcgttgat accgattgaa agttccttca gttcatattc cgtgtttgtt atgtcgatcc
    40321 gcgtctctaa attccctgct gctgtttgat ccatggcctg catgacgata gatacttgct
    40381 gtgaatatcg tttgaatgtt ttataaagaa agataagcag tatattgtct aaaataatga
    40441 taccaatgat cagcggggca agattttttc ccgtttcgat ttttacactt tttttatcta
    40501 gtacagctaa tatacgataa tcatcagaca gttcttggtg ttgaacaaaa ttgttttttt
    40561 ccagatcgtc aatcggcaat tgtgaatttt tcttcagact ctctgtgatg atcatttctt
    40621 gtctttcaaa cgtttcttta gctattttat tatcatggaa tgtgtatagt cgatttgtcg
    40681 ttccagaaat catgtataaa gagagtccat tgaatgacgt tagattttct aaaatcatat
    40741 ctagttcttt cttttgaaaa ccaataaaaa tacttcctga ctcagctcct ccttgtgtga
    40801 taggcaactt gatataaaag gcgtctagta attttggtgt cccctttttt atttccccac
    40861 ctttgttttc tctagaagat tcataatact ccggtagttg attcaacacg atatatatcg
    40921 cacttagttc ttcataattt gcgtagagat ctttgatttg atttgggaaa gaaactaatt
    40981 catcggtact gttttgctgt tcgtatacat acatcagata ctgatctatg ggttttgtta
    41041 agtaggtcgt cacattttcg atcttttcgg aattccctac aagctggttt ttgatgatcc
    41101 tactcaaggt tgttttatca ttcagcattc tgcttgtgct ttgaacggca tcacttgtca
    41161 tgttttctgc ctgtttttga ttttgttccc aagtatggat actaaaaata acggtagcag
    41221 tcatcgttac accgatcatg ataaccgcgt atttccgcaa cagacgattt agtaaggttc
    41281 cttttgaaaa tagaatccga aacttattca taactttcca actgtttatc taattcttca
    41341 cgccaatgtg ttgtcatcgt accattccaa accgtcaaaa gaccaatgac accaaacagg
    41401 atcaatcctt tgaattgcca agtcacgcct aaaattatac cgctaccaat aattattttt
    41461 agaaaagacg aaaagctgga aaaaaccgaa ataaaactta gctttagcag attaggaaca
    41521 gagatcgtat attcactatc taaaatcata ctgtattgat aagtagcaaa taggcagagc
    41581 aaggcaaaaa gtaaaataaa atcaatagct aaaaaaatga gccctttgat ttgaacagat
    41641 aaatataaat tgtaactcaa taaagcagta ccagataaaa ataaactaaa tagcagattg
    41701 cctcttaaaa aatttctttt atatatattc cagcctcttt ttattgtgat ttctttatac
    41761 tcgaatccgt acaaataaaa tagttcattg actgttttcc atgccgcacc taatccaaag
    41821 atgatcccgc cggcaaatgt atatatccag aaatacaagg ttagttttat aatgacccag
    41881 atccggataa ataactcttc caaaaccttc cctaacatat cttctcctcc aaacattaag
    41941 tttatacttt ctcattatac aaaaaaaggt tgggcaatca gcaccttgac ctgattatta
    42001 gagaaacaaa cggaaaaata gttcctcata ttttgtcgtt ttgtgagcga ataccgaggg
    42061 ttagctgatt gaacaccgtt taccaagagt ttgtgaaata gccgcttagt ttcgagtagt
    42121 aagaaaaatt ttgtgaatat ggctttccac atttttacat atatttagct taataccgag
    42181 aaactggctt ttgaacaccg tttattcgga acaagaggtt gtgacacgtc ttttgtcaca
    42241 acccctttgt ctttattcat tattattctt gtcggaactc atcatattgt ttttgcattt
    42301 ctttcaatac cttatcatag ccagccttgt ccaaagcgtc tttcaatttc ggtaatgttt
    42361 catctggatc aacagtccct gtattcaatc catctaaata ttgattcatg acattagaaa
    42421 tattacttaa ttctgttttg acactgtcag tgttgaagct gaatcctaaa atcggtgaag
    42481 tttctgcatc agcaatcgat tgatcacgtt tggcaatcat gtcatccgta atagactctt
    42541 gtgtatatag aatcttgttg tttcctgtat tccaagcaga catatgtgta tttggctgat
    42601 aaccatctag caatttgatt ttatcatctg aaccatcgac tttttcccat gcttctccct
    42661 cgatccccca aacaagccca ttcaataatt ctggatcact gttaagcagc cctagaagtt
    42721 ctactgattt ttctttattt tttgaagtat ttgatacgac aaaatttgcc atttgtgctt
    42781 gagctgtaga ttttagtgga acagtaattg cttttgagac aagttcttgt tttgctgcat
    42841 ttgtcaaaat tgtatcgcca taatcatacg gtccttgtgt ttctccacgc attagccaag
    42901 tatttccttc tagtggataa tccttattgc tcgttgcagc gtcacttgga atgagtcctt
    42961 gtttgtacca gctatgcatt gtacgtaaca gtccgatata cgtttcatta tcgtattggt
    43021 tgatgatttt cgaatcatct ccatccagat caatagcaaa tggtaacgta ttccctaaag
    43081 gataatcaaa gttcccttgg actttgaagc cttgtccaat ggcaaaagct gccgtgtttg
    43141 gttctttttc atggaattcc ttcaagactt tttctgcatc agcgtaagat tggattccat
    43201 caattgaaag atcgtattta tctagtaaag ctttgttaaa agtaagtact tgttgagcaa
    43261 agacatttcc attgactggg aaagcatata attttccatt gaccagattt cctttaatat
    43321 atgcttcatc taaatcatta taagcttttt cagcgtactt aggcgctaat tcagtcaaat
    43381 cagcaaaggc tcctttttgg gcattggaaa catagttgtt cgcaaaggcg atatcataat
    43441 tttccccgga agaaatgatg acgttcattt tcttttcgta atcgccccag ccaatgtaat
    43501 tgatattgac ttttacaccg atctcttttt cgattcgttt gtttgctact tccatcaatt
    43561 gatcgaaatt atctggttta tctccgattt gatacatctg caaagtgtcc gaattgctag
    43621 cttctgcctg gtctttagaa ccagaacctc cgcatgctgc taatgttccc aacaacaacg
    43681 ctgaaacacc tgtaaaggct agtttcttcc ataacttcat ttttcttcct cctaatttta
    43741 tgatttatat ttttgtttct ttattctttt actccgccga ttgttagacc tttgacaaaa
    43801 tgcttctgga aaaatggata gctgatcgca ataggcaacg tcgagatgac tacgatcgcc
    43861 attctggcag attctcctgg aactgaggct aatccgcctg tcaattggct tcctgctcct
    43921 gaattttgtg tcagatattg aatattactt tggattttca tcaaaagata ctgtagtgga
    43981 actagcttat catcttggat gtatagtaaa gcattgaacc agtcattcca gtaacccaat
    44041 gcggcaaata aactgattgt cgcaatacct ggaacagcta acggtaaaac gatctgaaca
    44101 aatattcgca gttcgctagc tccatcgatc cgtgccgatt caataatcga atcagagacc
    44161 gaacgtttaa agaatgtgcg catcacaata atattgaagg gactgacagc cattggcaag
    44221 atcaatgccc aaatcgtatc ttttaactga agaagatttg tcataacaag ataattggcc
    44281 accatccctg gtgagaacaa catcgtaatc aaacaaaaaa cggtaaaaaa acgacggaat
    44341 ggaaagtttg accgtgaaat cgcataagca tataaagaag tagccgtgct attgatcagt
    44401 gtacctaaaa cagtaacaag tacagtgacg aaaagcgctt ggaaaatttt atcctgcatc
    44461 tggtcgaaca agtacgtata accaaatata ctgaactttt ctggccaaaa actgtacccg
    44521 tgagtcgaca atatggactc atcggtaaaa gagatggcga taacaaatat aaatggcaaa
    44581 atacaggaaa tagcaaagag tgcaatcatt atattagaga aaaaattagc cgtcttattg
    44641 aaagagcgga cttggactct ctccactttc ttttttttca tttttttcct ccttagaata
    44701 atgcagaatc gctatcaaaa cgtcgggcga tcgtatttgt gatcatcaac aagacaaagc
    44761 cgacaactga ttggtaaagt cctgcagcag ccgtcatacc aaaatctcct gtggatgtca
    44821 ggccattgta gatatacgta tccaaaactt gagtcacatc atataatgca ccggaattcc
    44881 taggaatgtt ataaaacagg ccaaaatcag ctcggaaaat gtttcctacg gctaaaatcg
    44941 ttaaaatcgt cattagtgga ataagttgtg gtatcgtcac atgtttgatc tgctgccatt
    45001 tgctagctcc atcaaccata gcagcttcat aataagtcgg atcgattccc ataacagatg
    45061 caaagtaaat aatgctgtta taaccaatcc ctttccatgt accaatgaac accaagataa
    45121 acggccaata tttcggttca ttataccaat tgacagcttc tcctccatgt ccagtgatcc
    45181 actgattgaa tattcctttg tcaggactta aaaaagcgta aacaaagtaa ctgataatga
    45241 cccaagatag aaaataaggt agtaaggaca tcgtttgata aactttaacg agtcgtttat
    45301 ttctcaactc gctcataatg attgcaaata cgactgagat cagcagattc aaaaggataa
    45361 atgctacatt atataaaatt gtatttttag tgatgagaaa tgcttgatcc gaagaaaata
    45421 aaaatttgaa attttcccaa cccacccaag gactttccct caagctagcc aagaacccat
    45481 ctgctgaaat atgaaaattt ttgaatgcta cgacattcgc cattacaggt atgtaaaaga
    45541 aaaaaatcat ccaaagcata cccggtacag ccatcaggac aagtgcttta taacgccata
    45601 gattcataaa aaaatgattg aacccctttc gttttttcat ctaaaaaccc ctttcgattc
    45661 attcgcaacg taattatagc gctttcaata atgagaataa ataaacaaag tatagggaaa
    45721 atgaaacaaa gtataggaga ggttgtgaaa tcagcgtttt ggcctgagta ttagagaaaa
    45781 aaacgggaaa atagttcctc atattttgcc gttttttgag ctaataccga gggtcagctg
    45841 attgaacacc gtttatcaga ggttgtgaat tcagcgtttt ggcctgagta ttagggagat
    45901 cgtgtcctta ctatctaact ctgagtcaca aggaacaatg gggactgtaa caaaagtctt
    45961 gtcacagtcc cttattccga acaaacggtg ttccagaagt agcttctacg gaaataagcc
    46021 gaaatttcac aaaaaagcca tccgaaagtc agacggacaa gtctgctttt cagatggcgc
    46081 tacaactact ctgcttattc ttttagctat ccattcaatt atttttctct cacttgttct
    46141 agctcttctt tggtcatggg tcgatattgc cctttattca aatctttagg cagccaaaat
    46201 tttcccatac ggattctttt taaatataag acttcttttc ctactgcttt gaccattcgc
    46261 ttaacttggt gaaactttcc ttcatgcaaa atcagacgga taattgaagt ttctgtctct
    46321 tgatctactt gatcaatttg gagttttgcc ggcaatgtct gctcatcgcc atcaataatc
    46381 agtccttctg caaataaacg gatatcttct tctgtcatta taccgctaac ctcagctaga
    46441 tattctttct ccacatgttt tttaggtgat agtaactgat gggcaaacac cccgtcattc
    46501 gttaaaatca agaggccctc tgtgtcttta tctaatcggc cgactggaaa aagatcttcc
    46561 cgataatcct ggtcttccaa taaatcgatt acggtttgat catgattatc ctgagtagca
    46621 gaaatgactc ctgcaggttt atgcaaaatg tagtaaaaat ctttttgata cgtaatgatt
    46681 tctcctaaat aagtaaccgc atcttcgaat tcatttactt gcgctttatc gcttttcacc
    46741 acttgtccat tgacttcgat cgttcctttt ttgattaatc ctttgacttc tttgcggctg
    46801 ccaagtccca tatctgctaa aaacttatct aaacgcatgc gtttccccca tttcaaaaga
    46861 gcatcaatct agctcttctg attcacttat tttattttta atttatgtcg taaacgcgct
    46921 attcctggtc ctagtagtct ttctgccaag cggattttca aagctaaata accatacact
    46981 aaagccccta tacctgctac tacaagaatc aacaatagag actggaattt gctatcttcg
    47041 tttaaaaaag caccaaaaat catctttgtg atccacgaag ccaaaagcat aatcaaggta
    47101 agaataaaga tcagcaatgt cctgcgccag acaaaacttg gtttaaagcg ggctacttca
    47161 tggattctct ttaagatcaa ggtacaagac acagcaaatc cgatcattgt cgccaataaa
    47221 gggccgtata cttcaaataa acgaatggct gggtattgaa gaaggagttt cactagaaac
    47281 ccaataacca aataattaat tgccgccttg ttttcaaaca ttccttgcag catgttggaa
    47341 actagcatat atagtcctag gaagagtcct acaaaacttg cttggatcag tacattactt
    47401 cctagagaat ccggtgtata aaataatgta tttagcggat aggcaagtaa cataacacca
    47461 aatgtcgccg gaaacataaa aaatgaaaac aactgtaaat ttccgcttgt caattttgcc
    47521 agacctactc gatctttcaa cgtaacagct tctgtaatca acggtaaccc agtagacgcg
    47581 atcgatgttg ccaatgcaat aactaccatc gtcaacttat ctggattggc actaaaaatc
    47641 gaaaaaagat ccagtaactg tgcattggaa tactcggtgg atgcagacat gatcttcata
    47701 aaagtgaact gatcgactaa tttgaagatc gttacccctg aacccacaat aataaacgga
    47761 atcgcttctt taacggtatc taacaacaat tccttcgttg caatatttat tttgttttcg
    47821 ctgtagtgaa taaacgccga tgtatacgct tgatgtttct tcaaaaaata caaaaggaca
    47881 agaatacttg ctagcatacc gataaatgcc gcgaaagttg attgcgtgac cgccgtcaca
    47941 tagtcaccat ccatgacttt catgatgatg aatgtagcca atagcatata aaaaatacgt
    48001 gccacctgtt ctacaatctg cgacagcgca taaggcatca tttcttgatt gccttgcaaa
    48061 taccctcgta tcacactcat acaaggaaaa accaatacag cgatactcaa agaacgcatc
    48121 gttggaatca gttcttctcc gccaccagaa gcatgagcta gccaaggaga ggcgatgtac
    48181 atgaacaaag caaacaacag gcctaacccg cccatcatct gtaatgcacg gataaataat
    48241 cgtcgtgaag tgccatattc attcaatgaa ttatagcgtg cagtttgttt tgcaatcgca
    48301 gcaggtattc ctgctgtaga gatcagtaga aacaatgcat atatattgta tcccatattg
    48361 aataatccat tggcagcctt agcattttcg cccatccaag cataccaggg aatgatatag
    48421 acagcgccta gcaatcttga aatgatatta ctggcggtca tccaagcaga gcctcgtgcc
    48481 attttttctt gcggtgttaa ttgatctaat gctggttttc tttgattatc catcggtcag
    48541 attccaactt tctacaaaac attactatca ttttaattgg taaaacagaa actggcaatc
    48601 gattttatat aacttttata agaacaattg tttttttgaa ttcggtttcg tttttttggt
    48661 aaagtaaaga aatatacagc cttttatggc taacatttat aggagatatc aatgacacaa
    48721 gaaataaaaa aactacccgt tatattttta ggtcttttct ttatcacagt tggattgaat
    48781 tggttcttgc tccctcacga tatagcttcc gccggagtgg gcgccatcgg acatttagtt
    48841 gaaacggcct tttctatcca acgctcagtt actgtttgga gcatcaatct tatgatgctg
    48901 cttctagccg ctgtcctatt aggaaaatca gtatttttta agactgtagc gggaagtctg
    48961 ctttttcctg ttgttttaga gattgttcca aaagtggaaa tgatctcctc acatttcttt
    49021 tcactgattt caggaagtct tttgttcagt cttggggttt acacattgta cacagtcggg
    49081 gcctcaaatg gcggtataac gataccgccg attattttcc acaaattttt tcggcttcca
    49141 atgccgcaag gacttttact taccaatagt cttatcgtct ttttgaatta ttatgttttt
    49201 ggattgttgg agacactatt cgttctccta tctattacag tcagttcatt gtttatgaaa
    49261 atactcatcc gcttgtcccc tgtgtcaaga aaatttgaat aaagctggat tttgtcatag
    49321 cggaaacaaa cgatatatta aaaagagtgt gctataataa accaagaaat tgaataaagc
    49381 gagggatcaa tcaatgagct tctctttaga agacatccgt catttactat taaaagaaaa
    49441 tctattaaaa gaatttgttt caacaagagg ctggcatctt gatgtaccag aaaaagctga
    49501 atttcttcag ttaagttatg attcaagaaa agctgatgct tctactttgt ttttctgtaa
    49561 aggaatgaat ttcaaagaag aatatttgga ttcagcaatc gaacagggta ttcaatatta
    49621 tgtatcagaa caaccatacg aaaattcagc agtaggaatc atcgtaacgg atatccgtaa
    49681 agcaatggcg cttcttgcta tggcttttta cgactatccg caaaataaat tgaaagtgat
    49741 cggattcact ggaacaaaag gtaaaacaac tgctgcgtac tttacaaaag caatcttgga
    49801 tcacacaaca aataaaaaaa cagcattgct ttctactatg aatacaacgt tagatggcaa
    49861 aacatatttc aaatcccatt tgacaacgcc tgagtcatta gatttatatc gtatgatgtc
    49921 agaagcagtt gaaaatggta tgactcatct agtgatggaa gtttcttcac aagcttacaa
    49981 aacacaacgc gtatacggct tgactttaga tgtcggaatc ttcttgaata tctcgcctga
    50041 ccatatcagt ccgatcgaac atccgacatt tgatgactat ttctattgca agcgacaatt
    50101 gatcttgaat tcaaaaacag ttgttttaaa tcatgaaagt gactattttg atttacttag
    50161 ggaaacagcc gatctattcc agattccaac gatcacttat ggtcgttcgg aagaaagcaa
    50221 ttatcaagtg atccgttcag ataaaggtac tcacggtttt actttatctt ctcatgaaga
    50281 tcgcttagct atctgcgata ctgcttatga tattttgctg gctggaggat tcaaccaaga
    50341 aaatgcagcc agtgcgatca ttgccgcagc actaacaggt gcctccagtc aagatgcaca
    50401 agacggatta aaagaagctc gtgtaccagg ccgaatggat caattgatcc aatccaatgg
    50461 agcgcatgtc tatgtggact atgcacataa ttatctaagc ttgaaaacat tgctgaaatt
    50521 tgccaaaaat gaacatccag atggccgtgt aattgttgta ttaggcagcc caggaaacaa
    50581 agcaatctcc cgtcgacatg attttggaaa agtgctatca gaaacagctg acatcgcctt
    50641 tttgacggca gatgacccag catttgaaga tccgaaaaaa atcgcggaag aaatcaatga
    50701 agcaattact aatccagatt tgatcgttca ttatgaaatg gatcgtcctg aagcgattcg
    50761 acgcgcttta gcagaaagcg ctccgcaaga ttcagtcgtt attgcgggaa aaggcgtgga
    50821 tccctatcaa aaaatcaatg gtgtagatga accttatgaa ggggattatg caatcgtgaa
    50881 gcggttgatt gaagaataat ggtatttata tactagtggt ttcccatttc taagaaaaaa
    50941 agggactgtg attttttgtc acagttcctt ttttcttaga aatcatttta acttttcact
    51001 agctaattct gctgcctttt ctctttcttc atttaataat ttattatcat agaatttgat
    51061 aaatgggaac cagataatga atgcgatgat tgcacaaatg actgctaaca cagcagcttt
    51121 ccaatcacca ccactaccaa caaatgctcc gatcccgact ggtgaaggcc acggcatctg
    51181 tgcaagcatc ggtttgacga tttccagccg aatggcaaaa taagcgagtg tagcagaagc
    51241 catcggagct aagaaaaacg gaaccgctaa atagggattg tagacgattg gcatcccgaa
    51301 aatgattggt tcattgatat tgaataatcc tggtacaagt gaggcttttc ctaacacttt
    51361 cagctgatca gatttcgcga ggaatgcaat aaagatgatc aatcctaaag tcgcacctga
    51421 tccaccaacg gttacataag aattgttgaa ttctcctgcc aacggataat ttgcgccttg
    51481 tgcgttagct gccatattag ctaatacgat cggggtcaag aaagaagtga tgatattcgc
    51541 tccatggatc cctacgatcc acaatgcatg gatcaagaaa taaatcacca tgacaccaag
    51601 ccatgtattc gtcaactgcg taacaaaccc aaatgggata gcaatcattt tgaagatatc
    51661 cgttcctagt gcaactaata atccattgat gatcatcacc acaaacgcaa tgacaaatgt
    51721 tgggatcaga gcagtgaaag aacgagaaac tcctggcgga acaacatctg gcatttttat
    51781 gacccaattt ctcttgacac acatacaata caattcgacc gcaataatcg acataataat
    51841 agctgtaaag attcctgaag ttcctaaacg ttcgacaaaa gagcccatcc taataccatt
    51901 tactacagtt tctgtctcat tgatagaagc aatcaagctg attttaccat cagtcatgat
    51961 caattcaggg atacacataa agaatgcaaa aacagatagt aatgcccccg tgagcggatt
    52021 aacatttaat ttttgttcat ctcgttcaat tgacgttaat tcataagcaa acacaatggc
    52081 aaagtaaata gataaaatcc ccatcgtcat tgtattgacg atcatgtaca agtcactaac
    52141 tttgaaaaaa gttgcattaa aaaatccttc taaaaatggg aacggtaatg gcaaaatatt
    52201 taaaaccaaa aacatcgagc ctacaatcgt gaaaggaata gaagccatcc ccgctgccat
    52261 gacagcccga acgattttaa gttgcgcaat tttccccata ggtcccatca ggtatttctg
    52321 caaaaaatca aacattagtt attctccttt cctaaatata acgctttttc atattgttta
    52381 atacggatat actgttggtc ttggttgagt gaaattttct ttaaacgata ctgtataaat
    52441 gcactggcaa aaataccgct tacaacaaga atgaaaacaa ataactgtcc tccattgtta
    52501 tttgccataa aaggatacaa gaatgtaaat cctgaggtaa acaacactgg aatcactaat
    52561 aaattaaaga cactctggaa caaaaaatac cactttgtcc atggaacgtt cgtttggtgt
    52621 tttcgataaa gctttacttg ttctcctact gcaggcaaaa tagctaaaat cagaatcatc
    52681 ggtaaactac ttcctaaact tttagctgat agaagcagaa tcatccattg catgttcatg
    52741 aaaaagaaaa aggcagtcag gtaacgtacg attagataac gattgaaata catgtttttc
    52801 aaactaagtt gctttttttc taattcgatt ttccttttta ctgtatcctg cacaatgatc
    52861 cttcctttct atttattttt ttgatacaaa taattcattt cctgtgcaac ttccaataat
    52921 gtcatcgtcg tcatcagatg atcttgtgca tggaccatga taatttccat ttctattttt
    52981 gtcccgctgg catattcttt cagaagttga gtttgtgact gatgcgcatg aagaatctct
    53041 tcatttgctt gtcgcaactt ctcttctact tcttcaaaca tctctttacg catcgagcga
    53101 aatgcttcat gtatcagtgt ccgtgcattt ccgctatgga aaatgatatc aaaagaagtc
    53161 acttgtagtg tttcactgtt tattttttca gccatctgtt ttcctcctta ttcgatcagt
    53221 ttgataaatt tactgctgaa attctcaaaa ataggttcag ctaagatttc ctgctgtact
    53281 tttagctggt caactaacct aacgattgct ttagtcacga ccgtaattcc ttcattttcg
    53341 acataagaag gcgaaactaa aaaaacaaaa tgaatttctt gatattgatc ccactgcatc
    53401 ccagaaggaa tcaatgcaac ggctaccttt gtttcgattc caactggaac agcgggatgt
    53461 gggactgcca ctgtatcact gaatatgatt tgtcccatat tttcacgttg ctggatctgc
    53521 tttcgcattt ctcttatata tccttcttct tcatttatgc tcagcttttg cagcaaatca
    53581 tgaagaattt cttccttttt cggttcgtac gtataagtct tgaaaaattt ttcagacaac
    53641 tgttcggtgt aaatctgctt tttttgctgt agagaaaatg ctggtatcgg tctatctgag
    53701 gaatgatagg gtatagattc tccaactacc tttcgtattt tacgaacatc atcttcattc
    53761 aaaaaaatac tgacatgtaa aactggaatt ttgaaaaaca ttgtcgaaag atcaatagaa
    53821 gaaataatca ggtcgattcc ttttaaagtt gtttcattga tctcataata gccttttaca
    53881 cttaccactg taatattttt accgaattca ctgactacgc gattctttaa tagttgggca
    53941 ctgccgtaac ccgttgcaca gataatcaat gcatgtagtt tatgcgcagc tctttctttt
    54001 tccaatgccg ccatgagatg caaagccaaa taggcccatt catcttcatt gatggtatag
    54061 tttttcaaag ccggcatgtt gctgaaatgc ctttttactg cgtcaaagac tttgggattt
    54121 tctttcttta tctcctcagt caatgggttc tcaatgcgaa tacctcggct caatcgaatc
    54181 atcatcggtg acaaatgatc gagtagtcca ttgaaaagct ggagatcctc tactaatgaa
    54241 aaatgaaatt cctgagacaa tcttttcaga actttcgcta attcctttga tagttcctga
    54301 tcattttgat tttctttgtg attcgactta gccatgagat gtaatgtcaa ataagcaatt
    54361 tcttcttcgg gaaacgatac acctgcgatt acctcaatac gttgaacgat ccgctgcgcc
    54421 acttgatact ctactcgctt agaaacttct tgttcgatgc ctaattcctt gatttcaaac
    54481 ccttctcgga gccgtttgat ccccaaagcc aagtgtaaag tcagattctg tatgataaaa
    54541 tccgaaactt ttaacttagc ttctcttgtt tcatcgagaa tgataatgac tagctcttca
    54601 aaactgatgt ctgggaaaaa acggctttgc cctaaatatt ctttcaatga atttccataa
    54661 tggtttccaa aaaaagtatc catgataaaa tgccgtcgat ttctttcttc cccttcgatc
    54721 catgtccctt gaccatgctt agaaacgatt tttagtgaat atggaatcaa tcgctccttg
    54781 atttcttgca tgtcctttgt caaactggaa cgactgatat aaagctcttc tgccaaatca
    54841 tccataaaaa gaatggcatc ttccaaaagc aattggttca atatatactt ttgtcgatct
    54901 tcggactcat aaaatccttg cggttctcta gcatatccag gtactatttc ttgccgactc
    54961 aaaaacaagt caaatgtcag tctttgtaaa atatgcagtt ggtagccata acctggttta
    55021 gcaatgatct tacctccgtt tttttctact aactctttga tccgctgcaa gtaattacgg
    55081 attgtccgat cagataataa caattcagaa gctaaacgtt gactggtgac atactccttc
    55141 ttgtgatcaa tcaaatatct caacagcaat ttttccttct gtttcattat catccactcc
    55201 tattccatca tatgttctct tcgatcacct ctgctaactt ctggatgcct gtagggattg
    55261 ggacatacgc ttggaaaggg atactaacaa caggctttcc aacagattct cctaattttt
    55321 tgaatttatc caaaaacatc gtcgtttgcg ggctgatcag aaataaatca aaatcactat
    55381 tcttaatcat attatcgcct tctgtagctg aaactgcatc tacgagtacc tcttctcttt
    55441 tttgcttaaa gaaatccgtt gtctttgagg ccatcatcga ggatgacatt cctgccgcac
    55501 aaataatcaa tgcttttttc ataaatcaat cactcctttt atttttataa accaagcata
    55561 tcttgtaagc gttttctatt caaaatatat atttccgtag cattgcggaa aaaatgtgta
    55621 tcatatcttg aataataatt tctggcaccg tgatatacta gtgatagaat tttttcagga
    55681 ggggatttag tgagtatcac agtgaatatt ttgtatacaa gtacaaatgg acaagccaga
    55741 aaatttgcag aagaaatggt cgaaagaaac attgtcaaag cgattcgtgc agaagaagga
    55801 aacgagaaat atgactatta ctttccacta gaagatccag aatctctttt actgatcgac
    55861 cgttggaaag atgaagaagc aatcgaaaag catcacaaat ccgaaatgat ggctcaaata
    55921 aacgaactcc gtaaaaagta taaattaaaa atgaaagtcg aacgtttcac tgatttaccg
    55981 taaaaagata cacatggaat gatagcaatt tatcatccat gtgtatcttc actttttcct
    56041 tattttttat tcgatctcat ctaatgattc aaaccgtgtt tttctcttat ttttcggata
    56101 agtatttcag tcaccccaat atacatgatt cctaaacata ccccaaggat attctcaaaa
    56161 atgcggatcg ttactgctcc tggaaccccg aataaactgg cagtgattgc caaagcacca
    56221 aaagaattaa aaactgtttt atatctatag gtagaacaaa cacctaaagc tagaccacct
    56281 aatataccga cccagttaaa aggaataaat tggctgatac caataaataa aacacatcca
    56341 atcaatgagc caatgattcg gtctactgct cgttctttga aaccaatcga catcaatcca
    56401 tagctagata caatagaaga aaatgcaaac cctgcccaca tcaatcgctg aaaagggaca
    56461 tactctcctg caacgatcaa aagactaatg ccaaatgcat agatgagcat ccaaattttt
    56521 tcctgcgaat acatgccttt caaaaaaatc tctttaaaca agcttttgtc tttgttcttt
    56581 tctcgatgtt ttctgtaaag gagaactgaa aaccaacaaa aaaacaaaaa taataagcta
    56641 cttgtttgtg taaagaaatt cttgttcaac gaatctttag gtaacgaata aacaataaag
    56701 agatatgaaa agccgtacaa agaagcattc cccattttgg gatcactagc ggttgccatt
    56761 aatatgctgc ttagtaaaat aaaatgaatc aacatgccca taactgacca tttgatcagc
    56821 tggacatacg gtgctactaa tagtgagaac atgacgattg ctaaacctat gatcgaatgg
    56881 gaaatcttat aaccaaagtc aacaaaacga atactcatca acatacagaa taaaaccaca
    56941 gcgtatggtt tatgcttcga ttcaaataat gttgtaatta taatgataaa acaaatggca
    57001 aacaatacga tgaataatga tcgtaaaaac aatgaacaaa tatacatgca cttttctttt
    57061 ttagaagctg cttctcgtat tttttgtttt aaaataaacg gatctagttg tagagactga
    57121 taaaaatcca cctgttgtcg tcctttcttt ttacttttat tttttacagt catctatgac
    57181 aggttgtaaa tactatggaa catcatatgg cgttgtcatt ttcttgtcaa ctatttttcc
    57241 tattcatgtt tttataaaaa aacatatcgt tttcttgtat gattaaatca ccacaaaata
    57301 aacaactgag agaacgatat gctttatgaa tggttctatc aaaaaaattc tgagatcaat
    57361 agacaaaaat ttgatgatta cagaggtctc ttacgaaacc ttacagaaga aaaaaacatt
    57421 gatcgttgct gcagttctct tccctgctcc atgtgtctgt agaaattgtg gttctgctgt
    57481 ggtagatgga aataggaaat taatggtggt gaaaaacaag aagaaggaaa ccattgtcca
    57541 ctttgaataa tataatcata tgccaatggt tatacgccta aaaaagcagc gctatacctg
    57601 taaaaactgt cgaagccatt ggaacgctca aagttatttt atccgtccaa ggcactcgat
    57661 ttcaaatcat gtcagacata aaatcacttc tttactgact gaaaaagtgt cgttattttt
    57721 tatttcgaaa agttgttagg tatctttgac aaccgttatt cgcacattga aagagttgag
    57781 aagctattta ccaaagtctt ccaaaagaat tctgtcttga gtgttgaggg ttgtgaattt
    57841 cgttctcacg tttccgttga ggataaactg agttttattt ccgcggatgg cgagacagaa
    57901 aaattaatcg agaaaattta cctacacaaa aaattcctcg attaacaaac tatttcctta
    57961 gctgcactaa tcctaaagaa atagaattct tagttacaga catgaacgcc acctactttc
    58021 agctcaccaa acatgttcta ccaaatgcga aattggtgat tgatcgatta cttggttttt
    58081 ccacgccttt caaggaggcg taacctttat tcacgagttg gttgaagctt tccgagacaa
    58141 aagacccgac ttgtttttct ccttattgac aaagagccat taaaactaga gaaaaaatta
    58201 caactgatcg ctgattattt gtagaaagaa aatcaaagta ttacccaata aacttgagtc
    58261 attaggcaaa aaacactgcg aaactcaaga atgattttcg cagtgttttt gtatattttt
    58321 tattaactag tattactaca aaggtttatt tttcacttct caacgcagca caaaattgtc
    58381 tttacttatt tactggttgg gttcaacctt ctctactccg atactaatat ttgtttgtat
    58441 accccttcta aaatcggtag tttccattca attgatgggt actagttgat tttaaaaact
    58501 atgcttattc aattttttat tttagctcat atatttcgtt tctttctaaa ttttatactg
    58561 atgaaaacaa gtagcacacc caatattgac aatataaact ggctaatgat ggtttctcca
    58621 gtttttggaa gatgcttatt tccactgctt gttggattgt ttcctcttat atctgagcta
    58681 tcagcaactt ttctattctc ttttgttaaa aagatcgcca cttcttgttc tttttcgatc
    58741 ttgaaagtta ctggtgtcgc atccaattca taccccgttg gcgcttgagt ttctaccagc
    58801 tgatatgctc ctggtgctaa gccatctatc gccagttttc catctgctcc tgtggttaga
    58861 cctgactgca gaacggttcc attggcatct tgtaactcaa aaacagctcc ttgcaggact
    58921 tctccgcttt ggtcatcgat ctttgtcaac acgacaccgc ctggtgtaag tcgattttct
    58981 ttcgtcaatt ctaccaccgc tgtctgactt ctttcgatct caaactcgat tggtgtcgca
    59041 tccaattcat accccgttgg cgcttgggtt tctaccagct gatacactcc tggtgctaag
    59101 ccgtcaatcg ccagttttcc atctgctcct gtggttagac ctgactgcag aacggttcca
    59161 ttggcatctt gtaactcaaa aacagctcct tgcaggactt ccccgctttg gtcatcgatc
    59221 tttgtcaaca cgacaccgcc tggtgtaagt cggtttgctt tcgtcaattc taccaccgct
    59281 gtctgacttc tttcgatctc aaactcgatc ggtgtcgcat ctaattcata cccc
//
LOCUS       DAIGSZ010000009        57457 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.009, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000009 DAIGSZ010000000
VERSION     DAIGSZ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.009"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..788
                     /locus_tag="NOB31_000560"
     CDS             <1..788
                     /locus_tag="NOB31_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0972802.1"
                     /translation="ELKNLNIGNNIKNIRKSKNMTQNDLAIKANISRSYLADVEGNRY
                     NPSIETLDSIARALDVPIVALINDSSTDNIVEPYESLTAENILLKQENEELKYEVESL
                     RKRLYEIQQVVNQGAEKMIPNLKDVSKRIKYIRKKLGMTMEQFGSHLSNSPKSTIATW
                     ESGRNIPSQKKLQLIAIVGETTTDWIKWGTLEEYITSYLIGIGYELYIKDFPEIPHKV
                     FKDIQEKYSDTFSLDKDYELLDSIIKNIFTKYYSKEFEVTQIP"
     gene            802..1584
                     /locus_tag="NOB31_000561"
     CDS             802..1584
                     /locus_tag="NOB31_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0972803.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDPKKVGRKIRSIRK
                     KLGLTMQEFGYEVSNSPRSTVSTWEHGGNLPNKAKLKKIADIANCSVEDLLFDEGFIS
                     EKSQVKLINELKEENSKLKEKIKYYECLFDGIESLLNSRKNS"
     gene            1625..2236
                     /locus_tag="NOB31_000562"
     CDS             1625..2236
                     /locus_tag="NOB31_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0972804.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
     gene            2680..2988
                     /locus_tag="NOB31_000563"
     CDS             2680..2988
                     /locus_tag="NOB31_000563"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972805.1"
                     /translation="MKLEIKEVVCDWGIYVDGETYPFMIFNSKANAQEIMRIMELDNK
                     HERFDSVKKMENECEAVEYQKTCANNKYILGAMGLGKSASIKQVYEESQENCVYENSN
                     "
     gene            3484..4047
                     /locus_tag="NOB31_000564"
     CDS             3484..4047
                     /locus_tag="NOB31_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972806.1"
                     /translation="MTAIYKALKNSNVSEYVKSRVLNNNLDYILENGVADLISKLSDP
                     IDIDHLVVWQDGTLEVSIYGEFYSRNKVTTFKNSISGREDLKGINKNSKFYRTNKELL
                     EKISKRVFELVNPFSKKRSKELFGIFYDGFSAKSNVEKFFYFNDSAYIAVKDSKRIPE
                     ATLEYLEPIKLSVFYSLYEKEIADEAV"
     gene            4034..4918
                     /locus_tag="NOB31_000565"
     CDS             4034..4918
                     /locus_tag="NOB31_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraA"
                     /protein_id="HCI0972807.1"
                     /translation="MKRFKGSKMSKKIGKESLSLGLKKEIVKFKSMYREPEFRLIFQL
                     DIVRGLKISFSCLGYLVWLFIARVGWSNAYSFYKLFAGTDRLKESLEVKEALNILGSL
                     AFSLFIFALFILQVGKIMMSTNDNYINYLKPFQKGIKIICRQGTVLFLLSLYEHEIHF
                     QNYYNTTTKLGAFLLLYLVSNIAEKMLFKHIVKQVFSDIQKESYCLKTPYGNLKNVEL
                     FLFKMDSKWDKYIYRSKEVFLTGSYNKTLQESLYDTGAIFNNEPMVLKDFFGDYELVW
                     NPKQLSEQGAENEFAEVH"
     gene            5417..5671
                     /locus_tag="NOB31_000566"
     CDS             5417..5671
                     /locus_tag="NOB31_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972808.1"
                     /translation="MYNVGDQIDEIVKIGNVKLVKSKYYISETEIIFNTESGCILIWK
                     LPFPKDETTLKKINTLKIRYCIHEIIDKNTYVINQVKVMG"
     gene            6068..7669
                     /locus_tag="NOB31_000567"
     CDS             6068..7669
                     /locus_tag="NOB31_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HCI0972809.1"
                     /translation="MLNSCEYADVLAKILKNGIKQFNSKNLVAFKKNSNKIGAIAGFT
                     SKTNMIKTKGLIYRSIDRVLEDSDVLTHWTPNVYSWLGGGENKTIFGHKEANLIQINT
                     FVADIDYPVGEKKTDLNLLVLYLLEEGLLPTLIVDTPKGYHCYFLIQNYNQETDSFDK
                     ASYISNSNDFKSLRVAKRISENIRKSIQNRLPQVDMGCNHFGIFRFPTKKNIVHYEPN
                     FVDTFEGYLKWSKDFEEKEYALKRSNLSLLAPNSTGKKGSKRQIDTKWYDFLIHTDIA
                     EGDRNKTIFTLALACKSSGLSIGECMDQLDQLQFNNDLSYSEVERTIRSAYRGDYKGA
                     KSSYVNEIIENYATPTEFEKYSINVNRQAVKRKGNRVDPSNWVKFAKPREERKYSHFE
                     ESKADLLAYLERKQRSLKKNELFLSVSMGTISEETQIPVSTLKVILKELRTANTVILR
                     TSRGRYGSTKIATSKFVEAKILNTVIQNKKDKQVFVLELLGTANSHVETILRRYEDKT
                     VPFHANILKEREKSKHAPIRGANTG"
     gene            7903..8202
                     /locus_tag="NOB31_000568"
     CDS             7903..8202
                     /locus_tag="NOB31_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HCI0972810.1"
                     /translation="MVIKKYVYSHPINVFIIGKLGLSVEVFCELYGFKQGTLSSWITR
                     EREVADLPISFLYALSLASGGNMNEVYDCLCEYEKEYKEYLKISAPKRNKKYIED"
     gene            8338..8697
                     /locus_tag="NOB31_000569"
     CDS             8338..8697
                     /locus_tag="NOB31_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HCI0972811.1"
                     /translation="MNIDGIYNESDFKKGDIAVIRSEYDFPSEIGIHTVEGETVCRYW
                     GRKGNLILLLDTDSGEKLKFCFWHNTNYCCEPIPKRLIDVNKESVRYLADGSRIRLTY
                     QKSENSSITRVRDIVLI"
     gene            8714..8932
                     /locus_tag="NOB31_000570"
     CDS             8714..8932
                     /locus_tag="NOB31_000570"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972812.1"
                     /translation="MELIPYVYQHLYKAKSMKDGNEVVGSLICCPPFSYIATIESMKK
                     MCVDELNDGEVKNLKLTRVLERSIEKFK"
     gene            8947..11310
                     /locus_tag="NOB31_000571"
     CDS             8947..11310
                     /locus_tag="NOB31_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /protein_id="HCI0972813.1"
                     /translation="MATVILAEKPDQAEKFAFALADKKIPKSGGKFEFQSEVFGDTIV
                     TWGIGHLVGLSMPEKYEWLPNKEKWDLANLPFLPKMDELKYEVSKGKSQQFTVVKSCL
                     ENADQIIIATDPDREGENIAYNIFKLCKQSIFKKPMKRLWINSLVKSEIIKGFKNLRN
                     AEETISFFEEANARQIADYLVGMNYTELYTLKLQQKGLSGVVSLGRVQTPVNTLVVEN
                     DLSIKNFKSEKYKVIECHTVDREPKVIFKNSREYFKLEKFEEDTKKFGLDSASTGIIK
                     KIEVSKKQTEPQKLFSLGGIQEYANKKWKYSAKKTDKIIQSLYDRGYLSYPRTDSELI
                     TTNEFEYLKANLDVYKSVLGISIDTPCLEPKKRFVDNDKVLEHYALIPTMDIPDIANL
                     TLDEKNIYEIVTRRACLMFAEPYKYENTKVTLDVNGLEFTTSGNVPISLGWKQVDTNL
                     DESDDKEETLPKFHEQETINIDIRFIDKLTKEPKRLTEGKLLGKTGIMAKLGLGTPAT
                     RSNIVDTLLNREYIKIENTNVYPTPKGYLLWDLTKNKDLLIGKPENTAIWEESLGKIA
                     QGSYTQEAFLRNIYNYINKTVSDLKKVEFTSDYLEKTVNQNKFDIGSYQVEEKKKVYS
                     ILNITSGEQFVIFKNISGKAINKKVLQELLLNNRTDKVLSGFKSKEGKAFNARLLFDP
                     NVMKVVMEFEKNSPKGDKKSKHDTVNGYEIVEKAKVFEIKELATGESFIFYKNNSGKT
                     LSSKTVKELLENGKTKEKVTGFISKDNKKYSAYLVFDNKNKVIKKEF"
     gene            11628..12227
                     /locus_tag="NOB31_000572"
     CDS             11628..12227
                     /locus_tag="NOB31_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III toxin-antitoxin system ToxN/AbiQ family
                     toxin"
                     /protein_id="HCI0972814.1"
                     /translation="MNLKNTNSNKSTLYVISDDYINKLKKVDYRVQNNYREQRLYFKS
                     NLKISNKNEEINYYVPLASAKENQRSLTNKSVFKIYGDREEKDFLGVLHINNMIPVPK
                     DCAKVWTPNSPNVDEKYKMLVIKQAKYLKLHESEINESCELLYNSKLGKLDPSYFKKN
                     RKEVITYQKIMTNVESLEAVSIAESQRNIHVQTQSIDVE"
     gene            12339..12563
                     /locus_tag="NOB31_000573"
     CDS             12339..12563
                     /locus_tag="NOB31_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972815.1"
                     /translation="MISMARPRKYNTEEERKEAMKKARKKWVEKNQETIAYIRAKSFA
                     KKFIEMSEDEDIELLEKWLEDRKNNGQNDE"
     gene            12945..13151
                     /locus_tag="NOB31_000574"
     CDS             12945..13151
                     /locus_tag="NOB31_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972816.1"
                     /translation="MIENRVLGFVECKDNLDDTLEVLESIIFNTKVLDLKAINGDMTT
                     HIILDEISAKEIGETLIAWANKEL"
     gene            13231..14085
                     /locus_tag="NOB31_000575"
     CDS             13231..14085
                     /locus_tag="NOB31_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI0972817.1"
                     /translation="MMKSNFLGYVIAINMFKGGVGKSTLTQLMADILSARGFKVLVID
                     VDPQGTVTKKFQRQYDLKVVGKMTLFEAVINMSFLDCISPVKENLDIVLGSEQMSRFT
                     KVLRDMWRSTGFTDEGEEVFWNLFNYMIGNDNLRDQYDFILFDTIPTVSEFTDNVYVA
                     SDFLVIPTQTEQDSIDNLHSTVTNYQTAVKEVNGDLEILGIVPYLVDTKLKTGLELLS
                     ELQEEYGDLVYSHIVSERGVIKRWGREGLNKSIPHSKTAYSMYVDIVEETLVRLEKAT
                     GENILERV"
     gene            14098..14535
                     /locus_tag="NOB31_000576"
     CDS             14098..14535
                     /locus_tag="NOB31_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972818.1"
                     /translation="MMSKTKKVTSAGSNGSGNPFGIKSGSGGFNIGQQMLKGKAGIKS
                     TGDKRKSVRVPVELYDEVVKDLSYGAKYSLMTEILALFLKEFETHGNSIVTDFGKLKT
                     RPVKISEEAFKVLKVIKFETDQSNTNIIASALTWYLDKRKGKA"
     gene            14553..14852
                     /locus_tag="NOB31_000577"
     CDS             14553..14852
                     /locus_tag="NOB31_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972819.1"
                     /translation="MDHKSNYSYKENYIWKYVVAVFLLVGGIIALVKWAIIPNALVFI
                     NWFVPNFWSFFGYILIIWFMFKVLSFFWSPVYSLLGKWSYLILIATAIYIIMQIN"
     gene            14855..15298
                     /locus_tag="NOB31_000578"
     CDS             14855..15298
                     /locus_tag="NOB31_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI0972820.1"
                     /translation="MQILEDIKIYWKRIIGYTLVLLVVNLFLSMIALVFVNQRKDNVT
                     ELVTFISFFISGIFAPFFEETLMRGIIQNQLELKTNLSTRSIYIIVAILFSLSHLNLY
                     FIPYFMTSLILSFVYDNSDKRLIVPVTIHCFYNLIVILLSVVFYT"
     gene            15443..15766
                     /locus_tag="NOB31_000579"
     CDS             15443..15766
                     /locus_tag="NOB31_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972821.1"
                     /translation="MARSRIAKIEQTKKDKKISKNKTKFFKAEDVKRIAWSVKTFDED
                     RYVKVSMNGLFVQLGNFSNFKTIDELYPEIRNIVDSKGLIVAKRKSRNSGLAYCKNKG
                     IMIPA"
     gene            16184..19813
                     /locus_tag="NOB31_000580"
     CDS             16184..19813
                     /locus_tag="NOB31_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972822.1"
                     /translation="MKKLKLISIALFSLITMSTARQSIVSAEGTSTKAVVEESGDKKV
                     AIDDKVKNEAEKATVVQGADGLMYVVVDENDPEKLLEAESPLKNQQENTGAVEVGVDE
                     KRQEKADKANEKVKNFDDIDYNDISSLQSALNDPKFPFLSEDELNEKLQKTKNTFESE
                     ALMKKTRGYFSQRILELSNNLNDVPKRAKVSRHALVSNRASQVSETRINPPNGYPWVI
                     YLIRSNGYSYTENYAIRRTIDGKEAFCLQAGVQATNTYTGSTSGYLSNSQREMISSIL
                     SAYKELGGWANNDAGKQRWIATQMLVWENSNEKPKSITVTPNWKNGATKWKNDLVARA
                     NAIRVRTKWDSTSKTVDEGDKATFKVTNTYGDHNLHVKSVSGGGKATISNGTLTVDTT
                     GATGNKITVDMIKGSHPSDAHPTTVWSNGSYQKLVTGSFYISTSVTVNVKRKGTVEVL
                     KVDSETKKPLSGATFRFSYSGKTKDVTTDSNGKAKLTERLKAGTVVKVKEIKAPNGYQ
                     LDSSEFSITVKENQNVTTTRTNKKSTGSVEIEKIGDLDGLGLPNVVFTIYNSDNKVVK
                     DNLKTDSNGKIKVDELQFGKYYAVEKQGVTGYDPDGKKYNFEISQDTPFTKPAKVKVT
                     NIYEVSISEKVSDMNESQVLKNNWSADPNDYLQYDITTGNLKKSGERNVQSFIIEGFY
                     DNKNVDVSKSEVYVGSTNVTNSFDINNDTNNGKVIAKAKTSVLTNNDFYNKSYNLRIT
                     MKIKKSTLENTEKQKNLTIVKNSKVTVGSKISKSASSNDVETVLYSRKVTINHIDEKD
                     KHLLKQDIDYKYDGETYEYKPRTDLFDKDGNNYKSDVIHKGKIDGKDIVLNTPYHIPV
                     LSVNVDRIQIDTARAVKNGYLPTKIELSKKEEYEKELEKIVFKVKITDIDNNKVVYDE
                     NFKYKEFNSHMSLDLPTEYLTKNKKINYSVDILLVDNPDKNKFETETKDLRTIGYTSS
                     EKVLTNKDMTNNQVNYSAVVRTVKERENNNPVKEFNESINYKFTDSTKTKTGYGISVD
                     LEPTYRNEIGKQIDMKVYSYPMNELIDSKIDEIYQSGGKETEVKMDRLKNDGKVESGI
                     STQNLSFQFPHMNIERKTGNIYADSQRNDESIKYELIDGGRKLYVPIWCDLGNYSIAI
                     KSSNFGGNYISLDMNQNIDVYAYMYATIDSETKKDDELLLEPVYPESTLPDGWSKNEI
                     DWLNK"
     gene            19873..20235
                     /locus_tag="NOB31_000581"
     CDS             19873..20235
                     /locus_tag="NOB31_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972823.1"
                     /translation="MRVQSYGNSVFDVKREFQDSRRKTKKLIAYFILSAIVFYIVKFV
                     LELNSIVFTDMVHKMLNGEPINFNFDYMLEKAQSNQIVAFIVSIYYFIEKSIFSLKDF
                     FFEMLTKLTTFYNKISKN"
     gene            20249..20401
                     /locus_tag="NOB31_000582"
     CDS             20249..20401
                     /locus_tag="NOB31_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972824.1"
                     /translation="MLDQNTDRSWWMIGAVIVGAILIGTAKVAFPEVFNIVITFFKNM
                     IPTNLG"
     gene            20469..20891
                     /locus_tag="NOB31_000583"
     CDS             20469..20891
                     /locus_tag="NOB31_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972825.1"
                     /translation="MIYVAFFLDGSDVMLRDMPKMILLMFVGFFLILVIAYYSLNGYT
                     QDSSVKGMQETLRTTAIANRDDSIRVEKGRFALIKSDFEKDFKEKFGKSKNLNNETAD
                     YKFDYLTDGKDGIKAIKVKVESGSKEYQATCILNVAND"
     gene            20903..22318
                     /gene="tadA"
                     /locus_tag="NOB31_000584"
     CDS             20903..22318
                     /gene="tadA"
                     /locus_tag="NOB31_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HCI0972826.1"
                     /translation="MRVVEEKKISPKIEETPKSKINIASIIKKNGIKENSEAIEGNLD
                     FLTKLLEEDSGNYEPPIEDAKLNMIRDDLTRNYSQEVLQALTDDEIRRKLVQVVLKEH
                     GTFFKKDKEVAEYVVRECIGTGIIERIMTNDEITDVGWNGSQLSIETNSNKWLFDGDK
                     LNITQEYIERVISKYAVVNDRAFNSGNPIMDGMFKNVRISATHIDNSPDGSTFSMRVA
                     RPRLALNKENFEDFAPDYILELFEKMMKTKANICISGETGTGKTELQKLLLSFIDNHD
                     RMIMIEDVQETHAKELFPDKDIFSWITTPKKAISDLVKASLRNNPRWIIVSETRGSEA
                     YEMLQAVLSGHYVVTTLHAVNARAIPRRFVNMCASGFKINENAVEEDINRYFDFGVHI
                     KKTVVDGKVIRYLNEIVEFSASEPTTVFKQKFINGKFVIENGSLSEDFKEKMAEKFIT
                     FEFPEDQTNTEESLPEEEEVI"
     gene            22335..23150
                     /locus_tag="NOB31_000585"
     CDS             22335..23150
                     /locus_tag="NOB31_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972827.1"
                     /translation="MTKRKGLMDVSELNAYQVAYGKPLDYRDYLNYVGLPCLFMGGFS
                     FALCYYWWIALICGVIGGVYGFKVIMPKSIKRSYELKSLQERNKFINNMTQILTDDSK
                     TVTRALSIAKQRTKGELREDIQILESRLQGADKFQIAEAFREINNKYYSDVVFTQYFE
                     QLETAIYEGRNNSDTMKQIKSYHNDVKRKTEGFMKIKDGYLQDMKQMMFIVAVFIGAI
                     TFAFGFSTFYEGFARSPIGWVFGSIYFLIMVSFMKSFFKHYFDDEIMSLGVSN"
     gene            23150..23947
                     /locus_tag="NOB31_000586"
     CDS             23150..23947
                     /locus_tag="NOB31_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972828.1"
                     /translation="MKVKALKKKRKSSISPLKITKTEHKSFWIKLLGDVYYQKLREMN
                     NSNIAIIKWQKQRLKKSLIFILVGFLMYLFLGKEWYYLAGGIATSVGFYVWQAKSING
                     IYNQFRFERHLQFSKFTRLLIPYLKQKKDGGNLYGVFAKIVKRLDYDTDKKLLMKLMQ
                     EMTDQPNDIRPFTEYAEQTSGTDMSVLFMSTVYDIRQGSADLDVIEELDRLASEELMA
                     GIDSIIDYKSRRFVFFPTKIAMTSFILVVGFAVGVLFMNLKDINFGQ"
     gene            23965..24327
                     /locus_tag="NOB31_000587"
     CDS             23965..24327
                     /locus_tag="NOB31_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4320 family protein"
                     /protein_id="HCI0972829.1"
                     /translation="MQEQSVMEIIKWFIGLMMIMAMVSIGLFCVQLQDINTFKQQVNY
                     QIERKGGLTTEAVEAIDKYSATNYDRRFTIESDKLNQKVSYGEEIDYTIKATIPIQIL
                     PLPDVTLSFNGNSVSQIR"
     gene            24341..24487
                     /locus_tag="NOB31_000588"
     CDS             24341..24487
                     /locus_tag="NOB31_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972830.1"
                     /translation="MQENNVSRIIYLIGGLIILSLAIAGLVEHWPEIKLLIRNFYDNK
                     MIKM"
     gene            24499..24720
                     /locus_tag="NOB31_000589"
     CDS             24499..24720
                     /locus_tag="NOB31_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972831.1"
                     /translation="MEAIQENRKDNQETSEKNKKKRKKKVDKFTEMTDKIIEKKGLKP
                     KDFDRQAIKEARQKLYDDFVKENISQLLD"
     gene            24739..25014
                     /locus_tag="NOB31_000590"
     CDS             24739..25014
                     /locus_tag="NOB31_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HCI0972832.1"
                     /translation="MKNLVISKFAMLPRMDFFDNVSKFMSNMTSKLQGISLSVIIFCI
                     VVTGLMFLFGEGPSRTAKKWLTYIVIGAIIIFGASTIGQTIKSVGGF"
     gene            25123..26949
                     /locus_tag="NOB31_000591"
     CDS             25123..26949
                     /locus_tag="NOB31_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972833.1"
                     /translation="MNQRFEYNFEDVEPKLLKKGKGLKKKNKYTLKQAEALVGWIQHN
                     WSDKTTITLICSDTEEGTKYAFDGIEITPFSIGGQEKLLFPDIEGQILQAPDSMISDP
                     NKLILDINDQYKHEPDVAEPTKESKSKLNLKLPSVVLPFAKKKNKLMNELIEPEETDI
                     YEEELEEQEEIEELVVSSEETEEVEEIETVSENEEETEEIFDFEDEEEVENVQKGDLS
                     TSSQNGLEAVNDPQVPPYISSQTPNYSPQYQAPNVLQPLRKHETVQLVTLKEYCDLGE
                     EIETSISQMVEKLKPESLFKFIGIPSTGLTNTRIDEYRSNHAMLRLAEVKFENLREHY
                     SRQIISFKAEALDRLRTAVDIAWKKPYDLDVKKNKAEELSKMEAEAEAKLNEFVKRQE
                     NNVNDKIKKFEIEQEIDLKNFIARQEADKAVFIATEKDRTQNLIDSKAESINADLLET
                     KDKFIDEEMYKMKIEMNKNLFDGKQKIKSELATELAKANDNVWENALKFIQEIQDEIE
                     AKTPIWAAEIKEFNSLEEQEHERMKQTKELQLKEESIEIKRLEAEMNLKRMEELDHEN
                     KMLKIKLETALSKNELLAMEQDTKQVVNGSNRVGALNLFSKR"
     gene            26962..27678
                     /locus_tag="NOB31_000592"
     CDS             26962..27678
                     /locus_tag="NOB31_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972834.1"
                     /translation="MSVFNNKVMLGNCYVNHIGFYDGGTYRVLFLRLSVFSYSKDGKG
                     HYENINAQISCPLDRNGETTTTSSHPKALMNKFIFEKLDRNLVEGMKISIHGNIRGTE
                     QVLLNSGWKNFGQLSPLEKEEYQKIPKNELVTRNQTYIYIEEVSMPEKEEFRKSQSKV
                     TKEDVEVAEPNQADEILSDDTDPVNDEGEVIEVFEAEIIEEEEEIKSFDKRMYREKPK
                     GYVNFEDMYYDEYSNEPPIN"
     gene            27691..30549
                     /locus_tag="NOB31_000593"
     CDS             27691..30549
                     /locus_tag="NOB31_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HCI0972835.1"
                     /translation="MKLVQNNEVKEIKNGFVKNSNKILGKLKKVGSFKKNKYHTGKIE
                     GEDLPKSLQDKLNVPLVFIGVFLGSIVFLAITYLLNFLKALLVAIGQSESGLLGVEFD
                     PKFSLAYLKPLGDTKQYFMCAVVAVIGVAYLIYGKLNHESEKNLVYGQKGDSRLSTIK
                     EIKRDYHEIPEKTEVYDGIGGVPISHYQDKYYIDRDTVNTVVLGASRSGKGETFVVPL
                     LDNLSRAKIQSNMVVNDPKGELFSASKETLEKRGYRVLVLNIDDPLESMSFNPLQLVI
                     DSWANKDYHEASKRANTLTSMLFASGMGTDNEFFYKSAKSAVNAIILTIVEHCFNNDC
                     IEKITMYNVAQMLNELGSLFYTDPKTRKEKNALDEYFNTLPQGNQAKIQYGSTSFAGD
                     KAKGSILSTASQGIEMFTSDLFGKLTSKMSIDLKEIGFPKSIQFKVNTNLVGKRISIS
                     FLRKENDVIRLIKKYRVKVKALGLCVLNFNEYLQDGDMLDIRYEEEKSRAWYRIEFPK
                     KQANSHDTSLVTKKFKSGKNYSDLEISTLRLKYTDQPTAVFMVIPDYDPSNHVLASIF
                     ISQLYTELASNCKQTPDKKCFRRVHFLLDEFGNMPAIDNMDGIMTVCLGRNMLFDLVI
                     QSYSQLETRYDKAFKTIKENCQNHILIMSNDEETIEEISKKCGHKTTINRSASSKHLD
                     TDSSVTSSAEQERVITVERASQLIEGEQIILRNLHRQDTKRNKIRPFPIFNTKETNMP
                     YRYQFLAEDFDTQRDINEIDIACEHINLSLQDNQIPYARFIKDLKTRLEYSIINNIPI
                     SEEDYQDYLNLSGSQQTINEEELLKLVNTEVKSQDMEGQVLSEQEMKINIYLKESQKE
                     AIELVKVINGRLADENSADMVIKTINSQILDTPFIQSLINDSIAIHNVQESKDQIMIL
                     EQQLANAYELAVFKTKNSILNNKIIKLKNAMTKLAKAI"
     gene            30600..33251
                     /locus_tag="NOB31_000594"
     CDS             30600..33251
                     /locus_tag="NOB31_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972836.1"
                     /translation="MQWLKYKWPIIVSLIIILFMAYPQRVFALPWITDNKEVLKFLTK
                     YQDYLQFTKGGFGSIVVQSLSWGLIRGAYFVCKSAENLVPQSLSLFSFVESSSLGAVY
                     QSVLNTVVVGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALILLMPTLIGSTEK
                     LSGIMFAKTLYNDATSINNQDGGVAWSLIEDGVTDLVYINKNDAYDRLGKDGVQKNAL
                     KEKNFFSYDFSEVITVDTAKDLEDDNKKAEYLQSRLTPDGEGNMQAVKIDDGWMSMFS
                     DSFKGGYYRFTKNTFALTLGLLSLAVAYVFSIFIIVTAILELAFKRVLGVLVFATDIE
                     TGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFVSYLGTGGGSSVNPFIKAVAYVCAVF
                     VLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGNGNGSDS
                     GEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMR
                     DMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDRKDGAKV
                     ENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKSAEELIN
                     QKRQEAKYTPEAMNREEMLRKRVEGRTGTNTDEKEALTKERIQEAKNSNTGLEKLVKE
                     NLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIGVRENLQS
                     SSTSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQG
                     FKTVDVRENVQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKP
                     RRRFTYEDNELFRDTLNDPNPLFDNLN"
     gene            33275..33610
                     /locus_tag="NOB31_000595"
     CDS             33275..33610
                     /locus_tag="NOB31_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972837.1"
                     /translation="MPAFYEVKMMYRNPKNIKQEIKLFFFYLVDLGIVAGSVMASVYF
                     AKLMPISPMMKFALYLLAFVVGVWMCVRTPNHPKERNILMLYYLFKMDRNRYHEVEFK
                     RNSRGKIEL"
     gene            33607..34224
                     /locus_tag="NOB31_000596"
     CDS             33607..34224
                     /locus_tag="NOB31_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972838.1"
                     /translation="MIVAESNENKLSGVFDKFLELVIPKDKDMCELLPYKKILKDGTL
                     VTNDNKYQAFFKVKTTDLTSISEDGFMRMVNKLTYLNRVYLEPYKIYSLTYPTETVNQ
                     AIYWKHRIQEAKRSLLSNNDPNLETYLKWNLKLAYDNYERVDLVSTLPELMFVICVYG
                     KTQKEVKNHADVMKQAGGRELDLQRITEGDLINVITKLMNPNTSL"
     gene            34241..34708
                     /locus_tag="NOB31_000597"
     CDS             34241..34708
                     /locus_tag="NOB31_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972839.1"
                     /translation="MLKHCRKGFCKVIKGKNAADLIFEWKESNLINVRGKNGSGKTER
                     VMASIDNSRPRSRALVITDEKNHYKGIRTIEKKYLTNNDLKVVDDILNIYPDFNLVVF
                     DETIPVTEIKGFYQSFSNLANKYEEVLFVWITEEDSNSKSAFFSEKNAFLHSI"
     gene            34724..36301
                     /locus_tag="NOB31_000598"
                     /pseudo
     CDS             34724..36301
                     /locus_tag="NOB31_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tra protein"
     gene            37174..37542
                     /locus_tag="NOB31_000599"
                     /pseudo
     CDS             37174..37542
                     /locus_tag="NOB31_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            37676..38050
                     /locus_tag="NOB31_000600"
                     /pseudo
     CDS             37676..38050
                     /locus_tag="NOB31_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tra protein"
     gene            38072..39208
                     /locus_tag="NOB31_000601"
     CDS             38072..39208
                     /locus_tag="NOB31_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HCI0972840.1"
                     /translation="MEQNKNNNVASTLARQGMKQVSKKIGLALKIKIGVVIGLITLVG
                     LLVIGSLATLQGTQTATNTGGAEVIGGNKPLSPEVQKWQKTVEKYAEKYGIKELVPYA
                     LAIMQCESGGKLPDLMQSSESAGLPVNTLQYEESIDQGLKHLSNVYNIAKSYGMESNY
                     DGIVQAYNYGIAYMHYLGKNKKTHTIETAEAYSKNVVAPSLGNTTGQTYSYVNEVSIK
                     YGKTYLYLNGGNFYYAELVKQYIGGGSGNPANPSEFWGKMKTEMEKYQGWPYVWGGKN
                     PTTGFDCSGLTAYLYQFSAGITIDSYTVTQYEATEAVSIKEAKAGDLIFFRGTYGAPD
                     FISHVGIYVNETTMYDSNSSGIGYHNWQDSYWQSHSPEIRRVKK"
     gene            39223..39873
                     /locus_tag="NOB31_000602"
     CDS             39223..39873
                     /locus_tag="NOB31_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HCI0972841.1"
                     /translation="MIKRKNDNKWKYICGVLIIILVLGGLLSQLHTSNIQAKNKKLDQ
                     EVTQLEEQNSKLSKNISDLNANVEANLTNDDGSELNKQIAEVAKKFVELYPVYDIEKV
                     EEKKADLEKIATPSVADSIVPDDMITTSKKTLESKSTTQKGEAYSSDPTFKSKYKDSK
                     LYTNYVNANTINYFAEVNYKTESSSGDTENTVYMLFEVTNKDGQVLVDNYEIKYLK"
     gene            39887..40783
                     /locus_tag="NOB31_000603"
     CDS             39887..40783
                     /locus_tag="NOB31_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972842.1"
                     /translation="MNKKYSIHNKKEPNKKNKAQIDKVYKKTKGVKLYLGAILGFLAI
                     GMIIVFSPYVMGKSYDFETVKMSSAQNVTSSLNMYVADMEINREAGLFKLVLRYQDDT
                     GTKSLSNIKSDYKLNFITNKNNEDVKTKVVKLSDEYTVIYYKNLPKDFGVISVTVNPR
                     YIYPELEPSNDLKEKEIKFYAVDKDIKSNAKLEVESTSDLQKDNFKYQIKAIENSIKD
                     EKKSIEKMNLANKVVQKDIDKANQNLEFQTLDEQTDTKNEISSMQTTIENNKSSIEES
                     ENKIKQFEEKIKQLEKSASRFE"
     gene            40819..41049
                     /locus_tag="NOB31_000604"
     CDS             40819..41049
                     /locus_tag="NOB31_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972843.1"
                     /translation="MCNSIVTIQEKAEEELMRIEAEYKEKRKAIKRKKNAELKKYKEE
                     QALKLGMMLCKYYDCYDINEVLKKANLNQFCE"
     gene            41400..41696
                     /locus_tag="NOB31_000605"
     CDS             41400..41696
                     /locus_tag="NOB31_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972844.1"
                     /translation="MDVSIRGIDPQYVKEIDKKVNKIQERTGKKFSRNDYFLAIIRQD
                     SEIDLIDYKKSEFDLVVEKLLLSNEQMVESISELTSVYERLFNFLISERSDLNK"
     gene            41693..42160
                     /locus_tag="NOB31_000606"
     CDS             41693..42160
                     /locus_tag="NOB31_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972845.1"
                     /translation="MNYPYFKVSATEDVKEKFNKCFEVNKSVFQTKSNMFRYVVSNLP
                     MLTKANQNFRDPEKEELAKNLEEAKLKISELETIIELQKQQLENFNKKEDSTHKDYSE
                     QLNSIEESVYKLLINSGLASKELEEERAEPEQESSRLGEGTMFSSPSLRFTTD"
     gene            42227..43762
                     /locus_tag="NOB31_000607"
     CDS             42227..43762
                     /locus_tag="NOB31_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972846.1"
                     /translation="MVGDDMTEHIFNRKSASIILKAKFETGKSKKNNHMVELQKFVDY
                     ISRQEAIRQDKLDHDYSEDELNELARIEKALEKIEQETDQPVIKDLREMDKYIDYMTR
                     KKAILENVDNEIVNGAFSNTKRYITKKDISKIKESVIEAKNNGSVMFQDVISFDNDFL
                     VREGYYNPETNELNENVLYEATKSMMGKMQEKEELVDPFWFATIHRNTEHIHIHVTAM
                     ERKNTREIMEYDGVLQARGKRKQSTLDDMIFKFGSKILDRTNEFEKISKLRKEVPLEL
                     KQSVKDSLIQLYVENNSRYDKELVKYLKELKKEIPSTTRGYNELPEETKEKIDEVTNY
                     MTKDNPKRKEYDRMTKEIDELYQTTYGKRYNPQEYYLNRKKDFNARMGNAVVGQIKLL
                     KQSEEKNLKSNELKNLLDGKKLNVKFDREKPEFKTKYAKQSYDDFQKRLEERQLAREK
                     NEVHFKKISEKFKDKKLIRKIDRVINDDLNMYRAKNDYEVAQRMIEQEKMRQAREFEI
                     GMN"
     gene            43784..44113
                     /locus_tag="NOB31_000608"
     CDS             43784..44113
                     /locus_tag="NOB31_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972847.1"
                     /translation="MKNFDIVCSNTKNIYLRELLNSDSETIEDVKKIIVLFEKENMEL
                     ENWGLFEIPISGNYCFYNWKTEDDVAFANYFFDKNYFSPLYIDKHSNEQVASSIKEAI
                     KLERVRK"
     gene            44115..44378
                     /locus_tag="NOB31_000609"
     CDS             44115..44378
                     /locus_tag="NOB31_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972848.1"
                     /translation="MIDFRTVMDKLSNGDFRVLIELYLNVTSTVKEFLYSNPKTALVL
                     VAVLIVFAVISFIKKMIPLLIIGAVLILGLYFPEVLDQIKNIF"
     gene            44553..45419
                     /locus_tag="NOB31_000610"
     CDS             44553..45419
                     /locus_tag="NOB31_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972849.1"
                     /translation="MKKLRVIATIPMIFSFALLLSACGKEEAGAKSNEAHNISFIDSA
                     EQKDSRCWLIVETSSKNKTPIDKNEYVKAVIQTKDGKAKVFKTDMEQLTLEKVSKMSD
                     EEIIEQALNADKQKFNDKKKSDIDSYNATLDSVKTELENEEKQEFQNDQKIADFQDSI
                     PKIQADIEEIDGVQYSEPEWKMVSATIKMDNENKSPSMETVKLSYKYLDSPIWNLNSF
                     GEVSSEGELSYESTSMDLKLSIPVATTKVLDNFYSGYSNDELDQLLLTKVASKDNKVQ
                     LDSKGKNVSIVE"
     gene            45574..47400
                     /locus_tag="NOB31_000611"
     CDS             45574..47400
                     /locus_tag="NOB31_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCI0972850.1"
                     /translation="MAYKKGNWKPKTKEQKQKELDDLIKASNSKIEQYQSNPEDMIEF
                     AKFMSKIHNYSPLNLSLIDEGFEGAIAVASYDGWKKLGFQVKAKEKGIGIYAHAPVTV
                     FIDENGEEKTLKEATSEQKEKIKNGELRSKKIKHFKKGYVFDISQTNATEADLPKIFP
                     NRVWNFNIDGELSVSQLEKGVNHLAESMNISIKDMNESGRGEMGSARGEYIQYVDGRE
                     EIVLNSRNSRTQNLTTSIHELAHKKLHNKNEHGSSYSTPIKEFQAEMTSFIVCHNYGI
                     DTSDFTIPYIANWTKNNEKIDPKNFRQIMQEVRETSIDFISTIDKKVLEEQQTAFNAL
                     KNSFVPNENKEQIQQKSDLEFHNFYDSTINDPDRTIHGSYLEAMVDYYRGKYGENSIE
                     LTHSNYDVTAKIGENYVTYYSDTKQFDVCDVYGVVFENPSENKNDRLLLDRSPENCDY
                     VEKFVVESLKACENHELKNDTLKLSEPLRSVVINEAVYNLSENANNYYNEKCWQEEIE
                     NQTNINDVKELNSCMTAEDFYESHKQEIENTITDFESVSGTNLRDTIDNESYKEVASV
                     VAYKLVATKVKYEMDEGTFKIPENSNLEKPTVKTAERSFEME"
     gene            47408..48481
                     /locus_tag="NOB31_000612"
     CDS             47408..48481
                     /locus_tag="NOB31_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972851.1"
                     /translation="MSNEQNYETGGTYRLFHGSMNKFDEFSLDHKGLNGTANGFGVYL
                     TPNKEMATMYAEQGSNGNNGFVYEVNVELEKPISMNERTITDEELSKVIDKLQESNDI
                     LNDYNDVSYYGEKVVKREVIASLSENENDVDLINDIGNTIGDHEATAKAFYDVGKYTH
                     IIAEEQLRQKDVVIVVLQPDKVKIETIHDLNEERNSLESSEDMTDKFVGHKVSEVPIR
                     EVVIKDFEQELETTNYYDKQAWQERIEYLENMEEPVSRLALDSDINEFYDSHKEEIET
                     KLTNLSEKLEIDKEELLGFPVDTSSTEYKKATSIMAYNGAMREIYNEIENDTFEIPPV
                     SEEMENKILKLTNFENTTKFEME"
     gene            48490..48750
                     /locus_tag="NOB31_000613"
     CDS             48490..48750
                     /locus_tag="NOB31_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972852.1"
                     /translation="MIEQENRNFLETQGEYRQINNSHFVICEDVQIAFKMALKYGKSI
                     RKKIIREKKSKKIGFWELSLRDGLNFIFCTEDYYEKYKCTLS"
     gene            48787..49791
                     /locus_tag="NOB31_000614"
     CDS             48787..49791
                     /locus_tag="NOB31_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HCI0972853.1"
                     /translation="MDLKKAKKVSIVDFCKQNGIGLKQDSREYYRLEDHDSCVISDRK
                     NLFKWNSKDLGGDIFDFIKAYYDCSFKEAKQKLEDSDYEVHSFNTKVKKAPYQYQKEN
                     EVPVSVAKSYLVNERRIDTALVEDFLSKGLIKQDKKGNVLFLWKKDQEIVGCTEQGTR
                     KFFHEGKQKDVTWKKIQENSKEYSGFNVTFGQPDKMYFFESEIDLMSYITQKPEKAEN
                     ATFVSMNGLKVGNVLHGVTEHYNKFKSLPSETVLCVDNDKAGRTFIETEFKEKGIGRE
                     GIGISEVKVDVPLREGFDWNDNLTRGKEAFKRFKLEDVSKIVNFTHKLSLNTPVYEME
                     "
     gene            49816..50172
                     /locus_tag="NOB31_000615"
     CDS             49816..50172
                     /locus_tag="NOB31_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972854.1"
                     /translation="MNDTIAILSDSLIDLDKTSTDYMIIEEQLKNKNPEFDIQEKSLR
                     IELPKFKQKKLITILFEIIERYGLTYYQIWTDKKDGQYTKGVSIEAVREDDQVSIKAV
                     QPLMGYNEELLNCLNV"
     gene            50334..50525
                     /locus_tag="NOB31_000616"
     CDS             50334..50525
                     /locus_tag="NOB31_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972855.1"
                     /translation="MEQTRMFWSDRMQDHLDCIYKTREQLNKLDTVRYYFTYFSENDE
                     QRWDIFHDGNYEEFFYTES"
     gene            50634..50852
                     /locus_tag="NOB31_000617"
     CDS             50634..50852
                     /locus_tag="NOB31_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972856.1"
                     /translation="MVNKKETFKVGMEVQGVVIGSGELIEGEVISLLANVAVVKANGK
                     APVVMKKCSMMCLDGLNNPITQRFENVI"
     gene            50889..51206
                     /locus_tag="NOB31_000618"
     CDS             50889..51206
                     /locus_tag="NOB31_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972857.1"
                     /translation="MKDYASRKFIHLEPMKELVINGNEYNDYKSLFVKEQPKGGIRMK
                     NLPDFRLIEVNNLGIIEDYLAKLDEAVKQSIEKNGEDHVLTVVLKDLKDRLEAEAENF
                     NKD"
     gene            51217..51414
                     /locus_tag="NOB31_000619"
     CDS             51217..51414
                     /locus_tag="NOB31_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972858.1"
                     /translation="MRDMTEAVKELKKMYPDVLNMTVDDFHEALKNAESEEERTFYLV
                     LSSYVTRVDQKKVINQKDFKI"
     gene            51411..52379
                     /locus_tag="NOB31_000620"
     CDS             51411..52379
                     /locus_tag="NOB31_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HCI0972859.1"
                     /translation="MILENDKPYYVVIGGVNGAGKSTIYQIQNSKRKELDTDRINADE
                     ILRRFGGNWNKQSDINKSMREVLREIEGHFKEGKSFHHETTFGGNPYPDKKRLLNAKK
                     LGYESFLIYIGLDSPERAIERVKSRVAKGGHGVPEDLIRKRYEFSLRNLAELEKYFDN
                     VSIYDNSDEFSYIYVKENHTVVANNTQEYAWVPKAIQEKNAETPISKQIMMDISQEEM
                     NPKETLERIYSASDDFISDRFSKEAQVDDFYRNHKNEIKERILSISFSTGVSQDELVG
                     QDKRRNSCKLAYINSVGELLVKTDSELLSMELNRDRNIQKTDFEVE"
     gene            52623..53795
                     /locus_tag="NOB31_000621"
     CDS             52623..53795
                     /locus_tag="NOB31_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972860.1"
                     /translation="MTKKIEVYVDGSQEERDSFFGFFWKNSREYVKALNMVYKQLMFE
                     ELIENSIKELDHEYIKRELSLEERIDNLLSNEVIDQKKLDKTKRELSKLRIAKNKEAR
                     DVLTQAIGLKSQTRIRDIAKKLDFDYSDFIDSAKMKASKDFSNDFVGIVTGQRTPRIY
                     RNKNKYGLLPFRGRDIKIHKADKFYISLPKGFRFKVNLGRKPRKARDSALTLERIMDG
                     QYKLNQSNLIFEGKNLFLNLTISFEKDYHKLDFKEGAELTIMFTDLCSGKCLVNNQSV
                     IDFGDSKYISNFKNKIKAMKSREQSRGVFSKGGHGRKRKLDQDRWEAIKKRESNFVKT
                     YNNQCSAKIIQTAIRNKTQIICISEPDKNYGEWAYYQLKEQIINKGKRYGIEVKSE"
     gene            complement(54421..54798)
                     /locus_tag="NOB31_000622"
     CDS             complement(54421..54798)
                     /locus_tag="NOB31_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HCI0972861.1"
                     /translation="MKKSYPVIFSAEENGYSVVFPDFAGATQGDNFEEAMSNAKEFLD
                     GILAYYIDEDISVPSPTDIHQLNNLGNNKIVSLIQSDPSPFIQKKTVRKNVTVPEWLV
                     ARGEKDKINFSKVLTDALLKIYE"
     gene            complement(54844..55032)
                     /locus_tag="NOB31_000623"
     CDS             complement(54844..55032)
                     /locus_tag="NOB31_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HCI0972862.1"
                     /translation="MPLTGKKMLKLAKKNGWKVVRITGSHHIVAKEGFPPVPIPVHSN
                     QDLKKGTEQKLLKDLGLK"
     gene            55203..55745
                     /locus_tag="NOB31_000624"
     CDS             55203..55745
                     /locus_tag="NOB31_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0972863.1"
                     /translation="MKFGGHFLNKKQDQEYYIEKLEKENLELKERIRYYETKFCKRGD
                     CMKPNPVETGKRIKSIRSNFGMTMEQFAILTDSSNTSAVNNWERGYNLPNKTKLKKIA
                     ILGNTTTDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKDIQERYSDTFSLNK
                     DYELLDSIIKNIFTKYYSNG"
     gene            55940..56836
                     /locus_tag="NOB31_000625"
     CDS             55940..56836
                     /locus_tag="NOB31_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0972864.1"
                     /translation="MEINLFEAGNRIKQIREKHGYTMADLGKLVDANSPSTINNWEKG
                     NNLPNRKRLEKIALLGGTSVEWIKYGDFSDYVYRLTQNIEEKILKEYGETTLNNYREA
                     LLDELTIEKITYEEDAKILAAAEKINTQNIFQEVKYMYSPDEDYRNIEVKPDLGLTDD
                     NKNIKMIGQRIRKIRKKENITLEEFGKLFSPTADKAVISNWENGKNLPNSERIKKIAE
                     IGGVSELYLMTGVDSSVAESMYFLSEVALDALERLSIEEVNRIIESFAGYLNVISKID
                     DPDKREISLNAICQLSLLDKMG"
     gene            56885..57259
                     /locus_tag="NOB31_000626"
                     /pseudo
     CDS             56885..57259
                     /locus_tag="NOB31_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353455.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            57254..>57457
                     /locus_tag="NOB31_000627"
     CDS             57254..>57457
                     /locus_tag="NOB31_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0972865.1"
                     /translation="MKFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYL"
BASE COUNT        22210 a         7113 c        11029 g        17105 t
ORIGIN      
        1 ttgaactcaa aaaccttaat attggaaaca acatcaaaaa tattagaaaa agtaaaaata
       61 tgacgcaaaa tgatttagca atcaaagcta acatctctcg ctcttatctt gccgatgtag
      121 aaggaaatcg atataaccct agtattgaaa ctttagactc catagcacgg gcattagacg
      181 ttccgatagt agcattaatc aacgattctt ctactgataa tatagtagag ccgtatgaaa
      241 gtttgacagc cgaaaatatc cttcttaaac aagaaaatga ggaattaaaa tatgaggtag
      301 aaagcttacg aaaaagattg tatgaaatcc aacaagtagt aaatcaagga gctgaaaaaa
      361 tgattcccaa tctaaaagac gtaagtaaaa gaatcaaata tatcagaaaa aaattaggta
      421 tgactatgga gcaatttggt tctcatttaa gcaactcacc taaaagtaca attgctactt
      481 gggaaagtgg tagaaatata ccttctcaga aaaagttaca gctgattgct atagtaggag
      541 aaaccaccac tgactggatt aaatggggaa ctttagaaga gtatataact tcatacctta
      601 tcggtatagg atatgagcta tatattaaag actttccaga gatacctcac aaagtcttta
      661 aagacattca agaaaaatat agtgatacgt tttcgttaga taaagactat gaattattgg
      721 attctataat aaaaaatata tttacaaaat attactcaaa agaatttgaa gtaacccaaa
      781 ttccataaga gaggtgattg tatgaagcca aatccttcag aagcaggaaa acgaatcaaa
      841 caattacgcc tttcatgtgg ttttactatg gaagaacttg gaaggaaaat agataattca
      901 ccacgtgcga ccatatccaa ctgggaacgt gggaccaatt taccaaatcc acaaaagctg
      961 aaattattat caactatcac taattcaaca attgactgga ttaaatgggg aactttagaa
     1021 gaatatataa cttcatacct tatcgatata gggtatgagc tatatattaa ggactttcca
     1081 gaaatacctc acaaagtctt taaagacatt caagaaagat atagtaatac gttttcgcta
     1141 aataaagact atgagttatt gaatcctata ataaaaaata tatttacaaa atattactca
     1201 aaagattttg aagattatcg agacatagaa gttaaaccag accctaaaaa ggtagggaga
     1261 aaaattcgtt ctattagaaa aaaattagga cttactatgc aggaatttgg gtacgaggtt
     1321 tctaattctc ctagaagcac tgtgtcaaca tgggaacatg gtggtaactt accgaacaaa
     1381 gccaaactaa aaaaaattgc agacattgcg aattgtagtg tagaagattt gctttttgat
     1441 gaaggcttta tttctgaaaa atcccaagtt aaattgataa atgaactcaa agaagaaaat
     1501 tcaaagctaa aagaaaaaat aaaatactat gaatgtttat ttgatggtat agagagtctg
     1561 ctgaactcac gaaaaaattc ctagtgaatt agctagagaa aatttaatga tggtaggtga
     1621 aaaaatgtta gttggctatg cacgagtcag ttcagatgat caaaatttgg aaagacagct
     1681 tgaagaattt agaaaaattg gtgtcgaaaa agtatttgct gagaaaaaat ctggacgtaa
     1741 cacagtagaa cggccagagt tcaataaaat gttgtcattt gtcagagaag gggatacgct
     1801 tgtttttgag tcgcttgaac gcttaggaag aaattctgat gaaatactag aaacagtatc
     1861 ttttatagat aaaaatggta tgggcttaat ggttttgaat ttaccaattt tagatacaaa
     1921 atttggtgat ccaaacttag aaaaacttgt tagaagctta gtaattaaca ttttttcttg
     1981 gacggctcaa aatgagaggg aggaaattaa gagaaaacaa aaacaaggaa tagcaattgc
     2041 gaagaagaaa ggagtctata aaggaaaacc ctacgaatat tcttctactg caaagaatcc
     2101 acaaaagagg tttatctata atgaaatagt aagaatgctt ggagaaggtg ttccgattaa
     2161 gcgaattgca gaaaaaacag gaacaaatag aaatttagtc tatagaataa agaaaagaat
     2221 aagtgaatct gattgatttt aagttctttg agaaatcaat gttacgagag aaggattcta
     2281 agcctgtttc aaacttttaa ggtgtacaat tatacaaaga agcttctaaa caaaagaatt
     2341 aattttgtgg cagtcaagta acgacagaaa tagaaaagaa agaggctatg cgagagtgaa
     2401 tcaacaagtt aattgggtta atgattttga aaaagaattt cgactgaaat tttttggaaa
     2461 tcctacagca gaaagtacag aagaaaaaaa ttatgactgg tcagaatttt aggttgcata
     2521 ttcgattcaa taagtgttga agataatagt tctcttacgc cacagtatac aacgttagaa
     2581 tatgacgaaa acagattcaa tacatttcct tgcaatacca ttcaagaatc aattgataag
     2641 catgagtgat aattgattat ctacaggaag gtgtttttta tgaaactaga gatcaaagaa
     2701 gttgtctgcg attggggaat ttatgtagac ggagaaacat atccatttat gatttttaat
     2761 agtaaagcaa atgcacaaga gataatgcgt atcatggagt tggataataa gcacgaaaga
     2821 tttgattcag taaaaaaaat ggagaatgaa tgtgaagcag tggaatacca aaaaacatgc
     2881 gccaataata agtatatttt aggtgcaatg ggattaggta aatcagcttc tattaaacag
     2941 gtctacgaag aatcacagga gaattgcgta tatgaaaatt cgaattaaag agtgagaata
     3001 tgtgggagct aatttattta gttttatact taataggaaa atcaactgaa tttgtatata
     3061 acaataaggt aatatttata ttgttcttaa tagtttgtat tatcgtattt gatgtctatg
     3121 atttactaat tcataagaat gaaaatagta atattggtag aattataatc acaaacttaa
     3181 tagtaattac tattgggatt acaacattaa caaataaagc tttaatatca agtatgattt
     3241 taatagtgtt tgattttatt atcatttata gtttgctgtt tttaataaag aaagtaactg
     3301 aatatttaaa tcgttaggca cgaaataaat tttaattgag gttgaattat agcggtaaat
     3361 catacaaaat agaaatgtag tcttgttaag cgtcttgact atctaatttt gaatgaggag
     3421 ggttgtatat agaaaaaggg tagttaaatt cgtagatcaa aaggctacga aggagaataa
     3481 agaatgacag ctatttataa agcactaaaa aattctaacg tatcagagta cgttaagtcg
     3541 agagtattaa ataataattt agattacatt ttagaaaatg gtgttgctga tttaatcagt
     3601 aaattaagtg atcctataga tatagatcat ttggtggtat ggcaagatgg tactttagaa
     3661 gtatcaatat atggagaatt ttatagtaga aataaagtaa ctacattcaa aaatagtatt
     3721 agtggtcgag aagatttaaa aggaatcaat aaaaatagta aattctatag aacaaataaa
     3781 gaattgctag aaaaaatttc aaagcgtgtt tttgaattgg tgaatccatt ttcaaaaaaa
     3841 cgtagtaaag aactttttgg aattttttat gatggtttta gtgcaaaaag taatgtagaa
     3901 aaattttttt attttaatga ttcagcttat attgcggtta aagacagtaa aagaatccct
     3961 gaagcaactt tagaatattt agagccaatt aaattgtctg ttttttattc actttatgag
     4021 aaagaaatcg ctgatgaagc ggtttaaggg gagtaaaatg agtaaaaaaa taggcaaaga
     4081 gtcattatcg ctcggattga aaaaagaaat tgttaaattt aaaagtatgt atagagagcc
     4141 ggaatttaga ctcatttttc aattagatat agtgagaggg ctgaaaatta gttttagttg
     4201 tttaggttat ctggtctggc tattcattgc tagagtagga tggagcaatg cttatagctt
     4261 ttataaactg ttcgccggaa ctgatcgatt aaaagaatca ttagaggtga aagaagcctt
     4321 aaatatttta ggaagtcttg ctttcagcct gtttattttt gctttattta tcttacaagt
     4381 aggaaaaata atgatgtcaa caaatgacaa ttatattaat tatttgaagc cttttcaaaa
     4441 aggaataaaa atcatttgta gacagggcac agttttattt ctacttagcc tgtatgagca
     4501 tgaaattcat tttcaaaatt attataatac gacaactaaa cttggtgcat ttttactcct
     4561 atatttagtt agtaatatag ctgaaaaaat gctgtttaaa catattgtaa agcaagtctt
     4621 ttctgatatt caaaaggaaa gctattgttt aaaaacacct tatggaaatt taaaaaatgt
     4681 tgagctgttt ttatttaaaa tggatagtaa gtgggataaa tatatctata gaagtaaaga
     4741 agtattttta actggtagtt ataacaaaac tcttcaggag agcctgtacg acacaggagc
     4801 aatatttaat aatgaaccta tggttttgaa agatttcttt ggagattatg aactagtttg
     4861 gaatccaaaa cagcttagtg aacagggggc agaaaatgaa tttgctgaag ttcactaaca
     4921 tagtgtacag aaaaacatta tctgaaagaa gaacgccttc aaaagaaagt acaagaacga
     4981 ttgggccgta cagaagacta acgaaagatc gtaaaaaaaa ggaaagacaa tgaaaatgtc
     5041 tttccttttt ttttgactac aagtagcctg aaaatgaaat ttcaaaagac tacaagtagt
     5101 cttttgtggc aaaaataaag agccaacgaa agctaccaac aatcgttgac tcgtaagact
     5161 gttcgtagta agaaaaatct ttggcaatcc acgaagtctt tatttcataa tttatataaa
     5221 tgattataca gtcactttcc tgaatttgca agtaaaaaag ctaagaaata ttgtttaagc
     5281 gtttccttaa aagaatcttt aaataaattt ttttccaatt gaaaacatga ctacaagtag
     5341 actatttctt ttattccaag ttgactacaa gtagtcaagg tgatataata tatatatcaa
     5401 gaaaggagaa acaaaaatgt ataacgtagg agatcaaata gatgagatcg taaaaatagg
     5461 taatgttaaa cttgttaaaa gtaagtacta tatttcagaa actgaaataa tttttaatac
     5521 tgaatcagga tgtattctaa tttggaaact gccttttccc aaagacgaaa caacactgaa
     5581 aaaaataaat actttaaaaa tcagatattg cattcatgaa attattgata aaaatactta
     5641 tgttataaat caagtaaaag tgatggggta aaaatctttt aaaaaaactc ttgttaaaag
     5701 taattctatt agcttataat gttggtatta gttctgaagc caaaggaaca ctaaaaaatt
     5761 ctagtagaaa agttagttac agactctcta ctatgtatga atgtaacgaa aaaaatagcg
     5821 aaaaagataa ttaaataaga ctaccaatct tatttaatgg aacttctgta gtaagaaaag
     5881 cgatttggca atccacgaag tccaccaaga tgagctacca actcatttta atttttgcac
     5941 gtttaaagtt tagcatttaa gtgcttactc taaagacata gtgtaatttt aggactcctt
     6001 attacggaat ctaaagttac cctatgtctt ttttgctatt caaaattgat agcaaggaga
     6061 aagtgcaatg ttgaatagtt gcgagtatgc ggacgtttta gctaaaattc ttaaaaatgg
     6121 aattaaacag tttaatagca aaaatctagt tgcttttaaa aagaatagca ataagattgg
     6181 tgctattgcc ggatttactt ctaaaacaaa catgataaag actaaaggtc ttatatatcg
     6241 ttctattgat cgtgtcttgg aagattcaga tgtattaaca cactggactc ctaacgtgta
     6301 ttcatggctt ggtggcggtg aaaacaaaac aatttttggt cacaaagaag ctaacttaat
     6361 tcagattaat acttttgtag cagatattga ctatccagta ggagaaaaga aaacggattt
     6421 gaatttacta gttctttatc tattggaaga agggttattg cctacactga ttgtagatac
     6481 gccaaaaggt tatcattgct attttctgat tcaaaactat aaccaagaaa ctgattcatt
     6541 tgataaggca agctatattt ctaattcaaa tgattttaaa tctttgagag ttgctaaaag
     6601 aatatcagaa aatatcagaa aatctatcca aaatcgttta ccacaagtcg atatgggctg
     6661 taatcatttt ggtattttta gatttccaac taaaaaaaat attgtacatt atgaacctaa
     6721 tttcgtagat acgtttgaag ggtatttgaa atggtcaaaa gactttgaag aaaaagaata
     6781 tgctttaaag aggtctaact tgtcattatt agctcctaat tctactggca agaaagggtc
     6841 taaacgacaa attgatacta aatggtacga ctttttaatt catacggata ttgctgaagg
     6901 agatagaaat aaaactattt ttaccttagc cctggcatgt aaatcaagtg gcttatctat
     6961 tggcgagtgt atggatcaat tggatcaact tcaattcaat aatgatttgt cctattctga
     7021 agttgagaga acaataagaa gtgcttatcg tggcgattac aaaggtgcta aaagttcata
     7081 tgtcaatgaa attatcgaaa attatgctac acctaccgag tttgaaaaat actcaataaa
     7141 tgtaaataga caagctgtta aacgtaaagg gaatcgtgtc gatccgtcta attgggtgaa
     7201 atttgctaaa cctagagaag aacgaaaata tagtcatttt gaagaaagta aagctgattt
     7261 attagcttac ttagaaagaa aacaaagatc attgaaaaaa aatgagttgt ttttaagtgt
     7321 ctctatggga actatatctg aagaaacaca aattcctgta tctacgttaa aggtgatttt
     7381 aaaagagctt agaacggcga atacagtgat attacgaacg tctcgtggtc ggtatggatc
     7441 gactaaaata gcaacaagca aatttgtgga agctaaaata ttaaatacag ttattcagaa
     7501 taaaaaagat aaacaagtat ttgtcttaga attattagga acagcaaata gccacgtaga
     7561 aacgatttta agacgttatg aagacaaaac agtaccgttc catgcgaaca tactgaaaga
     7621 aagagaaaag agcaaacatg cgccaattag aggagctaat acaggttaga gttctattta
     7681 tttttttgat ttttaaatag ctaaattgcc aattaacata tctagtgttt ctgcccactc
     7741 ctattcctgt tttagcgtat actaatgatt agtagttagt actctctttt atgtatggag
     7801 tgtatagaac tatttttact tgtgtctttt cccttaatcc acgtgtacgg aatacagctt
     7861 ataactgcgt atgcagttat gtttgaagga ggaagatttt ctttggtaat taagaaatat
     7921 gtttactcac acccgatcaa tgtatttatt atcggtaagc taggtttatc tgttgaggtg
     7981 ttttgtgagt tatatggatt taaacaagga actctatcgt cttggattac tagagagcgt
     8041 gaggtagctg atttgcctat ttcttttttg tatgctttgt ctctagcttc aggagggaat
     8101 atgaatgagg tttatgattg cttgtgtgag tatgaaaaag agtataaaga gtatttgaaa
     8161 atttcagccc caaaacggaa taaaaaatat attgaagatt agagaaagaa gaaaagaata
     8221 atttgttttt tttgactaca agtagacaga tagctactct gttttttgat agtttgatat
     8281 tggctgtttt tttgttagaa ttaatatata tcaggtaaat aaaaaagggg gctattaatg
     8341 aatattgatg ggatttataa tgaatcagat tttaagaaag gcgatatagc ggtaatacgt
     8401 tcagagtatg attttccttc agaaatagga atccatacag tagagggaga aactgtatgt
     8461 cgttattggg gcagaaaagg gaatttaata ttattattag atactgattc aggtgaaaaa
     8521 ttaaagtttt gtttttggca taatactaat tattgctgtg aacctattcc aaaaagattg
     8581 attgatgtaa ataaggaaag tgtaagatat ttagctgatg gttcaagaat tagattaacg
     8641 tatcagaagt ctgaaaattc ttcaattact cgtgtaagag atattgtttt aatctagtgg
     8701 gaggtgaagg attatggaat taatacctta tgtgtatcaa catttgtata aggctaaatc
     8761 aatgaaagat ggtaatgaag ttgttggttc gttgatttgt tgtccaccat tttcttatat
     8821 tgctaccatt gaatctatga agaagatgtg tgttgatgaa ttgaatgatg gtgaagttaa
     8881 aaatttaaaa ttaacacgtg tattagagcg ttcaattgaa aaatttaagt gaaggagaga
     8941 gtatttatgg caactgtaat tttagcagaa aaaccagatc aagcagagaa attcgctttt
     9001 gcgttagccg ataagaaaat tccaaaaagt ggagggaagt ttgaatttca aagtgaggta
     9061 tttggagata cgattgtaac ttggggtata ggacatttag ttggattatc aatgccggaa
     9121 aaatatgaat ggctacctaa caaagaaaaa tgggatttag ctaatcttcc ttttttacca
     9181 aaaatggatg agttgaagta tgaagtttca aagggaaaga gtcagcaatt tactgtagtc
     9241 aagtcgtgct tagaaaatgc tgatcaaatt attatagcca ccgatccaga tcgtgaagga
     9301 gagaatattg cttataatat ttttaagctg tgtaagcaat ctatttttaa gaagcctatg
     9361 aagcggttgt ggatcaattc tttggttaaa agtgaaataa taaagggatt taaaaacctt
     9421 agaaatgcag aggaaactat ttccttcttt gaagaagcaa atgcacgaca aattgcagat
     9481 tatttagtgg gaatgaatta tacagaattg tatacattaa aattgcaaca aaaaggctta
     9541 tctggggtgg tatcactagg tagagttcag acacctgtta atacattggt tgttgaaaat
     9601 gatttatcaa ttaaaaattt taagtctgag aagtataaag tgattgaatg tcatactgtt
     9661 gacagagagc caaaagttat attcaaaaat agtcgagaat actttaaatt agaaaaattt
     9721 gaagaagaca ctaaaaaatt cggccttgat tccgccagta ctggaatcat aaaaaaaatt
     9781 gaggttagta aaaagcaaac agaaccacaa aaattgttta gcttgggtgg tattcaagaa
     9841 tacgctaata aaaaatggaa atattctgct aaaaaaacag ataaaattat ccaaagtcta
     9901 tatgatcgtg gatatttatc ttatccaaga accgatagtg aattgataac tacaaatgaa
     9961 tttgagtatt taaaagcgaa tttagacgtg tataagagtg ttttagggat cagtattgat
    10021 acaccttgtt tagagcctaa aaagcggttt gtagataatg acaaagtatt agagcattat
    10081 gcactaatac caacaatgga tattcctgat atagcaaatc tgacattaga tgaaaaaaat
    10141 atttatgaga tcgttactag gcgtgcgtgt ctaatgtttg cagaacctta caagtacgaa
    10201 aatacaaaag ttacattaga tgtaaacggc ttagaattta ccacaagtgg taatgtacct
    10261 atatctttag gttggaagca agtagatact aatttagatg aatctgatga taaagaggaa
    10321 acattaccta aatttcatga acaagagaca ataaatatag atattagatt tattgataaa
    10381 ttaactaagg aacctaaaag gttgactgaa ggtaaattat taggtaaaac cggtattatg
    10441 gcgaaattag ggctaggaac gcccgctaca cgttctaata ttgtagacac tcttctaaat
    10501 agggaatata ttaagataga aaacacgaat gtttatccta ctccaaaggg atatttatta
    10561 tgggatttga caaagaataa agacctattg attggaaaac cagaaaatac agcgatatgg
    10621 gaagaatcac ttgggaaaat tgcgcaaggt agctatacac aggaagcttt tttaagaaat
    10681 atctataact atatcaataa gactgtttca gatttgaaaa aagtagaatt tacttcggat
    10741 tatttagaaa agactgtaaa tcaaaataaa tttgatatag gtagttatca agtggaagaa
    10801 aagaaaaaag tttattctat tttaaatatt actagtggtg aacagttcgt gatatttaaa
    10861 aatatatcag gaaaagcaat caataaaaaa gttcttcaag aactattact aaataatcgt
    10921 acagataaag tcctttccgg ctttaagtca aaagaaggaa aagcttttaa tgcaagatta
    10981 cttttcgatc caaatgtgat gaaagtggta atggagtttg aaaagaacag tccaaaaggc
    11041 gataaaaaga gcaaacacga tacagtaaat ggttatgaaa tagttgaaaa agcaaaagta
    11101 tttgaaataa aagaattagc aacaggtgaa agttttattt tctataaaaa taatagtggg
    11161 aaaactttaa gttcaaaaac agtcaaagaa ttgttagaaa atgggaaaac taaagagaaa
    11221 gtaacgggtt ttataagtaa agacaataaa aaatatagtg cttatcttgt ctttgataat
    11281 aaaaacaaag ttataaagaa agaattttaa ttcttagtgg cggaaatcat ttgtttttcc
    11341 gcttattttt attcaaaagt gcccaaaata taggtatact gaattaagga taaatacaaa
    11401 actagttaga ggacagttga aaaaatacaa acaaattaga ttgctatttt gttaaattgg
    11461 aagtagaata ataccgtttt gatatgtata gtgtgtttta ccaataaaat tacataaacg
    11521 tgaatatatt tttatgaatt aaatgtaaaa tgagagcaat tagttttaaa aaagattata
    11581 ggctgttaat cttagcatat ataatccatt ggaaaggggg agatccaatg aatctaaaga
    11641 atacaaactc aaacaaatct acactatatg taatttcaga tgattatata aataagctga
    11701 aaaaggtgga ctatcgtgtc caaaacaact atcgagaaca acgattatat tttaaatcaa
    11761 acttgaaaat ttctaacaaa aatgaagaaa taaattatta tgtaccattg gcttcagcaa
    11821 aagaaaatca acgttctttg actaataaat cagtgtttaa gatttatggt gatcgagaag
    11881 aaaaggactt tttaggagta cttcatataa ataatatgat tcctgtgcca aaagattgtg
    11941 caaaagtatg gacacctaat agcccaaatg ttgatgagaa gtataagatg ttagtaatca
    12001 aacaggcaaa atatttgaaa ttacatgagt ctgaaataaa tgaatcatgc gaattacttt
    12061 ataattctaa gttaggtaaa cttgatccta gttactttaa gaaaaatcgt aaagaagtaa
    12121 ttacttatca aaaaataatg acgaatgtag aatcattgga agctgttagt atagcagaat
    12181 cccaaagaaa tattcatgta caaactcaaa gtatagatgt agagtaagat aggctaaacc
    12241 tatcttattt tattattcta ttggatatta tgatacattg aattttaatc gaatatgtat
    12301 ttaaatgtta ttatactgta gaagataaaa cttaaaggat gatttctatg gcgagaccga
    12361 gaaaatacaa tacagaagaa gaaagaaaag aagcaatgaa aaaggctagg aaaaaatggg
    12421 ttgaaaaaaa tcaggaaact attgcctata taagagccaa atcatttgct aaaaaattca
    12481 ttgaaatgtc tgaagatgaa gatattgaat tgttggaaaa atggttagaa gatcggaaaa
    12541 ataacggtca aaatgatgaa taataaccat tgactacaag tagtcaatgg tgtagaatgg
    12601 ttttagggat agaaatatcc cttttctaaa agtctaatga ctacaagtag tcgatagagg
    12661 gatcgggaat aaaaacagac gattatggcc taaagaaagg aggaatatga atattttgag
    12721 gaacgattta ttaaatgagc gttgataaat ttcactaaat attttcttaa tatctatgta
    12781 ttgttcaagc gtagaaaaaa atattgaaat tattacaaaa ccgctcataa tggaaaataa
    12841 cgaattatat taatgaatcg ttcacttttg acctttttta ctagattttt ttgtaggact
    12901 tttagagaat ttttttgtta tctgattata aggaggagct aaagttgata gagaatagag
    12961 tactggggtt cgtagagtgt aaagataatt tagacgatac tttagaagtc cttgaaagta
    13021 ttatatttaa caccaaagtt ctggatttga aagcaattaa tggtgatatg acaacacata
    13081 tcatattaga tgaaattagc gcaaaagaga ttggcgaaac tttaatagca tgggctaata
    13141 aagagctgta aaagataatt ttaaaataaa gtggccaatt gactacaagt agtctgtata
    13201 gtataataaa ttatcaaaag tgaggtatac atgatgaaat caaatttttt gggatatgta
    13261 attgcaatca acatgtttaa agggggagtt ggtaagtcaa ctcttactca gctaatggct
    13321 gatattctat cggctagagg ctttaaagtt ttagttattg atgttgatcc acaaggaaca
    13381 gtaactaaaa agtttcaaag acaatatgat ttaaaagttg ttgggaaaat gacattgttt
    13441 gaagcagtaa ttaatatgtc tttcttagac tgcatttctc ctgttaaaga aaacttagat
    13501 attgtgcttg gttcagaaca aatgtcaagg tttaccaaag tattaagaga tatgtggaga
    13561 agtactggtt ttactgatga aggtgaagaa gtcttttgga atttgtttaa ttatatgatc
    13621 ggtaatgata atttaagaga tcaatatgat tttattttgt ttgacactat tcctacagtt
    13681 tcagaattta cagataacgt ttacgtggcg agtgattttt tagtaattcc cacgcaaact
    13741 gagcaagatt ctatagacaa cttgcatagt acggttacta attatcaaac tgctgtaaaa
    13801 gaagtaaacg gagatttaga aattttaggt attgttccat atctagtgga tactaaatta
    13861 aaaacaggat tagaactttt atcagaactt caagaagaat atggagactt agtttattct
    13921 catattgttt cagaacgagg cgtaattaaa cgttggggta gagaaggact aaataaatct
    13981 atcccacatt ctaaaactgc ttatagcatg tatgtagaca ttgtagaaga aacgttagta
    14041 cgtttagaaa aagctacagg agaaaatatt ttagaacgtg tttaggaaag gtgttgcatg
    14101 atgtcgaaaa ctaaaaaagt aactagtgcc ggcagtaatg gttcgggtaa tccgttcgga
    14161 ataaaaagcg gtagtggtgg atttaatata ggacaacaaa tgttaaaagg taaagctggc
    14221 attaagtcta ctggtgataa acggaaatct gttagggtac cagttgaatt atacgatgaa
    14281 gttgttaaag atttatcata cggggctaaa tattcattaa tgacagaaat tttagcttta
    14341 tttttaaaag aatttgaaac acatggaaat agtatagtta ctgattttgg caagttgaaa
    14401 acgagaccag taaaaatttc tgaagaagcc tttaaagttt tgaaagttat aaaatttgaa
    14461 acagatcaat ctaatactaa tattattgct tcagctttga catggtatct tgataaaaga
    14521 aaaggaaaag cataatgaaa tgaggtaaga ctatggatca taaatcaaat tattcataca
    14581 aagaaaatta tatttggaag tatgtagtag ccgtttttct actggtaggt ggaattattg
    14641 cattggttaa atgggctata attcctaatg ctttagtatt tatcaattgg tttgtcccta
    14701 atttttggag tttttttggc tatatattga taatctggtt tatgtttaaa gtactctctt
    14761 ttttctggtc gcctgtatat tctttgcttg gaaagtggtc gtacctaatt ttaatagcga
    14821 cagctattta tatcattatg cagattaact aattatgcag attttagaag atattaaaat
    14881 ttattggaaa aggataatag gctatacatt agttcttctt gtagtaaatt tattcctttc
    14941 gatgatagcg ttggtctttg ttaatcaaag aaaagacaat gtaactgaat tagtaacgtt
    15001 tatttcgttt ttcataagtg ggatttttgc tcctttcttt gaagaaacct taatgagagg
    15061 aattatccaa aaccaattgg aattaaaaac aaatttgtct acaagaagca tatatataat
    15121 tgttgcaatt ttgtttagtc tatcccactt aaatttatat tttattcctt attttatgac
    15181 gagtttaatt ttgtcttttg tctatgataa ttcagataaa aggctgattg ttccggttac
    15241 tattcattgt ttttacaatt taattgtaat actgttaagt gtagtttttt atacttgaaa
    15301 aaaatagacg aaaacctaaa aatacaaggt ttttatctat tttttttatt ttgtttttat
    15361 ctatcaggtt gatagaaatt gtcataaatg atataattaa gtatgaactg atttagtaaa
    15421 aaaattaaag gagtgatagc tgttggcaag atcaagaatt gctaaaattg aacagactaa
    15481 aaaggataaa aaaatttcta aaaataaaac aaaattcttt aaagctgaag atgttaagag
    15541 gatagcatgg tctgtgaaaa catttgatga agatcgttat gttaaagttt caatgaatgg
    15601 tctatttgta cagcttggta acttcagtaa ttttaaaacg attgatgaac tttatccgga
    15661 aataagaaat attgtggata gtaaaggttt aatcgtggct aaacggaaat caagaaactc
    15721 tggtcttgct tactgtaaaa ataaagggat catgattccg gcttaaatca gtgaaattgt
    15781 tctttgaaaa cttaatacta ctcgtactgt agcaatgttg ctatgttaca gataaaagcg
    15841 taaggctaat aagcaaaata gcaaccaagc atactgttat ttcctttgcc aagaggtatg
    15901 taaatacgtt agcaatagaa gtgataaggt tagtatttca cgccaaaaaa tacaaaagtc
    15961 gatccattga aactactaat tatgaggtgg cgtaaatggt aattattcag aatttctatc
    16021 taggaagaac ctatgaaaac cgtcctagag atcagaatat tgacactaaa aaattcagca
    16081 cagtaataaa tgtgctagat acagggtaac tctttactac aagaaatgta gtaaagagtt
    16141 gttatgattc tttattacat ttctttctaa aggaagtgtg ataatgaaaa aactaaaact
    16201 gattagcatt gctctattca gcctaatcac tatgtcaacg gctcgccaat caattgtttc
    16261 ggctgaagga acgtctacga aagcagtagt agaagagtct ggcgataaaa aagttgctat
    16321 agacgacaaa gtgaaaaacg aagcggaaaa agcgactgtg gttcaagggg cagacggctt
    16381 gatgtatgtg gtcgttgatg aaaatgatcc tgaaaaattg ctagaagctg aatctccttt
    16441 gaaaaatcaa caagaaaata ccggcgctgt tgaagtcggt gttgatgaaa agagacaaga
    16501 aaaggctgat aaagctaacg aaaaagtgaa aaactttgac gatattgatt acaacgatat
    16561 tagttcgttg cagtcagcgt tgaatgatcc gaaattccct tttttatcgg aagatgaatt
    16621 aaatgaaaaa ttgcaaaaga caaagaatac atttgagtct gaagcgctaa tgaaaaagac
    16681 aaggggatat ttcagtcaaa ggattttaga gttaagcaat aatttaaatg acgtaccgaa
    16741 aagagcgaaa gtgagtcggc atgctttagt tagtaaccgt gcttcacaag taagtgaaac
    16801 acgaataaac cctccaaatg gttatccgtg ggtgatttat ttaattagga gcaatggtta
    16861 tagttataca gaaaattatg ctattagaag aactattgat gggaaagaag ctttttgttt
    16921 acaggccggt gtacaagcga cgaatacata cactggttca acaagtggtt atctttctaa
    16981 ttcgcaaaga gaaatgatta gttcgatttt atcagcatat aaagaattag gcggttgggc
    17041 taataatgat gccggaaaac aaagatggat agcaactcaa atgcttgttt gggaaaacag
    17101 taatgaaaag cctaaaagta taactgttac gccaaattgg aaaaacggag ctactaagtg
    17161 gaaaaatgat ttagtggctc gtgcaaatgc tattagagta agaacaaaat gggattctac
    17221 gtctaagacg gttgatgagg gagataaagc aacctttaaa gtaactaata cttatggaga
    17281 tcataatttg catgtgaaat ctgtatctgg tggcggcaaa gctaccataa gcaatggtac
    17341 tttaactgtt gatactacag gagccactgg aaacaaaatc actgtagata tgattaaagg
    17401 ttctcaccct tcagacgcgc accctacaac ggtatggagt aatggttctt atcaaaagct
    17461 tgttaccggt tctttttaca ttagtacttc tgttacggta aatgttaaga gaaaaggaac
    17521 tgttgaagtt ttaaaagttg attcagaaac aaaaaaacca ttatcaggag caacatttag
    17581 atttagctac tcaggtaaaa caaaagatgt tactactgat tcgaatggta aagcaaaatt
    17641 aactgaaagg ttgaaagctg gaactgtagt aaaagttaag gagataaaag ctcctaatgg
    17701 ctaccaacta gattcaagcg aattttcaat tacagttaaa gaaaatcaaa atgttactac
    17761 cacaagaacc aataagaaat ccacaggttc tgtagaaatt gaaaagatag gcgatttaga
    17821 tggattagga ctaccgaatg tagtattcac gatttataat tccgataaca aagttgtaaa
    17881 agataactta aaaacagata gtaatgggaa aataaaagtc gatgaactgc aatttggtaa
    17941 atattatgca gtagaaaaac aaggtgttac tggttatgat cccgatggta aaaaatacaa
    18001 ttttgaaata agtcaagata ctccttttac aaaaccggct aaagtgaaag taacaaatat
    18061 ttatgaagta tccataagcg aaaaagtatc ggacatgaat gaaagtcagg tattaaaaaa
    18121 taattggtct gctgatccaa acgattatct tcaatatgac attacaactg gaaatctaaa
    18181 aaaatcggga gaaagaaacg tccaaagttt cattatcgaa gggttttacg acaataagaa
    18241 tgtagatgtg tcaaaaagtg aagtatatgt tggatcaaca aatgtaacaa actcttttga
    18301 cattaataac gatactaaca atggaaaagt aattgctaag gcgaagacaa gcgtattaac
    18361 gaataatgat ttttataata agtcctataa tttacggatc actatgaaaa ttaaaaaatc
    18421 tactcttgaa aacactgaaa agcaaaaaaa tttaacgatt gttaaaaata gtaaagttac
    18481 tgtcggttca aaaatctcta aatctgctag ctctaatgat gtagaaaccg ttttatattc
    18541 aagaaaagtt actatcaatc atattgatga aaaagacaaa caccttttga aacaagatat
    18601 tgattataaa tacgatgggg aaacgtatga atataaacct agaaccgatt tatttgataa
    18661 agatggaaac aattataaat ctgatgtaat ccataaaggg aaaattgatg gaaaagatat
    18721 agttttaaac actccctatc atattccggt actttctgtg aatgtggatc ggattcaaat
    18781 tgatacggct agagctgtta aaaatggcta tttacctaca aaaatagaac taagtaaaaa
    18841 agaagaatat gaaaaagaat tagaaaaaat tgtattcaaa gttaaaatta cagatataga
    18901 taacaataaa gttgtttatg atgaaaactt taaatacaaa gaatttaata gtcatatgtc
    18961 gcttgattta cctacagaat atttaacaaa gaataaaaaa atcaattata gtgttgatat
    19021 tcttttagtg gataatccag ataaaaacaa gttcgaaact gaaactaaag atttaagaac
    19081 gatcggttat acttcttctg aaaaagtttt aacaaacaaa gatatgacaa ataaccaagt
    19141 caactattca gcagtagtta gaacagtgaa agaaagagag aataataatc cggtcaaaga
    19201 gttcaatgag agtatcaatt ataaatttac tgatagcact aaaacaaaaa caggatatgg
    19261 tatatcagtt gatttagagc caacatatag aaatgaaatt gggaaacaaa tagatatgaa
    19321 agtctatagt tatccgatga atgaattgat tgacagcaaa attgacgaaa tctatcaaag
    19381 tgggggaaaa gaaacagaag ttaagatgga tcgcttaaag aatgatggta aagttgagtc
    19441 gggtattagt actcaaaatc tttcattcca atttccacat atgaatatcg aaagaaaaac
    19501 tggaaatata tatgctgaca gtcaaagaaa tgatgaatct attaagtatg aattgatcga
    19561 tggcggtaga aaattatatg tgcctatttg gtgtgatttg ggaaattatt ctattgctat
    19621 caaaagtagt aactttggtg gtaactatat ctcgttggat atgaaccaga acatagatgt
    19681 ttatgcttat atgtatgcaa cgatagatag tgaaacaaaa aaagatgatg aattactgct
    19741 tgaacctgtt tatccagagt ctactctacc agatggttgg agcaaaaatg agattgattg
    19801 gctgaataaa taagtttgaa aagtttttat ctatctgata gaattaaata atgatatagg
    19861 gatggtgata gaatgagggt tcaaagctat ggtaacagtg tctttgatgt taaaagagaa
    19921 tttcaagatt ctagaagaaa aaccaaaaag ctgatagctt acttcattct atcagctatc
    19981 gttttctata ttgtcaagtt tgttttggaa ttaaactcaa tagtattcac agatatggtt
    20041 cataaaatgt taaatggaga acctattaat ttcaactttg attacatgct tgaaaaagca
    20101 caaagcaatc aaattgtggc ttttatcgtg agtatctatt attttattga aaaatctatt
    20161 ttttctttaa aagatttttt ctttgaaatg cttaccaaac taacaacgtt ttacaataaa
    20221 atttcaaaaa attaaggagg aagtttgaat gttagatcaa aatacagaca gaagttggtg
    20281 gatgattggt gccgtgatcg taggtgccat cttaatcggg acagctaaag tagcttttcc
    20341 cgaagtgttt aatatcgtca ttacattttt caaaaacatg atccctacaa acttaggata
    20401 gttccactaa aaaattcacg tagtttgatg cgtagaaaaa taataaagaa tgaaaaaggc
    20461 tacataaagt gatttatgta gccttttttt tggatggaag tgatgtaatg ctaagagata
    20521 tgcccaaaat gattctttta atgtttgttg ggttcttttt aattttagtg attgcgtact
    20581 attcattaaa tggctataca caagattcgt ctgtgaaagg tatgcaagaa acgttaagaa
    20641 ctacagcaat agcaaacagg gatgatagta ttcgagtaga aaaaggacga tttgctttaa
    20701 ttaagtctga ttttgaaaaa gattttaaag aaaaatttgg gaaaagtaaa aatctaaata
    20761 atgaaaccgc tgattataaa tttgattatc ttacagatgg gaaggacggt attaaagcaa
    20821 ttaaagtgaa ggttgaaagt ggatcaaaag aatatcaagc aacttgtatt ttaaatgttg
    20881 caaatgatta gaggtgtgaa atttgcgtgt tgtagaggaa aagaagattt ctccaaaaat
    20941 cgaggaaact cctaaaagta aaattaatat cgcaagtatt attaaaaaaa atggaattaa
    21001 agaaaactct gaagcgatag aaggaaacct tgatttttta actaagcttt tagaagaaga
    21061 tagtggaaat tatgaaccac caattgaaga tgcaaaatta aatatgattc gtgatgattt
    21121 aaccagaaac tattcccaag aagttttaca agctttaact gatgatgaaa ttaggcgaaa
    21181 acttgtacaa gttgttttga aagaacatgg tactttcttt aaaaaagata aagaggttgc
    21241 agaatatgta gtacgtgaat gtattggaac agggattatt gagcgaatta tgaccaacga
    21301 tgaaattaca gatgttggtt ggaatggctc tcaacttagc attgaaacta actctaacaa
    21361 atggttgttt gacggtgata aattaaatat cacgcaagag tatattgaac gtgttatttc
    21421 taaatatgct gttgtaaatg atcgggcttt taatagtggt aatcctatca tggatggaat
    21481 gtttaaaaat gttcgtatat cagctacaca catagataat tcaccagatg gctctacgtt
    21541 ttctatgcgt gtggcaaggc ctagattagc attgaataaa gaaaactttg aagattttgc
    21601 tcctgattat attttggagc tatttgagaa aatgatgaaa acaaaagcaa atatctgtat
    21661 atcaggggag acaggtacag gtaaaacgga acttcaaaaa ttactgctaa gttttattga
    21721 taatcatgat cgtatgatta tgattgagga cgttcaagaa actcacgcta aagaattatt
    21781 tccggataaa gatattttct cttggatcac tactcccaaa aaagcaattt cagatttagt
    21841 aaaagcttct cttagaaata atccacgatg gatcattgtt tcagaaacac gtggttctga
    21901 agcttatgaa atgcttcaag cggttttgtc aggtcactat gttgtaacga cacttcatgc
    21961 ggttaatgca cgtgcgatac ctagacgttt tgtaaatatg tgtgcaagtg gttttaaaat
    22021 aaacgaaaat gcggttgagg aagacataaa tcgttatttc gattttggtg tccatatcaa
    22081 aaaaacagtg gttgatggta aagtgatccg ttatttgaat gaaattgttg aattttctgc
    22141 tagtgaaccg actacagttt ttaagcaaaa atttatcaat ggaaagtttg tcattgaaaa
    22201 tggtagtctt tccgaagatt ttaaagaaaa aatggctgaa aaatttatta cgtttgaatt
    22261 tcctgaagat caaactaata cagaagaatc acttcctgaa gaagaagagg tgatttaagt
    22321 tgaaagtaca ggctatgaca aagcgaaaag gtctcatgga tgtttcggaa ctaaacgcct
    22381 atcaagtagc gtatggtaaa ccgttagatt atagagatta tttgaactat gttggattac
    22441 cttgtttgtt tatgggtggc ttttcttttg ctttatgtta ctactggtgg attgctttga
    22501 tttgtggagt aattggaggc gtatatggct ttaaagttat aatgcctaaa agtattaaac
    22561 gctcttatga attaaagagt ttacaggaaa gaaataaatt tattaacaac atgactcaaa
    22621 ttttgaccga tgatagtaaa acagttacta gagcgttatc tatagcaaaa cagcgaacaa
    22681 aaggtgaatt aagagaagat attcaaatct tagaatcacg tttacaaggt gctgataaat
    22741 ttcagattgc tgaagctttt cgtgaaatca acaataaata ttatagtgat gttgttttta
    22801 cacaatactt tgagcaattg gaaacagcta tttacgaagg tagaaataat tcagatacta
    22861 tgaagcaaat aaagagctat cataatgatg tgaaacgtaa aacagaaggt tttatgaaaa
    22921 tcaaagacgg ctatcttcaa gatatgaagc aaatgatgtt tattgtagct gtttttattg
    22981 gagctataac ttttgctttt ggtttttcta ctttctatga aggttttgct cgatcaccta
    23041 tcggatgggt atttggatct atttactttt tgattatggt tagcttcatg aagtcatttt
    23101 tcaaacatta ttttgatgat gaaataatga gtttgggggt aagtaattaa tgaaagttaa
    23161 ggctttaaaa aagaaaagaa aatcaagtat tagccccttg aaaattacga aaacagaaca
    23221 taaaagcttt tggattaaat tactaggtga tgtttattat caaaaattac gtgaaatgaa
    23281 caattccaat attgcgatta ttaagtggca aaaacaacgg ttaaaaaagt cattgatttt
    23341 tatcctagtc ggattcttaa tgtatctatt tttagggaaa gaatggtatt acttagccgg
    23401 tggaattgct acttcagtag gtttttatgt ttggcaagca aaatcaatca atggtatcta
    23461 taatcaattt cggtttgaac gacacttgca atttagtaaa tttacacggc tattgatccc
    23521 ctatctgaaa caaaaaaaag atggcggaaa tttatatggt gtttttgcaa aaatcgtaaa
    23581 aagactagat tatgataccg ataaaaagct attaatgaag cttatgcaag aaatgacaga
    23641 tcagcctaac gatattagac cttttacgga atatgcagaa cagacttctg gaacagacat
    23701 gtccgtatta tttatgtcta cagtttatga tattcgacaa ggttcggcag atttggatgt
    23761 tattgaagag ttggatcgtt tagcttctga agagttaatg gccggaatcg attcaatcat
    23821 tgactataag tcgaggcgtt ttgtcttctt tcctacaaaa attgcaatga cttcatttat
    23881 tttagttgtc ggttttgcag taggcgttct tttcatgaac ctaaaagata ttaactttgg
    23941 gcaataaagg aaaggagaaa gtcaatgcaa gaacaatccg ttatggaaat cattaaatgg
    24001 tttataggtt taatgatgat tatggcaatg gtttctatag gacttttttg tgttcaatta
    24061 caagatatta atactttcaa gcaacaagta aattatcaaa ttgaacgaaa aggaggtctg
    24121 acgacagaag ctgttgaagc aatcgacaaa tattcggcta ctaattatga tagacgtttt
    24181 acaattgaaa gcgataagtt aaatcagaaa gtatcttatg gagaagaaat tgattatacg
    24241 atcaaagcaa ctattccaat tcaaatttta ccgcttcctg atgtaacttt atcgtttaac
    24301 ggaaatagtg tttctcaaat aagatgagag gaaggataaa atgcaagaga ataatgtttc
    24361 cagaataatt tatttgattg gcggattgat aattttatcc ttagctattg ccggtcttgt
    24421 agagcattgg ccggaaataa agttattaat aagaaacttt tacgacaata aaatgattaa
    24481 aatgtaggag gtatagattt ggaagcaatt caagaaaatc gtaaggataa tcaagaaaca
    24541 agtgaaaaaa acaaaaaaaa aagaaaaaag aaagtagata aatttacgga aatgaccgat
    24601 aaaatcattg aaaagaaagg acttaaacct aaagactttg accgtcaagc aatcaaagaa
    24661 gcacgacaaa aactgtatga tgattttgtt aaagaaaaca tatcacagct tttagactaa
    24721 catttagggg gaaataaaat gaaaaattta gttatcagca agtttgcaat gttaccaaga
    24781 atggattttt tcgataatgt aagtaagttt atgtcaaata tgacttcaaa actacaagga
    24841 atttcactat ctgtaattat cttttgtatt gtggttactg gtttgatgtt tcttttcgga
    24901 gaagggccaa gtcgtactgc taaaaaatgg ttaacttata tcgtgattgg ggcaataatt
    24961 atcttcggag cttcaactat cggacaaacg atcaagtccg ttggtggttt ctaaggggaa
    25021 gcttcttaga actaaaaaat tcgcaagtat tgcatgaaag agcattgagt gattaatgct
    25081 cttttttatt ttgaaaaact ataaactaag gagatttaaa ctatgaacca acgattcgaa
    25141 tataattttg aagatgtaga acctaagtta ctgaaaaaag gaaaaggatt aaaaaagaaa
    25201 aataaatata ctctcaaaca agcagaagca ttagtaggat ggattcaaca caattggtca
    25261 gacaagacaa caattacctt gatctgttca gacacagaag aaggaacaaa gtatgctttt
    25321 gatggaattg aaattactcc attttcgatt ggcggacaag aaaaattatt gtttcctgat
    25381 attgaaggac aaattttaca agcgccggac agcatgattt ccgatcctaa taaactgatt
    25441 ttggatatta acgatcaata caaacacgaa ccagacgtag cagaaccaac aaaagaatca
    25501 aagtcaaaat taaatttgaa gctcccttca gtagtattac catttgctaa gaagaaaaat
    25561 aaacttatga acgaattgat tgaaccagaa gaaacggata tttatgaaga agaattagaa
    25621 gaacaagaag agatcgaaga attagttgtg tcttctgaag aaacagaaga agtagaagaa
    25681 attgaaactg tttctgaaaa tgaagaagaa acagaagaaa tctttgactt tgaagatgaa
    25741 gaagaagtgg aaaatgtaca gaaaggcgat ctatctacaa gtagtcaaaa tgggttggaa
    25801 gctgtaaatg atccacaagt tccaccatat atatcttcac aaactcccaa ttactctcca
    25861 cagtatcaag cgcctaatgt cttacaacca ttaagaaaac acgaaacagt gcagttagtt
    25921 acgcttaaag agtactgtga tttgggagaa gaaattgaaa cttcaatttc tcaaatggtc
    25981 gaaaagttga aaccagaatc tttattcaaa ttcataggga ttccttctac aggtcttaca
    26041 aatactcgta ttgatgaata tagaagtaac catgctatgt tgcgattagc tgaagtaaaa
    26101 tttgaaaatt taagagagca ttattcacgg caaattattt cttttaaagc agaagcccta
    26161 gatcgtttaa gaactgcggt agatattgct tggaagaagc cttacgattt agatgtgaag
    26221 aaaaacaagg ccgaagagtt atcaaaaatg gaagcagaag cagaagctaa attaaatgag
    26281 ttcgtgaaac gtcaggaaaa caatgtaaat gataaaatca aaaagtttga gatcgaacaa
    26341 gaaatagatt taaaaaactt tattgcaaga caagaggcag ataaagcggt atttattgct
    26401 acagagaaag atcggactca aaatttaatt gattctaaag cggaatcaat caatgcagat
    26461 ttacttgaaa caaaagataa atttattgat gaagaaatgt acaaaatgaa aattgaaatg
    26521 aacaaaaatt tatttgatgg caagcaaaaa attaaatcag aattggctac tgaactcgct
    26581 aaggcaaatg ataatgtttg ggaaaatgcg ctgaaattta ttcaagaaat tcaagatgaa
    26641 attgaagcta aaacaccaat ttgggctgct gaaatcaagg agtttaatag tttagaagaa
    26701 caagaacatg aacgtatgaa gcaaactaaa gaacttcaat taaaagagga aagtattgaa
    26761 atcaagcgtt tggaagctga aatgaatttg aagcgtatgg aagaattaga tcatgaaaat
    26821 aaaatgctta aaattaaact tgaaactgcc ctttcaaaaa atgagttatt agctatggaa
    26881 caagatacaa agcaagtggt gaatggatca aacagagttg gtgcacttaa tttatttagt
    26941 aaacgttaaa ggagaacgga tatgagtgtt tttaataata aagttatgtt agggaactgt
    27001 tatgtgaacc acattggttt ttacgatgga ggaacataca gagttttatt cttacgttta
    27061 tctgttttta gttactcaaa agatggaaag gggcattatg aaaatattaa tgcacaaatt
    27121 tcttgtcctt tagatagaaa tggggaaacc acgactacaa gtagtcaccc taaagccttg
    27181 atgaataaat ttatctttga aaagttggat cgcaatttgg ttgaggggat gaagataagt
    27241 attcatggaa atattcgtgg aacagaacaa gtgcttctta acagtggttg gaaaaacttt
    27301 ggtcaattat cgcctttaga aaaagaagaa tatcaaaaaa ttcctaaaaa tgaattagta
    27361 acaagaaatc aaacatatat ctatatagaa gaggtaagta tgccagaaaa agaagaattt
    27421 agaaagtctc aatctaaggt aacaaaagaa gatgtggaag ttgcagaacc gaatcaagca
    27481 gatgaaattt tatccgatga tactgatcca gtgaatgatg aaggagaggt tattgaagtt
    27541 tttgaagctg aaattatcga agaggaagaa gaaattaaaa gttttgataa aagaatgtat
    27601 cgagagaaac caaaaggtta tgtgaatttt gaagatatgt attatgacga atattctaat
    27661 gaaccaccga tcaattagtg ggggtcaaat atgaagctag tacaaaacaa tgaagtgaaa
    27721 gaaataaaaa acggctttgt taaaaactcg aacaaaattt tgggaaagct gaaaaaagta
    27781 ggtagtttca aaaaaaataa atatcatact ggaaaaattg agggagaaga tttaccaaaa
    27841 agtttacaag ataaattgaa tgttccgctt gtatttatag gtgttttttt aggttcaata
    27901 gtttttctag caataacgta cttattgaac tttttaaaag ctttgttagt tgcaatcgga
    27961 cagtcagaaa gtgggctact tggtgtagag ttcgatccta agtttagttt ggcatatcta
    28021 aaaccacttg gggatacgaa acaatacttt atgtgtgctg tggttgcggt aataggagtc
    28081 gcttatttaa tatatgggaa attaaatcat gaaagtgaga aaaatcttgt ttacggtcaa
    28141 aaaggagatt caagactttc aactatcaaa gaaattaaga gagattacca tgagatacca
    28201 gaaaaaacag aagtgtatga tggtattggt ggtgtgccaa ttagtcacta tcaagataaa
    28261 tattatattg atagagacac agtaaatacc gttgttttgg gagcttcacg atccggtaaa
    28321 ggggaaacat ttgttgttcc tttattagat aatcttagcc gagcaaaaat acaaagtaat
    28381 atggtcgtga atgatccgaa aggagaattg tttagcgctt caaaggaaac acttgaaaaa
    28441 cgaggttatc gtgtattagt gctaaatatt gatgatccac ttgaatcaat gagttttaat
    28501 cctttacaac tagtaattga tagttgggct aacaaggact atcacgaagc tagtaagcga
    28561 gcgaatactt taacttcaat gctctttgct tcaggaatgg gtacagataa tgagtttttc
    28621 tataaatcag ctaaatcagc ggtcaatgcg attattttaa cgattgtaga acactgtttt
    28681 aacaatgatt gcattgaaaa aattacaatg tacaacgtgg ctcaaatgct gaacgaatta
    28741 ggaagcttat tttacactga tccaaagact agaaaagaaa aaaatgcttt agatgaatat
    28801 ttcaatactt taccacaagg gaatcaggcc aagattcagt atggttctac ttcatttgcc
    28861 ggtgataaag ccaaaggttc gattttatct actgcttcac aaggtattga aatgtttaca
    28921 agtgatttgt tcgggaagtt aacaagtaaa atgtctattg atttgaaaga gataggcttt
    28981 cctaagtcca tacaatttaa agtcaatacg aatttagttg gaaagaggat tagtatttca
    29041 tttttgagaa aagaaaatga tgtaattaga ttaattaaga agtatcgagt gaaagtaaaa
    29101 gctttagggc tatgtgtttt aaattttaat gaatatcttc aggatggaga tatgttggat
    29161 atacgatatg aagaagagaa atcgagagca tggtatcgta ttgaatttcc caaaaaacaa
    29221 gcaaatagtc atgatacttc tttagtcact aaaaaattca agtcaggtaa aaattattct
    29281 gacttagaaa tcagcacctt acgattaaaa tacacggatc agccaactgc tgtgttcatg
    29341 gttattccag attatgatcc gtcaaatcac gtacttgcaa gtatttttat cagtcaactt
    29401 tatacagaat tagcaagtaa ttgtaagcaa acaccggata aaaaatgttt taggcgagtt
    29461 catttcttgt tagatgaatt tgggaatatg ccggctatag acaatatgga tgggattatg
    29521 acggtatgtc taggaagaaa tatgcttttt gacttagtga ttcaatccta tagtcagcta
    29581 gaaacaagat atgataaagc ttttaaaaca attaaagaaa attgtcagaa tcatatttta
    29641 atcatgtcga acgatgagga aacgatagaa gagatttcaa aaaaatgtgg tcataagaca
    29701 acaataaata gaagtgctag ttctaaacat ttagatactg atagctcggt cactagttcg
    29761 gcagagcaag agcgagtaat tacagttgag cgtgctagtc aattgattga aggggaacaa
    29821 attattttaa gaaaccttca tagacaagat acaaaaagaa ataagattag accatttcct
    29881 atttttaata ctaaagaaac aaatatgccg tatagatacc aatttttagc agaagacttt
    29941 gatactcaaa gagatattaa tgagattgat attgcatgtg aacatatcaa tctatcttta
    30001 caagataacc aaattccata tgcaaggttt atcaaagatt taaaaacacg tttggagtat
    30061 tcaattatta ataatattcc tattagtgaa gaagactatc aggattatct aaatttatca
    30121 ggatcacaac aaacaattaa tgaagaagag ctgttaaaac tggtaaatac ggaagtaaaa
    30181 agtcaagata tggaaggtca agttttatca gaacaagaaa tgaaaattaa tatttatcta
    30241 aaggaaagtc aaaaggaagc aatagaatta gtaaaagtaa ttaatggaag gttagctgat
    30301 gaaaattcag cagatatggt tataaaaacc attaattcac aaatccttga tacgcctttc
    30361 attcaatctt taatcaatga ttctatagct attcataatg ttcaagagag taaggatcaa
    30421 attatgatcc tagaacaaca attagctaat gcttatgagt tagcagtgtt taaaacgaaa
    30481 aattcaatac tgaataataa aattatcaag ttgaaaaatg ctatgactaa gctagcaaaa
    30541 gcaatttaga gagaagggaa gaaatattga ctgaatctat taattggaga aaactaaatg
    30601 tgcaatggtt aaagtataaa tggccaatca tagtttccct aataatcatt ctatttatgg
    30661 cctatccgca acgagttttt gcgttgccgt ggattacaga caataaagag gtattaaaat
    30721 ttttaacaaa atatcaagat tatcttcagt ttactaaagg tggttttgga agcattgtcg
    30781 ttcaaagttt atcgtggggg ctgattagag gtgcatattt tgtttgtaaa tcagcagaaa
    30841 accttgttcc acaatcgcta agtttgttta gctttgttga aagcagtagt ttaggtgctg
    30901 tttatcaatc tgtattaaac acggtggttg taggattaat gatcctttca ttgatgtttg
    30961 ttggttacaa gatgattact ggaaaaggaa cagtggattt aaaatcggtt ggaatgaacg
    31021 tagtgatgtc tatagcatta atacttttaa tgccgacttt gattggatca acagaaaaac
    31081 tttcaggaat aatgtttgca aagactcttt ataatgacgc aactagtatc aataatcaag
    31141 atggcggtgt agcatggtca ttgattgagg acggtgtaac tgatttagta tatatcaata
    31201 aaaacgatgc ttatgatcgg ttgggtaaag atggcgtaca aaaaaatgcg ttaaaagaaa
    31261 agaatttctt ttcctacgat ttcagtgaag taatcacagt tgatacagct aaagatttag
    31321 aagatgataa taaaaaagct gaatatcttc aatctaggtt gacaccagat ggcgaaggaa
    31381 atatgcaagc cgttaagatt gatgatggtt ggatgtcgat gttctctgat agtttcaaag
    31441 gagggtacta caggtttact aaaaatactt ttgcattgac tttaggatta ctttcgttag
    31501 ctgtagccta tgtttttagt atttttatca tagtcaccgc tattttagaa ctggcattta
    31561 agcgtgtgtt aggggttctt gtttttgcaa cagatattga gacaggacag cgttcaaaag
    31621 ttgttctatc agatattcta cagtgctatt tgactgtagg ctttcaagga tttggattat
    31681 ccatgtttgc aatgtttgtt tcctatttag gaacaggcgg agggtcttcc gttaatccgt
    31741 ttattaaggc tgtagcttat gtatgtgccg tttttgtttt aatcaaaggc agtggaacag
    31801 tcatgagata ctttggtgtt gatattgggc tcaaagaagg ctatgggcaa cttgcttctg
    31861 cttttggaat gggtgcaatg ctgtttagaa aaggatcaaa tggatttaat cgtgccaaag
    31921 gaagcggaaa cggaaatgga tcagacagcg gagaaggaga agatcgaaaa ccagaaaaga
    31981 atttcggtga aactctatca aaaaaagctg gcaaaactgg aagagctttg ggatatgccc
    32041 atgaacgtgg attatcaggt ttagcttcag atggagctac aatggctagt gaaagagcaa
    32101 caaaaccatt taagagtatg cgtgatatgg ctaatgatac taagaataag ttcaaagaag
    32161 gtttagatga tggtacagtg tccgctatta ataaaaatag caaacctatg ttagctaaaa
    32221 ataaagaaga tgaaactgga aaatatgctg attccatgcc aacacgtctt tcggatagaa
    32281 aagatggtgc taaggttgaa aatgccgata gaattatgtc tagttctgaa cgtatgcgtg
    32341 aagcaatgaa aaataatgct gaatcgaata ataatcctgt aagtgcaatt cagcaaaaag
    32401 ttcaacaaga tattgaagaa cgtaaaaatg ctatgcacgg tcaagctaag tctgctgaag
    32461 aattaattaa tcagaagcga caagaagcta aatacacgcc tgaagcaatg aatcgtgagg
    32521 aaatgttaag gaaacgtgta gaagggcgta caggaactaa tacggacgaa aaagaagcgt
    32581 tgaccaaaga aagaatccaa gaagctaaaa actcaaatac cggattagaa aaattggtca
    32641 aagaaaatct acaaaattct acaagtagtc aaggtggtcg atcagtagat gtccgagaaa
    32701 atattcaagg ttcattgaat ggtcatgtcg gacggaatgt tgatgtaaga gagaatttac
    32761 aaagttcttc aaatggtcaa ggtactaaga caattggtgt tcgagaaaat ctgcaaagta
    32821 gcagtacaag tcaaccaaaa acagtagatg ttcgagaaaa tgtacaaaat tctacaagta
    32881 gtcaagggtt taaatcagtg gatgttcgag agaatgtgca aggtagcagt gcaagtcaac
    32941 caaaaacagt agatgtccga gaaaatgtac aaagttctac aagtagtcaa ggattcaaaa
    33001 cagtagatgt tcgggagaac gttcaaaaag atagtggaga aatgaaagaa aaaacacaaa
    33061 aaatcaatat cgttgaagac agaaagtcag cgaaaaaatt tgattcaaat catgaaacag
    33121 tgattattga tagtgaaatc cgtgaaaatg ataagggatc aaaaccaaga cgaagattca
    33181 cttatgaaga caacgaatta ttcagagata cacttaatga tcctaatcca cttttcgata
    33241 atttaaatta aattaaaagc cggcatgagt gattatgccg gctttttatg aggtgaaaat
    33301 gatgtataga aatcccaaaa atataaaaca agagataaag ctatttttct tctatttagt
    33361 cgatttagga atagtagccg gaagcgtgat ggcaagtgtt tactttgcaa aattaatgcc
    33421 aatttcacca atgatgaaat ttgcactgta cttattagca tttgtagtgg gtgtttggat
    33481 gtgcgttaga acgcctaatc accctaaaga gcgaaatatt ttaatgctgt attatctctt
    33541 taaaatggat agaaacagat accacgaagt agagtttaaa agaaatagta gggggaaaat
    33601 tgaattatga ttgttgctga aagtaatgaa aataaattaa gtggtgtttt tgacaaattc
    33661 ttagaactag ttattccaaa agataaagat atgtgtgaac ttttaccata taaaaaaata
    33721 ttgaaagacg gaacgttagt gactaatgac aataagtatc aagccttttt taaagttaaa
    33781 acaactgact taacttctat ttcagaagat ggatttatgc gtatggtaaa caaactcact
    33841 tatttaaatc gagtatattt agaaccatat aaaatttatt cattaactta tcctactgaa
    33901 acagtaaatc aagcgattta ttggaagcat agaatacagg aggcaaagag aagtttattg
    33961 agtaataatg atcccaattt agaaacgtat ctgaagtgga atctaaagct agcttacgat
    34021 aattatgaaa gagttgatct agtatcgact ttaccagagt tgatgttcgt tatttgtgtt
    34081 tatggaaaaa cacaaaaaga agtgaaaaat catgccgatg taatgaaaca ggccggtggt
    34141 agagaattag atttacaaag aattactgaa ggggatttaa tcaatgtgat aactaaattg
    34201 atgaatccca atacttcttt ataaggcggt gcttattatt atgttaaagc actgtagaaa
    34261 aggattttgt aaagtaatta aaggtaaaaa tgctgctgat ttaatctttg aatggaaaga
    34321 atctaattta attaatgtac gtgggaaaaa tggaagcgga aagacagaaa gagtgatggc
    34381 tagtattgat aattcaaggc ctagatcaag agcattagta ataactgatg aaaaaaatca
    34441 ctataaaggc atacgaacga tagaaaaaaa atatttaact aacaatgatt taaaagtagt
    34501 agatgatatt ttaaatattt atcctgattt taatttagtt gtttttgatg aaacaattcc
    34561 tgtgacagaa ataaaaggat tctatcaaag cttttccaat ctagcaaata aatatgagga
    34621 agttctgttt gtttggatta cagaagaaga tagtaatagc aagtcagcgt tctttagtga
    34681 aaagaacgct tttttacatt ctatttaaaa aggagaattg aacatgattg taagtaaaaa
    34741 actagcaaga aatctagtaa gtgaagggta tgacttaaga ttagtagaaa agtatcaacc
    34801 gagcggtgga attaaatttg atgagcgtta tatttctact ggtgatggat atgtaacttc
    34861 gattgctgtt attgagtttg cagaagatgt aaatagtcga tggttaacgg atataatggc
    34921 aattccaaat actattgcaa ctttcgatgt atgtacggcg gataaagaag acttattaca
    34981 caaaatcaat acgtctattg gagaattaga ttaccgatca acaaatgaga atagaacaac
    35041 tgacaaaaca gacgctttac tagataaata caatttagaa gattttgcac aagaaattac
    35101 gaaacgtggt gaagttgtca aaactgttca tgctcgtatt tttgtttata gcgattcttt
    35161 agaagaatta gagaaaagaa ttagtgagat tcgtaaagat ttggctagtg tcaatcacaa
    35221 ggcaattgtt ccgcaattta gaatgaagga tgaatggatg tctttatttc aagatggcat
    35281 ggaacaagaa tcaaaattat ttgccaagaa aggcttaact gttccggcaa aaaatattgg
    35341 tggcggtatt ccatttcacc acaagagttt gaaagatcca cgtgggtttt atttaggaac
    35401 tacgtcaact ggtggtgctt ttatatttga tccattttat tctacgaagc aaagacggtc
    35461 gtttaacggc tttattttag gaaagatggg ttttggtaag tcaactttaa ttaaacagct
    35521 acaggaaggc ctacaagcga aaaattgttt tattcgagga tttgacaagt caggtgaatt
    35581 tgaaggcatg gtgaagaaag caggcggtgt atacgtcgat ttaggcggtg gtgatatggt
    35641 agtaaatcca ttgcaaattt atgcaacagt catgaaaaaa gatcaatttg gaaatgatgt
    35701 tgtagatgaa tcaaagagtt ttcaaaatca tatcactaag tgtagtaatc aaattcgctt
    35761 tttagaacct gaaattgata cggcaactgt acgtgaatat actttgatgt tacaagactt
    35821 ttatattcat tatggaattt tgccaaaaga atggagagaa gcgagagacg acaacgaacg
    35881 aaatcaatta aatacaaata tttgtaactt gcctaatgat tcatatccaa tctatggaga
    35941 gtttcttaaa tttattgaaa atcaacaatt caaaattaaa aatgctactc ctgaacgtgt
    36001 ccgttctatt gagctaatta agcttatcgt tacggatatg tgtacaactt atccgcaaat
    36061 tttcaacgga gtaacaacaa tgccaaactt tgatacaaca aaaattgttt actataacat
    36121 tgattctatt agtaaaatga gtgccccagt attccattgc caattattta cagcgttaac
    36181 gactatttgg aacagtgcct tgcaaaacgg aaagattcaa aaagaaaact ttaaaaaata
    36241 tggcagtgat tattataagt atgcacaaga tttcatggtt ttgatcgatg agtgtcacaa
    36301 tggtgcgacc tgttctgcag tgaaaagctg tgggttgcaa gtagtctaaa aactattgta
    36361 ataactctta taacgagaag tcaaatgagt gggtaacgcc acaaagggct tccactgata
    36421 ctccgacatg caacaagtag tttatgcaga ccaacgttgt gtgaagctcg gtgaagtcgg
    36481 ctgaaggata ccgtaaggta aaagaaatag tgaataccac gaaagttctt tagaggtaaa
    36541 gggtgtatcc gataagtcgg gtgtccaaaa aaacttaata tggtgagtat gtacaaacgt
    36601 actgacgaac tagcgaatgt actgtccgaa aggcatagct cctagaaatg ggagagacag
    36661 tgagcaaaaa atcactcatt gtgctaactt gtggttgagt aaaagtcgtt gttatgaaag
    36721 accatgctgc gttacaggcg taggagaagt tagggggcaa aagctagcat ctaagttaag
    36781 gcatgtggat agatataagg gaacagggga agccatcaac atggagagtg catactcgat
    36841 gaagtggtag taagaaatat gtgaatgaca aataacttac tttagtgatg gtgaaagtag
    36901 agtcacgact gatgaaggtt ctgtaatgga actggaggaa caggctcgat tcgtctgtaa
    36961 aagtcatgaa acccgttcaa ccatgggatt ctcgtatgac taaaaaggtc acgagccaat
    37021 tggagcgtga taaaccatga caaaagaaac aagtccaaaa gataggaagt tgcggcatgc
    37081 agaatattat ggcatgacgg aaatcttcga taagatatac tccaaaagtt tgaagggaga
    37141 taatttcaag aatctaatgc agattatcat tagaagcaac aaaccgtaga agaatggaag
    37201 atatcgtggt tgtgtagcaa tccagtgctt agtaagagag caacgattga atttgcggac
    37261 aatcgaattt caaaattcat cgctcaaaag ggaagatgtg cagtaacagg tgaggagctt
    37321 atcttatctg aaatgcattg tcatcatatt atcccttatc atgaaagcaa aagtgatagc
    37381 tatgaaaacc tagtgattgt tactgaggag gttcatcggg taatacacgc tacacaaagt
    37441 gaaacgattg aggaacttct aaaatatcta aaattaaatc caaaacaaaa agaaaaactc
    37501 aatgagttga gattaaaagt tggtaacgaa gaaatatctt aataaatatt tgtaggacgg
    37561 gaaaacagaa tgtcttttat agacgaggga acgccgtatg cggtgaaagt cgcacgtacg
    37621 gtgtggactg ggggaaaaga cggagataat atcaaactct tacctatcag tatttatcaa
    37681 ttcaaataac aagtatgctt gtgaatatgt actaagtttt gagcgagaaa tgcgaaaaat
    37741 gcgtgcaggt gtttattttg caactcaaac gcctgaagaa attatcccta aagattctgg
    37801 atcagaagta gcagatgtga ttagaaacat ttttaatcta tgtactttta aatgcttctt
    37861 taatttagat tctgcattgt tggaagacat aaaaaaagtt ttaggaaata caattactga
    37921 tacagaaatt atgcttttac cagaattaga agtaggacaa gctgtagttc aaacttccag
    37981 tgaagacacc tatatgatta attttgatcc atatccagag caaattgaac gattcgatgg
    38041 tggtcaataa tagaaatcgg aggtgaattt aatggagcag aacaaaaata ataatgttgc
    38101 ttcaacactc gctcgtcaag ggatgaagca agtatcaaag aaaataggtc ttgctttaaa
    38161 aataaaaata ggggtagtta taggactgat aacattggtt ggccttttag ttataggttc
    38221 tttagctaca ttacaaggaa cacaaactgc aactaataca ggaggtgcag aagtcattgg
    38281 tggcaacaaa ccgttgtcac ctgaagttca aaaatggcaa aaaacggtag aaaaatatgc
    38341 tgaaaaatac ggaattaaag aattagtacc ttatgcttta gcaattatgc aatgtgaatc
    38401 cggaggtaaa ttgccggatt taatgcaaag tagcgaatca gccggattgc ctgtaaacac
    38461 acttcaatat gaagaaagta tcgatcaagg gctaaaacat ttgagtaatg tgtataacat
    38521 tgctaaaagt tatggcatgg aaagtaacta tgatggaata gttcaagctt acaattacgg
    38581 aatagcttac atgcactact taggaaaaaa caaaaaaaca catactatcg aaacggctga
    38641 agcctactct aaaaatgttg ttgctccaag tttaggaaat actacaggac agacttattc
    38701 atatgtaaat gaagtatcaa ttaaatatgg aaaaacatat ttgtatttaa atggtggtaa
    38761 tttttactat gcagagttag ttaaacagta tatcggtggg ggtagtggta atccggctaa
    38821 tccttcagaa ttttggggaa aaatgaaaac agaaatggaa aaatatcaag gttggcctta
    38881 tgtttggggc ggtaaaaatc caacgacagg ttttgattgt agcggattaa cagcttatct
    38941 ttatcaattt agcgccggaa ttacaataga tagttataca gtaacgcagt atgaagcaac
    39001 tgaagcagta tcaattaaag aagcaaaagc tggtgatctg attttcttta gaggaacata
    39061 tggagcgcct gatttcattt ctcacgtagg tatttatgtc aatgaaacaa ctatgtatga
    39121 cagtaattca agcggaattg gttatcacaa ttggcaagat tcatattggc aatcacatag
    39181 tccagagatt cgtagagtca aaaaatagga ggaagaaaat agatgattaa gagaaaaaat
    39241 gataataaat ggaaatatat ttgtggtgtt ttaattatta ttttagtttt aggtggattg
    39301 ttatctcaac ttcatacaag taacattcaa gcaaaaaata aaaaattgga tcaagaagtt
    39361 acacaactag aagaacaaaa tagcaagtta agtaaaaata ttagtgatct aaatgcaaat
    39421 gtagaagcga acttaactaa tgatgatggc agtgaattaa ataaacaaat tgctgaagtt
    39481 gctaagaaat ttgttgagct atatccggta tatgatattg aaaaagtaga agaaaagaaa
    39541 gctgatttag agaaaatagc tactccttct gtagctgatt ctatcgtgcc ggacgacatg
    39601 attacaacga gtaaaaagac tttagaaagt aaatctacta ctcaaaaagg agaagcatat
    39661 tcaagtgatc caacattcaa aagtaaatat aaagattcaa aattatatac gaattatgtt
    39721 aacgccaata ctattaatta ttttgctgaa gtaaattata aaacagaatc ttctagtgga
    39781 gatacagaaa atacagtcta tatgcttttt gaagtaacca ataaagacgg ccaagtgttg
    39841 gtagataatt atgaaatcaa gtacttaaaa tagtgaggtg aagtatatga ataagaaata
    39901 ttccattcat aataagaagg aaccaaataa aaaaaataag gcacaaattg acaaagtata
    39961 taaaaaaacg aaaggagtaa aattatattt aggtgctata cttggatttt tagcaatagg
    40021 aatgataatc gttttttctc cttatgtgat ggggaaaagt tatgattttg aaactgtaaa
    40081 aatgagttca gcccaaaatg taacgtcttc tttgaatatg tatgttgctg atatggaaat
    40141 aaatagggaa gccggactgt ttaaattagt attgcggtat caagatgata caggtactaa
    40201 atcactaagt aatattaaaa gtgactataa attaaatttt ataacgaaca aaaataatga
    40261 agatgttaag acaaaagttg taaaattgtc agatgaatac acggtaattt attataaaaa
    40321 tctgcctaaa gattttggtg taatttctgt gacagttaac cctagatata tttatcctga
    40381 attagaacct tcaaatgact taaaagaaaa ggaaataaaa ttctatgcag tagacaaaga
    40441 tattaaatca aatgctaaat tggaagttga aagtacttct gatttgcaaa aagataattt
    40501 taaatatcag attaaagcta tagaaaattc tataaaagat gagaaaaaat caattgaaaa
    40561 aatgaattta gcaaataaag tagtgcaaaa agatattgat aaagctaatc aaaacttaga
    40621 atttcaaacc ctagacgaac aaacagatac aaaaaatgaa atcagttcta tgcagacgac
    40681 tattgaaaat aataaatctt caatagagga aagtgaaaat aaaatcaaac aatttgagga
    40741 aaaaataaag caactagaaa agtctgcaag ccgatttgag tgatcgtgtt taaattattt
    40801 taagggagtt tagagagaat gtgtaattct attgtcacta ttcaagagaa agctgaagaa
    40861 gaattaatga gaattgaagc ggaatataaa gaaaagagaa aagcgattaa gcgcaaaaaa
    40921 aatgcagagc ttaaaaaata taaagaggaa caagcgttaa aattaggaat gatgttgtgt
    40981 aaatattatg attgctatga tataaacgaa gtgctaaaaa aagcgaattt aaaccaattt
    41041 tgtgaataga aaagagagtg gcaaggtaaa acttgccact ctttttttgg gcgtaaaagc
    41101 tttagttact atgaccaaaa ctacggacga aactatgacc aaaagtaggt actatattat
    41161 gaccgaaaat aggtcgaaaa tggatttttt tgtgatagca aaaaatatga agctattttg
    41221 aaagaaaacc agttggcaca gccaacttag ccaccttcct ttaggaaggt gctatcagtt
    41281 ttcccttatg ctctttgtat taattccttg gtcttgtctt taaatcttta attttccttt
    41341 ggactttgat ataataatat ataccagata gataaaaaca gcttgaaaga ggtgtgtgta
    41401 tggatgtttc aatcagagga attgatccac aatatgtaaa agagattgat aaaaaagtta
    41461 ataaaattca agaacgtacc ggaaaaaagt ttagtaggaa tgactatttt ttagcaatca
    41521 ttcgccaaga tagcgagatc gatttgattg actataaaaa gtcagaattt gatttagtag
    41581 ttgaaaaact tttattgtca aatgaacaaa tggtagaaag tattagcgag ttaacttcag
    41641 tttatgaacg cttattcaat tttttaatta gcgaaaggag tgatttaaat aaatgaacta
    41701 cccttatttc aaagtatcag caacagaaga tgtaaaagaa aaattcaata agtgctttga
    41761 agtaaacaag tcagtatttc aaacaaaatc caatatgttc cgttatgttg tttcaaattt
    41821 accaatgtta acaaaagcca atcaaaattt ccgtgatcca gaaaaagaag agttagctaa
    41881 aaacttagaa gaagcaaaat taaaaattag cgaacttgaa acgataatag aattgcaaaa
    41941 acagcaactt gaaaacttta ataaaaaaga agacagtaca cataaagatt atagtgaaca
    42001 attaaatagt atagaagagt ctgtctataa actattaatt aatagtggat tagctagtaa
    42061 agaattagaa gaagagcgtg ctgaaccaga acaagaaagt agtcgtttgg gagagggaac
    42121 aatgtttagt tcaccgtcat taagatttac aacggattga acactaaaaa attctaatgc
    42181 aacttagcat taagtacaaa accgcctgta gaaaaaattt ttgaaaatgg tgggtgatga
    42241 tatgactgaa catatcttta acagaaaaag tgcgagcatt attcttaaag caaaatttga
    42301 aactggaaaa agcaaaaaga ataatcacat ggtagaactt caaaaatttg tagattatat
    42361 ttccagacaa gaggctatta ggcaagataa actagatcat gattattcag aagatgaact
    42421 aaatgaatta gctagaatag aaaaagcttt ggaaaaaata gaacaggaaa cagatcaacc
    42481 agtgattaaa gatttacgtg aaatggataa atatattgat tatatgacac gtaaaaaagc
    42541 tatcttagaa aatgtagata atgaaatagt aaacggagca tttagcaata caaaaagata
    42601 tatcactaaa aaagacattt caaaaataaa agaatcggtc atagaagcaa aaaataatgg
    42661 atcggtgatg ttccaagatg taatttcatt cgataatgat tttttagtaa gggaaggata
    42721 ttataatcca gaaacaaatg aattaaatga aaatgttcta tatgaagcaa caaagtctat
    42781 gatgggaaaa atgcaagaaa aggaagaact agttgatcct ttttggtttg caacgattca
    42841 cagaaatact gaacatatcc atattcatgt aacagctatg gagcgtaaaa atactcgtga
    42901 aataatggaa tatgatggtg ttttacaagc taggggcaag agaaaacagt ctacgttaga
    42961 cgatatgatt tttaaattcg gtagcaaaat attagataga acgaacgagt ttgaaaaaat
    43021 ttctaagttg agaaaagaag ttcctttaga acttaaacag tctgtaaaag attctttgat
    43081 tcaattatat gtagaaaata attcaagata tgacaaagaa ttagtaaagt acctaaagga
    43141 attaaaaaaa gaaataccta gtacaacacg tggctacaat gagcttcctg aagaaacaaa
    43201 agaaaagatt gatgaagtca caaattatat gacaaaggat aatccaaaaa gaaaagaata
    43261 tgatcgtatg actaaagaaa ttgatgagct atatcaaaca acctacggta aacgctacaa
    43321 tccacaagaa tattatttaa atagaaaaaa agattttaat gctcgaatgg gtaatgctgt
    43381 agtaggacaa atcaaacttt taaagcaatc tgaagaaaaa aatttgaaaa gtaatgaact
    43441 taaaaatcta ttagacggaa aaaaattaaa cgttaagttt gatagagaaa aaccagaatt
    43501 taaaacgaaa tatgctaaac aaagttatga tgatttccaa aaaagattag aagaacgaca
    43561 attagcacgt gaaaaaaatg aagtccactt caagaagatt tctgaaaaat ttaaagataa
    43621 aaagcttatt agaaaaattg atagagtaat caatgatgat ttaaatatgt atcgtgcgaa
    43681 aaatgattat gaagtagcgc aacgaatgat agagcaagag aaaatgagac aagcacgtga
    43741 atttgaaata ggaatgaatt agtagaaacg gagaatagaa attatgaaaa acttcgatat
    43801 agtgtgcagt aatacaaaaa atatatattt acgtgagcta cttaacagtg attcggaaac
    43861 tatagaagat gtaaaaaaaa tcatagtgtt gtttgaaaaa gaaaacatgg agctagagaa
    43921 ttgggggctt tttgaaatac cgattagtgg gaattactgt ttttataatt ggaagacaga
    43981 agacgatgta gcttttgcaa attacttttt tgataaaaat tacttttccc cattatatat
    44041 agataagcat agtaatgaac aagttgcttc ttcaataaaa gaagcaataa aattggaaag
    44101 agtgaggaaa tgatatgatc gattttagaa cggttatgga taaactaagt aatggagatt
    44161 ttcgcgtatt gattgaacta tacttaaatg taacgtctac agtcaaagag tttttatatt
    44221 ctaatcccaa aacagcttta gtattagttg cagtactgat agtttttgct gtgatctctt
    44281 ttattaagaa aatgattccg ctattaatta taggtgctgt gttgatatta ggtttgtatt
    44341 tccctgaagt tttggatcaa ataaaaaata tattttaggc tctaaaagtt tccagtagaa
    44401 aattttgggc tttgatattt gttttaagcg gtttgaaata gaaatttgat aaactacatg
    44461 aaaagacatt atataagagt atctgtgtat tggaataaaa atatgataat ataaaattat
    44521 atatcagacc gataaaaaag aggtgcttat aaatgaaaaa gttaagagtt attgcaacaa
    44581 tacctatgat ttttagtttt gcgctattat tatctgcatg tggcaaagaa gaagctggtg
    44641 ctaagtcaaa tgaagcacat aatatctcat tcatagatag tgcagaacaa aaagactcac
    44701 gttgttggtt gatagtcgaa acaagtagta aaaataaaac gcctattgat aaaaatgaat
    44761 atgtaaaagc ggtgatccaa actaaagatg gcaaagcaaa agtatttaaa acggatatgg
    44821 aacagcttac attggaaaaa gtttctaaaa tgagtgatga agaaataata gaacaagcat
    44881 tgaacgctga taaacaaaag tttaatgata agaaaaaaag cgatattgat agctataatg
    44941 ccactttaga ttctgtaaaa acagaattag aaaatgagga aaaacaagag tttcaaaatg
    45001 accaaaaaat tgctgatttt caagatagta tacctaaaat acaggcggat atagaagaga
    45061 tcgatggtgt tcaatattca gagccggagt ggaaaatggt atcagcaaca attaaaatgg
    45121 ataatgaaaa caaatcacct tcaatggaaa ccgttaaatt atcttataaa tatttagata
    45181 gtccaatttg gaatttaaat agttttggtg aagtttcgtc tgaaggagaa ttatcttatg
    45241 aatctactag tatggatttg aagttatcaa ttccagttgc cacaacgaaa gttttagata
    45301 atttttattc aggatattct aatgatgaat tggatcaact tttgcttact aaagtagctt
    45361 ctaaagataa caaagttcaa ttagatagta aaggtaaaaa cgtaagtata gttgagtaga
    45421 tggtaaaata agaagggata agatggttac tataactatc ttatctcttt tttatttgca
    45481 ttaagtcagt gaaattagat agaagagttt ttatctatct ggtataattt aattaggtaa
    45541 tttaacttac ctaaaaaaga aaggagatag aagatggcct ataaaaaagg aaactggaag
    45601 ccgaaaacga aagagcaaaa acaaaaagag ctagacgatt taattaaggc ttccaacagc
    45661 aaaatcgagc aatatcagtc taaccctgaa gatatgatcg agtttgccaa gttcatgtct
    45721 aaaatacaca attacagtcc tttaaaccta tcgttgatcg atgagggatt tgaaggagca
    45781 attgctgtag caagttatga tggttggaaa aaactaggat ttcaagttaa agcgaaagaa
    45841 aaagggatag gcatttatgc gcatgctccg gtaacggttt ttattgatga aaatggtgaa
    45901 gaaaagacgt taaaagaagc aacaagcgag caaaaagaaa aaatcaaaaa tggagaatta
    45961 agaagcaaaa agatcaagca ttttaagaag ggttacgtat ttgatatttc ccaaactaat
    46021 gcaactgaag ctgatttgcc aaaaatattt cctaacaggg tatggaattt taatattgat
    46081 ggtgaattaa gtgttagtca attagaaaaa ggtgtaaatc atttggccga atctatgaat
    46141 atatctataa aagatatgaa cgagtctggt agaggtgaaa tgggaagcgc tagaggtgaa
    46201 tatattcaat atgttgatgg tagggaagaa attgtattaa attcaagaaa tagcagaaca
    46261 caaaatctta ctaccagtat tcacgaattg gctcacaaaa agcttcacaa taagaatgaa
    46321 cacggttctt cctactcaac accaattaaa gagtttcaag cggaaatgac ttcatttatt
    46381 gtttgtcaca attacggtat tgatacgtca gactttacta ttccttatat tgcaaattgg
    46441 actaaaaata atgaaaaaat tgatccaaaa aactttagac agataatgca agaagttaga
    46501 gaaacgtcta ttgactttat aagtacgatt gataagaaag tcttggaaga acagcaaaca
    46561 gcatttaatg cactaaaaaa ttcctttgtt cctaatgaga ataaagagca gatacaacaa
    46621 aaatcagatt tagaatttca taatttctac gatagtacaa tcaacgatcc ggatagaacg
    46681 atccacggta gttatttaga agcgatggtg gattattata gaggaaagta tggagaaaat
    46741 tctattgagc ttactcatag caattatgat gttacagcta aaataggaga aaactatgtg
    46801 acatattatt cagatacgaa acaatttgat gtatgtgatg tttatggtgt agtttttgag
    46861 aatccaagtg aaaataaaaa tgatcgttta ttattagatc gatcacctga aaattgtgat
    46921 tatgttgaaa agtttgttgt agaaagtttg aaagcttgcg agaatcatga actaaaaaat
    46981 gatacgttaa aattaagcga accgctaaga tcagttgtta taaatgaagc ggtttataat
    47041 ctatctgaaa atgctaacaa ttactataat gaaaaatgtt ggcaagaaga aattgaaaac
    47101 caaacaaata ttaatgatgt aaaagaatta aactcttgta tgactgcgga agatttttac
    47161 gaatctcata aacaagaaat cgaaaatacg attacagatt ttgaatctgt gtcaggaaca
    47221 aatttaagag atacaataga caatgagtca tataaagagg tggcttcagt ggtagcttat
    47281 aaattggttg caactaaagt aaaatatgaa atggatgaag gaactttcaa gataccagaa
    47341 aattctaact tggaaaagcc gactgtaaaa acagcagaac gttcttttga aatggagtga
    47401 aaaaattatg agtaatgaac aaaattatga aacaggcgga acttatcgcc tgtttcatgg
    47461 aagtatgaat aaatttgatg aatttagttt agatcataaa ggtttaaacg gaacagctaa
    47521 tggatttggt gtgtacttaa cacctaataa agaaatggct acaatgtacg ctgaacaggg
    47581 tagtaacgga aataatggtt tcgtatatga agtaaatgtt gaattagaga agccgatttc
    47641 tatgaatgaa cgcactatta ctgatgaaga gctttctaaa gtaatagata aattacaaga
    47701 aagtaatgat attttaaatg attacaatga tgttagttat tacggagaaa aagttgtaaa
    47761 aagagaagtg attgcttctc ttagtgagaa tgaaaatgac gtagatttga ttaacgacat
    47821 tggaaataca attggagatc atgaagctac tgctaaggca ttttatgacg ttgggaaata
    47881 tacacatatt attgcggaag aacagttaag acaaaaggat gtagttatcg tagtgttaca
    47941 gcctgataaa gtaaagattg aaactattca cgatttaaac gaggaacgga atagcttaga
    48001 aagtagtgag gacatgacag ataaatttgt tgggcataag gtttcggaag ttcccattcg
    48061 agaagttgtg ataaaagatt ttgagcaaga gctagaaaca actaattatt atgacaaaca
    48121 agcttggcaa gagcgcattg aatacttaga aaacatggaa gaaccagttt ccagattagc
    48181 attagatagt gatattaatg aattttatga tagtcataaa gaagaaattg aaacgaaatt
    48241 gacaaattta tccgaaaagt tagagatcga taaagaagaa ctgctaggtt ttccagtaga
    48301 tacttcttct acggaataca aaaaagctac gtctatcatg gcttacaacg gtgcaatgag
    48361 agaaatttat aatgaaattg aaaatgatac gtttgaaata ccacctgttt ctgaagaaat
    48421 ggagaataag attttgaaat tgactaattt tgaaaataca acaaaatttg aaatggagta
    48481 gataaatgaa tgatagaaca agaaaataga aattttttag aaacgcaagg tgaatatcgt
    48541 caaattaata atagtcattt tgtaatttgt gaagatgtac aaatcgcttt taaaatggct
    48601 ttgaagtacg gaaaaagtat tagaaaaaag ataattagag aaaaaaagag caagaagata
    48661 ggcttttggg agttatctct tagggatggg ctaaacttta ttttctgtac agaggattat
    48721 tatgaaaaat acaagtgtac cttatcgtaa ttttactagt gatggtctag taaagggggt
    48781 ttttgtttgg atttgaaaaa ggcaaaaaaa gtaagtatcg ttgatttttg caaacaaaat
    48841 gggataggtt taaagcaaga ttcaagggaa tactatagat tagaagatca tgattcttgt
    48901 gtaatcagtg atcgcaaaaa cctttttaaa tggaactcaa aggatttagg gggagatatt
    48961 tttgatttta tcaaagccta ctatgattgt tcatttaaag aagcaaaaca gaaacttgaa
    49021 gatagcgatt atgaagttca ttcgttcaat acaaaagtga aaaaagctcc gtaccaatat
    49081 cagaaagaaa atgaagtgcc ggtatctgtt gcaaagtctt atttagtaaa tgagagaaga
    49141 atcgatacag ctttagtgga agatttttta tctaaaggac taattaaaca agataaaaaa
    49201 ggaaatgttt tgttcttatg gaaaaaagat caagaaatcg ttgggtgtac ggaacaagga
    49261 actagaaaat tttttcatga aggcaaacaa aaggatgtta catggaaaaa aatacaagaa
    49321 aactctaaag agtattcagg atttaacgta acttttggtc aaccagataa aatgtatttt
    49381 tttgaaagtg aaatagattt gatgtcgtac attacacaaa agccagaaaa agccgaaaat
    49441 gctacgtttg ttagcatgaa tggattaaag gtaggtaatg tattgcatgg ggttacagag
    49501 cattataata agtttaaatc attgccttca gaaacagtcc tttgtgttga taatgataaa
    49561 gccggacgta cttttattga aactgaattt aaagaaaaag gaattggaag agaagggata
    49621 ggaatcagtg aagtaaaagt cgatgtacct ttgcgagagg gatttgattg gaatgataat
    49681 ttaacaagag gaaaagaagc ttttaaacgc ttcaagttag aagatgtatc aaaaatcgtg
    49741 aacttcacac ataaattatc tcttaatact cctgtatatg aaatggaata acaagaagaa
    49801 agtagttgat gtgttatgaa cgatacaata gcaatcttat cagattcatt aattgattta
    49861 gataagacgt ctacagacta tatgattatt gaagaacaac ttaaaaataa aaatccagag
    49921 ttcgatattc aagaaaaatc attgcgtatt gaattaccaa aatttaaaca aaaaaaatta
    49981 ataactattc tctttgagat tattgaacga tatgggctta cttattatca aatttggacg
    50041 gataagaaag atggccaata tacaaaaggg gtaagcatag aagccgttag agaagacgat
    50101 caagtaagta ttaaagcagt tcaaccctta atggggtata acgaagaatt attgaattgt
    50161 ttaaacgtct agtgtaaact aggcgttttt ttacattatt tggctacgaa tagacagtta
    50221 attaaactaa agaaaactat tgactacaag tagtcattcc tgtatgatat agccatagac
    50281 tacaagtagt caaagactca aacccttgat ttaataaaaa ggagagataa tagatggagc
    50341 agacaagaat gttttggtca gatcgaatgc aagatcactt ggattgtatt tacaaaacca
    50401 gagagcaatt aaataagtta gatactgtca gatattattt tacctacttc agtgagaatg
    50461 acgaacaaag atgggatatt tttcatgatg gtaattacga agaatttttt tacactgaaa
    50521 gttaattatt tgttgaaatg atgaaggatt ctatttgatg aaagggaacg gaaaaccgtt
    50581 cccctaaaaa atatccaaat gactacaagt agtcgtggaa ggagagcgga ataatggtaa
    50641 ataaaaaaga aacgtttaaa gtaggtatgg aagtacaggg cgttgttatt gggagcggag
    50701 agcttatcga gggagaagta attagtttgt tagctaatgt agcggtagtt aaagcaaacg
    50761 gaaaagcacc ggtagtgatg aaaaaatgca gcatgatgtg tcttgatggt ttaaacaatc
    50821 caataactca acgctttgag aacgtgatat aatagaaaaa agaagatttt ctactgggag
    50881 agattattat gaaagactat gcttcacgta aatttatcca cttagagcct atgaaagaat
    50941 tggttattaa tgggaatgaa tataatgatt acaaatcttt atttgtaaag gaacagccta
    51001 aaggtggtat tcggatgaaa aatttaccgg acttccgact tattgaagta aacaatttag
    51061 gaattataga agactattta gctaagttag atgaagcggt aaaacaatca attgaaaaaa
    51121 atggtgaaga ccatgtactt acggttgttt taaaagactt gaaagataga ctagaagctg
    51181 aagcagagaa ctttaataaa gactaataag aagggaatga gagatatgac cgaggctgta
    51241 aaagaattaa agaaaatgta tcctgatgtt ttgaatatga ctgtagatga ttttcacgaa
    51301 gccttaaaaa atgcagaaag tgaggaagag agaactttct accttgtact ctctagttat
    51361 gtgacacgag tagatcaaaa aaaagtaatt aatcagaaag attttaaaat atgattttag
    51421 aaaatgataa accatattat gtagttattg ggggcgttaa tggcgccggt aaatctacga
    51481 tttatcaaat tcaaaattca aaaagaaaag aacttgatac tgatagaatt aatgcagatg
    51541 aaattttgag gcgttttgga ggaaattgga ataaacaatc agatataaac aaaagtatgc
    51601 gtgaagttct gagagagatc gaaggtcatt ttaaagaagg aaaatctttt caccatgaaa
    51661 cgacttttgg cggtaatcca tatcccgata aaaagaggct tctaaatgct aaaaaattag
    51721 gttatgaatc gtttttaatc tatataggac tagattcacc agaaagagcg attgaaaggg
    51781 ttaaaagccg tgttgctaaa ggtggccacg gtgtacctga agatttaata agaaaaagat
    51841 acgaattttc tttaagaaac ttagcagagt tagagaaata ttttgataat gtaagtatct
    51901 atgataattc agatgagttt tcttatattt atgttaaaga aaatcataca gttgtagcca
    51961 ataatacgca agaatatgct tgggttccca aagctattca agagaaaaat gctgaaactc
    52021 ctataagcaa acaaattatg atggatatat ctcaagaaga gatgaatcca aaagaaaccc
    52081 ttgaaagaat atattcagca agtgatgatt ttattagtga tcggttttca aaagaagcgc
    52141 aagtcgatga tttttatagg aaccataaaa atgaaatcaa ggaacggatt ctatcaatta
    52201 gtttttctac aggggtatct caagatgaat tagtaggtca agataaaaga agaaattctt
    52261 gtaaattggc atatattaat agtgtaggtg agcttttagt aaaaactgat agtgagctat
    52321 taagtatgga attaaataga gatagaaata tccaaaaaac tgattttgaa gttgaataaa
    52381 agaagttgta gctgaatcaa ttaatagtaa ataaatttaa taaggagtgc gaaagcactt
    52441 cttatttttt ggataaagtg actatatgta gtcagaagga ataatatatt atttttagtt
    52501 tttgttttta atataattac tacaagtaga caattgatca ttgattatag tctaggaaat
    52561 atgttactat tattatatac cagatatata ataatgaggt gctaaaattg acaataataa
    52621 ctatgactaa aaaaatagaa gtatatgttg atggatcaca agaggaaaga gattcgtttt
    52681 ttggtttttt ttggaaaaat agtagagaat atgtaaaagc gctgaatatg gtatataaac
    52741 agctgatgtt tgaagaattg atcgaaaatt ctataaaaga attggatcat gagtatatta
    52801 aaagagagct aagtcttgaa gagcgaattg ataatttact aagtaatgaa gtgatcgatc
    52861 aaaagaaatt agataaaacg aaaagggaat tatctaaact acgaattgcg aaaaacaaag
    52921 aagccagaga cgttttgaca caagctatag gtttaaaaag tcaaaccaga atacgtgata
    52981 tagcaaaaaa attggacttt gattattcgg attttataga ttcagctaaa atgaaagcta
    53041 gtaaggattt tagcaatgat tttgttggaa ttgttactgg gcaaagaaca cctagaatct
    53101 atagaaataa aaataaatat ggattgttac cgttcagagg tcgggatatt aagattcaca
    53161 aagctgacaa gttttatatc tctttaccta aaggatttag gtttaaagta aatttaggta
    53221 gaaaaccaag aaaagccaga gatagcgctt taactttaga acgcattatg gacggtcaat
    53281 acaagttaaa ccagagtaat ctaatctttg aggggaaaaa tttatttttg aatttaacaa
    53341 tttcttttga aaaagattat cataagctag atttcaaaga aggagctgaa ttaaccataa
    53401 tgtttactga tttgtgtagc ggtaaatgtt tagttaacaa tcaatctgtg attgattttg
    53461 gtgacagcaa atatataagt aacttcaaaa ataaaattaa agcaatgaaa tcaagggagc
    53521 aaagccgagg agttttttct aaaggcggtc atggtcgaaa aagaaaatta gatcaagata
    53581 gatgggaagc cataaagaaa agagaaagca attttgttaa aacctataat aatcaatgtt
    53641 cggcaaaaat tattcaaaca gctatccgca ataagacgca aataatctgt atttctgaac
    53701 cagataaaaa ttatggggaa tgggcttatt atcagttgaa agaacaaata ataaataaag
    53761 ggaaaagata tggaatagaa gttaaaagtg agtagaataa gaaatcgttg atttggcaac
    53821 gaaatagtga ggggacactc actcactgaa gggttagctc tgtcaagttg tgtaaccaga
    53881 cggaaggacg aatattgttg aggttttaga accatgtaaa acaacacagt tctcaaatat
    53941 agattgatag attgatcttc cctaatctgt tttagaacca tgtaaaacaa cacagttctc
    54001 aaatgttacg gataaaccgt ttgcgggaaa tcaggtttta aaaccatgta aaacaacaca
    54061 gttctcaaat aaggctttat tgaattgatc agtagtttct gttttagagt tatataaaac
    54121 gacatggctc ttaaatagga gctaacgaag aaaaagaagg tactccgttt tggagttaag
    54181 tagaaataaa aaaatagaat cgttgatttg gcaacgagtt gaaaaatacg caaaactatg
    54241 gtcaccaagg gataaccctg aaactgatga tcgctatatc ttactagtag ttaaacagtc
    54301 taaatagtac tcatttattg tattgattct aagggaacct gcaataaatg agtactattt
    54361 tacttttaat tccgctatct atgtcattag gcaactaaat tgttattaat atatttacgt
    54421 ttactcgtat atttttagta acgcatctgt caaaacttta gaaaaattta ttttatcttt
    54481 ttcccctcta gctactaacc attctgggac tgtgacgttt ttgcgtacgg tctttttttg
    54541 gataaatgga gaaggatcac tttgaataag agaaacaatt ttgttattgc ccaaattatt
    54601 tagttgatga atatctgttg gagaaggaac tgaaatatct tcatcaatat agtaagctag
    54661 aatcccatca agaaattctt tagcattgga catagcttct tcaaaattat ctccttgtgt
    54721 tgctccagca aaatcaggaa aaactactga gtagccattt tcttcagcag aaaaaattac
    54781 agggtaactt tttttcattt ccaccactcc tttcgagtta atccaatgaa ctaaaggact
    54841 gggctatttc agccctaagt cctttagtaa cttctgctct gtcccttttt ttaaatcctg
    54901 attactatga acaggaatag gaacgggtgg gaatccttct ttggctacaa tatgatggct
    54961 gccagttatc ctcaccactt tccaaccatt tttcttggct agtttgagca tttttttacc
    55021 ggtaagtggc attcgcgact acctccttac aaatattatt atacgcatta tgcgtataaa
    55081 ggtcaagagt ttttacatta aaagtagaat gtaagtgtca caatagggta taccctattg
    55141 tatcatatgg taaagtacag tataataagg tttggaggtg taacactagg gtgtaacaca
    55201 atgtgaaatt tggaggtcat tttttgaaca agaaacagga tcaagaatat tatatagaaa
    55261 aattggagaa agagaactta gaactcaaag agcgaataag atactatgaa accaaattct
    55321 gtaaaagagg tgattgtatg aaaccaaatc ctgttgaaac aggtaaaaga attaaatcaa
    55381 ttcgttctaa ttttggaatg actatggagc aattcgctat tttaactgat tcatctaata
    55441 cgagtgctgt taataactgg gaacgtggtt ataacttacc aaataaaaca aaactaaaaa
    55501 aaatagctat actaggaaat acaactactg actggattaa atggggaaca ttagaagagt
    55561 atataacttc ataccttatc gatatagggt atgagctata tattaaggac tttccagaga
    55621 tacctcacaa agtctttaaa gacatccaag aaagatatag tgatacgttt tcgctaaata
    55681 aagactatga attattggat tctataataa aaaatatatt tacaaaatat tactcaaacg
    55741 gttgaattga tagatggact caaagaagaa aattcaaagt taaaagagaa gataaaatac
    55801 tatgaatgtt tatttgatgg tatagagagt ctgctgaact cacgaaaaaa tccctagttt
    55861 ttatgaatga ccgttttgta aatctgattg aaatagattt atatgatttc ggtatatgat
    55921 atacattagg aggtgtcgaa tggaaataaa tctttttgag gctggtaatc gaataaagca
    55981 aatacgagaa aaacatggat atactatggc agacttaggt aaactggttg atgccaatag
    56041 tcctagcaca attaacaatt gggaaaaggg aaataactta cctaatagaa agcgtcttga
    56101 aaaaattgca ctattaggtg gtacttctgt tgaatggata aagtatggag atttttccga
    56161 ttatgtttat cgcttgacac aaaatataga ggaaaaaatt cttaaagagt acggagagac
    56221 tacactgaac aactaccgtg aagctcttct agatgaactt acgattgaaa aaatcacata
    56281 cgaagaagat gcaaagatat tagcagctgc cgaaaaaatc aatacacaaa atatttttca
    56341 ggaggtgaag tacatgtatt ctcctgatga agattatcga aatatagaag tcaaaccaga
    56401 tttaggactg actgatgaca acaaaaatat taaaatgatt ggacaacgta taaggaaaat
    56461 aagaaaaaaa gagaatatta cattagaaga attcggcaaa ctattctctc ctacagctga
    56521 taaagctgtt ataagcaact gggaaaatgg taaaaacctt cctaactcag aaagaattaa
    56581 aaagattgca gaaattggcg gagtttctga actttatctt atgacgggtg tcgattcaag
    56641 cgtagcagaa tcaatgtatt ttctatctga agtagcattg gatgctttgg aacgtctgtc
    56701 aattgaggaa gtcaatagaa taattgaaag cttcgccggt tatcttaatg tgatttcaaa
    56761 aattgatgat ccagataagc gagaaatatc tctcaatgct atttgtcaac tatcacttct
    56821 cgataaaatg ggttgattca caaaaaatat tgaaagatta ctttactcac gaggaggctt
    56881 agctatgaaa cctaatctat cgttaactag tgaacgtatt agaaaaatta tcgaatccaa
    56941 aggtctgaca ttagaacgat tcggtgattt aattggcgac acaccaataa gttctgttaa
    57001 taattggctt agaggcgtgt ctttacccaa taaaaatagg cttttaacaa ttgcaaatat
    57061 tggaaacact agtgtagact ggattaaatg gggaactttg gaagaataca tagcttcata
    57121 ccttatagat tcaggttatg agctatatat taaagacttt ccagagatac cttacaaagt
    57181 ctttaaagac attcaagaaa aatatagtga tacgttttca ctagataaag actatgagtt
    57241 attgaatcct ataataaaat ttactatagg gggcgttact ttgaatagaa taaaatttta
    57301 tattgattcc agtaaaaaga ccattaaaca aattagtaca gaaactggta ttaactatac
    57361 aactcttacg aactattacc gtggtgagcg aaatcctaga aatactgaaa catggaatat
    57421 ccttgctgat tatttccatg ttcctgtaag ttatttg
//
LOCUS       DAIGSZ010000010        55992 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.010, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000010 DAIGSZ010000000
VERSION     DAIGSZ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.010"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            185..703
                     /locus_tag="NOB31_000628"
     CDS             185..703
                     /locus_tag="NOB31_000628"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI0972866.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            831..1514
                     /locus_tag="NOB31_000629"
     CDS             831..1514
                     /locus_tag="NOB31_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HCI0972867.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1823..1896
                     /locus_tag="NOB31_000630"
     tRNA            1823..1896
                     /locus_tag="NOB31_000630"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1857..1859,aa:Arg,seq:tct)
     gene            2055..2413
                     /locus_tag="NOB31_000631"
                     /pseudo
     CDS             2055..2413
                     /locus_tag="NOB31_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
     gene            2536..4167
                     /locus_tag="NOB31_000632"
     CDS             2536..4167
                     /locus_tag="NOB31_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HCI0972868.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4229..4870)
                     /locus_tag="NOB31_000633"
     CDS             complement(4229..4870)
                     /locus_tag="NOB31_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCI0972869.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRIIPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5056..5132
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5152..5460
                     /gene="rplU"
                     /locus_tag="NOB31_000634"
     CDS             5152..5460
                     /gene="rplU"
                     /locus_tag="NOB31_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HCI0972870.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5487..5831
                     /locus_tag="NOB31_000635"
     CDS             5487..5831
                     /locus_tag="NOB31_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HCI0972871.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5844..6137
                     /gene="rpmA"
                     /locus_tag="NOB31_000636"
     CDS             5844..6137
                     /gene="rpmA"
                     /locus_tag="NOB31_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HCI0972872.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6571..9378
                     /locus_tag="NOB31_000637"
     CDS             6571..9378
                     /locus_tag="NOB31_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0972873.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            9569..10060
                     /locus_tag="NOB31_000638"
     CDS             9569..10060
                     /locus_tag="NOB31_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0972874.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10163..11152
                     /gene="manX"
                     /locus_tag="NOB31_000639"
     CDS             10163..11152
                     /gene="manX"
                     /locus_tag="NOB31_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HCI0972875.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11185..11988
                     /locus_tag="NOB31_000640"
     CDS             11185..11988
                     /locus_tag="NOB31_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HCI0972876.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            12009..12923
                     /locus_tag="NOB31_000641"
     CDS             12009..12923
                     /locus_tag="NOB31_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HCI0972877.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            13006..13380
                     /locus_tag="NOB31_000642"
     CDS             13006..13380
                     /locus_tag="NOB31_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HCI0972878.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13519..13764
                     /locus_tag="NOB31_000643"
     CDS             13519..13764
                     /locus_tag="NOB31_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0972879.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13936..15000
                     /locus_tag="NOB31_000644"
     CDS             13936..15000
                     /locus_tag="NOB31_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCI0972880.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15246..15671
                     /locus_tag="NOB31_000645"
     CDS             15246..15671
                     /locus_tag="NOB31_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI0972881.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15664..16113
                     /gene="nusB"
                     /locus_tag="NOB31_000646"
     CDS             15664..16113
                     /gene="nusB"
                     /locus_tag="NOB31_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HCI0972882.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16210..17064
                     /locus_tag="NOB31_000647"
     CDS             16210..17064
                     /locus_tag="NOB31_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HCI0972883.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            17065..18402
                     /locus_tag="NOB31_000648"
     CDS             17065..18402
                     /locus_tag="NOB31_000648"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HCI0972884.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18407..18631
                     /locus_tag="NOB31_000649"
     CDS             18407..18631
                     /locus_tag="NOB31_000649"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HCI0972885.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18633..19523
                     /locus_tag="NOB31_000650"
     CDS             18633..19523
                     /locus_tag="NOB31_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCI0972886.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19532..20350
                     /locus_tag="NOB31_000651"
     CDS             19532..20350
                     /locus_tag="NOB31_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HCI0972887.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20457..20906
                     /locus_tag="NOB31_000652"
     CDS             20457..20906
                     /locus_tag="NOB31_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCI0972888.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20924..22606
                     /gene="recN"
                     /locus_tag="NOB31_000653"
     CDS             20924..22606
                     /gene="recN"
                     /locus_tag="NOB31_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HCI0972889.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22661..22777)
                     /locus_tag="NOB31_000654"
     CDS             complement(22661..22777)
                     /locus_tag="NOB31_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HCI0972890.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22850..23806)
                     /locus_tag="NOB31_000655"
     CDS             complement(22850..23806)
                     /locus_tag="NOB31_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI0972891.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23977..24345
                     /locus_tag="NOB31_000656"
     CDS             23977..24345
                     /locus_tag="NOB31_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HCI0972892.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24515..24946
                     /gene="mraZ"
                     /locus_tag="NOB31_000657"
     CDS             24515..24946
                     /gene="mraZ"
                     /locus_tag="NOB31_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HCI0972893.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24967..25926
                     /gene="rsmH"
                     /locus_tag="NOB31_000658"
     CDS             24967..25926
                     /gene="rsmH"
                     /locus_tag="NOB31_000658"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HCI0972894.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25931..26332
                     /gene="ftsL"
                     /locus_tag="NOB31_000659"
     CDS             25931..26332
                     /gene="ftsL"
                     /locus_tag="NOB31_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HCI0972895.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26333..28525
                     /locus_tag="NOB31_000660"
     CDS             26333..28525
                     /locus_tag="NOB31_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCI0972896.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28551..29513
                     /locus_tag="NOB31_000661"
     CDS             28551..29513
                     /locus_tag="NOB31_000661"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HCI0972897.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29527..30888
                     /locus_tag="NOB31_000662"
     CDS             29527..30888
                     /locus_tag="NOB31_000662"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HCI0972898.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30914..32002
                     /gene="murG"
                     /locus_tag="NOB31_000663"
     CDS             30914..32002
                     /gene="murG"
                     /locus_tag="NOB31_000663"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HCI0972899.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            32017..33237
                     /locus_tag="NOB31_000664"
     CDS             32017..33237
                     /locus_tag="NOB31_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HCI0972900.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33393..34718
                     /gene="ftsA"
                     /locus_tag="NOB31_000665"
     CDS             33393..34718
                     /gene="ftsA"
                     /locus_tag="NOB31_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HCI0972901.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34741..35982
                     /gene="ftsZ"
                     /locus_tag="NOB31_000666"
     CDS             34741..35982
                     /gene="ftsZ"
                     /locus_tag="NOB31_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HCI0972902.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35999..36676
                     /locus_tag="NOB31_000667"
     CDS             35999..36676
                     /locus_tag="NOB31_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HCI0972903.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36690..37289
                     /locus_tag="NOB31_000668"
     CDS             36690..37289
                     /locus_tag="NOB31_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HCI0972904.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37304..37591
                     /locus_tag="NOB31_000669"
     CDS             37304..37591
                     /locus_tag="NOB31_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HCI0972905.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37640..38422
                     /locus_tag="NOB31_000670"
     CDS             37640..38422
                     /locus_tag="NOB31_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HCI0972906.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38443..39150
                     /locus_tag="NOB31_000671"
     CDS             38443..39150
                     /locus_tag="NOB31_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HCI0972907.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39412..42210
                     /gene="ileS"
                     /locus_tag="NOB31_000672"
     CDS             39412..42210
                     /gene="ileS"
                     /locus_tag="NOB31_000672"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HCI0972908.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42259..43785)
                     /locus_tag="NOB31_000673"
     CDS             complement(42259..43785)
                     /locus_tag="NOB31_000673"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HCI0972909.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43800..44447)
                     /locus_tag="NOB31_000674"
     CDS             complement(43800..44447)
                     /locus_tag="NOB31_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HCI0972910.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44631..44960)
                     /locus_tag="NOB31_000675"
     CDS             complement(44631..44960)
                     /locus_tag="NOB31_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HCI0972911.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45137..45865
                     /gene="sfsA"
                     /locus_tag="NOB31_000676"
     CDS             45137..45865
                     /gene="sfsA"
                     /locus_tag="NOB31_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HCI0972912.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45881..46894
                     /locus_tag="NOB31_000677"
     CDS             45881..46894
                     /locus_tag="NOB31_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0972913.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYRVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46894..48171
                     /locus_tag="NOB31_000678"
     CDS             46894..48171
                     /locus_tag="NOB31_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI0972914.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48234..50936
                     /locus_tag="NOB31_000679"
     CDS             48234..50936
                     /locus_tag="NOB31_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0972915.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            51088..51405
                     /locus_tag="NOB31_000680"
     CDS             51088..51405
                     /locus_tag="NOB31_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0972916.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51435..51755
                     /locus_tag="NOB31_000681"
     CDS             51435..51755
                     /locus_tag="NOB31_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0972917.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51863..53323
                     /locus_tag="NOB31_000682"
     CDS             51863..53323
                     /locus_tag="NOB31_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0972918.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53391..53612
                     /locus_tag="NOB31_000683"
     CDS             53391..53612
                     /locus_tag="NOB31_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972919.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53643..53825
                     /locus_tag="NOB31_000684"
     CDS             53643..53825
                     /locus_tag="NOB31_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HCI0972920.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53825..54238
                     /locus_tag="NOB31_000685"
     CDS             53825..54238
                     /locus_tag="NOB31_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HCI0972921.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54361..55542
                     /locus_tag="NOB31_000686"
     CDS             54361..55542
                     /locus_tag="NOB31_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0972922.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(55613..55777)
                     /locus_tag="NOB31_000687"
     CDS             complement(55613..55777)
                     /locus_tag="NOB31_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972923.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
BASE COUNT        18527 a         9442 c        12070 g        15953 t
ORIGIN      
        1 atgttagggt aaacgttttt taaactaacg tcaattattt ataataaaaa atgagataaa
       61 gatgaggaaa tagaattaga aacatataat tattaaaggg aaacattttt acagctataa
      121 tttgaaaaaa tttatcgtta ttatatgatt aagaaggatt gaataaagaa agaagttgaa
      181 aacgatacct gattacaaaa aaataacttt tataagttct ataacgttga ttatattttt
      241 aattcttatt cttctcgtcg tcttggttcc ccgaattttt ggtttgactc cttatattat
      301 tgaggacaaa gaaatgagtc catattatgc acaaggaaat ctgatatatg tacgaccgaa
      361 aaatacaaat gagattttag tcggagatat tattacatat tatgaaaatt caggaaaaaa
      421 aatctcgacg cgtcgcgtaa tagccgttga aaacaaccac gaagattttt atacaaaagc
      481 tgatacaaag acttatattg agcctggagt agtaaaaaag agaaatatta tcggtagtcc
      541 catctttcag attccatata ttggactagt cctttcaaaa acggcatttg catggattca
      601 ggggttattc tttacgattg ctttttgcct aacaggaatc acagcatgga atacctttgt
      661 agagttgaaa aagaagcgga gacgaacaca gaaatttttg taagaatgtt aaaaacataa
      721 atgtattcca gagatccaac gactcttctg aacatgaaac acgagaaaac actcatgcag
      781 cttgtagatt tagtcagttg ttcgtataat gtgtgaagag gaggagtagt atgcgcaatg
      841 aaatgatgca tcgtcctgta gtcaaagaag aactattgga ttttatgcgt acccagcaaa
      901 aaaaattacc gggtgagcta ggcaaactgg aagaagaagc tcatgtagca gaagtaccag
      961 ttattcccca tgaaacagtt gtatttttga aatttttact tggacagctt cagcctgaac
     1021 gaatcttgga gatcggagca gctatcggtt tttcatcaag tgtcatggcc acgacaatcg
     1081 gagaaaacgc tcatgttacg acaattgatc gtttcgatgt catgatcgag aaagctaaaa
     1141 aaaactatga acgtctagga ctgacagata aagtgacttt gcttgaaggt caagcagcag
     1201 atatcttgcc ggagttgtct ggtccgtatg actttatttt tatggatagt gcaaaatcaa
     1261 aatatattga atttttacct gaatgcttac gtttgttaag aaaaggtggc gttttgatgg
     1321 tagatgacat cttccaagga ggaacgatct tgctcccaga tgaagagatt ccccgtggca
     1381 aacgagctat ccatcgtaaa ttaaatgaat ttcttcgtgt tgtgatggat catcccgatt
     1441 tgacatcgac aatcttgcca ttaggtgatg gtgtgatctt aatgacaaag gaatcagaaa
     1501 caatcgagtt gtgatacatg attatggcag cctgtagata atcgattgaa tcgagggctc
     1561 aattcgaact tgatgtaaaa gtttctatat ttgtaagtca attaaaggat acaggaaatc
     1621 taaataaaca ggagtagcat gaagtcaatg tagctcctgt tttcaattga taaccttaga
     1681 acagctgaag gagaatgtct cgttttaaaa gattgattta gtagttgggc caaaataatt
     1741 cattatttgc taattaaata actatttcgt attgacagaa gcaatttaat tatctataat
     1801 tattgatgtt ccgctgattc ttgtcatagt agctcagctg gatagagcat ccgccttcta
     1861 agcggacggt cgggggttcg aatccctcct gtgacgctaa aaaaccgtta gaaactgagg
     1921 tttctaacgg tttttctttg ttttttgtgc caatattgtt tgttttcaaa ggcaaataaa
     1981 ataaaaaaac atccttatcg agtacaatta taaggagcaa aaaaataaaa ctcatcagaa
     2041 aagaggaaga agatatgacg atactatcta gaattttagt gactctagtt gcaattgaat
     2101 ttttttatat catgtatatc gaaacggtga gaactgattc tgacacgaca agtagggttt
     2161 ttaaaatgag taaagaagag ttaagcagaa aatctgttca aacattgttt aagaaccaag
     2221 gagtgtacaa tggactatta ggagtgggac tactttatgg agcttatctt tcttccgcat
     2281 ctaaagaaat cacaagtatg ctattaatat ctattttttt gttgcattat atggcagttt
     2341 gactagcgat cgttggattt tactcaaaca aggtgggcta gctctgttgg cattgctttc
     2401 tattttctta taaatataga aaaaataaga atttatctaa caggaaactt tgtgaaaaat
     2461 attactttat ctcatgaaat atgatattct aatgaatggt attttagaaa atttcatgaa
     2521 aaaggagtta gataggtgtt caaaaattat gtttcctcac taaaaaaaga attttcaggt
     2581 tatgatcttt caagatttca gaaagatctt ttggctggga tcacagtagc tgctgtagca
     2641 ttgcctttag ccttggcttt tggggtatca agcggagctg atgcggccgc aggtttgatt
     2701 acggctatca ttgccggtat cgttattggc ggtttatcag gcggttttta tcaaatatca
     2761 ggtccgacag gtgcgatggc agctatcttg atgtctattg cggcaacaaa gggaatgcaa
     2821 ggtgtattgc ttgctacttt tttagcgggt ctatttttac ttgcagcagg acttttccga
     2881 ttaggaacac tgacttcttt tatcccagca cccgtaatta cggggtttac ttcaggtatt
     2941 gctatcatta ttgcattagg tcagatcgat aatttatttg gtgttcactc ggaaggtaca
     3001 aacgttattg aaaaactaag tagttatcaa acgataggat ttccgataaa cacagcctct
     3061 ttgatcatgg gagggctagt cattttaggg atgtttatct atccaaaaaa atgggcgaaa
     3121 cgaatgccta gttcgctgct ggctatcatt ttggcaacag cagttatgct attgttccat
     3181 ttaccagtag caactgtggg taagattcca caaacattga tcagtagtaa tcgtttgaat
     3241 atgggagatt ttagcttttc tgccttgcaa caagtggcag ttccagctat tagcattgct
     3301 ttattaggaa tgattgaaag cttgctatgt ggtgcttcgg ctggccgaat ggcaaataag
     3361 cccttagata gcaatcaaga attaatggcg caaggaattg gaaatctgtt gcttcctttc
     3421 tttggcggga ttcctgctac tgcggccatc gcccgtacaa gcgtggccat caaatctggt
     3481 gcacaaacta gattagctgg tatgatacat gcagttgtct tactgctctc catgcttgtt
     3541 tttgcgccag tgatgtcaca gattccaatg ccagcacttg caggtgtttt gattgtgacg
     3601 gcttggcgta tgaatgaatg ggaaacgatc aaggagctat ttactaataa atattggtca
     3661 gcagttctat tgtttatcct tacgatgatt tgtacagtta tctttgattt aagtattgct
     3721 atcgtgatcg gggtgatcgg cggctgtgta ttttttgttg tcaaaagcgc tgctatcacg
     3781 atttcattag aaacgatcga ttggcaaaga atggggctgc cagaaacgga aaagctgaat
     3841 aactggacag tagtgtatat tagtggtcca ctgtttttta tgtcttcaga aaaactcaaa
     3901 aataaattgg aagaactaaa tcatcacgat ggtgtcattt tctccatgcg aggcgtacca
     3961 agtattgatt tgacggcacg tgcagttttt gatgaatttc aagaaaaagc agagcaaaga
     4021 ggacaaacga ttatctatac ttccttgcag ccagaagtag aaaaacaact ttctcacttg
     4081 tgggaacata cattcacgca tcaacatcaa acagttgctc atgcgttgac agctttacat
     4141 gcgaaatata ctgcaattag ccattaaaac aatgaaaaag aacagacaag actgtaaact
     4201 gaagatttta tggtcttgtc tgttcttttt aatattgctg taaaagtgaa gctagtactt
     4261 gccagtcttg atggataaca ggtacaaggg agcgattgta gaaaatagct gctggatgaa
     4321 aaagtggaat aattcgatag tttttttctg accattcgta ggcatccttt tgttctgtta
     4381 attgtaagac aggccctgta tagagttgac catgattttt ggtaaccgta tattctttgc
     4441 caagtaaacg ttgaagacca atgtttccaa gtgtcgcaat taattttggc tggaccttca
     4501 tcagttcgta atccaatatt ggtgcatgcg caaatacttc ggaacgagta ggtgtccgat
     4561 ttggataaac agtttctgac tgttgtgtcc gtttattgat ccgatgagtc acgcgatacg
     4621 ggcggctcct tacagcactg gtgatataca cctcttctcg tgttaagcca gttgaagaaa
     4681 gtgcctgcat caattctttt ccagcttgac cgctaaaagg aacatgcgta tcaatctctg
     4741 ttttccctgg ggcttctccc acgagcatca gtttaggatg aagaggtcct tgcccagcga
     4801 taaatccttc tacaggacgg ccgttcattc ttaaagaagc ttcttgtatc agttcttttg
     4861 ggtattccat ttatgctcct cctttttctt ttattataag aataaaagaa acacaatgcg
     4921 actattttat ttggtagaac tgtgaggata gaaaagcaga agtattgctt gaatttttgt
     4981 tttacttttt gattttaaat ttagttgact aacggttgct gttctggtaa gctagtactg
     5041 ttgtaattgt ggactccaca gctacaaccg ctcagaacaa gtaataagca cagcatatgc
     5101 tgtcacttcg gatggcgagt ctaagtatat cagaaggagg tgctttatag catgtacgca
     5161 attattaaaa ctggtggtaa acaagtaaaa gttgaagtgg gacaagcaat ctatgttgaa
     5221 aaacttgacg ttgaagcagg agaaaaagtt gtttttgacg aagttatctt agtaggcgga
     5281 gaatctacaa aagtaggcgc tccaactgtt gcaggtgcaa ctgttgaagg tactgttgaa
     5341 aaacacggca aacaaaagaa agtcgttact ttcaaataca aacctaaaaa acattcacac
     5401 cgtaaacaag gtcatcgtca accatataca aaagtggtta tcgacgcgat caacgcttaa
     5461 tagcgtttga gaaagaaggc ctatatatga tcaaaggaac atttaagcga aatgacgcag
     5521 gtcagatcgt ttcattcact ttgaccgggc atgctgatgc tggtccttat ggaagtgata
     5581 tcgtttgtgc gggtgtttct gcgttagcga tcagcactgt caacgggatt gcctcattag
     5641 ccggttttga gccgattgtt gaaatgaatg aagaagaagg cggttatctt tataccgaag
     5701 tcacttcagg aatgacacaa gaacaaaaca atattgctga gattctatta gaaaatcttt
     5761 tattaggatt acaatcgata gaagctgaaa actcagaata tatccaaatt aaaacaatta
     5821 atgataaata ggaggtgcag accatgttgt tatctatgaa tctacaatta tttgcccaca
     5881 aaaaaggtgg cggttctaca tctaacggcc gtgactcaga atcaaaacgt ctaggtgcta
     5941 aacgtgctga tggacaaaca gttacaggtg gatcaattct ttaccgtcaa cgcggtacaa
     6001 aaatctatcc aggtgtaaac gtgggtatcg gtggagacga cactttattt gcaaaagttg
     6061 atggcgtagt acgtttcgaa cgtaaaggcc gtaacaaaaa acaagtgtct gtttatccag
     6121 tagctcaaga agcttaattg aatcttatga ttaaagaggt tgtgacaaga cttttgtcac
     6181 agcctttttt gtttataaaa ataaaagttg tagtggaggc tacgaagttt actttgtctt
     6241 tttacactta atattttttt gccaatttgg aatcaggatg ttttgataac tatcgttttc
     6301 aattgatgga agctatattg tttgctatca gtgaaataat tatatggtaa acagtgttct
     6361 ttttcttgtt tccattataa aaatcgtatc gggatttttc gttcttttaa attgaacatt
     6421 tctatctatc cgcgtgttat caacaaaaca aaatcaggta aatagttgac gaaacagaaa
     6481 taaatacata gtattatgtt ttgaagccta agtacaatag tctatagaaa aggagcgata
     6541 ccattggcaa aacgcattga ccgaatttat atgtatgtca aagaaaaaac cgctcattta
     6601 acaaaggcag aatatgatca aggagtaaca acacaggaaa ttgctgaagt gttagggatt
     6661 cagcgaacaa atagcagtaa agatctgaat cagctagtgc gcgaaggaaa actgataaag
     6721 acagacggac gaccagtacg ttacatatat caaacactcg ttacgcacgt aaagccagtt
     6781 acaaaacatg tagtcagtta caaagaaacg ccggtctctg aagaaaaaaa tacactccaa
     6841 atagatacta aggatatctt tgcaaaaatc attggagcta acggcagcat gaaaaattca
     6901 gtggaacagg caaaagctgc gattttgtat ccgccaagag gattaaattg tttgattaca
     6961 ggacctaccg gatcaggaaa gacttatttt gcacacgcga tgtatcattt tgcaaaagcg
     7021 catcatgtaa tagatgagga aacggaactg attgttttca attgtgctga ttatgccaat
     7081 aaccctgagc ttttgatgag tcatttattt gggtacgcaa aaggtgcttt tacaggcgca
     7141 gatgaagaaa aaatggggat tatcgatcaa gcggatggcg gtatgctgtt tttggatgag
     7201 attcaccggt tgccgcctga aggtcaagaa atgatctttt actttatgga tcatggaact
     7261 tacagtcgtc ttggggaaac aacgaaatcc catgaagcaa atgtacggat cgtaggtgcg
     7321 accacagaag acccaggttc ttctctatta gaaacttttg ttcggcgtat cccaatcaat
     7381 atcaaacttc cggcttttga aaaacgtcct gcaaatgaga aagtcgattt agtaaaaatc
     7441 atgattgccc acgaagcaaa ccgcacgcag cgaaagattt ctttgacaga agatgtagca
     7501 aaagcattga tcggcagtgt gacctatgga aatataggac aattgaagtc aaatatccag
     7561 ttagtatgtg cacgaggatt tctaaatcat atgcaatcac ccgaaatctc gatcacaatc
     7621 gatgatttga cagaagggat tcgtagcgga ttgattcaat tagcaagcaa ccgcagtgca
     7681 atggcagagc tttctaaaat attggagcca aagataactg tagcaccaaa tgatacgatc
     7741 atgaaaatcc aatcggactc ctatgagtta ccttataatc tatatgatat catcggagat
     7801 aaagcagctt tactgaagtc ggatggtttg gatcaagaag caatcaatca tttcatttct
     7861 acagatatca acatccatct gaagtctttc tataaagacc atggtttttc ttttaatgca
     7921 gacagcaaat tagcagaatt tgtagatccg aaaatcatag aagtgaccaa tcagatttat
     7981 gtaatggtca aaagatcttt accatatgag tttcagcaaa actttattta tgctatgagc
     8041 ttgcatatca gttctttttt gaaaaaaatc aacttaggag aagaacggca tacgaatgat
     8101 aacatccgtg agatggcttt tgattttcca gatgaatatg ctgttgcgaa agaagtgcgt
     8161 agttatatcg aaacgtattt tcaagtggag attccagaaa gtgaagacta ttacttgacc
     8221 gttctactcg tctcgttacg ggcaaatcaa gcaagcggca gaatcggtgt agtcgttgca
     8281 gctcacggaa acagcacagc aagcagtatg gtccaagttg tccaacagtt gttagatgca
     8341 gagaacgtac gagcagtaga catgcctttg gatatggatc cgaaaacagc attggaccga
     8401 attgaacgca atgtacaaga agtagatgaa ggaagcgggg tcatactctt agtagatatg
     8461 gggtcccttg cgtcgtttaa ttcgcaaatt caaagagaca ctggaattcc agtacgtact
     8521 gttgatatgg taacaacttc tctagttttg gaaactgtac gaaaggtctc agtattaggg
     8581 acagatctag atatgttgca tgaatcattg aaaaattttc gaggttacgc agaaatatct
     8641 tctgtagaat ctgttcagga agcaaaacct attcataaga aaaaagctgt tttggctatc
     8701 tgcgcatctg gcgaaggtac agcacaaaga atcaaagaat tgatcgaacg agcggtaaac
     8761 aagcgtcaag aaacagaatt agaagttcta gctttgtcga ttgtggaagt gaaagaagaa
     8821 ctgccagtta tccaaaaaga atatcagatc atagctacta ctgggattac tgatttgaat
     8881 atccaagccc catttattcc tttagaacgt tttattgatc aaaatatcga agtcattttg
     8941 gatcagttgc tgatggaatc agaattggag gaaactgaat tcatctccct agatgaagag
     9001 tcagctaaaa atacgtgtgt tgagtttatc tctgataact tcatctttat taatggtagt
     9061 aagttaatcg atccaatgtg gcaattttct acacaaatct ctcagacgac gggaatcggc
     9121 gatgaagaat atggattcaa aatcaaccta gtgatgcaca cagcaggaat gatcgaacgt
     9181 attattcgga atgaaccatt gactgtggaa gaaaacgaat tgacaaatac aacgaatgat
     9241 cctctttata gccaattggc agcctcagtt gttctgttgg aagatcagat aaaagtaaaa
     9301 gtgccgatag aagaaatgta ttatctgcta cgtctagtcc ataatcagtt agataaaaaa
     9361 gaatacactg tgccatgaat acacaaaaac gatacacttt tatagtgtat cgtttttgtg
     9421 tattggttaa gaatccttta aattcaatta gtgtatcgta aaaaagttgg cacgcttttt
     9481 gcttatagta gtgtgtgcta ggaggtggtt gttcacacag aaatgatagg ggtttctgtg
     9541 aagtagtgag gaagaaggag ttttgcagat ggatattcga ttggcacgta tagatgatcg
     9601 tttaatccac gggcaagtcg caacagtttg gtcgaagcaa acaggtgttg aacgtatcat
     9661 tgtgatcagc gatgtagtcg ctcaagataa attgagaaag tttctactaa aagaagctgc
     9721 accgccgggg atcacagcaa atgtaataac cgtgcagaaa atgattcaaa tctatcatag
     9781 tggattatta tcacgagcaa aagtgatgct tttattcacc aatccccaag atgttgaagc
     9841 ggttgtccgc tgcggtgtac agttgaagtc gttgaatatc ggcggtatga gttttactga
     9901 aggcaaatca atgattacca attttgtttc agtaaatcaa caagatattg attcctttcg
     9961 ttacttgaac agtcaagaag tggagttaga gattcgaaaa gtacctgctg acaggaaaat
    10021 ccttttgatg gaactactag cgaaaatcaa aaaggtgtag caagaatggt tgttggaaaa
    10081 ggtcaaataa ttctgttgta atggttagca attattaata tttttgaatt tgttacaaca
    10141 aaagtaaata ggaggtataa atatggtagg gattatccta gcaagtcatg gacaatttgc
    10201 tgaaggaatc ttacaatccg gttcaatgat ctttggcgaa caagaaaacg tcaaagccgt
    10261 gattttgaaa ccaagtgaag gtccagatga cttgagagcc aaattggaag aagcggttgc
    10321 ttcttttgat aatcaagacg aagtgttatt cttagttgat ttatggggcg gaacaccgtt
    10381 caatcaatca aacacattat tcgaagagca caaagataaa tgggcaatcg tcagcggttt
    10441 gaatttacca atgttgattg aagcctacgc atcacgcttt tcaatggaat ctgctcatga
    10501 aattgcagca cacatcattg aaacagcaaa agacggtgta aaagtaaaac cggaagaatt
    10561 agaaccggca gaagcaccga aagcagcagt tgaagacgca caacctaaag gagcacttcc
    10621 agaaggaact gtggtcggag acggaaaaat caaatatgta ttagcacgtg ttgactcacg
    10681 tctgttacat ggacaagttg cgacagcttg gacaaaagca gtgcaaccaa accgtattat
    10741 cgttgtttca gatgcagtat caaaggatga tctgcgtaag agactaatcg aacaagctgc
    10801 tcctccaggt gtaaaagcaa atgttattcc tattagcaaa atgatcgaag tagcaaaaga
    10861 ccctcgtttt ggaaatacca aagcattgct tttatttgaa aatcctgaag acgtattgac
    10921 agctgttgaa ggtggcgtag acatcaaaga attaaatgtt gggtcaatgg cgcattcggt
    10981 cggtaaagtc gttgtaagta aagtattgtc tatgggacaa gaagacgttg aagcgtttga
    11041 gaagcttgaa caaaaaggtg tgaaattcga tgtacgtaaa gtacctaatg attcacgcga
    11101 taacatggat gatattttga aaaaagcaaa agctgaatta gcaaaagcgt aataaataat
    11161 attaaaattt ataggaggct tatcatgtct attatttcaa taattttagt cgtattagtt
    11221 gcctttctag ctggtatgga aggtattctt gatgaatttc aatttcatca accactagtg
    11281 gcatgtacat tgatcggttt agttaccggt aacctcgaag ctggtatcgt acttggcggt
    11341 acgcttcaga tgatcgcttt aggttgggca aatatcggtg ccgctgtagc accagatgct
    11401 gcattagcat cagtagcatc agcaattatt ttagttttag gtggacaagg tgttaaaggt
    11461 gttccttctg cgatcgcgat tgccgttcct ttggctgttg cagggttgtt cttaacaatg
    11521 atcgtacgta caatcgctgt tccaatcgtt catttgatgg atgcggctgc tgaagaagga
    11581 aacatccgta aggttgaaat gtggcacatc attgctgtat gtttacaagg ggttcgtatc
    11641 gcggtcccag cagcagcgtt gctatttatc ccagcacaaa ctgtgcaatc attccttgaa
    11701 tcaatgccag catggttaac agatggtatg gctatcggtg ggggaatggt cgtagctgta
    11761 ggttacgctt tggtaatcaa catgatggct acaaaagaag tatggccatt cttcgttatt
    11821 ggtttcgttg tagctgcaat ttctcaatta acattgattg ctctaggtgc tttaggtgtt
    11881 gcattagctc ttatttactt gaacctttct aaaatgggtg gttcatcaaa taatggaggc
    11941 ggaagcaact ctggtgaccc tttaggcgac attttgaatg actattaatc ttgaaggagg
    12001 aaaataaaat ggcagaagaa aaaatcaaat tatcaaaaaa agatcgttta gctgttgcgt
    12061 ggcgctctac cttcattcaa ggttcatgga actacgaacg tatgcaaaac ggtggctggg
    12121 cattttctat gattccagca atcaaaaaat tatacaaaac aaaagaagaa cgttctgcag
    12181 cattaaaacg tcacttggaa ttctttaata cacacccata cattgcttct ccaattttag
    12241 gggttacatt ggctctggaa gaagaacgtg cgaatggcgc gcctgttgat gatgtagcga
    12301 ttcaaggggt taaagtaggt atgatgggtc ctttagctgg tgttggtgac ccagtgttct
    12361 ggtttacagt acgtccaatg ctaggtgcac taggtgcttc attagctatg ggaggaaata
    12421 tccttggacc aatcatcttc ttcttaggtt ggaacattat tcgttgggca ttcatgtggt
    12481 atacacaaga atttggctac aaagctggtt ctaaaattac tgatgacctt tctggcggat
    12541 tgttacaaga cgtaacaaaa ggtgcttcaa ttttagggat gttcgtatta gctgcccttg
    12601 tacaaagatg ggtatcaatc aaattcttac cagttgtatc aactgtaaaa ttagataaag
    12661 gtgcttacat cgaatgggat aaattgcctt caggtggtga aggaatcaag agtgcatttg
    12721 aacaagttaa taatggctta gccctttctc ctgaaaaggt aacaacatta caagacaact
    12781 tagaccaatt gattcctggt ttagctgcat taggattaac attgttatgt atgtggttgc
    12841 ttaagaaaaa ggtttctcca atcgttatca tccttggttt attcgtagtc ggtgttgttg
    12901 gacacgtcat cggactttta taatccataa aaatatagct cgggcgttgt cccgagcttt
    12961 ttttatatag tatactgttc ataaacaaat atctggaggg agaaaatggt tcaatcaatc
    13021 aatacaaaag tagacttggt aattgatgct acttcgttta cgggtctgac agattacggg
    13081 caaatcatga taggtaataa tggttttgag ttttaccatg cgcgagatag acgcaaatat
    13141 atccaaattc catgggaaga agtggattat gtactagcat cagtcatgct aaagggaaaa
    13201 tggattcctc gatatgccat tcaaacgaaa aaaaatggta catacacatt ttcttccaaa
    13261 gaacctaaaa aagtgcttcg tgcgatcaga gaatatgtag atgaagatag aatggtacaa
    13321 tcattgagtt tctttgatgt agtgaaacgt ggtattcgta gtatgtttaa acgcaagtaa
    13381 aaaataaaga aaacttctaa gaggaggttt tctttatttt tttactttgc agaagaaaat
    13441 atgaaatagc aaaaccaatt atttgtcccc tttaaatccc atatgctaaa attgattagc
    13501 aaagaaggag gttatattat gagttggtta tggacattga ttgttggagc cgtgatcgga
    13561 gcaattgcag gtgcgatcac cagtaaagga aattcgatgg gctgtgtaac gaatatcatt
    13621 gctggactag tcggttcaag tattggacaa gcgattttcg gcgaatgggg accaaaagct
    13681 gcaggtatgg cacttattcc atctatttta ggcgcagtga ttttggtagc agttgtctca
    13741 tttttctttg gaaaacgatc ataagttttt acaaaatagt aaactaaaag gagttgcagc
    13801 gagactgtga ctcctttttg gctttattta tttaaaataa aaagaagttt tccggaaatt
    13861 tttatttaac tgtcgtgtac gaagaaaagt ttgctataat ggaaaaaagc gtgcaaagaa
    13921 agagggagtt tcattatgat gctacgtgta gaaaaattgc gcaaaaaaat gcaagaagaa
    13981 aatttggatt catttttggt taccagtccg tacaatcttc gttacttaac gaactttaca
    14041 ggtacgacag gattagctgt tattactttg gaaaaagcat tttttattac tgattttcgt
    14101 tataccgagc aggcggcagc gcaggctcaa gggtttgaaa ttattaaaaa tgtcggacct
    14161 atttttgatg aggtagcaaa cttagtacgc aaagaagaac tgcactcatt agcttttgag
    14221 gaaacaacag tctcattttt agaatattcg gttttagaag aaatcatcga tgcggaatta
    14281 gtacctgttt cacagatgat cgaagaactc agagaagtga aagatgaaga agaaatcgct
    14341 attatcgaaa aagcatgtca tattgcggat atggcatatg atcacatcct gaaaatgatc
    14401 caaccgggca tgactgagat tgaagtcgca aatcaactag acttttatat gcgttctctt
    14461 ggcgcttcag gtgtttcttt tgatacgatc gttgctagcg gattgcgttc ggctatgccg
    14521 catggtgtag caagcaaaaa aatcatcgaa caaggtgact tgatcacatt ggactttggt
    14581 tgctattacg aagggtacgt ttccgatatg acacgtacat tcgctattgg tgatcctggg
    14641 gaaaaattaa aagaaattta tcaaatagtc ttagatgctc aattagcagt tattgatgct
    14701 gcaaaaccag gaatgactgg tgtccaatta gatgcagttg ctagagatta tatttcaaaa
    14761 catggttacg gggaagcatt tggacattct acaggacatg ggatcggttt agagatccac
    14821 gaaggaccaa acgtttcttc tcgtgcagaa aagcaatttg taccaggaaa tgtgatcact
    14881 gatgaaccag ggatctactt accaggaatc ggtggagtac gtattgagga tgacttgttg
    14941 atcacagaag atggaaatcg tgtgttgact cgttcaccaa aagaattgat catcttatag
    15001 tttcatcaat agaagaagta agcgtaaaaa tcagtgttca cagactttgt tatagaaaat
    15061 cactcgattt aatgatacac tatagaagaa cttttaagct gtaagagata ataaagttgg
    15121 gtgttttctc caattcatag cagtttgcag ctgatcggcg gcagttttct taccacgtga
    15181 tcactatgcc gcatcataga gaattcggat gtatctcgtg cttaggcaaa gggaggaata
    15241 aataaatggc agatgaaaaa aatttgattt taaacgcaaa ccaagattta ggagagatcg
    15301 tgatcgctcc tgaagtcatc gaagtaatta tcgggattgc agcttctaaa gtagaaggcg
    15361 tatacggaat gcgcggaact tttgccagca atgtcactga attattagga cgtgcagctc
    15421 acggaaaagg tgtttactta gcaaacgagg aagatggctt gaaagtagat ctttactgtt
    15481 atctagaata tggtgtttca gttcctaaag tagcaatgga aatgcaggaa cgggtcagcc
    15541 agcaagtcct tttcatgacg gatatcgatt tatctgaagt caatatccat gtagtagctg
    15601 ttgttcctga aaaattagaa caaccaacaa tcgaagaact ttttgaagac gaagaggaag
    15661 agaatgaata aagaattatc aagacacgag attcgggaaa tggcattgca ggctttattt
    15721 ccattagact tcaatgcaga cctaacaaaa gaagatgcga ttttcaacgc aatcgaatta
    15781 gaccaccgcg acatgatcaa cgaagatgaa tcagagtttg ttcctgttta tcttgatacg
    15841 ctagttggcg gtgtctgtgc aaaaaaagat gaattggata aagtgattga aaaacattta
    15901 aaaaacaatt ggcacatcaa tcggatctca aaaatggatt tggtgatctt gcgtatcgcg
    15961 atttttgaaa tgacttatgt gacagatgta ccagcggctg ttgctttaaa tgaagcaatc
    16021 gagttggcaa aaacatttag tgatgaccgt tcacgtaaat tcgtcaacgg tgttttatcc
    16081 aatgtattga aagaattaga agctggggcg taagtcctag cttttttcta tgaatcatca
    16141 taaacctgtt ataaatcggg aaaattctat ggtagaatga aaacacaaaa aatatctggg
    16201 agtggttaga tggcagaatt gattaacgga aaagaattag ctgaaaaaat gcaggcagag
    16261 attgctgaaa aaatccaaaa attgaaagat aatggtatcc atcccggatt agtcgtttta
    16321 ttggtagggg aaaatccagc cagccaaatc tatgtaagaa ataaagaacg tgtagcaaaa
    16381 gaaatcggaa tccattcatt ggtagagcgt tatcctgaga cgatttctga agacgaacta
    16441 cttgcagaaa ttgaaaaata caatcaagat cctagttttc atggtatatt ggtccaatta
    16501 ccattgccaa agcatataga tgaagaaaag atcctgttag ctatccgccc tgaaaaagac
    16561 gtagacggtt ttcatccgat gaatttaggc agactccttg cgggtaaacc ggacaagatt
    16621 ccttgtactc catacggcat catgaaaatg tttgaagctt attctatcga tccggcgggt
    16681 aaacgagcag tagttatcgg acgaagcaat atcgtcggta aaccgatggc tcagctactc
    16741 ttgatggcag atgcaactgt tactgttgct cattctaaaa ccgaaaatct ggctgaactg
    16801 gcacaagaag cagatatttt agtcgtagca ataggacgtg gacattttgt cacaaaagaa
    16861 ttcgtaaaac caggtgctgt agtgatagat gtagggatga atcgtgatgc taacggtaag
    16921 ctgatcggtg atgtgaaatt tgatgaagtg gagcctattg caggctggat cactcctgtg
    16981 ccaaagggtg tagggccaat gactatcacg atgctgatgt atcaaaccgt aaaatctgcc
    17041 gaagcttttg gagcaggtga atagatggca caagaatatt taactgtcac tacattaacg
    17101 aagtatttga aaagaaaatt tgatgccgat ccttatttag aacgcgtata tttaacaggc
    17161 gaaatatcga atttccgttt acgtgccaat gcccatcaat atttcagctt aaaagatgac
    17221 catgcaaaaa tatctgctat tatgttcaaa ggagcattcc aaaaattacg attccagcca
    17281 aaagaaggaa tgaaagtcct tgtcgttggg cgtatttcat tatatgaagc gggaggttct
    17341 tatcaaatct atgtagagca catggagcct gatggaatag gtgctttata tcaagaattg
    17401 gaagaacgaa aagaaaagct gatgaaggaa ggcctttttc aagggcctaa aaaaatgctg
    17461 ccacgtttcc caaagcgaat cgcggtcctt accagtccaa gcggagcggt tatccgcgat
    17521 atcatcacga cggtgaaaag aagatatcca attgtccaat tggttttgtt cccaacagtt
    17581 gtacaaggaa accaagcagc ggacaatgtt gtcaggaata tccagagagt agaagagatg
    17641 ggcaatttcg atacaatgat catcggtcgt gggggtggtt cgattgagga tttatggccg
    17701 tttaatgaag agcgggttgc tcgggcgatt tatcaagcta atacgccggt gatttcatct
    17761 gtaggacatg aaacagatac cacgatcgct gatttagtag cagatgttcg ggctgccact
    17821 ccaacagcag ctgcagaatt agctgttcct gttttgtcag aagagttgat gcgcattcaa
    17881 gaacggcaag ctagattgca gcaggcgttt gtacgccaga tccagcgcaa acaagaacgg
    17941 ttcgagcgtg ctcgacgttc ctatgtattt cggcagcctg aaagattgta tgaaggtcag
    18001 accatcaaat tagaccagtt gaaacagcga ttatatcaag ctacacagca aatttatcat
    18061 gcgaaagaaa aacaaacgat cgcattaagc caccaattgg aacaagtggc tccgctttat
    18121 cgagttaaag cagctcgcca agaaactgct tatctagaaa aacgcttaga agagaaaatc
    18181 caacaatata tgaaacaaca gcagcagcgt tttgctcaag ctgttcaatc tcttgatttg
    18241 ttgagtccat tgaaaatcat gggaagaggc tacagctata cgacgttaaa tgatcaagta
    18301 gtaaaaagtg tcaccgagat tcatcaaggg gatttgctga cgatccatta tcaagatgga
    18361 atcgttaaag gacaagtaca agagatagac aaaggagaat aaaaatatgg aaaatccaac
    18421 ttttgaagag tcactgcaag aattagaaaa aattgtcatg cagttagaac aaggagacgt
    18481 tccattagaa tcagctctag attcgtttaa acgaggaatg gaattaagca aacattgcca
    18541 agatacatta gctaaagcag aagagacctt gacgaaaatg atgacagaat caaatgaaga
    18601 agttgatttt gacggaaacg aggaaagctg agatgagatt aactgacttt tcagctattc
    18661 atctacctgc tgtagaaaaa gaaatcttgt cttttttaga tgagcataca acggatagag
    18721 gactctatga tgcgatgagt tattcagtga aagcaggcgg gaaaagaata cgtcccttat
    18781 tacttttaac ggccgttgct tcctttgatg agcctattga tgttcccgtc tatcaagtag
    18841 cagctgcttt agaaatggtg catacgtatt ccttgatcca cgatgatttg cctgcgatgg
    18901 acaatgatga tcttcgtaga ggaaaaccta ccaatcataa agtattcggc gaagcattag
    18961 ctatattggc cggagatggt ttgcttacag gagcattcca gctaatcagt atggcacact
    19021 taggtaattc tcctaagctt ctgctgcttc agcaattagc tgtttgtgcg ggatcacaag
    19081 gtatggttgc tgggcaagct gcagatatcg agggcgaatc gaaaaagctt tctttagaag
    19141 aattagcatt tattcatgaa agaaagacag ggcatttgat tcgttatgcc ttgctggctg
    19201 gtggcatatt agcgaagcaa cctgaagaaa tcttattgct acttcaacga ttagccgaac
    19261 atttaggttt agcttttcag ataagagatg atctactcga tgtgattggt acaacgaaaa
    19321 cattagggaa aacagctggt aaagatgaac gtatggaaaa aaatacttac ccgcgtttat
    19381 taggcctaga aaagacacgt gaggcgttgg agattgagct gttatccgcc aacaagatca
    19441 tagacaaatt agaagaggac gttttttctt ttgatggcgg gctgatgcgc cagatgatca
    19501 agcaatttga tgtggagaaa tgagggaaag aatggaaaaa gaacgcgtag atgtattagc
    19561 ggtcaaacaa ggattatttg aaacaagaga acaagccaaa cgttcagtga tggctggttt
    19621 gatttacaac gaaaaaaacg agcggtttga taaaccggga gaaaaaattc cagtgagtag
    19681 tgaattaaga gtcaaaggta aaaaacttcc ttatgtttct cgagggggat taaaattaga
    19741 aaaagcactc aaagcatttg atctatctgt tgaaggaaaa acattgttag atattggtgc
    19801 atccactggc ggatttactg atgcagcttt gcaaaatggc gcaaaaatga gttatgcttt
    19861 agacgttggc tacaatcagc tagcttggaa aataagacaa gatcctagag tcgtcgtaat
    19921 ggaaagagtg aattttcgtt atgcaaaacc cgaagacttt accttaggaa ttccagaagt
    19981 tgctgttatc gatgtttctt ttatttcact aaaactgatg ctgcctccat tacatgctat
    20041 tttaaaagaa gagggagaag tgattgcttt aatcaaaccc caattcgaag caggcagaga
    20101 agctgtaggg aaaaacggaa ttgttcgtga ccctcagacc catcaaaaag ttttagaaga
    20161 cattttgtca tttgcggcac aaggtggata tgatgtgctg gaattaagtt attctccgat
    20221 cacgggggga gaaggaaata tcgagttctt ggctcacttg aggaaagtac ccgaaagcgg
    20281 aacaatcaat tcagctatta atatggcaga agtggtttca aatgcacacg aacagtttga
    20341 ccataaataa attgtaactg tgaaaatcaa gtgagaagta tgcggattct tctttattat
    20401 accaaggaaa taagctatca ttgattaaga agaatatgct aaggagcgaa gacgtaatga
    20461 gaaaaaaaga tcggcatcgt ttgattactc gattgttgag tgagcaagat atccgaaagc
    20521 aggaagaatt tgttgaaatc ctgaaaagca aaggaatatc tgttactcaa gctacgattt
    20581 ccagagatat aaaggaactg aaactgatca aggtaccggc ttcagatggc ggctaccgtt
    20641 atagcatacc agctgaaaca aacgaagatg taaatactaa attggaaaaa ctattaaaag
    20701 acgctttcgt ggcagttgac caaatggaaa aatttgttat tttgaaaaca ttgccgggaa
    20761 atgcttcggc agcagcaaat ttgattgata aacgttacaa gaaagaatta ttttcgatta
    20821 tcaatgatga cgataatgtt ttgatgatta cacgaactga agaccaggca gttttattga
    20881 agaaagactt cctgcattac ctttaagttg aggagcgaat gtgatgctac aagaaatcag
    20941 tattactaac tttgcgatta ttccggaatt gcggctttct tttcacgaag gaatgaccgc
    21001 gctgaccgga gagactggtg cgggtaaatc cattattatc gatgctttag gtctgttagc
    21061 aggaggaaga ggttcaagcg attatatacg tcaaggagca gaaaaatgtg tgcttgaagg
    21121 gttgtttgaa ctaccaaaac aagaaggatt ctctgaactg atggttgaat tagggatcga
    21181 aacagatgag gacaatctga ttgttcgacg ggatatgtcc ttaactggaa aaaatgtttg
    21241 tcgagtgaat ggtcatatta tcacattagc taatctgaga agaatcggca gttatttagt
    21301 agatatccaa ggacaaaacg aacatcagga actgctccag cctgaatcac atcttgcttt
    21361 attggatcgt tttggagatg tagctttcca acagaagaaa aagagttatc agcaagaata
    21421 tatctcttat cgtgagctgg aaaaaagggt acgaaaagtg cagcaaaatg aaaaatccta
    21481 tgttcagaga atagatatgc tccatttcca gcaagaagaa atagctgctg ctgatttgca
    21541 agtcggagaa gaagagaaat taaaagaaga aagagaaaaa cttagcaatt atcaaaaaat
    21601 tgctgatgga ttagctgcag gttacggagc actgacgaat aatgaacaaa acagtgtaga
    21661 tggtgttggc ttggccgttt cagaactgca agggatcgcc catctagatg tggagtatga
    21721 agcaatttat gaaaatatcc aaagtgctta ctatttgctg caagatgcaa tcggcgatat
    21781 gagtcgtcag attgatttat tggagttaga tgagagtcgt ttagaagaag ttacgcaacg
    21841 tttagaatta atccgacagt tgaaacgtaa atacggcgaa tccattgagt caatattggc
    21901 ttactatgac gaaatcaccg aagagctagc ttcttctgat ttttcagaag gtcaattgga
    21961 caaaatgaaa gaggaactag agcaaaaaga gcttctactt cagcaacaag ccgcagatct
    22021 tcatgaagcg cgtaaaaaaa tcgcaaaaga attggaaaaa tccattctgc atgaattgaa
    22081 aagtctgtat atggaaaaca ctgagtttga ggtacgtttc ttaaaagaag aaaatagaca
    22141 attgaatcat gatggatttg accaaatcga attttacatt acgaccaatc caggagagcc
    22201 actgaagcct ttggtgaaag tcgcttctgg tggcgaactg tctcggatgt tgcttgcttt
    22261 gaaaactatt ttttcttctg agcaaggtgt gacaagtatt atttttgatg aagtggatac
    22321 aggtgtgagc ggaagagttg cacaggccat cgcagataaa atttctcaaa tatcgaaata
    22381 ctctcaagtt ttgtgcatca ctcatctgcc tcaagttgct gcagtcgccg actatcaata
    22441 ttatattgtg aaagcagtga ttgatggacg tacgcaaact tctgtttcag agttgaaaac
    22501 aaaagaaaga gaagaagaaa ttgcacgtat gctggctgga agtgagatta caaaactcac
    22561 actcgaacat gcaaaagaac tattgaaact cgcaaaaagg acctgagcca cctcgcagtg
    22621 gttcaggtcc ttttcagcag ctgatagcta tattttattt ttacatgaca ctcattacag
    22681 cagtcaatac aacagatcca atcgttaaaa tcagcattgt ccaaatgaca aattttgtta
    22741 ctttagcaaa agtacttgtt tgtttttttt cacgcattgt tttcaacctc gtcattaatt
    22801 agttgattca agtgtacaat cttttttcca tttccacaag agggcttttt tataaaaact
    22861 tccctttttt taaataatag gtagttacga tacaaataaa taatgttaat agaactagcc
    22921 atataaaggc atcatccctt tcagcaatag gtaacttaat gttcattcca tagatactgc
    22981 cgacgattgt cggtatagtt aaaataatcg ttaaagaagt taaaattttc ataatattat
    23041 tcagattatt cgatacgatt gctgaaaaag tctgattcat ttgttctact agttttaatt
    23101 gaatgcgaga agtagtcatt gcctgctctg tttccaccaa tacatcacgt aaatgatttt
    23161 tcaaagcatg attttcttgg aaaagtttat tttgcgctag ttctttcaat gcatctaaat
    23221 tagcagaagt cgcttctctg aaataaacga ggcttttttg gatatccatg atttgataaa
    23281 gttgtttgtt ttcagtggat acttgaagtt tggcttccaa agtatcgcat tgagattgaa
    23341 gcgtagctaa ataactgttg taagagagtg tgacctgcca aatgaattga aagaagatat
    23401 tgagattagg cgaaatatca ctttttggaa aggtctggct aaagactttc tttaaaaaca
    23461 gtggttcatg attcgtaatt gtgataagct tctttttggg cgtcaaaata atagagagcg
    23521 ggtatgtatc cacttgaaaa taaccgctag gacttgtttt agcaaaagga tattgtaaca
    23581 ataataacgc tggctttgtc aactttgatt gattgaattc ttctgtacgg gaattttctg
    23641 catcgtccaa tatggaagtg atgtaatctg acggaatttc aaattgatgt gtcagctgat
    23701 gaatctcttc ttgattagga cgttctacac aataccagat cgtttggtca gtttcctttc
    23761 cggtattacg cagtttctca ttatctaatg taaaatattt gatcatgatt ttcctcctgt
    23821 tgcctgtttc ttttattata acggataggg aattggaata catggaatgt gtttgtaaga
    23881 tatagaatat aactgcataa atttaaataa aatgaaacag ttgtgtaaag tatatacagt
    23941 atacttgaag caacgataaa aaaggagttt acgttcatgg gcacattcac accacttatc
    24001 ttgttttggt atatttaccc ggtaatcgtt ttgtttggtt gccaatttct tgtaaaatta
    24061 ttttcgttaa atcgtcgttt taaaataaaa gcccctgatt tggcgattcc ttttttgtgg
    24121 ggcggtatgc atgcattgtc tagaaataca gggacaattt ctatcttacc gtttttcttt
    24181 atttctgttt tgctaatggg aatttgtatt gctgttttcc aagcatatta ttatgaagaa
    24241 attatttatc cgcgttattt caagatgact tggcgtttgg tttttctgtt gacaatcgtc
    24301 ttgtacgctg tcttgatcat tgtgaacata ctttcttacc tatgaaaaaa atagaaaagc
    24361 tgtaaaaagt cttttaaaag gctttttgca gcttgatttt taaaaaaatg tttatgaata
    24421 aaaaaagttg ttcccggatt tcccagaaaa ggtggtagaa agtgggggat tgtggtagac
    24481 taattttagt tagtggagga atggggggct ttcaatgttg atgggtgaat tccaacataa
    24541 tattgatgca aaaggacgtt taatcgtgcc ctcaaaactt cgtgaagaac ttggcgaaaa
    24601 gtttgttctg acacgcggat tggatggctg tcttttcggc tatccgatga gcgaatggga
    24661 aaatctggaa gctaaactga acgaaatgcc gttggctaaa aaagacgcac gtacttttgt
    24721 gcgattcttc tattcggctg ccactgaatg cgaacttgat aaacaaggac gaatcaatat
    24781 acccagcacg ttaagaaatt atgcagcttt gacaaaaggt tgcgtagtca tcggtgtatc
    24841 taaccgaatt gaaatttggg atgagacacg atggcaagat ttttctgcag cagcagaaga
    24901 gaactttgac gaaattgctg aaagtatgat tgatttcgga ctataagaat aggaagaggc
    24961 tgactaatga ctgaaacatt tcaacactat acagtcatgt tgaaagaaac ggtagatgga
    25021 ttgaacatca aaccggatgg cgtttatgta gactgtacac tcggcggtgc cggacatagt
    25081 gaatatttat taagccaact aagttctaaa gggcatctgt atgcgtttga ccaagatcaa
    25141 aaagcaatcg atcacgccaa gctgcgttta gcttcttatg tcgaacaagg tatggtcaca
    25201 tttatcaaag cgaacttcag agaattagaa gaacgcttga gtgagcatgt agataaggta
    25261 gacggcattt tgtatgatct aggggtttcc tctcctcagc tagatgaagc agaacgtgga
    25321 tttagttatc atcaagatgc accgttggat atgcgcatgg atcagtcagc tcctttatcc
    25381 gcttatcacg taattaatga atattcctac catgaattag taaagatttt cttccgctat
    25441 ggcgaggaga aattttccaa acaaattgct cgtgaaatcg aacgagtacg aaaaacaaaa
    25501 ccaatccaaa caactggtga gcttgtcgaa atcattaaac aagtcatccc agctcccgca
    25561 agaagaaaag gcgggcatcc tgcaaaaaga atttttcaag ctgtgcggat tgcagtaaat
    25621 gacgaactcg gtgccgaaga ggcctcttta gaacaggcaa tccggttatt gaaagtcaat
    25681 ggaagaatca gcgtaatcac attccattca ttggaagaca gaattgtcaa aagtatgttt
    25741 aaagaatata gtacggtaca agatctacca ccgggacttc ctgtcatacc tgacgaattc
    25801 caaccagaac tgaaagtcat tactcgtaaa ccaatccttc cttcagagga agagctaaca
    25861 gaaaacaatc gatcacgcag tgcaaagtta cgtattgcag aaaaaataag aatgaaagag
    25921 gagtagaatg atggcagaat taaagaaaat gcaagattac gaatatgatt tacctgaatt
    25981 ggtggatcag ccggaacaac aaatgcctga ttcttcttcg aatcaagaaa tcattcttcc
    26041 acaatcaccg gcaaaacgat taaagcagat ttctgctttg gaaaaaattg ctgtggcaag
    26101 cgtggcgatt gctattgttg ctttatgtgt tttaacagtt atgctgcgca caaatatcag
    26161 cggagctgaa aaagaaatca cgtcaataca aacagaaatc aatgataaaa agcaagaaaa
    26221 aacgagttta gaacaagaaa aaaacgaact ttctcgtact gaacggatta aacaaatcgc
    26281 agaagaaaaa ggattgtcta ttaatgacga caatttaagg aaagtgaagt aaatgagtct
    26341 taaaaataaa attcggcggt ttatggaaaa gaaaaatcta aatccgatga acaatcgcaa
    26401 aaaagtaggt atcattttat ttgctacgag tattggattg ttctttttat ttgccgtccg
    26461 tttctcgtat atcgttattg gaggtcatgt tgctggtacc tcattagctg aaaaaacaaa
    26521 acagttgtac caaggaagtg aagtagtaaa agcaaaaaga ggaacgattt atgatcgtaa
    26581 cggtgtggcg ctcgcagaag atgcctcctc ttattcaatt aaagcgatac tctcaaaaac
    26641 atatacctct ggggataaaa aactgtatgt tgaagaaaag aattttgata aaatagcaga
    26701 aatcctgcat aagaatcttt ctatagacaa aaaagatgca ctgaatattt tagaggacgg
    26761 cgcaaaaaaa gagctgtatc aagttgaatt tggtagctat gggaaaaata tctcccaaga
    26821 aaccaagcaa aacatcgaag cggacatgaa aaaagaaggt gtcgctggtc tttattttgt
    26881 cgaccatcag gctcggatgt atccaaatgg cgtcttttct tctcatttta ttggatacgc
    26941 agttccagac aaagatgaga atggcttagt tggtaaacta ggtttggagt ctgcttacaa
    27001 tgatatcttg agcggtaaag atggtaagat tatttatcaa aaagataatt ttcaaaatcc
    27061 tctgccaggt acagtggcag aagaagaaaa agctgtcgac ggacaagata tctacacgac
    27121 tttagacagc agactacaaa gttatttaga aacactgatg gatcaagtaa atgaagaata
    27181 tcagccagaa gaattgacag cagtcctgat gaaagcaaaa accggagaaa tcttggcaat
    27241 gggacaacga cctactttca atcctgaaac aatggaagga ttgactggaa aagatgctat
    27301 ctggcgtaat ttcttggtac aagatagtta tgaaccagga tcaaccatga aagttttcac
    27361 tactgcagct gctatcgaag aaggagaatt caacgagaat gaaaccttcc aatctggaaa
    27421 aatccaagta gaagatgcta cgatcaatga ccatgacttt ggtgaaaaag gtgtgctgac
    27481 catgcgtcaa gctctttcat ggtcaagtaa cgtcgggatg gtcatactgg aacagcgatt
    27541 aggcggacga tggtataact atttacaaaa actgggattt ggacaaagta ctcattctgg
    27601 attagatgat gaagtaaacg gtgctttacc tacattaaat attgtcgacc gagcaatgag
    27661 tgcttatgga caagcggtag gtgtgacgaa tttccaaatg atgaaagctt tcacttctat
    27721 tgcgaataac ggtacaatga ttcaacctcg atatatcagc aaagtggtgg atccccaaac
    27781 tggagaagag cgaacaactc aaacagaagt tctagggcaa cctttttcaa aagaaacaac
    27841 agaaaaagtc cgtgaatata tgagagatgt tgtcgaaagc gaaaactacg gtagtgctta
    27901 tggtgtatat agtgtacctg gatacaatgt atcggcaaaa aacggaacag cccaaatcgc
    27961 ttctgataca gggggatatc aaacaggaga tacagcctac ctgtattcga ttgtggagat
    28021 ggttccttct gaagatccag actatgtctt gtatctaaca atgaaacacc ctaagacata
    28081 tgatcgaatg gcattggcta aaatcgcaaa tccattgatg aaacgggcaa tggattttaa
    28141 agaaactgaa gaagattcag atacagaaac aaaaacagaa aaagtatccg tagccgatta
    28201 tcgtaatctt gaagcggacg ttgcagcagc tgatgctcaa aaaagtggac tgcaacctgt
    28261 agtgatcggt aatggtaaaa aagtacaaaa acaatctact gccaacggtg atcagttgat
    28321 ctctggagaa aaactgatcc tatatactgg tggtgataag ctgatgcctg acgtaacagg
    28381 atggtcaaaa gcagatatca tgaagctggg gaaaatcctc ggtattgaag ttagttttga
    28441 tggagatggt tattgtgtca aacaagaact tgctccatat gaaaaaatca ctgaagacaa
    28501 acttagtttt actttagaag aataagaaga gaaataggag agaaaagagc atggaatgga
    28561 cacaagcatt gattcccatt gtcagcagtt gtgcaatgac aattgccgca atgccgctat
    28621 ttattggtta ttttcaaatg aaaaagcaag gtcaggcgat tcgtgaggag ggaccaaagt
    28681 ggcacaatag caaagccgga actcctacaa tgggcggctt agtgtttctg atcggctcta
    28741 ttttgacagg aatttgggtt ggagcttggc aaaaacagct aactcctact cttttcatct
    28801 tgctttttgt attagcgtta tacggagtaa tcggctttct tgatgatttt ataaaaatat
    28861 tcaagaaaag aaacatggga ctgaactcga agcagaaatt gattggacag attctagggg
    28921 gaatcatctt ttatcttgtt taccgttctg aaggttatcc aggtgtattg aatttcttcg
    28981 gactagatct acctttagga atcatttatg gtattttcgc tctcttctgg cttgttggat
    29041 tttcaaatgc agtaaatctg acagatggca tcgatggatt agttgctggc ttaggaagta
    29101 tctcttttgc agcttacggt ctaattgctt ggcatcagca tcagtatgat gtattaatca
    29161 tttgcttaag tgttttagga ggtttactgg gtttcttcgt ctacaacaga aaacctgcca
    29221 agatttttat gggagatgtc ggttcattag cgttgggcgg acttttagcg gcaatttcta
    29281 taatgctaaa ccaagaatgg acattgcttt tgattggttt gatctatgtt atggaaacag
    29341 caagtgtgat gcttcaagtt acttccttta agcttacagg aaaacgaatt tttaaaatgt
    29401 ctccaattca tcatcacttt gaaatgtgcg gatggtcgga gtggaagatt gatacagttt
    29461 tttggttgat cagcattgtg acttcgttga tcacattatg gatcgtttgg taggagatga
    29521 cgggaaatga aaaaaatatc aacatatgaa aataagaaag tgcttgtctt aggactcgca
    29581 aaaagcggag taagtgcggc caaattatta catgaattgg gcgcacttgt caccgttaat
    29641 gatggaaaac cttttgacga aaatccggaa gcacaagagc tgctttcttt agggataaaa
    29701 gtaataacag gtagtcatcc aatcgaattg ttggatgaag aattttcatt gatggtcaaa
    29761 aatccaggga ttccctacag tcatccttta gtagcaaaag cccaagaaat gggtattccg
    29821 gtaattacgg aagttgagct agcttacgaa gtagcggaat gcccaattat tgggattaca
    29881 ggaacgaacg gaaaaacaac gacaacaacg atgacaggac tactactgaa tgcaggagca
    29941 gatcaaggaa ttgcacgttt agcgggtaat attgggtatc cagcaagtgg tgtagcgcaa
    30001 gaagcaaaat cagaagataa aattgtgatg gaattgtcta gcttccaact catgggaatc
    30061 acagatttcc gccctcatat agcggtgatt accaatatct atgaagcaca tattgattat
    30121 catggtacaa gaaaagaata tgtcaaagct aaatggaacc ttcaaaaaaa catgacagaa
    30181 aaagattatc tgatccttaa ctggaatcag tcagaactac aagaattagc gcaaagaaca
    30241 aaagcacgcg tactgccttt ctcgacaaaa gaagtgttgg aagacggtgt gtatgctgac
    30301 gattactcaa tatactataa aaaagaaaaa ataatggaaa tatctgaact tggcgtacca
    30361 ggtaagcata atgtagaaaa tgcactagct gctatttctg tagcaaaatt gtatggtata
    30421 tcaaatgaag ctatacgaga aacgttgcat tttttccatg gcgtaccaca tcgtacgcaa
    30481 tatgtaggag aaatccaagg cagaaaattt tataatgatt caaaagcaac caatatttta
    30541 gcgactaaaa tggctctaag tggatttgaa acgtctaagg tcgtgttatt ggctggcgga
    30601 ttagacagag gaaatacatt tgatgaatta attccttcat taaaaggaat caaagcaatg
    30661 gtcgtatttg gccaaacaaa agaaaagttg atggatgctg gaaaaaaagc aggcatcgag
    30721 acaatagtaa cagccgattc tgtagaacaa gcagttcctt tagcattaga aaacagtaca
    30781 gatggtgatg tagttttatt atcaccagcg aatgccagct gggatcaata cccaaatttt
    30841 gaaactagag gaaacagatt catggaagct gtgaaccgat taaaatagaa aaagtagaag
    30901 cgagcgataa aaaatgaaaa ttttggttac aggcggagga acagggggac atatttatcc
    30961 agctcttgcc tttgtcaatt atgtaaagac tcaagaaccg aatgctgaat tcatgtatgt
    31021 gggagcaaaa cgaggtctag aaaacaaaat cgtccctgat acaggaatgc ctttccatac
    31081 cttggagatt caaggattta aacgaaaaat ttccatgcat aacatcaaga cggtccgatt
    31141 gtttcttaag agtatccgtc aagcaaaaaa aatcctcagt gattttcaac cagatatcgt
    31201 tatcggtact ggaggatatg tttccggagc ggtagtgtac gctgcagcca aaatgggtat
    31261 tccaacagtt atccatgaac aaaacagtgt accaggtgtt accaataaat ttttaagccg
    31321 atatgtggat cggatcgctc tttcatttaa agatgcggct tccttttttc ctgaaaacaa
    31381 agcagttctt gtaggtaatc ctcgagcaca agaagtagca gatactaaaa aatcagatat
    31441 tttgaaaaca tttgatttgg atccagaaaa gaaaacagtc ttgatttttg gcggtagtca
    31501 aggagcactt aaaatcaatc aagcagtatc agttttttta agtgaatata ttccttcttc
    31561 ttaccaagtt ttgtatgctt caggagatag atattatgaa gagatcctaa ataaaataaa
    31621 tcctgaaata caaaatatta gtgtccagcc ttatatcaaa aatatggcag aggtcatggc
    31681 ttccagtgat ctgctggtgg ggcgtgctgg tgcaacttcg atcgcagaat tcacagctct
    31741 ggggttaccg gcagtgttgg ttcccagccc atatgttacg aatgatcatc agactaaaaa
    31801 tgcaatgagt cttgttcacg caggagcagc aaaaatgatt gcagataatg aactaacagg
    31861 tgaatcacta agtcagacag tcaacgaaat catgggtgat gaagaattgc aaaagcaaat
    31921 gtgccgagct tctaaagaac aaggaatccc tgatgcttca aaacgtcttt atgacttagt
    31981 aaaacaaata atcaaaaaat aaaggcggtg gtcttagtga gtaagaaaaa agaaccaaaa
    32041 aaattgtctc atccgtcttc tgatgaaaac aatttgactc cttggcaaaa ggctaaccga
    32101 aaatatctgg cagaacaaga gatgaaaaac caagagccaa aaaaagaaga cataacatta
    32161 gatacacccc tttcagattc tgaagaagaa aaaacggttc aagaggaaca gcaagaagaa
    32221 agccagtccg agaaaaaaat cgaatttttt gaagagatca agcaaaagaa aaacggtgga
    32281 ccatataacg gttctttttt gaaccggctg cccaatttaa aaagtcaacg gcacaaagta
    32341 ctatttcgtc ggttagcttt gatcatcact gtattgggta taccgctgat ttttttgatc
    32401 tattatgttt ctccttatag caaattacaa gcagttgcag tatcaggcaa taagacagtc
    32461 aacagccaag aaatcatctc tgatacaaaa ttgtcattag gagaaaatgt ttggggacag
    32521 tattttcatc gatctactta tatcgatcgc cttaaaaaag cacagccaag aatcgaaaca
    32581 gcaaatatac atttcaaagg gatgaatgaa ttcgatttgg atgtaacaga atataaagag
    32641 attgctttga tcgcaaaaaa caatcaatac tacccagtga ttgaaaatgg aacagtatta
    32701 gatgaaaaag tagcaaatcc tacaaaaaat ctccctatct tggaagagtt caaagactct
    32761 gcaaaaatca aagaattaac aaagcaatac aatcagttat catcagaatt acaaaaagca
    32821 atttctgaaa tcaagtacac gccaagagca agcaataaaa atctgatcca attgaatatg
    32881 aatgacggca atcaagttat tgtaaatatc aataatcttg cgaaccaaat gaaatattat
    32941 tcgcaagtag ccaaagatat ggatgaaaaa ggtgtgatcg acatggaagt tggtatcttc
    33001 tcgcatcctt acggtagcac tcaagaaacg gaagaatcgg gccaatcgga agaaacaact
    33061 gaaagtgaag aaaatgcgga tcaaacaaac gaatcaagtg aagaggcaga aacgcaaaaa
    33121 gcacaaacac ctggatcgtc tagcacaaac ggatcatctg attcaaatga ttcaagtgaa
    33181 acaagtcaaa tagaagataa tccaagtaca actccgtcaa gtttaaatga aaattgataa
    33241 aacaacttta aaaagtaaga atgtactttc taaaaaccag taatttatgg tagaattgga
    33301 agcagtgaat atatctatta ataagtatat tttaaaacgg acgctagttg ttcgcttgta
    33361 tatggaatag taagtaggag ggaatcccat tcatggcaaa aacaggaatg tatgtaggcc
    33421 ttgatattgg aacgacatct gttaaagttg tcgtggctga atatatcgac agccaaatga
    33481 atattattgg agtaggaaac gcaaaatcag aagggattaa ccgaggcatt atcgttgata
    33541 tcgataaaac ggtccaagcg atacaacgag cagtacgaca agcagaagaa aaagcaggta
    33601 tccagatcaa aggcgtaagt gtcggtttgc cagcaaacat gcttgaagta gaaaattgcc
    33661 agggaatgat tgcagttaac ggagattcaa aggaaatcac cgatgaagat gtcagaaatg
    33721 tggcttcagc tgcccttgtt cgttcaatac ctcctgaacg tcaaatcgtg tcaatattgc
    33781 cacaagattt tactgtcgat gggttcgagg gaatcaaaga tcctcgtgga atgatcggcg
    33841 taagattaga aatgtacggt ctgttgttta caggacctaa aacgatcatc cataacatac
    33901 gtaaatgcgt ggaaaatgcc ggattaatcg tcaacgaaat ggtgattact cctttagcgc
    33961 tgactgaatc aattctttct gacggagaaa aagattttgg tacgatcgtc attgatatgg
    34021 gtggcggcca aacaacaacg gctgttatgc atgataagca attgaagttt accaatcttg
    34081 accaagaagg tggcgaattt gtcactaaag atatctctat tgtattaaat acgtcattta
    34141 acaatgcaga agcgttgaaa ataaactacg gggatgcata cccagaacgg acatcaccag
    34201 atgaagaatt tccagtagat gtgattggtc agtcagaacc agtgaaagtc gatgaacgct
    34261 acttgtcaga aattatttca gctcgaatgg aacagatttt caacaaagca aaagatgcat
    34321 tggaccaaat cgaagcatta gagttgccag gtggcgtcgt attgacaggc ggagctgcta
    34381 gtcttcctgg tgttgtggac ttggcacaag aaatcttcgg cgtaaatgta aaattgtatg
    34441 ttccaaatca catggggctg agaaacccgg tatttacaaa tgtaataagt atcgtggatt
    34501 attcagcaaa cttgagtgaa gtgtatcaat tggcaaaaat tgctgttacg ggtgaaacct
    34561 cagcagctcg tcaaatggta gttgaacaag aaacaacaaa cacatatgag agctatgaag
    34621 cacctgaaga aacaatctac gatgagccgg aaccaaaaga gtccggagaa aatgtaaaaa
    34681 ataaaatcaa gggtttcttt acaaatattt ttgattaatt catcctggga ggaataagat
    34741 atggaattct caattgataa taatatcaat gacggcgcag taatcaaagt catcggagtc
    34801 ggtggtggcg gtggaaatgc tgtaaaccga atgattgaag aaaacgttaa aggtgttgaa
    34861 ttcattacag ccaacacaga cgtgcaagca ttaaaaaatt caaaagctga aacagttatc
    34921 caattaggcc ccaaatatac tcgtggttta ggtgctggtt ctcagccaga agttggacaa
    34981 aaagcggcag aagaaagtga acaatcctta cgcgaagctt tagacggtgc agatatgatt
    35041 ttcatcactg caggaatggg tggaggaacc ggtacaggtg ctgcaccaat cgttgcaggt
    35101 atcgcgaaag aattgggcgc attgactgtt ggtgtcgtga cacgtccatt cacttttgaa
    35161 ggaccgaaac gtggccgttt tgctgcagaa ggtatcgctc gtttgaaaga aaatgtggat
    35221 acattattaa ttatctcaaa taaccgttta ttagaagttg tagataaaaa gacaccgatg
    35281 cttgaagctt tccgtgaagc agataatgtt ttacgacaag gtgtacaagg tatctctgat
    35341 ttgatcacag cgccaggtta cgttaacctt gactttgctg acgtgaaaac agtgatggaa
    35401 aaccaaggta cagcattgat ggggatcggt gtggctagtg gagaagatcg cgtagtagaa
    35461 gcaacgaaaa aagcaatctc ctctccattg cttgaaacat ctattgatgg agctgaacaa
    35521 gtacttctta acatcacagg cggtttggat atgacattgt tcgaagcaca agatgcttca
    35581 gatatcgtag caaatgcagc aactggcgat gtaaatatca ttctaggtac atctatcaat
    35641 gaagaaatgg gcgatgaaat ccgtgtgacg gtcatcgcaa caggtatcga tgaatcaaaa
    35701 aaggaacgca agtctagccg accagctaga caagcacaaa tgcaatcacc tgctcaaaag
    35761 actgtattag atatggatca agctaaacca acttcttcag aagaagaaaa cagttttggc
    35821 gattgggata tcagacgtga acaaaatgtt cgtcctagag ttgatgattc caattttgac
    35881 aatatcgaaa aaaaagaatt tgatacattc aaccgcgaag aaacaaaatc tcatggcgat
    35941 gatgaattaa atacgccacc gtttttccgt cgtaaaaaat aaaggagagg aagagcacat
    36001 gattgctgac aacttgcaga aaatcaagca agaaattcag gattcgtgtg ctcttgttca
    36061 tcgtgatccg aaagaagtta cattagtagc tgtaacaaaa tctgttgaat ccgctcaagc
    36121 tgaagaattg gttagagctg gcgttatgaa ttgtgcagaa aaccgagtag ataaattatt
    36181 agaaaagaaa caagatttat ttgattttcc tgaaataaag tggcatttaa ttggtaattt
    36241 acagcgcaga aaggtaaaat tgattgtaaa tgaaattgat tactttcatg cgttggacag
    36301 tttaagatta gcagaagaaa tccagaagcg gttagagaaa gaattatcct gttttattga
    36361 agtaaatgtt tctggtgagg aatcaaaaca tggaatttca ccagatgagc ttttaccgtt
    36421 tgtggaatct ttagctgcct gcacaaaaat caaggttgtt gggttgatga ctatggcgcc
    36481 taaagaagct tctgatgagc aaatccataa agtgtttggt acgctgaaag aattgcgtga
    36541 tcttgttcaa gcaaaaggtt atgcccatgc accatgtagt gaattaagta tggggatgag
    36601 tcaagacttt caaattgcga ttgaagaagg tgcaacattt atccgtgtag gaacagcgct
    36661 attcaaagac gaataaagga ggaacaaaaa tgccgctttt aaacagagga gcaattgcta
    36721 attttttcgg attagctgat gaggaagagt acgaatacca agattatcct gaaacaacaa
    36781 aaaaggctgt acagccaact aaaaaaaata caacacagaa tcaatcaact cattctgtat
    36841 ctgctgcgaa tactcatgaa aaacaaaaaa cggcgacttc acgtcctgta acgcatgaaa
    36901 gtattcagcc ggctgaaaag aaaaaagtaa ttgaactaca tcaatcacct acaaaaactg
    36961 tagcgaaaga aagaacagct tcaagaacct ctacacaacc taaagcaaat cttgctggaa
    37021 aaatcactgt aatggaacca agagcttatt ctgaagctat ggcgattgct aaacgaatca
    37081 ttgctggaga agcaacctta gtgaattttc atttagtaga agaaaaacaa gcgagaagaa
    37141 tcgttgattt tctaacagga acagtttatg cactagatgg agatatcaaa cgtgttggag
    37201 atgagatttt tctttgtaca ccgactggga tggagattga cagttcaacc gctcaatctt
    37261 ttgcagatgc gaatttgttt gatctgtaag aggaggaact acgatttata ctattgcact
    37321 attacttcat ttacttcaac gggcagccta tttctatagc attatcttga tggtatatgc
    37381 attgctctct tggtttccag gcgggtatca atcagggcta ggacgattat tagctaagat
    37441 ctgcgaaccg tatatcagtt tgttcgatcg tctgcctttg aggattggac ccttggattt
    37501 cacaatttta ggggcaatcc tgatcttgaa cttagccgta caaggtttag cacagatcgt
    37561 tatatggata actgtccatt tagtttattg attgaagcaa caaaatcttt attctcagaa
    37621 tagataggag gggaaaattt tggatgcaaa tgtataccag cactttcggg cagatgaacg
    37681 tacatttatc gattcggtag gcgattggat tgaacaggtt caaggacaat atgcacccta
    37741 tctgaccgaa tttcttgacc caagacaatc ctatatttta gaaacactga ttcgacaaag
    37801 cagtgatttg cgtttcatgt tttatggcgg atatgaacag gcagaaagaa aaagatgttt
    37861 gattttcccc gattattacg aacctgtaga ggaagatttt gaaacagcat tgtatgaaat
    37921 ccattatcct agcaaatttg ccagcctaag tcatgggaaa atccttggaa ctttagtggg
    37981 aacggggatc aaacgctctt actttggcga tatcatctcg gacggtgatc gctggcaagt
    38041 atttattgca aatgaggtgg atcattttgt tgctgcacaa gtaacaaaga ttggaaaggt
    38101 tgctgtacgc ttggaaccaa tcaaatacac agaaatgatt atgccgaaag atagctggac
    38161 acaagaaaga ggaacagtta gttccatgcg actagacagt gtgatctctg agatttataa
    38221 tatttccaga cagcggtcca agcagctgat cgaagctggt aaagtaaaag tgaactggac
    38281 agaaaataca agacctgatt ttgtacttga actattagat attatttcag tcagaggtta
    38341 tggcagagtc cagatccaag aacttgaggg gaagacgaaa aaagaaaagt acagggtact
    38401 gttcggtgta ttacgtaaat aaaataaaaa ggtggtttac tcatggcttt aactccatta
    38461 gatatccaaa ataagacatt cccgacaaaa atgcggggat ataatcaaga cgaagtagat
    38521 gatttcttag atttagttgt tcgtgactat gaggaattga ctcaaagaaa tcgagaatta
    38581 gaaaaagcag tcaaacattc tgaagaaaaa cttgagtact tcaatgaatt aaaagatgct
    38641 ttgaaccaat caatcatcgt agctcaagat acggctgata aagtaaaaac aagtgcaagc
    38701 aaggaatccg aagtgatcgt tacttctgca caaaacaaag cagatgagtt agttgcgaac
    38761 gctgaaaaac gtgcacatca attaacaact gatgcagaag aaaaagcaag aaaaatcttg
    38821 acagatgcaa cagaaaaagc aagacagctt gcgacagaaa ctgaagatct taagaaaaaa
    38881 acacgagtat tccatcaacg tatcagcttg atgcttgagt ctcaattaga acaagtgaaa
    38941 agtccggaat gggatgaaat tttacaacca ttctccagct acgtgactga cagccatgaa
    39001 gtgatcaaag aagttttagc aaaacagctt gacaatgaaa atgatactga tgtaaactca
    39061 gacacaggag tcatagaagc acctatgacg gcatttgata cacaggctat tgatatctcg
    39121 atcgtgcctg gtgaaaatga aaacgagtag aacagaaaag cactttgtta ttcttaaagc
    39181 gagccgatga gagtggaagt tcggtaagac actgcatggt gaaagatcct ctacttgaga
    39241 cctgcttttc cgaaattaga gtaagaagca gcggctgacc tcgttattgg tcacagagag
    39301 tttgcactag atagatgcaa ctaaatttgg gtggtaccac ggcatgttcg tcccttgcgg
    39361 ctgaacatgc ttttttgtgt ccggaaaaca aataaaggag tgtatggttg aatgaaaatg
    39421 aaagaaacct tgcaattagg aaaaacaaaa ttccctatgc gtggtaattt gccaaaccga
    39481 gaaggcgagt ggcaaaaaga atgggaagaa aatcgaatct accaaaaaag acaagagttg
    39541 aacgaaggaa aacctagctt tgttcttcat gatggacctc catatgccaa tggtaatatc
    39601 catttaggac attcattgaa taaaatcagt aaagacatta tcattcgttc aaaatcaatg
    39661 tctggctatc gtgcaccata tgttccagga tgggatacac atggattgcc gattgaacaa
    39721 gtattggcta ataaaggcgt gaaacgtaaa gaaatgtcca tggcagaata cttggaaaaa
    39781 tgtcgtgaat atgcactttc ccaagtagat aagcaacgag cagatttcaa acgcctagga
    39841 gttgcaggag attgggaaca tccttatgtt acattagatc cttcttatga agctgcacaa
    39901 gtacgcgtat ttggtaaaat ggctgaaaaa ggctatattt acaaaggatt gaaaccaatt
    39961 tactggtctc cgtcaagtga gtcttcttta gcggaagctg aaattgaata taaagatgta
    40021 aaatctccat ctatttttgt agctttcaat gtcaaagacg gcaaagatat tcttgatgaa
    40081 gatacagctt ttgtcatttg gacgacaaca ccatggacat tgccagcaaa ccaaggtatt
    40141 gctgtaaatc caaaatttac gtatgtattg gtggaagccg atggccgtaa gtttgtcgta
    40201 gcgaaagatt tgctagaaac agtccaatca gaaatcggtt gggaaaatgt aacagttcta
    40261 aaagaatttg ctggacaaga aatggaatat atgactgcaa gtcatccatt ctatgaacgt
    40321 gaatcacttg tgattttagg cgatcatgtt actttagacg ctggtactgg attagtccat
    40381 actgctccag gacatgggga agatgactat atcgctggta gcaaatataa actatctgta
    40441 gtgtcacctg tagactcaaa aggattgttt acagaagaag cacctggatt tgaaggtatc
    40501 ttttatgaca aagcaaatcc tatgatcact gatctattaa aagaaaaagg agctttgctg
    40561 aagctagatt tctttactca tagttatcct cacgattggc ggacgaaaaa gcctgtgatc
    40621 tatcgggcaa ctccacaatg gtttgcatct atcgataaat tccgtcagaa tattttggat
    40681 gaagtagaaa aagtagagtg ggttatccca tggggtaaaa cacgtttgta taatatgatc
    40741 cgtgaccgcg gcgattgggt aatttcccgt cagcgtgcat ggggagtacc acttccgatt
    40801 ttctatgctg aaaatggaga agcaatcatc acaccagaaa caatcgaaca tgtggcaaaa
    40861 ttatttgctg aacatggatc aattatctgg tttgaaaaag aagcgaaaga acttcttcct
    40921 gaaggattta cccacccagg ttctcctaat ggcgaattta caaaagaaaa agatatcatg
    40981 gatgtctggt ttgattctgg ttcttctcat gaagctgttt tacgtcagcg accagaatta
    41041 tcattcccag cagatatgta tttagaagga tcagaccaat atcgtggctg gttcaactca
    41101 agtatcacga ctagtgtggc tatcaatggt gtagcaccat acaaatcagt tatttctcaa
    41161 ggatttgctt tagatggtga aggccgtaag atgagtaaat ctttaggaaa catcattgca
    41221 ccagaaaaag tgatcaaaca atttggtgca gatatccttc gcttatgggt atctagtgta
    41281 gattatgaag cagatgttcg tgtttctatg gatatcttaa gtcaagtggc agaagtatat
    41341 cgtaaaatca gaaatacgat gcgtttctta ttagcgaata cagaagattt cgatcctaaa
    41401 aaagatactg tttcgtacaa tgatttacgt tctgtagaca aatatatgac cgttcgattg
    41461 aaccaagtaa tcaaagaaat ccgagaagaa gggtacgaca aatataactt catgcatatt
    41521 taccgtacag ttatgaactt cttgacggtt gatctatcgt cattctacct ggattttgct
    41581 aaagatgtag tttatattga agcagaagat gattatcaac gtcgttgcat gcaaactgtt
    41641 ttctatcaaa cagctgtagc tttgacaaaa ttattgactc ctatcattcc gcatacagca
    41701 gaagaaatct ggtcattcct gaaagaagaa gaggagtacg ttcagttaag cgagtttcct
    41761 ggttatgaag agtttgcaaa ccaagaagaa ttgatggata cctggactgc tttcatggac
    41821 ttccgtgata atgtcttaaa agcattggaa gaagcaagaa acagcaaatt gattggtaaa
    41881 tctttggaag caaaactaac tgtttatcca aaacaacaag ttcgtgaaat gttaaaagct
    41941 ttggatgcag atattgcaca attattgatc gtttcaccag actactttga agttatggca
    42001 gcagatgaac aagtgccaga taacgctatg gtatttgatg atgttgctat tacagtggaa
    42061 aaagcagacg gggaaacttg cgatcgctgt cgccaagttc gtaaagatgt aggagtagat
    42121 gaaaaacttc ctcatctatg cggtcgttgt gcaaaaatcg ttgaagactt ctatcctgaa
    42181 gctgtagctg aaggattcga agaaaagtaa aagggaaaag ggggtgtgac atgttctttg
    42241 tcacaccccc ttttgttatc aatcgtttaa ttttccacgt tcacgatacc agttatctgg
    42301 ttgccagatc cattcgaatc cgtctttttc aagtagttcg aaagctgctt taggtcccat
    42361 tgatccagct ttgtagttgg gaaaatccgg ttgtgtttgg tcccaagctt ttcgaatgac
    42421 atccacgata tgccaagatt gagcgacttc ttcccaatga gagaagttcg ttccatcacc
    42481 attcaacgca tctaatagta atttttcgta agcttctggg ctattttcaa ccatttctgc
    42541 actatttcta aattccaatt tgattggttc cgtttcaaat ccttgcccta cttctttccc
    42601 attcaaggat aaagaaaatc cttcagttgg ctgaatatag atcgttagaa cattaggtgg
    42661 aagtgtcgta tcgtcacatg gttcatcgac agatgttttg aatacattaa caggaacttg
    42721 tttgaatacg atgttgatcc gagtcccttt ttcagtcaaa cgtttgcctg tacgtacata
    42781 gaaaggaaca cctgaccaac ggaagttatc gatagtgaat ttgcctgcga cgaatgtttc
    42841 agtctctgat tgagcatcca ctttgtcttc ttcgcgatag cccttgaatt gtacaccatc
    42901 caattcacct tgagcatatt gcccgcgaac gaagttttct aacacttctt cttcgttata
    42961 aatgcggata gctttcaatg ctttgatctt ttctgtacgg atttcttttt cggaaaatgc
    43021 tactggcggt tccattgcaa gtaatgctac aacctgtaaa atatgatttt gcaccatgtc
    43081 tttaagtgcg ccactatgat cgtagtagcc cccgcgatct tctacaccga ggttttcgcc
    43141 aaaagtaatt tggatattgt cgatatagcg attgttccat tgagcctcaa aaatattatt
    43201 ggcaaaacgg atagctgaga tgttttggat catttctttt cctaaataat gatcaatcct
    43261 gaaaatatct tgttctggga atacttctct gatttgctgg ttcaattcaa aagcagactg
    43321 gtaatcagaa ccgaacggtt tttctatgat caaacgattg aagccatttt ttgtcataat
    43381 attttgtgat ttcaaatgag aaacgatcgt tccaaaaaat tgaggtgcca tagccaaata
    43441 atagacacgg ttaccgttta attgatagtg tccatctaat cggtcagaca attcttttaa
    43501 tgtctgataa tgcgttgaat catttacatc atgggattga tagtaaaaat ggcttgcaaa
    43561 ggtagttgct tcttcatctg aaggattcaa tgcacggatt gtttctttga caacttcacg
    43621 gtagtgctca tcgctccagg gacggcgagc ggttccgatt acagcaaaat gctcgcctaa
    43681 atttcctttt ctgtaaaggc ggaacaaaga cgggtacaat ttacgctggg ctaggtcacc
    43741 tgtaccgccg aatatcgtaa acaatacatt tttttcatta gacatgtgga tacactcctt
    43801 tatattttat cgacaaaaat cgtgctggcc gccttaaagc tgacggggat tttctttcta
    43861 tcattttgga tagtgatcgg tccttcataa gctgcgatgt caacgatctc atattcttcg
    43921 ttgatattca ggtcaatagt gactaagtaa tccaacaatt ctttttcatc aagcactcgt
    43981 gcgatacgca cttttgtacc gacaggatag gactccaatg tttgtcggcg ttcttcatgg
    44041 acaacttcct cttttttagg aatcgatcct ccatgaggac aatgttcagg atgattcaaa
    44101 tagttttcta aatgatctgc aagatgttcc gaagtcacat gttccaatac ttcagcatca
    44161 tcatggactt cattccagct atagtctaaa tgttcaacta aaaaaacttc ccataagcga
    44221 tgtttgcgaa tcagactgct agctttttgc agtccgcttg cagtcaattg tacaccttga
    44281 taaggggaat gttctacaag ctcttctttc acaagtttag aaatcatttc actgacagat
    44341 gcagctgaga catctagact agatacgatt tgtttattgt tgactttcgt tgtatctcca
    44401 cctagttcta aaatgatttt caaataatct tctcgatttg gtgtcatatt cgatcatcct
    44461 ttcatggtaa aaaaccatca ttagtaagtg taacaaaaaa aacgttaatt gactattttt
    44521 ctaaataaaa aacaaaggat ttttagacgt ttttacaaca aaaaacgaaa gatgatagag
    44581 aagactcatt ctttcgttta taaaggatat atatatacat tgggagggat ctatttttca
    44641 gataacaact tatatgaagt gtctgcagat tcgtcataaa gagtttgttc gggataagaa
    44701 aagataagat aaaaaccata ctgatcacgt acgactaaac gatattcatc tatttctacc
    44761 acagatgtgc caagagactg accgttgatc aaaaacgtgt aatcagatgt aatctgtaat
    44821 tgttgttttt gctggctatc actaaagaac catgtacctt gatactttga gagtccttct
    44881 gacttttccg cttgtttttt ctttttcaag taaataaaac ttgagagaac ggtaatgagt
    44941 gaaccaagaa aatagatcat tttttttatc accaaatcac tcctttatga gaaaataatc
    45001 gcatagacat attctttctt ctttatttca ttgtaccgaa taaaagctaa aatttctcta
    45061 agactttcga ctggtttttt tactgttttt ctacaaatta tgataggata catagtagga
    45121 agaaaggtga cataatttga agtatcagca agtggaaata gcttttttta ttgaccgccc
    45181 gaatcggttt atagcacatt gtatgaaaaa agacggagaa ataattattg cgcatgtcaa
    45241 aaatacaggt agaggaaaag aggtcctgat accaggcgct gaagtggcta ttgtatttgc
    45301 tcctggacct aaacggaaaa ccgcctatga tctgattgct gtaaaaaaga agggtgactg
    45361 gtttaatatc gatagtcaat tgcctaatcg gctggcaatt gatggtattt tagacggcac
    45421 gatcctttta ccaggattaa ctggtccatt tacggtatac aagcgtgaag taacttatct
    45481 tcactccaaa tttgatattt atttagagac ggtggtcgga caaaaagcat ttgttgaagt
    45541 caaaggtatg acacttgaaa ataaagcgat tggtgctttt cctgatgcgc ccacactcag
    45601 aggattgaaa catataggag aattaacgta tgccgcacaa gatggttatg ccgcttatgt
    45661 cttgtttatt gctcagttcg aacatcttca tctggcaacg atccatgaag aaatgcaacc
    45721 agcactagct gatatggttc gacatgcgca gcaaagcgga gttcaaatcc tcgcctataa
    45781 ttgtcaagta tcggcagatg aggtaactgt caagcaggcc attccatttg atgtagatat
    45841 cccttttgaa gatcctatac aatagaaaga aggtaaaata atgatcaact taggtattat
    45901 cggaacaaat tggattactc atcaatttgt ccaagcagct ttaagcacaa aaaaatatga
    45961 attgacagcg gtatattcta gacatttgga aaaagcacag gaatttggtt ctcattatga
    46021 aggggatatc gaattcgcaa cagatttgaa gacttttttc aatattactc atatggacac
    46081 catttatatt gcttctccga atagtcttca ctttagtcaa gctaagcaag caattttggc
    46141 aggaaaaaat gtgatagttg aaaagccagc tttttcgacg ccaaaagaaa tggatgaaat
    46201 catccatttg gcaaatgaac acaatgtgta tttttttgaa gcagcaagaa atatccatga
    46261 atcaggtttt aaaaagattg ccgattactt accattaaaa gacgagataa tcggtgcaaa
    46321 tttcagctat atgaaatatt cttcgcgcta tgaccaagta ttagatggag aagaaccgaa
    46381 tatcttctcg actcatttct caggtggtgc attgatggat ttaggtgttt accgtgtata
    46441 tgcagctgtt gcttggtttg gaatgccaaa agaagtccat tatttcccaa gaaagatttc
    46501 tactggtgta gatggtcttg gatgggggat cttacgttat gagaattttg atgtatcgat
    46561 ccagccaggt aaaatcggtg attcttattt accgtcagag atttattttg actcaggaac
    46621 gctagtgatg aatggagtca atgcaattga acaagcacaa tttcatgatc gcgcgcataa
    46681 agaaatcatt gatttggcgg taacagctgc agaaaatcca atggcagatg aagcagagga
    46741 ttttgccaat gtcatggctc atccgaaaga tccagcttgg ggattgttgt atgaagagtg
    46801 gatcgagcta gctagaaatg tgaaccaagt gatttatgat ttaagaaaaa atggcggcat
    46861 caaattcgat gcagataatg aggaagattt ttaatgaacg aatttgtaca agtatttccc
    46921 gaaaattggc agaaaaaata tgaggataaa gggtttatct caccttctct tattcaacga
    46981 gcagtttttc agccactaag taataaacaa agtatagtag cggtttctcc tacaggttca
    47041 ggtaaaacac tggcttatct ttggcctcta ctactaaacg tggaaccagg tgaagcaagt
    47101 gcgttggtca tttttgcttc ttctcaagaa ctagctattc aagtagcaga tgttgcacgt
    47161 gaatggggaa aagacaaaga gttgaaagtc caatctttgg tgggcggagc caacgtcaaa
    47221 cgtcagattg agggtttgaa ggaaaaacca gaaatcttga ttggtacacc aggaagaata
    47281 ttggaattga tgaaagcaaa aaaaataaaa gcacatcaag tgaaaacaat ggtatttgat
    47341 gaagcagacc agctatttga cgctgggaac agccaaatca ttgatcaaat tcttcatcaa
    47401 gctccaacag agtatcagct agcttttttt tcagcgacag cagatcgttc ccttgaaagc
    47461 attgaaaaaa tcactgggaa aacgtttgag acaattgacg tgacagcaga ggacgattct
    47521 cgaaaaggac tgagacatta ctttttacgt gtaccgatac gaaagaaaga tgactacttg
    47581 agacgtctca cgcatataga agattttcat ggtctgattt tctttaatca actgactgaa
    47641 ttaggcgtaa tggaagaaaa attgctgtat agaggtgtac cggtaggaag tctggcctct
    47701 gatcagaaca agctactccg aaaagcagcg ctagaacaat tcaaaaagaa aatggtcaga
    47761 gcacttttga ccacagatgt ggcggctaga ggtttagata ttacaggtct tccttatgta
    47821 gtgaatgcag aagttccgtt aagtgaagaa gcttatttgc atcgttcggg aagaactggt
    47881 cgaatgggta atgaaggaat agtaattaca ctcgtacaag ataataatct aagagattta
    47941 aaacggcttt tacgtccatc aaatataaca cttgaagaga tttttttata cggaggtaag
    48001 ctgcaaactg agcagccaac caaagaagat gcagctcctg cagtaaataa aaagtatgcg
    48061 aaaacttttt ctggaaagga gcagaaccca gaatataaca aagaaaaaat aagaaaaaaa
    48121 gttaaaaata aatcaaaaaa agagagaaat aaaggagcaa ggcgcaaata agcgcctttt
    48181 tatgctatga ttatgaaaac gggaacaaaa ttggttgcca gaggaggggt tatgtgaaag
    48241 aacgtcaaga agagatcttg cagctattga cagaaaacca acaaggattg acagcaagtg
    48301 atgtagctga gcgcttaact atcgatcgaa gcaatgcaag ccgatattta agtgaactat
    48361 acaaggccca tcatattgta aaaaccgctg gccgaccagt cgtttactct ttgccaacgg
    48421 aaaagtcaaa atctgatgaa gtgcatgtcg actcttctac gcaagtgact tttgaaacac
    48481 tcgttggaga aaatgattct ttaaaagtca gcatacagca ggcaaaagct gcgattcttt
    48541 atccaccgcg ggggttgcat acgattattt ttggagaaac tggtacaggg aagtcgatgt
    48601 ttgctgaatg tatgtatcat tttgcaatcg attcagagat gctttctgca gatgcgccat
    48661 ttgtttcttt caattgtgcg gattatgctc aaaatccgca actgctcttt ggacacatct
    48721 ttgggatcaa aaaaggggct tacacaggag cagctcaaga tagtcccggt ctaatagcca
    48781 aagcagacgg cggtatattg tttttagatg agatccaccg tttaccgccg gaagggcagg
    48841 aaatgctgtt tactttcatt gataaaggta tttaccgtcc gcttggagaa agtgcacaag
    48901 tacatgaagc atctgttcag atcattgggg cgacgactga atcttcagaa agtttcttat
    48961 ctacgttcaa tcgacggatt cctatggcaa tcaccttgcc gaatcttgct tcacgttcac
    49021 tggatgagcg ttatgaaatc atctctcttt ttatcaaaca agaagcgaat cgtttgaatc
    49081 aacgtatcga tatcgaaaaa gaagcgattc ttgccttcat gctttatgat gcggaaggaa
    49141 atatcggtca agtgaaacga gacttgaaac tagtctgtgc aaaatctttt ttacattacc
    49201 gtactcatca tgagaaaaag ctaatcattc gaaaagaaga actttccctt caagtacaaa
    49261 aaggattact gaaaatcaag gaaataccgg aacgtctcga ccgattcatg gacagcaaaa
    49321 gtcagtattt gacatttgaa ccaggatttg ctgatgttgt ctggtcacaa gatccagaac
    49381 gaaacatgca ggtctataac gatattgagg aaaaagtcac ttctctttcc gaaaccggtg
    49441 tggagaacat tgatctagag accctcattt caaaagatgt ggatgcttat ttccagacat
    49501 atgtcaaaga attgactaaa agttcgattc ccaaagatct tttgccagat gaaatctggc
    49561 ggttaaccaa tcaattgtat gatgtggctg aaaaacggtt agaccgtatt tataatgaaa
    49621 aagctcgttt tgcttttgct ttgcatctgc aaagtacatt ggatcgtgtg agagaaggtc
    49681 atatgatcgt ccacccagat ttgaataacg tacggaaaaa ttttaagagg gaattccagg
    49741 tagcaatcga tctttcaacg atcattgaag aagaagaaca agttgagatt ccttttgatg
    49801 aaatcggctt tattagtatg tttctttcta tcaatctagg agaaagtgag cctgttaaag
    49861 aaaacaaagt agatgttctc atattgatgc acggcagaca gactgcttca agcatgttgg
    49921 agatggcaca agaactatta ggaacaaaag tagggaaagc ttttaatatg ccactggtta
    49981 tggaagttca aacaatgtat gaagaagtgt tacaatatgt caaaaactat caagagcatt
    50041 tgacgaatgg cctactcttg ttaacagata tgggatcatt aaacaccttc agtgatttga
    50101 tttatgaaga gactggcatt cggacgaaag ctatcacgat gacaagtacc atgattgtga
    50161 tagaagcgat acggatggca agtgttggaa gaagcttaga agatatttat caaaatatcc
    50221 agctttcctt tgaatcgatc gtacgtgatc agttcaaagc ggaaaagtct gaaactttac
    50281 agcgtaaaaa agccgtaatc gtgacatgct ttactggtga aggagtagct gccaaattat
    50341 atcagcgtat tatgccagtg attaatcaaa ataaggtaga actgatccag atgcagtttt
    50401 tagaacgtga atcattcaaa aaacacatcg atgccttatt ggaagaatat gagatcaaag
    50461 caattgcggg aacagttgat gttgattatc aaaatatccc atttttttca gcctatgacg
    50521 tttttgatga tgaaaaacta aatattttaa agcgtatagc tgatgatgag atcccgacag
    50581 ctaaaattgt cgattcactt gctggatcat taagcgatgt cttttctatt gatgaactga
    50641 tccgttcatt gcaaaagaca gttcagcaga tccagaccga tttgtcgatt atcgtggaac
    50701 ctggagtaga tactggaatc gttatccatt tagccttcat gttagacgga ttgatcaaac
    50761 aagaaagcca tcggcaattt gagaaactgt ctattttctc aaaaatttat cgtttggaaa
    50821 tggatatcgt tcgggcaaac ttgatggcac tagaacgaaa atatcaggta aaaattccag
    50881 aagatgatat cgcatttctt acacaaatgt ttcttgaaaa taaaataaaa aaatgaacac
    50941 actaatcata ctgtttacac actaaacatc tgtgtgcgca ctataaaaaa gagctaaaaa
    51001 gcatgaaaac gctatttcag ctcttttttt tattggcatg cttcttgcgt tatataaaag
    51061 tgtaaaaaaa taaaaggagt gttaaaaatg gcaaaaaaaa caatcatgtt agtttgttca
    51121 gcagggatga gtacgagttt attggtcaca aaaatgcaaa aagcagcaga agaaaaaggg
    51181 atggaagccg atatttttgc ggtctctgcc tcagatgcag ataataattt agaatctaag
    51241 aatgtcgatg tattattatt aggtcctcaa gtacgtttca tgaaagctca atttgaacaa
    51301 aaacttgcgc ctaaaggtat tccattagat gtcatcaata tgcaagacta tggcatgatg
    51361 aacggagaaa aagttcttgc acaagcagaa aatctaatga aataaatcaa gtatgcagtt
    51421 gggggtataa caacgtggaa gatcaacaaa atctagaagc catcatgggg ttaatcatgt
    51481 ttggcggtaa tgcaaagagc gatgcaatgg aagcgattgc ggctgctaaa atcggtgatt
    51541 ttgagttagc ggataggaaa atcgctgatg cagaagaatc acttatacaa gcgcatcatg
    51601 cacaaacaga catgttgaca caagaagcac aaggaaatca tatgcaagtg acattattga
    51661 ctgttcacag tcaagatcac ttaatgacat ctattgcgtt tactgattta gcaaaagaaa
    51721 tcatcgaact ttatcgtcgc gtatacagcg aataaataca acttcttttt tgaacggaag
    51781 aagaaaaatt tttgaacgga ttttttattt tgttataagg agaactctct ttatataaaa
    51841 aacttatagg aggaagtaaa aaatgaacgg actatcaagt tggatggaga aatacatcct
    51901 gccggttgcc gcaaaaatcg gagcgcaaaa acatttagtt gctttgcgtg atgcttttat
    51961 cggcatactg cccgcaacaa tggcgggatc agtcgctgta atgatcaatg caattattcg
    52021 tgatttaccg caacagttta acagtaccta tgctgacagt ttagcagcag acaaaggaat
    52081 ctttgccgta ttgaatgtca tcatcggaat caatggtttt gtctggaacg gtacactagc
    52141 aatcgccgga ttgatctttg ccttttcttg ggggtataat cttgcccgag cttatggagt
    52201 aaatgatcta gctgggggga tcgttggttt agctaccttg attcaaggta tttcctttgg
    52261 tccagcatta tcagcagcat tagatgtgaa tgttccttca aatgtcgcag atgcaatcaa
    52321 tagttctgag attggtgcaa cgattgcaga tggcacactg tcagttggat tatggggttg
    52381 gctaaaacta gatcatttga atggaaacgc ttattttaca gttatgatca tgggagctat
    52441 ttcagtcatt attttttgta aattgatgct tgccaacatt acgatcaaaa tgcctgattc
    52501 agtaccacca gcagtatcta aagcatttgc agccatttta ccagcgacga tcgctttata
    52561 cgtcattgct attatcaatt atatcgtagg tcgtgtagct gatgggcaac tgatcattga
    52621 tttggtgcaa aaatatattg cagaaccatt cctaggatta tctcaagggt tgggagcagt
    52681 attgatcgtc acagtatttg ttcaagtatt ctggttcttt ggtattcatg gatcaaatgt
    52741 attggcacca gtgctagagg gaatctgggg acaagcacaa ctaatcaata ttgatatttt
    52801 ccaaaaaggt tataacggaa aaactggtac accagccgtg ttagatgcaa tcgaagatgg
    52861 aaaagcttat atgtgggtcc gcggatcgtt cgatgctttt gcatggtttg gcggatcagg
    52921 cggaacgatc gtcttactga tagctatctt gattttctct aaacgtgcag attatctaac
    52981 agtagctaaa ttatccattg ggcctggtat cttcaatatc aacgaaccag tgatgtttgg
    53041 tctgccaatc gtattgaatg caatcatgtt tatcccattc ttgattgctc cagtagtagc
    53101 aacagcaatt ggatggacag ctacttatct tggcctagtc gctccggtat cgcagcaagt
    53161 cacatgggta gtaccgccgt tcttattgtc attcttagca acaggagcgg attggcgggc
    53221 accgatcgta acattagtat gtatggtcgt gactttcttg atttgggcac catttgtcat
    53281 ctctgcaaac aaaatggacc ctgccgcagg cgaacaacaa taagatgaac gtgaggagcg
    53341 ggacgcttta agtttcgttc ctcataatga attttcgagg aggaactgaa atgattacaa
    53401 ttgccagtgc aatgcaacaa gatgaaatca aagaattgtt agaaggatac aatgaagaag
    53461 gaatgacttt tacatttaaa gaaaaacaag gaatcaagct gttctttgaa acaagtgcag
    53521 aagatccgga agttgcggct aaaaaagcaa aggaactaat caaagcacag ccttggggaa
    53581 cagtccttta ttttcaatca acagctgttt agaaaatggt ttaaaaagat aggatggttg
    53641 agatgataaa aaacggttta tttttatgta gtattggttc tttgatcgtg ttgtatagtt
    53701 tgaatccaca ttcgcaaagg tatgatttgt atagtatggt cacaggtctt tttctaacag
    53761 gattaggaat ctatttcttc atgaagggga aaaaaagaga agaagcaaag gagaaaaata
    53821 actaatggaa atcacgaaaa aattaaatat tccagcatcg tttttttacg ataaagttat
    53881 ggactctgtc cttttcgatg tacgtaaagc gaccggcaaa tcagtaacta gaaaacagct
    53941 gaaaaatttg gagtacgtca aacaattctc gcaaaataac cgggctcgca taaaaatcga
    54001 agaagtcatt gaaaaccagt cttataagtt tcgtacatcg acaacgaaga atgaattcgt
    54061 cgttcattat caaatcaaac cattggacga ttcgacctgt gaggttcatt acacagaaaa
    54121 aatggagtct tatggcatgc ttcaaaagtt gaatgatatg cttttaggaa caatcttgat
    54181 gtattttaaa cggagacgtt tcaaaaaaat gctagatatg atcgaagcaa cgtattaaat
    54241 caatgaaaca tggtactatt tagttattga aaaatgaagt aagctagaag gaatttttca
    54301 taggaagata gatctttcct gcgaatcctc actagctttt ttgtaggaag gggcagcaaa
    54361 atgacaaaca aagtaagaga gctaggtgta tcttcgattg aggaaatgtt tgatttagcc
    54421 acttatgcat ttaatggggc agatacacct gaaaggcgag aacgttttcg tacacttgcg
    54481 gagaattctt ggaattacgg attttttgat gaggaggatc ggctaacaag tcaagtcatg
    54541 gcgacccctt ttccagtgaa tttttacgga caagagtacc taatggccgg cattggctat
    54601 gttgcttctt atccagaagc aaggggacaa ggcgggatca atcagatcat ggaaaagatc
    54661 cttgaagatt gccgtgatcg taaagtaagc ttatcttatc tggcgccatt ctcctatccc
    54721 ttctatcggc gctatggcta tgaacaatca tttgataaaa tcagttatca actaaacagt
    54781 cgtgatgtgc cgtttatcaa aaaaaaatct ggaaaaataa agcgtatgga ttttgaagat
    54841 gcaaaagctg caatcagaag aatttatgaa cagatgccgg aaaaccaacg agctggtctg
    54901 aagcgcgaag actggtggta tacgtataaa ttcaagcaaa aaggcaatta ccagtttgct
    54961 ttgcattttg atgataatga ggaagcaacg ggatatatcg tttatcagct tgcaacgtct
    55021 tcctttatta ttgcggagtg gggatttttg gatcatgatg ctttttgcag ccttgttcgc
    55081 ttcgtaagtt ctcacaatgg tgcttttgaa acatttgaat attcatgcgg ctacggcggt
    55141 aatgatcaaa attatctatt agaaaatcca tttgcttctg taatgatcac accttatatg
    55201 atggcgagga tcgtagatat ttctttgttt ttggaaaatt atccatttaa aaagagacaa
    55261 gctgcatttg ccctacaaat agaagaagat cattatgcga aatggaatga aggaatcgtg
    55321 gaagtaacaa tcgaaaatgg aaaaaatcat ctctcaaaag tagaacaaac aaaactccca
    55381 atcgttcgag gaagtatcca acatatcacg cagctattat tagggtatcg taaagtggaa
    55441 gagttggtat tccaagaaag aatacaggtg acaaaagaat atgaagaaac gttaagctca
    55501 atcttgccac agcaacagcc aattcttaat gactattttt gataaaaaac gggtgatgac
    55561 aatatttttg tcaccaccct tttgtttttc atttggcatt tgaaggaaaa tgttaaagta
    55621 aatcctcttt tttcgtaaat ttgaattttt tgttttcttt tgttttaggg ttttcttttt
    55681 tgtggtcttg gattgcttct ttcgtaatct tttcccgatt ttttttagat gaatctaagc
    55741 gttctgcgta tactttttct tttggcttat cattcattgg aaaggacctc cctacattat
    55801 ttcattctac ctctagttta tcatctgtta aggactagtg gaaacgtttt gcctaactta
    55861 taagctgatt tttttagcag ataagcttgc aagtaaaaaa caaacaagct acaattgatt
    55921 tattgaaatt gttcctgtag ctcagtagga tagagcaatc gcctcctaag cgataggtcg
    55981 ctggttcaat tc
//
LOCUS       DAIGSZ010000011        54448 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.011, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000011 DAIGSZ010000000
VERSION     DAIGSZ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.011"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(24..959)
                     /gene="murB"
                     /locus_tag="NOB31_000688"
     CDS             complement(24..959)
                     /gene="murB"
                     /locus_tag="NOB31_000688"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HCI0972924.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1032..1952)
                     /locus_tag="NOB31_000689"
     CDS             complement(1032..1952)
                     /locus_tag="NOB31_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0972925.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2065..2817
                     /gene="xth"
                     /locus_tag="NOB31_000690"
     CDS             2065..2817
                     /gene="xth"
                     /locus_tag="NOB31_000690"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HCI0972926.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3681..4214
                     /locus_tag="NOB31_000691"
     CDS             3681..4214
                     /locus_tag="NOB31_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HCI0972927.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(4704..5228)
                     /locus_tag="NOB31_000692"
     CDS             complement(4704..5228)
                     /locus_tag="NOB31_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0972928.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(5221..5694)
                     /gene="tsaE"
                     /locus_tag="NOB31_000693"
     CDS             complement(5221..5694)
                     /gene="tsaE"
                     /locus_tag="NOB31_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HCI0972929.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(5817..6797)
                     /gene="pta"
                     /locus_tag="NOB31_000694"
     CDS             complement(5817..6797)
                     /gene="pta"
                     /locus_tag="NOB31_000694"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HCI0972930.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(6950..7630)
                     /locus_tag="NOB31_000695"
     CDS             complement(6950..7630)
                     /locus_tag="NOB31_000695"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCI0972931.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            7756..8625
                     /locus_tag="NOB31_000696"
     CDS             7756..8625
                     /locus_tag="NOB31_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0972932.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            8651..9166
                     /locus_tag="NOB31_000697"
     CDS             8651..9166
                     /locus_tag="NOB31_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972933.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(9213..9806)
                     /locus_tag="NOB31_000698"
     CDS             complement(9213..9806)
                     /locus_tag="NOB31_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0972934.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(9831..10010)
                     /locus_tag="NOB31_000699"
     CDS             complement(9831..10010)
                     /locus_tag="NOB31_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972935.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(10087..10596)
                     /locus_tag="NOB31_000700"
     CDS             complement(10087..10596)
                     /locus_tag="NOB31_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972936.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(10692..11072)
                     /locus_tag="NOB31_000701"
     CDS             complement(10692..11072)
                     /locus_tag="NOB31_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0972937.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            11402..12151
                     /locus_tag="NOB31_000702"
     CDS             11402..12151
                     /locus_tag="NOB31_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HCI0972938.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(12472..13689)
                     /locus_tag="NOB31_000703"
     CDS             complement(12472..13689)
                     /locus_tag="NOB31_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI0972939.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(13947..15224)
                     /locus_tag="NOB31_000704"
     CDS             complement(13947..15224)
                     /locus_tag="NOB31_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972940.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15303..15947)
                     /gene="pcp"
                     /locus_tag="NOB31_000705"
     CDS             complement(15303..15947)
                     /gene="pcp"
                     /locus_tag="NOB31_000705"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HCI0972941.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16146..17090)
                     /locus_tag="NOB31_000706"
     CDS             complement(16146..17090)
                     /locus_tag="NOB31_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HCI0972942.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17092..17778)
                     /locus_tag="NOB31_000707"
     CDS             complement(17092..17778)
                     /locus_tag="NOB31_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HCI0972943.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18252..18572
                     /locus_tag="NOB31_000708"
     CDS             18252..18572
                     /locus_tag="NOB31_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HCI0972944.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            18726..19631
                     /locus_tag="NOB31_000709"
     CDS             18726..19631
                     /locus_tag="NOB31_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0972945.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            19628..20401
                     /locus_tag="NOB31_000710"
     CDS             19628..20401
                     /locus_tag="NOB31_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI0972946.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(20582..22006)
                     /locus_tag="NOB31_000711"
     CDS             complement(20582..22006)
                     /locus_tag="NOB31_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0972947.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            22217..22663
                     /gene="nrdI"
                     /locus_tag="NOB31_000712"
     CDS             22217..22663
                     /gene="nrdI"
                     /locus_tag="NOB31_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCI0972948.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(22728..24710)
                     /locus_tag="NOB31_000713"
     CDS             complement(22728..24710)
                     /locus_tag="NOB31_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0972949.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(24724..25620)
                     /gene="murQ"
                     /locus_tag="NOB31_000714"
     CDS             complement(24724..25620)
                     /gene="murQ"
                     /locus_tag="NOB31_000714"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCI0972950.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(25623..26684)
                     /locus_tag="NOB31_000715"
     CDS             complement(25623..26684)
                     /locus_tag="NOB31_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI0972951.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(26895..27461)
                     /locus_tag="NOB31_000716"
     CDS             complement(26895..27461)
                     /locus_tag="NOB31_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI0972952.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(27489..28991)
                     /gene="eat(A)"
                     /locus_tag="NOB31_000717"
     CDS             complement(27489..28991)
                     /gene="eat(A)"
                     /locus_tag="NOB31_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCI0972953.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(29249..30370)
                     /locus_tag="NOB31_000718"
     CDS             complement(29249..30370)
                     /locus_tag="NOB31_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI0972954.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            30496..31437
                     /locus_tag="NOB31_000719"
     CDS             30496..31437
                     /locus_tag="NOB31_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI0972955.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(31587..32483)
                     /locus_tag="NOB31_000720"
     CDS             complement(31587..32483)
                     /locus_tag="NOB31_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HCI0972956.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            32752..34092
                     /locus_tag="NOB31_000721"
     CDS             32752..34092
                     /locus_tag="NOB31_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0972957.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            34310..34753
                     /locus_tag="NOB31_000722"
     CDS             34310..34753
                     /locus_tag="NOB31_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HCI0972958.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(35257..36675)
                     /gene="nhaC"
                     /locus_tag="NOB31_000723"
     CDS             complement(35257..36675)
                     /gene="nhaC"
                     /locus_tag="NOB31_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCI0972959.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(37078..38301)
                     /locus_tag="NOB31_000724"
     CDS             complement(37078..38301)
                     /locus_tag="NOB31_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCI0972960.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(38332..39171)
                     /locus_tag="NOB31_000725"
     CDS             complement(38332..39171)
                     /locus_tag="NOB31_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCI0972961.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(39188..39868)
                     /locus_tag="NOB31_000726"
     CDS             complement(39188..39868)
                     /locus_tag="NOB31_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0972962.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(39870..40943)
                     /locus_tag="NOB31_000727"
     CDS             complement(39870..40943)
                     /locus_tag="NOB31_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0972963.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(40999..41237)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(41280..41513)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(41590..42261)
                     /locus_tag="NOB31_000728"
     CDS             complement(41590..42261)
                     /locus_tag="NOB31_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0972964.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(42348..45026)
                     /gene="mgtA"
                     /locus_tag="NOB31_000729"
     CDS             complement(42348..45026)
                     /gene="mgtA"
                     /locus_tag="NOB31_000729"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCI0972965.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            45685..46122
                     /gene="ndk"
                     /locus_tag="NOB31_000730"
     CDS             45685..46122
                     /gene="ndk"
                     /locus_tag="NOB31_000730"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HCI0972966.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(46144..47010)
                     /locus_tag="NOB31_000731"
     CDS             complement(46144..47010)
                     /locus_tag="NOB31_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0972967.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(47170..49263)
                     /locus_tag="NOB31_000732"
     CDS             complement(47170..49263)
                     /locus_tag="NOB31_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI0972968.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(50012..50635)
                     /locus_tag="NOB31_000733"
     CDS             complement(50012..50635)
                     /locus_tag="NOB31_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972969.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(50794..52191)
                     /locus_tag="NOB31_000734"
     CDS             complement(50794..52191)
                     /locus_tag="NOB31_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0972970.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(52223..53194)
                     /locus_tag="NOB31_000735"
     CDS             complement(52223..53194)
                     /locus_tag="NOB31_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0972971.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            53568..53993
                     /locus_tag="NOB31_000736"
     CDS             53568..53993
                     /locus_tag="NOB31_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972972.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT        15717 a        11284 c         9619 g        17828 t
ORIGIN      
        1 cttattttaa gttccattac ttattaattg gctaaacttc tgcttgtttc tgatattgct
       61 tgtttttctc caatgatccg cacttctgtt tctaaagaca catcaaattt ttctttgatt
      121 acttcttgga tgtgcgcaat caattcaata taatctgtcg ctgtcgcatg atcgatattg
      181 acgatgaatc cagcatgttt ttcagagact tgtgcaccgc cccatttcag gccttgcaat
      241 cctgcttgtt ggatcagctg acctgtatag tgtcctactg ggcgcttaaa gacacttccg
      301 catgaagggt attctaatgg ctgttttgat tgacgcaatt cggtcaactc atccattctt
      361 gctttgattg cttcataatc ccctgtttgc aaactgaatc gagcttccaa tacgatagca
      421 cgtaattctt ggactttact gtgacgataa gaaaatacca tttcgtcttt tgtcaaagtt
      481 ttcaatgttc catcttcaag caaaagatcc acttcagcaa aaacatcttt gatctctccg
      541 ccatacgcac ctgcattcat ataaaccgct ccaccgacac ttcccgggat gccgcaagca
      601 aattcaaatc cagtcaatga ttctgccaaa gctgcataag tcgtatcaat cagtgaggca
      661 cctgcttccg caatgaccat cgttcctttg acatgaatct gtttcatttc agtcagcatg
      721 atgactacac cgcgaatccc gccatcttga acgatcagat tgcttgcatt tcctaatacc
      781 atccaaggta tatcatggat tcggcaataa tcgatgattt gctttacttc ttcttgtttt
      841 ttcgggaatg caaggacatc agctggtcca cctgttttcg taaacgtata gttcatcaat
      901 ggttcatcaa acaatatagt aatcgtggct aagctttcaa ctatttcttc tttattcact
      961 gaggattttc ctttcttttc tcaaacgtcc tcattattct atcacgctta atacaatctt
     1021 gccagtcttg ttcaaagttg atgacggtag tgatctttaa gcacttcctc acataattca
     1081 tgacttctta caacttcttt ttgtttaagc aattctgttt ccgatttacc taaacggatc
     1141 tgagaaaaga aggcctctac cattggctca aacccgcgtt tgactagcgt gtttgtccag
     1201 tcgccaaatt ctttcacttt ttttccatca gcatcttgaa tgacaagctg ggtcagatcg
     1261 tttacttcat aagtaccatt tttacttgtt acttgatatt tttctatatt agcgccactt
     1321 gctaaatcca tcgttaaaat agccgtttga ttttgtgttt ctaattgtaa aatggcatat
     1381 tccaaaaatt cctttgtttc tcttatctgg tattttgttc tcaaaatggg ttcatctaat
     1441 aaatacacag ctgtatcaat aagatgtaaa aacaaatcat aaaggacgaa ctctgtcgtt
     1501 tcttttgccg ctattcgatt tttttgcagg tggatcaacc gcttatctgg gatacgtttc
     1561 aattcttcta ccataggagc aaagcgccgg ttgaaaccga tcatcaaaat tatttggttc
     1621 ttatcagcta attcttgcaa ttcacgaact tcatttagat ggacactcag tggtttgtca
     1681 atataaacat ggataccatt ttctagacat tttttggcta attcataatg tacttttgtt
     1741 gctgcgtgga tcatacatgc ttcgattttt tcttctaaaa gctcatcgat cgtttcatat
     1801 agatgttgga acccgtactc tttttgaatt ctttcttttg tttctttatt tcttgttgca
     1861 aaataaaaat caagtgttcc ttgttttttc gcataagttg gtaaatatgc tttttctgcg
     1921 atattcccta caccgattac accaatcttc atctactttc ctcctggatc atttagttac
     1981 tttcatctta caccattttt tactaaaatg aggtacaata gtatcgcaaa ggtaaggaaa
     2041 ttaattcgaa ggagtgtgct tttattgaaa tttatctctt ggaacgtaaa cgggcttcgt
     2101 gccatcgtaa ataaaaattt tttagaagtt tttcatgagt tagacgccga ttttttctgt
     2161 ctgcaggaaa cgaaactcca agcaggacaa attgatttag atcttccagg ttattatcaa
     2221 tattggaatt acgcggaacg aaaaggctat tccggcacag cgatttttgc taaaaaacca
     2281 gcattgaatg ccacttacgg aatgggtatc gatatccatg atacagaagg ccgtctgatt
     2341 actttggaat attccgattt ctttcttgta acctgttaca cgccaaattc tcaaagcgaa
     2401 ttaaaacgtt tagattaccg attagaatgg gaagaagcct tttataatta tttggaaaat
     2461 ctaaaaaaac aaaaaccagt catcgtgtgt ggggatctaa atgtcgctca tcaaaagatt
     2521 gatttgaaaa actggaaaac gaatcaaaaa aatgctggat tcactccaga agaaagagcg
     2581 gctctttctc gactgttgga taacgggttt atcgatacat tccgttattt ttatccaacc
     2641 caggaaggtg tctactcttg gtggaactac cgattcaatt caaggaaaaa caatgctggt
     2701 tggcggatcg attacttttt gacgagcaaa gatttagagc caggactagc tgatgcaaag
     2761 atccatacgg acattatggg cagtgatcat tgtccagtag aattagattt gaaataaaga
     2821 ggttgtgaaa aagtcgttta gtttcgagta ttaagaaaaa ttttgtgaaa atggctttcc
     2881 acattttgca taaatttggc ataataccga gaaactggct tttgaacact gtttatcgag
     2941 agattgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaaacaaa aatagttcct
     3001 catatttttc gtttggttgg gcttattacc gcagatacaa gcttttgaac accgtttatt
     3061 aagaggttgt gaaaaagctg cactgcatca agtaataaga acagccaaac aaaaatagtt
     3121 cctcatattt ttcgtttggt tgggcttatt accgcagatg caagcttttg aacaccgttt
     3181 attaagaggt tgtgaaaaag ctgcactgca tcaagtaata agaacagcca aacaaaaata
     3241 gttcctcata tttttcgttt ggttggactt attaccgcag atgcaagctt ttgaacaccg
     3301 tttattgaga agttgtgaaa tcagcgtcct gacctgagta ttagagaaac aaatggcaaa
     3361 atagttcctc atattttgct attttttgag ctaataccga gggtcagctg attgaacacc
     3421 gtttagtgga gaagttgtga aaaagtcgcc tactttcgag tcgtaagaaa tttttttgaa
     3481 aatggttcct cacaactttg cataaatttg acttaatacc gagaagtcat gatccccatc
     3541 taactccaaa tcacaaggaa tgagttcaaa aactagcttt tctcaacaaa tattacataa
     3601 aaaattctat gttttttgtt aaatttattt gcttttttca aaagtatgtt acagtaattt
     3661 cccaaggagg ttttacagaa atgaattttg ttgccatgga ttttgaaact gccaatcatc
     3721 agccttatag tgcttgttct cttgcgctag tcatggtaaa aaatagccag atcgttgatg
     3781 aattctatac attgatacag cctgagactc cttttttctg gcgaaatgtc caaattcacg
     3841 gaatccatca agaagacgta cgcaatgcgc cgaaattccc agaagtctgg caaactatcc
     3901 aaccatattt tcaaaaaaat cgtttagtcg ttgcacataa tgctgctttt gatacaaagg
     3961 tcttagcggg atgcttagat tattatcatc ttgaacagcc taattatctt tctttatgta
     4021 cagtgaaaag tagccgtcgc ctgtttcctg aatttccaaa tcatcgattg aacactgtgt
     4081 gcgaaaattt gaacatccaa ttagatcatc accatgatgc attggaagat agtcgtgcat
     4141 gtgcggaaat cctgctttat caagaaaaaa aattcgggac agatccattg aaaaaacttg
     4201 tgactataaa gtaaaagaat acttatgaaa cacacaaaga ggtcgtgagc ctgccgtttc
     4261 actccgagtc acaaggagca atttcaaaaa atagcttctc atgtttatta aatattgtga
     4321 ctggtgaccg aggagctggc aggagaacac cgtttattgg agaggttgtg aaaaagctgt
     4381 tctgcatcaa gtaataagaa cagccaaaca aaaatagctt ctcatatttt tcatttggtt
     4441 ggacttatta ccgcagatgc aagcttttgg acaccgttta ccaagaggtt gtgaaatcag
     4501 cgttttgacc tgagtattag agaaacaaac ggcaaaatag ttcctcatat tttgccgttt
     4561 tttgagctaa taccgaaggt cagctgattg aacaccgttt attcaaaaaa aatggactgc
     4621 gacacgactt ttgtcacagt cccttcgtgt gtttttctgc cttctcaaaa ggatgacagt
     4681 ttctcactct tttcctattt cttctattca atcaaataac tcattttata tacatctaaa
     4741 aattcaccta gatctgttct tgcccctcta ggcatgaccg cttcgatttg gaagcccatt
     4801 tttcggtaaa ggtgtacggc tctttcatta cgaacttgaa cgtcaagctc caatcgaaaa
     4861 agtacaccca tttccttcgc ccaactgatg atttcttcta gcataagagt gcctagtccc
     4921 attccccaat attcctgcag aatactgata ccgacttctc ccacgtgaga caaacgaaat
     4981 tgactgtctg ccttgacaga tgctgttcca ataatcgtcc cttcatagat tgcaagcagc
     5041 aataaattat tattgctttc gtatatataa tccaactctt cttctaaggt ttctggtggt
     5101 aacaggagtt ctgcttcatc caaaactaaa aattctgtct ccttattaac ttgtcccatc
     5161 atcaaaagaa tgtcttttgc atctcctggc actgcttccc gcaagatgat cccaacttct
     5221 tcactcatga ttttcagccc atttttctag aattcgctgt ttgaaggttt cactttgctc
     5281 cccgtatgag attagtttca cataccgctt ttctaaatct gtatcacttt tttctaaaat
     5341 cagttccaaa taatcctccg gcagtgcttc ttctaataga tttccccatt caacaacgga
     5401 aagcccatca ccttcaaaat attcatctaa ccctaaatct gctccgctag ctgctacccg
     5461 ataaatatcc atatgataca acggaatccg accttgacta tattctctaa taatcgtgta
     5521 tgtcggactt ttgatcattt gcgttatccc taatccttgg gcaattcctt tcgtcaacgt
     5581 tgttttaccc gcacctagat caccagtcaa tatcagattg tcacctggca ttgcggaatg
     5641 accaattgcc tctgcgaatt gttctgtcat tgttaatcct gatagttcga tcatttttca
     5701 tcttctcccg ctcttctttc tttttgccag tatatcgcgt aatgaagttt ttttaaagaa
     5761 aaaatgaact agtcaagaac agcagctgct gtttttggct agttcgcgtg tatttgttaa
     5821 tcaatcaatg tttgtgctgc tgtgataatc gataatttat atacatcttc ttcatttgct
     5881 ccacgagaca aatcagaaac cggtttgttc aagccttgta gaattggtcc gattgcttca
     5941 aagttaccga aacgctgagc aattttatag ccgatatttc ctgactgcaa ttctggaaat
     6001 acaaagactg ttgcttgacc agctacttct gaatctggcg ctttcagttg tgcaactgaa
     6061 ggaacataag aagcatcaaa ttgcaattcg ccgtcgatca tgtattgtgg cgctagtttt
     6121 ttagcgattt tagttgcttc aactactttg tctacttctg gcgatttcgc tgagcctttt
     6181 gtcgagaagc tcatcattgc tacttttggt tcgatatcga acaattctgc tgtttttgca
     6241 gaatctacgg cgatttcagc caattcttgc gcagttggat tcacgttgat cgcacaatcc
     6301 gaaaagacat atttttcttg atctcttcca cgtaccatga tcatcgctcc gcttgtccga
     6361 ctgatgccag gctttgtttt gatgatctga agtgctgggc gaacagtgtc gccagtcgaa
     6421 tggatcgctc cagagaccat tccgtctgca atccccatat acgtaagcat cgtaccaaag
     6481 taattcacat cttttaaaat cttttctgct tgttctttgg atgcctttcc atttctacgt
     6541 tcaacaaaag tatccaccat ttcatcccac ttatcgtaat tatcagggct gatgatcgta
     6601 aagctagatg ttttgattcc tctggcatgc gctgcatttc ttatttcttc ttcgttccct
     6661 actaaaatgg gttccacaag ttcttctgct ttcaaccggg cagctgcgcc taaaatacga
     6721 gcatcagtag cttccgggaa aacgattttg atcccacggc gaacaatttt aaatcttaaa
     6781 ctatcaaaca attccacaag atgacctcca gacgttttta tatgtattat catacactat
     6841 tccagaaaaa aagaacagtt tattttatct gtatcagtca aaaatgctgg aaaaattaag
     6901 tttttcacat acaaagcgaa ctgcactata acaggaaagc gctgttttat tacactgttt
     6961 caggcagttg ccaatcaatc ggttcttctc ctaacgcaag gagcgcatca ttcgttttcg
     7021 agaagggttt ggaaccaaaa aagccacgac ttgcagataa cggactggga tgtggagatg
     7081 ttatgatgat atggcgactc ttatcgatca ttttgatttt ttcttgtgcc ggttttcccc
     7141 acaagataaa cacgattggt ttttcccgtt catttaattt ttcaatgatc gtgtctgtta
     7201 atctttccca acctttcccg cgatgagaat acgcttgccc ttcccgaacg gtaagaacgg
     7261 tgttgagtaa aaggactccc tgtttagccc atgacactag atttccatgt tgaacaggtg
     7321 cgattccaag atcatcataa agctctttat agatatttct taacgatggc gggatcttta
     7381 cgccaggttg cacagaaaaa gataagccat gagcttgatt ttctccatga taaggatctt
     7441 gtcctaaaat caccacttta acttcttcat aaggagtcaa ttccaatgct tcatagatat
     7501 gatacatatc tggatggatc ttttgggacg catattcttt ttttaaaaat tctcttagat
     7561 gcagataata atcttttgaa aattctgagg acaaaacttc ttgccaactg ttatgaatga
     7621 tttctttcaa aaactccacc tcctaataaa aagaataact cacattttct tcaatcacaa
     7681 gggacaatct tcaccctcag cacttgatta atatggtaaa ctaggaacaa gaagcagaaa
     7741 ggaacgataa tcattatgat caaattaatt gcatcagata tggacggcac attattagat
     7801 gcccatatga gtgtttctcc tgaaaatgcc gaggcgatac gttttgcaaa tgatgccggt
     7861 gttgagttca tggtcgctac tggtcgaaac tatcaagaag ctcgcgcagc tttagatgag
     7921 gtaggaatcg attgtgcgat gatcactttg aacggggcac aggtatttga taaagaagga
     7981 aattcattgt ttaccgtgtc gattccaaat aatcaagcaa tctctgtttt agatattcta
     8041 gatgctaacg gtatttacta tgaagtagca accaacgatg gtctttattc tgaaaatcaa
     8101 gcgaaacgaa ttgaaagttt tgcttccatg gtggctaccc atttacctca ccttacgtat
     8161 aaaatggcga ttgccatggc ctcagctaag ctggagttat tgcacatcac atacgtggac
     8221 agtattcgtg ctattttgga agaaaagaat ctggaagttt taaaaattat ttgttttcat
     8281 acagaagggc cagctgtatt aggtccagtt ggaaagcaga tttctctttt aggcgatcta
     8341 gccgttactt cctctggtca aaacaatatc gaagtgaacc ataaaaacgc tcaaaaagga
     8401 attgctgttg cccatgtcgc tcacgagcgt gggatttctt tagaagaagt catgacgatt
     8461 ggcgataact tcaatgatgt cagcatgctg caagtagcag gagtcagttt cgcaatggga
     8521 aatgcagaaa tcgaagtaaa agattatgcc aaatatacaa cggacacaaa ccttgaatct
     8581 ggcgtaggaa aagccatatt gcgcgcgatt gcagaagact tgtagtttta tctagaaaag
     8641 agggatatag atgtcagaat ttttcattca ggaaaagcag cttggacgtg caactcggac
     8701 aattgtcaaa aacgaaaaag gacattccct gtttttgatg gttggtcgct ggggaacaaa
     8761 gggcgatgca ttgtctcttt atgccatgaa tggcgatctc gttgctcaca tcaagcagat
     8821 aagcctgaca ttcggtacgc gttttgagct gtataaagag ttcgaaaagg tgggaaccat
     8881 gcagaaaata ttcaattggc ccggtgactt ttattatatt cgtagacttc actggacagt
     8941 ccaaggtgat atctataatc atcaatatca aatccatcat ttcaatcagc aaatcatgaa
     9001 aatggataaa gcaacacttt tttcaggaga ttactatgta ttggatgtct caaatgatga
     9061 agatgctcca gtttgtattt gtattgctgc ggttttagat tactggctct accgtaaaga
     9121 caaaagtcgc gataagcctg tttcttaccg acttaactta agttaaaaag atgtacctga
     9181 aatgcggaaa tacgcatttc aggtacatct ttttagatat tcttttgcat atgatcataa
     9241 agatgaccac tgatcatccg ctgaccgaca actttgaagt catggcgttc gtataatttt
     9301 ttagcctttg gatttttttc atccacactt agaccgatga cggagcgatt agctttcttc
     9361 gccaatttag gtaatgcttc taataatcgc gaaccgatgc cttgtcctct aaaatcttct
     9421 gatacactga tagagtccaa ataccattcg ttgggaaacg tttctttatc aatgaacaaa
     9481 cgtgtagacg catctagctg atatttctct aagataggta ccagtggctg atcgatgatt
     9541 gattcttctt catctgtata accgtaagca actcctgcaa ctttaccgtc tatttcttct
     9601 acgatacctc gtgaataact gtaacgataa tttggatcag tgattgcttc ttctaaaatc
     9661 tctaaagtct tttgttcccc tgtctgcttc aaaaatggca gttccatatc ttttagaatc
     9721 actaagatca atggggcgat ttctggagca tcttcttttc tcgcaaaacg aatcatagtt
     9781 tcctctcctt ttctccattc taacatgcag aaaaagaaat cgcaaaatcg ttattttaaa
     9841 aaatcttcaa tcttttcagt aatgaaataa ccatgagtaa cgattcttgc cgcttcagtt
     9901 cggcaataag ggcagacgac tggcatttct ttatcattat gttcgactac attattgact
     9961 tcttcgtatg caaatttttt tccgcaatta gggcatttca ttttttccat gttatctcaa
    10021 cttcctttca tctttactct cttagcttac tcttatattg taaaaaagag aagcaatatc
    10081 cttcttctat gcagatatcc atacctgacg gtcctgttct ccatctatta atcggacttt
    10141 ataataagga cgttcatctt tgactagaag tgtccactct ttcacttttg cttttttccc
    10201 gtagtagctg actgcttcct tcatcgctgc ttgcggttgt ttgaactctt ccgttttttc
    10261 tatatcaaaa agatgttctg cggccttttc cgtgtcattt cgtacggttg ttttcccagt
    10321 ggatggattg actgctatga cttgtccttc acaaaaaaac tggtattcat atgttgcatt
    10381 cgtaggattc tccaaatctt tttcaactgc aaaatgaata gcagatatgt tatgttcttt
    10441 tgtttcgttt tttacgattg ctgctgcttt tttcaatgag atccgatatt cctggtcact
    10501 aatatcatcc atgtgaaaag cggcattgag cagtcccgtc ataccggtaa tccctattac
    10561 gatgagggca gcaacaccaa acatcatttt tttcattctt cattctcctg tttctttttt
    10621 ttaaagaata tcaagaaatg aacgaatgaa aaatcgaatg aaacgaaaaa aaagtgacaa
    10681 ttttgttatc tttattcgtg cagttctaat ggcaatccgt ctggatcaaa gaaaaacgtc
    10741 attttttttc ctgtaaaggt atcttctcta atcggttctg attcgatccc taaggactgc
    10801 aattctgcaa ttgtttcttc aatatcgtct actttgaaag caagatgacg caagccacaa
    10861 gcttctggat agtttggtcg ttgtggcgca ttagcaattc caaaaatctc caattcagca
    10921 cttcctagtt tcagatctaa tttatagtca tctcgttctt tgcggtaatt ttctctgatt
    10981 acttcaaatc ctaatttatt aacataaaaa tcacgtgatt tctgataatc tgaaacaatg
    11041 atggctatat gatggatcgt tgtaaggttc atatgagcac tcctattctt cgtttaagct
    11101 cggatctata ttaatctcca gttccattgt aaatgtgtca gattgaaaaa aatagctgtt
    11161 tttccttttt ataagaaaaa aggcaaaaaa aacagaaagt aggtcctcca agacactctt
    11221 cctgttccca atataataaa tgaaagtaag aaattatatt ttcaagaaaa caaacagaaa
    11281 attatcataa cacaaattat ttataattga aagactagtt ttttttcaag aaaagcatac
    11341 aatagattgt gttagtaaat acagaacaca ctacatttag tgtcttaagg agtcctcata
    11401 catgaagtca tattttcagt ttttagctca tcagctaaaa ggctggccgc aacaaaatta
    11461 ttatcttttc tttttcagtc ttggctgcca ggtcatgact cttgtcaata gtcccatcac
    11521 ttggctgtcc gttattacat ttatcggtac cacgcttggt gtattgtgta ttttatccat
    11581 caatgcggca aaatcagtca acggtatttt aggtattttg tctgcgattt gttttattat
    11641 cgttgggttt tcagcaaaga actatttaag tatcggtgaa cagattgctt atatgatcac
    11701 attggatatc cccgtattgt taagtaaaga atggaatcat aatatggctt caaaaatccg
    11761 aaaattcact ggaaaaagct ggtttatcgc aatcatcagt actttccttg tctatcttgt
    11821 ttcaggattc ctgattggtc gttatacaga tgatcctcgg ccgtgggtag atgccattgc
    11881 tttttctatt agcttgactg ctggtatcat cagtttcttg cgttacaaca accaatatta
    11941 ctggtggtta gcttcagggc ttgctcaaat ggtcctttgg tatatttcat ttacgcatgg
    12001 atctgcaagt ttggcgatgt tcgtgaacag ctctgtttac ttgctgaatg atgtccttgc
    12061 atttaccgtt tcaccttggt ataaccaaaa agaacgtgaa cgtatgcaaa aaatggaaga
    12121 agaatactac aacgcacaac aacacgcata aaaaaactga gcgtgggaca aaagtaaaga
    12181 acacttttgt ctcacgctct aaacacgtat aaacggcgga atcagaagca actccttcgg
    12241 aaataagctg aaattcacaa aaatttgaaa agcaattttc gtgaatttct tcttatttct
    12301 tggagttaaa cgcttctgtc ccagcctcta tttcctacga ttagtcaagt aaaaggtgca
    12361 agaaaaatag ctcgtaaacg aaagcgacaa aatcaaagca caccaaataa agccccgttc
    12421 gtaaaaaatt ttcgatctgg gcaaagaagt ggtatactgt aagtggttta gttaatggtc
    12481 cactgagacc gcgtacgcat agtcgtactc tgtatgtgcc ctaaccatag cgtgcataca
    12541 tttcagaagc ttgttcatac aagcaactgt ggcaacctta tctttcttag ggataggttg
    12601 cttttttaat ttgtagtaat aatcgacaat atgattagga gctgcgcgtt gctggcgaat
    12661 catatttcga atggtgaaga aaataatttt ccgtgctttg ggattaccac gcttattgat
    12721 gcggtcttgg ccagtatact tacctgaatg ataccgtcgg atgtcgattc cgacaaaggc
    12781 attcaattgt ttatgggttt taaatcgtgt gatatctcct aattcaccga gcaataaagc
    12841 ggctgtgagt gcgccaatcc cagggaacgt ttggtacaac aaaaagcaag gagagccttc
    12901 ggcttttttg atcatttgtg tcgccagtgc ttttttttgt tcgagtaaat cttggagaag
    12961 ttcggcgtaa tagatcgttt tttgacagtg gatactgtct ttttcaacag ctggataggc
    13021 acactgtgca tagtggatga tttgatctgc cttttgctcg gcacgattcg cggagatttt
    13081 tttccgtgtt tcgttgatca gtttattttt tatttttgtc cgagtagatg ccaatacaaa
    13141 atctggatgg ggaaaaagac ggatcaatgt caatgcgtaa ggggtcagcc tgtttgaaaa
    13201 gaactgttca agctctggaa aagtcaattg aaggcagttg tgtaaatcca tgcgcagacg
    13261 agtgattttc ttctcaattt cttgataaaa acgggctaaa tcgcgcatct ctaagtaaaa
    13321 attgctttgt acttcttttg gctgacgttg atttttaaga tgagtctgtg cgagccggtg
    13381 ggcatccgat ttatctgttt tccaactgcg taaggtgctt tcttccatct gttttttcgc
    13441 ctctaacggg tttaacaaac agtaagaaaa gtgatgatct tgaaagaact tttcgactgg
    13501 tctggaataa atccccgttg cttcaaaaac aatcaatgga cgctcaggca agtgctggat
    13561 ctcttcgagt aatgcatgaa atcctctttg agtgtgttca atctcgtctt caaataagca
    13621 ggtgtcgtct ttgtatagga cactgtagct gtgtcccatt gaaacatcta atgcaagaat
    13681 gtaaggcatt tgttttcctc ctttttaagt tttgaaagaa ctttactgct tcatttcgat
    13741 tccaatttcc tatacacggg ctcatggccc caacatacgt aaacctgatt ctaaaatgac
    13801 agtaaagaag ttcggttttt gatagggact cgtagtcctc aaggctttgt tcgaactttc
    13861 tttcactctt cactataatc taaaaataga aaatagagga gaacatcatt cgtcaatgat
    13921 gttcccctct aatcttagta tgttttttat agtaattcct tcagatactt tcttgcctca
    13981 tcattgaaac gcagtgattc ttctaacttc tgataatatt ccaacgcttg tttctgagct
    14041 tcagtaaaac gataatgttt tcctttccat ttgtcgattg tctcttgcac atttccagat
    14101 tggatatctt tcactactag ttgccatttt tcttttgaga ctgtacggtc tttcttatca
    14161 gcagattgta tagcttctcg ttctttacgc aatactttta aaaaaccatt tctgactatc
    14221 cgaggaatgc tgtcgaagaa cccttctgta aaaccatagc gacaatattg cttccaaata
    14281 aatagataga tttttggttg gatgaatcgt tggtttttcg caaaatattc catctgagca
    14341 gtgacttctg gtgttcgttg acgttttgtc tttctcaaca cggaaataaa tgtttcaaaa
    14401 taagcattag gatgtactgg cacttcttca tatacgatgg attgccaatc tttacgtaaa
    14461 aatgcgcgat agttgatcaa gaattcttct acatccttta ctaattcttc tgcaaagtcg
    14521 tcaaatagtt ctttttttat ctgtcgcttt tttgactgcc cattgatgtg ttcacttatt
    14581 ttcttgattt cattttccaa tgcttgataa tccgctatgt aaatcggcat ttctacttgg
    14641 cgaaattctg cgagccgctg agctaatttt atatccggta aatatggctg tttcatccga
    14701 cgattttggt acaagacaaa acagtatttt tgccatagtc cttcaggaaa atcgatattc
    14761 ttctgcttaa gccataataa ttcgtctaag gccagatcaa cttttgtcat tccctgatgg
    14821 atcgaagctg ccactgtcgg agagacatgc aggtgatcgg caaagtggtt gatgcctagt
    14881 tttaggatct ttccggtttt tggcgattta acgatgtatt gcacttttaa ttctctacca
    14941 cactcacaat acaatttttg ctggcttcgt tttgttcgaa aaaacggatt gatcttgaag
    15001 tcagaaaaca cccaatctgt tgcagctaaa taatgttctt ccataaaacg agagctgatt
    15061 agatatcggc ggtgcttatc gactagttcc cgctgttttt tcgttaattt tgcatagatc
    15121 tcccaacgtt gactgcttgt gtattgttta gaaattttga tgggatagct tttgctgatt
    15181 tcttttggaa accattcttc aaagacggat tgccattctt ccacggctgt ttctttcctt
    15241 tctaattaca aaaagctggc tactaacata acgttagcaa ccagccagtg tttcttgcta
    15301 aattagtgag ttgttccggc atttccggaa atatcttctt tattttctac tgctgcttca
    15361 actgcataag tcaaagaaga agcaatgtct tctaaagaca tagaaggcgt acccactgga
    15421 cgatcgatca cttgatcggg tgagaatggc acgtggatga acccacctcg aattgccggg
    15481 aattgtgttt cgatcaaatg aagcaaacga tacatgatat cattgcagac aaatgttcct
    15541 gctgtataag agatgtacgc tggtagacca tgatcttgta cattttttgt cattgctttg
    15601 attggcaatg aggtaaagta agcggctgga ccgttttctt ctaaagccgt atcgaatggc
    15661 tgatttcctt cattatcagg gattcttgct tctgctagat tgattgcgac acgttcgaac
    15721 gagactgctg accgcccacc tgcttgtccg acacagatca cgacatctgg ttggtgctgt
    15781 tggatggctt ctttgactac ttgactgctt ttttcgaata cggtcggtac ttccactttg
    15841 atgatttcag caccgctgat ttcatctggc atttttttta ctgcttcata ggctggattc
    15901 actttgtccc caccaaatgg atcaaaacct gttactagta ctttcatctg ttgttcctcc
    15961 gtccgattga tttaacatat ggttatcttt tatcatacca ttttccttga acagcgtaaa
    16021 taaaggaaac aatagtttaa ataacataac agatcaaact taatatattc ttataaaaaa
    16081 atagtgttcc actacaatgt tagaagaggt tgcgacaatt attctgtcac aacccctctc
    16141 ttctattatt taaatagaat catataagca atttggaaaa ctagcataaa taacgcaata
    16201 aacaactggt ttttgatcac tccgtatttg tctttcatct ccagcatcgc tacaggcacg
    16261 atattgaagt tagcagccat cggtgtcagc agggtcccac aaaaaccgca agtcaatgca
    16321 accattccta ttaacgctgg attcgctcca tgactaaata cgaatggtgc accgatccca
    16381 accgtcatca cggtgatggc cgcaaatgca ttccccatga ttaccgtaaa tatcaccatg
    16441 ccaagagcgt aaatgatgat gccgatgttc acatttcctt ctggaacgat cgtacctact
    16501 gcattggaaa tcactgtccc aactccagcg cttgtaaata ccgcacctag agaagctaaa
    16561 agcattggca acatgcttaa cggccctact gtgcccagca tatctgctgc atcatctaaa
    16621 aatgtacttg gtcgattatc tcgagaaaag aacatcaaga ttagcatggc tgcaaaaaca
    16681 ccgacgccca cgccgactaa agcacctaaa ttggtaaata gagcaaacaa gatcgcaaag
    16741 acaccgatac tcaaagctgg aataaaaatt ttcattccta gtttgtctga cattttttcc
    16801 atatattctt ttgatggaag ccggctttct cctttgctga ctttcttagc aattgctggt
    16861 atggtcatcg caaagatcaa gccaccgttc acgattgccg gaagccatct tcctcctgca
    16921 ataactaccc ctaagaccgt ccagaaaaag gctgacccat aacgatgagg attggtttta
    16981 tctgttaaat ttcttactcc agtgtaaatc aatacgagtc ccatcacgat ataaaggatc
    17041 tccagtaatt tatcgcctaa taaaatatca ggatttgtaa aaaagtccat cttattgccc
    17101 ctttcctgga taatatttct tcgctaattt cttttcttta agatagaagt agacacttgc
    17161 cacaactaaa gccgtgatag ccactggaac ttccactaaa gcaagctgtc ccaatgttac
    17221 gtcatatcct agatctttca gtgttgattg gactagcaac gcccctgctc ctccgatgaa
    17281 tagtacttgg ccaaagaacc agcagacatt ttccatagct gaagccatac cttttagttc
    17341 ttcttcatgc ttaggatgga cttctaaccc ttttgattcg atggtcccca atgccatcgg
    17401 taaaatgatt ggacgaacaa atccagcaac tccaccaaaa ctcacgttaa aagccgcaaa
    17461 gatcattcga aagatcccat aaatatctac aatcatacca gcagatactt tcttgaatcg
    17521 cttgatcaag gaagccgctg attctttcag accatttctt tcaagcgttc ctgttgccaa
    17581 cataatgatg ataaaaatcg ccatcccgcg attgtttaca aaacttgtac ctaaaagttc
    17641 taacattcct tgaatgccaa gaccgccagt caaagctgta acaactaaag caaccattac
    17701 gatcaatatc gagtctaatt taaatgcaaa cccgagaata acaatcaaga cgcctaaaag
    17761 gctaagataa ttttccatat attttcctcc ataaaatgac aatatttttt taattataaa
    17821 gcaaaacaca taaaaaatat agttgttttc tcacgaaata gacactattt ttaaatattt
    17881 ttcgttattt ttttatcaca aaaattatct tacttattgt aaggtaaagc tttttttaat
    17941 ttattgcccg ataatatata gaaataaggt ctagttactg ttttttttaa atgattaata
    18001 aataacaact tctttctatg aaattgcaaa gcattcatct tcttttccgc taacgatata
    18061 tccgtcagtg cttggtacac tttactaaaa agtatgagat tgccgatatc tggataggtg
    18121 tgctatacta cagaaaaaga tatacaatct gccaccgggt aggataaaga ggatgatcat
    18181 tccattaggt ctttgaaggg atgattttcc tctttttgtg tattttttta tagttaagga
    18241 ggaatgtaag tatggcatgg atggaattaa tcatagcagg aattttggaa gtattctggt
    18301 caacgatgat gaaatggagt gatggttttt ctaaaatcaa ttattctttt tacacagtga
    18361 ttggcatgat tgctagtttt tactttttgt caaaggcaat caaaagtttg ccgatgagtc
    18421 tctcttatcc tatctggaca gggattggcg cagttggttc ggtcataatt ggtgtggtct
    18481 tgtttcatga taagctgaat ctttccactt ggttctttgt ggggatgcta ctcatcagta
    18541 tcattggcat caagattact agcggccact agacacttgg aataagtact gatcagaaaa
    18601 aataagcctt tttatttaat attcaatttt tttatgaaaa aataagaaat aagtccaatg
    18661 acctagcgac ttctccactc atcaggtgta tgcttgtact atctatagaa aaggagtgaa
    18721 tatttttgaa aagtctttcg gtccaagaat tatccaagaa ctttggtcac aaacaagccc
    18781 tcagcgatgt cagttttagc ttatcccctg gcaaaatcgt tggattagta ggtcctaatg
    18841 gcgctggaaa aacaacgatc atgaaagcta ttttaggact gatccattac tcagatggaa
    18901 caatctgtat tggtgaaaat gagatttctc cctctagtca taaagggttg gaacaagtag
    18961 gagcattgat cgaatacccg ggtatctatc cattcttaac aggctatgat catctgaagt
    19021 tattctctga aaccaacgat gtatctgcta tcgacactat cgtgaatcag ctcaagatgg
    19081 aaaagtacat tcacaaaaaa gcgaaatcct actcgttggg aatgaaacaa aaattgggaa
    19141 ttgctcttgc cttactgaac catccgtcta tcgttatttt agatgagccg atgaacggtt
    19201 tggatccaca agcaacaaga gatgtgcgaa aaatcattac cgacttggct actcagggca
    19261 cctctttctt gatctccagt cacttactca gcgagcttga aaaaatggtc gatgagctga
    19321 tcctgatcaa tcaaggaaag atcatcaaac aatgtacaat ggctgaattg aaccaaacag
    19381 cgcaagattt catcgttatc tctacaacaa atgatctagc tgctcgaacg atcttgacag
    19441 aagctggata tactttggaa gatcctgata aaatcaagct tttaaaagaa aacgaagaat
    19501 tattaggaac cgtgatccag ctattgtctg cacaaaatat ccatgtgaca gacgtccagc
    19561 atctgacgaa tgatttggaa tcttctctat tggaaattct ggattcagta aagggggaag
    19621 aagaaaaatg acattgcttg taaaacaaga attatttaaa ttgatcaaga aaaagtcaac
    19681 tgctgtttta tctgttctat tagttgtttt gctcatagga acagcacttc tagccaaaaa
    19741 atacacgacg atcattgatc cagttgaaat gactgctcag ctttttagtg ccacatcttg
    19801 gattgtcttt atcatgattg cagctgcaag cacgatcatt tcgatggaag cacaatatgg
    19861 tacattgaaa aatctccttt atcgaaagta ttctcgagga gaaatattag taagcaaatg
    19921 gatcacatta gttatttatt ctgtttattt atacctttta gctattattg tcactgtgtt
    19981 gatgaaactg attcttttcc cttcgatttc cttcacggag aaggtttcta ctggtcaaac
    20041 actgatccaa agcttgttca cttatacttt gggtagttat atcggtttat ggctgatttt
    20101 aagtttagtg ttgatgattg cttgctttat caatagttcc ggcgcatcca tctcagcagg
    20161 aatcgtcttt tattttgctt cgtcaatcat atctggtatc cttattgcac tcatccaaaa
    20221 atgggagtgg atcaaatgga atccgatcag tatgttgaat ctgcaaaacc aaattggaaa
    20281 cgaagagatc atgaagcaat tgactcatct ttctactaat caaatgctat tcggtaattt
    20341 agcttacatc gttttgttct tagcattagg atatctcgta tttaagcgaa aaaatgtatg
    20401 atgactcatc aaaaaagagg ctgtgaaaga gacgttcagc cttattgccg attggctgtc
    20461 tcttaaacac cgtttattct gaaaaaggag ctgtgacaac atttgtgtca cagctccttt
    20521 cctagtatgt ttttgaataa acgacaggct cacaacctct ctttatactt cttttatact
    20581 tctatacgtg aagcatccca gtggcaaata aaaccattgc aatcactccg accatcgtca
    20641 cacctataag taaaatctta tctaagtgga tatgttgtac aggctcgttt tgctccttac
    20701 gtgctttgag gtaaaaataa atgcctggca agaaaagaac aagaacaagc attacttcat
    20761 taaaggctac gactagcata gcccatactt gaaaggcact tgctaaaagc cctactaaaa
    20821 attggaccca ttctttccgc tgataagaaa gtttcatttg gtacaatcct aagaaaagcc
    20881 acgtgaagaa aatagctgct gtaccaagtg tgtaagcaaa gttataagca ctgtcagtga
    20941 ataataatga aagtaaaaag acattcgtac ataacgtcgt caatacgata gcataagttg
    21001 gtgccccatt tttgttgagt tttccccatg ctttaggcaa aagtccgtct tcagccatgt
    21061 ttcccattgt ttcaatcggt aagatcgtcc atgagagcca aacaccaact aaagaaatga
    21121 tcaaaccgcc gttgatcacg actgctcccc atttaccaac catcatttca aacacatagc
    21181 ccatagcagg ctgcgccttg atcgtttgca gctgattcat cgtcattgtc ccatatggaa
    21241 gcatggaaac caagacgtaa ataataatca agccgaatat ccctagaatc gttgctttcc
    21301 caacatctga ttgttttttt gctcgtgaac ctacgacaga ggctccttca ataccaacaa
    21361 atacccaaag catcaccatg atgcaactca atacttgact ggaaaacggg atcggctgtc
    21421 cattcgcatt caatataatg tcgctagaaa agttatcaat gaattgttgg atcgaaaacg
    21481 tgctgatagc tactacaata aataaaaata atggcactaa tttacagaat gtgacgatag
    21541 cattgacgaa actagcattt tcgactcccc gattcactag ccatgcatat ccccataaaa
    21601 agactgtact catcacgatc gatgccagat tttgcccacc ttcaaatact gggaagaaat
    21661 atcctaatgc gctcatcaac aatgttgcaa aagctacgtt gcctaaccag catgtgagcc
    21721 agtaacccca accgctgata aaaccagcga aacggccaaa accttcttct gcgtaactaa
    21781 agatcccgcc ttttaaatct ggacgttttt tattgatatt attgatcgac aaggagagca
    21841 tcaacattgc tgttcctacg agtacccaac tgaaaatagc tgggccgcca gccgatccgg
    21901 agatgtccgt cataatacca aatacgccac ctccaatcgc tgaaccaatt actaaggcag
    21961 caagtggaat taaaccaatt ccttttttct gttgctctgt atccatgtaa gcatcctcca
    22021 aaataaaacc gcttttatca aaaagtataa caaacctttt ttatttttac ttaattaata
    22081 aaaactttaa tagaaatata attctaccgg cttttttctc attatacaag caaagcgcct
    22141 agtccctttc caaattacac caccaaaaaa cttaaaaaag atgctatact aaaaggaaag
    22201 aattggagga tgatccatga acattttata tatatcgatt tcaggaaata cgcgtgcctt
    22261 tgccaaacat ctagcagaat atgctgaaaa aatgcatgca gaagatcctg tcaatcctga
    22321 agttacttta aaagaaatcc atgaaaatag tgattttacg aaagaaacag aaccattttt
    22381 tactttcgtt cctacttatt tagacggcgg aaatggttta gataacggtg atacagaaat
    22441 cttgaccgaa acgatgcgtg aatatctgga acatgaagac aatcataaac tttgtcttgg
    22501 tgtagtcggt agcggaaata aaaacttcaa taatcagtat tgtctaacag ccaaacaata
    22561 tgcacaaaca tttggctttc ctttcttggc agattatgaa ttacggggaa caccatctga
    22621 tgtgacacga atttatcaga ttttagcaga aaacaataaa taataaaaaa gaagaagctg
    22681 aaaaatagat ttcagtttct tctttcgttt ctattgtttc tatcatatta agctttgaca
    22741 tccatcacag gtgcttttgc ttttgcttta cctgtttttt ccaagacaaa gttttttaca
    22801 cgatccatat tggttaccaa gacgatcatg gatgtttctt tgcctgctgc tttgatcgct
    22861 tctaagtcag cttctgctac aagcgtatca ggtgtcactt gctgcccttc tgttactttc
    22921 acatcaaatg gcgtaccgcc taagtcaact gtgttgattc ccatatgaag caagatttct
    22981 aaaccatttg gcgttgtgat cccaatagcg tgtttcgttg ggaagacaga gctgactacc
    23041 ccagtaactg gagaatagat atgtccgttt tctggttcta caaagtagcc ttcacccatc
    23101 atcttttgtg caaaaactgg atcacttgct ttatctaaag aaacaactgt tccgtcagca
    23161 actgatgaga ggatagtcac actttcagct gaagtttgag gtactacttt ttcaggcact
    23221 tcatttactg tggctgtttc agtcgctaat tcttcttttt ctaaacggtc tttaggaata
    23281 ccgaagaaga atgtagcaac gaagccacca gcataagctg ccaataatcc aaggatgtag
    23341 cctaaccatt taccgtcaga gatcaatggg atcaaagcgg ctcctgaagg tccaatagcg
    23401 atagccccga catttccgat cattccgatc actgccccgc cgatacctcc accgatacaa
    23461 gcagtaataa atgggcgtcc tagaggtaat gttactccgt aaatcaatgg ttcgccgatt
    23521 cctaggatcc cgactggtaa agctcctttg atcatttctg ttaattcttt atcttttttg
    23581 cagcgaatcc ataatgccaa tgctgcaccc acttgtcctg caccagccat cgcaagaatt
    23641 ggaagcaata gcgtacgacc agtttcatca atcatttgca catggattgg agtcaaaatt
    23701 tgatgcagtc cgaacataac catcggcaag aataatgtgc ctagaacgaa gccggcaaat
    23761 gctccaccaa cgccaagtac ccagttgatc ccaccgacca tgccatcaga aatgaaacct
    23821 gctaaaggca tgatgaagaa aatttcaatc agaccgatgg caatcaatga aagagttggt
    23881 gtaacgatga tatctaccgc atcaggtact actttatgca gttttttctc aacgattgac
    23941 aatagccaaa cagcgaagat gacacctagg atcccacctt gtccagctgc aagagcttca
    24001 ccagtaaata agtttttcag tggtgcttcc ggattcatcc ctgtcagcat cacaacggcc
    24061 ccgataactc caccaagagt tggtgttgca ccaaaaactt gtgcagcatt gatacctgta
    24121 tagataacta ggtagctaaa catcccgttt ttcaagatgt tcatcacatc gatatattgt
    24181 tgccatgttg ctgcatcaag tgttccggct gtgactaagt ttgctaaaac tgcggcaatc
    24241 cctgccacga tcccagtacc gacaaatgca ggaatcattg gcacaaagat attagaaatg
    24301 tcttttaata ccgatttgat tttagatggt ttttgtttcg atttttgtgc cgctttcatt
    24361 tcttgtgccc gttcgtttac acggtctttt ccagatgctg atgaatttgc tgtagctgta
    24421 cttacagaag aaagtttttc tcctaatttc acgcctgcca aatcaaccat ttgctgtgct
    24481 actttgttca ctttcccagg tccgatgatg acttgaagct gttcatcttc tactacacca
    24541 agcactcctg gaatcgcttt taattcagag acatttacaa gatcatcatt gatgatcttc
    24601 atacgcacac gagtcatgca gtggacaatg ctttctacat tgcccatgcc gcctgcccct
    24661 ttataaattt gttttgccag ttcttccaaa gtcagttcgt tttttgccat ggtcttttcc
    24721 ccctcataag gtccctttta caaatccgtt tgcttcagct aattttgctt gagcttcctc
    24781 tttatcacta tttgtcaaaa tcatgacgat agccagctta acattttgat ctgcttcttc
    24841 aaagtacttt tcagctgttt cgtaatcagc ttctgtcgct tgcatgatga ttcgttttga
    24901 gcgttcgatt agtttttcat ttgttggttt gacatcgacc atcaagttat tgaatacttt
    24961 acctatacca atcatactga tagtagaaat catattcaag ataagttttt gtgctgttcc
    25021 tgacttcaat cgagtagagc ctgtcaaaaa ttctggacct gcatcgactt cgattgggaa
    25081 atccgcgtgt ttactgattt cggcttgttt attgcaagaa atcgttcctg tgacagcacc
    25141 gatcgatttt gcgtaatcta atccaccgat cacatatggt gtacgaccgc tagctgcgat
    25201 accaataact atatcatttt ttgtcaaatt cagcttgatt agatcttctt gccctagctc
    25261 ataagaatct tcggcccctt cgacagctac agtcattgct tcttctccac cagcaattag
    25321 acctatgacc atttccggtt ctacaccgaa tgtcggtacg cattcagcag catctaacac
    25381 acctagtctt ccacttgttc cggctcccat ataaatcaga cgtccacctt ttttaaagga
    25441 ctcaatcgtg ttagcaatca ctggttcgat acttgtcagt tctttttcaa ccgcagcggc
    25501 cactttctga tcttctttgt tcattagttg aacggcttga gaaatactca tctcatctaa
    25561 tccaaaagtt tcttggtttc tgcgttccgt tgttaggttc tctaaattga ttttgctcat
    25621 ttttatcttc cttcttttct tataaattga tagttcatac cagctttgat ttggttgatc
    25681 aatggtagct cttctttgat aactttagct actacattca ctttttcatc cgctggcaaa
    25741 tcatatttgg ttaattggat ctcacccata tagcgcaaat acttttcgtt atctaaagta
    25801 atagaccctt tcatacgcgt agctgtattt cttgctggga taggcggaat ctctcgaaaa
    25861 cgtgcatcta cgcttcgtat gacatctctt gcatcgtctt gccgattcgt atgcttccct
    25921 aatatatatt cgtaaaattc ttcatctaca ggttccgtat ggagcaagac tgtctgttct
    25981 ttttggaaag aagcaaattg ctcctgaacg ttttctgaca gacctgcatc tccgatgtaa
    26041 acaatatccg tgttacttgc taatagatct agagcgcctg caagaggatg gatccctcga
    26101 tgttcttcca aagttggcaa tccttgatat agtgggcctc tcaactctgt atctcctggt
    26161 acaaaacctt ggacaaggag accttgaatt ttgagccatt gatttttttt ctgataccat
    26221 tctttgtcca gccctgtttc gggacgtgga taataattat gccaagcttc aatctgtgag
    26281 aaatcagctt ctgcttcttt caattcatcg atatctttag gcgtgatcgt gctagcattc
    26341 aaactgattt tcaattgatg tgaccagtcg gcaatctgct gattggaaat atgataatcc
    26401 attcttaaac ctgttacacc aattgctttc aaaggcgtta gatcttctaa tgaaaaaccc
    26461 gctcgttcca atgcctctcc tgaaatatcg accatcaatt ctagtttatt ctttttcgct
    26521 tcgcttccta gttcgatcaa tcgcttttga tatgccgaaa catcatcttc tggtatatgc
    26581 atggaagtga aaataccgac aaagccattg gatgccattt ggcggatata ctgtttcttc
    26641 tcttctgaca aagaatcgtt cataaatatt gaaaagccaa acatattatc cctctttttc
    26701 tgtatccgtc ttcatttcta tgactagagt atatatctaa agaaacaaaa tttcaatact
    26761 tttatcaaaa taattaaatt tcatttctaa aggttgagtt tatattatca aaagaattgt
    26821 cataacctaa aaaaggcact gctaagcaaa agcagtgcct tgaaatattt tatttaaata
    26881 acacaaaaac ataattactc ataagaaacc aattctgtat tatctaccat gaatgtaaag
    26941 aacccctcat taggcatcgg atgaaaataa gcattgatca ctcttatcaa ggcattatgg
    27001 caaactaaca gatagacatt ttcttcgtct tcgatgcatt ctttcaataa aggaacgatc
    27061 cgtgcataca catctaagac tgactcccca tttgggaatc gtacagcgaa cgctaaacgt
    27121 gctttttgaa agttctcatc tttgcttggc agtccatcat aatccccaaa atccatttct
    27181 accaatcgtt catcaacggt cagcggcaag ctgagacgat cagcaactgc ttgtgctgta
    27241 tctcttgctc gttgaagagg ggaatggatg attttcgtga ttggaacagg caaatctact
    27301 accttttctg ctagtttctg tgcctgcatc tgtccttttt cagtcagcgg cacatctgcc
    27361 cgtccgcaaa ctaatccttg tgcgttccaa gttgtttctc cgtgtctcgt tacataaagc
    27421 atgtgattct ctccttcgtt ggcaaagttc cccttaacca taccttgttg ttcttgagat
    27481 tacaagggtt agattctctc aagagaaata atctcagtag atactttatc caggaaggtt
    27541 tgatcatgtt ccactagtaa catggcaggt ttcacgttca agatcagttg ttctaattgt
    27601 tcttgattga agacatccaa ataattcaat ggttcatccc atgtatatag ttcagctggc
    27661 tgtgataaag atttagccaa ttccactttt ttccgttggc ccatactcat ctgctcgatc
    27721 ttgttatgaa aaacatctct ttccatccca agctttcgga ggttgttcaa aaatgcttgg
    27781 tagtctactt ggtttttctc tgcaaattcc gccaacgttc ctcgattgtc ttcataattt
    27841 tggcttgcat aactaatgct cagatgtttt ggctggtatt tttctcctat aaccttgccg
    27901 ttgaatgccc ccagaagata atggataatg gatgactttc ctgcaccgtt aggacctgaa
    27961 atcgccaccc gctgatgagg ctcgattgta aaatgaattg gctcgaataa cagattttca
    28021 taccctaatt gaagatcttc tacgcttaaa agtcgcttat ggtgagacgc ttggctattc
    28081 atcgtcaaag aatcgatata ttcgatatct tttaatagtt tttctttctc gctgatctgg
    28141 gtctccatcc gattcacgat tgctttggat cgtttcatcg tccgtgcagc atcagcaccc
    28201 actgctcctt tattcactcg tctagattca gtatcgatga atccgacttg tttctttgtt
    28261 ttatctcctt ctcgggaacg agaccattcg gctttttcag ctgctgtttt ctttagccta
    28321 ctgacttctt ttttcaattt ttcattttga gccatttcaa attcatcacg aagttttttc
    28381 tgttcttcat agatagagaa attcccttga taaagttcca gttgactttt ttcgattgct
    28441 aaaacatggt ccactacttc atcgataaat ccccggtcat ggctgaccac gatgaagcct
    28501 tgttttttct ttttcaaata agccgctact tgttttctac cagagatatc caaatgattc
    28561 gttggttcat cgattaacgg gaaatgagtg tcatccacaa ataaaagtgc cagtaggact
    28621 tttgtcttct ctccccccga tagtgtgctg aattctctcc ataagatttc aggatctgtt
    28681 tgcatcaatt ggagctctct ttcgatttcc catatctcaa aatccgtaat atcatttaac
    28741 acgtaatagg ttaaacgttc tttatctttt gtctgttgcg ggaaataggc aaattcttgc
    28801 tgatggatta cttgcccttg ataaggtagt ttgttttgta gaatattcag taaagttgtc
    28861 tttcctcgac cgtttcgtcc gataagtcct agtttccatt gtgtgtcaaa atttagattt
    28921 gcttgttcaa ataataatgt gccttggctg tcgtagccga atgtcagatt ttttatttcg
    28981 attttagaca ttttccatca cctcgtaaaa aaagaccagt cctattttca gaactggcta
    29041 aagaggatgc aagggttgga tacacacaaa aagacccata catcgaaaaa accaagccaa
    29101 tcccgaaaat ctgcacactg cttccttgtc tccacaaggt acagtctgaa tgcagctttc
    29161 atcaatcgac ttaatttttc aatgcacgga tccctcactt tgtcctatat ttgaaattac
    29221 gatagcataa agaaaatgat tttgtcaact acttcgggag gatggtgaaa aatctgctaa
    29281 gtgtctgtcc taagattttt gttttttcta atgtttgcct gtgttccatt gcttcttcta
    29341 aacctattgg acccaaatga atacttaaga caattgggag aaaatcagaa agtccttcta
    29401 gctcttggtc tctacttccg caaatagcga ttattggttt tcgatatttt tttgcaagca
    29461 ctgctacacc gtatggaact tttccgtgga tcgtttgctg atcgatccgc ccttctcctg
    29521 taatgatgac atctgcttgt tcgatctttt tttccaatcc agtgatttgg ctgactaaat
    29581 cgaaaccaga aaccatcttc gctcccaaca aaaaaagggc tccaccaata ccgcctgctg
    29641 ctccacttcc tggaatatca tctaaatcca cctcccagaa atcttttatt tgctgagcaa
    29701 tctttcctgc ttgtttatct aagaaagcta gcgtcgtatc tattcctcct ttttgtcttc
    29761 caaattgcca agcagctcct tgttgacctg tatatggatt ggtaacatct gcagcgataa
    29821 tcaattttac tttagaaaca agaacgtttc ttcgatcaaa atgaagtttt ttagtagata
    29881 ataaaggatt tccttctgtg tacccttcta aagaagcacc caaggattgg agtaatccta
    29941 gaccaccatc gctacacccg cttcctccta aagtgacaat aatttgttct acttcttgaa
    30001 gcagtgcatc tttaataagt tctcctaagg cataactgga agcaagtcgg atagtttgat
    30061 ccgttggttt atcaagtaga tctaacccca atgcttgtgc agattcgatg actgcggtgt
    30121 tttttccttg ccaagttgtc aataaatagc tgatttttcg ctgacggaat aagagatcca
    30181 tcccatcaat ggtacgccat gttcccctga gcgcgtaata gattgcttct gcagtatttt
    30241 ctccgccatc tgcaatcggc acattgattt ttcttccttt acgatcttcc cagccattta
    30301 gaactgcctg atttagttca aatgaagaag cacttccttt aaatgaatca attgccgcca
    30361 aaatatccat ctgtatccct cactttcttc ttaagtaaga cacttttttt catttttttc
    30421 aaacaaaaca atgctatttt cttccatttt tctatatact aaaagggaac tcattgaata
    30481 aaggagagaa aaaacatgaa aatcgcaata gctggggccg gagcaatggg cagccgaatc
    30541 ggattgatgc tacatcaaag cggaaatgag gtcctcttga tcgatcgttg gcctgctcac
    30601 attgaagcca ttcgtacaaa tgggttgatt gctgacttta acggtaaaga agtggtcgca
    30661 aaactgccaa tctattcacc agaagaaatc atcgaaagca acgaacacgt ggacttgatc
    30721 gtagcattaa caaaagccaa tcaattagat gatatgtttt gttcgatcca atccattatt
    30781 actgacaata cttatgtttt gtgtttacta aatggattag gtcatgaaga tgtactggaa
    30841 aaatatgtgc caaagaaaaa tatcttattt gggatcacga tgtggacagc tggtctagct
    30901 ggtcccggaa aagtcacatt gttaggtgat ggagaaatcg aactagagaa cttggaacca
    30961 gaaggcgaag catttacaaa aaaagttgta gaagtctttc aagaagcaaa tttaaatccg
    31021 atctatagcc ataacgttcg ttattccatt tggcgaaaag cttgtgtaaa tggaacattg
    31081 aatggtttat gcacgatttt ggattgtaat attgctgaac taggcgcgca aaaagcggca
    31141 gagagcatgg ttcgaacaat cgtatctgaa tttgcttcta tcgcagcaaa agaaggaatc
    31201 atactagatc aagaagaagt gtaccaacat attgcttcta cttatgatcc tgacaacatc
    31261 gggttgcatt acccatctat gtaccaagac ctgatcaaaa accatcgttt gactgaaatc
    31321 gactacatca atggtgccat ttggcgaaaa ggacaaaaat atgatattgc tacaccatat
    31381 tgtgcctttt tgacccaatt agtccatgca aaagaaggaa tccttggcgc agaataaaag
    31441 gctctctgat gagaatcagc tgaatcagca gctggttctc tttttttaag cccaataaaa
    31501 gatcaaaaag aaaacacaac tctcatgatg ccataagaat tgtgcttgtt tgtttcagta
    31561 cataatctct tcaaaatgta ggttttttat ttgttttcaa cagaggagag gtcatattcg
    31621 tattgctcat aaatagtgga atcgttagtg ataaatcgtt ttgcccaatt ttctgcatca
    31681 taaaattcca atagctctga taggattggc ttaaatggtg tatgcagaaa ttccggtaat
    31741 tcatctaaat cacgttctcg aagcaaaaaa atattttcag gacgataaaa atgataatga
    31801 gcaatcgctt gattatccgt cactagtttc ttttgaaaat acatggattc aaatgtccgc
    31861 aaagtcactc cttgctgacc ctcccgcaac agttccagaa tcccgcgcga ttcccctgtt
    31921 tttttcaggt actcttcata agtaagatat ccaggttgtt cattccctcg atgtggaaga
    31981 atgaaatagt tggtcgtaac atctcttttt ataaattcct gcttatagct ttctgctcgt
    32041 tcttttctcc cattattcgt tgcaccaaaa aatagatccg tctttggttc gctagaagaa
    32101 aaattcatat gtttcgaata aaatgaacta ttatgtttca gcccaagttc ttttgcttcc
    32161 aaaaaatcaa aatgataaat ctcatcgatt gccggttcat cttgtgcctg cttcagcatc
    32221 gcctcgtgtt ctgctttgaa gtgattccaa aaaaataaca caatttttgc attggtaaat
    32281 gggcgcacgc gtcgagccat ctccatatca aatccataat ctaaaaaaac gatcagctga
    32341 taatttgcca actgttgtct agctgattta atgaattccg actgtagtaa atcttttccg
    32401 gaccaaacat ctaaagagcg gatggaaggc aaaaaataaa gtgatttatt ttttgcaact
    32461 agcagtacgt catttttgtt catcttttcc gcctcacttt ctctgtcact ttttcctatg
    32521 atagcctgtt taaatagtaa aaagccagta aaacgtttcc tatatttgta tgaaaattta
    32581 acatttgtat gaaaatatga tgaaataaat cattcttcta ttaaaattcg cctaaaagtt
    32641 ttctgaatag ttgtaattgt ctgaaaattt gttatcatta gtcattgtta aatattgcta
    32701 tttattctta atataaattt tgattgtgaa tttaaaagaa agaggtcatt tatggaagat
    32761 aaaaaattga aaaaacaact tagctccaga catatcacca tgttagcttt aggtggagca
    32821 atcggtgcag gtctatttaa aggaagtggc gaagcgattg ggatcgccgg cccttctgta
    32881 ttgattgctt ttttgattgg tgggctgatt ttatatatcg tgatgaaagg tctgggaaaa
    32941 atcgttttaa gcggtggcga cacgcatcac ggattatctg gtttgatacg cccttatcta
    33001 ggtgctcatt ctgctgattt tactgattgg gtctactggt ctatgtggat tatcaatatc
    33061 atcgctgaag ctgttgcagc tgcttccttt ttgcagttgt ggttcccgca cattccagcc
    33121 tgggtatttg tttttatgtt ggctgtttta actacgatca tcaatcttta ttcggtacgg
    33181 ttattcgcag aaacagaata ttggctggct tttgctaaaa tcagtgtcat tatcttactg
    33241 atcatttttg ctacttatct tgtcggtcag caaatgttgg gcacaggcgt tttccctacc
    33301 cttcagcaat tgactgacca tggtgggttt actcctcatg gtatgaaggg aatcatcagt
    33361 tctttgcttg tagttatcta ttcttacggc ggttctgaac tgattgctat cacggtaagc
    33421 gaagcagatg atcctaaacg tgcgattcct aaagcaatca aaggtgtcat gggaagaatc
    33481 atttcctttt acatcattcc tttgtttttg cttttgattc tttttccttg gaatacttta
    33541 gcaggcacga atgtcagtcc ttttgtgatg gtatttgaaa aaatgaatat cccatttgca
    33601 gcggatatcg tcaattttgt gattgtcctt gctttgttct catctatcaa ttcgggtgtg
    33661 tatgcatctt caagaatttt gttcttccgt ttgaaggatc gaaaaggttc ctctagaaaa
    33721 ctagctgttt taaacaagca tcaagtaccg caacgtgctg ttttattttg taccagtgtt
    33781 ctttatcttg gtgtagctct ttcttatttt gtcggtgaca aattatttgg ctatctggca
    33841 ggttcccttt cgtatacagt attattgatc tggatcatta tcagtgcggc atcctttgta
    33901 ctggcactaa gaaaaggaac attatgggat aaaggaatca gcttttttgc attagctgtc
    33961 ttaggattga ttttccttgg tatcctgttc acgaactcca ttggggtaac tgtattgact
    34021 ggcctgcttt acctgttcat ttatttcagt tatcaaaaaa agaatgatgc gttcgtattg
    34081 acgaatgaat gaaatcgata gaaaatttta ttttatttat gtggaataga tggagctatt
    34141 gaagaaagga gttgtgacaa aagtcttgtt gcaactcctt tttccgaata aacagtctca
    34201 tgacctcttg gtaaacggtg ttcaaaaacc ctctgtgcaa aataattgat tgttctccat
    34261 gctcatgaca tgatagaaga aaggaatgaa aaaaaggagt ttgttttaaa tgaaaaagta
    34321 ttggaagttt ttgttgatga tcggtgtttc aacggtagtt atgtttggta tgatgtactt
    34381 gaatgtctat gcgctcgatc atatcttctt cagtcgtaca cgagtattca tggcgttgat
    34441 gatgggtgca gtcatggcag tcatcatgct gttgttcatg tggaaaatgt atgaaaacaa
    34501 aaagataaat gttatgatct tagccgctag tcttcttgtt tttgccggtt ccttgtttat
    34561 ggtacgaagc caaactactg tcaacgacac agcttggatg aaggccatga ttcctcatca
    34621 ttctatcgct atcctggcaa gtaaacgagc tgatttaaaa gatcctgaag taaaaaaatt
    34681 agcggaagaa atcattcagg cacaagaaga agagatcgac aaaatgaaaa aaatgatcaa
    34741 agaaatggaa tgaccattat ccgtccaaat aaaaaaagag gatgttccag aagttatcag
    34801 cttcaagaaa taagaagaag ctacttctgg aacgccgtga ataaggggtt gtgaaaaagc
    34861 tgccctgcat caagtaataa gaacagccaa acaaaaatag cttctcctat ttttcgtttg
    34921 gttaggctta ttaccgcaga tgcaagcttt tgaacaccgt ttattaagag gttgtaaaat
    34981 cagcgttctg acctgagtat tagagagaca aatggaaaaa tagttcctca tattttgcca
    35041 ttttttgagc taataccgag ggtcagctga ttgaacaccg tttatcgaga ggttgtgaaa
    35101 aagtcgctta gtttcgcgta ttaagaaaaa ttttgtgaaa tggctttcca catttttgta
    35161 taaatttggc ttaataccga gaaactggct tttgaatacc gtttattcgt aaaagggatt
    35221 gtgacaaaag tcttgtcaca atcccttttt atgtttttat tgttctaatt gcgctgtctt
    35281 gcttactgct tcttgcggtt tcacaaattt ttttgagatt ccccaacctg tgaaggcact
    35341 gaccatcgaa aacacaggag aaagcaaact gaaaaatacg aatggcaagt aagtgagtgt
    35401 aggaatacca aatgtacttg ctacgaaact tccggcaatt ccccaaggca ctaagtagtt
    35461 gattactgtt ccaccatctt ctagcgttct acctaataca gttggatcaa atcctgcttt
    35521 ttcataagtt tctttaaatg cattaccagg cagaataaca gataggaatt gttcaccaat
    35581 aaaaatattt actccgatac ttgtcatcaa tgttgtaaaa atcaaatttg gtgtgttcgt
    35641 catctttctt gatactcgtt ccatcacggt tgagatcaag ccaaattcga tcaacaatcc
    35701 acctaatgac aaagttagaa taatcaatga cacagtaggc atcatacttt cgattcctcc
    35761 gcggctaagc agtgaatcga tttgttggtt tccagtattt gaaacaaacc ctgattcgat
    35821 gaccccagcc aacttcgtta aggaagtttg tgggttttga ataaaaatca ttcctactgc
    35881 tacagcgata ttcaacaaaa tcgttaaaat tgccggcacc tttttccatg cacacagtaa
    35941 cattaaaaat aaaggaatca gtgaccagat tgaaatagta aagtttgctt ctagaacatc
    36001 agtcacttca cgaatagatg aaagacttgc ggctttactt gtgtgtccta aaatcatgaa
    36061 taaaaagaaa gaaacaacaa atgccgggac agttgaccac atcatatgct tgatgtgttt
    36121 gaacaaatcg gcatcaacaa tagctgctgc tagatttgtt gattcggata atggagacat
    36181 cttatctcca aaaacggcac ctgaaacaat agctccaaca accagcgctg gatttaagcc
    36241 tagtgttgtc ccaataccga aaaatgcaat cccaatcgtt gacataacag taaaggcact
    36301 ccctacagcg ctacctacga ttgcacacac aacaaataca gaagggacaa accactggac
    36361 actgatcaat ttgaacccaa tgaccattag agttggaatg atccctgctt gtatccatac
    36421 agcaatcaat gaaccgacta aaataaaaat aaagattggg atgattcctg gtttgatgcc
    36481 attgatgatt ccttcgtgca gccaatctgt cgggtatctt tttatcactg catacaacat
    36541 gaccattccg atcgctgcta agatcgtgat attaggtgag acctttaatc cgacaacgcc
    36601 aatcgcaatg cctaaaacaa taaccattaa tacaagtgtt gcttctaaaa aacttggtgt
    36661 tccttttttt cccatgataa tctctccttt tttagttgtt cttatgttct aaaaaagtta
    36721 agatatcgga ttactccgcc gcaattcatc cgcgattcct cctttataaa aataaaaaga
    36781 cctgttttaa actaaggacg aatgactccg cggtaccacc ttaattaaaa acagatctgt
    36841 ttttcacttt caaactttta ttcaaatgta tggactttcc atgtaattcg tcaattaggc
    36901 ttgatcggtt cacagcgacc accgactttc tgaacaaaac acctaaccgc tactgcgtga
    36961 aaagttgact tgtacgaagt ttaccttcca taagatcatt tgtcaatgaa aaagaaaata
    37021 ttttttcatt tttctgaaaa ttatttttat aactttcaca cacaagatta ttttttacta
    37081 gaaagtagcg ccctcttgtt tttttcttgc tactatttct tgatgttctt gcttgattct
    37141 ttctaatagc tttggctctt tcaacagatc aagagctgta ttggcgagta gttctgctgc
    37201 aatcgcaata gaagcaaggc ctttgtcact tttagcagca gctttgaatt cttctgtgtg
    37261 tccggcaata tatgtctcag agattgctac cgtaggctgg attgttggta tgacttggct
    37321 gacatttcct acatcagaag aaccgagact tgttctttgt tccgtttcta tttcttcatc
    37381 tggaacacct gcttcttttg catgctggaa gaataagtca tcaaaagaag gagtaacgat
    37441 gacatcatca actgcatttt ggaacaatcc aaactcaaaa gtcgtgcccg tacttatcgc
    37501 agcacctcgt acgatatttt ccactttttc atatacttta tctaatgttt gccgatttcc
    37561 tgcacgtaaa tagaaacgtc cagcagcgta atctggaatg acgttggcag ctactcctcc
    37621 gtctgtaatg atcccatgga tattgacatc ttttggcaat tgcaagcgta gagcgttgat
    37681 tccattaaac acttggatca atgcttccaa agcatttact cctttttcag gtgctgctgc
    37741 tgcatgggaa gcgacaccgt aaaatttgat gtcgactgga tcattcgcta aagattctgt
    37801 cgttttccca taacgaaaag ctggatggac gcataacgct acatcgacat cctcaaaaaa
    37861 accttctcga acaaagctgc ctttagctga tccgttctcg cccccttctt cccctggggt
    37921 gccatataca cggatttctc caccagtttc atcaatgaat tgcttcacta tgctggcggc
    37981 taatacggag taagtaccaa acaaattatg cccgcatgca tgaccaatac ctggtaaagc
    38041 atcgaattct gccaaaaagg caattgtggg accgggttta ttggaaatat aacgtgcatc
    38101 aaaggctgtt cggtgtccag ctacttcttt ttctacccaa aacctttctt tttctaattg
    38161 tttaatcaac gctgctgagg aataaaactc atagttactt acttcaggat gttcgtggat
    38221 atctagagca agtgcttgat attctggtaa acgatattgg attagatcct tcaattggtt
    38281 tgttgagatt gttgttgtca taaaaaattc ctcctatgct agtcattttt cttattttct
    38341 cccgaatgtt tcccatgcag gcacgcttga tccttttgat gttttctcga ttactttgac
    38401 tgtgtcttct gtttgataag cgtctactat tttttgatac gttttattgt tttcatcttc
    38461 ttttcttgca acgatgatat tcacataagg acgtgcatgg tcatccactg gttctaagaa
    38521 gatggcatca gaagcaggat taaatccagc atctacagct acaccgctat tgatcactga
    38581 aatgtctaca tctgacaaag cacgtgctgt ttgggaagca tctaattcag aaatgtctag
    38641 attttttcta ttctcggtaa tatcagaaac agtgggcgct tgtccttttg ccttatccac
    38701 tttgatcaat ccagcagttt gcaataacag aagagctctg ccgccatttg taacatcatt
    38761 agggattgct acttttgctc cgtctttgat atcagctaca tccttcaaag tgttagaata
    38821 aattcccagc ggtgcattga cagtatttcc gatcgatact aaatcagttc cgtgttcttt
    38881 attgtaattg tctaaaaaga attgatgttg gaaagaattc aaatcaatcg atccatctgc
    38941 taaagccaca tttggttgat tgtaatctgt aaatttcacg tattccaaat taatgttctc
    39001 ctttttcaaa cggtctttca cgttgtccca tacatctgta tcttctccaa taatccctag
    39061 ttttacgata gtttcttttt tgtcagttgt atctgctttt ccttggctac accctgccaa
    39121 ccaaataatt gctacaaatg taatgactac aaaacgaata atttttttca ttttttctcc
    39181 tccactttca atgtgtaatt tttttaatca gttgattact gataaattga cttaaaaaaa
    39241 ctaagattag aatcaataat gtagccacaa tcgttacatc tgtttggaat cgattatacc
    39301 ctctcgatat agcaagattc cctaatccgc ctgcacctac tgctccagcc atggtagtca
    39361 gtccgatcac gttgatgata gtcaacgccg agacccgaat gataccaggc aaaccttcta
    39421 acaaatacac acgtaaaatg ataccgattg gactggttcc catcgcttct gccgcttcga
    39481 tcaccccagg atcaacttct agcagtgcgt tctcgatttg acgagcaaaa aacggaacaa
    39541 ctccaaaaat caatggcact aaagctgctt tcgcaccaat cgtcgttcca actaagaaac
    39601 gagtagtcaa tgctaaaaga gaaagcaaga taatgaaagg gatggaacga atgatattga
    39661 tcagcttatc aagtatttca aatagcagac ggttagctag taatccatta gggcgtgtca
    39721 ctactaacgt cacacctaag atgattccaa tcatcccgcc aatgaatgct gtccaaaaag
    39781 acatatatag tgtttgcttc gtcgcttcga caaattcatc cggaatcaaa taaacattgg
    39841 gcaaatatgt tttaaagaaa tcagtcattt tatcttcctc cttcgatcac tttgatacga
    39901 ctatctaaat cgtttttttg taaaatattt atttttacac cagatttgat caaataatcc
    39961 aatgcttttt tccgctgttt ggtttctcca gctaaagtaa cgatcaaact ccctaacggc
    40021 gtttcttgta ataactctac attgccatat aaaatattcg ctgttacttg atatttgctg
    40081 tacagatgag cgattagagg ttcgttcgtc tgatttccaa tataacttaa ttccactagc
    40141 catttattgg cgatctgatc ggcaaaagca gaatgggcaa tgatcgtttc taatgcttgg
    40201 tcaagatgag tagctgttcg aataaaatct ttggtcaatt cttcttcagg attgctgaag
    40261 atctggatgc tgctaccttt ttcaacgatt cttccatctt ccataaccgc taccttgttg
    40321 cagatttctt tgacaacttg catctcatga gtgatcagga cgattgttaa acctaactgg
    40381 cgattcaatt tttttaacaa tgcaaggatc tgaagggtcg ttttcggatc aagtgcactg
    40441 gttgcttcat cacataataa taccttaggt tcattcgcca aagctcgtgc gattgctact
    40501 cgttgttttt gtccccccga cagttgttta ggataagcag atgctttttc ttccaaaccg
    40561 acaagttcca gtagttcatt cactttttga cgacgttcct gtttcgattt tccagaatac
    40621 tttaaagaaa aatcaacgtt gtcaaaaata gttcggcttt ccattagatt gaaatgctga
    40681 aagatcatac cgatggcctt tctttctttt cgcaattctt tgggagagag ctgactcaga
    40741 ttcgtctgat tgacaatgac ttctcctgct gttggtttct gcagcaaatt catcacacga
    40801 actaacgtac ttttccctgc acctgagtaa ccgacgattc cataaacatc gcctttttca
    40861 atcgttaaat ctacagaatc tactgcctgt atctcttttt ctttttgttt gaaacataca
    40921 gaaacatctc gcaattcaat cattaaaatt cctccttatc taaaaaaagc gtcctcaaga
    40981 aaatgaaaat gtcattttct tgaggacgct tttttgcgtg ttaccacctc atgttcaagc
    41041 tgtgttcaca cacaactcct cttcaagtac gatcatactc tagcaagata tcggtcgcag
    41101 ccgtcatcgc cttacatcta tgctcgggat gaattgctcg atggccattt tccaatagtc
    41161 gttccttgct tcttctcagc taccgaagct ctctgtcaaa ggttcttcta tcgtacttac
    41221 catttcaatg caaataatat tcaaaaaaaa agtcctttta ctaacataaa ctatgtcagt
    41281 aaaaggacga cgtatcgcgg taccaccttt tttcggaagt ttccttccct caagcccaac
    41341 atctcaaaaa gagagattgg cgttcgtttt aacggtcgaa cagttccgaa tttgcctact
    41401 tatcgacaaa ttattctcca aggccatttt cagcttttct tacttgactc ttctcaccag
    41461 ccagagcctc tctgcaaagt ttccaaactt actttccttt tcaacgaaat cgatattttg
    41521 ttgttgggat taatctacat gaggaaaact gaaaagtcaa gtacgaaatt caaattattt
    41581 tttctatatt tatttttctg tttttttatt taacatttca ataacagttc gaagatcttt
    41641 tccttccgca agaagtttca atttttcctt ttcttcgacg gtataatttc ggacaaaact
    41701 ggaatcaggt atcaaaacaa cgcctaatcc tgctcgtgaa gcagctgttg ctcctactaa
    41761 agaatcttcc actgcaaagg ctgaactagc ttctaatcct gttcgttcca aagctgtcag
    41821 ataaggaatc ggtgaaggct tgttctccga cacttcgtct ccgaatgtaa acgtgtccaa
    41881 gtaatcagct aatttaaagt gatccaagat atctgttgct cttttcgtaa cagtggtcgt
    41941 agcaatgcct agtttcatat gacgttcttt taagtctgcc aatatttctt ttgcatatgg
    42001 ttttaagtgg atggctccgc ttgtcagctg ttgataaaaa tattcttcac gcttcgctcg
    42061 gacttcctgt actttttcag ggctacctgc tgctttcact aaaatatcaa aactttgttt
    42121 ccagtttttt ccgccccaag cgtcaacgat ttcttttggg atatggatat caaattgctg
    42181 aaatccccaa agccagccat cacgatacgt tttttctgtg tcaactaaca aaccatctaa
    42241 atcaaatatt gcacctttca tctatacatt aatcctttcc aaaacaatac acatagttta
    42301 gcacgactgg tccaaaaaga acagaagcaa agaaccagcc ttctcgttta taagagttct
    42361 tggaatcgac ggatatagat tttcttcaca gctgtcacaa gcgccagata agcgatgact
    42421 gtagcaaata accataacca gtaattgcca ggaagtggca tcaagcctaa ttcagcacca
    42481 aaacttgtaa aaggaaggac agaaccgaca ataattccta atgtagtgat aacaaacatg
    42541 gcaaatgttg cgttgctttg gataaatggt actttcggtg tacgcagtgc atggagcact
    42601 aaggtttgtg tccatagtga ttcgacaaac catcctgcat ggaataatgc gatgaaaatc
    42661 actcgctgtg aactatccaa tgtatggaaa cttccgccca ctacagcagg acaaataaca
    42721 aaatacatca acaagtaagt agtaatatca aatatcgaac ttgttggacc aaagtaaacc
    42781 atgaattccc caatactaga tgcattccat ttttttggct cgtccaaata ttctttatcc
    42841 atccgatccc atggcaagga aatgcaggaa acatcataga tcagattcaa aaacaaaagt
    42901 tgtaaaggca gcattggtaa aaatggcagg aacgtacttg caatcagcac ggaaaacata
    42961 ttgccaaaat tagaacttgc tgtagccttg atatatttca tgatattccc aaaagtttct
    43021 cgtccagaaa gaaggcctct ttccaaaatc gtcaaatctt tttctaaaag gatcacgtct
    43081 gcagattctt tcgcaatatc cacagctgta tctacagaaa taccgatatc agccactttc
    43141 attgcaggag cgtcattgat accatctcct aaaaatccga cagtatgacc atttttacgt
    43201 aaagctgtcg tcaaacgtgc tttttgctga ggattcaatt ttacgaatac ttcatggtct
    43261 tcagctactt gtgctaattc atgatcactc atttccgaga ttttctcacc ggtaaccaat
    43321 tcattgatct ctagacctac ttgacggcac actgaacgtg taactaattc gttgtcccca
    43381 gtcagaactt ttacagctac accatgttct ttcagagctt tcaacgcttg tttcgttgtt
    43441 tcttttggtg gatcaaggaa agcaagataa ccaatcaaaa ccatgtctga ctcatctttg
    43501 actgaaaatt ctccaacgac gcttggattg gtcttttgtg cgacaccaat cactcgtaag
    43561 ccatcttcat taagtgactg tacttttgca agtacggctt cttttcgttc ttttgttaat
    43621 ggtgtaacag taccgccaag atcaataaat ttagaaatgt tcagcatttc ttcaatcgca
    43681 ccttttgtga tcatttgtgt tttaccagct ggatcagcaa ccacaacact catacgacga
    43741 cgttcaaaat caaaaggaat ttcatccact ttttgataat tgatcttatc tgtatctaaa
    43801 gtttctgttg cttcatcaat gatagccaca tctaacaaat ttttcagccc tgtttgatag
    43861 tagctattta gatacgcatg gcgcaaaaca cgatcatctt catttccttc acaatccata
    43921 tgatattcaa gaatgatttt atcttgtgtc aatgtccccg ttttatccgt acataacaca
    43981 tcgattgcac caaagttctg gatggcattc aaatttttga tcactgttcc ttttttggcc
    44041 atcacacttg ctcctttgac caaattcgtc gtaacgatca ttggaagcat ttcaggtgtt
    44101 agaccaactg ctacagatag tccaaaaaga aaagcttcta gccaatcccc ttttgtaagc
    44161 ccattgatga cgataactgc tggagccatc aatgacataa atttgatcag tagcatggat
    44221 gttttatgga tgcctaattc aaagcttgat tgaattggtt tttcagatag cgtttctgct
    44281 acatgaccaa atagtgtttc atttccaaca gaaacaatga ttccttccgc acttccactg
    44341 atgacattac ttcccataaa gacaagattt tcgtaacttg tttcgctttg ctgatcgtct
    44401 tcacatactt tcgcatgctt ttctactgga tagctttccc ctgtcaatgc tgcttgggaa
    44461 atgaataaat cctttgcgga caataaacgc atatccgctg gtatcatatc ccctgctgaa
    44521 agccgaacaa gatctccaca gacgatttct tccataggaa tctctgtgta ctttccatta
    44581 cgttttacag ctgccgttac tttcacaagt gatttcagtt tttcagccgc ttgattggaa
    44641 cgtacggact gaatcaacgt cattgtcccg ctgacgataa ccatagtgaa gataatggct
    44701 acaccgaaaa gatctttatc tccaggagct gctaatacat attccgtgat gaatgaaata
    44761 attcctaatg cgatcaacac taatgtaaat ggcgtgatgt atgctttcaa tatttctaca
    44821 atgaatggtg tttttttgcc atatgaaatc gcattttcac cgtaattttc tcttgaacgt
    44881 tcgatttgtt cttctgtcaa tccatttgct gatgcatgga atagttcaaa taattcttgt
    44941 ttcgtttttc cagcaaaagc tgcatagatt ttttgtgtat ctttcttttt ttccatctca
    45001 atctctcctt tgtgtccaaa agacagctgt tctcgctgct tttggtcttt agctattcat
    45061 cggatcgata gagaaaaaac tgaaaggggc tgagaacaga tagataatag ccctggcctt
    45121 tcctctagat ccttgttttt cgaatgactg tcatccattt gttctcatct cctttactaa
    45181 gtaattttaa ttcatgactt ccaatcattt ttcgaatagt tatttttcca attagaccac
    45241 ctccttttta tttttcaccg atggggattt gcggcaacaa aaaaacctct cgccaaatac
    45301 tcagcgaaag gtttgaaaaa gcatattaaa aaaagcttct cagatctcat cgttgagttt
    45361 tgacactgta caacgtaaaa agcagatacc tgcttttagc taccttatga aaagccttat
    45421 ctcgacaatt cctgttctac ccattggcgt ctctcgacgt ttttgggcag tagcctatgt
    45481 ttgtatagga gcctcaccta acaaatctta ttcggttttc cttcgttaat ataacaacta
    45541 aaaaagagga tgtcaaatca attttccatg tttttcatac tttttttaaa atacacacgt
    45601 tatattcctg tctcacgcgg ttttatttgt ctcattttcc acctcccgct ataatagaaa
    45661 tatagtagga aacgaggtgc tgttatggaa agaacacttg ttattatcaa gccagacggc
    45721 gtgagacgcc atttagtcgg aagcatcatc caacgttttg aagcaaaggg actggccatt
    45781 gctgaaatga agtttgaaac tatgactcct gaattagcaa aagaacatta tcagcacttg
    45841 actgagcgca gtttttttga tgaactgatc gattacatga cttccggtcc tgtcgtttat
    45901 cttgtgctgg tcggcgagga agtgatcgat atcgtccgta agatggttgg agcaacaaaa
    45961 gctgccgatg ctgttccagg tacgatccga ggagactacg cgctgccggg gactgaaaac
    46021 atcattcacg cttctgattc ccgtgatgct gcggtaaaag agatcgcccg ctttttcccg
    46081 ccattcgata taaacaaacc gtctgaaaaa gcggcgaagt gatacaaatt ctaaactgct
    46141 ggtctagttg ctgggttcag caatggccag cagttttttc tctaaggacc tccgttgatt
    46201 ctttcctaac atatattcga gcactgtgaa gaattcttgg tagtctttcg tcttttcttc
    46261 ccctaaagca gcagaaatca atctttgata ataatctgcc atcaatgttt catagatcac
    46321 tgtacttctt tctttatgtg ctaagctccg tttcatatct tcattcacac tacgtgcctt
    46381 tttcaaccga ccattttcta tataaaacga agtcaggttc attaaaaaag taaagagata
    46441 ctgctcatga ttgttcaact gtgctaatcg tcgcattctt tttttgattt tcaaataatt
    46501 gttctcaatg aaccgatcac tgaatatcca aggaaaatca gctagaatag atagttcaaa
    46561 ttgaccatag tctggtatct gcatcaagta ttcttcaatg attcggcatt cataacgtaa
    46621 aaattcaaat tctgtctcag atacttctgt tttttcgacc atgtgaagat tcaaaaccaa
    46681 ataatacaga tcttctgttt tcttaaaatg cctacggtta ttgctgatct ctttataagg
    46741 atcaaagctg tcttcttgta cccgatctag cattcgtctt tttttcttta actttattgg
    46801 ttcatccagc tggtttcgca tccattcata ttctgcaagt gtcatgttca ttcgctctaa
    46861 aaatgatctc aatgttacaa atgacatttt tttcactgaa tttgtctcaa tcccgactag
    46921 agaagtctta aaacagattc cttccgctaa ttgggactgt gtcaacttct tgttgactcg
    46981 aagtttcttg atcaattcac catcatacat aatagttctc ctttttaatt taaatttttc
    47041 cacattcaat aaatagatac gttaaaaagg aaaaatacac gaaaaaaata aaaaaatgtt
    47101 tttttcataa aaaataccaa ccttcaagca ttagaatgtt gtctaactac tgaaggttgg
    47161 tttgattgtt tattgattat ttttttgctg ttcaacgtct gttcttgtta ctggatataa
    47221 gttggttgtt gttttattac cattttttga aaagacactt gtcgaatgtt cgcctttttg
    47281 cttttcgatt gcttcattac gttccgcttc atttttatag tcatattttt tcggatcaat
    47341 cgtctcaaat ccgtttggca cataaaaccg caagagattt tcctgattca gcttatctga
    47401 aagacttaac gcagtcttga ctttttcctg atctttggag atttcctcat cgattcctgc
    47461 tgctttcgta tcgatgattt ctcctgtctg attattgtaa gcttttcctc ctaggacggt
    47521 gtatttgggt gtcacaaagt tcccatttcg aaaagcaact acttgatcat gctgagaaga
    47581 taataagtct gtaccaaaat gaagataatc tttatcatcg attcccaata gatgtagtaa
    47641 tgtcggcaaa acatcgattt ctccaccgta ttcatgattg actgtccctt tagtataacc
    47701 aggcatatgg atcatcaatg gcactcgttg catctgtgcg ttgtcaaatt catcccatgt
    47761 atctggatct ttaccaagag cgcttgctaa atctttatta tctgtattcg agatcccaaa
    47821 atgatccccg taaatcacaa agattgaatt ttggtaaata ccagattttt tcaaatacgt
    47881 aaaaaattgt tccaatgatt gatccagata atgtgccgtt cgaacataat tatctactgt
    47941 gctattgcca gtattcaaag atggaaagtc gaaattcttg tcatccgtat aataaggcgt
    48001 gtggttggtt acggaaagaa atttcgtgta aaacggctgt tgtagatgct caagatattg
    48061 ggcagattct ctgaataaat ctttatctaa tatcccataa cctaacgttt cgtcggattc
    48121 atcaaaataa gatcgatcaa agaaattgtc ataacctaag tttttatata catgatctct
    48181 attccaaaaa ctagctacat tcccatggaa aacagcgctt gtatagcctt gcttttgtcc
    48241 aaggatcgct ggtgcggctt gaaagacatt gtctgaccca agttctgtga ataatgagcc
    48301 ttgaggtaaa ccaaatgtgc cagtttccaa catattttca gcatcacttg tctttccctg
    48361 tcctacttca tgaaagaaat tgtcaaagct gatcgttgct tgattctgga aaatactatt
    48421 taaaaacggt gtgacttctt gtccgtctac cttcatatta atcaaaaact gctggaaact
    48481 ttctaaatgg agaacgatca catttttccc tttagcgatc ccaaatgttt cgggatttgg
    48541 ctctgcataa tgtttctttg tataatctaa aacttcatca atcccattac tgcttgcatg
    48601 cgcgcgaaca ctgctagtca ttcctgtttt gattccgtca taaatagtat acgcatcgat
    48661 tcctagatat ttgacaatat atgaacggtc aaatgttcgc tgcagcaatt gtggacggtt
    48721 ggcttcgctc agcgctagat ttcctgaaaa aataagccct gaaagacagg taacagcgat
    48781 agccatcggt ttgccgacag ggttgctttt gataggtatt ttcttgacct tcaaccaaac
    48841 cagtagccca atgaacacag cgatatccag ccagtagatg acatcatggg gcttcatcaa
    48901 agaaaaggag cttcctgaca atccttgcga cactttcgaa aagcctaata cagatttgac
    48961 tgtaatgaaa tctgtgaatt cccgataaaa aataatattc aagtacaaca aaagcgtatt
    49021 taaaatatca atgatcaaaa gaatagctaa cgctggcttt ggctttttaa tatacaaaga
    49081 aaggccaaaa aacaataagg tagtcgcaat tgggttgatc cacaagataa agtactggat
    49141 cgtaccttcc acacctaatg aaaaatctgc atagtaggca atgatcgtct tcagccagaa
    49201 aaagaaaaca gctgtcaaaa cgattgctaa acgattttgg cacaattttt taagttgtgt
    49261 cacgtatatc acttctctct attcacattt tttcttattt tgctcctgaa aaatgaaaat
    49321 ttcctaaaaa agttgttatc ttaagatttt tttattcttt ctaaagatta ttccgtccac
    49381 ttttcacagc ataaaaccgc tgcgatgtaa gcgattaaac taatgaagag ataaaagtct
    49441 tgtggtgacc gcttcactcc acggtattca aaagccagtt tctcggtatt cgtacaaaaa
    49501 aagaggctgt gacaaaattc ttgtcgcagc tccttatttc ttgatgcagg acagcttttt
    49561 cacaacttct tccttaaacg gtgttctcct gccaactcct cggccacaag tcacaatatt
    49621 tataaaacat gagaagctgt tttttgaaat tgttccttgt ggctcagagt taaacggcag
    49681 gctcaagacc tcttgataca cggtgttcaa tcagctgacc ctcggtatta gattatgtca
    49741 ggacgctaat tttacaacct cttggtaaac ggtgttcaaa agcttgcatc tgcggtaata
    49801 agcccaacca aacgaaaaat ataaggagct attttttgaa attgctcctt gtggctcaga
    49861 gttaaacggc aggctcaaga cctcttgata cacggtgttc aatcagctga ccttcggtat
    49921 tagctcaaaa aacggcaaaa tatgaggaac tattttgccg tttgtttctc taatactcag
    49981 gtcaaaacgc tgatttcaca acctctgttt ttcattgtcc ataggattga tattgtcctt
    50041 gtgatgactc attcgtaata attgaggctt gattttcttc acttcccgtt atcgtttgtc
    50101 cactgccaga atctgaagga cttgttcctg tcgactcgtt tttttgagaa gagacagttg
    50161 ttttcttgac ttgttcattt gtctttttcc attccgctaa acgatcggcg accacttttt
    50221 tgtctacttt ttcagaataa gcggtgatca cttttccatt tttcaaacgg gctactttgt
    50281 cgccatcatg agtcaaaagc aaaacggtca aatgcttgtc tttaaattga tattgtctga
    50341 gagaaatcgc actaagtacg tcatcgatat taataaattg attttcttct tttccttttg
    50401 gcaaataaat gtccaattcg cctttttcgt aattggcagt tattttatac tccgcccacc
    50461 aataagttga gaattctttt ttgaaattat ctactgattc tttgcttgct acgatttttt
    50521 ctgtttcttt ctgagcaaga tctgctgtca tttttcctga aaatgctgcg gataaaataa
    50581 gcagtaagaa aaaaccgaat aaccaaaaga gaagaaacgg tctttttttc ctcatgcttt
    50641 cctccactcc tatttaattt tgactattct attatataca aaaaatgaaa tagaaagaca
    50701 aaaaagttga aaaagatcgt aaataattga acttcttttt cacaaaatgg taagaatgga
    50761 gaatttcacg catttgctct caactattct ttcttaagcc tcaaatccgt ttttatctga
    50821 tacgtctttg aaccaatgac ccgatttttt gattgttctt tttccatctt gtgctaagtc
    50881 tactgaaata aagccatatc gattcttata tgcattggtc cacgaccagt tatccataca
    50941 tgtccacata tgatagccta aacaattggc accttcttga atggcttgat ggacatattt
    51001 cagatgagat tggacaaatt cgatccgata atcatcgtgg atcatgccat cttctttgat
    51061 aaatcgtgct tcgttttcta cacccatacc gttttcagaa ataaagcagt cgatatttcc
    51121 ataatgatct cgtacattga tcaaaatatc atagattcct tgttcataga tctcccatcc
    51181 gcgataagga ttcattttac gaccaggcat ttcataattg tcgaaataat cctcaggcat
    51241 tggaccgttt ttagtatcga ttggtgtttc ttttgctttt acccggcgtg gctggtaata
    51301 attgatacct aaaagatcta ctgtattttc tttgataacc gtcaaatcct ctgcatggat
    51361 cacaggcatg agatcaagtt cttttactat ctcaatcaat tcacttggaa actcgccttt
    51421 tacagctgga tcaaggaatg aacgattgaa gaacgcatct gctatttgcg ctgctttaac
    51481 atcttcaggg tttgattcgt ctcttggata gcttggtgtc agattcaaga tgataccaat
    51541 aacaccacct tgctccattt catggtaaga tttgatggct aacgctgaag ccaacgcttc
    51601 atgatagcca acttggatcg cttttttcat atctgactct tctggataat gccatcgata
    51661 taaataacct gcttcgactg gaacgattgg ttcattatga gtaaaccatt tttttacttt
    51721 cgaaccaaac aattcaaaac aacttttggc atatttttca taggcttcaa ccgtttctcg
    51781 gttcaaccat ccgccttttt cttgcagata catcggcata tcgaaatgat acagattcac
    51841 aaagggttcg ataccgtttt caatcaactc atcaaaataa cgatgataga aacgaacggc
    51901 ttcttcgttg attgttccag attcatcagg tatcaaacgg ctccattgga tagatgttcg
    51961 aaatgaatta tgcccagtct gtttcatcaa ctgtacatcc tcttgatact tcgtataaac
    52021 ttgcgaggtt ttttcaggtc ctacttgatc aaagaacttt tgcggttctt ttttgtacca
    52081 ataatcaaaa atgttctctc cttttccatc gcctgaaatc cttccttctg tttgtgggcc
    52141 acttgctgca gaaccccacc aaaaatttgc tggaaattga tattttttca tcaaagcacc
    52201 tctttttctt ttttagttcg ttttagttga ttccatgtat gatattttcc atcacaatca
    52261 ctttttcatt ttcttcctct tcttttttga ttcgttttaa cagctgttct gctgctcgtt
    52321 ccccgatttt atctgttggt ggcgtgatcg tgattttcgg aaggatactc agatcgtttt
    52381 tatctaaata atcatagtga ctgaacgcaa tatccttccc gattctgaca ccttcttgat
    52441 tgaaacattc gatggcacca atcgacatat tgtaattgct gacaaaaata gcagttgccc
    52501 ctttttctaa taatgctttt gccccgtaat agccgctttt tctagaatag tctcctgtaa
    52561 agacctctaa ttggatcgat ggatcatttt ggaccgcttc tttggctcct gctaaacgtt
    52621 ctcttgctac gtagtctgtt tgagtggcag caataaatcc gattttttta tgtccttgtt
    52681 caccatgatg agcgatcact tttgctacac tttctcgatc attcactaat attgtatcaa
    52741 tacctgctgg tccttctgga caattcaatg cgataactgg aatactcatt tttgtgagca
    52801 tttcaaatcc agaccactct tcttcggata agaagacaat cagcccatcg atcacatgct
    52861 tcatcaggta ttcaattttt tgttcaattt tttctggctg atcggcaaac ccgcttaata
    52921 ataagctata cccattttct tcagctactc tttcgatccc tgagacaact tccgacccaa
    52981 aacggctgga aatcccgttt atcaaaagtc caatagagaa gcttcgatta ttcttcaacc
    53041 ctttagcaat gatgttttct ttatagtcca acgctgaaat cgcttctgct atttttttca
    53101 tgttcttttc cttcagttgc tgaccattca agtaacggga aactgttccc actgaaacac
    53161 cagccatctt agccacatca cggatcgatg ccatacattc tcactcctgc cagttacatt
    53221 tgatttctct ttcttgttgt tcgattatga tgaccgcatt ctttgcatag tgttgcttgt
    53281 catcaatatc catataacta aagtcttcag tagagcaact tcctctcact attaattata
    53341 cttaaacaag tatttgaacc ggttcatttt taatatagca tttttttaaa agattgcaac
    53401 acttttttaa aacgctttct gaaagtggcg gattttttgc ctttttaaaa ttttattcta
    53461 aaatttactc tatttgtggg tgttttgtgc gtttttctct tccatccgtt tgaagtttta
    53521 cattccaatg gtataatttc tttatcctat caaatggggg aagtattttg aagaaattaa
    53581 tcgtactatt tattttgtct gcgggacttt tgacattgac tggctgtgat ttgtttggcg
    53641 gctctgacca atcctcggac gaaacaaccg attcttctgt cttaaaagcg gaaaaagcag
    53701 ataccaccaa cagtgtatat acgctaaaag tacgtaaaga tatggattta tccgcgggac
    53761 agttgacatt tacagataaa aaaatggaat ggacacgcac gtatcagaca caaggaactg
    53821 attcttctga atcatctgaa gaaaaaacag tgctgacaga tatcaagatc actaccaaag
    53881 atgacgaata tattatttca ggaaaagaaa ataaaaaaga aacaacagtc atatttacaa
    53941 aaatcggtaa ttaccgtttg aaggatgagg atggcaacat ctacagtcta tagtgccgtc
    54001 tgttggatct tcttttgttt ctccccttct tttctgctat agtaaagaag caagatgatt
    54061 gtaaaggaga cgaaatggat gatcgatagt cctgattatt gtacatgtaa taacaacaaa
    54121 aatatccata cagaatttaa tgaccaagga agcttgagca tatgcgacaa ctgtcacaaa
    54181 ctagtcaaag attcatttaa aacatttgaa tcttatcctg ttcaaaatta tgtaaaaagt
    54241 agaagaagat aaacaaatcc aagcaaaact cactatggct gatttttatg aacttcaaac
    54301 tcagcttctt cctttgatca agcttcatca gtaaaacaaa cagtggatca tttcagttta
    54361 caaatcaaag agtaaagatt tatttatttc aaatatttga atataaaata accaaacgat
    54421 agaaaggctt attctacatc acgtagta
//
LOCUS       DAIGSZ010000012        53720 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.012, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000012 DAIGSZ010000000
VERSION     DAIGSZ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.012"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            160..840
                     /locus_tag="NOB31_000737"
     CDS             160..840
                     /locus_tag="NOB31_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI0972973.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="NOB31_000738"
     CDS             930..1964
                     /locus_tag="NOB31_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCI0972974.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="NOB31_000739"
     CDS             1978..2313
                     /locus_tag="NOB31_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972975.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="NOB31_000740"
     CDS             2297..4777
                     /locus_tag="NOB31_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972976.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="NOB31_000741"
     CDS             4833..6392
                     /locus_tag="NOB31_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0972977.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="NOB31_000742"
     CDS             6389..7753
                     /locus_tag="NOB31_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0972978.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="NOB31_000743"
     CDS             7924..8994
                     /locus_tag="NOB31_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0972979.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="NOB31_000744"
     CDS             9009..9677
                     /locus_tag="NOB31_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0972980.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="NOB31_000745"
     CDS             9697..10275
                     /locus_tag="NOB31_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0972981.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="NOB31_000746"
     CDS             10676..11587
                     /locus_tag="NOB31_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCI0972982.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /locus_tag="NOB31_000747"
     CDS             complement(11965..12882)
                     /locus_tag="NOB31_000747"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HCI0972983.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="NOB31_000748"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="NOB31_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HCI0972984.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="NOB31_000749"
     CDS             13579..14127
                     /locus_tag="NOB31_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HCI0972985.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="NOB31_000750"
     CDS             14242..16602
                     /locus_tag="NOB31_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HCI0972986.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="NOB31_000751"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="NOB31_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HCI0972987.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="NOB31_000752"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="NOB31_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HCI0972988.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="NOB31_000753"
     CDS             19108..20007
                     /locus_tag="NOB31_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0972989.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="NOB31_000754"
     CDS             20000..21262
                     /locus_tag="NOB31_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0972990.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="NOB31_000755"
     CDS             21423..23321
                     /locus_tag="NOB31_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HCI0972991.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24369)
                     /locus_tag="NOB31_000756"
                     /pseudo
     CDS             complement(23651..24369)
                     /locus_tag="NOB31_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
     gene            24706..25038
                     /locus_tag="NOB31_000757"
     CDS             24706..25038
                     /locus_tag="NOB31_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0972992.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25025..27028
                     /locus_tag="NOB31_000758"
     CDS             25025..27028
                     /locus_tag="NOB31_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HCI0972993.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27047..27517
                     /locus_tag="NOB31_000759"
     CDS             27047..27517
                     /locus_tag="NOB31_000759"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HCI0972994.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27538..28122
                     /locus_tag="NOB31_000760"
     CDS             27538..28122
                     /locus_tag="NOB31_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HCI0972995.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28137..29123
                     /locus_tag="NOB31_000761"
     CDS             28137..29123
                     /locus_tag="NOB31_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HCI0972996.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29113..29424
                     /locus_tag="NOB31_000762"
     CDS             29113..29424
                     /locus_tag="NOB31_000762"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HCI0972997.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29446..31227
                     /locus_tag="NOB31_000763"
     CDS             29446..31227
                     /locus_tag="NOB31_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HCI0972998.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31220..32596
                     /locus_tag="NOB31_000764"
     CDS             31220..32596
                     /locus_tag="NOB31_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HCI0972999.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32603..33238
                     /locus_tag="NOB31_000765"
     CDS             32603..33238
                     /locus_tag="NOB31_000765"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HCI0973000.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33268..34623
                     /locus_tag="NOB31_000766"
     CDS             33268..34623
                     /locus_tag="NOB31_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HCI0973001.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34815..36209)
                     /locus_tag="NOB31_000767"
     CDS             complement(34815..36209)
                     /locus_tag="NOB31_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCI0973002.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36301..37272
                     /locus_tag="NOB31_000768"
     CDS             36301..37272
                     /locus_tag="NOB31_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HCI0973003.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37269..38051
                     /locus_tag="NOB31_000769"
     CDS             37269..38051
                     /locus_tag="NOB31_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HCI0973004.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38220..38591)
                     /locus_tag="NOB31_000770"
     CDS             complement(38220..38591)
                     /locus_tag="NOB31_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0973005.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38725..39168
                     /locus_tag="NOB31_000771"
     CDS             38725..39168
                     /locus_tag="NOB31_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HCI0973006.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39211..40020)
                     /gene="yidA"
                     /locus_tag="NOB31_000772"
     CDS             complement(39211..40020)
                     /gene="yidA"
                     /locus_tag="NOB31_000772"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HCI0973007.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40039..41406)
                     /locus_tag="NOB31_000773"
     CDS             complement(40039..41406)
                     /locus_tag="NOB31_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0973008.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41390..42220)
                     /locus_tag="NOB31_000774"
     CDS             complement(41390..42220)
                     /locus_tag="NOB31_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HCI0973009.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42383..42820
                     /locus_tag="NOB31_000775"
     CDS             42383..42820
                     /locus_tag="NOB31_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HCI0973010.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42896..43516
                     /locus_tag="NOB31_000776"
     CDS             42896..43516
                     /locus_tag="NOB31_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HCI0973011.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43705..44211
                     /locus_tag="NOB31_000777"
     CDS             43705..44211
                     /locus_tag="NOB31_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HCI0973012.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44228..45127
                     /locus_tag="NOB31_000778"
     CDS             44228..45127
                     /locus_tag="NOB31_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HCI0973013.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45214..46098
                     /locus_tag="NOB31_000779"
     CDS             45214..46098
                     /locus_tag="NOB31_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCI0973014.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(46290..46361)
                     /locus_tag="NOB31_000780"
     tRNA            complement(46290..46361)
                     /locus_tag="NOB31_000780"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46326..46328),aa:Arg,seq:ccg)
     gene            46421..47755
                     /gene="rpoN"
                     /locus_tag="NOB31_000781"
     CDS             46421..47755
                     /gene="rpoN"
                     /locus_tag="NOB31_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HCI0973015.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            47904..48995
                     /locus_tag="NOB31_000782"
     CDS             47904..48995
                     /locus_tag="NOB31_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HCI0973016.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            49036..50037
                     /gene="gap"
                     /locus_tag="NOB31_000783"
     CDS             49036..50037
                     /gene="gap"
                     /locus_tag="NOB31_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCI0973017.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            50147..51337
                     /locus_tag="NOB31_000784"
     CDS             50147..51337
                     /locus_tag="NOB31_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HCI0973018.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            51441..52196
                     /locus_tag="NOB31_000785"
     CDS             51441..52196
                     /locus_tag="NOB31_000785"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCI0973019.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            52312..53610
                     /gene="eno"
                     /locus_tag="NOB31_000786"
     CDS             52312..53610
                     /gene="eno"
                     /locus_tag="NOB31_000786"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HCI0973020.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        17826 a         9357 c        11351 g        15186 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaattcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gttccgttag
    24121 ctttggatga ggatcttcca tgtaaagttg tggactgaca tcttgaccac ctgcaagaat
    24181 aagtttgtcg atttgtccaa tcagttgagg agctgaatct ggagacatga ctggcagaat
    24241 aagaggcaat ccttgagcat ctaaaactgc atccacgaat ccttgcggtg tatagctcac
    24301 ttgatttcct tggaaagtat ctgttgctcg aatcagttga tttccggcaa tgccgatgat
    24361 tggtttcatt tgtattcccc ctaaagtaga cttattgtaa caaggattta aaaaaaatta
    24421 aactatgtaa gacttgcccc tatacttatc tgttcttgct gtgttactat ctgtaaagag
    24481 aaatttcgtg tgaaattcat gacgatagtt gaaaatattg cttaatttgt tataataaaa
    24541 agtaagcaga aataaaaagg ttgggcgtaa gcttcaagga tctagttctt caaggggtga
    24601 gaaggacatt ttattgaagg ggcctgccta tactaagtta tctttagagg tacatacttt
    24661 caatgaaaaa agaaagcatg tacctctttt ttaaatcgaa aggaagtgaa gcaagtgtta
    24721 gaagctttgg aacaaatccg aaaagcagaa gaagaaaatg aaaagcgtgc tcaaacactg
    24781 cggcagcagc tgaagatcta tgcaacagaa aaagagcagg aattggaaac gatccaaaca
    24841 aactatcgac aacaactaaa acagttggtg gaagaaaaag aacaatttga aatacaagaa
    24901 ttagaaaaag aaaaaatgaa attgaaagca gaagcagaca aggtgcaagc aactttgaaa
    24961 gatcaatatc aaaagcatca gagtcaagcg atcggtgcga tcattgaaag ggtgaaagaa
    25021 acttatggcc gtcactaaga tggaaaaagt gaccctcatt tcagataaaa gaaatcagga
    25081 gaggatttta caagcagtac aaggaatcca aaacgttgaa atccgggatc tgtatcaaaa
    25141 tagaacaaac aaccagtggg tggagaagta ttttccagat accacgatta ttgataaaga
    25201 agcaaaatta agcgctttag gtaatcggtt gaaagacatc caagaagcta tccaattcat
    25261 acaacaccac ggcgatagcc gtcaaaagaa actccatttg aaacgtcaag aactttcctt
    25321 acaagatttg gaagccaatt attccgaaga aaatttcata aataaattga aagaagtcct
    25381 tgatttaaaa gaaaagtggg aacaactaac tgaagaacgt gatcgtttag aagaagagga
    25441 agaatggctt cttcattggc aacagctgga tattgctcca agtatgtatg caagtaagac
    25501 gaccattttt gagatgggga ctgtgagtgc agcaaatttt gaaagtttca aggaagaact
    25561 gagtaagctt gatgacgttt atatggaaga aatagattat acgccaaaac aagtttatct
    25621 ttcgtatgtt gctttaaaaa aatcagttgc tgttatagaa gaaattgctg ggaaatacgg
    25681 gttcaataaa gaaacgtatc cttatgaaca aaatcctaaa gaaaaactgc aagagaccaa
    25741 gcagcaatta tccattgttc acgagcagca aaagaagata acgacagcgt taggtcagtg
    25801 cagtggctat atccaagaat ttgaatgggt agaagaagtc acacttgccg ttgcagaacg
    25861 agaaaaaata aaagaacggt ttatccatgc gacttatctg atcgttttgc aaggttgggt
    25921 agatgcagaa gaaaaacaga atttgctgca tgtgttaaac gaaaccgtat cagaagaaga
    25981 tatatacgtc agtttcgaaa caccaaactc agaagagatt cagcaggaag tccctactaa
    26041 attgaaaaac catccgcttg tcgaaccttt tgaattgctg actgaaatgt acagtctgcc
    26101 aaaatatgaa gaagtagatc caacaccttg gatgacacca ttttatcttg tcttcttcgg
    26161 gatgatggtc gcagatgttg gttatggttt gctgatgctc attgggacaa tactagctca
    26221 aaaactactt gttctaccac gcgggatgaa acgtttcgta aaattctttg agattctctc
    26281 gataccatcg atcatctggg gattgatcta cagttcattt ttcggacagt cattaccaaa
    26341 agaactgttt ggcatccgct tgcctttccc aatcctatct acgacggatg acgtcaatac
    26401 gattttgatt ttatccgtga ttttcggtct gatacagatt ttggttggat tatttgtggc
    26461 agcaaaggaa aatatcagga gaaaagatta cttgagtgct gtcagtgatg gatttgcctg
    26521 gcaagggatc ctaattggga tcgttattgc gttggttggt gccatgttga taaaaaatac
    26581 agcatttgtt taccttggcg ctgggctatc gatcattgct gccttatgta tcttgatcgt
    26641 tccgattatc caaacgccgt ctaaagtcaa aggtgctgcc aaaggtgcgt ataatcttta
    26701 cggactgacc ggctatatcg gtgatttagt cagttataca cgtttgatgg cattgggtat
    26761 ttcaggcgga agtattggag cggcattcaa tatgctagtt gctttcatgc cgccagctgc
    26821 tcgattcagt gtagggatcc ttttgatcat cgctttacac gcactgaata tgtttttgac
    26881 actgctaagt gcctatgtcc atggcgcacg attgcagtat gtcgaatttt ttgggaagtt
    26941 ttatacagga ggcggacgtg cctttgatcc gctgaaaacg gcggaaaaat acgtcaacat
    27001 caatcacaag aaaaaaaaca ataaataatt ggaggatttt tatataatga tggattactt
    27061 aattagtcaa aatggtggaa tggtatttgc ggtattagcg atggcaacag cgacgatttt
    27121 ttcagggatc ggttcagcta aaggtgttgg aatgacaggt gaggcagcag cagcattgac
    27181 aacaagtcaa cccgaaaaat tcgggcaggc tctgattctg caattgcttc caggcacgca
    27241 aggtttgtat ggattcgtta ttgccttttt gatttttatc aacttaggaa atgacatgtc
    27301 agttgtacaa ggactgaact ttctaggtgc ttctctgccg attgctttta caggcttgtt
    27361 ttcaggtatt gcccaaggaa aagtcgcagc ggcaggtatt caaattttag cgaaaaaacc
    27421 tgaacatgct acaaaaggaa tcatttttgc tgcgatggtt gaaacatacg cgattttagg
    27481 tttcgttatt tccttcctat tagtgttgaa tgcctaagca taaaggagga aaagcagatg
    27541 aacgccattg aaaaaatcat ctctcagatg aacgaagcag cagagcagga aagagcggcg
    27601 ttagaacaag aagagcgaat gaagatcgat caaaactttg aacaaaaacg tacgcaagtt
    27661 gaaacagaac atcaaaaaca aaaagaaaaa caaatcgaat tactcgaaaa aaaataccgt
    27721 cagctaagga atcgccagca agtagaagta cgacaagaaa atttgaatgc gaagcaggaa
    27781 tttttaagac gattgtttgc agatgcggta actgaaatgg aaaattggga tgaatctgaa
    27841 caaatccagt ttatcaaaaa tgcattgtat tcattacctt tgacaggaaa agtagcattc
    27901 attgctggag aaaaatcagc agcctatctt tctcagacgt tgttggatga atggaacaat
    27961 gaacttccct ttatgatggt tttaagtgat gaaactgttg ctgatcaagc gggttttctg
    28021 ataaacgatc aaggagttca gtataatttt cttttcagca gccttgtaca agatatccaa
    28081 ggaacgatga gttttgagat tgccaatcaa ttattcgaat aaggagggat cagtgtatgg
    28141 aataccacga actaaatccc ttgattcgcg gaagagagct tgaacttttg tccaatgaga
    28201 catttgaacg gatgattcaa acaaattctg tcgaagcact tggtgaaata ttgaaatcca
    28261 cgatttacag tccatatatt tatgacggat atgaatatga cttcgaacag aatcttttaa
    28321 aggagcagag ccgtctattt cgctggttaa aggaatcagc accggagcct gaaatcgttt
    28381 ggatctatac gatgcgttat actttccata atctgaaggt tttgacaaaa gctgagatga
    28441 caaatcaaaa tctggaccat ttgtatatcg acgatggatt ttattcatta gaaaccttga
    28501 aggatgccat tcatacgcaa gtttcaaatg aacttcctga aagcattatg gacagtatac
    28561 gagaagtacg tgattatttt gaagagtcta ccattcttca gggaattgac gtgatttatg
    28621 atcgacagtt tttgacagag cagcgacggc ttgccgataa gctaggatat caagaattgc
    28681 tgacagaagt cattgctttt attgacttga ccaatatcac aacgatggct cgaggaatat
    28741 tgcagaaaag aacatatggg ttcatgacga cggtactttc cagctcggga agtatcgaaa
    28801 aagaagtatt tttgaacttt gtagataaag atatggaaga ttacacgaat tttctattag
    28861 agacagatta tgctgatttt ctgcgccctg tcatccgtga gggaaatatt gatctcgtaa
    28921 agcttgaaca gttgaaagat gattatctaa gttcattgta tcaagaagca caaacccagg
    28981 ctttcggacc actgccacta ctagcctttt tgaacgcaaa agaggtagaa agcaaaaacc
    29041 ttcgtttact ggttatcggc aaaagaagcc atttcgaatc agaaacaatc agaaagcggg
    29101 tgagacaagt ctatgacgca taagatcggt gtagttggcg acaaagattc tgttttgcca
    29161 ttcaaattgt ttggctttga tgttcgttat ggtacaacca agcaaaccgt tcgtcaggca
    29221 attgaagaaa tggcaaagaa tgagtatggc gtgatttatg tcacagagca atgtgcagca
    29281 ttgagcccag aaacgatcga acgttacaag gaacaaatga tacctgctat cgtattgatt
    29341 cccaatcatc aaggatcatt agggataggg ctggaagaaa ttcaaaaaaa cgtagaaaaa
    29401 gcagtaggtc aaaatatctt atagtatgaa aaggagatag aaattttgca aattggaaaa
    29461 atcataaaag tctccggacc tcttgtaatg gctgagaaca tgtctgatgc cagtatccaa
    29521 gacatgtgtc tagtgggaga tctaggagtt atcggagaaa ttatcgagat gcgtggcgat
    29581 gtggcgtcta ttcaagtata tgaagagact tctggaattg gtccaggcga accggttcgc
    29641 tctactggtg aagctttatc tgttgaatta ggaccaggga tcatttcaca aatgtttgac
    29701 ggaatccaac ggccattaga tacctttatg gaaatcacac aaagtaattt cttagggcgc
    29761 ggagttcaat tgcccgcatt ggaccatgag aaaaaatggt ggttcgaacc aacagtagaa
    29821 gccggagaaa cggtgagtgc tggagatgtt atcgggatcg tagaagaaac aaaagttata
    29881 aaacataaaa tcatggtgcc aaatgggata aaaggaacga tcaaaacaat cgaaaaaggt
    29941 tcattcacta ttgatgaaac agtatgtgtc attgaaaccg aaaatggtga caaaaatttg
    30001 acgatgcttc aaaaatggcc agtaagacgt agtcggccaa tcaaagaaaa attaaacccg
    30061 gatgcaccca tgatcactgg acagcgagtg attgatacat tcttcccagt gacaaaagga
    30121 ggagcagcag ctgtacctgg tccttttggt gcagggaaaa cagtcgttca gcatcaaatt
    30181 gcaaaatggg ccgatgtgga catggttgtc tatgtgggat gtggcgagcg tggaaatgag
    30241 atgacggatg ttttaaatga attccctgaa ttgattgacc ctaatacagg agaatcgttg
    30301 atggaacgta cggtattgat tgctaataca tcaaacatgc cagtagcagc tcgagaagct
    30361 tctatctata cgggaatcac aattgcggaa tatttccgtg acatgggtta tgacgttgct
    30421 atcatggcag actccacttc acgatgggca gaagcacttc gtgagatgag cggacgtttg
    30481 gaagaaatgc ctggtgatga aggttatcca gcttatcttg gttcacggct tgcggaatac
    30541 tatgaacgat ctggaagagt cattgcatta ggatcagaag gtcgcgaagg aagtataacc
    30601 gcaatcagtg ctgtatcccc gtctggaggg gatatttcgg aaccagtcac acaaaataca
    30661 ttgcgggtcg taaaagtatt ctggggtctt gattccagtt tagcccaaaa aagacatttt
    30721 ccttcgatcg attggataca aagctattct ctttattcaa cagaagtagg gaagtatatg
    30781 gatcatatcc ttcaagctga ctgggcatcc atggtcaccg agggcatgcg tattttgcag
    30841 gaagaacagc agctgaatga aatcgtgcgt ttggtaggga ttgattccct ttcagataat
    30901 gaccgtctga cattagaagt ggcaaaatcc attcgtgaag attatttgca gcaaaatgct
    30961 tttgatgatg tcgatacatt cacttcaaga gagaaacaat tcaaaatgtt gaagatgatc
    31021 ttgacctttg gtgaagaagg acgccgtgcg ttgtcgttag gtgcttattt aagtgagatc
    31081 atggacggta ccgtatcgat tcgtgaaagg atcggacgaa gcaaatatat cccggaaaca
    31141 gaattagaaa aactagatca aattattggt gaaatcaagc aaacgatgca aacgatcgtt
    31201 tcagaaggag gcatgagcaa tgattaaaga atatcgtacg atcggtgaag tcgtcggtcc
    31261 attgatggcg gttgaaaaag ttgctggtgt caaatatgaa gaattaatcg aagtccgtat
    31321 gcaaaatggc gagattcgtc gtggacaagt attggaagtc caagaagata aagcaatggt
    31381 ccaaatattc gaaggaacaa gtggtatcaa tttacgtgac tcttctgtac gatttttagg
    31441 ccatccttta gaactaggtg tatcggaaga catgatcggt cgagtattcg atggtttggg
    31501 acgaccgaaa gataacggac cagagatcct gcctgaaaag catttggata ttaacggaga
    31561 agtaatcaat ccagtagctc gggattatcc agatgagttt atccaaacag gtatctctgc
    31621 aatcgatcat ttgaatacat tagttcgtgg gcaaaaatta ccagtatttt ctggctctgg
    31681 tcttcctcat aaagaattag ctgctcagat cgcgcgacaa gcaacggtac tcgattcatc
    31741 agatgatttc gccgtagtct ttgctgctat tggaatcact tttgaagaag ctgaattttt
    31801 catggaagat tttcgtcaaa cgggcgcaat cgaccgttct gtcatgttta tgaatttagc
    31861 aaacgaccct gcaatcgaac gtatcgctac tcctcgtatg gctttgactg ctgcagaata
    31921 tcttgcttat gaaaagggaa tgcatgtttt ggttatcatg acagacatga ccaactatgc
    31981 agaggcattg cgagagattt ctgcagcacg gcgagaagtt ccaggaagaa gaggatatcc
    32041 tgggtatctt tacacgaact tagctacttt attcgaacga gcaggaagaa tccgcggact
    32101 aaaaggatcg gttactcaaa ttccgattct aacaatgcca gaagacgata aaactcatcc
    32161 aatccctgac ttgactggtt atattacaga aggacagatc atcttgacta gagagcttta
    32221 caagagtggg attcagccac caattgatgt actcccgtct ctttcgcggt taaaagataa
    32281 gggaactgga cccggaaaga caagagaaga ccatgcagct acgatgaatc agctttttgc
    32341 agcctatgca caaggaaaac aggcaaaaga attagccgta gttttaggtg aatctgcttt
    32401 atctgatgta gacaagatct atgcgaagtt tgctgagcgg tttgaaaaag aatatgtcaa
    32461 tcaaggattc tacacgaacc gttcgattac tgaaacactt gatctagggt gggaactgct
    32521 atcgatgttg ccaagaaccg aattaaaacg aatcaaagac gacatgctgg acaaatatct
    32581 gccagaaggg aagtgagttc tgatggcacg attgaatgtg aatccgaccc gcatggaatt
    32641 gactcgattg aaaaaacagt tgacaactgc cacaagaggg cataaattat taaaagataa
    32701 gcaagatgaa ctgatgcgtc aattcatcct gttgattcga aagaacaacc agctgcgtca
    32761 agaaatggaa gagtctatga cagaagcaat gtctgatttt gtattggcaa atgcttcgat
    32821 cacggaacct ttcatcgaag aattatttgt tttgccggcg gaaaacgttg atttgtctat
    32881 cgtagacaaa aatatcatga gtgtaaaagt acctgtgatg aattttgaat atgatgaaca
    32941 gctgacagac acacctttgg aatacgggta tttgaattcc agtgccgaac tggatcggtc
    33001 aatcgatcgg tttactaccc tgcttccaaa acttttggaa ctgacagaaa tcgaaaaaac
    33061 ttgtcaactg atggcgagtg aaatcgaaaa gacacgtcgg cgagtcaatg cattagaata
    33121 tatgacgatc cctcaattag aagaaacgat ctattatatt cgtatgaagc tggaagaaaa
    33181 cgagcgcgca gaagtaacaa ggttgatcaa agtaaaaaat atgggtacca ctgactaagt
    33241 ggtatctttt tttaaaagag gaaaacgatg attaaacaaa gcaaacaaat aaagaaacgt
    33301 ttgccggctg ttcagcttct cgcattagga ttttttctcc tgattttagt tggcggcggc
    33361 ctacttaccc taccattttt tagtaatagt gggcatggga caaattttat cgatgcgctt
    33421 ttcactgcaa cttctgctgt ctgtgtaacg ggattgacaa cattgaatac agcagagcat
    33481 tggaacagtg ctggtcaatt tttgatcatg cttttgattg agatcggcgg tcttggtttt
    33541 atgatggttc cgattctatg ctttgcattg ataaagaaga aagtcagtct cagcacacgt
    33601 attatattaa aagaagcgct gaatctagaa gaagtatcag gtgtgatgaa gctcatgctt
    33661 tacatcctaa aattggcctt tgtgatccaa ttgattggta cggttgcttt atcttttgta
    33721 tttgtgcctg aatttggctg gttgaaaggt atctggtaca gtttgttcca tgcaatctct
    33781 agtttttgta atgcagggtt tgatttgtta ggagacagtt tagccaatca ccagcaaaat
    33841 gtttatttga tcatggtggt atctgctttg atcatttctg gtgggttagg cttcatcgta
    33901 tggcgtgatt tactggaata tcatcagaaa aagaagatga cgattcattc aaaaatcgca
    33961 ttaaccgtta caggtaccct tttattaggc ggattcgttg tgttcttttt cacagagcgc
    34021 aatggggcaa cgctagtgga agggaatatg tttcaacgat tggcaaacac cttttttatg
    34081 agtgtgacac ctagaacggc tggatattat tcagttgatt acctccatat gagccatgca
    34141 ggtctgattt taacgatgtt tttgatgtac atcggcggaa catctgggtc gacggccggc
    34201 ggattgaaaa caactacgtt aggtgtgttg ctgatccaga tgcgttcgat gttgaaagga
    34261 cgtacgagag cggaagcatt tggccgtacc atccgacaag gcgcagtgtt gcgggcactt
    34321 actttatttt ttgttacgtt gacgttgtgt gtagtcgcca tcatgatttt atcggtgact
    34381 gaaacgatac ctaaaacttc tggcatcgaa tatattgctt ttgaggtctt ctctgcgttt
    34441 ggtacagtag gtcttacgat gggattgacg ccagacttga ctgcaatagg gaaattgatc
    34501 attatagcgc ttatgtacat tggacgagtt ggtgtattga ctgtggtctt ctctctgatg
    34561 acaaaagcac aaagaacaca atcaaaatac aaatatccag aagaaagtgt catgattgga
    34621 taatttcatc ttctgacaga aacctagtga tttagtaaaa taagaaaata aaataatttt
    34681 tcttgcttct tggatacttt aagtgcaaaa tgttcgttta ttttttgagg cactacccgt
    34741 tgttgaacct cgggtagtgc ctctttttta ttgaaaggaa tcaataagat ttgattcctt
    34801 tatttatcaa taggttataa ttcatatttt tttatttttt cttttacgat acttagtcca
    34861 gaagctaaaa tttcaaggtt attagaggat agggaaattc gaacgaatgc atctggttgc
    34921 gcacgtgtag taaagcgtct ggaatgataa agtcggatac cgttagcaag aaagtcattc
    34981 tcaattatct tagggtcaat ctcaggatca actggaagaa ttcgatagta agggacacga
    35041 ttcgttggtt tttctacttt gaaaagagaa tcaaaaagct gattggctct ttttgtaaga
    35101 cttaatttag tttctaagat cctatttgct tcatttgaat ggaggatttg agtgatgact
    35161 tccacatcta atccagaagt tttcacattt atattaaaaa ttgcttgttc tatcttgctt
    35221 tggacatgta ctggaactac aagataagca actcgcaatc cagaacaaat aaattttgtc
    35281 attccagcta agtagattgt ttggttaggt aataaatttt ggaaaggagg aatgatcgta
    35341 tgttgatagt aagttgttaa aaatgaatgg atatcatctt caataaccca tagaccttct
    35401 ttttcaatca cttcggctaa ttgctctcgt cttttgtgag agatttgaaa ccctatagga
    35461 ttattacaag aaggcataag aaagacacca tgaatcttct tttttctaca ttcctgaatc
    35521 aatatatcag gtcgcattcc ttgctcgtca aaatcaattg gaacgatctc taaatgatat
    35581 aactgagcca attcaatgaa attagcgtat gtatatcggt ctgttgctat tctatcacct
    35641 ggagagaaaa gtgcagaaag tgtgatagcc aatccatttt gaacaccgga aacaatagat
    35701 agagattcta aggacggaat gactccttga gtttttaacc aatttgctgc agtagtcaat
    35761 tgaaaatttg tgcctttggg atcttggtaa ttaagcaaac caacaagatt tgggttatta
    35821 ctagttgatt gaataaacgg gacaacgaat ttattacatt cttcaaaaga actaaccaga
    35881 ccaaaatcaa tgatatgttc ggttacttca ttggtagaga tggtgatgga ctcaaagaca
    35941 ttgggagaaa taaatgtgcc acttccaata ttcgtataca gcaaaccttt ctcaattcca
    36001 tatttataag ccttgccaac ggtagtaaaa tttaaatcta aataatcagc tagctctctt
    36061 tgggagggta actgagtgtt tttctgtaat ttattcttta aaatatcttg ttctaattgt
    36121 tgaatcaacg atcgataata aggacgcttc aatttttgtt tgtctggtcg ccaagttaac
    36181 gggtaattgt cataagaatt aataggcatt ttctccactc cttaaaattg tataccatac
    36241 aattttacca ttgattgtat tgattttaga agttaatctt ttgtgaggag ggaattgtct
    36301 atgaaaatta ttaattttga ggaagtagta gcttctttta gttttgaaga agcgattcaa
    36361 gtaatgaaaa aatgtttttt tgattatgaa agtggtaaaa tcagccaaaa tcctcgattg
    36421 gtggaaattt tacctgacgg aaaaggcaaa aatatgtttg cgatgatgcc tgcttatttg
    36481 ggggagaaca gatattttgg cacaaaagtc attaccgctt ttccggataa tcatcagtat
    36541 catttacctt ctcatttagg agagattttc ttgtttgatg ctcaaaacgg actacccaaa
    36601 gcattgataa acgcaaatgc agtcacctgg attcgaacag ctgctgtatc tgcgctggca
    36661 acagattact tagcaaatcc gcatgcagaa acacttgctt taattggagc tggtcaacaa
    36721 gcattgtcgc atttgactgc gatttctacc attcgtccca tcactacagt gtttgtttac
    36781 gatattttag aagaaagacg aaatactttt atcgctaaag ctaaaaaaca gtatcctaaa
    36841 ataacgttta taaatgcaat atcagtagaa gatgcagtac gtccagcgga aatcatttgt
    36901 acgttgacct ctagtaaaga ggcatttctt caaaaagagt gggtaaggga agacgcacat
    36961 atcaatgctg tgggcacatt tactcctgat acaagagaga taagtacatc gttgatggaa
    37021 acttctcaaa tctatgtaga tgattactca gctgccttaa cagaaagcgg ggacctgctt
    37081 atagccatgg cagaaggaga tttagaggaa tcttgtattg ttggtacatt aggcgaatta
    37141 gtttctgaga aaaaaacatt ttataaagga gaatcgaggc cgacgatttt cgacgcagtt
    37201 ggtctagcta ttgaagatct ttgttgtgca gaatatattt ataacaaatt agagaaaggg
    37261 gctttaaaat gaacttagat tattacgtag ttgatgcatt tgcagatgag gtgttcaaag
    37321 gaaatccagc agcggtttat gtgctagaag aatggctgcc agaaggtacg atgcaaaaaa
    37381 ttgccattga aaacaattta tctgaaacag catttacagt gaagaaaaac caagaatttg
    37441 agcttagatg gtttacgcca gatcgagaaa tcgatctttg tggtcacgcg acattagcaa
    37501 cagcatttgt tttatttaac tattacaaaa tacctgatga aacgattaaa ttttctactc
    37561 aaagcggtaa tctatttgtg acaagaatta aagattatta ttacatggat tttcctagta
    37621 ttatgccgaa aaaagtgccg atattgtctg aatatgaaga agcgattggg gctaagatta
    37681 aagaagccta cttagcacgt gatttatttt tcgtattaga agatgaaaaa acggtggcta
    37741 aattgcagcc agattttaca gctatcaaaa attttgaatt aggaatagga gtcatcgtga
    37801 cagcagaaag tgtgcaaaaa gactttgttt ctagaacctt ctttccaaaa ttaacaatca
    37861 atgaagatcc agtatgtgga tcagcacatt ctaatcttat tccttattgg gcagaaagaa
    37921 tgaataaaac aaaattgtca gcttatcaaa tgtcatcaag gggcggggat ctagaatgtg
    37981 aattaaaaga agatcgtgtg ataataggag gaaaagcagt tttgttttct aaaggtacct
    38041 cgtttatttg atttctttca aatgaattaa aaataaattg gtggagagtg gcaaccttat
    38101 agctacaatg gttgttaaaa aaagacgcaa actttttcaa tttaatgaaa agtttgcgtc
    38161 tcattttaat tattggtgtt tgttttttat tcaatcaaga gtaaaatgcc ccatactaac
    38221 tatcctcgga tgacttcgat tttataacca tcagggtcaa tgacaaagta gtaagaaggc
    38281 gcagtgccag gtaatccttt taagtcagta atctcaagac cagcagcttt atgttgctcg
    38341 tgtaattttt ctagatcatc agctgctata gcgatatgac catagccgtc tcctagatca
    38401 tacgcaccat gatcatagtt gtaagtcaac tctaattcat agtcatcccc aggaagtgtc
    38461 aaataaacaa gtgtaaattt gttttctgga aaatcacggc ggcggctttc ttcaaaacca
    38521 aatgcctttt gataaaattc gattgatgct tcaagatctt tcactcgaac acatgtgtga
    38581 gccattttca tagattcatc tctccttttc cttttactca atcataacaa aaagaagtaa
    38641 ggaaatagtt gatttgtgct tgttcatgag aaatttctca tgtaaaatgg atagaaaata
    38701 aaactgttaa ggtggaaact attcatggat aaaccaattt ttggtgaaaa aaagcaattt
    38761 gctgattatc aaacccgtta tgcagcatat attgtcatag aaagagatca gcagattgca
    38821 gtaatcgagg ctccaaatgg tgcttttttt cttcctggcg gggaaattga aggagaagag
    38881 acgaaagaag aagcgattgt ccgtgagctg atagaagaaa tgggaattgt ggcagaaatt
    38941 tcttcttatc tgggagaagc tgatgagtat ttttactcga attatcgtgc aacttattat
    39001 tataatccag gatatttctt tgttgctgat tcttggaagc gtataggaga accaactgaa
    39061 aagaccaata aaatttggtg ggtgagccct caagaagcgc ttgtgaaatt gaaacgtggt
    39121 agccaccgat gggcagtcga gagatggatc gaaaaaaata aaaactgaaa gaaagcgagt
    39181 agatcagctt tctctcagtt tttttattta ttacagtaca tattttttga ttgcttcagc
    39241 tacaccgtgc tcgtcgtttg atgaagtgat gacatttgct gcttctttga caagagaaac
    39301 ggcatttccc attgctactc ctagaccagc atattcaatc atggataagt cgttctcgtt
    39361 atctccgata gccatgattt catcttgatc aataccaagg tgctgtgcga gattcgcaac
    39421 tgccgcacct ttacttgctt ctttatttag tacttcgaag taatagggcg cacttttgac
    39481 cgttgtgtat ttatcacgga aagtttgcgg taaacgcgca attgctgcat ctaaaatttc
    39541 tggttcgtcg atcatcatca ttttgacgat gttcatgtct ggtgtcattt cttcaggtgt
    39601 tcgatatttt agcggcatct tgactaaact tgcttcgtgg atcgtataag cgctgatatc
    39661 tcgattaggc gtgtagatcg ctttgtcatc gatcgaatgg agatgactgc cgacacggcg
    39721 tgccattact tcgatctcta ggaaatcttc atgtgtcagt ccgtgacggg cgatgatttt
    39781 acctgatttc gtttgttgta cgagtgcccc gttataagta ataacgtaat cattatcttg
    39841 aaaaaggttc aactcgttta actgttcctg gacacctggt aagggacggc cagtgcataa
    39901 aacgatcgaa acaccttttg caacagcagc ggcaatcgct tcttttactt cttttgttac
    39961 ttctcttttc tcatttaata aagtaccatc gatgtcgata gcgactagtt tgatagacat
    40021 aatttcctcc aatatatttt aatttatttc aatcaatgcg ccattacgga tatggctggc
    40081 aaattcttga taagtttcgt caaataaatc ataatgatca cgcaaggacg gatcaaccat
    40141 ttcttttgga aagaaaaatc gctcatctcc ttgttcttgt cccgctaatg cagcaacaag
    40201 ctgactaacc tgtgataatt ctatcaaagt tccgtcattt cgcaaaatct cgatttgtgt
    40261 gcgatgtctg ccttgttctg ggcgataaaa atcataaggt agatcgtagc tagaattcac
    40321 agcagtgtaa taaacaggat tatatccgac cttttctact aacaaagtga gttcttggac
    40381 taattttgaa tcccggttgc cagaaaaagt agcagatttc agtggtttac gattcaaaaa
    40441 acgtttagct aaatcattta aaataggatc agcagattca gaccattgag taaagtaagt
    40501 gcccaagacc ccatcatcaa gtttgaggta ttcttctaaa gtaaagcttc cgtcaagaaa
    40561 tggcagaagt aattgagaat ggagttcaaa actgctggca tcttcttgat acaactcgtg
    40621 tgcgcgatga agcagatgct ccaaaattac ttccatacca cgggaaacag gatggaagta
    40681 cacttgcaca tacatttgat atcggctaac gatataatct tccactgcat gcatgccact
    40741 catggaaaaa gcgatcccgc cttcataagg acgaatcaca cgtaatattc gggtaagatc
    40801 aaatgttcca tattctgttc cagtgaaata agcatcccga agcaaatagt ccattcgatc
    40861 tgcatcgatc tgactagaaa tcatttggac aacttgtggg ttggggtaag ttttttggat
    40921 cacactagct accttttcag gaaaaccttc ttctactcgg ttaagaatct gatacacttc
    40981 tgtttctgga gaagtgatga tctctacagt gatggcttca tgattcgtat ggaagatatg
    41041 ttcaaatgta tgagagtaag gaccatgacc gacatcatgc aacagtgccg cacataaagt
    41101 caccagccgt tcctgatcat cccagcctcc gttgcctatt ttttcttttg aaaaatttcg
    41161 agaaaagata tcgcagattc gtcttgaaat ctcataaacg cctaatgaat gagtaaaacg
    41221 gctatgttct gctccgtgaa aagtgaaaga agaagtgcct aattgtttaa tgcgtcgtag
    41281 acgttggact tctttcgaat tgatcaaatc taagattact tgatgctgga catggatata
    41341 gttatggact ggatcacgaa aaactttttc cataggcagc atttgatatt tataaggggt
    41401 tgtcataatg tagctccttt atgttattac gttgttccat tctctggatt tggttgttcc
    41461 attgctccag ctggatttct ttttttagcc agtcggtaga atcctgtaaa tcacttgcag
    41521 aatacagctt ttcaaaagct tttgcaaatg cttctttgac ttcttttaca aaaaggggtt
    41581 ggtcaagcag ttcttcaagt gttgccattg tagcaggatc cactgcagga tagccatttg
    41641 taccaaagtc ttcttttaaa gcagattgat aaaatcgctt catgacttgc ccacgttttt
    41701 cctgattacc gttgacactt aagtacatca taacagaaat cccatttttg atccgacgct
    41761 gagcgatacc ggcaaatttt ttgccatgga tgcttaaatc ataagttcca ggacaataag
    41821 aatgggtgat ttcgaatgct tgtatcggtg cctttggaaa agcgtattta gtcaatagga
    41881 gcatttgctc gtaagcgtca tctatggtta ttttttttgt gtcactttgg gggaaaatca
    41941 aagaaatatt caaaattcct tcatctgata cgatccctaa tccacctgaa tttctgatca
    42001 ctggagcgta acctgcatct tccagtgttt ggatcccgtc acttagaaaa ggagttcgaa
    42061 catccttcat acctaagatg actgtgcagt catattgcca gaaatgtaaa aagatttgct
    42121 ggtgttcttt agaatattcc gttaatatat ctgttaatgc aaaaggggaa aagtcgtttt
    42181 tttgataaat gtgctgatct agtcgaatcg cagggttcat tcaaccggct cctttgtata
    42241 aattcatatt ttctacaata ttatactcta aaatcaaaga gttgttttgg aaaaaaggtt
    42301 ttctgtaaaa atggacaagt tggttgacaa aacaaaagaa actaggaaca atgtagctat
    42361 gagaagtaaa ggagaatgaa taatggaatt atcacaagga acaccgattt caatcaaatt
    42421 gcgtacaaaa gtaaaacagc aaggggaagt gcaagatttt tattttgatt tgaaagggca
    42481 aatggtgaca attggcgata cgctgtacat acgttataaa gagattcagg aggagacggg
    42541 cgatgagatt cctgtaacga tcaaattagt tccagatggt catgtacagc tgatccgtgc
    42601 aggagaaatg cggatgcgtt tgaaatttgg ctataaagaa cggttagaaa catcctatcg
    42661 aacaccatac ggtatgatcc agattgctac ttttacgaaa gaactgcatg ttagtttgaa
    42721 agaccgtccc acagcaggga aggttcgaat cgattatgat ctgttcatgg gaccggaaaa
    42781 aatcggcgaa tattatttga ccttggattt tacagcgtaa atataaaaga aaagtttgat
    42841 tttttgtgtc tgattttgta tgataaggag tagactgtga aaggacgtgt cctgattgga
    42901 aattagtgta tttgaaggtg caaacaaaag cgaattatca atgatcgaag tagcacacgc
    42961 gatcttagaa caacgtggcg atgtcatgga tttttctgat ttagctaacc agatccaaaa
    43021 ctatcttggg aaatcagaca gtgaaattcg tgattcactc gcacaatttt atactgactt
    43081 gaatattgac ggcagcttta tctcattagg ggataatcgt tggggcttgc gttcatggta
    43141 tgctatcgat tcgatcgatg aagaagtaaa ccatggaatg gacgaagagg atgaagatac
    43201 tccacgtcgc cgtaaacgca agaaagtcaa cgcctttatc aatgatgatg aagacgcgat
    43261 cgattacaat gacgatgacc cagaagatac agatctgaca gaagaagatg acgatgatct
    43321 gtttgatgac gatgatgatg aagatgaaga aatcgctgct tataattctg acttgcaaga
    43381 aatcggagca gatgacccga cagatgatga agaagacttg ccaggaaata tcgaagaaga
    43441 tttaagtatc atagacgaag acgatgatga tgaagattat gaagaggaag aattttctga
    43501 ctctgaaaaa gaataaacat tattttctta cgagaggttg tgacagagac gatcagccta
    43561 tcagaataag gaggtgtgac acgatttttg tcacaccttc ttttttgtat ataaaaatcc
    43621 caagtaaata cataaaaaat aaaaaaattg aaacttttag cgcaccttgt acgtcatatt
    43681 aagtgaggca gaaaggagtg gagaatgatt tttactggat ataagaaaaa acggcagatc
    43741 gaaaaatacc gtcacctgct gaatggactc atcgaaactg attatcaaaa aatgttccgt
    43801 atcacgatga attacgtaca tgataaagaa gaggccttag atgtgatgca agatagtttt
    43861 cataaagccc tgaactattt tgaaaaagaa aaagagatcg agcattttag tgcatggttt
    43921 tatcggatat tgatccgcac ggcattagat agttggcgca gacaaaaaag gacgcctgtg
    43981 gacttatttg aaattcaaga tatcccccaa cagttacctt tagaaacttc cgttgcagag
    44041 ctccatatga ttttagataa aatagacagt ccggaaaaag agattctgat cctctacttt
    44101 tttgaaggat ttcgtttgaa agaaattgcg actatcttgg atatgaatga aaacacagtt
    44161 aaaacgaaaa tgtaccgctc attgaatgct ttacgtcaaa tcctagaatg aaggagagaa
    44221 gagtgccatg tattcccaaa aagaaaattt aaaaaaacta aagaaaactt ataaagaaca
    44281 agcaattccc aaagggctta aagaggagat ccgccagcgt tttattatcg aagagcaatc
    44341 atttataaaa gcaaagcgga gaaagagacg tctccaaggg ttcggagtat ctttggctat
    44401 cgtaatgatt acaacaagta gccttctttt taatagtcaa gttcgaagct ttgcagaaga
    44461 tttacccatc ttaggatcag tcattgaatt gatcttaggc gaacgcttta ctgatcgatc
    44521 tgaaaaaatc gatattcagg taccgaagat caatacacaa aatgagaaag aaaataaaac
    44581 aattcatgga ttaaatcaaa aatactttcg cgaaggacaa gcagattttg aaaaagctga
    44641 aaaagaatat ggaaattttg aaacggatca ttaccaagtt ttgggagatt atcagaaaat
    44701 cgtagacgat aaccggtttc tcgtgattga aaggcagatc acccaaacag cagcagatag
    44761 ccatgttgaa aaaagatacg acacaatcga caagaaaaac agtgtccagc tctcacttcc
    44821 acttttattc aaagatgaca cctatctatc tgttttgaca aaagaagtca aacggcagat
    44881 ggccgaacaa gtcaaggaag atccatctaa gtactattgg actgagcaag atattcaaga
    44941 agggacgata gaaaaaccaa cacttgttac gcctacacga agtttttatt tgaacaaaga
    45001 gcatcaatta gttttgactt tttctcaata cgaaattgct cctggttata tgggtacacc
    45061 agaatttgtc attcctaagt ccgtgacaaa aacgattttg gcatcggaag attatttgga
    45121 tcattagacg agaagtagtt gcgactagca gtttcaattt tcaagtaagt acaagtaaat
    45181 aataagaaga gaaaaagaga aagaagagat atagtgaaaa gaaattattt agttatcagt
    45241 attattgctt tatccgtgct tttgtttttc gaaattactt cggtggcctc cttgatcacc
    45301 gaagtaaaag gacaaacaca ctcttcggag cattcgtcac aatctttcaa acaatcagaa
    45361 caatcaacca ttaaaagcca atcaactgaa acagctaacg tcaaagaagc cattcaagaa
    45421 tcagcggaaa aggtacaaag tcagtcatca caatcaacac aagacagtac aaaaacgagc
    45481 cgagatccgg ctgtcaaaag cgtcgcaatc agctttgatg atggaccagg agcgaccaca
    45541 acaccgcagc ttctgcgaat cttaaaagaa aaaaacgtgc atgccacttt tttcgtctta
    45601 ggagaaaata cggcgcagca tcctgaaatc gtgaagcaga cagctgaagc agggcacgag
    45661 attggcaatc acacatacga tcatcagaat ctggccactc tttctgccca gtcgatgacg
    45721 gaggaagtga cgaaagcaga cactgagatc aaaaaagtca ctggcaaaac ccccactttt
    45781 gttcgtccgc cctatggttc tgtcacgaat gtaggagcaa cgatcatcca gcgaccgatc
    45841 atcgaatggt ctgttgattc agaagattgg aagacaagaa atcctgattt gattttgcag
    45901 aagatccaag caacagtata cgatggggca attattttat tccatgatat ctatcctgaa
    45961 acgattcgtg ccgttcctca agtgatcgat tatctgaaag agcaagggta tcgcatcacg
    46021 acagttgggg atttattagg gcatccaacg gctgtcgaga actattatgg cagaaacgat
    46081 catcggccag ttcagtaagt gagacaagta tctttaataa ataacacatt ttaataagta
    46141 gttgaacaca taactacctt acttgcaaag gcttaacaat atctatacag gtacaacaaa
    46201 aaactgtcca ccaattttct ttggcggaca gttttcactt aaaaataaag aagcaactat
    46261 tcgtaaatta tgctaaaata gcagtagaac gcgtcctgag ggaatcgaac ccccgtctca
    46321 agaaccggaa tcttacgtga tatccactac actaaggacg caagcactgg gataattgta
    46381 actaaacaga taaaaaatta caaggggatt ggacaaaaaa atgaaatttg agcaaaattt
    46441 ttcacaaaaa cagcagcaga cacagaaact agccatgacg caacagttgc aacagtccat
    46501 ccaagtttta caatataaca gtgaggagct gttggcattc gttgagaatc aagcaatgga
    46561 aaatccattg gtggaagttg ttgagccgga atggcagcca gattacataa aagcttcttc
    46621 atcttcttat gaaggagaag agacaaatta cctaaatcag attcctgata caaaagggtc
    46681 tttatttgat tcattgatcg aacaagtcca tttgaattac cgagatactt ttttgaggaa
    46741 aatcgttctt tatcttgtag aatacatcga tttgaacgga tttttgacga ttagtttaga
    46801 agaagccgga aaagagattg gagctacgcc tatccaaatg ctcgatgcgt tgactctgat
    46861 tcagcaatta gaaccagctg gagtaggtgc acgtagtttg caagaatgtc tcatgcttca
    46921 aacagaacga gatgattatg cgccggaatt agcttatatc gtgttggaag aatgttttga
    46981 ggaactggtg gagcgaaaat ggaaagaaat cgcacaacgt ttttctgttg atctacatgc
    47041 tgttcagcag atattcgact atttacaaac gttgagtcca agccctggcc ggattttcga
    47101 ccgtagcagc gaattgtaca ttattcctga tgtccgggta ttagtggacg acgataaaaa
    47161 tgtacaagtt atctcaaacc gaaaaaatca gccaaatata cgctttcaag agagttactt
    47221 caaacaaatg tcacaacaag cagataaaga aactgaaaat tatttaaaag aacggaaaca
    47281 ggaattcgaa tggttgaaga aaacgatcct acaacgtggg gatacaattt tgcgggttgc
    47341 tcaagtcatt gtttcccggc aaaaagcttt ctttatcgac aaggaacgtc caatcaagcc
    47401 tcttacgtta aaggaagttg caactgagat agatgtgcat gaatccacgg tcagtcgtgc
    47461 agtcaacggg aaatatttgg aaacagactt cggtgtattt gaattaaaaa aatttttcac
    47521 tacacgaatt cctacgaata gtacagaaca gacagaagac ctttcagcag atacagcgaa
    47581 gaaaaagctg caggaattag tcgatcaaga agacaaaaac aagccgttgt ctgaccagaa
    47641 attggttgaa ttgctgaaaa aagatgagat agcgatctca agacgaacag tagcaaaata
    47701 tcgtgattta ttaggaatcc cgagttcatc aaaaagaaaa cgttatgata actaatcagt
    47761 caaaagacta gaaaaagtat ttcacttttt ctagtctttt tagttgaaaa acgagagcaa
    47821 aactgttaga cttacagtcg tgaggttgag atttcccttt attgatgtga aattcgaata
    47881 gttaatttct ttttttatcg tatatgggtc gttttaagtc tacattggac gtaaagtgtc
    47941 caactaagga gatcgctatg ctggatgaaa taaaaatgat tgaatctgtt gcaccagata
    48001 ttatcgaagt gttgcaagaa cgctataaaa ttttacgaaa tatctattgg atgcagccga
    48061 ttggacgtcg aagtttatcg gaaagtatgg ggatcacaga acgagtattg cgaacagaaa
    48121 cagatctttt gaaaaatctg aatttgatcg acacctcaaa aagcggtatg acgctgacaa
    48181 ctaagggcga agaagtttat caaagccttg aaaacttcat ggatcagctt ttaggtacgc
    48241 atcaaaccga acaacagttg gcagaatatt ttggtaacca acgctgtatc gttgtttcag
    48301 gaaacagcga agagcagacc aaagtggctg atgcattcgg cgaagcgctg agcgaagccc
    48361 tagaccgact acttccagaa ggcgagaata tcatcgctgt gatgggagga actactatgg
    48421 ctgtggtagc cgaacaattg tctaatctgg aaaataagaa acggcataac ctgtttgtcc
    48481 ctgcaagagg cgggattggt gaagcgataa ctgtacaggc aaattctgtc agtgcaagaa
    48541 tggctgctaa agcaaacggt aaccaccgtg cactttatgt tccggaacaa ttaagtctgg
    48601 caacttacaa ttctttactc aatgagccat ctatccaaga agtcttaaac ttgattagtg
    48661 aagcgaattg tgttattcat agtattgggc gtgcattaca catggcagca cgtcgtaaga
    48721 tgactgaaaa agaattagtc atgctgaaac aagcaaatgc tgttgcggaa tcttttggct
    48781 actttttcaa tgaaaaaggt gaagtcgttt ataaggtccc tagaatcggc atagaattgc
    48841 aagatttgga aaaagtcccg atcatcatgg caatcgcggg cggaaaatca aaagctaaag
    48901 caattcgagc ttatatgaaa aatgcaccaa aacaaacgtg gctcatcact gatgaagctg
    48961 ctgcaaatga gattttaaaa ggggtaaccc tttaaaataa atattttttt gattttcata
    49021 aggaggaaat cttaaatgac agttaaagta ggtattaatg gttttggacg tattggacgt
    49081 ctagcattcc gtcgtatcca agatgtagat ggaatcgaag tagtagcaat caacgacttg
    49141 acagatgcta aaatgttggc acacttgtta aaatacgaca caactcaagg acgtttcaac
    49201 ggaacagttg aagttcatga aggttcattc aacgtaaacg gaaaagaagt taaagtatta
    49261 gctaaccgca acccagaaga attaccatgg ggcgaactag gcgtagatat cgttctagaa
    49321 tgtactggtt tcttcacttc taaatcagca gctgaaaaac atttaacagc tggtgctaaa
    49381 cgcgttgtta tctctgctcc tggcggaaac gatgttccaa caatcgttta taacacaaac
    49441 cacgaaacat taactggtaa agaaacagtt atctcaggtg cttcatgtac tactaactgt
    49501 ttagctccta tggctaaaac attgaacgac aaatttggtg ttgttgaagg attaatgaca
    49561 actatccacg cttacacagg tgaccaaatg actctagacg gacctcatcc taaaggtgac
    49621 ttccgccgtg cacgcgctgc tgctgcaaac atcgttccta actcaacagg tgctgctaaa
    49681 gctatcggtt tagtaattcc tgaattgaac ggtaaattag acggagctgc tcaacgtgtt
    49741 cctgtaccaa caggttcatt aacagaatta gtaacagttc ttgaaaaaga agtaactgtt
    49801 gacgaaatca atgcagcaat gaaagaagct tcaaacgaat cttacggata caacacagac
    49861 gaaatcgttt cttcagatat cgttggtatg acttacggtt cattatttga tgctacacaa
    49921 actaaagtaa tgacagttgg cgacaaacaa ttagttaaaa ctgttgcttg gtacgacaac
    49981 gaaatgtcat acactgcaca attagtacgt actttagaat acttcgctaa cttataagat
    50041 agacaaacgt acaagtgtaa attatagaca tgtacattta aaagcgggga agcaatcgcg
    50101 cttcttccgc tttttttgat aataagttta ttcaggagga aataaaatgg ctaagaaaac
    50161 agtgaaagat atcgatttaa aagacaaaaa agttcttgtc cgtgttgact tcaacgttcc
    50221 tttgaaagac ggcgtgatca ctgacgacac tcgtatcaaa gcagcattgc caacaatcaa
    50281 ctacgttcta gaacaaggcg gaaaagcaat ccttttctct caccttggac gtgtaaaaac
    50341 agaagaagat aaagaaggaa aatctttagc tccagttgca aaacgtctag gcgaattatt
    50401 aggtaaagaa gtaacattcg tacctgaaac tcgcggagaa caattagaag aagcaatccg
    50461 caacatgaat gacggcgacg ttgtcgtatt cgaaaataca cgatttgaag atattgacgg
    50521 taaaaaagaa agcaaaaatg atacagaact aggtaaatac tgggcttcat taggcgatgt
    50581 atttgttaac gatgctttcg gtacagctca ccgtgcacat gcttctaacg taggtatcgc
    50641 ttcaactggt atcccaacag ttgctggatt cttgatggaa aaagaaatca agttcatcgg
    50701 tgaagcagta gaagaaccaa aacgaccaat gattgcaatc cttggtggcg caaaagtttc
    50761 tgataaaatc ggcgtaatcg aaaacttgat tcctaaagca gataaaatct tgatcggtgg
    50821 cggaatgact tacacattct acgaagcaaa aggaatcaag atcggtaact ctctagtaga
    50881 agctgataaa gtggaactag caaaagaatt aatcgaaaaa gcaggcgaca aacttgtctt
    50941 gccaatcgac aatgtctgtg caccagaatt ttcaaatgat gttgaaacac aagtaatcga
    51001 aggagacatt cctgatggtt tgatggcttt agacatcggc ccagcatcag taaaattatt
    51061 tgctgataca ttacaaggtg caaaaacagt tgtttggaac ggacctatgg gtgtatttga
    51121 aatgagtaac tttgctaaag gtacaatcgg tgtttgtgaa gcaatcgcta acttagaagg
    51181 cgcaacaaca atcatcggtg gcggagactc agctgcagca gcagaacaat taggatttgc
    51241 tgacaaattc acacacatct caacaggtgg tggcgcaagc ttggaattgc ttgaaggtaa
    51301 agaattacca ggactagcag caatcaacga taaataaacg accaagtttg ctcaattctg
    51361 acgagtaatc gatcaaaagg tgaagggagt tttcatgact ccctagccat ttttcaataa
    51421 attaaggagt gtgttcctca atgcgtaaac ctattatcgc aggtaactgg aaaatgaaca
    51481 aaactgcatc agaagcaaaa gaatttgctg aagcagtaaa aaacaaaatc ccttcaaatg
    51541 acaaagttga ttcagtcatc ggatctcctg cattattctt acaagaatta atgacatcag
    51601 ctgaaggtac agaactaaaa atctcagcac aaaactgcta ctgggaaaac tcaggtgcgt
    51661 tcactggtga aacttcacca gcagctcttg ctgatctagg tgttcattat gtgatcatcg
    51721 gacattcaga acgtcgtgaa tatttccatg aaacagacga agacatcaat aaaaaagcaa
    51781 aagctatctt tgcaaatggt atgacaccaa tcctatgctg cggcgaatct ttagaaacct
    51841 atgaagcagg caaaactgct gaatggatcg aaggacaaat tacagctggt ttagctgatc
    51901 tttcagctga acaagtgtca aacatggtta ttgcttatga accaatctgg gcaatcggta
    51961 ctggtaaatc agctgacgca caaatcgctg acgaaatttg tggagttgta cgtcaaacag
    52021 ttgaaaaact ttatggaaaa gaagtatcag aagcagttcg tatccaatac ggcggttctg
    52081 taaaaccaga aaatattgct gaatacatgg caaaagaaaa tgttgacggt gctttagtcg
    52141 gtggcgcaag cttgcaagca gattcatttt tgtcattgtt agacgctgta aaataattgt
    52201 tgaaaatttg cgaaaaatgc aagaaatgtt tgcactaatg agcaaaatta actaaaatcg
    52261 tatatgaggg aaatccctta ggaaaaaaca aactcaaagg agagacaaaa catgtcaatt
    52321 attactgatg tttacgctcg cgagatctta gactcacgtg gtaacccaac aatcgaagta
    52381 gaagtataca cagaaagcgg agcttttggc cgcggaatgg ttccttcagg tgcttcaact
    52441 ggtgaatacg aagcagttga attacgtgac ggagacaaag ctcgttatgg cggtaaaggt
    52501 gtaactaaag ctgtcgacaa cgtaaacaac atcattgctg aagcaatcat tggctacgat
    52561 gttcgtgacc aaatggctat cgacaaagct atgatcgctt tagacggaac tcctaacaaa
    52621 ggtaaattag gtgcgaacgc tattttaggt gtttctatcg ctgttgcacg tgcagctgct
    52681 gactacctag aagtaccttt ataccactac ctaggcggat tcaacacaaa agtattgcca
    52741 acaccaatga tgaacatcat caacggcgga tcacatgctg ataactcaat cgacttccaa
    52801 gaattcatga tcatgcctgt tggcgctcca acattcaaag aagctctacg tatgggtgct
    52861 gaagtattcc acgcattagc ttcaatcttg aaagctcgcg gattagcaac ttctgttggt
    52921 gacgaaggtg gatttgctcc aaaccttggt tcaaacgaag aaggttttga agtaatcatc
    52981 gaagcaatcg aaaaagctgg ctatgtacct ggtaaagacg ttgttcttgc tatggatgct
    53041 gcttcttcag aattctacga caaagaaaaa ggtgtttacg tactagctga ctcaggcgaa
    53101 ggcgaaaaaa caactgacga aatgatcaaa ttctacgaag aattagtttc taaatatcca
    53161 atcatctcaa tcgaagatgg attagacgaa aacgactggg acggattcaa gaaattaact
    53221 gacgtattag gcgacaaagt tcaattagtt ggtgacgact tgttcgtaac aaacactcaa
    53281 aaattatctg aaggtatcga aaaaggaatt gctaactcaa tccttatcaa agtgaaccaa
    53341 atcggtacat taacagaaac tttcgaagct atcgaaatgg ctaaagaagc tggctacaca
    53401 gcagttgtat ctcaccgttc tggtgaaaca gaagattcaa caatctctga tatcgctgtt
    53461 gcaacaaatg ctggccaaat caaaactggt tctctatcac gtactgaccg tattgctaaa
    53521 tacaaccaat tactacgtat cgaagaccaa cttggtgaag ttgcagaata caaaggtttg
    53581 aaatctttct acaacttaaa aaacaaataa ttcttttcta atgaagatac atgatcgact
    53641 attgaaagat agtcgagtat gatcacttag ttaagtaatc gaactctcta cttgctgaaa
    53701 tatcagcagg tagagagttt
//
LOCUS       DAIGSZ010000013        53261 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.013, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000013 DAIGSZ010000000
VERSION     DAIGSZ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53261
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.013"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            555..3194
                     /locus_tag="NOB31_000787"
     CDS             555..3194
                     /locus_tag="NOB31_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI0973021.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3362..4060)
                     /locus_tag="NOB31_000788"
     CDS             complement(3362..4060)
                     /locus_tag="NOB31_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCI0973022.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            4278..5423
                     /gene="tgt"
                     /locus_tag="NOB31_000789"
     CDS             4278..5423
                     /gene="tgt"
                     /locus_tag="NOB31_000789"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HCI0973023.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            5520..5900
                     /gene="yajC"
                     /locus_tag="NOB31_000790"
     CDS             5520..5900
                     /gene="yajC"
                     /locus_tag="NOB31_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HCI0973024.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            6205..8802
                     /gene="adhE"
                     /locus_tag="NOB31_000791"
                     /gene_synonym="adhC"
     CDS             6205..8802
                     /gene="adhE"
                     /locus_tag="NOB31_000791"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HCI0973025.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            9031..10137
                     /locus_tag="NOB31_000792"
     CDS             9031..10137
                     /locus_tag="NOB31_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCI0973026.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            10154..11182
                     /locus_tag="NOB31_000793"
     CDS             10154..11182
                     /locus_tag="NOB31_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HCI0973027.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            11188..11667
                     /locus_tag="NOB31_000794"
     CDS             11188..11667
                     /locus_tag="NOB31_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HCI0973028.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            11683..12978
                     /locus_tag="NOB31_000795"
     CDS             11683..12978
                     /locus_tag="NOB31_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HCI0973029.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            12989..13813
                     /locus_tag="NOB31_000796"
     CDS             12989..13813
                     /locus_tag="NOB31_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCI0973030.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            13978..14877
                     /locus_tag="NOB31_000797"
     CDS             13978..14877
                     /locus_tag="NOB31_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973031.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(15003..15872)
                     /locus_tag="NOB31_000798"
     CDS             complement(15003..15872)
                     /locus_tag="NOB31_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HCI0973032.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            16025..17485
                     /gene="rhaB"
                     /locus_tag="NOB31_000799"
     CDS             16025..17485
                     /gene="rhaB"
                     /locus_tag="NOB31_000799"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HCI0973033.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            17482..18738
                     /gene="rhaA"
                     /locus_tag="NOB31_000800"
     CDS             17482..18738
                     /gene="rhaA"
                     /locus_tag="NOB31_000800"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HCI0973034.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            18752..19597
                     /gene="rhaD"
                     /locus_tag="NOB31_000801"
     CDS             18752..19597
                     /gene="rhaD"
                     /locus_tag="NOB31_000801"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HCI0973035.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            19599..19910
                     /gene="rhaM"
                     /locus_tag="NOB31_000802"
     CDS             19599..19910
                     /gene="rhaM"
                     /locus_tag="NOB31_000802"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HCI0973036.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            19992..21143
                     /gene="fucO"
                     /locus_tag="NOB31_000803"
     CDS             19992..21143
                     /gene="fucO"
                     /locus_tag="NOB31_000803"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HCI0973037.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            21270..22028
                     /locus_tag="NOB31_000804"
     CDS             21270..22028
                     /locus_tag="NOB31_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HCI0973038.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            22128..22772
                     /locus_tag="NOB31_000805"
     CDS             22128..22772
                     /locus_tag="NOB31_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HCI0973039.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            22779..23786
                     /locus_tag="NOB31_000806"
     CDS             22779..23786
                     /locus_tag="NOB31_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HCI0973040.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            23802..24644
                     /gene="kduI"
                     /locus_tag="NOB31_000807"
     CDS             23802..24644
                     /gene="kduI"
                     /locus_tag="NOB31_000807"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HCI0973041.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            24664..25467
                     /locus_tag="NOB31_000808"
     CDS             24664..25467
                     /locus_tag="NOB31_000808"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HCI0973042.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25716..26780)
                     /locus_tag="NOB31_000809"
     CDS             complement(25716..26780)
                     /locus_tag="NOB31_000809"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HCI0973043.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26777..27862)
                     /locus_tag="NOB31_000810"
     CDS             complement(26777..27862)
                     /locus_tag="NOB31_000810"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HCI0973044.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(27875..28852)
                     /gene="mvaD"
                     /locus_tag="NOB31_000811"
     CDS             complement(27875..28852)
                     /gene="mvaD"
                     /locus_tag="NOB31_000811"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HCI0973045.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(28845..29789)
                     /gene="mvk"
                     /locus_tag="NOB31_000812"
     CDS             complement(28845..29789)
                     /gene="mvk"
                     /locus_tag="NOB31_000812"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HCI0973046.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            30105..30764
                     /locus_tag="NOB31_000813"
     CDS             30105..30764
                     /locus_tag="NOB31_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI0973047.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            30849..31754
                     /locus_tag="NOB31_000814"
     CDS             30849..31754
                     /locus_tag="NOB31_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI0973048.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(31756..32388)
                     /locus_tag="NOB31_000815"
     CDS             complement(31756..32388)
                     /locus_tag="NOB31_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCI0973049.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    32539..32664
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            32708..33232
                     /gene="infC"
                     /locus_tag="NOB31_000816"
     CDS             32708..33232
                     /gene="infC"
                     /locus_tag="NOB31_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HCI0973050.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            33304..33504
                     /gene="rpmI"
                     /locus_tag="NOB31_000817"
     CDS             33304..33504
                     /gene="rpmI"
                     /locus_tag="NOB31_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HCI0973051.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            33557..33916
                     /gene="rplT"
                     /locus_tag="NOB31_000818"
     CDS             33557..33916
                     /gene="rplT"
                     /locus_tag="NOB31_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HCI0973052.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            34168..35505
                     /locus_tag="NOB31_000819"
     CDS             34168..35505
                     /locus_tag="NOB31_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HCI0973053.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            35553..37682
                     /locus_tag="NOB31_000820"
     CDS             35553..37682
                     /locus_tag="NOB31_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HCI0973054.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            37657..38346
                     /locus_tag="NOB31_000821"
     CDS             37657..38346
                     /locus_tag="NOB31_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973055.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(38754..39367)
                     /locus_tag="NOB31_000822"
                     /pseudo
     CDS             complement(38754..39367)
                     /locus_tag="NOB31_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(39503..39697)
                     /locus_tag="NOB31_000823"
     CDS             complement(39503..39697)
                     /locus_tag="NOB31_000823"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973056.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(39747..40187)
                     /locus_tag="NOB31_000824"
     CDS             complement(39747..40187)
                     /locus_tag="NOB31_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HCI0973057.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(40191..41036)
                     /locus_tag="NOB31_000825"
     CDS             complement(40191..41036)
                     /locus_tag="NOB31_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HCI0973058.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            41185..42603
                     /gene="pepV"
                     /locus_tag="NOB31_000826"
     CDS             41185..42603
                     /gene="pepV"
                     /locus_tag="NOB31_000826"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HCI0973059.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(42660..43607)
                     /locus_tag="NOB31_000827"
     CDS             complement(42660..43607)
                     /locus_tag="NOB31_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0973060.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(43830..44180)
                     /locus_tag="NOB31_000828"
     CDS             complement(43830..44180)
                     /locus_tag="NOB31_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCI0973061.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            44380..45459
                     /gene="pepA"
                     /locus_tag="NOB31_000829"
     CDS             44380..45459
                     /gene="pepA"
                     /locus_tag="NOB31_000829"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HCI0973062.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            45603..45923
                     /locus_tag="NOB31_000830"
     CDS             45603..45923
                     /locus_tag="NOB31_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCI0973063.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            45945..46409
                     /locus_tag="NOB31_000831"
     CDS             45945..46409
                     /locus_tag="NOB31_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI0973064.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            46614..47219
                     /locus_tag="NOB31_000832"
     CDS             46614..47219
                     /locus_tag="NOB31_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HCI0973065.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(47258..48547)
                     /locus_tag="NOB31_000833"
     CDS             complement(47258..48547)
                     /locus_tag="NOB31_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HCI0973066.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            48975..49454
                     /gene="rlmH"
                     /locus_tag="NOB31_000834"
     CDS             48975..49454
                     /gene="rlmH"
                     /locus_tag="NOB31_000834"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HCI0973067.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            49539..50048
                     /locus_tag="NOB31_000835"
     CDS             49539..50048
                     /locus_tag="NOB31_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HCI0973068.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            50148..50798
                     /locus_tag="NOB31_000836"
     CDS             50148..50798
                     /locus_tag="NOB31_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973069.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            51249..52187
                     /locus_tag="NOB31_000837"
     CDS             51249..52187
                     /locus_tag="NOB31_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCI0973070.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            52200..53252
                     /locus_tag="NOB31_000838"
     CDS             52200..53252
                     /locus_tag="NOB31_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0973071.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
BASE COUNT        16909 a         9576 c        11435 g        15341 t
ORIGIN      
        1 aagccgagct ctcgataagc tcggctttct tgtacctcgg aaggattcaa ataaacagaa
       61 atgattgtaa ctttccatca tacatgcaaa gcacggtgtt gaatttcttc atgttaaaca
      121 aaaattttgt tttcgttaca tcttcaacat ttgaaacatc tcttgttcct attcaatttt
      181 cagacgttta cgttattcaa ttgttacgta tcgcattact tcttgtttcg gatacttcgt
      241 gatccaaaca tccatacgca ttcactattt ataggtttgt actctacacg catgtctggg
      301 tgaaacctgt acttctaaca actttgtttg cttacactgt tctatcgaga aattcttctg
      361 tctatttgat ggtatcctcc ttccttacat ctatataata gcatcctttg gtagcgtttg
      421 caaatataag cactttaaat tttacgcttt cttaacaaat aatcgataag ccctttattt
      481 gaagtaaata aaaaaaggat gttatagtaa aataagtacc tttttttgta cgaagatttt
      541 aaaggaggaa taggatggaa gaatacaagc agacaataga agaagtaaag aaggtaacag
      601 aagcagatcc agatactggg ttgtcttcac aagaagtgga tgaacggcga aaaaagcagg
      661 gattgaataa attcgatgag gcgccgaaag aatcgatgat caaaaaattc tttcgaagct
      721 tgtccgattt tacaacgatc atccttcttg tagcagcggt gatttccttt tataccgcat
      781 ttgctacaga acatggggat ttatttgaag gactgctgat catcgctatc gttgtgatca
      841 actcggtatt ggcgattgtc caagaaggaa acgcagaaaa agcactggaa tccttgcaag
      901 atatgaataa acaaacggca actgtcatac gagacggcaa agtgaccact gttgagtcag
      961 agcaactggt agtgggtgat attcttgttt tagagtccgg tgatgctatt tctgccgatg
     1021 cccgtttgat cgaagcatca caattacgtg tagaagaatc ggcgttgact ggagaaagtg
     1081 aagcagttga aaaagatgca gcatttattg ctgaagaaga tgagtcatta ggtgaccaac
     1141 ttaatatggt atttaaagga tgtacggttg ctgcaggtcg tgggaaagcg atcgtcactg
     1201 ccattggcat ggctacagaa atgggtaaga tcgcggatct tttgaacgaa aatactatgc
     1261 aaaaaacacc tttacaggtc cgattgaatc agctaggcaa acgaatcagt atgatcgctt
     1321 tagcggctgc ggctttagta tttgtgattg gtgaactgca aggagaacca ctccttgaga
     1381 tgttcatgac ttcgatttcc ttggctgttg cagctgtacc ggaaaccttg actgttattg
     1441 ttacgttgac acttgcatac ggtgtgcaga agatggcgag gaaacatgcg atcatccgac
     1501 agttgccagc agttgaaacg ctaggaaccg ctaatgttat ctgctcagac aaaacaggaa
     1561 cgctgacaca aaatgaaatg cgcgtccgcc gggtatggag caaagaagat gaagtaacga
     1621 atatcgaaga ttcaatgacg aacagcgcga tggaaatatt gaaaatggct gcactatgta
     1681 cagatgtgac ggtcgagcaa gaagatgacg accttgttat caaaggtaat ccaacagaag
     1741 tagccatcgt aagggctgtt gaagagaatt atcatacaaa ggcagaatta gaagaaaaat
     1801 atccacgagt aaacgagctt ccttttgatt ctgaacgaaa aatgatgaca acagttcacc
     1861 aaatgggcga aaaatacatc tcaatcacca aaggagcatt cgatgttctt gctccgcgct
     1921 ttagttcagg cgatgtagaa caagcggcga tcgttaatga tcgctttggt aaacgggcac
     1981 tgagagtgat tgctgttggt tatgctactt atgacgaaga accgcaagat atttcttctg
     2041 aagcactgga aaaagactta cgtttgattg gtctgatcgg aatgatcgat ccaccacgtc
     2101 cagaaagtaa aggagcaatc aagcgagcga aaaaggctgg catcaaaaca gtcatgatca
     2161 ctggagatca tgtggtgact gccagtgcca tagcgaaaga attaggtatc ttgaatgatc
     2221 cgtcagaagc actttcagga tcagaactgc atcaattatc agacgaagaa ttagatgcgc
     2281 gtgtcaaagc tctctctgtc tatgctcggg taacgccaga agacaagatc cggatcgtca
     2341 aatcttggca acgtacgggt gcagtcgtag cgatgactgg ggatggtgtg aatgatgcac
     2401 cagcgttgaa agcaagtaac gttgggtgtg ccatggggat cacaggaaca gatgtggcgc
     2461 aaagtgccgc agatatgatt ttgacggatg acaactttgc gacgatcgta gacgctgtca
     2521 gtcaaggacg ttcggtttat cagaatattc gtaaagctat caactttttg ctaagctgta
     2581 atatttcgga gatctttatt gttttgattg cgatgctgtt aggatgggga gcaccattta
     2641 cagctgtgca actactgttt gtcaatgtag ttgctgatgg acttccagga tttgctttag
     2701 gaagagagcc agcggaacac ggcatcatgg atcagccacc cattccgaaa aatgaaggga
     2761 tctttgctcg aggtttattg caaaaaattg ccataaatgc aggggtcttc accatcgtaa
     2821 ccttgtttgg ttattattta ggtagttatg tcgatactat cagcccatgg gtagacgcaa
     2881 gtcagcatgt cggtcaaact gttgcattct tgatcttagc ttattcatcg attctgcatg
     2941 tgttcaatgt acgcagcagc caatcgatct tcaaagtcaa tttagcgacc aataaagctt
     3001 tggtagaaat ggcgttactg gcattagcta ttacaacggc tgttgctttg ctgccattta
     3061 cgcaagaact attcggccta gtacacatca gtttgaatca ctggttcttg gtagggattt
     3121 tatctatcgt accaatcgcg gtgaatgaac tgatcaagtt ccatcgatta ccggaagcag
     3181 aagaagagga atgattaact gtttctaagt tgattttctt tttactggaa ctatacaaaa
     3241 aggaggtgtg acatgaatgt tgtcacacct cctttttgct aatgggctga atgtttcttt
     3301 tactgcctct cgataaacgg tgttctcctg ccaccccctc ggtcacaagt cacactctct
     3361 tttaaatatc ttttggcaat tgttcataaa atgctgcttt tgttgcagaa atgtatgggc
     3421 tgagccatag ataaccaata ccagcagttg ctaatgctaa gatatgccag ccgataaatg
     3481 aaagatctaa ccagaaaagt tgtcctttat aaccatccat caattttcga cttgcagtga
     3541 tcgtatccag tactttaggt gtttgtcctg tttcttggac gatatcgtag taaataaaat
     3601 agctttgaga ataagaatag cttttaatga ttccaggaat aactaatagc aaaccccata
     3661 atgttgtaaa gatcgagatc agcacagcta agctgatcac tccgccgata aacaaacctt
     3721 tgaatccacg aaatgcatct ttgaatggtt cgatctgatc tttttgtcca cgtaaaatat
     3781 caagataagt ccaagaaata ccgctcatga acaaagcgct aatgatgctg gaaataattc
     3841 cgccaccgcc tcctgaacta ccgcctcctg aagttgtcgc ttctgagacg ctcgctgatc
     3901 catcatatat ggtggtggca aacaagataa taggaatcat aataagaaga atagtagcaa
     3961 taccaatcaa tgtagggatt agatttagta aaacagcttg tccccaacgt ccttttagac
     4021 tctcttttgc ttggcgtttt aattctgcag aagattgcat gatttttccc tccttttctt
     4081 taataacacc aatataccat gtatcaaaaa atatttctgt cataatgttt ttcttttttt
     4141 tgttattcat aaaaaaagga taaaaaaaag aatattaaat aaagtagaag gaagccgagg
     4201 gaacttgcaa aaagcacttg aaacgattat gatggtggga gttgtcaaga tattttatat
     4261 agaaagtagg gaaatgaatg acgcaacctg ccattcgcta tcgtttaatc aagaaagaaa
     4321 aacatactgg cgcgcgttta ggggaattga tcacgccaca cggaactttc cccacaccaa
     4381 tgttcatgcc agtaggaaca ttagctacag taaaaacaat gtccccagaa gagttgaaag
     4441 aaatgggtgc tggcgttatt ttaagtaata catatcattt atggctacgc cctggtgaag
     4501 acttagtaga agaagctggc ggactgcata aatttatgaa ctgggatcaa ccgattttaa
     4561 cagattcagg cggctttcaa gttttttcat taagtgatat gcggaatatc gaagaagaag
     4621 gcgtgcattt caaaaatcac ttgaacggtt cgcgtatgtt tttatcacca gaaaaagcaa
     4681 tcaacatcca aaataaattg ggctctgata tcatgatgag ttttgacgaa tgtccaccat
     4741 tcgatgaaag ttacgactac gtgaaaaaat cagtagaacg tacgtctcga tgggcagaac
     4801 gaggattgaa agctcatgct aatccagacc gtcaaggatt atttggaatc atccaaggag
     4861 cagggtttga agatcttcgt cgtcaaagcg cgaaagatct agtcgggatg gatttccctg
     4921 gttactcaat cggcgggtta tctgtcgggg aacctaaatc agaaatgaat cgtgtattag
     4981 aattcactac accgttgatc cccgaaaaca aaccacgtta cttgatgggt gtcggtgctg
     5041 ctgattcatt gatcgatggt gttatccgtg gagtagacat gtttgactgt gtcttgccta
     5101 ctcgaatcgc tcgaaatggc acatgtatga cttctcaagg ccgtctagta gtgaaaaatg
     5161 cgaaatatgc ccatgatttc cgtccaattg atgagaaatg tgattgttat acatgtaaaa
     5221 actatacacg tgcctatatc cgccatttga tcaaatgtga tgaaacattt gggattcgtt
     5281 tgacttctta ccacaattta tacttcttgt tgaatctaat gaaacaagta cgtcaagcaa
     5341 tcatggatga taatttgctt gaatttagag aagccttttt tgaagaatac gggttcaata
     5401 aagaaaacgc aaaaagcttc taaaggaaaa tcttttaaaa attaagtaaa aaactagtgt
     5461 tatcagcatt tttctgctaa agtgtttttt gtagatacag aattagtgag gtgaaaaaaa
     5521 tgggaacatt accaatgctt gtgatgttta tcgcgctatt agcaatgtgg ttttttatgt
     5581 cacgttcgca aaagaaacaa cagcaagaac gtcaaaactt gttagatagc atgaaaccag
     5641 gtgattcagt cgtaacgatc ggcggattac atggagttgt ttcagaaatc gacaatgaca
     5701 aacggacagt tgttttagac tgcgaaggga tcttccttga gtacgatcgt gcagcaatca
     5761 aaacggtcaa accagggact gtcgtaacaa atgatgcaac gactactgtt gaaacaacag
     5821 aagaaccagc tgagacagtt gaagtaaaaa ctgaaacaac agaaacgctg gaagagacag
     5881 aagagaagga agaaaaataa gtatcaaagc ttatttaaag acgaggtagg gcagaaagat
     5941 gtcctacctc attttttatt caaaaaagaa agagataaga gcatgggata tattgctcaa
     6001 tattgaataa tcgggtgtgt catataaata ataataaata actttatata tttttctata
     6061 caaacacctg taaataaagc aattttatat ttaaaaataa ctgtgaaaaa aatcacaaaa
     6121 aagtgtttac atagaaaaat aaatattgta tgatatacat gtgaattatt taacaaataa
     6181 ccatgaccca ttaggaggat aatgatggct aaagtaatag aaaaagaaaa aacgaagaca
     6241 attgacgtac aagcaatgat tgatgatttg gcagaaaaag caaatgcagc attgaaagaa
     6301 atggaaagct ttgatcaaga aaaagtagac catatcgtgc atgaaatggc aatggcagct
     6361 ttggatcaac atatgccatt agcgaagatg gctgtagagg aaacaggccg cggtgtttac
     6421 gaagataaag caatcaaaaa tatgtatgcg tccgaatata tttggcataa tatcaaacat
     6481 gataaaacag ttggtgtgat caatgaagat gtccaaaaag ggttgattga aattgctgaa
     6541 ccagtcggtg tggtttgcgg agtaactcca acaacgaatc cgacttccac aacgattttc
     6601 aaatcaatga tcgcgttgaa aacaagaaat ccaatcgttt ttgctttcca tccaagtgcc
     6661 caaaaatctt ctgcagaagc agcacgagtg gtacgtgatg ctgctatcgc tgccggagct
     6721 cctgaaaatt gtatccaatg gatcgaacat ccttcgatcg aagcgacttc tatgctaatg
     6781 aaccatccag gtatcgcgat cgtcttagcg acaggtggag ctggaatggt caagtctgct
     6841 tactctacag gaaaaccagc tttaggtgta ggtccaggta acgtaccagc ttatattgaa
     6901 aaaacagcaa aaattaaacg tgcagtgaac gatttgatcg tttcgaaaac atttgataat
     6961 ggaatgattt gtgcttctga acaagctgtg atcgtggata aagaaatcta tgcagcagta
     7021 aaagcagaat tccaagcaca ccaagtttat atcgtaaaac cagatgaatt gcaaaaatta
     7081 gaagatgcag tgatgaacga aggaaaatat gcggtcaatc catcaatcgt tggacattct
     7141 gcgatggaaa tcgcaaaatt ggcaggaatc agtgtaccaa aaggaacgaa aatgctgatt
     7201 gctgaattgg aaggcgtagg cccagattat ccgctatcaa gagaaaaact ttctccagtt
     7261 cttgccatga tcaaagctaa caacacggac catgcgtttg atttgtgtga aggtatgttg
     7321 aatcttggag gattaggaca tacagcagtt atccattcag aaaacgaaga gttgcatgtc
     7381 aaattcggtc ttcgaatgaa agcttgtcgt attttagtga atacaccatc tgcagaaggc
     7441 ggcatcggtg atatctataa cgaaatgatt ccgtcattga ctttgggatg cggttcttat
     7501 ggtaagaact ctgtttctcg taacgtctct gctgtaaact taatcaatgt caaaactgta
     7561 gcgaaacgga gaaataacat gcaatggttc aaattaccgc caaaaatctt ctttgaaaag
     7621 aactctctat tgtacttaga gaaaatggaa aacgttgaac gtgtcatgat cgtttgtgac
     7681 cctggtatgg tccaattcgg ttactgcgat acagttcgtg aagtattggc acgacgtaaa
     7741 aatgatgtga agatcgaagt cttctcagat gttgaaccga acccatcgac aaataccgta
     7801 tacgcaggaa cgaaactgat ggcagacttc aagccagata cagtaatcgc tcttggaggc
     7861 ggttctgcaa tggacgcagc taagggaatg tggatgttct atgaacaccc agacacatct
     7921 ttctttggtg caaaacaaaa attcttggat atccgtaaac ggacatataa gatcgacaaa
     7981 ccagaaaaaa cacaattcgt atgtatcccg acaacatcag ggactggttc tgaagtaacg
     8041 ccatttgcgg tcatcactga cagtgaaaca catgtgaaat atccgttagc agattatgca
     8101 ttgacgccag atgtcgcaat cgtcgatcct caattcgtca tgtcagttcc agcatctgtc
     8161 acagcagata ccgggatgga tgtgttaaca catgcaatcg aatcctatgt ttcagtcatg
     8221 gcttcagatt atacacgtgg attgagccta caagcaatca agttagtctt tgactattta
     8281 gaaaaatcag taaaaacacc tgatatggaa tcacgtgaaa aaatgcacaa cgcttctaca
     8341 atggctggta tggcgtttgc taacgcattc ctaggtattt gtcactcagt cgcacataaa
     8401 atcggcgggg aatacgggat ccctcatgga cggacaaatg cgattctttt accgcatatt
     8461 atccgctata atgcaaaaga tccacaaaaa catgcgatgt tccctaaata tgactatttc
     8521 cgtgcagata cagattacgc agatatcgca aaattcttag gtctgaaagg cgaaacaaca
     8581 gaggaattag tcgaagcttt agcaacggct gtttatgaat taggaaaatc tgtcggcatc
     8641 aacatgagtc taaaagctca aggagtcaca caagaaacac tagatacaac cgtagaccgt
     8701 atggctgaat tagcttacga agaccaatgt acgacagcta atccgaaaga accattgatc
     8761 tctgaattga aacagatcat cattgatgct tacaacggat aagcaaaaga aagcgtagaa
     8821 aaaagataag aaaatagatg aaaaagaact tggaaaacgt tgtttctcca agttcttttt
     8881 ttaatttcca agtaactgaa agttactttt gttatttaac atttaggtca attttagaca
     8941 gtttttgttc aaaaagcgat atttatagtg gacggtatta ctgctatatt aaggatataa
     9001 aatgaaagcg tttaaaaagg tggcgtaaag atgattatta aagaagagat ttttgtacct
     9061 aaagaattag tgaaagaaaa aattgacctg ctcgttgaaa acctgacaac gatcaaagac
     9121 gataatggtg aatttttgtt ggactttgat ggactgaaag tagatgacaa aagctggaca
     9181 gtgtggaatt ggccacaagg tgtcggtcta tatggtattt ataaaaatta ccagatgaca
     9241 aaaaatcctc gcgcttatca agtggtcaat gaatggtttg aggatcgtat ggaagaaggc
     9301 gctccgccca aaaacgtcaa tacaatggca ccgctattga ctatggctta cttgtatgaa
     9361 gacacgaaag attcacgcta tttgccttat ttagaacaat gggcagaatg ggtcatgaat
     9421 gacatgcctc ggacaaatga agacgggtta cagcatgcca catatggacc ggaaaataag
     9481 aatcagttgt gggacgatac attgatgatg acagtgcttc ctttggcaaa aatcgggaaa
     9541 ctgttgaatc gcccagaata tttagaagaa gctcgttacc agtttatgat ccatatcaaa
     9601 tacttgatgg ataaacgaac aggattgtgg tatcacggct ggacgtttga aggaaatcat
     9661 aactatgccg aagcattttg ggctcgtgga aactgctggt tgacgattgc tattccagag
     9721 atcattgaaa tcttagaatt atcgaaagaa gatgcattgc gcaaattatt gatcgaaaca
     9781 cttgaagcac aagtgcgtgc attaaaaact tatcagtctg aaagcggttt atggcatacg
     9841 ttgttggatg atccttcttc ttacgtagaa tcttctgcaa ctgcaggatt tgcttacggt
     9901 attttgaaag cggtccataa acgttattta ccacaagaat ataaagaagt cgcttatcgt
     9961 gctatccaag gattgcttga acaaatcgat gaaaaaggag aagttcaaaa cgtttcaatc
    10021 gggacaggaa tgggggacag tttagatttt tatcggaata tcggaatcac agcaatgcct
    10081 tatggacagt cgttaacggt gctttgtttg acagaattgc tcgtctctta ttgttaaaag
    10141 aaaggaaacc catatgaaaa aaacatcact gctgtttgca gcaagttcgc ttagcctagg
    10201 tctgctaggt ctaagcggct gcggaaataa ttctagtgtg gcaactgtcg cagatgcaga
    10261 tgtaaatgag atagttacct tgcgctttgc ttatgcaagc aacagccagc cagtaattga
    10321 tgcaatgaat gaatttgggc gtttagtaaa agaaaaaaca gatggttccg tacagatcca
    10381 gtatttccca gatggacaac tgggtggaga acgtgaactg atcgaattga cacagtcagg
    10441 agcagtagat ttcacaaaag taagtgcctc agcgttggaa agtttctcta aagattattc
    10501 gattttttca gttccttatc tattcaatga tgaagaacat ttctttaagg tgatggataa
    10561 tgaagaaata atggagccaa tctaccaatc gaccaaaaat ttaggattta ccggattgac
    10621 ctattatgat tctggtcagc gcagctttta tatggtagac ggtccgatcc atacgccgga
    10681 agatttggag ggaaagaaga tccgtgtgat gcaaagcgaa accgctatca aaatggtaga
    10741 gcttttaggc ggttcgcccg tacctatggg aagtgatgaa gtgtacacgt ctcttcaatc
    10801 caatttgatc aacggatcag aaaacaatga atttgtcttg tatacagctg gacatggtgg
    10861 tgtggctaaa tactattcct atgatgagca tacacgtgtg ccagatatca tcatcatgaa
    10921 tgatgccatc aaagaacagc taactgatga gcaggaaaaa gccattgaag aagcagcgaa
    10981 agaatcaacg gtttttgaaa ttgaagcttt tgcaaaagca attgaagaag aaaaagcttt
    11041 agcacaagaa gaacatggag tccaattcaa tgatgtagat aatacaccgt ttcgagaggc
    11101 agttgcccca cttcatgata tattcaaaaa cgatcctacc tacaaagacc tttatcaaaa
    11161 gatccaagag caaggagcgt agctgtgatg aaaatgattt taaacaaggt attagagatc
    11221 ctgggagctg ttttgcttgt tgggatggtc gctgttgttt tatggcaagt attttccaga
    11281 acggttttag gaaatccaaa tacggtcacg gaagagcttg ttcgattcgg tcttgtctgg
    11341 tttgccatgt tgtcttccgc gtatgttgtg ggacaaaaag cacatttagc cgtaacggtt
    11401 ttaagtgaaa aattaactgg caaaaaaagt aaaattttag aagttgttgt tcaaagttta
    11461 tttctggtat ttgctgcgat gatcatggtg tatggcggat ggaatgctgt cacattgaca
    11521 atggggcaga tctcgccttc tttaagtatt cctatgggat atgtttatct gtcagtacct
    11581 gtatcggggg tactcatcat tatctatagc ctgatcaatc taatcgatac attaagcaac
    11641 aagccagcaa ttcaagaaaa aatataaaaa tggaggaata aaatggcaat agaagccgga
    11701 ttagtgttat tttttgtatt tgttgtgttg cttgtattag ggatgccgat tgctataagt
    11761 attgcattct catcgatgat gactttattg ttagttatac cgtttgatgt ttctgctttt
    11821 agttcagctc aaaaaatggt gggaagtatc aatagttttt cgctgatcgc tattccgttt
    11881 ttcgttctct cgggcattat catgaataat ggagggatag ctaagaaact agtggatttt
    11941 gcgatgttgt tcgtcgggcg cgtgccgggg gctttggctc atacgaatgt gttagggaat
    12001 gctttatttg gttccatctc tagctcggcc attgccgctt ctaccgcgat tggcggagtg
    12061 ttgatccctc agcaagtgga agaaggatat gaccggaagt ttgcgacagc ggtcaatatc
    12121 gcgtcagctc cgacaggtat ggtcattcct ccaagtactg cttttatcat gtattcactt
    12181 gttgctggtg gtgcttcgat ctctgctttg tttatgggag gttatctcgt aggcgctttg
    12241 tgggcgctag gaatcatgct agtagcattc atcgttgcta aaaagaataa ataccctgtt
    12301 gtcgaaaaag gacagatggc tcatgctgga aaaataataa aagaggcgat tcctagcctt
    12361 ctattgattg tcatcattat cggtggtatc ttgacgggga tatttacagc agtagaagct
    12421 tcagcgatag ctgtcattta ctccctgttg attgctatgt tttactataa aacggtaaaa
    12481 ctaaaagata tacctaatat gttgtttcaa tcagtagcaa tgtcagggac gatcatgttc
    12541 ttattggcta cttcttccat gatgtctttc gccatggcgt ttaccggtat tcctcaggca
    12601 attagttcgt tgattatggg cgtaacggat aataaattta ttattctgtt attagtcaat
    12661 cttgtgttat tactggtggg tatgtttatg gatgtggcgc ctgctatctt gatttttaca
    12721 ccaatatttt taccaatcgt cacaagtgta ggggttgatc ctgtacatta cgggttgttt
    12781 tcaatcatga atctgtgtgt aggctccatc acgccgccag taggtacagg actatatgtc
    12841 ggtgcaagtg taggaggcgt aaaagcagag gcaatgctga aaccgcttct tcctttttat
    12901 ggggttatct tagtcgtctt gtttttgatt acttacttcc cgcaaatcgt catgtggcta
    12961 cccaatatgc tgagttagga gaatagttat gttgaacatt acaattagag gacatgatct
    13021 ttccgaagtc caaacgatag aagatcttgc agaaaaaaca aaagaacaag ggattcatac
    13081 actgcagctc gccttaggtc tttcgtttcc tgaaacacct tctggcgcaa atgagatcaa
    13141 ttctgggatg ggaaattatg tcaaacgagt tttagaaaag caagaagtga ccgtaggaat
    13201 tttaagttgc tatatcaata tgattcatcc agatttaacg atacgacaag agttgctgac
    13261 aaagttcgag cagtatcttc gctatgcttc ttcctttggt gcgtcgatgg ttgcttcgga
    13321 aactggatgt gttttgccgg aaatccaata tacggaagaa aatttcacag atgaagcatt
    13381 tgctgaagct gtgtccgtta tccgtcgctt ggtaaaagct ggagaaaaat accaaatgat
    13441 ggtggggata gaaccaggtt tgaatcatcc ggtgtattct ttagcaaggg tagagcagct
    13501 gatccaagca gtagattcgg actatctagg aatcatttta gatccgacca atttgatcac
    13561 aagtagtgat tatcaagaac aagtccaatt ggtagaagaa gcttttgaac gttttggtga
    13621 aaagatatgt gcggttcatt tgaaagattt tcgtgtcgaa caggaaaaaa tcgtgccggt
    13681 aaatttggga gacggtgtga tcgagtacac aaaaatcaaa gaaatcatca tgaagaatcg
    13741 tccgtacctg tatgtggttc ttgaagaaac aaaagatgat gggattcgtt atggaagaag
    13801 tcttcttgaa taatgtaaag aagacgttgg ttaactaata tttagaatgg agggggcggg
    13861 gctagaagat gccacgtctc ttctttttta taagagtata taaaagcagc tctttttgat
    13921 tacaaaaaac gtggtataat aaaattgtgc ataagtgaac aaaaggaggt gcggcacatg
    13981 ctccaaaaga aaatcagcgg tgaacaagtc aatacgatgg tttctgatca gtatgaaatc
    14041 tatcatgtca aagatgtcgt cagccaaaat aaaacgatct atcatcatca tgatttctat
    14101 gagatccatg ctacattaaa gggagaagcg actttttatt tgaacggacg acaatttacg
    14161 atcaaagcag gaagtgtgct gctcatccat tccaatgatt tgcatcgtat cgtccgccaa
    14221 tcttcagatg tattcgagcg tgtctatatc tttgtcaccc cttcttttct agaaagtcgt
    14281 tccacgccat ggtctaatct atcggcttgt tttcaaccaa tgggagagaa gaggagtcgt
    14341 gtattgcaaa tagaacagga agtattgaag caaaaattat catttatcga ccatcctcct
    14401 gataaaaaaa tttacggtga agacataaaa tatgaacaag ctctggtaga atacttgatt
    14461 tttctcaatc aagttgtaca aaaagaagag agtgcgcaag aacagaatgc tgtagttcct
    14521 aatgagcgtg tggaacaaat gttacaatat atctcaaaaa atttatctca tccgctttct
    14581 ttagaggaaa tggaaaagca gttttttgtc agcaaatacc atatcacacg agaatttaaa
    14641 aagtacactg gatttacgtt tcatcagtat gtaatgaaga aaaagctgat ctatgccaag
    14701 cacttgttgc gagaataccg cagctctagt gctgtatata gtaaaagtgg tttttcttct
    14761 tatccgcatt ttctgaaagc attcaagaga gagttcggca taacgcctaa agaatttttg
    14821 aaacgtgata cacagaaaca gttggttcat tatgaacatt ttgaagatga acaatgagaa
    14881 tgatcactaa aaaataaccg cagtagctgc tgttgtttac atagaagcag aaactgcggt
    14941 tattttattt ttatctatat atttcaaaat attttgaaaa aatgacgtac atattatatg
    15001 aatcagctga atttacgaaa gtctctcggc gatagtcctg tttttgcttt gaacaggcgg
    15061 ctaaagtaag caaaattctc aatccctatt tcttcggaaa tcattcgaac cgtaaattct
    15121 gtataccgaa gaaggtcttt agcgtaagaa agttttttgc tgatcaaata atcgattggt
    15181 ggagaaccga taaatttgga aaaatctttg ctcagctgat atttattcaa taagaattgt
    15241 tgttctaatt gatcaagtgt aatcgtttct ttgaaatgtt cgtctaagta ttgcttcagt
    15301 ttgtaaacgt aggcgggaat atcctcttct tcgaaatcta gctgatactt ttgcaaaatc
    15361 agttcattca gcaactcgtg gatagctaca gaggactgga aatcggtacg ggcattcgtg
    15421 ccttgttgca tgtggatcaa ttctgtgatc aaatggtgga tcttgttttc tgatggatcc
    15481 cctgttgaat ggaaggtgtt atggccgtct tttgtgaact cctgataaaa tgattggacg
    15541 ttctgaccat tcaaatggat ccaatccatt tcccatggtt cttcgctgat cgtttgataa
    15601 cgctgatatt cttggcagtc aataaaaaat aagtctccag cttttagctg ttgctgatta
    15661 tcattatatg taagcgaacc tttgccagac aaagtaaact ttatcaagta agaaggtaaa
    15721 tgtgctcgtt cagtatagta agggattggt gctttgaagt aaccgatttc ttggatataa
    15781 aaaaataaat tcctgcttct ttgtgtaggc gtcaagatca ctctttttga gtcttccgac
    15841 catgagtggt tggctttttc ccagtaatcc atgtaaacac tcccaacttg tcaagataat
    15901 gcaattatat accaaaatag tgtgaagcaa aatataagat tctgtattat gatagcattg
    15961 ttaataaatg ataacgcttt attaataaag tgctaatcaa caataaagta aaagaggtgg
    16021 agaaatgaat ccaacatttg ttgccatcga tatcggtgca tcaagcggac gactaatgaa
    16081 aagtacgagg gatgcaaaag gttctttgat cttggaagaa gtacaccggt tcaaaaacgg
    16141 ctttcggaac aaagacggtc acgatcgctg gaagatcgat tatcttatca aagagatttt
    16201 gattggattt gaaaaattaa agcagacagg gattgatcgc ctttttgcgg ggatcgatac
    16261 atgggcagtc gattactgtc tgattgatga acaaggggat cggataaatg atccgattgc
    16321 ttatcgggac aagcgtacca atggagcagt agaacagttt tctgaaatct attctctaga
    16381 taagttgtat gagcagacag ggattcagat ccagcctttc aataccttgt tccaattgtt
    16441 tgctgaagaa aaagaaaatt tggcaaaagc acataaattg ttactgatac ctgattattt
    16501 agggtatgtc tttactggta acatggtgac ggagaaaact aatgcatcta ctatgcagct
    16561 gctgaatgca gggacaaaag aatgggaaat agaacttctt gaaaaaatcg gtgtctcgaa
    16621 ggaattattt ccaccattga cagagccggg aacgatacta ggagatctgc aaaaagaaca
    16681 attttcaaaa tatgatttgc cagatgtgac ctttatcaca gtagcaagtc atgatacggc
    16741 gtcagctgta ttaggaacgc caggtcaagg agaacgttgg ggttatatca gcagtgggac
    16801 atggtcgctt ttagggattg aaacaaagat cgccaatgtt tctcgcaatg ctttttctga
    16861 aaattatacg aatgaatggg gtgcccataa cacggtgcgt tttttgaaaa acatcatggg
    16921 gatgtggttg atccaggaag ttgcccgaat gcaagagtac gagtacagtt atgcggaatt
    16981 ggcagagctt gctgcaaaag aaaaaccgct gcagcaagtg atggaaatca atgaccctcg
    17041 atttttgaat cccccaaata tgatagaaga gattcagcaa tactgttttg aaacagagca
    17101 gccagtccct gtctcatcgg gagctatcgc tcgttgtgtg tatgataatc ttgctctttg
    17161 ttacgcacaa gagctgatca aagtagaaca cttaactgga acgaaattgg aaaagctgca
    17221 catcgtaggg ggcggatcga ataatcgtct actgaatcaa ttgacagcag attatgccgg
    17281 aatcattgta gaagcaggac ctagtgaagc cacagcaatc gggaatgttg ccatgcaaat
    17341 gctcagtaca ggtcagtttt cgaatataga acaagcaaga aatgtaatca aacagtcgtt
    17401 tccatgtgaa actttttacc cagatgaaaa taagcaaaac acgatggaat ggtacgtgaa
    17461 taaaatcaaa ggagtaatcg tatgaacacg attgaaagaa attacgaaca agcaaaagaa
    17521 aaatatgcaa ctatcggtgt agatacagat gctgtactag aaaagataca ggacatcaaa
    17581 atttctatgc attgctggca aggagatgat gtcaaaggtt tcttgacacc ggatggcgaa
    17641 ttgaccggtg gaatcatggc gacagggaat tttccaggag ccgcacgaac acctgaagag
    17701 cttagacaag atctggagaa ggcttattcg ttgataccgg gcaaacacaa attgaacctt
    17761 catgctatct atttggatac agaagaatct gtcgatctaa atgaaattga gccgaaacat
    17821 tttgaaaaat gggtagagtg ggcaaaaaaa gaagaaatcg gtcttgactt caatccgact
    17881 ttcttttcgc atccaatgat gaaagacggc tttacattgg ctcatccaga taaagaagtt
    17941 cgtgaatact ggatcgaaca cgggaaaaga agccgcaaaa tcgcggagta ctttgggaaa
    18001 gaaactgggc aaacaagtat caataacttt tgggtacctg atgggatgaa agataatccg
    18061 attgatcgtt ttaccccacg ggaacgttta atggaatcac tcgatgaaat ttttacagaa
    18121 gagttagatg aacggtatgt acaagatgca gtagaaagca aactatttgg tttaggcgct
    18181 gaagcttata cagtcggttc ccatgaattt tatatgggtt acgggttgac tcgtgacaaa
    18241 cttgtttgtc tagatgctgg acattttcat ccaacagaag tgatttccaa taaattatct
    18301 tcattagctt tattcagcaa aggaatcatg ttgcatgttt cccgtccagt gcgttgggat
    18361 tcagaccatg tggttttgat ggatgatgaa ttgcaggaaa tcgctaaaga attagtccgt
    18421 aacgaattgt tggaaaaaac aaatatcggt ctggatttct ttgatgcaac gatcaaccgt
    18481 atcgctgctt gggtcatcgg tacgagaaat acacaaaaag cactgctgaa agctatgctg
    18541 gaaccagttg agcgattgaa agaaatggag ctggcttttg actttacttc aagaatggct
    18601 tatacggaag aattgaaaga tttcccgtat gccgatgtat ggaattattt ctgttacaaa
    18661 aatcaagttc cagttggttt ggattggctg gaagaagtcc aggaatatca aaaagacgtg
    18721 ttggaattaa gaaaatagga gtgtggctat attgaaaaaa atagatattt tacaagcgcc
    18781 ttatgtgaaa gaaatgatcg aaacgacgtc gaatctttat cgcttgggat gggatgaaag
    18841 aaatggcggg aatatttctt atttactaaa agaagaagag atcacaccgt tcttggatcc
    18901 tgaaaaagtg atccgccgca tctcgatgat ttttgatgcc agccgtttag caggatgcta
    18961 ttttattgta actggttcag gaagatattt taaaaatgta gcgagcgaac ctgccgagaa
    19021 tcttggaatc gttcgagttg ctgaagatgg caaaacactg gaacttttgt gggggctgga
    19081 aaacgaatgc cttcctacaa gcgagttgcc aagtcatttc atgagtcata tcgcccgttt
    19141 agaagtagac ccagataatc ggatcgttat gcattgccat gctagtcatc tattagcgat
    19201 gagttttacg catgaattag acgaacgttc ctttagtcgt acgctatggc aaatgtgtac
    19261 ggaatgctta gttgtttttc cagaaggaat ttccatcatt ccgtggatgg ttccgggaac
    19321 aaatgagatt ggggaagcaa cagctgaaaa aatgaaagaa actcgattgg ttttatggcc
    19381 acaacatgga atctacgggt caggaaaaga catggatgaa gtctttggtt tgatcgagac
    19441 agcagaaaag gcagcagaag tctatacgta cgtcaaagcg caaggaccaa tcttgcaaac
    19501 aatcacggac gaaaacctgt ggcatttagc agatgcgttt ggtgtcactc caaaagcagg
    19561 ttatttggag gaagttcata cgaaagcagg tgtctgacat ggtgaaaaaa gctttttgca
    19621 tgaaagttta cccagaaaaa caagaagaat acaaaaaaag acatgatgaa ctttggccag
    19681 aaatgcgtac agcacttcgt gaacacgggg tcatcgacta ttcgatctat cttgatccga
    19741 gtacaagttt gttatttggt tacttagtga tcgaagatga aaagttatgg gaaaaaatgg
    19801 caaatacatc tatcaatcaa aaatggtgga agtacatgga agatatcatg gagacaaatc
    19861 cagatgcctc tccagtcagt tgggaattga tgccagtctt tgaactgtag caacaagcaa
    19921 ctgggcaacc ggttgcttgg ggttctttcg tttttattgt gaaaaaaaat acaaattagg
    19981 aggaatagaa aatgagtaat cgaatgattt taaatgaaac atcgtatttt ggaaaaggag
    20041 cgattgagtc gatcgtccct gaatttcagc agcgaggatt cggcaaagca gctgtcatta
    20101 ctgacaaagg attgatcgag cacggtatag caacaaaagt aacagaactt ctagataaag
    20161 cagcaatcgc ttatgcttta tacgacggga tcgtacctaa tccaacgatc caaaatgtaa
    20221 aagatggagt ggcttttgtt aaagaggcag aggcagactg tttgatcgca atcggtggag
    20281 gttcgccaat cgatacggca aaagccattg ggattatttt gacgaatcca gagttttcag
    20341 acgtcattag tttagaaggt gttgctgata cgaaaaatcc atgtttacct atattagcta
    20401 taccaacgac ttctggaaca gcagcagaag taacgatcaa ctacgtcatc acagatgaag
    20461 taaatcaccg aaaatttgtt tgtgttgatc ctcatgatat cccaatcgtc gcgttcatcg
    20521 acagcgatat gatgatggga atgccgaaaa aattggctgc atcaacaggt atggatgcta
    20581 tgacgcatgc tattgaaggg tttatcacaa aaggcgcttg ggaaatgact gatatgctgc
    20641 atttaaaagc aatcgaaatc atcggccatt ctttggaagt ttctgtagat ggcgatcaaa
    20701 atgggcgaga aaaaatggca ttaggacagt atattgcggg aatgggcttc tcaaatgtcg
    20761 gtttaggact ggtacacggg atggctcacc cgttaagtgc atggtacaac attcctcatg
    20821 gcgtagcgtg tgcagcactt ttgccaactg tcatgaaata taacaaagaa tatactggag
    20881 aaaagtaccg tgagatcgct cttgttctag ggattaaagg agcagctgaa atgtctttag
    20941 aagatgtaag agaagcggct tgtggtgaga tcgatcggtt gagcaaagcg gttggaatcc
    21001 cagaaaccat ttctgaatta ggtgtaaaag aagcagatat tccagcaatt gcagaagatg
    21061 ctttgcgaga tgtatgcaca ccaggaaatc caagagaaac gacagtagaa gaaatcattg
    21121 ctttatatca aagtttgatg taaaaacgaa gcggatcttc aacattaaat tgcctgtaaa
    21181 gagaaatggt agtttatatc tggatatctc ttttaaattg atggtatttc cgctataatt
    21241 tttcttataa agaaatagga gaatattata tggaaaataa aaagccttat ggaactgtat
    21301 tgatcaaagc ctctaaaata ctagactatt tagcggaaaa ccaagatgtc tctttgcaga
    21361 cgatcgcaaa gggtgtggga atgacctctt ctacagtctt gaaaatacta gatactttgt
    21421 tgatgatcgg ctacgtaaat aaaaattcag agaaaaacta tcgtttaggt gcaaagctta
    21481 ttcgctacgc gaataaaaac attgaacaaa tcgatttggt agagttgact ttaccgtttt
    21541 tagaacagct gcagcaaaag atcgatgaga ctatccactt aggggtattg gacaacaatg
    21601 agatcttgta cgtgaacaaa ctagatccaa aacatcaaac gatccgcatg tcttcaaaaa
    21661 tcggaatcac ccgaccatta tacaattctg cgatgggcaa agccgtatta gcagaattca
    21721 gtgaagagca gtacactgat tatcttgaaa agcatccgtt gatcccttac acagaatata
    21781 cgatcaccaa tgcattacgg ttgaaaaagg aaatccaaac ggtaaaagaa acccacatcg
    21841 catttgacga tgaagaaatc gaacgtgata ttttttgtat aggagcctca atcgtgaaaa
    21901 acgaacaaat cattggtgca tttagtgtaa gtatgccgaa atatcgttta acagatgaga
    21961 caaaagaaca aataatcagt gccctcaagc aaacaaaaag cgaaatcgag caaagaattc
    22021 aaaaataatg aaaaaagcgt ttgcaatttt tcttttctgc cgtataatat gggtatagat
    22081 ttccaagtta taaaataaaa tttctaaata ggaaataggt ggagaagatg aaaaaaattg
    22141 atattttatc tcgattgaaa aacgccggag tgattgcggt ggtacgcgga aaaagcaaag
    22201 aagaagcttt gaatgcttgc cacgcaatca tcaaaggtgg tctaactggt attgagttga
    22261 cttttacagt ccctcaagca gatcaagtaa tcaaagaact tttgtcattc tacaaagacc
    22321 aaccagaaat agtgattggc gcaggcacag tattagacgc tgtcacagct cgcttggcta
    22381 tcttagctgg cgcagagtat attgttagcc cttcctttga tcaagaaacg gcagagatgt
    22441 gcaatctgta tcaaattcct tacttaccag gatgtatgac tattaccgag atcaaaacag
    22501 cgctgaaaag cggggtagat atcgtcaaac tatttcctgg aagcgcttat ggaccaagta
    22561 tcatttctgc cttcaaggcg ccgatgcctc aagtcaatat catgccaact ggcggtgtga
    22621 gtctggacaa tatgaaagag tggttcgatg ctggtgtcgt aacagtcgga gtaggtggga
    22681 accttttagc acccgcagct acaggagatt ttgacaaagt aacggaagtc gcgcaacagt
    22741 atgcagcaaa aatgaaagaa atcaagaggt agctgcttat gggaaaagta gtgacactcg
    22801 gagaaatcat gttgcgattg tccacagagc agggaacccg tatcgattca agtgaacgat
    22861 tcgctgccca ttatggcgga ggggaagcaa acgtagcaat ttctttagct aattacggac
    22921 atgaagcgat ttttgctaca aaagtacctg ataacgcatt gggaaaagca gtcaaaaagc
    22981 acttgcaatg ttatggagta gatacgaaac aggtattatc tggtggatca agactaggta
    23041 cttattatat ggaaactggt agtggcgaac gcgccgcctc agtgatctat gatcgtgccg
    23101 gatcaagttt tgctgaaatg gatcatttgg aatggtcgct agaggagtta ttccaaggaa
    23161 tagatatatt tcatgtttca ggaatcaccc cagctttgtc taaaaaatgg caaaaaatga
    23221 cgaaacaggt gatagaagct gcaaaaaaag ctggctgcct gatcagcttc gatatcaact
    23281 atcgtggaaa attatggaca cagcaagaag ccagcgaagt aatccatcag cttttacctt
    23341 tagtagatat ctgctcagct ggaaaaatgg atgctcttta tttgttaggt atcgagaaag
    23401 cgccagaagc agaagaacaa cctctaattt attattatca aaaaatgcag gaaaagttcc
    23461 cgaatattca ggtgttttat tcgaccaagc gtaccgttca ttcagcaagt gaaaatgaat
    23521 tgaaggggac attgtggatg aaccatgaat atgtggaatc ccaagtccat agaatcaccc
    23581 caatcgtgga tcgagtaggt ggcggagatg cttttgcagg tggcgtgctc catgggattt
    23641 tatccaatat gtctccgcaa gaaatcattg attttgctac ggcagcttct gccttgaagc
    23701 atacgatcca tggggactgc aaccaattta gtcaagaaga agtcgcacaa tttttagcat
    23761 gcggctctgg aaaaatcatt cgatagaagg agtagaagaa aatgcaagaa atggaaacac
    23821 gttatacaca cagtccagaa gatatccgtc attattcaac ggaacaattg agaaaagaat
    23881 ttttagtaga aaaggtattt gaaccaggga aaatcagttt gacttatacg cacaacgatc
    23941 gaatgatctt tggtggagtg acacctactg aaaaagaatt agaaatcaca ttagacaaag
    24001 aactaggtgt tgattacttc ttagagcgtc gtgaactagg tgtgatcaat atcggtggac
    24061 caggattcat cgagatcgat gggcaaaaag aagaaatgaa aaaacaagac ggatactata
    24121 tcggaaaaga aacacgacat gttgtatttt cttctcaaga tgctgaaaac ccagctaaat
    24181 tctatattag ttctgttcca gctcatcata aatatccaaa tgtaaaaatc agtatcgacc
    24241 aagtaaaacc aatggagact ggtgaaggcc tgacactgaa tgaacgtaaa atctaccaat
    24301 acatccatcc aaatgtatgc gaaagctgtc aattacaaat gggttatacg attttagaac
    24361 caggaagcgc ttggaatacg atgccttgtc atacacatga acgtcgtatg gaagcttatg
    24421 tctactttga ttatgccaat gaagatacac gtgtgttcca catgatgggc aaaccagatg
    24481 aaacaaaaca tttagttgta gacaatgaac aagccattat ttcgccaagc tggtcgatcc
    24541 attcaggtgt aggtacaagc aattactcat tcatctgggc aatgtgcgga gaaaatatca
    24601 cctatacaga catggatatg gtgcaaatgg atcaattaaa ataagcataa gggagagaaa
    24661 atgatggaat ttagtatgga tatgtttcgt ttagatggaa aagtagcatt agtcaccggt
    24721 gctgtctatg gtattggatt tgagattgca cgctctttag ctacagcagg agcaaaaatc
    24781 gtatttaata acttgaatca agaatcagtt gatgaaggta tagcgcatta taaagaagca
    24841 ggcatcgatg caaaaggtta tgtctgcgat gtgaccgatg aagaagcggt tcaagcgatg
    24901 gttcaacaga tcaaagaaga tgtaggttca gttgatattc tagtcaacaa tgcagggatc
    24961 atcaaacgga caccgatgat cgaaatggat gcggcagact tccgccaagt aatcgacgtg
    25021 gatttaaatg ccccattcat cgtttcaaaa gcagttattc cggatatgat cgaaaaaggc
    25081 ggcggtaaaa tcatcaatat ctgctccatg atgagtgaat taggacgcga aacggtcagt
    25141 gcttatgctg cggcaaaagg cggattaaaa atgctgacga aaaacatcgc ttctgaatac
    25201 ggtcaataca atatccaatg taatggaatt ggaccaggtt atattgctac accgcaaact
    25261 gctccattac gcgaaacaca agaaaacggt gaacgtcatc cattcgatca atttatcgtt
    25321 ggacgtacgc cagcagcacg ctggggcgag ccaatcgatt tggctggacc atctgtcttc
    25381 ttggcttcta gcgcatctga tttcgttaac ggccatgtct tgtatgtgga cggaggcata
    25441 cttgcctata tcggaaaaca accttaaaag agctttagta cactgtttag tggagaggtt
    25501 gtgaaatcag cggattgaac gaataccgaa ggacagctga ttaaacatca tttattcgaa
    25561 aaaagaggct gggacagaag catttaactc caagaaataa gaaggaattc acgaaaattg
    25621 cttttcaaat ttttgtgaat ttcagcttat ttccgaagga gttgctttta cttccgccgt
    25681 ttgtacgtgt ttagagcgtg agacaaaagt gttctttact tttgtcccac gctcttttct
    25741 gtgcgtcttc catacttcac taagtcgatc cctcttgctt cgcaccaatc cttcactggt
    25801 ccggaaaaga tcagagattg ttggtgtagg gccgcggtat tcgttgcgcc gaccatagta
    25861 taaagcagac gaagctcttc ttgccattgc ttcatcagta taatagtttc ttctacgccg
    25921 tgattcatca gatgcgtcag tacggttcct gaagtaccca cggcatttgc gccgagacaa
    25981 agggctttaa atatgtcata ggcattgcgg atacctccgg aggctaggat ttccatagaa
    26041 gtgtctgctt catttgcttc aagcaatgaa gagactgtcg attgccccca gtcagctaaa
    26101 taactcagtt cccgcttgga gcgacgggcg ttttcgatct gggtgaagct tgttccgctt
    26161 cgaccgctga tatcaactgt atgaactcct aaagcagcta gatcattgag cgtttctctt
    26221 gtcatgccaa aaccgacttc ttttacgatg agggggacgt caatggctgt ttgagtttct
    26281 tgaataagta ctttccaatt ggtaaaatca cggtctccct caggcataac caactcttga
    26341 ggtgcattca aatgaatctg taaggcatct gcgtgaaaca atcggatagc ttctttggct
    26401 ctttcgacag aagtccctgc accgatgttg gcaatgattt tcccgtgagg atattcttgt
    26461 cgcataatcg tataagtatc ggctaaagaa gggactttca aggcagcgct gactgaacca
    26521 gtggcaatca tcaaatctgc ttctcttgcg acgattgcaa gatcttggtt gatttttttt
    26581 gttttttcgc ttccgccagt catcgcattg atataaaatg ggctgcttag tgtaaaccca
    26641 actgcctgtg tacttagatc gacatcagaa actgctattt gcggcaaagg gttatggatg
    26701 atccgtacga agtcaaattc gtttttttgt ttatcatgaa aggctttagc tagtgaaaca
    26761 tgttcgtctt ttcgattcat cggttttcct ttctttgatc gctatagaca tgtaacggca
    26821 gtggagtgat ttctgctttt tcccatgcac tcattaaagg aagaatgcca gatttctggt
    26881 caacaattac gattccgcaa tcgcccccac ctgcaccaga agattttgcg gctccttcat
    26941 actgttcagc taaattacac aatttgttca aagcaggcgt ttcgatgacg accccagtga
    27001 ttgcagataa atcatgcagt aattgtcggt tttttcgaat catctgttgg atcaacgtta
    27061 cattattttc tttaaaccct ttgatcattt cgttgacaca ttctgtacta ttttttaaga
    27121 aaagctgata agccaccatt ttatcttctc tcgaacggtg aacttgatcg accaaatcag
    27181 aagtagaggc agggctaccc gtccaaccaa tcaataaacg taaatcttca ggagcaatca
    27241 atggctcaat ggatagacct ggccaatcca gggcaagtaa ctcactgata gaatgctgag
    27301 tttcttgttc ttggagccaa ggatggtcga aggttgagaa agcgatccag ccaccataac
    27361 agctagcagc gatgtcgccg caggaaccat tatcttgaac tgctaaattg gctagtgctg
    27421 caatcttgaa aatctccaac tgagataaat tcaacgcgta aaaaacattc aaggctttga
    27481 ccgttgcaac ggtcacggca ccgctagaac ccaatccata tttccggcca tttgaactgt
    27541 ctaactcact tgttactttc agatcataaa aggataaaag aatgtttttt tcttgtgcat
    27601 acttttcagt caagcgaata gcagcaagga tataatgaaa aggattttcc cgaatatcta
    27661 aaactaattc tccgttgcgt cttgtccaac gtacaggcat cccactatat tgtgcagatt
    27721 ggatacttcc gacttttcgt gcagattcta cagtgactgt cacgaattga tcgactgcag
    27781 cgataactgc tggatggcct gtttcaacaa ctgcatattc tccggcaata tagagtttgc
    27841 ctggtgcaga tacttcaatc ataaaaatct ccctttattc aataatcgca attcctggac
    27901 cagcatgtgc agtaattact tgttctttgc taaataattt ggtaaatgtt tcttgtacct
    27961 cagataaatg gctgttttcc actaaaactt tgacattagg gccagcatcc atcgtaaagt
    28021 agcatggaat gccttgcttt ctcaattgtc gcaccgcatc catcgctttt aagctgtcag
    28081 gagaccagta agtgaatgga ggctgggcag ctaaagtcgt tccatgcatt tttagtccgt
    28141 ttctttccat cgtttctccg agaagttgga aatcttttgt tttgattgct tgtttcaatt
    28201 gatatagatc cccttcaacg gaatctaacc agccttgata aaaactggat gtttcgactg
    28261 tccgacgcat cccatttctg ctggacactt cttttttctg gtcgttgatc aaaacgaaaa
    28321 ccattgctaa atcgtcttcg aaagaatcgg aagggactgg cttagcgtaa gaacttaagt
    28381 cgtcatggcc tttttcccat tcgacgaaac caccgaaaat acttcggcaa gctgaaccag
    28441 acccgcgtcg agcaaatctt gaaagagaga gatcatctaa tccaagctta agagcagtat
    28501 tgcaagcgcc tgctaaagca gctagcccgc tggcagagga ggctaatcca gctgcggtag
    28561 gaacgaaatt ctgactgatt actgaagctt ttagtgagag gccggcttct ttacgaaaaa
    28621 ggtcaagaaa ctgactgact ttttttgttg ctttttcgtc ttgcaaggtg ccatctagat
    28681 aaaattcatc taccatatag ctatcagaaa agatgacttc tgtctctgta taaaatgcat
    28741 ccaatgttaa cgaaaggctg ttgttcattg gaaggatgag ttcttcattt ttcttacccc
    28801 aatatttgat tagagcaatg ttggtatatg cgcgtgcttt gcctttaaac ataggtatgt
    28861 actcctaatc cttgtatcca agtttcagca gcacccgcat cttcaagtgc ttgactgatt
    28921 tcttgggctt ttgtttttgt ttgtgctaat gcaatcatac agccaccgcg tccaccgcca
    28981 gttaatttgg cacccaatgc cccggtatct tttgctgttt ggatcaatag attaagaaaa
    29041 tcattgctga ttgtcagctt ttccagaagt gattgtgatt catccattgt ctgtgccaac
    29101 gtttctggtg aattttcaat gattgcttgt tttgcttgct tcgtcaagta tcctaatttt
    29161 tggatcattt gtccagtttc atgaggctgg gtttcaaaga ggtgagcgac atctttgacg
    29221 gcttctcttg tttgtccttt gattcctgta tcagcgacaa tcaaaaaagc atcgatgttc
    29281 aaagaaaagt agtcgaaagg atgccctttt gtaaaataaa tcggctgcaa gctgctagta
    29341 gcggctgcat cgattccact aggattaccg tgggcgattt tttccgaaag ctggacattt
    29401 tctaatagta tttcacgaga caaaggaaat gctaagtaat cataaaaagc acgagtgact
    29461 gctgtggcga ctgcagcgct tgatcccatt ccacgttcag caggaatcgt gctttcaatg
    29521 gtcagttgca agtttttttg gatgtcatgc tgttttttta agtgaatgaa taattttttg
    29581 atatttttta atgcatgagg agcttcggct aaatttcctg aatagtagga agaaaccagt
    29641 tgatcgtcca ttgcatccag ctcttcaagg aatgcggtga cttttgttgc atagaaagga
    29701 aaggcaatcg ctggttctcc ataaacaacc gcgtgctcgc ccatcaatat gatctttccg
    29761 cttgattctc cttggccata gtttgccata atctaactcc ttctcacgta aaagtgattt
    29821 ttaagcaaaa aataaagcgc ccaaaacgag ttgcgctgct tcacgaattt ttttgtccac
    29881 taagggtctc aaaaaacatt cctcctttat tttactaaaa ccatctcaga agtaaaacta
    29941 agaatacgtt ttctaaagaa aaaacacttt tttcttaaga attttttgac tttttttctt
    30001 ctttgactag aaaaaaatac aattgacact actagatatt gggggtatat ttaaaaaggt
    30061 tggagttaaa cacaatattt agtgatgaag tgagctggag gtaaatgagc gtgatcgttt
    30121 tagcaggtac aattggtgcc ggaaaatcaa gtttaacaga aatgatggct gaacactttg
    30181 atagtcaggc attttatgaa tcgattgatg ataatgaagt cttgccctta ttttatgcaa
    30241 accctgaaca gtatgctttt ttgctgcaaa tttatttttt gaataaacgt tttgcaagca
    30301 tcaaacaagc aatgaaagat gacaataatg tattggaccg ttcgatttat gaagattcac
    30361 tgcttttcca tctaaatgca gatctaggaa gagcaacaga aacagaagtt cgtgtgtatg
    30421 atgaactgct ggaaaacatg atggaagaac ttccctatgc tgcccataaa aaacatccgg
    30481 atttattagt tcatattcgt gtatcttttg atacgatgtt ggagcgtatc gaaaaacgtg
    30541 gtcgttcgta tgaacaattg tcctttgatc caagtctata cgattattac aaagaattga
    30601 acagacgtta cgatcaatgg tatgaagaat acaaagaaag tccaaaaatc caaatcgatg
    30661 gagaccgcta taattttgtg gaagatcctc aagcaaaaga agaagtcttg aaaatgatcg
    30721 aagaaaaatt agcagagatt cgccaaacca aagtagccat ttgatttaca gttgctcaaa
    30781 taaagggtaa acctttattt gagcgacttt tttctttata ctggaaacaa atgtcaggag
    30841 gatagagtat gcgggaaaaa cactatttta atcaagaccg taatttttgg atcaatgtac
    30901 agcaaaacga tgtgctagct gttaaaaact taaaagaaga atatggcatt agtgacgaga
    30961 tgctgactta ttctctagat aaaaatgaac gggcgcgcgt agagtacgat tcttttgatg
    31021 aagcgttact gcttgtatca aatgttccgc accagcaaaa agtcgataat cattatgaaa
    31081 ctagtcctat cgcttttatt ttaaaagaag acggtttgtt tacatttacc acgccgaata
    31141 ccgagtacgt gattcgacta attcgatcgc ttttggaacg aatgccagac atgagtgtat
    31201 acagtttatt gtttcgtaca ttgtttttga tttctgattc cttttttcct ttaatcgagg
    31261 aagtgaatag tgaacgtcag cggcttaatc tgaaattaag agaaaaaaca acgaacaaga
    31321 atctgctgca actttcagat ttagagatcg gtttggttta cttagttaca ggaacaaaac
    31381 aaaatgtagt acttttagaa caaatcaagg cattggctat ttatcgcaag ttgtcagaaa
    31441 aggaaaaaga agagttggac gatgcgctga tcgaagcacg acaagcagtt gaaatgacga
    31501 acttagcttc gcagatttta gaccagctct ctggcactta taataatttg ctgaataaca
    31561 acttgaatga cacgatgaaa tttttgacgg tctggtcgct gatcttgacc gttccaacta
    31621 ttgtgacagg attcttcgga atgaatctcc agttaccctt tacccattcc gttttcggat
    31681 ggggaatcgc cttgatcatc agtttggtct tatctatttg gatgcttatt gcactgtggc
    31741 ggcggattcg ttgatctagt ctttgatctg caaaccaagg gcttgggcga tcacaagtgc
    31801 ttgctcttgg ttgacgatta gtcccgccaa agaatcttga gataaagcga ttgctgtgaa
    31861 gaaattagtc gtaaagtcta atcccttcag agaagttcga aaccagttcg aaccggtcaa
    31921 ctgattgtca gacaaaaaaa ggtttttcca agtgacctca taaaattcgc tgtcttctaa
    31981 ttgacaatga tcgaaggaga cagctttcaa gtttgtacta ctaaaggaag ccatcgaagc
    32041 aatacaatca gtgaaagtac agtctcgaag ataactttcg gcaaaattcg tacctgttaa
    32101 tttacattga tgaaacacga cttggtggaa actgccacca atccactcca gattggaaaa
    32161 atcacatttt tcaaaaatga cattactgca ttcaaaatga cgtaaaactg ttttttgcat
    32221 cgtaagtttt tggatatgac tctctcttaa taccatattt ttggcatcga gatagctttg
    32281 gtcacccccg ttgatcagaa gaccagagaa gatctcctca tcttctaaat aaaactctcc
    32341 ctttgtaaga agaggaagag aaggtggaat aggttcgatt tttttcatgt gggttcacct
    32401 cgtttttctt tagtatagca aagaagcggg aatcactgct agaaagtctg ctaatctaat
    32461 cattttcaga aaaggaagac aaactgtatg aaaaacattg acaaaaagat tagtttttgc
    32521 tatactatga tggttgagaa ataaaagcag aagcacccgc ttctcgcctt agttgataat
    32581 gtcactgggc tagatagttt tcactggttc tattaggtga agtacgcgcg ggttctgtaa
    32641 gagaactcgt ttttttattg ccgtttattc ggtaagcttt tctttctctc ataatatttg
    32701 gaggtgaatg accatagcaa aggatatgat ggttaacgac ggcattcgtg cacgagagtt
    32761 acgattgatc ggttcagatg gtgagcaatt aggagttaag acaaaagcag aagcattgaa
    32821 tattgcagaa caagcaaact tggatcttgt gttagttgcc cctggtgcga aaccaccagt
    32881 tgcgcgaatc atggactacg gtaaataccg tttcgaacaa caaaagaaag accgcgaagc
    32941 gcgtaaaaaa caaaaagtga tcaatgtaaa agaagttcgc ttaagtccta cgatcgactt
    33001 gaatgacttc aatacaaaac ttcgtaatgc acgtaagttc ttggaaaagg gcgataaagt
    33061 gaaagcttct atccgtttca aaggccgtgc cattacccat aaagaaattg gtcaaaaagt
    33121 cttgaatcgc ttagctgaag aaactgcgga tattgcaaca gtggaacaaa aagcgaaaat
    33181 ggacggacgc agcatgttct tgacgctggc accgaaaaac gacagtaagt aatttgaatg
    33241 actaactggc tgttggacag ccgatagtcg gataacgaaa gattttgagg aggaaatata
    33301 gtcatgccaa aacaaaaaac acaccgcgga tcagcaaaac gtttcaaacg tactggtaaa
    33361 ggcggattga aacgcttccg cgcgtttaca agtcaccgtt tccacggcaa aacaaaaaaa
    33421 caacgccgtc aattgcgtaa agcaagcatg gtttctagtg gcgacttcaa acgtattcgc
    33481 caacaactag caaaaatgaa ataagaagta caaataacag aatctgaaga tttattttta
    33541 ttaggaggaa ttatacatgg cacgtgttaa aggtggaaca gtaactcgta aacgtcgtaa
    33601 aagagtgcta aaattagcaa aaggttacta cggttcaaaa cacactttat ttaaaacagc
    33661 aaaagaacaa gtaatgaatt catacaacta cgcatatcgc gatcgtcgtc aaaagaaacg
    33721 cgacttccgt aaattgtgga ttgctcgtat caacgcagca gctcgtatga atggcttgag
    33781 ctactcaaaa ttaatgcacg gtttgaaagt tgctgaaatc gacatcaacc gtaaaatgtt
    33841 agctgacttg gctgttaacg atgcagcagc atttactgca ttggctgacc aagcaaaaga
    33901 agctttggct aaataagcta aacaattata aagaggaaag aagataacga aaagttatgt
    33961 tctttcctct ttttttattt acaatcctcc atcaaatgaa acaggacaat aacgtataag
    34021 tctaaaatag cataattaag gttttttaat tgaaaactga acatttatgg tcacccttta
    34081 atgaaagcgc taactacata agttagaatg agtttgactg atatattagt ttgcttatca
    34141 gaaaaacaaa atggacggag gaataacatg agtgatatta ttattggtat tttgttagtt
    34201 atctcattct ttttcatggt ctggtactgt gtaaaaggct acaacttgat ggtcggcttt
    34261 gccatcatgg ctactgtatg gatgggatta gcgctagtcg gaaacacgtt ttcaccaaac
    34321 ccggcgatgg aagggcaagg agtaattgat gtgttgacgc atatctatac gacggggcca
    34381 gctgagtacg ccaaatcgat cttggtaaat gtcttctttg gtgccttttt cgggcgtgtt
    34441 ctagtagata gcggaatcgc agctaccctg attcgaaagg tagttgaact tggaggggac
    34501 aagccaagaa tcacgatgag cttactatgt attgtaaccg ctgttatatt catgtcgatg
    34561 acaggaatcg gaccagtgat ttctattgca gttattgtgt tgccaatctt gatgtcatta
    34621 ggtatttcag taccggttgc actgttctca tttatgggct cgattatggc tggaatcttt
    34681 gctaatatcg tcaatttcaa acaatatcaa acgatttatg ctggtttcaa tccagcggct
    34741 gaaagctata cttataatga ctatttccaa attggtatga ttgggatgat tgtaagctta
    34801 gttgtggtac taacggtcgc taatatatca atgaacaaaa agaaacgcta tgcaatggca
    34861 gcaaacgtac cagctgaagg tggcgacgca ccaatgatct catggttagc cgtattatta
    34921 ccagttttag gggtcgttct tttagatctt ccaatcatct taggttttat tctagcaggt
    34981 atctgggcat tgctgtttac tggaaaattg cgcggaggtt ataaagaaat ctgtcgtcag
    35041 tttgcgaaat tatttacaga tggcgcagta gatgttgcac caatggttgg tttcttgatg
    35101 accttagcga tgttcaataa ttcagctgcg tatgcttctc cttatttttc agctattttt
    35161 ggagattgga taccgcaatc accattagtc ttggcaatcg tatttgctat attgacacca
    35221 ctaggatttt tccgcggtcc aatgaatcta gtcggttcag gctcagctat tttagctgtc
    35281 gtattagctg ttaatccaac gatgtcgcca gcctttttgt tcccgttatt tgcaatcaca
    35341 acgattgctc ctcagcattt agatattaca caatcttggg ttgcttgggg attaggttat
    35401 acaaaagtaa cttctcgaga atatatgaag aaatccatcc caactggttg gatcatcgga
    35461 gcgatcttat gcctgatcac gttcttattg tacgggaacg cctagtaaac aaaacgtcga
    35521 taaaaacgat tagatgaatg gaggaaaaga aaatgaaacg ttttgtgcga atgggaattg
    35581 atgttggcgg tacacatacg aaagcagtcg caatcgataa tgcgacgcac gaaatcatcg
    35641 gaaaatcttc agtgaaaaca acccacgatg atgtccgtgg agtagccgca ggtgtcgttc
    35701 agtcttttca aaattgtttg cgggaaaata atatcagtcc agaagatgtt gtgtttgttg
    35761 cacattctac cacacaagcg actaatgcac tgattgaagg agacgtagca aaagtcggcg
    35821 taatcgggat ggcaaaaggt ggattagaag gttttttagc aaaacgacaa actagattga
    35881 acgatatcga tttagggaat aagaaaaaaa tagagattgt caatgcattc ttacctgtca
    35941 aacacttaaa tgtagaccgt gtttcagaaa cgatttcttc tttagaaaga gaaagagcgg
    36001 aggtcttggt ttcttctatg gcatttggag tagataatgg ggaaccagaa cgagttgttt
    36061 atgaagcagc atcggtaaaa tcgatcccta caacgatggc ttctgacatc acaaaattat
    36121 atggattgac aagaagaact cggacagcag caatcaatgc atctatttta ccaaaaatgc
    36181 tagatacggc aacctctaca gaagattccg tacgagaagc aggggtcaat gtttctttga
    36241 tgattatgcg cggagacggc ggagtaatgg aaatcaatga aatgaaaaaa cgacctgttt
    36301 taaccatgct ttccggtcca gcagcatcag tcatgggctc tttgatgtac ttgagagcgt
    36361 ctaatggtgt ttattttgaa gtaggcggaa caacaaccaa tatcggggtc attaaaaatg
    36421 gacgtccagc aatcgattat tcaattgtag gtggccaccc aacatatatc tcttcattag
    36481 atgttcgggt tctaggtgtg gcaggcggtt cgatggtacg ggctaatcag tcaggaatca
    36541 tcgatgtcgg tccacgttct gcacatattg ccggtctaga ttatgcagta tttacggaga
    36601 cagaaaaaat caaaggtcct aaggttgaat ttttctctcc taaagaagga gaccctgctg
    36661 attacgtcaa ggtagtgatg gaagacggag aagaagtgac tattacaaat acatgtgcag
    36721 ccaatgtcct tggattagtg caagaagaac atttttctta tggaaatgtc ccatctgcac
    36781 gaaaagccat ccaagcatta gctgattatt gtcatacgac ggttgaagac atcgcagaac
    36841 agatcatgga aaaatcctat gctaagattg aaccggtgat tttagaattg gcagacaagt
    36901 atcacttgga gaaagatcag atttctcttg taggtgtagg gggcggcgct gcctcattga
    36961 ttacttactt tagtaataaa atgggtgtga aatattcgat tcctgaaaac gccgaagtga
    37021 tttcttctat tggtgtagca cttgcaatgg tccgagatgt tgtagaacgt atcatccctt
    37081 cgccaagtaa agaagatata cgatcgttga aaaatgaagc gatgaataaa gcgattgaat
    37141 caggcgctac accagaatcg atcgaagtcc acgtagaaat cgatccacag acttcaaaag
    37201 taacggctat cgctactggt tctacggaag tgaaagcaac cgatctaacc aaggagatca
    37261 caacagaaga agcactagag cttgctgcag aggatatgcg attaaataaa aatgaagttt
    37321 gcttattgga aaatacacct ttcttttatg tatgcggcga acagaatcgt tcaaaaaatg
    37381 ctggaagtct tcggatcatc gatcaaaaag gatttatcaa ggtccaacgt ggacatgctt
    37441 catgtatgaa aacaactgca gccaattata tgacagctgt cgaacaactt tgggaagata
    37501 tggcagttta tcaaactgaa ttgattgccc gaccagaatt ttatctctgc ttaggagcaa
    37561 gagtctctga ttttacagcg acggatctgg aacaactaca gcttttgatg gatctggaag
    37621 tatctactat ggaaccggag gaagaagtga tcgtcgttgc cggaaatatc aaacaaacat
    37681 aagttagaag agttactaaa cgaattacaa cagatccccg aagaaatttg gggattctac
    37741 cagtttcggc gagatttatt ttggaaaaag attcctttgt ccaagcagaa aattcttata
    37801 caacaatcaa tcgattgtgg tatcgaaacg gcatgtagca tcaaaaaaaa gtaccctttt
    37861 gccgatgtag gagaaatttg tgaacaaatg gctgttccaa tcgtttcctg tgaatcagag
    37921 caaataaacg aacgaatcac ttttgcaact tatgcagaag atgaagggat tcgattgatg
    37981 acggagccgt tagaaaaatt aaaatgttca ggactagctt cgatctctaa agaaacagcg
    38041 caagctttga ttattggaca tgaactattt caccacatcg aagcttctgt taagggaatt
    38101 tatacgcaaa gcgaaaaaat tgtgctgtgg cggttgcctt tttatacaca tcaatcaaac
    38161 attcgtgcat tgagcgagat agcagcgatg agtttttcaa aagagatgaa tcaaagcgat
    38221 ttttcgcctt atgtattaga ggcagtctta ctttggccat ataatgaaat tcgtagccaa
    38281 gggatcttag aagaaataaa aaaaatagaa aaaagatgta cggagtatga tttagattac
    38341 aaataaagag actgtgacaa aagtcgtgtc acagtccttt ttttccgaat aaacgatgtt
    38401 ctcctgtcaa ctcctcggtc acaagtcaaa atattcaaca aacatgagaa gctgtttttt
    38461 gaaattgttc cttgtgactc ggagatgaac ggcaggctca cgacctcttg gaaaacggtg
    38521 ttcaaaagct tgcatctgcg gtaataagtc cagccaagtt aaaaacataa gaagctattt
    38581 ttacttggct gttcttatta cttgatgcag ggcagctttt tcacaacctc tcaataaacg
    38641 gtgtgcaatc agctgaccct cggtattagc tcaaaaaaaa cggcaaaata tgaggaacta
    38701 ttttgccgtt tctttctcta atactcaggt caaaacgctg attccaaaac ctcttatttg
    38761 atgggtctgt cctgaatatc ttcaaaataa tcggggtaat tatgaatcac gtattcttgc
    38821 tcctcgataa tcatatgtaa atgcatcgtg caaagaaatc cgacttcatc aaagttatga
    38881 tcaatcattg attgaagcat tgtctgatgt tcatctaata ctcgacccca gtctaattct
    38941 gaaatcgtca aacgtaacca tctgaaacgg ttcaagtgcg tactataact ttctagccaa
    39001 tcccaaattt ctcgttttcc agcaatttca taacaagttc ggtgaaaatc agtatccaaa
    39061 tcaaaaaaag cttttttatt ttgagcgatt actgcctgat cggtttttcc aacttttccc
    39121 gcgtataacg ggctaatgaa gcagatcgga tatcgatttt tgaaacataa gtgccggact
    39181 gtggaatggt ttttacaagc tcttgattgc gcagttggat cagtgcttct cgaatcggtg
    39241 tacgcccgat agctagttgt tcttctaaca ctttatcgga gattttactt ccaggtgcta
    39301 actcggaata aatgatttgt ttacgtatag attcataagc ttgctgttgc aaattattga
    39361 taaccattta accttccttt ctatgcagat ataatctatt ataacataaa tcgcttacaa
    39421 atcgtgtggg cataaaaaca cagtctgcaa aaaaagccct gataggcatg cctattagag
    39481 cctcgaaaag aaaaatattg aatcaatctg gtcgtacctc ttgtatcggt ttgacacgac
    39541 cgccgattct tttagcaaaa gcttcggatt cttttttgtc tttgaaaatg agcagattgt
    39601 ctaagttttt ttcccgagtg cgacagccag ttttatcgat gtaaccgtgc attactttaa
    39661 cgacatacat ggggatcacc tgcttttttc ttttcattat acgaactact cgacacaata
    39721 caagaaaaat gcttagacgg tctttattaa gaatttacat catccaaaga agcgtacgct
    39781 tggaataact gatctaactc cggattgact ttgctcagct tcactaatcg ttgcgaatca
    39841 gaaagtaaaa aacagtgttt actactgcca gtagttttta attttttgtc ttcagttccc
    39901 acaatttcgt agctaaaatc caaccgtgtc cccgtatact tttggatagt tggatggatg
    39961 ctcacttttt ctccgtaatg gatcatttct ttatagctgc aatttacttc cagaacgggg
    40021 atgatgatcc cagattcttc gattttttta tagggaaacc ctagatgtac caataaggct
    40081 acccgagcct cttcaaacca gcggatataa ttgctgtgat gaataatccc catttgatct
    40141 gtttcataat aaaaaggttc tcgcacataa cctgtaaatt tctccatgac tcatgcctcg
    40201 ttttccattg attttttaca aaaataattc atccatttcg gaagtgcttc gctgatttgt
    40261 gtcggcaaaa caatatattg ttcttttgcc agctggtctc caatgaaact atgaagataa
    40321 atagctgctg caatcgtttg gtcattttga ggaaactggg ctaaaaatcc tgtgatcatc
    40381 ccagctaaag tgtcacccat gccgcccgtt gccatagcag cagaacctaa aggattggtg
    40441 tagaagtgct ggtgaccata aatttttgtc tcatgacttt tcaaaacgag cacagcaccg
    40501 atttcctgtt gcttcttttt gttttcttta tcccgttgtt cttgtatcgg tagagaactc
    40561 aaccgttgcc actccatttg atgaggtgta agtacagttt gttcgggata gggtagcaaa
    40621 agatgattag cagcaagtaa acttaaagca gagccatcaa tcaccagcca ttgttctttt
    40681 gattggtttt ctagtacttg tttgaaacgt tccaaactct tagaagaagt acccaatccg
    40741 ggaccaatca agagtacatc tgcttgcttt attacggaaa gaaactggtc agtatccgtc
    40801 caaactacaa tcattgcttc tggcagatga ctgtgaagag cactccgatt tttttcatca
    40861 gttactacag tcgtgagacc cgctccgctg tgtacggcag ctaaagcact cataatgatt
    40921 gctccgccat attgttcatt gccgccaatc aaaacgatac gtccaaatgt tcctttatgt
    40981 gaaatttttg gacgaggtgt gatgactctt ttcactagtt gttcgtttat cagcatctaa
    41041 aaacctcctt ttactcatta tagcgtatat tttttttaga gaaaaacaga taagaaaagg
    41101 aattgtcaga ttttttgaac tatttttttc tgtaatttgt ggtatcatga acacgaagac
    41161 ttaaataagt ggaggattaa ctttatgaca attgattggc aaaaagaagt agaagcacgt
    41221 aaagaagact tgcttgaaga cttgaaaaat cttttacgtg tcaacagcga gcgcgatgac
    41281 tcaaaagtaa caccagatgc accatttgga cctggacctc gcgacgcatt gaaacatatg
    41341 ttagcttatg gcgaacgtga tggatttaaa gtaaaaaatg tcgataacta tgcagggcat
    41401 attgatcttg gcgaaggaga cgaaacgcta gggatatttg gacacatgga tgtcgttcct
    41461 gcaggagatg gctgggacac agatccttat gaaccagtaa tcaaggatgg aaagatcttt
    41521 gcacgcggat caagcgatga caaaggtcca agtatggcag cttactatgc gatgaagatc
    41581 attaaagaac ttgacttgaa actatcaaaa aaagttcgct tcgtagtcgg cagcgatgaa
    41641 gaaagcggct ggggcgatat ggcttattat ttcgaacatg aagaagaacc agattttggt
    41701 ttctcaccag atgctgaatt cccaatcatc aatggtgaaa aaggaaatgt ttctttagct
    41761 ttacgcttca aaggcgacaa tgcaggagat tatgtcttga aatcttttgt ttccggactt
    41821 cgcgaaaata tggtgccagg aacagcaact gcagcacttc aagtaccaag tgcagatgca
    41881 gctatcgcga tggaagaagc attttaccaa ttcatcgaag caaatccagt aagcggaacg
    41941 attgaagcgg acaatacgta tgtaaaaatc gaattagttg gtaaaggcgc acatggtgca
    42001 agcccacaat ctggtatcaa tgcaggttct ttcttggcat tgttcttaga taactatgaa
    42061 ttcctaggat ctgctaaaca atttatccat gtagcagctg cttatgtcca tgaagatttt
    42121 tatggagaaa aactaggagt cgcttatgaa gatgaaaaaa tgggcaaatt gacaatgaat
    42181 gctggactat ttgcttttga agaaaatggt acagaggaag cgaacttcat caatatgaat
    42241 ttccgttttc caaaaggtgt aacagtagac ggattgcaaa gtgacatcga acaaacagtg
    42301 gggcaagaag gcgcaacagt tactcgaggt gctcgcgtaa tggaaccaca ttacgtacca
    42361 atggatgatc cattggtggc tacattattg caagtctatg aagaccacac tggagaaaaa
    42421 ggctacgaac aaatcatcgg tggcggaact tacggacgtt tgttgaaacg tggcgttgct
    42481 tatggagcga tgttcccagg atatactgat acaatgcatc aagcaaacga atttatgagt
    42541 cttgatgact tgttcagagc aacagcaatc tatgcagatg ccatctatcg tttggcgaaa
    42601 taattaatta aaaagaggat caagaattgc aaattatttt tgcagtcttg atcctttttt
    42661 tactttctac tgtggtattc atgataaaca tgatatagat tcaattcata ttctttctta
    42721 gcgttcgtga cgactgtatc caaaatcaac cctgttacta atgaaagaag tgctaaagtc
    42781 atcaatccag tacttaaaat cgcagaaggg atgcgtgtaa taaagcttgt cagcatatat
    42841 tcgcgaatca caggaatccc cgtgaccaat ccaaataaaa agaagaagat ggtccaaatc
    42901 ccaaagaaaa gcaaaggctt ataatcttta aacattttaa taatcatcat gatcactttg
    42961 aatccgtcag agaatgtatt caattttgat tcgctgcctt caggacgatc acgataatcg
    43021 attgggattt caacgaactt gaatttttta tctaaagcat ggatcgtcaa ttccgtttcg
    43081 atttgaaaac cagaactcat aataggaaaa cttttgacaa agatacgatt gaatcctcga
    43141 tagccggtca tgacatcaag aatttttgtt ttatacattc tagtaattgt atttctaaca
    43201 aggttatttc caaaatcgtg gaaaggtctc ttattctcat caaagtaggt tccatttgat
    43261 aggcgatcac caatgaccat atctgcttca ccagaacgta atttctcgag caaaccatgt
    43321 acagcttctg caggataagt atcatcgcca tctaccatta aataatagtc ggcatcgata
    43381 tcaaagaaca tttggcggat cacatttcct tttccttgac gaggttcttt ttttacgatt
    43441 gctccacctt gaacggccaa ttcgtatgtt cgatcggtcg aattattatc atagacataa
    43501 atatctgctt ctggtaattc tcgtttaaag tctgcaatga ctgttgaaat tgttgcttcc
    43561 tcattgtaac aaggaatcag aacagcaatt ttttcttgtt gttccatttt tcactctcct
    43621 taactataga aaacaaaagc taaattaaaa atacctcata atcaaaggaa atgctagttt
    43681 ttcccgctaa atatcattta tttaaaaaga aaatactgga atatatgttt ggaaagctct
    43741 atctaaaaaa ccacccacta caaaagaagg acatgatacc tctcttttga atagtgggtg
    43801 cgtattcgtt ctctcacttt tttgacgtat taatctgttg cacctttttt tcttgaaatt
    43861 tctaatacgg ttcctgtatg agcatctgct aaaaattcat aataaacagt ttcgccatct
    43921 tctattcgag aaagacctcc ccgataagca ctcgaccgaa cggcgaattt cctaataggt
    43981 tccttttcaa aagagatcca agaaccttcg attgcacctt cttttagaaa agatgacttg
    44041 atattttcaa gtacttggtc tgctgacaat acttttttgc gatgatacca aatcgttgaa
    44101 gctaccccgc tcaataatcc tagaccgatt ccaactgcta acccgccttt aaaatagctt
    44161 agttcgcttt cttcatacat gtggacatac ctccttcttc tcacttgtta ctccttgtgc
    44221 ttattttacc acactctcat attttctttg aaataaataa ccgctaccag aaaaaataag
    44281 ctataataaa tacgatcggt ctgcagaaaa aatcatattt tatccgcaga tcaatataag
    44341 tctgagagga gtttagtctg aaatttagac gaatagcata tggaagaaaa aacatttcaa
    44401 cgaatcaaag agttaacaga attacaagga acaagcggtt ttgaacaaga tgttcgcgct
    44461 tatatggaaa gtcatatgga accgctggta gatgagttac agttagatgg tttgggcggc
    44521 atttttggtc tgcgccatca tgaagaagcg gatgcacccc gtgtaatggt cgcagcacat
    44581 atggatgaag tcggattcat gctgacacaa atccaagaaa acgggctttt taaagtcgta
    44641 cctctaggcg gctggaatcc ttacgttgtt tctgctcagc gttttacact taaaacctct
    44701 actggtaaga attatccatg tatttcttct tccgttcccc cacatttatt gcgaggaaca
    44761 agcggacaaa aatcagtaga agtaaccgat attttgttcg atgctgggtt tgaatcaaga
    44821 gaagaggcaa tgagttacgg tgtccttcca ggagacacaa tcgttcctta cgctgaaacg
    44881 atcaaaacag ccaacggaaa gaatattatc agtaaatcat gggacaaccg ctatggctgt
    44941 acaatggtat tagaagcttt agaagcgttg caaaatgaaa cattaggtca tacattgatt
    45001 gcaggcgcga atgtccagga agaagtaggc ttgcgtggtt ctaaagcttc tgtcaataaa
    45061 ttcaagccag atctgttctt tgcagtagac tgctctgcag cagatgatac agtgacgaaa
    45121 aatggcacat tcggacattt aggagaaggt acattgatgc gtatccaaga tccaggtttg
    45181 atcatgcttc ctcgtttgcg cgagtacttg ctggatatcg ctgaaacaaa caatatccct
    45241 tatcaatact ttgtttcaaa aggcggtaca gatgcaggtg ctgctcatac acaaaacgaa
    45301 ggaatcccaa gtacagtgat tggcgtagtg ggacgttata tccatacgca tcaaacgatg
    45361 ttcagtattc gcgattttga agctgcacga gaaatgttga ttcaaacact gaaaggtttg
    45421 gataaatcaa cagtgaatac gatcgtatac ggaaaataat gcgatagtga aactataaaa
    45481 tctggcaaaa gattgctttt tgccagattt tttttataaa aagaggatca atgtttgtta
    45541 gttcgaaaga aaggtgtata atttaattga aaaatacata aacagaaagt agaggacaaa
    45601 gaatgattat cccaaatagt ttagaagaat tagcaggcta cgtagaaact ggaaagagtg
    45661 tatttttctt tactgccggc tggtgcggag actgccgttt tatcaaaccg caaatgcctg
    45721 aaattgaaaa tgacttttct gattggcaat ttattgaagt agaccgtgac aagtacatag
    45781 atgtagccgc tgaatggaac atttttggta tcccaagttt tgtcgtgatc caagacggaa
    45841 aagaattagg tcgtctagtg aataaagatc gtaaaacaaa acaggaaatc gaatcgttcc
    45901 tagaaagtgt aacaaaaggc tgacatctgt taggaggggt caagatgaat caagaatata
    45961 agaatatttt agtaggtatc gacggtagtg aacaagcact tgctgctttc aaaaaagcgg
    46021 tagaagtggc tcgccgtaat aatgggaaag tatatgtagc aaacgtaatc gatcagcaat
    46081 tttataactt tatgggctat gcacctattg atcaaaatct agtcgatcag caaactgaaa
    46141 cagccaagga aatgatcgaa gaatgtaaag aatatgggaa atctgttgat tacacaaata
    46201 tagaaggaat tattgcatat ggttctgttc gtgaatccat ggcagtcaaa ttgccaaaaa
    46261 aatatgagat cgatctaatc atggttgggc agtcaggtct aaatgcagtc gaacgcttta
    46321 tgacaggaag tgtagccagc tacgtgatac gtcattcacc ttgtgatgtc ttgatcgttt
    46381 ctgacgaaga agaacagcca agtaattaag caagtggaac ttgtacgacc tttttaatca
    46441 attaactaaa acagtaaagg gactgtgaca aaagtcttgt cacagtccct tgttacgaat
    46501 aaatggtgtt ccagaagagg cttcttcgga aataaagcat gaaaaaaatt tcatgcagtg
    46561 aatgcaattt tttgttaaga taaatctcag caaaggataa tggaggaaag aacatgattt
    46621 ttgcttataa caaagcacac gtcggagaca ccttgatggt tattatagcc gacgataaag
    46681 gaacagaaaa cactgttgaa cgcaaatgga atgttgctcg gatcaaagat gaacaaggtc
    46741 aagttgttgc ttggaacttt ttccatatct ccgatcatct aacaatcgaa gggaacggcc
    46801 aagtaagctt aacagatgag gaattagcga aattgaatcg attgatcaaa gaagcaggat
    46861 tcgaagaaca gcttgaagct gatcatgaac cgaagatcgt tgtcgggtac gtaaaaacat
    46921 gcgtcccaca tcctgattct gaccatttat cgattactga gacagaagta gacaatggta
    46981 cagtattgca aatcgtttgc ggtgcaccca atatcgaagc tggacaaaaa gttgtcgttg
    47041 caaaaccagg agctatgatg ccagatggaa tgatgatctg gccaggaact ttgcgagggg
    47101 tagatagcta tggaatgatc tgttccgctc gtgaattgca tttgccaaat gctccagcaa
    47161 aaaaaggaat cttagtattg cctgaggatg ccgtagtcgg agaagcattt ccaaaataaa
    47221 gaggttgtga caagtctttg tcacaacctc ttttttatta attttcacta ttttgatttt
    47281 gttttaatgc cgattgatcg atcgtcaatt caacagtagt tgttttttct ttcgagcctt
    47341 catagtaagt gattttgaca gaatctccca cttttttctt atacaaagca gattgaagtt
    47401 ctacaccaga agaaacttct ttgtcatcga tcttagtaat gacgtcgtat tgtttcaatc
    47461 cagctttttc agccggtgta gctgtttgga catttgtcac gatgacaccg ttagttacag
    47521 atgaaggaat cttcaagatt tgttcttgtt gctgagtaga aacggcagat aagtcgacca
    47581 ttgtgatacc tagagctgga cgtgtcactt ttccgtcttt ttccagttga ttgatgatat
    47641 tcactacatc gttacttgga atagcaaatc ccattccttc tacgcttaca ttagaagtag
    47701 attcagaagt acttgcgatc ttacttgagt tgataccgat aacttgtcct tcgatattaa
    47761 ctaaaggacc accagaattt ccagggttga ttgctgcatc tgtttggatc gcattgatat
    47821 tgactgtttc gttcgattca ttcgtacttg tcacttgtcg gttcaaggaa gaaatgattc
    47881 ctgaagtgac agaatttgca tattcagatc ctagtgggga accaatcgca atcgcaggct
    47941 caccaacctt cagagcactt gagtcaccaa aagaggcaac tgtttcgact ttgtctgaat
    48001 tgatcttcaa caccgctaaa tctgaataag catctgttcc aactaattca gcttttacct
    48061 tcgtaccgtc tttcatcaag acttcaagac cttgctggcc atctactacg tgattattcg
    48121 tgactacata agcagtattc ccgtcttttt tgtagatcac gccgcttcct tcactataag
    48181 cttccaaatt actatcatct gagctgctac tttcttcttg ctgcccgaat agtccgccaa
    48241 aaccgcttga ttggttttga ctttgtaagt tgataacaga aacgacagcg tcttgaactt
    48301 tatctaccgc tttggtgata tcagaatcta cattgacttt gacattttcc acaactgttt
    48361 caccggcaga attctgattg ccgcttgtag cagtagaact attgttgcca gtgcccatcg
    48421 ctgcataaaa aatgccagct gtcagtagtc ctccaacgat ccctccaaca agccccagac
    48481 ctaacttacg ccagaggcta ttatttttac tttttttcat ctttggtgtc acattttttc
    48541 tatccatgtg ttcctcctcc aattacattc atttatctac tgttagtata gtcttatttg
    48601 ttgactttag tctactttga gactgtgaac tttttatgaa aaactttagg aaaaatcatt
    48661 gttttcagat gaaaatattt gattttcttt ttccacagat actgtgtaaa actacgcgga
    48721 taggattgga aaaataaggg ataaaacata tccacagcct gtgtataaag tggataaatt
    48781 cttataaaac gtatgtttgc ctaatgaatg tgatgaaata aggtaaaata acactgtttt
    48841 ctgtggataa acctgtggat gttgtgcata actgttgggg aaatcttttt aacaaaaata
    48901 gccaaaataa acatatagac gaaaaaattg attataataa acaaagtgag catgaagacc
    48961 aaaggagaga aaacatgaat atcaaaatta tctcagtagg aaaattaaaa gaaaaatacc
    49021 tgatccaagg tatcaatgag tatgtcaaac ggctgaatgc ctatgcaaaa atcgaattga
    49081 tcgaagttcc tgacgaaaaa gccccggaga atttaagcga agcgcaaatg agacaagtaa
    49141 aagaaaaaga aggggaacgg atcttagcga aaatcaaaga acaagaatac gtctatgcct
    49201 tagcaattga agggaaaaat cctacaagtg aatcttttgc taaacaaatc gaccaattag
    49261 gtatccaagg aaaaagccac cttgtttttg ttatcggcgg ctctttagga ctcagcgaag
    49321 ccgtcatgaa aagaagcaat gctcagatct cttttggaaa aatgacgtat ccacatcaat
    49381 tgatgcgtct gatccttgtc gagcaaatct accgtgcctt ccggatcaat gcgggggcgc
    49441 cttatcataa gtgatgcggt ttttatcatt gatcctaaaa atcttagcaa gacaaaaagt
    49501 acgtaagaaa gtaaagacta aatacttcgg aggaacaaat gaataacaat gataggttat
    49561 tgcgattgcg ttatgcgatt gatttgaaag atacggattt gattaaagct tttgagctag
    49621 gcggtgtacc actgactaaa gaagaagctc aggcggtact gaccaaagta caggataaga
    49681 acaaagataa tgcagaaaat aatgtgtatg aaaaaaccat caacaaccaa gtttttgacg
    49741 cattcctaaa tggcctgatt ctcttggcgc gtggtccgca aaaagataag ccgatagtag
    49801 acacgccgca aaaaagcaag gaaatcaaat atatcaacaa tgtgttgcta aaaaaattaa
    49861 aaatcgcctt gtctatgacc actgatgata ttttagacgt ttttgctgag gcagaaatct
    49921 atccatcaaa aggcgaaatc ggggcatttt tgagaaaaga aggccaacga aattttaagc
    49981 cttgcggaga taaatatatg cgtaattttc tcaaggggtt aggaatttat aatcggagaa
    50041 aagtataaag aaatttcatg agaaatcaaa acaatggttg ttttgatgag agctagtttt
    50101 tgtatgagat taaaatatta tcttaatcga ggagctggat tggttttatg aatgatgaat
    50161 ataagaatga tgaagataag atgctttttg aagagataga gaatcgatgt aggctcaatt
    50221 ttgagcttcg gggaaagatg tctttaatac aacaaaaaaa gtatttagcg aataaatcag
    50281 agtttactct gggacatgtt gaaaaattaa tctcggattg gattagtagt agaagcgaat
    50341 ttacaaaaat aaaacagccg attaaatttg acatgaaaaa acttttgtta aataagagtg
    50401 agataggtaa tagagatcaa tatattagag ctaaagggca agaaataatt gattcattag
    50461 gtgaaatgag gtcatacaat tatttgtatg taacacatag agctgatgga atggtcatta
    50521 ctgtggggaa atcttcttct aatgatattt ttttagatgg agatcttttt tatcaactca
    50581 atacaaatca cttgtctggc actgaaaata taattttaag gacggaatat ggcaatgaaa
    50641 tatttgcaaa atatgatgag attttaaaaa attatttgga ctgggcttgg ataattccgg
    50701 ttgagtcagg agatgctaag aaactggaga gattattggg cgatgaacta attaataaaa
    50761 aagtaccaat tttaaattat tattcccata gacaataaaa ggctattttt catgataata
    50821 ctagttataa ctgtaaaaat ggaagaaaat ctgggaaaga agtttttaaa taagtgtatt
    50881 gttcgatttt aataaataat aagcaatacc atccgtctgt gttgcgcaac atcgtactac
    50941 aatgaatatt ttttcacaaa aagaaaatca tccatcgaat gaatggaagg ttttagtata
    51001 cacgaggtta atgccccctc ttttataatc agaggagtga ggttttttct atgaatgttt
    51061 ctattttctt attgctagtc tagtttctct tacgatgaaa ttgggattct attccagttt
    51121 ttattgattt gctgataaaa taacttgaat ggtggatata aacatgataa ataagagaag
    51181 aataacaaaa caaggttgtg aaatgattct caaatgaata taatagaaag aaaaaggagg
    51241 aagaatcaat gaaaatagca attgcaggcg ctggcgcaat gggaagtcgc tttgggttaa
    51301 tgcttcacca aagtgggaac gaagtattat taatcgatgg ctgggcagaa catgtccaac
    51361 aaatcaaaga gcatggatta caagcaaatt ttaatggtaa agaggtagaa gcaaaactac
    51421 caatcgttct tcaatccgaa gtagaaaaag aagatcaagt tgatctgatt attctattta
    51481 ccaaagcgat gcagctggaa aaaatgctgc aggatatcca atcattaatc aaaaaagata
    51541 cagaggtctt atgtctatta aatggtatcg ggcatgaaga tattattgag aaatttgtac
    51601 caatggaaaa tatctatatt ggaaatacca tgtggacggc aggtcttgaa ggtcctggtc
    51661 aggtcaaatt atttggaagt ggttcagtag aattacaaaa tttaggtgat ggaaaagaag
    51721 cagctgcaaa aaaattagca gacaaattgt ctgaatcagg attaaatgct catttttctg
    51781 acaatattca ctattctatt tatcgcaaag catgtgtgaa cggaacaatg aacggactat
    51841 gcacaatctt agacgttaat atggctgagc taggaaaaac atcgactgct cataaaatgg
    51901 tggcgacgat tgtcaatgag tttgccaaag tagcagcagt agagaagatt gaactagatg
    51961 tcccagaagt cattgcacat tgtgaatctt gttttgaccc ggaaacaatt gggttacatt
    52021 atccttcaat gtatcaagac ttgattaaga accatcgatt aacagaaatc gattatatca
    52081 atggcgcaat ttctagaaaa gggaagaaat atggtgttgc gacgccttat tgtgatttct
    52141 tgactgagct tgtccatgca aaagaagata gtttgaacgt aaaataaagg agagattgaa
    52201 tggaaacttc acaaaaaata tcaccgaaaa tttttctgaa taaagtcctc gctggtacag
    52261 caacaggaat cattattgga ttgattccta atgcagtatt aggtgccatt ttaaaatatt
    52321 ttagtgcgta tccctttgcg gtaacgatcg cacagttagc agttattttt caactagcaa
    52381 cacctttgat cattggtggt ttgattgcct tacaatttgg atttgatccg atgagaatga
    52441 tggttgtagc cggagcttct tttgttggtt ctggtgtagt caaattcaca cctgatttgg
    52501 gtgaaacggg tgtttacgtt ggtgctggta caggcgatat tattaatacg atgctgacag
    52561 catcgattgc tgtcgggctg attttactga ttggaaatag ttttgggtca gtgtcgattg
    52621 tgttaacacc gattgttgta ggtgtaggtg caggtttact tggtttttat ttattccctt
    52681 ttgtaacagc aattacttct gcaattggat cattgattaa taacttcact accttacaac
    52741 cgctgttaat gtctatcttg attggttgtt cctttgcctt tttgattatc tctcctattt
    52801 caacagtagc aatcggaatg gcaatccaac tagatggtgt ttctgctggt gcggctgcga
    52861 tgggcgtagc tgcaaccact tttgttttag tagtgaactc ttggaaggtt aataagtcag
    52921 gtgtgacaat tgcgattgct ttaggcgcta tgaagatgat gatgcctaat ctatttagaa
    52981 aacctgtgat tcttattcct tgtttagtta gtgcagtgat tacagctatt cctgtcgctc
    53041 tattttctat ttcaggtacg cctgcttctg ctggtttcgg cgtggtcgga cttgttggtc
    53101 cgttggcttc tttagatgca gggctaaatg gctttcttgt tgttctttgt tggttagtca
    53161 tccctgtttt tgcggcacta attactcaat ttttatgcga gaaagtattt aaactgtatg
    53221 atcgagaaga agtcttcaaa tttttaggct agtagatttt a
//
LOCUS       DAIGSZ010000014        51458 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.014, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000014 DAIGSZ010000000
VERSION     DAIGSZ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.014"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            111..1253
                     /locus_tag="NOB31_000839"
     CDS             111..1253
                     /locus_tag="NOB31_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCI0973072.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEIIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYKNGGADCRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVQFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDIADVIESEGVFYE"
     gene            1246..1452
                     /locus_tag="NOB31_000840"
     CDS             1246..1452
                     /locus_tag="NOB31_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HCI0973073.1"
                     /translation="MSNAQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEQVIDKLDAI"
     gene            1531..2724
                     /locus_tag="NOB31_000841"
     CDS             1531..2724
                     /locus_tag="NOB31_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0973074.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKTSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNEQRANVKKST
                     MKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKEKGFSYNTINNHKRSLKASFY
                     IAIQDDCVRKNPFDFKLSEVLENDTKEKVALTEEQEQALLSFIKTDNVYHKYYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKNGTRQVPLSR
                     ETIQAFQRVMKKRPKAEPFVIDGRSNFLFVNHKGKPKVAIDYNALFVRMVKKYNKQHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(3269..3736)
                     /locus_tag="NOB31_000842"
     CDS             complement(3269..3736)
                     /locus_tag="NOB31_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HCI0973075.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(3856..5394)
                     /locus_tag="NOB31_000843"
     CDS             complement(3856..5394)
                     /locus_tag="NOB31_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HCI0973076.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            5474..6160
                     /locus_tag="NOB31_000844"
     CDS             5474..6160
                     /locus_tag="NOB31_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HCI0973077.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(6361..6888)
                     /gene="msrA"
                     /locus_tag="NOB31_000845"
     CDS             complement(6361..6888)
                     /gene="msrA"
                     /locus_tag="NOB31_000845"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI0973078.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(6972..7649)
                     /gene="pgmB"
                     /locus_tag="NOB31_000846"
     CDS             complement(6972..7649)
                     /gene="pgmB"
                     /locus_tag="NOB31_000846"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCI0973079.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(7646..8774)
                     /locus_tag="NOB31_000847"
                     /pseudo
     CDS             complement(7646..8774)
                     /locus_tag="NOB31_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(8774..10957)
                     /locus_tag="NOB31_000848"
     CDS             complement(8774..10957)
                     /locus_tag="NOB31_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCI0973080.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(10954..11979)
                     /locus_tag="NOB31_000849"
     CDS             complement(10954..11979)
                     /locus_tag="NOB31_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0973081.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(12024..12851)
                     /locus_tag="NOB31_000850"
     CDS             complement(12024..12851)
                     /locus_tag="NOB31_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCI0973082.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(12848..13915)
                     /locus_tag="NOB31_000851"
     CDS             complement(12848..13915)
                     /locus_tag="NOB31_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HCI0973083.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(13941..14777)
                     /locus_tag="NOB31_000852"
     CDS             complement(13941..14777)
                     /locus_tag="NOB31_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0973084.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(14774..15643)
                     /locus_tag="NOB31_000853"
     CDS             complement(14774..15643)
                     /locus_tag="NOB31_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0973085.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(15713..16996)
                     /locus_tag="NOB31_000854"
     CDS             complement(15713..16996)
                     /locus_tag="NOB31_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCI0973086.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(17010..18695)
                     /locus_tag="NOB31_000855"
     CDS             complement(17010..18695)
                     /locus_tag="NOB31_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HCI0973087.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            18970..19995
                     /locus_tag="NOB31_000856"
     CDS             18970..19995
                     /locus_tag="NOB31_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0973088.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(20590..24264)
                     /gene="rpoC"
                     /locus_tag="NOB31_000857"
     CDS             complement(20590..24264)
                     /gene="rpoC"
                     /locus_tag="NOB31_000857"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HCI0973089.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(24322..27939)
                     /gene="rpoB"
                     /locus_tag="NOB31_000858"
     CDS             complement(24322..27939)
                     /gene="rpoB"
                     /locus_tag="NOB31_000858"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCI0973090.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            28667..29635
                     /locus_tag="NOB31_000859"
     CDS             28667..29635
                     /locus_tag="NOB31_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0973091.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            29653..30558
                     /locus_tag="NOB31_000860"
     CDS             29653..30558
                     /locus_tag="NOB31_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973092.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            30555..31361
                     /locus_tag="NOB31_000861"
     CDS             30555..31361
                     /locus_tag="NOB31_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0973093.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            31497..32486
                     /locus_tag="NOB31_000862"
     CDS             31497..32486
                     /locus_tag="NOB31_000862"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HCI0973094.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(32803..33327)
                     /locus_tag="NOB31_000863"
     CDS             complement(32803..33327)
                     /locus_tag="NOB31_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HCI0973095.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            33614..35368
                     /gene="scm"
                     /locus_tag="NOB31_000864"
     CDS             33614..35368
                     /gene="scm"
                     /locus_tag="NOB31_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HCI0973096.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSS
                     TTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVI
                     LLVIGLRITFMSYKKSKR"
     gene            complement(35523..36509)
                     /locus_tag="NOB31_000865"
     CDS             complement(35523..36509)
                     /locus_tag="NOB31_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCI0973097.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(36532..37098)
                     /locus_tag="NOB31_000866"
     CDS             complement(36532..37098)
                     /locus_tag="NOB31_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HCI0973098.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(37112..37528)
                     /locus_tag="NOB31_000867"
     CDS             complement(37112..37528)
                     /locus_tag="NOB31_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HCI0973099.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(37985..39919)
                     /locus_tag="NOB31_000868"
     CDS             complement(37985..39919)
                     /locus_tag="NOB31_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0973100.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            40200..41156
                     /locus_tag="NOB31_000869"
     CDS             40200..41156
                     /locus_tag="NOB31_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HCI0973101.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            41246..42349
                     /locus_tag="NOB31_000870"
     CDS             41246..42349
                     /locus_tag="NOB31_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HCI0973102.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            42362..43315
                     /gene="menA"
                     /locus_tag="NOB31_000871"
     CDS             42362..43315
                     /gene="menA"
                     /locus_tag="NOB31_000871"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HCI0973103.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(44250..45596)
                     /gene="gor"
                     /locus_tag="NOB31_000872"
     CDS             complement(44250..45596)
                     /gene="gor"
                     /locus_tag="NOB31_000872"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HCI0973104.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(45730..46983)
                     /locus_tag="NOB31_000873"
     CDS             complement(45730..46983)
                     /locus_tag="NOB31_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCI0973105.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(46989..47912)
                     /locus_tag="NOB31_000874"
     CDS             complement(46989..47912)
                     /locus_tag="NOB31_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCI0973106.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFFKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(48133..50625)
                     /locus_tag="NOB31_000875"
     CDS             complement(48133..50625)
                     /locus_tag="NOB31_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HCI0973107.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(50632..51099)
                     /locus_tag="NOB31_000876"
     CDS             complement(50632..51099)
                     /locus_tag="NOB31_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HCI0973108.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(51235..51308)
                     /locus_tag="NOB31_000877"
     tRNA            complement(51235..51308)
                     /locus_tag="NOB31_000877"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(51272..51274),aa:Arg,seq:acg)
     gene            complement(51366..51439)
                     /locus_tag="NOB31_000878"
     tRNA            complement(51366..51439)
                     /locus_tag="NOB31_000878"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(51403..51405),aa:Pro,seq:tgg)
BASE COUNT        14907 a        10921 c         9603 g        16027 t
ORIGIN      
        1 ccccaaagct gtaaggagta atgaggagtt ttaagaagat agtaatttca cattcttttg
       61 aatagtggtt tacaggtatt tcaaggctat tgtgggattg gaggaataca atgaacaatt
      121 tagaatttgc acttgaaatg aagaataaac gtcttgcaag cggtctttca caaggagaac
      181 ttgcaagtct tacccatgta tcaagatata gtatcaaccg ctttgagaac ggaaaagcca
      241 acgccagcaa ggaaacacaa aatattatcc tgcgttgtct gaattactat atctgcgata
      301 agccttttta tctgctcgtt gattatctgt ctgtccgttt tccaacgact gacgcattgg
      361 aaattatccg aaaggtgctt ggcatgaaag cagattattt tatccattat gactatggat
      421 attatggcta taaagagcat tacgcctacg gagaaatcaa ggttatggct tctgatgatg
      481 aacacatggg cgtatttttg gaattaaaag gggcaggctc acgcaatatg gaatatgttt
      541 tacaggcaca gaacagggat tggtattcat tcttgaaccg ctgtcttgac tgtggcggtg
      601 ttatccgacg ttttgacttg gcaatcaacg atatgtgcgg tctgctggat attcccgttt
      661 tatctgaaaa atacaaaaat ggcggtgcgg attgtcgctg taaaaactat gaaaatgtgc
      721 aaggcggtaa actaagcgga aaaaaccgca atttagcaag caccctttat atcggctcaa
      781 aagcaagcac aaaatatttc tgcctgtatg aaaaacaaaa ggaacaggca actaaaaaga
      841 aacatacgga tattatcaac cgttttgaaa ttcgtctgcg tgacaaaaag gcagtacagg
      901 cagttgagga actgttattg acgtataacc ctcatgggct ggtgttttac cttattactg
      961 attttgtgca atttcccgac tatccgctgt gggagatatt catttcccat gatagtttac
     1021 cttttgaaat gaaccccgta cctgtcaata tggaacgcac tctgcaatgg ctggaaagac
     1081 aggtcatgcc gtcaatcgtg atgatagagg aaatcgacag gctgacaggc tcaaactaca
     1141 tgaaaatgat tgatgaatgt acccaccttt ctgaaaaaca ggaaatgctt gtggaacaaa
     1201 tgtgtacgga catagcagac gtaattgaaa gtgagggggt gttttatgag taatgcacag
     1261 gatattcccg tatgggaaaa atacaccctt accattgaag aagcgtcaaa gtatttccgt
     1321 atcggagaaa acaagttaag acgcttggca gaggaaaaca aggacgctgg ctggctcatt
     1381 atgaatggca accgcataca gattaaacga cgacagtttg aacaggttat tgataaattg
     1441 gacgcaatct aatgcaaatg agccttgtat gtgttatgat gaacacaagt catatcaagg
     1501 ctctttccaa caaggaaagg agcagacacc atgaaagaaa aaagacggga taacaaagga
     1561 cgtatcctgc atactggaga gagccaacga acagacggaa aatacttgta taaatatgta
     1621 gacgcatttg gaaatacaaa atatgtgtat gcttggagat tgacacccac agacccgaca
     1681 ccaaagggaa aacgggaaaa aacctcactt cgtgaactgg aacagcagat aagacgggat
     1741 attgaggacg gtatcgacag cacaggcaag aaaatgacgc tttgccaact ctacgccaaa
     1801 cagaacgaac agagggcaaa cgtgaagaaa agcacaatga aacaacggga acagctcatg
     1861 cggttattga aagaggacaa gttgggtgct aggagcattg atacgataaa accctctgac
     1921 gctaaggaat gggcgttacg catgaaagag aaaggctttt cctacaatac tattaacaac
     1981 cataaacgct cgttaaaagc gtcattctat atcgccatac aagacgattg tgtaaggaag
     2041 aacccttttg atttcaagtt aagtgaagtc ctagaaaatg ataccaaaga gaaagtggca
     2101 ttgacagagg aacaagaaca agccctactg tcatttatta agacggacaa cgtgtatcat
     2161 aagtattatg atgatgtgct gatactgtta aagactggac ttcgtatctc ggaactgtgc
     2221 ggactgacag tagccgatat tgatttcaag aatgaagttg tgattatcga ccaccagtta
     2281 ttaaagagca aggaacaggg ctattatatt gaaacgccta aaacaaagaa cggaacaagg
     2341 caagtgccat taagcagaga aacaatacag gcatttcaac gggttatgaa aaaacgccca
     2401 aaggcagaac catttgtgat agacggacgg agcaattttc tgtttgtcaa tcataaaggc
     2461 aagcccaaag ttgcgattga ttacaatgcc ttatttgtcc gtatggtaaa gaaatacaac
     2521 aagcaacaca aggacaatcc cttgccacat atcacaccgc atacgctacg ccatacgttc
     2581 tgcacaaggc tggcaagcaa gaacatgaac ccgaaagatt tacagtatat catgggacat
     2641 tcaaacatca gtatcacaat gaactggtat gctcatgcgt ccatagatac cgcaaaatca
     2701 gaggttcagc gtctaatcgc atagaagtat ttaccacgat tttaaccacg tttgatagcg
     2761 aaaatataaa aagatagacc tagatatgtg aggtttacca caaaagcaaa atgcccgtag
     2821 agccgataaa ataaggcttt gcggacattt gagaagatat aaaaagatag tcaaaaaggc
     2881 atatataatt tatatgaaac tttacttctt ttctttcttt tatataaaag ggtcgtttcc
     2941 tgtcaaaatg aaaaacaaaa agaggctgtg acaaaagtct tgtcacaacc ccttattttg
     3001 aataaacggt gttctcctgc caactcctcg gtcacaagtc acaatatcca taaaacataa
     3061 gaagctgttt tttaaaattg tttcttgtga ctcggagctg aacggcaggc ttacaacctc
     3121 ttggtaaacg gtgttcaatc agctgaccct cggtattagc tcaaaaaacg gcaaaatatg
     3181 aggaactatt ttgacgtttg tttctctaat actcaggtca aaacgctgat ttcacaacct
     3241 ctttttcggt caagttcaac aacagttttt acgcgtcgat ctctggcgct ttgcccaaat
     3301 gagcttggat catccagata cgtttttctg tggctgtttt gaattcgata aagatatctt
     3361 gtgttggatc gtcgccttct tctccagaaa cttcgattcc tttttggtaa agatctgcta
     3421 gataacgata gcctgcaaca agtgtttcca aacgttctgg aatagtacga tcccagcggc
     3481 caatttcatc agggattttt gtgttatctg caaattcacg caatgtagaa taaggtgaac
     3541 cgtctaatgt gatcaagcgt tcggatactt catctaactg agcgttcaaa tcatccatga
     3601 actcatccat cattgggtgc aatgtaagga aacctggtcc tctcatgtac caatgtgttt
     3661 ggtgaacaac aacagacatt tggcttagat ctgcaactaa ttgatttaat acttctttgg
     3721 tttgttggaa tttcatcttt cttgcctcct aacattttct tacacttaaa ataatagtag
     3781 actttcaatg aaaagtacaa caaaatcatt tacctgagaa cgattttcag ttcgcttttt
     3841 tatccgtaaa gccaatcatt tttcagaatc agctaattct tctcgcagtt gagcaaattg
     3901 ctgataagtc tgtgctaaat gcttttgtgt cgaaacaaat aatggataga ttttctgata
     3961 ttttttatga tcagtttctt gtactccaac ttgctctttc aattctatca attcctgtgc
     4021 ttcactgata ctttggatct ttccgatgct tctccagcct aaaatcacag ctcctaatgc
     4081 ggatgcttct gtgacagtag ggaaaacaag cgggtaaccc agtacatcag ccatcatctg
     4141 acgaaaaatc ggagattgag caaacccgcc tgtagcacgg atctctgtga gctgattttc
     4201 ctggcaaact ccttttaaaa tccgataaag gttgagacag atcccttcta gaatcgcctt
     4261 catcatttct ttttctgtat gttgccgctg taaaccgata aaactgccaa acgcatctgc
     4321 gtcccaaagc ggtgctcgct caccaagtaa atagggatga aaaatcagac cattggcacc
     4381 cgctggcaca aaagcgatag ccgaaagcag tgcatcatat ggattttctc ctttttcttt
     4441 agcagattga acgacttcct gtaaaaatgt atgccctgcc caatcaaaga tgccagcacc
     4501 attgctagtc gctcctccca ctacccaatg tttctgatcc agaacataac aaaacgtctc
     4561 catttctgga tggaactgag gctgagtagt aataaaacga agtgctccgc tcgttcctac
     4621 ggtcaaagcg gcgatcgtat caccaaaagc acctaaccct agattagaaa gcggcccgtc
     4681 tgcccctccc aaaacaaatg atatatcatt tggcaaacct agttctgctg ctgtttttga
     4741 tggtagacct gttacttgat aggtggaagg aaagacttgc ggcaattgct ctattcgaat
     4801 gttcaagtag tcaagcactt cttctgccca ttggaattca tggatatcaa aatatccagt
     4861 tcctgaagct gttccgtagt cgctgatcag ttcgccaaac aatctataaa agatatagtc
     4921 tttgataccg acaaaataag cagttttttt gaataattca ggttggctgt tttgcagcca
     4981 cttgattttg ttcaatggtg tcattggatg aatcggcgtc ccagtctgcc gataaaattc
     5041 tttgccaagc acggtatatt tcagtttttc tgcttcgtcc gctgctcggt tatctgccca
     5101 agtgatcatt cgagataacg gtgttttctc ttcatccaac aatatcaggc catgcatcgc
     5161 agaggagaag gagacaaatt gaatgattgt gtctgaaggc aactgtttaa ttacttcttt
     5221 tataacggtg cagacacctt gaaagatcaa ttcctgatct tgttctgcca tcccttgtgt
     5281 ttcttggatc aaagggtagc gaaaataagc ggatgctgct tcttgggctt catctgtgaa
     5341 agcaactgct ttggtttgtg tggttccgat atctaatccg attgaaacgt tcattttttc
     5401 acctcaaatt ttatgtatgt acaaaaattt agtttaagct tgcgtatctt ggttttgaaa
     5461 agggggagat ggcgtgttac tttattttat cattggttgc tgtatcggat catttttatg
     5521 tttaaccgcc cagcggattc cgttaggtca ctctattatt tatcctagat ctcattgtgt
     5581 caaatgctgt cgttcgcttt cttggtatga attgattccg attctctcga tcatcgtcca
     5641 acgatttcgc tgccgctatt gcaggtgtcg gttgcccttc tactatttgt tggcagaagc
     5701 cttatgtggt ggtctttttg cctggttctt tactttttct tccgcaagaa atttttcgac
     5761 gttcatatgg atgctttcgg ctttgctatt ttcgttgatg gatttatttt acttcatggt
     5821 ccattctcac acgctattct gttcttgggc aattttatgg attttttggt tgcaggccgg
     5881 cgtcttccaa tggcaaagtg tgctgttaac gtttatcgta ggcggtgtgt gccttcgcta
     5941 tggtcaatcc tatctcggag ctggcgatac tctgttgatg ctttcttgga gtggtggctt
     6001 gtctctagaa gagttgcttc agatcttgtt tcttgctagt ctgtttggaa tatccgtttt
     6061 ttctgtttac tttatctgtc ataaaaaaaa gttggaaaag ctgcctttca ttcctttttt
     6121 gagcagtgcg ttgctgattg tccttcatct taggtattga aaaaaggttg tgacaaacga
     6181 cttgtcacaa cctctgatat atagtgttct cttaccaaat ccttgtgact tggagctagg
     6241 cgacaggttc acaacctctc cactaaatgg tgttcaatca gctgaccctc agtattagct
     6301 caaaatgctg gttttacaac ctctgatata cggtgttcca taagtagctt tttcggcttc
     6361 ttatttcttg acgccccaat gtcgacgaag gaaacctgca cgtccagaac cttctcgata
     6421 aagattgtaa tggagcttgt ttttcttgta ataatcctga tggtaatctt ctgcaggata
     6481 aaattcgctt cttggttcga tttttgtcac gattggctta tcgaatcgcc cgctgtcttg
     6541 caatgcttgt tttgaacgct ctgcaatatt tcgttcttct tcatcattat agtagatcac
     6601 tggacgataa gaatcaccgc gatcagcgaa ctgtcctaat gcgtcagtcg gatcggtttg
     6661 ctgccaatag atttccacca actgatcata agaaataact tctggatcat attcgatctc
     6721 tactgcttct gtatgccctg ttgtgcctgt tgttacttgt tcataagttg gatttggtac
     6781 atgcccgcca gtataaccgg atgtcacaga aatgatccct ggctgctctt caaatggttt
     6841 gaccatacac caaaagcatc cgcctgcgaa aactgctttt tttgtcatat aaaatccccc
     6901 ttttttctca tcataccttg atttccaaaa ggaggataac gttttgcttg tgacagaaaa
     6961 aacggaaact attatatacg tgatacggct tctgataaat gccaaaacga acgtacttga
     7021 tcaaaaacgg ttaaatcagg aatcacatat tcagcagaag gaagatttat gttttcacct
     7081 attcccaata catgcatgtt accagccaaa gctgcttgac aaccagcttc tgaatcttca
     7141 atgaccaagc atgcatttgg cggtacattc aattgctgtg ctcctttgag aaaaacttct
     7201 ggatcaggtt ttgcttttga tacttgcgtg ccgtcaataa ggacatcaaa ataacttgtc
     7261 aaattcgttt tttctaaaat gaggcgtgca tttttgcttg ctgatcccaa tccgatcttg
     7321 atgtttgttt ttttcaagta ctcaagaaca gctattgcac caggcaaaac ggatgtttca
     7381 tccatttttt gaatcgcttg aagatataga ttgttttttt gctcagcaaa ggctgatttc
     7441 tctttttctg agaatttctg ttccattttt ccaaatgaca gcaatcgctc tagtgactcg
     7501 gttctggata ttcctttcag ttgctcgttt tctttctcag tgaatggaat ggacagctgg
     7561 ttagctaaaa ccagccacgc ttcgtaatga taacgagctg tgtctacaag aacgccatct
     7621 aaatcgaata gtgctgcttt gattttcatc gattacctcc ttgaaaatga acgacttgaa
     7681 gtaaagatgc gatgttttta gctgtgcgat gaagattatc agtggcttgc tgtaaagctt
     7741 cttgtaaagg cacagctgca ggaaggatcg gaaaaacggc cgaaatgcca acatctgctg
     7801 ctttttcgct tcctttacca acacttccgc aaatagctat cacaggaacg ccctctggta
     7861 ctcttctagc aatcccaact ggcgcttttc cttttagact ttgtccatct agacgtcctt
     7921 cgcctacgat tacgaggtct gcttgctgta cccgtatcga actccagtaa atccaatacg
     7981 tagtcgatgc cagagactat tttccctgaa gcaaatgcta acagtcctgc acccattcca
     8041 ccaccagcac tactgcccga tgcctcgatt acttgagggg caaatctcat ataaaaatca
     8101 tgcatggctt ggtcagccac tgctaattca ttttctttca agcctttttg tggtccgaaa
     8161 acaaaagaag cgccttcttt tccgcataaa agattagtaa catcagtaat gacagtgatt
     8221 ttggctttaa tcagctcaat aggcacgttc gttttatcaa ctgtagcaat tttacctaga
     8281 ttttctccca gtgcttctac tttttgatta tcttgatcgt aaaaagcata acctagacct
     8341 tctgccatgc cgatgccgcc atcgttggta ctacttccgc caacgccgat gatgatgtgt
     8401 cgaacacctt gttgcaacaa ttgtcgtatc agttctccta ctcctcgcgt ggataaccta
     8461 agtggctgtt gttggtttag tgggacatct ttcaatccga cgatttctgc catttcaaaa
     8521 atcgcagttt gaccgtctga agcgtactgg atttctttgt ttttgccaaa tgcattagta
     8581 acgactgctg tttgccgctt caaccttaaa ctgtctgcta atgatgaaac cgttccttct
     8641 cctccatcgc ctataggtag cagatcatat tcagcctgaa caaaaacttc ttgaaaacct
     8701 gattgaatgg cttgtgctgc ctctaaggct gtcagacttt ctttgaaaga atctggcgca
     8761 atcagaatac gcattatttt cccctccgtt ccaagatcag ttctttttcc agctggtatt
     8821 ggtctccatt gacaaaaata ggtaatgttt ctttcgtctc tttttttatt actatttgtt
     8881 tttttgtcaa aacaaatagc aacctgtgat ttttccaaat aaaaggaaaa gaaatttttt
     8941 cccatgctga aggaagtctt ggagaaatag aaagagttcc attcgttact gtaatacctg
     9001 aaaaaccaaa tataactgct agccatagtg ctcctaatga agcagcatga attccgtcat
     9061 ctgatgaatg cggatctggt cctaaatcaa tcaggcacgc ttcttggaat aaatgatacg
     9121 cccattccat ttcttggata cggcaagcct ctatggcgtg aatcgcttta ctcaacgatg
     9181 agtcgtggat tgttttgttt tcatagtaat gcaaattctt agaaacgatt ggttgagaaa
     9241 aatactcagg taataagtat aacagcatga caagatctgc ttgcttgctg acttggagtt
     9301 catttacttc gctacgggca taatcaagta aaatagactg gctgccagga cgttctttgt
     9361 aagtggtcaa atcaataact ggcttactga gatacgtgtc atcttgcgga atcagctgtt
     9421 ctttgttagg cactggcaaa tataacttat ctaaaaaatt ttgacattct ttcaaaaaaa
     9481 gcggatcgcc agcttgatat ttaacagcta aggccacatt ataatgcgcc agatagttcg
     9541 tatatgcatt attgtcgata tattctgtgt attcatctgg accaatgact ctgtgtatct
     9601 ctaaatgatc atcgactttt acagctctgc tcagccaaaa agctgctgtt tcatgaatga
     9661 gcgtttttcc ctttgtttct aaaaacgatt gatcctctgt tgcttggaca tactcttgaa
     9721 cggcataagc aaggtctgca ctgatatgat gttctgcggc agctgaagca acttcttgtc
     9781 ttgttccggt tttgatattc aatgcagcaa atttgggtgt ctcttcctga ccagtgtgtg
     9841 cgctttccca tgggaaaagt gcaccttgat agtgataatc tcttgctttt tgccgtgcgc
     9901 cttctaatcg atcataacgg tacagcagca aattctttgc tacttcagga aactgatata
     9961 aaaagaaagg caggataaaa atttccgtat cccagaaaac atgcccttta taaccttcgc
    10021 cagttagtcc cttcgcccct acactaacac ttggatcatt gcggggagtc ataatctgta
    10081 aatggtaagc agcgaagtcc atcgctaact gatcgaaaga agaatcgcct tggatcgtta
    10141 tccgatgctg atgccaaaaa tctgtccaat aagacatcga ctgctctaaa atttctgtat
    10201 aactaacgct tttctgggct tgggcaatac ttttcttaaa cgggtctgtt tgctgaagag
    10261 aggtagagag cacgatgatc ttctccagcg taaaggacgt attttttctg atcttttctg
    10321 aaaaggaagc ggtgatccgg cgattttttg cttggaatac acctgcttta ttgaatttag
    10381 ctgcaatccc aatatcaatt ttactttctg ttgtctggta ggatgcactg atcaaatcgt
    10441 caccaaatac tcgcagttct ttttcaacca actgctgtgt accaaaattg gtttgctgtc
    10501 catcgatacc cgttttcaca tctacttggc agtcttcggt caacggcttg atgaccactt
    10561 tcagggctgc ctgatggaga ttattttgat cagcaacacg acaagtaatg acttccactt
    10621 tttttccttg agcagtttca atgagcgcat agcgtttaag ctctcccatt tctaaatcta
    10681 gtgcccgctc gtatgcaaga actttcatcg tctcaagaga aaaatgttca ccgtcgattt
    10741 ttatttccca tctgatgaca tctgggagat tcactaactc ggctgattct gctcctaaag
    10801 gtcggttata tacaccagct gcaaacattc cccttacttg attccgatag tcttcctcct
    10861 ggcttcctct gataccaaaa aatccatttc caatggtcat ctgactcgca tacttattga
    10921 tatactctaa atcaaactgt ttttcttcta ctttcataag gtaataactt ctcctgtttc
    10981 tgccgaacga tataaatttt ccaccagatt ctggatgaca tatccttgcc agccatctgc
    11041 aatcatctga gtctggtcac cgagcgcccg attcacaaaa tgagccatac ttagttcatg
    11101 tgggtcatta actggcgtgg tcttttgtaa ggaaaccagc tttccatcta catcttcgaa
    11161 tagttcgcct ggatacagat tagcacctgc ctgatcgcca caaaaagcca cattcagttt
    11221 gtcttctctg atattcaaag caaacgaagt attcagttgg atgatcttgc cgttttctaa
    11281 ttccagtgtg ccaaaaattg catcttctac tgtgaatttg cttggatccc atttcccgaa
    11341 tttccctgaa ttttttttcg taccaatttt ttggaagctg tacgcccgaa cgctttttac
    11401 tttaggaaat ccagtaatat acatcgctgt atcaagcatg tgaatgccat aatcgatcaa
    11461 aggcccgcct ccttgaagtt ctttgtcgat aaacgttccc cagcctggaa caccagaccg
    11521 acgaagcgca ttcgcttcta cgtaataaat atccccgaga acatcaagat gattcttgat
    11581 cattgttgct tcgtcagaaa aacgatgctg gaatccataa gccaaaatct gcccgttttt
    11641 atcggctgtc tctgccatct ttcttgcttg atcagctgtc atagctggtg gtttctcgca
    11701 catcactgaa gcattagctt cgagggcagc caatacatgt tcgaagtgaa agcgattggc
    11761 tgtacagaca ctcacgatat cgggagaaat ctcattcagc atttgtgtaa ctgatgtata
    11821 cgcatgagaa aatcctgtac gtcggcaaaa gtcttctgct cgctggctga ctggatcaac
    11881 cacagcggcc aattctaaga catctgatct tttttgataa taagcagcat gtactttttc
    11941 tgctacttgt ccagcgccta tgattgctac tttcttcatt tatttctctc tcctttgctt
    12001 atttacttat tgttattctt tctctattct ttctctaaat catttaaatg acgcgctgtt
    12061 tccagacagt ttttcaagta ttgcaatgat tcctgataaa ttttcacttc attttctcct
    12121 cgcaaacgac attcatatac catataacct tcatactcat tttgaagtag cgtttgaaaa
    12181 tggcgagtaa aatcaattgc gccagatcct ggttggtagc gatgattatc tgctaaatgg
    12241 atatgaccca catactcttt ttgcgtagtc aatgcttttg aaatatcatc ttcttcaata
    12301 ttcatatgat aaaaatcagc gatgatctgc acatgtttca attgattaga gtcaatgtaa
    12361 tgacgcgcat ccgctaacaa attgatcata tggtcttggt atcggttcaa aggctccaaa
    12421 taaataaccg tacctgtttc ttcggctact ttatctaaat aacgaagtga ttcgctgact
    12481 gctttatagt ctccttcttt gcttcggggt gaaaccatcg gcggtaatcg ataagtgaac
    12541 attccccaag ctgctgggat aacgattcct ttgcctccaa cctcgcttag tgcacgcaaa
    12601 atctcagcaa tttgacgtac accattaaga cgccgttctt cgataaagtc accgatccac
    12661 ccatcgtagc cgttacaagc tgtcactact gggatccctg tttctttgat tgcctgtttg
    12721 actgtgtcga tattttctat taacaactta ccgtcgattt cgtattcttc aaatccacag
    12781 tctttgataa atctaaattt ttctaaaatg tctcttggga aaaatgcttg atcttgcgta
    12841 ccgaatttca ttgttctcct cctcggactt gaacgcccat tttgatactt tcttctgggt
    12901 gctggtctac ataacgcatg taagcttctg cgctttctgc aaatggcaca actggatcaa
    12961 tgatttcttc acaatccaag taaccgttca tcaataattc ccaacatgtg tcctcgattc
    13021 gtttacggtt ccatcttggg taatctgggt ttggttcact agatgctcga gcaaagacga
    13081 tttttgcatt attgaaatgt gcttcgcgac caagattaaa cccagctgga aaaggtttag
    13141 caaaggcaac ataagaaatg atcccgccat agccgatccc tcttaaagaa gcttgtaatg
    13201 cggcagcact gccactcgtt tcaataactg aatctactcc acgtttatct gtcaattcct
    13261 ttagacgaaa accgacatct gctttcatag gatctagcgt gtaatcggca ccgtattttt
    13321 ctgctaattc tctacgctgc gctatgggat cgatcccaac gatggtagta gcacctgctt
    13381 ttttagctaa ttgaatcgca atttgcccga tagcgcctaa accgaagatt gctacagcat
    13441 cacctgctcg aacatgtgct tcccggatac cacctaaagc gaattgagca ggatcgtaac
    13501 atactgcatt tttccattga tccaaccgat caagtttacg tagtttataa ttatcaacac
    13561 cgtttgtaat cagcgtttca cgaatgggtc cataagtgca gactaactct cctttttgat
    13621 actctgtcac caaactgccc gtttcttcga tcgtaccgac aatcatattt cctaattgaa
    13681 attcgccaaa taccacaccg cgttggcttc cttcttctct tggcaagaat aggcgccatt
    13741 cttctgaaaa ttcttcatcg ataaatggac ttaatcctct aaagtcgaca atttctgttc
    13801 ctggttttgg agtagcgaaa attactcgga tacgtacttc gttcttttcg atctcacggt
    13861 cttcgtaatc tttgaatccg gctattcttg gttctaatgc aactaatttt ttcatctttt
    13921 ctttcctctt tcttttcttt ttatcctttt acgccgcctt cgactaaatc acctttaata
    13981 aatcgttcag ataacgcata cataatgatg actggtaaag cggtcaccaa tgaagcggcc
    14041 atcattcgtc cccaaatgta gtctggtgta ctgaataatg tgttcaaacc gattggtaaa
    14101 gtaaattttt cggaggtcga caggaaaatc gaagcaaata aataatcatt ccacgaaacc
    14161 ataaagcaat aaacgaagac agaaatgatt ccagaaatag ccaatggtat aatgatccga
    14221 ataatgatct ggatccggct aagaccatcg atcattgctg cttcttcaat atcagtcgga
    14281 atcgtgtcaa aataactttt tagcatgaat atcgcagtag gaagtgtttg aacgaccatc
    14341 gtgataatca gtgctgtatt ggtatcatac aaacctagac cggaaatgat tttaaataat
    14401 ggaacaacga tcaaaatacc ggaaaacata taaacggtgt aaaagctagc attgattttc
    14461 gagcgagctt tgaagcgtag ttttgacaaa gcgtatgccc cgctgatccc aatcactact
    14521 gcagttacgg aggctatcaa ggagatcact aaactatttt tgaaatacat gatgaatgga
    14581 aaaatctcag cattgaaaat atcctgataa tgttcaaaag tccattcttt cggaaaaata
    14641 gtttgtgtcg ttgcaattgc ttcttgtgaa tccttgaatg atgtcatcag catgatcaaa
    14701 aatggaaaca aattgacagc taatagcaac aaaatcgtcg cgtaaaataa gattttcctg
    14761 ctctttttat ttttcatttc aagtccacct tctttcgtga gagcaagacg accgctgcaa
    14821 taatgatgaa caatagaatc gatatagctg ctgcttttcc aagatcattg aacgcaaagg
    14881 ctgtctgata caaataaacg cctaagatat tgactttatt cgtcagtaga tagacatctg
    14941 taaacatata gaacatccag atagatcgta aaacaatcac agttgctagt actggtttga
    15001 ttgccggcag tgtcacgatc ttgaacttct gccaagcatt tgcaccgtcc atttcagctg
    15061 cttcataaag cgttttgtcg actgtttgca aaatagccaa aaatgaaata aacgcatacg
    15121 gatagtatct ccagatagca aacaaaacga ccataaagaa gctagcaact ggctggtcga
    15181 accacagcgg tgcttcgttg aaaagctgca acctatctac taacagatca ttgacgattc
    15241 cataactatt attgaacata tatttccaag caaaaatcaa agaaatagat ggcgtaacat
    15301 aacttaataa aatcagtgaa cgcaccgttt tcctaaatct gaacttgcgg ttaagcaaaa
    15361 tagctacggc taatcctaaa gctgtactgc ctgctacaac taagaatgtg taagcaactg
    15421 ttaaacctaa agaacgataa aattcactat cacttaaaat ttcaagataa ttgcttaatc
    15481 cgataaaaac ggcgtctgag ttaggattca gcggcatatc gaaaaaactg atctgaatat
    15541 tggaaagcat tggaatcagc actaaaacag ctaataaaag catgcttggt gctaaaagtc
    15601 ccatggctaa ttttaagtca gaatgtttcc ttggacgatt cattgaaacc tccccctgat
    15661 aatctgccaa tagctatcta cttttttcga acaccattgg cagaacttct tgttatttcg
    15721 tatttttttg tgcgtcagct aaagcttgat cgacatcttc gtttccgaca gttacttggt
    15781 tcactgcttt tccgatcaca cctgagcttg tgatatctcc cattttcgtg aaattctttt
    15841 ccccgactag tccaaagact tgtacttcat caaaagcact agcaatctca gatggcagct
    15901 cgccaaaaga cttgatgact tcattttctt tgtaaccatc cagttcgact acttgtttat
    15961 tcactggttg agcaccacca ggagacatca agacccactt ttccatgttt ttcggttgag
    16021 ataagaaagc tgtgaatgct tcagcagcct ctttttgttt ctcgtctaga ccagaagaaa
    16081 tcgtcaatcc agatactgtg ccatagacag cttgatcttt ttgtgttggg atagcaaaac
    16141 cgatattttc tgagttcccc gcttcataaa cagaaggcaa aatgtaagtt gaatagattg
    16201 ccattggtgc tgttccattc atgaaagcat ctttgatttc tgtcacatca ttagagcctg
    16261 gcatcgtgta ttgggataag ttttgataaa acgacaatgc ttctctcatc ttttccgtat
    16321 cgatcgttac ctcgccttca tcatccaaaa catttgctcc atttgacaaa gcaaattgag
    16381 agaacgcttg ctcactcatt gttccttcag cagtaggcat agcaattcca tattgtttat
    16441 tctctttatc tgtgaaatgt tgagcaattt ttaaaatatc atcccaattt tctggttctg
    16501 aaaaaccagc ttctgataat ttttctttgt cataccaaat accttgaacc cagccgctaa
    16561 ttggtgcagc aatatagctt tttccatctt ctgaacgaac aaggtttttg gctccgtcat
    16621 aataattatc ttctccagct tcctcgataa cgttttggac tgccgtctga tcaatcagtt
    16681 catctttatc catcacttta gcaaaatcct gactgacttc cattacttct ggtaatttac
    16741 cggaacgagc taacgtaacg atttttgtat tgaacgctga ttcttctacc ggcacttgct
    16801 tgattttgat gtctggattt tctttttcaa aatcagcaac cagttcattg atcacactta
    16861 atcgttcctg ttcgacagaa gagtgcatga attgaatcgt tgtctgttgt gattcgttag
    16921 agctttgact ttcaccacaa gcagtaagaa gaaatccagt agctagcaga caggtagtaa
    16981 caataatttt tttcattttt ttccacctct tattttatta ttttcagcca catatattca
    17041 tacggctgga atatcaactt tcgttcttga ctgcaatgga taatttgtcc agaaaacagg
    17101 tctaggtaat ctccttttgg taaaagataa cctgctgatt gattggaaaa attatggata
    17161 actaagactt tctcttcctt cgcttcgcga ataaaactga taaaagaatc tgctgagtcc
    17221 agtaagtaaa tcaaactatt cggatggaag gctttttctt tttttcgaat agatagcatc
    17281 tgggtcaatt caccatatac tgctgttctt aatggatctg tctgcaactc tttctcaata
    17341 tctgctaaca aaaatttttg ccgattgatt tttcgattct ctcctgtttt ttctacgcct
    17401 ttgtaatcat ttcgacttcc cagcacactt tgaatataaa ttgccggcac gcctggtaac
    17461 gttaccaaaa atgaatgagc agctaaaaag cgtttgcttc tccattccgt cgtatctgtt
    17521 ggagaactta acgcatctag atacgtagcg tttatctcat atggactggt cgttccatct
    17581 gggtttttct tgtagtttac tcgggcaccc tctttcttca gctgttccac taattcaagg
    17641 atcgtttttt ccggcagaat acctcgtacc ggattcaatc cgataccgtc atgggaggct
    17701 aaaaaattaa aaaaagttgt ttttttcgat gcgaaatcga tggtttttaa ccattctttc
    17761 aacttacttg tattacccga acgaatcgct tgaagggtca aaggtggtag cgaaaactga
    17821 tagaccatct gtgcttcatt ctcgccattc ccaaaataac tgatattatc tttgtgtggc
    17881 acatttgtct cagtgatcaa taccgttcct ggagctgctt catcagcgat tgcacggaat
    17941 aattggatga ttttatgcgt ttctggcagg tgtatacaag aagttcctag ttctttccat
    18001 aaaaatccca cagcgtccaa gcgaataaat gaagcgcctt tttctaagta aaacaaaaga
    18061 atatcgatca ttttcaataa aacttctgga tttttaaaat tcaagtctac ttgatcttcg
    18121 ctaaaagtcg tccatacgtg tttttctttc ccgtttttgt caatgaacgt tgtaagtaac
    18181 gggctggtcc ttggtctagt cacgctgctt gtatctgtat ccagtggcaa atcaataaaa
    18241 aaatctttgt acgtatcatt caagtttaaa tattcctgaa accaagtact ttcggcagac
    18301 atatgattgc agacaaagtc gaacattaac cgtgtttcgc ttctcatttc ttctatatct
    18361 tcccatgtgc ccaaacggtc gttgattgcc tgataattta caacggagaa accatcatca
    18421 gatgtatatg ggaaaaatgg caagaaatgt acaactctaa atgtatctgc caaatacttt
    18481 tgataaaatt tcttaaatgt acgcaaagtt ggttgctgct cttcaaaaaa ttgatcccca
    18541 taagtaatca agaaaatatc ttcttcgtcc caatgcagtt tgcctgcctg gcctttcttc
    18601 tgctgataaa cactgacttt ttgttcaatc atagaggcgg ttttctcaga caaatctgag
    18661 tcgcgataaa tcgcttgtaa aagttttgta tacatcggat tcccctttct tttttgggag
    18721 cgttcccaac gatttgatca tattatggaa aacgcttact gtcaatagca tttttttaaa
    18781 taattttgat atacacaaaa atacaaataa gaaagcttat gtatcaataa ttaatagctt
    18841 cttaaaaaaa tatggtctct catgatcatg caagctattc ctaaattttc aaaatcatag
    18901 acaaaaaaga atgtctattg tactatggaa ttattctaaa acgctcccaa aaaggaggtg
    18961 catataaaat tgaaacctac tatttatgac attgcgaaaa aagctaatgt ctcaaaatca
    19021 actgtctcca gagtattaaa taaccagcca aatatctctg ataaagcaaa agcaagtgta
    19081 cttcaagcaa tcaaagaatt gaattatgaa ccgagcaaaa ttgcaagagg actgtcagga
    19141 aatggttttg acgcgattct agcattatct catcgtactt ctcatacgac ctatggcaat
    19201 cctttttttt cagatgttat tcaatccatt tctgccgttt ctgaacaaaa taacttcgac
    19261 ttgattctac aaacggcaaa aacaccagaa gaagagctag aaaaatgcgc gaaaaagatc
    19321 caagaaaaaa tgatccgagg aattattatt ttaagctcta cgatggatga aacacttctt
    19381 tttgaattgg atcaatacaa tattcctatt gtggtaatcg gaaaagtcgg aaacgactac
    19441 acgaacatct actcagtgga cacggataat ttccaggata gttacgattt ggtggaaaca
    19501 ctgatcaaga atggacaccg tcatatcggc tgtctccatg ctccgacaga agtttatgta
    19561 tccaatgatc gtctcaatgg ttaccgtcaa tgcttatttg atcaccacct agatatccgt
    19621 aatgaatgga ttatagacgg cggctttcgc ttagaagata gcatggcagc aatgaatgat
    19681 ttaatgaagc tacgagaaag accaactgcg attttttcta ccgatgcatt aaaatcattg
    19741 agtatttaca aagtggcaga acaatctgga aagcagatac ctgatgatct ttcgatcgca
    19801 ggattcagtg atcccttatt gtcctcccta ttttcgccac agttgactcg gatagacatt
    19861 ccgacaaatc agttaggaat caaagccaca gaacttttat tccaactaat ccaccaccaa
    19921 taccctgaag aaaaaagaat cattctttca accgagatta ctctcacaga ttcgatccaa
    19981 caacaagaaa tgtagaacag aattataaaa gaacagaaac actgaggata agtcagttac
    20041 tctgttcttt tttcaatcac tcatccctcg ttaccccctc ccggtatttt agcgaatttt
    20101 tcttattttc catctgtttt agatagctgt ggataactat aatgtttgtg ttaaactatt
    20161 ttttccacag ggaagaaaaa actattttta accacgttgt gtataagttt ttatagttcg
    20221 tttttttaaa cacatttacc cttatttcaa tccatgttat ttggggatac ttatctctaa
    20281 aacataaata gaataacaga catgtctact ggttttgttt tattcgagga attattcaat
    20341 aatagctagc aaaatattaa aaataaccgc tctatcttcc catcaattta ttttgcattc
    20401 aaaaaatgat ctatctttac ttttgttgat tgacttctct tggaagatga tcgttccgat
    20461 accttaattg gatacgaacc gatgttgtta agatcctttc ccacttttct tctagttaga
    20521 caaattattt tagacaaacc aaaaaagagg ttgtgacaat aatttgtcac aacctctttt
    20581 ttaaaatatc tattttgttt gattgttcat tgcgtcttct gcagccattt gcgcttcaat
    20641 atctgaaata ctgtagacat tttcgcttgc tacaccgact tcttttggtt ccatgtcacg
    20701 ataacgttgc ataccagtac cagctgggat gatcttacct ataataacat tttctttcaa
    20761 accaagaaga ggatctttct taccgcggat cgcagcatcc gtcaagacac gagttgtttc
    20821 ttggaatgat gcagcagata agaaactatt tgtttctaat gatgcttttg tgatacctag
    20881 taagacaggt cgagaagttg caggaacgcc tcctgagact agcgtattgt agttttgatc
    20941 tttaaagtct gcgatgtcta ataatgtacc tggtaagata tctgtatcac ctggatccat
    21001 tacacgaact ttacgcagca tttgacgaac cattacttcg atatgcttgt cgccgatttc
    21061 taccccttgc atacggtaaa cacgttgtac ttcacgaagc aagtagtttt caacagataa
    21121 tacatcgcga acttgcaaca attgttttgg atcgattgat ccttctgtca atggtgcacc
    21181 acggtggatc atatcgcctt ctgctacttt catacgtgct gtataaggaa cagtatacgt
    21241 acgtgtatct gtttttcctt tgattgttac ttctttggta cgtgttgcag gatcttctga
    21301 gatatcgatg acatcccctg ttacttctgt gatcactgct tgccctttcg gattacgtgc
    21361 ttcaaagatt tcttggacac gaggaagacc ttgagtgata tcgtctccgg caaccccacc
    21421 tgtatggaat gtacgcatcg tcaactgagt accaggttca ccgattgatt gagcggcgat
    21481 cgtaccaact gcttctccga cttcaacgtc agagccagtt gcaaggttgc gtccgtaaca
    21541 atgtttgcag acaccatgtt ttgtattaca tgtgaagaca gaacggattg tcactgtttc
    21601 gacacctgca tcaacgattt gttttgcgat gtcttcggaa atcaattggt ttcctgcaat
    21661 gatcaattca tttgtttcag gatgacgtac ttctttacgg gtgtaacgtc ccactaaacg
    21721 atcttctaat gattcgatga tttcatttcc ctcgcggatg gcttggattt caagacctcg
    21781 gtcagtaccg caatcttctt cacggatgat tacatcttgg gccacgtcaa ccagacgacg
    21841 agtcaagtaa cctgaatcgg cagtcttcaa ggctgtatcg gtcatccctt tacgagcccc
    21901 gtgagttgag ataaacattt ccaagacgga tagtccttca cggaagttcg aaatgattgg
    21961 caattccatg attcgaccat taggagcggc catcaaacca cgcattccgg caagctgtgt
    22021 aaagttggaa atgttaccac gagctccaga atcagacatc atgaagattg gatttttcgc
    22081 ttccaaacct tccatcagtt tttgttggat gctgtctttt gcagcattcc aaacagcaat
    22141 gacacgttca taacgttcgt catctgtgat cagaccacga cggaattgtt ttgtaatagt
    22201 ttcaacttgt ttatgggcat tttcaatgat ttcttgtttt tcattcagta cactgatgtc
    22261 agcgatccct actgtgatac cggcatgtgt cgaatgtttg taccctaagt ctttcatacg
    22321 gtcaagcatc ttagaagttt cttttacttt gaatcgtttg aagacttctg cgatgatgtt
    22381 tcctaagttt ttcttcttga acggtaatac taattcttgc tctttgatat gtgcaggaat
    22441 atcagtacca gcttcaacaa agtatttgtc cggtgtttgg acggtcaagt tgaagtctgt
    22501 tggttcattc agataaggga attcaggagg catgatctcg ttgaagatga tcttaccaac
    22561 tgttgtgatc atcgtacgtt ctttttgcca ttcagtaaat ggtttttcac ctaatgagtt
    22621 agggttcaca ccgatacgtg aatgtaaatg aacatatccg ttgcgccatg cgataacggc
    22681 ttcgttttga tctctgaaga ccattccttc gccttcgcgt ccttcttctt ccattgtcaa
    22741 gtagtagtta cctagaacca tatcttgaga aggagtaaca actggtttac catctttagg
    22801 gttcaagatg ttttgagcag ctaacatcaa catacgtgct tctgcttgtg cttcttcatt
    22861 caatggaacg tggacagcca tttggtctcc atcgaaatcg gcattataag cttcacatac
    22921 aagtggatgc aaacggattg cgcgtccttg tactaaaact ggttcgaatg cttggatacc
    22981 aagtcggtga agcgtaggtg cccggttcag caatactggg tgttccttga ttacgtcttc
    23041 taaaacatcc catacttcgt cttcttgacg ttcgatttta cgtttcgcat ttttgatgtt
    23101 tgaagctagt tcgcgttgaa caagctcacg catcacgaat ggtttgaata attcaatggc
    23161 catttctttt ggaagtccac attggtacat cttcaagaaa ggtccaacaa cgataacgga
    23221 acgacctgag tagtcgacac gtttacctag caagttttga cggaaacgac cttgtttccc
    23281 tttcaacata tgagaaagag atttcaatgg gcggttacct ggtccagtaa ctggacgtcc
    23341 gcgacgaccg ttatcgatca atgcatctac tgcttcttgc agcatacgtt tttcattttg
    23401 aacgatgatt ccaggtgcat tcaagtctaa caaacgtttc aaacggttat tacggttgat
    23461 tacacgacgg taaagatcat tcaagtcact tgttgcaaaa cgtccacctt ctaattgaac
    23521 cattgggcgt aaatctggtg gaataacagg gataacgtcc ataaccatcc agcttggttg
    23581 atttcctgaa gcgcggaatg cttctaaaat atccaaacgg cggattgcac gtgtacgttt
    23641 ttgtccttgt gcagatttca attcttcttt caattcggct gcttctgcat ctagatcaac
    23701 attatcaagt aattgtttaa tcgcttctgc acccatagca gcttggaatt cttgtccata
    23761 ttgttcacgt ttttcgcgat attcgcgttc tgtcaacaat tgttttttct ctaaattcgt
    23821 atttcctggt tcgatgacta catatgaagc aaaataaatg atttcttcca aagcgcgtgg
    23881 gctcatgtct aatacaagac ccatacgtga aggaatccct ttaaagtacc agatatgtga
    23941 aacaggagct gctaattcaa tatgtcccat gcgttcacgg cgaactttcg aacgagtaac
    24001 ttccactccg catcgatcac aaacgattcc tttataacgg atacgtttgt attttccgca
    24061 ggcacattcc cagtcttttg taggaccaaa aatccgctca cagaacaacc cttcgcgttc
    24121 aggttttaag gtacgatagt taatcgtctc aggttttttt acttcaccgt aagaccagct
    24181 tctgattttt tcgggagaag ccaaacctat ttgcatactt tcgaatttat ttacatcgat
    24241 caaaaggggt tccctccatt tcatttaatg gcaaaccgca agacggctga tcttcgaccg
    24301 ccttgcagct catagaccgg attagtctaa attatcttct gcggtttcaa agttttggat
    24361 gacatcgtct ttttcatctt ccacttgttc agcagctttc ttttctaatt ctttggcagt
    24421 ttgctgttcg gcaaattttg tcaaagcatc aacagtgatc aaatcgtcgt cttcatcgtc
    24481 catgtcgcga agttcgatct ctgtttcttc gatatccaag acacgcatgt ccagacctag
    24541 tgattgcaat tctttcacca atacgcggaa tgattccggt acacctggtt ttggaattgg
    24601 ttcacccttg acgattgctt cgtatgtttt cacacgtccg actacgtcat ctgatttgta
    24661 tgtcaagatt tcttgtaaag tataagccgc accgtaagct tccagtgccc atacttccat
    24721 ttcaccaaaa cgttgtccac caaattgagc tttacctccc aatggttgtt gtgtaaccaa
    24781 tgagtaaggt ccgattgaac gtgcatgcaa tttgtcatcg accatgtgag caagtttgat
    24841 catgtacatc acaccgacag acacacgtcc atcaaatggt tcacctgtac gtccgtcgta
    24901 cagaacagtt ttcgcatcgc tggccatacc ggcttcacga actgtttccc atacgtcttc
    24961 atcacttgca ccatcaaata ctggcgttgc tacgtggata cctaactgac gtgcagccat
    25021 acccaagtgt aattccaata cttgcccgat gttcatacgt gaaggcaccc ctaaaggatt
    25081 cagcatgata tcgattggtg ttccatcagg taggaatggc atatcttctt ccggcataat
    25141 acgggataca acccctttat ttccgtgacg accggccatt ttatcccctt catggatttt
    25201 acgtttttga acgatataaa cacgaactaa catgtttacg cctggtgaca attcatctcc
    25261 agcttcacga gtaaagattt tcacatcgtg aacgataccg ccgccgccat gtggtacacg
    25321 taatgatgta tcgcggactt cacgagcttt ttcgccaaag atcgcatgca atagacgttc
    25381 ttctgcagat aattctgtta ccccttttgg cgtgactttc cctacaagca aatcgccatc
    25441 ttggacttct gcaccaatac ggatgatacc catttcgtct aaatctttta atgcgtcttc
    25501 cccgacatta gggatttcgc gtgtgatttc ttcaggtcct aattttgtat cgcgggcttc
    25561 tgattcatat tcttcaatat ggatagaagt gtatacgtca tcttttacca aacgacggct
    25621 catgatgatc gcatcttcat agttgtaccc ttcccaagtc atgaaaccaa ctaaaacgtt
    25681 ttggcctaga gccatttcgc cttgttccat agatggtccg tctgccagag tatccccttt
    25741 ttcgactttc tcacccaaat gaacgattgg acgttggttg tagcttgttc cggagtttga
    25801 acgacggaat tttgttacat cgtatttatc taatgcaccg ttgtcgcggc gtacgcggat
    25861 ttcagaagca tcaacgtatt caacgacacc atcatgttta cataacaaag cagctcctga
    25921 gtcatgcgct gatttgtatt ccataccagt accaacccat ggtgcttgag gattgatcaa
    25981 cggcactgct tgacgctgca tgttggcacc catcaaggca cggttggagt catcgttttc
    26041 caagaaagga atacatgctg tcgcaacggc aactacttgt ttaggtgata cgtccatgta
    26101 gtctacttta tcaatagata cttctaagtt ttcactttga gcacgagcca taacaacgtc
    26161 ttgagcaaat gttccatctt cattcaatgg gctgtttgct tgggctacga tgtaatggtc
    26221 ttcgatatca gctgtcaagt agtcgatttg gtcagtaaca cgacctgttt cacggtctac
    26281 acgacgataa ggtgtttcga taaatccgaa tttatttact ttcgcataac tggacaaact
    26341 attgatcaac ccgatgtttg ggccttcagg agtttcgatc ggacacatac ggccatagtg
    26401 ggagtagtga acgtcacgaa cttcataacc ggcgcggtca cgagtcaatc cgccaggtcc
    26461 taaggcgaaa agacgacgtt tgtgtgtcaa ttcgccaaga gggtttgttt gatccatgaa
    26521 ctgtgacaac tgagaagaac caaagaattc tttgatactt gccacaactg gacggatatt
    26581 gatcaattgt tgaggtgtca atgtttcagt atcttggatc gacattcttt cacgaaccac
    26641 acgttccata cgtgctagcc cgatacggaa ttggttttgt aaaagttcac cgactgaacg
    26701 gatacgacga tttcctaagt ggtcgatatc atcgacattg ccgatacctt ccatcaagtt
    26761 caagaaatag ctcattgaag caatgatgtc ggctggacga accgttttta cagctgcttc
    26821 tggatagccg tttccgatca cgtttacttc acgttcaggg tctcttggtg aaaatacttt
    26881 gatgacttgg acagtcattg gatctgtgac cacaccgtct tctgatggat agtaagtcac
    26941 tgaatttagg ccattatcaa tgaaaggagc tagtgtttcc atgacttggt gagtcagaac
    27001 tgttcctttt tcaacgatga tctcgcctgt ttctggatca actaatgttt cagctaatgt
    27061 cagattcaat agacgtgttt tcaaatctaa ttttttgttt actttgtaac gaccaacgtt
    27121 tgctaagtcg taacgttttg gatcgaagaa acgagcattc agcaagttac gtgagctgtc
    27181 tgctgttttt ggttcgcctg gacgcaaacg ttcgtaaacg tctttcaaac cttcttctgt
    27241 tcttgagtcg cttgcgtttt tatgcaagtc tttttcgact gtattgcgta atgtttcgct
    27301 gtcgccgaag atttcaaaga tcgtatcatc ggaaccaaat cctaacgcac gaactaatac
    27361 ggttaaagga atcttacgtg tacggtcgat acgtacataa gagatgtctt ttgcatcagt
    27421 ttccatttct agccaagctc cacggttagg gataacagta gaaccgaatc cttcttttcc
    27481 gtttttgtcg acttttccat ggaaatagac acctggtgaa cggactaact gagaaacgat
    27541 tactcgctct gccccgttga tgatgaatgt tccttgttct gtcattaatg ggaaatcacc
    27601 gaagaatact tcttgtgctt tgatttcgcc agtctcgcgg tttgtcaaac gcaatgttac
    27661 atgtaatggt gcagagtagt ttgcatcatg cgcacgagct tctgctactg tatactttgg
    27721 ttctttcaat tcataatcta caaattccaa agatagattg ccattgaagt catcgattgg
    27781 caaaatgtct tcaaacattt ctctaagtcc ctcatctaag aaccattggt aagagtctgt
    27841 ttgaatttcg atcaaatttg gtaattccaa cacttcactg attcttgcga aacttctacg
    27901 ttcgcgatgt tttccgtatt ttactacgtg tccagccaag ctcttcaccc ctctaaaatg
    27961 tcattcaaaa agactacccg atcaattgtt acaataatat ttcaaatatt atttttaggt
    28021 aacaacagac attttttgcg gcttttaggc aaaaaaaaac caaaaataga acattctctt
    28081 gaaaccttac ttcgtgagct tctacttttg tttccttata ttaaagccga aacggacaat
    28141 atttcgtttc tgccttttct tcatcagata gtttttgcaa cttcatatac tacacttatt
    28201 ttctataaaa gtcaacactt cctggcgttt cttctgcttt ttcgcaacat tttcttaatg
    28261 ttttcaattt tatgttttca attatctgac aattcttaat tgacagacct ttttatctcg
    28321 gttatacttt agaaaattca ttttgtggag gaacttctat gcgaaccaac atcaaccaaa
    28381 tcgcaccaac acaactgaat aacttttact ttagctactt tagataggtt tgtattcatc
    28441 atgatggata caaacgttaa acgacagttt gtatctatga tggctaaaga actttgtatt
    28501 gcagcaaaaa gccacgtaga caaaatgcta agtggctgag cagtgaaaat acaaagtaaa
    28561 agtatcaagc attctacttt ttcaatttat tttccgactt ttcaatccat ttggacattt
    28621 tgtctgaatg gattttttgt ttcccaaaat taaggaggaa aaagaaatga aaaaaaatat
    28681 aatcatcgga ttaggcgctg ccctgctact agctttagga ggttgcgcac aaaaagacaa
    28741 ttccgcagag gcatcagatg gacaaaaaac aattggcgta ttgcaacttg tacaacataa
    28801 ctcgttagat gctgcctata aaggattcaa agaaggatta gcagaagaag ggtataaaga
    28861 aggcgataat ctaacaatcg attatcaaaa tgcccaaaac aatcaagaca acctgaaaag
    28921 tatgagtgag aaactcgtca aagaagatcc tgatttgcta cttggaatcg ccactccagc
    28981 agcacaatct ttattaaatg aaacaaccac tatcccgatg actgtcacag cggtcacaga
    29041 cttggaacaa gcccatttag tcacatccaa tgaaaaacct ggcggcaatg tgactggcac
    29101 gacagatatg gtgccaatcg aaaaacaaat cggcttactg ttaaatatcg tgccagacgc
    29161 caaaacaatc ggcatcatgt ataacaacgg tgaagcaaac tctaagatcc aagctgattt
    29221 ggcagaaaaa gaattgaaaa aagcgggcgt caaagtcaaa gtactgacag caaattccac
    29281 aaatgatgtc caacaagtga cgaaaagtct agctaaagat gtagatggaa tctatattcc
    29341 tactgataac acgttcgcaa gtgcggcaag tgttgtcggt gaagtcgcaa aagaaacaaa
    29401 aacacctgtc gttgctggcg cagttgatca agtcaaagac ggcggtctag caacagtagg
    29461 aatcgactac gaaagcttgg gcaaacaaac agggatcatg gcagcaaaaa tcttagacgg
    29521 caagaatcca agtgaacttc ctgtcgaaac agcgaatgat ttggaactgt atgtcaataa
    29581 agacatggcc aaagcattag gcatcaatcc agacagcatc aaagaagctg aataaaacac
    29641 aggaggattc tcatgacaaa tttgctctct cttttcttat catctgcatc gcaaggggtc
    29701 ttatgggccc tacttgcgat tggtgtatac gtcactttcc gtatcttgga cattgccgac
    29761 ttgactgctg aaggaagctt tcctttaggt gcagggatcg cggcagtaag tattacaaat
    29821 ggctatcatc cattgacagc ttgtcttcta ggctttttag ggagtgcggc agcagggctt
    29881 gtttccggac tgcttcacac aaaattgaaa attcccgccc ttcttgcagg gatcatcacc
    29941 atgactggtt tatattctgt cacatcccgt gtgatgggtg cgccgaacat ctctttattg
    30001 ggtcagccaa cgatctttca ttgggtcgag tcattcggca taacaaaaga caacgctgta
    30061 ctgatcgtcg gtctgctttt tgctttgatc gttgtatgtt tacttgtttt gttcttacgt
    30121 acagaaacag gacttgctat tcgtgcaact ggcgataatc tggcaatgag cgaagcaaac
    30181 gggatcaaca cagataatat gaagatcatc ggttatatga tttctaatgg atgcattgct
    30241 ctttctggct ccttgcttgc gcaaaacaac ggctttgctg atttaaattc tggtattgga
    30301 acgatcgtaa ttggacttgc ttctattatc atcgcagaag ttttgttacg taaccagcca
    30361 ctatttctcc gtctcttgac tgtcgtttta ggtgcggtca tttatcgttt tattttagcg
    30421 ttagtcttcg aactgaatgt tgaaccaagt gattcgaaac ttgcttctgc tttcgtgcta
    30481 gtgatctgtc tttctttccc gcagatccag caaaaattcc atttacctca aaaaaagaaa
    30541 ggcggtagtg tcaaatgaat gacgtcttaa cattggaaaa tctccatcat acctttgaaa
    30601 aaggaacgat caacgaaaat catgtcctga aaggcattaa tctttcctta gatcccggcg
    30661 acttcgtgac gatcatcggt ggaaatgggg ctggtaaatc tactttgctg aacagcatcg
    30721 ccggtacatt ttctgtcgat cagggtcaaa ttttattgaa tggaaaaaat atcacgaaaa
    30781 aatctgttgt cgaacgttcg aaatccatca gtcgcgtatt ccaagatcct aaactaggga
    30841 cagccgttcg tttaacggta gaagaaaatc ttgctcttgc tatgaaacga ggaaaaaaac
    30901 gcggcttctt ccgtggtgtc aaaccacaag accgaacatt tttcaaagac cagctggttc
    30961 ggctaaattt ggggttggaa aatcgtttat cctcagaaat cggtttgctg tctggaggac
    31021 aacgtcaagc tattacgtta ttgatggcca cattacagcg tccagaactg atcttattag
    31081 atgaacacac tgcagcgctt gaccctgcta cttccaaaac ggtgatggaa ttgacagaaa
    31141 agctgatcac tgagcagaat ctcactgctt ttatggtcac tcatgacatg gaagacgcga
    31201 tccgctatgg gagtcgactg atcatgctgc atcaaggaag gatcgtcgta gatatccagc
    31261 aagaggaaaa acagcagctc acagtgcccc aattattagc gttgttcaaa caaaacagcg
    31321 gcacggcatt aaaagacgat caagtacttt tatcttcata atcagaaaga ggatgggaca
    31381 aaaaatgaac gcccaccctc ttcttttttc tctttccttc tttcgttttt gctttatgta
    31441 tcaaccgttg tttcttcgaa aactattttg ttctctcctt cttcctgata gaatggatgg
    31501 gaaaggagct tgatgccatg acaacgaaag acaaggtact tcaattattg aaaaagacac
    31561 cagattttct ttccggagaa aagttggcac agcaactgga agtttcccgg acaagtattt
    31621 ggaaagccat caaagaattg gaaaaggcag gctatcgttt tgagcacggg cctacagggt
    31681 atcgttacct gccctctgac gtactagatg caaaagaaat ccagcaagag ctacggtcgt
    31741 ttattcctga tttgaaagta caaacgatga tgacttctga atctacgatg aaagatgcca
    31801 aactggcagc agctcaagga gattctgttt cgaagttatt tgttgctgat acacaagaac
    31861 aagctcgtgg acgttttgga cggccttttt tcgctgaacc tggacgagga atctacatga
    31921 gtctcttgct ccatccagac aaacggtttg atgaattgcc tcaatatacg atcatcgcag
    31981 ccagtgcctg tgtgaaagcc attgaatctg taaccggtcg ttctgcttcg atcaaatggg
    32041 tcaatgatat ctacatggat ggaaaaaaag tctgtgggat tttatctgaa gcagtcagtg
    32101 atatggaaag cggcaggatc agtcatatca tcattgggat cgggcttaat ttttctgttc
    32161 ctcaaaatca ttttccagct gatctccaag aaaaagccat ctctgtcttt cccgacggac
    32221 aagctagtgt cacaaggaat cagctaatca gcaaaatctg gcaagaattg ttcacttatc
    32281 tttctcaccc agaaaaagcg ttggacttct ataaagaaaa atcattcgta ttgggaaaaa
    32341 ccgtgtcgtt caatcaaaaa ggaacgactt atgtcggtct tgcaaaagaa atcggtgatc
    32401 atggcgaact gatcgtccaa acaaatgaac agaagatgag tttgtcttct ggcgaaatca
    32461 gtctcacatc tatccgtacg caataattat cagatttcac aaaaggacac ctgatctcat
    32521 acagtgtcct tttttctgaa ttctcttcaa aagactctcc ttattctatc agctgacagt
    32581 ttctctatcc tctagaaaaa ggtattctaa aaatatctat aaagcatggt acactttctt
    32641 taaatgaatc aatgcaaaaa acaagagagt catcagttta cacgatcaaa agagatagca
    32701 ggccgcttcc tttttcaatc ttatagatag accatgggta acgataaaaa caaaaaagaa
    32761 cttgcgactt attttgccgt aagttctttt ttagctagtg ccttaatctc ttaatcccaa
    32821 caaacgtctc gcatagatca cctgaccaga gtgcatagca gcatcatcaa taatagaaac
    32881 gagacgcatt cctcgtgtga ctggtggtgt ccagttctcg tcaattactt catctagctc
    32941 ggaaggttcc agccttctta agtaagaaat agcaaaatca gcagctcctc gcaagtatcc
    33001 tagcagatct tctatttgat tagcttggat ctgctttgct tgttccagac tatgcttcca
    33061 atcttgttcg ttatctgcta tcgtcatcgg aaaccggctt tcccagtctt gactatgcca
    33121 aattggagaa gttcctgcta aatcagcaat ctggaaatct aattctcgag cggtatgcca
    33181 agccagccaa gtcattgatt tgatctgcgg ggctctatct tccactggaa aacgattggc
    33241 ctcctcaata gagacgcctt caaacaaacg ttcaaaccga tcgtatgccc gatccacact
    33301 ctcgcatagc atatctaaat aatccattta ttttcctcct ttttatttat cctacttact
    33361 ttttcctaat tctaggatac ctacttatat gttactacac acccttattt tttacacttt
    33421 aacagtcacc atcatcaata gtttggagat tgaaagaaaa agatagtgtc gaactatcaa
    33481 ttgaacaaga agcaacaata tgaacgtttc attaatattc tttaaataaa caatgatttt
    33541 tcaaacgaac agtttaagac taggagaaaa agagtataat aggaaaatgt ttgaaaggaa
    33601 aggaagggga aaaatgaaaa aaagggcaag tttactagtc ctagttgctt tgttgttcaa
    33661 tatcttttcg tatggtgtgg ccgtttcagc ggaaacatac attcctaaag accctgggaa
    33721 tatttataat gatctaactg gtaactatgg cttgttagga attgctagtc aattccacgt
    33781 atttgctaaa aataagacaa ctgtgaatgc acatacagac ggaaatatag caacacatga
    33841 acttgatgca aaaaataatt ttggtacaga gcttcatgaa ggtttattga accaagaaat
    33901 aaattatata caaaaaactg attctttcgc taattcttca ggcataccta caggtagcac
    33961 aagaatgaat aaatttgtcg ttggcagtaa cgtggatgta gcacttcaag atggtcatcc
    34021 tacagtcaat ggatccaggc ttgatcactt aactccagat gatttttata aagatcgtgc
    34081 tgggcatgaa tatattgatt tcgagcagga atttgctaaa ttgaatgtag cagcaaatga
    34141 tcttgcaacg atcactccag ctaaaacata tactgctgca gattttccag acatgaacaa
    34201 tcggacaatc gatttaactg atttatcaga taccgggttt ttattggtaa atatcgatgc
    34261 agaagtgtta acgatgaata cgccacttca aatcattaat ccaaatgatc aagtagttgt
    34321 atttaatgtc atcaacagtt cttctgcatt gaacgtacag tcaccaatca aatacaatga
    34381 tcgttcaaat catgaaacag aagatttttc ggatgcgaat atctcttgga attttggaaa
    34441 tgagatgact gatttgacaa tcagtgctcc ttttcaagga acaatccttg cgcctaatgc
    34501 tactatccgc attactcaaa accaagacgg aacgattata ggaacaaatg tgattttaga
    34561 tgcagctacc aatcgttggg atcctaacga aatatttatc agcgacaatg gtacagatac
    34621 gacagacaca agcgacagta cagatacatc taccacaagt gatagctcag attcatcaac
    34681 ttcaagcgac agtacagata ctacctctac cacaagtgat agcacggata catcagcttc
    34741 aagcgacagt acagatacta cctctaccac aagtgatagc acggacacat cagcttcaag
    34801 tgacagtaca gatactacct ctaccacaag tgacagcacg gacacgtcag cttcaagcga
    34861 cagtacagat actacctcta ccacaagtga tagcacggac acatcagctt caagtgacag
    34921 tacagatact acctctacca caagtgatag cacggacacg tcagcttcaa gtgacagtac
    34981 agatactacc tctaccacaa gtgatagctc agattcatct accactacaa gtgatagcac
    35041 ggacacgtca gcttcaagtg acagtacaga tacatcctct accacaagtg atagctcaga
    35101 ttcatcaact tcaagcgata gtacagacac gtcgtctacc acaagcgata cacgtcatgc
    35161 aagtgtctcc ttctcaaaaa caagttcgga taacaggacg aactttaact taactaataa
    35221 aacaagcaat gacaatggaa acaaatcaaa aagagcactt cctaaaactg gaagtcaatc
    35281 gaataattgg ataacactcg caggcgttat attacttgta atcggtttaa gaatcacttt
    35341 tatgagttat aagaaatcga aaaggtaaaa aaatattcaa gataaaaaag agcaacgtcg
    35401 ctaacggacg ttgctcttta tttttgcttt ttatcataaa tacaagaact acaattcaat
    35461 ttgtcaaaaa acacgtagat ttccttctga gaaatttatt tacgtatcga acctttccct
    35521 attcagtctt tgcgatccaa aatcagttgg gtaagggaaa agagattctc ttttgttcga
    35581 agagaggtgg caggtaattt ctttatttcc ttcaaagcct tttctgtgta agaggccgct
    35641 aacttcctag cttcttccac gcctcctgta tgttcaacga ttttgcgtac ggcgtcgaca
    35701 tcttcttctg tcattgccgc tttcttctct aaataaggta gtagctttgg tttgtttttt
    35761 tgcaaagagt agatcaacgg taaagaatag accccttgac gcatgtcttc tagtacaggt
    35821 ttgccgattt cctggctctc ttttgtataa tctaaaatat catcgataat ctgaaaggcc
    35881 atcccgatag aaagtccgat atctcctgct ttttttgcga agcgctcgct tgttccactt
    35941 tcaaaagcgc caacagaaca acttaattgg aacagttcag ctgtcttacc tgaaatattt
    36001 tccaaatatt cttttacaga aagttcataa ttatagcgat catccatctg ccctaattcg
    36061 ccattcaata ctttttccat actgcgagaa ttcaattgga gacttttcaa ggaagtggag
    36121 taatcagaca atagtttaaa acagcagaca aataaatagt ctcctgcata gacagaaacg
    36181 acattaccaa actgactacg gatattaggc tgaccacgtc gcagatccgc ttcatcaacg
    36241 atatcatcat ggatcagtgt ggccgtatgg agcatttcga tagaagctgc caaagcgatg
    36301 gctttgtctc gatcttgctc tggtccaaat tgtgagaaca atagctgata ggcaggacgc
    36361 aacagctttc cgccggcatg gatcgtttct ttgattgctt gttcgacagg tttgtttttc
    36421 aggcggacag tttcttccat ccgttttagt gtttctgtca attctttact taaagcagga
    36481 tagttttccc acattggatg tagcttcata aaaaaactcc ttgtgtgacg attatttttt
    36541 ggtaaacatt gggctccatt tttgtttggt tccctgctca taatcttttt ggaatcgttg
    36601 aagtgtctgc acatgtcgta aaagataatt cgctgcgatc ccgattgcaa tccctgataa
    36661 aatccctaaa actgaaagga ctggcaagta caacatgact gtccatgatt gtgcaatgaa
    36721 agaagccatc aaaagctgtc cgacattatg catgaaaccg ccggccgcac taattccgat
    36781 gatactgaca cgttttggtc ctaattgctt gaccaataac attccaaaat aactaagcaa
    36841 agcaccactc atactataaa ggaatgtgga aatcgttccg cctagcaaag tagtcaggaa
    36901 tagtcgtagc caaagtagta agaagctgtc ttgttttttc atggtaaaaa tggcaacgat
    36961 cgtgattaga ttggctaagc ctagttttgc accaggcgca aaagaaaaag gataagggat
    37021 catattttcc aataaaccaa tgatcactcc ttgtgcaaca agtagcgaaa tataaatcat
    37081 tttttgtaat ttactcatgg tgtgtaaagg tctaataaat cagactgtct tcgtcacctc
    37141 catctgttga acggacttcg atcactaatt tatgtggcaa acagacgatg gtttcgccat
    37201 ttttcgttgc ccagcctcga cgtacgcaga tctggtcatc gcaatctgct tcttttatcc
    37261 gtactcgatc gccatctatc tcgatcaagt tataatctcc gtgttcatct ttgtaagtat
    37321 atgtgttgct ctcttctcca gccatcaaag ggaatgtttt gatttctgtg ccatccacac
    37381 gcagtaccgc ttctttttct gctgttgcgg tgttttgctg aagaccaaaa atcatgactg
    37441 gtaaaaaaga aagaacagtc aaaagcaaaa taataaaaac atcccaaggt ttgagcagac
    37501 ttttttcagc aaattcttta aggctcattt ttgttctcct ttttccagat taactcaccc
    37561 aattttagca taaaaacaag aggttgtgac acctgtgtct tgctttgagt aataagaacg
    37621 aagaatagaa aacagctttc catgttttct aattctttgg gcttattacc gagaagcagc
    37681 aggtggaaca ccgtttataa caagaggttg tgacagaagt gggcaacttc aagaaataag
    37741 aaggaattta cgaaaattac ttttcaagtt tttgtgaaat ttcggcttat ttttcgaaga
    37801 agctacttct ggaacaccgt ttataacaag aggttgtaac agaggttgtg acacctgtgt
    37861 cttgctcatg gaggcttatc tcgggcatct tattccttta attttacata aaaaggaggc
    37921 tgtgacggtt tgtctcagcc cctttctatt gaaatcttgc attcaaataa cgttctttat
    37981 ctatttattt cttgccgtac tgggaacttg gtctaccgta ccaccaatta cctagtgtac
    38041 gttgtagcca tggaattacc cagcgatcca acccaatcgc acgtccggaa ccgttcatca
    38101 atgcgaaagc aacaaaaatg aaccaaatgt ttacccagta aaacatgcct gataagcaga
    38161 acgtgatcac caatacaatc gttgtcgcac tgcatagcca tgtgaataat ccagcaatca
    38221 atgctaatgc caaggcaatt tcaaagaata ccatgaattt ttggaagaac attgctacat
    38281 cattgtttgg catgatcact tgcatgatct ttgtgaacca gtctggtgac ttctcaatca
    38341 cagccattgg ttcttcaccg tatgcataac tcaaaccaaa atgtgcagct tgagtcgctg
    38401 cttctccggc acttgcccct gctccgctgg cagctgtggt tgcatcacca gcagcagaag
    38461 caccactggc aacatctgtt acattgtatt cccatgtcca agggaacaca ctgtttccag
    38521 tgaaccatga tccttcacca aaccaagtac ttggtttgaa cacttcacca ttcccaatga
    38581 tttttttgga agcttcaacg aaccaaacta aaccatagaa aatacgaagt ggcacactcc
    38641 ataagacatt gccgtaacga gaagaatgtc ctcgagtcac gttgcgatca tctttgatat
    38701 ggaaaaactc atgcattaaa tattggaaca tataataacc agaacgaata tcaaagaagt
    38761 atttcaaatt cacgatatgt ttcattacga tagctaaaaa tccgcttaaa tggatcttat
    38821 caaataggtt agctaccccc catttggcac caatagaaac cataaatcct tgatagtttc
    38881 ctttaaattt atgcttttct ccgcctttga tcgaagccac gatattcgct gcggctgtgt
    38941 gtcctgtttg ttcagcagct tgaacgatct gcggtgtcgg tgttcctggg aattcttcat
    39001 aaaagactaa atcaccaatg atatagatgt ttttatcttc gtagcctttt gcctgcatat
    39061 attcattggc gatcaaccgc tgtccgcgtg ctgattctaa tccaaagtca gcagcgtcag
    39121 aagttccttt gacaccagct gtccaaatca gtgtgtgagt cggaatgttg cgtccgtctt
    39181 tcaatttgat atgatcagca gccacttcta cgattggtgc attcaataat aattccacgt
    39241 tgtgcttacg caaatagcgt tcagcttttg cagcatcatt tcgatccaac atattcaaga
    39301 tcgtcggcat tgcctctacg accatcagtg tgatttcgtt tggatctaat ttataatctt
    39361 tggctaggcg atttttccag tcgatcagtt ccccaatcat ttcaataccg gtaaatccag
    39421 aaccacagac aacgaaagtc agcatggctt tacgcagttc atcatctggt tccaatgcag
    39481 cttttgctac tgtcttctca atatgttccc gaatccttac agaatcttca aatgaccaaa
    39541 gggtgaatcc gtgtgctttg acaccaggtg taccaaagtc attcggctct ccgcccattc
    39601 caaggatcag ctgatcaaaa ggataggaac ctaatttggt cttgacgatt tttcgttctt
    39661 tatcgatacc gattacagtg tctgtgacaa gttgtacatt cttttgacga gcaaacaaat
    39721 gctgcagatc gtattggatt gcttctggtt ctacacgtcc gccagctact tcatgcaact
    39781 cggtcatcat agtatggtac gaatgacgat cgatcagagt aattgctaca tcttcttttt
    39841 tcagtttctt tgccaagtat tttgtagctg aaacaccggc atatcctgct cctacaacga
    39901 caatattttg ctttgccatt gatcatccgc tccttataga ctatctatat aatgaatata
    39961 tgataattct tttagtttga tacttattac acaatctcca tatattatat agatgttctg
    40021 ttcttttgtc taactccttt tggatttttt tcaaatttta aaataaagcg ttttttcacg
    40081 aaatttgctg aaagaaaacg tttgaaatat tacatgggtt atttatcaaa aatagttgac
    40141 ttataggcta aaaagattag aatgtataat gaatcacaaa gaaaaattgt ggactagaaa
    40201 tggaatggtg gggtattaaa atgaagaaaa aacgttttgt aactggattt gccgtattag
    40261 cattttcagc tctagtgtta ggcgcttgcg gcgcagatga caacggaagc tcaaactctt
    40321 cttctgaatc atctacagca caatcttcga ctgcaaaaag cacaacagaa tcatctgcaa
    40381 aagttgtagc tggcggagat ttgcaagacg gcacatataa attagaagaa aaaaattatt
    40441 caaatggtta ccgtgcagtc tttgaaatgg ttgtaaaaga cggcaaaatc actgaatcaa
    40501 aatatgataa cgtcaatgaa aacggcgaat caaaaacaaa agatgcagaa tacaacaaaa
    40561 acatggaagc aaaatctggc acaaacccag aaaaatacat tcctgagttg aatgaccaat
    40621 tcttaaaagc acaaagcgca agcggtgtgg aagtcgtaac tggagctact cactcatctg
    40681 aaagcttcca aaactacgca caacaattga tccaagctgc tcaagctggt aacacagata
    40741 caatcgaaat cgacaatggt gctgatttga aagacggcac ttacaagctt gaagaaaaga
    40801 actactctaa cggctaccgt gtgcaattcg aaatgacagt tgctggcggc aaagtaactg
    40861 aatcaaactt tgattatatc gacaaagacg gtaaatcaaa acaagatgat acagaatata
    40921 atgaaaatat gaaagcaaaa agcggtacag aaccaaaaac ttacatccct actctgaacg
    40981 acgaattcgt caaagcaatg ggcgaagaag atggctcacc tgctaatgta gaagttgtta
    41041 caggtgctac acacagctca cattcattca tcatgtacgc acaacaatta gtgaatgcag
    41101 ctgaaaaagg cgacactcaa acaatcgaag tagataatat cgtaacagaa aaataatcac
    41161 ataatcatac taataaaagt tggagggtgg gacgatagcc agattaggca gtcgtctcac
    41221 ctttcaaaat gaagagagga aaaagatgcg gaaaaaacta ctattttcct taatcacact
    41281 gggcatctct tttatggtgc taactggctg cagcaactca gcaaataaaa caaccactga
    41341 aagttcagca gctaccaaga tattgaaaga tccatattct gatgaacagt tcttgttagg
    41401 gacttacgtt cgtatccgtg tgtatgatga aggcaaagaa tcagcattga aacctgcctt
    41461 cgatcgagta aaagaacttg gtgataaaat cacgatcaat caaaaaggtt ctgagatcga
    41521 tgaagtgaat gagcaagctg ggatcaaacc agtaaaagtt tctgatgacg tctacacgtt
    41581 agtcaagcgg gcctacgaat atagccaaga ttctcaaggc ggattcgata tggcgattgg
    41641 tgcaatcaca caattatggc gaatcggttt tgatgacgcc agaaaacctt cccaagaaga
    41701 aatcgatcag gcattgaaat tagtggatta tcataagatc gaactaaatg acaaagaaaa
    41761 aactgtttat ctaaaagaaa aaggaatgat catcgattta ggtgcaatcg ccaaaggtta
    41821 cattacggac gaagtagtga aagtcttgaa aaaacaagga gtgaccactg ccatcgttga
    41881 cttgggcggt aatgtctatg tcttaggcca cagcccaaga ggcgaaaacc aagactggac
    41941 agtcggcatc caagatccga acatggctcg cggatctgtt ttaggttcta ttaaagaacg
    42001 gaacaaaaca ttagttacct ctggaattta cgagcgttat ttagaagtag atggcaaaaa
    42061 ataccatcat ttgtttgatc caaaaacggg ttatccgttc gacaatgata tcgcaagtgt
    42121 cacgatcata acagataaat caattgatgg tgacgggttg tctacagcag tcttttcaat
    42181 gggtgtgaaa aaaggactgg aatacgtcga aagcgaattg aataacggga cggaagcgat
    42241 cttcgtgaca aaagacgata aagtatatgt gaccgatcca atcaaagaca ccttcaaatt
    42301 atcggaggac tcccattaca cgatgggtga ccgttctgaa ctaaaataag gagtacgaac
    42361 catgacacta aaaatctttt tagaagtagt tgaaatacga acaaaggtgg ctagtgtatt
    42421 tccttttgcg gtaggggtat tattctctat cgcttttttt catgagatac attggctaaa
    42481 cactttttta ttttttattg gaatgctagt ttttgattta gcgactaccg ctatcaataa
    42541 ttacatggat tatgaaaagg ctcattctga agtatataag tatgaagaaa atgtcattgg
    42601 ccgcagaaat ctatctcctg tattgattcg aaacatgatt ttagctatga ttgcatttgt
    42661 ttttgttatc ggcgttattc taacgatcaa tacgggttgg cttttacttt tgatgggatt
    42721 tatctgttgt tttattggag tattctatac attcggaccg attcctttat ctcgaatgcc
    42781 tttaggggaa attttcagtg gggtgactat gggccttgga atttttgcca tggtcgttta
    42841 tgtcaataca ttcggttcag atgtctatga tctgacagtc aacttttcat ctggacaatt
    42901 tgctttggta ggaaatcttt gggctatagc agcaatcgta ttagcttcct tacccttggt
    42961 gtttacgatt gccaatatca tgttggctaa taatttgcgg gatcttgacc gtgatattga
    43021 aaatcatcgc tatacactag ttttttatat cggacgtcct gcgggaacag tcttattcca
    43081 gctattgatg tatgcttgct atttcgtgat tttaatgggg ttgttgagcg gtatctatga
    43141 atggccgatc ttggtcacct tcttgacctt gccaattgtg aagaagcatt tggatcaatt
    43201 caagcaaacg ttaccccagc ctatcagttt cagctattcc atcaaaaata tggtcttatt
    43261 caatgccagt tatgtattgg ggctattact aacaatcatt atgcaagcca tttaacagca
    43321 tgaagaggtt gtgaaaaaac tgccctgcat caagtaataa gaacagccaa ataaaaatag
    43381 ctccttatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    43441 ttatcaggag gttgtgaaaa agtcgcttag tttcgagtat taagaaaaat tttgtgaaaa
    43501 tggctttcca catttttgca taaatttggc ttaataccga gaaactggct tttgaacacc
    43561 gtttatcaga ggttgtgaaa aagtcgctta gtttcgagta ttaagaaaaa ttttgtgaaa
    43621 atggctttcc acatttttgc ataaatttgg cttaataccg agaaactggc ttttgaacac
    43681 cgtttatcag aggttgtaaa atcagtgttt tgtcctgagt attagagaaa caaatggaaa
    43741 aatagttcct catattttgc cgttttttga gctaataccg aaggacagct gattgaacac
    43801 tatttgttcg gaaaaagtga ctaactatga cacaattttt ttcacagtcc cttttttcac
    43861 ttgatttgat tcgtaccagc gaacttgacg agaactttct tggtttggta actatatggt
    43921 attcttttaa catcctcgtt tgcttcttct aatttattta tacaaagtca cactttttta
    43981 aacatctgtt cttcgataca tttctatttc ttttaaacat cgataccaat attttgaact
    44041 taagagtgca taccaaatgg attcatttac tcttcgtcag ttacgaagat aatcaaaatc
    44101 tccaacttcc ctacttattt cgttttgaga attatcgaag caatcttaca taaataacta
    44161 aaaaacaaaa aaccagaaaa tcagtatact gattttctgg ttttacatgg tttgttcaat
    44221 aaaaagctgt tggaactgtt aatattaaat tatcgcatcg ttacgaattc ttccgctcct
    44281 gttggatgga tggctactgt attgtcaaag tcttctttag ttgcacccat cttgatagcc
    44341 acggcaaaac cttgcagcat ctcatcgaca ccaacaccaa tagcatgtaa gccgacgatt
    44401 ctttcttctt ttccgacaca gatcaatttc atttcgcatt tttggcgata atcatttaat
    44461 gcaaagtaca ttggggtaaa gcgtgaacga taaactttca attcattttc gccatatttt
    44521 tccaatgctt cttcttctgt caaaccaatt gttgcaattg gtggatgcgt aaagacgact
    44581 gtcggaacaa gtttatagtc aagataagaa tctttctttc cattaaataa acgttctgat
    44641 aaacgtctac cagctgcgat tgcaacagga gtcagatcta atttaccgat cacatcacca
    44701 acagcaaaaa tatgttcatc cgttgtattt tggtatttat ctactttgat aaaccctttt
    44761 ttgtccaatt ccacatttgt attttccaga cctaattttt cggtattcgg tacacgtcca
    44821 ccggcaaaaa gtacacaatc accagttaag gtttcaccat tttcaaatag caccgtatat
    44881 tcgtcattgt ttttagtaat ttctttagca atatgatgtg cgtaagtttt tattccagct
    44941 tcttggtaca tttggatcaa attgtccgaa agcattttat caaacgttct aagtggtcgt
    45001 tcttttcgat atgcccacat gacttcacta cctaaaccac gaaatacacc tgaaagttca
    45061 gccgcaatgt atccagcacc taaaacgatt gctctcttag gtaactctgt taattcaaaa
    45121 aatccatttg aatcaattgc gtattctcca ccaggaatgg tcattttact tgcacggcct
    45181 ccagtagcga tcaagatttt aggagcacga taggtttcac cgtttacttc gatcgtttga
    45241 ctatcgataa aagtagcgta accttttata gcctcgacat gattgctatc taatcctctt
    45301 tgataagcac cgtgtagaaa atcaatatat ttttctcgtc tttctactag accggcgaaa
    45361 tcaacatttt ttaaatctgc ttggataccg taacttgagg catctcgttc aattgtttcc
    45421 aaaatcgtac ttgcttgcca cataactttt ttaggtacac aaccgacgtt gacacatgtt
    45481 ccgcccaatt cattcgcttc aatcagcaaa acttttgcgc catgcatccc tgctctgttt
    45541 gctgaagcaa taccgccaga gccgccacca attacgatgt aatcatatat ttgcattttg
    45601 ttcctcctta ttgaagagat caatcaaaac ctttatttaa cgatcctttt tctacagaaa
    45661 acaagtgtaa cacttttctt gaattttgta tgcgaagatg cttaaaacag ggatatatca
    45721 gctttttcct tatttacgtt ttcggatcat atctccaggt ttcaccggct gtgcgactgg
    45781 catagttaaa atcatcattg gatttggtgc tcggtcaatg gattcgcctt cttcattatg
    45841 cataacttca acggtttgac tgaaatgact gaatcctgga ccataaaatt cgatttcatc
    45901 tcctacagaa aacaagtttc tctgacgtat cgtagcaatc tgtgttgcct catcataaga
    45961 taatacttca ccgacaaatt tatatactgg gattttacga cgttcaccga ataattgttc
    46021 gttttcagtt ggtgtattgt agtaaaaacc tgtagctaat tctcgttgtg ctactttcca
    46081 taactcgtcg atccattctt gcttgcagac atagttttca ggatcttcca tataactgtc
    46141 tacagccgct ttatagacat ttgacaccgt agatacataa tggatcgatt tcattcttcc
    46201 ttcgatcttg aagctgtcta cgccgttttc aatcaattct ggaatatgtt cgatcattga
    46261 catatccact gcactcatcg agaattcttc ttccacttcg cctgtatcag ttaaactgtt
    46321 tcgttcttga ccaaaaggca tatcgaacaa tccatacttc cagcgacaag attgagaaca
    46381 tccgccacgg tttgcatccc gcatcgacat atggttggac aatgtgcatc gaccagaata
    46441 agagatacac atggcaccat ggataaatgc ttcgatttcg gtatccgtat ttttacgaat
    46501 ctctgccact tcctccattg aaacttcacg agctaaaacg acacgttcca acccttcttc
    46561 tttccagaat tccaatgtct caaaattagt tgctgaagct tgagtggata aatggatcgg
    46621 cagacctggg gcttctgtcg cacaaatttc gatcaaagct ggatcagaaa caatcactgc
    46681 agaaataccg acatcacgca aactgcggaa aaattcccct gctccatctt catttccttc
    46741 atgggtgacc atattagcag caacgtatac cttcgcatca tgttcttttg caaaagcaac
    46801 tccttcagcc atttcttcat aagtaaaatt acctgcacgg cttcttaaac catatgcatt
    46861 cccgccaata tatactgcat ctgctccata atggatcgcg gtttttaact tttccagtgt
    46921 tcctgctggc gctaggattt ctggtcgttt caattttctt tttactgtca tttctttcat
    46981 catactcctt atttgatagc agaaggatca atataaaaga atcctgtatc taattcacgg
    47041 ttttcaggat gcaatttact gatttcgcta gtcatttttt ccgctttttc ttgatcccag
    47101 ctaccttcta aaatttgttt ttttgcttcg gcgaatagtc gagtgatgtt tacgaatttt
    47161 tcgcctggag taaataatcc gtccaatttc catgtacagt aatgatgctg ataaagttca
    47221 ttcaattcat tcgagagatt cagatcattg ctggcaaaaa tatgtgtgcc atgactatct
    47281 tcataaatag aataatgtgt ctcttctttt ttaggttccg agataaaaag acctctttca
    47341 cgatcttttt gttcgtcttg tttcgtatag ttatagtaat tctgtagcag tggacgtttg
    47401 gattgatgga tgcatgtagc accatacaca agggtttcta caggaatatc gagtttttct
    47461 tccatcgcct tcatctcttc aaaaggaact tcacgagcaa gtactgctcc aactgcgcct
    47521 tttttcgccc agaaattgat ttgacgtgcg ctcgttacta atgtttcagc atcataaata
    47581 tacggtatac gcaattcagg attttttttc atcgtataaa taatacctgt atcaccaact
    47641 gtgatcacat ctacgtttat ttctttaaaa aaagccaaat attcaggtac atttttcatt
    47701 ttttcaggat gaatgatccc atttacagca atattcgctt ttttaccata cttgtgtgct
    47761 aattctacca attgtcgctg ttcttctcgt gtaaatgaag caggcagacg caatccaaat
    47821 tgctcttcac cgaaatatag tgtatctgca cctgcagcaa gcaactgttc tgcttgttca
    47881 atagtttcta ctgtggttat gagttcgatc ataattttct cctcctacaa cttcataata
    47941 gtagcatagc tctaaaaact ttccaatact tcttctattt aaagtcggat ttttgaaaat
    48001 tatttcacaa aaaatcaaaa taaagttcga tatattctgt ccaaatataa aaagagattg
    48061 tgacaaaaat cttgtcacaa cctcttaatc aagtcttact attataaaaa ttcagctaca
    48121 caggccaagt aactataggg aacctactgt ttccttttta ggtccgcgaa cattcaatgt
    48181 gatcttacct tttgaagcac ctactgttac gtggtcacct aaacgaattt ctccgccaag
    48241 caaagcctcg ctcaatcgat cttcaatttc tttttgaagt gcgcgacgga ttggacgtgc
    48301 accatattca ggatcaaatc cagctttccc gatcacatcg attgcagatg gtgtgatttt
    48361 cacttgaata tcttgttctt tcaatcgttt gataatcgct ttgctcatga tttggacgat
    48421 tgtatggatt tcatctttac tcaatgaatg gaagacgaca gtctcatcga ttcgattcaa
    48481 gaattcaggt cggaaagctt tctttaactc ttctaagata cgtttttgca tggctttgtg
    48541 atctttagta acatcttgga cattgaatcc gacatttttt tcttctcgaa tttgtgtcgc
    48601 tccgatattt gaagtcataa tcatgattgt atttctaaag tccacttttc tacctttaga
    48661 atctgttaaa tgaccatcat ccaatacttg cagaagtaaa ttgaaaacgt ctggatgtgc
    48721 tttctccact tcatctaaga gaatcactga atatggtttt tgacgaattt tttctgtcaa
    48781 ctgtccacct tcatcatacc ctacgtatcc tggaggagac ccgattaatc ggcttgtact
    48841 gtatttttcc ataaattctg acatatcaac acggatcagg gcatcttcac ttccaaacat
    48901 gacttctgaa agtgctttgg ccaattctgt ttttccgaca ccagttggtc caaggaacat
    48961 gaatgaacca attggacgat caggatcttt caatccgctt cgtgcacggc ggatcgcacg
    49021 tgaaactgct ttgacagcct catcttgacc aacgacacgt tcatgcagaa gtccttccag
    49081 ttctaacaag cgttcgcttt cttttttctc caactgctgt agagggacac cagtccactc
    49141 cgatacaact gtagcaacat cttcttctgt tacacgatca gaataacctt gctcctgttt
    49201 tgcttcaatt gcagaaactt tttgcagctt tttacgtagt gctttttctt gtctgcgtaa
    49261 ttgagcagca ttttcaaagt cttgtttttg gatcgctgct tccttttctt gtactagttc
    49321 atcgatttct agtttgatca cagttgattt tgttaagtga tcggtttgat ccaaacggac
    49381 tttcgctgct gattcatcga tcaaatcaat tgctttatcg ggtagttgac gagaagtgat
    49441 ataacgaaca gaaagattga ctgctgctcg tacagcttca tctgtgatct ccactccatg
    49501 gtgctcttca tatcttgtac gtaatccttg aagaatcact tctgcttctt caggagttgg
    49561 ctcatctact tgaatgcgag caaaacgtcg ctctaatgca gaatcttttt cgatatattt
    49621 ttgatattca tctagggtcg ttgctccgat cgtttgtaat tctcctcgag ctaacgccgg
    49681 tttcaagata ttcgaagcat caattgctcc ttctgctcca cctgcaccaa ttaaggtatg
    49741 caattcatca atgaataaga ttacttgacc atcattatag atttcgtcga tgaccttttt
    49801 cattcgatct tcaaattcac cgcgatattt cgtaccagca accaaagatc ccatatcaag
    49861 catcatcagg cgcttttctt gcatgtcttc tggcacttca cctaaaatga ttttttgagc
    49921 taacccttca gcaatggctg ttttgcctac accaggttca cccaccagta cagggttatt
    49981 ctttgtccgt cggctaagaa tctggataag ccgtttcact tctctcgaac gaccaacaac
    50041 tgggtccagc ttgttttctt ttgctaattt cgtcaaatca cgtgctaatg aatctagcgt
    50101 aggtgttcct tgcggtgttt gccgtttatc ttgtacattt acatttctac gacgattcat
    50161 tccttttcca gcagaatcac cagctagccc cattttttgt ttcagaactt gacgggcttt
    50221 tgaaaggctg atacctaagt tgatcatgat tcgagtagcc atgatacttt catcttttaa
    50281 taagctcatc aaaatatgtt ctgttccaac tttttgagaa ccagttttct tcacttcgct
    50341 gctagctaaa gcaaaaactt gtttcattct tggtgaatat ggaagaaaga ctcctttagg
    50401 gtaagaacgg ataccaccat aaccaatcag atgttcaatt tcttcataaa tttccgtttc
    50461 attcaaatcc atttcacgta atacttttcc agcaattcca ttttgctcga ccactaaggc
    50521 tagtaaaaca tgttctgaac taactgattg atgtttcaac cgttttgctt cttcttgtgc
    50581 aatttctaat actgcttggg ctctttcagt aaaaagttct tccatctaat ctcacttccc
    50641 atcttcataa cttaaacgtt ccagaaatgc tcggagaatc cgagcacgtg tatgatcttc
    50701 atattcattg aaattcaatg tgttttttgc aattgcactc aacatcaagt ttccttcttt
    50761 ttttgtaatt atttggtctt cataaagttt ttgaataata gcaaaagcat ttttctcact
    50821 gattgtatca tcaaataact gatttatctg ctcaagtaat tgttttttat ctgaaatcct
    50881 tacttttgca attcgtatat aaccaccacc accacgtttg ctttctacta gataaccacg
    50941 ttggatggta aaacgggtat taatcacata gttgatttgt gaaggaacac agttaaagag
    51001 gtctgccatt tcaatccttc gaatctcgat catttcacta ttttccagaa ttttctttat
    51061 atatgattca attaaatccg aggtattctg atgtgccatc ttattcattc cctttgacta
    51121 atattgacct taattataac gaatttgata atagaaagaa agaagaacgc tttttgttaa
    51181 ataaatcctt tagaatcaac aaaaaaaaat acggaatata ctattccgta tcgacgcgcc
    51241 caagaggagt cgaaccccta accttttgat ccgtagtcaa acactctatc cagttgagct
    51301 atgggcgcat attcaattta aaaaaattat aaatcatttg aaaacaaaaa gcaagataaa
    51361 aaaaatcggg aagacaggat tcgaacctgc gaccccttgg tcccaaacca agtgctctac
    51421 caagctgagc tacttcccgt ttaaaaaata aaaaagac
//
LOCUS       DAIGSZ010000015        49494 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.015, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000015 DAIGSZ010000000
VERSION     DAIGSZ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.015"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(1..144)
                     /locus_tag="NOB31_000879"
                     /pseudo
     CDS             complement(1..144)
                     /locus_tag="NOB31_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(186..1312)
                     /locus_tag="NOB31_000880"
     CDS             complement(join(186..1084,1084..1312))
                     /locus_tag="NOB31_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI0973109.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(2375..2716)
                     /locus_tag="NOB31_000881"
     CDS             complement(2375..2716)
                     /locus_tag="NOB31_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI0973110.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(2716..2946)
                     /locus_tag="NOB31_000882"
     CDS             complement(2716..2946)
                     /locus_tag="NOB31_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0973111.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            3233..3571
                     /locus_tag="NOB31_000883"
     CDS             3233..3571
                     /locus_tag="NOB31_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973112.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(3776..4015)
                     /locus_tag="NOB31_000884"
     CDS             complement(3776..4015)
                     /locus_tag="NOB31_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HCI0973113.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTVISFARKIITQQMPELVMEKV"
     gene            complement(3991..4338)
                     /locus_tag="NOB31_000885"
     CDS             complement(3991..4338)
                     /locus_tag="NOB31_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HCI0973114.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(5070..5651)
                     /locus_tag="NOB31_000886"
     CDS             complement(5070..5651)
                     /locus_tag="NOB31_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0973115.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(5834..6460)
                     /locus_tag="NOB31_000887"
     CDS             complement(5834..6460)
                     /locus_tag="NOB31_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0973116.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(6482..7813)
                     /locus_tag="NOB31_000888"
     CDS             complement(6482..7813)
                     /locus_tag="NOB31_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HCI0973117.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(7968..8369)
                     /locus_tag="NOB31_000889"
     CDS             complement(7968..8369)
                     /locus_tag="NOB31_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCI0973118.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(8455..8661)
                     /locus_tag="NOB31_000890"
     CDS             complement(8455..8661)
                     /locus_tag="NOB31_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973119.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(8756..10258)
                     /locus_tag="NOB31_000891"
     CDS             complement(8756..10258)
                     /locus_tag="NOB31_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HCI0973120.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(10276..10731)
                     /gene="argR"
                     /locus_tag="NOB31_000892"
     CDS             complement(10276..10731)
                     /gene="argR"
                     /locus_tag="NOB31_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCI0973121.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(10829..11446)
                     /locus_tag="NOB31_000893"
     CDS             complement(10829..11446)
                     /locus_tag="NOB31_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HCI0973122.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            11667..13040
                     /locus_tag="NOB31_000894"
     CDS             11667..13040
                     /locus_tag="NOB31_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0973123.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            13115..14227
                     /locus_tag="NOB31_000895"
     CDS             13115..14227
                     /locus_tag="NOB31_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCI0973124.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(14299..15936)
                     /locus_tag="NOB31_000896"
     CDS             complement(14299..15936)
                     /locus_tag="NOB31_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HCI0973125.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(16104..16712)
                     /locus_tag="NOB31_000897"
     CDS             complement(16104..16712)
                     /locus_tag="NOB31_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0973126.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(17096..18247)
                     /gene="queG"
                     /locus_tag="NOB31_000898"
     CDS             complement(17096..18247)
                     /gene="queG"
                     /locus_tag="NOB31_000898"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HCI0973127.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(18266..19018)
                     /locus_tag="NOB31_000899"
     CDS             complement(18266..19018)
                     /locus_tag="NOB31_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973128.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(19159..20109)
                     /locus_tag="NOB31_000900"
     CDS             complement(19159..20109)
                     /locus_tag="NOB31_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCI0973129.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(20110..20949)
                     /locus_tag="NOB31_000901"
     CDS             complement(20110..20949)
                     /locus_tag="NOB31_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI0973130.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(20946..21692)
                     /locus_tag="NOB31_000902"
     CDS             complement(20946..21692)
                     /locus_tag="NOB31_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI0973131.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            21930..23300
                     /locus_tag="NOB31_000903"
                     /pseudo
     CDS             21930..23300
                     /locus_tag="NOB31_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            complement(23355..24251)
                     /locus_tag="NOB31_000904"
     CDS             complement(23355..24251)
                     /locus_tag="NOB31_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0973132.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(24365..24535)
                     /locus_tag="NOB31_000905"
     CDS             complement(24365..24535)
                     /locus_tag="NOB31_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973133.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(24532..25209)
                     /locus_tag="NOB31_000906"
     CDS             complement(24532..25209)
                     /locus_tag="NOB31_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCI0973134.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(25300..26205)
                     /locus_tag="NOB31_000907"
     CDS             complement(25300..26205)
                     /locus_tag="NOB31_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI0973135.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            26380..27804
                     /locus_tag="NOB31_000908"
     CDS             26380..27804
                     /locus_tag="NOB31_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0973136.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            27850..28881
                     /locus_tag="NOB31_000909"
     CDS             27850..28881
                     /locus_tag="NOB31_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCI0973137.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            28888..30075
                     /locus_tag="NOB31_000910"
     CDS             28888..30075
                     /locus_tag="NOB31_000910"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HCI0973138.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            30231..31613
                     /locus_tag="NOB31_000911"
     CDS             30231..31613
                     /locus_tag="NOB31_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCI0973139.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            31740..31970
                     /locus_tag="NOB31_000912"
     CDS             31740..31970
                     /locus_tag="NOB31_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973140.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(32170..32838)
                     /locus_tag="NOB31_000913"
     CDS             complement(32170..32838)
                     /locus_tag="NOB31_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HCI0973141.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(33027..33824)
                     /locus_tag="NOB31_000914"
                     /pseudo
     CDS             complement(33027..33824)
                     /locus_tag="NOB31_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(34105..35484)
                     /locus_tag="NOB31_000915"
     CDS             complement(34105..35484)
                     /locus_tag="NOB31_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0973142.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(35659..36828)
                     /locus_tag="NOB31_000916"
     CDS             complement(35659..36828)
                     /locus_tag="NOB31_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI0973143.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(36803..37954)
                     /locus_tag="NOB31_000917"
     CDS             complement(36803..37954)
                     /locus_tag="NOB31_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCI0973144.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(37914..39275)
                     /locus_tag="NOB31_000918"
     CDS             complement(37914..39275)
                     /locus_tag="NOB31_000918"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HCI0973145.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(39272..40273)
                     /locus_tag="NOB31_000919"
     CDS             complement(39272..40273)
                     /locus_tag="NOB31_000919"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HCI0973146.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(40289..40984)
                     /gene="dapD"
                     /locus_tag="NOB31_000920"
     CDS             complement(40289..40984)
                     /gene="dapD"
                     /locus_tag="NOB31_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HCI0973147.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(40990..41706)
                     /locus_tag="NOB31_000921"
     CDS             complement(40990..41706)
                     /locus_tag="NOB31_000921"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HCI0973148.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(41703..42584)
                     /locus_tag="NOB31_000922"
     CDS             complement(41703..42584)
                     /locus_tag="NOB31_000922"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HCI0973149.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(42587..43387)
                     /gene="dapF"
                     /locus_tag="NOB31_000923"
     CDS             complement(42587..43387)
                     /gene="dapF"
                     /locus_tag="NOB31_000923"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HCI0973150.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(43374..44633)
                     /gene="lysA"
                     /locus_tag="NOB31_000924"
     CDS             complement(43374..44633)
                     /gene="lysA"
                     /locus_tag="NOB31_000924"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HCI0973151.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(44848..45018)
                     /locus_tag="NOB31_000925"
     CDS             complement(44848..45018)
                     /locus_tag="NOB31_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973152.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            complement(45119..45682)
                     /gene="efp"
                     /locus_tag="NOB31_000926"
     CDS             complement(45119..45682)
                     /gene="efp"
                     /locus_tag="NOB31_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HCI0973153.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            46110..47027
                     /locus_tag="NOB31_000927"
     CDS             46110..47027
                     /locus_tag="NOB31_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HCI0973154.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            47040..48185
                     /locus_tag="NOB31_000928"
     CDS             47040..48185
                     /locus_tag="NOB31_000928"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HCI0973155.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            48356..48814
                     /locus_tag="NOB31_000929"
     CDS             48356..48814
                     /locus_tag="NOB31_000929"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HCI0973156.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            48973..49443
                     /locus_tag="NOB31_000930"
     CDS             48973..49443
                     /locus_tag="NOB31_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HCI0973157.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT        14017 a        10154 c         8838 g        16485 t
ORIGIN      
        1 ctccagataa gtgcgatact cagacgcatc attcagtaac aaccgaacgg ttgtcgtccc
       61 ccaacgaatg atcctagagg ggacgacaca aagacaatgg gaacactctt ctggcttgta
      121 cagaagagtt cctttgtaaa tcatggattt gagtcaatat cttggacaca ttttagtaga
      181 gacggttaag ccattttttc ttttgctaat tcttcaaatt cctgtggggt tagatagtga
      241 atcgagctat ggattcgatt tcggttataa aatccttcaa tgtagctaaa tagcgctcga
      301 tttgcttctt caaaatctga gtagctagtc gtgtagactt cttctttttt caatgaggca
      361 tggaaagatt cgattccagc attatcataa ggtgttcctt ttctactata agaatgcctt
      421 attttgttgg ttttaagcca ttgttccact tctcttgctg tgtattggct gcccaagtca
      481 gtgtgtagaa tcattccttc tggaatgtga taatgtattt ttgctttatt caatgtttga
      541 atgacacaat ccacagtcat tcgttttgaa aatgtataac taataatttt tttcgtgtgt
      601 aaatccatga ttgaagataa gtaacaccaa ccatttttct tagtaggaat gtacgtaatg
      661 tcagctgccc atttctcaca gatcgtttca gtagaaaagt cctgatttaa gagattctct
      721 tttgaaatga tcggtttatt agacctttga ggtctatatt ttttaactac aatcgacctt
      781 aaatttaatt gtttcattag cttttggaca tgtttaagag atactgaaat cccttctttt
      841 aataaaactt gatggatctt tgtggcacca tagcgttgtt tattcgtaaa aaaaattgtt
      901 gaaatcttct ttttcaactt attatttctg atttctgtag ctgtcaacgg tttattctta
      961 taaaaataat agacacttct agggatttct aataaccgac ataacaaaga aacagtgtaa
     1021 tccttacacc atttttcaat aaattgaaca agcgaattta ggttttccga gagaatatgg
     1081 ctgcggcttt ttttaagatt tcaagttcct catttaaacg agcattttct tttctcagtt
     1141 cagctacttc ttttccagtc agtcctgtgg actgatcagg taaatataaa ttcttccatt
     1201 tgtaaatcgt tgcttcagat aagccatatt ctttcgctaa ccctcgaaca gaacgtccag
     1261 tttgattcag ttcaacaatc atttgtttaa aattttcttc atatcgggtc ataaaaattc
     1321 atcctctcgt agataagttt aatttattct tgtctctacg aaaagctgtc taagatttga
     1381 tactaacacc acttggaact aatgtatcat taataaatgt tgaaaaattc agcaactcat
     1441 tactgtatga ttttagcagc ccaaccaaca tataccctat aaaagctaat aagatggtta
     1501 ggaatccttt agaattttta ctcattcata gacacttcct taaataactt ttattataga
     1561 aggtattgta aataataata ttgacaaaaa gtgactcaaa ataaaaaaaa ccttacatta
     1621 tactggaatg aactgtattg atagtgtacc taaaagctct actgacataa gatcgtgtaa
     1681 tcggtaaagt aattttatta attatacggg atgtaatcaa ttagagaata aactaatcat
     1741 aaaaggtact tttacattca taattgtcgc tttgagattc tactttggtt cactatctga
     1801 cccaattgca cattttcgat cattacaagt attggtgtcg ttagaacaac taaataaaaa
     1861 ctagcggtag atttttcaga atctatgcta atttctgtat ggatgttcca gtgatggcaa
     1921 atttctcttt tcattgtttt tcttgtcgca tgatatgcct ttttgtgtta ttcagttaaa
     1981 ctatagaaat tctttcctag acagatcttg atcccaaatt ttacgttttt gagcatcgat
     2041 atagtttaaa atgacattac tcatatctaa agagtttaga ttttttagga ctaaaactgt
     2101 cagttgttct ttttcttctt tctgttaaag tattgtcgcg acttttcgta tacgttaaga
     2161 tatgtcgtga aaaaacaagt tttgtgacac aaaaaaacga atgacttgag gaaatcacct
     2221 caatcattcg tttaaaatgc tatatattct ttagtttaag atacggaaat taatgccatc
     2281 gaccacacta gtagaatgaa cgacatttac ttggcctttt tttaatttcg ttatgtttag
     2341 catataaaaa tattatagag tttacttaca atgcttaaaa catatactgt ataatctgat
     2401 caattttagc catgtcttgc aatggtaagt tttctatttt tttgagtttt cgttccttaa
     2461 aatcaagaga ttttaattgt gtaataatta cttgtccttt tatatctagc tcttcaggta
     2521 atgagtaacg tgtcggtaaa ttctttatag tggaagtaat tggacatatg accgaaaaca
     2581 ttgttttacg gttaaattca taacgagaga cgactagtcc tggtcgtctt ttttgaattt
     2641 cttttcctac ggagggatca aaatcaatcc atacaatatc acctttttta ggaatataaa
     2701 ttctttcttc tgacactata aaatttctct cccttcagga gttaaatctt cccattcgtc
     2761 tttctcataa tactcggcct cttccccacc actaaatgga tcttcaattt ttggaactaa
     2821 cgtaattgtt ccatcatcag aatacacaac gatatattct tggttttctg aaggtttctt
     2881 tccgttatca gaaggtaaag ttaccactac agaacttcct tgtaatctag attttgtaac
     2941 aagcattatc atcactccct taataaaagt atactatata acactaagta acgcaaaatt
     3001 cccctttgta aactatctag aaaattgttt tgtttaaagt atatcttatt ggatataaat
     3061 agaaataaat tgtagccagt tcattttttc tttaactaaa aaaataatcc aagaaacatt
     3121 gaacctatgg atccaaaagc tacccaaata ctatagctaa ccccccgcta ccttcaattt
     3181 tgcagataaa acgctttggg agaaaatttc aaagacaaca ggccatccta tcatgcccga
     3241 ttataaacaa aaagctggct attccttttg ctctgacaaa tttcaattgg gaaagttcac
     3301 gaaactagca ggtgaagaag tttcaactgt tcggatcaaa gaatgcccgc ttcaaataga
     3361 aacattggtt caacgaattt caactagaca agactttgct attgtagaac gtgagatcgt
     3421 agctattttt gtagaagaag ggattttaca tgatccaact catatcaatg tggataaatg
     3481 gcaacctctt atctataaat tcagagaata tacaactgcc aaccagtcgt taactttgaa
     3541 ttttagattc caagaattca aagagtcata atgataaaca tcgttaggta taaataaaaa
     3601 agactcgcag cacgagtaaa aaacaaatag aagctataca ttagaaaggt cgactgtgac
     3661 cctatagatg cagtatatgc agcttatgag catttcttct gttctctttg tttttgggat
     3721 ctgtgctgaa gtctttttcg ttttttgccg ctctttcttt gaaaaatcga ttatgttata
     3781 ccttctccat tactaattca ggcatctgct gagtaatgat ttttcgcgca aaagaaataa
     3841 ctgttaccca aggttcgatt tgttcttcag tcaagacaag cggcattcgg tcatggattg
     3901 gtgcgactgt gcggttaggt tcagtagtca ttatgattga ttctgccatt ttttcatcct
     3961 gatggctacg ataaaaaccg ccaatataca ctattttttc cttatttgaa aacataaatt
     4021 tgtctttttc ttcattccac tcattgggaa aacacaacga ttttgcaaaa atggttgatg
     4081 aaaggtcttt ttttcttcta ctgtctctgc acgggcatta atcatcaatt gtcctttttt
     4141 aaatccggta aatccccact tcatgatttc cggagtgagg atgttttctt cctcttttct
     4201 taacgtcaca acaagatttg acggaaaaac ttctccagct gctaattctg ctgcctgctt
     4261 cggttgtttc gtctgggctt ctcgataata attctgaagg agctctgact ctagatcaaa
     4321 aaaataacga ccacacatcc taatccctcc caatcttttt ttctatcata cactgcaaca
     4381 agaagttcgc accaacaaaa cgctttcaat ttttgtagaa ctaaaaaagt tgtgacaagt
     4441 gacaaactct ccagtgaatg gtattctcct gccaactcct cggtcacaag tcacaatatt
     4501 caacaaacat gagaagctgc tttttgaaat tgttccttgt gactcggagt gaaacggcag
     4561 gcttacgacc tctgggtaaa cggtgttcaa aagccagttt ctcggtatta agccaaattt
     4621 atgcaaaaat gtagaaagct attttcacaa aatttttctt aatactcgaa actaagcgac
     4681 tttttcacaa cctcttcctt aaacggtgtt caaaagcttg catctgcggt aataagccca
     4741 accaaacgaa aaatatgagc agctattttt atttggctgt tcttattact tgatgcaggg
     4801 cagctttttc acaacctctc cactaaacgg tgttcaatca gctaaccttc ggtattagct
     4861 caaaaaacgg caaaatatga ggaactattt tgccgtttgt ttctctaata ctcaggtcaa
     4921 agcgctgatt tcacaacctc taatacacgg tgttccagaa gtagcttctt cgaaaaataa
     4981 gccgaaattt cacaaaaatt tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag
     5041 ctgaccactt ctgtcacaac ctctaattat taaagaacct tttgcgaagt taacaatctt
     5101 tctttgatca attgaaaatt ctgcctaagt agtgatagat cctgtgtgac tttcaacaat
     5161 aagatacttc cctggatttc agcaatcaac gctttggctt gacggtctgc ttcttcatcg
     5221 gacagttttt cttcagaaag tgccaggata ttttgtttcg tatacttgac ccattgattg
     5281 actaattcta gtagcaacag acggtattct tcatccactg tactcaactc aataatcaaa
     5341 ttacctacag gacagccatg ataagtgatc tgtgtctcat gatcagcgaa aatccagtcc
     5401 aacatttctt ctaatgcttc ttctggctgt tttccagcat ttaagatgtc ttcgaacaat
     5461 tctgtctgcc atacgtccat atgcgcatgg atcaccgcta gacaaacttc tttttttgaa
     5521 gaaaagtaat aataaaattg accttttcct gtatcagaag ctgctagaat atctcggatt
     5581 gacgtttcat gatagccttt tttataaata agatctttgg tcgcttccaa gatcttttcc
     5641 tttgttttca atgatattct cctttttcat ttctcatagt cctatattat acagtaaatt
     5701 catcattttt tcttcttaat cgtttaaaaa agactgtgcc aaattatctg acacagccct
     5761 cactataaaa ctgttctcat atagctagat gttcattgat tcaagaactg cgaggacaaa
     5821 agcaattcct atcttatgat agttgctcta atacttcctc tgttgtcatc acttgatctg
     5881 caataaagcc aaagttcgtc aacgctgcat ccattgcttc ttggccagga gcaccaattg
     5941 catctgtcgc taccacaaca ttgaatccac tctctaccaa ttcacgcata tgggaatcgc
     6001 tacacaagtt tccgttcatt ccaccaagaa ttactgtgtc gattccattt tttctcaatt
     6061 ggagcgccaa atcattgctt tctggtccaa agattttatg aggagagctg atgatcgtat
     6121 tttcatccaa ataaggtttc aattcttcga taaaatcggc tcctgaacct tcttccactg
     6181 attcatattg actttttcta gcaaacatct gctgctcaag catcatatgt tctcctgcac
     6241 cgccaaattg ccatttatgg tcatgtgggt aaaaataatg aggagaaata aagagtttgt
     6301 atcctttttc ttttgcttgt tttaccattt caatcatatt ttcgatcgta ttgtattttt
     6361 ctaagatatc ttttgtcaaa ccaaagccac cgcctgctgg tttcaagaac tcgacttgcg
     6421 ggtcagtgag aactactgct gtatttttat tattgaacat ggtggattct ccattcgtta
     6481 tttattttaa tacatcattt agagcttcac tcattgtcgg atgagaatag atttgatctc
     6541 tcaataacgt ataaggaagt tttccattca tagctagcga aatcaagttg atgacttcat
     6601 gagaatcttc cgcatagata cttgccccta gaatcaagtc agtttcaggg tcgactaaaa
     6661 ctttgaatac acctttagga tcttctaata cttgtgcttt agggacaccg cttgtcatat
     6721 acttgaataa tttgtaattg acgccttgtg ctttggcttg tttttctgtt aaacctacat
     6781 tggataaagt cggagtgata aatacactgt aaggcacagc tttccggtta ttcgttgttc
     6841 gtttattctc gcccttcaac tgatccataa tgattcgata atcatctaga gagatataag
     6901 tgaactgcaa tccgcctttg acgtctccaa tcgcccaaat gttgtctgca tctgtacgaa
     6961 ggtattcatc cacagcgatt gctccgcgat ctgttagttt aacatctgta ttttctaatc
     7021 caagtgatgc tgtacttggt tttcttccag ttgcagccaa aacttttgac gcttggattg
     7081 ttacttcttg gccatcttct gtaaaggtga cggcagctgt tgattcttgg tctgctactt
     7141 gatctacaga tacacctaga tggaattcga ttcccgcatt tgtcatgtct tctaaaatca
     7201 tttgcgcgat atcttcatct tcacgtggaa gaaattcaga atgggcatca agaacgacaa
     7261 ctttagatcc gtattcattg aacattgatg caaattccaa gccaatatat ccagccccga
     7321 tgatcactaa tttttccggt aattgttcct gatccatcgc ttgcgtagaa tcaatcaagt
     7381 agcgacttgt attcaatcct ttgattggta aaatgattgg ttcagaacca gtattgatga
     7441 aaatccgttc gccttcaaca atcacttttt caccattatt cgtcacttcg atttgatggt
     7501 tagaaagaaa acgtgctgta ccgtccatca ctgtcccagt tgcctcatcg ctgatcatat
     7561 gataattttt ggcgcgaagc atgcccgtca atttttcttt ccgagcaaca gcctctgtaa
     7621 agtcgattcc tctttctcca ttgaaaatca atgatttaga aggaatacag ccgatgttga
     7681 tacatgttcc gccatacata cgtgttgact tttcaacgac taaaaccgat tcaccttttg
     7741 aagctaacgc cttcgctaaa gtcttaccgc cctttccaaa accgatcaca atattttgat
     7801 atttttccat catttttccc tcgcttcttt tttacctacc gattggtaca aaaatatgat
     7861 aaccgataat tgtctattct ccaaatcatc tgctttattt gtcaaaaaaa accagacaaa
     7921 aagcggtcct ttcacgtttt tagtctggtt cgatttcctt tattcttcta aacaatcgtt
     7981 acttctacat cgatatttcc tctagttgct ttggagtaag ggcagaattc atgcgcatct
     8041 tctgcaattt tttgggcttc ttcttcgctg atgccatcga tatgcacttc taatactaca
     8101 ccgatctgat agccgccatc atctaaatta taaagagaga cacgtgcttt tactgtggac
     8161 tctgctgtca ttcctgcttc tttgatcata tgttgtaccg ccccattgaa acaagaagca
     8221 taacctgctg caaataattg ttctggattt gttccttctg catggattcc tggaggagtg
     8281 attttcatat gcatcgagcc atttggtgcc tcgacttctc cattgcgccc gccatggttg
     8341 atcattgctg tttcgtatgc ttttttcatt gtactgctcc tttcgattga ccatttgcta
     8401 cttggctata attatagtgt atgacaagta aggcgctttc tacaaaaatt ctgcttattc
     8461 gaataccaga atgccgtctt ctactatttt tccaaaaaac aaaaaaatac tactcgtgaa
     8521 caacagcgtc atatttgttc caaaataaat agcaatcttt tctacataat cttttatatg
     8581 attgatttta agatacatat ataccagaaa gttgacccca taaaccaata ctgttaaaaa
     8641 aataaccata ttcgttacca ttttttcctc cttttgctgg tctccctacc agcactcgat
     8701 ttaaccatac cacttttttt gccgtccaag caactagcct ttcaaaaaga ctggtttatt
     8761 ctgctgttaa tgattcaaga tcagaaaaat gtccgaataa ttttgctaat tttactaacg
     8821 ccaacttgtt ctttccgaat tcatcatttt ctatctgtaa tactagtaac ggctcatgta
     8881 agcttaaacg gatcaaaaac cagccgtttc cgtatggctc ttctagatca tatcgaatac
     8941 cttcttcatt ttccgggtcg aagttcatcc ctttttcttc ttccaacagt cgcttcattt
     9001 cttctaatat cttgtttcct tgttcgcgtg gttcatcgct gaacaatttt aatcggattt
     9061 cttgtacttc tacgggctgt ttcaactctt tgatttgttc atctaatgtg ataccttttc
     9121 tttttaattc tggcaaaagc atcaggatct ttgcgatgac atatgcacca tcatccagaa
     9181 aatagttttc cttgaatgca gcgtgtccgc ttgtttcgat ggctagctgt gtatctttcc
     9241 caagacggtt aagttctaat gctttattga ttacatttcg atagccggaa atataacgaa
     9301 cttggatgcc tcctttttct tcaatgaatc tttgtagatg agaagaagta ggggaattcg
     9361 tcacgattct tgttcctgga tgctctttta atacgattgt acttaatact gcgatcaaat
     9421 tatttcgatt gatcactgtt ccagaagcac tgacaactgc agaacgatcc acatctgtat
     9481 cgaaaatgat cccaagatct gcttcatttg ctaaaacagc ctgcttgata ctttccatcg
     9541 cttctttatt atcaggattt gggatatgat taggaaatcg gccatctggt tccaaaaatt
     9601 gggaacctgt tgaatccgca cctaagctat tcaatacttt ttcagcaaag aatccaccag
     9661 caccatttcc ggcatcaaca atgattttcc aaccatttag tggtttgctt tctagtgttc
     9721 caatcccctt tttaattttt gtgactaaat cttgcgcata aggtgtcaaa aggtctgctt
     9781 tttctacgct tccagtttgt tcgcttttta ttttttgctg ctgtgatagg ataaaagcaa
     9841 tatcttcttt ttctgctcct ccttctgagg taaagaattt tattccatta taataatagg
     9901 gaagatggct agcagtcagc ataaccgcag catcgcacga gaactgttca aattgagtgg
     9961 acataaacat agcaggcgta gtagctaatt cgaaatcgat gacatgtatc ccttgttctt
    10021 tcagactttg gatcaacgcc tctttcagtg ctggtccgct tatcctactg tcatgaccaa
    10081 tcccaatcgt ccatttttta tttggatcgg ttgatttctt ctttttcttt atccagtttg
    10141 ctagtcccca gccgatcttt tttaccatgt ctgtcgtcaa gtttacttca tatccttcaa
    10201 ctggtaatgc gattcctcga atatccgatc cattttgcag cgctttcata tctttcatat
    10261 aaaagtcctc ctcatttatt ccctcatttt ttccagcttt tctgcaaatc gctgtgcttc
    10321 ttcttctgag cggcaaataa taatgaatgt atctacaccg gccatcgttc cgacaacttc
    10381 agggtaagcc acttcatcta gccaattcgt taccacatcg gcaccatttc gttcagtcaa
    10441 tacgataacc atgaactgaa cagactggat acgcaaaacc tcgcgtctaa ttgctgtacg
    10501 caaacgttct tcatttaaag aaacagatgg ctggttaaat aatgtatagc gtactatttt
    10561 gttttcattt tgacttttta ctaacttcat ttctcgaatg tctcgagaaa tcgttgcttg
    10621 agtcacatcg gcgcctgctt catgcagccg cgcaagcagc tcttcctgtg tcccaatagg
    10681 ttgttctgta atgatctggc ggatcagtgc ttgtcgctgt ttctttttca tattagacac
    10741 ctctcaatgt tgattatagc aaaagataag taatatttct tcatattttg gtatttttta
    10801 cttttatttt ttgttttcat tcaggttgct aacctttttc tattttaaca cgcaaaatcg
    10861 tcttcatttt ttcaggtgct gattttcttg gatcgctgat gtaaatctct ttgtgttctt
    10921 tagaagctct ttcatagcct tcttttgcga tgaatgcttc taatttctca aacgttgctg
    10981 gttcttcggc atagggcccg acgtgtaaga tttgggcaca aagaccttct tccatctttt
    11041 tgaatactac ttgttctttc aagtcttccg gaagtttgct agaacgctga atggcttctt
    11101 gtgctatcgc ttctgtaaca aagtcaggct gtcggatcat caattgataa gaaaaatgtt
    11161 cttttttcat cactggttca tgcaaatact tttcttgcag tccccattgt ccttccagtg
    11221 gatagacagt atacatctga taatcaggaa tcagccaatt ttttttaggc gacatgcgta
    11281 ttgcatagct gactgcatat agacaggcta ctcttcgttt aaagtcttcc tgattcgggt
    11341 cgccgatccc tctgatgcta aagaatgatt ttttaggaac ctctagtatt tgcgggcttt
    11401 ttttcatact atagctcttg tctttacgcc attcaatttt ttccattttt cttcctccgc
    11461 gaaattccat ttagttattt attatcatac ctctttttga gtgacttggc taatcgtgtt
    11521 gacactattt ttcagtttgt gctagaataa gtgaagtaaa taaatcgtac agataacacg
    11581 tttcggcgtg tcgagagaga ggcggtttct atttttataa tagaaatcac tctctttttt
    11641 tacgaaattt tttagaggtg atgtaaatga caaaacaaaa acagctgctt ttagtacctg
    11701 cagtaattgc aacagggatg atgtcttttg cgggcgtatt gatcgagacg gccatgaatg
    11761 taactttccc aactcttatc agacagtttg atttaacgac tgcacaagtc caatgggtaa
    11821 caacgattta tcttttgatg atttcgatca ttgttccgct gtctacttat ttgaatcgca
    11881 attttagtct caaaaaactc tttttagctt caaatctgct tttcttggca ggtataatga
    11941 tcgatttctt ctctcctacc ttcatggtcc tattgtttgg tcgattgctc caaggtgcag
    12001 cgacaggtat cgctcttccg ttgatgttcc atattatctt gacatttgcc cccctcaatc
    12061 gacgaggcgc gatgatgggt gtcggtactt tgacaacggc cattgctcca gcaattggcc
    12121 ccacttatgg aggcattatg acttcacatt ttacatggaa tcatatcttc ctgtttcttg
    12181 tgcccgtttt gtttctttct ttgattatcg gctggtttgc tattcccgag atggcagtac
    12241 aaaaaagtgg ttatttggat tggataagcg ttttaggaat ttgtcttttg tttagtggaa
    12301 gtctaacatt tttgagtacg ttgggaacag tttccagctg gattgcttta atcatcggcg
    12361 gtattggctg gttccttttt tactatcgaa gtaaaaaagt ggagcatcca ctgatccgac
    12421 tgtctattct ttcaaataaa acattccgct tgtttttgat tggcttctta gtttatcagt
    12481 ttttattact tggtgtatct tttgtcttgc cgaatttcct tcagatcgtt caaggaagta
    12541 gtccttttgt cgctggatta gcgatgcttc ccggcgcagc ggttggtgct ttgctttctc
    12601 ctttttccgg gaaaatgctg gatcaatatg gtccgaagaa gccaattttt gctgggctga
    12661 ttctttcttt gattggttgg ctagcattat tcctactcat aggacacgct tcagtgggtg
    12721 tattgattgc ttgtcatgtg ttttatatga tcggtatcgg attatcttac agcaatatga
    12781 tgaccaccgg aatgaatgca ctgaatgaag aactacaagg agacgggaac gcaatgttca
    12841 ataccttgca gcagttttct ggcgctgtgg ctacttcatt agtagcggtc attatcaatt
    12901 acgtccagca tcatacttcc cataactatg aagtgtctac tacattagga tcaaaagcag
    12961 cattaggcgt cttgttgctg ttgcttctcg taagctttgc tcgattcgcc tattatctgt
    13021 tctttgctaa aaaagcgtag attccatata cggcaggtgt tgcatctgcc gtttttttgt
    13081 gtgaaaatgg ttgtttgtaa aaggaggctt ttttatggaa aaaattgcca ttatcggtgg
    13141 cgggatcatt ggtatgaccc tagccagtta cttagataca tcaaaattca atgttgcttt
    13201 atttgatgaa gggacaggac aggcaactaa agctagcgct gggattatct ccccttggtt
    13261 gtcgaaacgc agaaacaaac aatggtatcg tctggctaaa gacggcgctg cttttttccc
    13321 taaacttata aaagatttcc aacttgatca aacgatttac gcacaatcag ggacactttt
    13381 gcttcgacct gaaaaagatt tagctgaatt ggctgttctt gccgagaaac gaaaagaaga
    13441 agcgccagaa attggaaaca tcgaatggct ttcacctgaa cagacatctc aagcacttcc
    13501 gttattgaaa ccagcagttt cactgcgtat cagtggtggt ggtcgtctgg atggaaaagc
    13561 atatttagaa catcttggtc agcgtttagc acaaaaacaa atggagcaga tccaggcaaa
    13621 agtcactttg cataagaaga gcgattcttg gctcatcaag ggaccgtttg gagaatacac
    13681 agctgatcgt gtaattttga cacctggccc ggcacttaag cctttattac aagaattagg
    13741 ctatgctgca gatatacgtc cgcaaaaagg gcagctctta gcatttcaga catcttataa
    13801 gatgagtcaa gactggcctg ttgctatgct tgacggagaa gctgatttca ttcctttcat
    13861 ggatggaaag atccttttag gtgctaccca tgaaaacgat caaggctggg atttggctcc
    13921 tactagcgaa gcttataagg gattgactaa gagtacagaa cagttcttga ctgatccaga
    13981 tcagataaaa aactggccat acgagttccg tgtaggtacc cgtgcttata cgtcagattt
    14041 ttccccattt ttcggcgtac tgccagatga tccaagctta ctggctgcta gcggtctagg
    14101 ctcttctggc ttgaccacag gtccttatat cggctatcta ttagccaact tcttaaatac
    14161 tggtcattgg cctacggaag attatcaaaa ggacatctcc acctatatta cgaaaaatcc
    14221 atcatagaaa aacagctttt tcaagtaagg atcccgagcg atattgcgca tggattactt
    14281 cttgaaaaag ctgttatttt agttcaattt ctgaatcaaa ttctccaaac tttcttttgc
    14341 ttcatctggc aagagatctt ttcctatctg agcttcaatg aatcgtaaac gaatatcaag
    14401 tcgttgtttc accagatttt tataggacgt atcctcaaaa gaaacaggaa aatctggtat
    14461 aggtaaatag tggatgtctt caaatggacc aaacgacttg aattctgccg tttgttgcac
    14521 gattctttca acgattgaca atgtcgtttc aggtttgatt tttttatcat cgaaatatcc
    14581 agtattcagg acatagcagg ctgtttgctg tttcaaaaac aactctcgaa aagcttgata
    14641 gtcttcccta agaggataga cacggaaagg attagcaaat ggttcaatga ctagctcatc
    14701 tagctgtctt tttgtagtga tattttccgc gtctgatcgt tttgttgcta atgttgcacc
    14761 aaaagacgct gctaaaactg ggtcattgat cttgataatt ggcggaagcg aatcatcttt
    14821 catgatccaa aaaacagcat cgatcttttc gctaagatga tcgactcggt cgggtgtcgc
    14881 ataacgtgat ttgactgtcc gcccatttcc gtttcgtata tctcctgtta ctaggacttt
    14941 ttctccttta cttgtacatg tcacgcccac attctgacaa gtaaggaaag aagaaatggc
    15001 cggatcatca gacggatagt cttgtgtttt atcaaagtaa gaaggttcca aggcagtagc
    15061 aaaaccattt tttcgagaaa taacgaaagc atcgtcatgc aagatcgaaa cagagtgacc
    15121 ttccgtatgt tttgctaagg taatcgttga ttttccagaa ccggacaacc caaatacagc
    15181 catcgtatag gtctggtcat tactagcata ttgtttcatc ccaccgtggc aggcaataaa
    15241 gccattgcga tttcccaatg cccaagcaag cgtcaaagtc gcttttttta attctccaaa
    15301 gtaacgtaat cctagcacag ccgctgtatt atggagagca tcaaacaaaa tgagtccatt
    15361 tggaaatgtt tcatgtgtcc attcgggatc acaaaagata taaagatctc cctcatcaaa
    15421 ggaaacagac ttttgataag tctctaagat cttcgaattc gctggctgaa aattcagcaa
    15481 ataagaatac aaattgttct caaatccttc tggaatcagc aaatgacttt gcacagaaaa
    15541 ttcttcagat aggccaacga ttacttttgt atggtaaaac tggcgcttgc gactttgata
    15601 cacagcttct cttaaaattt tctcgtattt gctttgttcc ttgtctaagt cctcaaagat
    15661 ccgccgagca cttgctgttc ttcccacaat gcttccatca ttgaatacta gtgtcctaac
    15721 atcagctggt aaatctagtt cttcagcatg tgagattgtt aaatctgtga tgatcgttcc
    15781 tggactccct tttgctagtt gataagctgt cttcctatca aaaacttcat gaacattatt
    15841 accgtaaaat gtcgtttcta caatcgatcg aatactggat aacagtggat ttccacttgt
    15901 gatttcgttt aattcgagac tctcttttgt actcatggct cctcctcatt ccctaaacaa
    15961 aaaaacgttt tctttattat acattattcg agtttttatt tgtactgctg cgctgtggga
    16021 agcaaacgag ttatttttca cacaaaaaaa ccgagaactt gaataaacaa gtttctcggt
    16081 ttcatcattt tccttttatc ggcttagtac cagccgtttg ctaaccagaa tgttttagca
    16141 gcatcccatg aaccataacg agatgttaca tattgttctg ctacacgttc ttgattggca
    16201 gctgaatagt cgccgtttaa gtatgaagca tctaattgat aacggccgat gtaacgtccg
    16261 ttagtagctg tgtatgaacc gcctgattct ttttgtgcga tccattcttt tgcagagctt
    16321 gaagttggcg ctgttgcagc agctggggca gcaggagcta cttcaactgt ttcaacaggt
    16381 gcaacgtatg tatgttcttg cgttgctgtt tcagttgtag atgctgtatt ttctgttgtt
    16441 ttgttttctg ttgttgctga agaatcattt gaagttggga ttgttaattg ttcaccaaca
    16501 taaatgcggt tgatgtttgc gatcgaattt ttttcagcaa ttgcatcgat cattgagttg
    16561 tctcctgcaa atttttgtga gatcttagat aatgaatcac ctgattttac tgtataaact
    16621 tcatcagcgt gagcatttgt agttcctaca aacattgcag tagcaccagc agcaaaagtt
    16681 gtacctaaaa caattttctt aaatgaattc atattaaact cctttttttc tccgtttttt
    16741 attctttcga cgctattaac tttatcattt agaaatattt cataggtaaa agaaacatga
    16801 catttaatga caaaataacg aattatttaa tatttgtaac atttaaacaa atattttttt
    16861 gatacaaaac cataaaagcc ttgttgtata agcaaagtaa tcgtttttct atgttttttt
    16921 atttttgaat gaaaaacgca gattctgtaa cattcactgc aataatccat aaaaaaaagc
    16981 aaaaaaattt ttgattttta tcaaattctc ttaaaaaaat gtaaaaaata caaaaaaacc
    17041 agtaattgtt acaacaatta ctggacaaaa actttgaata atgttaacta tttttttatt
    17101 ttaactttct ccgcaataat ttctgggcat gttccaattc gtttataacg acttcttctg
    17161 tttctttagc taatatttca tctaatacat caagccattt ttccggttct tttgttccta
    17221 gacgtccaat agcccaagct gctgttcctc tgatgacagg gcggacatct gttaaacatt
    17281 ctgaaatctc aggcaatgcc gttcgatcac ctagattagc taaagcaatc aatgcgtttc
    17341 tctgcaaagg tttcttccca cgccatgaac cagctaaatg cccaaattgc tgtttgaagt
    17401 ctttattaga catcgaaagc attggcttta attttggata tatttcgtct acttttggtt
    17461 ccatctcttc atgaaaatga aaatcttttc cttgattgta agggcagact aactggcaga
    17521 tatcacatcc ataaatgaca tttcgcattt ttttacgata ttcttccggc atcatccctt
    17581 ttgtctgagt ttgataagac aaacatcgct gggcattcat tcttccgtca ccaagcaatg
    17641 cttttgtcgg acaagcagtc acgcagcgca tacagtcacc gcaaccaaat tctcctggtt
    17701 tatcaggctc aaatacaata ttagtaacga tctcaccaag atagacaaat gaaccgaact
    17761 cttcagtgat caacaatccg tttcgtccaa taaatcctaa accagctcgc tgtgctacag
    17821 cgacatcgat cagttctcca gtatctactt gcggagctag acgccattcc tcttcttttt
    17881 gccatttttc tgctcttgtt tggatgaatt cgatcaatcg gttcaaacgg tctctgagta
    17941 tatcatggta atcgatcccc caagaagcac gagcaaactg cccgcgtttt tcatccctag
    18001 gcacttcttc atggatccta gtaggatacg caagtgcaat ggaaatgatc gatttcggct
    18061 gatcaaatgt catttctgga taaagacgct catcgatatt tggatgttca aagccagaag
    18121 tatggccagc tgctttttgt tcttccaacg attcttttaa tgaatcaaaa ggttccgccg
    18181 tggtgaaccc gattttgtca attcctaatc gtttgctttc ttgtatgatt tcttctttta
    18241 atgtcatggt cttcctcgct tgctgttaac ggctgtataa cccataatat agtttttctt
    18301 ttttcagctg gacaaactgg atctgctgat cggcaatctt cttttcttcc atccattttt
    18361 ttcttgcagc aaatacttcc caataatttg ttgaaattaa ttttcttttg ttatctaatg
    18421 cattaaaaaa attcaatgaa actggttttg tacttaacag ttcatggagc cttacctctt
    18481 cccatggcga aaactcagac agatcgcggg aatacaatac ttcttcatag agattttttt
    18541 gctgtgtgta cgtgaatgtt tgcgggattt tcccaggcct agcaatttct actagacgat
    18601 tataaaacat attcattaat ttgctgttgg caataaattg acttttataa taggccgact
    18661 ggatcttttt gattactcct tctgctttga tgactgaaaa taatgcaggc catgctttga
    18721 cggttatttc gtcgttttgt ttaactaata cgccaggtgt gaagccgact ggagaaagga
    18781 acacaaaata accgataccg gtattttcat ctaaaggctg aaattcatca aacaaccatt
    18841 tgcctatgta cagctcttca tctggttctg ttgtctcatt ttgatttgct atgaataatt
    18901 tagctaattc tgcttcaaga aattgaaggt cttgatcctt gtcggtattt tcctgctggc
    18961 tgatcaatcg aaagacttct tctttaatcg tatatttatc tttacgtgta aaattcatag
    19021 ccacaccttc cttccttact ctaactataa cggaatttct tcaaaaaagg tatctgtacg
    19081 acgaaaaaca gcataatttt ttttcatatc tcttataaaa aatgcaaggt ctgctcctca
    19141 agctagacct tgcacttttc agctttcttt tgtttgtgac aaaccttcat ggatcgtttc
    19201 aatattccat ttcatcatct gatagtaaga atctccttgt tctccttctt ttgctatgga
    19261 atcagtgaac agtttatcat agattttcaa acccgtttct tttgctaccc gttccatgct
    19321 tcttgagtct acactggttt ccacgaataa aaccggtact tcttttgctc ttatctgatc
    19381 aatgatcgct ttcatttgat caggcgtacc ttgactttct gtattgatct cccatatata
    19441 agctgctggc aaatcatatg ctcgtgaaaa atacttgaat gccccttcac ttgttactaa
    19501 taattttttg ttctcttcga tagaagcaaa actttccttc gcttgtgtat ctaattcttt
    19561 tagtttttcc acatatgctt ctgcattttt tttatagagt gtcgcatttt ctgcatcttt
    19621 ttcagagaat atacgtgcga tttcctccac atattttatt ccgttagata ggtctagcca
    19681 agcatgggga tctgcttttg tatgttcttc accgctagtt aaataaagag gttctacatt
    19741 tttgctaact gcaaaataat cttttccttc ttctttttta gccgtttcca tcaagttatc
    19801 gaaccagctg ttacctgttt caagattcaa accgttgtat aaaataacat ctgcatcgct
    19861 tgcctttttg atgtcttctg gtagtacttc atattcatgc ggatctgttc cgactggtac
    19921 gatactgtgg atatctattt gatctgttcc gacctctttt gccatgtccg ccaagatcga
    19981 attggtagcc acgactgaca acttttcttt acttccttca tccgcttggt cagaagcctg
    20041 ctttccgcaa ccggctaata ccaagaaact aactgccaag attaaaaaga gtgatttttt
    20101 tgttttcatc tatctgcttc ctttctgaaa taaaattcct tttgttggag aaaataaaaa
    20161 agcaaggata aaaaatgcgg tacatgctaa cacgatcgta gctcctgatg gccaattgta
    20221 actataactg aaaaacacac cgacaactgc acttagcata ccgattcctg cagctgtaat
    20281 gatcattttc agtaaatggt tcgttagcaa gtaagccgtg gcggctggtg tgatcaacat
    20341 ggcaatcacc aagattgttc ctactgtctg taaactgact acagccacta atgtcaaaaa
    20401 gaacatcaaa agataatgga tcagcgatgt gttcagccca taagcttttg ccattgtcgg
    20461 atcgaatgat gtgatcttca attctttata aaagaaaaag acaaatatca agacgattcc
    20521 actaacgagt gctgtcagca acaaatcgct ttccctaaca gctaagacat tcccaaataa
    20581 aatatgatac aaatctgtcg cactctgggc atatgaaatc aagataatcc ctaatgcaaa
    20641 aaaggagcta aagacaattc caatcgctgt atcatttttc aatcggctcc gctgagtcac
    20701 gaaaccaatc actgctgctg ttagcatccc aaaagcagtg gctccaaaga tgtaactaaa
    20761 accaaacata taagaaatgg ctacacctgg aagaactgcg tgagagatag cgtctcccat
    20821 caaagacatc cctcgtaaaa taataaaaga accgatgact ccagaagcaa gtcctacaag
    20881 catggaagtg accaaagcgt attgcaggaa ttgataattc attaatccat caataaagga
    20941 ttggatcatt ttttctctcc tccttttact aaatgtctga tgatctcacc ataggccaat
    21001 tgaaggttct tcgatgtaaa gacttcttgt actggaccgg aagcgatcag ctgtttattt
    21061 aaaagaataa cctcatcgaa atattcttct actttatgaa gatcatgatg gacgatcaaa
    21121 atcgtttttc ctgaattctt caattcctgc aagatgtcaa agatctttcg ttcacttaac
    21181 gcatcaatcc ctacgaatgg ttcatctaaa aagatccatt ctgctccttg ggctagagct
    21241 cttgcaataa aaactctctg aagctgtcca cccgatagtt cgctgatctg tcttttggca
    21301 tattcttcca tccctacttt tttcaaagct tgtcttgcac gttctttttc ttttttccca
    21361 ggtctttgtc caattcgtaa agatggatat gttcctaaaa gtacaacgcc taatacatca
    21421 attggaaagg aaagatccaa ttcacttcgc tgttccacgt aggctatttt tttacggact
    21481 gagtttaccg actgtccaga aaaggtgact ttaccagtag tagctggtat caactctagc
    21541 aaagatttca taaatgttga ttttcctgca ccgtttggtc cgataatacc ggtaattttt
    21601 tgtggattta tcgtcaagtt gatagttttc aaaacagttt tcccttgata agcggctgaa
    21661 aggtcttgaa ttacaatggc cgtacgttcc aaatcttaca ctccttttta ggtttaccta
    21721 actttttatt taaatatagt ttaactaaaa tggaaagcat tttcaagtag aatgatgaaa
    21781 aagttttttt cgaattttcc tcgcatttta tgaaaatttt ctgtagaatc acatcaagag
    21841 ttcaataagg ctaacctaat aatgaaaaac atgtgttgaa acgtttgatt attttttctt
    21901 gttgactcaa caacgaaagg agtttttgta tggaagaaga aaagttaact cgaagtctta
    21961 gtgcccgtca tatccaaatg atcgcactag gtggaacgat cggtgtcggt ctgtttatgg
    22021 gtgcctcctc aaccatacgt tggacagggc cctcagtgat gggagcctat gcgattgcag
    22081 gattcttttt gtatttgatt atgcgtgctt taggcgaaat gctttacgtt gatccttcga
    22141 ctggttcttt tgcaaattac gcgagcgagt acatccatcc tgtggctggc tacttgaccg
    22201 cttggagtaa tatttttcaa tatattgtcg taggaataag tgaagtgatt gctgtaggat
    22261 cttatatgaa ttattggtgg cctgatttgc cggcaattat tcccggaatc attgtcgtct
    22321 tgtttcttat gctggcaaat cttatttctg tcaaggcgtt tggcgaatta taattttggt
    22381 tttcgatcat caaagtcata acgatcattt tgatgatcat tgcaggtctt ggggtaatct
    22441 tatttggatt tggtaatcat ggtcaggcag tagggatttc aaatctttgg aaaaatggtg
    22501 gattcttcac tggaggcgtc aaaggatttt tctttgcatt atcgatcgtt gttgcttcct
    22561 atcaaggaat cgaactgatc ggaatgactg ctggtgaagc agagaatcct aaaaagacga
    22621 tcattgaagc tgtccagtcc actatcggtc gaatcttgat tttttatatt ggtgctattt
    22681 ttatcattgt gagtatctat ccgtggaatc aattgagtga gattggttca ccttttgtac
    22741 aaactttttc taaagtcggc attacatttg ctgcaggact gattaatttt gtcgtgatta
    22801 cagcggcatt atcaggttgc aattcaggga ttttcagcgc aagtcgtatg gtctatacac
    22861 ttgccataaa tggaaagatg tctaaaaaat ttctgaaact atctcgtcac ggtgcgcctt
    22921 tttatcctgt cgtagcaatc tcaggtggaa tcttaattgg tctgatctta aattatcttc
    22981 taccaatgtt catcaaccag tcagaaaata ttttcgtttt cgtatacagc tcaagtattt
    23041 tgcctggtat ggttccttgg gtagtgattt tgatcagcga gattcgcttc aaaaagaagc
    23101 acgcagataa aatgcatgat catcctttta aaatgccact atctccttat acgaattatg
    23161 tgacacttgc ttttttagct atcgtattga ttttcatgtt tatcaatcct gaaacgagaa
    23221 tctcattgat tattggactc gttttcttgc tttacatgac gatccattac tttgtacgcg
    23281 aaaaaagaac cggaaaataa aaaaagaacg aagcttcacc ttagtggaag cttcgttctt
    23341 ttttattgct tttatcaatt caattttagc gtctcaccgg gagtcaggaa ataattctcc
    23401 atgctcatcc cattcagcga caagatcgtt tctactggta cgccagttcg ttcggctatt
    23461 tgatttggac cttctccttc caaaactacg gttgtcgcag cctgtgaagt cgcgctgttg
    23521 gtattagttt cagaggaatc tgttgtgtct tgtgttgttc gagcttgcat ttcagaagct
    23581 tctaccgact ctgctgtctc agaatcagaa gatgttgtgt cttgtgtgct tgttgactct
    23641 gcttgaagag aggcgctagt ctgcaaataa atatcggaaa tcttagcgac atgattcgta
    23701 taattagccg ataattgatt gatcaaagta tctaagtcta caccgtcttt attttctgct
    23761 gcctgatacg ctgcacgtaa ttttctgatc ccttcgtcgg agattgcttg aagctcacgt
    23821 gctttttggt tagcaactgc tgataaacca gctattccct cttgatttcc ctgaatttct
    23881 gtctggtatt cttcaatcaa tgcaggcgtc ttttcttcga tctttttcga ataatcattt
    23941 acgattgctt gaagttgctc tggcaaacca tttgctgttt tttcttcaga agtttgtgtc
    24001 tcttttgttt tagttgatga ctcacttgtt tgtttcgtct ctgttttctt tgtcgttgtt
    24061 tccgttatgg tcgtactttt cgcttctgac gaattttttc catgaaaata tagacccgca
    24121 actcctcctg ctatgatcaa aaacacggca actgctgccc caatcatgat catccgctta
    24181 cgagctgcct gtttttgctg tcttcttcgg gtcatccgaa cattttctcc ccactcattt
    24241 tcatcataca tttttttcac caccaatttt tatgtataat agcgttatca aacgcttcat
    24301 attcttattg tagcaaataa ttgtcgctgt gcacattttt atctttgtta tttataagaa
    24361 aatttcacca gttgagatga ttccaagatt gtccgtcgat ttctccttgc agctgcattg
    24421 ttcgttcgtc tatctcagcc atcagtttct ttatttcata taagagcgca cggtcttgat
    24481 attctgattt ttcgcttaat tcatctaatt gttggatcag ccaatcattt gtcataatga
    24541 agttcctttc atttcttgca gtgtaaaggt caagtcttcg atctgctctt ttgcctcagt
    24601 cagtgcttct acgatatatg cttgtttttc agattcttct tcctgcattt tctgattttc
    24661 ctgtactctt tgaataaacc agtcaatccg ctgagtcagc gatggtttgc cttccaatga
    24721 gagatactgc tgataagcaa ttagcttctc ccaacgtttt tcctgggata aatacataaa
    24781 ttgtgctaaa acgaatggcg gaagataggt catatggaat ttatttgcga ttcgctgata
    24841 cggcctcaaa aattcggaaa tcgtatattc ttcttttcct ccagcttggt attctttttc
    24901 cgccacacct gttgtcaata cgattcctag ttctttccct tttaatacat gtgctgctcg
    24961 ttccaagaca ttatcttgcc aaatttttaa atgagcagga gaactatacc agtaaaacgg
    25021 aaactggaaa atgatccgat catgctgggc caagagctgt agttcagtct ctatatctat
    25081 ttttccgtct ggataacttg attccaaatg atgccaagta gctggtaaac cagcagaagc
    25141 ttctttgaaa aattgctgat ttaaagattc ttcgatcgtt ggatggctaa tgatgataag
    25201 tgtacgcatc ccttttcctc ctttttagtc ttcgctttac agtgtagcat aaccgccaca
    25261 agtttctttt gccgatgctt gtcattttaa ccagactaat caggttgtcc aagaaactgc
    25321 ggtttgtttt tccaactgtt ttttcaaggt atccaaagca atattcttaa aattttcgtt
    25381 tttcatacgt ttacgatagt tcgtagccgt ttctccggta ctctttttga acattcggct
    25441 aaatacgact agactattga accctacttg ataggcaata ctttccacgg attcatccgt
    25501 cagagaaaga agaaacgccc ctcgattgat ccgtaccccg atcaaatatt ccttgatact
    25561 ggtacccata tgatttttga atactcgcga caaatggctc cgattgaccg ctaaatgctg
    25621 ggcgatttcc tcaacagaca atttttcagc ataatgtgcc tcgatgtatt tgactgtttc
    25681 aacagctaaa gaggaatgaa ccttttgtac accaccgctg acctttccgc catcttttaa
    25741 aaggactgat aaaaaacggt aggttaatgc tgttaactgt aattcatttt ccaaggtttc
    25801 ttccgtatct ttcatgcatt ctaaaataat gtcgatatat ttttgtatgt cagaagagac
    25861 catcgtgtat tggtcttctc tgaaaagcga ctgccgaatg atttcttctg cagcactccc
    25921 accaaatgaa agccagcaat acatccacgg atcttctcca tctgataagt aaaacgtcga
    25981 gtctcctgga cgaatcaaga acagatcacc ttttttcaat tggaattgtt gatttttcac
    26041 atgataagat cctttgcctt ccatcacgac atgcaggatg taatcattgc gaatagcagg
    26101 accaaaagaa tgaaacggca tcgttttaga gaaaccacaa aaatcaaaat acaattcttt
    26161 ttctacttgt tgatgttcct tttttaaaaa aatcgattgc tccacgtcta tccctcctta
    26221 ctcctttagt ataatgcaac aaaaagttaa ataaaagtca cagaaatata ttaaaaagga
    26281 agcgatttct tgttaagttt aagtcattaa aagatctttg ttattcgttg taaccggttt
    26341 acttagtatt atatattgaa caggagagga atacagatta tgaaaagcaa aatgatccaa
    26401 cgtgtgtcct acgctttagg cgcttttgga cacgacacat tctatgttac attaagcact
    26461 tattttatgg tattcgtgac aagccagatg ttcgcaggaa cagataaggc aacgaatgca
    26521 aaaatgattg ctacagttac aagcttagtt gtaggtatcc gcttagttga aattattttt
    26581 gatcctttga ttggtggcat catcgataat actcgtacaa aatacggtaa attcaaacca
    26641 tggttagtta tcggcggcgt tgttagttcc gtactcttgg tagcaatctt taccaatttc
    26701 tttggcttag ctactcataa tacgacttta tttatcatat tatttgcaat cgttttcatc
    26761 ttattggata gtttttattc atttaaggat atcgcttttt ggtcaatgat tccagctttg
    26821 agtacggaaa caaaggaacg tgaaaaattt gctacgtttg ctcgtttcgg ctcttctcta
    26881 ggtgcaaatg gtactactct agtcgttgtc cctatcgtta ctttctttac ctatcttgtt
    26941 actcataaac atattgaagg cgcttcaggc tggttctggt tcggtgtgat tgctgctgtt
    27001 atttcaggcg gtactgcgat tatcactgcc ttgggcacaa aagaagtcga tactgcgatc
    27061 cgtcagcaaa atgaaaaagc tgggatcaaa gatgtgttca aagcagttgc tcaaaatgat
    27121 cagttgatgt ggcttgccct tgcttatatc gcttatgcga ttgccaatgc agcaacaact
    27181 gccgtattat tctacttctt caaatatgta cttggccaac caactgaatt ttggatcgtt
    27241 ggtctagttg ctgccttact tggtttagta gctgttccac tattcccaat gcttacacgc
    27301 gtcatctctc gtcgctacgt ttaccttgga gggatcgcaa tgatgatttc ttcttacttt
    27361 ttctttacga tcgcaggttc aagtttgcca atcgttatca tcgggctagt attgttctac
    27421 ttccctcaac aattgatttt cttatccgct ttgatgacga tcacagactc tgttgaatat
    27481 ggtcaatgga aaaatggtat ccgtaacgaa gctgttactc tatcaattcg ccctttacta
    27541 gataaaatcg ctggtgcttt gtctaacggg atcgtagggt ttgtcgctat cgcttctggg
    27601 atgactggta atgctactgc tgctgatatc actgctcatg gcgtaacgac tttcaaagct
    27661 tatgcattct atgctcctgc tgctttgatg attttctccg ctattatttt tgcttggaag
    27721 attacattga cagagaaaaa acatgcacaa atcgttgaga aattggaaaa caaattggct
    27781 ccagctgata caatggaaga ttaacttcac gatgcagtag ttccttccca ttaagaaagg
    27841 atcttgaaaa tgaagattac agaaaaagat tttggccaag gttatcactt gataaccttg
    27901 gagaacaaaa acaagctagc actttctatc tctgatttag gtgctagaat cgtcagttta
    27961 aaatcaaatg atcgagaatt agttttggga tttgacaccg ctgaagaata tatcgaaaaa
    28021 gatccgtata tcggtgcttc tatcggtcgc accgcaggga gaatcgaaaa tggccgcttt
    28081 tctctcaatg gaaaaactta ccaattagcc acagatccaa aaactggaca taatctgcat
    28141 ggtggtgctc ctggatttga attaaaaaaa tggtcttatg tcattttgaa tggcgaaaat
    28201 gaagcttctg tcatttttac tactacaagt cccgacggag aacatggttt tccaggtaca
    28261 atggatgtgg aaatccgcta tactttgaca aaagataata tctggcgagt gacctctcgc
    28321 ggcaccagtg accaagatac tttattcaat ccgacaaatc atgtttactt caacttgacg
    28381 ggagatgctt ctcagtcaat cgatcaacat gagctttggc tcaatagcga agcttatgct
    28441 cctttgcgaa cagatagtat tcctataggg gtaaaagaaa atgctgcagg aagtgctttc
    28501 gattttcaaa tacctaaaaa attagcgtcc gtttttgcta gtgatttgga tcaaaaaaat
    28561 cttgttgacg gaatcgatca tccatttttc ttaaaagaaa ccggcttggg taaagaagcc
    28621 gctcgcttga ctagccccga taaaagaatc caagtagata ttgctacaga tgcttctagt
    28681 gtggttattt tcactgcaaa tttcggcaca gaaacaccag aaatgcgcaa ccgaaaactg
    28741 gcacatcacg gtggcatcac atttgagact caaacagctc caggtgcaga gcgcttctca
    28801 gcatttggtt cgattcattt aaaagccgga tcagtatttg aaacagtaac agaattcaaa
    28861 atcaaaacaa gaaaggaata actcatcatg gaaatcaaaa gaagcttaaa cacaaaattt
    28921 gccgaaacat tcggacctaa aaaaactaca caatacttct caccaggacg catcaatttg
    28981 attggtgaac acacagatta caatggaggc catgtcttcc ccgcttccat cacttatgga
    29041 acgcaaggtg tagcagcacc tcgagacgat aataaaatat tagtttattc cacaaacttt
    29101 gacgatatcg gtgtcattag ttttacttta gatgagctag aatatgataa aaaagcaaac
    29161 tgggcaaatt acgtaaaagg aatggtcctt aaattaaaag aagctggaca ctcaatcgat
    29221 catgggtttg agttattagt ggaaggaaca atccctaatg gtgcaggact ttccagtagc
    29281 gcttcattag aattattagt aggtgttgta ttagaagatc tgtttgattt aaaaacagat
    29341 cgcttggaac tagtccaaac aggtaaaaaa gtagaaaatg aattcatcgg tgtcaattca
    29401 ggtatcatgg atcagtttgc catcggcttc ggtgagctag atcatgcaat cttattagat
    29461 acaaatacgc tgaaatacga aatggttcca gtgaaactag atggttatgc aatcgtcatc
    29521 atgaatacga ataagcggcg ggaattggca gattcaaaat acaatgaacg ccgtagcgaa
    29581 tgcgaagaag ccttggcacg tttgcaaaaa actttgccta tctcttcttt aggagactta
    29641 gatgaagaag aatttgaatc aactattgac caaatcggcg atgatacatt gatacgcaga
    29701 gctcgccatg ccgtttctga aaatcagcgg actttgaagg caaaagctga attagaagct
    29761 gggaacttag aagcatttgg tcaactgtta aatgattctc accactctct tcgctatgat
    29821 tatgaagtaa ctgggatcga attagataca ctagtagatg ctgctcaaaa acaagaaggt
    29881 gtcttaggtg cacgaatgac aggagctgga tttggtggct gtgcgattgc tcttgtcaaa
    29941 gaagaaaata tacctgcctt caaaaacaat gtctatgatg aatacatgaa agttgtcggc
    30001 tatgctccgg aattttatgt tgcacacatt ggaaatggga caacaaagat cgatccagaa
    30061 gctgttcatg tttgataaaa aaatcaacga tctcagctaa aaacaaatag ataaaaataa
    30121 cctctcagca atttccaaat gtgagccttt tgctcgtatt tgaaaattgc tgttttttat
    30181 tgacacggaa agagaacgtg tgttctaatt gtgttgaaga ggtgattgtt atgtgggcga
    30241 atcaaaatcc ggtatttgtt tatgaaaaag aaccttcaag agatatttta tgtattgact
    30301 gcaaatcttt ttacgcctcc gtagagtgcg ttgaaaagga tcttgatccc cttacaacta
    30361 aattagtagt catgtcctat ccgtccgatt cgacagaaac acggggtagc ggattaatct
    30421 tggcttccag tcctgcagca aaaaaagctt acggcatcac caatatcagc cgtgccagag
    30481 atcttccctt cccctatcca agtgatttat atattgttgc cccaaggatg gcctattata
    30541 tggaaaagaa cagagaaatc aattctatct ataaaaaata tgcagacgaa gcgaaccatc
    30601 atgtctattc cgtcgatgaa agcttccttg atgtaacaaa tagcatggca ctctttggta
    30661 aaacaaatgc gtacgacatg gctaaactga tccataaaga tgtgtttgag cagaccggaa
    30721 tctacacgac tataggaatt ggcgataacc cgctacttgc taaactagcc ttagacaatg
    30781 gctcaaaaga cggaaagcaa atgtttgctg aatggcgtta tgaagatgta ccagaaaagt
    30841 tatggaaaat ctcagatatc actgactttt ggggaatcgg caaacgaaca gcaaaacgtc
    30901 tgaaacaaat gggtatacat tctgtttatg atttagctca cgcggattat tatcacttga
    30961 aaagcaagct aggggtcatc ggtactcagc tttatgccca tgcttggggc atcgatcgaa
    31021 gttttttggg acaagaatat acaccaaaat caaaaagtat cggaaatagt caaatcctag
    31081 atagagatta tacaagacga gaagaaatcg agatcgttat caaagaaatg gccgaccaag
    31141 tcggcactcg cttgagacga tctgcagcaa aaacacaagt agtcagctta tgggtaggat
    31201 actctttagg ctatcttgat ccaaatggca agaccgggtt tcaccagcaa atgaaaatcg
    31261 aagcgacaaa tgctagcaga gatcttgcag atgctttatt gaccattttc caccagcatt
    31321 accactacca ggatattcgg cgtgtaggcg tgaactgttc cgacctcgta tacgcgacag
    31381 gtttacagct taaccttttt gaagatcctg aaaagcagat aaatgaagcg aaagttgatt
    31441 ttgttgtcga tacgattaga aaaaaatacg gctttcaatc aatcatccat gcgcatagtc
    31501 tcttgcaagg aggacgcgcc atcgcacgta gttctctcgt tggcgggcat gcaggtggta
    31561 tgagtggatt agaaggtgga aaagatgaga cggacagcaa aaaaattcat tgactataac
    31621 gagtatcgag atcggccatt tggattaaaa tgggggactg cttttgcgat ggaagaacta
    31681 gtcaacggta tcaaaaaaat gaagaagaag cacgcaaaca gcctcttcct aaacaacaaa
    31741 tgacattgca agaaatcgat agtatactga cagaagcctt tttatctcgt aaagcagtaa
    31801 tcattcagct caatttaaaa gatgaatttg gaagactctt ggatgaggtc gaagggcact
    31861 tcattggtga agcctatgaa gattacttta tgattgacca tcagccgata ttgtgggaag
    31921 acgtacggta tattgagtta aaggaaacaa aaaaatggtt tgtgacatga gaggttgtga
    31981 cagaagtgat caacttcaaa aaataagaaa ggatttttcg aaaattgctt cttaaatttt
    32041 tgtggaattt tggcttattt ttcgaagaag caacttctgg aacaacgtat attagatatc
    32101 agaggttgtg aaaaagtcgc ttagttttga gtaacaagcc aaggcgctga tttcacaacc
    32161 tctgtctatc tatccatcta ttcggtaaga ttcatgcatg acgtcttctt tatttagtat
    32221 gtagagccct ttttcttctg accattcaac ataaatcagc tgttttacat ctgcatagcc
    32281 ttctttcttc aagttctcca taagccatgc ttcagtcaat tgattggact gaagcacttt
    32341 atgctgaatt tgcccttcat ctacaagcag gatcgataaa gctttgtctt catctgattt
    32401 tttcaataca ctcatttgac cggcattctc taggataaca tgtttggcat tttcaagaaa
    32461 aaagcattct tgctgtctta agattgctcg caactgctcc atctcgatat ggttatttgt
    32521 caactctgtc atgttgatga cgccgtcttt gattagaaca gatggctcgc ctttgaccca
    32581 acgattgacc ttttcatttt tttggacgat acgttcgata ccataaatca ttactgccca
    32641 aagcgcaatg gcaaatagga catgccctac atggacattg tcatcatagg ttgattcttc
    32701 taagatccca cctaaaacaa gcgtatagac taaatcaaac ggtgtgattt ctgacatgga
    32761 tttcttccca agcaaacgta ccactaataa taaaccgatc aacccgaaca ccagtttcat
    32821 tgtaattgaa aaaatcattt tttctccccc taactatctg ttaattaaat tatatatgct
    32881 ttctcacgaa cacgcatgga atatacaagg aagaaatgta tccttttact aaaaaaagga
    32941 ctgtgacact gtagtgaccc ccaaaagtta gacttttttg gagtggagaa atccactcct
    33001 tttttttatg ctctaaaatg atatttttac acaaccgtta cggttgtttt acgaaattgg
    33061 acgagacttt gccagtttaa tttctgtttt atccgttcat tattgtagta atagatatag
    33121 ctatcgatgg ctgattttaa ttcctcgaaa cagttataaa ctttcccgtg aaaaatctct
    33181 tgttttaata agccaaaaaa attctccata agtgaattat ctaagcagtt ccctttccga
    33241 gacatgcttt gaaagatttt gtactccttc aatttgtttc tataagcttt catttgatac
    33301 gcccaacctt gatctgagtg aaacgtacga cgatagggac aatcgttagt ggtctggata
    33361 gcttcctcca aaccttccat taccgctaat gcattgggct tttcagagat acgataggat
    33421 aaaatctcac tattgaacat atccataaaa ggatctagat acaatttctt ttgacggata
    33481 atgcctttgg catccacttc atggtattta aattcagttg tatccgtcgt gattttctga
    33541 tggcagatac tggtgtagaa acgacgatgg atccgatttt tggctactgc tccaactttt
    33601 cctcgataag aattgtagcg acgtgattta cgcgtgtatg ccgttacttt tattcctagc
    33661 ttcttgatca agcgctgaac tttcttttta ttgatagaga aaccgcggtt tcttagttca
    33721 ttggtcatcc gtaaacagcc ataatccttg tgcttctccc gaattttaag catttccgct
    33781 tcaatctctt gatctggatt tttacggtcc aatcgccttt gccatccaaa taatcatgaa
    33841 cgatctttaa tttaagttca aaagtatatt taaccataaa aaataccgac ctccaaaagt
    33901 tagatttttt ggtctaactt ttgggggtcg gtacacaaat cgtgtcacag tccctttttt
    33961 gaaaataaac ggtgttcaaa agcttgcatc tgcggtaata agtccagcca agttaaaaac
    34021 ataagaagct gtttttactt ggctgttctt attacttgat gcaaggcagc tttttcacaa
    34081 cctcttttca aatatttcgt tttcttattc tacaaatggt tcttctccta acgcttgttg
    34141 agcggctaga ttcaacatgc tccattgtcg gtcaaagcct ggctggaaga agaagtcagc
    34201 ttctgctagt tcttctaaag tcagtttgtt ttggatcgct agtgccaata catttccttg
    34261 acctgtaaca tcataggtag ataatactgc tcctcctagc aattgatggg tcattggatc
    34321 cgagaataat tggatggaca cttttggatt tccttgttct tctggtacat attttggtcg
    34381 taacgtatct tcataataag acactcgtac atctactcct gcttttgctg ctgtaaagct
    34441 attcaatccg cttgctgcaa aatgatagtc aaagacactt aatgcagagg aacctacgac
    34501 tccgccgaac ggtttgtttg gtacttcttc aaaaagatgt tttactacat aacgtgcttc
    34561 tctacgtgca acagtcgcta aagcgatcgg catttttttg cgtgctggga tagaataagc
    34621 aagtgtagca tctcctactg catacacatc tggaagattc gtttgcaagt attcatttgt
    34681 ttggatccag ccacgttcat ctaagtcgac gatccctttt aaccattctg tatttgcctt
    34741 cacaccggca gcttgaatga ctagatctgc tgggatttct ttttcacttg ttttgattgc
    34801 ctcaactttt ccgttaccag taaaagcttc gatttttgca tttgtcaaaa cttcaatacc
    34861 gttttcattt aggtgttgtt ctaaaatatc tgtcatctca gcatctaaat aagtgcctaa
    34921 aggtctatcg atcacatcaa gcaatacgac ttctttccca gcttttcggc ttgcttctgc
    34981 tgcttcgatc ccaatgtaac ccgcacctac gacagcgatt tttttaatag ccggatcatt
    35041 taatttttct ttgattttgg ttgcccaatt gtatccacgc atcaagtaga cattttctag
    35101 atctgctcct ggtactggca gattgtttgg tttgacacca gaactcaaaa tcaatttgtc
    35161 ataaggatat tcttttgttt cgttatctga tgcgctagta accgttactg tttttttatc
    35221 ggcatcgatc gtttttactt cgtgattatt taaaatatga acattggatt gcggaaagtt
    35281 ttctggtctg aaattacgta catcatttac atctgttacc ttgtcttcta aatacagctc
    35341 cataccacat gacatgaagg aaatatagtc tcctgcttca aatagcgtga tatctacatt
    35401 ttcaccgtat cgtgtcaata gttccaagat cgattgatgc cctccatgag atgcacctac
    35461 aatgacaact ttgatttttt ccattgatga aacctccttg aatattcttt taaaatcatt
    35521 ctaaacaatt taaacttaac attacattag ttatgaatca aaagaaacgc gttcatttga
    35581 actaaattta aaaaacaatc gtctccttgc agaatatacc gcaaaattaa cgattgtttt
    35641 tttgataaaa tctatgaatc actgttctgt taaaaagtct ttgatccgtt tgcaggcctc
    35701 atgtaatttt tccatgctgc tagcataaga aatccggata taaccttctc cttctgggcc
    35761 aaatgcaatt cctgggatac acgcaacttt tgcctgttcc gctaattcta cacaaaactg
    35821 ccaagagtca gtttgaatgg cagctgggag tttgcaaaac aagtaaaatg caccgtttgg
    35881 ctgggtcact tcaaatccta aaggcgccaa ttgctggacc agatagtctc ttcgtgtttg
    35941 atattgctct ttcatattct cgctatcttt caccccattt attagcgctt cagccgcagc
    36001 tttttgcgac atcgttgtag cggcagtcac cagatattga tggactttaa ttagttcgtc
    36061 aataagggct ttttgagcaa aaataaagcc cactcgccaa ccagtcatcg catgtgactt
    36121 ggataacccg cttatcacga ttgtttgttc tggaagataa gtagctatgg acatatgcgt
    36181 tccactataa gtcaattcag catatacttc atcacttata acaaataccg gatatttttt
    36241 taaaacctca gcgattgctt tcaattgttt tgcagacaat gtcgtcccag taggattgtt
    36301 aggatagttt aaaatgactg ctttgacagc tgatccatat tgttcaaatg ctcgttcaaa
    36361 ttgttccggc tgacagacaa accctgtgtc agaagtatct atcgggatca attcagcacc
    36421 agctagttcc actaatggct gatatcctga ataagcaggc gctggaataa gaaccttgtc
    36481 tccttcttcc aaaacagata acaacgcaga ggcaatcgct tccgttgcac caactgtcgt
    36541 caaaacttcc gtttgcggat cataagttaa tccataacgc tgttgctgaa atatacaagc
    36601 cgcttcccgc agttcctcta atcctctcat tccggtatag tgagaaaagt cttcttcaat
    36661 cgctgctatt cctgcttgct tgacatgttc aggagttgga aaatccggtt ctcccagggt
    36721 gagtttgatc acatctggta tcgacgatat ttgctgatcg aattgtcgta tttttgatac
    36781 ttctattcta gaaagcctag gactaaatcg attggataaa ttcatcatta tttactcgct
    36841 cctcttttga actgctatcg atttttacaa gaagattttc tgtaaaaaga atcgttttgt
    36901 accattctac accattttct aaaacatcca tatcaaaatc gaacgtcgga tcatgtaaag
    36961 caggggtatc accgacacct aaaaagaaaa atacacatgg atattgttgc gtatatatgc
    37021 caaaatcttc ggcttgaaga actggagcat ctaattcatg tagtttgttt gaatctaaca
    37081 gtgctgcata taagcctcta tggttgatta cagctggata gccgtcatta tagcgaaaag
    37141 aaatagtagc tgtagagtga aactgttctg ctaaatggtc taatcccctc ttcaaataat
    37201 tttgcatatc tgaactgtaa gaacggatac ttccggatac aataacttct ccagctaaaa
    37261 catttcggat cgttccacct tggatttggc caaatttcat tagatgattc cactctgccg
    37321 gtaattgccg gtcaaaatca taaacattct tcaaaaatcg tacagctgcc tccagactat
    37381 cgattccttt ttcactagaa gcaatatgtg cagactggcc tttaatgata atgtctgttt
    37441 cactgctttg tgccatcaaa ggtcctggtc gagagaaaac ttctccctta gctagtccag
    37501 gccatagatg aaagccaaat attgcttgta cttcatattt atccaacaat cctgactgaa
    37561 taacgctttg tgcgccaccg gaaatttctt ctgatggctg atagatcagt actacattat
    37621 aaataagatc ctcaatgtgt ttagttataa agtcagtcaa ccctaaaagc atcgccatat
    37681 gtccgtcatg accacatgca tgcatataac cttcatgctt agaagcaaaa gagagattcg
    37741 tttcttcttt gactggcagt gcatcgatat ctgttcgaaa agcaatcgtt tcttcttgct
    37801 gattatcaaa ataaaggagt agtcctgttt cgccgatttc atggataacg gcctcgctgt
    37861 tttttacttg ttcatataaa tatttttttg tcttgaattc atgaaacccg atttcaggaa
    37921 tttgatggag tgccattcga tattctttca gcatccgtat tcaccatccc ttcatagata
    37981 cccttcacta ctgtttcata ttgattattc ggtacaccga tgatcagatt caactcctgt
    38041 gctccttgtg ataagatcga tgtgcgaatt tctaatttgt tcaatatcga taacactttc
    38101 ccagataatc caatcaattc tttatgcgga cccccaacga cagagatcaa agctaagtct
    38161 tcgatcacga cgatttcttc cacgccaagt gtttctttta attctttcgt gatgagaaat
    38221 aacttatcgg caatcgcttc tgctgagacg atcactccga tattgtcgat ccctgaagga
    38281 atatgttcga ttgatatctc atgtttagca aaaatgctca ttgctttcca gataaacccg
    38341 atttcatcgg acatatgacg tttgaataaa gtgatggaaa gaaaatcctt gcgtccagct
    38401 attcctgtca gtccattttc cttttctatt tcgtgattcg atatttttgt cccttgagcg
    38461 aaaggatcat tggtattttt tatttggatg gggatatcag cctcttgaac tgggaaaaca
    38521 gctgcttcat gaagaacgtt agcccccata taagccatct ctctcagttc tctaaaagag
    38581 atttcctcga tgattttagg atgatcgatg attcgcggat cagccatcat gattcctgaa
    38641 acatccgtcc aattctcata actttccgct tgcaacatct tcgccagtat cgcgccggta
    38701 atgtcgcttc ccccacggcc caataatttt tcttttcctg cagggttcgc cccgtaaaac
    38761 cctggaacaa ccattttcgg atatctttta aatgcttttg tgatttcctg tgctgttttt
    38821 tcctgatcga ttttcccatc atagtcaaag aaaatcaggt cttttgcgtc aataaactgg
    38881 taaccaagat actcagccat cagttgagca gtcagatatt cacctctact tactaaataa
    38941 tcttcagtta tcttttcgtc ttccagttgt ttctgtatgc gtgctagttc atcttcaata
    39001 ggtaactgca gggcaagaac atctcttact tgaatgaaac gatcacaaat ccttttccaa
    39061 aggggtgtcc aatcaacatg atgctgaagg taagcataaa tcaaataaag taagtctgtt
    39121 actttgtcat catctgacgt acgtttgcct aaagcagaaa caacgatcac ttggcgattg
    39181 ggatctgaaa gaacaattgt acggactttt ttgaattgct cttcatgaga catcgatgtt
    39241 ccgccgaatt tcgctacttt cagcgtatta ctcatcttgc cacctccgct attttctgca
    39301 ttaaagctgc agcaatctgt acggcattcg cagcggctcc tttgcgtatg ttatcggcag
    39361 tcgtatagaa caacaatccg ttctctaaag aagtgtcttt tctgatcctc ccaacataaa
    39421 ccatatctgt tcctctagca agaatgctcg tcggatattt atgtgctgct agatcatctt
    39481 ctaattgaat ccctggaaac tggctgagac actctctaat ttcttccgtc gtaaactctt
    39541 tttgcagttg aactgccaca gagactccat gtccattttc gattggcaca cgtacgcagg
    39601 ttgctgatac tggcaaagca ggctgatgca gaatcttacg ggtctcattt atcattttct
    39661 gttcttcttt tgtataccca ttttccaaag gctgatcgat ttccggaatc accgtttggc
    39721 taatattata aggatacaaa actggttcct cgtcattttg cgtacgatga agatcttcaa
    39781 tgcctttttg cccggaacca gaaactgctt gataggtcga ataattgact cgctggatac
    39841 caaaggcttc ttgtaaagct ttaagcggaa gtaccgcttg aatggttgaa caatttggat
    39901 ttgcaatcag ccgattcaat gtatagtctt ccagattgac ctctggaacg attaatggaa
    39961 tatccgaatc ttcccgccat gctgaggaat tatctatgac aaatagtccc tgacttcgtg
    40021 cgattggcgc aaactctttg gatacagaag cacctgcaga aaatagcgct aaatcatatc
    40081 cttcaaatga agtttctgtc aattcctgta cagtgtgttt ctttttcttg aatacacaaa
    40141 ctttaccggc tgaacgtttt gaagctaata atttcaatcg tcctactgga aaatcatatt
    40201 cttctaacac tttgagcatc gtttggccga ctaatccggt tgcccccaca atacaggtat
    40261 ctatttcgcg catttttctc catctcctct ataattcgcg taacgcagca atcaatgctg
    40321 tattttcttt tgtctgatca tcacttattt ttaatacacg tgcaggtatt ccaccgacaa
    40381 cagtttctgc tgccacatct tctaaaacca ctgctcctgc tgccacgact gcatcttttc
    40441 cgatatggac accttcaaca atcactgcat tcgcacctac cagtacgccg tcttctacga
    40501 taaccggttt ggccgatgct ggttcgatca cacctgctaa gacagctcct gcaccaatat
    40561 ggcagttttt gcccactgtc gctcgtccac ctaagacagc acccatatca atcatcgtgt
    40621 tttcaccgat tactgcacca atattgataa tcgctcccat catgatcacg gcattgttgc
    40681 cgattgacac ttgatctctg ataatagcac ctggttcgat acgagcatta atttttttaa
    40741 tatctagcaa aggaactgcg ctgtatcttg cagcagtttc gatttcgatt tcaatgattt
    40801 tttctgattc agcttctaaa accggagcaa tcgtctcata gtcaccaaaa acaacgaagc
    40861 tgcttccttc accaaaaact ttactttctt taaattcgat tggctcggtt acattcagat
    40921 agactttcac aggcgtcttt ttagatgccg tttgaatgta gcggatgatt tcttgagctt
    40981 ccacgttttt tacacccctt tgtccattaa taaatcttct aatttgtaat aacctggtga
    41041 ctgatctttc aaccagtccg ctgcttctac tgcgcctgca gcaaagattc gattagaaaa
    41101 agattcatgt ttgatcgtaa atatttcatc agtagcagca aacaatacat catgttcacc
    41161 aggtaaagaa cctgcacgaa tactgtgtac accaatttgg ttttcttctc tttttttccc
    41221 ttgccagttg tatacgggct gcagcttttg cacttcttgg attgtttgaa gcagcatatt
    41281 tgcagtacca gatggtgcat cttttttacg actatgatgt ttttcaatca gttcgatctg
    41341 ccagccttgc aacattgcag ctgcttgctt gattagttga ttcatcacca tgatgccgaa
    41401 cgaaaaatta gcactataca tcacaggtac atgtttggca tgttctttta tttcttggaa
    41461 ctgtgattgt gtataacctg tcgtgccaat gactaacgga agttgatatg ataagctata
    41521 cgaaaggatt ttctctaaat tatctggatg agaaaaatca ataagcagtt ctggcagttc
    41581 cgtaaaagca agcgtagttg cttctttagg tgccgtccgt aaaagaagga ccgtatctcc
    41641 tctttcttgt gcaacttctt cgactctatt tcccatctgt ccactgccaa tcagtccgat
    41701 tttcattttt caaccgtcct ttcttttaac aaaagctgag ctaattgttt ctttttctct
    41761 tttgaaagag aaactaaagg caggcgtaga ggtccggaag gtaagtctaa taatgacatg
    41821 gctgctttga caggaatagg attggtctca ctgaacaagg catggatcag ttcaagtgca
    41881 tttaattgct tttcttttgc ttgctgccat cttccgtcct gcgtatcttt tactaattca
    41941 tggactattt taggttggat attcgcccat acacttatta caccgcttcc tcctacactc
    42001 attactggta ggatcaaatc atcatttcca ctgtaaagga agaattcttc tccaatcaac
    42061 cgagcggcat ccatcacata agccatatct cctgaggctt ctttcaaacc aatgatatta
    42121 ggatgttctg ctaaatttac taatacatgg attggaatcg acatgcctgt tctagaagga
    42181 acattataca aaataagcgg aatcggtgag gcttctgcaa ttgctgtaaa atgagcagct
    42241 agtcctgcat cacttgtttt gttgtagtaa ggggtgatga ccaaaagtgc gtctgccccc
    42301 aaagaagcaa aatgcttcgc tttttcaatc gtttctttcg tattattcgt tccagctcct
    42361 gcaatcaccg gcacacggcc agccactttc tttactgtca gttgaaggat ctgctcctcc
    42421 tcagattgtg tgagcgtaga agattctcct gttgtaccta aaactaataa tccatctgtt
    42481 tgttcatcta aatggaattg gatcaatttt tccaaaccag cataatctac tgatccctct
    42541 tcattcatcg gcgtgatcag cgccacgatc gaacctttta tcatcttcat tcctccaata
    42601 ttcttgtcca ttcatgaact gctgggccag ccatttgtat cgcatcctca ccagagatca
    42661 tcaagtctcc ttgttccaag tgaacaacta cctgatctgc tgaaattttc ccagtttcct
    42721 tagcaaccac ataagaggca cagcaacctg taccgcaagc aagtgtccaa cctactcctc
    42781 tttcataggt acggacgatc aattcttgtt cattgactac ttctacaaag ttgacattgg
    42841 ttttttcttt gaacaaagga tgatgacaga tcagttcacc tctttttctc cagacttcct
    42901 cacgcgcatt ttcaacaaaa acaacggtat gaatcgttcc taaaaataaa ctagtgatcg
    42961 ttactttttc accattgatc tctatttcct ggttttttat tggataagtt tgattagctt
    43021 tgattttttc cggagaatca tctggcactc ccatatctac gctgcaataa aaaggtgagg
    43081 gatccaacac cgtaattttt cttgtgcctg ctaatgtctc tacgttgaat tcctgttcat
    43141 tcatcatgtt ctgatcattt acgtatcgag caaaacagcg aatgccattt ccgcacatcg
    43201 gcgcgcggct gccatctttg ttgtaataga tcatttccaa cggatcgatt tttacggcga
    43261 tcaatccgtc tatatcatat ttttcttttg tgcataaaga agcggctaat tgactataat
    43321 ctgtgtcttc tgcgtaatct aataagataa aatcatttcc gcagccatta tatttatgaa
    43381 ggatcatagg aaacttcccc ccttagtaga tcagaaaatg cttgtctgcg aacaatcagt
    43441 cttgattggc cattattgac aaaaacaact gctggtcgtg tcgctcgatt gtagttgctg
    43501 ctcatcgagt atccataagc tcccgtggaa taaacagcta aaagatcacc cgattctgct
    43561 ttcggcaaat aagcttcttt aattaccaca tcgcctgatt cacacatttt tcctgcaatc
    43621 gtcactttct ctgttttttc ttccgacagt tttgctgcta aatcacaatc gtattctgcc
    43681 tgatacagag ctggacggat attatctgtc atcccgccat ctacaaagta atatttttta
    43741 tgtggtgtct ttttgatgaa accaatcgtg tatagtgttg taccagcttc tccaacaata
    43801 cttctacccg gttcgatcag taattgacga atggtcagtt ttcgtttttc caaagcttct
    43861 tccgtatatt caatcagttt ttttagtgcc tcttcgactg ggatcggctg atcattttgt
    43921 gtataacgaa tcccaaaccc tccgccaaga ttcaaggaaa gaggttggtc aaaatcggtt
    43981 aagtaattcg tcaatttgtc gatttcagct aaccaagcag taacatcaaa aatttgtgac
    44041 ccgatatgag catgaaatcc ttctaactct agatagctgc tttcttttat caactgaagg
    44101 gcttgttggc actctttact ttcatagctc atgccgaatt ttgaatcaat atgcgcagtg
    44161 acgatatatt catgagtatg tgcttctact ccgacattca accgaagcat gatacagatt
    44221 ttttttaaat agcgttggct taattctgct aataattcaa cttccatcaa attatcggca
    44281 acaatatgca acaaatcatt ttcaagtgca tagatcagtt cctctggcgt cttgttgtta
    44341 ccatggaagt agatagtatc tctaggaaaa tcagcttgca aagcggtata gatttcccca
    44401 ccactgacaa catctagccc gaatccatat tcacgaacta aatgcagcat ctcaatcgtt
    44461 tggaatgctt tagaggcgta aagcactttt gtatcaaaac gtttcgatac aaagcctcgc
    44521 ttgaatgaca gcatcgtttg tctcatcttt tcttcatcat acacatacag aggtgtctta
    44581 tacttttctg ccaatgtgct tgctgtgact ccgccaatta tcaattctgt cattttttca
    44641 ttcctctttt cacttttttt ccgtttttat tggaatttca tttgataaag atttgaattt
    44701 tattggaata atattaaaca aaattttctg aattgtctag tatatttcga aatatttttt
    44761 taaaaataag aataaaaatg gttataaaaa caaaataccc gaactattag aagctattta
    44821 tacataaaaa cataaattca acactattta gtgatgaaaa aatattttcg cttcaatata
    44881 gttcggaata gttcggatat tttcaatttt atgaatcatt tcaatttctt cataaataag
    44941 tgcagttttt tctttctcta gcttttgcca ttcatctttc aaaatataaa taaaatcaaa
    45001 tactttttta tttttcaatt tgctgattcc acaaaaaacc tcttgaaagg cagatccgat
    45061 gatctgcctt tcaagaggtc aagctctgtt ttcaaattct tatcaatccg ttagcgaatt
    45121 attttgacgc acgttttaca taagaacctt ctgctgtatt gatttccaac aattcatctg
    45181 tttcgatgaa gtcaggaaca ttgactacta agccagtttc cattgtcgct ggcttacctg
    45241 aaccagtgac tgttgcacct ttgatggaag gttgtgtttc cacaacacgt aatacgacag
    45301 ttgttggtaa ttgaacgccg atgacttcgc taccgaaaaa ttggattttt acttccatgt
    45361 tttctaggat atatttcatt tcttcttcta ctgtttctac aggaatttca tattgctcat
    45421 atgtttccaa atccatgaag aaagctgtat catccatcgt gtacaaatat tgtacaggtt
    45481 ttgtgtcgat atgtgctttt tcaaattttt cttctggtct gaacgttgtg tcgtatgttg
    45541 cacctgaacg gacatctttc agtttcatac gcataactgt atttccttta ccaggtttat
    45601 ggtggcttgc atccagaact ttaatcagtt tgccgtcttg tacgaaagtc ataccggctc
    45661 ttaaatcact tgctgagatc attatttttg ctccttcttt tctttatcat aatcaacttt
    45721 attgtatcag acaaccggcc agaaaactag agtattctct atcttttaag gtctcatgcc
    45781 tatttgtcag aaaaataaac acgggtaaac gatgctatcg aaatattttt ttctttcaag
    45841 cctttgactt ttattttttt tcatgctatc gttaataaaa attttacttg gagggataca
    45901 catgacagtc agcaaccaaa aacaattgaa tcgttgctgt tgtatggtgc ataaaagcag
    45961 catactattt gtcatgtcta ttaattgccc ttcatagaat gagtaccagg taacttatct
    46021 ttttatctac tcaatttttc tctatgtctt tcaaggagct gatttaatag tcagctcctt
    46081 tttttattat ctttttttag gaggcccaca tgattatctc gacaattaca gaagctattg
    46141 gttccacacc gctttatcgc tttgacaatc agcactattc tatgcctaaa ggttctgcta
    46201 tttatgcaaa actagaatat ttaaatcctg gaggaagtat caaagataga ttgggcagtt
    46261 atttgatcaa agaaggattt gcccaaggaa aaatcaatga aaaaacgacg atcatcgaac
    46321 caactgccgg aaatacagga attgggatcg ctctggccgc actcacatac aaattaagaa
    46381 cggtttttgt tgttccagag aagtttagct tagaaaaaca acaattgatg aaagcattgg
    46441 gagcaaagat catccattct cctagtgagc aaggaatcat cggtgccatc agcaaaagta
    46501 aaaaacttgc agaggagata tcaaacagct atctgcctct tcaatttgaa aataaagata
    46561 atcctgctgc ttactatcat acgttagggc cagaaatctt tcatgaaatc aaagaaaata
    46621 tccatagttt tgtagcagga attgggagtg gtggaacctt tgctggaact tctacctttt
    46681 tgaaagaaaa atatcccgac attcgaataa tcggtgtaga accagagggc tctgtgttaa
    46741 atggtggtga tccagcccct cacgaaattg agggtatcgg tgtagaattc attccgccgt
    46801 ttctttctcc cctttcaatc aatcagatcg agacaatctc tgatgtagaa gggtttaact
    46861 atactaggca gttagcacga gaacaaggac tattagttgg aagttcgagt ggtgcggctt
    46921 ttgcagcagc attaagagaa attcgtcgtt taccacctgg tcatcgtgtc gttacgattt
    46981 ttccagacgc agcagaccgc tatttatcaa aaaacattta cttataggag gaaagaaaca
    47041 tgcacattca aacaaaattg atccacggag gcatcagtga agatcccaca acaggagctg
    47101 tcagtgtacc tatttatcaa acatccactt atcggcaaga tggcgtcggc cagcctaaac
    47161 aatatgaata ttcaagatct ggtaatccta ctcgttttgc attggaagaa ctgattgctg
    47221 atttggaagg cggtgttcga ggattcgctt tttcttctgg tctttctggg attcatgccg
    47281 ttttttctct ttttcaagct ggcgatcata tcttattagg agatgatgtc tatggaggaa
    47341 cattccgtct atttgacaaa gttcttacta aaaatggtct cgagtacacg atcatagata
    47401 cgagtaatct tgataaaata gaacaatcca tcaaacccaa tacaaaagca ctttatcttg
    47461 aaacacctag caatccgctt ctaaagatta ctgatttaga aaaaagtgcc actctggctc
    47521 atcaacatgg attgatagtt attgctgaca atacatttgc tactccttat tttcaaagac
    47581 ctttagatct cggttctgat atcgttgtcc atagcggtac caaatatcta ggcggacaca
    47641 gcgatgtagt agctggttta gtgacttcta accataaaga tctagccgat cagatcggat
    47701 tttaccaaaa tgctatcgga gccgtacttg gtccccaaga tagctggtta cttcagcgcg
    47761 gaatcaagac actaagtgtt cgtatggagg aacatcaaaa aaatgctttt gtggtagctg
    47821 attttctatt ttctcatcca gcagtagaaa aggtctacta tccaggatta cccgatcatg
    47881 aactccatgg agttgctaag cagcagatga gcggctttag cggaatgatt tcttttactt
    47941 taaaaaatga agaatctgct attccatttg ttgaatcact ccaactattt actttagcag
    48001 aaagtttagg tggcgtagaa agtttagtgg aaattccttc tgtcatgact catgcgtcta
    48061 ttccaaaaga aaaacgagaa gaggctggca taaaggacgg cttgatccgt ctttctgtag
    48121 gaattgagta tggtcaggat ctcataaacg atttagctca ggcatttgac agaatcaaga
    48181 actagaagtc ccaataaacg acttagcaga aaaatctaaa aaatatttca gattgctaca
    48241 ccttggaaac gataagtgtt agaatcaagt agaaagacgt ttttgtaaat ttcactaaat
    48301 aattctttag tgaaaagcat caaaacgaat gaacaaacag ataggagtct tacaaatgag
    48361 aatgaatgtc gaaagtttta atcttgacca tacaaaagtc aaagcacctt atgtacgtgt
    48421 agctgatcga aaaacgggtg cgcatggcga tgtcatcatt aaatacgacg tccgctttaa
    48481 acaaccaaat aaagaacaca tggacatgcc aagtctacat tcacttgagc acttgactgc
    48541 cgaactaatc cgcaatcacg cagattacat cgtagactgg tctccaatgg gatgccaaac
    48601 aggcttttac ttgactgtat tgaatcatga aagctacgaa gacattttag atgttcttga
    48661 agcaacaatg aaagatgttc ttgaagctac tgaagtacct gcaagcaatg aaacacaatg
    48721 tggctgggct gccagccata cactagaagg tgcacaagct ttggctcgtg aatttttagc
    48781 aaaacgcgat gaatggtctg aagtagaagc atagtttcta aaagaacgta aagatgagaa
    48841 gcaatatagc tatcttatct tcgtatttta ttaaatattt attgtctgaa aagagttcta
    48901 aacgggaaaa caaatagcta gttttcagtt tagcgctctt tttattatat aaaatagaaa
    48961 ggagaaaact ttatgtctat ttataatttt gaaactactt tagaagacgg cactgtctat
    49021 tcattgaaaa aatatgcagg caaaccgata atcattgtta acactgcaac aaaatgcggt
    49081 ctagcacctc aatttaaaca attagaagaa ctttaccaag cttatcagac acaaggtctg
    49141 gttatcttag gctttccttc caatcaattt aaacaagagc tagattcagc gactgaagca
    49201 gcagaagctt gtaaaaccac ttatggcgtt accttcccta tgcatcaatt gattgacgta
    49261 aatggagaaa atacagatcc tctttttact tatcttaaaa atgaagctcc tggtactgtc
    49321 actaaagcaa taaaatggaa ttttactaaa tttttgattg atagaaatgg caaagtaatc
    49381 gaacgatttg caccacaaac ttctccattg aaaatgaccg ctgcaattga atccgttctt
    49441 taacttaata aaaataaaaa aagatgaact atttctagtt catctttttg cctt
//
LOCUS       DAIGSZ010000016        48951 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.016, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000016 DAIGSZ010000000
VERSION     DAIGSZ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.016"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(324..1106)
                     /locus_tag="NOB31_000931"
     CDS             complement(324..1106)
                     /locus_tag="NOB31_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973158.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1171..2007)
                     /locus_tag="NOB31_000932"
     CDS             complement(1171..2007)
                     /locus_tag="NOB31_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0973159.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(2025..3434)
                     /locus_tag="NOB31_000933"
     CDS             complement(2025..3434)
                     /locus_tag="NOB31_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0973160.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILCSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(3448..5271)
                     /locus_tag="NOB31_000934"
     CDS             complement(3448..5271)
                     /locus_tag="NOB31_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0973161.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(6114..6440)
                     /locus_tag="NOB31_000935"
     CDS             complement(6114..6440)
                     /locus_tag="NOB31_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973162.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(6486..6848)
                     /locus_tag="NOB31_000936"
     CDS             complement(6486..6848)
                     /locus_tag="NOB31_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HCI0973163.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(6885..7099)
                     /locus_tag="NOB31_000937"
                     /pseudo
     CDS             complement(6885..7099)
                     /locus_tag="NOB31_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7227..7562
                     /locus_tag="NOB31_000938"
     CDS             7227..7562
                     /locus_tag="NOB31_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0973164.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(7638..9635)
                     /locus_tag="NOB31_000939"
     CDS             complement(7638..9635)
                     /locus_tag="NOB31_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973165.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(9733..10008)
                     /locus_tag="NOB31_000940"
     CDS             complement(9733..10008)
                     /locus_tag="NOB31_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973166.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            10240..10974
                     /locus_tag="NOB31_000941"
     CDS             10240..10974
                     /locus_tag="NOB31_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0973167.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            11013..12155
                     /locus_tag="NOB31_000942"
     CDS             11013..12155
                     /locus_tag="NOB31_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0973168.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(12250..13641)
                     /gene="sufB"
                     /locus_tag="NOB31_000943"
     CDS             complement(12250..13641)
                     /gene="sufB"
                     /locus_tag="NOB31_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HCI0973169.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(13646..14116)
                     /locus_tag="NOB31_000944"
     CDS             complement(13646..14116)
                     /locus_tag="NOB31_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HCI0973170.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(14103..15338)
                     /locus_tag="NOB31_000945"
     CDS             complement(14103..15338)
                     /locus_tag="NOB31_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI0973171.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(15335..16621)
                     /gene="sufD"
                     /locus_tag="NOB31_000946"
     CDS             complement(15335..16621)
                     /gene="sufD"
                     /locus_tag="NOB31_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HCI0973172.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(16634..17407)
                     /gene="sufC"
                     /locus_tag="NOB31_000947"
     CDS             complement(16634..17407)
                     /gene="sufC"
                     /locus_tag="NOB31_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HCI0973173.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(17604..18452)
                     /locus_tag="NOB31_000948"
     CDS             complement(17604..18452)
                     /locus_tag="NOB31_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCI0973174.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(18476..19162)
                     /locus_tag="NOB31_000949"
     CDS             complement(18476..19162)
                     /locus_tag="NOB31_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973175.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(19155..20189)
                     /locus_tag="NOB31_000950"
     CDS             complement(19155..20189)
                     /locus_tag="NOB31_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0973176.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(20252..20508)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(20584..20922)
                     /locus_tag="NOB31_000951"
     CDS             complement(20584..20922)
                     /locus_tag="NOB31_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HCI0973177.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(20924..21280)
                     /locus_tag="NOB31_000952"
     CDS             complement(20924..21280)
                     /locus_tag="NOB31_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HCI0973178.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(21286..22473)
                     /locus_tag="NOB31_000953"
     CDS             complement(21286..22473)
                     /locus_tag="NOB31_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCI0973179.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(22664..23509)
                     /locus_tag="NOB31_000954"
     CDS             complement(22664..23509)
                     /locus_tag="NOB31_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0973180.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     HLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTKRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            23743..24708
                     /locus_tag="NOB31_000955"
     CDS             23743..24708
                     /locus_tag="NOB31_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HCI0973181.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            25085..26128
                     /locus_tag="NOB31_000956"
     CDS             25085..26128
                     /locus_tag="NOB31_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HCI0973182.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(26190..26654)
                     /locus_tag="NOB31_000957"
     CDS             complement(26190..26654)
                     /locus_tag="NOB31_000957"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HCI0973183.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            26900..27847
                     /locus_tag="NOB31_000958"
     CDS             26900..27847
                     /locus_tag="NOB31_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0973184.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(28058..30130)
                     /locus_tag="NOB31_000959"
     CDS             complement(28058..30130)
                     /locus_tag="NOB31_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCI0973185.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(30063..30440)
                     /locus_tag="NOB31_000960"
     CDS             complement(30063..30440)
                     /locus_tag="NOB31_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HCI0973186.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(30569..31147)
                     /locus_tag="NOB31_000961"
     CDS             complement(30569..31147)
                     /locus_tag="NOB31_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0973187.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            31279..32571
                     /locus_tag="NOB31_000962"
     CDS             31279..32571
                     /locus_tag="NOB31_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI0973188.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(32631..33749)
                     /locus_tag="NOB31_000963"
     CDS             complement(32631..33749)
                     /locus_tag="NOB31_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HCI0973189.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(33763..35184)
                     /gene="arcD"
                     /locus_tag="NOB31_000964"
     CDS             complement(33763..35184)
                     /gene="arcD"
                     /locus_tag="NOB31_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HCI0973190.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(35430..36551)
                     /gene="mnmA"
                     /locus_tag="NOB31_000965"
     CDS             complement(35430..36551)
                     /gene="mnmA"
                     /locus_tag="NOB31_000965"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HCI0973191.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            36955..37554
                     /locus_tag="NOB31_000966"
     CDS             36955..37554
                     /locus_tag="NOB31_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HCI0973192.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(37692..38978)
                     /gene="efmA"
                     /locus_tag="NOB31_000967"
     CDS             complement(37692..38978)
                     /gene="efmA"
                     /locus_tag="NOB31_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HCI0973193.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(39249..39593)
                     /locus_tag="NOB31_000968"
     CDS             complement(39249..39593)
                     /locus_tag="NOB31_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HCI0973194.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(39730..40875)
                     /locus_tag="NOB31_000969"
     CDS             complement(39730..40875)
                     /locus_tag="NOB31_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI0973195.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(41055..42029)
                     /locus_tag="NOB31_000970"
     CDS             complement(41055..42029)
                     /locus_tag="NOB31_000970"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCI0973196.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(42109..42984)
                     /locus_tag="NOB31_000971"
     CDS             complement(42109..42984)
                     /locus_tag="NOB31_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HCI0973197.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            43114..45021
                     /locus_tag="NOB31_000972"
     CDS             43114..45021
                     /locus_tag="NOB31_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HCI0973198.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(45562..48840)
                     /locus_tag="NOB31_000973"
     CDS             complement(45562..48840)
                     /locus_tag="NOB31_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HCI0973199.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
BASE COUNT        14046 a        10299 c         8640 g        15966 t
ORIGIN      
        1 gttatcttta gaaccatttc agatacatat gaaacaatta catatgattt tttcataaaa
       61 aaacagtact gtctagtagt ataaaatata caaatttctt aaaaattttt tcactaaaat
      121 cactacctga aacagtctaa aacacttata tatcaacgtt taatgaaact atctccgttt
      181 catttcagat acaaataaat atagtcgggc tccaaatccg aaaaaaaata cccccagtag
      241 cttatcctaa gctactggag atgtataagt acggtcatat aacaacgggg tagggtaaat
      301 aaatgaaaaa gatggaagaa tcattattca ataacttttt taaatacttc gttgtaatca
      361 gttacctgtc cgttcttaaa taccacagaa taatcttttt tcccattttc aagtaaccga
      421 agtggaatgt ctttaccaac ttgctctgtc actgcattac tgatacctgt tagattagct
      481 aataaatctg ataaagattg agcatctgta gaaatctctg tatcagtatt tatcgtgatt
      541 cctttatctt catttacaag cttccaagta ggtggtatag ctgtgtatgt ttcgatgaat
      601 gaatcaattc tttcatctat cgtcttccca gtatctactt ctgtctcatt actcttagat
      661 gaatcgattc tttcatccat cgtctgctcc gtaactgctt ctgtctcatt attctcaccg
      721 gaaactctct tcacacccaa acttatatat tgtccatctt tagtgtgcat agttaaaatt
      781 cccacgcttt tactaataaa ttcactataa ccagttcttt caatagagac ttcaatgtat
      841 ttcacactat catactcaaa agaaaaatag acatgtaaaa gcattttgtt gtttacatct
      901 acataataat cctttgactc tacttgagac cttcctatac ggaatacagc tttactgtct
      961 gatatctcta taccagcatc cttattatta atctgccaat ctccaagtag ctcttctggc
     1021 aagctagtag tttcttgtga acactttacc acttcactgg tagaggtcga aacattcacc
     1081 tccgcactgt tagaagaatt ttccaaggaa tcaggagcct tagcacaacc aacaagtctt
     1141 tatatattgt gcagccgata ttttcttcat tcagtacacc cttgaaatat gcagtgttag
     1201 ataaagcagt tcgtcctgat ttgctgaggc acccatctct tcttgaacgt actccttgat
     1261 tttcaaggcc gcccgatact ctttcggaaa acgctgcttc actgaagcca gcaaaaaatc
     1321 atccttctcc ggcaactctt ccttcttaat cattcgggca ataaaaaact gtaaatgcgt
     1381 cacaaatctt aagtaaagca tcgaatcttt atcaaccttt ttttcgggaa acagatatcc
     1441 tagcatagcc aagatatcct ttagtgctct taccgagagc atggtttctt ccatatttgc
     1501 ttgttcactt tgggcattta caatgtgaaa cgcaatgttt ccagcctcct cttctggcaa
     1561 ctgaacattc atttttttgt tgatcaattg gatagcatag cagccgatct caaattcttt
     1621 tgggtaatac ttttgaattt caatcagcag gcgattttga aaaacaatgc ctttttgact
     1681 gcgttcaatg gcatgcttca agtgatcaac caaggtaaaa aatagacttt tattcagctt
     1741 aaagtcaaac ttggcgttgg cataatcgat aattcgcttg acgcaaataa ttagatcatc
     1801 cggagcagcc tcaaacagtt taatgtaatc cttttttaga gcatcagaaa gtgaatctaa
     1861 tttaaatact ttttggattt tgtcagccgg aaccaaatcg cctttcttta gttgaaatcc
     1921 aatccctttc cccatcaaaa ttacttcttt gccttgctta tctaagcaaa gaattaaact
     1981 gttgtttaac gttttaatta ctctcattag attcaccgtt ctctctaagc taagccattt
     2041 cttgcgatta ctttttgata ccaaaagaag ctttcttttt ttattcgttt taattcttta
     2101 agattctcat cggttcggtc aacatatata aaaccataac gcttattgaa gccttgatgg
     2161 gtactaacaa catcaatcgc tgaccaaggt aaataaccaa aaacatctac accatctgtt
     2221 aaagctgctt gaatagccag aatatgtttg gctagataat caattcgatc ctggtcatta
     2281 attcgtctat cttcctcaac tatgtcgggt gccccatagc cattttcagt aattaaaata
     2341 ggtaaatcat agcgatcgta caatttcctc aatgttaatc gtagtccagt agggtcaact
     2401 acccagccat atggcgtttt atctacataa ggattttcag ctgcccggta gacaccttct
     2461 tctcccaaca tgatctgttg atcccccgct ctagcggaaa catctgatcc gtcatttttg
     2521 ctggcagcga tggtggcagt tgaataataa ttaatcgcaa taaaatcggg tttaccggag
     2581 cataaaattg cctgatcctc tgcctcaatt ttaggatata atccacgatc attcaaatag
     2641 ttttcaaaca aataattgta ttttccccga actgctacat ctaagaaaga ccagcctctc
     2701 aatgtttccc aattatgggc tgcaattgca tcttctggac tggaggtagc ttgatacata
     2761 gccgttaaat tgattgctgg accgattttt cctttaagat tcaactgatg atacaagtga
     2821 attactctag cttgagctaa taaaacatgg tgattaattt gaaagagttc tttttttgaa
     2881 ggcagctctc cacttggtgg caaaccaatc gctccaggat gaaggatcat cgtgttttgc
     2941 tcattaattg tcagccaata gttcaccttg tcaccatact cagtaagcaa tacctgtaca
     3001 tagtccacaa aataatcgat agttgctcga tttaaccaac cgccctgctc ctctagaaaa
     3061 taaggtaaat cgaaatggta catggtgaca atcggttcga ttccctgatt caggcattca
     3121 tcaattactt gatgataaaa agaaattccc ttttgattgg ttttattatt ttcaatatcc
     3181 ataattcgcg tccaagcgat ggaaaagcga aaagctttta agcctaattc tttaaacagc
     3241 tgtatatctt ctttatagtg atggtaaaaa tccgaggcaa cttcaaaatt agctacccct
     3301 tctgtatgct gatacttgtc aataatagac ggttgtttcc catcctcctg ataggcaccc
     3361 tctgcctggt aggcactaat ggaggcaccc cataaaaact tctctggaaa tgctgaaagc
     3421 tgtttgtatt gcacaaaaat cctctcctta actaatttgc atcaatggtt cgtgttcctt
     3481 taagcttccg cttgcttcac taattcctgc gtaattttca ctgttggtca ctaccacaat
     3541 cactgtatca tcgtagccag cgtttctaat ggcagcgaaa tcggcgttga ttaataattg
     3601 tcctgctgac acctgatctc ctgcttttac aaatacttca aagggttccc cttttaaatt
     3661 cacggtgtcg atccccacat ggatcaataa ttcaatacct tctttagaac gtagaccaat
     3721 cgcatgttta gattctaaaa tagtaatgac ttctccctca acaggtgaat aaatgctgtt
     3781 ttcttctgga tgaatggcta cgccctttcc caatagtccc ttagaaaaga cagcatcgtt
     3841 cacttcagaa ataggacaca cggttccttt taccggattt tcaacaatga ctgcttcggc
     3901 tattgccgtt tgctctgatt catcagaagt atcgtcaaat ccaattagat aagcaatgat
     3961 aaaggttgca acaaaggcga ttacacacgt aataattgcg tgaacaatat tcattggatt
     4021 ttctccaata aaggctggta aggctgctaa gccaggggaa acaaaggcat atctgactaa
     4081 accgctcaag ccagcataca aaccagcaat tgcaccacca atcatggaag caactaatgg
     4141 ttttttcagc ttcaaggtta ctccatagag tgaaggctca gtaattccca ttaaagcagt
     4201 gatcccagtg gacacagcta gctgcttcaa ctctttgttt ttagttttcg cggctacagc
     4261 aaaggtagca cctgattgag caatattaga agccagcatt cctggcccat tgatcatttc
     4321 agaacccgta ctgctcaatt gcatagtagc gattggcgtc attgcccaag ctgtacccgt
     4381 aaccaccaaa aatggctgca aaccacccat caaaaatgga attaaccaag ctgctttgcc
     4441 gttaatccat tcagccccca ttgctataag atcgttcagc aacgttccaa acggtccaat
     4501 gacaaccaac gctaaaggcc ccataattaa aaataccagc atcggcttag taaagaattt
     4561 aataaacgaa ggcgaaattc gatccgcaaa gggctctaca taggacatga tccaaacagt
     4621 aaagataatc ggtaaaactg atcccgcata atctgcagct aataccggaa ttcctagaaa
     4681 agaaacggca tcgccagtag aaaaaagctg tgaaatattt ggatgaagca aaatgccagc
     4741 aacagtaatc gccaaaattg ggttgacatc aaactttatg gctgccccat aggctaatag
     4801 tactggcata aaataaaagg ctgcatcagc aatagtattc aaaatgatgt aagtttgact
     4861 actgtctgat agtacaccag tcaaagtcaa gacggccaaa atggctttta ccatcccggc
     4921 acctgttata gctggaatca tcggtgtaaa ggtggtagaa atgacactaa tcaatcttga
     4981 aataatactt tcttgattgt ctgaagaggg gcccttttta attgaagttc ccacttcctt
     5041 ttgaatttcc ttgaaggctg tttggacttc attgccaatc accacttggt attgtccacc
     5101 gctatccacc acactaatta caccaagtgt tttttctaag gctttcgtat cggctttcct
     5161 tttatctttg agttcaaaac gcagtctggt ggcacaatgg gttaagctga ccacattttc
     5221 ttttccccca acctgttgca atacatttct tcctacttct ctgtaatcca ttattctctc
     5281 tccttaaagc agtaaaaaag accaagtcaa accacgcccc aatcaacatt gaagtgttag
     5341 tttgtcttgg tcttgcctgc ataatcagta acatgccaat aacgttattt tgctgtaatc
     5401 caataatagc acattatgat agcgcaatca acagggaatt taatttttta tcttttcgtt
     5461 tgaccgtata gggtaatata acagttagat cacatcaact agggtatatc tgcgtatact
     5521 tactgctaaa ataagtatat ctaatattaa ctataccagt aaaaccattc ctacataacc
     5581 agcgggaaat tcccaaaatc gtgaaagcat caaaaatgca tataacggat cacacaactt
     5641 caacaattct gctcttggga aaaattgatg aatttggtga gtaaaggatg gaataaacag
     5701 cattccaaca atataggcaa caatagtgat acttgttttt ttggtaaaaa tcagtaagca
     5761 atagccaatt tcaatcattc cgagatataa aggtatcgat agaatgattt gggctagtat
     5821 tcttaaaaat taactagcaa atgtttaaac tgatttattt ctaatctaca tgtagtaagt
     5881 atttcaattc caccaattat caataaaaat accaaacata tccataataa ttttttcttt
     5941 ttcatttctt ttatattgtt ataacagtga ataacataaa aattcccgac aatcattgta
     6001 atattttttt gtcacctgta ttagtattta atttatagga aactataaaa actccctagt
     6061 gaatttacac ctttgggagt tcctgtttgg acggtatgca taatacattt aaatcaattt
     6121 aacattaaca cctcagcata tggtatctcc acatatatac ggtctttctt tggatagtac
     6181 tcaatattta tgttgatagc acttccattg tctaatatag ctttagcccg gtatgtgtta
     6241 tctccatttt catgagtaat cgtcacatca tcacatgatc gatttaagtt gtactgttct
     6301 tgtaaaatct gtgttaccaa tggtttcgat gacttctcta atccagatgt acctgtcatt
     6361 tttgaaaaaa tgatacctat aatagccaag acaacgataa ctataatgat aaacttcttg
     6421 ttcatattta ctttattcaa ctttttatct cctatctcca aaataatttg ctcttatccc
     6481 tcttatcagt acattgacat ccctaaaagt acaccaaaga ttgctccagc tacccctgct
     6541 atcatcaaaa tcgtacccat ttgttcatct ttatctcgat ataagtagcc cataataaca
     6601 gcaacagcac caaatacaac aggaataaat gctaacgcta ctaccataga aatccaacca
     6661 ataatcaaat acagcttccc tgtctcttgt ccatgtacga tttgttcctt catttcatta
     6721 attgtctgct cagtactttt ctttactgcg tctgctccag ttgtctcatc tgtttcttgt
     6781 agtgctccgc aaaactggca atacttactt tcatctgtta tttctttgcc acattttcta
     6841 caatacatgt cttctcctcc taaaaacatt caattgttta ttagttaact gtttacttta
     6901 ttaaatacat cagaaaacag ctcattcatt ggtacactta atatctcaga aagcatcttc
     6961 atttgatagg gtttaggaat cgttctccct gtttgccacg aacttacaca ttgctgtgta
     7021 acattcattt ttttgctaac tccgtttgag aaagtccttt ttcttttctg tatcggctga
     7081 gattacttac ttttttcatg attctcccct cctgttttat tatatacaac aatatgatgt
     7141 atttcaactc ataaaatata aaaaaacttc aaataccatt acaaatacaa caacttgttg
     7201 tactatactg agatgggggt gtattaatga aacagaaaca atatgcaaag gtcattagag
     7261 aaaagcgaaa agctctcggg tggacacaaa aagaattagc tgaaaaaatc ttctctacac
     7321 aacaggcagt agcaagatgg gaaaattctg taacagagcc taacctcgat agcttaaccg
     7381 ctctttctag agccctagga acccctgtaa gccattttct agacaatgtt gtcgtagatt
     7441 atgaggaaga gtttttggct ctctatcgtt ctcttagcac tgaagatgca gttcgaacaa
     7501 ttgactatat gaagctatta aaaaggcaag aaaatgaacg caatcagcta ttgaaagatt
     7561 gaaaaataaa taacccaccg aactttaacg gtgggtgtat tgagatgaaa taagattaag
     7621 agctatggat aacctgtcta gtttaataca attgggtctt ttctcttcct tactctccgt
     7681 ccatcatctc ttgttacact tgtaaattga taaagaggaa ctaattcaac tcctgataat
     7741 atcaattctt ttattacttc atctatccct gctccttttg ctaggtagac taaaaaacta
     7801 ctacttgctt tcacattgta tagtctctta atatccttag aagctcgttc aagagtgaat
     7861 ccttgtttaa caaagtagcc tctgttttct tttaaagcat tttccacgct gttattccca
     7921 acattacgta gacgttcaca aacagtgtta gtaagttctt tctctgtcat tagatatgtt
     7981 ccttgccacg ataagccctg taaaacttca tgtgcttcat ctaaaatcaa ttgtttttcc
     8041 ttgctaagtt ctgatcggga attttgagga aatactcttt tagcctcttt ttcgttaaaa
     8101 catatcttaa cccattcata agaaaaatat tgatatgtaa aatgaaattt ttccagaagt
     8161 ggaaggatat cttcattcaa tttttgaatc acagaagttg cattaaaaac gtctaatcga
     8221 tagacattgc ttctcttatg attaaagttt cctaacgctt tctcttcctt taacctattt
     8281 aggtattcga gcatcttcaa aggaacatct tcatcatcta atttttttat caatcctata
     8341 aaagtcataa gtgatagtaa cttattacat ttatctatgt cataagtttt accatagtaa
     8401 aaactcattt ttttagctaa ttgttccccc gacaaaatac aagtcacact ttccttacta
     8461 tcatcaaaaa aattaacatc agaaagcaag acatcataga cacgtcgcat ttcctctaga
     8521 taattcctta ttgtcctgaa aagtttgtct ttcattgatt caagagtgtc aaaaagtact
     8581 tttgattcct ctttcaattt tcgaaaatgt gtaggataca agtctaggtt ctctaatagc
     8641 caattaaatg tttctacccg actgtctttc tttaaaatta gcatcacaac tccaataaaa
     8701 ttttcactga tatcacaatt actggaatga caataaaaaa tggaatgccc agttttactg
     8761 gtaaaaatac tagcagaggg attatgatcg ttgtgaaaca gacatcttaa gtttttactt
     8821 gacttaagta atttattcat atcaatggtt aacaatcttt cataaatctc attaaaagac
     8881 atgtcggagg aatcaaacag gcagtcttta aaccactgtt tcatttcttc tttgtcgtca
     8941 ttttttatca acttaacaaa atcggtttca ttgactagtt catactctct ccctgaatca
     9001 ctttgacaat ttttagaaca tgtcatggta aaatcaatcg gaagctcagt aatatctaac
     9061 atgttgtctt cattaattat tatcactgca tctgacttat atcctccaaa aaacattcta
     9121 ttcgaagcat ttacattgtc atcacacccg gggatgttct ttttcaagta ttcgtaaaca
     9181 gcaaccattt taccatagtc agtaattgct tcttttaata gaaagacaat cttgtatttt
     9241 tctagatttt cagagtaccg aatacttttt tgtatcgcaa acgcagaatt atgaactaaa
     9301 ttgatagata aaaccttttc tatgcttaag tatctactat catctttact caaatctact
     9361 accttcccct tctcatcttt aacagtgtta tcgacatcca gaataattac tctggtttcc
     9421 acaaaactct ccttgtcatt gcctttattc tttgtcttgc ttggaataaa tgattgtgat
     9481 gaatttagta tctctacaaa ctcatctctt gtaacttctc tatagttatc taaacaccta
     9541 tctcttacat cagttttttc tttttttgta actggcttct ctaataattt ttctttatct
     9601 acataaattg gaatattaat cattgatgtt tccatttgtg tttcctcctt ataaaattct
     9661 gttaaagact aaaacataca gataataaaa acaaactctt tattactata tgttttagtc
     9721 ttatttgttt actcaacctt tataccgttc catgaaacta tcaatatcag attttttaaa
     9781 tctaatgacc gtatcaattt ttataacagg taacccgtat tgagaaacat attttctaat
     9841 cgttcctact gatacaccta gatattcact tgcctgctga tagtccatat actctagagt
     9901 gactccagaa ataatgtctt ctagcatagg ctttagcact gtaattatct ctttcacttg
     9961 ttgttcaact tgtatagaaa caatgctatc aatgatttgt agagacatat ttccccctcc
    10021 tttcgtgatt gcttgaacaa attttctaag aattatcttc gtattttttg ctcaaaataa
    10081 aagtattttg ttattaaccg attaatcaaa caaaaaatga ttaccagttc atcgacatac
    10141 acataatacc tcgataaaaa agaggtgtca atatctttgt aaaatttatt tacaacaccc
    10201 ctttttcgag gtatactaat tttaggaggt gtggtcaata tgataaaacg tccaccaata
    10261 aattatttag aacgaaaaaa gatactcgga acaaaaataa aagctataag aaagagtaaa
    10321 aaattaacac aaccagcatt tggtcttatg attaacaacg gtcaattaat tgacaaaaaa
    10381 actatctacg aatgggagaa gggaacctat ttaccaatac cagagcgatt atcccgaatt
    10441 gctgatttgg gaaatatgag tatagaggag ttagtttgtg gcaatgtaga agaatatatt
    10501 ttgggaatta ttctttatag agatagcatt gtactagatg gtataacatt tccagataaa
    10561 aacctgttcc agcatcttcg tcaacagttc ccaccagtac actctaattt agatacatgg
    10621 ctggatagat attccaaatt agaaccagag atgcaagaat ttattgctaa caagacttgt
    10681 aataaagtta aaaatgaaaa aattagtctt ttcaatatct taaaaataga agaattattc
    10741 atcaatgcta ttgtagaaga atttgacaat aacattcttt tcctcactag cagtatagaa
    10801 gaactactag aaagaatggt agatgaatgg ctacctattc aattgaaaga catgtcttat
    10861 cccgaagaag ctgtgagaga aattactgat aatataaaca agctagaaca aacgatttca
    10921 tcaattggga aaaaatacac taagaaaaaa atgaagggag gtgataccat ctagtggtaa
    10981 gtactccttg taaactaaga ggagatgatt tcatggcaaa aatatcaaag tacaaaaaga
    11041 aaaacggtca agtggcgtgg atgtataaag gacacattgc caccgatcca cgaactggtg
    11101 aaaaaataaa tactacgaga agaggtttta gtagcaaaca agaagctcaa aaagattatg
    11161 acgagtacag acatcaaata ttatacggtg ttaaaaagaa agcacctgat atgacatttg
    11221 aagacctgta taatgaatgg ataactcatc agcgtaccag tgttaaagct tcaacaatcg
    11281 caatctcagt aagatacgca aataatcaaa tacttccagc atttggtaag cttaaactat
    11341 cgaatatctc tgtcccatat tgtcaaaaag tggtagatga atggcacagt aaatatgaaa
    11401 gttacgatta tatgagaaaa cagactgcac aaattttacg ctacggggtt gcaatgcaat
    11461 atattgacaa taatcctatg gaaaaaacac ttcttccacg aaaaaaagag tatgagaaaa
    11521 atcgtaaatt ttactcaaaa gaggagctta ataatttact ggatgctttt aaagattttg
    11581 gtaacatgaa acaatacgcc ttcttcagat tattggcata cacaggtatg agaaagagtg
    11641 aagtactcgc tttacagtgg aaagacatag acacgtttaa taaagaacta catgtcaata
    11701 aaactcttgc tgtagatgaa tttggtaaag ttataattca atctccgaaa acaagagctt
    11761 ctagacgagt tatctcttta gatactgaga ctctttctat cctcaacaac tggaaattac
    11821 agcaaaaaga agagtattta aaacttggat acaatactag ctctaaagag caacatgttt
    11881 ttacaacagt taaaaacact ctatacattc caaacactgt taatgattgg ttaagatata
    11941 ttttgaaaaa atataacttg cctcgtatta cacctcatgg gtttagacat acacatgcta
    12001 gtttattatt agaagcagga gaatctgtca aggtagttca acaacgatta gggcatgaaa
    12061 atagtaaagt gacattagac atctatgcac atattacaaa taatgcacct aagaaaacag
    12121 gtcaagactt tgctgatatg atggctcatc agtaaaagag ctggtcaaaa tctggtcatt
    12181 tctagtatac aggcaaaaca aaaaagctag aacccttata tatcaagggt tctagctcct
    12241 ataacaggtt tacccaacac tgccttccat ctcataactg atcaatcgat tgagttcgac
    12301 tgcatattcc attggaagtt ctttggtgaa tggttcaaca aagcccatga cgatcatttc
    12361 agttgcttca gattcggtca ggcctcggct catcagatag tagagttgtt cttctgagat
    12421 ttttgagact ttggcttcgt gttctaaaga gacttggctg ttgtggatct cattgaatgg
    12481 gatcgtatcg gatttcgacc attcgtccat gatgatcgtg tcacattcga tatgagagat
    12541 cgaacccgca ctgtttttgg caaaggttac ttgtcctcga tagtttactt ctccgccgtc
    12601 ttttgaaatt gatttagaga cgatagagct agatgtattt ggtgcattgt ggatcatttt
    12661 tgcacccgta tcttggattt ggtttgctcc tgcaaaggcg atggagagca tggtgcctcg
    12721 tgcacctttt ccatctaagt aaacacttgg gtatttcatc gttgtttttg cacctaggtt
    12781 tccgtcgatc cattcaacgg ttgcgccttc gtatgctttt gctcgtttgg ttactaagtt
    12841 gtacacattg tctgaccagt tttggatcgt tgtgtaacgg caatacgcat cttttcttgt
    12901 aaagatttct acgatggcgg catgcaggct gttacttgaa taagtaggtg ccgtacaacc
    12961 ttcgacatag tggatgcttg ctccttcgtc aacaatgatc agcgtacgtt cgaattgccc
    13021 cgtgttttcc gcattgatcc ggaagtacgt ttgtaatgga acatcgactt tgacgccttt
    13081 tggcacgtaa ataaaggtcc cacctgacca tacggctgaa ttcagcgctg ctaatttgtt
    13141 gtcggttggc ggtacaagtt ttgaaaagta ctctttgaat aattcagggt attctttcaa
    13201 agcagagtca gtgtcagtaa agacgattcc taacttttcg aattcatctt tcatattatg
    13261 gtacacgact tctgattcat attgtgcgga agcaccggct agataagctc gttcagcttc
    13321 tggtatacca atcttttcaa atgtatcttt gattttttct ggtacgtctt cccagtcacg
    13381 agcgggtttg tcacttggtt tttggtaata tttgatggca tcgaaatcga tgtctgaaag
    13441 gtcggggccc catgtttgca ttggcatttt gttaaatgtt tctagagatt tcagacggaa
    13501 ttcaagcatc cattctggtt cgcctttgat tcttgacatc tcacggatca cttcttctgt
    13561 caagccttct cctgtactga aaaccggttc gacatcatcg tgaaacccga atttatattc
    13621 ttctaattct ggtacgccca tgttctcact cctcttcctt gtggtaatga tggaaagctg
    13681 cggtaccatc gttttccatt gcttttccta gtgctttcca ggcaagtgtc gcacatttga
    13741 tccgagcggg aaatttagct acaccaccaa gcatagcagc atcgcctaat tggtcgggat
    13801 ctttgacttc ttttccttgg acaagctgta gaaagtctac agttaaatgt tctgcttctt
    13861 ctattgattt tccgatgacg gcgtctgtca tcatcgaggc acttgccgta ctgatggagc
    13921 agccactgcc gtcaaaggcg atatttttga tgattccgtc ttttacatcg acttgcaatt
    13981 cgatcacatc tccacatgtg gggttgttca attcgatctt gcttgtcgag tcagtcaagc
    14041 ttccacgatg atgcggatgg gaagaatgat ccaagatcac ttgacggtat aaattgtcta
    14101 atttagatag tcccatgttg gaaaaactcc tttgttgcca tgattgcttc aactaaacgg
    14161 tcggcgtctt gcgttgtgtt gtagaaataa aagctcgcgc gagcagtcgc tgatacttca
    14221 aggtacttca atagcggttg cgcacaatga tgacctgctc tgacggctac cccttccatg
    14281 tctaaagctg tcgcgacatc atggggatgt aacccatcca aattgaatgc aacgactcct
    14341 gtccgaaaat tcgggtcttg tggaccataa acagtcaatc catcaattgc ttgtaatttt
    14401 ggcaacacat aagcggctag ttcttcttca tatcgatgga tattgtccat accgagtttt
    14461 tgcaaataat cgattgcatg gcctaatgcg atagcgccgg cgatatttgg tgtccctgct
    14521 tcgaatttcc aaggtagttc tttccatgta ctgtcgtata attcgacaaa atcgatcatt
    14581 tcgccaccaa attcaacagg ttccatttct tctaaccatt ttcgtttacc atataaaaca
    14641 ccaatacctg ttggtccgca cattttgtgt ccgctgaaag caaagaaatc acagtctagt
    14701 gcttggacat caatggccat gtgcggggca gattgagcac catctactac gatgaccccg
    14761 ccgttttcat ggacaagttc agctaattct tgaacaggat tgaagacacc taagacattg
    14821 gatacatgag caatggagac gattttggtt ttgtccgtaa tctttttcgc tgcatcctcc
    14881 atatccagga agccttcttc tgttagttcg atatatttca agacagcacc tgttcgtttt
    14941 gccaactgct gccacgggat aacattagaa tgatgttcca tgtaagagag cactatctcg
    15001 tctcctgctt tgatatagcg gtcgccgaag gttctggcta cccaattcaa gcttgtcgtc
    15061 gtaccacgag taaacagcac ttctgctgtt tcttttgcat ggatgaacgc ccgtactttt
    15121 tctcttgctt gttcataatc atgggtcgcg cgttctgcta acgtatggac accgcgatga
    15181 acattggcgt tatcgtgttc gtaatagtac gctaatgcct ggagtacttg ttttggcttt
    15241 tgggtcgtcg ctgcattatc cagataaact aaaggttcat cattgacgtc ttgaaataag
    15301 ataggaaaat cattgcgtag ctttttagca tcgatcatcc attcaacttc ccttcgatta
    15361 cttcgactaa ttctttccga acttgttcta cagggattgc tgttaagaca gaaccgagga
    15421 atcctcgaat cactaagcgc tctgcttctt ctttatgcaa tcctctactc atcagatagt
    15481 acatttcttc tggatcaact cgtcctacac tggcagcatg tccagcagtt acttcgtttt
    15541 catcgatcaa aagaatagga ttcgcatcac cacgtgcttt atcagaaagc atcaagacac
    15601 gactttcttg ttgggcatct gcaccttttg cccctttcaa gatgtggccg ataccattaa
    15661 aggtcaatgt tcctttttct cggatcactc cgtgttgcaa aatatgcccg atcgtatgag
    15721 gggctttatt ggttactcgt gtatcgattc cttggatttg tctgcccgag ctgattgcca
    15781 cgattttgac ttctgcgtgt gcaccttctc ctgctaaatc tgagtcaaag tcagcgatca
    15841 catgaccgtc attcatgaca ccaattgccc agtcgacaga agcatctcgt aaaatgtgcc
    15901 cacggcgatt catataagaa gtaatatttt ctcctaattg atctacggct gaatatttga
    15961 tttttgaacc agctttagcg atgacttcca cgatgatatt acctgatgat tttgctactt
    16021 gttctttggt tgtctggaaa cgttccagat aagaaaattc actatgttca tctgccacga
    16081 tcaacacatg cttgaagaag tgctcatcgg atgcgccatc ttgaatgaat aaggactcga
    16141 gtggttcatc gatcacgaca tttttaggca catacaggaa aataccgctg ttcataaaag
    16201 ctacatggag tgcagtcaat tggtcttcgt tcatgtttac tgcttttttc atataatatt
    16261 cttggactag ttctggatat tcgatcattg cagtgaacaa gtcggtaaaa atgactcctt
    16321 tttctgctaa ttccacaggc agttgttcaa aaatcgtcca tgaaccttgt tggacaagca
    16381 caggattgtc tttcattgca tcaaatgccg gaatcgtgcc tgtttcactg atggtttgtg
    16441 tttctttcac atcaaataac gaccagcgat ggaatttcac ccgatcgata tgcggcaatg
    16501 gcagttcatc tgctttcgct agtgcgtctt gacggaaggt tctcatccaa tcaggttcgc
    16561 ctttacttaa agaaaaatca tttaccgcgt caagataatc gagccagttt ttttctttca
    16621 ttcttgctcc cccttacgct tcttcttctt tatagtcgat tcctaattct ttactgatac
    16681 cagcgtagcc ttctgcttcc agacgtttag ctaggtcagc attccctgtc atgactactc
    16741 ggccttccat catgatgtga acgacatcag gtgtgatata gttcaataat cgttgatagt
    16801 gggtgatgat caatgcaccg aaattgtctc cgcgcatttc atttactcct ttagcaacga
    16861 ctttcaaagc atcgatatcc agacctgaat cgatttcgtc taaaattgca aatgtaggtt
    16921 ctaacatcaa caattgcagg atctcattcc gtttcttttc tccgccagaa aaaccttcgt
    16981 tcagataacg ttcagccatt tcttctggca tatttagtaa agccattttt tcatctaact
    17041 ttttcaaaaa tgccataaca gaaattttgt cgttttcatc acgtttcgca ttgatcgctg
    17101 cacgcatgaa ttccgcattc gtgatacctg gtatctcact tggatattgc atagctaaaa
    17161 ataagccaag tcgcgcacgt tcatctactt ccaagtctaa aacatttttc ccgtcaaaca
    17221 aaatttcgcc ttctgttact tcatagtttg gattgcccat gatagcggca gataaggtag
    17281 attttcctgt gccgttaggt cccatgatgg catggatttc tccggttttc attgttaggt
    17341 ttacgccttt aaggatttct ttttcctcga tcgacacatg tagatttttt atttctaaga
    17401 cagacatgca ttataccccc aaattctctt tcgttctcac tcattttaga ctaattgaga
    17461 atgaagcgca atgaccttcc ttactaaaat caaatatctt ttatttatta ttaaacaatt
    17521 ttgatttcta aattagaata ggtataaaaa agatgagaaa taagccatta cagacttatt
    17581 tctcatcttt tttgttccat accttatttt gcatcagcct ttactggttt aacagagccg
    17641 ccccatttgt ctgtgatcca ttcttggact tctttgcggt gaagcacttc aatcagtttt
    17701 ttgattttgt cactgtcttc atcaccttta cgagtcgcaa taatattcac gtaaggagag
    17761 ttgtcctttt caagcaatac ggcatcttct aatggattca accctgcgcc gtaagcgaag
    17821 tttgcgttga ttgcaactag gtcaccttca tcattttggt acgtagaagc taaaagtgat
    17881 gggtcgatcg tatggttgaa cttcaagttc ttagggtttt cttcaatatc atcgaatgtt
    17941 gctgtttcca gatctactcc atctttgact ttgactaagc cagcatcttg tagaattgtg
    18001 atgatgcgtc cccagtctga ttcagaattt gaagtaatga ttgttgcacc atcttttaat
    18061 tcggaaacat ctttgacttt tttagagtac aagcccattg gttcgatgtg gacagcaccg
    18121 gcattgacaa agtcatatcc tttttctttg atttctttgt tcaaataagg aatatgctgg
    18181 aagtaattgg catcaatgtc gccttcttcc aaagattggt tcggtaatac atagtcatcg
    18241 aatttgacga tttcaagatc gattccttca tctttcaata atggtttcac atgttccaaa
    18301 atctctgcgt gcggtgtcgg tgaagcgccg actttcaatg tcgtgtcgtc tgctttattt
    18361 gctgaatctt tgctgtcgct gttgttaccg catgctgcta atcctacagt cagcaaaagc
    18421 gctgctgcaa atccaaaaat tttctttttc atatcctaca tccccctata tcctattatc
    18481 ttttgtctgt tttcttagtt aagaaatcac cgattccttg aacgataaat acgattagta
    18541 aaataattaa agtcgcaacg aatgtcactg ttagattacc acgctggtag ccttcctgcc
    18601 aagcaagacc tccaagtcca cctgcgccga tcgcgccggc catcgcagta aatccgatca
    18661 tcgagatcgt tgtaactgtt aatccagaaa tcaatgcggg aatactttca ggtatcaaga
    18721 ccttccagat gatttcccag taacttgctc ccattgcatc tgctgcttcc agtacaccag
    18781 ggctgacttc acgaaaagca atctctacta gacgggcata aaatggtgct gcggataaaa
    18841 caagagctgg aatggctgct tgcgcaccta gcatagtgcc tacgattgct ttagtaaatg
    18901 gaatgatcaa aaccatcagg atcataaatg gcgttgaccg gaaaatatta ctgatgatcg
    18961 atacgattcc ataaatgatt cgagcatacg gtttgttttt gcgtccaata gagtaaagga
    19021 tcaatcccaa aactaatccg atgatcgtca ctaagaccat tgagattaat gtcatatata
    19081 gtgtatcaag gatagcctga ttcatcgttt ccgggttgat ttgtttaaaa tctagatatg
    19141 tttctgaaaa gcttttatcc acgatggatc acctcaattc ctactccttg ttctttgatg
    19201 aacacttctg cttgatctaa ttctttggtt tcaccagtca tcaagacagt caatgaacca
    19261 aaggaacctt ctttcacttg tttgatcttt ccatacacaa cgttgacatc gatgttatag
    19321 cgtcgaatcg cttgggaaat gactggctcg ttggcatttc tttcgctaaa ggtcaaagtt
    19381 gccaaacggc cgcttggatt ttctttgatg agttcagcta atagttctgt cgaatcagct
    19441 tctggttcga tgtcttgttg tacaaagcgt ttggttactt cttttttcgg ttgtctgaag
    19501 acagtcaata cgtctccttc ttctacgact ttccccaact ccatcacagc gactttgttg
    19561 cagattttgc ggatcacatt catttcatgt gtgatcaaga cgatggtcaa attcaatttc
    19621 ttattgatcg ctaacaataa gtctaatact tcttctgttg tttgcgggtc caatgcgcta
    19681 gtagcctcat cacaaagcag gatctcagga tcatttgcca atgctcgtgc gataccgacg
    19741 cgttgtttct gtccgccgga aagttgtgaa ggatatgctt gtccgcgtcc ttctaacccg
    19801 actaaacgca acagttcttc tgcccgttct ttacgtttgc tctttggtac gccagctaat
    19861 tccagcggca gctggatatt ttcaagtaca gttcttgacc ataacaggtt gaaatgctgg
    19921 aagatcatac cgattttctt tcggaatgta cgtaattctt tgttttttaa ttttgtaata
    19981 tcttgatcgt ttacgatcac ttcgccgctc gtgggaagct caagtccatt caggagacgg
    20041 actaatgtac tttttcctgc gccagaatag ccgacgattc cataaatatc ccctttttca
    20101 acgtttagtg aaacgtcatt gacggcttgg atgtttccgt ttttcccatt gaatgtcttt
    20161 ttgacattcg ttagttggat taatgacatg ccattcacat ctttctctta taatttttca
    20221 aacaaaaaag ccttcgccct cttgccttaa gcaaaaggac gaaagcttga acttccgtgt
    20281 taccaccttg atttaccgtt acttcgcaat aacagcctct tccagtactt ggacttagct
    20341 tctttccgta tactgtcgcg ctgtaacggg cactcccgta gtaagtttgc ttacgctcgc
    20401 ttactctgct ctaagaccat cttccatctc attttcgtta cccattttca gcaaacaggg
    20461 ctctcttcaa acgtccgtga catgtactct tcttttcaaa gctttctcgt ttcatatagg
    20521 attgcttatg attatagcaa ctggaagaat cagtgtcaac ttttttcaag tgattttctg
    20581 attttataat tcgtcaaatt cttttggatc aacatctttg aaacttaaga tccacgcatt
    20641 catttcatct gaatcattca agatattgat atcttcaccg attttatcat taacagaaga
    20701 aactgtaccc gttagcgggc tggcaaattc attgaccgct ttttccgctt caacttcgat
    20761 cagaggttca tcttttttta gcgattgtcc tgcttttggc agattggcaa acgtgatgtc
    20821 tccaagttct tcttgcgctt catttgtcaa accaacacag tattcttttc cattaaataa
    20881 gatccaaagg ttgtcctttt tcttcaaatg cttgcctgcc attttatatc agttctcctt
    20941 cataaatttt ttcattgaat ccaattgcaa caagctggtc ctctcgtaag atcagtggtc
    21001 gcttgatcag cataccatct gtcgataaga cttggctcgc ttttgaagcc gtaaactcgc
    21061 ctacttgatc tttcagtcca agttcccgat atttcatccc gcttgtgttg aacaggcgac
    21121 ggattggtac ttgactcgtt tctagccaag tctcaatcgt tgaggccttc ggtacttctt
    21181 tgatcatatc aacggtttga taactaacgc catgctggtc taaccacgct ttggcttttt
    21241 tgcatgttga acatttcggg taccagtaaa aggtgtacaa ttttcttacc tccttgaaga
    21301 tcttgcaggt gcttcatttt ggtatctcat cgataatatc aacccgatac cgatcatgtt
    21361 ccctaaaatc gaggatcctc cctgactaat gaaaggcaat gggatccctg ttaaaggaag
    21421 taatccgata tttgctccaa tattctcaaa gacatggaac agcagcatca tgatcaaacc
    21481 gcttgcgata taggcgtaaa attcattatt cgtatcgaaa cacacccgaa tcatacgata
    21541 gattaaaata aaatacaaga aaatgacgaa tgcaccaccg ataaagccga agttttcacc
    21601 gataacggta aaaatcatat cggactcacg aacaggcaca tagatattgc ttacgttgaa
    21661 tcctttacca aacaagccac cggtaccaat tgccaaaagt ccttgggccg gctgataact
    21721 cattcctgac gtatcatgga aagggtccag ccatgaatca atacgtgcaa actgataaga
    21781 tttgaatcca actttataaa gcaagtctct tccgccttca gtcgtaacca agaagatcgt
    21841 tcctgctcca acgactactg ccaagattac tacaggtgcg atgatgcgcc aagagattcc
    21901 agacatcagg aaaatcccgc caaagatcgc aagaaagaca agcatcgttc caaagtcatc
    21961 ttgggccatg atcaatgcta aaaccggtat tgtcacgatc aagagcttcc caatcagcca
    22021 aaagtccgat ttcatcgtcc gttcttttac ttgcgtatta tgtttagtta cgatcagtgc
    22081 catcatcaag atgtacgcaa tcttcatcaa ctctgctggc tggaaagtaa acgcaccgaa
    22141 tcgaaaccag tttttagacc ctgttgaagc agctaaattc tgatcataga atttgagcaa
    22201 gagtcccatt accactaacc ccaaaccata aaggtaagga gtcagtttcc agatccattt
    22261 ggaattcaaa tgcatgatga caacgattgc tgccgctcca actaaatacc agacaacttg
    22321 catccctacg cctttcaaga ctgctggatt gttcggatca tggctaagtg ctacatataa
    22381 tgagagcaga ccaatcaaac ataacagaaa gactggtaaa atcacgccat aatcaatacg
    22441 attatcgttc gaagctttta attttttttc catgtttcat cccttttctt aaaaaccata
    22501 ctgctgatta ttatagcggt ccagttagat aatggaaagt ctttccatag acatttggga
    22561 aaaattaact ttccgtttgt gcagttgctt gagcaaatgc agtacaaaag cctactgctt
    22621 atctttagtg tatcatagaa ctttttttga tacatgcaat tatctaccag ctgagattct
    22681 cctcgctgtg agaagtttct gtgctttcat tgtatcgaag gatctcttcg gcaatctcta
    22741 gcagctgatc agaaaccaga ttggttcgtt ggatgaaata aaaatatcga tggaaattca
    22801 acggagtcat tggcacattt tctggaacag agcgcttaga caaaatcgag cgaccgattc
    22861 cttccttcag caacgcaaca attacatcgt tacttttcac gatcatcttc ttatcttgga
    22921 tattcatctc ttcaaaataa cgcttcgtgt aatgaaaaac accagagttt gcttctctta
    22981 caagccacaa tttgcttttt gggtccccag cgatgactag ctggtcttcc atcaaagagt
    23041 atctttgtac gccggaagtc tctaatggct tttcgataaa accaaaatcg gattcatgtt
    23101 tcgctacttg ttctaatgat tcatgagaat tcgtgatttc gatctcaaaa tgcactttag
    23161 gaaacctttt gatcagatgt ttcatcaact gaggcaaaag atggacagca aaggtgtggg
    23221 aagcaacgat ccgacatact tcttcttcat tttgttcatt gagcaatttt tgctgagttt
    23281 cttcccattc ttctaacaaa accagtgtcc gttcatataa taagtcggct tgcttagttg
    23341 gaagcatctc ttttcttccg ttacgttgaa aaagatcgat attcaattcc cgctccaact
    23401 gtttgatttg attcgagact gctggttgag ataaaaacag tacttctgct gctctggaaa
    23461 aatttcttgt ttcatatact gctcgaaaag tcgttaataa cttaaacatg gcaccacttc
    23521 cataactttt tatgataatt actataaaaa ctatttgatt taaatataca aaaaaccatc
    23581 tataatagaa atgtacaaca aaacagttgc tgatccaact agtaacttag atgaagacaa
    23641 tcagctgtct gcttgctcgt aatcatacat tcctattcat tttacaatgt attcgttcat
    23701 cttggtacta aaatctatta aataaaaagg agaatattat atatgaagaa ctttttgaaa
    23761 attattccga tcccgatctg cgggttgatc cttgggttag cttcccttgg aaatctgttt
    23821 aaagactatc accatgttgc tttaggcaat ctaactggcg gtatctctat gattcttatg
    23881 atattcattt ttgttaaatt gtttatctta ttcgaacaca cgaaacaaac gttgcatgat
    23941 ccaatcatcg cctccgtttc accaactttt acgatgtcac tcatggttat ttgtacttat
    24001 tttgtttcat atgaaagtat tgcaccaatt gtcaaattca tttggctgtg cgctgttatc
    24061 ttccaagtga tccttgtctt ttatttcaat tatcaccatg ttatcaaagc tgatctttca
    24121 attgaagcaa tttatccaag ctggtttatc atttacgttg gatttggggt catcactgta
    24181 actgccggga acttcttccc acttattgga aaaattttct tttggatttc attgatctgc
    24241 tatgcgttct tattgccgat catcatcaaa cgtgtctttt tcgtaagaaa tatggctcat
    24301 ccgacacgtc cgctgattac gatcgttgca gcacctggtt ctctttgcct aacaggttat
    24361 cttaaaaact ttgctgaacc taatttttat cttgtcgtag cattgttcgc tttatctcaa
    24421 gtattgtatt tcgttgtgct gtctatgctt ccacgtttgt tcaagcttcg tttttatcca
    24481 agctatgcag cctttacatt cccgcttgtt atctctgcaa cagctatatt tactactgtt
    24541 cattacttca acagtttagg tatctatagt agcgtattgg atttcttaaa agttgcggaa
    24601 tgtctgtttg caagtgtagt tgtcttctac gttcttgctc attacgtacg tttcttaatt
    24661 aaagaacata gcaaacatgg aaaatttgtt tctaaaaaaa tcgcttaata atcgattcaa
    24721 taggttgtga aaaagctgtt ctgcatcaag taataagaac ggccaaacaa aaacagctgt
    24781 tcatgttttt gtactggttg ggcttattac cgcagatgca agcttttgaa caccgtttac
    24841 caagaggtcg taaaagaagt ggtcagcttc aagaaataag aaggaattta cgaaaattgc
    24901 ttctcaaatt tttgtgaaat ttcggcttat ttccgtagaa gctacttctg gaacaccgtt
    24961 tattcgaaac aagaggtcgt acaagacttt tgtcacgacc tcttgttctt ttgtcaaaat
    25021 actggtttag tgctactatg ttcgagtatg cttttagtat ttattgacga aaggaaccga
    25081 tcaaatgaaa tcattgtcac atccaataaa atctgtaaag gattcagcgg tccgcgaaat
    25141 cttacccggt ttactgcttt cttttgccat cgctgccttc agcaggcttc ttgctattta
    25201 tctgccacag ttaggtggag cgactattgc tattttattg ggtattttat taggaaatac
    25261 tttttttaaa cagcctgttc tagcaatcgg cacaaaattt gctgaaagca aactattaga
    25321 attctctgtt tttttactag gtgcaactgt cacagctcaa acgattgctc aaattggtgt
    25381 aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact atcatcggtg cttacttgat
    25441 tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg atggctggag gaaacgctgt
    25501 ttgtggttct tctgctattg cttcaatcgc cccttccatc catgcgaaag aggaagaaaa
    25561 aggacagatc atcacactag tcaatctact gggtactgtg atgatgttga ctctcccttt
    25621 tcttggatta cagttgtttg gtggaaatct cattgaaaaa agtgcacttt tgggtggtac
    25681 actccaatct gttggtcaag tagtcgctgg ggcaagctta cttgacaatt ctgttgtcga
    25741 attcgccatg ctatttaaga ttctacgtat tatgatgctc gttgttgttg tctatctgtt
    25801 tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa acgccaactg atacgcagaa
    25861 aaaacgaaaa ttaccgcttc cttggtatgt attagggttt gtgatctttt gtttggtcaa
    25921 cagcttgttt tctttacctg tagttattga ccaatcggca cattttatca gcagctggtt
    25981 tgagatcact gctttagcgg caattggtct gcgtttagac tttgcaaaat tcatgaaaga
    26041 aggtacacgc ttcttatctt atggattagc tgtcgggctt ctccaaacag tgatggcttt
    26101 actatttatt tggctgatca aagtttagaa tgaacatgaa aaaacagttg tgattctcgc
    26161 atggaacaat gtccgaatca caactgtttt taattttgca gatatccttc taacaacaac
    26221 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
    26281 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
    26341 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
    26401 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
    26461 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
    26521 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
    26581 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
    26641 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
    26701 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
    26761 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
    26821 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
    26881 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
    26941 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
    27001 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
    27061 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
    27121 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
    27181 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
    27241 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
    27301 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
    27361 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
    27421 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
    27481 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
    27541 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
    27601 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
    27661 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
    27721 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
    27781 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
    27841 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
    27901 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
    27961 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
    28021 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
    28081 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
    28141 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
    28201 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
    28261 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
    28321 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
    28381 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
    28441 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
    28501 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
    28561 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
    28621 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
    28681 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
    28741 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
    28801 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
    28861 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
    28921 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
    28981 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
    29041 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
    29101 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
    29161 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
    29221 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
    29281 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
    29341 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
    29401 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
    29461 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
    29521 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
    29581 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
    29641 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
    29701 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
    29761 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
    29821 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
    29881 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
    29941 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
    30001 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
    30061 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
    30121 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
    30181 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
    30241 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
    30301 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
    30361 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
    30421 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
    30481 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
    30541 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
    30601 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
    30661 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
    30721 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
    30781 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
    30841 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
    30901 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
    30961 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
    31021 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
    31081 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
    31141 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
    31201 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
    31261 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
    31321 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
    31381 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
    31441 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
    31501 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
    31561 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
    31621 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
    31681 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
    31741 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
    31801 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
    31861 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
    31921 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
    31981 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
    32041 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
    32101 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
    32161 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
    32221 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
    32281 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
    32341 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
    32401 tccagtgcat ttggttatcg cggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
    32461 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
    32521 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
    32581 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
    32641 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
    32701 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
    32761 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
    32821 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
    32881 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
    32941 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
    33001 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
    33061 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
    33121 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
    33181 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
    33241 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
    33301 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
    33361 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
    33421 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
    33481 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
    33541 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
    33601 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
    33661 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
    33721 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
    33781 tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa tcattacttt
    33841 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
    33901 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
    33961 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
    34021 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
    34081 taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata agaatagatt
    34141 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
    34201 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
    34261 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
    34321 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
    34381 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
    34441 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
    34501 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
    34561 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
    34621 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
    34681 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
    34741 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
    34801 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
    34861 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
    34921 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
    34981 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
    35041 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
    35101 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
    35161 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
    35221 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
    35281 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
    35341 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
    35401 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
    35461 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
    35521 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
    35581 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
    35641 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
    35701 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
    35761 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
    35821 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
    35881 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
    35941 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
    36001 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
    36061 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
    36121 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
    36181 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    36241 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    36301 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    36361 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    36421 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    36481 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    36541 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    36601 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    36661 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    36721 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    36781 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    36841 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    36901 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    36961 tactttatca gtgatatgca ctttttccat gaacgcttat taggaaaaaa cgactttgct
    37021 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    37081 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    37141 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    37201 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    37261 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    37321 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    37381 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    37441 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    37501 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    37561 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    37621 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    37681 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    37741 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    37801 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    37861 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    37921 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    37981 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    38041 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    38101 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    38161 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    38221 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    38281 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    38341 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    38401 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    38461 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    38521 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    38581 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    38641 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    38701 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    38761 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    38821 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    38881 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    38941 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    39001 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    39061 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    39121 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    39181 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    39241 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    39301 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    39361 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    39421 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    39481 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    39541 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    39601 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    39661 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    39721 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    39781 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    39841 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    39901 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    39961 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    40021 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    40081 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    40141 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    40201 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    40261 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    40321 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    40381 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    40441 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    40501 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    40561 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgagaacgc
    40621 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    40681 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    40741 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    40801 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    40861 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    40921 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    40981 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    41041 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    41101 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    41161 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    41221 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    41281 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    41341 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    41401 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    41461 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    41521 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    41581 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    41641 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    41701 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    41761 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    41821 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    41881 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    41941 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    42001 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    42061 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    42121 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    42181 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    42241 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    42301 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    42361 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    42421 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    42481 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    42541 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    42601 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    42661 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    42721 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    42781 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    42841 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    42901 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    42961 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    43021 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    43081 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    43141 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    43201 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    43261 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    43321 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    43381 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    43441 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    43501 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    43561 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    43621 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    43681 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    43741 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    43801 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    43861 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    43921 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    43981 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    44041 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    44101 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    44161 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    44221 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    44281 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    44341 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    44401 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    44461 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    44521 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    44581 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    44641 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    44701 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    44761 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    44821 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    44881 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    44941 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    45001 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    45061 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    45121 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    45181 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    45241 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    45301 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    45361 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    45421 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    45481 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    45541 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    45601 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    45661 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    45721 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    45781 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    45841 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    45901 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    45961 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    46021 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    46081 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    46141 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    46201 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    46261 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    46321 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    46381 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    46441 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    46501 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    46561 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    46621 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    46681 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    46741 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    46801 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    46861 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    46921 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    46981 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    47041 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    47101 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    47161 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    47221 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    47281 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    47341 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    47401 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    47461 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    47521 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    47581 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    47641 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    47701 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    47761 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    47821 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    47881 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    47941 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    48001 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    48061 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    48121 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    48181 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    48241 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    48301 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    48361 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg
    48421 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    48481 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    48541 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    48601 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    48661 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    48721 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    48781 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    48841 gtgtattcct cccgtaacaa attagaaagc gtttacttaa agtattacct aatttatttt
    48901 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa a
//
LOCUS       DAIGSZ010000017        44823 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.017, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000017 DAIGSZ010000000
VERSION     DAIGSZ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.017"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..1008)
                     /locus_tag="NOB31_000974"
     CDS             complement(<1..1008)
                     /locus_tag="NOB31_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0973200.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="NOB31_000975"
     CDS             complement(1188..1532)
                     /locus_tag="NOB31_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCI0973201.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="NOB31_000976"
     CDS             complement(1525..1959)
                     /locus_tag="NOB31_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HCI0973202.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="NOB31_000977"
     CDS             2097..2834
                     /locus_tag="NOB31_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0973203.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="NOB31_000978"
     CDS             2827..4038
                     /locus_tag="NOB31_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973204.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4242..5024
                     /locus_tag="NOB31_000979"
     CDS             4242..5024
                     /locus_tag="NOB31_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HCI0973205.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="NOB31_000980"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="NOB31_000980"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HCI0973206.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="NOB31_000981"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="NOB31_000981"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HCI0973207.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="tadA"
                     /locus_tag="NOB31_000982"
     CDS             7740..8669
                     /gene="tadA"
                     /locus_tag="NOB31_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HCI0973208.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /locus_tag="NOB31_000983"
     CDS             8626..9675
                     /locus_tag="NOB31_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HCI0973209.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /locus_tag="NOB31_000984"
     CDS             9672..9950
                     /locus_tag="NOB31_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCI0973210.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /locus_tag="NOB31_000985"
     CDS             9925..10395
                     /locus_tag="NOB31_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HCI0973211.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10412..10714
                     /locus_tag="NOB31_000986"
     CDS             10412..10714
                     /locus_tag="NOB31_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973212.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10731..11102
                     /locus_tag="NOB31_000987"
     CDS             10731..11102
                     /locus_tag="NOB31_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HCI0973213.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /locus_tag="NOB31_000988"
     CDS             11074..11433
                     /locus_tag="NOB31_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973214.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="NOB31_000989"
     CDS             11605..12612
                     /locus_tag="NOB31_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0973215.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="NOB31_000990"
     CDS             12637..13821
                     /locus_tag="NOB31_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HCI0973216.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /locus_tag="NOB31_000991"
     CDS             complement(14258..15841)
                     /locus_tag="NOB31_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI0973217.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16419..16562)
                     /locus_tag="NOB31_000992"
     CDS             complement(16419..16562)
                     /locus_tag="NOB31_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HCI0973218.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="NOB31_000993"
     CDS             complement(16785..17264)
                     /locus_tag="NOB31_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI0973219.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="NOB31_000994"
     CDS             complement(17337..17621)
                     /locus_tag="NOB31_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973220.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="NOB31_000995"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="NOB31_000995"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="NOB31_000996"
     CDS             complement(17965..19251)
                     /locus_tag="NOB31_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HCI0973221.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="NOB31_000997"
     CDS             19389..20060
                     /locus_tag="NOB31_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HCI0973222.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="NOB31_000998"
     CDS             20026..20514
                     /locus_tag="NOB31_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HCI0973223.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="NOB31_000999"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="NOB31_000999"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HCI0973224.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="NOB31_001000"
     CDS             21475..22239
                     /locus_tag="NOB31_001000"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HCI0973225.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="NOB31_001001"
     CDS             22472..24685
                     /locus_tag="NOB31_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HCI0973226.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /locus_tag="NOB31_001002"
     CDS             24696..25142
                     /locus_tag="NOB31_001002"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HCI0973227.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="NOB31_001003"
     CDS             25313..26572
                     /locus_tag="NOB31_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HCI0973228.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="NOB31_001004"
     CDS             complement(26661..27608)
                     /locus_tag="NOB31_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI0973229.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /locus_tag="NOB31_001005"
     CDS             28002..29294
                     /locus_tag="NOB31_001005"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HCI0973230.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="NOB31_001006"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="NOB31_001006"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HCI0973231.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="NOB31_001007"
     CDS             31187..32062
                     /locus_tag="NOB31_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0973232.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="NOB31_001008"
     CDS             32328..34211
                     /locus_tag="NOB31_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HCI0973233.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="NOB31_001009"
     CDS             complement(34286..34570)
                     /locus_tag="NOB31_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCI0973234.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="NOB31_001010"
     CDS             complement(34560..35294)
                     /locus_tag="NOB31_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HCI0973235.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="NOB31_001011"
     CDS             35423..36046
                     /locus_tag="NOB31_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HCI0973236.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="NOB31_001012"
     CDS             36238..37359
                     /locus_tag="NOB31_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HCI0973237.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="NOB31_001013"
     CDS             37366..40494
                     /locus_tag="NOB31_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HCI0973238.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="NOB31_001014"
     CDS             40513..43707
                     /locus_tag="NOB31_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HCI0973239.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="NOB31_001015"
     CDS             complement(43853..44560)
                     /locus_tag="NOB31_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI0973240.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14381 a         7961 c         9407 g        13074 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaaggcaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgaa aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaacta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgatcgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgctc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggc
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagct agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ctatttcctt gacagaataa ggtttttata
    44701 tttcagtttt tttcactaaa aatcgtgaaa cacgtcaata agtttgatga acaaattaat
    44761 cattatggta gaagtcgatt gatttatttt aatgcaatct ctgtggaatt ttcgaaagat
    44821 tta
//
LOCUS       DAIGSZ010000018        44766 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.018, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000018 DAIGSZ010000000
VERSION     DAIGSZ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.018"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            14..646
                     /locus_tag="NOB31_001016"
     CDS             14..646
                     /locus_tag="NOB31_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973241.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(780..905)
                     /locus_tag="NOB31_001017"
     CDS             complement(780..905)
                     /locus_tag="NOB31_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0973242.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(1039..1932)
                     /locus_tag="NOB31_001018"
     CDS             complement(1039..1932)
                     /locus_tag="NOB31_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HCI0973243.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(2114..3040)
                     /locus_tag="NOB31_001019"
     CDS             complement(2114..3040)
                     /locus_tag="NOB31_001019"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HCI0973244.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(3125..3886)
                     /gene="pflA"
                     /locus_tag="NOB31_001020"
     CDS             complement(3125..3886)
                     /gene="pflA"
                     /locus_tag="NOB31_001020"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HCI0973245.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(4130..6361)
                     /gene="pflB"
                     /locus_tag="NOB31_001021"
     CDS             complement(4130..6361)
                     /gene="pflB"
                     /locus_tag="NOB31_001021"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HCI0973246.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6638..9088)
                     /gene="parC"
                     /locus_tag="NOB31_001022"
     CDS             complement(6638..9088)
                     /gene="parC"
                     /locus_tag="NOB31_001022"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HCI0973247.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(9100..11145)
                     /gene="parE"
                     /locus_tag="NOB31_001023"
     CDS             complement(9100..11145)
                     /gene="parE"
                     /locus_tag="NOB31_001023"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HCI0973248.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(11311..11745)
                     /locus_tag="NOB31_001024"
     CDS             complement(11311..11745)
                     /locus_tag="NOB31_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HCI0973249.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11872..12510
                     /gene="plsY"
                     /locus_tag="NOB31_001025"
     CDS             11872..12510
                     /gene="plsY"
                     /locus_tag="NOB31_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HCI0973250.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12642..13517)
                     /locus_tag="NOB31_001026"
     CDS             complement(12642..13517)
                     /locus_tag="NOB31_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCI0973251.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13599..14390)
                     /gene="codY"
                     /locus_tag="NOB31_001027"
     CDS             complement(13599..14390)
                     /gene="codY"
                     /locus_tag="NOB31_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HCI0973252.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(14408..15808)
                     /gene="hslU"
                     /locus_tag="NOB31_001028"
     CDS             complement(14408..15808)
                     /gene="hslU"
                     /locus_tag="NOB31_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HCI0973253.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15822..16370)
                     /gene="hslV"
                     /locus_tag="NOB31_001029"
     CDS             complement(15822..16370)
                     /gene="hslV"
                     /locus_tag="NOB31_001029"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HCI0973254.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(16407..17312)
                     /gene="xerC"
                     /locus_tag="NOB31_001030"
     CDS             complement(16407..17312)
                     /gene="xerC"
                     /locus_tag="NOB31_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HCI0973255.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(17510..18886)
                     /gene="trmFO"
                     /locus_tag="NOB31_001031"
     CDS             complement(17510..18886)
                     /gene="trmFO"
                     /locus_tag="NOB31_001031"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HCI0973256.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18855..20933)
                     /gene="topA"
                     /locus_tag="NOB31_001032"
     CDS             complement(18855..20933)
                     /gene="topA"
                     /locus_tag="NOB31_001032"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HCI0973257.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(21055..21912)
                     /gene="dprA"
                     /locus_tag="NOB31_001033"
     CDS             complement(21055..21912)
                     /gene="dprA"
                     /locus_tag="NOB31_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HCI0973258.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21968..22735)
                     /locus_tag="NOB31_001034"
     CDS             complement(21968..22735)
                     /locus_tag="NOB31_001034"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HCI0973259.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22728..23588)
                     /gene="ylqF"
                     /locus_tag="NOB31_001035"
     CDS             complement(22728..23588)
                     /gene="ylqF"
                     /locus_tag="NOB31_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HCI0973260.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            23848..24246
                     /locus_tag="NOB31_001036"
     CDS             23848..24246
                     /locus_tag="NOB31_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0973261.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            24525..25025
                     /locus_tag="NOB31_001037"
     CDS             24525..25025
                     /locus_tag="NOB31_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCI0973262.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(25108..25659)
                     /gene="lepB"
                     /locus_tag="NOB31_001038"
     CDS             complement(25108..25659)
                     /gene="lepB"
                     /locus_tag="NOB31_001038"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCI0973263.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(25811..26038)
                     /locus_tag="NOB31_001039"
     CDS             complement(25811..26038)
                     /locus_tag="NOB31_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HCI0973264.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(26035..26553)
                     /gene="msrA"
                     /locus_tag="NOB31_001040"
     CDS             complement(26035..26553)
                     /gene="msrA"
                     /locus_tag="NOB31_001040"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI0973265.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(26573..27286)
                     /locus_tag="NOB31_001041"
     CDS             complement(26573..27286)
                     /locus_tag="NOB31_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HCI0973266.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(27289..28185)
                     /locus_tag="NOB31_001042"
     CDS             complement(27289..28185)
                     /locus_tag="NOB31_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI0973267.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(28343..29185)
                     /locus_tag="NOB31_001043"
     CDS             complement(28343..29185)
                     /locus_tag="NOB31_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI0973268.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            29317..29970
                     /locus_tag="NOB31_001044"
     CDS             29317..29970
                     /locus_tag="NOB31_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HCI0973269.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(30033..30560)
                     /locus_tag="NOB31_001045"
     CDS             complement(30033..30560)
                     /locus_tag="NOB31_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI0973270.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(30580..31527)
                     /locus_tag="NOB31_001046"
     CDS             complement(30580..31527)
                     /locus_tag="NOB31_001046"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HCI0973271.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(31539..33425)
                     /locus_tag="NOB31_001047"
     CDS             complement(31539..33425)
                     /locus_tag="NOB31_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI0973272.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQKEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(33585..35663)
                     /locus_tag="NOB31_001048"
     CDS             complement(33585..35663)
                     /locus_tag="NOB31_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HCI0973273.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(35676..35951)
                     /locus_tag="NOB31_001049"
     CDS             complement(35676..35951)
                     /locus_tag="NOB31_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973274.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(36313..36768)
                     /locus_tag="NOB31_001050"
     CDS             complement(36313..36768)
                     /locus_tag="NOB31_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973275.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(36922..38130)
                     /locus_tag="NOB31_001051"
     CDS             complement(36922..38130)
                     /locus_tag="NOB31_001051"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HCI0973276.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(38242..38574)
                     /locus_tag="NOB31_001052"
     CDS             complement(38242..38574)
                     /locus_tag="NOB31_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCI0973277.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            38722..39597
                     /locus_tag="NOB31_001053"
     CDS             38722..39597
                     /locus_tag="NOB31_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0973278.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(39679..40260)
                     /locus_tag="NOB31_001054"
     CDS             complement(39679..40260)
                     /locus_tag="NOB31_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HCI0973279.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(40266..41525)
                     /locus_tag="NOB31_001055"
     CDS             complement(40266..41525)
                     /locus_tag="NOB31_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCI0973280.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(41527..42573)
                     /locus_tag="NOB31_001056"
     CDS             complement(41527..42573)
                     /locus_tag="NOB31_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973281.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(42808..43083)
                     /locus_tag="NOB31_001057"
     CDS             complement(42808..43083)
                     /locus_tag="NOB31_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HCI0973282.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(43326..44636)
                     /gene="der"
                     /locus_tag="NOB31_001058"
     CDS             complement(43326..44636)
                     /gene="der"
                     /locus_tag="NOB31_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HCI0973283.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
BASE COUNT        12089 a         9408 c         7656 g        15613 t
ORIGIN      
        1 atttggagat attatggaaa ttcaacgtag aaccactaat tttttacatt taggctcttt
       61 ttttgcaact ttgacgatct tattttttct atgttattca taccttaaga cctcacatgc
      121 gccttctagt gcattaggct ggttgctttt ggatcattct gatatcacag aagccgaaga
      181 aaatccgttt tttttgattt tgtcttctct ttgcggctta ctgttttctg tttatttcgg
      241 tgcctatttt tttcatcgac atcctggtac gttaaacgaa gcttcaagcg tattgattgc
      301 atttaaaacg ttttcttttt tagcaattct tttttattcg tttaatcaca atacgctttt
      361 cttctttatc atgaatggtt tagtcgtgat tttatccatt tttacttatt ttattttttc
      421 actcattttt agccaattga aatgtccgct cttctttcga ttagttcctg tcacctgttt
      481 tatttacagc ttgttttcct tttttgtcct tgctttaatg ccactgacca acccttcgac
      541 gatccaagtc gcaggaaatc tgttggatat gctcttcatc gtcagtctag gtgtatttat
      601 gtggcaaaga aaaaacaaac aaaataaaaa gcattttgaa gcctgactat tacgacttca
      661 taaatgcttt tttagtttta aacacttcaa tctaaaagaa taacccaaga ttggataaat
      721 tattaatgac tcgccattcg tttcttagtg attctggatt atcaaatgga cttcctaatc
      781 taatcagcta gttcttccca taaaatgcca tacttgactg aatcataata ttgattattt
      841 aaaaatctaa cttttcttat cactacttcc tttgtcattc cacatttctc accatttttt
      901 tgcattcctt tgtttccaga ccatgtagtg aatctaatag gtggtagata ggcaaaatac
      961 tcaaataatt cttttaacca taaaggaaga gaaaggctcc tcctgcaaga gtcagtataa
     1021 tttttgctta ctgctctctt aggttttact cactaaaact gttccatatt ctttgatata
     1081 agaaaatgca tgcggtataa atttcttgct cagctcagaa aagatttgtc gtttaagaaa
     1141 ggccatttcc tccattgtca atgaaggatc caatgttggt aattcaatct caaaattgtt
     1201 tttttcgaca ataggtaatt ctaatgtgaa tgattcttct tcctttatag tattcgtcac
     1261 aagtagagac tgatggaaaa tactaggccg gcgattttta tatttattct tacgtatcct
     1321 gtcaacgata acttctattt gatcaaaaaa gtacgattca tttacgtctc caataagttc
     1381 ggctaattct ttgaatgcct tcgttacagg aagctgattc ttctgtacaa aaaagtaatt
     1441 agccaaagta agcgggaagt gttctataga ggaaagtgtg ataaaacggt acttctcatt
     1501 tcctgcagtt gtcctcagca attctgtctc tcggctgttt cttactccat aaaaatacgc
     1561 ttctttccgt tcatcttcga aacaatacgc ccaaataact tctcccatcg ctaatttttg
     1621 ttcatcaaca gagagtctct tcaattgttc agctatggtt tcagcagccg aagtggcttg
     1681 ttgcaagtaa tctttaggat caaatattgg aaagttcaaa tgatatcttc gttcttccct
     1741 cttgattaat cctgcatcga tcaataaatc aagaaaatgg gaaaatttat tttgcgaaaa
     1801 ttcttttttc aattctctta gaatcgtttc ttgttctcga tgttcatata gataatcggt
     1861 caatgaagaa aaaagcggat catcggtcag tttttgataa aagttttcct tattttttga
     1921 ataatagttc atatatgttc tcttttctat ccgttttatt ttacttaaaa ggcttttacg
     1981 taaaaaggag gaagaacaag agtcataatt gactgttatt ctcctccatt tcttcggcct
     2041 ttagtatgtt ctatgtttct ttttatatca atcgcttatc cattcatttt gaatgcttca
     2101 tactaccatt tgattagcta aatacagccg tcaattgagg tacgacttgt tttttacgtg
     2161 aaacgacacc tttaagcaaa gcacggttgt tggtcaaagt tgtttggaaa gcttcttcta
     2221 ctttttcttt tcctttacca gcaacaagta attctgaatc actgtctaag atgtttgtga
     2281 caactaatac gaacagatcg tagccatttg ctttcatttc atcttccatt gctgcttcta
     2341 gctctgcttg tcgatccatc acttcattaa ggtccactgt attgacttga gcgatacgaa
     2401 cgttggaact gcccattggg aaactttttg catccaaatc aagaagaacc gcagctgatt
     2461 tatcacttag atttgttcct gctttcaaca tttcaagtcc ataagtgttt agatcgactt
     2521 cagcgattgc tgcaagttct tttgcagctg cttcatcttc aggcgtacat gttggtgatt
     2581 tgaacaacaa tgtatctgaa atgatagctg agagcatgat tcctgcgatt tctttaggaa
     2641 ttgttacttg gttttcttta tatagtttta aaataatcgt acttgtacat ccaactggtt
     2701 ctgcacgata gtacaatgga ttagctgttt caaagtttgc aatacgatgg tggtctacta
     2761 cagctaaaat atttacttcg ctgatatctg aaatactttg ttggaattca ttatgatcca
     2821 caagcatgac atctgcattt tctgctttag ctgactctac tactcgtggt gcagatagct
     2881 gaaagtggtc taatgcgtat tgtgtttctt cattaggtgt acctagagca actgcttctg
     2941 tttctttacc taattcattt tgcaagtgtg aaaacgcaat ggctgccccg attgcatctg
     3001 tatctggatt ttggtgacca aaaactaaaa tttttgacat gtcattcgct cctttgtgat
     3061 ttctcctatt taataatagc aaaaaaacgg aaagaagcaa tacttatctt ctttccgatg
     3121 cgacctatcg cgttaaatat tttgtatact cttctgtatg aagcaatcgt ttagcatttt
     3181 cgacacgttc ttttgtaggt ggttcgatcc cttctaatgg atatttcaaa ccaagtgttt
     3241 cccacttgta ttttcccatc gtatgataag gaagaatctc tactctgtct acatttgaca
     3301 aggtttgaat aaagttgtct agtcggatca aatattcatc ataatcactt cgctcaggaa
     3361 ctagtacatg gcgaatccaa accggtttgt tgatttttga caaatattga gccatttcta
     3421 aaatattttc attgtcccaa tgcgttagtt ttttatgctc ttcattatcg atgtgtttga
     3481 tgtcaaataa cagtaaatct gtatacttca tcaattcttg aaaacgtgaa aagaaaggtt
     3541 cttcatacgt aaaaggtttt ccgcatgtat ccaatgtagt atgcatcttc cgctcttttg
     3601 cttttttaaa tagttcgatc aaaaaatcga tctgcaatag aggttctcca ccactaacag
     3661 taataccacc tttatctccc cagtaaggtc tgaagcgttc tgctttatct aaaagttcat
     3721 ctgctgtgta ttctttccct ccgccaatat tccaagtatc tggattgtga caaaattggc
     3781 aacgcatgcg gcatccttgc ataaacacga caaagcgcag tccaggtccg tctactgaac
     3841 cgaaagtttc gatagaatga acatagccga ttgttttttc ttccatttaa gttcacatct
     3901 tttctttgat ttcattttaa gtacaagtta gctgtcgaag cgaagctttc tgaacaaaat
     3961 ttttcgcaat tgccgcttcg ttatgtgtaa aatttacagg gacggaacat acaagtcctg
     4021 cccctgtaaa tcgtttcttt caaataagca tactgattat tcgattttga tgcgatggct
     4081 attcaacgtc ctttcgacgc taagtcgaaa aacttttttc acgaactttt tacattctgt
     4141 cgtgtgaagt tctcatcaag acatctaatt gttgttctct tgtcaagtca cggaatttaa
     4201 ctgcataacc agatacccgg atcgtcaagt tcggatattt cattggattt tccattgcat
     4261 cacgcaataa atcattactg aatacattga cattcaaatg ataagctcct tttgagaagt
     4321 atccatctaa gacattacgc aagttttcga ttcttgtatc ttgttctttt ccaagacctg
     4381 aaggattgat tgtttgggta tttgaaattc catccaatgc acagccgtaa ttcattttag
     4441 ctgttgagtt caggctagct aataacccac tttgttccgc attgtaactt ggatttgctc
     4501 ctggcgcaag tggttttcca gcttcacggc catcaggagt atttcctgta tttttaccgt
     4561 aaacaacatt tgaagtaatc gtcaataatg aagttgttgg ttttgagttg cggtaagttt
     4621 tatgacgttt gatttgtccc atgaagtatt ccaagatcca tgaaactaat tcatctgcac
     4681 ggtcatcatc atttccgtat ttagggaagt cgccatccac ttcaaaatca actgctattc
     4741 ctttttcatt acggattgct tttacttttg catatttgat cgctgacaag ctgtctgccg
     4801 catgagagat cccagcaata cctgtagcaa atgtgcgttg caagtcagaa tccatcaaag
     4861 ccagctgagc tgcttcataa gaatatttat catgcatata atgaatgatg ttcaacgtat
     4921 tgacatatag ttctgctaac caatccatca tattcatgaa gttatgtttc acttcttcaa
     4981 agtctagtat ttctgatgtg attggacgat attctggtcc aacttgggcg ccagtcactt
     5041 catcgactcc gccattgatg gcatataata gtgttttagc caagttagca cgagcgccaa
     5101 agaattgcat gtcttttccg acaactgttc ctgatacaca gcaagcaatc gcacaatcat
     5161 cagaacccca ttgttcacga agctgattat cattttcgaa ttgaatcgaa gaactttcga
     5221 tagcgattct gctagcatat gttctgaatc cttctggaag gtgttcagaa tacaaaacag
     5281 tcaagtttgg ttctggtgaa ggtcccatat ttgttaatgt atgaagcaga cggaaatcat
     5341 tctttgtaac taatgaacga ccatctaatc ccatacctgc aatggataaa gtagcccaga
     5401 tagggaatcc tgagaataat tggttatatt caggtgtacg cgcgaatttg accatacgta
     5461 atttcattac taagtggtcg atcaattctt gtgcttcttt ttctgtgatt actccattat
     5521 ccaaatcacg ttggatatag atatcaagga atgctgagat acgtccgatt gacatcgcag
     5581 caccattttg tgatttgatt gctgctaaat atccgaagta tagccattgg acagcttctt
     5641 ttgcatttgc agctggttta gaaatatcat agccatattt cgcagccatt tctttcattt
     5701 gcgctaatgc acgatattgt tcagtgattt cttcacgtaa acgaatcact tcttcactca
     5761 ttgtatgata accagtcata tcatgatctt ttttcttttg ttccatcaaa tagtcgattc
     5821 catacaatgc cacacgacga tagtcaccga tgatacgtcc gcgaccgtaa gcgtctggaa
     5881 gccctgtaat gattttgttt ttacgagcag cacgcatttc agcagtataa gcgtcaaata
     5941 caccttgatt atgtgttttg cgccagtcag tgaaaatatg tgtcaattca tcgtttggtg
     6001 tatagccatt gctttttagc gcattgttag ccatattgat tccgccgaac ggcatgaatg
     6061 cttgtttcaa aggtttgtct gtctgtagac cgacgatttt ttccaaatct ttatccaaat
     6121 agcctgcatc gtgtgaagta atagttgata cgatttctgt gtccatatca tagacaccgt
     6181 tacgctcgaa ttggatatca tttaactttt gcaattcatc ccataatttt tctgttgctt
     6241 ctgttgggcc ttccaaaaag ctgtcatcac cgcgatattc agtgtagtta ttttgaataa
     6301 agtctctagt gtctacgcct tctttccatt tggtaccttt aaatccattc cattgctcca
     6361 ttgtatggac ctcctaaatt tctgttttat gtaacagttt ttacgtgatt agtataacac
     6421 agcaccctat ctttgcaagg gttttcttgt tttttattta acaattttta tgttttattt
     6481 acatatattt aaatcaacgt tgacatacca acatttaagc attgtgaaca ctttcatctt
     6541 tttttgcaaa cgtataagga tttattaaaa atgaatgaaa aagagacgcc acctgtatta
     6601 atacagatgg cgtctcttca ttaaaatact acaacagtta cgactcgatg aaaatctcag
     6661 gagcatcgat aacttcgatg acttctccac cttttttctc atccatcgca aatgatccat
     6721 tcgatgttcg atcacctata gggaaatcag ttgggtcaat cgttaactgc tgcccttttt
     6781 gattcatcaa ggttatttct tttgatcttc cttccgacat atagataata cggtgcggat
     6841 tttttttcag ctcacgcatg accgtcactc cccgcttcgc acgtgaagtt tggctgattt
     6901 cttgagcaag catgcgttta acagctcctc gctgagtaac gattacgatc ggcgtatcac
     6961 cttctgctaa cacaagcagc ccgttgataa tcctatctcc atctttcaaa ttcatagact
     7021 tcactccagc tgcctttgct ccaacaacgg gaacatctgt taaaggatag cgcaaaccca
     7081 ttccttgatg cgttactaag aaaacatcta agcctggctg atcttctttc agatacacag
     7141 caatcagttc atcttcttcc gcctttagct tcatacagct gagcggacgg ctcttatagg
     7201 tgcgccatgg ttcgaactct gtcattcgtg tttgcttgat caatccattc ttgctgatga
     7261 atacaaatgt tttctctgct tgaatttttt gatatgggaa aacagctaaa atcgattcgt
     7321 ctacagacag attggagatt gtttgagaaa tgtgctcacc agcatctttc catttcaaat
     7381 cgggtagttc atggacaggg cggtagatca catttgcttt atttgtgatc agaagaacat
     7441 ggtccaatgt actcaattca cctgagtata gcaagtagtc gccttctcgc atcccgattt
     7501 cttctggttt ggaagcacta taagaacgaa ggcttgttcg cttcacatag ccttctcgcg
     7561 tcacactgac aattacgtct tcttgtgcca ctaagacttg cgtatcaatt ttgatttctt
     7621 cgatttcgtc ttcgattgtc gttagacgag cggaagaata attttttttc acttctcgca
     7681 attctttttt cataacagag aaaagctctt tgtcatttga aaggatttta ttcaactctg
     7741 tgatttgcgc aatcaagctt tcggattcct tttgaagctc tgtgatatcc gtgttcgtca
     7801 aacggtataa ttgcaatgtg acaattgctt ctgcttgttc ttctgtaaat tgaaagacgt
     7861 cgactaaatt ctttttggcg tcttttttgt ctttactttc acgaatcgtt gcgattactt
     7921 catccagaat cgataaagct ttcatcaatc cttctacgat atgctgtctt ttttgagctt
     7981 tggctaaatc gaattgacta cgttttgtta tgacttgctt tcgatgctcg atataacttc
     8041 ttaaaatgtc tttcagtcca acttgatgcg gagtcatatg gtcgatagcg accatattga
     8101 aattgtaatt gatctgtagc tcagtgtttt tgaacaaata attcaaaatt ccttgagcat
     8161 tggcgtcttt tttcaattcg acgacaattt gcagacctgt tctatcactt tcatctcgta
     8221 cttcagctat tccatcgatt ttcttattca aacggatctc atccattttt ttcaccaagg
     8281 tcgctttatt tacttcatat gggatttctg tgatcacgat ttgctgttta ttacccttca
     8341 ttgcctctat ctttgttttc gaacgaagaa taacttttcc tcgtcctgtt tcataagctt
     8401 ttttgatttc atcttttcct tgcaagatcc ctcctgttgg aaagtcaggt ccaggaatat
     8461 attccatcaa tttttcaagg ctcgcttgtg gatgatcgat catatagatt gtgccatcga
     8521 tcacttcagc taagttatga gtcgggattt ctgttgcata tccagcagat atacctgtcg
     8581 atccattgac gagaaggttt gggtatcgag ctggaaggac tgttggttct ttttctgtat
     8641 catcaaaatt ccacacgaga tcgactgttt ctttctcgat atctgctagc atctctccac
     8701 ttaacttgga taatctggct tcagtataac gcatcgcagc aggtggatca ccgtccatac
     8761 tcccgttatt cccgtgcatt tcgatcagta cttcccgcaa cttccagtct tggctcatgc
     8821 ggaccatcgc ttcataaata ctgatgtcac catgaggatg ataattcccc atgatatttc
     8881 cgacagattt tgctgattta cggaatcctt tgtcatacgt attgccatct ttgttcatgg
     8941 caaataatat ccggcgttgc actggcttca atccatcacg gatatcaggc agtgcacgtt
     9001 cttggataat atatttggaa taacgtccga agcggtcacc catcacttct tctaaagtta
     9061 attcttgtac ttcttgtcga ttttccatca ggtgacctcc tattctactt caaataactg
     9121 attgttttca tttttatctg ctcgttcttc atctaataaa tcattagaaa ctgaaggaga
     9181 gatttcagta tcctcttttt tatctaagat actgccatct tcttcgagcg taaattgcac
     9241 gtgattttcg atccattttc ttcgaggttc tactttgtca cccatcagtg tggttactcg
     9301 acgttcagct tgcgcagcat catcgatacg gacgcggatc aacgtacggg aagtcggatc
     9361 catcgttgtt tcccacaatt gttccgcatt catctctcca agtcctttat atcgctgcag
     9421 catatatcct ttgccgactt ttttaatcat tgctgccaat tcgtcatctg tccacgcata
     9481 ttcaatgact tgcttctttc cttgtccttt ggatacttta tataaaggcg gtaacgcgat
     9541 atatactttc ccagcttcaa tcagcggttt catataacga taaaagaaag taagcagtaa
     9601 tacttgaata tgggcgccgt ctgtatccgc atcggtcatg atgattactt tgtcgtaatt
     9661 acagtcttcg atagaaaact caggaccgac tcctgcacca atcgtataga tcatcgtatt
     9721 gatttcttca tttttcaaga tatcttgcat tttagctttt tcggtattga tgacttttcc
     9781 tcgtaaaggt agaattgctt ggaactttct gtctcttcct tgtttagcag atccgccagc
     9841 agaatcccct tcgactaaat acaattcatt tttcttaggg tttcgggatt gtgcgggtgt
     9901 caattttcct gaaagaagag attcgccttt tttacgcttc ttcccatttc ggctttcttc
     9961 tctggcttta cgtgctgctt ctctcgcttc tctggctttg attgctttac ggaccaacat
    10021 ctggctcatt tcgctatttt cctgcaaata aaagcccatt tgttcactga tgacgttatc
    10081 tactacggta cgagcaactg gcgtaccaag tttttctttt gtttgccctt caaattgcag
    10141 aagattttca ggtacacgga tagaaagtac agcagctaac ccttctctga aatcactacc
    10201 ttccagattc ttgtcccgtt ctttcagcaa accaactttt ctcgcatatt cattataaga
    10261 tttcgtcatc gccgctttca taccagcttc atgggttccc ccatcttttg tccgaacgtt
    10321 attgacaaaa gataaaacat tttctgaata accgtcattg tattgataag cgacctctac
    10381 ttcgatacct tctttttctc ctgaaaaata aacaactggt gtcaatgtat ctttttcttc
    10441 attcagataa tcaacaaatt ctttgattcc ttcttcgtaa tgaaaaattt ccttgactgg
    10501 ttcttctcca cgaagatcag aaagagagat tttaacgcct tttagaagaa aggcagattc
    10561 tcttaaccgt tcggctaaaa tttcatatga aaatttcgtt gtactgaata ttgtatcatc
    10621 tggtaaaaaa tggacagtcg tcccgtttgc tttttttgtt tttcctatct ttttcaaagt
    10681 accgtcaggt ttaccgccgt ttttaaattt ctgctgatac tctacgccat ctctaacgat
    10741 cgttacaatt agccatttcg ataaggcatt taccacactg gctcctacac cgtgcagtcc
    10801 accagaagtt ttgtaccctc cttgaccaaa ctttccgcca gcatgcagca cagtaaaaat
    10861 cacttcaact gttggtattc cggaagcatg cattcctaca ggcatcccac gtccgctatc
    10921 tgcaacagtt atactattgt cttcatggat ggtcacatca atctcactgc cataacctga
    10981 taatgcttcg tcaactgcat tatcgacgat ttcatagact aaatgatgca agcctcggct
    11041 gtcagtggat ccaatgtaca tccctggtct ttttctaact gcctctaatc cttccaatac
    11101 ttggatggac gagtcattgt attcgttgtt tacttttttt gccaaggcaa acgctccttc
    11161 aataatactt tgcggcaaaa ccgcaccacg attatcatac tagaaaaggt cgtgaaaaaa
    11221 aagagggtag acgagaaatc aattttaatt atctcctaac cgctttttcg acattcccct
    11281 ctatcgatca tctcttcttt gtggtcattt ttatttttgg ttttctttca acttaccaag
    11341 ttcaatctta atacaacgat ccattacgat atctgtacgt cctgcttttc ttagcatctc
    11401 agctgcttct ttgttttcaa tccctaattg tgcccagaac actttagcat cagttttcaa
    11461 aaaatcacct gctatttcag gtaaaaattc actccgtcta aatacatcta cgatatcgat
    11521 tggatcatcg atttctgtca aattcgcata gactttctcg cctagaattt cttcaccagc
    11581 caataatgga tttactggta tgattttata tccattgtct tgcaatacct gtgcaaccat
    11641 gtaacttgtt cgttctggtt tattgctcaa gcctacgacg gcaatatttt ttgcttcttc
    11701 caaatagttg aaaatcgttt cttgtgttgg attttttaca gacatttctg ccaccccttg
    11761 cttttctttt tattccatct attatacttg tatctttcat tttttcaatt gttcctgtta
    11821 cctattcatg ctaaaataaa ggatagtttt caacttgaaa gagggtaaaa aatgaaattg
    11881 atcttattac ttattttagc atatctttta ggttctattc cttccggtgt ctggattggc
    11941 aaattgtttt tcaaaaaaga tatccgacaa cacgggagcg gtaatactgg aacgaccaat
    12001 acatttcgtg tattaggcaa aacagccggg attgttgtcc tgcttatgga tattttaaaa
    12061 ggtacattgg ctacttgttt gccgatgatc ttccaccttt ctgggattaa ccctctttgg
    12121 tttggggtat gcgccattct tggccataca tttccgattt ttgctgggtt caaaggagga
    12181 aaagctgttg cgacaagtgc aggaatgctt ttaggattta atcctgtatt ttttgtttat
    12241 tcttgtatca tctttatcgt tagtttattt tgtacaagta tggtgagttt gagcagtatg
    12301 atcagtgcag tattgatcac tttatctacg atcgtccttc cttatgtagc tcctgtgatt
    12361 ttggctaagc ccaattggtt actgacgatc attgcctttt tagtttcttc ctttatcttt
    12421 tatcggcata aagacaatat caagcgtatc agaaaccata ctgaaagtcg aatcccgttt
    12481 ggtttgaata gcagcaagaa aaaatcctga tactttttca ttccaaagag ataaaacggg
    12541 agtgtgacaa atcgatgtca cactccctta ttacttacag gatagctttt ttacacacct
    12601 tggtaaacgg tgttccctgc taacttctcg gtcacaacct cttacttcac tgtgatggaa
    12661 tattttgtct tgaagatttc atgggcacct agttgattga tccctacttt ttccatcaag
    12721 tttccactac tgttcaccgt gtcagcgatt ccgcaccacg gttcgataca aacgaaaggc
    12781 gcttcttttg gataaggaga ccagatccct acataaggca tatctttata gcttaaagtt
    12841 acgctatggg aagatttttc acttcgaatg gcgtacgcat ttagacccct tgtttcaaaa
    12901 accaaggcat cttgctcaaa aagttcacga ttcaaagcca gattcgtatt tgtctgacct
    12961 aacgtctttt gatccatatc gatgaatggg cctttcaatg gtaggcgtaa tcttgatttc
    13021 aatggagaaa atgccagata gaaatcttca aatgacaatc cttcttcaag aggtacattg
    13081 aaagcaggat gtccaccgat agaaaagaac atttcttttt caccggtatt tgccacttga
    13141 taatgaaccg tgatgccgtc tcctcctaat tcatagctga tcactaattc aaaatcaaat
    13201 ggatactttt ctaatgtctc cggcgtactc cttaagatga aactagccat ttcttgtcca
    13261 tgttcaatga cttcaaaatc catatcccga gcaaatccgt gttgccccat ttgatatgtt
    13321 ttcccttgat aaacatactg atcatctttt aaacgtccaa caaaagggaa taaaaccggt
    13381 gcatgtctgc cccaatacgc tggatcacct tgccagatat actctaaacc atgttctttt
    13441 gatttcagac tgatcaattc cgcaccgtgt tcagcgattt cggcgatcag ctggtcattt
    13501 tgaataataa cagtcattgc cattcctcca acttcgactt actttttaaa atgggaaggc
    13561 tggaacaaac atttctatct gccccagtcc ccttacttct aataactgtg ttttgctaac
    13621 tcgtctttaa aacgggaatt caatactttt aaataagttc ccttcatgcc taacgaacga
    13681 gattcaatga ttccagctga ttccaatttt cgtaaagcat tgacgatcac agaacgagtg
    13741 atgccgatac tatcggcaat attagaagca gtcagacgac cttcatctcc atccaatgct
    13801 tcaaagatag cttgtacagc cttcaattcg ctataagata atgtgttgat tgccatttgg
    13861 acagccgttg cactccgtac atctgcttcg atgcttcgag acttctgata aaggatctgc
    13921 ataccgacaa ccgtagctcc atattctgct aagactagat cgtcatctgc aaacgattgt
    13981 tccatacgag ataagataat cgtacccaaa cgttcgccag ctccaaagat cggaacgaca
    14041 gtcgtcagac caaatggata tttctctctt gactctaccg gaaatgcagt aatatcacta
    14101 gtaattggga tattagcttc agttttcatc aactgtgcca ctgtatcagt ataagattca
    14161 ggaaattgtt tctcaacaaa cattgttttg attcgttcat tgttcacatc gtgacgttca
    14221 ttataaccta gtaatactcc gtcacttcct atgatatagg tgttgctgtc aagaatacca
    14281 cctagtgtga cagccatttt atcgtaaggc aaatctgctt gcatgtcaaa agtattcttt
    14341 tgctgcaaaa gtgtgtttat cttgcgggtt ttcgttagca agtctgtcat tgtcgtcctc
    14401 cgatttttta taaaatatag cgacttaaat cttcatttgc cgcaattgag ccaagtttgt
    14461 catccacata tgcttctgtg atcgttattt ctcccatttg catatctggt gcttcaaata
    14521 atagatcttc tagtagtttt tccaaaatgg tatgcagtct gcgtgcgccg atattatctg
    14581 tgtcacggtt gacatcgaaa gcgatttgag cgatccgttc aattgcttct tttgtaaacg
    14641 taactgacac attttctgta ccgatcaacg cgacgtattg ttttactaaa gcattatttg
    14701 gttcggtcag aatcttcaca aaatcttcag ctgtcaaatc atctaattct acccgtatcg
    14761 ggaagcgtcc ttgaagttct ggaattagat cacttggttt agacaaatgg aaagctcctg
    14821 aagcaatgaa taggacgtga tctgtttgga tgatcccgta ttttgtgttt acttgtgaac
    14881 cttcgacaat tggcaatatg tctctttgga cgccttctct ggatacttct ccagattgct
    14941 gtgatttaga agtgatctta tcgatttcat cgataaaaat aattccactt tcttccgcta
    15001 atttgattgc ctcactatgg atatcagcat ccttgactaa ttttgctgat tcttccttga
    15061 tcaataactc taaagcttct ttgactgtta ccgtccgttc cacttttttc ttcggtgtca
    15121 aagcacctag agtttcattt aggtcgatcc ccatttgctc caatccattg ttcatcattg
    15181 gtgcaggttt cttttggtct tcaacttcaa tggttacttc acgactatcc agtaaaccct
    15241 tttgtagttg ttccaagact gtacggcgat tgattcgaat atcttctgtc acttcttctt
    15301 gcggttcagc ggtattttgc tgactagcat taaaaagatt catcatttgt tcaaattgat
    15361 tagtggattg tttctgttct tttttgatac caggtaccaa gatttttacc aaacgttttt
    15421 ctgcattttt tttagcactt gtgtatacac ggctgtactg ctctttttct acgatttgga
    15481 tcgcattttc tactaaatcc cgaaccattg attctacatc tcttccgaca taaccgactt
    15541 cagtaaattt tgttgcttcg actttgacaa atggtgcatt gacgattttt gccaaacgtc
    15601 gtgcgatttc tgttttaccg acccctgtag gtccgatcat cagcatattt tttggtgtaa
    15661 tatcttgttg cattttttca tctaactgca aacggcgata gcggttacgc aaagcaacgg
    15721 caacagattt ttttgctgcg tgctgtccta cgatatattc atctaattca cttacgattt
    15781 gtcttggtgt ttgttttaat tcatacatat ctactcacct cttacagttc ttctacgata
    15841 atattatgat tagtaaagat acagatatct gcggcaatat ttaacgcatt ttctgcaatt
    15901 tctttcgcac tcatgtcgtt ttgagcatag tttttcattg ctcgggctgc agccaacgca
    15961 aaattccctc ctgatccgat agctaagata ccatcatctg gtgtgataac ttctcctgta
    16021 cctgaaacaa gaagcatttc tttatcattc attacgatca gcatcgcttc aagtttttgc
    16081 atagattgct gtgtccgcca ttcttgagct aattcgacag ctgcgcgttg tagattcccg
    16141 ttatattcgt ttagtttgcc ttcaaatttt tcttctaaag taaacgcatc tgcaacactt
    16201 ccggcgaaac ctacaacaac ttctccattg tagatacgtc gtactttctt tgcagtgcct
    16261 ttcatgacaa cagattcacc cattgttact tggccatctc cagccatagc aaatttcccg
    16321 tctttttcga cggcacagat agtggttgaa tgaaatggtg attcgaccat gtttgtttcc
    16381 tcctaaattt gttcttttcc ttatttttac gctcttggat ggaaagaacg atagtttttt
    16441 tgtaaacttt cttttgttac atgggcatag atctgggtag tcgataaatt ggcatgtcct
    16501 agcaattctt ggactgtccg caaatctgcc ccattattta ataaatgagt agcaaatgta
    16561 tggcgcagca tgtgaggatg gatatcacta tccaaactgc tttttttgat catttgattc
    16621 aagacatatt caattccagt aggcgtgatt ggttttccat gatgattcac aaaaacgata
    16681 tcatgctctt cgtgatattt tgtcatcaat acctggcggc cttccctgaa atattcttgc
    16741 agagcatctt gagcaaaaga acctagagga gcatatctct ctttgttccc tttaccatgg
    16801 atcaacatga cctctgaatc aaaatcaatg tctgataccg acaaactgct acactcactt
    16861 aaacggatgc ctgacccgta aaggacttcc agtaaagcgc ggttcctcaa atccaaagga
    16921 ctatctcctg ctacgctgtc aaaaagtgct tgcatttcat tttcataaaa aaaacgtggc
    16981 agtctcaaat ttttcttttt gagatgaacg taagaaaatg gattttcttt tatcacttct
    17041 tctttgagaa gatactgata aaacgaacgt aggctggcta tcttgcgact gatagaattt
    17101 ctgctatagc taggacgatg atcagctaat gcactcaaat agacacgaac cgtaaaatat
    17161 tccgccttca gcagatcagc gtctccagat tcctccaaaa aatgtttgaa atggagaatg
    17221 tcttcttcat atgcttcttt cgttttttct gaatatcctc tttcgacaat caaataacgc
    17281 aaaaattttt gttcccacgt ggcttctgtc attttctcac cttccttttg tcccagagaa
    17341 taatttagca cagcgtttat aaaaagacaa ataaattgtc agaatttaac caatatttct
    17401 aagtttgttc acaattggcg caattcctca cattttgttt gagaaattct taagaaaaac
    17461 gcaagaaaaa gagcgagact atccgtctca ccctcttcat ggagtttcct tactcatttg
    17521 ggattgcagt tttttctaat tctgttttta ttgcctcatt agcttttaaa gctcgttgtg
    17581 caattgcttc atatcttgct tttttgtctc gaatgcgctc tggcagttca ggaaacagac
    17641 catagttggc attcatcggt tggaaatgtt ttccttccgc atgagtaatg tagtaagcca
    17701 tacttccaat agctgtttct tgtggaaact cgactggttc catttctttt gctaagcgtg
    17761 cggcgttgat tccagcaagt agtccgctcg ctgcactttc aacatagcct tctacaccag
    17821 tcatctgacc tgcaaagaac agatcttcgc gtttcgttga ttggtaagtc ggtttcagca
    17881 attctggcga attcataaag ctgtttcggt gcatcacacc atagcgaacg aattcagcat
    17941 tttctaaccc aggaatcatc cggaaaacac gtttttgctc gccccatttc aagtgagtct
    18001 gaaagcccac gatgttgtat aaagaagctg cagcattgtc ttgacgcagc tggataacag
    18061 cataaggacg tttgccagtt ttaggatctt ccaatccaac tggtttcata ggtccgaaaa
    18121 gcatcgtttt gaatcctcgc tgtgccatta cttcaattgg catacatcct tcaaaatatt
    18181 tttctttctc aaaagattta agttctgcca cttcggcatt gattagtgcc tcatggaaag
    18241 ctttgaattc ctcttctgtc atcggacagt tcaagtaagc tgcttctcct ttgtcatagc
    18301 gggacttcaa atatacttta tccatatcga tcgtagcttt gtctacgatt ggtgcagctg
    18361 catcatagaa ataaaaacca tctgaaccat tgaatgcttt gatgctttct gctaatggat
    18421 gagaagtcaa aggtcctgtt gctactacgg tgattccttc cggtatttca gtaatttctt
    18481 cgtttatcac tgttactaat ggatgctctt tgacttttcg ggtaattgtt tcagaaaaag
    18541 aatcgcggtc aacagctaag gcaccaccag ctggcactgc tgtttcatct gccgaagtga
    18601 ttactaccga attcaatcgg cgcatttctt ctttcaataa ccctactgca ttagccaaac
    18661 tgtttcctct taatgaattg gaacatacta gttcagcaaa attacttgtg tgatgcgcct
    18721 cagtcgattt gactggacgc atttcatata aacggacagg gactcctgct tgtgcgatct
    18781 gccaagcagc ttcacttccg gcaagccctg ctccaacaac atttaccatt ttcaatgaaa
    18841 gaacctcttt tctattattt ttggatgtct tcttcgtaat ctccatttac acagactact
    18901 tgtttaccgc ctttgacttt cttctcgacc agatatccgt cacattttgg acaatttctg
    18961 cccactggtt tatcccaaga agtgaattca cattctggga aacgggaaca accatagaat
    19021 agtctgtttt tcttagattt tcgttcaatg acttgtcctt catgacatac tgggcaagtc
    19081 acaccgattt cttttacgat tggtttcgta ttccgacaat caggaaaatt actgcaagca
    19141 taaaacttcc catatttccc taattttatc accatcggat gtccacagac atcacaatcg
    19201 aatcctgctg gttcatcttt gatttgaatt ttttcgattt tttcttccgc attcgtcagt
    19261 tctttttcaa acggtttata gaaacgatca accactttga cccacgcttc cgtgccttct
    19321 tcaattttat ccaaatctcc ttccatttct gctgtgaaat ggatatcgac gatttgaggg
    19381 aagaattcac agattaatga attgacaatt tctcctagtt cagtcggctc aaatcttttt
    19441 tgtgtcaatt ttacatagta gcgtctttgg atcgtatcaa gtgttggtgc ataagtggaa
    19501 ggtcgcccta ccccgttttc ttctagtgca cgaatcaacg tagcctcact aaaacgtgct
    19561 ggtggttgag taaaatgttg ttttggttca atatcaacag attggactac atcgccttct
    19621 tcaagttctg gaagaatatt ttctttctct tctttgccgt catctctacc ttccacatac
    19681 acttgcatga atcctttgaa tttgattttt gaaccgttcg caatgaagat gacaccattt
    19741 tgttctaatg tcactttcat tgtatctaaa atagctggtg tcatctgact agccacaaaa
    19801 cgtgaccaga tcaatgtata aagtttcaat tgatctttat ctaaatattg tttgagttca
    19861 tctggtgtac gaagcacact cgttggacgc acagcttcat gggcatcttg tgcgccttga
    19921 gcatttttga tctttcggtg atcatgtcta gaaaattctt ttccatacgt atcttcaata
    19981 aatgctgcgg cctctgcttt tgctgtatcg gcaatccggg tagaatcagt acgcatgtat
    20041 gtaatcaagc cgactgttcc ttgtttaccc aaagtgattc cttcatataa ttgctgtgct
    20101 accatcatgg tttttcttgt tcgaaagttt aacttacggg cagcttcttg ttgcaggcta
    20161 cttgtagtga aaggattcgc agggtttctt ttgcgctctt tcttttctac ttttttaact
    20221 tcgaagtctg ttccatcaat tctagcagtg acttctttta cactttgtgc atctggtaat
    20281 ttctttttct taccgtcgat tccccagaaa tttgctttga atttcttgcg agctttttta
    20341 aaattaccgt cgatgctcca atattcttct ggaacaaatt ctcggatctc tttttcacgg
    20401 tcaataataa tttttaaagc gacagattgg acacgtcctg cacttaaccc tttcttgacc
    20461 ttacgccaga gaataggact gatcgaataa ccaacgattc tgtctaaggt acgacgagct
    20521 tgctgtgcat ctactaaatc tacatcgatc gttcttggtt ccttaaaagc tgctttgact
    20581 gcgtcttttg tgatttcatt gaagaccacc cgattttttt ctttcagatc caacccaagt
    20641 aggtacgcta aatgccaagc aatcgcttct ccttctctat ccgggtcact tgccaagtaa
    20701 actttttgag ctttttttgc tgcggctttc aggcttttga tgacatcgcc ttttccgcgt
    20761 atagaaatat aatggggttc ataattgttt tcaaaatcga tacccatttt acttttcggt
    20821 aaatctctta tatggccaac actggccatt actttatagt ttcgtccaag atatttctca
    20881 attgtcttgg cttttgcagg tgattctaca atcactaaat atttatacgc cattactgaa
    20941 tggactcctt tccattgtcg tgttcctact attaaaagag gattcataca aatcgtagct
    21001 aatcatatcc attcagaaaa cgtttgtcaa gaaaagcaaa tgaaaagtat ggtgttattc
    21061 tttaaattct gccaagatat cttcacccga aaccgtgcaa actgcaccgt cttggatcaa
    21121 atgatgacat ccggtagaat gttctgttaa aatatttcct ggaacagaaa aaactgttct
    21181 tccaagatcc aatgcttgct gtgctgttat cagagagccg ctttttttct tggcttcaaa
    21241 gacacatgtt cctttagaca aagctgcgat aatccgattt ctcattggaa aacaatgctt
    21301 tttcgggccg gattgaggag gatattcact caaaagaaga tgatcatttg caatcacctc
    21361 ttgcaagtca cgattttcag caggatagac ttgctctatc cctgttccaa tgactgcgat
    21421 tgtccgtcca ccatgagaga ttgctgcttg gtgaccgtat gtatctatcc ctttcgcgca
    21481 gccactgacg atcacatatc cagcttctat cactggtttt agtaaataat aaactgtttt
    21541 tttggctaaa gcagaagtgt gtcttccacc aacaacgctt aacatgttac aagaaagtaa
    21601 agatagatca ccattataaa acagtacaat tggcggatag gtcaagtgaa gcagctgagg
    21661 gggatatttg ggatcaaagc aagtgataaa cgactgtttc gattggattt tgccccagtt
    21721 agcgtgaatt tcctgccaac ttttgcgaaa cagctcccgg tgtttggtta ttttacctat
    21781 cttaatgatg tcttcaaatc cgatttcttt ataaggatac tgcatcatcc agttagcaag
    21841 tgcccatttt ccttgactac tgattccttt tgtataagca agtttcaata aattttcttc
    21901 tatttgatac atcataaaac cgcctttcgt ctctctttct aataagatac gtaaaagcgg
    21961 ctgtttttta ttgtaaatat ttttttacag gtgcaaaact tttacgatgg attggcgtaa
    22021 ttccttgtcg ttcaagtcct tctaagtgtt cctttgttcc ataacctgca ttatgcgaga
    22081 aaccatatcc aggataaagc acgtcatatt ctttcatcaa ttggtctcga tatactttag
    22141 caatgatact tgcagcagca atcgacacag atcgtgcatc ccctttgatt attttttcct
    22201 gctgaatagg caaatccaag gtcatcgcat cgatcaacaa atagcttggt acaatggaca
    22261 atttttctac tgcttggatc atcgctaatt tacttgcttc ataaatattc acatcatcga
    22321 ttgtctgctg atcaacgatc ccgatcccga ttgccagggc tttttcttga acttgttgat
    22381 aaagaagttc tcgctttttc tctgataatt gtttggagtc attcagccct aatatgatct
    22441 catttttcgg caagataact gcagctgcca cgacaggtcc agctaatggt cctcttccta
    22501 cttcatcaat gccggcaatc cattggtgac cttgtgcgta cccttgcttt tcaaagcaaa
    22561 acatttcttc atatttttcc ttaattaatg cttccttttt caatcgtcgt tcaaaagaag
    22621 ccagtgcttg ctgcacgcct ttgcgtggat catttcttaa tgattctagt gtaggatcat
    22681 ctattctctg tatgcttttc aatcgttctt tgatactttg gatggattca gtcatcactt
    22741 ttttgctcca tttcttcgca acgatccagt gtgtatcgtc caagttttcc ttgacgaata
    22801 tcatgcacga ctaattcgct gccacgatca tagtcttctt tatacccacg ttttgctgta
    22861 atatccatca gtaattccgg tgccaatttt tcttcttgct cgattgataa accataacga
    22921 tcgctgattc ttcctgaata atatcgggca aaaaagtcta atccgtaaat cgctaaatca
    22981 tctaaatgga caagctggtc tttgatcgcg cctgtcagcg ctagtttttt gccgatttct
    23041 tcatcttcaa atttgggcca taaaatccct ggtgtgtcta acaattccaa ctcattacct
    23101 aaacgaagcc actgctgacc ttttgttacg ccaggcttat ttcctgtctg tgcaattttc
    23161 ttgcctacta gtcgattcat caacgtagat ttcccaacat ttggaatacc taagaccatt
    23221 gcccgaatag cgcgaggctt gatcccccga gcagcatctc ttgcccgttt ttctttcaat
    23281 gcttctttag ccgcaggtac tagaccttta attcctttac tttcttgtgc cgtgatagct
    23341 aatgcaagat ggccttgttt acgaaaatat tcttgccaca gctttgtctg ttgtggatct
    23401 gccagatccg ctttattcaa taaaacaagg cgaggttttt gctgaatgat ctgatctagc
    23461 attggattac gagaagataa aggtaatcgt gcgtctacca attcaaatac gatgtccaca
    23521 tatttcattt tttcagaaac ttctcgtcgg gcttttgcca tatgtcccgg aaaccattgg
    23581 atggtcattg ttctctccat tcctttcata ccggaatatt ccccggcttt acttgttttt
    23641 ttctttttca atataaattc acttttttat tataaagaaa ttccatctat tagttaagtg
    23701 aaagtgaacc agtcctcatt ctatcacatc ttcacttttt tgatgatgca aatttttatt
    23761 ttggtttcta tatatgaatc taaatttttg acagcgtttc ctaaataaga gatgatagac
    23821 gaacaaaaca gaaaggagac gaaacaaatg aatagtatgg tttttgttaa ttttcctgtt
    23881 gctgatgtca atcgttccgt tgctttttat gaaaagctgg gttttaaaaa aaatgaagaa
    23941 ttttctactg aagaagctgg ttcaatggta tgggatgaca ctttttggat aatgcttctc
    24001 tctcatgatt tttataaaaa atttataaaa gataaagaaa tagctgataa taaaaaaaca
    24061 agtggtgctt tgatttcgtt tagtgttgaa aatgcggatg aagtaaaaaa atttgctcaa
    24121 attgcaaaag aaaatggtgg tactttccac gaagtagata tgggaatgcc tgaagaagaa
    24181 atgttttcat tagaagtcca agatctagac ggaaatacat tagaacccgt atggatgaag
    24241 atgtaagcag ataactaatc tgacgttttt tataacaaaa aaacaaaggc ggatgatacg
    24301 ataagtattc tccgcctcta ttttttttat tcgtacaatc tcttttttac agtttataaa
    24361 agcagtcttc tcaccctttt tttaattgtt agatgccagt gtatgtaaat caccaatgtg
    24421 tcatgacaca ttggtgattt tatggtatcc ttttattatt aactgacaaa ggagagaata
    24481 ttttgaacac tttgattgca aaagacgttt ttagattgcc cgaaatgaat gcaagattgt
    24541 tgtcgacctc tgctctttta ttagcccttg atgtcatctt atacaagata gcgattggtc
    24601 ctgcttattt tcaaatcaca ttcggatttt taagtatggc gcttatgggt tatctatatg
    24661 gaccgatctg ggctggtttg cttgaaatgt tgtcgaacac tttaaatttc acgatatttg
    24721 gttcaggaac gtttcaagct gcttttctta tcacggcttt ccttggtgga tttattaatg
    24781 gcttattttt atatcataaa aagataaacc tgccttccgt catcgctgcc caattattga
    24841 ttatgatccc agtcagcctt tttatcaatt cttggctgat gtctgttttg tttggtgcag
    24901 atttcaaagt aatttttcta ggtagattca tcaggaatat gatccaaatc cctattcaaa
    24961 taatggttgt ttattcattt atcaaaactt tagaggctag aaaagtgttt aaacgagctg
    25021 tttgatttta cgtactaagg tagtaaactg attttggatt aaacaataaa gcgtgcagtc
    25081 tcaacagact gcacgcttta ttgtttctca ctggatccat tttatttcat caagtggata
    25141 atagacaaat cttgctttac ctagaatatc agttttattg atcgtgccaa acgaacgact
    25201 atcttttgaa actcttcgat tatctccaag tacaaaataa ttatcttccg gaagcttgga
    25261 ttgtcccgtt agctcttgta gtgtaaagtc cgtcgtatag gatgcatttg catgatctga
    25321 tttcaggttt ttagttagat aaggttcctt aactactttc ccattgatct tcaattgatc
    25381 attttggtag ctgacatttt ctcctggaag accgattact cgtttgatat aaatcgtgcc
    25441 atctgctaat tgaaaaacaa caatatcaaa tcgtctgatc tccgaaaatt tttccatcac
    25501 aaccatatca ccttgcttca acacgttttc cattgaattg ccttccactg gtaccgggat
    25561 gaataaaaat ccccgcaaca tgaacgcaag gaatacagaa acaagtaagt atttgaatac
    25621 aagccagaag cgattaatat agcgttgttt ttttgtcaat ctctatcaat ccatccctct
    25681 ttttttcatt ctttctttat tataagaaaa atatcaaaaa aatgcgacta gatagctgaa
    25741 ataaaaataa ttctttcaat taggctattg gacaaaaaac ttttttgatc ataaagtaca
    25801 aaactatctc ttatatgtca tgattatttt ctaaatattt ttcccatgct tcgtcaaaga
    25861 tatccatgga cggcaaatag tcgacattca gttccagata attagaaatt tcttcgtagc
    25921 tagagctgtg cttaggaaat tggatgtctt taccggcttc tgtagcgaaa acagataaag
    25981 catcatgtgt gccaccgcct cgcagtgtca ttaaataatg aaaaaagctt cgattcaccc
    26041 ttcgttcctc caattttctt cgataaaggc agcccggcgt gcatggtttc ttttaaaatt
    26101 ttcaggatgc tttttataat actcttgatg gtcttcttct gctagataaa atggttgggc
    26161 tggttcgatt tttgtaacga ttggctgttc gaaacgtcca ctttcagcta actgtttctt
    26221 acttttttca gcaatgatcc gctgttcttc tgtcaaataa aagatcaccg ggcgataatt
    26281 gtcaccgcga tcctcgaatt gtccgaaagc gtcagttgga tcagtttgct gccagtaaag
    26341 ttctactaat tgttcatatg aaatcaatgt tggatcatag ataatctcca ctgcttctgt
    26401 atgtccagtc gtttggcttt ttacttgttc ataagtcgga tctggtacat gccctccagt
    26461 atatcctgac atcactgtat ggataccagg aagcgtgtcg aaaggctgga tcatacacca
    26521 gaagcagcct cctgcaaata ttgctcgttc cattatgatt ccccctctaa tactactcat
    26581 ccgatgattt tttattttct tttgtcttgc tttcagtact gctggtgcta gttttgttgg
    26641 tatttgagtt gtttgaagca tcagaggtat cttttggcaa atatagacta aaccgaatgt
    26701 catcatttac taagtcgatt ttatctgctt taatatacat cccgttttgc attcggaatt
    26761 gatccaacct aagcatgata gtcagatcat ctgtattgac ttcgatccaa tctggtaatt
    26821 tatagtttct cttgatcata ttcatcacat ctttgattgg caaactcaat gttccgatag
    26881 aaagacttct agcttttagt tggacatttc cgttttccat cacatacgga tcaaaatata
    26941 aatagaaatc gataggaaaa cctagtactt cgaaagtacc attgagtagt gcttcatttt
    27001 ccaaataaaa tttatattca atatcactat ctttttgata ctcactaagg aaaaagctga
    27061 tgatttgatt gactttttct ttatttgaat tgatcgttaa gacaggatct ccttgtcttt
    27121 ccgtaagagc tggtatttct gggagttctg gttcccgatt agcaaaaata cggctgccta
    27181 aaaatacggt cgaaccaagt actaccccaa gaaggataag gaaggcgaat ttccagtaat
    27241 ttgttttctt tgttttgttt gaagatacgt cagatcttgt tttcatgttt attgatcatc
    27301 ctccttctct aaccattggt tttgtgtctc gatcagctga tctctcactg catttgccat
    27361 caattgataa cctaaattat ttggatggaa atgatcttct tcatagagca cattattttt
    27421 gatgccattt agattttctg tcgtgctagt tgtttgatct gttccttctt ctgtgacacc
    27481 tacttcctga ttcaatcctt gataaagcaa atcattgatt gggataaagt agcagttcgg
    27541 catttttttt gtcaccgttt ctgttccttt gttccaattg ttaacaattg tctgcatgtc
    27601 agtgatctca ggaaagttca aataaaatgg attgtagatg cctaaaatgt aaataggtgc
    27661 ggttttattg agggatcgaa attcttccaa tagttctgtg acattttcct gatagttttt
    27721 cagtggcttt ttaaaggaat tgaccgttaa cccgaataaa ttattttgga taactttcat
    27781 caaatcatta ccgccaacag tcagtgtgat aaaatcagct gttttgatat tgtttcgaat
    27841 ttcttctttt gtttttactc gctttaagat ctggtcactt cgttcaccat ttacaccata
    27901 gttttctgtt tcaaccgcgg tcaaattata acggtctttt agatcatttg cgacaagggg
    27961 aacgaatcct ccttgcttgg tttgatctcc tactccttca gtcagcgaat ctccgatagc
    28021 tatgtagtga agtttttctt ttttatttgg atcttctctc acagtagtta ctggtttcat
    28081 tagtgggcca gctttcggta tagaagcagc taaacctgca tagatgatga tcgcaattaa
    28141 taatgggaac aaaacgagga tcaaatgtcg tttcgttaat ttcatttttt cacctcttgt
    28201 attcgattgg ttctaatgtt atcaaaaatt ttatcaaaaa ggtagtcttt atgaaaaaag
    28261 aaaacaatta ttttcctaat tttataaaga aaaagagaat aagctgcaag cctttcaggc
    28321 tgagggctta tcctcttttc gactaatcta cataatacat gattgcaaac gcgtctttac
    28381 cagtatgcgt agcgataacc ggattcgtat gcagtacagg gatatgcatg tccgggaata
    28441 attcttgcaa accctctttg aattcttgcg ccaattcttt tgcatccgca tgtgaaatac
    28501 cgatttgtcg cacatttggc aattctttca gttcattttt caaattatta aaccatttat
    28561 cgaacgtttt ctttcctcgc cccttagtta cagggattaa ttcagaatgg gcgaaattca
    28621 tcaccacgcg tatgttcaaa acactagaca gcaaaccagt tgttcggctg attcttccac
    28681 cttttaccaa gttatctagt gtggatattc cgatgtataa ttttgtattg tcttgtactt
    28741 ttttgacttc ttcaaggatt ttctctactg ttttaccttc ttttgctaat tcagctgctc
    28801 gaattacctg aaaagataat ccttggtcag tggtatcact gtcgataacc gttactttcg
    28861 tttttgttag attactggct tgtcttgctg cttctactgt tccactcaag ccttttgtca
    28921 tatggatcga aatcacttca ctgccgtctt ctcctagctc atcatacatc gagatgaatt
    28981 ctccaattgg tggttggctt gttttgggca gattttttgc tttcgccatc atttccataa
    29041 atctttcgcc gtctagttgg tcatcatcgg gatatactgt tccgtcgatc atgatggata
    29101 gcggcatgac acgaatgcct aaagcatcgc gtacattttt ttccatcgta catgaagaat
    29161 ctgttacgat ttttacattt gtcattattt tctctctctc tttctttaac aagatgcctt
    29221 attcatgtta aactacatgt aagacaattt ctatttttag tataacagac aaataatgat
    29281 ttttcattaa ttacacctag taaaggagcc gttttcatgg aaaaaacgaa atttaatcga
    29341 acgtatgaaa tattaaatga agtgtttaat gcagtcaccc atggaattgg gactggattg
    29401 agtatcgcgg gactagtggt tcttttagta aaaggtgccc acttgcattc ctccctccat
    29461 attgtctctt atgctatcta tggatcgatg atgattcttt tatttttaac gtctactttg
    29521 tttcattcat tgatttttac aaaagcaaaa aaggtgttcc aagtattcga tcatagttcg
    29581 atttttcttt tgattgcagg aagttatact cctttttgtt tgctgagtat ccgaggatgg
    29641 ctaggttgga ctttatttgt attaatctgg ttgtttgcga ttcttggcat tatatataaa
    29701 gcgttgacgt tgcataaacg ggagagagta tcaaaagtat ctacgatcat ctatattttt
    29761 atggggtggc tctgtgtcgt ggctgctgtt cctctttatc actctcttgg aatgactggt
    29821 gttattttga tggtagcagg cgggctttct tacacgatag gcgcattctt ttatagcttg
    29881 aattctatcc gctatatgca tgttgtttgg catttgtttg ttatgttagg tgcaggtttt
    29941 atgtacttct ctgttttatt ctttacttaa taaaaaaaat aaagctatgg atgggacagc
    30001 tctaaataac agctagtcta tccatagctt ttttatatcg tcaattcgcc tgtcccgctt
    30061 tttacaggat tctcattacg ctgatacgtt tcaaattgat gcggataacg atttttttca
    30121 tccatttctc cttgactagt attgatcagt gaccaatcag accagtcaac aggtggaaaa
    30181 taagcatctc catcgaatac atgatggatg actgtacggt ataatatcgt acaaaatggc
    30241 agaaattctt gataaacagc tgaccctcca gcgatgaaaa agataccgtc tgtttctttt
    30301 tccagagcaa gcacgtcttc cacactatgc atgacatgca cgccttctgc tttataggaa
    30361 gaatctctcg tcaaaacaat cgtctgacga ttcggcaacg gacggctacc catcccttcg
    30421 aatgtttttc gtcccatcac tagtgtattt gcttctgtca tttgtttgaa gaatttcaga
    30481 tcatttggca aacgccaagg aagacggtct tcttttccaa tcaatccgtt ttcatcctgt
    30541 gcccaaattg cagctaacat tttctcatcc tttctgattc taaacagcga taggagcttt
    30601 gatcgccgga tgtgggtcat atccttctaa ttggatatct tccatctcaa aatcaaatac
    30661 tgactgcttt tcctgattca aaactaaagt cggaaatgcg cgtatttctc ggctcaattg
    30721 ttctttcatt tgttcgatat gattgatata aagatgagca tctcctaatg tgtgaacaaa
    30781 ttcgccaacc gctaaacctg tttcatgtgc aattaggtga gtcagcaacg cataacttgc
    30841 aatgttgaac ggaacgccta gaaacacatc cccactgcgt tgatacaatt ggcagcttag
    30901 ccgtccctct tgaacataaa attgaaacat cgtatgacaa ggaggcaaag ccatgctagg
    30961 aacatcttcc ggattccatg cagaaacgat caatcttcta gaatcaggag tctttttgat
    31021 tgcttcgatc acttgtttga tttgatcgat aaagccaccg tcttttgttt cccagtgacg
    31081 ccattgatag ccgtagatgt gtccaagatc gccgtatgtt tcagcaaagg aatcatcggt
    31141 taggatcttc tcgcaaaaaa gcttgctctg ctttttatat tcttcattga attcaggatc
    31201 tgtcaaacat ctatggccaa aatcagtcat atctggtcca ttatagtctg gacttttgat
    31261 gtagcgttca aatgcccatt catcccaaat atggttttta ttttgtaata gatagcggat
    31321 attcgtatct ccttttaaaa accaaagcaa ttcgcttttg atcaatccaa aaggtactcg
    31381 tttcgttgtt aacaaaggaa accctttttg cagatcaaac cgcatttggt atccgaataa
    31441 gcttaatgtg cctgtgcctg ttctgtcttc tttacgatgc ccttcttcca acaattttct
    31501 tcctaagtca agatacgctt gttccatcct ttttcctcct aatcttctac ccattcactc
    31561 aagtattccc accgtgccat tttttcttca agttgtgctt ctgtttcaga tacgtcgttt
    31621 tgcaattctt gtaatcgagt gaaattatct ccttgatgat tcatctcttc ttggagcaat
    31681 gagatttttt cttcaagttc tgcaatctca tcttcaatcg tttcccattc tttttgttcc
    31741 atgtaagata atttcttctt ttcagcaggt tccttgctct gtatttttgg tttcgctttt
    31801 tcagcaggct gctgggtctc tttttgcttc agtaaataac tggacatgtt tccgtaataa
    31861 agttcttgtt ttccgtttcc ttggaatact aataacttat ctgctacctt gtccaagaaa
    31921 taacggtcat gggaaacagt gatcacagca cctggaaaac ttctaaaata atcttccaaa
    31981 atcgtcaatg ttgctatgtc caaatcattg gtcggttcat ccaataataa aacattaggt
    32041 tgctgaatca gcagtttcaa caaaaataac cggcgttttt ctccgcctga aagtttgcct
    32101 atcagtgtcc catgcataaa tcttggaaat aaaaatcgtt caagtaattc tgctactccg
    32161 atttgactgc catctgctgt ttttgcttct tcagcagctt cttgtaagta agcaatcatc
    32221 cgtttatctg gtgccatttc ttcattttct tgtgtataat acgcaagatg aaccgtttca
    32281 ccgatagaca ttgtaccgct atccagggga attctgccag ctagaatatt aagcaatgtc
    32341 gattttcccg caccattttt accagtaata cctagtcttt cccgagattg aatcaataaa
    32401 tctaaatgtt ctagcagtgt ttggtcattt atacggtaac tgccatcttt gatttccagt
    32461 acttttttcc ctaaacgttg tgtcgctagg ttcagctcta aatcatcttc ttggtttact
    32521 tggtacaagt tctcctttag atcttcgaaa cggttgatcc gtgcttgctg cttggtgcca
    32581 cgtgcctgta cgccagccct catccaagct aattcctgtt tataaagccg cttgcgcttt
    32641 tctttttgtt ctacttctac acgatcacgt tctgcttttt ctaagacgta agcttcataa
    32701 tttcctttat actcgtataa ttttccaaat gaaagttcga agattcggtt tgctactcta
    32761 tctagaaaat aacgatcgtg ggtaaccatc aatagtgcgc cacggtattg tttcaaatag
    32821 ttttccaacc actcgatcgc ttcataatct aaatggtttg ttggttcgtc tagtaatagt
    32881 aaatcgggtt catcaatcaa cacttgcgcc agactaactc gttttttctg accacctgat
    32941 aaagtactga tttttttatc taattcactg attcctaatt tttgcaaaat aatctttgcg
    33001 ttggtatctg tagtccaagc atcttcttta ttcatttgtt cttctgcttt agcataacgt
    33061 ttttgcacat cagggtcttc tccgttttcc cctagttcga tcaatgcttc ctcatatgct
    33121 cgaacagttt ggatcaaggg gctgtttcct tgaaagactg cttggagaac agttaattca
    33181 tcggaaaatt cagctgcttg agaaagataa ccaatacggt aatcagttgg ataaaacact
    33241 gtttgccgat caccgtcgct gctatcgata ccggcaataa tatttaagag acttgtttta
    33301 cccgtcccgt tcgtcccaat caacccgata cggtcttttt cgtggaccaa aaaagaaatc
    33361 tggtcaaaca aatctttttc accataagtt tttttgaggt cagttacttt taattctttc
    33421 aacatgttcc ctccttatct tggatattgt atcataaaaa tagtgaactt caggaaaatt
    33481 tttttggtat ttgttctttt tgtgttctca aaaaaagaac aggaccgatt cgatcctgtt
    33541 ctgatatgtt ttgtttttta taaaacttga aaatttttac ctttttattt tattggactc
    33601 gttttttttg actttgctcg aaacgcaaat cggaaagaaa agttatcaga tggtttgttc
    33661 atcgtataag attctaacaa attgatattc ctgcgatagc tgttcgcaga aaacgtcgtg
    33721 attttttcag caacttcgta ttcatcaatg atttttcttt caagataata acctcttagc
    33781 atttttttcg taaacagact atcttgctgg atcatccacg aagaaatcaa attccccgag
    33841 ttcattttta ttccttcaag tttgcgttgc tggataaaaa attgaaccat cgtttcatca
    33901 taaatatcag tcaagttatc taaactttca ataatcaact gagtattttt ttgatatgtc
    33961 tctctgattt cttggatatc ttcatcacta ataaatgtct gacgatcagc atatcttctt
    34021 tgccaaaaca ttttcggatg gagaacgatt cgcattaacc tacggacaac aatgaaccaa
    34081 aagccgataa aagacaaaat ctggcttgtg atagaatgtt cgaatcgaga aagaaaacgg
    34141 gagtaaaaac gataaccatt agaagaaagc ttgcccgaac gataactttc atccaatcca
    34201 tcccgttcga tcgacaaaat cagtgcttgt atttcttgta cttcttgctt ttcatcatcg
    34261 gttaaatctt ccaagtacag atcacgtatc cgttcttgat aattttctat cactgcttca
    34321 gtggctaaaa attcttttgt attacgatca atttccttta tttcttttcg caaaacttca
    34381 acgacctctt ctaaaatcat caaagcattc aaatccgtgc ttttcgcttc ctctgtttcc
    34441 gtcagcatag gcaagacaat gatccctatg accaaagtca ctaagatgac acccgccgtc
    34501 agaaacaaaa gcaaagaccg ctggtaaaac atcatattat tgattgaaaa tggcaaaata
    34561 aaaatcgtag ccaaactgac tgttcccttt acaccgccaa atgttaagat caagatctcg
    34621 ttcaactgtt ttttgaactt tttactgcca tctttgaata cataaaaaag actgatagaa
    34681 atgaatctga tcacaaaaag catgacagag attaatacga taatcgctaa taaaagaccg
    34741 tttggatata aaccgtctcc ccatactggc gagaacactt gcgtcaattc gattcctaaa
    34801 aatataaata ctaatgcatt cagtgtaaaa gcaatagttg tccatgtact gtgggacaag
    34861 ctcgacaatt ctgcatcaaa cacagagatt ttcctaaaac cagaagcttg gagaatacct
    34921 gctgccactg cagcaatgat tccagataca tcaaatgcct ctgccaatac ataggctaga
    34981 aaaggaagca aaagttcgat cagcagatac cctgtgacat cttgtgctga tgctttttcg
    35041 atcaaatgaa ttattttttg tttgaaccag acaagcaaaa agccgatcaa agctccccca
    35101 atactagaaa ctactagact catccccgcg tttactgctg aaaaagatcc ggtgatcagc
    35161 gcaccaagag caaactggaa ggcagtaaca ccagatgcat cattcaaaag accttctcct
    35221 tccaaaatat gcatcgcctt tttagggata ttcactcgtc cagaaagaga actgactgct
    35281 accgcatctg tcggacctaa cgctgctcca aaagcaaagc aggcagcaag tgggacactt
    35341 ggcaacagga atgataacgt cgcacctacc ccgacaaggg tcaaaatgac tcctccaaat
    35401 gccaagaaca aaattgtccc gaaatttttg agaatcgaag aaatatctgc tttttctcct
    35461 tctctaaata acaatggtgc aataatcata actaagaaca attcaggttc aaaatcgatt
    35521 gattgtcccc actctgtcag acctaatacc actccaagga aaatttggat cagtggagct
    35581 ggaatcattg gcaaaatgcg gctagctatg ttcgataagg tgatcgttac tgcaaataca
    35641 ataactaact cagcaaattc catcgtccat cccctttatt ttttattttg tgtaagcatt
    35701 tttaaaaatt gttctttttt ctttaaaatt ttggtttcga ctacttcaac ctgtgtttgg
    35761 ttcccctcta attcacactg tacacgtttt gactccaaac gaagcagatc atgtttcaga
    35821 cgttccaact gacgatacat caatatattt cttttacgca acttacaaag tatttgacgg
    35881 cggtcatcca tcgaaagggc gccatagcga tcatgcaaca gttttttttg ttgttcaaaa
    35941 ctctctctca ttttccagat ctcctataca caaacttcca tcattatagc aaagttcttt
    36001 ttggatgaaa aatatttcat tgtttcatcg tttattgcta gttagaaatt tccataaatt
    36061 tttcaacgcc tcattctatt ccaaatagta tcagatatca agtaaaactt aagaaagata
    36121 aaagtttctg acaaaaggat gtttactttc ccattcctgc ctttcttgtt cttttatcac
    36181 aacaaaaaaa tggggctgcg acaaaaatct tgtcacagtc ccttattctg aataaacggt
    36241 gtggaagaga cagcctatca gtagtaataa gacacatctc tttcacagcc tcatttttgc
    36301 gtaaaaatcg atttattcga aaaattcccc gtatacatct tctacacgtt gatctggatt
    36361 gatcacgata tacaagttac ctgttttttc gctgattttt gttgattgat attgattgtc
    36421 taatccttct gttcctttat ctagatatgg gaagtacaca agatcaggtg tgccatttcg
    36481 gtaaaggatt tccattcgct cgatatcttc gtatttcaat gcgcgattaa acatgcccat
    36541 ttccagtccg cctaggttga tatcatgtgt cgcaactgcg tccccttcat ggaagatttc
    36601 gattttaaat ccagcacacg gatggatttc aacaaattca ctgccattga ttcgtccaaa
    36661 acttgttgtg atttgtttga tccaaagatc gccgatatga cggcggttga tcgtccaggt
    36721 ttctccattt ctaaaataaa attttagcgc tgtcatttct ttactcatta aaaagactcc
    36781 tttatgatgt aatttattct tgtactacct cagtttagca caaatttatg taagtggtca
    36841 catcttatgt tttttcttct aatgacgtat ctgcccactt taagtagcca acaaagctga
    36901 gcagatacag tctagtgttt tttaaatcaa tttttctttc gataaaaaat ccaaaacctg
    36961 ttttttatca ttttttattc tttgttctac gacggctttt tcagctaatt gcaaagcttc
    37021 actaacccac ttaccaggtt tttttccagt ttcttctagc aagattttac catctactgc
    37081 taattcgctt aatgacttga taggtaaacg atcataggat tctcctacgg catccatctg
    37141 aggtgtttcg tcaaaataga tcatcaattc ttctacttgc agtgcatgtt ttttgcctaa
    37201 gaagtacaat tcgaatggtt ccaaagctcc agtttctcgt tgtcgtagtc cttggacaag
    37261 tgcttgaacg tctttaatca tttggttaga acacttccac gatttcaaaa aggaacgaat
    37321 ctcattttct tttagatcca gttggctgat caataatgcc catgcttggc tctcttcttt
    37381 caatgggacg gatggtaatt cagcaaaacg taaaagtgct tcgccttctt ctttcaaacc
    37441 gggacagcaa atgtagcact ctgtttcaat aaatgcatgg attcccgcgg cccgttcatt
    37501 tcccaagagc atcttgatga attccacatt tatacgttct acagatattt tacctaatag
    37561 ctcgtggttt tctttgatgg cgtagaaggt ttcttcctct aatttgaacc ctagttgact
    37621 gacaaaacgc aacccgcgca tcattcgtaa ggcatcttca tggaaccgct catgaggatt
    37681 gcctacagct cgcaagatct gttcttctag atcttgcaga ccatcgaaca aatcgatgat
    37741 ttctccatct tctttcaaag caaacgcatt gatcgtaaaa tctcttcttt tcaaatcttc
    37801 tgccaacgaa cgaacgaatt cgacatgatc tggtctacgg tagtcctgat aagttgattc
    37861 cgtccgaaat gtggtgatct catattgttc atcattttct aataccaaca cagttccatg
    37921 ttcgatccca atatctatcg tttttggaaa aagctgtttg atttcttctg gaaatgcgct
    37981 tgttgcgata tccacatcat ggattggctg gttcagcaag atatcacgaa cacttccacc
    38041 tacaaaataa gcttcatatc ctgcattctc taattttttc agaactggaa ttgccttttg
    38101 gtattccaga ggtaattgtt ttaatttcat ttttccaacc tttcctgcgt gtttcttgtc
    38161 ctgagataaa gactcagttg catggtgact gtttgacaag tccgtttcag agtcttcaag
    38221 gccaggacca cttcatcttg tttactcgtc cttacgctca aagcgattat ggtctctttg
    38281 attgaatttt tccatgtttt tttcaaaaac ttcagttaag tcgatattca atgaattagc
    38341 catgatcatc gtaacgaata aaacatcacc aagttcttct gctaccgagt taactggttc
    38401 agaagccttt ttgctttttt ctccataagt gtggttgact tctcttgcca attcacctac
    38461 ttcttcagtt aatcgagcca tctgagctaa tggagagaaa taccccacct tgaattgctg
    38521 gatatattca tccacttcct gctgcatact gtataaagaa cgctttttat ccatcttttt
    38581 ccctccaaaa ctatcttacc aaaactttaa cgcaaatcct agataagagc aattgagaaa
    38641 atcgaatttc catgctacat ttaggaagga atttctaaat ggaaattctg tgaaaataca
    38701 taattgaaag ctggaattca tatggtcaaa cgaaaaacag taaaagaagt tctttttatc
    38761 attataggaa caagtattta tgcatttggt cttgtttact tgaacatcgc taatcattta
    38821 gcagaagggg gagtctcagg gatcaccttg atcttaagag ctttatttgg tattgatcca
    38881 gcttatacga ctttattaat caacatccca ttgattttac taggaggaaa gatcctcggt
    38941 aaacgttcct tggcctatac tgttctaggt acactttctt tgtcattctt tttatggatc
    39001 tggcaaaggg ttccactaga aatcaattta cagcatgatc tactgatcgt ttctctactt
    39061 gcgggtttag ttgcaggtgt aggaagcggg atcgtctacc gcatgggtgg aacaacaggc
    39121 ggcagtgata ttatcgctcg gattttagaa caaaattacg gcatcactat ggggcgttcc
    39181 ctattggcat ttgatatcat cgtcttactt gcttcattaa cctatatcga cttgaaacgt
    39241 atgatgtata cgttgattgt ttcgtatgtt ttcagtcgtg tgattgattc gatcttagat
    39301 ggcggatatt ctgcaaaagg tctacttgtc gtctccaaca aaagcgaaga gattgcacca
    39361 ctactgatga ccggtctgca aagaggtgtg actttccttt ctggagaagg cgcattctct
    39421 ggtaattcaa aaaaaatcat ctatatggtc gttagctcta gtgaattaac tgaagctaag
    39481 aggatcgtcc acgagattga cgaaaaagct ttcctttcaa tcatcaatgt gcatgaagtg
    39541 gaagggcaag gctttactta tttgaagcca cagacaagat tactgaaaaa actataagaa
    39601 aaaagacaaa gataggctat gaggaaagat tccacatcca gctgaccttt gtctttttta
    39661 gtactatact atttttaact aattgttatg ttcacttacc cggttacttt tcttttgtgt
    39721 ctgcaaaagg atctttcggt taacttcatc agataatttc aaaaaagcat ccctatctcc
    39781 atcttctagt gcttgatcga tttgagcata aagcattttt agttttgcct cttcttcttt
    39841 ttcttgaaaa tatcgttcaa ttaattcagt atcttcttca ctgactgaag aatcccaaga
    39901 agaaaatgga ttgtcttcta agatagatag atattctctt gtctgccaag cattttcgaa
    39961 tatacattcc acatataaag gctttttcca attcaaacgg atttcatgaa aaatctggtc
    40021 tgtgtccgta aattcttttc cctgcaaaaa caatttcatg ggttcccctt caacagatag
    40081 atcactgatc tgcagtcctc gatccgcaaa attcgcccct tcaacaaagt ggacattgct
    40141 taaaatcgct tcatgattgg caagataatt caagatccaa aaaacttctc ttcggctaaa
    40201 agatacatga ttgaccatcc acgttaaaaa attcttcttt tcccgtacat caattagcat
    40261 ttttctcacc tctctgttag gtcatctaat aatgacagtg cctccatatc tcctggttca
    40321 agtgttaaat aataagtcaa taattcttgc gctcttttca gctgcccttc ttctcttaag
    40381 aaaaaggcat actctttcaa gaaatctggt tcatgtgata gttcatgata agcctgttca
    40441 tagtgtacag ctgcaacggt aaagtcttct aattcattat aagcatgggc taggttccat
    40501 tctgcataag gattagcagt ttcttccatc tgattgatca cttgtatcac atcttcatat
    40561 ctttcatcat ccaagtaaag attacttaaa gtaagtaatg tttcatcttg tttgtctcct
    40621 acttctaaag ctttcagtaa aagttcttct gctcgctgtc tatcatgcag acggaaagca
    40681 ttttccgagg ccaggtgata aagttcgact tggtaaggat tttctttgat tccttcttct
    40741 aacactgttt gtgcttcttc aatcatttct tcttcttgaa gagcttgtcc tagatataga
    40801 tataacgatt gataatgcgg attaacttct cgaagttctt ccagatagtt gattgcctgc
    40861 tgattttctt tcaattgaag attcgtaaaa gctagctgga acagtcgatc atctgtcctt
    40921 tcttctttca gtgcttcttc taaaggtacg atagctgctt cgaattctcc ttgcatactt
    40981 aaggattgtc ctaaacgttc ctgcatcgag attcctgaaa tttcatttat cccgcttgcc
    41041 aacaatgttt cataaaccac tgctgcctct ttgaaacgat caactgaaaa atacaattca
    41101 gctagcgcaa actggatcaa tggttcatca ggaagcaacc cagctgcttc tttcaatttt
    41161 gcttcactca cttcagggat tccgataact tggtacaaat cagctatcgc caataagctt
    41221 tgcggatagt aatcactttg cttatccact ttttccaggt attcaaaagc taagtcgatc
    41281 tcattatctt cgattgcaat ttctgctaac gggatgttca gtccgtcatt ttctgggtat
    41341 tggttgatca gttgttcaaa aatctgtttt gcttcgatca aaaagccaat agccagcaat
    41401 tcttcgccta gttcagctaa tatatctgct gggtcttctt ttaatgcttt ttctaaaaag
    41461 atttgtgctt gtgacaagtc ttcatctgat aaagcttgca acattttttc gctatttgta
    41521 ttcatttcaa ttccctctta tctcactgac gatttgttga aataccgtca ttgttctcaa
    41581 taattctttt tcgtttggat gttggtatcc gtctattata cctatttttt ctaaaacaag
    41641 tatttttttg cttttttctg ccaaaaaaag aactttttcc aaatactcca tctttgaaat
    41701 ctgttccagc cagtggattg gatagccaag caagtccagc cacacaaaaa agttttttag
    41761 ttggaaatca aaaggatatg cttggagatt ccacacgaaa tgaaacatca ttcctaaaaa
    41821 ttttttcata ctagcagaaa gtagatggcc attttcggtc agataaaaag cttgttcaaa
    41881 cagtttacca taatttgaca ggttttctgc ctctaattga taaaaataga tcatttcttc
    41941 gatcatcccg gcaaacggcc gagtcgttaa ttgcttttta tttggatagt ttttatacag
    42001 attttgcaaa aaacgatgat cacaaatcat tccgcaacag ataaaagtca aaaagtcaat
    42061 ctgctttccg tccacctgcc gctcgctgat tgtttgatca taaacgatgc gttctggcag
    42121 attgatggtt tgcagcacta cacgatttgg tagctgcaaa atcgtccgct gcggtgttaa
    42181 tgctcggctt agagaacgga tcgatacagg gatcatccat agtgatgaat caagggttgt
    42241 atgtttttga aaaaaacctg ccagatccat gatcccttca tttccaaatc cgatgataaa
    42301 catggattga ttttcgggat agcgtttgac gaaatcaagc aggttcttta attctgttaa
    42361 atgattgcat tgagtgttgg cacaaatata ccagtcattg tttgcttgat ttgcaaataa
    42421 cgggttgatc ttatctgcaa acaaatcata atagcgctga ttcgttaaaa ataagattgg
    42481 ctgatcaatg gaaagttctc ttagctgact gactagcgtt tctccgtaaa acactttcgt
    42541 caacgcatct tctacttgat aatcaagttc catacgcatc cctcctcttc ttatttttat
    42601 tttaccatta gtaagcaaat tctagaaaag ataagagcaa agctcacctc ataacttgca
    42661 aataaataaa aattaaataa aatacatgtg ttttctatgt atgacatacg gattcggaat
    42721 ctctgtctct tatttattcc ttttctgcta ggaaataaaa agaaaagcac ttgtagccct
    42781 agagccacaa gcgctttttc aactgtctta tttaacagcg tcttttaatg ctttacctgg
    42841 tttgaatgca ggtactttgc tagctggaat ttcgatttct tcaccagttt gtgggttacg
    42901 acctttgcga gctgcgcgtt cgcgaacttc aaagttacca aaaccgatta attgaacttt
    42961 ttcgccgtta gctaaagcat cttgaatagt tgaaaataca gcatctactg ctgcagttgc
    43021 atctttttta gttaaatcag tagctgaagc aactttttcg attaattctg ctttgtttgc
    43081 catggataga ttcacctcct ccacaagaga tatgatagaa atatcattta gttaaaactt
    43141 tctgagtggt ccagaagttt aaaaagaaat attgattaac ttcaatattc tgttatcacg
    43201 atatcatatg aaccgcttaa tagcaaggtt tttaccaatt ttcacatgct ttttttagtc
    43261 atagaaacgt aacaaacgaa actgtctttt tcttttgaaa aaaaaacgtc gatatggtaa
    43321 aatgcctatt ttctcctacg agggataatt cggatggacg tcccttcaaa agtaaatgct
    43381 tttctgattt gattttctaa gaaacgttca taagaaaaat gcatcaattc ctcttcattg
    43441 acaaaaacga caaatgtagg tggtttgaca gcgacttgtg tagcataaaa aatcttcagg
    43501 cgttttcctt tatctgttgg tgttggattg attgctacag catccataat gatatcattc
    43561 aacacagccg aagagatacg aagattctgg ttcatactta cttgttcgat catttcaggc
    43621 agacgttcca accgttgttt agtcactgca gaaacaaaaa cgattggagc gtaatcaaga
    43681 taccggaatt catcacgaat ctcttgttcg aaatcacgca ttgtattggt ttctttcttt
    43741 acaagatccc atttattcac gacgataata attccacgac cagcttcatg ggcgtaaccc
    43801 gctactcgct tgtcttgttc ccgaatccct tcttcagcat tcagtaccat caaaacgata
    43861 tcagaacggt caatggcacg cattgcacgc atcacgctgt atttttcagt attttcgtat
    43921 acttttccgc gtttacgcat accagctgta tctatcatta agaatttctg accactttca
    43981 gaaacgaagt gggtgtcgat tgcgtctcgg gtcgttcctt caatatccga aacaattaca
    44041 cgttcttctc ctaaaatcgc attgatcaaa gaggatttac caacatttgg gcgaccaatc
    44101 aaactaaact taatcgtgtc gtcgtcctct tcttcagtct cttcagagaa atacttcact
    44161 gcttcatcta aaatatcacc aatccctagt ccatggcttc ctgaaacagg ataaggatcg
    44221 cctagcccta aggaataaaa ttcatagata tcgtttctca tttctggatt atctacttta
    44281 ttgactgcta aaatcactgg tttattactt ctgtataaaa ttttcgcaac catctcatct
    44341 gcgtctgtca cgccttcgcg tccgctgact acacaaatga ttacatctgc ttcttcaatc
    44401 gcgatttctg cttgatgctt gatctgatcc ataaaaggtt catcgccaag atcaattccg
    44461 cctgtgtcga tcacgctgaa ttctcgacct aaccattcac cttttgcata aatacgatca
    44521 cgagttactc caggagtatc ttcgacaatc gagatacgct caccagcgat gcggttaaaa
    44581 atcgtagact taccgacgtt cgggcggcca acgattgcaa ttgttggatt tgccatatta
    44641 tttcctcctc acaagtttcc aatctcactt agtttaacga atgcattgcc aactttcaag
    44701 catagattgt caattaaacg aagtattttt attccttatt gaaatactaa tcgcttttca
    44761 aaagaa
//
LOCUS       DAIGSZ010000019        40276 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.019, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000019 DAIGSZ010000000
VERSION     DAIGSZ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.019"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            2..74
                     /locus_tag="NOB31_001059"
     tRNA            2..74
                     /locus_tag="NOB31_001059"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="NOB31_001060"
     tRNA            78..150
                     /locus_tag="NOB31_001060"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="NOB31_001061"
     tRNA            155..225
                     /locus_tag="NOB31_001061"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="NOB31_001062"
     tRNA            238..311
                     /locus_tag="NOB31_001062"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="NOB31_001063"
     tRNA            323..394
                     /locus_tag="NOB31_001063"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /locus_tag="NOB31_001064"
     CDS             660..1853
                     /locus_tag="NOB31_001064"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HCI0973284.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="NOB31_001065"
     CDS             1983..3455
                     /locus_tag="NOB31_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0973285.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="NOB31_001066"
     CDS             3538..4326
                     /locus_tag="NOB31_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HCI0973286.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMASTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="NOB31_001067"
     CDS             complement(4393..5061)
                     /locus_tag="NOB31_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HCI0973287.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="NOB31_001068"
     CDS             5176..6888
                     /locus_tag="NOB31_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0973288.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="NOB31_001069"
     CDS             6891..8663
                     /locus_tag="NOB31_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0973289.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(8745..9866)
                     /locus_tag="NOB31_001070"
     CDS             complement(8745..9866)
                     /locus_tag="NOB31_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0973290.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(9938..11218)
                     /locus_tag="NOB31_001071"
     CDS             complement(9938..11218)
                     /locus_tag="NOB31_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HCI0973291.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLSDLNKQITMLKNDIILLKKEKEDLNDEINQKYDETLKNVYSSLIVSN
                     IEETSSSEIKNKLSLLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            complement(11309..11761)
                     /locus_tag="NOB31_001072"
     CDS             complement(11309..11761)
                     /locus_tag="NOB31_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCI0973292.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(11774..12184)
                     /locus_tag="NOB31_001073"
     CDS             complement(11774..12184)
                     /locus_tag="NOB31_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0973293.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            12459..12671
                     /locus_tag="NOB31_001074"
     CDS             12459..12671
                     /locus_tag="NOB31_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0973294.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            12674..12886
                     /locus_tag="NOB31_001075"
     CDS             12674..12886
                     /locus_tag="NOB31_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973295.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            13026..13181
                     /locus_tag="NOB31_001076"
     CDS             13026..13181
                     /locus_tag="NOB31_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973296.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(13178..13402)
                     /locus_tag="NOB31_001077"
     CDS             complement(13178..13402)
                     /locus_tag="NOB31_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HCI0973297.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            13480..13668
                     /locus_tag="NOB31_001078"
     CDS             13480..13668
                     /locus_tag="NOB31_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973298.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            13665..13838
                     /locus_tag="NOB31_001079"
     CDS             13665..13838
                     /locus_tag="NOB31_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973299.1"
                     /translation="MKKTDTLFIGFILGLLVIVAHQSIIGGSLFAALMVLINLLDSKE
                     RSNYGTRRSAKNR"
     gene            13994..14329
                     /locus_tag="NOB31_001080"
     CDS             13994..14329
                     /locus_tag="NOB31_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973300.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            14562..15503
                     /locus_tag="NOB31_001081"
     CDS             14562..15503
                     /locus_tag="NOB31_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HCI0973301.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            15505..16395
                     /locus_tag="NOB31_001082"
     CDS             15505..16395
                     /locus_tag="NOB31_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HCI0973302.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            16438..17238
                     /locus_tag="NOB31_001083"
     CDS             16438..17238
                     /locus_tag="NOB31_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCI0973303.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            17253..18104
                     /locus_tag="NOB31_001084"
     CDS             17253..18104
                     /locus_tag="NOB31_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0973304.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            18305..18766
                     /locus_tag="NOB31_001085"
     CDS             18305..18766
                     /locus_tag="NOB31_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0973305.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            18792..19244
                     /locus_tag="NOB31_001086"
     CDS             18792..19244
                     /locus_tag="NOB31_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973306.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            19350..19544
                     /locus_tag="NOB31_001087"
     CDS             19350..19544
                     /locus_tag="NOB31_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973307.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            19575..19868
                     /locus_tag="NOB31_001088"
     CDS             19575..19868
                     /locus_tag="NOB31_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973308.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            19898..20338
                     /locus_tag="NOB31_001089"
     CDS             19898..20338
                     /locus_tag="NOB31_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0973309.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            20413..20880
                     /locus_tag="NOB31_001090"
     CDS             20413..20880
                     /locus_tag="NOB31_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HCI0973310.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            21627..21857
                     /locus_tag="NOB31_001091"
     CDS             21627..21857
                     /locus_tag="NOB31_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973311.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            22016..22849
                     /locus_tag="NOB31_001092"
     CDS             22016..22849
                     /locus_tag="NOB31_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HCI0973312.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            22842..24257
                     /locus_tag="NOB31_001093"
     CDS             22842..24257
                     /locus_tag="NOB31_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCI0973313.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            24269..25798
                     /locus_tag="NOB31_001094"
     CDS             24269..25798
                     /locus_tag="NOB31_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI0973314.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            25716..26768
                     /locus_tag="NOB31_001095"
     CDS             25716..26768
                     /locus_tag="NOB31_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HCI0973315.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            26770..27087
                     /locus_tag="NOB31_001096"
     CDS             26770..27087
                     /locus_tag="NOB31_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973316.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            27214..27837
                     /locus_tag="NOB31_001097"
     CDS             27214..27837
                     /locus_tag="NOB31_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HCI0973317.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            27852..28742
                     /locus_tag="NOB31_001098"
     CDS             27852..28742
                     /locus_tag="NOB31_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HCI0973318.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            28765..28980
                     /locus_tag="NOB31_001099"
     CDS             28765..28980
                     /locus_tag="NOB31_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973319.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            28992..29333
                     /locus_tag="NOB31_001100"
     CDS             28992..29333
                     /locus_tag="NOB31_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973320.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            29333..29704
                     /locus_tag="NOB31_001101"
     CDS             29333..29704
                     /locus_tag="NOB31_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973321.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            29697..30092
                     /locus_tag="NOB31_001102"
     CDS             29697..30092
                     /locus_tag="NOB31_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HCI0973322.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            30094..30471
                     /locus_tag="NOB31_001103"
     CDS             30094..30471
                     /locus_tag="NOB31_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973323.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            30472..31080
                     /locus_tag="NOB31_001104"
     CDS             30472..31080
                     /locus_tag="NOB31_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI0973324.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            31080..31421
                     /locus_tag="NOB31_001105"
     CDS             31080..31421
                     /locus_tag="NOB31_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973325.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            31663..34452
                     /locus_tag="NOB31_001106"
                     /pseudo
     CDS             31663..34452
                     /locus_tag="NOB31_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
     gene            34442..35182
                     /locus_tag="NOB31_001107"
     CDS             34442..35182
                     /locus_tag="NOB31_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI0973326.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            35179..37941
                     /locus_tag="NOB31_001108"
     CDS             35179..37941
                     /locus_tag="NOB31_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI0973327.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYE
                     RPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYS
                     GYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIIN
                     WARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISS
                     IVIPPK"
     gene            37954..38862
                     /locus_tag="NOB31_001109"
     CDS             37954..38862
                     /locus_tag="NOB31_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HCI0973328.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            38862..39482
                     /locus_tag="NOB31_001110"
     CDS             38862..39482
                     /locus_tag="NOB31_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973329.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            39486..39935
                     /locus_tag="NOB31_001111"
     CDS             39486..39935
                     /locus_tag="NOB31_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973330.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKAKLDGLANITFEKVGTV"
     gene            39935..>40276
                     /locus_tag="NOB31_001112"
     CDS             39935..>40276
                     /locus_tag="NOB31_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973331.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYR"
BASE COUNT        13793 a         6035 c         8261 g        12187 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatggc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattttttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtatctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaacggt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcatgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc agaaaagggg caatttaaat ttctattttt
     8761 cctagttttt ctactagttg attttgcata tttttagttg tatgagtata aatctttaat
     8821 gttgtttttg aatcttcatg tcctacacga tccataatgg cttttaatgg gattcctaat
     8881 tctgtaagta gagaaatgtg ggaatgcctt aacatgtgag aagaaacttt tttatctagg
     8941 tttaattctt tggatactgc tcttaaagat tgattatatg cttgaataga tatcgggtta
     9001 ccatttttag agatgaaaat gtatttatct ttattattct taattaattt gttttcttca
     9061 attaattgat ctatgatttc tttagcatta cttgataatt caatggttct ataagaacct
     9121 gtatttttag ttgttgtttt aatttttaac tcgtaatcat aagtaccaga aaccgtaatt
     9181 ttattaccat cataatcaga ttcagtcaaa gatatcaatt caccataacg tagtccagtt
     9241 aaaaacaaaa atttagtaat taaagaataa cgtgactgtt gatgtgaact tttttgttta
     9301 ctagcaatca tttgaacttc ttcttttgat aaataaccat ctttttcttt ttttatttct
     9361 tcgtttgtct taggttttct tgctaaagaa accccattta cgggattata ttttaatcca
     9421 tatcgacggt tggcgaattt aaaaatcatt cctgtaaaag tttttaaatg tattacataa
     9481 ttatatgata aatttttttc aaaatagtag taatctagca tatcttgtat aagattacta
     9541 ttaacgtttt ttacaagtac atcatctttt atatattttg aaattaatga tagataaacc
     9601 tgagttgttc gataggaact ttcttttaca gttggcttgt atttttcatc ccatttagtt
     9661 tttaattctc caaaagttag tggtaattct tcatttcgtt ttattttttc tgcgattttt
     9721 tcattcaaaa gtaagttagc ttgattccaa gcttggcgtg aattgctaga taaagtaacg
     9781 gacacttttc tctttttttc agttaaggga tccgtataac gttcggtgta cttaaatttt
     9841 ttgtcattta ttttttctaa ccacattatt tctattcctt tcgaatatac gttcctatta
     9901 attgttaaaa gaaaaagccc gaaggctttt tatatattta atcttttgac aattctaaag
     9961 atcgtctata ttgttcagct ttagctaatt ttgtaaatgt tactgttcca ttataatttt
    10021 ctaaaacaac tttctctatt tcgtctagtg aaactttgaa aaattctttt ctttgattaa
    10081 ttttattaac ttcttgtttt ctaaaatgat tatgcaattt agtttccaaa gacggagcgt
    10141 cctctgaaaa aatcatcgca tgaacgtcaa attcaaatgg aaccgatgca ctactcaatt
    10201 cttttattct atccataggt tctaatcttc tagtcatacc aattttatat atgtcttcac
    10261 caaaagaccc aatattacta attacataca cataaccggc tctagtattt aattctcttt
    10321 gtaatacatt ttcacgtata acttctaatt cttttaattt ttcttccagt tcttgaattt
    10381 tatttgcata taattctttt tccacatctg cattagcttt ttgcatatat gcgattaatt
    10441 tggaaatttc agaattgaat tgacgttgtt ctttatcaat acgtttcttt tcacgatcaa
    10501 tttctctacg aactttttcc tcttctatca tctgttcttt tattgctttt tgttgttctt
    10561 tttcttcggt aattttcact aaataagagt aatgaagttc tagttcttga agtttaaact
    10621 ctaaaagacc cttccttaat tcagcattgt cattcttgaa taaattatta attttatcaa
    10681 atatttttat gattttttcc ctagtcgagt ctatattaga aatagttagt ttattgagta
    10741 atcctttcac ttctgaatca aatggaatga gcattttttt ctttaaatta tttttctctc
    10801 gtttatttaa aataagaggg acagaaacag catcgtcaat aatatattcc ttttctttta
    10861 attttaacaa agaaagctta ttttttattt cagaagatga agtttcttct atatttgaaa
    10921 cgataagtga agaatagaca ttttttaatg tttcatcata cttttgattt atttcatcat
    10981 ttaaatcttc tttctctttt tttaataaaa taatatcatt ttttaacata gtaatttgtt
    11041 tatttaaatc tgatagtgtt tcttccttac ttaatataaa tctttctcta tcatgtaatt
    11101 tatttagttt ttcatcattt ttttgttcta attcataagc ttcttttttt attgtgttag
    11161 ctttcgacag tttagtgatt cctataatta ataaaataag tccaatcaat aataacattc
    11221 aaaactcctc atttctttga tataattatt gtagagttta ctcagaaatg aggaaagagt
    11281 ccatgtgaaa gcatgggctt ttttattttt aatgttgtaa tactaaatgt tcaagattat
    11341 gaggaagccc taaatattca ataatttgga actgactcat atcagataaa tcttgttcat
    11401 ctattgttct agttaacatt tcaattgcaa acatattagc ttcagcttct ataccataaa
    11461 tcatacaact aaggttgttt gctctaaaag ctgctgtgca aataccttta tggagtctaa
    11521 cgtgggctat ttcatgccat aatacaaatc ttttcataga aggtgatagg ttttgattaa
    11581 ttaatatcac ataacatctt ttattgtgta tcgtttgtcc taatgtttta ttccctaaat
    11641 cagtttcaat taaatctata tcagaatatt tgattatttt atatggatta atcgcatcag
    11701 atccaaactc tacaaataat ttttctattt cttctaatat ccagtatttg tttaaatgca
    11761 taccaaagcc cacctattga cgatattttt taggagtgaa ttttttcttt gctttaactt
    11821 tggttaaggc aagtgcaagt tgaatggcat cgtataattt ttccttatct tcatcgtcta
    11881 aaggttcacc ataataattt gtttcagcat ctgaattcaa gccttcaagt aatttttcag
    11941 cttgtaaagc aatatcttgt ttatcttttt ctgttaaatc ataataatgg cgtttatcag
    12001 tacgtcctaa aagataatca gttgatacat taaagtaatc tgcaactttt tgtattttat
    12061 ctccagatgg agtactttta ttccatctag acatgcttcc atttccgaaa tttaactttc
    12121 tttcaagttc tgccaacgtc attgaacgtt cttttaataa gatttttata cggtctaata
    12181 gcataggata tgcattcctt tcaaaatacc gacaaaaaaa gtatttttct gcaaattatc
    12241 tatttacaaa tagagaattt gcagttatac tagttttgta agcaagatat ttacggcata
    12301 caaagactaa aagcaataaa ctaatagtct ccccagacat cagtaagctc gctttttgtg
    12361 cgctgtattt tgtatgctta cataatagca tatttgcagt ttttgtcaaa cttattagac
    12421 aaaaatatta gaaaatattc gataaggggg tatgaagcat gactttaaaa cagcaagtat
    12481 taattgcttt agtaaagaaa ggttggagtc aaagagagtt agctcgacga atgggtatat
    12541 caattactta tttacgagat atcttcatcg aaaaaagaaa acctaaggaa cgtttaaaac
    12601 aaatcgaaga acttttggat atcaagttag aagtagattc taatgatcag ccatcagaac
    12661 aggaggcgta aaaatggtac aacgtttgag caaagcggag tttaaagaga aatataagta
    12721 ttctgaaagt acttatcaaa gaagaatgaa ggaatttaaa aaatcacgtt ttagtgaggg
    12781 gtataacgca gttacttcca aagaaataac aattgatgtc gatttatatg aacagtttag
    12841 aacatggcgt tctaaaaatc gatttagagt tagagctgtt tgttaatagc taaaaaatct
    12901 aaattcacca cttctgaaaa gaggagttgc tgctctcctt tcaagtttgc caaagtccac
    12961 gttttttcat tttggcaact cctcttcttg gaggtggtga cggcgagaga cgaaggaggg
    13021 atgacatgaa ggaagaatca aaaataggga ttttgaatga gaacaattac acaagattaa
    13081 ttattgaaac agaagaaggg aaaaaagtag cagaagttac attgaccgat gcaactcctg
    13141 ctgacggtta tcgtattcga ttaactccta aatatgatta accttttggt gggtgtggat
    13201 cgtttccgtg actatcacgg ctttgaattt ttccatctct gccatgaata aatagctcag
    13261 atccttgatt tttagaaatc tctctagcga tttttactgc ttctgatttt gtattagtat
    13321 gtgcagtcgc tttagaattt ccagcacctt tgacattcca accaccattg gaattaggta
    13381 caacatgttg attttttccc atagttttca cctccatttc tatagaaata ttttatcaaa
    13441 tagaaatgga gaaattcaat aaacgaaagg agaagtgata tggcatatac cttgcaacaa
    13501 gaacatcaaa ttctcggttt gattaaacaa cgcaggaaac aattacaaga tgaccgtgca
    13561 gcgcttagaa aagccgatga gctatcagat aggcaagctg aactaattgc ttctgaactt
    13621 gaggatttga gaatgctaga aataaaaaat agggagatta gattatgaag aagacagaca
    13681 cactttttat aggattcatt ttggggttat tagtgattgt agcgcaccaa agtattatcg
    13741 ggggaagctt gttcgcagca ttgatggttt taatcaatct gcttgattca aaagaaagga
    13801 gcaactatgg cacgagaaga agcgctaaaa atcggtaaag tgattgctga taatcggtgg
    13861 ggaaatagcc gccctattat tttaagcaag caacatatcg aaaagcaaaa agcatggcaa
    13921 caaataaaaa agtgactctg ccagccagca aagagtcaca tacaaattta taaaactagg
    13981 agaattatat cacatgaata agaaaattga aaatcttatc gaagaattga aacgtgaatg
    14041 ccaaaagcaa ggtgtttcta ttatttgtac agcccaaaaa gaaggggaac ttaaaagtct
    14101 cgtttatggt gagacaacag aaattttact ttgtcttgct atgcaagaag aacatttaga
    14161 tgaaaatctc ccattgtcag cacatattat gcgtagaatt gctgtggatg cttacgaaca
    14221 agcgaaaaat gaagaagaaa atcaaccttc aaatcatact tttgttatta ataacaagga
    14281 agatttagct gatgtgatga ctcgtattct caagggggaa tttcaatgat gaatgaaaaa
    14341 acaattgatc tactcattat tttatttttc acgttagtga ttgtagcgaa aagttatgta
    14401 atctttggct tgttattcgc aattaccatg cttgtgcttt gcgtgttagc aagcagaaaa
    14461 gaggttaaac atgaacgagt tagcaaatct tgacaactat ttaactgatc ctgattatgc
    14521 taaaccacca tatgaagcac caattgatga ggaggatgaa gatgagtaaa tctaccttag
    14581 aaatgagcca tcaagaatgg cttgaagacc gtaagaaagg catcggaggt tcggatgttg
    14641 gaacaatttt aggattgaat aaatggaaat ctccttatca actatggcta gaaaaaacag
    14701 gacaagtagt acttgaagaa tcaggaagtg agcccgctta ttggggtaat gttttagaag
    14761 aagtggttgc taaagagttt caggaacgta caggcaaaaa agtacgcaga agaaaccaag
    14821 tatttgaaca tccattacat ccatttttaa gagcaaatat tgatcgggaa gtagtgggag
    14881 aaaatgccat tctggaatgc aaaacagcca atcaatttct cggtaaagaa tgggaaggcg
    14941 aagaggtacc gcttagctat ctctgtcaag ttcaacatta catgaacgtt ctaaacaaag
    15001 actattgtta catcgctgtc ttaatcggtg gtcaaaaatt tatctggaag cggattgaac
    15061 gagatcaaga gctgatcgat acaatcactg aacaattagt agagttttgg gaaacaaacg
    15121 ttcttggagg tatcgagcca attattgatg gtagtcaagc gacagctgat ttcttgaaag
    15181 agaagtatgc agatgttgaa gacgttcaaa cgacgttacc aattcatttc gatgaactag
    15241 ttgaacagaa aaacgaactc aaacggacta agaaagaaat tgaatcagct atccgtcaag
    15301 tagacaacga gattatcagc gagctaggta aacgtgaagc cagtatcggt atcactcaaa
    15361 aaaacatcat cagttggaaa tttgtccgta cgagacgtat gaactcgaag aaactagcag
    15421 agaaatatcc agatgtcgca aatgatgaag agatttataa cgttactgaa tcaagaaggc
    15481 taaccgaaag ggagatcaaa taatatggca acaaatgaat cgttaaaaaa tcaattggca
    15541 gcaaagccac agaaacaagt tgcaccaggt caattaggac ttaaagcttt gatgaataca
    15601 ccaacaatga gaaagaagtt cgaagaggtg cttcatgaca atgctaatgc ttttatgtcg
    15661 aatgttatga ctcttgtatc taatgacagt tatcttgcag atagtgaacc gatgtctatc
    15721 atgagtggtg cgttaactgc tgcaacatta aatcttgggc tagataagaa tttaggttat
    15781 gcatatttag ttccattcaa tagtaaaaac aagcaaacag gaaaatggga aaagaaagct
    15841 caattcatgc ttggctataa aggatatatc caattagccc aacgatcagg taaatacaaa
    15901 gcattaaatg tgatcgaagt ttacgaagga gaactaaaaa gctggaaccg actgacagaa
    15961 gagtttgagt ttgatccaaa tggtagaacg tctgatgaag tcattggata tgttggctat
    16021 ttcgagttac tgaatggatt caaaaaaact gtctattgga ccaaacaaga aatcgaagct
    16081 catcggattg ctaacaataa agatcgcgat aagacaaagt taagtggtgt gtgggcatct
    16141 gattacaatg caatggcacg aaaaactgtt ttgagaaatc ttctttctaa atggggaatc
    16201 ttgtccatcg aaatgcaaga agccaccaca tcggatgaga gagtccaaag ggttcaagaa
    16261 gacggcagca ttattgctga aacagaagtt gaagaagata ttcctgaaag aaaagaagca
    16321 gaggttatat ctgaagaaaa tgaagatgta caaactggat tatttgatgc atctaatccg
    16381 ccgttaaaca aataatgagg gagctttctc ccttgctttt ctagaggaga aatacgaatg
    16441 aacacaggat atgtcaaatt acatcgaaaa gtgatgaatt cattcgtttg gaccaatcct
    16501 tatatgtata aattatggaa cttgtgtttg atgaaagcga gtcatgagaa tcgcaagata
    16561 ctttttaatg gaaaagagat acaagtgaac agcggagaat tcgtcacagg gcgcgatgct
    16621 atcacatctg agatgaacga aggcgtgaaa cgtgaacatc aagtgaacag cggttctgta
    16681 tggagatggc taaaacaatt tgaaaaaaac ggaatgttga acatcaaatc aactacgaaa
    16741 tacagcgtta tatcaataaa aaactggtct ttgtaccaaa gcagtgaaca acaaatgaac
    16801 atcaaacgca caacaagtga acaacaagtg cacacaaaca agaatgaaaa gaattataag
    16861 aatgaaaaga ataataaaac atcatcgtcg caaccacgca aaaagcgtgt ttacgacacc
    16921 gactcagttt actacattct cgcggaggag ttattcaaac agatttgtca gaatcaggaa
    16981 atcaaaaagc cgaatctgca aagttgggca gatgacattc ggaaaatgat cgagatcgac
    17041 aagcggaccg aaaaccaggt acggggaatg attgaatgga gtcagcacaa tgtgttttgg
    17101 gcatcgaata ttttatctgc taaaaaattg cgagaaaaat acgacacaat ggcagcgcaa
    17161 gcaaatcgtg attataaaac aaaacaaact aaaacgcttg aatacgagaa atttagcaca
    17221 gatgagttgc ctatttgaga ggaggcgtag gcatggaaac tgttggggaa atcatggaaa
    17281 agctgataca gaaagtgctt gtccaacgtg gcgaatgtcc tgaatgcgga cagcctttgt
    17341 atggatggcg tacgaagaac cctgatggct cagaacgttg taagccaacc tgtatgcaat
    17401 gtgggtataa agcattgcga gttcaggaag acttacaaac agaacgaatt tacaacgaga
    17461 gcctgaaagc aagagcaatc aattttttca aaggtggttc tgttgtgcct aatcaagcgt
    17521 tgtttgattg cacattgcag aattatcaaa ttgtcgatca agaaacaaga caagcggttg
    17581 aagtaaccaa acgctttgtt aattcagtct tgttaggaaa tccaagtcac cttgttttaa
    17641 ctggaaaaca aggaacaggt aaaagtcacc tagcgatggc agcggcttgg gaagtcttga
    17701 agcgatcaaa ctacgataaa aaaatcttat ttatcgggtt acaggaaatg ctggatcaaa
    17761 tcaaattttc gtacaacaat cctgaactca gaaaaacgat tgagggatcg ttgattgcag
    17821 atatcaaaac agcggattta gtcatcattg atgatatcgg ttcagaacta ggaaaagatg
    17881 catcagatag tcgagcgttt ggcataaaca cgctaaattc gttcttggat gcacgacaga
    17941 acctagcaac gattatcaca acgaacttgc ttggtgaaga actgaaaaaa gcttacggta
    18001 cgagaacaat atcaagaatg tttgtcaact ctgatggatt tacgatggta ttttctcaaa
    18061 cagcagacaa gcgcataaaa ccagtcaaag gagcgatcgc atgaatttga ctaaacaaga
    18121 aaaaagaatc tgtcgtcaga taatgttgca aattataggt gatcgtgaca tggacgaatt
    18181 atctcaacaa gagagtcgaa tggttcggaa gataagtaag ctaattattt atcgggatac
    18241 agaaagattt ctcactgttt taggtaacgt ctacgagaat ccagagttat tggaggtaga
    18301 gtaattgcca aaaatattag atgcatgttg cggtagtaga ttgttctggt ttgataagaa
    18361 caattctgac gtaacattta tggattgtcg tcagcagtat gaagaattat caacaggtca
    18421 tgtgatcaat gttgatccag atgtggtcgc agactttcgc gatatgcctt ttgaagatga
    18481 tgtgttcgat atggttgtat ttgacccgcc acacttaaga catgtcggcg aaaactcatg
    18541 gcttgccaaa aaatatggaa aattagacga actttggcca gaagacatca ggcaaggttt
    18601 tgcagagtgt atgcgagttt tacgaccttc aggaacatta atttttaagt ggaacgagga
    18661 acagatacca ctttctgatg tgttagaggc tattggagaa cagccattgt ttggtaataa
    18721 acgaagcaaa acacattggc ttgtgtttat gaaaaaattc agctaacgga ggaaacaaag
    18781 gaggaaaagt aatgaagatt gtattaaata aatgttttgg tggctttggg ttgagccatg
    18841 aagcaaaaat ggaaattttt aaaagaaaaa atattgaagt attcccatac atcaataact
    18901 ttagctatga ctcagatgat gaatacacga gatacacagg ccaaaagcta ggttcgatgg
    18961 attttatcta ctatttcaaa aaagacccga aaatcgacaa agttacagga atttatagcg
    19021 aaattgaccg actgtacgga attgctgatg attccagttt ttcaagtgat tcaaacagag
    19081 gtgataagga cctcgttgct gttgtcgaaa aactaggaag tgaggccagt ggaccatatg
    19141 caagtcttaa agtcgttgat atacccgatg gggctgagtg ggaaataagt gattatgacg
    19201 gcgttgaaac tgcacattat ggttttcaaa caggtagtat ttagtccact aatgacaact
    19261 aaagaggagg cagaaggatg agtgaagatg aatactttga acagtagtct attaacgaca
    19321 gagattttta actggaaagg ggtgtagtca tggacgcatc ggaagtagta aataaaatta
    19381 atagtctcaa agaggttttc ggagacgtcg aagtagtgat aaacgcacaa ggctatgaca
    19441 acgaattttt taagcagatt accgacatta gcattcagca aggaatggaa gacgaagacg
    19501 gaaactttat cgatgaagta gccattttag tgacttgcga gtaagtaatt gacagctaaa
    19561 gaggaggaag cggaatgaaa ctaaaagacg gattttactc cagcggccac ggcatcggcg
    19621 gtttaatgct agatatgccg acaaagaatc ctaaaacacg taagaaacca aaattcaaag
    19681 tcggtgacat ggttcgctgc gaagcagaag gattcatcta tccatttcgt ggatatgtag
    19741 aacacgtcta taatcactca gcaatcattc gcattgaaaa cacgatggaa tgtgataagt
    19801 ggttagcgaa aagcaaagag aatttagcag tggtgagatt ggtggacatg gaagttataa
    19861 aatcttaatt ttgctttttt acaactatcc tacaacaatg agcgttattc cacaactgga
    19921 aggagaagag gcaattgtga acattttaga gaatatagat attaagcaaa caaggaaaaa
    19981 tgctagacga ttactaaaaa gatacagaaa tttagaacgt ttggtcggac cagtgaaaat
    20041 agacttttcc gtgatgactg ttaccaaaaa tttgaaattc acaattgaca gtcaaaacga
    20101 agaaatcatt gaagcgataa gtactcgaga ttcggttatc gaagcattaa cacggctaag
    20161 tagaatccat ttccaggtac tttattatag ttattgtttt cctaataaga tgtcaatgta
    20221 tcaaatagga gaaaaattag gatattccga tagaactatc gagagaatga aggcagtagc
    20281 tttggttgaa tttgctgagg cgtataaatc aggagaactc atttcacgta caaaataaaa
    20341 aaagtcggat tcctccgact atgaataata tttccgacat aagtattata tcataattgg
    20401 gggaatcaga ggatggtact tttcgatgta aagaaatatg agacaccaag cgcgaaagat
    20461 gttgatatgg aacgcacaaa acataatgtc gctgtgtttc tttcagcata tctatcagct
    20521 agatgtagag tagggcaaca tcgagaacca aaagtgacag catcttattc cttggttcca
    20581 ccttctacag ctgatcatat atttgaagca gaaagaatgc tgatcgataa agaagaagca
    20641 caggaagaat ttgagtatct gcataaattg tttgttcgag gctattcagc gatacagcat
    20701 ccgcataagc ctgatgtgac tgaaaggcgc aagaagatat tctatgatcg ttatatcaat
    20761 ggtctgccca tttatgtaac tgctcaaagg aataatacta gcgaagaatc ggttaaagta
    20821 gaatcaaaca gaattatcat ccaatttgct tcatcgttag aactggttgc tttcaagtag
    20881 ccagttttta cactttttat acccttttat taccaatttg gtttccattt tatacctttt
    20941 ttataccaat cacttaccta ttcaacgttg tattatgata gtgtcgaaaa attaggaaac
    21001 aggatcgaca aaataaaatg taagggagga aatctccctc atcgtttaat taagcttcga
    21061 taggcagcaa cggaaatatt aagaataagg atgtgaattt caactccttc taaattgttc
    21121 ttattatcta tcatccgttg ctgtctattg tttttttaat tattcacacg ataactaaag
    21181 gtaagtgaag agaaatgatt ccattaataa tttcaatttt tgcgctttgt cttaatgtat
    21241 atatgattgg atttaaaaat gggcaaaata aaaaatagta gcagccaaga ataattttat
    21301 agtgtcactg tggcggaaag ggtagacgct aagcatgtgt gctaggtcaa tgcttcggca
    21361 accatgcaag gttcgattcc ttgccagtga ctttggcaac cgaggcatcg gcggtttaaa
    21421 aatatagggg tgcgcaattt cgtacgcgtt ttgtgcatcg tgtaggttgc tattacataa
    21481 ctggttaggt tagattgaga tttgggattc ggtacaaatg aatcgtcaaa tgtctcaagc
    21541 acaggatcgg aaacgtccct gcctgtgcat tacatattag atcactcttt gagtggtctt
    21601 tttctttaca taaaggaggc tacataatga gaaactactg gtatgtatcg ctaactaatg
    21661 aatatcctcg aaccattgat gattgttcag tgcgtgttgt gcgttctgta caaatcaaag
    21721 ggaagtactc tattgtcgaa atggggagag aagcagaacc atgtgagatt gatgcgtgca
    21781 agctcgttta ttgcggtcat ggtttctatg atgaaccaaa cattcaaaat aatattaaca
    21841 agaatttgag ggattagaat gcaagaaatg gcttaaaaat ctccaatcag gacaaatcaa
    21901 gttagacaaa gtttccgatt taaagatatt gattgaagct gatttaatgc taaaagatat
    21961 tgaaaattag aaaacaaaac tcaacctaaa cagaatgtga ggtggtgtgt attgaatggc
    22021 aagacaacgt gatccaagac gtgatgaagc caaaagaatt tggttagaat ccaacggaga
    22081 aaagcagtta aaggaaattg catctgaatt aaatgtttca gattctcagg ttagaaaatg
    22141 gaaatcgcaa gacaaatgga gcgctgaatt gattagtaac gttaccaatg gcaaaagtaa
    22201 cgttactaat caaggtggcg ctcctattgg taatcaaaat gctaaaggta acaaaggaaa
    22261 tagccgagct tctccgccag tgggtaataa aaacgctttg aaaacaggtg agtatgaaac
    22321 aatatttttt gacacgttaa ccgataatga gaaggacatc tattctagtt tgaatgatga
    22381 tccttctttt gctttgtccg aagaaatacg acttcttaaa ataagacaac ttcgaatgat
    22441 gaaaagaatc caacaagctg aagctggact aaatgatgaa gaagtcgaac gattgcagca
    22501 gctaagaaag attaaaactc cgattgaaaa aaatggtaaa aagctagaaa tcaagcgtga
    22561 ggttatgcaa gatgtgcaga ttagcagaaa aaaacatcgc aaaattgatg atattctttc
    22621 aattgaagat tcattgactc ggattagcaa ccagttagct aaagccatca agcaaatgaa
    22681 tgaactttat atgaatgaat acagaactga tttaattaaa gctcagactg ataagatcca
    22741 agctgagaca aatgaaattg gcggaaataa ttcaggtgaa gaaatagaag aatggaaaca
    22801 ggcagtttta aatgccgcaa acaaacgggc ggtgaaagaa aatgaataat gaatttattc
    22861 cttttgctga tattggttct gccattgatt attactatga taaaccagta gctttttgcc
    22921 aagatatttt gcatttgaat cctgatgaat ggcaagaaaa tgttttaaat gatttagctg
    22981 aattttcaaa ggtttctgtt cgttctggtc aaggagttgg aaaaacagca ttagaagcag
    23041 gagcaatact ttggttctta acgtgtcgac cctacgctaa agtaatagca acagctccga
    23101 caatgaagca actttacgat gtactttggg cagaggtagc taaatggtta aatgatagct
    23161 tgatcaaaaa cttactgaag tggacaaaga ccaaaattta tatggttggt gattcagagc
    23221 gttggtttgc tacggctaga acagcgacta aaccagaaag tatgcaaggt tttcacgagg
    23281 accatatgtt gattgtggta gatgaagctt ctggtgtgtc tgatccaatt atggaagcta
    23341 ttcttggtac gctatcaggt tttgataata agctgttgat gtgtggaaac cccaataata
    23401 ttgaaggtgt cttttatgat tcccataatt cagaccgtga taaatacaga gttcataaag
    23461 tatcaagcta tgatagtaaa cgtacaaaca aagacaatat agaaatgatt cttaaaaaat
    23521 atggaaaaga aagtgatgtt gctcgtgtcc gtatttttgg agaatttccg aaaggtgcgt
    23581 tggattcatt tatcagtctt gaaacagttg aattggctac agaaaaacaa attagtgatt
    23641 ctttagtcaa taaaacaaag gttgctcata ttggtgtcga cgtagctcga tatggtgatg
    23701 attctacgat tctctttcct agaattgcta ccagggcatt ggagtatgag aagtattcaa
    23761 aacgtagcac catggaaaca acaggatatg tcatcaacat ggccaagaat ctaatgagtc
    23821 aatatccgag tattgataaa gtgatgatta aagtcgatga cactggtgtc ggaggtggtg
    23881 taaccgaccg cctagaagaa cttatagaag acaaacatta tccttttgag gtgtttggag
    23941 tgaataacgg ttcaacatca gaagacgatt tttacgataa tttaggtact caactatggg
    24001 gaaacatcaa ggaaatgtta gaagaaaata tgacagcaaa tcttaacgga gaacagcctg
    24061 ttattgaatt gccttctgat agttcgttaa tcaaagaatt aagtactcgc aaattcaaaa
    24121 tgacaagtag aagtcgtata cgtttagaaa gtaaagatga tatgaaaaag cgaaatattg
    24181 gtagtcccga tattgctgac gcactggctt tagcgtttta tgagccacca agtcactatc
    24241 aatttattca attttaggag gtgagctttt gattagtaca gtattatctt tagagagata
    24301 taagaagcta cgtgttaaat atgcaacaca aattgaagat ggaatgtttg atccgaatgg
    24361 ttttatagaa gatatgaaac cattttttgc tgatcgcgaa agaaaatatc tagcttatac
    24421 tagcgaaaag aatgaaatag ataatagacc aaagcctaac actgatattg taaaagttaa
    24481 taataaactt catgctggta tgtattcaat tgtcgtagac caagcagtca atcattttac
    24541 tggtatacct atcaaatggg attacgatgt atcggaacaa aaaagaacac tcattcaaag
    24601 attaaaagat aaattcttaa aaaatgatat agaacttccg acagttccag aagcttttaa
    24661 caaattaaca agcaatcttg attccatgag attcgcaatg cttgattctg aaactgcaac
    24721 ttttcaagga gcttgtggag tagctttccg attgctagag cctgtggaag aagatgatgg
    24781 ttggaagtta agagcaagta atattgaacc ttggagagca gaaagatatg gaaatgccgg
    24841 aatctatatc aaagaaaagt atgactctta ccagaaaaaa ttttttcaag aaatgaaagt
    24901 tatgacaaga aataaaattc tgacatatgc ttgctatggt gatttgaatt ttgttacaag
    24961 cggaacgttc aaaaaaattg atgagaccga taaccctttg gggacgatta ccttggcaga
    25021 atttaaaaat aatacgaatc gttattgtga ttttgaagta gctgaggaaa ttggagatgc
    25081 aattgatcgt gctttgtctg atcaacaaaa cgaaatcgaa caatttaagc ttgcgtacat
    25141 gcttgttact ggcacaacaa tgagcaaagg cactgctaaa gaaatgatga atcagctagg
    25201 gattatcaac ttaaaagccc ctactgcaaa agctgaatat gtcacaaaaa atttagcaaa
    25261 agatttcaat gaatatcata tggatctatt gaaaaaacag ttttacacca tttgtaaagc
    25321 aatcgatttt aacgatgagg tgtttaaatc aaacagttct ggagaagctc gcaagtggca
    25381 aatcattagc ctagaagcga aaacaaatac taaagagcaa tattttagag aaggattgaa
    25441 agaatgcgca gaaacaattg ctgcttttct taagtttcat gacaaagtag aaattgagcc
    25501 tgaaaaaatt atttttactt tctctagatc tttgccaact gatttaagtt atttagctga
    25561 agctttacct aaacttgcac catacgtatc caaacgaact attcagagcc aaattccatt
    25621 tgtaacagat gttgattatg aaaatgaaat gatggaattg gaaagtggaa gtgcttatcc
    25681 agatagtgaa tacaattttg gcggaggtgg caatagtgac gatagaaacg aagtattgga
    25741 ccaaacgtcg agaactggag gatcaagcaa ggctcaaaca agaaaatcag acacttaaaa
    25801 aattaactag tgtatttcct gaagcactga aagagataca agcaaaacta ttatcacaag
    25861 ctgacttaca caatatcact tatccagaaa tgatggagtt ttacagtaca agtaatcaga
    25921 aaaaatatcg tgaatatgtg gaaaaaaatt ataagtcatt aaaaatgtat gatgcaaaat
    25981 acaaagagtt tatcgatgaa ttttttccac catttgacta tgcaaaagtc aatcgcttat
    26041 tacaaatacg atcagatgta tttaaaattc ttgcagaata tgcgatggat gcagatgtga
    26101 atcaatattt ttctgatcgc ttagaggaaa ttcttcaaag aacatattct tctaatgcta
    26161 atgtttttgt tcaactttta aacgttgata taccaaatta tttaccagaa aatgaaatta
    26221 aacattattt gaactatcca tggtcaggaa agacattttc aagaagactt tggggaaata
    26281 tttcatcgct tgaacagaaa ctctctaatg ctattgtaaa aagtgttgct agtggagaag
    26341 gcgttataca cgcattaaac accatgagat tagactcaga aatttgtgac atgtttaagt
    26401 tagaagaatc aaagtataac aaagcgatag aaaatctcgt tcgaacggag tatgcaaaat
    26461 ttgcacaaga tggtattgaa aaatcatatt tagaaacagg tattgaggaa tacaacgtat
    26521 tgactgcaaa agatgagaga gtttgccgga tttgtggagg aaaggcaagt aagaatccct
    26581 ataaactgaa agatgctgtc ataggtgaaa atcgagcacc tttccatagt cgttgtagat
    26641 gtacggatgt tcctaattta ccaaaattag gaaaggatat tgatgaagaa tatgaccgtt
    26701 tatttggcga tttattagat gagtttgcac atgattcttt tggaattaat ttgaaacgga
    26761 ggaagtagaa tgaaagattt ttttgaagca gtactaacaa ttaatgtaaa tgctgatatt
    26821 gcagaagcct acaaaacagc tattgagtct gagaaccatc ctaatggctt gagagaccat
    26881 tggaatggca attatgccta cgtggttatt ggcgatcaaa ctgttaatta tcaagataat
    26941 actccagttg ataagaatac cgttaattta acgattcaat tattatctca ttcattacca
    27001 aatttaaaag aaacagttga ttggtatgaa aagatgggat gtattgttgt tagaactgac
    27061 tacaaagaag gaaagtctag taattaggct tttttatttt gtccgaaatg acgttaaact
    27121 agcgcaatac tgggcttggt tgaatggtgg ggcgcaacta ttaaaactca aagcaatgcg
    27181 gggcgtgaaa acgaatcgtg gggcgaaagg agaatgagca tgaaacacaa atcattaatg
    27241 ccaatgaatt tgcaatactt tgccgaaggt gacgatcaaa agttttcttt tgatgacttc
    27301 aaatcttttg tggaatccaa tgaagaagct caaaaattta ttcagtcaca atctcaaagt
    27361 gttgccgaca aacaattgga agcttggaaa caaaataact tagataaaat taaacaggat
    27421 accatcaagg aatatgagga atctaagaaa aacaagtcac ctgagcaaat tcaactggaa
    27481 aaactacaag ctgaatttga agcagaaaaa gcgttgcgtg tgacaagtga taataaagca
    27541 tttgttgcag aacaaattgc tggattagaa ctagatggag agttaaaaga gtctatttct
    27601 caatttatgc taaataatct tgttagttcg gatacagatt tcactaagaa tgctgttgaa
    27661 ggttttacaa gtgttttgaa tgcaattaat gagaaacatg cagatgcatt aaaagaacta
    27721 caaatgaagt ctgcatttgg tggaactcaa caatcgaata accaggttca gcagaacaat
    27781 gaaacattaa caaatccaga agaacaatta ggacaaattc ttcaacaatt taactaggag
    27841 agtgaaaaat tatgaaaaaa acatctttaa ataatttaga gtatttggat atttcaccag
    27901 cgattaatgc tatgcaagta ccaaatacac cttttttaag ctatttactt ggtgctggaa
    27961 aaacagagcc agcaaactcg acagaaatta aatggcgtga atatgatatc aacaacgatg
    28021 attcttctga aaaacttgag ggcggagaat atccagatgc tgaatcaggt cgaacttggt
    28081 ttaacaacta tactgaaatt tttagaaaat caacctctgt atctggtaca ttagatgcta
    28141 ttaatgtgaa tggagtcgga aatgaattaa ctaatcaagt agcactacgt ggtatggaaa
    28201 tgaaaattga tttgaaccga aaattgatta ctggtgtaaa agctgatgaa aatggttcta
    28261 aaggtcgtcg aatgaatggg attttgaact tgatcaattc agcaaataag gcagaaacag
    28321 ccactgcggg tgcagtaaca agaaaagata tcgatacttt atttaaattg atgtatgaaa
    28381 aaggttatat gggagaaaaa ctatgcttga tttctccaga tatgcaggag ttaatgactg
    28441 atgagttaga tggaaaatca acaaaaattg ttcagttcgg ggaaagagta acttttggat
    28501 tgcaaattgg aaatatcgtg tctaattacg gtacaggtat tgctctacta gaaccatcat
    28561 tgccaaaagg aacaattgcc gcaatcgata ctaattatgt gaaactacgt ccattacgtg
    28621 aatggagagc agaagaactt gcaaaaacaa cggattctag acgtatcggt cttgtaggtg
    28681 aatactctct tgaatacaat gcttcaaact ctggggcaat tttaaattta aagtctgaat
    28741 aaaagggagt tagtactccc ttttttgata ggaggaatta cagtggtaaa aaaagatgaa
    28801 actaaaaaag atgaagtcgt gaaatataga gtaggtaaaa ctaaaaattt tgttgggttt
    28861 gttcatccta aaactcgtag atttatcaca gcagattcaa ataacgaatt tatcatttct
    28921 atagatgata aagaagcaat tgcaattttg gaagatgcaa ttgatgttaa tgaaatttag
    28981 gaagtgatct gatggatgaa tcgctaaaaa cggaaatcat tgagtctaca aaagaagatt
    29041 ttccagattt gagtgaagaa cgcataacta atttattaga aataattttg ctagaaattg
    29101 aatcatacaa cacttgtaaa aatgatattt catgggaaaa gttaaaaagc gtgattagtg
    29161 aagtgttgta taaaataata aaaaatgaat cagaaaaaac agtatcttca gttagacgtg
    29221 gcgatacaac gattagttat gcttcaacaa caaatgatgt tagtgagtta cttctaggct
    29281 atggtgattt gatacgaaga gttattggtt gtggaggatt ggagtttttt taatgaatga
    29341 agcagatatt ttagaaacta cttatgaaga tagttgtatt attgaaagac tgacggacat
    29401 tgaagattct aatacaaata ttactattca agattacaaa aaagtatatg ataatcctat
    29461 ttcttgcgct ctttcacaag gtcaaatcga tggactagca gtcatagaag atggagagat
    29521 ggtaaatgtt tcaactgaca catataaatt atttgttcat cctaagatta aactaaaaaa
    29581 aggagatcga ataacaataa ctcaaaaggc cagtggctta attttttctc tatttgctac
    29641 taagcctttt tactatccta gtcattgtga agtgaatttg ataggaagtg agaaaaatgg
    29701 gtaatctcaa atatgaatca aatgcagaaa agatcattga gaattttaaa aatatgactg
    29761 taattgctca aaaagaagga atatccttcg ttaacgattc aatgaataaa gtcgttagtt
    29821 tagctaaacc attaactcct gtaaaatcag gtaatttaag gcgaggatat cgtgtagtaa
    29881 aagctagaaa actatcaagc ggtcgaattg ttggagaagt tataaacaat gaacattatt
    29941 ttaaatatgt agaagaaggt cataggacta aaaatggtgg ctttgtcaaa gggaaattca
    30001 tgttaactcg tgcaacgaat cttgcaaata tgtcttatat tcctcgaaga tttaaacaaa
    30061 tggcaataaa aatcgttaag aaaggaaagt aacatgaaag atgaaatcat tgctgcaatc
    30121 agtagcaaat taaaagaaat ctatcctgat gggacaatat atcttgattc agttatgcag
    30181 tcaactaaag atttttattt cgttttatca gtaatggaat ctggaactga aaatgtagga
    30241 attgatattc aaaatgtttc tttcttaatt gatattgcat tgattgataa taaccctaat
    30301 agaaatttaa ttaatgaatt agtctcacgt tgtgggactt tttttaatac gattacaatc
    30361 gatgagcaaa tattatttcc aaaagcctat ttacctgatg aagcagatgg tgttcaacat
    30421 attcgtttta cattagaatt tccacaatat attgaatgga gtgaaagata aatgggagaa
    30481 aaaagaagta aaaccggaat tatttctgtc gaaaaaccta cttggtttcc tttggaagat
    30541 gagacaggga attttccggt atatggtact gcgttgccaa tgggaacagc agtaagtatc
    30601 aaaccaacag ctaattatga aacaacacaa gattatgggg attcagtggt tcaagatcaa
    30661 tttacagctt ttggtggtgc agaagttgaa ctggaagcaa atggatatac tcataaagtt
    30721 ttatctacaa ttactggagg gaaaattgtt aaaggtggtg ccttgcgttc tggagaagat
    30781 attgcgcaag atggtgcgtt tgcatataga cgtaaaaaat cgaatgggaa ataccgttat
    30841 acggtctttt ataaaggaca gtttgctcta gattcagatg aaacatcaac gattgaagga
    30901 agtaaagtaa gttttactca tccaacttgg aagggttcat ttgtagatgt accaggactt
    30961 ggatatatgt attcagttga tgaagatgat gaaggcgtgg ataaagcaat gatcggaaat
    31021 tggtttacaa aagtagcaat tccaattgaa gaagcagaac tttcaggagg tacagaataa
    31081 tgtcaaaata tcaaacaacg attaaattaa cgaaaaaaga cgaagaaggt aaatatgagc
    31141 aagtacaatt taaatctgct gaatttttac caggaacagt tgtagaagat gctgcaggag
    31201 ttatggaaga aatgcaaaca gcgactgata agcaatcagt taaaaaagct ttaagtcgtg
    31261 cttattcatt tattgcagat actttatttg agggacaatt tactggtgaa gattattgca
    31321 aaggaattga tgctcgtgag attgcctcat tgacaggaaa attattgaag tctgttactg
    31381 caggttttga tgaaacttat acagagacga aaaaaaagta agtgaggcgc tcaagtcacc
    31441 ttcatttaag tattcgatta cttaccgaga attagatata aagacgcaat tactcgaagc
    31501 aggttggacg ttaccagaaa ttgaacgtac tgacttggat gagttaatgc gtctttttgc
    31561 ttttagagat gcggtaaaag agcatgaaga tgttgagtac tatgataatt tcactcaatt
    31621 ttaggaggtg atactttgaa taacgatgac ctaattctga agatgatact agatgaatct
    31681 ggttttactg ccggtatgaa taatgctgtc aaaaagttga actcttttga tgaaacaatc
    31741 gaaagaaaaa gtagaaatag tggcagttca ttaggtagta tttggaaaat atttgctgga
    31801 agttttctag ctagcggagt aactagaatc gtaggagctg gctttgatct aatcaagggt
    31861 tccataagtg gagcggttga tcgagtagat acgatgaata acgctctacg aaatttccaa
    31921 aatatgggat ttagtaattc agaaattatg aagaatatcg gaaagaatgg gcttttatct
    31981 caaggtattc aaggacttcc tactgctttg aatgatgcga taagtcatgt tcaacttctt
    32041 gcttcttcta caggtgattt aactcgttca actcaaatat ttaaagcttt aaatgatgga
    32101 attcttggtt tcggtggttc aactgatcaa gttaatgaag ctgttattca attatctcaa
    32161 agtttctcaa acggaaaagt agacgcacaa acttggaact caatgatcaa cgctcaactt
    32221 ggacctactc tttctgctat tgctaaaaag atgggaatta caatgggaga tctgaaagaa
    32281 ggtttatctc aaggtaagat ttctgttgaa gaattccaaa atcaattaat agaaatggat
    32341 accaaaggtg gcggaggact taaatcatta agtcaaatcg ctaaagattc tactaaggga
    32401 attaaaacct ctatacaaaa tgcaaaaaca gctgttacac gtggtgttgg tgaggtaata
    32461 gaaggattaa ataaagcatt agtagattca gatttaggtg gatttaaggg aattattgat
    32521 aaagtgggca gttcaatgga atcgttctta aaagtaattg ctgcaaatat tcctacagca
    32581 gtatcatttt taagtaattt atttaacgaa attcaaaaat ttggttctgc tttgaaattc
    32641 atgatgccct ttcttgttcc tgcagctacc gcttttggag cgttcatgtt tcaacttaaa
    32701 ggtataccag caataataaa aagcttcaat aattttaaga atgccataat tggcgttgga
    32761 aattcattaa agattatggg ggcaatagct gctgctaatc catttgtttt aattattggt
    32821 gcagtcgttg gtgcaatagc tgttttcggt tactttatgg caaccaatga agagcttaga
    32881 aacaaggtta tatctatttg gaatgatgtg aaagattccg taattggtgt attaaaaaat
    32941 ataaaggact ggggaattga tacttggaat tctgctaaag aaatggcatc aaatgcagtt
    33001 gagggtgtca aagatgcttg gtcaggaaca aaggaatggt tttctaacac ctggaaaggt
    33061 attaaggatg gggccacagg tttatttgat aaaacagtag agacttcaag aaatgcagtc
    33121 gatagtgtaa aaaatgcatg gtctaatatg aagaaatggt tttctgatac ttggcaaagt
    33181 ataaaagatt cagccagaga aaaatggaat ggaatcaaag gttctattat gtcagttgct
    33241 ggtccattga ttacaggtat aaagaatgca tttttacatg ttacttttta tctagagacc
    33301 ttatggaata atttagttga gattggtaaa aacgtctttg agatttaaaa aaatgttata
    33361 cttgcgccgg ttttgtttat tacctccatg atttctggtg gatgggaaga aacaaaaaat
    33421 aatatgattg ctgtttggaa taatattaaa gaaagtgcca taaatatttg ggaatctata
    33481 aagaatatat ttgtaagtta ttttacaaat atttattttg ctgcactcaa tatttggaca
    33541 gggttcaagc ttacattgat aaatatttgg aatgaagtgg taaatcaagc taaatcgatt
    33601 tggttaaaca taaagtattt ttttattaat ctttggattg atataaaata ttttgcaatt
    33661 cagaaatgga ttgaattgaa gttttctatt attcaaactt ggatcgattt aaaatataat
    33721 gccattacta cttggaataa tattaaacag tttttcaaag atacttggaa aaatattaaa
    33781 gatacggcat acaatacgtg gatttctata aaaaatacca tgattaatac atggaataac
    33841 attaaggact ctttctggaa tattgttact ggaattgtta attctgctga aaatgcatgg
    33901 acaaatctaa aaaatggtgt ttcaaatgct attaatcggg taaaagaaat ctttaattcg
    33961 ttaagggaag tcaatttatt tgaaattggc aagaacatca ttgatggact tataaatggt
    34021 gtaaaagaaa agtggaatgc tttgaaagat actatcaaag gtattgcagg taatatcaaa
    34081 aattggatta aaggagcttt agatattcat tctccatcaa gatggatgcg tgatatggtt
    34141 ggtaaaaata ttgttcaagg tattatcgtt ggtattgata aagagcaaag taagttagat
    34201 caaaccatga caaatttagt aaaaacaccg tctgttcaac ctgtagtaaa tggaataagt
    34261 cacctaccaa ttacacaaac aaagcaaaat atatctgcta gtgaaacaaa agaaattcat
    34321 ttacatttaa atgtttatgg agatttacct gattcaatgg ttcggaagat taccacaaaa
    34381 attaaaacag aattgacaag acaaatgaaa cgagatgctg gtgcagtagg aggaacatta
    34441 tatgcaactt aagagaggac aattttttat taatcaacat tattcttctg aatttaatgt
    34501 gtatattcaa aacaggcctg cttctgtttc agctagtcga gtaattgaat tgagagagcg
    34561 agaaggaaat gattctatca ttattgataa aggctattac aaaaatgtga ctagaaagat
    34621 tgagtgttac tataaagcac cttcaattga tatggtgcag gagtgggaag atcgaatcac
    34681 tgaatggtta gatatgtcgt cttatagtga ttttattctt tactatgatg aacaatatat
    34741 ttatcaagct gtagtaatag aaggacctga atttaaagga acaagaaaaa caggaaatat
    34801 tgtccctttt gaatttacag tgagtattcg accatttaag gaaaattaca atggtagatt
    34861 tactattcga caaacagaaa cttttgaaat ttataaccca gagaagtatt cttcaaaacc
    34921 gcttattaaa ttgagtggtt ctggagatgc ttctttttat attaataagg ataaatatga
    34981 tttgaaatcg ttggacagag aattatttat agattctaaa ttagaagagg cttatcgaaa
    35041 attagatggt aatttagaac atcaggatca ggtcacctta tttttagatt ttccattttt
    35101 atatcctgga aaaaatgaaa ttaaatggac gaaaaatatt cattcatttg aaataatgcc
    35161 taggtggtgg agaaaagtat gaaaccaaga atatatagtc ctactgaaac agatttctca
    35221 acgaatggct taggaatttt aaaggattgt acaagatgtg gaatatatga agtagctaat
    35281 ggaaaatatg aattagagtt ggattatcct ttaggaacta gatttgatga atattttgaa
    35341 aatgactatc aaataaaagc aaagccaaac gatcaagaag agtatcatat cttttttatt
    35401 gatgataaag atatagatac ttttttaaat acagtaacta tttatgctca gagtcgtaca
    35461 aatcgacttg gaagacgggt agtcactctt gtggaagtgg actctaaaac tggtcaagaa
    35521 gcgatatcaa ttattgaaac taaaatggat aaaaaatctg acatacgact ttattctgat
    35581 attacggctg tttctagcac aatctttgaa gcgagaaatg ttttaaattg tattgctggt
    35641 gaacaaggat cattgcttca atattggggc ggagaaatta aacgtgaacc atttaagctt
    35701 tctttgttaa agcgaagagg tcgcaataat gttggaacga ttcggtatgg aaaagatatg
    35761 tctggtttga aggtcaaatt agattggaca ggtataaaaa caagaattat tccatatgct
    35821 gatcctcaaa gtgaagtagg tacgactaat cgaatttatg gttcgccagt agatagtgcc
    35881 tatattaata actatcctga tgtctataca gaacatgttc agtttacaga agaacaagga
    35941 gtaaaagaca ttaagagctt aaataaaata gctaaaaatt actttaaaac gatcaatcct
    36001 ggctgtgata agcctaaagt ttctattacg gttgaatttg ataagttgac tgatagtgaa
    36061 gaagcgaaag aatttgcgaa gattagaaat tatggtctgt ttgatacatt taaaatatat
    36121 cataaaaaat ataatattta tcttgaatca aaggttagtg gactacaata cgattcttta
    36181 tctgaaaaaa ctttgaaatt agaagcagga gacattcaag ttgcttttta tcagcaacaa
    36241 gctgtaacta ttcaggataa attaaaagat tatgcaacga ataattatat gagtgatttt
    36301 aatgattatg tttcttcaat gattacaggt caaggcagtg caggaggata tgtagtttta
    36361 tggccaaaag aaaaaccttc caacatcttt attatggata atccagattt agaaaaggca
    36421 agagaagtac taagaatgaa taaaaatggg attgcttttt ctaagaaagg atggcggggg
    36481 ccttttaatt cagcttggac attagatagt atatttaatg ccaattttat acaaactgga
    36541 ttaatcaaag cagatatctt tcaaaattct tttaacaaga ctggagatgt attgaaatta
    36601 gttaatggac tactccaaat ttggaacaac aaaaagaaaa taatggagtt aactaaaaaa
    36661 ggaatggaat tttggaattc taagggttca attggaacga ttggaacaac tgattctgtt
    36721 ggtaatcctt ttcctggggc ttctactcca acccctattg aagataattc tttagttatt
    36781 cgtacaaatg gagacggcaa atatattttg atttctccta aagtaggaaa aggattagtt
    36841 ttattaggaa atggtaaagc aatttatttt ggagacttag atgtacaagg aaaacttaca
    36901 gttaaaggaa aagaaataat tcctggacaa ggtggtggtc catcgggagg tggagaatct
    36961 actggtgggt atcctagtga attaaaaaca gatgcagaaa agagagcttg gagaatttac
    37021 gatattttgt gtaataacgg atttacgaaa caatctgcat gtggaatatt ggggaacatt
    37081 caacaagaaa caggaggaac ttttgatcct gatactgttc aaataggtgg accagcatac
    37141 ggattagttc agtgggatgg ttcttcatat cctcttgttg gtccagcaac atgggatgga
    37201 aaagtttatg ttcaaaactt atttaatgct gcaggtatta aagaaccaat aacgagctta
    37261 gatgcacaag ttcgattgct tatttggaca tttacaaatg gacaatggat gggcgtagta
    37321 caacctacga cggttgatgg atttaaggcc tgtactgatc caagacaagc agcatatgct
    37381 tttgaacgaa actatgaacg tccggcagcg acacatcctg aacgtcaaga ttatgcagtt
    37441 aactggtata acaaatttaa agatttaaaa ccaggaggag ctactggaga agcaggacta
    37501 aaacatttag agtctttgat tggacaacga attggcaatg gtcagtgtta tggcttgtct
    37561 gcagaatatt caggatatct gggtggttgt ggcatgggtg ctggaacaaa atatggttta
    37621 actcatgtga taggaaatac ttctgcagca tctgatattg gtattgccta tgattggtct
    37681 gctgttggtt ggaaagtgat tcaaaaccct agatatgatc aattagtagt tggtgcaatt
    37741 attaattggg caagaggtgg acaagtgggt tcatggtttg cagatggaac ttatggacat
    37801 actggcgtta tccgaggctt agctaatggt cgtatgcaaa cttatgaaca aaacacagag
    37861 ttaggtatga tttgtggaaa gttagatcgc cagtattata gtgcaagtgc aatttcttcc
    37921 attgtcatac caccaaaata gggaggtgat ttaatggcaa agtggaatgt catattaagt
    37981 acaacagaac cctataatta cgtggggatg attcaagttc gacaaggcaa taagaataca
    38041 gaggttatgg aagcgactat agttgaaaat ggtcttccct acgatttatc agaatgtaag
    38101 gtatattttg aatcagttgt aggtgggaaa tatccagtcc aattagaaac aaaaattgtg
    38161 gatgctaaaa aagggaaaat taactatatt tttgataaat attccatgca gtgtttacat
    38221 cgacaaacag ccaatttcat tatatttaaa ggagaagact tgattggaac aactcaagac
    38281 ttctcttatt ttgtcattaa tgctgtttca aaaacagaag gagaaatggg ttcttattgg
    38341 caatcaatcg aagatttaat tgcggatatg acggacttta ttaatgaaaa taaaggcgat
    38401 tttacggact ggatgaatga aaggaaagaa gaatttgaac gttggagaca agaacaggaa
    38461 cacagtttcc aagattggag agaaggacaa gaatcagact atttggcatg gtttgaatca
    38521 atcaaggata ttttaaagac gattgatcca ggtggagtca tgttagccga actaacggat
    38581 gcgcgagtag atattcaagg agttcgtcat gcgtctattt cagagcgttt gctggcagat
    38641 atggactatt tatatcagaa attgcgagca acgcttttca cgattgaata cggggagatt
    38701 gaagtgactg atattttgca ggatgatctc ttttcagata atcatgaagt cgaaaaagtt
    38761 ggaactgtag cattcccgat tgaagaagga gccttgatca tcgcaaccgt tgatgatcca
    38821 aagcaaaatg tgttcactct tgagaaagtt ggggtgatct aatggctaaa actaaacgaa
    38881 tgatggaaac ggatgaaaaa acgggtgtac aacgccaatt ctttccaatc acacatgctt
    38941 ccgcagttct tgggttagaa gaaataatag caggagaagc aacagtttta tctgttaatg
    39001 gaaaaattgg agccgtcgtc attactaaag aagatttggg attagagaat gttctcacag
    39061 aattacccta tgcaagtgaa gaagatgacg gcattatcac ggcagaaatg tatcaaaaaa
    39121 ttttaaacag tggagaaggt gactacgtgt tgccagttgc cactatcgac cgtttgggtg
    39181 gcataaaagt tggtgaatta ttgacgattg atgagacagg gaaagtctct gcagtcagac
    39241 aatctgatgt caatttttcg ctggagttaa aagaaaaact cgattcactg aaaaattata
    39301 ctgctggaga aaacatcact attgatgaag atggaacaat tagttctaca ggtggtagtg
    39361 ggactggtgg tgtcaatcag tcatatgtag atcaaaaatt ccaagaagct gtaaatcaag
    39421 cagaaaatta cacaaacgaa agaattccaa attttacttt tgaaaaaatt ggggaggtat
    39481 agagaatgac agatatcgta aaaataaaac aaagcaatgt acaggtttat ccacaaactc
    39541 attggaatgc tatagaaggc aaaccaacaa cggtgaaggg agataaaggc gatcctggcc
    39601 aagcagcaac aattaccata ggaaccgttt ctagtggttc aaccgcttct gttacgaatg
    39661 taggaacatc atctgcagct agatttaatt ttgttttacc aaagggagat aaaggtgatc
    39721 ctggaataaa tgccacaact acagctgtag ctacaactac agcaaatggg ttgatgtcgt
    39781 ccacagataa aactaagttg gatggaattg cagctggagc acagaaaaat ccaggtaatg
    39841 ctacaactac gacagcaggt ttaatgtcag caactgacaa agctaaactc gatggattag
    39901 ccaatattac atttgagaaa gtggggacgg tttaatggct gatattgtgc aattaaaaga
    39961 agacggagtt gctaaatact taaaaacgca tgtagaagct attgatggta aagaagcatt
    40021 ggtgcagaca gatggagacc aagccattgc aggacataag aatttttcag gttctgtaac
    40081 aatcaataat aaacgtgttt tgacgactga tgataacaga tatgaagtgg taaatctggt
    40141 tgtcactaac ggtaatacag ggacagcaaa gctttatcgt gaaggaaaaa cagtttctat
    40201 atattttgtg gctttaaacg gaaaaagtag tggcgggaat gattcggtta ttttaactgt
    40261 tccagaaggc tatcgg
//
LOCUS       DAIGSZ010000020        39141 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.020, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000020 DAIGSZ010000000
VERSION     DAIGSZ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.020"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            212..604
                     /locus_tag="NOB31_001113"
     CDS             212..604
                     /locus_tag="NOB31_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0973332.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="NOB31_001114"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="NOB31_001114"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HCI0973333.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="NOB31_001115"
     CDS             3165..4775
                     /locus_tag="NOB31_001115"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HCI0973334.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="NOB31_001116"
     CDS             5067..5936
                     /locus_tag="NOB31_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HCI0973335.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="NOB31_001117"
     CDS             6101..7372
                     /locus_tag="NOB31_001117"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCI0973336.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="NOB31_001118"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="NOB31_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HCI0973337.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="NOB31_001119"
     CDS             8763..9026
                     /locus_tag="NOB31_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HCI0973338.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="NOB31_001120"
     CDS             9471..9920
                     /locus_tag="NOB31_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0973339.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="NOB31_001121"
     CDS             9977..11395
                     /locus_tag="NOB31_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0973340.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="NOB31_001122"
     CDS             11395..12255
                     /locus_tag="NOB31_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HCI0973341.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="NOB31_001123"
     CDS             12429..13202
                     /locus_tag="NOB31_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0973342.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="NOB31_001124"
     CDS             13349..13714
                     /locus_tag="NOB31_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HCI0973343.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="NOB31_001125"
     CDS             complement(13862..15070)
                     /locus_tag="NOB31_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0973344.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="NOB31_001126"
     CDS             complement(15089..15367)
                     /locus_tag="NOB31_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973345.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="NOB31_001127"
     CDS             15521..16216
                     /locus_tag="NOB31_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI0973346.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="NOB31_001128"
     CDS             complement(16658..17455)
                     /locus_tag="NOB31_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HCI0973347.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="NOB31_001129"
     CDS             complement(17452..18636)
                     /locus_tag="NOB31_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCI0973348.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="NOB31_001130"
     CDS             complement(18661..19908)
                     /locus_tag="NOB31_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCI0973349.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="NOB31_001131"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="NOB31_001131"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HCI0973350.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="NOB31_001132"
     CDS             21888..22202
                     /locus_tag="NOB31_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HCI0973351.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="NOB31_001133"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="NOB31_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HCI0973352.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="NOB31_001134"
     CDS             22887..23531
                     /locus_tag="NOB31_001134"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HCI0973353.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="NOB31_001135"
     CDS             23546..23875
                     /locus_tag="NOB31_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HCI0973354.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="NOB31_001136"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="NOB31_001136"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HCI0973355.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="NOB31_001137"
     CDS             24863..25687
                     /locus_tag="NOB31_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HCI0973356.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="NOB31_001138"
     CDS             25680..26027
                     /locus_tag="NOB31_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HCI0973357.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="NOB31_001139"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="NOB31_001139"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HCI0973358.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="NOB31_001140"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="NOB31_001140"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HCI0973359.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="NOB31_001141"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="NOB31_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HCI0973360.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="NOB31_001142"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="NOB31_001142"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HCI0973361.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="NOB31_001143"
     CDS             31657..32451
                     /locus_tag="NOB31_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0973362.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="NOB31_001144"
     CDS             32441..34483
                     /locus_tag="NOB31_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973363.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="NOB31_001145"
     CDS             34764..34913
                     /locus_tag="NOB31_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HCI0973364.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="NOB31_001146"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="NOB31_001146"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HCI0973365.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="NOB31_001147"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="NOB31_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HCI0973366.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37924
                     /gene="dltC"
                     /locus_tag="NOB31_001148"
     CDS             37685..37924
                     /gene="dltC"
                     /locus_tag="NOB31_001148"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HCI0973367.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKGLV"
     gene            37921..>39141
                     /gene="dltD"
                     /locus_tag="NOB31_001149"
     CDS             37921..>39141
                     /gene="dltD"
                     /locus_tag="NOB31_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HCI0973368.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFF"
BASE COUNT        12566 a         6883 c         8182 g        11510 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggtttagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt t
//
LOCUS       DAIGSZ010000021        38617 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.021, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000021 DAIGSZ010000000
VERSION     DAIGSZ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.021"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            33..656
                     /locus_tag="NOB31_001150"
     CDS             33..656
                     /locus_tag="NOB31_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973369.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /locus_tag="NOB31_001151"
     CDS             1106..2155
                     /locus_tag="NOB31_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0973370.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="NOB31_001152"
     CDS             2152..3033
                     /locus_tag="NOB31_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973371.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILVICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="NOB31_001153"
     CDS             3036..3806
                     /locus_tag="NOB31_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0973372.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="NOB31_001154"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="NOB31_001154"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HCI0973373.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="NOB31_001155"
     CDS             5117..6280
                     /locus_tag="NOB31_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI0973374.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="NOB31_001156"
     CDS             6397..6807
                     /locus_tag="NOB31_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0973375.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="NOB31_001157"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="NOB31_001157"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCI0973376.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9380..9664
                     /locus_tag="NOB31_001158"
     CDS             9380..9664
                     /locus_tag="NOB31_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973377.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9824..10060
                     /locus_tag="NOB31_001159"
     CDS             9824..10060
                     /locus_tag="NOB31_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0973378.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10057..10455
                     /locus_tag="NOB31_001160"
     CDS             10057..10455
                     /locus_tag="NOB31_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCI0973379.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11122..12066)
                     /locus_tag="NOB31_001161"
     CDS             complement(11122..12066)
                     /locus_tag="NOB31_001161"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCI0973380.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12362..13306)
                     /locus_tag="NOB31_001162"
     CDS             complement(12362..13306)
                     /locus_tag="NOB31_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973381.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13527..14741
                     /locus_tag="NOB31_001163"
     CDS             13527..14741
                     /locus_tag="NOB31_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0973382.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14763..16778
                     /locus_tag="NOB31_001164"
     CDS             14763..16778
                     /locus_tag="NOB31_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HCI0973383.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16861..18234)
                     /locus_tag="NOB31_001165"
     CDS             complement(16861..18234)
                     /locus_tag="NOB31_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI0973384.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18260..18544)
                     /locus_tag="NOB31_001166"
     CDS             complement(18260..18544)
                     /locus_tag="NOB31_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0973385.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18546..20561)
                     /locus_tag="NOB31_001167"
     CDS             complement(18546..20561)
                     /locus_tag="NOB31_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCI0973386.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20740..21045)
                     /locus_tag="NOB31_001168"
     CDS             complement(20740..21045)
                     /locus_tag="NOB31_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HCI0973387.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21134..22165)
                     /locus_tag="NOB31_001169"
     CDS             complement(21134..22165)
                     /locus_tag="NOB31_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0973388.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22372..23247
                     /locus_tag="NOB31_001170"
     CDS             22372..23247
                     /locus_tag="NOB31_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0973389.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23399..24241)
                     /locus_tag="NOB31_001171"
     CDS             complement(23399..24241)
                     /locus_tag="NOB31_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0973390.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24333..26210)
                     /locus_tag="NOB31_001172"
     CDS             complement(24333..26210)
                     /locus_tag="NOB31_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI0973391.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26207..27628)
                     /locus_tag="NOB31_001173"
     CDS             complement(26207..27628)
                     /locus_tag="NOB31_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI0973392.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27631..31020)
                     /locus_tag="NOB31_001174"
     CDS             complement(27631..31020)
                     /locus_tag="NOB31_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCI0973393.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYRKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31277..32668
                     /locus_tag="NOB31_001175"
     CDS             31277..32668
                     /locus_tag="NOB31_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973394.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32741..33388)
                     /locus_tag="NOB31_001176"
     CDS             complement(32741..33388)
                     /locus_tag="NOB31_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCI0973395.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33396..34082)
                     /locus_tag="NOB31_001177"
     CDS             complement(33396..34082)
                     /locus_tag="NOB31_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0973396.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34088..35161)
                     /locus_tag="NOB31_001178"
     CDS             complement(34088..35161)
                     /locus_tag="NOB31_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973397.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35383..36057
                     /locus_tag="NOB31_001179"
     CDS             35383..36057
                     /locus_tag="NOB31_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0973398.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36062..37402
                     /locus_tag="NOB31_001180"
     CDS             36062..37402
                     /locus_tag="NOB31_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0973399.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37551..38537)
                     /locus_tag="NOB31_001181"
     CDS             complement(37551..38537)
                     /locus_tag="NOB31_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HCI0973400.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT        11885 a         7044 c         7311 g        12377 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agttatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     9781 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     9841 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     9901 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     9961 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
    10021 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
    10081 attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta
    10141 aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa
    10201 gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa
    10261 catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa
    10321 ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt
    10381 accactagtt cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa
    10441 accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa
    10501 ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga
    10561 aaatatggat taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg
    10621 aaatagtggt ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata
    10681 ttatacaaag tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc
    10741 gtcatttttc catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt
    10801 actttttttg tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata
    10861 tgaacgaatt agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca
    10921 cagataaaca ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca
    10981 tatgtacgga tacattttcg gaccgattaa ttttaaccat tctatttatt tgcttaccta
    11041 ttagatatca ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt
    11101 ttagttcata ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt
    11161 tgatttgctg aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac
    11221 accattttcg tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc
    11281 agttaaataa gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat
    11341 acgtgcagta ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata
    11401 agcagcatta cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc
    11461 tttttctaca atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac
    11521 ttctgaatca ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa
    11581 tttcaatgcg atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac
    11641 acgtgatgtt ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt
    11701 tgaagcaaca acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg
    11761 catgattgac gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat
    11821 accagctgtg ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac
    11881 agccacattt tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc
    11941 tttttcttga ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc
    12001 ataagcgata cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt
    12061 tttcatgaat aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct
    12121 tgtttattca ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa
    12181 acgaattcct gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat
    12241 aatacaacca aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa
    12301 taagacagca atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt
    12361 cttaatgttt atttctccat tcattgggag tacatgttga atacttcttg aataatttga
    12421 ataaagaagt cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg
    12481 tttcttgaat cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg
    12541 aagcatcaaa atacattttc aatttattac taagatagac cggattgtag ccaaaatgag
    12601 ctgctgtttc ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa
    12661 gcatctcatt ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag
    12721 tcaattcgat cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg
    12781 tatcaaaata aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc
    12841 cgcgaaaatg aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag
    12901 aagaaagtag attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt
    12961 cttttaataa gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag
    13021 cttctttatc aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa
    13081 tttgtaaaca tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg
    13141 gaacttccgc atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc
    13201 ctcggtggat ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca
    13261 ttccttgttc acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat
    13321 tcagctagtt ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca
    13381 cgctgtactg ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg
    13441 gacatgaact tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga
    13501 taagcgctta caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc
    13561 tgctgtcagt ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta
    13621 tgtcagctac ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct
    13681 cttttatggt cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa
    13741 aacaaactgt gatcatcgga ttagtgattg catcgatttg tggtatcctc cccctcttct
    13801 cacaaagtta cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga
    13861 tcaattcttt ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta
    13921 tgattggttt tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag
    13981 gacagctagt acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta
    14041 ttcttgtctt gtttgttttg tttgttccta cacctgaaac aactgaactt caatcgcatg
    14101 gcacagcccc aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt
    14161 ttctcttgct ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga
    14221 cgacttattc tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg
    14281 caagtatggc tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc
    14341 ttacactttc tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc
    14401 tgtatgtgat tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt
    14461 acttattcaa ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa
    14521 tcttattggt tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct
    14581 cttttgcttc tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt
    14641 tgattagcgc gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa
    14701 gagtagatga agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta
    14761 aaatgacaaa tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc
    14821 gccatggact gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact
    14881 ggtacatgga tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac
    14941 cttccatgtt taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac
    15001 atccatgtgg aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag
    15061 gacatacatc agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg
    15121 gctggacagc aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg
    15181 atatcgcaaa agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg
    15241 aaacggagat tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag
    15301 aactaatatc tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg
    15361 tagaagctat ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga
    15421 aagctcgtaa acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc
    15481 aacttcaagt ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt
    15541 cttctttact gaatcagatc tggtcagtat cagaagaagc cttcaagtta tgtagtgatt
    15601 tgttttttat cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat
    15661 cattcatgat caatcaatat cttttttttg acgaggaaat caataaacga acgatattag
    15721 cattaagagg acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct
    15781 tgtggttgat tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca
    15841 tcgtctaccc taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag
    15901 ggtttattta tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag
    15961 aaggaacgct tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt
    16021 gcggagatat cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc
    16081 aagaaaaata tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg
    16141 gcgcttttat cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt
    16201 tcgctgtttt attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct
    16261 tattgaatga cactatcaca cagattacta ctccatattt caaattctat gaacaagatg
    16321 ctttatgcaa actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag
    16381 ggatgttatc tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa
    16441 atgaaaagta cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag
    16501 caagcccaat ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt
    16561 atgaagaatt tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac
    16621 ctatcaaaga tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg
    16681 atagaacagg cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc
    16741 cacttgtctt aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat
    16801 atcagaagac tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc
    16861 ttaattctgt tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa
    16921 tacgacaagt aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc
    16981 tagtttccca agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc
    17041 gattttaaga tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct
    17101 attgaaagca gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc
    17161 agaagcagct ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa
    17221 gcctatcata gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa
    17281 tacagcatta ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg
    17341 tacgagtttt ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac
    17401 cccttgaagg acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat
    17461 tacagcgttg tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc
    17521 aagtgcgaca tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa
    17581 gctgaaactt ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt
    17641 tccgatccat ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt
    17701 gtttccagtg atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt
    17761 tccttcgaag accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac
    17821 taaaatgact gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa
    17881 tttatatctt gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa
    17941 agcagtaggt gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac
    18001 tactccttga gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact
    18061 gattaaacca gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg
    18121 gatcacttct gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac
    18181 gaggatggag ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag
    18241 ttcctccctt gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt
    18301 cttcgctgtc aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg
    18361 tatctttcaa agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa
    18421 catccgtatg acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt
    18481 tgatgttcat ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt
    18541 tcatatcatt cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt
    18601 aataaatctt gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga
    18661 agatgtgcct cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga
    18721 ttatcaagca gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg
    18781 ccatcttctg gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca
    18841 tactgctcca cgcgctcgat catagctttg atataacttt cttctatttt attttctgat
    18901 aatagcggct gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat
    18961 tggatcattt cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct
    19021 aaaagtttgt tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct
    19081 tttaattcga tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat
    19141 cctggtatca gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc
    19201 atgattggat gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta
    19261 gaaaaaataa tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc
    19321 tctgtaaaaa agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag
    19381 ctaatgccac ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc
    19441 gcttttctga tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg
    19501 ctcttcccta ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa
    19561 gcatattgat gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata
    19621 cgaaaatagg cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca
    19681 aattctacgg ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa
    19741 aaatcaagtg caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa
    19801 aatataatct ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta
    19861 atgtcagtga ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt
    19921 tttccaattc gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt
    19981 gcgaatcgaa gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa
    20041 taatcaatgg aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc
    20101 atcaaacgag cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc
    20161 ctaaaaccag ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt
    20221 atctttttga tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga
    20281 aaaacagaaa cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct
    20341 tgttcggtat acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt
    20401 gctcggaatt tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat
    20461 tgtttgatcg cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt
    20521 tctcttggtg ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac
    20581 ttatattcta gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg
    20641 atttttttta cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg
    20701 accaaatgtc tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt
    20761 ttttgaggtc agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt
    20821 ttcaaagtga ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa
    20881 agctgtttct ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc
    20941 ttctgtttca ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat
    21001 tgaacctctt aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag
    21061 tagttctata ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat
    21121 tcttacaaat atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca
    21181 aaattttcat ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta
    21241 atgtctcgta aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt
    21301 cttcatgata actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat
    21361 cgataccaaa gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat
    21421 cttttgtttg tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt
    21481 tgatgcggaa ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat
    21541 cgaagtaatc attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat
    21601 ctggttcgcc gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat
    21661 agctgttcgc agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat
    21721 aatgcatttc tacttctaaa atatccccta attttccgct ttcgattact ttttggactg
    21781 tcaagaagtc agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt
    21841 ttgctaatgc aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta
    21901 gtacattctt accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg
    21961 tagtgatgac aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat
    22021 attcgatgtc ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat
    22081 tgattttgtt cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat
    22141 tgccaagata agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata
    22201 tcctagaaaa gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac
    22261 acttgttatc attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga
    22321 tagtagcgga accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt
    22381 gaagaaaaac taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac
    22441 atccgtagga atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg
    22501 tatacttccc attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa
    22561 gaattccgtt tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg
    22621 attgatccta attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg
    22681 gcggatttat cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta
    22741 gatcaaatcg gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat
    22801 tctcaaatca cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc
    22861 atggctgaag aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc
    22921 gccattttta ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg
    22981 aagcatgtag aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa
    23041 caggctgata tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact
    23101 ttctcctctc aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct
    23161 caaaattttg aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc
    23221 cttcttaaag aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag
    23281 tgtttgatag gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac
    23341 ctcagcctgt ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct
    23401 aacttctgtt tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca
    23461 gtatacatgc agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta
    23521 cttctttttg aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat
    23581 gactgttgac catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga
    23641 ttctcagatc ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga
    23701 gtgtccgtcc attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg
    23761 tgaacaactt tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc
    23821 cccccgtagg ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat
    23881 tcgtttcatc aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg
    23941 tatgtttctc aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat
    24001 ctgcacctgg atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt
    24061 ggattttagc catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga
    24121 tctgctgatc cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta
    24181 ttcctgagag aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca
    24241 tttgtgttct ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc
    24301 cgctgctcct ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca
    24361 aagtacagtc cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc
    24421 ttaccgcctg ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc
    24481 aactgtcctg ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat
    24541 ggaacatatt tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct
    24601 gtcacatcga ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat
    24661 acccagctga cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct
    24721 tgatcacgaa cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct
    24781 actttaacaa atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt
    24841 gtatgcccgt tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg
    24901 ttcaaatgca tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa
    24961 ttcggatcaa ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg
    25021 tcgatttctt tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca
    25081 aatgttaaag cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt
    25141 ccttctttat cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca
    25201 ccgattgcga catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca
    25261 tttttgatgg tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt
    25321 gtttgctttt caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt
    25381 ccaacttcta aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca
    25441 ttgttgccga tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt
    25501 gtccaagtgt acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct
    25561 tcttctttag aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt
    25621 tttgtaactt tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta
    25681 tctagttctt ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca
    25741 gggaaagcta aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc
    25801 gtgtagactg catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca
    25861 gcatctgtcg ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt
    25921 gctgcatcca cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa
    25981 actgaaaatg aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg
    26041 ctgttttgga ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga
    26101 gctgctgtct cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa
    26161 ataaggaaaa ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc
    26221 ctgttctttt tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc
    26281 ctaaaagtgt atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt
    26341 tattgactac tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg
    26401 taaacggaat ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc
    26461 gataacttcc tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt
    26521 gaagcgcatc tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat
    26581 ttcctgcttt gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg
    26641 tctcgatttt gacaaattgc ttactccctg tatatacaga gactttcttt gtactgacac
    26701 caaaaccaaa atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc
    26761 ttagctgcat ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga
    26821 tcgaaaataa aacatcaaat ccgtgaggtt tcttgtgtat gacaaagcct tctgtcagct
    26881 tttctccatt cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac
    26941 tatctgacaa ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg
    27001 aataagtgat tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa
    27061 aaggtggatc agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt
    27121 tttgattgtt ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga
    27181 cgacttctgg tactttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt
    27241 tagcggccag agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt
    27301 ctgcggtaaa cataccggaa gacgcaccgt tttttgcgat ctctgcttgt gcttcttcta
    27361 ccgttttgcc cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg
    27421 tgacaccatt taatcctcga tacgtttgta ataaagcttt ttcttgtccg tcatttggat
    27481 gatttttcgg cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt
    27541 ctgtttctgt ttctgttgct acctgagtaa aagctggttt aaatagtaac aagaagagac
    27601 acatactaag ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa
    27661 aagataccaa atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc
    27721 aattcctccc gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg
    27781 gttgtttttg gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga
    27841 cccatcttcg tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt
    27901 aaaagtttcg gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt
    27961 ttcttgtcca tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc
    28021 tccttttaat gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag
    28081 tcgattttga tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta
    28141 aatgattttt ctatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc
    28201 ggcaggacca gctgtttcaa cgactcgata tttaccaggt gtgagtgaat caaaactggc
    28261 aagacctttt tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt
    28321 tttctgtagg gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc
    28381 atacttacgt actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt
    28441 atcatcggaa gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt
    28501 gatttcccaa gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag
    28561 cgtataggtc atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc
    28621 atgatctgtt agtaaagtat caatagaatc tcctgttaat ttgaaaacag cgccaataag
    28681 atccttttca cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt
    28741 agtatttttc catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc
    28801 tttgattgtt tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat
    28861 ctcttgataa ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacgt
    28921 atttgttgta tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc
    28981 atttgtcgta tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt
    29041 gttgtcaaat tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga
    29101 tggtataccg aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc
    29161 gttcatttga taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg
    29221 gtaatggatt tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt
    29281 tccttctatg gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga
    29341 aagtgtacca ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct
    29401 tacagttgct gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg
    29461 atcagctgat tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg
    29521 agactctact tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag
    29581 accatgtatt tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa
    29641 cgtactgtcg attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat
    29701 tagagaagta tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct
    29761 gcttgattgt gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag
    29821 caaaacgatc acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag
    29881 tgctttttgt gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt
    29941 tttcactgaa tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct
    30001 tgagtagccg acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc
    30061 gacaaaacga tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc
    30121 tgaccagtct acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg
    30181 agcattcaaa taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat
    30241 cgcatagtct gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt
    30301 aggatctcca ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg
    30361 atgatcaaga acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg
    30421 atcatctgtt gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa
    30481 ggataatgta ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc
    30541 ttctatttcg tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc
    30601 aataatgtca tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc
    30661 tggatcgatt ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt
    30721 aattttcccg ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact
    30781 taagtaattt tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc
    30841 atttagcttg atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat
    30901 tgtttctaaa actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt
    30961 tgataaactc aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat
    31021 ttttcccctc ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa
    31081 acaggcgtta cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa
    31141 gggaatcaca ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta
    31201 atgagcgttt cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga
    31261 attaaactat agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat
    31321 gactaaaaaa gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat
    31381 cgaagagatc aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg
    31441 gtatcgtctt gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca
    31501 aagttctaca aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga
    31561 gtattattgt gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg
    31621 caatcaaatt ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac
    31681 tagccttaaa agtgagctcc agttgcgtat ctttgttacc tttttctttt taagttacta
    31741 cggaagacgc acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa
    31801 gaataattgt cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat
    31861 tatgtatttt gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc
    31921 tggagactct tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa
    31981 tctcttagga aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac
    32041 gattttttca gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa
    32101 tatgtcctac tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt
    32161 tcaattatta acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt
    32221 gacgatccgt gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc
    32281 tggatttcgt gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta
    32341 tttatctagc tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc
    32401 tgataaaaaa atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga
    32461 atatatcagt gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga
    32521 agatcagctg tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat
    32581 tttgaatgcc catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga
    32641 agaactcatc cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc
    32701 tgataaaaat ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa
    32761 tccaacgaga tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa
    32821 tgagatccgt caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt
    32881 cttccgacga ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca
    32941 ttggagaatc agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta
    33001 acaagtataa cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat
    33061 atttttcgat ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt
    33121 gatggactat gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa
    33181 aatatttata aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga
    33241 cttggctgat gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct
    33301 ttgcgttcga taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga
    33361 ttatacgtgg atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct
    33421 gtcaagtacc catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca
    33481 tgagtaacca taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg
    33541 acttcatatg catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt
    33601 ggctcattat ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct
    33661 ttaggataac tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt
    33721 gttgaatctt ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt
    33781 aaaaaaggaa tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct
    33841 gctcgttttt tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa
    33901 gtcggtgttt gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga
    33961 ccaatgatgc tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag
    34021 acctttgtat gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc
    34081 atttttatta acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa
    34141 acaatccgcc tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc
    34201 aaaaaacagc aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa
    34261 gagcaagcag aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga
    34321 tgaagaaatt tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg
    34381 tcatcacgta catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca
    34441 tcgcatttaa ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa
    34501 tagttaataa ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta
    34561 ttacgatccc attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca
    34621 aagcagtcca cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag
    34681 gaaagatacc gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa
    34741 ttttatagcc tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt
    34801 catgcccttt cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa
    34861 cattttcttt gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc
    34921 ctccttcaat gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg
    34981 catcctccga caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt
    35041 ctgaaagtcc attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa
    35101 taccgacgat caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca
    35161 tttgtttttc ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta
    35221 actctaaagt gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga
    35281 catctttcga taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct
    35341 ttccatgata aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta
    35401 gtagaagacg ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag
    35461 ataacacaag tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat
    35521 cttgcaatct tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata
    35581 cggaaagaaa aaatacagac tccagtattg attttgactg caaaagatag tttggaagat
    35641 aagattgaag gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa
    35701 gaactgatca tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat
    35761 gttctgaagt ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa
    35821 caagttttgc ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag
    35881 ggaatcattt tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg
    35941 acgattacag ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga
    36001 ttggataaag aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc
    36061 aatgaatgga gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc
    36121 atttgctttt atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc
    36181 atacagagaa acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt
    36241 agagatacaa agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa
    36301 cagaacaaac atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt
    36361 gatcttgtgg tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa
    36421 ccaaatcaaa gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt
    36481 aaatgaagac agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac
    36541 gaatcaagat ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc
    36601 attagcgact tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat
    36661 tggtatcagt tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag
    36721 acaaaaagaa tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca
    36781 aaatagtttg gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag
    36841 catcgctcaa gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac
    36901 aatcgctcgg aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga
    36961 atatatcgaa caacttgtta aaccatttca agagatggcc atcatagatg gaaaagagtt
    37021 tattctccat aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt
    37081 tttggttatt ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt
    37141 ggattcatct gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat
    37201 cagtgaagaa gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc
    37261 gaaagagact ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca
    37321 tcatggacag atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt
    37381 gccgttgaag cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt
    37441 cacagccctt ttttgttgcg aataaacggt gttccagaag tagcttcttc ggaaataagc
    37501 cgaaatttct ttaagctgac cacttctgtc acaacctctt tagcttacgc ttacgatttt
    37561 ttattgcggt cttcaatgtg tacatcaccg cttgtgtcaa tatccaattc ttctcggcta
    37621 acatcttctg tcactttttc aacatcttca tgttcttctt tatgaatccc aacttcttca
    37681 cgaataactg tatgtttgct tacatctact tgctcttctt tgattgggat agtaatcgtg
    37741 tcatcttcca atttttcgtc tgttccctgt gaagattgat ctgttactgg tttgcgttcg
    37801 atgacgattt cttcacgttt gaccggtact tctaccgttt cagtatcgtt gaccacatgt
    37861 ttgtggatgt cgacttctcc agttgtcaca tcatgtgtat ttacatctaa tttttcttct
    37921 tttagttgaa ttgtatcatc atctagattt ggtttgcgat cgatgtcttc agtcttgctt
    37981 gtacccattg tatcagtctc gccaggtacg tccatcggat cagttcctgg tgtcatattc
    38041 aatggatccg ttgtattttg aaagcctgtc gtgccaccta cgtccattgg atctgttcca
    38101 gtgccagttt ctaatccagt ccccattgtg cttgctgggc taacagtatc ttgtgtatcc
    38161 attgtatctt ctgttgtttc tggctgacga tagcctttta ctgtgatgac aaattttcca
    38221 tcagaaatat ctcctctata ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa
    38281 tcataggtat caaaagaaaa agtatctttt attttttccc ataaagaacg gtcttcttca
    38341 ccatccatcc gattttcatc tgtttcaaca tctataccag acaatccgtc aaatcctagt
    38401 ctagatgctg cttcatcagt agtataaata acgatatcat ctcgttcata cccttcgtta
    38461 cgcaaccgtt caattactga taatgcttct tccctcgtac tatagcttcc gatgaccgtt
    38521 aaatttttct cttccatgta aattcctcct agcaaataga tttatgattg gtatattgtt
    38581 acttataaat ttattctata ggagacgatt gttttct
//
LOCUS       DAIGSZ010000022        37384 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.022, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000022 DAIGSZ010000000
VERSION     DAIGSZ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.022"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..614
                     /locus_tag="NOB31_001182"
     CDS             <1..614
                     /locus_tag="NOB31_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCI0973401.1"
                     /translation="VFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVGK
                     YMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGTG
                     VFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPFI
                     LALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            611..1384
                     /locus_tag="NOB31_001183"
     CDS             611..1384
                     /locus_tag="NOB31_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCI0973402.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1381..1779
                     /locus_tag="NOB31_001184"
     CDS             1381..1779
                     /locus_tag="NOB31_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HCI0973403.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1964..2635
                     /locus_tag="NOB31_001185"
     CDS             1964..2635
                     /locus_tag="NOB31_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973404.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2694..3134
                     /locus_tag="NOB31_001186"
     CDS             2694..3134
                     /locus_tag="NOB31_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973405.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3146..3814
                     /locus_tag="NOB31_001187"
     CDS             3146..3814
                     /locus_tag="NOB31_001187"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCI0973406.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3878..4501
                     /locus_tag="NOB31_001188"
     CDS             3878..4501
                     /locus_tag="NOB31_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HCI0973407.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4557..4943
                     /locus_tag="NOB31_001189"
     CDS             4557..4943
                     /locus_tag="NOB31_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HCI0973408.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5156..6547
                     /locus_tag="NOB31_001190"
     CDS             5156..6547
                     /locus_tag="NOB31_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HCI0973409.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            7158..7526
                     /locus_tag="NOB31_001191"
     CDS             7158..7526
                     /locus_tag="NOB31_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HCI0973410.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            7706..8647
                     /locus_tag="NOB31_001192"
     CDS             7706..8647
                     /locus_tag="NOB31_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HCI0973411.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            8716..9447
                     /locus_tag="NOB31_001193"
     CDS             8716..9447
                     /locus_tag="NOB31_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HCI0973412.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            9591..11771
                     /locus_tag="NOB31_001194"
     CDS             9591..11771
                     /locus_tag="NOB31_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HCI0973413.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            11791..12273
                     /locus_tag="NOB31_001195"
     CDS             11791..12273
                     /locus_tag="NOB31_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HCI0973414.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            12289..13050
                     /locus_tag="NOB31_001196"
     CDS             12289..13050
                     /locus_tag="NOB31_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCI0973415.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            13181..14515
                     /locus_tag="NOB31_001197"
     CDS             13181..14515
                     /locus_tag="NOB31_001197"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HCI0973416.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            14822..15307
                     /locus_tag="NOB31_001198"
     CDS             14822..15307
                     /locus_tag="NOB31_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HCI0973417.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            15300..15983
                     /locus_tag="NOB31_001199"
     CDS             15300..15983
                     /locus_tag="NOB31_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HCI0973418.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            16109..18754
                     /gene="polA"
                     /locus_tag="NOB31_001200"
     CDS             16109..18754
                     /gene="polA"
                     /locus_tag="NOB31_001200"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HCI0973419.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            18799..19635
                     /gene="mutM"
                     /locus_tag="NOB31_001201"
     CDS             18799..19635
                     /gene="mutM"
                     /locus_tag="NOB31_001201"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HCI0973420.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            19599..20228
                     /locus_tag="NOB31_001202"
     CDS             19599..20228
                     /locus_tag="NOB31_001202"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HCI0973421.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            20280..20612
                     /locus_tag="NOB31_001203"
     CDS             20280..20612
                     /locus_tag="NOB31_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCI0973422.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            20924..21415
                     /gene="nrdR"
                     /locus_tag="NOB31_001204"
     CDS             20924..21415
                     /gene="nrdR"
                     /locus_tag="NOB31_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HCI0973423.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            21438..22811
                     /locus_tag="NOB31_001205"
     CDS             21438..22811
                     /locus_tag="NOB31_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCI0973424.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            22811..23737
                     /gene="dnaI"
                     /locus_tag="NOB31_001206"
     CDS             22811..23737
                     /gene="dnaI"
                     /locus_tag="NOB31_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HCI0973425.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            23866..24306
                     /locus_tag="NOB31_001207"
     CDS             23866..24306
                     /locus_tag="NOB31_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCI0973426.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            24450..25151
                     /locus_tag="NOB31_001208"
     CDS             24450..25151
                     /locus_tag="NOB31_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HCI0973427.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            25148..26269
                     /locus_tag="NOB31_001209"
     CDS             25148..26269
                     /locus_tag="NOB31_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HCI0973428.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            26284..27516
                     /gene="pepT"
                     /locus_tag="NOB31_001210"
     CDS             26284..27516
                     /gene="pepT"
                     /locus_tag="NOB31_001210"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HCI0973429.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            27648..28556
                     /locus_tag="NOB31_001211"
     CDS             27648..28556
                     /locus_tag="NOB31_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HCI0973430.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            28591..28863
                     /locus_tag="NOB31_001212"
     CDS             28591..28863
                     /locus_tag="NOB31_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HCI0973431.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            28874..29920
                     /locus_tag="NOB31_001213"
     CDS             28874..29920
                     /locus_tag="NOB31_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HCI0973432.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            30171..32780
                     /gene="clpB"
                     /locus_tag="NOB31_001214"
     CDS             30171..32780
                     /gene="clpB"
                     /locus_tag="NOB31_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HCI0973433.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(32931..33617)
                     /locus_tag="NOB31_001215"
     CDS             complement(32931..33617)
                     /locus_tag="NOB31_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973434.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(33595..34089)
                     /locus_tag="NOB31_001216"
     CDS             complement(33595..34089)
                     /locus_tag="NOB31_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCI0973435.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(34109..35329)
                     /locus_tag="NOB31_001217"
     CDS             complement(34109..35329)
                     /locus_tag="NOB31_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0973436.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            35476..37311
                     /gene="lepA"
                     /locus_tag="NOB31_001218"
     CDS             35476..37311
                     /gene="lepA"
                     /locus_tag="NOB31_001218"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HCI0973437.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
BASE COUNT        12417 a         6550 c         8100 g        10317 t
ORIGIN      
        1 ttgtttttgc accgttagaa ggagaagacc tcgcttcatt tctggttggt gcggcaatca
       61 tgatgatcgg aatgacgctc tttttgtttg gagcagatta ttctatgatg gaagtcggag
      121 atctagtagg gaaatatatg atcaaaaaga aaagtttgac cgttttggtc agtttgggat
      181 ttgctatcgg gatcgtgatc acgattgctg aaccttccgt gcaagttttg ggacaacaag
      241 tatatgatat atctgacgga gagattggca gagtgttgct gattgggatc gtcagcgtcg
      301 gcactggagt atttctagcc tttgcgctgc ttcgggtcgt attcaagcta tcctattatc
      361 aattgatggc tataggctac ataggcgttt tgatcgcctc atttttcacc agttccgaat
      421 ttatgccgat tgcttttgat tcggggggag tgactactgg tccagtaact gttccattta
      481 tcttggccct tgccggaggg atgactagta tgatcaaaca aaagaaaaat gaaaatgaca
      541 gttttggaat ggtcggtatt gcttcgttag ggccgattct tgccgtgatg attttggggg
      601 tgatcttcca atgagtttct ggcagcaagt gatagatgga atcgaaatcg ttaccatgga
      661 agtcattttg gcagtggcac ctatcgtaat cctatttgtt ttaatgaata tcattagttt
      721 tcgtatgcgc aaaaagcgtt tctttgacat tatgaaaggt ttcttgataa cgactattgg
      781 gttgatcctt ttcctgcacg gagtcaatat ggcttatgta ccggtaggac agcatttagg
      841 cagtgctatt gcgggattgc cttacaatta tatactggtt ccccttggct ttttaatggg
      901 gttcttagta gggtttgctg agccggcgat tcatgtaatg atcaaacagg ttgaagaatt
      961 gagcgagggg agaatccgat cgaaaatcat gctgatggta atttcaattg ggatcggcgc
     1021 agcagtagga ttgtctatgt ggcgtttgct cgtcggattc tctctttatt atttcttgat
     1081 cccaggatac gggctagcat ttattttagg acgaaaagtg gacaagatct ttttagcaat
     1141 ggcttttgat aacggtggag tagcaacggg cccgatgtgt tcgacattta ttttatcaat
     1201 gagcgtggca atcgctgcac aaattgaagg aagagatccg atcattgacg ggtttggtgt
     1261 ggttgcaatg attgcattga caccaatatt atccacttta gtactaggat atatttataa
     1321 acgaaaagat gaaaaagaca gaatcgaaaa agaaagattg caaaaattgg gggaaagcaa
     1381 atgaaagatc ttgtagcatt gaatcttcac atgattgtga cgatcgttga cggaggaatg
     1441 ggcgaagatg ttatcgactt ttcaaaagaa gcaggtgcag caggcggaac gatcttacat
     1501 ggaagaggtt ctggtgtaca tgattcaggg aaatttttag gtttggacat ttcgccagaa
     1561 aaagatattg tgttgacatt agtacccgat agtttgacga ataaagtaat ggatgcgatt
     1621 ggtcaaggca tcaacatcga tattccaggt aatggtattt gttttagtat tgatgtagac
     1681 aaagtcattg gtatcactaa gattcatcaa tatcgagaaa ttatcggaat gcaagaactt
     1741 ttagatgaaa ataacgatag agaaaagtct gaatcataga caagcgtttg aagaggaaat
     1801 aaacacaaac aagaaggcgg atgagcgtta tttccgcttt tttgtttgta tttttctcgt
     1861 gaatacttat gaaatagtaa atttttatga aattctactc taagcatcag actttctttt
     1921 caaaatatgc tattttaaaa atgatgaaaa aagggggaga aaaatgaatt ttttagttgt
     1981 tttaaaagat actctgattg agcgatttac atttctatat gttcaattgc aggaaaataa
     2041 aacattgctg catttttcac cagagttcca tctagagggg ctaacattag gagaaatcta
     2101 tcaagcagaa gggctgtcgg ctgttttgca cttttttaag gtagaattgg aattaccagt
     2161 aaaagattat atcgagcttt ctcttgaatc ttgggatcga gcagtggttg aactgtttcc
     2221 agaaggttta atgatcgata caaacgatgg gaagatccat ctgactgcag cagaactgca
     2281 aaaacaaatg cgttatcaaa tagatgacga aaattctttt tctattttta gacgtcagca
     2341 aaagattcta aaaagctttt taaaagtgat cagtaaaaaa cggaatctga tcaaaacgac
     2401 acagctgttg aaaaaatatc caggtctgct tcacacgtct attcaatttc ctcaattgat
     2461 tacgatgatc catcgtttta tacgtatgca acagctacca tctaagaagc tgtttcttcc
     2521 attgacggac acatttcgag tagtcaacag agaagataaa aagaaagtga ttgtgattga
     2581 ctttaccaga aatcggaatg tccttcacca agttgcaatg gaaaaggcca attaaggctt
     2641 tttctttttg gatttttttg tcataataaa tattagatga tggaggagat aatatgatgc
     2701 aaacatggtt agaaaggcta atacgatttc agcagaacta tcacaaactt atgcagggaa
     2761 gatatgcgaa atttgatcag ttgaatcgcg gtctattgat cgctgcgctt gtctttagtt
     2821 tgctaagtcg ttggttgccc tatagaatcg gacaattgtt gttcatcgtc tttttcggat
     2881 ggatgatatt tcgtttccta tcaaaaaaaa tctaccccag actaaatgag aatcaacgtt
     2941 atttgaaata tcttgataga gtcaaagaaa aatatcatca gataaaaaac aaaaagcaag
     3001 tcaaaatgga tcgaaaaagt tatacttttt ttgagtgccc gaattgtcat caaaagcagc
     3061 gtgcacctaa aggaaaagga cgaatacgtg tgacatgcaa aacatgtggt ataaaattcg
     3121 aaacgaatgt ttaagggaga aaagaatgaa attagtatta ttacgtcatg gcgaaagcga
     3181 agcaaatttt gaaaattact ggacaggatg gctagatgtc gccttaacag aaaaaggaaa
     3241 agaacaagca gcagttgccg gtcaaaaaat gcttgaagcc ggacttcaat tcgatgccgt
     3301 ttatacctct gttttgaaac gtgcgattct taccggacaa gtcgcactag aagaaatggg
     3361 tcagttatgg cttcctataa taaaaacatg gcgtctaaat gaacggcatt atggggatct
     3421 tgtgggtaaa aacaaagata agatgaaaga aatatacgga aaagatcaag taaaaacatg
     3481 gcgcagagga tatacggaag ttccgccgtt aaccgcagaa aatagatttg accgcagata
     3541 tgatcacttg gatccgcatt tgatcccata cggagaaagt ctggaaatga cagtgaatcg
     3601 gatcattccc ttatggcaag atcatctagc accaaaacta aaagatcggc aagatttact
     3661 agttgtgggt catggtaata gcatccgagc actgacaaaa tatttagaag atgttcctga
     3721 agatcaaatg gatacgatcg atatcccaaa tgcacaacca atccagtata cattagcaga
     3781 tgatttgaca attctggaca aaaaaatact ttaaagaaca cctttatcta aaagtgagag
     3841 atagaaaaaa gaagcaaagg aatggaacaa aaggaacatg aaaaattata tatgggactt
     3901 tgatggtaca ttgtttgata cgtatcccgc aatggtagat ggtgcatggc aagcactaaa
     3961 agattttggt atcagtatgg acaaaaaaga aatctacttc aaaatgaaaa agtattctac
     4021 tagttatttg atcaatgaat caaacttgaa tgccagagag tttaatgaat tatttcaccg
     4081 atatgaaaaa gaaagtacgg aagtttcccg tccatttcca gaaacgaaac aagtactgga
     4141 aatgctaaaa gacaacggcg gtcgtcattt catcctgacc caccgtttga cagaatcaac
     4201 atggggcctg ttaaaagaac atcgattggc acatctgatt gaggaagtag tagggatcga
     4261 tcaggacttt cctcgtaaac ctgatccagc atctttaaat tatttgatcg atacttttca
     4321 tttagaaaga acagacacga tgatgatcgg cgatcgtcgt ttagatatcg aagcagggaa
     4381 aaatgcagga gtcgctactt gtctttacga catcgatcat tttctgggtg agatcccggc
     4441 agattatgtg gtaggaaatc tgaatgaaat ccttaccttg cagagcatca ttaaaaagta
     4501 gtatcccctt tcaaaggaga tatgttataa ttttcataaa ggagtgataa aattatatgg
     4561 aaatcagaag acaaaaagaa gttgtagaag catttcatta tgatatgaga ttgccgaacc
     4621 aagaagtaga aacagatttg aaagtaggct tctcgccttt aaaagaaacg atcgaaaact
     4681 atccgaaaga acatagcatc gtaggagcac gcttagagtt ccgtttagtg tttgatacat
     4741 atgttttatc tggaagtgtg agtcagatca atcatatcct caatcggaaa attgaaggtc
     4801 aaaatgatgt cacacaagaa gaagtggacg agctagtagc accgttattc gatatcgtac
     4861 gccgaatgtc ttatgaggtg acagagatcg ccttagatca gcctggggta aaattgaatt
     4921 ttcaatcaga aaaacaagaa tagacagtaa aaacatacct gcgatagatt aaagctatca
     4981 caggtatgtt tttttattac taattgtaag caaaaagaat gtcatttcga taaaaatcgt
     5041 ctaaaatata aaagtcactg aaaaaaattt tttcaggagg atggttgaag aatcattctc
     5101 gggaaccttt acttccttcg atggacttgt cattaataat atgaggagga gaaaaatgac
     5161 aacactcatc acagttttag tggttctagt ttttgcggca ttattatatg tgttctatcg
     5221 tatgcaaaag cgccatacaa aattttcaac acgcgtcttt acagcattag gagttggtat
     5281 cgtctttggc ggtctgcttc aattgatctt tggtgtagac gacaaagtcg ttactcaatc
     5341 aatggaatgg atcgggattg taggtcaagg atatgtatca ttcttgcaaa tgctagttat
     5401 gcctttagtg tttatttcga tcattggtgc attcacaaaa atgaaagttt ctgaaaagct
     5461 agggaaaatt agtgcgactg tattgacttc tttacttgga acaacagcta ttgcagcatt
     5521 gatcggaatt ggttcaacaa tgctgttcgg actccaagga gctaaattca cacaaggagc
     5581 tgcagaaaca gcacgaatct ctgaactggc aacacgtcag gaaacagttg aaaacttatc
     5641 gattccacag cagattttat cctttatccc taaaaacgtt tttgctgatt tagcaggtag
     5701 tcgtgcaaca agtacgattg gagtcgttat tttcgcggca tttgtcggaa tcgcttatct
     5761 aggcgtgaaa agaaaagcgc caaaagaagc agcattcttt tcagatttag tcgacagtct
     5821 gtataaaatc attatgcgga tcgtgacgct tgttttgcgt ttgacacctt atggagtatt
     5881 tgctttgatg acaaacgttt tggcaacaag tgattttgca gctatcgtca atttaggtaa
     5941 atttgtcgtt gcttcttacg tagcattgct tgctgttttg attgtccact cactgatttt
     6001 gattggtgca aaagtcaatc caatcaacta tttcaaaaaa gcctttccgg tattgagctt
     6061 tgcgtttact tcacgttcaa gtgctggagc tttgccattg aatatcgaga ctcagacaaa
     6121 agctttagga gtagatgatg caacagctaa tttctcagca agttttggtt tgtctattgg
     6181 acaaaacggc tgtgctggcg tttatccagc tatgttggca acgatcgtcg caccagcagc
     6241 tggagtgaat gtctttagtt tggaatttat tttgatgctt gtggcaattg taacaatcag
     6301 ttcttttggt gtagctggag tcggtggggg cgcaacattt gcttcactga tcgttttagg
     6361 ggcaatgaac ttgccagtag caatcgttgg gttagttatc tctgttgaac cattaatcga
     6421 tatggcacgt acagcagtaa acgtcagcgg tagcatggta gctggtatcg tgacaagtgc
     6481 acgcatcaaa gatttagatc gcgatgtcat caatgatgat tctaaagtga tcgatgtgaa
     6541 tgcatagtca aaaagaggtt gtgatagaag tggtcagctt taagaaataa gaagaagttt
     6601 cctaaaaata gtttctcaaa tttttgtgaa atttcggctt atttccgaga agctacttct
     6661 gaaacaccgt gaataagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
     6721 aaacaaaaat agttcctcat attttacgtt tggttgagct tattaccgca gatgcaagct
     6781 tttgaacacc gtttaagaaa gaggtcgtga gcctgccgtt tcactctgag tcacaaagag
     6841 caatttcaaa aaatagcttc tcatgtttgt tgaatattgt gtcttgtgac cgaggagttg
     6901 tcaggagaac accgtttacc agaggttgtg acttgttttt agtcacgacc tcttttttta
     6961 tttattccat ataaatacac attatttatt ccgaaaagtg aaagcgcaaa taacaaaaac
     7021 aaccaactta tttattatta aagaaaagcg tatttaagta ggacgattct gttgagagct
     7081 ttcgtagatt ttcccatttt cctatggtaa actgacaaag ttgagaatgt tagaacagat
     7141 cgtttaggag gaaacagatg tttacgaatg aaataaaaat catgctttat gtggacgatg
     7201 tagaaaaaaa tgcaacgttt tggagagcag ttggctttgc ggaaaaagat cgtcaagaaa
     7261 tggatgggac gcttataatt gaagtaggag ttgaggacag tcaaacctca tttctgttat
     7321 atgatcgagc atttgttgag tcccattcac ctggcacagc tactagtgcc ccatctttga
     7381 tgttttacag taaagatatc tttggactat ataaaaaaat gcagacgcaa tcagtcacat
     7441 taggtgatat ggtacagctt ggagaagaat atgtctttaa ctttgctgat cccgatggca
     7501 actactttgc ggttacaggt aaataataga aataaagact ttgtttttct gtgcgaaaca
     7561 ggaaagcgaa gtctttttaa ttcaaataat aatattatgt aaacaaaaaa ctttccatgc
     7621 gtaattatac acaagcaaat aaatcgtcaa atgcgaacgc cttctttata ctgtttagga
     7681 acgaaaagaa ggaaggaaga aatacatgga ttatcaagta ctgctttatt acaattatac
     7741 aaaaatcgaa gaaccagagg aatttgccaa aaatcattta gccttttgca aatctttgga
     7801 tcttaaaggt cgtattctag tagctgaaga aggaataaat ggtactgtgt ctggaaccgt
     7861 tgaaaacacg actgcctata tgaaagcaat gaaagctgat cctcgatttg ctgatacgat
     7921 gttcaagatc gatccaagcg aaggacatgc ctttaagaag atgtttgtaa gataccgtcc
     7981 agagcttgta agtttaaagc tagaagagga cattgatcca aaccaagtga caggtgccta
     8041 tctttcaccg caagaattta aagaagctat tttagatgaa cagacagtgg tgattgatgc
     8101 acggaatgat tatgaatatg acttgggaca ttttcgaggg gctgtacgcc cagatatacg
     8161 cagttttcga gagcttccag actggatccg cgagcacaaa gaagaattta tggaaaaacg
     8221 ggtagtgacc tactgtactg gtggcattcg ttgcgagaag ttttctggtt ggcttgtccg
     8281 tgaaggattc aaagatgtcg gacagctgca tggcggtatt gctacttatg gtaaggatcc
     8341 tgaagtccaa ggagaattat gggacggcaa gatgtatgtg tttgatgaac ggatcgctgt
     8401 cgatatcaac caagtagata aacaaatcgt cggtcgcgac tggtttgacg gaacaccatg
     8461 tgaacgatat atcaattgta gcaatcctga gtgcaatcgt cagattcttg cttccattga
     8521 aaatgaagaa aaacatttag gagcatgtag catagagtgt gcgaaacatc cgcgcaatcg
     8581 ctatgttcaa gaccatggaa tctctccaga agaagcagaa ctgcggttta cagctttaat
     8641 taaatagaaa acaatagttt tgattgtcga ccatttccaa tatgcgctat actagcgttg
     8701 aggatggtga tccacatgaa atcattgatt tatgctattg gggatgtcca tggcaaacat
     8761 gagctttttg aaaaacttat tcactattat gatccaaaga tccatcagct tgttttatta
     8821 ggggatctca atgatcgagg tcctcgtaca aaagaatgtt ttttattagg aaagcaatta
     8881 gtcgaagaaa caggagccat ttacctccgg ggaaaccatg aagaatattt tttgcaattt
     8941 ctgcaatcac cggaggactg gtatgcgcct tatatgagaa atggtggaaa agaaacgttt
     9001 gaaagcctga ttcacccagg ggcatcggag gaatactccc caactgaaat ctcgatgatg
     9061 atccaatcga gatattcaga actgattaaa tttttagtcc agcgcccctt gtattatgaa
     9121 tgggaaaatt atctttttgt ccatgccggt gtggatttga caaagaaaga ctggcgtaag
     9181 acaagtctaa gagactttat ttggataagg gaaccatttc atgaagggaa aaacaataca
     9241 ggtaagacaa ttgtatttgg acatacgatt acaccaatgc tccatggaga tatgcagaca
     9301 acagacctct ggattcagga tcataaaatc ggaatggacg gtggggctgt attcggaggg
     9361 tcattgcatg gggttgtttt tgacaaggaa ggtattcttc aagatattga atatcagaac
     9421 aacgaaggac cttggcatgg aatctgacta atggaaagaa tgaaggagct gtgactttgt
     9481 tgcggctctt tttattttta tagagaatat tgtttctttc agtagtttaa cccaggataa
     9541 aaagtatgat agaataaaga agcaattttt agcagaaaag aggcatttta atgacggaaa
     9601 atttgaacca gacgatcatt cagcttgtac aaaaagaact ttcagactat cgtcctaagc
     9661 agttgactac tgtacttaat ttgttaaatg aaggaaacac tgttcctttt atcgcgcgtt
     9721 accgaaaaga aatgactgga agtcttgatg aagtccagat tcgtgaaatc gaagagcggt
     9781 atgcctatct tgaaaactta gaaaaacgta aaactgaagt gattcggcta atcgatgaac
     9841 aagggaaact gactcccgag ttagaagcag aaatcaccca agccgtgaaa atgcaacaag
     9901 tggaagattt gtatcgtcca tacaaacaaa aacgacggac aaaagcaacg attgctaaag
     9961 aaaaaggact tgaaccactc gcgaagtggc tgatgcagct tacagatgga gaggtgcaat
    10021 ctgaagcaga aaaatatatt gacaaagaaa aagaagtctc ttctgccgaa gaagcgttgc
    10081 acggtgctca tgagattatt gctgaacaag tcagcgataa tgcaaaattt cggacttgga
    10141 ttcggtctta tacgtataac aaaggtatgt atgtcagcaa tgtcaaggat gagcaagcag
    10201 atgaaaaagg cgtatatgaa atgtattatg actttgcaga acccgtccat aaaatggttt
    10261 ctcatcgaat attagctact aatcgtggag aaaaagaaga tattctgaaa gtattctttc
    10321 aagtagatga agcagcaatt ttagcttact tggatcgcca aatagtcaaa aatcctgcct
    10381 ctccttcttc ttcattcgtc agagaagcct atcaggatag ttataaacgc tttattcagc
    10441 cagcaatcga gcgagaactg cgcaatgaat tgactgaaaa ggcagatgag caagcaatcg
    10501 ctattttcgg cgaaaacctc cgtaatcttt tgttgcaacc gccactaaaa ggtaaagttg
    10561 tcctgggatt tgatccggct tatcgtactg gatgtaaact agcagtcgta gatgcgacag
    10621 ggaaagtttt agcaatcgaa gttatttatc ctcataaacc tgcagcgcaa gcaaaaagag
    10681 aagctgctgg accagctttt atccaattaa ttaataaata tcaagtagat atggtagcta
    10741 tcggaaatgg tacagccagt cgggaatctg aactttttgt ggctgagcag ttgaaatccg
    10801 ccgaccataa aacctattac gctatcgtca acgaagcagg cgcttctgtt tactccgcta
    10861 gcgaaattgc acgaaaagaa tttccgcatc tacaagttga agaaagaagt gctgtttcta
    10921 ttgcccgtcg cctgcaagat cctttagctg aattagtcaa aatcgatcct aaagctgtcg
    10981 gagtaggcca gtaccaacat gacgtttctc aaaaacgttt ggctgaacaa ttggattttg
    11041 ttgtggaaac agcggttaac caagtaggtg tggatgtgaa tacagcaagc ccgcagctct
    11101 tgcagcatat atcaggattg aataaaacaa ctgcccaaaa cattgtcatt tatcgtgaag
    11161 aaaacggaga attcaccgca cgaactcaat tgaaaaaagt gccacgctta ggaccaaaag
    11221 catatgaaca agcaatcgga ttcttgcgag tccctggtgg gaaaaacatt ttggacaaca
    11281 caggtatcca tcccgaaagt tattctattg caaaagaaat attaacttca gtccaacttt
    11341 cagaaaaaga gcttggtaca gaagaagcag tagaaaaatt gacacgatta tccgtagaga
    11401 aactggctga aagcctatca gtcggagaag aaacgttagc cgatatttta gctgggctga
    11461 cacaacctgg acgagatatg cgtgatgaga tgccagcgcc cttattacgt acagatgtat
    11521 tgagtatgga agacttgaaa ccagggatgg aattgactgg aacggtccgt aatgtcattg
    11581 acttcggcgc atttgttgat atcggtgtga agcaagacgg acttgtccat atatcgaaac
    11641 tcagcaaaaa attcgtcaag catcctacag atgtcgtgtc agtaggagat atcgtaacag
    11701 tttggataga acaagtcgat acgaaaaaag gcagaatcag tttgacgatg ctttcccctt
    11761 atgaagagta acaatgagga gtaacaaaaa ttgacacaag aagaactgca gcagttagta
    11821 gaagagatat cattaaaaag cttccagctt cctttcaagc accaagcaat gttcaatcca
    11881 cgcttacgta caactggcgg gcgctatcat ttaaacgatc atcatttaga ttttaatgcg
    11941 aagctatttg aagagtcaga cgaagagacg attgcaggaa tcatcaaaca tgaactttgc
    12001 cattatcatc ttcatctagc tggaagaggg tatcagcata aagatatgga tttcaagtat
    12061 cttttgaaaa aaacaggagg gttgcgctat gcaccagcct tgacgaagaa acagataaag
    12121 atggagtatt atcgatgcca agattgttct gccacgatct gccgcaagag aagaatcgat
    12181 gtacgcaaat atcgttgtgg aagatgtcat ggagaaatca aatggattga gacaaaaaga
    12241 gaagacttta atgaagcaca aaaaatcaga tgaaaggata gaaggccttt ggaaaaaagt
    12301 gagcagagga atctaaaaga ctggaatcag ctattaaatt ttttagccgc acctgaagag
    12361 ggaaattttg aggaactgac ggcacctaca cttattttag ctggaaactg tcttcctatc
    12421 ttagctgata aagcagcaca aatgtattta aatggccaag tagatcaatt gtttttggtc
    12481 ggaggggtgg ggcatgcgac tagaatcctt tatgagaatt ttgaaaagca aggatttcat
    12541 tttgaagatg gcatgagtga aagtgaaatc tgtcgtcagt atctaaaaga agtctatgat
    12601 ttgcccgata aggcttttct gatagaatcg aagtctacaa attctggaga gaacgccact
    12661 ttttcactgg agattcttca ttccttagga gctgtaccag aaaaaatctt attgatgaat
    12721 gatccgacac tgcaacgcag gactcgagca acttttgaga aagtatggca aaatgaacaa
    12781 actattttcg cgaatgctgt gccatttgtg ccggaaatcc ttcacttttc tgaagagatc
    12841 atctttacag caaaagaact gaatcatcaa tggcctaagg aatatttcca tgcgctagta
    12901 ttaggagaaa tggaacgtct ccatgacgat gagaacggct atggtccgaa aggaaaagat
    12961 tttattcctc acattgatat atcagaggaa gtttggtctt cttacaccag aattaaagag
    13021 tcaataaaaa cggatttttc tcgtacttga ccattttagc aagcgaatcc tcctttccaa
    13081 ataaatttgg ttgaaatttt caatcgttta taagataatg aggagcgtgt tgaatgtaat
    13141 agctaaaaga atggacgcta gataagagaa gaggattcaa atggaaaatc aaaataaatt
    13201 gtatcatttt gttggtatca aaggttcagg aatgagctcc ttggctcttg ttttacatga
    13261 acaaggtcta aatgtccaag gatcagacat tgaaaaatat ttctttacac aaagagattt
    13321 agaaaaagca aatatcacga ttctgccatt taacgcagat aatgtaaaac cagggatgac
    13381 gatcattgca ggaaatgcat ttcctgattc acatgaagaa atccagcgag caaaagaatt
    13441 aggtttggaa gtgattcgct atcacgactt tattggtcat tttatccaaa attatacgag
    13501 tatcgctgta acaggctctc acggaaaaac aagtacgact ggactgctct ctcatgtatt
    13561 gagtggtgtc cgtccaacaa gttatctaat tggagatgga acaggacatg gtgatccgca
    13621 agcggaattc ttttcatttg aggcctgtga atatcgccgt catttccttg cctattcacc
    13681 agactatgca atcatgacca atatcgattt tgatcatccg gattattata caagtatcga
    13741 cgatgtattt acagctttcc aaacaatggc tggacaagtg aaaaaagcta tttttgcgta
    13801 tggtgacgat gcttatttac gcaaattaaa agcaaatgtg ccgatttatt attatggtgt
    13861 cacagaaaac gatgatatcc aagcacgaaa catcgaacgc acaacttctg gttctgcttt
    13921 tgatgtctat catggggatg aatttgttgg gcacttcact gtaccagcat tcggtaaaca
    13981 caatatctta aatgctttag gtgttattgc agtagcttat ttcgaaaaac tggatctgaa
    14041 agaagttgca gaagaaatgc tgactttccc aggagtaaaa cgtcgattca gtgaaaagat
    14101 cgtagcagac atgaccgtag tcgatgatta tgcgcatcac cctgcagaga tcaaagcaac
    14161 gattgatggc gcacgccaaa aatatccaga taaagaaata attgcagttt tccaacccca
    14221 tacgtttacg cgtacgattg cattgatgga tgaatttgca gaagcacttg atttagctga
    14281 taaagtttac ttatgcgata tttttggttc ggctcgggaa gaacaaggaa acgttaagat
    14341 tgaagacctt ggagcgaaaa tcaaaaaagg tggagaagtc atcaaagaaa ataatgtatc
    14401 tccattgtta gattatcatg atgcagtagt aatcttcatg ggtgctggag atgttcaaaa
    14461 atttgaacaa gcgtatgaaa aacttttaag cagcacgacg aaaaatgtac tgtaatacaa
    14521 ttactgcagt gtccttataa aaatagaaag agggggagtg gcaaaaatct tgccaagccc
    14581 ccttttttgc aacttatgat aaacggtgtt caaaagcttg catctgcggt aataagccca
    14641 atcaaatcaa aaacatgaga agctgttttt tcttggctgt tcttattatt tgatgcagga
    14701 cagctttttc acgacctctg taaactatag gaatctgtta aatcaaggga gcagaacttg
    14761 ccttttacgc tacttttggt acaataatgt atgattaaaa ataaactgga gggtttctat
    14821 cttgaacata ggtaagccga gaaaactagg aaaaacaata aatgaaatcg aggaaggcga
    14881 ctcgttatcc ttaacagaat ctattgaaga taaccagctt ttgctgtatt tgggattgac
    14941 gaatgatgca aatcctttgt atatccaaca tgactttgca caaaaaacag aatatcaaca
    15001 gccaatcgtt ccatcagtga tgctgatggg gatcatcaca agtgcaattt caaagcatct
    15061 tcctggacca ggatcacatg ttgtcaattt ttctgtcaat tttattgaac cggttttcca
    15121 ttatgaaaca ctgacttttc agtttgaggt cataaaagta gataagatga aggatgtggt
    15181 gacgatttct gtagaagcgg agaatacgaa cgaagatcgt gtgttggatg ctgtcgttat
    15241 ggtccaaccg ccacaagttc ctgaattgga aatagcaatc gaaagtgaag gtgaattgaa
    15301 tgaataatcc aagtacatca atgtcaggta tcaatcgttt ttatgcaaaa gtttatggat
    15361 ttttaggtat gggacttgcc cttagtgcag tcacttctta cttggctctt tgggtatttc
    15421 ctttgcaatt agcaactttt atcaataatt ttccactagg ctttgtgggt ctgtggatcg
    15481 ttgaactgat tttagtaatg gttctaggcg taaaagcaca aaagaatccg agcttagcaa
    15541 tcggtggatt tattgcctac tctcttttga atggcataac attagcggtt actcttgcat
    15601 actacgatat tggaacagta acgcaagctt tcttgacagc tactttgatg ttcatgggga
    15661 tgtctgttgt cggagtaaca acaaaaagag atcttagcgg ggttggaaga gcaggacagg
    15721 cagctttaat cggagtgatc attgcactag tcttgaacat cttcattttg agaagtagcg
    15781 tagttgagct gttcatctcc ctactgttag tcgtcatctt tgcagggatt acagcttatg
    15841 ataaccaaag catccgtaat atctatgtcc agacaaacgg aacagcacat agtggaattg
    15901 ctgtattcat ggcattgaag ctgtatttgg actttatcaa cttgttcttg gcgtttctga
    15961 gaatctttgg acggaacaac taaaaaagaa aaaaattcat cagttggggc tataccgaat
    16021 tatttggtat ggtcccgctt tttcttttcg cattccgcag gattctttgt tagaatgaat
    16081 aagaacttta cagtaaggag ttaagaagat gacaaaaaat aaattattac tcgttgatgg
    16141 gaacagtgtg gcttttcgcg cattctttgc gcttcacaat tctcttgaac gtttcaaaaa
    16201 tagaaacggt cttcatacaa atgcaatcta tgcattcaat acgatgtttg aaaatgttat
    16261 gcaaaaagag caaccgactc atgttctggt tgcgttcgat gcaggaaaaa cgacttttcg
    16321 gacagaaatg tatgcggagt acaaaggtgg aagatccaaa acacctggcg aattcaaaga
    16381 acaaatgcca tatatacgtg atttgttgac aggactaggg gtacagtatt acgaattgcc
    16441 caattatgaa gcagatgata ttatcggtac tttggcagaa aaagtagaca aagatcaatt
    16501 tgatgtcgtc gtgctttcag gtgatcggga tttgactcaa ttagctagta aagaagtaaa
    16561 agtggatatc actgtaaaag gtgtcagcga tatcgaaagc tatacaccag aacatgtagc
    16621 ggaaaaatat gatgggttga cgccaaaaca gattattgac atgaagggac tagccggaga
    16681 tgcctctgac aatatccccg gtgtgactaa aatcggtgaa aaaacagcta tcaagctatt
    16741 gaaacaatat ggctcagtcg aaggaattta tgaacatatc gatgaaatga agcaaagcaa
    16801 aatgaaagaa aatctgataa atgacaaaga gcaggctttc ttatcgaaaa aattggcgac
    16861 catcaatact tcagcgcctg tggatgtctc tatcgactca ttgaagtatg aagggaaaaa
    16921 tctcgataaa ctcgttccgt tttataaaga aatggatttc aatcagttcc tttctaaatt
    16981 gaatatcgta gaagaagaag taaaaatgga tgatattttg tttgaagtcg ttcatgaatt
    17041 caaagaggaa atgtttacta cggatatggc gttgtacgtg gaaatgatgg gcgacaatta
    17101 tcatacagag gaaatcgtcg gagtagcgtg ggggacagaa aagaaaattt atgtcacgaa
    17161 cgatctatct gtattcgaaa accgagcgtt ccattcttgg atcactgatc cgactcggct
    17221 gaaaaaagta tatgatgcga aacgaactta tgttgcttta aaccgctata ctggaaaaac
    17281 gaaaggaatc gattttgatg tcttgctagg tgcatacctt ctcgatacga atgaaaaaag
    17341 cacagatatc gaaggaatag ctgctcatta cggatacaac gatatccaat cagatgaagc
    17401 tgtatacggc aaaggggcga aaaaaggttt accagaagaa gaggaactct tttttgctca
    17461 tttagcgcga aaagtagctg caatcaatgc gttgacacca aaattgagcc aagaactggc
    17521 agaaaaaaac caagaagatc ttttccggaa aatggaactg ccattgtcta tcattttggc
    17581 agagatggaa ataagcggga tcaaagtaga tgcgactcgc ttacaagaaa tgaagggcga
    17641 gttctctgct cgcttaagag agatcgaaca aaaaatctac gaagaagccg gcgaagaatt
    17701 caatttgaat tcaccaaagc aattaggagt gatcttattt gaaaaaatgg gattacccgt
    17761 tatcaaaaaa acaaaaactg gatattccac agccgtagat gtactggaac agcttcgtga
    17821 acaagcacca atcgtagagg atatcctcac ctatcgtcaa attgcaaaaa ttcaatctac
    17881 ctatgtcgag ggactgctga aagtgatcca atcagatgga aaagtgcata cccgttatgt
    17941 ccagacattg acccaaacag gacgattaag ctctgttgat cctaatttgc agaacatccc
    18001 gattcgatta gatgaaggga gaaagatacg tcaggcattt gttcctagag aaaaagactg
    18061 gctgatttat tcttctgact attcacaaat cgagttacgc gtacttgcgc atatctcaaa
    18121 tgatgaacat ttgaaagctg ccttcctaga aggtcaagat atccatgcca gcacagcgat
    18181 gcgtgtattt ggaatcgaaa aggcagagga tgtcacacca aatatgcgta ggcaggcaaa
    18241 agcagtgaat tttggtatcg tgtatggcat ctctgattac ggactttcac aaaatctagg
    18301 aatcagccga aaagcagcac agcaatacat cgatacgtac tttgaaaaat acccaggtgt
    18361 caaagaatat atggaaagaa tcgtacgcga agcaaaagac caaggctacg tcgaaacgct
    18421 gtatcaccgc cgtcgatatc tgccagacat caattcaaga aattacaata tccgttcttt
    18481 tgcggaacga acagctatca atacaccaat ccaaggaagt gctgctgata ttttgaaaat
    18541 cgcgatgatc gaattggata aacgattaaa agaaacaggt cttcaagcta cgatgctgtt
    18601 acaagttcat gatgaacttg tcttcgaggt accggaaaaa gaacttgaat cattagataa
    18661 attggtgaag gaagttatgg aacaagctgt ttctcttcat gtaccactga tcactgacag
    18721 cagttgggga aaaacgtggt acgaagcaaa ataaacattg tttaagacag agcaatataa
    18781 tgaaggtgaa aagaaaaaat gccagaatta ccagaagtag aaaccgttcg taaaggattg
    18841 gaacggttag tagtaggaaa aacgattcaa aaagttcagg tcttgtggcc caagatcatc
    18901 gagcaaccag agacacccat ctttgaggct tctcttgttg gcgaaaccat ccaatccatt
    18961 ggacgtagag ggaagttttt aatttttcat ctcgatcatt gtgaactgat ctcacacttg
    19021 cgaatggaag gaaaatatca atttacgaaa gaaaatacac caatcgataa acatacgcat
    19081 gtacttttct tttttgagga tggaagccaa cttcgctaca acgatgtacg aaaatttggt
    19141 cgtatgacaa tcgtcgaaaa aggagcaagt gcaacttacc gaggaatcat gaaattggga
    19201 cctgagcctt tgccagatag cttcttatta gcagatttcg caaatggact gaaaaagtcc
    19261 cacaaagcaa tcaagccatt gctgctagac caacgtctag tgactggtct aggtaatatt
    19321 tatgtagatg aagcattatg ggaagcgaag atccatccag aacaaccggc gaacacactg
    19381 cgccccaaag aggtagaaca attacgtcta tcgatcattg atgttttgga tcgtgcaata
    19441 gaagccggag gtaccacgat tcgcagttat ttgaatgcat taggagaatc aggcggattt
    19501 caagtagcac tgcatgtcta tcagcaaact ggcaaaccat gtatacgttg tggaacgccg
    19561 atcgtgaaaa caaaagtggc acaaaggggg acgcactatt gtccgaattg tcaaaggcta
    19621 aaaatcgcaa agtaggattt gttttaggtt tgacgggtgg aatagctacc ggtaaaagta
    19681 cggcagccaa agtctttcag tctcatggat ttcctttgat cgatggcgat gtgattgcca
    19741 gagaaactgt tgagcctgga acgcttgctc tgaggaaaat tgtatcagtg tttggccaag
    19801 aggtattgca gcctgatggg caactagatc gagggaaact tgggatgatt gtttttccat
    19861 caaaggaaaa acggcaaaaa cttgatcagc tattagatcc gtttatccga aaagcgataa
    19921 aagatcaaat cgcctctcta agttccaatc atcctttagt aattgtagat atcccattgc
    19981 tctacgaagg tcattatgac cactatatgg atgcagtagc tgtcgtttat actacgccag
    20041 aaactcagct tcagcgtttg atgaaacgta atcaactgac gctagaacaa gcgcagcaga
    20101 gaattagtag tcaacttcca atcgaagaaa aaaagcagcg tgcggatatt ttgttcgaca
    20161 acaatggaac aaaagaaaaa cttgtgggac aaatcgaaaa ttggcttttt gctaatcgct
    20221 ttctttgagt atctgtgtca attttgctat cctgagtata tagaaagtga gggatagcga
    20281 tgggatcatt aaaaaatcaa aaggataaag tcgtaggtaa cgcaaaagaa aaaatcggcg
    20341 agatgctcaa taaagaaaat ctaatcgatg aaggtcgtac gcaatcagaa acagcagaag
    20401 aaaaagaaaa gcagtaccaa gcaagaatcg atgaaataga agaccagcag gcagaagaag
    20461 aagcgaagcg gcaagatttg actcaagaac gaaaaaatcc gacacctgat cgtagtaaaa
    20521 caccgctccc agaaagtgac cacattcccg atgagcaaaa aatcgaggaa cagcgaatga
    20581 aacactatac aggaatcgaa gagaagttat aaaatagtaa aaaatcgaga tgtgacttga
    20641 agcagatgag aaggtgttca tctgcttcaa gttttttgtg ctagatgact aaatcagctt
    20701 ttgtgtaagt tatttctcag taatcaaggt gatcagtatt ggaaaattga aatttagtaa
    20761 ggacagggga cacaattacg catgaaagta gaaaaaattg ttcttatatc cgtgtttttt
    20821 gggtaggaca gtcgcgtttg tgatttgttt cgtgttataa tacaactagt tgtaaagaaa
    20881 gacacatcct ttatataaaa tgcgatgcaa gaggtgagac aaaatgagat gtcccagatg
    20941 tcaacataat aattcacgag taatcgacag ccgtcaagca gatgatggac gtgcgatccg
    21001 tcgccgtcgc gaatgtgaga attgttcgtt ccgattcact acatttgaac gaattgaagc
    21061 tgctccgtta ttagtaatca agaaaaacgg ggaacgcgaa gagttcaatc gcgataaaat
    21121 tttaagagga ctcatccgtt cagcagaaaa aagacctgta gctatggaac aaatggaaca
    21181 aatcgtcaac catgtcgaaa accgcgtacg cagtctcgga gaaaacgaag tatcgacgaa
    21241 tctaattggt gaatatgtga tggaagattt agttgattta gacgaaatcg cttatattcg
    21301 ttttgcaagt gtttatcgcc agttcaaaga tatgtctgtt ttcttaaaag agttgcaaga
    21361 tatcgtggat aaagcaaaag aaaataataa agagaataat aaagaaaaca attaagaaac
    21421 aaaaaggagg catttccttg gaaaatgctt ggaaagagct tcaaccaaaa aatatttacc
    21481 aaggaagaaa agcggctccg ctgagagaag acagcaagaa cgccttgctg tatctttatc
    21541 agccactaat cggcggagaa gccttgagta tctatttcac cctgttatca gaaatctctc
    21601 aagaatctgg caaaggtcct gaagggatgc atgcagatct gcttagtagt ctaggctgcg
    21661 gtatcccgca attttatgat gcaagaaaaa agctagaagg aatcggctta ctggatgttt
    21721 attttaaaga agatagtgat ctgggacctc gttttattta tgagctgtta gaaccactca
    21781 ttcctaaagc atttttcaaa gactctgttc tggcttttct tcttctggaa aaagttggtg
    21841 aacgacgatt ccagaagctt acccaattct ttgaacctaa aaggcataca gcagagggat
    21901 atcaaaaaat cacaaaaaaa tttttagatg tttatcgctt caatgaagca gtgtacgctg
    21961 ctaatcaaga aaacatcgaa tcgctgaata aatcttttga agaatctgaa tcagtagcat
    22021 tacttgaagc agattcgaca ttcgattggc agtttttgaa tgattggctg gcaaaaaaac
    22081 atattgcaag tcttgatgat ccaatcatca aacaagtcga catgtatcat cagctttacg
    22141 gtttcgatga attgacactt ggcgaactga tcagtcaatc ttatgacttt agtgaacaaa
    22201 aagtatctga aaaagaactg caaaaagcca ttttggcaat gcagagacgt ccggtgaagc
    22261 aaacaaaaga aacagttgcg gtttctgaaa acagtaatga accctcgtca aacgaacatt
    22321 tgacaaacgc agcgcttcag ctgataaaag aagcacagag cattccaccg atgaaatatc
    22381 tggaagcaat caagtcagaa aaaggcggat atgtttctaa acaagaaaac tggttactgc
    22441 aagatcttgt ttctcaatca ggtctttcca gtagcgtgat caatgttttg ctgaattatg
    22501 tactagtgat caagaataat gctagcttaa atgccagtta tgtaaataca gtggcaaatg
    22561 aatgggcaca aaagaaaatc gccacagcag aagaagcgat ccagcacatt cggcaaataa
    22621 gtaatcaagc aaaacaatca aaacaaaaga agcaaacaaa ttatcaaact ggcaagcgaa
    22681 atgttcgacg ggaaaagctt cctgattggg tcaaccagcc aaaagatgaa aaacagatca
    22741 gcagcgagaa aaaagcagag attgaccgcc gttttaaaga atacctggca aaaaaggagg
    22801 gtgatatcta gtggaagacg taggcaaaga attgaagagg atcatcagca aacgcaatta
    22861 tcaagaaaag tatgctgaaa tgatcgctga agtcttaaat gatgcggatg ttcaagcttt
    22921 tctaagcgca caccaagaag aattgacaca agcggatatt gaaaaaagtt acgctaaatt
    22981 gtatgaattc gtgcaagaaa agcgtaaata tcaaaaaaac gatccaacga tgatcgctcc
    23041 cggctatgag ccgaagctga cgttgaattt tcattatgtg gatgtcactt atgtaccaac
    23101 ggaagcattg ttagcacggc aaagacaaga agaaatcaga agccgagtaa aagcaatgga
    23161 tatgccaaaa gatattcaat cggcttcttt tgaaaacttt gaacgtacag atggacgagg
    23221 atatgcgagc ttagaagccc tagattttgt agagaaatat actgctgatc caaaagggta
    23281 tcataaagga ctgtatctag taggaagttt tggtattgga aaaacatatt tattaggagc
    23341 aacagcgaga gaattagcga ttgctggatt caccacgacg ctagtccatt ttccgacatt
    23401 tgccgttgag atgaaacagg caatcggaaa agatcaagtg gcagaaaagt tagatgcagt
    23461 gaaacgttca cctattttga tgatcgatga cattggtgca gatgcgatga gtagttggat
    23521 acgagacgaa gtattcggtg ttatccttca atatcggatg caggaacagt taccaacctt
    23581 cttctcatcg aattttacaa tggatgaatt ggaacagcat ttgtccgtca ctcaacgtgg
    23641 agatgaagag ccgctaaaag cgaaacggat aatggaacgc atacgttatt tgacaaaaga
    23701 aatcgaaatg actggtcgca accgacgcaa tggttgaaca gttgacaagt ccaactgaca
    23761 tttgacctag tagtaaaagc aggtcagcga atcattatat ggacagaaat gaccggagac
    23821 aatcaccgca acaagtaatg cagaaactta aacggaggat tttttatgag ggctattttt
    23881 tctagtatat ctgtagttgg tctatttttt cttttagcag gctgcggtag cgcagatagc
    23941 aacacaggtt ctgttgattc gattgatgcg ggtcaaacag taaaaacaag cagtacgaaa
    24001 acggagagac aaagcatatt tgtcggaacg attgaaagta tcactcaagt agaagcagaa
    24061 gaagaaacgc ttcagttgaa actcgtcgat gtcatggcca aagaagatcc agcgaatatg
    24121 ggaacgtcat tcagcaatga cggagtgatc ttaaatgcta ctgctgaaaa aataagcgtg
    24181 gacataaatg aattgaaaat cggtgacaaa gtccaattta cattagttga gatgccgatc
    24241 atgacgatgt ctatcccacc gcaagttcct ggagattcga ttattgatgt ttcattgaac
    24301 aaataaccaa taacattttt tcaaaaataa gaaaatgttg ttttatagaa cgaaaaggta
    24361 tattttttaa ggagatatgg gaattttttt attcctagtc tccttatttt atttggaaaa
    24421 tgctataatt atctagaagg agtgaagcta tgaaccattt agatttatct cagcgcttag
    24481 ccgcagtggg tgactttgtc cctgaatccg ctcgtttagc agacattgga tcagatcacg
    24541 cttacttacc cgttgcattg atattaagag gaaaaatcga atatgcagtt gctggtgaag
    24601 tcgttcaagg tccttatgaa tcagcacgta agcaagtcaa aaaagatgga ttagaagacc
    24661 gtatcaccgt acgccttgca aatggtctag atgctatcca gccacaagat ggtattacag
    24721 ctgtcacgat tgcgggtatg ggaggttcac tgatccgaga tatcctagaa gctggcaagt
    24781 tgaatcaacg cttaagcgga caagaacgtt tgatccttca gccaaacatc ggagagcgta
    24841 cattacgatc ttggctgcaa gaaaatcagt ataaaatcca atcagaaaaa atacttgaag
    24901 aaaataaaaa aatatatgaa atcattgtag ccgaaaaaga acaaaaacca gttacttaca
    24961 atgaaatgga gctgatgttc gggccatttc tgcttgaaga gaaaagtgag atcttcaaat
    25021 caaaatggac aagagagctt caacaaagaa aagctatccg tgaacagctc aaacaagcag
    25081 ctaatcaaga ggcacgtcaa aaacaaatcg agcaggaaat ccaaatgatt gaggaggttt
    25141 taaagccatg acaatcagcg gacgcacttt catccaaaag tttgaaagct attgtcctca
    25201 gtggctagct gaagaaggag acccagtcgg actgcatatc ggaacattgg ataagccaat
    25261 ccaacgagta atgatgacat tagacgttcg tccagaagtg gtcgaagaag caatcaagaa
    25321 aaaaatcgat ttgctgattg ctaaacatcc tccaatcttt cgtcctgtaa aacggctggt
    25381 tactgatcag ccacaagaaa aaatgtatgc agatttgttg aaacatgata ttgccgtcta
    25441 tgcagcacac acgaacatgg atattatttg ggatggactg aatgactggt tttgtgaact
    25501 tctcggtatt gaagtggaga gttatttagt aaagactcat gagattcatt ataaaaaact
    25561 ggccgtttat gtacctgtgg atcatgcaca gaaaatgcgt gaagtattag ctgcagctgg
    25621 tgctggtaca caaggtgatt ataccggtac aagttttacc tcgattggac acggtcgatt
    25681 tactccggaa gctggtgcac aaccagcgat tgggaaagta gggaagacag aacaagttca
    25741 agaggcaaaa gttgaggtta ttttgccgga aactatcgaa aaacaagtga ttcaagccat
    25801 gcggtcagct catccttatg aggaacctgc ttatgatctt ttcgctatag atgaaccagt
    25861 cgaaatgttt gggttaggac gagtaggtga attgccgcaa gaaatttcta tagaggcatt
    25921 tgtagaacaa gtaaaagaag cgttccaact agatggactg agaatagtcc agccaaaaaa
    25981 tgcaaaatcc tctgtgaagc gcattgcgat ttgcggtgga agcggtgaaa aattttatcc
    26041 gcaagcaatc gcccaaagag cagatgtcta tatcacggga gatatctatt atcatacggc
    26101 tcatgatatg caaagcgctg ggttgattgc aattgatccc ggtcattata ttgaatcgtt
    26161 atgcaagcaa cgatttatcg agaaatttga atcttggaaa caagaagaaa attgggatat
    26221 taactttttc gtttctgaaa caaatacaaa cccatttcaa tttaattaaa aggagagaat
    26281 actatgtacg aaaatctttt gccacgtttt ttacgatatg tcaaaacaga aacacgctcc
    26341 gatgcaacaa gcaaaacgac tccatcgact cagacacaag ttgcttttgc gcaagaattg
    26401 aaaaaagaat tagaagagtt aggcttagct gatgttttct ataatgaaga taacggattc
    26461 gttatgggaa cattaccaag caatgttgat catgaagtgc gttccattgg atttatttcc
    26521 cacatggata cagcagattt taatgcagta ggagtcaatc cacaaatcat tgaaaactat
    26581 gatggcgagt ctacgatcgt actagatgcg gaagaacgct atacattgaa tacaaaagat
    26641 tttccaaatt tgaaaaatta tgaaggccac acattgatca caacagatgg cagtacatta
    26701 ctgggagcag atgacaaatc agggattgcg gaaatcatga ctgcaatgga gatcttgatc
    26761 aataatcctt ctatccctca cggtaccatc aaagtggctt ttggtcctga tgaagaaatc
    26821 ggtgtcggag cggataaatt cgatgttgag caattcgatg tagattttgc ttatacagtc
    26881 gatggtggtc ctttaggtga gttgcagtat gaaacgttta gtgctgctca agcaaatatt
    26941 acgatccaag ggaaaaatgt acatccaggg acggcaaaag atacaatgat caatgctcta
    27001 cagttagcaa tcgattttca taatcagctt ccagccgatg aagttccaga aaaaacggaa
    27061 ggatacgaag gtttcttcca tttgatggca ttggatggga atcctgaaga agcttctatg
    27121 agttatatca ttcgcgatca tgatcgtgaa aaattcgaag cacgcaaagc acaaatcaca
    27181 catatccaag aagagttgaa tcagcgattt gatcaagaac gaatcaaagt agatatgtat
    27241 gatcaatatt acaacatgaa agaaatcatt gaaaaagata tgagcatcgt ggaattagcg
    27301 aaacaagcaa tgatcgagct tggtatctct ccagtgatcg aaccagttcg tggaggaaca
    27361 gatggttcaa aaatctctta catgggtatt ccgacgccaa atctatttgc cggaggagaa
    27421 aatatgcacg gacgattcga atttgtttct ttacaagtaa tggaaaaagc aacagacgtg
    27481 attgtaaaaa ttgcagaatt gaacacaaag agttaaaatc gaaaaagaac agcttatgac
    27541 aaggcgttcg tcccaatgat ggaatgtcat ctgtctaagg ctaaagggca ggacaatgga
    27601 attggttgtc ccgccctctt ttttgaagag taaataggag gtaaagaatg gaaaagctgc
    27661 tagtttttta taacaaaagt tcagggaaag atgagggtga gaaattagca cgctggtttc
    27721 aagattatgt aaaagaaaag cagccagaat tatatgtaga actagctgaa actggcccat
    27781 cgattgatga tgcggaatta gtcaagaaag cagaagccat agaagctgat actttagtaa
    27841 ttataggtgg agacggcacg attcatcata tcgtccaagc gttccaaaaa acattatctc
    27901 aataccatgt cggattactt ccaggtggaa ctgtcaacaa ccttgcacgt gttcttgaga
    27961 ttcccctcaa aaaagaagaa gctgctgacg tgatcctgga aggcaatgta cggaaaatag
    28021 actatggtca agtcaatgat gaagtcatta tctctacact gacaatcgga atcttagcag
    28081 atacagcagt ttggatcagt caagaagaaa aacagcgtta cggctcgtgg atctttatca
    28141 agaagttttt taagttattg ctgaagaaga aaaaatatca tttggattta gaaacagacg
    28201 aggagcattg gaaaggaaaa tcccaactgt tgacagtcac gatgtctaac tccgtgggcg
    28261 gttttacaaa ttttgacgac tcagcgaccc tagatgatgg aaaatttcat gtaacgatcg
    28321 taccttcctt agatattttc cgatttattt tttatttgcc tagaatcatg agaggcaaat
    28381 tctatacgat ccccggcatt acttatttca cagccaaacg catgaaaatc caagcgcagg
    28441 aaaaatctgt gggcactcga acggatggag acacgacaga tgatcttcca gttgaattat
    28501 ctgttgtatc aaaaggatta acagtttatt caccaaagaa agaagaaaaa gcttagaaat
    28561 agtagttaac agaaagttgg aagaagagta atggatgtat tgttacacaa tcctttgtgg
    28621 ttttaccttt tcattgtgaa tttttactta ttttgtctga tggggtatga taaacatcag
    28681 gctagaacta gcggctggcg tgttcctgag aataatttga tatttgtcag cctgttaggc
    28741 ggtggtttgg gaggattgat ctctcgaaaa gttttccatc ataaaactcg gaaaaagaag
    28801 tttactatag gattcgctgc aggtgtactt gttgatttga ttctcattta ttttttccat
    28861 taaggagcag gagatgtcgt ctaaaggaac gaaaactaaa atcattctga atctgctttt
    28921 gctgattgtg atttttgcca ttatttatta tttaatcaat caatcatttg cagatatctt
    28981 tgccgaattg ctgtctacca gtgttgttgt tttggcagcg gctgttatat tagggacagt
    29041 ttaccaaatc gctgaagggc gctcaatcaa agaaattgct gaacctttcg cgccgaattt
    29101 tacaacgaaa gatgggttct tgacctctag ctatattgcg ttttaccgaa tcgtttcgtt
    29161 tggtacagga acgctgatct cggagattta tttttataac aaaaaaggaa tgaagctatc
    29221 ccagggagca ggggtgacag cactccatat gattatgtac aaactggcag tgatcactta
    29281 tgcattagct ggcttggtca tccaattctc tcttttttat tctaatggtc catcaatgat
    29341 ctggtttatc atcgctggta tccttttgac gatcgtgatt gttgcctttt tattggcgat
    29401 gtccgtcagc ttgaatgttc aaatattttt tgtcagctta tcgaataagt tatttaaaag
    29461 tgagcgtttg cggaaatggg tggatacatg caatcagcag atctactctt taagggaaac
    29521 ggtccaaacc attatccaag acaggactgc gctattgcgg atttatctat ggaatatgtt
    29581 aaaacttgta ttttggtatg tacttcctta tttgattctg attgaaaacc atcctaaaat
    29641 agattttcta ctgaccattt cgtttatcag ctttgcagta gtgctttcag gggttattcc
    29701 tacgcctgct ggtattggtt cctttgaatt tgtctatttg ttattattca gaccagttgt
    29761 tggaacagtt gacgcagttt cttcgctttt actgtatcgt ttcagttcct ttatcttgcc
    29821 atttctctat ggatttgtgt atgtgattgc tgaacggcga agagtgatca aagaagaaat
    29881 aatagaagta aaaaaagaga ataaagaaaa tcaagggtag gtcttttata agatctaccc
    29941 tttttatcaa atcaaagaaa aacgttatgg ataagataat tttacgtttg tttggctctt
    30001 tttttatata catacaatca attttgtttt tttaagattt atataagtcg agaaaaaaag
    30061 tcaaaaaact atgtgtatat tttgaccaaa attgaccaaa gcgatataat agtttttgta
    30121 aagatcaaag aaataagtga tcttaccttt aattaggagg gtatacctgt atgaatattg
    30181 agaaaatgac tacgacgctt caagaagcga ttgctgaagc tcaacagatt gcggtcactc
    30241 gaaaacatca agatatcgac attgcccatg tatggaaaat ctttttacaa tctaatcatt
    30301 ttggtcgaaa tttctatacg gatgccggat tggatgtcga atcttttgaa catgaaattg
    30361 atcgtctact ggatgagtat ccagttgttt ctggtggaaa cgtccaatat ggacaaaacc
    30421 tcagccagaa tttctttcga ttattgaatg aagcagacca aatacgtgaa agcttcggcg
    30481 acgagtttct ttcaacggaa gtcgttattt tagcgttgat gaaattaaaa aattatccgt
    30541 taactgttta tttgaataaa aacggattat ctgaaaaaga attgcgtaaa aacatcgaag
    30601 agatgagagg aggagaaaga gtgacctcac aaaaccaaga agaacaatac aaagcattag
    30661 aaaaatacgg cgttgattta gtacagcaag tcaaaagcgg aaaaatggat ccaatcatcg
    30721 gtcgtgatga agaaatccgt gatgtcatcc gtattctttc acgaaaaaca aaaaataatc
    30781 ctgttctgat aggagaaccc ggtgtaggga aaacggcaat cgttgaaggg cttgctcaac
    30841 gtatcgtacg caaagatgtg cctgaaaatt taaaagataa aacgattttt tcattagata
    30901 tgggtgcatt gatcgctgga gcaaaattcc gtggtgaatt tgaagaaaga ctaaaagcag
    30961 tcttgaaaga agtcaaaaaa agtgatggac gtatcctctt gttcatcgat gaaatccaca
    31021 atatcgtagg ggcaggaaaa acagaaggaa gtatggatgc cggaaatctg ttgaaaccaa
    31081 tgcttgctcg cggtgaatta catttgatcg gtgccacaac tttagatgag taccgtcaat
    31141 atatggaaaa agacaaagcg ttggaacgtc gctttcaaaa ggtattagtc aaagaaccaa
    31201 cagtggaaga tacgatcagt attctgcgtg gattaaaaga acgttttgag atccaccatg
    31261 gtgttaacat ccatgacaac gcattagtag cagcagctac tttatctgac cgttatatta
    31321 ctgatcggtt cttaccggac aaagcaatcg atttgatcga tgaagccagt gcaacgattc
    31381 gggtagaaat gaactctatg ccaacggaat tagatcaagt tactagacgt ttgatgcagt
    31441 tggaaatcga agaagctgca ctgaaaaaag aatcagatga tgcaagtaaa aaacgcttga
    31501 aaaatttgca agaagaatta gctgaacttc gtgaagaagc aaatgcgatg aagatgcagt
    31561 gggaaacaga aaaagaagaa gtcaattctg tttcagcaaa acgtgctgaa atcgataaag
    31621 caaaacacga attagaagat gcagaaaata actatgattt agaacgcgct gctgtattgc
    31681 gtcatggtac gatacctcaa ttagaaaaag aattgaagga attagaagct aaagcaaaag
    31741 acagcgagat taagatggtt caagagtccg ttaccgaaaa tgagattgct caagtcgttg
    31801 gcagattaac gggtatcccc gtaacgaaac ttgtagaagg tgaacgagaa aaactaatta
    31861 aattgaatga aacacttcat aaacgagtga ttggtcaaga tgaagcagtt gatgcggtca
    31921 gtgacgcggt aattcgttca cgggctggat tgcaagaccc aaatcgtcct ctaggttctt
    31981 tccttttcct aggaccaact ggtgtcggaa aaaccgaatt agcgaaagcg ttagctgaga
    32041 acttgtttga ctcagaagat catatggtac ggatcgatat gagtgaatat atggaaaaac
    32101 atgctgtgtc tcgtctagtc ggagctcctc caggctatgt aggttacgaa gaaggtggtc
    32161 aattaacgga agctgtcaga cgaaatcctt atacaatcgt cttgttggat gaaatcgaaa
    32221 aagcgcatcc cgatgtcttc aatatcttgt tacaagtcct agatgacgga cgcttgactg
    32281 attcaaaagg gcgagtagta gatttcaaaa atacggttct gatcatgacc agcaatatcg
    32341 gttcacagtt actgctggaa ggcgtgactg ctgatggaac gattccagaa gcagtggctg
    32401 aacaagtcaa cacgctatta cgtggaaact tcaaaccaga attcttgaac cgaatcgacg
    32461 acacgatttt atttacacca ttgagcctag acaacgtgaa aggaatcgtt gacaaaatgg
    32521 tggcgcaatt ggcacaacgt ctggaacatc aagaaatcct gctgacaatc agtgatgaag
    32581 ccaaaacgtg gattgctgaa aatgcttatg aaccagcata tggtgcaaga ccattgaaac
    32641 gatttatcac taaggaagta gaaacaccac tagctaaaga aatcgttgca ggacatgtta
    32701 tgcctaaatc aaaagtaacg attactttac ttgatggaca acttcatttc aaaacagaag
    32761 agctagaaga aatcgtctaa tcttccattg agactataaa agaaaaaagg ggtctgacac
    32821 aactagtgtc agacctcctt ttttcaaata aacagtgttc cagaagtagt ttcttcgaaa
    32881 aataagccga aatttcttga agctgcccgc ttctgtcaca acctctttta ttaggtattt
    32941 ttcacttttt ctaatttata actttcaaag taacgctcat cttttttact ttgagaccat
    33001 gcaaacaatc ccattaaggc agcacctatc gtatttgtca gcaagtcgcc catcgtatcc
    33061 atcaatgctg ctcgtccgac aaacagtgtg ccatcagaag cagcaaaacg ttgaagattc
    33121 atgcctaaga actggtcgca taagaattcc cagaactccc aaaacacgcc gcaaagtcca
    33181 gcaaacgcaa agccgaataa gaggaacaac caaggactgg tttttgatat ctcagcatct
    33241 ttcatcaagt aaccaatcaa tccatagcca agagctgtca ggaccattgg actcaccgca
    33301 tgtaagattt tgtcccaaaa agagatgata ctgatcaaat gcatccctgt gcctaaaaag
    33361 acagagatga acaagaaaaa ccagtaaaac aaaacgattg ctgctggtat tttaagtttg
    33421 aaaactttca aaatgacttg tggcatgaaa atcaatgcaa tccctaataa agattccacg
    33481 ataaatgtga ttccttgaga agtcgaatat ttttgtgtga taaattcata aaaattatag
    33541 cagacaacga atacaccaaa agcaagtaaa gctatttgca cctttttgat ttctttaatc
    33601 actgaaagtc cctccatcta aaaatctttt tacttctgaa agcaactcaa tttctgaaga
    33661 aaccactttt ccgttcaatt tgatcaaacc tattgtatat aagttcaggt agtgaaattg
    33721 attttcagct gtttcttgta gtgcagcgat ttttttcggg tgggttccgc cttgctgtcg
    33781 agtatcagta tataagccga tcactgggat gcctttcgca taagccacac cgatttccga
    33841 tgctaccccg gcatcgatcg tcagcccatc tagtaaagca atcattaaat cactagccaa
    33901 cactttttct gtgtcagcaa gagcaatcat tcgactgtct gcataagcag ttttgtcatt
    33961 gattgcttca ttttcttgag gaagatagat cgaaagctca gaagagagct ctctgatttc
    34021 tttaactaac tgttggttat ataacaaatc acttttagca aacattggtg cggcaaaata
    34081 aattttcatc taaacatcat cctttttatc aaaaataatc gctaaagtaa gcttccatgt
    34141 ttggaatgat acgctctagt gacttcagtg tttcttcatc tgtttctaac cgttcgattc
    34201 ttgccaaata agaagcacgg cgataattca tcatcaagca agtcaatgtt tggatatcca
    34261 gtcgaacgga ttttcctata ggttcattta agacacggac ttgtccctgt tcatcccatg
    34321 ttaaagcgaa gacaccatta ttccaaggag cgacaggatc ttcaatgatg aaatgaaaag
    34381 catcagctgt tccaacaaac ggaaaccgtt gaaggaattc ttttacatca acgatccgag
    34441 ccataaaata tggttcgatc tgctctttga tctgactatc ttcaatcaaa aatgctaaag
    34501 gctcattttt ataaatatct ccatgtaccc agtagatcat ggaaaaatgt gcggaaataa
    34561 agttccataa gccatttcga gcttcttgat caagatagaa catttctttt acgtgaaata
    34621 tttcttcagc tacccagtag aacagaacac ctcttggttc atggttgcta tcgtagtaga
    34681 cagcggctgt gcgctcatct tcattttcga aacgccaata ctcttcccaa tgaaaatcac
    34741 tgcggaataa agcaccatgg ttttgttggg caaatttgtc ataaacggaa aatacgtctg
    34801 gatgatcaac tggtaatcgc tcaaccatac cacttactgg gatttgttta ggtagctgtg
    34861 tatctctgat tttaaaggaa agtttatcag acatgatttc ccatccttta cgccgatagt
    34921 aggggatact gtaaggatac aaataagaga tccattgctt attcttgcgc atattatcca
    34981 atgcaacgat aattagatct tgcatcaatc catggttagc atattctgga taagttccaa
    35041 ctccagtcac accacccatt ttataacgtg caccgtgaat attgacttca caaggataga
    35101 tagcgatttg agagatcagt ttattttcgt ggaaccatcc gaacactttc gatacttcca
    35161 aaatcggttt tttggaacgg ataaaagctc gtttattctc aaacccgctt tcctcgatgt
    35221 ctgcttcagt cacttggaac acataggaaa gcaattcatt gaattgatcg atatgttctt
    35281 gagtgaccgg ttttaattca agattttctc taaaatcttt ttgatccatt ttttcatctc
    35341 catttattag cttgataaca gtatagcaaa attctacaaa aaaaacttct atagctgact
    35401 aattaaaaac tctttaaatt actgcttttc gttggtataa tggaaagtgc tgattatatg
    35461 aaaagaggag acgctatgga tataaagaaa atgaaagaac gccaagagca gattcgtaat
    35521 ttttcgatca tcgctcatat cgaccatggg aaatctacat tggccgatcg tattttagaa
    35581 atgacgcaca ctgtgacgtc tcgcgaaatg caagatcagc tgttagactc gatggatttg
    35641 gaacgtgaac gtggaatcac gattaaatta aatgctgtag aactcaatta cacagcgaaa
    35701 aatggagaaa catatatctt tcacttgatt gacaccccag ggcacgtcga cttcacctat
    35761 gaagtctctc gaagccttgc tgcctgtgag ggtgccgttt tagtggtcga tgcagcacaa
    35821 ggaatcgaag cacaaacatt ggccaatgtt tatttagcgt tagacaatga tttggagatc
    35881 ctgccagtca tcaataaaat cgacctaccc gcagcagatc ccgaacgtgt ccgtcaagaa
    35941 atcgaagacg taatcggaat cgatgctagt gaagctgtat tagccagtgc caaatcaggg
    36001 attgggattg aagatattct cgagcagatc gtggaatatg ttcctgcacc aagtggagac
    36061 ttagatgcac cgctaaaagc tttgatcttt gactctattt atgatagtta ccgcggtgtt
    36121 gttctaaatg tccggatcac ggacggtatg gtcaaacccg gagacaaaat caaactgatg
    36181 agtaatggca aaacatttga tgttacagag gtcggggtct tctcgccaaa agcagttgct
    36241 agagactttt tgatggtcgg tgatgtcggt tatatcacag caagtatcaa aactgtccaa
    36301 gatacacgag taggggatac agtaacgtta gcagacaatc ctgccgctga agctttacca
    36361 ggttaccgaa aaatgaatcc gatggtttat tgtggtcttt atccaattga tacttctcgt
    36421 tacaacgatt tgcgggaagc tttagaaaaa ctgcaattga atgatgctgc tttacaattc
    36481 gaaccagaaa cctctcaagc attaggtttt gggttccgct gtggattcct cggacttctt
    36541 catatggatg tcgtccaaga acgcttggaa cgggaattca atctagaatt gatcacgact
    36601 gcaccatccg ttatttacca tgttaataaa acggatggta cgactgctac agtagataac
    36661 ccggcagatt ttcctgaacc tgtaacgatt caggatgtag aagaaccatt cgtcaaagca
    36721 cagatcatgg tcccaaatga ttttgtcggt gcagtaatgg aactttctca acgaaaacgg
    36781 ggagaattca ttacgatgga ttatttagat gattaccgag taaatgtcgt ctataatatt
    36841 ccgctttctg aaattgtctt tgactttttc gacaaattga aatcaagcac gaaaggctat
    36901 gcctcattgg attatgaaat gtctggttat caaaaaagca agttagtgaa gatggacatc
    36961 ttgctgaatg gagaaaaagt cgatgcatta agctttatcg ttcaccgaga ctttgcctat
    37021 gaacgtggaa aagcaatcgt tgaaaaactg aaaaaactaa tcccacgcca acaatttgag
    37081 gtgccaatcc aagcagctat tggacaaaaa atcgttgccc gttcagacat caaagccttg
    37141 cgtaaaaacg tcttggctaa atgttatggt ggagatgttt ctcgtaaacg taaactctta
    37201 gagaaacaaa aagaagggaa gaagcggatg aaacaaatcg gctccgtcga agttccgcaa
    37261 gaagccttca tggccgttct gaaaatggac gaggacgaac cgaagaaata gcaagggttt
    37321 gtttgaaaac agtgtaaaaa ataaaccatg tttacatgga tttgccaccg gtttgccacc
    37381 ggtg
//
LOCUS       DAIGSZ010000023        36569 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.023, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000023 DAIGSZ010000000
VERSION     DAIGSZ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.023"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="NOB31_001219"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="NOB31_001219"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HCI0973438.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="NOB31_001220"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="NOB31_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HCI0973439.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVDCREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="NOB31_001221"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="NOB31_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HCI0973440.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="NOB31_001222"
     CDS             complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="NOB31_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HCI0973441.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="NOB31_001223"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="NOB31_001223"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HCI0973442.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="NOB31_001224"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="NOB31_001224"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HCI0973443.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="NOB31_001225"
     CDS             complement(8053..8523)
                     /locus_tag="NOB31_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HCI0973444.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="NOB31_001226"
     CDS             complement(8569..8994)
                     /locus_tag="NOB31_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HCI0973445.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="NOB31_001227"
     CDS             complement(9061..9330)
                     /locus_tag="NOB31_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HCI0973446.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="NOB31_001228"
     CDS             complement(9341..10936)
                     /locus_tag="NOB31_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI0973447.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="NOB31_001229"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="NOB31_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HCI0973448.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="NOB31_001230"
     CDS             complement(14489..15049)
                     /locus_tag="NOB31_001230"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HCI0973449.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="NOB31_001231"
     CDS             15402..16376
                     /locus_tag="NOB31_001231"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCI0973450.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="NOB31_001232"
     CDS             16546..17946
                     /locus_tag="NOB31_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HCI0973451.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="NOB31_001233"
     CDS             complement(18024..18746)
                     /locus_tag="NOB31_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0973452.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="NOB31_001234"
     CDS             complement(18825..19331)
                     /locus_tag="NOB31_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCI0973453.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="NOB31_001235"
     CDS             19454..21253
                     /locus_tag="NOB31_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HCI0973454.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="NOB31_001236"
     CDS             complement(21321..22895)
                     /locus_tag="NOB31_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCI0973455.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="NOB31_001237"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="NOB31_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HCI0973456.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="NOB31_001238"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="NOB31_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HCI0973457.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="NOB31_001239"
     CDS             complement(24672..25310)
                     /locus_tag="NOB31_001239"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HCI0973458.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="NOB31_001240"
     CDS             complement(25311..25961)
                     /locus_tag="NOB31_001240"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCI0973459.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="NOB31_001241"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="NOB31_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HCI0973460.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="NOB31_001242"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="NOB31_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HCI0973461.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="NOB31_001243"
     CDS             complement(29104..29844)
                     /locus_tag="NOB31_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HCI0973462.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="NOB31_001244"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="NOB31_001244"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HCI0973463.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="NOB31_001245"
     CDS             complement(31215..32153)
                     /locus_tag="NOB31_001245"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HCI0973464.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="NOB31_001246"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="NOB31_001246"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCI0973465.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="NOB31_001247"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="NOB31_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HCI0973466.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="NOB31_001248"
     CDS             complement(35313..35618)
                     /locus_tag="NOB31_001248"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI0973467.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="NOB31_001249"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="NOB31_001249"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HCI0973468.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7989 c         6705 g        11989 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaatc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatcg cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gcaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ccagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttcgtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc taattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gatatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatac
//
LOCUS       DAIGSZ010000024        34958 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.024, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000024 DAIGSZ010000000
VERSION     DAIGSZ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.024"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            153..1859
                     /gene="efbA"
                     /locus_tag="NOB31_001250"
     CDS             153..1859
                     /gene="efbA"
                     /locus_tag="NOB31_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HCI0973469.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2017..2919)
                     /locus_tag="NOB31_001251"
     CDS             complement(2017..2919)
                     /locus_tag="NOB31_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0973470.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2916..3608)
                     /locus_tag="NOB31_001252"
     CDS             complement(2916..3608)
                     /locus_tag="NOB31_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HCI0973471.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3651..4292)
                     /locus_tag="NOB31_001253"
     CDS             complement(3651..4292)
                     /locus_tag="NOB31_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0973472.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4330..4644)
                     /locus_tag="NOB31_001254"
     CDS             complement(4330..4644)
                     /locus_tag="NOB31_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973473.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4632..5984)
                     /locus_tag="NOB31_001255"
                     /pseudo
     CDS             complement(4632..5984)
                     /locus_tag="NOB31_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372436.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
     gene            complement(5981..6913)
                     /locus_tag="NOB31_001256"
     CDS             complement(5981..6913)
                     /locus_tag="NOB31_001256"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HCI0973474.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6910..7686)
                     /locus_tag="NOB31_001257"
     CDS             complement(6910..7686)
                     /locus_tag="NOB31_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HCI0973475.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7740..10925)
                     /gene="carB"
                     /locus_tag="NOB31_001258"
     CDS             complement(7740..10925)
                     /gene="carB"
                     /locus_tag="NOB31_001258"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HCI0973476.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10930..12006)
                     /gene="carA"
                     /locus_tag="NOB31_001259"
     CDS             complement(10930..12006)
                     /gene="carA"
                     /locus_tag="NOB31_001259"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HCI0973477.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12011..13291)
                     /locus_tag="NOB31_001260"
     CDS             complement(12011..13291)
                     /locus_tag="NOB31_001260"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HCI0973478.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13310..14236)
                     /locus_tag="NOB31_001261"
     CDS             complement(13310..14236)
                     /locus_tag="NOB31_001261"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HCI0973479.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14249..15532)
                     /locus_tag="NOB31_001262"
     CDS             complement(14249..15532)
                     /locus_tag="NOB31_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HCI0973480.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="NOB31_001263"
     CDS             complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="NOB31_001263"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HCI0973481.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16320..17231)
                     /locus_tag="NOB31_001264"
     CDS             complement(16320..17231)
                     /locus_tag="NOB31_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI0973482.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17228..17692)
                     /locus_tag="NOB31_001265"
     CDS             complement(17228..17692)
                     /locus_tag="NOB31_001265"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HCI0973483.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17697..18395)
                     /locus_tag="NOB31_001266"
     CDS             complement(17697..18395)
                     /locus_tag="NOB31_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0973484.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18382..18768)
                     /locus_tag="NOB31_001267"
     CDS             complement(18382..18768)
                     /locus_tag="NOB31_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973485.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18915..20585)
                     /locus_tag="NOB31_001268"
     CDS             complement(18915..20585)
                     /locus_tag="NOB31_001268"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HCI0973486.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20768..21001
                     /locus_tag="NOB31_001269"
     CDS             20768..21001
                     /locus_tag="NOB31_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HCI0973487.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21100..21531)
                     /locus_tag="NOB31_001270"
     CDS             complement(21100..21531)
                     /locus_tag="NOB31_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HCI0973488.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21610..22023
                     /locus_tag="NOB31_001271"
     CDS             21610..22023
                     /locus_tag="NOB31_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HCI0973489.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22061..23209)
                     /locus_tag="NOB31_001272"
     CDS             complement(22061..23209)
                     /locus_tag="NOB31_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI0973490.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23331..23927)
                     /locus_tag="NOB31_001273"
     CDS             complement(23331..23927)
                     /locus_tag="NOB31_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0973491.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="NOB31_001274"
     CDS             complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="NOB31_001274"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HCI0973492.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27157..27588
                     /locus_tag="NOB31_001275"
     CDS             27157..27588
                     /locus_tag="NOB31_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0973493.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27633..28982)
                     /locus_tag="NOB31_001276"
     CDS             complement(27633..28982)
                     /locus_tag="NOB31_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI0973494.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29052..30215)
                     /locus_tag="NOB31_001277"
     CDS             complement(29052..30215)
                     /locus_tag="NOB31_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCI0973495.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30344..30667
                     /locus_tag="NOB31_001278"
     CDS             30344..30667
                     /locus_tag="NOB31_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973496.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30850..32199)
                     /locus_tag="NOB31_001279"
     CDS             complement(30850..32199)
                     /locus_tag="NOB31_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0973497.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32268..33221)
                     /locus_tag="NOB31_001280"
     CDS             complement(32268..33221)
                     /locus_tag="NOB31_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HCI0973498.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33323..34513)
                     /locus_tag="NOB31_001281"
     CDS             complement(33323..34513)
                     /locus_tag="NOB31_001281"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HCI0973499.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9950 a         7640 c         6120 g        11248 t
ORIGIN      
        1 taaaaatttg gatttcaacg atagaaacac tgttttttat gtaattagtc caagattttt
       61 ctagactttt gctttactat tcggccaaat tggtttttct tctttttttc gttataatga
      121 atatacttat gaaaagaaat gaggaatgaa ccatgtcctt tgatggtgta tttacccacg
      181 cgatggtcaa cgaattgcgt gaaacgttac tatctggccg gatctcgaaa atccatcagc
      241 cttatgaaaa tgaaatcgtg ctggtgattc gttcacgcgg caaaaaccat cgattattat
      301 tatctgcgca cccaagttat gctcgtgtac agattaccca aatcgattat cagaatcctg
      361 ataatccgcc taacttcgtg atgatgcttc gaaaatattt ggatggcgct attttagaag
      421 acatcgaaca aatcgaaaat gatcgagtga tccatttcca ctttgctaaa cgaaacgagt
      481 tgggtgatct acaaaatatc atattgatcg ttgaattaat gggacgtcat agtacgatcg
      541 tcttagttaa tcgagaaact ggaaaaatac tggatgcgat caaacacatt ggaagctctc
      601 aaaacactta tcgttctttg cttcctggtg tagaatatgt tgctccgcca aaacaagagg
      661 tcttgaaccc atttagctcc gagaaagaaa aaatctttca gcggctttcc caaactgaac
      721 tagatccaaa agcaatccaa cgtcagtttc agggaatcgg tttcgatatc gctcaagagc
      781 tgaccaaaag attactggaa cgtcctaatg aaaagatggt tgtatgggac gaatttttct
      841 cagccatcag ccatcagcct attcctactt tttacgaaac ggaaaataaa gattttttca
      901 caccgattgc ttatcaggta ttgtccgaac aggcatctgc tgtaacagct tatccaacac
      961 tcagtcaatt attagatagc tattatcacg aaaaagcaga gaaagatcgg gcaaaacaac
     1021 aaggcggaga actgattcga aaaatcgaaa atgaactaaa acgaaataaa aataaattga
     1081 aaaaacgtga acaaacactc aaagaatccg aaaacgctga gaattaccgt agaaatggcg
     1141 aactacttac tacttttctg acacaagtac cacgcggcgc aaaagaagtt gttttaccta
     1201 attattatga agaagatcgg ccaatcaaaa tagcactaga tccggcattg acaccaaatc
     1261 aaaatgcaca gaaatatttc catcgatacc aaaagctgaa gaacgctgtt aagctgattg
     1321 gcgaacaaat ccaagaagcc aaagatgaaa tccaatatct tgaatctgtc ttatctcaac
     1381 tggaaattgc cggcccaatg gatatcgaag caattaaaga agaattgact tcagaaggat
     1441 acctgaaaaa gaagaactta aaaaaacaaa aacgtaagaa accatctcag cctgatcaat
     1501 acttttcttc tgacggaacg ctcattcttg ttggtaaaaa caatcttcaa aatgaccagc
     1561 tgacaatgaa gacagctaaa aaaaccgact attggcttca tgcaaaaaat atacccggtt
     1621 cgcacgtcat cattaaaagt gacaagccct cagatgaaac aattacagaa gctgccgagt
     1681 tagctgccta tttttcaaaa taccgatact ctgcccaagt gccggttgat cttgtacagg
     1741 taaagcatat ccgaaaacca aatggcgcca agcctggtta tgttatttat gaaaaccaaa
     1801 agacgattat cgtgacacca gaagaagaaa aaattacagc tatgaaacaa aacaggtaat
     1861 caatgagtgt ttctagaatc atatttgcgt actttcccac aacagcaatt agttataaat
     1921 tgtttgctac aaaaagagga gttgtgacaa aattctgtca caacccctct tttttgatca
     1981 acggtgttca ataaacagcg ttctcatctg cttttcttag ctctgctggt ccagtaaccg
     2041 agtaagctct ttgataaatc tttgagcgat ttcactgagc ggacgtttcg ccgaataaat
     2101 gatataaaat tcatttagtt cgccttctgc caaagggatt aaccgcaagt gctcgcgaat
     2161 ccctccaatc acaataccag atcctgaagc gtaagcatca gtttcaagaa cgatattcat
     2221 caaagtacct cgatcactcg tataaatcac tgtttcttga tcagggatct cgataaggtc
     2281 ttcataaaaa tacgggaaat tatttccatc ctgtgtaaaa cgaacttgag gataagataa
     2341 caattcttct ttggtgatct ctgcgtgttc agctaatgga tgtccttgcc ttaaaaaaat
     2401 atgcgttttg aattttccaa tgctgcggcc acttagctct ccttgttgta aatatcttct
     2461 gataccagct tgattatgct cattcatata aataatgccg atctcactgt gctgctcttt
     2521 gacttcttcg atcactctcg ctgttgtcgt ctccatgatc cgaaattgtt tgatctcgtc
     2581 tttgaattcc tcgagtagct gtgcggtcaa aggacctaag aaatcataat gctgggcagc
     2641 gatcgaaaaa ttgtctctct tttcactcgt tagatagtga gtttctaatg tatcaagctg
     2701 gaccaatatt ttctcggcac gatttaagaa gtcttgccct tcttctgtta aatatgcccc
     2761 tcgattcgtt cgagtaaaca gcgtgatccc taactcggtt tctaattctt tgataccagc
     2821 tgaaagactt ggctgggaga caaacatttt ctttgccgct tctctgaaac taccattgtt
     2881 tgctacagcg accacgtatt tcatctgctg aatattcatt gctcaaactc ctcgaaataa
     2941 taaatttctc ttccattcaa gggctggatt ggtcggttgt tcggtcgagc atactgacca
     3001 tcgaagggga gaagaaactc ttggttcagt tttcctacat gatccattac aaaccattgg
     3061 attggcccgc tggtaggcgg agttgtcaat gagccaatat aatggaaatg gcttttttgc
     3121 tccggaaaga acacatccgg atttacccaa tgctcatgtt tttctaagtt ccaactttcc
     3181 ccattttctt gattatacag ccaaccttcc tgtaccatta gctggtacat gacacccaca
     3241 actagattct cttttttgct gttcatatga acaaaatgaa attcaatatc ttcctgtttt
     3301 ccgttgatga tatgttcaga aggcaagtgg aaatgaatat ctgtcaaata atagcgttct
     3361 ttcttgaact ctacataact gagttggtca aaaggtacta aatgaatcgt gtttttgaat
     3421 tccttgtcag taaaccgttg cttttgataa tgaaaggaaa gcgtgtctcc ttctattttg
     3481 gtttcttccc ccttggtcaa atgaataggc gactgcaatg gaaattccgc acctctcgca
     3541 aaccaatcac ataaactcgc ccaattttcc ggacctttgt ctccagaata gccccattcg
     3601 acatccatat tctttttcaa ctatacttcc ccctgcatct catatcattt ttatttttct
     3661 tctttcttta caatcgttga gacggtttct aaaaacgcct cttttccata aaattcctgg
     3721 ttcaatagtt ccggaaatat ctctttaaag aaatactgaa cagaaggccg atgttcaaag
     3781 cttttaatcg tagtcactgc ctcaatgaac atctccttat aaactttttc cgggttattt
     3841 ttgatgattt catcaaaaga ttcataaaga aggtcaacct tatctgaaat ggctaatagt
     3901 tctccttcta cggtttcatc ttttccttcg aacaaccgac ggcgataaac ttcttggaac
     3961 tcagctggaa tctcttggtt gatgaattcg tccgtcatct tttcttcaac tgtttgcagc
     4021 atccctctta actctttgct tgcgtatttc accggcgttt tgatatcacc aataaaacgc
     4081 tctgtgtagt catgattcaa tgatttttca tagagcagtt tccaatcgat cggttgtcca
     4141 ttcgcttctt caatgtctcc tagaacttgc gcaatagatg ctacacgata cgaatgtgct
     4201 gcaactgtat gctctgtata tttaaaaaat ccaggtgccc ttgtgatcgt ctctaaattg
     4261 ttcaatccta aaataaattc attcaacccc ataaaagtta cctccctttg agatttcttt
     4321 ttccgaatat catatcatta aataactgat attcgcaaca tttccgctct ttaccatttt
     4381 tgaaacagct cccttaccaa aaaatagaga aaatctatat ataatagaaa aaagagaaga
     4441 gattattctc ttctttctgc taaccagtct tagaaaaatg aattttaaaa aaatcaaaaa
     4501 ctgatcacga tagaagtttc ttttcatacc tgatgaaaag atgcttctcg caatcagttt
     4561 ttggattttt gctattccaa ttgatgattc tggagacaca aatcggattt ctctatcttc
     4621 atcaagcgcg cttaaatctg ccaattttca ggatcttttt tccattcttt tagcagagtt
     4681 aattcttgct catcgatata acgatcttct aaagctgctt caatcaatac agaataattg
     4741 gtcaacgtca taagagggat ttcggctttt tcgaaatttg cttttccttt tggcaactca
     4801 tacgtaaaga tagccgcaac accaaggata tccgcacctt ctctttttgc tgcttcagct
     4861 gcttccaaga cacttccgcc tgtagaaatc aaatcctcga tcacaaccat cttctgacct
     4921 tcaaatatac gtccttcgat ttggttacct ttcccatgat ctttcgcctt acttcgaata
     4981 tagaccattg gcaaatccag tatttccgct acccatgcgg catgagggat tcctgctgtt
     5041 gcagttccag caatcacttg tacttcaggg taagcttctt tgattttgct tgctaatcct
     5101 tttgcgatct cttttcggac ttttggatag ctcatcgtga ttcggttatc acagtaaatt
     5161 gggcttttga ttccacttgc ccatgtaaaa ggattacttg gatttaaaaa tactgcttca
     5221 atttctaata agtcttttgc gatactttgt tcaacattca ttttaggtta gctccattct
     5281 gtttgaatcg tttgatatgc tttataagga ttagttgact gagtgattgg tcgacctata
     5341 acgataaaag ttgagccgat cttttttgcc tgagaaggtg tgactactct tgtctgatct
     5401 cctgcgactg ttccttctgg tcttataccc ggagttaagc aaacaaattc gtctcctgcc
     5461 atttctttga tcgcttctac ttcccaagca gaagaaacca caccatctaa tcctgctttt
     5521 ttggcacagc tagcataatg gatcacactt ttttctaaag aaacttcgat tagttgatcg
     5581 gcatgcattt cttcttcact tgtagaagta agctgagtga tagctagaag tagcggacgt
     5641 tttccacctt ctggagtccc ctcttctaat cctcgcattg ccgcctccat catacgaata
     5701 ccgccagcgg catgaacaca ggtgagatca acaccaagct ttgccaatcc ccgcattgct
     5761 ttttcgaccg tattcggaat atcgtgaagt ttcagatcta aaaatacatt atgaccagcc
     5821 tcttttagat aacgtacgat ttcaggtcct tcttggtaga acaattccat tccgattttc
     5881 acaaacaatt tttcttcttt cgggaaaaat cgaagaaagt cttctacctc ttgcctagtt
     5941 gaaaaatcta atgcaataat tggtcgttgg tctagttgat tcatcgttca cgttcctctc
     6001 tcacttcttt gattaatctt tccagcgatt cgatgcctag ttcgctcatt cgcacaggga
     6061 gctctttaat tagtttagga cagatatacg gatcggtgaa attcgcggtc cctatagcta
     6121 cagcacttgc tccagccata aacatctcaa gaacatcatc cactgtctgc acgccgccca
     6181 tcccaatgat tggaaggctg gatatacttg ctacttggtg aatcaaacga atagcgacag
     6241 gcttgattgc tggtccggag agtccacctg tttgattggc taaaatcggt tttcttgtct
     6301 taaggtcaat ccgcatacca agaagagtat tgatcatcgt aaacccatct gcccctccag
     6361 cttcgattgc ctgagcgatt ggaacgatgt ctgttacatt tggggacaat ttgacataga
     6421 caggaacaga agaaactttc tttactgctt gtgttaattg aaaagcaaca tcagaatctg
     6481 ttccaaaagc aattccgcca tgtttgacat ttgggcaaga aatgttcagc tcgattgctt
     6541 tcacatttgg tgcttcgcca attttgctac aaacttctac atagtcttct tcacaagcac
     6601 cagcaacatt tgcgatgatg ggtaactcat tgtactcctc taattctgga agaagtttat
     6661 gcataacaac gtctagacca ggattttgca aaccaattgc attcaacatg ccagatggtg
     6721 tttccgccac tcttggcgtg ggattgccaa agcgggcatt tggagtcgtt gccttgacca
     6781 tgatcgatcc aagctgattc aaatcatagt attttccgta ttctttgcca aaaccgaaac
     6841 agccgcttgc cggcatgata ggatttttta attctaggcc aggaagtttg accgctaaag
     6901 gattctcatt catataatta cctctcctat tttaaaaatc ggtccttcgt cacaaacttt
     6961 cacacttttt gttcctgttt catcttccgg cgtatgacaa acgcaagcat agcaagcccc
     7021 tatcccacat gccatgcggg attctaatga taactggaca ttttgatgcg aagaaaacag
     7081 ctgttccact gtcttcaata acccgtttga accacatgca aaaacagctg taggttccgt
     7141 cttcgttcct aacaataaat taccgacatt tccgtgcata ccgtatgttc catcgtcagt
     7201 agcgattctt gtttctccta gacgattaaa ttctttttca taataaacga cttcatgtgt
     7261 ggcaaaacct aaaaaatgcg ttggcttaat tcctttttcg actaactgtt ttgataactc
     7321 atatagagga gggacaccga ttcctccacc gattataaat acttcgtctc ctgtatgaag
     7381 attggacaaa tcaaaaccat tgcctaaagg acccatgaca tctaaatggt ctccggcaga
     7441 aagagtagag aagactctag tcccctcacc ttccacccga taaatgatac ggcaagtatt
     7501 tgtttcgtgg tcgatatgat tcaagctaat cggtcggcgt aatagcaagt ctgcacgcgg
     7561 cacgagaata tgcaagaact gtcctggttg ctgcatttct tttactagat cacctttcaa
     7621 tgtcatttca aaaatctttg gtgccagctg tttttgctga acgatttcca tcatttcttg
     7681 tttcatctgt cccctcctgc aacggttttt cgtctttttg tcttaacatg tgctcgccgt
     7741 taaatagggt tagttgaaaa agcacgggat tccatcactc gaacgatcgc atctgctgtg
     7801 tctaaagaag taaacaatgg aataccatgt tcaactgctt ctcttcggat gatgaaaccg
     7861 tctttagaag catttccccg atctttatca atcgtattga caaccacttg tgttttacca
     7921 tctcttatta agtcgactac atttttttct gctgcttcct cagaaatttt cgctactgtt
     7981 tcaacgacca gaccattttt ttcgaaataa gcagctgtat gtttcgttcc tatcagacta
     8041 tagccaattt ctgtaaaacg tttagctaat tctagtgctt cttcttttgt ttcgtccgca
     8101 atcgtaaata atacggctcc atattcaggc aagtgtaatc cagaagcttc gaatgccttg
     8161 tacaaagctt tgtctaattg tctgtcagat cccattactt ctccagtcga tttcatttca
     8221 ggccctaagt aagtatcaac tttctgcaat ttcgtaaaag aaaagacagg tgctttaaca
     8281 tgaacttctt ttgtttctgg ataaagtccg ttttcataac caagtgtctt tagtttctct
     8341 cccaaaatag ctttcgtcgc aatttgtgcc attggaattc ctgtcacctt acttaagaat
     8401 ggaacagtcc gacttgctcg aggattgact tcgatcacat aaacctcatt ttcatggatg
     8461 acaaactgga tattcatcat cccgacacaa ttcaaaccta atgctaagcg gatcgtgtaa
     8521 tcttcgatcg ttttcttgat cgattcagat aatgtttgag gtggatacac agccattgaa
     8581 tcccctgaat ggacaccagc acgctcaata tgctccatga tccctgggat gagtactgtt
     8641 tcaccgtcac aaatcgcatc cacttcgcat tcaccaccaa gcaagtaacg gtccactagt
     8701 actggatgtt ctggagatgc tttcacagca tgttccatgt aatcttctaa atctcgctgg
     8761 ttttcaacga tttccatcgc acgtccgcct aatacatagc ttggacgaac aagaactgga
     8821 taaccaattc tcgaagcgat aaccacggct tcttctttac ttgtagcagt atcccctaaa
     8881 ggttgaggaa tatccaactc tttcagcgct tgctcgaata aatcacgatt ttccgcacga
     8941 tccaagtctt cgatcgttgt ccctaagatt tttacaccag cagcagtcaa aggttcggct
     9001 aagttgattg ctgtctgacc accaaattga acgattactc ctatcggctg ttctagctcg
     9061 atcacattca tcacatcttc gaaggtcaat ggctcaaaat ataatttatc cgaaatagaa
     9121 aagtcagtcg aaactgtttc aggattgctg ttcatgatga ttgcttcgta tcctgcctgc
     9181 tggattgctt tgacagaatg cacagtcgca tagtcaaatt caaccccttg tccgatacgg
     9241 ataggaccag atcccagtac tagaattgag ggcttttctg atcgtgaact ttcattttca
     9301 tattcatagg aactataaaa ataaggtgtt tttgattcga attccgctgc acaagtgtca
     9361 accatcttat atacaggaat caaatcattt tcttttctca tctggcgaac ggcttcttcg
     9421 tttatttccc acagctccgc cacttttttg tctgtaaaac cgttttgttt cgctgttttc
     9481 aatatcttgt catccaacgg ctgctgtttc aactgctgtt cgatttctac gatatgcaac
     9541 agtttatcta aaaagaataa atcgattttt gtcaaatccg ctaattcttc tatggtgtac
     9601 cctcttctaa tagcttcagc tacataaaac aggcgatcat cttgtgctcg aaccactttt
     9661 tggattaggt catcgtccgt gatgtctgcc aactcaggaa gttcgatatg gtgtgtaccg
     9721 atttctaaag aacgcacagc tttcaataaa gactcttcga tattccgacc gatagccatc
     9781 acttcaccag ttgctttcat ctgcgtgcct aaaagccgtt ctccgttttc aaacttatca
     9841 aacggccagc gaggaatttt agctacaaca taatctaatg caggttcaaa ttctgcaaaa
     9901 gtcgttcctg taacaggatt tttcatttcg tctaatgtta atccaagcgc tattttagca
     9961 gctagcttag cgatcggata gccagtcgcc ttacttgcta acgcagatga acgagaaaca
    10021 cgcggattga cttcaatcac ataataatta aaactatgtg gatcaagagc gagttggaca
    10081 ttacagcctc cctcgatctt aagtgctcga ataatcgaaa gagaagcatc acgaagcatt
    10141 tgatattcat ggtcagacaa tgtttgacta ggggcaaata cgatagaatc acctgtatgg
    10201 atacccaccg ggtcaaaatt ttccatattg cagacaacga ttgcattatc agccgaatct
    10261 ctcatcactt catattcaat ttctttaaaa cctgcaatac ttcgttcaat caaacattgg
    10321 gtagcggggg aaagacttaa tccattttct gatacgatac gtaattcttc ttcattttca
    10381 cacatacctc caccagttcc gcctaaagta aaggctggac gaacgatgac aggatagccg
    10441 attttatttg caaaatctac agcttcttct actgtattga cgatttcaga ctcggggatt
    10501 ggctgattca attctttcat caactgtttg aatagatcac gatcttctgc ttgatcgatc
    10561 gcagaaagct ttgttcctag aagttctatg ttcaattctt ctaaaatacc tgatgctgcc
    10621 agctccattg ccatattgag gcctgtctgt ccgcctaaag ttggaaggag agcatctgga
    10681 cgctcttttc gaagaatcct tgatacaaat tcaagtgtga tcggttcgat atatacttga
    10741 tctgccactt ctttatccgt catgatcgtc gcaggattag aatttactaa aaccacttca
    10801 tatccttctt cttttaaggc aaggcaggct tgtgttcctg cgtagtcaaa ttctgcggct
    10861 tgaccaatga tgatcggacc agatccaatc accataattt tcttgatatc tgtacgtttc
    10921 ggcatctgtt tactgctcct ttcctgcgtc catcatttcc ataaattcat caaataaatg
    10981 tagtgcatca tgcggaccag gggcagcatc tggatgaaac tgcacactga aagcgggata
    11041 atctctgtgt ttgactcctt ctactgttcc gtcatttact tctacatgag ttacgatgag
    11101 tttttctgga tcaatcgtgg cttcatcgac tgcatagcca tgattttgag aagtaaaatc
    11161 aattcttccg gtcgctactt ctcgtaccgg gtgatttaat cctcgatgtc cgaatttcat
    11221 tttataggta tctgcaccgt tggctaaagc aaataactgg tgaccgagac aaataccaaa
    11281 aatcggtact tttccttgga tttttttgat catttcgatt gcttctggca catcttttgg
    11341 atcaccaggt ccattcgtca gcatgactcc gtctggtgat agcgctaaaa tcgtctcggc
    11401 atctgtgtta tagggaagta ctgtgaggtt acagtttctt ttactcaatt ctcgtaaaat
    11461 actatgtttc aagccgaagt caatgacaat gactttccga cctgttcctg gacttggata
    11521 aggtttgtta gttgagactt gctgcacttg attggttgct agaacggttg ctttcagctg
    11581 atcaaatgca tgttcgaagg aatctccagc atcaactata ctagctttca tcgttccgac
    11641 ttcacggatt ttgcgagtaa gggcgcgcgt atcgatacct gatattccag gaattccttt
    11701 ttgtttcaaa aatgaatcta gcgtcatttg gtttcgccag tttgaagcta cacgtgcatg
    11761 ttcttttact actactcctt tgcatgttgg agaaatcgat tcataatcat ctctatttac
    11821 cccataatta cccaccatag gataggtaaa tgtaatgatt tgaccgttaa aactttgatc
    11881 agtgatagtt tcttgataac cagtcatact tgttgtaaaa acgatttctc cgaagacact
    11941 agcatctgca ccaaaagcct ttccttcgaa aactgttcca tcttctaata taagcaaacg
    12001 ttccatactt ttattctccc ttctgccaca caagttttcc gttgacaaaa gtcatttgtg
    12061 tttcgccttt tactttccag ccgataaaag gtgtattctc cccttttgat aaaaagtctt
    12121 ctttatcgat cgtgcaagtt tgtgtaatat caaaaactgc tacatcagcg ggggcaccaa
    12181 ccgttagcgt tcctgcattc aaaccaaaaa tctcagccgg tttaactgcc aaccaattga
    12241 tcacttgttc caacgtgaat cgaccagttt ctacaaaatg agtatagatc agttgaaacg
    12301 ctgtttcgct tcctacgata ccaaatggtg atttcatgaa actttggctt ttttcttcta
    12361 atccatgggg ggcatggtct gtagcgatgc aatcgatcgt accgtcaagc aagccttcga
    12421 tcaaagcttc tctgtcctcc cgtcctctta gcggcgggtt cattttccaa aagccgaaat
    12481 cttcgggaat atcttcgtcg atcaaaataa gatgatgggg tgaaacttct gctgttacgt
    12541 ggattcctgc tttttttgcg tctctgatta cacggacact ttctttagta gaaacatggc
    12601 aaacatggta atgaacacca gttgcttcag ctagcaacag atctctagca atttgagaag
    12661 actcggttac gcttaagatc ccgggaagac caagttcttc tgccttcttg ccagcgtgca
    12721 taacgccgcc aaataataaa gattcatctt ctgtatgggc tactagggct ttattgtttt
    12781 ttgcagcttc tttcatagcc agatacatcg tcccagctgt ttggacacct acaccgtcat
    12841 ttgtgaaagc aaaagcacct tcttcaatca gtgcttcttg atcaactaat ttctcacttc
    12901 gcagattttc tgtgattggc gcatactgca ataccttcac aactgcatct tttctaatga
    12961 tgtcatatac ttgtctcagc ttttctgccg tatcaggtac aggatttaaa ttcggcatcg
    13021 cgcatacagt agtgaaaccg ccacgagcag ctgagcgagt cccagcttcg atcgtctcct
    13081 tgtatgtaaa tcctggctct ctcaaatgaa catggacgtc cactaaacca ggtgtgatca
    13141 attgtccctt tgcatcaaac acttcatcaa attcggcttc tgagaatcct gtaccgattg
    13201 ctttgattcg cccatcttct atccaaattt ctgctggtgt cgtcatattt tttcgtgtat
    13261 tgatctgacc gtttttaatg agtgttttca ttttttcatc ctcctataat tacgcttttc
    13321 catttagcac tgcttctaag attgccattc tgacgaatac tccattgctc atttgctgaa
    13381 cgatccgcga ctgtaatcct tccactaatg aatcagctaa ttctacatca cggttaactg
    13441 gtgctgggtg cataatgatt gcatgttttt gcaacttctt cgcacgctca actgttaacc
    13501 catgttcctg atggtagcct tcttttgaga aactttcttt tccatcatgg cgttcgtgtt
    13561 gcacccgaag catcatcatg acatcaactt gatctagtag ttcatccaat ggcatataat
    13621 gtccgtacac ttcgaattca tcgtcgtacc attctctagg acctgagaag aatacttgtg
    13681 cgcctagacg ttttaacatc tgcatattgg atttagctac gcgagagtga gtgatatcac
    13741 ctacgatggc aactttcaga ccttcaaaat gaccaaattc ttcataaatg gtcatcaaat
    13801 caagcaagca ttgggttgga tgctgtccgc ttccgtctcc tccattgata atcgaacact
    13861 ggattgtttt actttgtatc agttcgtcat aatagttctc atcaccatga cggataaccg
    13921 ctacgtctac gcctaatgct gacatcgtca gtactgtatc gtatagtgtt tccccttttt
    13981 ggacagagct tgtgcttgct tcaaattcaa tcacttctag ccctagtttt ttctccgcta
    14041 catcgaagct tttatgtgtg cgagtactat tttcgaaaaa gaggtttgta gcaaagtact
    14101 ggcgcttttg cggagtccaa ttagcacctt gcttgaattc ctgccctctg cggatcaagc
    14161 ccataacttc ttgatcagta agtgcctcaa cggtcaataa atgctttaag ctgatacgtt
    14221 ctgatttgat gatcataatg tttcctcctt agttttcttc gcttcgtgaa gtttctggta
    14281 agataagatt taaaatgatg ccaagtacag ttgctaatgc cattgccgac aatgtaaatg
    14341 tgcctacttc aaagacgagt ccgccaattc ctactactaa gataactgaa gcaatcaaca
    14401 gatttttctt tttatcaaaa tcgattttgt tctcgattaa aatcttcatt ccacttgcgg
    14461 caattactcc aaataagata aaactgattc ctgagatgac tggtccaggg atacttaaaa
    14521 tcaaagcgct taattttcct acgaatccta aaatgactgc aaatactgca gctccaccga
    14581 tcacaaacac gctatggaca cgtgtgatag ccagaacacc aatgttttca ccgtaacttg
    14641 ttacaggagg acctccgaca aaggctgcca cgatttgtgc taatccatca cctgtcaacg
    14701 tcttatgaag acccggttct tcaaagaaat tacgtttagt tagtttattc aataccataa
    14761 gatggccgat atgctctgtc atcgtcacaa aagcgatggg tgccattgtt gtgattgctc
    14821 caagatatag ctttggttca tattgtacaa agggaatctc aaagttagga acagcaaacc
    14881 aggcagcgtc tacgattggc ttagtatcca cgattccaaa cagcaaggct acgatgtatc
    14941 cgctaataat acctagtaaa atcggaatca atccgagaaa acctcttagc cacatgttga
    15001 agaaaattgt taatcctaat gtgatcagcg ctacagcaat atacttgaaa tcatacgtgc
    15061 cctgattata catagcattt gttgctgcat ttgccgcaag tcccaacccg ataaccatga
    15121 tgactggacc gacgacgatt ggaggcaaga ttttatccag ccatgctgaa ccgatctttt
    15181 tgatgatcag cgcaacaatc aaatagacta atccagttgt gactgctcct tgtgcaatcg
    15241 ctggataacc atctgttttc atcaaaagct gcatcgctgc aatgaaagcg aagctgcttc
    15301 ctaagtacgc aggtatcttt cctttagtag taaataagta caccaatgta cctagtcctg
    15361 aactgactag cgcaatacct ggatcgatac ctactaagat ggggactaac acggttgctc
    15421 cgaacatcgt gaacaagtgt tgtaaactta atcctaccca atgtcctggg gttgggcgat
    15481 cgtggatatc taacaccacg tcatcattat gaaatccttt tttctccgac atgtttctct
    15541 ctcctctaat cttcctcttt caaaatcatg atgcgatctt gtccatcaag ctcttgcatc
    15601 tctactaaaa tctcttccgc ccgagatgtt ggaatgttct tcccaacata atctgcacgg
    15661 attggcaatt ctcgatgccc acgatcgacc aggactgcta atgaaatttt tcttggtctg
    15721 ccaaaatcca ttactgcgtc cattgctgct cgaatcgttc gtcctgtata caaaacatca
    15781 tcaatcaaaa taacttcttt tccttctaag gaaactggga tgtcagaaga atgaagttcc
    15841 ggttcttctg gattttcttt tttgtcatct cggtataaag tgatatccag ttctcctaca
    15901 ggaatatcga tatcttctag ctgcttcagg cgttcggcaa ttcttgatgc aatgtagatt
    15961 cctcgtgttt tgatacctac caatacgata tcttggatac tatggtttct ctcgataatc
    16021 tcataagtaa ttcgagtcaa tgctcgcttc atggttacct gatctactac ttcttttgct
    16081 tgcattttca ttccccctac ttttttgcat aaaaaaactc ctgccctaag aggacaggag
    16141 gaatgtttag actgagcgta tactgataca ctgatagcta tactatgtca atgagcaatc
    16201 tacttatggc gcaccatacg tatccttgct cccacccttc ttagcctcac gggactaaac
    16261 ttaaaggaat tctattaagt tttatgcttt cgttgttaat tactataccg ttatctaaat
    16321 taaaatgcaa tgttttttct taatttttct aaagtttttt caaaaacttc tggaagaggt
    16381 gcttcaaaga tcatcttttc gtttgtagtc gggtgcgtaa aacctaacat ttgcgcatgg
    16441 agaaactgac cattgccttt caaagttttc ttcggtccgt atactggatc tccagctaac
    16501 ggataaccga tatacttcat atgcacacgg atctggtgtg ttcttccggt ttctagtttt
    16561 aattcaacca gagtaaatcc ttcgaaacgt tccaatacag taaaatgtgt gacagccgac
    16621 ttcccatctt ctcttatcgc ctgcattttc cggttttcct tcgaacggcc gattggcgca
    16681 ttgatggttc ctttttcgtg aggaatctct ccatggacta aagcaacata tttgcgcaaa
    16741 gaggtcttat cttttaattg ctgagctaat gattcgtgtg cctggtcatt tttggcaacc
    16801 attagcagtc cggaagtatc tttgtcgatt cggtgaacaa tacctggacg aataacgccg
    16861 ttgatcgtag aaagatcctt gatatggtac atcagcgcat tgaccattgt gccatgcgta
    16921 tgacctgctg aaggatgaac gaccattcct tgaggtttgt ttatcaccgc tacatcttca
    16981 tcttcgtaaa cgatcgtcaa cgggatattt tctgggacca catctaatgt ttctggttcg
    17041 gggatcaaga cagtaatctc gtctccttgt tttactttgt aatttgcttt gactggctgt
    17101 ccattgacag aaaccgctcc atttttcagc cacagctgaa tttgcgaacg actgtaatcg
    17161 gtgaataaat tagtcaatac tttatcgatc ctaccagatt catggtgaat cgtcgtttta
    17221 agttctgtca tttttttctt tgatcctttt catctaaaat aatataaatt aacatacaaa
    17281 tcactccaca tacaagtgtc acatctgcta cgttaaaaat cggaaagctc ataaaatctg
    17341 tctggaacat atctactaca tagccaagac gaatacggtc gataaaattg ccaatcgcac
    17401 cagctagaat caaactcaat ccaatcatga accagcgatt acctttttca cgatttttaa
    17461 tcatcaatgt gagaatcaca acgactgcaa tgagtgtcac tatagtaaag aaccacatct
    17521 tcccttctag catactccat gcggctccag tgtttcgaat atgattcagt gacaaaatac
    17581 ctggtataag atttttcgtc tctccaagcg ctagattatc agtgatccac catttgacca
    17641 actgatccac tcctactagc aaagcgctga atatccaata aataattaac aaaaaatcaa
    17701 tccttttcta tttgtttata aatatcacga ggtcgtacga tcccgagcag attaccatcg
    17761 ggattcccat ctttagtgat aagtacggct tccaaagtcc cttgctcacg aaacatcgct
    17821 tcaacctcgt aaatatgtgt tttagctgga acaaaatgat aatttgtgta ctttccgttt
    17881 tggatgatca aatccaacgc tcgtttattt gttaaatcaa ccggaccttt ttggctttct
    17941 tttgctagcc aaaacccgat attacgtaaa gtaatcaatg ctacaaattt tcctttattg
    18001 tataacggaa attgtgaata ccttttttct gctactatct ttaacagttc aagtaacgga
    18061 agatcttgtt caaaacctgt tacacgtttt gcaaatcgag gcagcacggt ttcaggctga
    18121 atcagttctt gttcgatcag ctggattcgc ttgactgtcc aatcatttgg ctctgcaatg
    18181 acaaaatcga ctgcgatccg atcatggacg atcgcattcc ttaactgagc aagctgtaaa
    18241 agatcatctt cgtattttct gatcattaat tgttttcttt gagctaggcg tctgacaagt
    18301 tcggtaaatc ccatatttcg tgcatttccc atctcgtctc tcatccattt ttcgattcga
    18361 ttgaaactga ttaaaaaaag atcagagttt gccataattt tcctccttga tcaaatatgc
    18421 ccggtttttt atatagaaaa agaacgcaat caacacaata actgcaaaaa aactgaaaaa
    18481 taaattttgt aggaaaacgg cccccaaccc agttgctaga aataaaaacg gatagatttg
    18541 aagaatcaag taattcattg tgatcacata agcaggcttt gcttctttca ctgtataaac
    18601 ggggcttttt agccaataaa aggtgacctg catcgtaaag ggcacttcca gatcaagcgt
    18661 tatcttttgt tcatgactga gaacactgcg tttttcattg ttgattctta gctgaatcga
    18721 gctacccata ccgtaaaaac cggtttttct tataaatgtc gttttcatca taccctccta
    18781 ttatgcttta gtatagctca aaatacaata aagaaaaaga atgatcctag tgtaaacaaa
    18841 attaattccc tatcgtctaa aaaaagaagc tgtagtcaaa atacagctcc ttcgatggta
    18901 gattataatc aagcttaaaa caatcccaac acttctccgt catttgtcac gtccatattc
    18961 aatgcagcag gttttttagg caaaccaggc atcgtcataa catctccagt caaggctact
    19021 aaaaatcctg cccctaattt tgggatgatt tcgcggatcg tgatggtgaa atcttccggt
    19081 gcacctagca gtgaaggatc atcagaaaat gaatactgtg tttttgccat acaaatcggc
    19141 agtttgtccc atccattctt cgtaaactct tctatttgtt tttgcgcttt tttgctgaaa
    19201 acaacaccat ttcctccgta aattttcttg acgattgttt ctgtcttttc ttgtatcgtt
    19261 tcttctaggc ggtataatgg cttgtaatta gcttcttttc tatcaatcaa tcgtactaca
    19321 gcttttgcta aatcaacgcc gccttctgct ccatctgccc atacactcgc tctcttggca
    19381 agaatcccct gattttcaca caagtgctcc aacagtgtga gttcattgtc tgtatctgtt
    19441 acgaattcat tgattgcgac gatcacaggt agctgatatt gttccatatt acgtatatgg
    19501 cgctttaaat ttgcaaaacc tactttcaaa gcatcaagat tctcattttt aagttcatct
    19561 tttttcattc cgccatgcat tttcaatgca cggacagtgg cgacaatcac cacagcatcc
    19621 ggcgcttttt tcaagttagg tactttgata tctaaaaatt tctctccgcc aagatctgca
    19681 ccaaatcctg cctctgtgac aacgtaatct gctaatctca atgctgtctt ggtagctaaa
    19741 atactattgc agccatgagc gatattggca aacggtcccc cgtggacaaa agctggtgtt
    19801 ccgtaaattg tttgtacaag attcggcttg attgcatctt tcagcagtaa tgccagagcg
    19861 ccttctgctt tcaagtctcc agcagtcaca ggctgacggt caaatgtata gccgacaacg
    19921 atccttgcaa gacgagcctt taaatcttca aggtctgccg caagacacaa gatagccatg
    19981 atttcgctgg caactgtgat atcaaaccca tcttctcttg gaacaccttg gattggccca
    20041 cccaagccaa caattacttt acgcagttca cgatcattga gatcgactac ccgtttccaa
    20101 atcactcggc gggcatcgat gttcaattca tttccttgat gaatatgatt atctaaaaga
    20161 gcagataatg cattattagc tgttgtgata gcatgcatgt caccagtaaa atgcaagttg
    20221 atatcttcca taggcaatac ctgtgcatat cctccgcctg cagcaccacc tttgattccc
    20281 atcacaggac caagtgaggg ttctcgcaat gcaataacag attttttatt gattttattg
    20341 agcgcgtctc ctaaccctac agtgatcgtt gactttcctt cgccagctgg tgttggattg
    20401 atggaagtaa ctaagatcaa atgcccctca gcgttatcct ttgatcgatt gattccagaa
    20461 aaattgattt tcgccttata tttcccatac agttccaaat cgtcttcctt aagatctaat
    20521 ttactagcca cttcaacaat cggttctagc tctgtttctt gtgaaatttg cagatcattc
    20581 ttcatttgat tacccctttt cacgaacttt attcaacaaa atatcttctt tgttaagata
    20641 tgccaattat accttttttt attcagaaaa aaaacataaa attacaggtt tttaatttat
    20701 ttgacgtact tataaatact ctttataatg aaggctatga tcagacttta gaaaggtcgt
    20761 gagtgctttg accacaggaa ttgtaaaatg gtttgacaac aaaaaaggat acggctttat
    20821 cagttatgat gacacagaag aaatttttgt acattttact gcgattgaag aagagggatt
    20881 caaaactttg gaagaaaatc aagtggtcga atttgagatc atcgaaggga atcgaggaac
    20941 acaagctgcc catgtcaaga aaggcaacgt tcagactacc gatactagta tgcatgaata
    21001 gataaacaaa tagagtgaga cgctaaacgg gatgaaccgt acgtctcact cttttctttt
    21061 cctgtaaaaa ttcgtttttt taggttctga tttttaaaat tagctttttc tttttttcgt
    21121 ataaggataa ggaattgatt ctgatttggg tccgtttttt tcaaaatgat caaaaaggac
    21181 tacttgatct ttttttcgca tcatgaaaac agatggggct ttctcatctt gcaacatcat
    21241 ttgcacccca gtattagttg gcgtcaaaga tcgaatctgt ccgacagata tttctcggtc
    21301 tttccaaaaa gcagcataac gtataatcac agagtttgat tttaaaataa aagaacgccg
    21361 caaacctaga aatagaaaaa caagaaaaat acctaaaaca aaattgcttt tccaataagg
    21421 acctgtgttt tctaaagaaa gaatcagact aaaaaacaga atgatcaagg tcaatgacca
    21481 atagatgatc gtatgtgcca gttcaggctg ccatcgaata ttttttttca ttctctaacc
    21541 tctcaccgat tcagtaatga tataatctta ccataacatt agtttgaaca aaaaggagaa
    21601 tctcttttta tgttaaaagt atacattgat gcctctacaa aaggcaaccc tggtcctagt
    21661 ggaggtggaa tcttgattgt ctatcaaggt aaacaagaac agctatctat cccgctttct
    21721 atagggacaa accatcaagc agagttcgaa gtctttttaa aaactttaga atttctaaag
    21781 aaaaacgact tacagaatga aacgattttc tgtttttcag acagcaaaac actagtttct
    21841 acggtcgaca aaaacgcaac gaagaacgag ctcttccttc cctaccttca aagaatccaa
    21901 gaacttctat ccgaattttc tttattgatc ctgcaatggt tgcccgaaaa caaaaataaa
    21961 ggagcagata atcttgcacg tcaggctctc cataaacaat taaaagaaaa aaagactctt
    22021 taaattaaaa actttaagga gtctttttat agtttctcat ttaatataaa agataattgt
    22081 gatcaaacgt aatttccaat tggtaatctc cgattttttc ttctatttga ctacgtaaga
    22141 ttctttctag ttctgtatca acaaactgga atttctcagg gaccactaca tcaaattgca
    22201 gcgtttttcc ttgatgaatt actctaaaat catgaatatt aagccctgta cctgtttcaa
    22261 gaagaatttg ctttaactgc cgcaagatat tatagtattt ttcgttatca acaggcattg
    22321 gatccaagtg acagacaagt tccacatcca aagacttttt aaagtctttt tctatcagat
    22381 caataatctt atgagccaca ttcaaattca ttgattcatc tacttcgatg tggactgatg
    22441 caaagcgttt attgggtcca tagttatgca ccaataaatc atgatagcca agtatatcat
    22501 cgcaagcatt taaatgctct tccatttctt caatctctgc tggcgttggg cgacttccta
    22561 atagttcgta tacaaaattt cgaagcatcg tcaatccact ataaaggata tataatgcta
    22621 aagcaaaacc tatatatcca tcaatacgcc atccagttac ccattcgatt gctgctgaaa
    22681 gcaatacagc cagtgtagta aagacatcat tataactatc tgttgctgta gctctcaatg
    22741 tttcagaatc aatggattgc gcaataacct gatacatttt gccttgtgca aatttcaaaa
    22801 agatggaaat gattaggaca aaaaagacga tgggtgttaa agagacattt tctggatgga
    22861 tgattttttc agcagaagac tctaaaaatt gaaatcctac ataagtaatg atgatcgaaa
    22921 caaataaccc actgatatat tcgaagcgtt cgtgtccata aggatgttcc tgatctgctg
    22981 gctttgcagc aattttaaat ccgatcaaag tcaatatgga tgaagcagta tctgatagac
    23041 tgttcactgc atcagccata atggagacac ttcctgaaaa aagcccgatc attagcttag
    23101 agacaaacaa gatcagattc gtaaccaatc ctaagatacc cgctagtact cctttttttg
    23161 tccgctgttg cggtatttgt ttcttttttt cttcttgttt cttagccaag ttttttaccc
    23221 cttctagttt gcttgttgct caggtaaaaa gatggagagg acgattgttt tcctctcctc
    23281 tcttcctttt tctatctatc gtgcgtccta ttactattaa aagatggtca ttattctggt
    23341 ttcaacggtg ttgctgcaaa taacgctttt gctagtaatg gtgttatgat tcccgcacct
    23401 attgcttctg gtatcccatt gattgctgca acccctgcta aggttttaaa taaaagagca
    23461 gagtctacac cataggcatc tgccgttgca cctgtataaa ataatcccat gaatcctaac
    23521 actaagactg tattgaccaa tgaacccagt acccctgcaa aggctgagct gatcgttatt
    23581 gatttatttt tttgataaat ccagtggaaa accaagcctg ctactaagcc aacaagtact
    23641 ctgggaacta ccgagataat cggattcgtg aacactaatg tatcaaatgg cgttgttggc
    23701 atggcatagg cacgaacaat tgtagcgatt ccccaaaaca agccaatcac catgccatct
    23761 tttgggccta atactactgc agcaataatt actgtgatat ggataattgt taaactaatg
    23821 aatcctaatg gaataaaccc cagccaagga accatcgctt gtacgatgat gattgctaac
    23881 aagatcgcac gtaagactag tcgaaaggtc ttatttctac tattcatttt ttcacccctt
    23941 tttatttata ctaatcgtaa aaatttctgt cactttcgtc aactaaagac catccgaatc
    24001 cgaccatttg attagatgcg ccatccaatt gaaaaaagta tgagggcaag acttgtttgt
    24061 cttcgccccc ataatcatgt ttcgttcaat gtttgaactt ttgtttttct gtcaaacgta
    24121 aacgccctat tgttgcgcaa cccattcttt cgcagcttta agtgcatctg gaataccagc
    24181 aggatttttc ccgccagctt gtgccatgtc tggacgtcca ccaccgccac cgcctacttt
    24241 cggtgcgatt gctttaatca agtcgccagc ttttagtcca gcttcatttg attctttcgt
    24301 cattgccgct agcagactga cttttccttc ttgttcgttt gctaaaacaa gaatatctga
    24361 aatatttttt tgtttccatt ggtcagctaa ttgacgcagc tgattcatat ctttcacttt
    24421 tacttgtgct gcaatgattg tttttccatt gatcgtttct ggatctttga atacatcacc
    24481 agcttgttga ttcgctaact tgctagctaa ttgttcattt tccttttgta gctctcttac
    24541 ttgctgttgc aattgttccg cttttgaaac aacttctttc aattgaggtg atttaacaat
    24601 tgttgctact tgttttagtt gtttttcttc ttcttcaagt agttcgtacg cttctttact
    24661 tgttacagcc tcgattcgtc gcacgcctgc accaattcct gattcagaaa cgattttgaa
    24721 gattccgatg ttttctgtat ttgctacatg tgtgcctccg cacagttcga ttgaccagcc
    24781 gccaatattt actactcgaa cgtcatgtcc gtatttttca ccaaacaaag ccattgcacc
    24841 catgtttttg gctgtatcga tatctgtttc aattgtttca actgggatag cttcccagat
    24901 tttttcgttg acgattcttt ccatttcagc taattcatct gaagtgattt gaccaaagtg
    24961 ggtaaagtcg aatcgtaaat gtccaggagc gactaaagaa ccagcttgat ttgcatgctc
    25021 gccaagtact tctttcaatg ccttgtgcag tagatgggtt gctgtatggt ttttgatgat
    25081 ccgattgcgc atcgattgat cgatcaatag atgataggtt tgtccttcac tcattggtgc
    25141 ttttacttct acggtgtgca taaattgacc attaggcgct ttttgaacat ctgtaacaac
    25201 tgctacgatt tcgcctactt cattcatgat ccatccttga tccgctactt gcccacccat
    25261 ttctgcatag aaaggtgttt gatcaaagat catttgagct tcaccttctg cgacttcatt
    25321 caaaagagac tcacctttaa cgatgaccaa taattgacta tctgattctt gttctgtgta
    25381 tccaatgaat ttactttcta ctttgatatc tgtcaataaa gcagattgta cccccattga
    25441 tttttcagta ctgcgggcag agcgagcacg ttcgcgttgt gcatccattt ctttttcaaa
    25501 accagcatga tcaactttca gtccttcatc ttctgccacc tcttccgtta attctaccgg
    25561 gaagccatat gtgtcgtata gtttgaagat gtcttttcct gctagagtcg tcccgttttc
    25621 gttttttact tcttggatca cttgatttaa gatttccaaa ccttcattga ttgtttcatt
    25681 gaaacgttct tcttctgtac ggataacttt ttcaataaat tctttttgtt gaagtacttc
    25741 aggataataa cttaccatga tttccccaac aacagggact aaacgatata agaatgcttg
    25801 ttcaatacct aattttttcc catgcatgac agcacgacga agcaaacggc gtaagacata
    25861 ccctctccct tcattcgatg gcaatgcacc gtcgccaata gcaaatgaaa gggcgcgaat
    25921 atgatctgcg attactttgt aagaaatatc tgttactggg ttttcaccat attttacttg
    25981 tttgcttagc ttttctacgg cgtggataat aggcataaac aagtctgtct caaagttcgt
    26041 tgacgcatct tgaacgattg agaccatgcg ttccaatccc atccccgtat caatgttttt
    26101 atgaggaagt ggttcaaatg tgttatcagg cttatggttg aattctgaaa atactaagtt
    26161 ccagatttct aaataacgtt cattttctcc tcctggatag ttttcaggat cgtcttctgc
    26221 taaatcgtta taagcttctc cacggtcata gaaaatttcc gtatccggac cacatgggcc
    26281 tgcaccgata tcccagaagt tgtcttctac atcaataatg tgatctagtg gcaggccaac
    26341 ttcttcatgc cagatgcgtt ttgcttctgt atcttttgga taaactgtta cataaagttt
    26401 ttctggatcg aatgccatcc attttggatc agtcaaaaat tcccatgccc agtggatggc
    26461 ttcatttttg aaatagtcac caatcgaaaa attacccagc atctcaaaca tcgtatggtg
    26521 ccgtgctgtt ttaccgacat tttcgatatc atttgttcga atagattttt gggcatttgt
    26581 gattcttgga ttttctggca caactgaacc atcaaaatat tttttcaatg ttgcaacacc
    26641 agagttgatc cacaataagg ttggatcgtt cacggggatc aaagacgcac taggttcaat
    26701 cgtatgtcct ttagattgga agaaatcaag aaacatttgt cgaacttgtg cactacttaa
    26761 ttgtttcatg tcattacctg ctttctataa attaaataca aaaaaacacc atcacagcca
    26821 aggacgaaaa ctcgcggtac caccttgatt gcaatgatgt gtaatcatta cctcttaaac
    26881 tcgataacgc tgagctgcgt cggtatttct accaaaatag aaaaagggag caatttgatt
    26941 agtgactatt cttttttcag ccaagaaaga attttctgtg agtcttaaaa aacaaatcat
    27001 atccttttcg tacttaatta gtatacgcat tctattgatc actgtcaata tctcaatttt
    27061 tattttcatt tccttttggt catactccac gatttttggt acgataagaa taaaggaatc
    27121 aatacatctc tgctattcat gacaaggagg aatatgatga aaaaaatagt tggagcggat
    27181 gaatggatac gcgcagctag ctgctttttg agatatcaag tttttgtatt agaacaaggg
    27241 attcctgcag aactagaatt cgacggaaaa gatatcccgc aacaaaccta ttatctattt
    27301 cttgatcaaa aaagaccagt agctactttg cgttatgaaa agaaaacacc tacttgcttc
    27361 aagccggaac gattttgcgt agcaaaagaa taccgaggaa aagggttagg cggtcagttg
    27421 cttgaagctg ctgaaaaacg ggcggtttca gaaggttgtc agactagtta tgtagtagct
    27481 gaaatgacgg ctgtagattt ttatgaaaaa caagggtatc atacttgcac agaacctttt
    27541 attgaagatg aagtactttg tatcggaatg aaaaaaagtc tagcttaaaa acaagagatt
    27601 gtgacacgcc ttttgtcaca acctcttgtt ttttatttat gtgaattttt cttattttta
    27661 cgagcagtac ggctttgctg tctgcgttcg attttgcgtt cttttttatt tttttctgca
    27721 attgcccaat cgattttttt cttataacca ggcttgatct ttttcttttt cttcttcaca
    27781 agaccaatca gcgtgggatc taatacatct tttgattttt ctcgtttggc acgtctatta
    27841 cgatcgtatg ttttgacgat ttccccgttt ttgatttctt ttggttcaaa tgagacgccc
    27901 aatttttcta tcgcatcaat ggcttgctca tcatttggcg aatataacgt aatggccgtt
    27961 ccttttaagc cattacgtcc agtacgtccg acacgatgga taaagaagtc tagatcttct
    28021 ggaatttctg cattaataac atgagagaca ccttcgatat cgatccctct agcagctaaa
    28081 tcagtcgcta caacatattg atactccaga ttctgtactt gtcgcatcac tcgttttctc
    28141 tctcttgggg tgatgtctcc atgaatcttt gctactttca agccttggtt tttcaagtaa
    28201 tcggcaattt catccacatg ctgttttgta ttggcaaata cgattgctaa ataaggatga
    28261 ccaattgtca gcagttgata aatcatttga ttctcatctt taccttttgt tgaaatcagc
    28321 caattttcaa tgtcttcaga aataactgct tttggtttga tttcttcaat gattggattt
    28381 tccatgtatt ttcgtaagaa tggacgaagt ttttctggaa tagtggcaga aaaaactaaa
    28441 aactgcagct tttctggtaa tcgacttgca atttggtcta cttcatttaa aaaacccata
    28501 tccaatgtca tatccgcttc atcgacaaca aatgcaaatg cggtgtgaat cttcagcgct
    28561 tgttcattca tcatgtctaa tattctacca ggcgtgccta ctacaacctg tggctgttgg
    28621 tgatgcagac gatttaattg acgctgtttg tctgtaccgc cgacaaaatt cgagacacgg
    28681 atctccggtg tagaaaattt agcgatttgt gtagctgctt catagatctg tgcagctagt
    28741 tccctacttg gagctgtaat aacaacttgt acttcctctt tttctgcatt gattttttca
    28801 aacaaaggca acaaaaacgt atgtgttttt cctgtaccag tttgagattg cccaatgata
    28861 ttttttcctt ttgcaattaa aggaatcaaa cgttcctgga cctctgtggg ctgtttgaag
    28921 ccctttgcgg ttaacgcttc attgataaac ggtttgaagc ggaatatatc aaaattattc
    28981 attcgtgcac ctcttctctt taaattatca cgactttggc attataacac agacaaagcg
    29041 tttttgctca gctaatttcg agaatcatca tcctttgttt ggccaatcgt gctaacagta
    29101 tatgtgtgac tagctttttc ataaaacaga atccgttttt ttctcaaaaa tgatagcaag
    29161 atatttaaaa taaaaatacc ttgtagtaac aagacaccga gagaaatgaa tactgcactc
    29221 atctgcaaca ccgtattcgt tgtcgaattc atgatttgct gaagcaactg ccccaaccag
    29281 cttaaaccat aaaaaagaaa gtacagatac ccgtagcgga tcatcaatgc ttttaaagaa
    29341 attcgttcgc ggtcttcttc caccaaacgg atacgcacaa tttttttgcc aagtgtccat
    29401 ccattggtta taaacggtac aatcataaag tataccccta cttctaataa aagccaccag
    29461 atatgagaag taactgcccc tgaatcgaac gcaattttaa agaaaatcgc cgctaccaaa
    29521 ttaataagag ataaaaatgt ccagtcgatc aaataagcga ccaagcgtcg agtcaatgag
    29581 acagtctttc ctttttcata agaaagttca tccattcgtc ttcttgtagg aagcataaat
    29641 gtaaataacg gcgtaacgac aaaaccaatg attccaccca atgtatttgt cactaaatca
    29701 ttcacatcaa ataagcggta tggtcttggg tagataaaat aaagtccact tagctgcgtc
    29761 aattcaaaaa atagagaaag gcagaaacta gcaatcatcg ttttcataaa agaaagccgg
    29821 aaataatatc ttaaataaat gccaaacggt atgagtaata aaacattaaa agctggttcc
    29881 aaaaatacac tctgcttcat tgccggcagg taggtactag gttcagacaa gaccaatacc
    29941 gtgttgtctc tgaaatgttg ccatgaagca aataaatgca gctccatctt tggccctgtc
    30001 atttgggcaa ccgtctcctt tgccggaagt ggtaagatca ccaaaaaata cgcacacaat
    30061 aaataaaaaa cgaaagaata caaaataact gcccttgtta ctagaaatgt tccatacttt
    30121 cgatattcat aaataaaaaa aacagatgag atcgctaagg ctaaaaatgg aaaaacaatc
    30181 agcgcaaaac gaatcggttc gatataactt gccatatgac tcctccttga ttctttgtat
    30241 ctctcttatc ttagcagtcc tttgctgttt caagcaagta acgaggctat tatttctcat
    30301 ttctttcaaa gtaaagtaag ataaacacaa agggggtgtc gagatgctga atatgtactt
    30361 tgtttttggc gtacctattt ttttactgtt cctttatgct acgatcgctt atgtaagaaa
    30421 aagaactaca attcattatt taggatttat tctcctgatt atttcgggtt tcatgctagt
    30481 cttcaatctt cagacttggc agcaagcact tcttgaaatg gataaaatga ctccacatgc
    30541 tttgtctaaa gtgcttggct accctgtcta tctgatttgg cttcccattt tcatttctgg
    30601 ttgcttggtt ttattaaata tttatcgcgg cgtacgccga atagttcagt tacgcaaatc
    30661 aaagtaaaag acagaaatcg gttgagcccg atttctgtct tttactttgc tatttcatcg
    30721 tagacaaaac gacatttacg tgatcaaaat taacgagtac ttttgacatt tcttccacgt
    30781 actcctcatt taaataaaat attttgtttg gcagagaagt gcagttctaa taaaattcga
    30841 atgttttagc tatctacgtt ttaaatagag ataaatcggg ataccagcaa gtgtcaatac
    30901 tatccccatc gaagctaaaa aggtctgagt gataagcgtg cttgatacga taaaagtccc
    30961 tccaatgatt gctactagtg gaataaacgg atacattgga actttgtatg gtcgaaacaa
    31021 atcaggttct tttttacgaa gaagaatgac accaacaaag accatcgtat aaaaaatcca
    31081 aatgacaaag atcagcatat ccgttagtgt atcaaaacca ccgatcatca tcatgccaat
    31141 agcgatgact agctctaaga tacctgcggc tacaggaact ttagttttat catgaagttt
    31201 agcaaagagc ttgctaaaag gcaggttgtt ttcttttgcc ataacataag ggagacgcat
    31261 tccagtaagg gtatagccat tgatggttcc ataaacagaa atcaagatac caactgtgac
    31321 cagtcttcca ccgaagccgc caaaaatcat ttttgcaacg tcacttgccg cattgctgtt
    31381 tcctgcgact ccgtcgatag atgcggttct taagaacacc gcatttacta ataaataaac
    31441 gatcatgatt ccgatgattc ctaaagaaat tgcttttggc aaatctttcg ccggcttttt
    31501 caattctccc gaaatatttc ctacgtgtat ccaaccgtcg tatgcgaaca tcgttgctag
    31561 caagcccgct cccaaggctg agaaaaatga aagattttct cctgcttgga tcggaaacag
    31621 ttggaagtct actccttctt gtcggaacaa accgaaaatg acgatcacaa acaaaggaat
    31681 aagcttgcag acaagcgtaa tcgactgaaa agcccctcca gctttagaac ctaaaaaatt
    31741 gatcaacagg atcgatacag cagctgtaac agctacggga acaatcattg actgggaaag
    31801 accaaataga ttgacgaact gtgtaccgaa aatgatcgac aaggctgcta catttgctgg
    31861 aaaataaatc acgacttgcg cccagcccaa taaaaaagct gctgtatttc cgtaaatccg
    31921 ttcgatatat ttaatcatcc ctcctgtttc tggaatagca gctgccagtt cagctcctgt
    31981 tagtcctgca cagacagaaa tcataccacc gagaaaccaa gaaaacatat gcaaactggc
    32041 ggatcctgta acttctgcta cgcttgcggc tttaaaaaat acccctgcac cgatcactgt
    32101 gcccataaca gtcgataaag cagtaaaaaa tcccatcgta cgttttaatt cattttctat
    32161 ttttacttct tttactggcg tggcttgata ttcttccatc ccttgtcccc tttcatacca
    32221 tagccaatcc caaaagtata aaaaactttt tggatgtggt tcttgtttta taccgtctct
    32281 accaattttt ctttcagttt ttccaacata tcctttgtca tcacatctaa gtcgtatttc
    32341 ggcgaaaagc cccattcctc ttgcgcacaa gaaacatcta gtgaatttgg ccaagattct
    32401 gctattgact gacgtacagg atccacatca taatccattt caaaatctgg tatgattttt
    32461 tgaatagatg ctttgatctc ttccgggtca aaagacatcg ccgatatatt gaaggcattt
    32521 cgatgaacca atcgatcagg atctgcattc atgagtttta taatggcatc gatcgcatct
    32581 ggcatataca tcatatccat tgatgtacct tgatcaatga aactagtgta ctttccttct
    32641 ttgattgctg aataataaat atcgactgcg tagtctgtcg taccgcctcc tggcaaggtt
    32701 gcataagaaa tcaatccagg gaaacggaca ccacgagtat ctacgccata tttcacataa
    32761 taataatcac atagtagttc tccagctacc ttcgttaccc catacatggt tgtaggacgc
    32821 tgaagagtat cttgtggggt atgatctttt ggagtatttg gaccaaacgc gccgattgaa
    32881 cttggcgtaa aaaatttcag ctggaattct ctagcgactt ccaatgcatt gaccagccca
    32941 gtcacgttca aattccaggc taattgtggt tttgcttctg caacagctga caaaagagca
    33001 gccaaatgaa tcaatgtgtc cacttgatat tgttctgcta tgctgcgcat tttttcgtaa
    33061 tccattacat ctaggatctc aaagatatcg tttttctcaa tgacttcagg catgcgtata
    33121 tctgtcgcaa tgacattttc actgcctagt tcttgacgta gccgtgtgat caactctgaa
    33181 ccaatttgtc ctaaacatcc tgtcaccaat acttttttca tgatgatcct ccctgatctt
    33241 ttttactact atcttcagat gattaacaat atatgcgtga acatgttctc taattttaaa
    33301 tagacgaaaa aactaaattt agttaaataa tttccatttc ttttcctatt ttttgataaa
    33361 ctgctactgc ttcatcaagc atttccctcg tatgttccgc agtcggcata tttctgatcc
    33421 tgcctgtccc aagaggcaca gttggataaa cgattggttt agcataaatc ccatgttcga
    33481 tcagcttctt agagaaagtc tgagtcactt tttcgtctcc caaaatgact ggagtaatag
    33541 gtgtttcaga cataccgatg ttatagccta cttttttcaa ttcttcttta aaataattag
    33601 cattttccca aactttttcg acaagttccg gatgttcttg catcaaagta atcgaagcca
    33661 atgcagctgc agctgcacct ggagttagcg aagtagaaaa taggaatggc cgacttctag
    33721 ctttcaacca gtcgattagt gttttcgatc cagctacata acccccaaca acacctatag
    33781 ctttcgataa cgtgcccatt tgcatatcga ttttgtcgct taatccaaaa tgcttgacgg
    33841 ttcctgcacc ttttccagtt acgcctgagc cgtgcgcatc atcgacgtag gtgatcagtc
    33901 catatttttc aacaatcgga ataatttccg gcaatcgtgc aatgtctcca tccatggaga
    33961 aaacaccatc tgtgatatac atgatttttt tatatttctt actttctatc gcttcctttg
    34021 cttttttctc aaggtctttc atatcttgat gtttaattcg gatgattttt gctccggata
    34081 agcggcaacc gtcaataata gatgcatggt ttaattcatc cgataagata gcatcttctt
    34141 ttgtcattac tgcagagata gcgcccatat tgcagttgaa tccagattga aaggcgattg
    34201 ctgcttctgt ccctttgaat tctgcgattt tttcttctaa ttgctgatgg attttcagcg
    34261 aaccattgat cgttcggact gctcctgctc ctacaccata agtttcggtt gcttcaatac
    34321 atgctttttt caattcttcg cgattggcaa atccaagata attgttggat gctagattga
    34381 tcatcttttt tccgtctacg atgatacaag caccattttc actttctagt atgtcgatcg
    34441 tattgtataa ccccttttct ttcagttgat ccaattcttt ctctaaatac attgttagtt
    34501 ctttggaaga cattgtctcc acctccatat tcatctgtct tgcagaacat accaaacata
    34561 tatcgtgtca ttcatctaca aagcaagtat gctatatttt tgataacgct tacactgatt
    34621 atgagaatta tttaaccaca ttttttattt acagtatctt tttactttca aatgacttat
    34681 atagtatgaa caattacctt ttagataatg atctatttta ctctacctgg gcagataaat
    34741 acaacacaac cattgataga agccctttcg ttaaaatcaa ttgtattctg aatatttaat
    34801 ttatttattg catagaccaa taaaaataca taaaatttcc atcttcgttt atcagcaatt
    34861 tttaatttta ctctctgaat atttcttaaa agttttactt gttgaattcg aaaaaaggac
    34921 tgtgacaaaa gtcttgtcac agtcctattc ttccgaat
//
LOCUS       DAIGSZ010000025        34899 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.025, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000025 DAIGSZ010000000
VERSION     DAIGSZ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34899
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.025"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(56..1285)
                     /gene="rpsA"
                     /locus_tag="NOB31_001282"
     CDS             complement(56..1285)
                     /gene="rpsA"
                     /locus_tag="NOB31_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HCI0973500.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(1420..2100)
                     /locus_tag="NOB31_001283"
     CDS             complement(1420..2100)
                     /locus_tag="NOB31_001283"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HCI0973501.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(2149..2784)
                     /locus_tag="NOB31_001284"
     CDS             complement(2149..2784)
                     /locus_tag="NOB31_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0973502.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(2850..4253)
                     /locus_tag="NOB31_001285"
     CDS             complement(2850..4253)
                     /locus_tag="NOB31_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HCI0973503.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(4240..5271)
                     /locus_tag="NOB31_001286"
     CDS             complement(4240..5271)
                     /locus_tag="NOB31_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973504.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            5302..5523
                     /locus_tag="NOB31_001287"
     CDS             5302..5523
                     /locus_tag="NOB31_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HCI0973505.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(5688..6425)
                     /locus_tag="NOB31_001288"
     CDS             complement(5688..6425)
                     /locus_tag="NOB31_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HCI0973506.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(6578..7918)
                     /locus_tag="NOB31_001289"
     CDS             complement(6578..7918)
                     /locus_tag="NOB31_001289"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HCI0973507.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(8155..9678)
                     /locus_tag="NOB31_001290"
     CDS             complement(8155..9678)
                     /locus_tag="NOB31_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HCI0973508.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(10056..10667)
                     /locus_tag="NOB31_001291"
     CDS             complement(10056..10667)
                     /locus_tag="NOB31_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0973509.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(10790..10915)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(10997..11713)
                     /locus_tag="NOB31_001292"
     CDS             complement(10997..11713)
                     /locus_tag="NOB31_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCI0973510.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(11719..12288)
                     /gene="scpB"
                     /locus_tag="NOB31_001293"
     CDS             complement(11719..12288)
                     /gene="scpB"
                     /locus_tag="NOB31_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HCI0973511.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(12272..13069)
                     /locus_tag="NOB31_001294"
     CDS             complement(12272..13069)
                     /locus_tag="NOB31_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HCI0973512.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(13039..13410)
                     /locus_tag="NOB31_001295"
     CDS             complement(13039..13410)
                     /locus_tag="NOB31_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCI0973513.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(13429..14316)
                     /gene="xerD"
                     /locus_tag="NOB31_001296"
     CDS             complement(13429..14316)
                     /gene="xerD"
                     /locus_tag="NOB31_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HCI0973514.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(14412..14885)
                     /locus_tag="NOB31_001297"
     CDS             complement(14412..14885)
                     /locus_tag="NOB31_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI0973515.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(14990..15853)
                     /locus_tag="NOB31_001298"
     CDS             complement(14990..15853)
                     /locus_tag="NOB31_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCI0973516.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(16049..18148)
                     /locus_tag="NOB31_001299"
     CDS             complement(16049..18148)
                     /locus_tag="NOB31_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCI0973517.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(18368..19477)
                     /gene="rpoD"
                     /locus_tag="NOB31_001300"
     CDS             complement(18368..19477)
                     /gene="rpoD"
                     /locus_tag="NOB31_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HCI0973518.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(19501..21342)
                     /locus_tag="NOB31_001301"
     CDS             complement(19501..21342)
                     /locus_tag="NOB31_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HCI0973519.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(21524..23839)
                     /locus_tag="NOB31_001302"
     CDS             complement(21524..23839)
                     /locus_tag="NOB31_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI0973520.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(24024..24884)
                     /locus_tag="NOB31_001303"
     CDS             complement(24024..24884)
                     /locus_tag="NOB31_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HCI0973521.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(24943..25464)
                     /locus_tag="NOB31_001304"
     CDS             complement(24943..25464)
                     /locus_tag="NOB31_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HCI0973522.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            25742..26503
                     /locus_tag="NOB31_001305"
     CDS             25742..26503
                     /locus_tag="NOB31_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0973523.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            26529..29120
                     /gene="mprF"
                     /locus_tag="NOB31_001306"
     CDS             26529..29120
                     /gene="mprF"
                     /locus_tag="NOB31_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCI0973524.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(29308..30495)
                     /gene="tuf"
                     /locus_tag="NOB31_001307"
     CDS             complement(29308..30495)
                     /gene="tuf"
                     /locus_tag="NOB31_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCI0973525.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            30863..31219
                     /locus_tag="NOB31_001308"
     CDS             30863..31219
                     /locus_tag="NOB31_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI0973526.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(31460..32464)
                     /locus_tag="NOB31_001309"
     CDS             complement(31460..32464)
                     /locus_tag="NOB31_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HCI0973527.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            32630..33481
                     /locus_tag="NOB31_001310"
     CDS             32630..33481
                     /locus_tag="NOB31_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI0973528.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            33498..33743
                     /locus_tag="NOB31_001311"
     CDS             33498..33743
                     /locus_tag="NOB31_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973529.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            33930..34634
                     /locus_tag="NOB31_001312"
     CDS             33930..34634
                     /locus_tag="NOB31_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973530.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         9844 a         7317 c         6027 g        11711 t
ORIGIN      
        1 agaaaaactg agacaaaagc agctgctttc atctcagtca cagatacaaa atcaattatt
       61 tttcagaatc atcggttgct ttttcttcta cttcttcttt caacgcatca cctaaaatgt
      121 ctcccatagt aaatccagta ttttcttctg gtaattcata agactcaaca ttttttggtt
      181 cttcttctga agctggtttt tcttctaaag ctttgatact caatgcaata cgatgttctt
      241 ctggatggat ctctaatact ttcactttca cttcgtcacc ttcatgaagc acttcatgtg
      301 gtgtcgcaat atgtttatgt gaaatttgag agatatggac tagcccttct actccaggga
      361 acacttcaac aaaggcaccg aagcttgtca aacgtttaac tgttccgtct aatactgtgc
      421 caactggagc ttttgtatcg atttctgacc aaggtccagg ctgtgtgtct ttgattgaca
      481 aggaaacacg ttcttgttca ggattgatag acaacacttt gacatttaca tcatcattga
      541 cagccaatac atcacttggt tttgctacat gactatgtga aatctctgag acatggacta
      601 gaccgtcaat tccgcctagg tcgacaaatg cgccaaaatc agtaagacgt gcaacacgtc
      661 cactgagaac atctccctca tggatagttg aaagaatttc ttttttcttt tcttctcttt
      721 cgttttccac taccgcttta tgcgataaga tcaaacgatt ttctgatggt tcgatttcga
      781 tgattttaaa gctcaatgtt ttgcctttat agtctgaaaa gtctgcaaca aaatgatctt
      841 ccaccattga tgcagggaca aaaccacgta caccgacgtc aacgactaaa ccgcctttga
      901 caacatttgt aacaggtgct tcgatgacct tgccctcttg gaaatctctt tcgatatctt
      961 cccaaacttt tttagcatct aaacggcgtt ttgaaagtag atagctgccg ttttctttat
     1021 ctttgccgat cgtactgata acgactaaat ctaatacatc accgactttt actacttcgc
     1081 tgatatcttc taccggcaaa gttgataatt cttttgccgg aacgactcct tcaactccag
     1141 ccccttcgat tccgacaatc acttgtttgt cttcaatgac taaaacttcg cccttaacaa
     1201 catcgccaac ttttacttct tgtacgcttt tcattgcgtc ttccattgac tggttgttct
     1261 cttgattttg atcaaattct gtcataacac ttgtcctcct aaccaacatt ctgccgtaag
     1321 tacggtactg tttttagttt aattgattat tcaaaaaaaa taaagcgatt tcgttcgttt
     1381 tccttgaaaa aacaattgtt tttcattttt tttcttaatt taaaaaagaa gataaccttt
     1441 tttcaaaaca acagctttta ttgctgcaac gacttctgga atcgatttgc cagtcgtatc
     1501 gatacgaaca gcatcctctg cttgcttcag cggagagacg tcccttgttg aatcataatg
     1561 gtctctttcc tgtatctctt tcgtcagtgt ttcaagatca gtcggaattc ctttttcttg
     1621 gttctctttg aaacgtcttt ctgcacgctc acttacgctt gctactaaaa agattttcac
     1681 ttctgcattc ggtaatacag ctgtcccgat gtctcttccg tccatgacaa cgccaccgcg
     1741 ttcccctatt tttcgttgga cagcaactaa ttcttctctg acttttccat gtgcagagac
     1801 ttcagaaaca gcttttgtga catctggttg acggatttct aaagtcacat cttttgatgc
     1861 tatgaataca tgctgtccat cttcttgttg cgaaaaagag ataggatact ttttgatcag
     1921 cgaaactagc ccttcttcat ctgaaaaaga tacattgttc gtaatagcta aataagttac
     1981 tgcgcgatac atggcaccgg tatctgtata aatataattc aattcttttg ctaatatctt
     2041 ggcaacggta cttttcccag atgaagcagg cccgtcgatt gcaatactga tttgtgtcat
     2101 gatataactc ctttttctca gaaaaaaagc cgcaaagcgc ggctattatt atttaattct
     2161 taattcttga ccagggtaaa gcataaagtt gtttggatct aagccattca attcaaacaa
     2221 ttgatcagtg gtgatccctg cacgctcagc cacttgtttt ggaccttcgc ctgcttgaac
     2281 agtcgttgtt gaaccggctg cagctgatga agaaggtgtt gtttctgctg cattgctgct
     2341 tgaatcccct gcttgataag ttgcctcact tgaggaagtc ggtgttgtct ctgctgcaat
     2401 actgctttct gacgttacac ctgtatcttg agacacagta gattcttccg cgattgtact
     2461 agattctact gttgaagtct cagttgactc ctcttttgtt gtacttgtag aactttctac
     2521 tactgatgtc gaagtttcag aagaagttgc tgctgttgca ttgttgcttg atccatttct
     2581 gatccagaaa taagcacctg ctggaatagc gatacataag accagtaaaa tcaaaaatag
     2641 cgaaagaaat aatgtatttc ctttcttttg ttgtctctga gaacttcttg atgaaacttc
     2701 atcatctgta tcgtagattg gttgttccca tggttcttgt gtttcgttat tttctgtaga
     2761 ttgatgtcta tcttttctgc tcactgtttt acctcctaaa ctctatcgtg tgtattatac
     2821 cataggaaaa agtgtcttgt cctaaaaaat caatgttcca tgtttttttt aaataaattt
     2881 agtaaaatcg ttccccaatg aagttgttca gtcttagaaa aaagcttcct ctttggcaga
     2941 agttctgctt ttgctccatc aatatcacaa caattctgcg gcttttcgga gagtttttcg
     3001 ccaaaataag ctaagatgaa ttttctgcgg cagttttctt cattaatata gcgaagcatc
     3061 tgctgcaggc ggaattcttt ttctttttcc tgacgtttga gccgttccac ccaattttct
     3121 ggtttttcag actgctggat cagctccatc catttttttt gcagctcatc aaagggagct
     3181 tgctctgtgg catattccaa ataaagctca aaactttgtc gctgttctct agaaagttga
     3241 ttaaagaaat aatggatacg ttcatcccca ctttgataaa aaagaattgc tgcactttct
     3301 tcctgatctc tgcctgctcg accgatttct tgtacatagt tttctagact gtctggcaaa
     3361 tcataatgga ccacataacg gatatcagat ttatcgatcc ccataccaaa tgcattcgta
     3421 gcaatgagaa actgcagctg attttttaca aactgctgtt gaagttgtct tctttgagct
     3481 gcatcaagac caccgtgata gtatccaact gtaaaacgtt ccctgaataa atgatacaat
     3541 cgttcgactt ctttttttgt tgcacaataa atgattgccg ctccttgtgc tctttccatg
     3601 aagtgttcaa gttcttgttc tttttgctgc gttttccgaa caaaaagcga gatattttgc
     3661 cgattgactg attgtctgat ctcttttggt ggtcgatcaa atagtacatg acgtatatct
     3721 cttgctacta aatctgttgc tgtcgccgtt agtgccagtg tgaccgggtt tcctaaaagc
     3781 tttcggattt ttcctaactg ttgatattct ggacggaaat caactcccca ttgagacacg
     3841 caatgagcct catctactac atataacgca atattttgtt ttttcagatg ctctaaaaga
     3901 gaaggattag tcaacatttc gggactcaaa aacaaaaatt tatattgcga tagatgacgg
     3961 aggacgtatc ttctttcaga ttgcgaaagt aaactattga aagcagctac tcgtttctcc
     4021 cctcgttttt gtaattgcgt cacttgatct tccattagag aaagcagcgg tgacacgatg
     4081 atgaccagac cttccattaa ataccccgtc aattgatagc aaaggctttt tcccgttcct
     4141 gtaggcaaaa tagcgagagt atcttctcca tcaagcaacg cctgaataat ttcttcttgg
     4201 ccgggacgaa atgaatcaaa tccaaaatat ttttttaatt catttattaa cattctgtat
     4261 cgcttccttt ctcaatagat agatttgata caaacgaaat tctccataat ctaattgtcc
     4321 atctacattc cattcgctaa agcgccactc tcgcacggaa tccttatttg gttccaaacg
     4381 ttcgattgtt tctgcagaga gaatccactc gtatggaaaa tcatcaaaaa acaaggccca
     4441 ctcaataaga tgatctgtta ctgttcctct ttttaaatga cggattgcca tgatctggtc
     4501 aattgtctga ccattcataa acatctgctt ggtgatcatc atgctttgat tgaaattttg
     4561 ctgtaataat gaatcgatca aagcgtgcca aagcgaatct ggccgttttt cgatttgtgc
     4621 taacaaaagg tggatacatc tgctttgttg cagataaacc gctgactcat cattgttttt
     4681 tgccagctga taaggaagca gccctgttcg ctcatttcca gataattggt tagctaaaaa
     4741 atctgctgct tcttctggta tctccgaaaa cagctgcacc aaactctcat acgcagtatc
     4801 aatcaaaatt tcacgtggca attggctttc actaagccat ttttttagtt ggaaagtata
     4861 aaaaggactt gtctctgctg gaagatagtc ttgaataccc gttgccagat tagaaattac
     4921 ttgaacagca aatttaatga gccgccaact agtttcccct gttctgccat agcggtcaaa
     4981 acgcaaacca gtatgttcta tttgatgttc ggacaacata tcagcccctg caggcgttag
     5041 ctttgcttca ttttcattta tttcgatcca accttgctgc gcaatttttt gcaaaatttg
     5101 ataaaactta tcctgcttca attctggaaa actgttatgg ataaacaaaa gttcgtgggt
     5161 aaatccataa ataagtactg aagtcgttcg ttttcccaca aggagttggt aaagagaact
     5221 aatccgcagc ttgtgtcctg atgaaaatag cgataaaata aaaacaatca tattattctc
     5281 cttaagttag gatggttaga aatgtcacta ctatgtaaac ttgtacctga acgctgtatt
     5341 gcatgcggtc tttgtcaaat cgaagcgcca gatattttcg attatgatga agaaggaatc
     5401 gttttatttg cccaagaacc agaggctcat caacagttcg tgatgccgga agaagaaaca
     5461 tatgtaaaaa aagcgtatca aaaatgtcca gttcgagcga ttttattaga aaataaaata
     5521 taaatataaa cgaaacttta aaaacgtaca ctaagttctc taaacttgaa aataagccgg
     5581 gatctgtttc tcttgttccg tgaaatcccg acttattttg aaagattcat ttgctatcta
     5641 tagttaattg actagttttt tcacggaccc tataggaccc atttatatta tttcaacttt
     5701 ttcagccagt tttccaatgt attgacgatc acagtttgct ggtctgcgtt agaaatttct
     5761 gcctctccat ctcctttttg ctcaccatag ctgccaaaac ctccatgatt tccgccattg
     5821 attgatacat actctgttct ttccggtaaa tactgcttag cttcttgata agcttcctga
     5881 ttcaatactt tatcttttgt cgccgtgatc gataaaacag gaacagctga ttctgtcaat
     5941 gttccttttt tgtcgggata acttgccatg aagaataccc cttttaaatg tttgtctgaa
     6001 tgattcttat tgacataacg acttgccatt acgccaccta atgaatggcc accgatcaca
     6061 taatcggaat ttggaaaatc ttctttgacc ttatccgctt tgtttccgcc catcactgct
     6121 agatcaagtg gcattttgac aatagcgact gaaaagccgt tttttgctaa atcttgcgcc
     6181 caaatactat aactttctgg ctctacgaga gcaccaggat aaaaaataag taatggagac
     6241 tttccatgat tctttttctc tccttcaaaa aataagtaat cttctttgtt ttttccttct
     6301 tttaccaaca cttgcgcttc tgacgatggt tcgtacgtat tttgctgtat atagtaataa
     6361 ccggctccac cgagtaatcc taaaatgatg actaagccaa ttagtattcg tctaaatatt
     6421 ttcactttct cccacctttt ctatctgagt gacccctttt tcttaatcaa gtatgattat
     6481 accttaaaaa aataagagag aaatgcaaac tttccagcat caaataaaaa aagacggaat
     6541 atccatttga atatccgccc tttttgtatg tttattttta tttagcacat aaacgataca
     6601 cagcttctgc ataaatttcc attgctttat acatactact taattcccat cgttcattcg
     6661 cctggtgcat aaagtcagga gtatcaggga acatcgcacc gaatgccaca cactggttca
     6721 tcgtacgagc aaaagtagcg ccgcctgata caaacggttc agtcatgtct ccagtaatat
     6781 cgcgatatgt ccccaataga tttttcacta actcactgtc tagtggcacg tataatgaat
     6841 caaggaagtc aaattcttca taagtcaacc catatttttc tgctgtttta gttaatttag
     6901 ctactaaatc atctttcttg aatgtaacag ggattctcat atctacaccg atttttgttt
     6961 gttctggtgt gatttccaaa cttgcaaagt tcatcgttag ctcgccggat tgttcatctt
     7021 ctgttttgcc cacgacagct tcaccagttg cattttcttg aactaatttt cctaagaaat
     7081 tgattgggcc aaaatcaaat acttctgaaa gagcaattgc cagacgagaa atagcattca
     7141 ctccttgtgc tgcatctttc gcgtggatac ttttaccaag aacgacgatg ccttcacctt
     7201 gttcttcgaa atcgaattcg tgttttttca atgcttcttt tacttcagaa agcttttctc
     7261 cagagtaagg agctgcatca ggaacaacat tcaacgctcc tccagctttt acagaaaact
     7321 cgttcgttcc tggtcctgtc aagtaagctt gcaataagcc tttttctgca taaattaaag
     7381 gaaattcagc atctggcgca aatccttgcg taattccttc ttctttttcg ttatattttt
     7441 ctaaacaacg ccataaattt tcttcatctg taccaaagat aaaacgaata cgtgtcttga
     7501 attccacgcc agcatcaatc aaagctttga cggcatacat tgccgcaata gaaggacctt
     7561 tgtcatcttg ggatccgcga ccaactaacc agccgtcttt tatagttgga tcgaatggtt
     7621 ttgtttccca attattttcg tcccctgctg gaacaacgtc catatgacac aagataccga
     7681 ataattcatc tccagagcca atctctgaat aaccgtaata gccttctgga tctttaaatg
     7741 ttctaaatcc tagcttttca ctgatttcca atactttatc caaagcttca atcacttttt
     7801 taccgaaggg atgtccttgt cctgaatctg cttcatctag tacggaagga attcggatca
     7861 attcgctcaa tgattctaat gcttgttcat gatgttgttc tgtcacaaat tttttcatga
     7921 tattatcctc ctaatatgtt aaaaagggtc atgtcaaatt cctccgacac aacctcttct
     7981 tctcaaataa tgacgtttta agcctgctcc atcagcaagc agaatgttct taacaaatga
     8041 tgaaagaaaa aacactcact gaatggagct attgacttat ccacgtgctt atcgatagcc
     8101 gtttatcggt ttcttcattc ttatgataga ccttgtacct gtatttgtct aggtttagaa
     8161 cattgctgct acacctagga tcacacagat ggctacaaat aatatcgcaa ttaatttacc
     8221 ggtaaatttc caccacactg aaacatcgaa acgagcaatt gctacagcac ccattacgat
     8281 agcagatgtt ggtgtaatta agtttactaa accagatgca gattgataag cagtgattac
     8341 taaatcctta ccgacgccgg caaattcacc cataggtccc atgattccca ttgttgcagc
     8401 agctaagccg gaagttgaag gaatcaagaa tgacataggg atatagaaaa taaatgtaat
     8461 aatgatgaat acacttgaag ataatgaact taatccttgt tcgccccaat gtaagatggt
     8521 gtctgtgatt aatccattgt tcataaccac ttggatacca cgagcaacag ctactacgat
     8581 tgctacaccg atcaaatcag aagcaccagc taaaaattca gagacaaatt cagactcttt
     8641 catgccataa gtgattgcta ctacgatgga cattactaag aataacatag taatttctgg
     8701 gaagtaccag tcacctaatg gaagcatgct tttacctaga accgtaccta gtaccggaag
     8761 gtttgttaac cagtttgtca atgattcaaa aatcgtgaaa ttcgcattca aggttgtcca
     8821 aggaatcaaa ctgatgatca tgataccaaa agtaataaag aacaatacat taacatgttt
     8881 ttgttttttc gtgattactt cttgacgacc gattgcttca atatcgaaat gcttcatatc
     8941 ttctttacgt tggttgtata ctaatgattt tgttggatct ttttcgatct ttgatgcata
     9001 acgatacaca tatacaatag aaatagctaa caaaataacg aacatcaaga atcgaagacc
     9061 aataccttca cccatcgaaa tcccaacagc ttgtgaagct acgcctgttg caaaaggatt
     9121 taccgttgaa gctagacagc ctacttgaga ccctactaat acgattgcta cagctactac
     9181 tgtatcaaag cctacagcca tcatgactgg gatcagtaaa gcatagaatg gaatcgtttc
     9241 ttctgccatt ccgtaagtag agccgcctaa tgcaaataac agcatcaata ctggaataag
     9301 cattttttct tttcctttga atttcttcac aactgaagca atcccggcat ctagtgcccc
     9361 tgttttgttg ataataccta aaaatccacc aacaaccaaa atgaagaaag agattgggat
     9421 tgcagcaggt gtttctttag ttagctcccc cgctggtaca cctagcatcc cattgattgg
     9481 cgccatgaaa atatcccaca gcccttgagg attttgttgt actcgttcat atgatccagc
     9541 gacgatgttg cctgcatcgt ctacactata gtgcccagct ggtataaacc aagtaagtac
     9601 agcgattact gcaataataa taaataagac cgtatacgct gaaggcattt gaaatttttt
     9661 cttttttgtt tgttccatct tcttcttcct ttcttttccg ttagagacaa caattttggc
     9721 tctaatgtta ttttatcaaa aagagtatca gaacaaaaat aataacacgc attttgtaaa
     9781 acttttgttc aaaaagttcg tttttcccta ttccctcctc ttttttcagg tttttaaagc
     9841 tttcttcttt ttcattgtag cgtttccttt tttttataaa caaacatttt cgtcttttaa
     9901 aaggagaaga atttcacatt tgcaaagaat tgattgattt ttatgcataa atcaaaaaaa
     9961 tactcaaaac aaacaaataa aacgtttaca ttattgcatg tcttgtattt ttttccaaaa
    10021 aaaaagacca agaaatttct tgatcttttt gatatttatt tgactgctgt atgacgttgt
    10081 tcgaactgat gttgttttcg acttaaccat ggaagaagtt gcgcatgcag cactaaaaag
    10141 acagcactca cgatgaatcc tttgatcaag ttgaaaggaa cgatcccaat cagtacatag
    10201 tttgctaaag acatgcccag catctgtgtt gcgttcagcc ctaaaaacat taagtaaaga
    10261 ggcgtaataa cgaaataatt tgcgatactc ataaaaatag ttagagcgat ggttcctgta
    10321 atgacaccta aaaatttgtt tcttccttta tgctgtttct ttacactaaa gaaataataa
    10381 atcgggaatg taaagatcgt tgttgataag aaactagcag tgtctcctac caaattatcc
    10441 ggagaaaaac ctgtagtcag cagatgtaat actgaacgca agaacgctgt tgcaactccg
    10501 gccgctggac cgaataagaa catgctgatc aataccgaga tatcactaaa atcgatcttc
    10561 aaaaaactaa aagccggcat gatcggaaaa gcaaaatact gtaaaactaa tgcgatcgca
    10621 gcaaacatcg ctactgcaac cattttctgt acacgggtgt tcttcatttg aaatcctcct
    10681 gttaggactc ctcttcagcg aactttttga cgtttctctc caaatgaaaa aactctattt
    10741 tccagggaaa atagagttag agttatttga tcaagcgtcg tcaaataagc tctatcttct
    10801 ttatccagac tatactgtcg gtatcggaat ttcaccgatt cagctatttt tttgcaaaat
    10861 aggtcgtgga ctataaccac cggtcgggaa tttcaccctg cccctgaaga cgaaccttat
    10921 ataatttttg tttacatatt cattatacat atctattcaa aaaacgcaac atctaacact
    10981 tataaaaagt aagtgttcat tttgagtggt tcagcaaact gctgacttct tttttgttca
    11041 gttcacggta atccccagga cgtaggcctt gtaaagtcag atctccgtat ttttcacgtt
    11101 ttagtttttg cacaggaaga ccaactgctt gaagcatatt tttcacttga tgattacgtc
    11161 cttcgtggat cgtcaattcc acgatactgt ggtttgtctt aggatccact gataaaattt
    11221 ggaatttagc tggagatgtt tttcgtcctt cgatctttat tccttttgtc aaaggtgcaa
    11281 gcatcgattt tgtagcgatc ccttttacct ttgcaacgta aactttatcc acttcatgtt
    11341 ttggatgtgt caggcgctga gcaaaatctc catcatttgt cagtagcaag atccccgaag
    11401 tatcgtaatc cagtcgacct acaggataga tacgttcttt taccatcggc aaaagatccg
    11461 taacaacttt tcttcctttg tcatctgcaa cagcagaaat aactccttta ggtttgtaca
    11521 ataaatagta accgtattct tcttgataaa ttgggacttc atccacttcc acagtgtcat
    11581 gtttcccaac ttttatccct aattccctta caacttgtcc gtttactttt acacgtcctg
    11641 caaggatgaa ttcttctgct tttcgacgag aagtgatgcc agcgtgggca attactttct
    11701 gcaatctctc cattacaatt attctccttt attcattcca tcaaagaata gatctggtga
    11761 cacgtcttct tcaagtgaaa tttccatttc ttgtgtatca ggcagttctt ctaatgattt
    11821 caaaccaaaa taatctaaga agtagccagt tgttccatat aatatcggcc gacctggtcc
    11881 ttctactcta cctttttctt caatcagttt atgggcagct agacgctgta ccgctcctga
    11941 aacctgaact cctcgaatct gctcgatttc agctcttgtg attggctgtt tataagcgat
    12001 gattgctaag gtttcgacgg cggcttgaga taatgtgttt gatgtccctt gcgcatatcg
    12061 cttaagtaag ggagccagct cttttttagt cgttaataca taatggcttt ccgtttcaaa
    12121 aatatgcaaa gctgagtgcg agttttgagt gtaagattct tttaattctt tcactaaact
    12181 tgtgacttct gcttcgctga gatttaacag tccgcttaat tcttcattac tgatcccttc
    12241 ctcgccaaca ataaaaagaa gggcttcaag ttcacttaat ttcgtcatgt tcggtatctc
    12301 ctactgctgg ataaagcata attgattcat agttttcttt ttgttgcgca atgatctgcc
    12361 cttttttcat caattctagc aaagccataa aagtagtgac aacttcactt ttagaaggtg
    12421 actcaaaaaa agaatcgaaa gtacagccat gcgcatttct ttttatacgc tcttcgataa
    12481 ataccattcg ttcttcgatc gttgtgtcat cgggcgtgat cgttttttcc actttttgag
    12541 aaaatttctt acgttctaag attttctgca tggcacggat caaatcgatt tttttgactt
    12601 gtcctcgctt caacggcttt tcagcatccg ctaacccatc gatgttcata ggttcttttg
    12661 tgtaataaag acttcgttcc tctgcttttt ctgtcagtct ttcagctgca tatttatatt
    12721 tacggtattc taaaagctga gtgaccaatt cttctcgagg atcttcttcc cataattctt
    12781 catcgtctgt gacgaattct tggacaggaa gcaatgtctt gcttttgatt gccatcaatg
    12841 tagcagccat cactaagtat tctcctgcaa cagctagctc gagtgttttc attgtatgga
    12901 tataattcat atattgctcc gtgatcgtag cgatcggtat atcatatata tcgatttcca
    12961 tttgctgaat cagatgaagc agcagatcga gaggaccctc gaatacatct aatttaatat
    13021 tgatctccgt caactcattc actctttctt ctttttcttt gctagccatt ttccaatgta
    13081 aggctctgtg atttcagttg cacggatgga gacatccggg tacttttcct gtaattcatc
    13141 taacatttga aagcccatat tctcaccgcg ataagacgga ttcaaagaaa tgtcatggat
    13201 gatcagctga tcgttcgttg cccagtaaat accaataatc ccttgaatgt tggttgaacc
    13261 ttctggcgta aagaaaaaaa gttcataatc gtcttcagat tcgtacgtat caatctcctt
    13321 caacaaagaa gttttacctg tcagtttctt atggaaactc aatagtccca tagcaatttt
    13381 acggttttct ttccggtaat gtgttaacat cttctcacct tcctatgact aagcccttgg
    13441 aaaatgctgc ttataaacat ccgtcattct tttcttcgtg atatgtgtat aaatctgagt
    13501 cgtagagata tccgcgtgac ctaacaattc ctgtactgtc cgcaaatcag ctccattttc
    13561 tagcagatgt gtggcaaagc tatgccgcag cgtatgtggt gttacttctt tgtaaatccc
    13621 agcctctcgt actaactgct tcagattttt ccagattcct tgccgagaaa gacctttccc
    13681 atgattattg acaaatacat gcatttcaga tgcgtccttt acaagtaatg gacgtgcttc
    13741 gtctaagtag cgttccagcc attggatcgc ataatcacct aaaggaatga tccgctcttt
    13801 atctcctttt ccaactgtct gtaccagtcc aagagaaaga tgaagatctc ccaatttcaa
    13861 tccaatcaat tcactgacgc gcatcccagt agcatacatg acttccaaga ttgcacgatc
    13921 tcttatccct aacgtttttg tcgtatcagg tgcttcaatc agcttttcta cttctgtcag
    13981 agtcaatgta cttggtaatt tctgtgcttt cttcggcgta tcgatatgtt gcatcggatc
    14041 atgatcagtg atacgctctt gccgtaaaaa ctgatggaat cttctgagac ttgagatcat
    14101 ccgagtaaca gttgctgtcg cttttttttc ttcatgcaac ttctccagaa aacggatgac
    14161 taaaaagcga tcgacatcct gccatgaagc aattttctgc tcctgtagaa aatgcaagta
    14221 ctgttccaaa tcacgttcat agctttgtcg tgtattggcg gacaatcccc gttcaatatt
    14281 caagtagtgg agataatcgt tgatttgctc tttcataata atccccctca tgcctctcta
    14341 tcatatcaga taccgcttca ttctgatagt ctttttccat aatctgagca aagaaaaagc
    14401 cgtctagaca ctcagacgga ctggtttctt ttttcttttt catagcattc ctgacagatt
    14461 ccatggaacg ttagccgatg atcttttact aaaaaatgat aacgttcttc tactacttgc
    14521 tccacttcaa gtaaaagatc ctcttctact tcctcgatcg tgccgcagtt caagcatagt
    14581 aaatgatgat ggaaatgttt ggcgccttct tttctcaaat cataacgggc taatccatca
    14641 ttaaaactta ctttatcgac aattttcaat tctgtcaaga tttcaagggt tcgataaaca
    14701 gtagcaagtc caatttccgg actctttttt ttcactaaaa agaagatttc ttctgcagat
    14761 aaatgctctt tctcattttc caaaagcaca agcagagtag cttctctttg cggtgtcagc
    14821 ttaaaccccg cttcatgtag ctgctgtttt gtttttttca tcgccgaaat agcattcatg
    14881 accatttact caaccccaac aatttataat aattacaaat aaaaaaagat ataacactat
    14941 gttaattaaa attattataa gctagttaag aaaaacatgc aagggattct caattagatt
    15001 ttttgactag ttttgtcaca ccgttttctt gtgtaatcaa tccttgtttc aaaagattac
    15061 ctaatgcgcg cttaaatgct cctttgctga taccaaaagc tttcatgatt tcttctggat
    15121 ccgatttatc tgtaaagttg atttgctgat ctgcagaacg ttctaaaatg gttaaaatca
    15181 tttgtgcatc atctgatata gcttcatatg ctcttggctt caatgaaaga ttcagtacac
    15241 cgtctggtcg gacaccaatc actcgacctt ttatctgctc gcctagacga ggttcattat
    15301 atcgttcaga aggatggata aacccaagat agaaatcttc cgttaaaacg tacgtacctg
    15361 ttaatttcaa gcggtatgct gttcctatca catctttgtt tttcatttct tctgttccat
    15421 atttgcttaa agatttgaat attttttcat ctgctaaact gccccaaata cggtcttttg
    15481 catcaactct aagggaaatc atcaagcgat cccctttttt aggccatagc tctgtcattg
    15541 tcggcaattc atcaagagat acgacaaagt ctttatctgg aagaccgata tcgacaaacg
    15601 cacctaaatc ttttcgtgta gcagtaacga ttccaaaagc gtaatgaccg atacggcttt
    15661 taggaatttg tgtagtgatc cgattttcat gtttttgatt ttggtaaccg aatccttcaa
    15721 ctgcttcacc gattttgtgt tcaccttctg atttgcttaa gccaaaggtt tgtccgtttt
    15781 tttggacaaa gtagtttttt tcattttcat caataataat acctgtaaat atagttgcta
    15841 ataaatcgtt catttttttc tccctctata gtgaaaggtt ttcttaatac atttctttgc
    15901 tatcataaca taatgttatc tacttgaata gctgagcctt ggtttggaaa ggtgaaaaaa
    15961 ggagtatgac aacagttgtg tcatactccc ctttttcgaa taaacggtgt taaacggcag
    16021 gctcacagcc tctttcattt gcctaaaatt aattgctccc atttcctccg aaccatccag
    16081 ttttacagtt gatggttacg atgtaaaatg gcaaagcact ttctccaatg cctttcatca
    16141 atgcagattt tgttgaagtg gcatatagat tataatagcc ttccccattt tcgattctgg
    16201 ctttttctaa tctgtaacct ccttcaacga tatatccacg ttggatacat gtagcaatca
    16261 ctttgctttg gacacctggt gcccacgtcc atgctggatt agatgcatcg gcaatatcac
    16321 ttgctctggc agatttgatt ggctgattcg ctgagtttga agaggaaggg gtcgaggatg
    16381 ccgcttcttg ctgtgctgct tgtgcgaccg cagcttgttg agcggcttga gctgcagctg
    16441 ctgcttgagc ggcttgtttt gcttgttctt cagctgcttt tttcgcttct tctgcttttt
    16501 tcttttcctc ttcttctttt ttctctttat cagtgagcat cttatctact tgtttcaatt
    16561 gttcattcaa ctgagcagat agatctgtat ttttcacttt ttctactgct tcttttgccg
    16621 tcttgtattg gtcgcgtgtt gctgaatcca ctacttttcc gtctttaaag actatagctg
    16681 ttttttcttt agctgtttgc aattcagcat attgattttt agcttctgtt tgtgcttgtt
    16741 gaatcaattt tccaaaatct gtgttatccg tttcgattgc ttggatctct ttatctgctt
    16801 tcaacttgat gtcatctgct agatgatcat cgacgatggc aggtgctatg aaccactcat
    16861 tcactttttg gatatctcgg atcttagatt ggatatcttg gtaagttgtt tctaactctg
    16921 aatatccttt ttcattctta agactggata aatcattttt tagttttgat aaatcttgat
    16981 gaatcatatc tgcacgaata aattgatggt gatcatctgt ataaaaggca gcaagtttct
    17041 catgaagttc ttccatttgt tgctgtcttt ttgcttctgc tgctacttcg gcttctactt
    17101 tttgatgatg gtcataataa gcccagcttc ctccaccgag tagaagtact gctgctaaaa
    17161 cgagataagg tacttttttt gattttttct tttgcgcttt atctggatct gttttttcta
    17221 agtttgattc ttgatgtgtt ttttcagtat ctggcacgat tgttattgat ttcgcttctg
    17281 cttcaaacag cttaggctgg ttctcttctt tttctatttt tgcttcaaga tcagtaccct
    17341 ctttgcttac agattgattt tcagcatcgg attcactatt tatttcatcg ggctctgttg
    17401 actttttgtc tgtgttttcg agtatttctt ttttctctgc ttccggcagt ttattcgttt
    17461 tttccttttc taattgtttt tcagtaaata cttcagtttt ttctgtgata tccgttttta
    17521 cgtcttttat ttttactgtt tctttacctg tggcgttttc tctatcagag tctttttcag
    17581 tttcttgttc cttttctggc tctactttgt tttcctgtgc aattttttca ctgatcattt
    17641 tgagcagctc tttcgcgtgc tcttcttttg tatcttcacg atgtgctttg atataagcgg
    17701 atagtatcga attttcttcc tcattatcga cgatttcttt cagttcagct actcttcttt
    17761 tttgttttga ttcaagcgtt tcttcttgat tctttcctga ttcttccgaa gtctcatgaa
    17821 cagttgcttt cttctgttca tttttctcta tattagttac ttgatcgtga gcaggtggtt
    17881 cttcgtcttc tggttctgct ttttcgaata attccattac agattctaga ggtaaatctt
    17941 tcaattccga ccattcgatt ggatcgttta attctgtatc aggaaagact gcatcttcag
    18001 ttgatttatc ctgcatagct gcatctgtat ttgtttcttc aattgattct tttatttgct
    18061 gatcttctgc agttatttga tgaccgcagt ctggacagat agtattctgc tccatttttt
    18121 tcgatccgca atttggacat tttttcatca cttagcgatc ggctccttta ctaggtttac
    18181 gctaccattt aatctatcat attctatacg tcacgccaat agcttatttt taggatttac
    18241 ttaaaaataa tgaatgaatt tccttcctat agaaaaaaaa gcttgagact gcgtagtctc
    18301 aagctttttt tcttttaaaa taaaccaaac agttttactg atttctcttc tggtcaatag
    18361 tccacgctta ttctaagaaa tcttttaatt gttttgaacg agaaggatgg cgcaattttc
    18421 ttaatgcttt agcctcgatc tgacgaatac gttcccgagt aacaccaaat actttcccta
    18481 cttcttccaa tgttctcgtc cggccatcat ctaaaccaaa acgtaagcga aggacattct
    18541 cttcccgatc agtcaatgta tctagtacat cttccaattg ttcttttagt aactcataag
    18601 ctgcgtgttc tgctggactt gttgcttcct ggtcttctat gaaatcacct aagtgagagt
    18661 catcttcttc accgattggc gtttcaaggg aaacaggttc ttgcgcgatt ttcaagattt
    18721 ctcggacttt ttctgttgga agatccattt ccgcaccgat ttcttctggc gtaggttctc
    18781 ttccaaggtc ttgcagcaat tgacgttgga tacgtatcaa tttattaatt gtttcaacca
    18841 tatgaactgg aatacggatc gtacgtgctt ggtcagcgat tgctcgagtg atggcttgac
    18901 gaatccacca tgtagcatag gttgaaaact taaatccttt gcggtagtca aatttttcaa
    18961 ctgccttcat cagtcccatg tttccttctt ggatcaagtc aaggaactgc atgcctcgtc
    19021 ctacataacg tttagcgata cttactacta aacgaaggtt tgcttctgcc agacgctgtt
    19081 tcgcttcttg gtcgccttct tcgattttca atgctaacgc tacttcttct tccgcagtta
    19141 aaagggagac acggccaatt tctttcagat acatacgaac cgggtcattg atttttacac
    19201 cggttggcgc agaaagatct tctgtttttg cttgttcagc ttttttctca gcactcttca
    19261 agctgtgaat tgatggatca ccattttcat ccaccacact gatacctgcg tcttcaatct
    19321 tttggatcaa tttgtccatt tcatctgcat tcaaagtgaa tggtgtagca agctgattgg
    19381 ataaatcatc atatacaact tgtcgtttgg gtttgttttc tttgatgaaa gctgctactg
    19441 ctgcttcata cgttttttta tctgttccat ttgccataaa agaaggcccc ccttgagtag
    19501 ctatttggct tgttttaact gtttcgttaa attgatgatt tcaatcgtca attcaagctc
    19561 aagctgtttg tttccagttc gtctggcttc ttgctgcatt tgttttttta atgttatttc
    19621 atcagctaag ccagatttgc tgatcacatc tagcaagtct tggatttctc gtggcgaact
    19681 ttcttctgcc accggtaaat attcgatttc caccaccaac cgccttaaat tttcatcttg
    19741 caaaaagtct aaaaactctg caaggttgaa ttcataatgt tgtgagacat atgcatcgaa
    19801 taaaaaataa acttctgcat atgcatcatg aataaactga aattctcgtt cttttaaaat
    19861 attacggaca gaaacttctt taaatgcacg atataataga atctgctctg ccttttctac
    19921 ttgcgtcaaa ggtctctttt tccgtgcagt ttcttgtctc gtaacctgag tgtgttgact
    19981 ttcctgaggt tcttgacgat tttgctgatt tgtccttcga agatcgcgca gttgtttttg
    20041 tatcgtctct ctgccgatct gaaactctgt tgacagttga gatagataca tatcttgttc
    20101 gattggtgaa acaactcggc taagttcaac tagtaattct tcgaggtatt cgatcttgtc
    20161 tttttcatta tctaaatttt tcccttgttt taaataacgt gatttaaaag taaagactgt
    20221 ttcgcgccca tgagccacta attcttggaa agatgcttct ccatacttac ggagatattc
    20281 atcaggatca agcttttctg gaacgactac gacagaaagt gctaatcgac tgttttgccg
    20341 aagcaattca atccctcgat tggttgcttc aaaacctgcg ttgtctccgt catagcaaaa
    20401 gaccaattct ttcgtcagct tttccatttg ttggatctgt tgagctgtta gacttgtccc
    20461 catagaagct aatccagttt tgataccagc ctgccatgca gcaatcacat ccataaaccc
    20521 ttcgaacaac aaaatttctc cgtttttccg gatatcgctt cttgctttat caagattaaa
    20581 taaaacttgt cttttattga acagttctgt ttctggacta ttcaagtatt tgggctgatc
    20641 tttttcctgc cctttttcag gtgcaagcca gcgtcctgaa aaaccgatcg tctggccttg
    20701 agaattacga agtggaaaca tcactctttg ataaaaacga tcagacatac ggccatcatc
    20761 atgcgtgaca aacaatccag agcgttctaa caattcattt gaaattgatt cattcttgaa
    20821 tacttgctga agaaaagaac gctcattagg tgcaaaacct atgttgaatt cttcaattaa
    20881 ttctaaagac aacccacgac tttgcaaata ttctaaagct ggctgtccag cttttgtatg
    20941 caatagcatg tgatgataga tttccgctgc tttttcatga gcagcaatca gtttccccgt
    21001 agcagattca ggattttgga cagctatagt acgctgacgc cattgatctt ctaacggtat
    21061 ctgttcgaag tctgccactt ttaccactgc ttctggaaaa cttagacctt ctagttcttg
    21121 aagaaaagta aacacgtttc cgcctttacc acaaccaaag caatgaaaaa tctgcttgtc
    21181 ttctgcaaca gaaaaagacg gtgtacgttc ttcatgaaaa ggacacagcc ccaagtaatt
    21241 tttaccagac tttttcaact ggacatattg tccaatcacc tcaacgatat tcgtttgact
    21301 gcgtactgtt tcgataacct cttgaggaat ccgttgagcc attttttcac cccctgctct
    21361 attgatatct tttgggttta acagaagata tttcaggaga ataaccggta aaaaatcgca
    21421 ctaactgaaa tcagtgcgat tttaaaggac acaattatac atgtttgatt gtatcatatt
    21481 tcattgcttt ttcaagtata acacatttct atctcattaa gcatcaattt gctactcttt
    21541 tcagtaactg attttgaata tcagccttcc agtacaatac tcgaagaaca atatttacga
    21601 gcatgaatac aaagaagtat cctacgctct ctcccaaccc taagtttact tccaaaattc
    21661 catggaacag cattgcagct acatatatcc ctacgatcgt cgttactgct aggaagatgc
    21721 gcaatgggtt gaagggataa caagctttta caactgccat gcaactgatc ccaatcagca
    21781 agtaatacat caaagtagta gtttcagcat ttccccatgc gaatgttttt ccaagtagat
    21841 acaccgcaat gatattcact actacaagca aggcatttgg taaagcatta ataagtgctg
    21901 taggcaaata acggtaagtg atttttcttt tatcttgttc aaaagataaa aagaaggaag
    21961 gatacccttc aatcgctaaa tcaatcagcg tgatttggat agggataaac ggaaatccaa
    22021 ttgctgtaac ggcacatata atcgataaaa taaatgaata aatcgttttg ataaaaaaga
    22081 tgcctgagac tttcgtcaca ttgttgacca ctcggcgtcc ttcaaacagg acttctggca
    22141 atgtagtaaa atcagagtcc aacaatacca gattcgcaat ctgacgtgtt gctccatcac
    22201 cttctgccat agcaatgctg caatctgctt ctcttaacgc caaaacatca ttcacaccgt
    22261 cgcctgtcat tgcaaccgtt ctgccgcttt ctttcaattc atttaccagc aatttctttt
    22321 gctgcggact cactcgtcca aaaaccgtat agcgatgagc agcttctcgc acttccattt
    22381 cttcagtaat ttgagaaaga tcgacatacg catcataatt cggtaatcct gcacgtctag
    22441 cgatattgga gacagtaaaa ggattgtctc cagaaatcac tttcagatcc acaccttcct
    22501 catgaagata agctagtgtt tcttgagcgt tttttcggat tggatcatcg atttcaaaca
    22561 gagcaaccgg ctcaacaaat gctggttttt cttcgttcaa ttgctgattt ggagcgatcc
    22621 ccaacataag tacgcgatag ccattcgctt gggctgtttt tagactgtcc ggaagccgat
    22681 cttcttccac caaacgttca ggcgctccta cgtacacgac tcccagttct ggaaattcca
    22741 tcgcgcccca tttgcgatca gaagaaaatg cgactttgtt tgtcacatca taccgattag
    22801 aaagctcaaa ataatctctc atagcccgca tagtgatgtt gttatcactg ctttctgcca
    22861 gatacgtccc cataatttct gggatggctt tctcgtacag cggatgtagt gcttctaccc
    22921 gctggatact cattttccct tcagtaatgg tccctgtttt atccaagcat aatgtatcga
    22981 catgggccag cgtttcaatt gaatacatgt cttgaacaag gattcgtttt tttgccagtt
    23041 tggttacccc tgtcgttaat gcaatactta ttagcaatac caaacccttt ggaagcatgc
    23101 ctaacaaagc tgctgcagat gcaataacag aaattttgat agaagcatcg cggatgaaca
    23161 gtgcttccaa aaatagtatg atccccaaag gaataatcac gaaactagtg aatttggata
    23221 ctttgcgaat cgaatctaca agttcagaac gaatagcttt gtgagtcttt gcctcgctag
    23281 tcaagcggac agcataatta tctgcaccta ctcggataac ttcagccatg acagaaccgc
    23341 ttgtcaaaaa gcttccagaa agcaattcag ctccagtttc tttgacaatc aaatcagatt
    23401 cgcctgtcaa aagagcttca tttgcttctg cccgtccaga tataacctgt aaatcggctg
    23461 gtatctgttc tcctgctccg atttttacca aatctcctaa taccagctct ttagtagaaa
    23521 tcgattgttc tttaccgtcc cggatcacta gtacttctga ttgggaaaca atcgataatt
    23581 tccgtacaag atttcttgca tgtatttctt gataaattcc aataacgata ttgacgacaa
    23641 taattgctaa atacgccatg ttggaatacg cacctacaaa taacagacaa atcccaatac
    23701 caaagttcag aaaattgaat aacgtcaata tattatcgct gaatatttgt tttgtacttt
    23761 ttgatgcatc ttcctggtag tcattttgct ggccagaagc cattttctga actacctctt
    23821 gctgtgtaag tccattcatt ttctttttct ccattttccg ccaactttca aaaataatca
    23881 cgtgtttaag tctagcgtgt tccaagatta aaaacaactt gtttttataa aatttataga
    23941 aaaacacacg aatgatttta caaaaaagat gccaaccttt ttgtttgaat cacccgtgtg
    24001 ctgtttttat tatcaatcta tctttactta tattgttcct ccaaacggct catccaccaa
    24061 cctagtgctg taccggctat aaaaagaaca ggacaagcta gtaccccagc aactcccaat
    24121 cccgcgtaat cggtaggaat gatcataatc gttgaagcaa aaactacacc taaaatgaaa
    24181 tggaatagct tgctatatgc ctttgagaaa atgtaatcca tgatttttga caatccaaga
    24241 acacaaagaa tcccaccaat tccgatcggc acaatcactt caagtcgtac ttctttaaat
    24301 ccgtcagcca tcgctttata caatcccata tacaccaaaa aattagaagg gctcaatcct
    24361 gggacgatca tacccaaacc aatcaatccg ccggcaatca gccatgttcc aaaattctga
    24421 tcgacttgcc cgtcaaataa ttgagcgccg tataataaaa acaaataagc cagaacaaaa
    24481 gtaacaacca tgatgatcac atcagaagta tctcttcctt ttttccctgc ttctttccat
    24541 aacgcaggaa cagttccagc gatacatccg acaaaaaacc ataatatcgt tgtttcatac
    24601 gcacctaata aaaaactgac taaaaaagaa agtagaaaga tgcctgtcac tccgcctaga
    24661 ccaacaggca gaaaaaacaa aacattttct ttgaaatttt ttgtaaggtg ggctaaaaaa
    24721 gaaatcagcc gctcatacat gccaaagaca gctgctaatg caccaccgct gactcctggc
    24781 aagataaatc ctgaaccgat aaacattccc ttcacaaacc gtaacatcca gtctttggtt
    24841 gtgtacccca cttcttgatt ttccattttt tgcctttttt ccactatttg cgtactcctt
    24901 ctttcattta attttattca tgattgaaca tttcctgcta ttttacttaa agactttttc
    24961 ataggtctct attatttttt cattcatttt gacaatatca ggataaaaca tgttacctcc
    25021 attatgatag agatagccgc cattgtaaag caaggactgg atccgccaat atcggtattg
    25081 tttcccttcc tcatttccta aaagtgggct cagcacatct ttagaatacg cttctgctaa
    25141 ttctactgtg ttttctccgc catgattttt tacataggca atataatctt tcccaaaatt
    25201 atatgcttgg acagctgtcc ataaatcgca tccttgtttc tttgcttcta ctatcatttc
    25261 cgccaaatat ttgacacctt gatcaatact gtcagctgga ttatcaatga tctcagcttc
    25321 tccatgcaga ctttccgagc tctgcatgag atctgtccct tttccttttg attcggtcaa
    25381 tattatcgcc ttgatcaaat tctcgtagtt ttccatatga taattttttg cagctgttgt
    25441 tatttctatt tgatagcttt ccactcgttt taccgaacga taagttcttc ctcataaaaa
    25501 caacaccgca ccaataaccg tcagaatgat catgtaaaaa agaatacgga taatagataa
    25561 tcgttttcgc ttcatttcat cacctagtta ttttgacatc tttttttatc ttactatttc
    25621 tttatcttct tggctatttc ttccttgatt tctgtgtacg ccttaagaaa aaatgaattt
    25681 tcctgtattt tttgacatct tacgaaaatg atcgttgttt ttcagtaaaa acaattgccc
    25741 aatgactgat ataatcgtta tactttacac agtaggtgat tatgtgaaaa aagaaaagaa
    25801 atatgcaaaa atgccagatg ggagcgaaat ttactatgaa aagagcggtc aaggcttccc
    25861 tctcttttta ctgcatggca atgacggcag cggccgcttt ttttcagaac aggtccctgt
    25921 actcgaacgc tactataccg tgtatctagt agatagccga ggacatggtc gttcgacaaa
    25981 cgaagcatct atgttgaatt ttcagttaat ggccgaggat ctgaatacga tcatgttgct
    26041 ggaaaaaatc gatcaggcag attttcttgg atttagtgat ggagcaaatc tagcactggt
    26101 atttgccagc agcttcccta aaaaagttca tcgattgatt ttaaattctg gaaacacgct
    26161 tgttaaaggc gttcgttttt ctgccagagt catcagtaat attcattatg catgggtatg
    26221 gttactctct ttatttcgcc caagtcttcg caaaaatctt ttagttatca aacttttgct
    26281 gcatgacatc gggcttacag aaaatgattt aaaaaaaatc aactccccca ctttgatcat
    26341 cgtgggaaaa aaagatgtaa tcaagctaaa acattctttg tatatagcta aaactatacc
    26401 aaaagcttcc tttgtgcttg tgaaagaaca aggacatgaa ttagctagaa aagatcctga
    26461 acgcttcaat cgagaagttc ttcaatttct ttctgaaaca taactattag gaatagaagg
    26521 tgatttattt gttaaaaaat accatacaat ggctgaaaaa ccacctagga ctgttcaaaa
    26581 caatcttttt gatttctgtc attgtcatta ttgtcggtga attgatgtcc atcggtaaaa
    26641 ctctatctat ccagcaatta ggagaaacgt ttgccactat acctgtatgg aaaagcggac
    26701 taatgctatt gattggtctt atctctgtgt tacctatggt tggttatgat attattttga
    26761 atcggatgct tgaacaaaag cagaatcctc gttacctgtt tgagacaagc tggctgatca
    26821 atacgatcaa caatattgcc ggtttcggcg ggtttgttag tgtggggctt cgctctgaac
    26881 tatatggaca aaagaaagag agcagaaacg tgatccaagc attatcgaaa gttttcttgt
    26941 ttttgatggc tggactttct atttacagtc tgctttcttt tttacttgta gtcttcacgc
    27001 cagttgctcc ttttttgaag caatattgga tatggttgat cggcggcggt ctatattttc
    27061 ctgtcgtctt tttatttact actttcaaaa agaaaggatt ccttggtggt acctcactta
    27121 aaactcaagg acagctattg ctagtttcat tgttggaatg gaccggtgtc ctgtttagtt
    27181 tcctttctgt tggttattta atggaaatcc ggattgatct gtggcaaaca attccattat
    27241 tcattgctgc ttcagtgata ggaatcgtgt ctatgattcc aggagaaatt gggagtttcg
    27301 atgtaatgat gattatcggg ttgtccgcta ttggtgtgcc aagagaaata gtcgttgtgt
    27361 ggatcttgct ctatcgcctg ttctactaca tcattccgtt tttgattgga atcgtctttt
    27421 tcttcaaaaa tatcggttcc acttttgatc agcgttattc tggtatccct aaacaattag
    27481 caacagaaat tgcgcataaa atcgtggttg tcttattata cttttctgga atcatgctag
    27541 tactttctgc cactatcccg caagctttta cagagtttcg ctggcttcat agtttgaacc
    27601 cattgaaatt tcattttatt atccaatttc ctagtatact attgggattt cttttaatca
    27661 ttatgggcag agggatcgca gcacgtgtga aacgagcata tttgcctaca atcttcttga
    27721 ttgttctagc tttactttat gttttattaa gtgattttag tttcacaccg gtggttttct
    27781 tgtctattct gcttctgatc attcttgctt ctaaaaacga attatttcgg gaacaattga
    27841 tctattcatg ggagtggcgt acgatcgatg gaatcattat tggtgcactg tccttgcttt
    27901 acatcgttat tggggtatac aatctgccgg atttccctca tcggcgtcac cattttattt
    27961 cctttttctt atttccttct gaaaagattt ggttttcggg attgttggcc atcatcgctg
    28021 ttagtttcat gatcgttcta tttgttcatt tccttcaagg agaaaagaaa cagattggcg
    28081 aagcctttaa tgaagaaaag gccctgaaga tccttacaac ttatggagga aactccgata
    28141 gtcaattgat cttcttaaaa gataagcgga tgtttgccta tgaaaaagac ggtgaaccaa
    28201 ctgttcttct ccaattcgct tgcttcaata ataaatgtat tgtaatgggt gatccttctg
    28261 gtaagaaaga agattttcca gaagcaatcg aagcttttat cgaagaaaca gatcgactat
    28321 gctatttacc agttttctac gaaacaagcg aagagattgt tatgattttg catgaattcg
    28381 gctacgattt cattaagatg ggggaagaag cttatgtaga cctgaatagt tttacaactt
    28441 cagggaaaaa aatgaagggc actcgtgctg tcttgaatcg gatcgaacga gaaggattta
    28501 catttgatgt cttacaacca ccattttcta ctgagcaaat gagtactttc aaaaatatct
    28561 ctgataattg gttgggttca cgaaaggaaa aagggttttc tttaggcttt ttctctgaag
    28621 attatctaca aagagcgcct attgcagttg tcaaaaatac ccaagaagaa attgtcgctt
    28681 ttgcaacgat catgcctact tacacgaaca ataaagtagg aacgattgat ctgatgcgat
    28741 atgattctaa aaaagcacct tctggcagta tggatttctt gttcttgcat ttgtttgcct
    28801 atatgaaaga agaacatatc caatggttca atttagggat ggcccctctt tcaaatgtcg
    28861 gaacttccag aaagagtttt ttacaggaaa ggattgcata cttggtttac gagtttggtt
    28921 ctcattttta ttctttccat ggattaagag aatataaaag caagtacgct acaaactggg
    28981 tctcacgtta tactctatat tctagagata gttggattgc atatgttatg attgctttgc
    29041 tgattattga taatgcgcca gttgagcaga cacaaggtag aataagtggt ttgaaaaaat
    29101 ggatacgaag aaagtattaa aaactgcata ccgatagatg aacactctca tgatgaataa
    29161 aagagactga agtaaaacga aagttcatgc ttctacaatc tcttcttata caattgaaga
    29221 acaaagagcg gtccaaacag aaatcctgtt tggaccgctc ttttatttta aacatttttc
    29281 attaccaaaa tattcgagtc gcgtttctta tgcttcgatc tctgtaacga tacctgaacc
    29341 tactgtccgt ccgccttcac gaattgagaa tgtcgttccg ttttcaacag cgattggatg
    29401 gatcaagtca acatcaatcg tcacgttgtc accaggcatg accatttctg tatcttctgg
    29461 caatgtgatt gttcctgtaa catcagttgt gcggaagtag aactgtggac gatagttgtt
    29521 gaagaatgga gtatgacgtc caccttcttc ttttgtcaac acgtacactt ctgctttgaa
    29581 ttttgtatgt ggagtaatgg aacctggttt agcaagtact tgtccacgtt cgatatcgtc
    29641 acgttggatc ccccgtaaca acacgcctac gttatcccca gcttccccgt aatctaacgt
    29701 tttacggaac atttctacac ctgttacaac tgctttttgt gtttcaggtt tgatccctac
    29761 gatctctacc tcatcaccga cacgaacagc accacgatca atacgacctg aggcaacagt
    29821 tcctcgacct gtaattgaga agacgtcttc cactggcaat agtaatggtt tatctgtatc
    29881 acgttctggt gttgggatat attcatctac tgtatccatc aattccataa tagcagcttc
    29941 agcatctgga tcgccttgca atgcttttaa tgcggaacct ttgatcacag gagtgtcatc
    30001 gcctgggaaa ccatattcgc tcaataactc gcgaacttcc atttctacca aatcgatcaa
    30061 ttcttcatca tcgactaaat caactttgtt caagaaaaca atcaggtatt ttacaccaac
    30121 ttggcgtgac aataaaatgt gttcacgtgt ttgaggcatc ggaccgtcag ttgcagaaac
    30181 aactaagatt gcaccatcca tttgtgctgc ccctgtaatc atgtttttca catagtccgc
    30241 gtgtcctggt gcatcaatat gcgcgtagtg gcgtttttct gtttcatatt ctacgtgtgc
    30301 ggtattgatc gtaatcccac gttcacgttc ttctggagct gcatcaatac tagcatagtc
    30361 ttgaggattt gctaggcctt ttttgcctaa tactgtagtg atcgcagcag ttaaagtagt
    30421 tttcccatgg tcaacgtgtc caatcgtacc aatgttaacg tgtggtttac ttctgtcata
    30481 atgttctttt gccataattt acaaacctcc taaataatat agatcactga aaaatttcag
    30541 ctctcacctt tttattatag tctttttttg actaaatcaa aaagaatacg tccgacttac
    30601 tttttgtaag attcgaacta agcttattat acgtcaatat tggtcaaagt caactaagag
    30661 cactcgtctg tcttatacgc gaaaaaagta ccttttataa ataaaaaaat gtgttttttg
    30721 agaaaaactt caagatagtc cttaactttc ttttgaagca ataagaacaa aatgaggaaa
    30781 agtttaaaat tcagctgttg ccaacaactt tcaatagacg aaatcttcta tttcgttaat
    30841 aataaggaaa gaggtgaagt acatgaaaaa attaattggc gtacttgtcg ttttaggcat
    30901 atttctcggc ggaagttttg cagcttatca ttatttttac ggcggcgaag cttattatac
    30961 aaaaatcacg acgaatggcg aaatgtcagc tacccaagca gataacggag agaaattcac
    31021 gacttatacc tacaagcaag cggcttataa taaagatggt gaaaaaaaac aggtgacgct
    31081 tcgcgaagaa agagaacatc cattaaagat gaatgcgtat cttaaactca aagtcaatcc
    31141 tcgtaaaggt gtattaagct gggaagaaat aaaggcttct gaagtgccta aaaatgcggc
    31201 agaaaaaatc gataattagt aaatggtctt aaaattttat tagataaaaa gaggctggga
    31261 cagaagcgtt taactccaag aaataagaag gagttgcttc tgcttccgcc gtttatacgt
    31321 gtttagagcg tgagacaaaa gtgttcttta cttttgtctc acgctctttt tttgttatat
    31381 tcgtcttttc cgatccttct cttgacacaa ttcatttaac tgatcactgg tacttgaaca
    31441 cctaatattc tagtcatttt tataaacgat tcaatacttc atccacattt ttgatcatca
    31501 cggatatcgt accatccgga ttattcacaa attcaatcaa atctgggttg cgatatacat
    31561 ctactggtac gatcagttcg atcccgtttg atagcttgaa tttttgtttt ccaaattttt
    31621 tctcagaaat ttcttgtact tcttttacag gaggtgcttc tgggacaaat ccttgctctt
    31681 gtacttcttc tttaaaagcc atttttgccg tgatgttttc cttgaagact ttttccgcaa
    31741 tcatctcatg atccaaccga cctttttctt ctatcgtatc atagacagct tctttcaaat
    31801 cagccatgat atcaaattct tctgtctcaa atttttttcc aagatgcttg gctacttttt
    31861 ggatcacttt tacattttct tctaaagaag gtgcaggaac actttcgatc actcttccag
    31921 aaaaataaag ctcttttttg ccagaaaact catatttttt ttcaattaat tcgtaggtcc
    31981 aatcagtcaa attcacagcg aatgcttcat ctgctttttg tgttttcgcc cctagaattg
    32041 ctcgattcaa aatcaagcgg ttgtcgatcc ctgcttcgtc tgcttcaaca aagtgagtgt
    32101 aagcctcacg ataattgact ttcaataaag ataagtacat cactgtatct aattcataca
    32161 agacaacaaa tacatctgca ctaggtgctt cttcactttc ttggtagata tcgaaccacc
    32221 gctgaacgat tgcttcactt gcttccacaa aattttcttg agcgatttta agtgattcaa
    32281 cgatcatgct ttcttctgct agttgtccag tttttgtttg agcagaagag attttttgga
    32341 tcttcttttg aagaaaatca cgaatatatt cttttgtcag atccagctct ttttgtgaaa
    32401 agactggaga accagtttct ctgtcaataa tatgcagaat tgcttttttt aaatagatat
    32461 ccattttctc attcccttct gtcttagttt acggaaaaaa aatcaaaaat accagaatca
    32521 aaatcatttt cttttaaaca aaaatttcaa gagtagaaac aaaatggatt ctttttttcg
    32581 aaaaatgcgc tacacttata gttgaacgaa taaaaaagga gctgaaagta tgaattcatt
    32641 aacaagcact tatcgtctat caaatggtta cgaaatcccg gtagtaggat tcggcacatg
    32701 gcaaacacct gatggggatg tcgctgtttc ctctgttaaa gaagcgctgg ctgcaggtta
    32761 tcgccatatc gatactgccc aaggatacaa gaatgaagaa agcgtcggcc aagcgattaa
    32821 ggaaagtgga attcctagag aagagatatt cttgacaaca aaattatgga atgcaaacca
    32881 cagctatgaa cttgtgatgt cttcttttga agaatcattg aagaagctcc aaacagatta
    32941 tttagatctg tttttgatcc actggccaaa ccctgttgct tttcgtgata attgggaaca
    33001 agcaaatgca gatacatggc gagcatttga agaactgtat gaagcaggta aaatcaaagc
    33061 aatcggtgtg agcaatttct taccccacca tctagataca ctagcaaaaa cagcaaaaat
    33121 tatgccgatg gtcaatcaag ttttccttgc accaggcgaa ttacagacaa ctgtagttga
    33181 gtatgcaaaa aaacatgata tgatcctcga agcatatagt ccattaggca ctggtaaaat
    33241 cttcgatgtg cctgaaatga aacaaatcgc tgaagcacat gacaagacga ttgcacaagt
    33301 tgctttgcgt tggtcgctgc aacacgaatt ccttcctctt cctaagtcag tgacaccaag
    33361 cagaatcaaa gaaaatactg aattatttga ttttgaatta acagaagaag aaatgaaaca
    33421 aatcgatcag ttagatggtg tagtcggcaa agcaaaagac ccagatacta cccaatttta
    33481 agtcgaaagg tgattttatg gatccaatcg aacgcttgaa ttctctctcg gaagaagtta
    33541 cccagacttt tcattccgat tttgtctttt tgatcgatgc agagaaaatc caacattttc
    33601 ctgcaagaaa ctggacacat gatcaaatca tcgaagaact gaaaaaacgg ttcgatcatt
    33661 cgctaatggt caaaccctgg cacgaacatg aagtcattta ttcacctgaa ctacctgttt
    33721 ttgccttgat accgaaaaaa tagaaagaat ggaacggatt atgtatatat acataatccg
    33781 ttccattttt tatttttctt tcaaaaaacg ggaaaatacg caaatttttc tgttgtaatt
    33841 tgcgtatacg caagtttttt tgcattactc cttttcattt ggctgttttt ttcttataat
    33901 cgaaagggta tgagcgaagg agagaacata tgaagaaaaa acagaaacaa aaattattaa
    33961 atcaattccg tccttcattg gatggtgtaa gaggacaatt attccgttct ctagaagaag
    34021 agagcttgcg acgttatggt ttgccgttac aagtcatgct tgatcccaaa aaccgtcaaa
    34081 tcttaacgat cggattagct gggaaaacaa atgaagatac acggatcaac gtgccaatcg
    34141 atgacaactt caatactgta ttaaagagaa ttcgttcagg agaaaacggg attttcgaac
    34201 gattccgtga caatcttctt attgaaatcg tgtcttactg gaatgatcaa cgattgaaaa
    34261 acgatgaacc aactgcgcaa gctgttgcga caccagttac agaagaaaca gtcagtgtgc
    34321 cagaagaaaa aacggaaaaa ccaaaagcgg acacaactga aaatacacgc tcaactgata
    34381 cgaatgccgc tttaagtttt gctgattttt caaaagccgt tgctgagtat cctaaatttt
    34441 acacagaaca aaatgaacat gaagtagtta ttaatgaaaa aaatgctgat gaacctcgta
    34501 aattagcaac tatttctatg actactgaaa atgagttcgt tatcgaaaaa gcactcgaac
    34561 ggaaatacaa agtcaaattg actttgattc ctttgatcga acaatttgca gcgacagcga
    34621 ttactgatcg ataaaaattc tatttgtcat aaaaggctgg gatttaaaat cccagccttt
    34681 ttagtcatat aataatttct acagcaagta aaaagaaatt ccttctaaca tcaggctcaa
    34741 atatcagctt gacctgtcca acaaatcacc tatgatccta caatgttagg cgacttctct
    34801 tctacctgaa gatatcttgg agttgcctga tttcttaaga tgcctaacct taactataaa
    34861 aaattctaat aataaacata ttttctgata gagaaaaaa
//
LOCUS       DAIGSZ010000026        34784 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.026, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000026 DAIGSZ010000000
VERSION     DAIGSZ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.026"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..2269)
                     /gene="esp"
                     /locus_tag="NOB31_001313"
     CDS             complement(<1..2269)
                     /gene="esp"
                     /locus_tag="NOB31_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HCI0973531.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDI"
     gene            complement(2886..3191)
                     /locus_tag="NOB31_001314"
     CDS             complement(2886..3191)
                     /locus_tag="NOB31_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973532.1"
                     /translation="MLNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDA
                     KISSYLFFLIHDEFMDYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3336..4541)
                     /locus_tag="NOB31_001315"
     CDS             complement(3336..4541)
                     /locus_tag="NOB31_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HCI0973533.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKDFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTGNLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5235..5621
                     /locus_tag="NOB31_001316"
     CDS             5235..5621
                     /locus_tag="NOB31_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0973534.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5719..5910
                     /locus_tag="NOB31_001317"
     CDS             5719..5910
                     /locus_tag="NOB31_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973535.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6424..6756
                     /locus_tag="NOB31_001318"
     CDS             6424..6756
                     /locus_tag="NOB31_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0973536.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            6666..6869
                     /locus_tag="NOB31_001319"
     CDS             6666..6869
                     /locus_tag="NOB31_001319"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI0973537.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKMLNR"
     gene            7053..7208
                     /locus_tag="NOB31_001320"
     CDS             7053..7208
                     /locus_tag="NOB31_001320"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HCI0973538.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLTDHHITHSMSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7484..8824
                     /locus_tag="NOB31_001321"
     CDS             7484..8824
                     /locus_tag="NOB31_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0973539.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(9065..9472)
                     /locus_tag="NOB31_001322"
     CDS             complement(9065..9472)
                     /locus_tag="NOB31_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HCI0973540.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
     gene            complement(9467..10671)
                     /locus_tag="NOB31_001323"
                     /pseudo
     CDS             complement(9467..10671)
                     /locus_tag="NOB31_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180763.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
     gene            10797..11015
                     /locus_tag="NOB31_001324"
     CDS             10797..11015
                     /locus_tag="NOB31_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973541.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            11036..11671
                     /locus_tag="NOB31_001325"
     CDS             11036..11671
                     /locus_tag="NOB31_001325"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0973542.1"
                     /translation="MVRHLFVDFQWSPEKISNRLKHEHMDFSISFITIYRAICNDLFD
                     TEPLSHGNKGLIRSLHHRGKTRHTKNHVESRGKICLTHSIHGHPKSADDRSDFGHWKA
                     DIVAGKTSGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEVLNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11864..12103)
                     /locus_tag="NOB31_001326"
     CDS             complement(11864..12103)
                     /locus_tag="NOB31_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973543.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12127..13650)
                     /locus_tag="NOB31_001327"
     CDS             complement(12127..13650)
                     /locus_tag="NOB31_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HCI0973544.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            complement(13668..13790)
                     /locus_tag="NOB31_001328"
     CDS             complement(13668..13790)
                     /locus_tag="NOB31_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HCI0973545.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            complement(13820..14803)
                     /locus_tag="NOB31_001329"
     CDS             complement(13820..14803)
                     /locus_tag="NOB31_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCI0973546.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14827..14976)
                     /gene="rpmG"
                     /locus_tag="NOB31_001330"
     CDS             complement(14827..14976)
                     /gene="rpmG"
                     /locus_tag="NOB31_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI0973547.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(14997..15374)
                     /locus_tag="NOB31_001331"
     CDS             complement(14997..15374)
                     /locus_tag="NOB31_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973548.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15406..15585)
                     /gene="rpmF"
                     /locus_tag="NOB31_001332"
     CDS             complement(15406..15585)
                     /gene="rpmF"
                     /locus_tag="NOB31_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCI0973549.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15600..15869)
                     /gene="rpsN"
                     /locus_tag="NOB31_001333"
     CDS             complement(15600..15869)
                     /gene="rpsN"
                     /locus_tag="NOB31_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCI0973550.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16392..18158)
                     /locus_tag="NOB31_001334"
     CDS             complement(16392..18158)
                     /locus_tag="NOB31_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0973551.1"
                     /translation="MQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINMVP
                     AFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLRMQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18118..19872)
                     /locus_tag="NOB31_001335"
     CDS             complement(18118..19872)
                     /locus_tag="NOB31_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0973552.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLK
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(19982..20551)
                     /locus_tag="NOB31_001336"
     CDS             complement(19982..20551)
                     /locus_tag="NOB31_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HCI0973553.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20569..21984)
                     /locus_tag="NOB31_001337"
     CDS             complement(20569..21984)
                     /locus_tag="NOB31_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0973554.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(21995..22663)
                     /locus_tag="NOB31_001338"
     CDS             complement(21995..22663)
                     /locus_tag="NOB31_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCI0973555.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22794..23378)
                     /locus_tag="NOB31_001339"
     CDS             complement(22794..23378)
                     /locus_tag="NOB31_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0973556.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCIDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23713..23943)
                     /locus_tag="NOB31_001340"
     CDS             complement(23713..23943)
                     /locus_tag="NOB31_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HCI0973557.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKRF"
     gene            complement(23958..24905)
                     /locus_tag="NOB31_001341"
     CDS             complement(23958..24905)
                     /locus_tag="NOB31_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCI0973558.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(24905..25747)
                     /locus_tag="NOB31_001342"
     CDS             complement(24905..25747)
                     /locus_tag="NOB31_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI0973559.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            complement(25880..26605)
                     /locus_tag="NOB31_001343"
     CDS             complement(25880..26605)
                     /locus_tag="NOB31_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI0973560.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGGTA"
     gene            complement(27066..27380)
                     /locus_tag="NOB31_001344"
     CDS             complement(27066..27380)
                     /locus_tag="NOB31_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCI0973561.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
     gene            complement(27396..28991)
                     /locus_tag="NOB31_001345"
     CDS             complement(27396..28991)
                     /locus_tag="NOB31_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HCI0973562.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            complement(29014..29904)
                     /gene="iolE"
                     /locus_tag="NOB31_001346"
     CDS             complement(29014..29904)
                     /gene="iolE"
                     /locus_tag="NOB31_001346"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HCI0973563.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            complement(29921..30946)
                     /gene="iolG"
                     /locus_tag="NOB31_001347"
     CDS             complement(29921..30946)
                     /gene="iolG"
                     /locus_tag="NOB31_001347"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HCI0973564.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            complement(30970..31977)
                     /locus_tag="NOB31_001348"
     CDS             complement(30970..31977)
                     /locus_tag="NOB31_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0973565.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            complement(32090..33250)
                     /locus_tag="NOB31_001349"
     CDS             complement(32090..33250)
                     /locus_tag="NOB31_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HCI0973566.1"
                     /translation="MNIQLKMPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTG
                     HLQKIKELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTA
                     KVVAVLAANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKM
                     MMKDLVFMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEA
                     MKKILNTLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPH
                     GISNAMLLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLS
                     IPTIRDYGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            complement(33326..34780)
                     /locus_tag="NOB31_001350"
     CDS             complement(33326..34780)
                     /locus_tag="NOB31_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010825391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HCI0973567.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
BASE COUNT        10889 a         6932 c         5319 g        11644 t
ORIGIN      
        1 aaatatcttt acttacagtt actgctaaat cggtcgtgcc tacagaacca tcttggtaaa
       61 caattttaat aggaattgtt ccagtaatcg gctccgattc tcctacacct ttagctggag
      121 tgaatgtaac aataccagta tttgcatcaa cacttgcatt accgaagtcc ttattataga
      181 catctaaaat tgaaaaggca tctttagcta aaggaacatc tggtttatca aatgtaggtt
      241 ttccactttg aactgtcgtt tctggagttg ttgttatagg tacgtatgtt gcatcatttt
      301 ccatagcttg agaagctttt acagcaaact ctacatccac gtcgaaagtt cgatttccga
      361 tcttaacagt tacaatacct ttcgtactat cagtaacgtt agaagtatca ggctctgttt
      421 tccatgaata ctctgcatct tcaggtaagt ttttattatt ccgaattgat tctttagcat
      481 ctggtttaaa tccaactacc acggtttgtt tatcaaccgc ttttggtgat tccttaataa
      541 cggttgaacc ttcttctggt ttatcaaaac ctggagaaac gatttggatt tttaattcat
      601 ctttcgcgat taatttactt gaatctacac ccgtaaattc aaattctaca gtatctgaaa
      661 ttggagcccc atctttttca tttggagcga tagttttttc tgctaataca gtaccttctt
      721 tatcaacaag ttgggctttg tgacctgttc ccgctaactc gtggatgaat actttcccct
      781 taactgttgt gtcaacatca tatacttctt ctaattcagg tttcccgata tatggattcg
      841 tgtctccgct ctcttcttta tcgtcagggt ttccatcacc atcaatatct tgcaaataat
      901 aataacctgt tccataagtg ttctggatta attttttatt cgtatccgac aaccaagaat
      961 caaagatgaa atcttcacca aatggtttat tttcttcaac ttgtgctgtt gctttcatat
     1021 cttctaagat ttcatctaat ggcttagtca attgtaaaac atatcgaata acgactggac
     1081 gtggacttgc attagcaaaa tcaataagtt tggtaagatc attatcagta attgaaccta
     1141 caccataatt ttcatgatct ttgcgccgtt caattgctaa atcagccact tttttccctg
     1201 attcaaaaga aacatcatat gttactttgt cagcctgaac catgtgcatc tgtatacccg
     1261 ctacatatgg aactaatcgt tcatcaattt tgtaattagc ataccaaggc gtgccctttg
     1321 cggaagctga atatgagaaa ttataatttt tcgttaactt atgatctaag attatagctc
     1381 cattagcacc tgtggatcct gaaccatctt ttgtttgagt attaggttcc tcatattttg
     1441 cacttactga tccatgttta aactggtcag gattattttc agatacatct aagctattat
     1501 agaaatcatc tgaatctgtt aaaaagtagc ccgtactatc aatacctggt acaattttat
     1561 catcgtcttg atgacttacc aagtagattc gatacattaa acgatcggtc ttgagattgt
     1621 ctatgcctat ctctttaaaa atttcatcta agctcttttc aaacgtaatt accccattag
     1681 gagcagtttg tgtatcagtt gtttcagccc cagcaaataa tccatcactt gcacgaatat
     1741 aattgacctt ccaaatattt gtaggtctac ccagcgaatc attaattctt acaaaggtcc
     1801 gtctagaaga tccaattcct ttctttggat cgacctgaat tttttctaca tatttagcta
     1861 atcgttcatc taattgaaga cggatttccc agtttttagt tgatgctgca atattatgtt
     1921 ttccgtaaac ttcaaatcca attgtattgc cttttagtgt gtctccagtt agttcttgag
     1981 gactaaattg taaatccgaa aagttataat ttttcgtata accaggattc tcctgaaaag
     2041 tattccccga agctactttg tcacctactt gtacggagct tatcgctgtt tcaagtgggg
     2101 tgcttggaga aatttcatct tgtgcttgaa ctagttcagt tgttcccaag acaagaccaa
     2161 caccaaccaa aacagatgca accccaacac ttaatttttt gatactgtac ttcaatactc
     2221 gtttctttgt tttttctaga aatactctct tattattctt gctaaccatt attcaaatca
     2281 actcccttaa tagttatttt cttagtaaga ataaaagata aatctgatac gtattattca
     2341 cagaatagga atcttactaa acttatgtta actagtttac ttaaagaatt tcatgcacat
     2401 tacaacaaaa aaagtacatt tcttcatgtt tttttcggat atttgtgctt tttaaccatt
     2461 cagcagctga aaacatataa aaagatatgt atgtattctt tctgaaatta agttcatttc
     2521 tatgcgatga agcatgtttt caaaatatta ctctttctta gattaaactt cagagtattc
     2581 aaatagcgga ataaggagcc ttatcccgca ttactgaatg agactgtgac ataagtaaaa
     2641 aggtgacttc aaattccttc ttcggaattt gaaatcacct tctttataat tataaagtat
     2701 cggtttcaca gcattcctga atgattccta gaatcttaaa cgaatgattg gagttatcaa
     2761 cattttttca ctcgttttta gcgaaacaaa aaatgacatt tgtcacagcc tcattaaatt
     2821 attgattctt tttctttata attgaattgt ccatatttaa agtgtctagt actctacatg
     2881 aataattaat tgctttcact caaatactta taatctatta acttgtagtt gtttaacttt
     2941 tctgaaaaag ttagacccac gtaataatct tcccagcttt ctctttcaat taactgatcc
     3001 aatttttgat aatccataaa ttcatcatgt attaaaaaga ataaataact tgatatttta
     3061 gcatctagct taatcagatt aaataatgtt tgcttaaaat tgctaccatt aatatgactg
     3121 atagattctc tagcttcttc acataaactt tttactttat taattactac tttgtcatat
     3181 tcatttaaca cactattatt accattactt agacgctcag attctacgaa acaactcaaa
     3241 tcagaaattt cccaaaaaat tttttgttaa aatccaattt cctcaactcc tccaaactac
     3301 gtaaatgata tagtctcata ataaaataaa acctctcagc taatgttgtt gaaattatcc
     3361 actaaaccta attgatattg cttaggagat acacctgcgt actttttgaa tactctcgaa
     3421 aagtgtgaag aatctgaaaa tcctaaacct aaagaaactt cactgatagt atggtttgat
     3481 ttcaacatta ttttagccgt agaaattttt cgcttagaga tataattata aatcgtaata
     3541 tgcatttcat tcttaaagct ttctcttaat ttagtttcac ttacagaaaa ataattagct
     3601 atttccttta cagtaattct tttatagata tttaagccga tgaattgaac gacagaagaa
     3661 attaagggag aaagatgctc tatcttagtt tttccgattt ccttagtata ataaacaatc
     3721 ccagaatccc tcacttttaa gacctcaggt aacgatacag ctaattcgtt ttcttgtatc
     3781 aaagcatctc tactttgata cgcttctatt atatccattc ctaatgttat agacgtttgt
     3841 gctaactttt caaaaacaat gatagaataa tttttttcag accgaatcgt atctccacta
     3901 acacttggaa ttattccatt actcagatta aaaaccatgt tttctaaatt tcgaatatct
     3961 ccatttttaa catattccag tattttattt tcataaagaa acagatatat ttctggatcg
     4021 taattttgtg ataacagatt atctattttg atttgctcga tagttttact tagatttcct
     4081 gtatattcaa ttaacggttc atggaataga tcttctattt ttccagtaaa aaaataatga
     4141 actaaaatca gaatatctcg aatgtctcct aaagaataca aagtcaaatt ttgcaatgaa
     4201 ttatagagtc gttctctatc agccattgca acattcaaat tgttcatttt tagtttaaaa
     4261 aaatctttat caatattatt tgctctaaat ggaccaaata agtaatatct ggttttaaac
     4321 atgtatagaa gaaacatctc attaaaatca ccagtaaaga aatggaaatc tttagttttt
     4381 ttaatattat cagttagtaa ctttttataa tcataaaaaa aataagtagt tctatctgag
     4441 cgatactctt ttataatact gaattcggaa ttaaaaacca cgataggtaa ctttaaacaa
     4501 acatgaagag actttaataa gacttcttta tctgaaaaca cttttgtttc tctctttcct
     4561 ttctacatca ttaaatagta ttttatacgt tatctaaaat actattcctc tgtcaaaata
     4621 agctaactta cttcattata aaatatccac ttatcgcttt catgtatatt ccaccgtaaa
     4681 aagtacattt tatcaccgag aactcatcat ttttcatcat gatgaatact atttacatat
     4741 atctagttca aagacaataa ttattatgat ccgttattat ctaagcacta tacagataat
     4801 aggaattttt cgtttctaaa tactccaatt tgggaatcca ataaaaattt tcgttcaaat
     4861 acgtgtctat tcgaactctt ttctagttgt taattatgaa gggggaagaa ataaaaaata
     4921 caatctatac acgaataaga atattatcca aaaggaggtt ttagaaaaga tttattatac
     4981 gtaaaaagct caagacattt tcttagccat aaggacatgt ttgatattta agaagatata
     5041 tgaattttct tttctaagta taaagataac tatccattat caactaaaaa aacatttttg
     5101 aaaataaaca tcagcagtcc tatcaatgca tgtgagctta tagaagttat tcgcagcgca
     5161 gcataattgc attagcttct tttcgtgttt tttgcctctt ttccctttaa atcttaatgg
     5221 aggaggtgtg caatatgtca gataacgacg aacgcgtaaa tgcccagttg attcgattct
     5281 ttgaaaaggt cattttgaac accgctaata cttattataa aaaacaagaa gaaattcaaa
     5341 aacatgaaca acttgatcaa ctcccaccat atttgtttac taaagatact ataaaattta
     5401 aacaaccgat taatgtttta aatgtgactc tccttgttga agatataaaa ttagcaaaaa
     5461 tccttccttt gttgaaagaa cctgaacaaa tttttcttat cgaaaaattt atctttaata
     5521 aaactgataa agaaattgga aaggttctgg gtattacaag acagggtgcg acaaatttaa
     5581 aacatcgact ttacaaaaaa attcaaaaaa tgctggttta atatctgcat aataactaat
     5641 tttgtatgct tctttgctcg tcctcctcct tccccaaaaa ataaatagat tataagttca
     5701 tgggaagaag gtaaatttat gaatacttta aaagaagatt tcattttagc aaagaatgga
     5761 aatgaagaag cagttgtggc cattctcaaa agatttagcg ctttggtcca taagcaatcc
     5821 tggagaactg gaaaatatga tcaagattgt tatcaagaat gtatgcttgc aatatatcta
     5881 gctatctcga aattcgaaat taaagaataa ctcaactaag ggagtctgtg acataagtaa
     5941 aaagatagtt tcaaatttcg aacaataaat ttgaagccat cttctttata attataaagt
     6001 atcgatttta cagcgttcta taatgattca tagaatctaa aacgaatgat tttaattatt
     6061 aacgtttttt aattcgtttt tagcttaaaa ataacttttg tcacagtctc actcctaaaa
     6121 ttactttatt tacgtacgaa gtgggcagga ggtcgaatcc agaactgggc catggtactt
     6181 caacgaggac ttctcctcta gaattgaaaa gcatgcgatt taccttccgt aacgacggta
     6241 gatttattca actatgtgtc caatcaaaat ttgtctgatt tcaaaaatag tcaagagaat
     6301 tttggttgtt aaaaactctt atctatcaac ttccacagtt tagttgacaa accctgatac
     6361 taagttgggc tatgatacac ttttcttgac tatcagttac gttaccggaa ggaatgaact
     6421 ctattgaaaa aaacatatga tcgtaaattt aaactaaaga tttcacagga tatccttgag
     6481 aaaaaagtaa ctaccaagaa aattgctgaa gaatacaata tctctcgtcc aacaatttcc
     6541 cgatgggttt cagaatatcg tcgatacggg aaaaatgctt ttgctggaca aggaaaaaga
     6601 ttacctgata aagcagattt ctacattctt gaacaggaaa ataaacgact aaaagaggaa
     6661 gacgagtgtt ctacgaacac aaagatcgat acggatctcc agggatcact caaaaacttt
     6721 acgatgaagg aatcgaaatc aataaacgtg ttgtagctgt tcttatgcgt gaaatgaatt
     6781 tatgcacaag aggatttcat cgacgcaaat cttctcatgg tagagaaaaa acaatcaaag
     6841 aaatggtaaa aaaaatgttg aatcgataat ttgaacagaa ccaaattgat gctgtttggg
     6901 tgacggatat tacttacatt ccatgtaatg acggtcgcct ctatttgtcc acctatattg
     6961 acttagcaac tcgtattcta cgttactata tggtggattc acacatgaaa aaagagattg
     7021 tcgtccgtcc attacaaatt tattaaggag aattgcctac ggtaattcat tccgatagag
     7081 gtagccagca tcggtctttt atttatcaag agctgttgac cgaccaccac atcacacatt
     7141 caatgagcca aactgggact cctgttgaca atgcagtaat tgaagcgttt catcgatcaa
     7201 tcaaatgaga attaatcgac tccaacaaat ataaaagtaa aatagagatg aaggtgttaa
     7261 tccaagatta tttagaagac tactacccaa acaaaagaat ccatacaaaa tttatgatga
     7321 ctccttgaca atttgaagcg aagaaaataa gggatctata atatctagtg ttggtgacgc
     7381 cttctgttgc caatactttt tcttttttct aataaacgca aacagacacc ttgaaatcct
     7441 ttagaataaa gtcgacgaaa accattcaaa ggagtgtttc aagatgtcct attcagagtt
     7501 taccaaagag ttactagata ttctagacct aaatcttacc tttcatgaag atgcctttcg
     7561 caaagagcgc attaatgacg aaacatgttt tgtttttgat ggcacattga cctatcaacc
     7621 agaggaatgc ttccattgcc actatcaaaa taagcaaacg atcattaaat ggggctggaa
     7681 aaaagtatcc atcttattga atgatgtcag taactacaag accattgtgc ggattaacaa
     7741 acagcgcttc aaatgtaaac actgtggaaa gactttttta gcagaagatt cagttagcga
     7801 tcgtcgctgc tccattgccc gcagagtcaa acaagccatt cttgagctat taagtgagcc
     7861 tatttctatg tctttgattg cacgtatgaa gcacatttct ccgaccactg tcattcgaat
     7921 acttcgcagc cttcggccta aaaccgtttc tttgaaccag ccgttaccag aagtggtgtg
     7981 tttcgatgaa ttcaaatcgg tgaaaaacgt ctcgggagcc atgagctttg tcatgatgga
     8041 cggcaagacc catcaactga ttgatattgt ggaaaatcgg caactcaatc ctttacgcga
     8101 ctatttcttg cgctacccta gaaaagtccg tgaacaagta cgtctagtgg tttcagattt
     8161 ctatacaccc tatcgcacat tggtgaaaga gtgttttccg aatgcccgaa tcgtcgccga
     8221 tcgctttcat attagccaac acatcggtcg ggcctttacc aaccaccgaa ttcaagtaat
     8281 gaagaccttt aaaaaagggg atcgtcggtc gaagcactta aagaaatact ggagactact
     8341 tcaaaagaat gcgtgggaat tgaatggtca gcatcgctac tggcgtccgt catttcgaga
     8401 tcatctgaca gaagcggaga tagtcgatcg gctattatat tatgatgact ccttaaagcg
     8461 aggctacgaa gtctaccagg tttttctttc cgctatcaga agacaagatg ttcctgaatt
     8521 cgtcgcgctc ctaaaagaag actacaagga gttgccagag cactatcaac cagtgttcac
     8581 gaccttcaag aaatatcgaa cagaaatcaa acgagcgttg cgagttccct attccaacgg
     8641 ccctatagaa tgtttgaaca accatatcaa agtactaaaa cgaattgcct atggctttag
     8701 aaactttcaa aactaccgag aacgaatctt tttatatcga ggaaaatatt tcaagaaaac
     8761 taagaacact acccaactga ctaaagccag aacaacaaca cggctagaca agatagctgt
     8821 ctagccgtgt gagtatctcg attattctat tgaatttctt caccaacact cattgacgaa
     8881 gagccaaaat aagtaatcta accgactgtt aactaaacca ttgcaggtcc cgttaaagat
     8941 acttgtgcct gttgtcaccg cttctttttc ttgtccacaa gcgcttaaca cacttaataa
     9001 agcccctgct attattaata ataatatctt tttcttatta aaaacctcct catctatttc
     9061 cagattagta aatgtagtaa tctttgcttt cttttttctc aatactaata actaacttat
     9121 ggggtaaaca aatactcgtt tgaccgggtt ttgagatcca tccagttcta accgcgattt
     9181 gatcaggact attatcttct ttaactcgaa ttcttccatc tttaatctca acaatattat
     9241 attgtccctt cgcaggatga taattcacga gtttatgatt gatcttatcc aaatcgaagc
     9301 gatccatttc cttgccatca atttgaacga tggcatattt gatagcatct tcagttgttt
     9361 cattctcctt ttctatagag aatacaaata agggaataaa agagggaata atcaaaatgc
     9421 caataattat gacatcgcct atcttgacac cagcttttct taaaaatttc attaacgata
     9481 tctggctaaa catattagaa tttttccatg gaaatggtga aatttttcgg aaattatctg
     9541 cattaagaga atcagttaaa caaccctcaa gttgttcctt aatacattgt tgatccatct
     9601 tcataccaat aaaaactagt ttattaatgc gttcaccaaa caacggatgc caggcttcct
     9661 tcaattcggg tttttttgta taatcatttg acactcaatt ttaggtaaac tagctaccca
     9721 ataatttaat gattcaatac ttttatggct acccgatgtt tcaaagatcg tcgaaaaatc
     9781 actatgttgg gcaaaccaaa gaaacccttt tgctcttgta atattgccag gaaaattttt
     9841 atccgtaaga tgggcaaatt tttgtgcgtc aaggagtaac cgatttcgat agataaaact
     9901 tgagatacca tattcttctg tttcaggaat atgattttga tagccaagct ctaactcttt
     9961 gaaccagccc attgaatagg aagtctcatc tatattaaaa agatttgtat ttagaatttt
    10021 cgataagtct acttcacctt taattgtcct aattattttg gcattggact gtaacttagc
    10081 aattagaccg ttaattttgt aaatcgtctt ggttgacact aagtcactat tatttaaaag
    10141 taatatgtta caacactcga attgatcaat taacaagcca cgaatatcct gttcttcttc
    10201 aactacatta ccttcagctt ttctttcctg aatcttttca cccgtttcga aattatccca
    10261 aaaacgtttt acatccacta ctataataat ggcaccaatc tctaatcgtt gggtcaaatc
    10321 aatgtctaaa gggtttttag ctaatataat tgcttgaata attggaattg gtttgctgat
    10381 tcctgaagct tcaataacaa tttgattcaa gtcagaaaat tgcactaatt gatctagttc
    10441 aacaatcaaa tcttcgcgta atgtacaaca aatgcatcca ttcggcatcg aaacaagttt
    10501 ttctccagtt cttttaaaac ctttcttgtc gactaatacc ccatcaacat ttacttcccc
    10561 tatgtcattt acaatgacag caatttcctt tccgtgatca ccgtacagaa tatgatttag
    10621 aagtatcgtt tttcctgaac caagatagcc agttaagatt gtaataggta ttttttcata
    10681 gggaacctct ttctatacct tgaatttaca ctttaagtgc aacacataaa aatgagtcat
    10741 aatcgatatc caactagtat aagtttgtcg agaacactcc tagaaggaaa ataattatga
    10801 gccagtattg tcatcttact atactcaaac gagaaagaat ctttctgctt cacgaagaag
    10861 gattttctat tagtataatt ggcaacgaca ttcagcatag cccgtttact attttacatg
    10921 aactgagaag aaacaagaaa aaaactaatc accttccaaa gcggaaaaaa attatgctta
    10981 tcgaagaaaa aaatgcggac gttatcacat tctaaatgat ccgtgagttt ggtcaattgt
    11041 tcgtcattta tttgtcgatt ttcagtggtc gccagagaaa atctcgaatc gtttgaagca
    11101 tgaacatatg gacttttcaa ttagttttat cacgatctac cgtgcaattt gcaatgatct
    11161 tttcgataca gaacccctct cacacggcaa taaaggcctg atccgttcat tgcaccatcg
    11221 aggaaaaaca agacatacaa aaaatcatgt cgagtctcgt gggaagattt gccttactca
    11281 ttcgatccat ggccatccaa aatccgcaga tgatagaagt gattttggtc attggaaagc
    11341 cgatattgta gctggcaaaa ctagtggtac ttgtttagtg actttgacag acagaaaatc
    11401 atgcttcctt ttagcaggaa agaaggtccc cagaaagaaa gccgcttatg tgagcgagaa
    11461 aatgattgaa cttttaagca gtattccaaa tgaggcggtc aaaacgatca ctccagatag
    11521 aggaaaagaa ttctccaatc atttcgcagt tacagaagta ttgaataata tgccctttta
    11581 ttttccagat cctcatgccc ttggcaacaa tgaacaaatt aaaatacgaa tagactcatt
    11641 cgagaatact tgccaaaatc gaaagagata gctacggtag ataactcaac gataaatcag
    11701 atgattgaaa aactgaataa cagacctaga aagtgtttag attggagaac accttatgaa
    11761 gtcttctttg ataaagtgtt gcgcttgatt tgacaattca agaaataata aaaagcagat
    11821 caaatccaaa taagggaaaa atgatctact ctggtattat caattaattg gccaagctat
    11881 tatgccgttt tgctaaacgt ctacttcttc cagtattgac cttgataaaa caacaatcag
    11941 gatcccgttt taatactcta tgaactgtgt caatactaac atgtaaagtt gcagcaatat
    12001 cagctaatgt actcccattt aatctcattt gctttgcaaa ttgataacgc cgataagcat
    12061 caatattctt ggaatccata gacaataata cttttcttac catgtatttc ctccaaagat
    12121 tggattttaa tgggccatca tttcttgagc aatctcatgc tcagataatg aagctggata
    12181 gaaagtaggc caattatgca tttcattata aagtttttct tgactttctc caccaaagaa
    12241 aatatggaaa tgctctgcct tacttggtgc aattccatga tcgctaaatt gaatatattt
    12301 aaaacgacca gcacctgcat catcagtttc aaaattaaaa cgaacaccac ggtttccttt
    12361 ttcataattc aaaattttgt atccaacata tttgtatgtg tattgatgat gttcaccgtt
    12421 gactacaaaa tcaatggtgt tgtctttaat gttgatagta tcaatatctg tcttatagcc
    12481 agtagtataa taatctttgt actcggcagc tgtcatgtct ttattgagtt ttgctttgta
    12541 atcgaaaact tcatccaaaa ttccatcttt taacaacgga taaacagatt gccattcgcc
    12601 tgtataatca ctcaattcgc gatccttcac atcggcatct ttaaagtacc cattagcaac
    12661 tgtcttttca tccttcgctt ctttttctgg aactacctct tcaccagcaa ccatagttgt
    12721 tttctctaac gcttttagat tgtcttccat tactgaaaca taatcttcac cattatccat
    12781 ttgttctttt gtaagacttt caagaggatt caatacttcc aattttatcc cagcttcatt
    12841 ggccaaagtt tttgcgattt tatcattagc attcttttca aagtaaatat aattgatctt
    12901 atttttttta acatactctt ttaattcagc taatcgacca gaagatggct cttcttcagg
    12961 acttagtcca gcaataggaa cttgtatcaa tccataatcc aaagctaaat atccaaaggc
    13021 tgcatgttgt gtcacaaaac ttttttgttt cgcttcttta agactagtgg tatagtcagc
    13081 atccaaccgt ttcagtttag tcaaatactt ttcagcattt gtctcaaata cttttgcttt
    13141 tttcggatac aatttaacta actgatcctt gatatttgaa acttccttaa ttgccatttt
    13201 gggtgaaacc cacgtatgag gatctagttc atgatggtga tcttcttctc cgtgatcatg
    13261 atcttcttct tcactacctg gcaataaaat catgtctttt gttccttcta ctacattagg
    13321 cccagctttc ttccaacttt ctttagcttt tggtacccat gattccatgt tttcgttatg
    13381 atatacaaaa acatcagcat catgagcttt tgccatatcc ttagctgagg gctcatagtc
    13441 atgaggttct gatcccgctg gaaccattaa atccacgttc gcttcatcgc cgacgatgtt
    13501 tttggtgaaa tcatacattg gatagaatgt tgttacaatt tctaattttc catctttatc
    13561 attcgatact tttgcatcat tagtgctgga gcaagctccc aataatccta gagctgctat
    13621 cccaataagt cctacactga ttttcttcat tctttttcct tccttaatta tgctaatttc
    13681 ttcattttat tttgtttatg ttctttgata atttttaatg ccctttttct agttttgata
    13741 ttcgggcttt taagtcgtcg atatgcacta gatatatccg ttttctccat tagaaattac
    13801 ccctaatcaa tacttatcat tatttgcttt ccgccagtaa tttatcaaaa ctctgtttga
    13861 tcctttcttc atccaacatt tttccaatta gaataatagt ggtttggtct ttttgtcgag
    13921 tggtgtattg aaaattaacc tgttcgttta ccccttgtat ggcaactata aaatcttgat
    13981 cttgcaaagc aatcaatcct ttaaaacgat acaggctccc ttggttggtt aaaatcagcc
    14041 ggtcaattaa ttggaataaa aaatcttttt ttatgtcttg atctgaagtt aagagaattg
    14101 atttaaactc atgttcttga tgatgttgat gatagtgttt gccattatag tgattttctg
    14161 atgaatcact ttcaaaaact aagggatgat tgaatttttc caaattataa aaatcctttt
    14221 tttgaatcgt ttcactatgt gtgaacattc gaatatcgga taaagggtta atacttttga
    14281 tttctctctg taattttttt agtgcagata aattcaagtt ttgttttcta gacacaaaaa
    14341 tgcgatctgc tatgacaagt tgcttaaggg cttgtggttc tctttcaata agttcaaaac
    14401 tgtcactatc aataacagtc aataaactat cgatatatac tcttcctctt agttgaggcg
    14461 ctgttaaaag tgtttgaatg attggttggg gatctgctat acctgtagtt tcaatgatga
    14521 tttgtgaaat tggttgttga tgttcttcta ttgtttccag taaagaaatc aatattgcta
    14581 ataaatcact gcgaagactg caacacatac atccattatt tagttgtaac acccgttcct
    14641 cgctatgaac taataatttg tgatcaatcc caacttcacc aaactcattt tcaattataa
    14701 taatttcttc cctggggtag ggtgagactt gcaaggcttg attgattagc gttgtttttc
    14761 cagcccctaa aaacccagaa acgattgtaa ctggtatgcc cattttgtca cctttttacc
    14821 acttagctat ttcacttctt tgaaaattgc ccgtctgcgc aattttggcg aatacttttt
    14881 taattctaac cgttcagggt tattccgttt atttttgctg gtgagataca gacgttctcc
    14941 agtttcgaca cattccaaaa taatattttg acgcataaat cttcctcctt caatacttat
    15001 cgatcttcaa gatatgcttg aatttgttgt gcatcttcaa aagttaactc gccagattcc
    15061 aattgtgaaa ctaaattttc tttcatatca acaggtatct cccaataacc atcaatacat
    15121 tgaaataact cctcgtcata ctcttcaaaa attggataga ttcttaaaaa atcatcaaat
    15181 gataagcctt ggtcctcata gtaatctttg actaatccat tttcaattgc ctgttgggtc
    15241 ggtaaacccg tttcagtaat aattcctctc tctaccatcg aacgataaaa agtgcattta
    15301 tctagcgatt gctgggtcgt ttcaagataa tactttaatc cttcttcaac taaaggtggg
    15361 taaataattt ccattttgat tccctcctaa aagttatata ttaaactatt ttgaagctcc
    15421 tttaattact ttctttccat tatagtaccc ttttaaagat acatgatggc tacgtctata
    15481 atcaccattc gcttcgtcaa atgaaatttc tggttttact acagtttgat gagttcttct
    15541 taaccgtttc ttcgccttag atgtttttct tgctggtact gccatgatat ttcctccttt
    15601 taccaacttg ctttttttac tccaggaatc aacccttgat gggcaagttc tctaaactta
    15661 atacgggaca taccgaactt tcgcatatac cctcttggac gaccatccgt ctgatcacga
    15721 agcctcagac gattcggatt tgaatctctt ggcaatttag cgagagcggt gcgatctcct
    15781 gcggctttta attcctgacg tttatctgcg tacttttcaa tcatcgccat ttgtttcttt
    15841 gctttagcaa ttttcgactt ttttgccata tacctttata ctccttttat tttgatttag
    15901 acatctcaaa tcgtaatcgt tacgttttga cactgatact ttaccaacaa gagttgctct
    15961 tgtcaacaat aaataacatg aaataaaact catatgaata gataactatt tgaaaacgaa
    16021 tttatcggta catagagata atcaaatcat ttaaaagaat atgcagttta agctctgaaa
    16081 aataagaatt cacttttatt agtccaatca aacacaaata ccgttttaag tagcttttcc
    16141 tctacttaaa acggcaatat gaaagaaact ataacttttt attcaatctt ttatgtttaa
    16201 ctggtttatc gccaattttt taaaactttg attattcctt atattataag aatagacatt
    16261 aagtgaacta attcaatcat actgattctt tcgtgtattc aaaattagat gctgtttaat
    16321 aaaattattc tttttgaaaa agaattataa ctatatccca aaaattgtag gttaatttaa
    16381 agcctatttc atcatcgtga ttgagcttct ttttcataga cgaatttctc agatagttta
    16441 gttttcttta tgagattttt gtatatttct gaccttcgat acaactcact atgagtacct
    16501 tgatcaacta tttttccttg atccatcact acaattttat ttaccttttc aatagacttc
    16561 aagcgatgcg atataattag tactgtctta tcttgtatta aacgatttaa actttcctga
    16621 atacgttttt cattttccgc atctaaactg gcagtaattt catctaaaat taaaattggc
    16681 gcatttttca aaaaagcccg tgctatggat aggcgttgtc gctctcctcc agaaagtgaa
    16741 cttccgtttt ctccgaccaa tgtatgataa ccgtcaggta gtttttcaat aaagtcttcg
    16801 cagttagcta aacgagctgc ttttttcact tcctcatctg acgcttgact atttccaata
    16861 cgtatatttt ccaaaatact tgtattaaac aaagttacct cttgaaaaac aatagcgatt
    16921 ttgctaaaca aagaagctgg agatacacgt ttaatatcat acccatcaat taaaatacag
    16981 ccttcatcat aatcatacag tctagacact aatttcaaga tactagtttt cccggaacca
    17041 ctagcaccta ctaacgcagt cacttctcct tgtttagccg taaaagagat atgatctaaa
    17101 attggggtat tgttatcata tgagaaagag acatctcgca actcaatgtc aaaagatttc
    17161 agaggactat ctgatccctc ttggatactg gtttccttca tagctctaat tcgctgtatt
    17221 ttaggagcta aataaaatat ttcaagcact gcttctttca tagaatcgaa ggaatccttt
    17281 atttttattg cggctagtaa gtaaccaacg acgtagagta tagtcacttc acccgttaac
    17341 agtaagtgaa cacctactag aatgactact gctaaactaa catatgagaa aatagaggat
    17401 aaggccatga ctgaaaaagt acttaattct acctttaaat gaatcctttc actctcttcc
    17461 atttttttga aaagtctgtc ttgaactttt ttagatagat taaagctatt aatctcttgc
    17521 tgcaattcta tagtttcttg aaattcttcc gagttttctc tcaaagtatc gtaatattta
    17581 gtattggctt tcgtttggga tttctttgat aacaagatta agacaaaact aaataacgtt
    17641 ggcaaaataa cagctaatcc cattttgaca ttaccaacca aaagcatcac tgaaataaaa
    17701 gggaaaaaca gagccatacc gccggcttta ggtattgcat gactcatcgc atgctcaata
    17761 ccttcaacgt cagacatgat agtttgagat aaatctgata aattatgttt tgaaaaatag
    17821 gataatggta aatttgacaa atcgtctgca atttgcattc ttaaatgcgc actttcttta
    17881 taagtactat tatataagtt ttcatactcc ctatctaaca accaatacat gaaaagcaaa
    17941 gtaacgaacg atactgtaaa ataaagccaa ggcggcttta cattttctaa aactaattcg
    18001 tctatcagca tcattataat gaatgctggt accatattaa tgcagtatac aaaaaagcta
    18061 gaaatagatg ctttaaccaa atcttctgcg ccctgattag ttaaagcgaa tttgttttta
    18121 taaaaacttt tcattgtcaa gcctccaatc atttgcattc tcataattag tgaccaattg
    18181 tttatacact tgatgtttag ccattaattc attatgattt ccacgttcta ctattttccc
    18241 ttctgacaag acaagaattt catctacaga tttaatgctg gataatcgat gagctatcat
    18301 aataactgtt ttttctttca tcagatgttg aaaagccttt tgtagttcat actcattatc
    18361 tggatcaata gatgcactgg cttcatccat aataacaatc tttgcatctt ttaaaattgc
    18421 tctggcaata gctatacgtt gtttttctcc tcctgacaga taaactcctt tactaccaat
    18481 taaggtatgc tctctttcgg gaaatttttc taaaatcgat tcgcaaccgg ctaatcttag
    18541 cgcgtcaaat actttacttg ctggcgcttg aggatttgct atagaaacgt tatcgtaaat
    18601 actctgattg aatagtttcg tatcttgaaa gacaaaagca attgtgttaa taattgtgtc
    18661 ttttgaatag tgatttaaag gcttaccacc aattttaatc tgtcccttat ccacattgta
    18721 gaaacctgaa attagtttag ctatcgtact ctttccgctt cctgattttc ctactaatgc
    18781 ataaattctt ttttgttcta aaactaagtt gaaattttct aaaacacact cttctttgta
    18841 tgaaaagctg acattttcaa atgcaatgtc acaattttta atctgtgtct cgttcccata
    18901 ttttagttgg tcttgcttca tttctaaata aagggagtct agtgtttcga ctgcatatct
    18961 tgcttcaaac aagtgcatac ttacatacat tattctcatg aaagaaacaa aaataattcc
    19021 acttaaaaaa aacaacatca acaagtcaac agctaatatc ttgggagtgg taagagaagt
    19081 tataaaaaag gttataggaa ctatcaaaat gcaaactatg ccaaaaaata gccattgaaa
    19141 aagaacaaaa ggtgttttcc cactcaaaga atacttatat gcaaacttag cataatcgtt
    19201 aattgcttta ttcaaggctt taaatgatgt tactttagca ccaaatatct ttataacttg
    19261 aattcctcgg atatattcta ccgtttcaga gcttaacaca tctaacgatt cttgatattt
    19321 ttgaataaaa tttgtattct ctgtcatttt ctttaacaag aatacaccaa ttactaacat
    19381 ggcgattaga accaatccaa ttttaaaatt aatgaaaaag cctaaggcaa ctgataaaac
    19441 aggtgttact atggcttgag cactatctgg aatcaagtga gcaattgcca tatgtgtttt
    19501 agccgcgttg tcatcaattg tctttcgaat atatcccgaa gaatttaaat caaaaaaacg
    19561 aaaacttgct tctgttaaac cgctaattcc cttttttctc aaattagtct ctaagcgaaa
    19621 cccaaggata tgagaaaata agccagaaaa aatataaaat aaagctccta aagttaacca
    19681 agcaacagtt tgaaccgcat aactcttagc taaatattca tctcctacaa taattagaga
    19741 cttaagaaat ttgtaaatac tgtaatatcc atagactgtt aatacgacag aaaaatcaga
    19801 aaataaagtg gctaaccatc cgtagtattt cattttaggg acataactaa ataatttttt
    19861 gtatactttc attttttcct cccccgcatt caatttcttc tcttattcgt ttacaactgt
    19921 taatgctttc cgtaatagcg taaattagag atgtacaaac agatagaagg taaactacgt
    19981 tctatttttt gtattttttt aagacttttc ttccaatcaa tacaccaatc atagataaac
    20041 ttgctacaac taacactgaa atgattcccc atatacctac cgcatagtgg atcattgcat
    20101 ccattgttgc agcagattgt cctttatcta tccaatcttg acgaaaacga tctgtaaaga
    20161 accatatagg aatccactgt ccggcagcac tgcctaattg cattagagcc caagacgcaa
    20221 cttgaggaat tgctcgatca tatccaaata cagatagaat aatatcagct aagatcgcca
    20281 tactaatcga actgataaac caaggtaagt acgccccgcc cattaacgta aaaaataaca
    20341 ataaaacaat tgtgtaaata gtaaaaattc cttttctagg gtagttatag ctaatataaa
    20401 caaatatgat tccagataat aatccaaaaa tccctgggga tatgctgtga ccaaacgccc
    20461 caccaatact actaaccatt attgaaaaaa agtaaattac tagggaaata actgtagcta
    20521 aaccaataaa aatataatct tttgttttca tatatattct cctcaattct atttcgttat
    20581 gtcattaaaa atctgttcta tcaaagttga atcttctact ctaagtttta tatctttttt
    20641 tattccacca ttttttaaat aaataattct attgcatgtt ttataaagaa attccggatc
    20701 atgagtggct ataactactg cacccttttc ttttaagtct ttaataaggt cagcaatcct
    20761 ttccatatta atataatcca acccacttgt aggttcatca aatagaaata aattagtttt
    20821 tgacaatgaa gctatagaaa ccaataatct ttgtttttct ccaccggata aatcaaacgg
    20881 taattgatct ttcattttat aaagttccat tttttttaaa attttttctt gctgatcttt
    20941 actaactatt tcattcccca gggctaactc gctcctcact gattctgtga aaaattggta
    21001 atccatttct tgcattacta aaaacggcga tgacaaattt tttttatttt cgattatctt
    21061 tcctttggta gggcgaataa tcttcatgag tattcttagt aaggttgttt tccccacacc
    21121 gtttttccct accaaaccaa taacatctcc aactttgaca tcaaaattta tgtcttttag
    21181 aatattttca taagtaattt cttcaacttt taatacatct gcacttacct tttcgatata
    21241 gggaacttca atcgaactat taaaaatgtc aaatttcctt aatgcgttat tgttttcagt
    21301 ttttaacaac tgaatagttg tagtttttac agttctattt ttaacaaata gaacttgatc
    21361 aattaattct ttcaaatagt aaaaacgatg ttcagctata acaatagtaa atcctttatt
    21421 ttttaaatca caaagtaagt cagcaagttt cttagtcgct ttgaagtcca aatttgaaga
    21481 cggttcatcc aatataatta atttagagtt tagcgataaa ctacatccaa tagaaatttt
    21541 ctgccgttca ccacttgata gcgaaaaaat gtttttatct aatatatttg aaagatctaa
    21601 taattcagct aattcattga ttcttttatc catatgctct tttgtaaatc caaagttttc
    21661 catcgaaaat actaactcac tcgttgtatt tgttgtaaag aattgtcctc taggatcttg
    21721 acttacgtag ccaatatttt ttgatatact ttcttgtgtt aaggattgta gcgagttatt
    21781 ttcaaataaa atttccccaa ccaattttcc gtcataaagt cttggaataa gtccattcat
    21841 taactttaat agtgtggatt tcccactccc agaagaacca gtaatcaatg taagactacc
    21901 tttttttatt gaaaaattaa ggtcaacaag cgcttgttcc ttaacatcct tatatgaaaa
    21961 agaaacattg ttaaattcaa acaattcttt cacctcaaat caaaatactt aagaaaaaaa
    22021 tagtaacgga aaacaggatg atatagtcta ataagctcat gtttgtttta tagtaagaac
    22081 ttcttttcac aggagattct atcccctttg ttattgcatt agcggtcatt tcttcagcaa
    22141 tcatagttgc acgtataaga acgggaacta acagaaattc caaatattgc agaggctgaa
    22201 aaaaagacaa gcgaatgttt ctcattttta aagattcttt aatcattctt atttcagaac
    22261 gataagtcgg aaagaatctg atcactactg taatacttaa cattattttt ttcggtaaat
    22321 gtattttttc taaagaggat aataattcat tgctagtata gacactaacc aacaaccatg
    22381 agatcattac gaccggcaac attcgaaata caatatataa ggatgtccca aaaaatatag
    22441 taaaaaactc tatcttgata gcatcaataa ttttcattac taaaaacaga actgaataaa
    22501 tcaagatgaa ataaatacat gtctttattt tacgaaacat caatactaaa actgtagcaa
    22561 taatgaaaca ccccacttga aatatatttc cctttcctaa aaaaataatg accggaaaaa
    22621 aaatatttaa agtaatcaag gttaacggat tgatttttga cactctttca cctccaaaaa
    22681 ataagatcgc actgttatct taagctgata aaaatgcacc gttattcaga taacagtgcg
    22741 atcttatcaa aaagcataac tgagaacaat tctcaatgca agcttttttt taattaactc
    22801 agtaattcaa tccacccagg aacagaaaat tgatacaatc ttctggttaa tagcatagtc
    22861 ttttcttttg aatagctatg cttcaatata tcatagaatg tagcgtagaa tgagtaaatg
    22921 tagaagtgga tttcttcttc attaaagact aaattttgat tgatcattcc gatagtcttt
    22981 aacttatcta tacaacagac tgtctttttt gtcacaaatg atgtaatttt ttcaacaata
    23041 tcttgatatt tggttccagc tgattggaat aaaaccaaat cgaatatacg tttattctca
    23101 aaaatataat taataaatgg atctaattca ttgaagttct ctctccaact tttctctata
    23161 tctatatttt ctaagtttaa gaggtatttg gtaaactctt cattatacat attaataagc
    23221 gcattaatat gcggctgaat aatttcttca aataacgctt ccttagaagt aaaatgttta
    23281 taaaaagcac ccgtagttac gcctgcggtc aagcacagtt gccttatctt agtttgctga
    23341 aatcctactt tttcaaaatg gcttagtcca ctttctatta atttttggtg agttgtaata
    23401 taatctctgg tttctatggg tacttcctcc taataagatg aattaactat attatcttac
    23461 acaggacttg aagtttcaat cgttaacgtc tattactgaa ctcattcctt agagctaaac
    23521 taatgagaaa gagcaaaata actgatacaa aaagcaatcc tacaagaatt aatagactca
    23581 tctaaatcat tcaccttttc taaaataatc cgagaaagat ttaaaaaaat tatatccagc
    23641 tattaggata agtcctatca taatcactcc aatagccatt ttcttatcct ccctaaaaat
    23701 aaagcctttt acttaaaacc tttttttgta atcgtcaata aattttttcc ctttatcagt
    23761 taattgaaat cctatatcta aatagtcctc atatctaagt ttagtcagca tctcacttac
    23821 agatgctgga ctaacactta gaacttttgc taaatcatta ttttttaatt tcttttttct
    23881 ttttgataat tcctgaattg ctagtaaata aattagtata gtagttgttt taatttgtac
    23941 catacctacc ctccaaatta tttcgaaagg ccttcagcaa ttttatccag gttccatttc
    24001 atcatcgcat agtaactatc accatcttgt cctttttctg caattgaatc agtaaaaatc
    24061 gttgaataga taggaatatt ggtatctttt gatactgttt tcattggtct atcgtccaca
    24121 ctgctttcta cgaataagga gggaactttt gttgtgcgta atttttcaac taagtgtttt
    24181 atttgatctg gtgttccttc ttcttcagtg ttgatttccc aaatgtaagc agaaggcaca
    24241 ttatacgctt tcgagaaata tttaaagcat ccttcacttg taacaatcat ttttttatca
    24301 ttcggaattg aagcaaattt agatttagct tctttgtcta gagaatccaa tttttcaata
    24361 tacttatcta gattttcttt atagaatttt ttattatcag gatctttttc cgctaactgt
    24421 ttttcaatat ttttagcgta aataataccg ttttctaaat ttaaccaagc atggggatct
    24481 tccttccctt tctcactctg accctctaag taaataacat ctatgccatc acttgctgca
    24541 aaatagtctt tgttttcctc tttgttcgca ttttttacta attttgtaaa ccaagcattt
    24601 cctccagttt ccaagttaac accgttataa aaaatcaaat ctgcttttga agttttttga
    24661 acatcttcag gcaaaggttc atattcgtgg ggatctttcc caataggtac gatactgtgt
    24721 aaatcaattt tatcttttgc tatattttca gtaatatctg ctaaaatcga attagtaact
    24781 actaccttta atttttcgtt cgaagccact gtatctttgt ctttactatt tgttgaacat
    24841 gccccgaata taaaaagagc aatcaaaatc cccagacttc ccagtactgc tttccatttt
    24901 ctcatcataa ctttctctcc ttctttctta aaaatttttg ttttggtgag attagaaaac
    24961 taattacaaa taagaatgcc gctgttaaaa caatacttga tcctgctgct atgttaaaac
    25021 tataaccaat gaacaaacct agcaatgatg agcacgctcc gactgtcgcc gaaataaata
    25081 tcatagtttt taaactgttt gcatataaat atgctgtagc agctggtgta attaacattg
    25141 caacaattaa tatagttccc acactttgca tagctgttac tgctactaaa gttaatagaa
    25201 tcattaatag ataatgataa aaactgacat tcatccccat tgcttttgcc attaatggat
    25261 caaaagaagt gattaataat tctttaaaaa atagaacaac tgtaaccaac actaaaacag
    25321 aaacgccaat tgtaatccac ttatcaatat cttgtacagc taaaatattt ccaaataaga
    25381 tatgaaataa atccgttgag ctatttgcaa ctcctataag gataactcct aatgctaaaa
    25441 aagaactgaa agtaatacca attgctgtat ctccttttat tacactattg ctttttataa
    25501 aagtaataat gatagaagct aatagaccaa atacaatcgc accaataaaa aaattaatac
    25561 ctaaaatata agaaattgct actcctggca aaacagcatg agaaatagca tcacccataa
    25621 gagacattcc tcttaaaata ataaaacaac ctactgttcc agaaacaatc cctataacta
    25681 cagatgtaat tagagcattc tgtaaaaagt gaaagtcata cagaccatta ataaaatttt
    25741 gaagcatatt attccccttg tatattagag ttagggtttt aaccttccgg ttttgattgg
    25801 ataaccctat gaaccatcgt tattttaatt tggtattaac tcatttcttt tgagataata
    25861 tatttattgg attgagaggc taagccgttc ccccctctcc aataaatata gtatctccat
    25921 aggctttttt taaattctct tcattaaata cagattctac acttccgtga gcaattagat
    25981 ttcgattcaa aagaataata ttatcaaaat acttctttac cttgcttaaa tcatgatgca
    26041 caattagcac tgtttttccc tgatgtttca attcttttaa cgtatccata attattcgtt
    26101 cactaactaa gtctatccct acaaatggtt catctaaaaa tatgaaatcc gcattttgag
    26161 caagacatct tgctaaaagt acacgttgaa attgtcctcc agataattct cctatttgat
    26221 gattagaata ttttcccata tcgacctttt ccaaagcctt tgaaactctt tgccattctg
    26281 catttttaat tctttgaaaa actttcattc cggcatatgt tcccatagat acacattctt
    26341 ttacttttat tggaaaagta aaatcaatat cagctttttg ctctacatat gcaatcttca
    26401 ccagtttttt attgatatct tcattattaa tggagacctc tccctgatga gggataatat
    26461 ttaacattgc tttaagcaat gtagattttc cagcaccatt tggaccaata atacctgtta
    26521 aagcaccttc ttgtattttt aaagaaatct cgttcaatgc taaaaaatcg ttataacaaa
    26581 cattaagctt tttcacttct aacataactt tctccttcta aatgataatg attatcacga
    26641 tcatatggta tacaaaaatt atattttagt caaccctaaa ttttataatt tagatttttt
    26701 tctgttgttg aagattagga tgtcaaaatt atttgaaact actcgtatag taaatagtaa
    26761 gtaattttca aaacacgaag aaaaacaaaa agaaaaaagg aaacgccgaa gcatttcctt
    26821 tcagtgattt aatgagaaca acacgatttg acttagagtc tcaaaaagtc gaataggtac
    26881 actcatttaa gtgtctccat tcgacttttt ggggatgagc tggctattga ggtccgctta
    26941 ccctattgaa taaatacaag attgggtatt tctaataagt ccgcccttca tattggggtg
    27001 atcggggcga acatgccatc ttttcatata ccacctcctc gacactcaat aatcaaagat
    27061 tctcgttaat cttcttcgat gcttgcaatg atgttttcaa tattcatata acgaaaatct
    27121 tcttgtttga tataaacgat ctgagcggta catttttcct ttttgatgat ttcttttact
    27181 ttttcctcag aacgtgcgac ctgcggcgtt aaaagtaaaa cgtcatagtc tttataattc
    27241 agtttttctt caacgtttcg gatcgttgca taatctatct catacgatag atttttggct
    27301 ctgatcgttt caagcatttt tgatacgagc agcgacgcac tgattccggt ctcgcaaata
    27361 atcaatagat ccttatgcat aataccctcc tgtttttagc ctgcaaagcc aattggtgaa
    27421 aatgccacat aagttaaaat aacaatgact accaatgcta tagcagtcac cttggtgtat
    27481 ttccaaggct cgatatcgac ctttgtatcg aatgagttca acacaaattc tccatcaggt
    27541 ttcaatttgg aaaccaccat caaaatgata atgtccagaa cgaataatgc cgtcaaaaca
    27601 taaaggaaat ggatattttg gaaaagcatt tttgatagtg catacaagac gatatgcacg
    27661 gcaatcgtcg tttttgcccc aaaagcagtt gctttttttg aataaaaggc aaagagaatg
    27721 atcacgagca gcggcatgtt gtatagtcca ttgaattctt gaacgaactg atacaatcca
    27781 gccggtgcaa aagaaatgaa tggcgctacg ataatggaga taatccccac aacgaccgtt
    27841 actgttttac cagcacgagc gatttgctta tcatttgctt tcttattgat aagcggttta
    27901 taaaaatcca gtgaaaacaa ggtcgatgtc gcgttcaaag ctcccgcaaa tgatgataag
    27961 atcgcgccaa agataacagc ggcgaaaata ccaaagatca ttttaggcaa tacttcactg
    28021 actaaaaaag gatacgcgtt atctggattt gacattaaac tatcgccaaa aatattgcga
    28081 gcgacgatcc ctggaaagac aaggaataac gcacctaaga ttttgaagac gccgactagg
    28141 aaagcgccct tttgtgcctc agctaaattc ttgccggaca atgctttttg gacgatcatt
    28201 tgattggtac accagaaata cagattgtta aacagcatcc ctgtaaatag tgtcggccat
    28261 ggaacaacag ccgagtcgat cgatcccaca gagttaagca gccatggcgt gtttaccaca
    28321 acgtgttcga tcccgccaac aaagctgccg tcaccaagct tcattaagcc taaaattggg
    28381 accagcagac cacaagccag cagaccgact ccataaatgg agtcactatt ggcacttaac
    28441 gacaagccgc cgatcagcag atagaggatg ccgacaatac caattgccat cgctacaatt
    28501 atgatcgcga cgatcggctg gacgcccagc agctcatcaa tatggaagat cttattgaac
    28561 accagcgatc cagaataaag aaccacgggt aagaaagaag tcatataggt cacaataaat
    28621 aagatcgaaa taattcgttt ggtaaccgta tcataacgaa tctcgatgaa atctgagatt
    28681 gtattgatgc cgtatttaaa atattttggc aagaatatca cagccaaagc tacgatcgca
    28741 atcgtagcag ttacttccca ggccattact tccatccctg catgataact ttgaccattt
    28801 tgtccgacta tttgttcggt ggacaggttc gtcatgatga tcgtgccggc gattggcaaa
    28861 gcagttaagc tccgccctcc catgaagaac ccttctgatc cagaagtatc gacacttctg
    28921 gatctagaat aggcaaataa ccatacacag atgacaatca ctaggaaact gattatagaa
    28981 aaaagattca tcgtctagct ccttttcaat agattaaaga ccggtgacct ctcgaatgta
    29041 gcttctggct ttgactgcat attcaaatgg attggcttta gccgggtcct gttctgcttc
    29101 aactacgatc cagccttcat agtcgctggc atggattgct gtccagattg gagtgaaatc
    29161 aatcatccca tcaccaggaa ccgtgaagac gcctttcttc acgccgttta agaagctgtc
    29221 tttttccttt tctacttctt cagccgtttc ttgacgaata tctttgaaat ggatgtgttt
    29281 gatacgatct tgatgacggt tgtaaaccgc gattggattt tcaccagaaa agaccaaatg
    29341 tcccgtatcg aacaataatt taactttgtc tggatcagtc atttccatta aacgatcgat
    29401 ttcttccgtc gtttgaacgc cggtacccat gtgatgatgg taaacgatct ccatatcctt
    29461 ttcgtgggcc aaatccccta atttttctaa tccttccgcc agttttttcc actcttcatc
    29521 agtgaaaact ggtttatcat caaagactgg cgctgtcata atcccttgga tactatgacc
    29581 ctgctcagct actacgatga ctttagcgcc catcgcatgt aagaaatccc gatgtgcttt
    29641 gaaggcttcg gcagtttctt caaaaggttt agttgtcaga aacgcactga accatgcact
    29701 ggcaaccttt aagccgcgaa tattcaaata ttgttccaac acctctggat cttttggata
    29761 tttgttgcca atctctgttc cggtgaaccc agcaagggcc atttcactga tacattgttc
    29821 aaaggtattt tcactaccaa gctcgggcat atcatcattg gtccacgcga ttggtgcgat
    29881 ggctaattga atttgtttgg tcatattctc acactcctgc ttattttttt agttgtacta
    29941 aactcttcgt atcgaatgat tcttgacaag ccaacgcgat cttagttgat tgcaatccat
    30001 cttctgcatt aaccgctggt tgacgttttt cttgaataca tgagacaaat tcttgggctt
    30061 cacgaatgaa ggcttctctg aatcgttctg ggaagttttg tgaacatgga cggatgatcc
    30121 cttgatcgtt catgatcgtc acaagatttt tctcaggcgc ttgcgctacc cgcagcattc
    30181 ctttggttcc catgatctct gtttcgacat gatagccatg ggctgcgttt ctgccggcaa
    30241 ctagtaaagc tattgtttta tcgctcaggc tcatcattgc ggctccagtt tcaagctcac
    30301 cagcctgatc caattctgga tacgccgcat ttttcccaat cgcccacact tgatcgactt
    30361 cttggccggt aaaccagcga accaaatcaa tatcatggat cgccatatct aagaacaagc
    30421 cgccgctgtc gttattcatg gcaaatttga caaagctttc caagccttcg ctcggatcga
    30481 tcccataaca acgaatcagt gtgatttcgc cgatttcgcc atcttctacc attttcttcg
    30541 catactgata cgactcatca tagcggcgca tgaagcctaa catgaagacc tgttcaggat
    30601 gctcttcgat gactttttgg gtctttttaa tatcttcaac ttcaaggcct aatggttttt
    30661 cagtaaagac atgcttgcca ttttccatcg ccaagcggac ttggtcacag tgaaagcctg
    30721 atggtgaaac aataaagact gcatcgatca cggaactttt gaccatttct tcatagctgg
    30781 aaaaagtatg cttgacgcct aatttcttct gtgcgaatgc taattctgtt tcaactaaac
    30841 tgcacgcagc cgtaagctca caacaactga cacctgttgc taaattttgt gcatgtactt
    30901 ttcctaatct tcctaaaccg acgatgccta ctctaatgtt gttcatgaaa tacctccgtt
    30961 ttctgagaat tactcattgt atagtgctgg tcgttcatcc atttgaatca ttacttttgt
    31021 ttttgtttca cgagactcat gacaagccat catggtgatc gctgctacat acccatccca
    31081 agcggtagga ccgacaaccg catcattttt gatcgaatcg atccacagct tgaattcata
    31141 atcataggca tccaaaaagc gggtctgcca atctggtgaa acaggtgtgt aatttttttc
    31201 ttccgattta attcgtgtat aggctgggtc cgtcattcct acttctgccg tttcgaaaac
    31261 cacatcacat ttaatatcgt agccaaagcg gcaattcaca aagatttcca aatcaatcgt
    31321 tacaccggat tttgtttgaa agatcagcag ctgcggatca tgcaaatcgg catgggagtt
    31381 gctggttttt ttcggcaaga tcatttgaac agattcataa tcttcattta gcaaccagcg
    31441 aagcacatca atctcatgaa tcgcggtgtt gctgatcgcc atcggtgttg tgtagttttc
    31501 atctgcgcta ggatttctat gggcacaatg catcattaat gcttctccgt attgcttcga
    31561 ttcgattgct tctttcagtt caatgtagcc gcggtcatag cggcgcatga agccaacctg
    31621 aaccaatttc ttcccataag caacttccgc atcaacgatc cggcggcagc ctgctgcatc
    31681 catcgctaat ggcttttcgc agaaaacata tttcccatgc ttgattgctt ctaacacata
    31741 ctgctcatgg gtcgggtccc aagaagtcac aacaacgaca tccacatctt cagaagcgat
    31801 caatgcttct ccggtttcaa agaatttagc atcgacacgt ttggcaacct ctttagcagc
    31861 ttttacattg atatctgaga ctgctgtcac ataagcccct tgtgttttct gattgatcct
    31921 gtcgatatgc tcgatgccga ttgcacctgt tccgataacg cctactttta ctctcaatta
    31981 cttatccccc tgttctgttg tttaagcaca catagtatgc gcttacaaaa ttattcctgt
    32041 gtagctttta ttcttaaaag gtagagccct ctctttgctc cgccttttac tacccataag
    32101 cttgtacgta taattcctta atttgactat gactaggcac ctttttatta ttttgcggac
    32161 ttccgctggt caacgcatcc gcggccattt tgtctaaggc tgccataaac gcttgctgat
    32221 caataccata atctcgaatc gttgggatcg acagctgctc acagagctct tggatttttt
    32281 taatcagata atccgcagcc tcttccagcg ataaatcttc ggctgccgga taaataaatc
    32341 tggcgatcgt cgctaactca gtctgaatag catcctttga gaattcaaaa aagaccggca
    32401 ataacatcgc atttgatatc ccatgaggaa tgtgaaaaag tgcccccacc ggtcgactca
    32461 ttccatgaat caatgtgact gacgcattcg aaaaggcaat ccccgcctcc gttgaagcta
    32521 agctcatttg ttctctggct tcagtgtcgt cgctattttc atatgcctga gaaagcgtgt
    32581 tcaaaatttt cttcatcgct tccagtgaaa atagttgcgt tacttcattg gctttgactg
    32641 aaacataaga ttccaaagcg tgacatagcg catcgactcc cgttgccgcg gttacttttg
    32701 gtggtacagt tttcgtaaaa tcagagtcaa cgattgagat ctgtggcatg aaaacgagat
    32761 ccttcatcat cattttgact gctgtttttg tattggtaat aactgccaca tcggttactt
    32821 ccgaaccagt tccagcagtt gttgacactg caatcagcgg aatgcccgct tgcagctgat
    32881 caaaatttct tgcatgaatc gcttcgagac ttaattgatt agcagccaaa acggctacca
    32941 ccttggctgt atccagacag ctgccgccac caaaagcaat gatatgatca cattgatgct
    33001 tctgaaaaag cttcagcgca tcataaacat tttcttgcgt cggttcggct tgaatgtctg
    33061 tatactccgc taattgatca tctgtttttc ccaacagctc cttgatcttt tgaagatgcc
    33121 cggtctgttc cataaccgta tcactaatga ttaacggctt gttgcctagt tgttctgatt
    33181 cttccataag aaattggatt gttccgccgc caattcttaa attggcaggc attttcagtt
    33241 gaatattcac agaaaaaacc tctctctggc ttatagccta taacagaatc ctcgaagctc
    33301 tttaacagag cttcgaagca aatctttaaa tctcactttg cgcataacgt gctgtaacaa
    33361 ctttccgatg ggtataaaac tcaacactgt ctttgccatt ggcatgcaaa tcaccaaaga
    33421 aagagtgctt ccagcctgaa aaggcaaacc aagccatcgg tgcaggcacc ccaagattga
    33481 cccccagcat cccagcatca acattttctc tgaagtagcg aatcgctgat gcgttgttgg
    33541 tatacagaca cgaaccattc gcaaattcag attcattcgt cagctcaacg gctgccatca
    33601 aatcttttac ccgcacgatt gatgcgaccg gggcaaaaat ctcatcctgc cagatcttca
    33661 tatccatcgt gacattatca aaaatcgttg gtccaacaaa atagcctttt tctggaatgt
    33721 tttcgcgacc atctagtacc agtttcgctc cttcatcgac ccctttttgg atatagtcaa
    33781 aggtccgctg ctgtgcatct tttcgaatca ctggtcctaa aaagacccct tcgtccaagc
    33841 cattgccgat cttgatcgct tttgccgcag ccttaaattt ttcaacaaac tgatccgcga
    33901 tttcctcttc caaaacaatg acggaggctg ccatgcagcg ttcaccagca gaaccaaaag
    33961 ctccgccaat aaggtccttg actgcccgat caatattggc atctttcagc acaacaacat
    34021 gatttttcgc tccagtcaac gcttgtaccc gttttagatt ttttgttcct tcacggtaaa
    34081 cgtattcacc gacatttttt gatcctacaa agctgatgcc ttttaccagt ggatcttgca
    34141 gcaatgtgtt gacaacatcg tgggcaccat agacaacatt aaaaacaccg ctaggaaagc
    34201 ctgctttttc aaccagctca acaattttct ccatcaacaa tggtgttttt tctgaaggct
    34261 tcagcaccac cgtatttcct gccgccagag ccatcgggaa gatccagaag ggcaccatca
    34321 ttggaaaatt aaacggtgtg atccctccga ttactccgat tgggtaacga taattcgtga
    34381 tctcaatatc agtcgccgct gttgataaag aatctcccat cattaaattg gtgattcccg
    34441 ctgcgtgctc cacattttcg attcctcgtt gaacttctcc cagtgactcg gacaatgatt
    34501 tcccattttc cagcgtgatc aaacgcgcca attcactttt atgatctgtt aaaagctgat
    34561 gcagcttgaa cagataacgt ccgcgaacag gaacaggaac ttttttccaa gtttgaaacg
    34621 cagcatcggc agctttaact gcttcggctg tctctgcttt gctagacaac ggtacattcg
    34681 ccagcgcttc ttctgtagcc ggattcatta cttcttcaaa ctctgttgag cgactagcga
    34741 cccaacgacc atcaatataa tttcttaaaa atcttgtcat ttat
//
LOCUS       DAIGSZ010000027        34772 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.027, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000027 DAIGSZ010000000
VERSION     DAIGSZ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.027"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(227..1114)
                     /locus_tag="NOB31_001351"
     CDS             complement(227..1114)
                     /locus_tag="NOB31_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0973568.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1111..1980)
                     /locus_tag="NOB31_001352"
     CDS             complement(1111..1980)
                     /locus_tag="NOB31_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0973569.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2117..3403)
                     /locus_tag="NOB31_001353"
     CDS             complement(2117..3403)
                     /locus_tag="NOB31_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0973570.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3676..4254
                     /locus_tag="NOB31_001354"
     CDS             3676..4254
                     /locus_tag="NOB31_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCI0973571.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4254..5183
                     /locus_tag="NOB31_001355"
     CDS             4254..5183
                     /locus_tag="NOB31_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0973572.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5180..6916
                     /locus_tag="NOB31_001356"
     CDS             5180..6916
                     /locus_tag="NOB31_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCI0973573.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="NOB31_001357"
     CDS             complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="NOB31_001357"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HCI0973574.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7812..8321)
                     /locus_tag="NOB31_001358"
     CDS             complement(7812..8321)
                     /locus_tag="NOB31_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HCI0973575.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="NOB31_001359"
     CDS             complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="NOB31_001359"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HCI0973576.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9622..10713)
                     /locus_tag="NOB31_001360"
     CDS             complement(9622..10713)
                     /locus_tag="NOB31_001360"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HCI0973577.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="NOB31_001361"
     CDS             complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="NOB31_001361"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HCI0973578.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="NOB31_001362"
     CDS             complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="NOB31_001362"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HCI0973579.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="NOB31_001363"
     CDS             complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="NOB31_001363"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HCI0973580.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14676..15650)
                     /locus_tag="NOB31_001364"
                     /pseudo
     CDS             complement(14676..15650)
                     /locus_tag="NOB31_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
     gene            complement(15631..17514)
                     /locus_tag="NOB31_001365"
     CDS             complement(15631..17514)
                     /locus_tag="NOB31_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HCI0973581.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17532..19757)
                     /locus_tag="NOB31_001366"
     CDS             complement(17532..19757)
                     /locus_tag="NOB31_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCI0973582.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19872..20906
                     /locus_tag="NOB31_001367"
     CDS             19872..20906
                     /locus_tag="NOB31_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0973583.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20973..21986)
                     /locus_tag="NOB31_001368"
     CDS             complement(20973..21986)
                     /locus_tag="NOB31_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0973584.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22064..22252)
                     /locus_tag="NOB31_001369"
     CDS             complement(22064..22252)
                     /locus_tag="NOB31_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HCI0973585.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(22692..22820)
                     /locus_tag="NOB31_001370"
     CDS             complement(22692..22820)
                     /locus_tag="NOB31_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCI0973586.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="NOB31_001371"
     CDS             complement(22823..24196)
                     /gene="rlmD"
                     /locus_tag="NOB31_001371"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCI0973587.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(24307..25362)
                     /locus_tag="NOB31_001372"
     CDS             complement(24307..25362)
                     /locus_tag="NOB31_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCI0973588.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="NOB31_001373"
     CDS             complement(25372..26802)
                     /gene="gatB"
                     /locus_tag="NOB31_001373"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HCI0973589.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="NOB31_001374"
     CDS             complement(26799..28271)
                     /gene="gatA"
                     /locus_tag="NOB31_001374"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HCI0973590.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="NOB31_001375"
     CDS             complement(28271..28576)
                     /gene="gatC"
                     /locus_tag="NOB31_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HCI0973591.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(28682..30718)
                     /gene="ligA"
                     /locus_tag="NOB31_001376"
     CDS             complement(28682..30718)
                     /gene="ligA"
                     /locus_tag="NOB31_001376"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HCI0973592.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(30735..32969)
                     /gene="pcrA"
                     /locus_tag="NOB31_001377"
     CDS             complement(30735..32969)
                     /gene="pcrA"
                     /locus_tag="NOB31_001377"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HCI0973593.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            33124..34683
                     /locus_tag="NOB31_001378"
     CDS             33124..34683
                     /locus_tag="NOB31_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HCI0973594.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT         9519 a         7494 c         6336 g        11423 t
ORIGIN      
        1 gacaatcagg acagtcatcg gcaatatagc agcaatcact tctttaaaat tttttagcat
       61 gtatcctcct cctttactct ttaagtttac cttaaaatga aagagttttc gagcacaaac
      121 ttaaaacgtt atcatttaat ttttctcaac ataaaataac acacgtccca aaagtatctt
      181 tttacttgga aaaatgactt tgaaggaacg cgcttattgt gtttttttat tttacagagc
      241 cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa tacgatggca gttggtaaag
      301 tagcgatgac taatccagcc atgatcattc catagtctgg tgtataggaa gcacccatag
      361 cagataaaac aagcggaacc gtccgtttat caggagattg caaagctact aagggccata
      421 aataattgtt ccagctactc atgaatgtga tgattgcagc cgcggcatag gtatttttag
      481 ccgtcggcat atacactcta aaaaaaatac ttagttcttt tagaccgtct aatcgagcgg
      541 cttctactag atcttttgga aaagatttaa cattttgtcg aaagaagaag atcaaaaaag
      601 cagtgctaac agatggcagg atgacaacca agaaactgtt gattcccaaa accgttccgt
      661 tcaattgtga aaacattcga tataaaggga tcatcaatgc cgcaaaagga accatcatcg
      721 atagcagtag aatattgaaa attaggtctt ttcgtttact ttgataaatc tcaaatccat
      781 atcctgccat tgacgaaatc agcaatgcaa acacagtggt caccaaagcg atcatcgctg
      841 aattccaaag ggaacgagta aaattcagct cattggaaaa caaattttga aaattgatga
      901 tcaagttact gccaatcttt atttttcccg atgtgatatc cacgggtgta ttcgtcattc
      961 ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga taggatgctt aatgctgtat
     1021 actttaatac tgacccaatt gtcgaacgaa gttctaatgc ttgttttttg acgttggggc
     1081 gttcgattgt ttctttttct accatatttt tcatcgactt tctcctccta ctttcgtttg
     1141 gattatcgac aatatcacaa taaaggaaac aataacaaag gaaactgctg ccgcatatcc
     1201 aaaattaggc gtgaatttat aactcaaatt atagatgtat tgagataggg tggtcgttgc
     1261 atttgctggt cccccgccag taatattttg tacttcatca aaaagctgca atgtcccgat
     1321 cgtcgaagta atggaagtaa acaaaatgat tggttttaaa tttgggatcg tcactttgat
     1381 aaactgctgc catttagaag caccgtcaat agatgctgct tcataaatct ccgaatcaat
     1441 attttgcatg cctgaaagga aaaaaatcat attgtatcca gtccaacgcc aagtgatcga
     1501 aagaatgatc agaactctcg cccaaattgg atgagtcaac cagccaatcg gtgtgtcaat
     1561 cataccaatg cccaacaaca agttgtttac aaggccagat tgagaaaata gacttttcat
     1621 gatcagagaa taactgacca tcgaagtgat acatggaaga aagatagcgg ttcgaaacaa
     1681 ccctttatat ttcaactttt tatcatttaa aaggttggaa ataaaaagtg ctagaaacaa
     1741 catgatcggt acttgtacaa gtaaatacag gaatgtatta aaaaaagctt ttttaaaagt
     1801 tgcatctgtc aacatccgct gataattacc taacccgtta aatgtcatat tgacaggggg
     1861 accactttga aaagacgtga tcaaagccaa aaccatcgga ataaaaacca tgattgatat
     1921 caaaatgact ggcaagatta aaaaagcatg cccgtttttg aataaatctt tctgcttcat
     1981 tcttttccct ccaattctat cattgattat ctacatgaaa agacaagaaa gacaatatct
     2041 gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg atgaaaaagc gaagaaattc
     2101 acttttttac caccgatcaa ttagccaatt gtgcttctac ttgtttttgt gtatctgcta
     2161 gtaccttgtc tgtctcttct ccattgatga ttcgatgaag agcttcagct acgactgctt
     2221 caattgcata ggtctcatgt ccgtaattca cttctggtat ttcagatgtc catgttgaaa
     2281 aatcgtcaaa gatcttttga ccactgtaaa attcagaagc ttcttgataa gcttcttgtt
     2341 cattcgcgct aagcatcgta gatactagtc cgatttcttt cgcaagagtg cccatcagtt
     2401 cttcattcga agcaaacgtt gcttctagga aatctttcgc tgaatcttct ccagctactc
     2461 ctttgatcac ataccagcca gcgccgccaa ggttagaagc ttgcgctttt tgcagatttt
     2521 ctggaagtgc aggtattggt gcaatcttcc attttccaga ttggttttct gctccttgga
     2581 tcgttgaaga ataccaagcg ccagttgggc tagaagctac tgctcctgat tgtatcgcag
     2641 ttactccagc attccagtca gaggtttgtt cgactagatc ttctttcaaa agagtggcaa
     2701 acaattcaag accatacttt aaagatgcat tgtcttggat cgtgactgtc tccccatctt
     2761 cagatgtata ccattctcct gcctgttgca taatcatcct tactcgacca aggtcagaag
     2821 gattgacttc agcgattttc tttcccgtct tttctttgac atctcgcgct acttgaatat
     2881 actcgtccca cttcagattc tccatatcct cttctgtata acctgcttct gccatcagat
     2941 ccgtacgata gaagtttgct gttacgcccg aatcgaaagg aacaccgtat attttatctc
     3001 ctactttgtt taccgcaaat ttatacggtg caaaatgatc ttcctttaca atagcagaca
     3061 aattagcgaa tgcatctgga taagaagtca aatagccttg tatcctataa tcttcaatca
     3121 agacgatatt gggcaatcct tctgtattcc cgctcgctaa agcggtgttc agtttctgaa
     3181 cgatatcatc ctgagacatc gtaacaactt ctatctctgt ttcttcgttc tcataaactt
     3241 tttttgcttc attcactgct ttgatattga atgtctcatc ccacgcccag acagtgactt
     3301 tttcttcttt gtctgctgta ctactagcac ttccgcatcc tgttaagaaa cctgatgctg
     3361 ccgctaaaca aacgactcca gcaattaact ttctgatgtt catttttatc cgctcctttt
     3421 ccatccatta gttgtttacg tttgctacat tcatcatacc aaaatttgaa aacggtttct
     3481 ttattattca gatacttcaa aaatttctcc taaaataata aaaaaataca aatcaactat
     3541 gacaaaagga ataatcttag catctagacc aaagatcgaa atggtgaggt ttctttaaaa
     3601 taaaaatatc cttgcatttt ctcctagaaa taagtatttt taaattacaa gactattctt
     3661 aaggcgggta aaaaaatgcc aatacgcgta attcttatcg atgatgaaca gacgatttta
     3721 gatggaatga aacagttgat caattggtct gagcacgggt ttcaattaat agggactttt
     3781 tccagtccgc tgaaagcgct tgatttttct ttggtacatg caatcgatat cgtggtcaca
     3841 gatgtaatga tgcctgaatt aaatggaatc gaattatcgc ggctattaaa acagcaacaa
     3901 cctgaaacac agatccttat cctctctagc tatgatgaat ttgatatggt taaagattct
     3961 tttaaagaag gcgtcgctga ttatctttta aagcctcgat tgagtcctga tttttttcta
     4021 aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc ccaacaaaag cccaatcacc
     4081 aatcgttatg agcagatctg cgagaatctt tcacagcaga ttgctggaca aactcgtcca
     4141 ttgcttgacc ctcttctttt tgaacacacc ttgtttttct gttatatacc gaaaaacggc
     4201 cattcagttc aaaacaaggc tctaaacaaa aacagtcgat cacccattca ttgatggata
     4261 gcgacgattc gtttactatt tatcctgttt ctaccttttc ggaagaatcc ggctatgtaa
     4321 tcaatactga ttccaaagat acacttagga agtttgttca aaagtttcgt caagaagttt
     4381 ttccaggtga tttttttgtt gtttctgatt cttttgcaat ccaagatatc aatgaaatat
     4441 tccaagagat cagaaattgc accaaaggac aacgtttcta tcataaggga aagaaccttg
     4501 cttatcagca tgaacttctt ccgttattaa ccaaccacga gcagcaagca agtagttatt
     4561 taacaaaaat cgttcataaa gactacgctt tagctgtcaa agaacttgag aatttcttca
     4621 cgacgatatt ggaacagcct attgatccag cttatttgaa acatgaggca atcaatcgtt
     4681 tctatgcatt actcaacgct ttggctgacg agcatgttgg gaatgaagaa ctttctttgc
     4741 tcaagatcgc ccttccttct ttattagccg atgctgagta tttcgaagat ttttctattc
     4801 ttgtcaaaga aacacttgag aaactcaccc acttttctgc aaatgcaaaa aaagacaatt
     4861 tcgatatctt gactttgatc tacgagttcg tccaggaaaa ttatgagaaa gaaatcaatt
     4921 tacaactttt atccgaaaaa tatcattttt catatagcta tctctcagcc atctttactg
     4981 aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt ccgtatcagt aaagccaagc
     5041 tctttttgac ggaaacacgg cttactttga cggaaatctg tgagaaagtc ggctataccg
     5101 aactgggtta tttctccaga gtttttaaag aagagacagg aatgacacct tctcaatacc
     5161 gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag catgaactct ttgccaaact
     5221 tctgttcatt ttgttcatcg gtctttttct gcaagccatc gtcatttctt tgtttattta
     5281 tcatcgatca agggatgcct atatccagct gttcaatcaa tcgaatgatg tggtactaaa
     5341 aaagattcaa tctgaatttg aaagtttgaa tgatacaatc gagaatacat tagccgcttt
     5401 tgattctaat ccagctgtca aaagctattt ttccaatgat ccagcccaac atatggaaca
     5461 gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct ctttcaaaaa tccatccaat
     5521 gatcgattac gatgtattga tctttggaga aaatggaaga acttttgtcg gaaacgacat
     5581 gctcactgcc gtatctgccg attctttttt tcaatctgcg attgctcaga gagtgaatga
     5641 acgtgctgct gatacacaaa tgctttttgc acaccacgga ttgactcttc gcgataagaa
     5701 agcacccagc gtcttctttg tcaaaaaact gaaaaataca ttgaatcacg tttacggata
     5761 tgctgtttta tcgatctcat ccaagcaact agcgaatctt tttcaatctg tagtaaatcc
     5821 tgagatatcg aagatctcct tcatgaacga agaacagacg atcatcgcat caaatgaaga
     5881 aaatacaatt gggagccgat caatgatttt caaaaaacta acagtaggtg aaacaacgat
     5941 ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc caggattgta cattactcag
     6001 tcaagtcgat cttcattctt tatctaacca aatgggcgtg atttttccga ttattttgta
     6061 taatatcgtg acacttgctt ttgctggctc attggtattt atgtatttgg atcgacacac
     6121 aaaatcgatc taccgcttga ttgattcgct aaaacggcta gaggaagatg gcttaaaagc
     6181 tactgttcct gtacaaggaa gccatgaagt ccaattgcta gggaatacga tcaatcaatt
     6241 gctaagtaat gctcagcatc attatgaaca gacgatccaa gacgaaaaga agaaacgttc
     6301 gcttgaaatc caaactatgc aagcacagat acagccccat tttatttata atacgctgac
     6361 tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa gcagttcaag gaatcgacag
     6421 tttcattact ttactaagaa gtacgattgg gaaaaaagaa gaagtgattc cagtcaagga
     6481 agaaatcaaa agcgtacaaa gttacatcga tcttttgagt atgcgatatg gcgaaagaat
     6541 ctcggctaaa ataatgattc ctgatgaact gcagtcatta tctatgccga atatgatcct
     6601 tcaaccaatt atcgaaaacg cctatcttca tgcttttcac aataaaacgc aaggattcat
     6661 cacggtgtac ggcaaaacaa aaaatcagct tcttttattc gaagtgattg ataacggcga
     6721 tggcttcgat actgaaaata ccaaacaaaa aaatgatcat ttttcaggaa tcggcatcag
     6781 ccatgtagat gagcggatac gcctaatgta tggcgatgca tatggcttaa cgatccaatc
     6841 agtgattggg acaggaacga ctgtaacgat ttgtctaccg cttcttccta aaaatcaatc
     6901 agaatatcaa aaataaagaa tagccaagcg ctgatttttt tattttaagt taaataaatc
     6961 aatcagtatt cttgactttc atctacgcgt ctcttctact gtcagcactg gataacagcc
     7021 caatatttga ctttctcctc cgagcatctt gatttcttgg agcgcattct ctactaatgt
     7081 cattggacgg tccaacaaca aatcgatcac gaaaaaatat tctcccaagc tagttttcaa
     7141 tggtcgggat tcaatcttac ttaagttgat ttcccgccag ccaaaagctg ccagcatttt
     7201 atgaagcatc cctggccgat tagcaggtag tgtcaagatg acactcattt ttactggagc
     7261 tgactgctgg ctggtcatct ttcggtcacc gacgatccaa aaacgtgtct ggttcaactc
     7321 attatcttgg atattctcag ctaagatctc caatccaaca tgctgtgctg tttctaatga
     7381 agcaatcgct gctgcgtctt ctttcggatg ttctgctaca tacattgctg cagcagttgt
     7441 tgattctgtt gctactaaag gaacattagg ataatgcgtt tctaaaaact gttgtgattg
     7501 tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt gttgctggat tgcctaaaag
     7561 ctgctgcttg ataggaagaa cgatttcact tttaacttcg acttctggat gtttggaaag
     7621 aagatcgatt gtgtgatgaa cagctccttc caatgaattc tctacaggaa cgacagccag
     7681 atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg atggaagcat acgcagtcaa
     7741 ttgttctgta ggaaatagct gacaagccgc ctgataagtg aatgaacttt ctggccctag
     7801 atagctgacg ttcatatgct tttgatcctt tctataatgg tatcgatgat cttttctggt
     7861 gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt cataccaaga aagtcgttgt
     7921 gccaataatg cttttatttc ttctcttgtt tttccaagag ctaaaggtcg aatagacgtt
     7981 tcatcttgtt ggatacgatc aactagacag tccgcttctg cctctaagta aagaacaatc
     8041 ggctgtgttt ttaaaaaacg ccgattttct gcactttgga caatccctcc accagtcgcg
     8101 ataattttgt cttcatttga cagctttctt aaaatatctg actccacttt tcgaaagctt
     8161 ttttcaccgt aatagtgaaa atattcggca atcgacaatt ggatatgttc ctcaatcttt
     8221 gtatctaaat ctacatactc tttttgtaaa cattgagcta accctttacc gattgttgtt
     8281 tttccagcgc ccatgaaacc aatcagcaaa atgctagcca tgagcttctc ctcctgacac
     8341 aagttctgct aaatcgtcaa aaaatgccgg ataagagatt gaaacagctt cagctccttc
     8401 tagttcgcaa ggtccatcag ctatcaaagc agctacttgc agcatcatac cgattcgatg
     8461 atcgcctctg ctggacactt ttgcgccatg cagaggtgtc ggcccatgga tgatcagacc
     8521 gtctgctgtc gcttttatct ttgctcccat tttctgtaat tcttctgcca ccgcatcaat
     8581 tctgttggtt tcttttactt ttaattcttc tgcgtctttg atgatcgtga ttccttctgc
     8641 ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc agacgcggaa tgatttctcc
     8701 accaatcgtt gctttcttca aatgactcgt cttgacactt aaatcagccg attggttctg
     8761 ttcattgtga ttcgtctggg taatcgctgc gcccatctcc tccaacacat ctaagatacc
     8821 agttcttgtt ggattgaccc cgacattttt taacaacagt tggctttccg gaacaagaag
     8881 tcctgctgct agaaagaaag cagctgatga aatatcacct ggaacagtta tctgttgacc
     8941 agttaatttt tgcggtccgg tcactatgat cgttttatct tccactgtga tccttccgcc
     9001 aaattgacga atcatttctt ccgtatggtt acgggaacgt tctttttcaa cgattacgga
     9061 tgtgccttct gcttgtaatg ccgcaaacag caaagcagat ttgacttgcg cactggctac
     9121 aggcatattg tatcggatag gtgataaaga gcgggttcct gtcacagtga ttggtagata
     9181 ctggtcattt tcttctcctt gcaagtcagc gcccatctcg cgtaaaggtt ccatcactcg
     9241 ccccattgga cgtttagaca acgaagcatc cccgaacaga gtagtcgtaa aaggctgtcc
     9301 agccaaaata cccatcaata aacgtatggt cgtaccggag tttcccatgt caattgattc
     9361 ggttggttgg acaaatgagt ggctaccgcg accatgaatc ttgatcacct cttcctcttc
     9421 ttcgatctcg acacctaatt gttggaaggc atgtaaagta ctcagacaat cttctgcgcg
     9481 caaaaaattt tgtatagtcg tcgttccttc agcaattgct ccaaacatga tgctgcgatg
     9541 ggaaattgat ttatctgctg gtatcctaac agtccctctt aatccatgta tttgttgtaa
     9601 taattgcatt tatccagcct cctatttgat ccagcaatga taactggtat tagacataat
     9661 gattcttttt gcttgtaaca aatcctgttg gtttttaaaa ctgatttgca gtattcctaa
     9721 aatatcttcc ctggtctctt ggatcttcaa attaatcaaa gaaactcccg cttttccgat
     9781 cagtccagtt acttctgcaa taacgccagg ttcatctggc acatcgataa ataaatcaaa
     9841 aaaggcagga atcgcgcctt gcttatggac aggcaactgg tctcgacttt cttttgcccg
     9901 attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg atccattctg ctatttgtgt
     9961 catttcttgt tgccaatctg ccaatcgttc caataatatc tgcttattgc tcaacaaaat
    10021 atctgtccac atgacaggat ctgaggaagc gatcctagtg atatctcgaa agcctcctgc
    10081 tgccagttgt ttggctcgcg gatactcttg attgaattgt tctgcctgat tgactaagcc
    10141 agctgccaga atatgtggaa aatgacttag cattcctgtt atacggtcat gttctcttgc
    10201 tgtaagagtt acatattttg ctttggttcc gcaaaatagt tcttgcagtt tttcaacatc
    10261 ttttttcgtc ttttccaaag gtgtaaagat gtaataggca ttttcaaata gtttagcatc
    10321 tgctgcctgt atacctgatt tatgagaacc agccattgga tgtccaccga caaaccgaag
    10381 atttttctgc tcagcggatg tcacgacttg ctgcttcgta ctgctgacat ccgtaatgat
    10441 gacgtgatca gacaagttga ttctttcaag gacatcaaga taagctaagg ttgtacggac
    10501 gggaacggct aataagataa cgtctgcttg ttctgcacct gtttcaaaat cacttgcaac
    10561 gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt tttgactgac tatcccaacc
    10621 aactactatc agttctggat tggtctgacg aatacaaagt gccatagaag caccaatcag
    10681 tccaagcccc acgataaaaa catgttgtgc catcttattt gccccctttt tagtaatgtt
    10741 tcaagtagtc acggtactcc ttcactgcag ctttcaactc aacaagcgaa tcacttggga
    10801 attttgacaa tagctctgtc gctaccacag tggctacaac attttccgca acgacgctag
    10861 ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc tttgtaaggt tcttttgtat
    10921 cgatatcaac actttgaagt ggcttgtaca atgtaggaat gggtttcatg accccgcgaa
    10981 tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc gcctagatta ttggtacgtc
    11041 ggaaatagcc tctttcttct tcccatagga tctcatccat cacttctgag cctggtaatg
    11101 aaccagaagt gaatccgacc ccaaattcta cgcctttaaa ggcattgata ctaaccacag
    11161 cttgtgcgat tttggcatct agcttcgtgt cccattgtac gtagcttcct aatccagctg
    11221 gaacgcctcc aacgagcact tctacaattc ctccgatcgt atctccattt ttctttgtct
    11281 gatcgatcaa atcttttatt ctttgctcaa ctgctggatc aacaactcgt acttctgacg
    11341 cttcagaaat ttctttgatt tcttgaatcg agatatttcc aggtatttct gcttggattc
    11401 caccaagaca aatcacgtgt cctgctacga tgatgtcaag ttcttccaga attttcttgg
    11461 caattgcgcc gattgctaca cgcatggtcg tctctcttgc agaggaccgt tcaagcacat
    11521 tccgaagatc tcgatgatgg tatttcatac cgcctaccaa atccgcgtgt cctggacgcg
    11581 gacgtgcaac tcgccgcagt gattggtctt tttcaggcac ttctgctaca gacatgacag
    11641 ttgtccaatt tttccaatct ttattttcta ccactaaagt gacaggtgaa ccaattgttt
    11701 tgccgtgacg gatgccagac gtgatccgaa cacgatcttt ttcgatcttc atccttcctc
    11761 ctctgccgta accagcttgt ctgcgagcga gttcgtgatt gatttcttct tctgacagag
    11821 gtaatcctgc tggtagtcct tcaataatgg ctgttaattc tggtccatgg gattctcccg
    11881 cagtcatata acgcatctta cagtcctcct aagtaatctt tgaatgtctc tgtgggaaca
    11941 ggaacgattt ttgcttgccc aatcttttct agcaagatga tattcaattg gcttcctctt
    12001 gctttcttat catgggttat cgcgtggaat aattcatctg gatgacttag atcgtacgta
    12061 atcggcagat ggaatttttg aagtatcctt tctaaagcag ctgtcgatcc agttggagac
    12121 aagccgattt tttctgcatg agaagtgatg gctaccattc caatagctac tccttctcca
    12181 tgactgacta ccccatatcc tgctgtattt tcaattgcat ggccaattgt atgaccaaaa
    12241 tttaaaataa gtcgatttcc ttggtcaaag acatcttctt ccactacttt tcgtttgatt
    12301 tccaacgtag cagtaatgat tggaacagca tgttccagaa gatctttttc gtctttcagc
    12361 tcgttcagct gtttccaaag cgttgcatct gctatagctg ctgatttgat gatttcagcg
    12421 attccttctc gtaaacgacg taccggcaaa gtttttagaa cctcaggatc aatcaataca
    12481 ccagctggct ggctaaatgt tccgacaagg tttttcgctt tgtttgtatt gactgctgtc
    12541 ttcccgccaa tactagaatc tacttgtgca agtagcgtag tcggaatttg aacgaaatgg
    12601 atcccacgca tgaacgtcga ggccacgaat gctgctagat cacccaccat tcctccacca
    12661 agtgcaagta tcccatcgct gcgggtaaaa tcattatctg ctaaaaaatc gtataactca
    12721 gctgcttgtt ctaaagattt actggtctca cccgccggta cgattgaaag gactggttca
    12781 aaattagctt gtctcaattg gaacatgatt ttttctgcat atagtggagc aacgtttgta
    12841 tcagtgatca cagctacttt ttgaggtctc caaatcgttt gaagccatga tccagcctgt
    12901 tctagtgcgc ctttttcaat atgaatatcg tatttttggt tatcaacatg tacagtaagc
    12961 attcgtttca cttctttctt ttaaaaagct ggaattaatc gagtgtctga atcttttcca
    13021 ttgcttcttt catgatcgca acttctttca tcatgcgtga gtaagtcttt tcattcaacg
    13081 attggggacc gtctgaccaa gcatttgcag gatcaggatg gatctctacg atcatgccat
    13141 ctgctccgct tgccacaccc gcacgagcca ttggtggtac aagttcccaa attcctgtac
    13201 catgacttgg atcaacaatc acagggaaat gagttaattt tttcatcaat gggacagcac
    13261 ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg aatcccacgt tcgataaaaa
    13321 tgacaggaga tttgtcttcg actgcaatgt attctgcagc attaagccat tcattgatcg
    13381 taccggaaat tccacgtttc aatccaacag gtttacctgt tttaccgaca gcagatagca
    13441 gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat atcgctgtac tcagccacca
    13501 tatcgatatg cccttcatcc atcacttcag taatcacttt cattccaaat tcatcagccg
    13561 cttgacggat gtatttcaat ccttcttctt ctaaaccttg gaaagcatat ggagaagtac
    13621 gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc ggctttggcc attcgcgcac
    13681 attctctgat ttggtctaat ccttcgatag aacaaggacc agccatcgtc acgaaactgc
    13741 cgtcaccaat ttttactccg tctacatcca cgactgtatt gccaggatgg aattctcgag
    13801 aagtcaattt gtatgtgttt aaaatacgca cagcattttc tactccttca tagcgtgtaa
    13861 atgctccttc ttgtaaactt cgcgtatcac cttttagtcc aatcactact cgttctgttc
    13921 cttgatcgat tgagactttg aatccttctt tttcgatatg atcgacgact ttttttattt
    13981 gttcttccgt tgcttctttt ttcataatta ctatcattgt ttttcccgct ttcttttgtt
    14041 tacttatcta tcttggctga ttttctctac tttttcaagg tggttttaca ttaattccta
    14101 ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc tttcctactt atgacccaga
    14161 taatcaacaa aaaaagatgt ccctgtagga aattgcctct acagtgaaca tcttcaacga
    14221 gccttaaaaa gcgctgcaaa aatataaaat agccactata gatgaatttc tctacgtggc
    14281 tgtaagtcgt gtttaaaaat ctttagccat catagataca aacctggttt gtttgtaccc
    14341 acgaagtcat gaatacaaac ctatctaaaa tagctaaagt aatacgtatt cagttttgta
    14401 agttttctag atttcataaa aaatcgctcc aaactgatgt aagaattgta cctagtatag
    14461 acataaaaaa atcgactgtc aatcattttt atgaaacttt ttttaatttt ctgatagtta
    14521 actttgtttt tcagaaaaat aacaattggt tttattgaag aaaatagtca tgaacaaaag
    14581 tatctgagaa cttttttact ctcttgttca tgacatatag aataaagcag ctttgtcttg
    14641 taaactccgt ttttcaaata ataatctaaa gattgctact gaataataaa gccgatttca
    14701 tggtcctctt cgctgctgat tcggtaaggt gactcaacat ccgctcccca gctattgata
    14761 cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg ttcgtctttc tggcggtagt
    14821 tcttctatat gtgttgcctg ttccagttct tctgctttga atggtaaagc ggaaaaagca
    14881 aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt cttgatcttt atccgtatta
    14941 tccaacgttt gatttcttgt tagttctacc catttcgttt ccatatgcat gccgcattct
    15001 tggggaacaa ggtatgggga aacggggagt cctgccactt tataaatacc ttcgacacca
    15061 ccagccatcc gatccggata tgtttcccct gataggcctt catactcaaa aaattttgct
    15121 ttcgttggca taatgaacct taaacccaat gcgggtaatt ccggtaatca tttttgtcca
    15181 taataatgca tattgacaag cattttaccc tctccagcga tttggtagga aattgtcact
    15241 tgggtttttg gtactgtgtt gatttccagt gtaaaaatga tttcaaccgt ttcagcgtat
    15301 tcattacttg aatattgatt atttactgga gcaatcggca aatcgatctt tttattgtcc
    15361 accagtactt ctatttcttt gacttttgga tacaatccgg ctcctaacca cataccggat
    15421 ttaaatccaa atccgctacc tctgtcatta tcggtcgttg ctcgccaaaa aactggaagt
    15481 gtttcccggt atagccattc ttttccgttt ttattgagcg attccagtcc gcctcttgta
    15541 taagaaaaaa tataatgcgt attccccgat ttgacaccta atgtacagtc gccgaagacg
    15601 attgcaactt tttccgtatc catatgactt ttatttactg tatttttcat aataatatct
    15661 tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa acgatcccat tccctgagaa
    15721 ttcatagtca cttggtttat cgtcaaagtc accgccatag cgcatcactt ctctgcctgt
    15781 gattggatca gtcacttgga tcgcctgatc tttaaaatcc catatatagc ctccttggta
    15841 catttcataa cgatcaagca acgtcatgta agaatccatt ccacctaacg aattccccat
    15901 gtcatgcata tattcacata agatgaacgg tttttccgct ttattttcaa ggtagtcaat
    15961 gatctcttct ggtggcgcat acatgcagct ttttacatct gaaatcgaat cttcgaatgc
    16021 tggatttgga aaattccctt cataatggac aagtcgatcg gggtctactt ttttgaagta
    16081 atcgttcatt tgtcgaatgt tttcttccgc ataagattca tttccaagag accaaaaaag
    16141 aatacttgga tggtttttta atgtttcgaa attcgttttt gctcgatcaa gaacagccgc
    16201 ctgccactga ggtactgcac ctggtacgtt gtaagaaggc tcaaatgcgc ccattttttg
    16261 ccatgagcca tgggattcga ggttcgtttc cgccatcaca tggattcctg cttggtcgca
    16321 taaataatac caagtgatct ggttggggta atgagatgtc cgtacgccgt tgatctttgc
    16381 attttttatg atagccaaat ctttttccat atcttctata gtgatggcgc gtcctttttt
    16441 cggatgccac tcatgtcgat ttaccccgtt gataatcatc cgttttccat tgaagtagat
    16501 gattttatct ttgatttcga ttttacgaaa accgaaggaa tagtcaatat actccgttac
    16561 tcttttttct tcgtctatcg tctccaattc aagcttatat aaattgggct gaaaatgccc
    16621 ccacagtgcc acattttcaa atccatcgat gcgaatcgtc atttgctctt ttaacggata
    16681 ttgctgttga tagatttcct tcccatcagg atctagtatc gctacattca gctgactgtt
    16741 tttggctact tgctcaaaag acaaatctac ttcaagtttg ccattttgac atttgtcatc
    16801 taagcgaggt ttgatccaaa gatcttctaa atggttttgt cctcgagcaa ctaagaagac
    16861 atctctgaag atcccaaaaa atcggaaaaa gtcctgatct tccaagaatg cagctgtact
    16921 tcttttgtaa acctccacag ctagaatatt ttcttcttcc aaataaggtg ttaaatcaaa
    16981 ttcagacgga gtgaacgaat cttcggcata cccgataaaa tgaccattca accaaataaa
    17041 cattgcttgt tctacaccag caaaatgaat cgagatttgt tttcccttta gaccttcttc
    17101 taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct ttagcagctg aaaagatccc
    17161 ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg cgaaatacat gtccctccca
    17221 cggatacatc gtattgatgt aatggatctt gtcataattt gctaattcaa tatgactagg
    17281 aacagtgatt tcatcaaaag aacaggcatc aaaatctttt ttataaaatg tttttggtcg
    17341 taccgaagga tttggcgaat aacaaaaacg ccatgatcca tttaaagact gtttaaggga
    17401 ggatgtggtt tctacttctt cccttgttgc ataacaaaca tgatcgctat gtgcatttga
    17461 ttggttcact ctaaaaactt gtggatcatc taaccatttt atatttgctt tcatactttt
    17521 ttccttctct ctcataactt tttgaaatga agcagttctg tttggaaatc accttgaaaa
    17581 tcggggaagt aaagtccaac tgtcatcaat tcggcccccg aaaatatccg cttcgaggtc
    17641 tgttcctgat aaagtgcctc atcatctaac cccatcagat atacttcatg gaacgctggt
    17701 tgagctgaag ctagtatcct ccctaaaaac acaatagctt catcttgttt aggagacaca
    17761 aacatccatg cggcaatatt ttcttcaaaa ggactcgcca aacgataata atggccatac
    17821 tggatcaccg gacgaatcgt ttgataggat ataatttggt cttttacttg ctttttttct
    17881 tcaggagaca gctttgtcaa atccagttca taaccaaaaa cagcgctcat agctgtttct
    17941 cctcttgttt tcaacgaagt agatctgtcg gtctgatgat ttggtacagc tgatacatga
    18001 gctgtgatgg acgaaatcgg ataagcaagg cttgttccat attggatttt catacgctcc
    18061 actgcatccg tgttatcact tgtccatgac tgcggcatat aataaataaa cccggcatca
    18121 aaccgtccac ctccaccaga acagccttcc cataagattt ccggataatc agttgtcaaa
    18181 tgttcaagta gttcataaag cccgagcata taacgatgcg ctacttctcc ttgtctctgt
    18241 gggtcaaggg taatcgaata gacatctgaa agcgaacggt tcatatccca tttgatgtag
    18301 tcaagaggaa tcgtatctaa aatctttctc atttgtttct caatcgtctg ccgaacatct
    18361 aaccttgtaa aatccagtac atgttgtgat ctggaagcag aaggcattct acctggctcc
    18421 tgcataagaa aatcaggatg tgttcgatac agttcagaat caaccgagat catttcaggt
    18481 tcaaaccata aaccaaattt caatcctttg ctatgagcat aatctgctat ttcacgtaat
    18541 ccatttgtca acttgccttc atactcgaac cagtctccta atgaagaatt gtccgcatct
    18601 ctttttccaa accagccatc atctaatacg aacatttcga tgcctagctc ctttgcttca
    18661 tcaatgatcg ccttgatttt ttcactattg aagtcaaagt aagtggcttc ccagttattg
    18721 accagaatcg gccgttcagc aaattgatga cgacctcttg cgattctttc acgtagcaac
    18781 tcatggtgga tctgactcat tttgttcaat ccctgacttg agtaagaaag gatcatttca
    18841 ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa aacgatggct gttgatccca
    18901 ccgacgactc tcaattgatt gatctgatct ttttcaagtt cgaaagaatg gttgccggaa
    18961 taaacaaatt gaagtccgat cgcttctcca gtattttctg tcgtatgatg atgaactaaa
    19021 gcaataaagt tattcatatg gtgactgctc gttcctcgac ggctttcaaa tacttttgtt
    19081 ccagataaaa cagattgccg tgaaatctgt ctttcattga catgtgctcc tggcaaagca
    19141 atgacttcat caaatcgcct agtatgggca aagtctagct ggaaactagc cgctttttct
    19201 agtttgattg tttctccggt ttcatttctt atctttacag atcgtgtgat cactgctcta
    19261 tcagtaaata tggtatagaa caaatcgaaa taaatcgctg tttctctatc cttaagtgaa
    19321 atcaccaacg tttgtgcctc tgacttgtcc atcacataag tttgaggcaa gccttcgatc
    19381 tctggcttcc catctgtaat ataatggctg tcatatctca gatccagtaa gtctgatcca
    19441 ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca tgctgccatg agaagagtat
    19501 tcttgcggta gtgtatcttt cgacagagac cggtcaggat ttaagggaac atttcctgaa
    19561 aatccacgat ctcttcgggg ataattttta ttgtctttgt actgcttgac tggtttgcca
    19621 aaataaatat gcgccaatac attgctttct tctatcttta tcagataaga aagaaatgta
    19681 tttcgtaaat ggaagactcg gctcttttca tcaaataaga tgaaattttt atctgttttt
    19741 ctatgcgtaa tatccatcat ttcactccca acaaaacgga aaccgtttac ttttttttat
    19801 aattcctgta tactgtttac taaacaattt tgtcaataaa aattttttat ttttttgagg
    19861 agtgtgtaaa aatggttgga attagagatg tcgcacgaaa ggcaaatgtc tctcctgcta
    19921 cagtttcccg tgtgttgaat aacgatcaga cgatccatgt ggctcagact actcggcaac
    19981 ggatagtaga ggcagctgct gcgttggatt atgacatcag tactcgtaaa tatatcaaaa
    20041 agagaatgcc ttcgattggt gtgatctcta cgatcggcaa agcgagcgaa gaacaggata
    20101 tctattacaa acatttgcga gtagggatgg aagaagaagc tcgacgtctg catttaggga
    20161 tgaatcgaat ctataatcta tctgataatc ctaaacaatg ggaagatcta gatcagttag
    20221 gtgcggtgat cgttgttggg actgttacga aagaatcgat taccgccttg ttaaaacaaa
    20281 acatgcaaat agtcgtcgtg gataaccctg acatccagca agaggtcgat atggtgtatg
    20341 cagatcttga acggatgact aaaaccgtac tggaattgtt cttagaaaat ggtcataaaa
    20401 gaatagccta tatcggggga tataaagtcg atatggatga attcggtggg aagcagattt
    20461 ctataaatga aaagaggatg cgtgcctatc agcattttat gatcgatcat cacttagaaa
    20521 aatatatgtc ttatcatcta ggtggctgga cagaaaaaca aggtgaggta cttgcgacta
    20581 atctattaga aaatgaatcc cctcttccta ctgccattct tgtcgggagc gatccaatgg
    20641 caattggtgt ctatcgggca ttgaaacaaa aaaatatcca aattggagaa gagattgttg
    20701 tagcaagctt tgataatatc gagacaatcg caaacctctc ccctggcttg accagtgttc
    20761 aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat ggcattggag cgaattgacg
    20821 gtatacggga cgaaccaatc attttgactt atcctgcacg attgattgtt agggaaagtt
    20881 ttatcccaag aacaaaaagg tattgaaaga gaggttgtga aaagccgctt cgtttcttca
    20941 tactcaaaac gaaacggctt tttcacaacc tcttacttat acttattcac aaaatccaat
    21001 gtctgctggt aacaattttg cgattctttt agcgtgtaat caaattggta ttcatgggta
    21061 atctcttttt ttgtatctgt ataaaacaag gattgcacgg gtacctttaa ttctgtcaac
    21121 cgattttcta atgcttgacc ttgctcctgg aatgagtatg catttccgtc agttatatac
    21181 gttggcggaa attccttaga aacatggtca gccacactag cttctttcaa ttgctcactc
    21241 gttttccaat cttttgttcc aatcaacgac cacgcaacgg ttttgacgaa aaacttcata
    21301 aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat caacaggtcc gcaataagaa
    21361 atggttcctt tcagactatc ttttggaagt agctgtttga ttttcatttg tttagcatac
    21421 gcatcattcg tttgtatagc tgcatattgc aatgcgattt gtgaacctgc actatctcca
    21481 ccaaaaaata attgttccat gtctagcaat ttgtcgtctt tttcttcagc taataaatct
    21541 ttgatcagtt cattcacttg aagaacttga ttagggtatt ctgaatcagg cgctaattca
    21601 taattcatcg caaccactgc gatgttggcg tctgaaacta attttgtcgc aaattctttg
    21661 acacccgatt tatctccgcc gacgaatcct ccaccatgta cccaaaatag aacaggaaca
    21721 ggccccttgc tgttttttgg atagtagatg tcataagtat tctctttata cttggactca
    21781 tacgtcaaat ctgttttttt cgccacgttt ttttctgctt gatcgaacgt ttttttatca
    21841 gtgatttgaa cagtatttga aaacatatgg ttgatcaaga atgctccagg tctgggggaa
    21901 agctggaagg caagaaagat tgcaaacgcg atcccaagaa tgattccgaa gaaccatccg
    21961 ataaatttaa gaattttctt tttcataagg ctccctcagt agttagtatt aagcattctg
    22021 attataccat agtgttattt cctatcaagc tctcctagat gatttaatga ttttccccaa
    22081 acttcttctg caatgctttt gacaaaagaa attttttcca ttgttcttca aacaaaacat
    22141 tttcttcttc tgttgaagca aatccacatt gaggacttaa gcacaaacga tccaaaggca
    22201 gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg gtgctcttcc atttcgccat
    22261 ttttcgttac agtcaaaatc taagacaact aatttatctt cagagacttt ctctaaaaga
    22321 acaaaactcc cagcacgttc actatcgtat tctaaataat aggcacggac attttcttga
    22381 gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg ccgccaaaat cgaataataa
    22441 tttccgcgtc aaacatgtat atttagtgtt gaatcatttg agaatatgaa aataaaaatc
    22501 tttttgatca atcagttaat caaattgaaa taacgaaaaa tctgagacag aatgacgttc
    22561 attctgaccc agatttgatt ttgcacaact caacagtcct tattggcaaa tcgccaaaat
    22621 aatgtagact aactaaaaag actaagaaac aataacaaaa gttaacactt cttagtcttt
    22681 ctttagcacg tctatttatt aaagatttta gggccttttc tcatgttttt acgatcattc
    22741 ttaggtgttt ccatttgttt ggatcggcct ccaccttgtt tctttttgat caattctttc
    22801 attttttctt tttggtccat ttttattctc ctttaacgaa tgaagcgact aattcgatat
    22861 gatgggtttg cgggaaaaga tctacaggct gaactttctt cacggcataa cctgcttctg
    22921 caaataactt agcatctctt gcaaaagttg ccggattaca tgagatatag acgattcgtt
    22981 ctggtgacat ttcgattgct gattcaataa aatgatgatc taatcctttt cgtggagggt
    23041 caactacgat cacagatggt ttgatccctt tttcttgcca ttttttcata actttttctg
    23101 cttttccgac ttcataatga acattttcga ttttattatt taaagcattg aactgtgcat
    23161 cttcaattgc ttctggaata acttccatcc catacacctt atccactctg tctgctaaag
    23221 acaagccaat cgtacctatt cctgaataag cgtcgatcac aatgtctttt ttatctaact
    23281 cggcaaactc gatggctgtt tggtacagat actctgcttg ttgagtattt acttgataaa
    23341 atgactttgc tgagattcga taggtttttc ctaatagctg atcttcgata tagtctctgc
    23401 catataaaac tttttctttg tctcctaaaa tcacatttgt tttttcttca ttgatatttt
    23461 ggatgaccga aaccacttct ggcaattctt catgaatagc ttcagcaatt tccttggatt
    23521 taaagaattt ttctttacga gtaactaaaa cgaccatcat ttcatgggaa taatgaccac
    23581 gacggataat gatgtgacga agctgtcctt catttttttc ttcattatat cctcgtactt
    23641 ggaaccgttg caagatatct ctgactactt tgattgcttg atcgatgaca ggatcttgga
    23701 tataaaaatc ttcgataggg actagatcat ggctattctt tttgtaaaaa ccggtggcta
    23761 actgtccatc gatacggcga acagggatct gtgctttatt acggtagccg aatggttctg
    23821 ccattccgac cgttggaagt acaggaactt ctggcatctt agcaatcttc gccattacat
    23881 gctctacttg tttttgtttg aagacaagct gttgttcata cttcaaatgg gctaaaggtg
    23941 cgatacctat gcgaagtaat gcattgtttt ctacaggctg acgatcaggt gattgtgtaa
    24001 taaatgtttc gacttttcca tatccaaact tattgcctgc ttttactact agtatttcta
    24061 cttcttctcc agggagtgca ttttcgataa ataatggata accatcgatt tttgctaccc
    24121 ccattccttc ataactcaag tcgacgattt cgactgtata tcgttcgttt ttctttacta
    24181 tttgctgttc tgtcatattt tgctccttta agcctatttt tcaatcctac tgaactctac
    24241 tataaatcag ctaattacac aactaaaacc ggcactgacc ttactacgtt cagcaccggc
    24301 ttttgattaa ttcttttgat taggtgtttc gtctgctatt tttccgtcac cgtcgatatc
    24361 ttcatccgtt aaacgttcga cttcttttac gaattctttg ctgacaacct ctaattcttc
    24421 ttcatctgta cctgtgattg cttcatcagg aatctgatcg gtattggcaa agaactcaat
    24481 gtgttgatga agattttgga aatgcatcgg tgcttccccg ccgtattcac catctaagtt
    24541 gatcattact ggtcgattga tatcatcttc tgtttcaacg aacaaactgc ttgttttggt
    24601 atagattatt cttggatcat cgacatgtcg accgccattc agcatgagtg ctgcaatatg
    24661 caagatctca aagatatttg ctgtcttcac aatgattaaa gaaaacttcc catcatccaa
    24721 tttggcatct ggcgcgatct gttcgaatcc tccaacagag ttcgtcagcc ctaggaaaaa
    24781 catcgaagca tttccgatat attccccttc atcatacttc aagcgcattt tgattggctt
    24841 tactcgaggg agcatctctg ctcctttcgc aagataagca agataaccaa aaatactctt
    24901 tagttctgat ggaacttcat aagtcaattc tgtcaaatag ccacctgcag cgatattgat
    24961 gaagtaactg ttatcagaaa ggccgatgtc catttttacg gtttggtgtt tttttatcac
    25021 ttctgctgct gctttaatat tatctctagg aatttttaat gctcgagcat agtcgttcgt
    25081 tgtaccagct gggatgatgg ccattttagg acggtgttca agcggagcga ttccattaac
    25141 cacttcgttg attgtgccat cgccaccagc tgccactact agatcaaaac ctagttctgc
    25201 gactctacat gcttcattct tggctgaatc tggttctggt gtagttgcat aggcgctggc
    25261 ttcaaatcct gcttcttcta atgcctgtag gatatccgcc aaattttttt tcaataattc
    25321 ttttcccgag gtggggttat aaattacgcg tgcttttttc attttcagcc tctatcgttt
    25381 cgctaattca tctttaagta gcttattcac gacaccagga tttgcttgtc ctttagttgc
    25441 tttcatgatt tgaccgacta ggaagccaac cgcacgatct tttccatttt tgaaatcatc
    25501 gacagattgt tggttgttat ccaaaatttc attaatgatt ggcagtagtt tgttcggatc
    25561 agataattgc acccaaccat ttttttcaac tacttcttgg gcttctccgc catttgtgat
    25621 caattcacgg aagacttttt tggcgatttt tgagctgatc gttccatcgg cgatcaaacg
    25681 aatcattcct gctaagttct caggtgtcaa ttttgtctca gctaattcca gtttctcact
    25741 gttcaagtaa gcagaaactt cacccatcaa ccagttagat gcttgcttgg catctgcacc
    25801 attttccaaa acagcttcaa aaaaatcaga catttctttt gtaagtgtca ataccattgc
    25861 gtcatactct ggaagtccaa actcacggat atagcgttcg cgacgagaag ctggcatctc
    25921 aggcaaacta gcttttactt tttgaatcca ttcgtcatcg atcacgaatt tcgggatatc
    25981 aggctctggg aagtaacgat aatcactaga cccttctttg acacgcatca aaactgtttt
    26041 attcgttgtt tcgtcaaaac ggcgtgtttc ttgttggatt tctcctcctg aaagaagaac
    26101 ttttgcttga cgtttttctt caaaagctaa accttttttc acgaaagata aagagttcaa
    26161 gtttttcaat tctgctttcg taccgaactc ttcttgtcca taagggcgaa gagaaatatt
    26221 ggcatcacag cgcatagagc cttcttccat tttcacatcg ctgacttctg taaattggat
    26281 aattgatcgc aatgcttcta gataagcgta tgcttcttct ggtgaacgca tatcagcttc
    26341 agaaacgatt tcgatcaaag gcgtgccttg tcggttcaaa tcaacgtaag aataaccgcc
    26401 aataccatgc atgttttttc cagcatcttc ttctaaatgg acacgttcga tccggatttt
    26461 tttcttttta ccttctactt cgatttcgat ccatccgtca tgaccgattg gttgatcaaa
    26521 ttgggaaatt tgatatgctt ttggattatc tgggtaaaag taatttttcc ggtcaaaatg
    26581 agtatcttta gagatttcac agtttaatgc caaagctgct ttcatcccga attccagcgc
    26641 agctttattc attactggca gcacgcctgg ataaccccag tcgatcacgt ttgtattgct
    26701 gtttggttct gcaccaaaat gagctggcgc tggagagaaa atttttgagt tggtttttaa
    26761 ctcgacgtgg acttctagtc caatgactgt ttcaaaattc attcgtcttt ccctcctaaa
    26821 atagctggtt gttgtttatg gaattctgtt gcttgttcaa acgcatatgc cgcttgatac
    26881 atcgtttttt catcaaaata attaccgatg atctgcaatc caactggtaa tccttctgat
    26941 aaacctgccg gtacagacat acctggaagt ccagccaagt tgacagggat cgttaagatg
    27001 tcactcatgt acattgtgat tggatcgtta atgttctcac cgattccgaa tgcaactgtt
    27061 ggtgaagatg gcccgatgat caagtcataa tctgcaaaga ctttttcaaa atctcgtttg
    27121 atcaatgtac ggacttgtcc tgcttttttg aagtaagcgt cataataacc cgcgcttaag
    27181 gagaatgtac ctaacatgat acggcgtttt acttcttcac cgaatccttc tgaacgtgag
    27241 ttgacatata catcatctaa tgatttcaca ttttcagagc gataaccgta gcggatacca
    27301 tcgaatcgtt gcaaattgga acttgcttct gatgaggcaa tgatataata aacagccaca
    27361 ccgtattttg aatgaggcaa gctgacttct tccacaacag cacctaatga acggaatgtt
    27421 tctgctgctt tcaatacagc ttcttttacg ccaggggcca caccttcgcc taagtattct
    27481 ttaggtaaag caatcttcat tcctttgatg tcgcctgtca gtccctctgc aaaatcagga
    27541 actgaaacgc ctgaagaagt accgtctttt tcgtcataac cgctgatagc tgtcaatgct
    27601 aatgcattat ctttcaccgt acgggtcatt ggtccgattt ggtcaagaga tgaagcaaag
    27661 gcaatcaaac caaaacgtga gacacggcca taagtaggtt tcatccctac gatgccgtta
    27721 aaagctgctg gttggcggat acttccccca gtatcactac ctaaagaaac tggaatttgt
    27781 ccagctgcaa ctgctgctgc agaaccacca gaagagccac caggtacttt tgttgggtcc
    27841 caagcatttt ttgttttctt gaaataagaa gtttctgtac ttccacccat agcaaattca
    27901 tccatgttta gcttaccaac agggatcata tctgcttgat agattttatc catgaccgtt
    27961 gcatcataaa ttggttcaaa attgtaaagg atcttagatg cagcggttgt caagatatct
    28021 tttgttacga tattatcctt gataccaatt ggaataccag caaggacgtt gctttcatca
    28081 atcccttttt catctaaagc ttttgcctgt tccaatgctt tttcttcgtt caatgtaatg
    28141 aatgcctcga cctcaggctc tgtttctttg attcgttcaa atgttgtttt tgtcaaatct
    28201 tgtacagtga tttctttcga tacaagcata tgatgcagtt cttctagaga acgattgtgt
    28261 aattctgtca ttatgcgcca gcctccccat tatcgatgat tgcgggtact ttgataaagc
    28321 cgtcttctgt ttccggcaca tttttcaata attcatcgcg gttccatcca gcttgcgccc
    28381 gatcttgtcg catcacgttt actgtttcaa ccacattcga cgtaaatgga acaccttccg
    28441 tatctacttc ttccagcatt tcaaccatat cgatgatttt acctaattgg tcggtaaaac
    28501 ttgcaagttc ttcatctgcg aacgcaagtt ttgctaattt ggcaacgtgt ttcacttgtt
    28561 cttcactaat cgccatacta ccccttcttt ctaaacgagt taaaaacttt gctctctatt
    28621 ttaacacaag agtgccgtgt ctgaaattgt ttattgaaat ttgtctgaaa aaactcattt
    28681 ttcattcttc tactgagcga cttttagcca atgcatctgc catttgatct tctgtccaaa
    28741 cttcgattcc taattcttgt gctttggtca gcttgctgcc agcatcttct cctgctacca
    28801 cgatatccgt ttttttcgat acgctaccag tcactttccc gccaagattt tcgatcgtct
    28861 cttttgcttc ttcacgagta aatcgtgtta gtttaccagt aaggactact gttttttctt
    28921 taaaaggaga ctcgacttct tgcaattggg catttcgaag ccctttgtat tcgaaattga
    28981 cgcctgcttg ttttaattca ttcatcaatt catggacttc ttcgttactg aaataagtga
    29041 ctacactgtc ggcaatgata tcaccgatcg tatcaagcgc aataatcgac tcatagtcac
    29101 ttttactcaa tgtttctaga tcaccgaaat gttctgctaa aatttttgct gctttcgctc
    29161 cgacatgtcg gattcctaac ccgaaaatca accgctcgac cgaattatct ttgctgttgt
    29221 cgattgctgt caaaatatta tttgctgatt tttcttttat tttgtccaac gtcaataact
    29281 cttcttctgt caatttgtaa agatcagcaa catctgctac tagtttttta tcatacatct
    29341 gttctagtac gcgcggcccc aacccatcga tattcatcgc atttcttgaa acaaagtggt
    29401 tcaaaccttc tttcatttga gcagggcatt taggattgat gcaccgtaag gctacttctt
    29461 catccaaatg gacaagttca cttccacaaa ctggacaatg tgtaggcaat tggtattctt
    29521 cgctgtcttt aggtcgttta tctaacacga cttgcgaaac ttctgggatg atgtctcccg
    29581 ctttataaat cagaactgta tctttcaagc ggatatcctt caacttaata taatcaccgt
    29641 tatgcaggct ggcacggctt actgtcgttc ctgctactcg gactggtgtc atgatagctg
    29701 ttggcgttac tacccctgtt cgaccgactg tccattcgat gttttcgatt agcgtttcaa
    29761 cttcttctgg cggaaacttg taagctgctg cccatctcgg tgctttgata gtaaaaccaa
    29821 gttgatcttg tagcgagaat tcattcactt tgatgacgat tccatcgatt tcatagggca
    29881 aatccacacg tttgtcatga tattcttcaa tgtatgacca cacttcatca atcgaatgac
    29941 atagacgttt ttcccgattc gtgtggaatc caattttttc tagctcttct agcgcatcat
    30001 actgggtttt tgcttgcata ggaccgaaat cagctactgt gtataaaaaa gtgtccagat
    30061 ttcttttcgc tgtgatttta gaatctaact gacgcaaaga accagctgcg gcgttccgag
    30121 gattcgcaaa gatatctttt ccctctgctt ctctgtcttg gttcaattgg acaaatgacc
    30181 gttttggcat gaaacattcg cctcttactt cgatgttcat tggttctttt aatttgattg
    30241 ggaccgaccg gacagttttt aggttttcag tgatgttttc tcctacagtt ccatccccgc
    30301 gagtcgcacc tctcacgaaa tttccatctt cataacgcaa agaaacggaa agtccatcta
    30361 tttttagttc acagcaatag tcaactacac gtcccactgc tttttgtaca cgttgatcaa
    30421 aagctatcag ctcttctttg ctgaaaacgt cgttcaaact gtaaagcgga atatcatgag
    30481 tgactttttc aaaaccttct aatacttttc cgcctactcg ttgagtggga gaatcagacg
    30541 tgatcaaatc aggatattgt tcctcgattg ctactaattc tgcgtattct ttatcataaa
    30601 catagtcttc cactgttggt ttatcttcta cgtagtattc gcgagaccat tggttcagtc
    30661 ttgtacgaag ttcttctgct cgtttagcag cttcgtcaat cgtcatttca tgttccatca
    30721 tttaccctcc actactaagc tttttcaatt ggcgcaaagg cagccaaaag acgttttact
    30781 ccttgacttg ggaaagccac atctagttct agatccttcg acgtcccgct tactcggacg
    30841 actgttccta gaccccattt tttgtgtttg actttatctc caggtttcca gctgttattt
    30901 tcccctccag tagcactttt agagggaaca accgctgtct ctggctgttt atagctatat
    30961 gctgtttttt tagcgaatac aggcgttttt ttaggcgtag gacgcatgcc ttcgatttcc
    31021 agtaactcct gatcgatttc ttctacaaaa cgagaaggtc ggttatattg cgtccgtcca
    31081 tataatgttc tggagaaagc atttgttaaa tacaacgctt cttctgctcg cgtgatcccc
    31141 acatatgcga gacggcgttc ttcctccagt tcgctttctt ccatcaatgc tcgagataaa
    31201 ggaaaaaccc cctcttctag accaatcagg aatacaactg gaaattctaa tcctttggct
    31261 gcatgcaaag tcatcaatgt cacttgggaa gcatcttctt ctaaattgtc aatgtcggaa
    31321 acaagtgcca gatcatttaa gaagaccgtt agtttttctt ctggtgcatc agcgtcttct
    31381 tcattttgct gttcgaattg tttgtcgaat tcttgtgtga ccgttaaaaa ttcctccaag
    31441 ttttcgatgc gtgcttgtgc ttctaatgta ttttggattt ttaagtcttc tagatatccg
    31501 ctacgatcca aaacctcttt cgtcaattct gtcactgtca agtatgggat catctgagtg
    31561 acttcttgga tcatctctcc aaatgcacct aattgctgtc ctgcttttcc accgatattt
    31621 gccagatcca cattttgcgc tgcttcaagc agtggccatt catgaagaga agcaaaactg
    31681 cgtagttttt cgatagatcc tggtccgatg cctcgtttgg gcgaattaac gatacgctca
    31741 aaactgattg aatcttgagg atttaccagc acattcaaat acgctaaaat atctttgatt
    31801 tctttacgat cgtagaactt gtgccctcca accattttat aaggaatatt tgctttcaac
    31861 agagtttctt ccattacacg agattgtgcg ttcgtccggt acaagatggc aaagtcgccg
    31921 taattccgat gattgcttcg aatctcttct tgcatccggt ctacgataaa acgggtttcg
    31981 tctcgttcat tatctgcacg gtagtaagtg atcttgtttc cttctttgtt ttctgtccac
    32041 aagttttttg gttttcgatt gctattgttt tcaatgactt ggtttgctgc gctaaggatg
    32101 tttttcgtgg agcgatagtt ttgttctagc aaaattactg cagcatctgg ataatctttt
    32161 tcaaaatcca agatgttctg catatctgca ccgcgccagc cgtaaatact ttgatctgca
    32221 tctcccacga cgcacaggtt cctaaatcta cctgccaata aattgactag cgtatactgt
    32281 gcgtgatttg tatcttggta ctcatctaca tgaatataat ggaatttgtt ttgataatac
    32341 gtgagtgaat caggatgttc ttcaaataat cgaatcgtat tcatgatcag gtcgtcaaag
    32401 tccatacatt gattatattg aagctctttt tggtaagcag cataacattt tgccgcaatc
    32461 tcttcgtaat aactgccttg catttttgca aaatcctgag gggtctgcag gctgtttttt
    32521 gcttgagaga ttgttcctaa tatacttcga ggatcatatt ttttcggatc aatgttcagt
    32581 tcttttagta tccgtttcat caaggtcagc tgttcagaag aatcgatgat tgtaaagttc
    32641 cggttatacc cgataaaatc aacatctctt cttaaaatac gcacacacat cgagtgaaaa
    32701 gtcgataccc agacatcttc gcctccagat gcgagaatcg cattgacacg ttctttcatt
    32761 tcttttgcag ccttattggt aaaagtaatc gctaggatgt tccaaggatt gacttctttt
    32821 tcctcaatca aataggcaat gcggtgtgtc agcactctcg tctttccact tcctgcacct
    32881 gccattagca gtaatggtcc gtcagtgtga agaacagctt ctttctgacg ggggttcatc
    32941 ccgtttaata attcagcttt ggatgacatt aacaacatcc tttcttttat caatcttgtt
    33001 aattatagca ttttcttggc tttcattaaa ctagctagtt caaaatcatt tgtttctttt
    33061 tatggatttt tccttgtcaa ttcgttgatt tcgcgctaaa ttaaaagaaa gcgaggcgtt
    33121 tgaatggaaa aaaaaggaaa aatcaagaaa ttagataaga ctcagatata ttttattcta
    33181 aaaggaatat ttgttggact gctgacagga atcgtcgtta gcctgtttcg attatctatc
    33241 gaaaagctaa gcgatttagt tcgaagtatc tatgaaatga gtcgggaaca gccgatttac
    33301 ttaattggcc tagctatttg ctgcatcctt gcagcatttt tcgtgggtta tctggtcaaa
    33361 aatgaaccgg atatcaaggg aagcgggatt ccacaagtag agggacagct tcgcggggaa
    33421 ttatcaatga actggttctc tgttttatgg aaaaagttca ttggcggtgt actttcagtt
    33481 ggtgcgggcc tttttctagg tagagaagga ccttctatac agcttggcgc atccattgga
    33541 caaggagctg gacaattgtt tcggagtcca tcttcagaag aaaagatttt aatttctagc
    33601 ggtgcaagta gcggacttgc agcagcattc aatgctccta tcgcaggatt actctttgtt
    33661 ttagaagaaa tccatcactc cttttctcca cttgtttggc tgacatcatt tgcttcagca
    33721 atcactgcta acttcgtctc tctttacttt ttcggcttga gacctgtttt atatctaggt
    33781 gaccttcctt ctttgccgtt gaaatattat ggttccttag tgatcttagg agtacttcta
    33841 ggcatcttag gttttattta tcagaatgtc ttgctggctt tgccaaaatt ttacaaccga
    33901 ttgcctttac cagcttattt tcacgggttc gttcctttct tgctgatttt gccaattggt
    33961 tatttatggc ctagtactct aggcggaggc aatcaaatcg ttttagcttt tggacatgct
    34021 tccttgccaa tcattatgat tatcggtttg tttgttcttc gattcgtttt ttccatgatt
    34081 tcttacggtg ggggtcttcc aggggggatt ttccttccga tattgacatt gggggcttta
    34141 atcggtagct tttatggaaa cattatggtt gatttcggga tggatccaat ctacatcaag
    34201 gattttgtcg ttattgccat ggctggttat ttcacagcga ttggaaaagc accgctgaca
    34261 gcaattattt tagtgacaga aatggttggc tctcttaatc atctgatgcc tttaggattg
    34321 gctgctcttg ttgcttatat cgtcaatgac cttctcggcg gtaatccaat ttacgaatca
    34381 ttattggaac gtctacttgg aaatactcag accgcctcac taaaaggtgc aaggacaact
    34441 tttgattttc cagtaacggc agagagttct ttagacggat taatggtacg agacttcaat
    34501 tggcctaaaa atatgctgct aatctctata cgcagaggaa atcaggaaat cttgactcac
    34561 ggtgatacga tcatgaatgt aggagatatt ttggttatct tgactgatga agcaaacttg
    34621 ccaagaatca agcaggaaat cgaggctaaa tcttctatca caaatttgaa gcaatcattt
    34681 taacgaacat ggaaaaacta ttttacaaca actattcatc tacactactt gattctatat
    34741 gattctataa aaaaagaaga ggctgggaaa ac
//
LOCUS       DAIGSZ010000028        34118 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.028, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000028 DAIGSZ010000000
VERSION     DAIGSZ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.028"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(99..1229)
                     /locus_tag="NOB31_001379"
     CDS             complement(99..1229)
                     /locus_tag="NOB31_001379"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HCI0973595.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="NOB31_001380"
     CDS             complement(1878..3080)
                     /locus_tag="NOB31_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0973596.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="NOB31_001381"
     CDS             complement(3140..3343)
                     /locus_tag="NOB31_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HCI0973597.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="NOB31_001382"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="NOB31_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="NOB31_001383"
     CDS             4880..5692
                     /locus_tag="NOB31_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973598.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6868)
                     /locus_tag="NOB31_001384"
     CDS             complement(6716..6868)
                     /locus_tag="NOB31_001384"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCI0973599.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="NOB31_001385"
     CDS             complement(7059..7937)
                     /locus_tag="NOB31_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0973600.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="NOB31_001386"
     CDS             complement(7976..9094)
                     /locus_tag="NOB31_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HCI0973601.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="NOB31_001387"
     CDS             complement(9091..11190)
                     /locus_tag="NOB31_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HCI0973602.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="NOB31_001388"
     CDS             complement(11241..12062)
                     /locus_tag="NOB31_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0973603.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="NOB31_001389"
     CDS             complement(12059..12868)
                     /locus_tag="NOB31_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0973604.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="NOB31_001390"
     CDS             complement(12889..13383)
                     /locus_tag="NOB31_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0973605.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="NOB31_001391"
     CDS             complement(13395..13883)
                     /locus_tag="NOB31_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0973606.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="NOB31_001392"
     CDS             complement(13960..16656)
                     /locus_tag="NOB31_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0973607.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="NOB31_001393"
     CDS             complement(17084..18157)
                     /locus_tag="NOB31_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0973608.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="NOB31_001394"
     CDS             complement(18154..18981)
                     /locus_tag="NOB31_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973609.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="NOB31_001395"
     CDS             complement(18982..19788)
                     /locus_tag="NOB31_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973610.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="NOB31_001396"
     CDS             complement(19800..20885)
                     /locus_tag="NOB31_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0973611.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="NOB31_001397"
     CDS             complement(20902..21444)
                     /locus_tag="NOB31_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0973612.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="NOB31_001398"
     CDS             21702..22691
                     /locus_tag="NOB31_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCI0973613.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="NOB31_001399"
     CDS             22688..23425
                     /locus_tag="NOB31_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HCI0973614.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="NOB31_001400"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="NOB31_001400"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HCI0973615.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="NOB31_001401"
     CDS             23989..24621
                     /locus_tag="NOB31_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0973616.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="NOB31_001402"
     CDS             24706..25353
                     /locus_tag="NOB31_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0973617.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="NOB31_001403"
     CDS             25358..26341
                     /locus_tag="NOB31_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HCI0973618.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26744..28258)
                     /locus_tag="NOB31_001404"
     CDS             complement(26744..28258)
                     /locus_tag="NOB31_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HCI0973619.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYSVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="NOB31_001405"
     CDS             28396..29202
                     /locus_tag="NOB31_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973620.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="NOB31_001406"
     CDS             complement(29377..29946)
                     /locus_tag="NOB31_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0973621.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="NOB31_001407"
     CDS             complement(30029..32089)
                     /locus_tag="NOB31_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HCI0973622.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..33844)
                     /locus_tag="NOB31_001408"
     CDS             complement(32366..33844)
                     /locus_tag="NOB31_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973623.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT        10254 a         7082 c         5748 g        11034 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttaccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacagag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctctttta
//
LOCUS       DAIGSZ010000029        34105 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.029, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000029 DAIGSZ010000000
VERSION     DAIGSZ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34105
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.029"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            5..403
                     /locus_tag="NOB31_001409"
     CDS             5..403
                     /locus_tag="NOB31_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCI0973624.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1081
                     /locus_tag="NOB31_001410"
                     /pseudo
     CDS             387..1081
                     /locus_tag="NOB31_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
     gene            complement(1675..2562)
                     /locus_tag="NOB31_001411"
     CDS             complement(1675..2562)
                     /locus_tag="NOB31_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCI0973625.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2747..3586
                     /locus_tag="NOB31_001412"
     CDS             2747..3586
                     /locus_tag="NOB31_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI0973626.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3782..4756
                     /gene="sgrA"
                     /locus_tag="NOB31_001413"
     CDS             3782..4756
                     /gene="sgrA"
                     /locus_tag="NOB31_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HCI0973627.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5054..5410
                     /locus_tag="NOB31_001414"
     CDS             5054..5410
                     /locus_tag="NOB31_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973628.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5413..6570
                     /locus_tag="NOB31_001415"
     CDS             5413..6570
                     /locus_tag="NOB31_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973629.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6596..7036)
                     /locus_tag="NOB31_001416"
     CDS             complement(6596..7036)
                     /locus_tag="NOB31_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCI0973630.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7196..7702
                     /locus_tag="NOB31_001417"
     CDS             7196..7702
                     /locus_tag="NOB31_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0973631.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7870..9783
                     /locus_tag="NOB31_001418"
     CDS             7870..9783
                     /locus_tag="NOB31_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HCI0973632.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9788..10789
                     /locus_tag="NOB31_001419"
     CDS             9788..10789
                     /locus_tag="NOB31_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0973633.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10991..11197)
                     /locus_tag="NOB31_001420"
     CDS             complement(10991..11197)
                     /locus_tag="NOB31_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HCI0973634.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11843..12691)
                     /locus_tag="NOB31_001421"
     CDS             complement(11843..12691)
                     /locus_tag="NOB31_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0973635.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12690..13757
                     /gene="gnd"
                     /locus_tag="NOB31_001422"
     CDS             12690..13757
                     /gene="gnd"
                     /locus_tag="NOB31_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HCI0973636.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13759..14760
                     /locus_tag="NOB31_001423"
     CDS             13759..14760
                     /locus_tag="NOB31_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HCI0973637.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14757..15041
                     /locus_tag="NOB31_001424"
     CDS             14757..15041
                     /locus_tag="NOB31_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HCI0973638.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15074..15871
                     /locus_tag="NOB31_001425"
     CDS             15074..15871
                     /locus_tag="NOB31_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0973639.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15885..16718
                     /locus_tag="NOB31_001426"
     CDS             15885..16718
                     /locus_tag="NOB31_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0973640.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16736..17593
                     /locus_tag="NOB31_001427"
     CDS             16736..17593
                     /locus_tag="NOB31_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0973641.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17615..18124
                     /locus_tag="NOB31_001428"
     CDS             17615..18124
                     /locus_tag="NOB31_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0973642.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18161..18562
                     /locus_tag="NOB31_001429"
     CDS             18161..18562
                     /locus_tag="NOB31_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973643.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18674..19027
                     /locus_tag="NOB31_001430"
     CDS             18674..19027
                     /locus_tag="NOB31_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973644.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19061..19504
                     /locus_tag="NOB31_001431"
     CDS             19061..19504
                     /locus_tag="NOB31_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI0973645.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19521..20606
                     /gene="uxuA"
                     /locus_tag="NOB31_001432"
     CDS             19521..20606
                     /gene="uxuA"
                     /locus_tag="NOB31_001432"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCI0973646.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20599..21312
                     /locus_tag="NOB31_001433"
     CDS             20599..21312
                     /locus_tag="NOB31_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0973647.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21519..21668)
                     /locus_tag="NOB31_001434"
     CDS             complement(21519..21668)
                     /locus_tag="NOB31_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973648.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22064..22264
                     /locus_tag="NOB31_001435"
     CDS             22064..22264
                     /locus_tag="NOB31_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0973649.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            22832..23395
                     /locus_tag="NOB31_001436"
     CDS             22832..23395
                     /locus_tag="NOB31_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973650.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(23456..23821)
                     /locus_tag="NOB31_001437"
     CDS             complement(23456..23821)
                     /locus_tag="NOB31_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973651.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(23897..24142)
                     /locus_tag="NOB31_001438"
     CDS             complement(23897..24142)
                     /locus_tag="NOB31_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0973652.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(24212..24466)
                     /locus_tag="NOB31_001439"
     CDS             complement(24212..24466)
                     /locus_tag="NOB31_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973653.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(24630..24953)
                     /locus_tag="NOB31_001440"
     CDS             complement(24630..24953)
                     /locus_tag="NOB31_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973654.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            25140..25213
                     /locus_tag="NOB31_001441"
     tRNA            25140..25213
                     /locus_tag="NOB31_001441"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25174..25176,aa:Ile,seq:cat)
     gene            complement(25598..26095)
                     /locus_tag="NOB31_001442"
     CDS             complement(25598..26095)
                     /locus_tag="NOB31_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0973655.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(26135..26944)
                     /locus_tag="NOB31_001443"
     CDS             complement(26135..26944)
                     /locus_tag="NOB31_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0973656.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            27278..28135
                     /locus_tag="NOB31_001444"
     CDS             27278..28135
                     /locus_tag="NOB31_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCI0973657.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            28128..29030
                     /locus_tag="NOB31_001445"
     CDS             28128..29030
                     /locus_tag="NOB31_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCI0973658.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            29063..29413
                     /locus_tag="NOB31_001446"
     CDS             29063..29413
                     /locus_tag="NOB31_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI0973659.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            29462..30385
                     /locus_tag="NOB31_001447"
     CDS             29462..30385
                     /locus_tag="NOB31_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCI0973660.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            30463..31356
                     /locus_tag="NOB31_001448"
     CDS             30463..31356
                     /locus_tag="NOB31_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0973661.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            31394..31957
                     /gene="amaP"
                     /locus_tag="NOB31_001449"
     CDS             31394..31957
                     /gene="amaP"
                     /locus_tag="NOB31_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCI0973662.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            31971..32159
                     /locus_tag="NOB31_001450"
     CDS             31971..32159
                     /locus_tag="NOB31_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCI0973663.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            32172..33074
                     /locus_tag="NOB31_001451"
     CDS             32172..33074
                     /locus_tag="NOB31_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI0973664.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            33106..33348
                     /locus_tag="NOB31_001452"
     CDS             33106..33348
                     /locus_tag="NOB31_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0973665.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(33604..33975)
                     /locus_tag="NOB31_001453"
     CDS             complement(33604..33975)
                     /locus_tag="NOB31_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973666.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT        11864 a         5415 c         6855 g         9971 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcagcgata acgttaggta aagagctact
      961 agatcaagta ttagagatgc cctcgattga taaagcagtg aggggcttcc aagaagattg
     1021 ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa aaggtcgctg attacttctg
     1081 aatcaatttc tccataaaat aaacgatagc cttctcgaaa actcgaggag gctatctgac
     1141 gattcaatat tcattaattt aaagtttggg tgactattac taactattac ttatttctca
     1201 tttaaacgat gtattcccta acctctaata catccttgta actctgaagt tacgccagtt
     1261 ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata aaaatatctt tcgtgtttct
     1321 ctagtataac agaataagaa gaacaagtcc agaagggata tttttagtct tttttaaaat
     1381 aacttttcag tcgagtttga gtttatgata gttgtttttg aagcgatacg gcaagtgaaa
     1441 aaatagggaa gcatgaaaga atctacttaa tggcgcattg attcatgtga tagaaataaa
     1501 aaactttttt aaattatatc ctcatgattg taacaaatcc agtgatttgt tttggtacaa
     1561 ataaaaaaag gccccgatga agttgtggca aaagtggttt gcctcaaaaa taagaaggaa
     1621 tttccaaaaa tcacttctca aattttgcca catccccaat tgggtcaaat ttgtttattt
     1681 gaatatattt tttacataag gatctttaat agttacattg tcttttttca tcactttacg
     1741 gattgtttta tccatgaatt ccgtatcaag agtttttgct tcggtagcaa ttttttctag
     1801 ctcagatttg tatttgtctt tattagaacc tttatcctgt ttttttacca tttttactag
     1861 ataatagctt tgctgataag tcgttggatc tgttacagga atgatatcag aaacttcccc
     1921 gttttttagt ttaaatgctg ctttttttac ttcagtagga atctctggat tggttgaatc
     1981 aaaattcatt tttccatcag tttcctttaa tgttttattt tttccataag cttgaacaag
     2041 cttggagaaa ttttctcctt catttgcttc tttttttgct ttatctgctt cttctttagt
     2101 cgaaaataga atgatctgtg tactaacttc tggatagaat tctttccaag cagtgtctag
     2161 atctttatct gttaatttta cattggcttt caaaccgtat tggaaagcca gcatctgttt
     2221 aaagagtttc ttatatgtct cttctgtttg gccaactgct tttaattgtt ccttgtagtt
     2281 tggaccgagt tttttgattt gttcattata ttcttttgtt acttcctttg aagaaatctc
     2341 ttttccgtat acatcatcaa atgctttgaa gacaatcatt ttttttaata gtgtttgatt
     2401 atttgattta acttttgggt tatcataaaa atcctgaact gtaagtgttc cacctttaaa
     2461 cgttgcaatc gtttcattgg acttgctaca acctgagaat agtaaaattg cacatgctga
     2521 aaggcacata attagtagtt gttttttcaa aaaatttccc atcctttcct tattaaaaac
     2581 agtctaacag aagaattagg gagacagtct ttcattttcg taaggttgct gtagatattc
     2641 ttagttcgta aaaatctatt ctctctatga tggagaacat ttacatagtt ttcacgagac
     2701 aagaaagaaa agggttgtta aacttaatat aaaggaggga tgaaagatga tcaggattat
     2761 tcggttgatt ggatctgttt taatagtctt tgttggtttt gttttaggaa ttcttgtcaa
     2821 taatgcactt gcggatatgt ttattggaaa tagtgaatgg attggagcaa ttgccggtac
     2881 ggtcggacat ttagctgttt ttttactagc tttatttctt gctagtaagg tcgaaggaaa
     2941 aagaatagaa gattatggtg tttctgttcg aggaaaagac tgggggtatt tagcgggagg
     3001 tctcgttgtt ggaattggag tgtttctgct tattactagt ccattatatt tgacgggggc
     3061 gtatcggtta gattcaggaa acgcaaacat tgtgccgctg ataacgagtt ttattttatt
     3121 tattgcagtg ggggcatcag aagagctttt attccgtggc ttttttcagc atcagatgct
     3181 tagatttggt ccgttaatag caatgattgg atctgctgca ttatttgctc ttttgcacgg
     3241 attgaatcct aacatgacat ttctggcagt tttcaatatc tttttagcag gttgcttttt
     3301 cagcgcactt atctacagta caggaagttt atttacggct attggtgctc atattacttg
     3361 gaattggaca caaggagcta ttttgggtat accagtcagc ggaacgcaag aacaaggttt
     3421 tttctccact ctgatccaat cgcaaaatac aataattact gggggaaact ttggggctga
     3481 agcatctata tcaactacat tattcttgtt agtcttgatt gttggtttgt tactctatgc
     3541 atataaaaca aagcggatga agaaatacac tgctgtttat caataaaaga tgaagaaagc
     3601 aaggctgata tcggtcttgc ttttttaagt ctgtcattga ttaaacgaaa aagtaaacaa
     3661 attcaagcga atacacgaca tcttttgtta gattttcaca actgactgtc gtgttctcat
     3721 cattttcatt ttatataatt cctttatcaa atagaaggta attatatgga gagtgataga
     3781 aatgaagaaa acagcgaccg tattatttgt tattcttggg ctgagtataa ttgcagcaat
     3841 gattggaatc agtacttctg caaatgaacg ggcaaatgag aatctttcat ttactgtgaa
     3901 aactgatcgg attgtttatg acatgacaca acaagtcatt actattccag tcaaaccaaa
     3961 caaaagcgtg aatgctagtg atgtacatgc tgttctaaca tatggttggg atggtaatgg
     4021 aagttcagaa aaagttattg gggaagttta tttaaaagac gtacaatgga ccgctggtat
     4081 tgagtataca ataatgattt ctgcagaact atcgattgat gagatcaaga gtaaagataa
     4141 agttgatttg attgtttttt atgatggaca gatgacgatc acggagaatt tgaaaccaag
     4201 cagttggaca gttgttggac cgccaagcag tacggatagc acaagtagtg aaagcagtac
     4261 agaaaacacg agcggtgaaa gcagtacaga gagtacgagc agtgaaatta gcacagaaaa
     4321 cacgagcagc gaaagcagta cggagagtac gagtagtgaa agtagcacag gaagcacgag
     4381 cagcgaaagc agtacggaga gtacgagtag tgaaagtagc acaggaagca tgagtagtga
     4441 gagtagcaca ggaagcacga gcagcgaaag cagcacagga aaagtaaata atgaacttga
     4501 tttggtacct atcataccaa ctaaggaaca aaagagaaat gcagggagca acctaaaaag
     4561 tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat catcaagaaa aagcgaaaga
     4621 aacagataat agaaaaagcg atttaccaga aactggtagt agaaccttga acaagctaat
     4681 tacatggatg ggtgtgttac tcattttgat tgtaggagca agctattttc gttctctctt
     4741 ccatcgagtg aaataaagaa taaaagcaac agatctaaaa ttgaataaaa cgatagattt
     4801 ttgagtgaat atttcattcg agagtgctgt attgcctggc gaagttgtag ctttgccaga
     4861 tctatttttg tttactaaca tatttgagaa acaggaaata acaggaacac aaatggaaaa
     4921 taagagcaag aataattgac aatgcacact gcgcatggta gtatctctga aaaatcagta
     4981 acgaatctat ttgtacgtta ttcatgtagc tgtcggaata agtctaaata atagataaaa
     5041 aggagtatgt actttgtttg aagaatttat tgatatcaat gaaaggcaag tatatcaatt
     5101 tttgaactat tgttatgaaa gagacgagaa attatatgtg gtgaaggata tcgctttaga
     5161 tctaaactac accctggcta agatgaattc ggtgattcaa caagcagaat cgttttgcga
     5221 aaggtatcca gaatataaat tatcttttct ttcagaaaac aagatgataa aagtcgagtt
     5281 ttcttctcag tttttactga gtaaagttta ttctatactt ttagagggaa cgattggtta
     5341 tattttactg gattcacttt acaaaggtac ttatcaatcc ttagaaaatc ttagtcaaaa
     5401 aattatataa gtttgcgtac gattcaaaga aaattaagag aacttaatac tattttgaaa
     5461 aactatcatt tatcttgcag cttgaaaaaa ggtaatccga tagaaggaga agaataccgt
     5521 atccgatact tttttcactt gatgtattgg cagtcattcg acgaaaatca ttctgatata
     5581 ttatcaagta taaaaaataa acgtcaacta ttagaaaaat ttgcgaaaca tgcgccatat
     5641 acgcgtagta tagatagaaa gaaatggatc agcctactaa gaatttcgtt gcaacgaatg
     5701 aaacaaggcc actcgattac gtatgtccca gaagagatga acaaatttgt gcatccattg
     5761 ataacaaaag aagagtttac gcattacata ctagagcctt tttttgaagc aaacttctgg
     5821 tcgatgaatc acatcactcc aacagagcaa gcttaccttt attttatgtt tggtgtaatg
     5881 aacacctatt tggaagaaga tttgttggat actccagata aagtacaaga aagttggggc
     5941 tggattgaat cgtctattgt agaaaatttt gaaaaaaact tcaagatttg ttttacaact
     6001 tcagaaaaaa attatctata tgtcaatttg gcaatgatcc atttgtattc aagggttttt
     6061 gggacaaaaa agaaggtgga tgcttttgga aaatcagcag aagacagaga ttttcagcat
     6121 atatttccag tgatgtatcc aatcatgcaa cagtttttta gtggggtagc tcgcagaatt
     6181 ccagagctta atacttatta tgaaaagaac agacggttga tttttcaata ctgtatgtta
     6241 gtcagggata tttttataaa acacgaacaa cctgtcatat tctatattca atcaaagtat
     6301 ggtaaaacac aggaattatg ggcaaagaaa aggatattat ctatgactga acgcccaata
     6361 aaatatagtg catccgctga tcagttacct gatattgtca ttagcgatta tcctatcgac
     6421 aaaaaggcat atgatcaaac gaatacacag atattttact ggaatggaca acctacaaaa
     6481 aatgattggg cgcgtctgaa agctgaaatc ataaaaatca ggaatgagaa aaatagatcc
     6541 atattggaaa aattggattt cgttaattaa gaaaagcaga ttgtttatgc caaaattaag
     6601 acattgcaaa aagattattt tctttaaaat cgacaagatg accagaaagc aagagttcgt
     6661 tgagctcttg ctttctttta gttttagaaa ggaacatcct gattttatct tcgctaaatc
     6721 cagtcaaaag ttttgcagat tggtcgtaga taatcggttt tttcaataaa gaaggggatg
     6781 tacgaatctc aatatatagt tcactcaaac tgagttcatc tattctgtga acaagatttt
     6841 tataactaat agaatgagta gagagcattt cggtcacgcc gttgtttgtc aattttagta
     6901 agtggataaa ttcatttttg gttagtggtt gacgaattaa gttctgttcg ataaacggta
     6961 tatcatggac gataagccaa cgttttgcgc gtcttgaaga cgagcagcca gaacctgtat
     7021 acaatttaat catcatacat tcctccaata gctaagtatt tatgaaataa taacatgaag
     7081 aaatagtcga aaagtgccat ttagaggtgt aaaataagaa aatgttgtca cgtataatgg
     7141 aactagctag ataagaaata ctattaaatc aagaaaaaag aaagaaggca caagtatgtc
     7201 aaacacagcc gacgcaatag tagtgatcga tttacaaaaa ggggtatgtt ttgattcttc
     7261 gccgatacac gaattagaaa cagtgacagc attagtgaat aaaagaatca aaacatacga
     7321 aacgattggg aaaccagtta ttttcgttca acacgaagat gctcaattag tgccacaaac
     7381 aaaaccatgg gagctattgt cggaattatc tattcctgag cacagttatt ttgtgagaaa
     7441 aacccatgcg aattcatttt ataagactaa tttgagtgtt ttattaactg aattggactg
     7501 tcattcgatc gaattatgtg gggcacaagc agagtattgt atagatacga ctgtgaagtt
     7561 tgctcatgga ttaggatacc agcttatgat gtgtagagga gcaacgacaa cttatgataa
     7621 tccttttatg aaagcaaagg aaacaatcgc tttttacgag aaaatttggg ataaacgatt
     7681 tctgacattt ttggagcaat aagttgtttc ttcgtttaaa aaaagcagaa tggatactgg
     7741 tttatccatt ctgctttatt acgtaaaatg agaaaataat cctgttctat ttttatggga
     7801 taaaccattt attttttgta taaaaaatgt ttgcgtttac atataattct cctagaaaca
     7861 taaaaaggag tgaatagctt gagaacaaaa caagtattaa agggagcgtt ggtcatctta
     7921 tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg gagagagcat ttcttccgaa
     7981 tcggaatctc gggaggtaga aaccacagaa actactgatg ctggaaatga aacgaaatcg
     8041 agtacttcac aaacagaaac aaatactgaa acaacggttg agacatctgt tactagcaca
     8101 gatcaagaaa cgaccgctac cacagataac caacaaacag aagaagcaac agctacaaaa
     8161 atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca aagagaatgg gacagaaaat
     8221 gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat atttgaatta cttcggtaaa
     8281 cagatgacag aaatacttaa tggaccaaca gaagacatca agtcaaaatt aatagagtta
     8341 ttagtcactg agcttgctgt taatgattat ggtgtagata aagagattat caaacatctg
     8401 attgctactt atctattgta cgatatcgct tttgcaaaaa acagtgtgtt gatgtcgatg
     8461 cttggaggta cagatgatgg gacaacgcct acagaaaaca caggcttcta tccaaataca
     8521 aaacaacttc atcaaactgt actaaacaaa caagatggca aaatgatgga tgtatatgca
     8581 tattatgtcg atcaaggttc agataaaaca gtcatgatcc atggcggatt tcgagggaat
     8641 tggaataacg ggatcgttac agaagaatac aatgattttt ataaggccgg gtataattta
     8701 ttatttgttg attccagagc gactggtaat agcggaggcg attatgtgac ctatggacaa
     8761 tatgagtcag atgacgtcct ttactggata aatcaagaag ttcgagagcg gccatctcaa
     8821 aagattttac tttatggtgg ttcgatggga gcagctacga tgatgtctgt attagcgaaa
     8881 gatattcctg tcaatgtcaa aggaattatt gaaaattgcg gatttgcatc aattgatgaa
     8941 caactacgtt ttacgtacag ccagacagta gcccccgcac taccggatgc cataaaaaat
     9001 cagttagaca tcattgggga tcaagagcat gaagatttat ttatgggcct tttgaaacaa
     9061 tactattttg atcaggagat gcatttggat acaaaagctg ctctacctac gattggaatg
     9121 tcagattcat tgcctaaatt gattatccat ggaacagcag atgatgtagt acctgtgtct
     9181 aacgcgcaaa aattatatga gttatcagga gggtataaag atcttttatt agtagaagga
     9241 gcagggcatg gaaaggcaca ggaagttgac catgctgcct acacgaaaca tgtaacggac
     9301 tttttgaaag tagtgttcca tgatcagata aacgtaaagt atgtggatga aaacaataaa
     9361 agtctactca aagaccagga cgaaatccag ctttacggag cttatggaga aaattatatg
     9421 acagagcaaa agacattcga aggatacgaa ttagcaaatg ttgaaggacc gactgaaggg
     9481 atttttaatg agacgatacc aactattatt ttctattaca aaaaaatccc agtagctcca
     9541 ccaaaaaagc aagatccgac agagaatgca gacaataagg gaaagaatga acctcgagag
     9601 gatcaatcaa gtgatgatac gcaaccgatt cagatgacag tgaaagtaca aaaaaagaca
     9661 gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga aacattcgct tctcatttat
     9721 tcaggtggat ttttatctgt tagcacgatt atcacatgga tttggcgaag aaagagaggg
     9781 taaatgaatg aaatggttca agcgaatagt gattgcagta ccagttatca tcgtagttat
     9841 tttagtcact gtatttttga ttaatcaaat cacaccaaag ccgattagct tgcttgttag
     9901 aaaacaattt gacacaagtg aaaaagaaca agtatatgcc cgaccagatg atttccagca
     9961 aaaaatcgaa caaatcgata taaaaaaaga aatatcctat ccttcaaagt acaaaaataa
    10021 taatatggat atctacacac cgaaagtgga aaagaaaaaa ttaccgattc ttttctggat
    10081 gcatggaggc gcatatgtag gaggggataa aaatgattgt cgtgattatt tggaatatct
    10141 atgttcagac acgcagcaaa tcatcgtaaa tatagattat gaacgatcac cggaagcaaa
    10201 acatcctaca ccagttatcc aattgaacga agccattcaa gcagctaaaa aagagataaa
    10261 agatcaagca gattggtcga atatttcgat tggtggaaat tcggcaggtg cacaaattag
    10321 tggagaatat ttgttagcac ttcaaaatga agaaattaaa aaagctgatc atcttgatcc
    10381 gactttggag aacaagcaga ttacgaagtt tatttctttg tctggtctgt tggatccttc
    10441 tgcacttact caagtaagtg ataaaatctc tagctttctt tatgaaaaat gtggatgggc
    10501 ttactttgat aataaggact ttgaacaatc agagaaggtc aaaagtttag ccttggtcag
    10561 acatgcggat cgttggacgc aaaacacatt cttaacggat ggaaatacaa atacgtttac
    10621 gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg ggggtgaaag tcacaaaagt
    10681 agattatgcg gagaaaaatg ctgttttgaa ccatgaatat cagtttgatt tcagcaataa
    10741 acaagcgcaa gaaacatatc aaaagttagt aatgtttttc aaggagtaaa gtcttatgat
    10801 gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca aggagcaatt tcaataaaca
    10861 agcttttcat ggtttatgaa tattgtaact tgtgactgag gagttagaga tggcaagggg
    10921 caccttttat tcgaaatttg ggaatatcac acgattattg tcacgatctc ttttacgtaa
    10981 attttataag tcagatttgt tgttttgatc gtttaaaaaa agcaacaaat ccgaagcctg
    11041 cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa gaatgctggt tccactaata
    11101 ttccgttgtt attgatataa ggctgggaac aaagatgaat agcaaataaa atcaatgcac
    11161 tagcgaaaaa aagcaaagaa atatggatag ctttcataag cagcacctcc ttttttataa
    11221 ttgtatgata aatagattaa gaatctataa atgtgacaag tttgttagga tgtgaataaa
    11281 atgatcatct agcgaacttg aaacaaagat ggctaatgat aagcaattaa tgattcagca
    11341 atcagatagg tacaaagttt accatcatac gtctagacca ataatagaaa atatgggaat
    11401 ataatagaaa agatttagga tacccccaaa agaatttccc caaaaattcg atgtatccta
    11461 aactttttta ttttacataa caatcatatc aactgtgaaa taaaattaca aatgataacc
    11521 taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt aattcaccaa aatttttttt
    11581 aattttttag aaaataagaa acaaaaataa taaaaaaaag aaaagataaa ttttttacta
    11641 ctgtatacta actttgttat cgcatctaac aagtaactcg aataatacca atacaacctt
    11701 ctccaaagat gcgatgacat acgttctaac ccaccgacta ttgatgttct gtaccaccct
    11761 tgcagaacca aaaaagccac taccaaatat ttggtagtgg ctttttttgt tttatggatt
    11821 tttcgctttt tctgttatgg tgctattctt tgatttcaga aatagtatgt cgaactttag
    11881 cgatagaacg acgtgattct ttttcgttgt aaaacatcaa aatcacatat agagagtcca
    11941 aaatgcttag ttgagaaata cgggaagcta aagcttcaga tcggaattct gtttcttcag
    12001 aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga agaattagct tggctagtaa
    12061 taacgattgt ttttgctcca gtttttctta cggtttcagc aatatggatt gtttcttttg
    12121 attgccctgt gtgagaaatc aaaacagcac agtctttttc cgtcaataaa gaagcttcca
    12181 tcaattgaat atggtaatcc gtgctgtgag aagttgcgat aggggaacgc aaaaatttat
    12241 gataagcgtc agttgctaca atctctgaac cgccaacacc gaaaaaatag acacgtttag
    12301 attcattgat aatagtagcc gcttttttta gatccttttg ttgtaacaac ttttttgtgt
    12361 catttaaagt tgaaatacta gactcgaaca ccttttgcgc catagtgagc tcagtatctg
    12421 ttttctgaat attttcgtgg atagaaatag cagatagatc attttcttgg atcaacatgg
    12481 ccattttaaa atctttaaat ccattataac caagtttttt tgtaaattga aaaaaagtag
    12541 agtcagcaat gcccagttca cttgctaaat tgctaatagg actatgactt actttgcttg
    12601 gattttctaa aatataatcg gcgatagcct gttcttttgg gctgaagtcg ttgtacattg
    12661 ttttgatttg tagtcttatg gagacgctca tgagaattcc tcattttcat aataagatta
    12721 tcattttttc cgttctcatt aatgttaaag atacaaggag agtaggaaaa aatcaaacaa
    12781 aaaatatttt tgtaaaatct atttacaaaa aaattttttt gtataatgag ggtataagaa
    12841 atggaggcgc tatcatggaa attggtgtaa ttggtttggg aaaaatggga ttgaatttag
    12901 ctttaaactt aaaagagcac catcacaaag tacaaggact cgacatttca agtacagctg
    12961 ttagtcaggc aagagaaaat gacattcctg cttatcaaga gatctctgaa tttctagcta
    13021 cttttgagca gaaaaaaatc atctggttaa tgcttcctgc tggagagata accgaaaaca
    13081 tgttaagaaa actttttcca aaactcggac caggagacat tattattgaa ggcggaaact
    13141 cttattataa agattcaatc cgtcgagcag aagagtttca gaaaaatgaa atcggttact
    13201 tggattgtgg gacttctgga ggaatcgaag gagcacgaca tcaagcctgc ttaatgattg
    13261 gaggagataa agaaactttt ctatccgtgg aacaattatt caaagatgta gcaattgaaa
    13321 gaggatatct gtatgctggt gcatccggaa gcggacactt cttgaaaatg atccataatg
    13381 gaatcgaata tggaatgatg caagcaatcg gtgaaggatt ccaacttgta caaaaaagtg
    13441 agtatgcttt tgacttggaa caagtcgcac gtgtttggaa tcatggttcg gtgattcgcg
    13501 gctggctgat ggaaatcatg gaagatcagt taaacgaaca tcccaattta agtaattatc
    13561 ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt tgaaacagcg ctagaaatgg
    13621 ctgttccagt tccagtaatt gcaactagtt tgttcatgag gaatctttca caggaagaag
    13681 atagtttttc agcaaaagta gtttcagcac taagaaatgg gtttggcgga catgaaatag
    13741 ttgaaaaggg tgagtaaaat gccagattat catatagcaa tcgttaattc cagcagtttc
    13801 ggaagagtct ttccacacca cttggaaaga ttaaagtcag ttggagacgt tcatttcttt
    13861 actgttgatc aagagattcc aggaaaagaa ctagcggagt tacttaaagg attcaatatc
    13921 attattgcaa gtgttacgcc attttttcga cgagattttt ttgaaaacaa agatgaactg
    13981 ctattgattt cccgacatgg tattggttac aacaatattg atttaaaagc agcaaaagaa
    14041 caccagacaa tcgtatctat catacctgct ttaattgaac gaaatgctgt agcagaaaat
    14101 aatataacta atttgttgtc catgcttcga cgcacgacac aagcacaagc aagagtcaag
    14161 gacgatcgat gggaagatcg ggcggagttc gtcggtagga cgctgtttaa caaaacagtt
    14221 ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg aaattttgcg taacggtttt
    14281 cgctgtgatg ttctagctta tgatccttac aaatcagatt tatacatcga aagctttggt
    14341 gcaaaaaaag tagaacttca agaattactg gaacaatcag atatcatttg tttatgtgcg
    14401 aatttgacag aagagaacta tcacatgatt tctgataaag aagtcgatca gatgaaagaa
    14461 aatgtttatc tatctaatag tgcaagaggc gctctagttg atgaagaagc gatgattaat
    14521 ggtctgaaaa gcggaaagat cgcaggatat gccacagatg ttttagaaga agaaccggga
    14581 cgtcaagatc atccgtattt agcgtttgaa caagtagtga ttacgccaca tatatcggcc
    14641 tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg tcagagatgt cgaacagatc
    14701 agtcagcacc ttcttcctga acgttctgtc cagacaaaga gcaactatat aaaaggatga
    14761 tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc tcaattttat ttatatgaag
    14821 aaggtggtat ttcaaaagtt tctgatctct tgaaatcata cggcgcgaaa agagtactgg
    14881 tcacccacgg aacggtatca tgggaaaagg cgctacctaa attagtattt ttgaatgacg
    14941 aaacgattca atttttttat catcgttatt ctggagaatg tagttatgct gaagccagac
    15001 gaatagctac aatcatcaaa aaaatgaaat cgatttcgta gttggcgttg gcggaggaaa
    15061 actgaccgat ctagtgggtt atagtgccaa tcttgcaaga atcgatttcg gagtcatccc
    15121 tactttagct agtaattgtg ctccatggac acctcttgct gtcatgtata aggagaatgg
    15181 acaagcagaa gggaaaacag aacactttta cagacaagct gcttttttta taacagatcc
    15241 ccaattagtg attgattccc ctgttccata tttcattgcc gggttagcag atacactagc
    15301 aaaatggtat gaatctgagc tcatcttaga acaagatttt ttgcaagatg aatcattttt
    15361 gaagctagca caagatactg cgaagatctg caaagaagag attttgaatc attctgctaa
    15421 agcaatccaa gatatggcac aaagaaaact gacatcggag ttcaaacagc tttcagagat
    15481 tatctttgct gttgctggtt tagttggagg attaggagat aaatacgcaa gaaatgcggc
    15541 agcacatgct atgcatgacg ctatcagtaa atatattccg gaaagccatc gttttctaca
    15601 tggagaaaaa gtagcgtatg ggattttcta tcaactggca ctagaaggtc gctgggaaaa
    15661 aatagacgag ttatatcctt tgtatcggga attagaactg ccggtttctc tagaacaaat
    15721 gggattattt ccgaaagata aacagataat agataaaatg gctgaattta ttgattcgaa
    15781 agagaaagtg catttgattc ctatagaggt aacacagaaa tcactgatac agtcaatgat
    15841 ggaactggaa ggttatatca gaaagatctg aaggaggagg acacatggaa acattaagtg
    15901 tagtacaaag tttgttgatt gctttatggg tagccgcggt tatgtcccgc tggttaggtg
    15961 gaggagccac gttgacctta cgtttttctc ctttgatgac tggattagtc gtcgggttga
    16021 tcatggggga agttgcacaa gcgatgattg ttacagccgc tttgcaaatg atttatatgg
    16081 gggttttttc tccaggagga tcaatgccag ctgaaccatc tattgcagca gctatcgcag
    16141 taccagtcgc attattaggg gatctgtcgc cagaagcagc gattgccgtt gcggtgccag
    16201 tcggattgct cggaagttac ttgtatcagt ttcgtttttt catcaatact tttttaggta
    16261 aatatacaga caaagctgta gaagatttga atacaaaagc tatggcccga tcaattattc
    16321 tttatccaac ggttgcctca tttttattat tcgttccgct tgttttcatt gctttatatt
    16381 taggggcgcc attgatcgct gatgtaatca aagctttaga gggaacagtc gttatccaca
    16441 ttcttgaagt agtaggtgga gggttagcgg caatcggtat cgcgacaact gtatacgtta
    16501 tcggtcgaaa agattatctg gtctttttct tccttgctta ttttatgagt gttgttttga
    16561 aatctttaga tattacgatg gttacttatg ccatttttgg gattattatc gctttgatct
    16621 ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac aagcaataac aattcagcat
    16681 cttttgatga cgaagatgac tatgatgacg gattttaatt taggaggaat gggaaatggc
    16741 tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag atgtaacaaa
    16801 agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac gttacttggc
    16861 gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag atgaagactc
    16921 tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa gctggggtgg
    16981 cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag aagagtatga
    17041 agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg gattgatggg
    17101 ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata tttttatcgc
    17161 aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc cttttatctg
    17221 ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt tcactatggg
    17281 ccgtaatgct acaggcctaa tgcaaaacac tggtgttcag acagcgattg aaatgctatc
    17341 agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag tagaatcttc
    17401 attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg atcaaatcgt
    17461 gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata cgaaaaaagg
    17521 attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc tagcaggaat
    17581 cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt tagcgcgtgt
    17641 ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa gtggagtgaa
    17701 ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag atctttacaa
    17761 aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga aagctaaatt
    17821 ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa aaacagtcca
    17881 aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata ttggagggat
    17941 tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt taaataaatc
    18001 agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata tttattttca
    18061 agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt ttgatttgtc
    18121 ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga acgagctgtt
    18181 tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa aaaagagtaa
    18241 acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag atgtgacagt
    18301 cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag atatcgaaaa
    18361 agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag gaagttattt
    18421 catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat tgtccttcat
    18481 tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc ctcatcacgt
    18541 attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga gctacttttt
    18601 cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc gaaatacttc
    18661 atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg tagcgtatgc
    18721 gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat cgggtatgaa
    18781 aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc tacagttttc
    18841 gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt tgaaagaaaa
    18901 aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct atttgaccaa
    18961 aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta ttgctctttt
    19021 tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa tcatgatcgt
    19081 tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg tcgggacatc
    19141 gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat tcggagagaa
    19201 ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat ttgttgatct
    19261 aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga ctgaagaaaa
    19321 gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag aagcaatcaa
    19381 tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca aacaaggaaa
    19441 agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg aggacgattt
    19501 ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa aaaggggatt
    19561 cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt ggaactttgc
    19621 tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg aaagcatctg
    19681 ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac gatgcaatca
    19741 aggcagggac agatgaacga gattactata ttgataacta tatacgaaca atcaaaaact
    19801 tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt ggatgggcga
    19861 aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac gatcagaaaa
    19921 tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag tcaaagggat
    19981 tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg gaaaaactgt
    20041 atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta gaaaaagtga
    20101 ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat ccgccatggg
    20161 aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa attctaaatg
    20221 cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg gcaaatccgg
    20281 aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt gtccacttca
    20341 gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc tctacagaag
    20401 gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc gacggtccta
    20461 tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga tatggcctgt
    20521 atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata agtaaggaaa
    20581 aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat ggatggcctt
    20641 ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca aaagtatgat
    20701 tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat ggcgataaga
    20761 gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg agaagcaatc
    20821 aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa aaaaggagca
    20881 gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc ttcgtctaat
    20941 acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt gtttgatcaa
    21001 atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt tttgaaagct
    21061 tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc gattgcaggg
    21121 atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca tttgataggg
    21181 ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata tgaatccaat
    21241 aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga aagtaaaggg
    21301 ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc ctgcacgact
    21361 gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt atttgtagtg
    21421 aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat gcgtttaaag
    21481 agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt ttttaattct
    21541 tgcactgctt gttcgatcgt aacacctgtc gctacatgat tggtattttc tttgtcaaaa
    21601 acgacaaata gattcaaatc tgtatccaag gttactcgat attgtatatc tttgttatag
    21661 aatgtcatag ccattctcct ttctttaaat acttgctgaa aggcaacgaa cgcgttgata
    21721 acgaaattcc atttataagt ataccaccaa ttgaaaggtt ttcatagtta agaaatttta
    21781 aagtcaaaag ttgcagataa aagcaaataa acaagaaaac aaaaagtgaa tcaatcgcgg
    21841 ttattcaact ttttcttcga ttcgaagaca atagaagaca atgaatttta tatttcattg
    21901 cattatcctt gtgttattag aaaaagcatg atatattaaa tgagtaatct attttgaaac
    21961 gtaatttgag cgatatatct acatagataa aactcctttt gcctatcaaa tatttattgc
    22021 aacgaaaaaa cgtacattga tacgtatcag gaggaattta tttatgaata acggtacagt
    22081 aaaatggttc aacgcagaca aaggttttgg ctttatcact ggtgaagatg gaaatgatgt
    22141 atttgcacat ttttcagcta tccaaggtga cggcttcaaa actttagaag aaggccaagc
    22201 agtgtcttac gatgttgaag atggtcaacg tggccctcaa gcaacaaaca ttgttaaagc
    22261 ttaataaaaa ttgactttta accgtctttt cgaaagaaaa gacggttttt ttgtacgaaa
    22321 aaattcattg gtcgttgaat gggctgaata gtagtgtata aaacaatttt gtggagcgtg
    22381 aagcttttat ggtagaggaa aatacgaata aagtgatgtt gataaaaaga ttcctatctt
    22441 gaatatgaat cgagatgtct tgaaaatgaa tgagtttgac caatcattat cctatcgaaa
    22501 tttacagttt cgttcgattg gtctgtcaat taatgaaaaa gtaaaaaaga atatgttcta
    22561 ggaagagggc ggcacatcta aatttttaag taacggacag ttcaaatatc aagcattgaa
    22621 agaggctatc ctactgtttg aaggaatacg aatatataaa aacgacaaag aggaaaaagt
    22681 agttcattaa atcccttcaa gtgatgaaag aatgagatct aataaaacct gatctttcat
    22741 ctgttttttt aataacgtaa taattttttt attttttgtg ctttcgccgt tattgtagag
    22801 tgatttagca ttcttatttt taaaaataac tgtgttatat attaaaaaag gcataatagt
    22861 tataagcttt tttaaagaat atttagaaat tattaatttt cgtctgaaaa caaaaaaaga
    22921 aagcgttatt attttagtct attttcaggg ggggaacctt atgataaaaa aactattttt
    22981 actatcaata ttaacgctag caatggcagg ttgttctgac tctggcttag caactgaact
    23041 gatcacaaaa tcaactgaag ccacgacaga ggagttaaaa tgtggaaacg atcacagtga
    23101 ctacagaggc ttaaatcgac gatgcatggg aatattaggc agaagcaatt gtaagcatcg
    23161 atgtagtaat cgaagaaggt gtagaagaag caacagaaaa atcaaaagaa agatcaaaag
    23221 aagcaatctg tgctgtgcat cgtatacaga cgtcgaagat gcggtacttt taaaccacgt
    23281 caggagatgt tcatttatgt ctagggaagt tggcgatgaa ccaaaactag agtacgcttt
    23341 tagttttgca cgtgaggatg aagataaccc taaaacttac gacattttag cttgatctaa
    23401 gatggttaaa gctttttaat gaagtaagag gagatagaag gcttttctag ttatattagg
    23461 taagataaat tcctttttgc tccaaatttg ctaaacattc tgctagataa acttcatcgt
    23521 gttccggata aatcggcacg ttgcgctcta cagtaggtaa atcaaaaaat gcttcgcatg
    23581 atttgccacg atacatagga tttttccact ctggtgctgg gctgtaacca cgtttttcca
    23641 tttcatccat gacaagctga tgatattgga ataatctata aggagaatag tgaaaaacat
    23701 aatccacagt agcatgtttc tttccccagc catttcctct taatgcacag cattcccgat
    23761 gttgtcctaa aagctgttga cgaggaagct ttgaaatcaa tttttcatgc cataatcgca
    23821 tagaaatgtc tcctttatat atagattgtt aaccttagac gttaaatgaa aaaaccagca
    23881 ccaaggctgg aaaaaatcac ttcagtttgc ttgctgtttc tgagcgacca attaggtaat
    23941 caacggaaat atcgtaaaag tcagcgatat agattaattc aatgatgctt ggaatttctt
    24001 ctccttcttc gtacttacga tatttgaata aaggaatact taacgcgcta gaaacagcta
    24061 cttgagataa agatcggcca gttcttaaga aattcagacg acaacgtaaa gtatccagta
    24121 aaatagcttc ttcgatactc atttaatcac ctttcattat agtagaatag ttataatgac
    24181 tatagaaagc tacacatgca atcaatagta ctcaatgttt tttatttaaa cgtatcaaat
    24241 aaagaatgac gatcaataaa gacaaaacca gtcctgataa ttcttctata aaaacactat
    24301 cgggttcaaa gtagttgtaa ttaaaaactt tccacataaa gtagatagcc ggaagagtca
    24361 aaatagctaa ataaaaccgt tctttgttcc aattcataag ataaacaata cttgcgacca
    24421 gtgcgaccgc aggcacccaa aacaaaactc tcaccaacgt aatcatgtaa cggactcctc
    24481 aacgattcat ataataaaag ataacatgtt attgcataca tcacaaatga aatgctagga
    24541 aaataaaaga agaatagatc aatgaaaaat gaaaaagcag aacagttttc tgctgataag
    24601 caggaactgt tccgctgaat gtgtcttatc tatcgagaaa aaatcaatgg attgatatct
    24661 aagtaattca atacatataa aaagaggacg atcgcattca ctaaaaagga aagaatgatg
    24721 atcccatagc gaatggaaac atatttaaca aatacttttg tttgaatacg ggcatatctt
    24781 tttcctttat agctgagcat catgacaaga agcaaaaggg taatcacacc ttgaaaaatc
    24841 attccaataa acagaattcc tgaggtttga taatttaatt ggagaaaata agctgctgcc
    24901 gcaactaaat cgaataaaat cgcaataaat ggcaaaataa tcactcctaa cattgagaat
    24961 aaataaaaga ataacatttt ttctaaaata agcaaataaa aattaaagta acaaaatagt
    25021 tatgacacaa gtaaaagaaa taagaataac aatattattt tacttatatt ttgaaacttg
    25081 tgagagtttg tcattcgtgc tatagttgaa aagtaacaaa aataaatttt atttatgatg
    25141 tacctttagc tcagttggtt agagcagacg gctcataacc gtccggtcgt aggttcgagt
    25201 cctacaaggt acataagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
    25261 aagtaaaaac agcttcttat gtttttactt ggctgttctt attactgcag atgcaagctt
    25321 ttgaataccg tttaaggaag aggttgtgaa atcagcgttt tgacctgagt attagcttaa
    25381 caaacggaaa aatagttcct catattttgc cgtttgttaa gctaataccg agggtcagct
    25441 gattgaacac catttaagaa agaggtcgtg agcctgccgt ttcactctgt gtcataaaaa
    25501 agccaatcta ctttgataga aaaagcacgt aggactaaaa cagttctgcg tgcttttttt
    25561 attgtgtgtt aaatatcgta aatgaagata gatattttta tgattcgacg atagagacgt
    25621 tgaaatcttt caacagctct aaagcggatt ctccgtgttt tctactggag actaacattg
    25681 gatcaacaaa aaagtctgct tcaggaaaag cactctgcag gcctatcaga ttagagagta
    25741 cacacaagtt tgtttcaatc ccgactactt cgatctcttt ttgttcttct ttgctttcaa
    25801 ataaagtttc ctggatttca gctaaagttt caggtggaat cgtaaagtaa tactttttaa
    25861 tcactcgttc attttcttgt ggagaaagaa gagggatcaa ttgcaaatct tctcgttctt
    25921 cttctttgtc cttcagttca actggtatat cccgtgtgaa gagaatatat tcattatttt
    25981 ggcgtgcttt agctaatctt tgagcaatac gttctgccaa ttgatctgac tctggaatat
    26041 aaaattcgct gtttggatca agaatatgat tttgcatatc aataataact aacattttct
    26101 ttcctcctac attcatatcg tcattttatt ctttttaata gaagtttttt aaaatataag
    26161 caacaccagc ttcttcattc gtcagtgtta cttggtttgc aatttctttt acttgtcgct
    26221 gtgcattccc catcgcaata ctcaacccgc tgtaattcaa catagcaatg tcgttttctt
    26281 gatcgccaaa agccatgatg tcactcgatt cgattccaag gtaatccgcc agaaaaacaa
    26341 gtgaatgagc tttagtgata cctgtaggcg tgatttctaa gaaatgcgga tcagagaata
    26401 ctgattggat accatctgct tgcagatctc tttgtagctt ctgtagtttt tcttcactct
    26461 tatctgttaa tgctaattta agatagctaa gagaaggatc ttccaacata tttaaaattt
    26521 gatcaaaaga atggttctgt aaattgaaat gttcataata agggtcatct ttgactagat
    26581 ttgattcatc gaatgtcagc tgatcatctt gggtttctcg gctagcaatg atggatattt
    26641 tcgcttcttg agcatagaag aaggcttttc tcagtgtatc gctatctatt tttgaacgtc
    26701 tgagaacttt cgccattttt ccatccttca tttcagcaat cagtgaacca ttggaagaaa
    26761 tcaaatagcc accgattcct aattcggaaa aaatatcttt agcagaaatg ctgttccttc
    26821 cggtagcgac ggttacgatt ccgccatttt catcaaattt ccgaagtgct tggatatttt
    26881 cttctggtat ctttccattt cgatcaagca aggtaccgtc taaatcaatc gctgctagtt
    26941 tcattttatc ttcctacttt ctttttacat atctattttc ctgttacctt aagattaaat
    27001 gagaatttaa aaaaatgaaa ctaacttgct ttgtcattat gaattttttc aaaaaacatt
    27061 cttaagaaaa aggtggctat atatagtagt ttttggtcaa tacctttgaa taaaaagcca
    27121 tgaaaaacga atagttagcg cttaccgatg cgttttgtga taaaaaaatt ttaaaatatt
    27181 caatgaaaac aaagcatata ttttgcttta aaaccaaatg aggaatattc tagatgtaga
    27241 acaggttaga aaaagattag aaaaaggagt gattttgatg gagaagagat acggcgtagt
    27301 tcctgtggta actgcttcag acgaaaatta tgctccttac ttgagcgtga tgatcgcaac
    27361 tgcattagaa aattgcaata aaacaagacg cataaaattt tatgtgattg acgatggtct
    27421 atcagaatat agtaaagaag gattggaaga aacggtaaat aaatattcaa gtaatgcaag
    27481 tatccaattc ctgacagtgg aaaaagatat ctacgaagac ttcctagtca gtgaccatat
    27541 cacaactacc gcttacttaa gaatttcttt accaaactta ttagctaaag aggattataa
    27601 gaaagtcctt tacttagatt cagatgtgtt agtactagac gatatcgtaa aactatatga
    27661 tgagccgtta aatggaaaaa caatcggcgc tattatcgat ccaggccaag tgaaagcttt
    27721 ggaaagatta ggaatcgatt ccgatgactt gtacttcaat tcaggagtga tggtgattga
    27781 cattgatcaa tggaataaaa aagaaattac agaaaaaact atccattacc tcagtgaaaa
    27841 tggcgatcga atcatctatc acgaccaaga tgctttgaat gctgtacttt atgaagattg
    27901 ggaacaactt catccaaaat ggaacatgca gacttcgctg atttttgaac gtcatccagc
    27961 accaaatgaa aaatatgaac gtcagtataa agaaggaaat gaaaaacctt cgatcgttca
    28021 ctttacagga catgataaac cttggaatac gttgaaagat catccgtata ccaatttata
    28081 cttaaaaaaa ttagcacaca gtactctaac gaaagtaggc gagatcaatg aataaaaaag
    28141 aaatagcagt agtcgcaagt tgtaacacaa aattcgtacc acatttagct gcattatttg
    28201 tctcagtatt agataattgc aacccgtcta aatttgttcg gttctatgtg attgacgatg
    28261 atatcgattt tgaaagtaaa cagcttttac gcttctcagt gaaaaacgca cgaatgaact
    28321 cagatgtgga attcttgaaa atcaataaag aattctttac aaatgtggta atcagcgatc
    28381 gtattccaga aacagcttat tatcgtattg cgattccgga attgttccgc ggcacagaag
    28441 ttgaacgtat cttatatatg gattgcgaca tgatcgcttt acaagatatc tctaaattat
    28501 ggcgtcttga cttcggtgat tcaatcgtag cagctgttga agacgctggg ttccatcaac
    28561 gactggaaaa aatgaaaatt tcagctaaat caatgcgtta tttcaactca ggtttgatgc
    28621 tgatcaatgt gaaaaaatgg ttagatgaaa atattacgca aaaagtatta gatttcatcg
    28681 aacataatcc agaaaaatta cgattccatg accaagatgc attaaatgct atcttacatg
    28741 accgttggtt accacttcat ccgcgttgga atgcacaagg ctatatcatg gcaaaagcaa
    28801 aaaaacatcc aacagcagca ggtgaacgtg aatacgaaga aactcgcaac aatccttaca
    28861 ttatccattt ttcaggacat gtgaaaccgt ggagcaagga ttttgaaggg ccaacgaaga
    28921 aatattacga aaaatatgca gggatgacgg ctttccgttg tgtagctaaa ttccctaaat
    28981 atccaaaata tgcaaaagtt caaccaaaaa cagatgtagt tgttaaataa tagaagacca
    29041 caactgaaga gggggagtag gaatggaaat tacaatgtct aaaaatgcag tagagacgtt
    29101 aattgaaaag gttggggaaa atacaaaaat cgcactcgcg cttatcaatg attccgatcc
    29161 atttctaagg gacaaaggtg cttttgcaaa aggcagcttt tttcaaatca ttccttttgt
    29221 ttcggaattt ggagaatatg cgactaaaat cgagcatcca ttattggaca tctatacatc
    29281 taaattagag caaaattatt tcggtaaacg attgaacatg gacttcaaca aacagcttga
    29341 cagcttttca ttagaaaatg aaatcgcagt actcgattat aatatcaaat taaagaactg
    29401 cttcttcagc taatagtttc gagaaagtcc aaaaaggagg tatacattga gatactactt
    29461 tgtggatgaa gaaaagaatg taatagaaac agatgaaaaa aaatataatt ggctcgtact
    29521 tgatagtgca aagcccgaag agattgagca agcaatcgaa gaattcgagc ttcctgatga
    29581 tattttcgta ggaaccgaat atccggaaga agtttctcgg atggagcgcc tttatgagac
    29641 gaaactagag catccatttt ctttggtagt gattaatcta gatcagtcag ataatcgtat
    29701 cgaaaaaaaa ttaacgccaa tatcttttgt actttccgat aatctcttga ttacttgtat
    29761 cgatagaaaa accgaatttg tggatcggct gctgacaaag catggaaatc atttaaactc
    29821 gtttgaaaag atcatcacgt atacattatt agatatttac acccattacg tgaaagaact
    29881 aagagagatg aaaaagcgaa ttgacgcttt ggataaagca gctcgtaaaa caacggaaaa
    29941 tgaagaactg tataaacagg cagatcttga aagagacatc gtatatatcg atcatacctt
    30001 aagagatcaa cgggaaacaa tggatcaatt atggaattct gaaactttca tcaaacgttt
    30061 agacgatgaa cagctactct atgatgtcca tttgagacag cgacaaacag aaaaaatgat
    30121 cgagatctat cgagatttat tagagagtat tggtgatcta ttcaacggga tgatggacaa
    30181 taatctaaat catatcatga aatatctaga ttcagctgca ttaatcattt ccgttccggc
    30241 gttgttcgca gggatttggg gaatgaatac aggaggatta ccgggtaaaa gttctgctct
    30301 aggctttata ctcgtagtct ttggctcttt gatagcagca gtagttttag gttaccattt
    30361 ataccggaaa gattatacaa attaaagaat ctatttaaaa caggtatcaa acaaagaaat
    30421 ttgttttggc aatacaattt aaaaactagg aggaatacag caatgacaga accaaaatta
    30481 atcgacccgc gaaacttgta ccatacggag aaatttccta aacaagatca ggatacacca
    30541 gctttacagc agaatatgat tcctgttcct gattgtggag aagaatccta tgaaggcaat
    30601 aatcaactag aaaaccgccg tgtactaatc actggtggag attcagggat cggtcgtgca
    30661 gcagcgattg catttgctag agaaggggca gatatcgctc ttcaattctt cccaggagaa
    30721 gaaaaagatg cagaggaagt agcaaaatac gtgaaagatg caggacgtaa gattgtctta
    30781 ctaccttttg atcttcgtga cgaacaagca cctaaagaaa tcatagataa agccgtgagt
    30841 gaacttggcg ggctagatac gatggtacta aacgcaggac agcaaatttc ttgtcagtct
    30901 attgctgagt taccacttga gcaagtcaaa gacacattta tgataaacat catcgctatg
    30961 tttgctttag tgaaagaagc tgttccgcat atcccagcag gaggagcaat cgtaacaaca
    31021 acttctgttc aagcattcaa tccaagcgaa catttattag attacgcagc aacaaaagct
    31081 tcaatcgcta actttacgat cggtttagca aaacagcttg cacctaaagg aatccgtgta
    31141 aatggtgtag cacctggtcc aatttggaca ccattacaac tagacgaagg acaaccttct
    31201 gattcgatcc ctgaatttgg tcagcaaagt ttactagaac gtgcaggtca gccaggagaa
    31261 ttagcaccag tttatgtttt cttagcatcg aataaagcaa gttatgttac agcccaaatt
    31321 tacggagtaa ctggtggaga agcgatcaac ttataagaag ttgatcgttt cacccctatg
    31381 aggaggtgcg aaaatgaata aaggtgtaaa aacgatcgga gtgatcggaa cattactttt
    31441 gctatctgtg cttttgtttg cgatactatt aagtgcaacc tatccattgc cttttcagct
    31501 agagaagttt cgattctttt ccatcactaa ttcatacgtg caacaatatg tattttggct
    31561 tgccgttgca tttgctattt tgacaattat cacgttactt gttttcctgt tttatccaaa
    31621 aacaatcgga aactttctac tgaaacatgg tgatggggag ttgacgttgg ataaaaaagc
    31681 aattgaagga atggttcgtt ctcacttgca tgaagatgaa ttcatccatt caccaaaagt
    31741 aaatgtcaaa gcaacgaaaa acaagatcgc cgtcaatgta aaaggggagt tgaaacgaac
    31801 ttcagcactc attggtaaaa caggaacatt gatgaaagaa atcgaaaatg aagtacaaca
    31861 catattggga acaaaagagc cagtgaaagt atcggtgaaa tacacaggct ttgaagaacc
    31921 agctaaacga agcaatgacc gcaaacgagt agaatagggg gggaccaaaa atgaaagaac
    31981 tattttcgac atacaagctc cctatcatct ttggggtact tggattgata ttagccgttt
    32041 tatggatcac cgtgggcttt ttcaagacct tattgatctt gatcatggca gcgatcggcg
    32101 tcgctatcgg tttttatctg aaacaaacga aaatcttaga tcactatttt aaatcttagg
    32161 aggaaacatc catgaataac aataacaaaa ataataacaa taaaatgaac aaccaaaaac
    32221 cagtgtctgc acatccagac ccaacgacac caaaccaatc aaatggtgtg aacgatgaaa
    32281 agaacaaaac agcaccagta tctgcacatc cagatccagt agtccctaac gttcaacaag
    32341 gagtagaaga gaagaaacat gatgcagaaa agcatgcacc tcatcatcca ggaactccag
    32401 aatctaaagt tccagaacaa catgatgcaa tcgatccttc taaacctgtg gaagagcaaa
    32461 aacatccttc tgaccatgcg aaagcacaag aaaaacttag ttctgaccac acaaacggac
    32521 aaggaaaact tggttctgat catacaaata accaaggaaa gcatgattct gaacaggaag
    32581 attcaatgcg cggtgagctg aattatgaag ataaagttgt gcaaaaaatc atcggaatcg
    32641 caattgaaca agtagacggt ttattatctg caaacggtgg tttcttctct aatgtggcag
    32701 gaaaacttgt gaatacagat aatgtaacgg ctgggatcga aacagaagtc ggtaaaaaac
    32761 aagtagcagt tgatatggat gtcattgtgg aatatggcaa agatatcgaa aaaatctttg
    32821 aagaaatgca agaagtaatc ggcaaagaag taaaaaatat gacacattta gaagtgatcg
    32881 aagtcaacgc taacgtagtg gacatcaaaa caaaagaaga atttgaaaaa gatcaagaaa
    32941 cggtgcaaga caaagtaact gacgcagcga aaaaaaccgg tgaatttgct tcgaatcaaa
    33001 cagataaagt aaaatcagca gctggaagcg gcgcacaaaa agtaaaagaa aatacagaac
    33061 cacgggttca gtaataagga agtaaaacat taggaggaac gaaacatggg atttatttgg
    33121 tcacttatcg tcggaggaat tatcggagca attgcaggag caatcacgaa taaaggttct
    33181 tcgatgggga ttattgcaaa tgtcgtagca ggtttagttg gatcagcact tggtcaagca
    33241 ttattaggtt cttggggacc aagtattgca ggaatggcaa tcgtgccatc attgattggt
    33301 gccatcattt tagtactaat cgtatcattc tttgctcgaa aactgtaaaa agacttttaa
    33361 aaagaggtcg tgaaaaagct gttcttcatc aagtaataag aacagccaaa caaaaatagc
    33421 ttctcatatt tttcatttgg ttgggcatat tatcgaagat gcaagctttt gaacactgtt
    33481 tatacggaat aagaggctgt gacaagactt ttgtcacagc ctcttattta tgcgggcaaa
    33541 ttcccaatta gatttttaaa agtttttcct taaatgtgtc tttattgata cagagaagct
    33601 tctttaataa aacaatgcct ccctaaattt tcttgagata ggaaaggtga acatacaaaa
    33661 taatacgacc actttgaaaa cccagatgat ccacaaatgg atcgtatgat actgatgaag
    33721 taaaaagcaa tggatcagaa actcaaagag attgaaaaag acaaggaaga aataatatct
    33781 cttttttact cttgtctgtt ttagccaata atagctcgta aagtaatcta gacaaacaaa
    33841 tagaagtaaa caaagtttcg taagagcagc aatcgtatca tgttgctctg ctagacgatt
    33901 gacgagcagg aaaaatgttg gtaatggaat atagatcacg agtaatgaaa gaaaaaagta
    33961 aacaataaat ggcatactat tcctcctaat tgtgtgagtt cgccctcatt ttaaaataac
    34021 gatatttgtt tgtgaagctt tttcgtgtcg taacaaatgt tatctaatgt atttttaaat
    34081 aaataatcat tattatcaaa ataat
//
LOCUS       DAIGSZ010000030        33264 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.030, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000030 DAIGSZ010000000
VERSION     DAIGSZ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.030"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(42..230)
                     /locus_tag="NOB31_001454"
     CDS             complement(42..230)
                     /locus_tag="NOB31_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HCI0973667.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            500..862
                     /locus_tag="NOB31_001455"
     CDS             500..862
                     /locus_tag="NOB31_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI0973668.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            914..2596
                     /locus_tag="NOB31_001456"
     CDS             914..2596
                     /locus_tag="NOB31_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HCI0973669.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2713..4749
                     /gene="recG"
                     /locus_tag="NOB31_001457"
     CDS             2713..4749
                     /gene="recG"
                     /locus_tag="NOB31_001457"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HCI0973670.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4798..5799
                     /gene="plsX"
                     /locus_tag="NOB31_001458"
     CDS             4798..5799
                     /gene="plsX"
                     /locus_tag="NOB31_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HCI0973671.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5921..6163
                     /gene="acpP"
                     /locus_tag="NOB31_001459"
     CDS             5921..6163
                     /gene="acpP"
                     /locus_tag="NOB31_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCI0973672.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6431..7435
                     /locus_tag="NOB31_001460"
     CDS             6431..7435
                     /locus_tag="NOB31_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0973673.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7436..8380
                     /locus_tag="NOB31_001461"
     CDS             7436..8380
                     /locus_tag="NOB31_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0973674.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8380..9342
                     /locus_tag="NOB31_001462"
     CDS             8380..9342
                     /locus_tag="NOB31_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973675.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9369..10283
                     /locus_tag="NOB31_001463"
     CDS             9369..10283
                     /locus_tag="NOB31_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973676.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10309..12090
                     /locus_tag="NOB31_001464"
     CDS             10309..12090
                     /locus_tag="NOB31_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0973677.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12438..13124
                     /locus_tag="NOB31_001465"
     CDS             12438..13124
                     /locus_tag="NOB31_001465"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HCI0973678.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13144..16725
                     /gene="smc"
                     /locus_tag="NOB31_001466"
     CDS             13144..16725
                     /gene="smc"
                     /locus_tag="NOB31_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HCI0973679.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16734..17543
                     /locus_tag="NOB31_001467"
     CDS             16734..17543
                     /locus_tag="NOB31_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0973680.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17554..18552
                     /gene="ftsY"
                     /locus_tag="NOB31_001468"
     CDS             17554..18552
                     /gene="ftsY"
                     /locus_tag="NOB31_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HCI0973681.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18739..21006
                     /gene="gshAB"
                     /locus_tag="NOB31_001469"
     CDS             18739..21006
                     /gene="gshAB"
                     /locus_tag="NOB31_001469"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HCI0973682.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21095..21547)
                     /locus_tag="NOB31_001470"
     CDS             complement(21095..21547)
                     /locus_tag="NOB31_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HCI0973683.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21697..22647
                     /locus_tag="NOB31_001471"
     CDS             21697..22647
                     /locus_tag="NOB31_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCI0973684.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22640..23599
                     /locus_tag="NOB31_001472"
     CDS             22640..23599
                     /locus_tag="NOB31_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCI0973685.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23596..24351
                     /locus_tag="NOB31_001473"
     CDS             23596..24351
                     /locus_tag="NOB31_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0973686.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24374..25327
                     /locus_tag="NOB31_001474"
     CDS             24374..25327
                     /locus_tag="NOB31_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0973687.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25971..26267)
                     /locus_tag="NOB31_001475"
     CDS             complement(25971..26267)
                     /locus_tag="NOB31_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HCI0973688.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26622..26978
                     /locus_tag="NOB31_001476"
     CDS             26622..26978
                     /locus_tag="NOB31_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI0973689.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26988..27887
                     /locus_tag="NOB31_001477"
     CDS             26988..27887
                     /locus_tag="NOB31_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HCI0973690.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28404..29135
                     /locus_tag="NOB31_001478"
     CDS             28404..29135
                     /locus_tag="NOB31_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI0973691.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29280..31307
                     /locus_tag="NOB31_001479"
     CDS             29280..31307
                     /locus_tag="NOB31_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HCI0973692.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31415..32512
                     /locus_tag="NOB31_001480"
     CDS             31415..32512
                     /locus_tag="NOB31_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCI0973693.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32819..>33264
                     /locus_tag="NOB31_001481"
     CDS             32819..>33264
                     /locus_tag="NOB31_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973694.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11139 a         5762 c         7123 g         9240 t
ORIGIN      
        1 aaaaaaccgt tcactatctg aacggtccaa gtatcattca attaaacgcg ttcaactttt
       61 cctgatttca aagcacgagt tgacacccaa acttttttag gttttccgtc gaccataacg
      121 cgaacttttt gtaagttagg tttaacagta cgttttgttg agttcatagc gtgtgaacgg
      181 ttgtttccac tttttgtctt gcgacctgta aagtaacaaa cttttgccat ggtaatttcc
      241 tcctttgcct tgatttggag caatagaata attcagctca taccagacta acatatcata
      301 tagaatggaa atttgcaagt acattttcat agatacaatt gacaattgag aagaataatt
      361 gtaaattaaa caaggttata cctgaaattt tgcaaggttt ttgagtactt tgggtaactg
      421 ccttttattt caagttgcgc tatgataaaa tatgatagaa gaaaaatggg agttttttac
      481 ccgttaagga ggctcattca tggctgtaaa aattcaaacg tcagctggaa ccattgaaat
      541 taccaatgat gtaattgcaa cagttgttgg tggcgccgcg acagatgtgt tcggtgttgt
      601 aggaatggcc agcaaaaatc aaattaaaga taatattact gagattttgc gtaaagaaaa
      661 ttactcaaga ggagtagttg tccgccaaga agataatggt attgctgtag atgtttatac
      721 gattatcagc tatggtacga aaatctctga agtttcccgc aacgtccaag aaaaagtgaa
      781 atacaatcta gaggcattat taggcgtaac tgccaattca gttaatgtct ttgtacaagg
      841 tgttcgtgta ctgccagact aggcaggaga ctggctggta actcagcagt cgatctgaag
      901 gaggattatc taggtgagtg taacagaaat aagtgcaagc cagttccagg aaatggtcca
      961 ggcaggtgcg aatcgtctgc aagtaaatgc agaatacgtc aattcattaa atgtattccc
     1021 tgtgccagat ggcgatacgg gaacaaatat gaatctatct atgactagtg gagctaaggc
     1081 agtagtagat tcaacctcag aaaaagtagg agaattagca gcaatgcttt caaaaggatt
     1141 gctgatgggt gcgcgcggaa attccggcgt tattttgtct caattgtttc gtggattttc
     1201 taagcaaatt ccagatgttg tctcattaaa tgcttccgat cttgctgcag ccttcactca
     1261 tggagttgaa actgcgtata aagcagtaat gaaaccagta gaaggaacga ttttgacagt
     1321 agctagagaa gcagcgaaag ctggagaaaa gaaagcaaaa agtactgatg atgtcgttga
     1381 agtaatgaca gctgttgtaa aaggggcaaa gcgtgcttta gctaaaactc cagacttgct
     1441 tccagtccta aaagaagtcg gtgtcgtaga cagtggaggg caaggactgc tgtttgttta
     1501 tgagggcttt ttaagtgcat tgaatggaga attccaagcg gatgaaacat atgaaccttc
     1561 tccagcagaa atggatgata tggtcaatgc agaacatcat cgcagtgtcc aaggtcaaat
     1621 ggcgacagaa gatatccatt ttggttactg tacagaaatc atggtaaaaa tcggagaagg
     1681 acctacagtc gatagtacat tcgattacga agaattccgt aactatttag atggtatagg
     1741 agattcttta cttgtggtca atgatgacga gatcatcaaa gtccacgtgc atacagaaaa
     1801 cccaggagaa gtcttgaatt atggacaaaa attcggttca ttagtcaaaa tcaaagtcga
     1861 caacatgcgc ttgcagcatg agacgatttt ggaacacgat gaagaagtga acgagtttgc
     1921 gaaaaaagaa acaccacgta tcccgtatgg tatcgtagcg atcgctgctg gtaaaggcgt
     1981 ccaagagctg tttgaaagtt taggcgctaa ttatgttatc agtggtgggc aaacaatgaa
     2041 tccaagtacg gaagacattg ttaaagcgat tcaagaagta aacgcagata aagtgattgt
     2101 cttgccaaac aataagaaca tcttcatggc agctgatcaa gcagcagaag tagcagatat
     2161 cccagtagca gttgttcctt caagaacgat ttcccaagga ttgacagcta tgctttcatt
     2221 caatgatcaa gcttctttag aagaaaacaa agaaacgatg acagaaatgt tgtctagcgt
     2281 tgtgagcggt caagtcactc acgcgatcag agatacctca attgacggtg tagagatcaa
     2341 agaaggagac tttttgggca tgatcgatgg aaaaatcctg atctctaacc cagatatcac
     2401 agcaacagcg ttaagtacac tagaacaaat gatcaatgag gacacagaga tcgtaacgat
     2461 cttggcaggt gatgaaggaa cagttgaaca agcaaatgaa tttgctgaga aactaacaga
     2521 aaaacatcct gatttggaaa tcgagatcca ccaaggagat cagcctgtct atccttatct
     2581 attttctgct gaataatttc tgtgtcagaa tatctttcta acacagtatt cattcataaa
     2641 aggccttcgg ttagtgatca ggtatgatcg ctgaccaagt cctttttttg ttaagggagg
     2701 gaggaaaaat ttatgcgttc tttagatgat ccaatcacta tgctggcagg agtcggagaa
     2761 aaaagagcag ctagtcttgc cagcttgggc atccaaacga ttgaagactt actgacttat
     2821 tatcctttcc gctacgaaga tattcaggaa agaaatctaa acgagatcca agatcaagaa
     2881 aaggttactt tgaaaggaat cgtagtctcg cctcctgtga tgaatcgatt tggttataaa
     2941 aaaagccgat tgcaatttcg tatgatgcaa gaacatgatg tgttcaacgt ttcttttttt
     3001 aatcaacctt atctaaaaga aaaagtcatt ttatcggagg aaatcgccgt atacggtaaa
     3061 tgggatgcaa agcgtaaagc attgaacggg atgaagattt taggttctca aacaatggat
     3121 gacttttcgc cgatatatca cgtcaacaaa tcaattcgtc aaacgacatt agttgatcta
     3181 atcaaaaaag ggtttcaaga atacggcaca ttgattgaag aaaatctgcc aaacaacctt
     3241 gtggagaaat atcgactgct tgaccgagct tctgctgtaa gaagtatgca ttttccaaaa
     3301 gaccacgaag aaaaccatca agccaaacga cgtgtcgttt ttgaagagtt ctttttattt
     3361 caaatgcgtc ttcaaggatt gaaaaaagca gaaaaagcag aaacgaatgg tttggagatc
     3421 ctttatgatg tccaaaaatt gaaagaattt actcaaaagc taccttttga actgacaaat
     3481 gcacaaaaac gtgtaacgaa tgaaatctgt cgggatcttc gcagtccgca gcatatgcag
     3541 cgacttttgc agggagatgt aggtagcgga aaaacagtgg ttgccgcgat tgcgttatac
     3601 gctaccgtta cagcaggttt ccaaggtgcg ttgatggtgc ctacagaaat cttggcacaa
     3661 caacatatgg aaagcttgca acagctgttt gatcccaatg aagtaaccat cgcattgctt
     3721 acggggtcaa cgaaagcaaa agaacgtcgt gagctccttg aaaaactaga gcaaggggaa
     3781 attaacatcg tgatcggcac acatgcattg atccaagatg gagtcgaatt tcagaattta
     3841 ggtctagtta ttacggatga gcagcaccgt tttggcgtga accagcggaa agtacttcgt
     3901 gaaaaaggct ggcgaccaga tgtcttattt atgacagcga ctccgattcc tagaacatta
     3961 gctattacag catatggtga gatggatgta tctatcattg atgaacttcc agctggacgt
     4021 atcccgatcg aaacacgctg ggtaagaaca cctcaattgg acagtgtact ggattggacg
     4081 aaaaaagaac tggcaagagg acatcaaatg tatgtcatct gtccgctgat tgaagaatca
     4141 gaagcattag atgtaaaaaa tgcagtggaa atctatgaaa aacttcgtga actatttgca
     4201 ccaaaatatg aagttggctt gttacatggt aaaatgaaga atcaggaaaa agaagtaatc
     4261 atggaagcct tcaaagacaa ccagatgcag atattagttt cgactactgt aattgaagta
     4321 ggggtaaacg tgccgaacgc gaccgtcatg ctgatcatgg atgcggatcg atttggattg
     4381 gcacagctgc atcaacttcg tggacgtgtt ggacgcggaa gtgatgcttc ctactgtatc
     4441 ttagttgcta atcctaaaaa tgaactaggt gtggaacgga tgaaaatcat gacagagacc
     4501 accaatggtt ttgtactaag cgaaaaagat ctggaattac gtggtcctgg tgaagtattt
     4561 ggcttccgtc aatctggtct gcctcaattt gcgattgctg acttggtgac ggatggaaat
     4621 gttttggagg tagccagaga agaggctgca gccctttggc agataaagga ttggcagatg
     4681 cttcctgagt atcagccttt agcgcaaagc ctccaaatag aaaatcagga taatcgttat
     4741 ttcgattagc agactgtgct atactttata ctgatgacgg aaaaaggagt ggaaacaatg
     4801 aaaattgccg tagatgcaat gggcggagat cacgcacctc aagcaattgt agaaggcgtg
     4861 gctttagcgc agcaagattt tccagaagta gaattcttac tttacggaaa agaagcagaa
     4921 atcaagaaat acttaacaaa tgaaaaaaac atcacgatta tccatacaga cgaaaaaatc
     4981 aatagtgatg atgagccagt aaaagcaatt cgacgaaaaa agactgcatc aatggtcctt
     5041 gctgcacaag cagtgaaaaa cggtgaagca gatgctgtat tttcagcagg gaatacaggc
     5101 gcgctactag cagcagggtt gttcatcgta ggacgtatca aaaatatcga acgccctggc
     5161 ttgatgtcta ccttgccagt agtagggaaa gaaggtgccg gtttcgatat gctggatctt
     5221 ggcgctaacg cagaaaacaa accagaacat ttgttgcaat acggtatttt aggttctttt
     5281 tatgcacgta aagtccgagg tatcggacgt cctcgtgtcg cactcttaaa caacggaaca
     5341 gaagcaacaa aaggtagtga agtgacgaaa aaagcctatg aactccttca gaatgaaaca
     5401 agcttgaatt ttattggaaa cgtagaagct cgtgagctac tcaatggtgt ggctgatgta
     5461 gtggtcacag atggatttac aggcaacgct gttttgaaat ctattgaagg aacagcaatg
     5521 aatatgatga atctattaaa atctgctatt ctaaatgaag ggatcaaagg aaaaatgggc
     5581 gctatgcttt taaaagacgg cttacgttct ttgaaagcag aaatggatta ttccaaacat
     5641 ggcggtgccg ttttgtttgg cttgaaagca ccagtcatta aaactcatgg agcaacaggc
     5701 cccgatgctg ttcgctatac gatccgccaa atccacacaa tgcttgagac agatgtagtt
     5761 ggacaattag tcgaacaatt tgaaaaaagc gaagaatagt atttggatat ctgaagcaat
     5821 ccgttccatt gaaaaaaagg tggacattcc tgaaaaatgc cagtaaaatt agccatggtg
     5881 taggtaattg acaagtgtat gattcttgga ggtgaaaaag ttgactcgcg aagaagtatt
     5941 taacaaagta gcgaaaatta tttcaaatca ttttgagata gataccgata aagtgacgga
     6001 tgaattgaac atcaaagatg atttaaaagc tgattcaatt agtattatgg aattcgtttt
     6061 agagcttgaa gatgaattcg gtacggaaat ttcagatgaa gacgctgaac aaattgaaac
     6121 agtcggtggc gcagtagatt atatcagcag ccatcttaaa taatttcaaa taaaagcaaa
     6181 gaaggataaa aagctgcata cagcttttta tccttctttt tttaatcttt ttgacacgta
     6241 aaagtcattt ttctgataat tctggcgata aacagaaatt atgttgcaaa gtaaagcgat
     6301 tttctatata attattaata attcattaca caaagataag aataaccttt gttataaaac
     6361 gctttattct gtgtaatgtc cttttttatt aagaaaaact tccatttagg aagcagagag
     6421 gggtattcga ttgtccgata accaattatt agaagttcag aacctacata caggattccg
     6481 actcaaagat gactattacg atgcagtaga tgacgtttca tttactttag acaaaaacga
     6541 gattttagca atcgttgggg aatctgggtg cgggaaaagt accttggcta ctacgattat
     6601 gggattactt gatcctaata acacaaaaat tacaggtgag attttatata acgatctgaa
     6661 tttaatcgac ctgaacgaaa cgctctataa taaaatccgc ggaaatgata tcggaatgat
     6721 tttccaagat ccgttgtctg cattaaatcc tctcatgaga atcgaagacc agatcaaaga
     6781 aggactttcc tatcacacaa agatgaatgc agaacagcgt caagctcgtg cactagaatt
     6841 gctagaacaa gtagggattc ctaatcctgc gagagttgga cgccaatatc cccatgaact
     6901 atcaggcggt atgagacaac gtgtcatcat cgcaatcgca atcgcctgca aacctccaat
     6961 cgtcattgca gatgaaccga cgacagccct agatgtaacc atccaagcac agattcttga
     7021 tttactgaaa gaccttcagg aagaaacaaa aacagggatc atcttgatca ctcatgactt
     7081 aggagtcgta gcagaaatgg ctgatcgagt ggcagtgatg tatggcggac agttcgttga
     7141 agtagcaggt gtaaaagaac tgtttgatca tcctaagcat ccttatacac gctctttact
     7201 gaactctata ccacaagaag gaaatcatga tgcagaactc catgtgatcg aaggtgtcgt
     7261 tccttctctg aaaaacatgc ctcgtaaagg ttgtcggttt gcaccacgta ttccatggat
     7321 accagcaagc gatcatgaag aagagcctat ccttcatgaa gtcgcaccga accacttggt
     7381 acgttgctcc tgctataagc atttccactt tagagacgaa aaaggagagg tgtagatgac
     7441 agaattaatc acaatcaaag acctgaaagt tcattaccct attcgcagtg gattcttcaa
     7501 tcgagtaacg gatcatgtat atgctgtaga tggtgtggat tttattatcg aaaaaggaaa
     7561 gacatatggt ttagtgggag agtctggctc tggaaaatct actacgggaa aagccgttgt
     7621 gggattagaa aaggtaacag ccggacaaat catgtatgaa ggaaaagatg taacgaagcg
     7681 aagcaaccgc aaaaaaatgg gttataacaa ggatgtgcag atgatcttcc aagattcaat
     7741 gtccagtttg aatcctaaaa agcgagtgtt ggatatcatt gctgaaccca tccgaaattt
     7801 tgaacggtta agcgatcaag aagaaaagaa aaaggtaaaa ggactgctag atatcgttgg
     7861 gatgccggaa gatgcgctat ataaatatcc tcatgaattt tcaggcggac aacgtcaacg
     7921 tctaggagta gcccgtgctg ttgctaccaa tccaaaactg atcgtagccg atgaacctgt
     7981 atctgctctg gatctatctg ttcaagcgca agtattgaat ttcatgaaac gaatccagca
     8041 agaatacggc ctcagctatt tattcatttc acatgattta ggtgtagtaa aacacatgtg
     8101 cgacaatatc gcaattatgt acaaaggtcg atttgtagaa atcggtacaa gagaagacat
     8161 ttataatgac ccgcgacata tctatacgaa acgtctgctt tcagctattc cgcaaatcga
     8221 tgtagaaaat agggaaagcc acaaagaaaa tcgacgaaga gtagaacaag agtatatcca
     8281 aaaccaaaaa gaatactatg atgcgactgg tcgagtctac gatttgcgta cgatcacaac
     8341 tacacacaaa gtggcgttga aagatggagg tgcaagctaa tgtggaaaac gattctgcga
     8401 cgtgttttat tgatgatccc gcaagttatt attttaagtg ttctgatctt cttattagcc
     8461 caagcgatgc cgggggatcc atttaccggt ttgatcaatc caaatcagga tccggcagtg
     8521 atcgaacaga tgcgacaagc agctggcttg aatgacccat ggtatgtcca gtacttccgt
     8581 tggatcggaa atgctttgca aggcgatttt ggtcaaagtt tcttatacaa acgctctgtt
     8641 gctgacttga tcggcgaacg gatcatcaac actttatatc tatcgatctt gacagttgtc
     8701 cttacttatt tgattgctgt gcctctgggg atgcttgctg gccggtatca aaattcaatc
     8761 ttggataaga ttgtcgtaat ctacaacttc tttagttttg ctgttccttt atttatcttc
     8821 ggcttgatca tgctatttgt ttttggttat cgtttaggct ggttcccaac aagtggatca
     8881 caaacactag gtttgcaagg tggatttatc actcaatgga tagaccgttt gaaatatatt
     8941 ctgttaccat caattaccca agcatttttg gcgactgccg tcacaatcca atatctgcga
     9001 agtgaagtaa tcgattcgaa atcgctcgat tttgtcagaa cagcccgttc caaaggggta
     9061 ccgacgaata aagtattcag tcgacatatt ttccgaaatg cagcgttgcc gatggcttct
     9121 caaatggggt atgaaatcac ttcgttgatt gctggttctg tagttatcga aaagattttt
     9181 ggttatccgg gagtcggaaa actatttatt gattccatcg gccaacggga ctataccgtg
     9241 atcacatcct tagtattgat tttaggaatc gcgacgctag tggggacatt actttcagat
     9301 atcatcatga gtatcgttga cccgcgtatt cggattcaat aaaaccaatc agaaaggaga
     9361 atggatcgat gagtgaaaaa aacaatacag cagttcaaga aagtattcct cctatgggga
     9421 tacgaatgat tgctcgagaa tttaaaaaag ataaaattgc tattttttca ttaggtttgc
     9481 tagtggtttt attattagtg atctttatcg gtgcgatgct gaccgatcaa gacaaagtga
     9541 tgtatgttag tatcttcgac aaatacgctg caccaggaac agtttcgaca caaggacaaa
     9601 agttcattct gggagcagat gaaggcggac gtgatgtatt aggacaattg atcataggtg
     9661 ctagaaactc tgttacgatc ggatttgcga tcacgatcct tacttcgatc atcggggttg
     9721 gattagggat catctctggc tactacggag ggatcattga caacatcttg atgcggatcg
     9781 ttgattttat catgattcta ccgatcatgc tgatcattat cgtcttcgta tcgattattt
     9841 ccagatacaa tgtctggtcc tttatattca tcatgagtgc attttattgg gtagctaaag
     9901 cccgattatt ccgaagcaag acattatctg aagcaagaag agattatgtc agtgcctcaa
     9961 aaacaatggg aaccaatgat tttaaaatca tgttccgcga aatcatgccg aatctaagtt
    10021 cattaatcat tactaatttg acgatgaact ttgcggcaaa catcggtatc gagacaactt
    10081 tgactttctt aggtttcggc ttgccggcaa atgtacctag tttaggtaca ttgatcggtt
    10141 atgcaagtaa cggagaagtc ttagtgaatc ggcaatggat ctggttaccc gcatcaatcc
    10201 ttattttagt tttgatgttg agtatcaatt atgttggaca agcattcaag cgttctgcag
    10261 atgcgcgcca acggttaggc tagtatagaa gcgaaggggg aaataggaat gaagaaaacg
    10321 atttttggat ttgcagcgct gatgtctgct gtcgttcttg cagcatgcgg gggcggaggt
    10381 acagatacct ctggaaacaa ctctggaggc aacggcaata acaaagagga attaactttt
    10441 ccaattgcaa caaaaaataa tgatgatgca atcgaagacg gcgaattaga agctgcggtc
    10501 gcaacggaca gtcagtttaa aggattgttc cagtgggagt tttaccaaga ttcatatgat
    10561 gcagctttta tggctccttc tcatgaaccg ctatttgcaa acgatgacga tttcagaatc
    10621 acagacgacg gagctgcaac gcttgatcta gatgaagata cgaaaaaagc gacaatcaaa
    10681 gtaaaagaca acgtcaaatg gtcagatggt gaagatgtaa cggcggacga tgtgattttc
    10741 ccttacgaaa tcattgggaa taaagattac actggtatcc gttatgacga cactttccgt
    10801 aacatcgtag gtatggaaga atatcatgat ggaagtgccg acacaatctc cggaatcaaa
    10861 aaaatagacg acaaaacagt tgaaatcgaa tataaagaag taaacccaag catgcttcaa
    10921 tcgggtggtg gtatctggtc atatgcagca ccaaaacata cgttagaagg tgtagcaatc
    10981 aaagatatgg aatcaagcga tcaagtacgt aaaaatccag tgacttttgg cccttattac
    11041 atgagtaata tcgttgcagg agaatcagta gaatacttgc caaacgagca ctactggaat
    11101 ggtacgccta aattgaaaaa gatcacgatg aaatctgtac cgatggcaag tgcaactgaa
    11161 gcattgaact ctaaattata tgatatgatt ttccaaatgc caacagatac ttacgatacc
    11221 tataaagaaa ttgctggcta tacaaactta ggccgtgaac aaacttctta tacttatcta
    11281 ggattcaagt taggtaaatg gaatgcagat acaaagagtg tggaatacaa tccagattca
    11341 aaaatggctg ataaatcatt acgtcaagca atgggctatg cattagataa taatgcagta
    11401 ggtgaacgtt tctatgcagg tttgagaagc aatgcgactt cattgattcc tccagtattc
    11461 cagtcatacc atgatgatga gatgaaagga ttcacacaag atctagacaa agcgaaaaaa
    11521 ctattagatg atgctggcta caaagatgtg gatgacgatg gtttaagaga agacaaagat
    11581 ggaaataaac taacaatcaa ctttgcttcg atgtccggtg gggaaacagc gcaaccattg
    11641 gcagattact atatccaaca atggaaagaa attggtttgg atgtccaata cacaacaggt
    11701 cgtctgatcg aattcaattc tttctatgat aaattagaaa acgatgatcc tgaaattgat
    11761 gtttaccaag ctgcttggaa tacaggaact gatccaaatc caagtggact atggggacca
    11821 aatgctgcgt tcaactacac tcgttatgaa tcagaagaaa atacaaaatt gatcaacgat
    11881 atcagttcaa gcaaagcatt tgatgaagag taccaaaaag aagcatatca aaaatggcaa
    11941 caatatgcat ttgaagaagc atttgcgatt ccaacgttgt tccgtaatga agtattgcca
    12001 gtcaacgacc gtgtcaaaga ctgggattgg tcttatgatg taccaaaccc atgggcaaat
    12061 gtttctgtta cagcagattc acgttcataa tcactaaaaa tgaccgaaaa agggcgatgt
    12121 cctttttcgg ttttttgata tttttctgtt tatttctcta atattcaggt caaggcgctg
    12181 atttcatgac ttctccaata aacggtgttc aaagtccagt ttctcggtat taagtcaaat
    12241 ttatgcaaaa atatggaaag ccattttcac aaaatttttt cttcatactc gaaactaaac
    12301 gaatttttca caacttctcg tcaatcacta ggattattaa agctttactt accttttgac
    12361 cgaaccattt caaatttgac aaaaaaccag tataataagg aagtatcgaa aaaatatcca
    12421 taaaaggaat gtggaaaatg gacaaccagc tgacaaaaga actaaaagaa aactataaca
    12481 tcgtttttca cgatctaaat ttgcttgaac aagcttttac ccattcatcc tatgtgaatg
    12541 agcatcgcaa tctgcaatta tcggataatg agcgacttga atttttagga gatgccgttt
    12601 tagaactgat ggtttctcag tatttattcc gtttatatcc tcatttgcca gaaggaaaat
    12661 tgacaaaaac acgagctgcg atcgttcgcg aagacagctt gtcgaaattt gccaaagaat
    12721 gtcactttga tcaatatgtt ttgttgggca agggagaaga gaattcagga ggacgtacgc
    12781 gaccagcatt gctttgcgac ctattcgaag cttttttagg cgcgttatat cttgaccagg
    12841 gattcgacac gacccatgca ttcatcgaaa aagtgatttt tcctaaagtc aaagcaggtg
    12901 ctttttcaca tgagatggat cataaaacaa aactacaaga agtcttgcaa aaatcaggtg
    12961 atgtatcaat cgaataccga ttgatcaatg aagaaggtcc agctcatgaa cgagtatttt
    13021 ggatcgaagt ttatgtagat gatcaattga ttggcactgg acaagggaaa tcgaaaaaat
    13081 tagcagaaca agctgcggcg gaaaatgcat tggcagcact gtaaaagtaa gtgagggaaa
    13141 gctttgtatt tgaaacgaat tgaaatagcc ggttttaaat catttgcaga caagacagtc
    13201 attgattttg aaaatagcgt cacagcagtg gttggaccaa atggcagcgg aaaaagcaat
    13261 attacagagg ctatccgctg ggtattagga gaacaatctg ctaaaagtct gcgaggcgga
    13321 aaaatgccgg atatcatctt tgccggttcc gatacccgta agcagctgaa tattgcagaa
    13381 gtcacagtga ttttagacaa tagtgatcat tatctgccat tggagtacaa tgagatcagt
    13441 gtaacccgcc gttatcgacg gactggggaa agcgagtttt tcatcaataa acaaagctgc
    13501 agattaaaag atatccaaga attgttctta gattctggat taggaaaaga atcgttctca
    13561 atcatttctc aaggaaaagt agaagcgatt ttcagtagta aaccggaaga ccgtcgtggg
    13621 atctttgaag aagcagctgg tgtcttgaaa tacaagcagc ggaaaaagaa agcagaacag
    13681 aagctttttg aaacagaaga caacctcagc cgcgtccaag acatcatcca cgaattggaa
    13741 gaacagttaa ctcctttggc cgcccagagt gaggcagcaa aggagttttt acggctaaaa
    13801 gaaacactga ctcaaaccga tgtctctttg atggttgctg aaatcaagac agcaaaaaaa
    13861 gattgggaca acaaacaagc acagcttgcg aaattcaatc tagaattagg caaactatct
    13921 gagtcgatcc aagaacaaga atccattttg gcgaagcagc gtaaagaaaa tgcgcaagcc
    13981 gatcgtctga tcgaaaaaaa tcagcaagta ttattagatc tttcggaaaa actgaagcag
    14041 acagaaggac aaaaagatgt tttgcaggag cggacaaagc atacacaaaa aagctcgcaa
    14101 gaatatcaaa cttcattagc agaagcacaa aaaaaggtta aacattttga aaagcttcaa
    14161 gaaagcttga tgaaagcagc agcagaaaaa gaaacagaga tccaaaaagc tgaagcaaat
    14221 ctcataaaaa cacagcaaga attagaaaaa taccaaaaat caacgaaaga attattggca
    14281 gaattaagag atcaatatgt tgatttgatg caagaacaag cagctgtagg aaacgaactg
    14341 aagtatctag aacgtcaata tatacaagaa acagcaaaaa gcaagcagac gttagccaag
    14401 caatcggaag tagaagcatc agtagaccga ttgatcttac aaaaagaaga attgacacaa
    14461 aagcaggcgc agctaaaatc atctttaact gaaacaaaag agaagttaga aatgatccaa
    14521 caaaacggga aaaagttcca agaagcatta gcaaaagaac agcctaaaat gtatcaatta
    14581 atgaatcaag tccagcagct acgtgctcgt aagaaaagcc ttcaagaaat ccaagaaaac
    14641 tattttggtt tttaccaagg ggttcgattg gtcttgcagc ataaacagca gctttcgggt
    14701 attgtcggag cagtggctga actgatcgat gttcctgcag atttcacgtt agctatcgaa
    14761 gcagctttag gtggggcagc ccagcatgtc atcgttgaaa atgaaaaaga tgctcggcaa
    14821 gccatcacgt atttgaaaca gcaaagagga ggaagagcaa cattccttcc actgacgaca
    14881 atcaaaccaa gacaattacc ggctcatata ttgacacaag cagcagctgt agaagggttt
    14941 atagggattg ccagtgaaca agtcagttat cccgatcaaa tccaaactgt ggttcaaaac
    15001 ctgctaggaa cgatcctttt agccaaagac ttaactagtg ccaatgcaat cgcgcaaacg
    15061 atccgctatc aatatcgagt ggtttcctta gaaggtgatg tgatgaatgc cggaggatcc
    15121 atgacaggtg gagcgaataa acgaggaaac caaggcagtt tgtttgtaca aaatcaagaa
    15181 ttgaaacagt tgactagtga atttgaagaa gcagataaac aactccaagc acaagaaaaa
    15241 aaagttcagg agctgcaaca agaaacagct cgtttagccg aagaacaaga agttttgcgt
    15301 acacgaggcg aacaattacg ttttgaagaa caagaagcga caaatcagct acaaaacatc
    15361 ataaatgaac ttgaacgttt tgaaaaagaa aagcaaatct caacttttga gacacgtgaa
    15421 ctgcagcagt ttatcgaaga ttacgaaaag caaacgaacg aattgaaaga caaacaaaca
    15481 gatcttgaat cgcaacgaca aaaaatcgac gaagaaatca aatcgttaag tcaagaaagc
    15541 gaccagatgg aagccagaag agcacaagta caaagtcaaa aagcacaaga acaagcagat
    15601 cttgctgtct tgaaagagca gtttaatcat ctgcagatcc agctccgcgg tgcccgagtc
    15661 caaaaagcag aggcaaccga acgtcaagaa gcgatagaaa agcagttggc gacattgaca
    15721 gcagactttt ctgatcatga agtcacagaa gaaagtttgg aaaaacaaat taacgaatta
    15781 tctgctcagc gagaaacatt aaaagccgag ttggcaaaag ccaaagagca gcgagataga
    15841 aggcaaaagg agatcgataa gcttgaagca gtcttggcag agcgtaatcg tgagcaaaaa
    15901 gcacgactgt cggaacaatc caaattagaa gtccaaaaag accgagctga aatgatttta
    15961 gataatcatt tgacctatct gcagtcagaa tatcagctga catttgagaa agcttcccaa
    16021 gactatcaag aaacaaccga tatcgaagac agtagaacaa aggtttcatc cttaaaagaa
    16081 cagattgaaa aactgggacc agtaaactta aattcaatcg aacaatacga acaagtcagt
    16141 gaaagacata cattcttagc aacacagcga gatgatctgt tagcagcgaa aaaccaattg
    16201 tttgaaacga tggatgagat ggatgatgaa gtgcggacaa gattcaaaga agtatttgaa
    16261 gctatccgtc aagaattcaa aattgtcttt ccaaatatgt ttggcggcgg taaagctgaa
    16321 ttagtactga cggaaccaac tgatttgctg aaaacaggta ttgagattga agtacaacct
    16381 cctggcaaaa aactgcaaag tctaagtttg ctttctggag gagaacgagc acttacagcc
    16441 atcgcgttgc tcttttccat tatccgtgtc tgtcctgttc cgttttgtat cttagatgag
    16501 gtagaagcag cgttagatga agccaacgtg aaacgttttg gtcgttactt gagcgatttc
    16561 caagatgaca cacaatttat cgtagtcaca caccgcaaag gaacgatggt cgcagcagat
    16621 gtactgtacg gagtgacgat gcaggaatcc ggtgtatcaa aaatcgtttc tgtacggatg
    16681 gaagatatca atgaagaggc gaaaatcaac gaaacgaaag tgtaggaacg aaaatgatca
    16741 aattagtagc aatcgatttg gacggtacat tattaaatga acaaaagctg atttcagatg
    16801 agaataaaca agcattagca caagcaaaac agcaaggggt caagatcgtt ctatgtacag
    16861 gacgcccctt agctgcgatg gcgcattatc tgcaagaatt aggactggta gatgaaggtg
    16921 actacagcat cactttcaac ggcggtttgg tacaaaaaaa tgatactggt gaaatcatgg
    16981 aaaagaaagt gatggaagta tcagatatcc aacgcttata caaactggct cagcaattgg
    17041 atctgccact agatgttttg tctgacaatg tggttttaca gctgcctagt gccccaagga
    17101 agcaatcctt gtacaatgtg ttgaataagc tgctgcaatt ccaaccagcg gatataagcg
    17161 atattacaga tgaatttgtg cttaataagg cagtaatcgc ttatgaccaa gaagaattag
    17221 atcctaaaat caaagaaata ccagcagaat tccatgaaat gtatgagatc atcaaaacaa
    17281 gaagtatgct tttggaattt atgccaaaag gtgttacaaa agcttatggt atttctttat
    17341 tggcaaaaga tcttggtttg aaacaagaag aaatcatggc gatcggtgat gaggaaaatg
    17401 atttaccgat gatccaatat gctggactag gcgtagcgat ggagaatgct gtgcctttcg
    17461 tcaaagaagc agcagatttc gtgacagcca gcaatgaaga aaatggcgta gccaaagtga
    17521 tccaaaaatt tgtattagag tagggggagt caaatgggat tttttgataa aatcaagcgt
    17581 gcttttactg gcgaagagaa aacagaagaa gttgaagtac aggagaagta cgacaagggt
    17641 ttagaaaaga cgcgtaaaac atttggtgaa cggatgaatg agttgtttgc caattttcga
    17701 acagtcgatg aagacttttt tgaagaatta gaagaaacac ttatcggtgc agatgtaggt
    17761 tttgaaacag cgatacgaat caccgaagca ttacgtcaag aagtgaaact cagaaatgcg
    17821 aaaaaatcgg cagaagtcca aaatgcgatc atcgagaaac ttgtggatct ctatgaagcg
    17881 gaaggaatca atgaagtaaa tgaactaaat atccaagaag acggactaac agttattttg
    17941 tttgtcggtg ttaatggtgt agggaaaaca acaagtattg gtaaacttgc ccatcagttc
    18001 aaaaacgaag gtaaaaaagt attgatggca gcagcagata ccttccgcgc tggagcaatc
    18061 gaccagttag ttgtctgggg cgaacgcgct ggtgttgaag ttgttcgtgg caatgcagga
    18121 ggcgatccag cagctgtcgt attcgatgct ttggaaagag caaagacaga gcaggcagat
    18181 gttttactag ttgatactgc aggccgactg caaaataaag tgaacttgat gaacgaatta
    18241 gaaaaaataa aacgagtaat ccagcgggaa ttaccagaag caccccaaga aacacttctt
    18301 gtattagatg caaccactgg tcaaaacgcg atggttcaag caaaacaatt caaagaaaca
    18361 acagatgtga ccggtcttgt tttgacaaaa ttagatggta cagcaaaggg cggtatcgta
    18421 cttgctatcc gtaatgaatt gcatttacca gtgaaattgg tcggtcttgg tgaaggaatc
    18481 gatgacttgg agccgtttga tccaaatgat tttgtcgttg gattgttcaa aggattacta
    18541 aaagaagaat aacccatgtc taaaaagcag gagctgtgac aaaagttgca gctccttgtt
    18601 tgaatgattg tttttaacat agctgtgttt ttgatgcctt catttttata cttatttgta
    18661 agcggttctc aaacaatttc gttctttttc ttagactttt tgattataat tagattcata
    18721 tgaattggag gtcacttaat gatgaatttt aagcaattat tattgcatgt caatgcgcgc
    18781 ccttttatcg accaagctcg atttggtata gaacgggaag gacagcgggt tgatcttgca
    18841 ggaaatctag caaaaaccga tcatccagca atctttggcg atcgatccta tcacccctat
    18901 atccaaacag attttagcga aacacaaaca gagatgatca cccctgttac cgattctatt
    18961 cccgaattat ttcagtatct cgctgctgtt tatgatgtga ctgctcgttc tataccgaaa
    19021 gaagagatga tctggccatt aagtatgcca cctgccttac cggaaaaaga cgaagagatc
    19081 attattgcaa aattaaaaaa tttcgaagat gtcttgtatc gacgttattt agcaaaaaaa
    19141 tacgggaagc gaaaacagat ggtaagcggt attcatttca attttgaatt tggcgatgag
    19201 ttgctaagaa cattgttcag ccatcaggaa gaatttcaag atttttccga attcaaaaca
    19261 gaactttatt tgaaaacagc gagaaacttt atgcgctatc gctggatgat cacttattta
    19321 ttcggtgctt caccaatgag tgagaagaac tactttttag atgaatcaca tccgcaagaa
    19381 cctgttcgca gtattcgcaa cagtgcgctg ggctatacga atcatccaaa tgtgaaagtt
    19441 tcctatgctt ctatgaaaca gtatttagca gatatcgagc gaatgatcga agaagggaaa
    19501 ctttcggagg agaaagaatt ttatacaccg cttcgtttcc gaggcggaaa gaaagtcgca
    19561 gatttagcaa caacaggtgt tcgttatatt gaattgcgga atatcgattt gaatccttat
    19621 gcaagattgg gtatcaatcc agagcaagtt cggttcttac aattattcct gatgtacatg
    19681 ttatggacag aagaaaaaga agactgtgac caatgggtag cagaaggtac gactcgaaat
    19741 aacaaagtag cactagaaca accatcagat caaacagaat ttcatcaaga aggtagagaa
    19801 attcttgaag gaatgaagca aatgctggtt gaattggatt ggttggattc tctttattta
    19861 gtagaggaag cattgactca aatggatcat cctgaacaaa cgttagcagc gaaactctat
    19921 caagaagcac agctatcgag tcagcaagaa gttgctgtgg cattgggaca tcaatattat
    19981 aaagaaagcc atgaacgtcc ctatcagttg gccggttttc gcgaaatgga actttctact
    20041 cagatattta tgttcgatgc catccaaaaa ggtgtccaag tcaaagtatt agatgagtcg
    20101 gatcaatttt tgcgtctgca attccaagac catgtagaat atgtgaaaaa tgcaaacatg
    20161 acaagtaagg acagctatat cgtcccactt atcatggaaa acaaaacagt aacgaaaaaa
    20221 gtcttaaaag aagctgggtt ccgggtacca ggaggcgcag aattttcatc catggaagaa
    20281 gcggtaaaag cttatccgag atttgccgag caggcatttg tgatcaaacc taaatcaacc
    20341 aattacgggt taggtatcac gattttcaag gaaggagcta gtctggaaga ttatcaagca
    20401 ggtttagcca ttgcttttcg tgaagacagt tcggttttag tagaagaatt tatgccggga
    20461 acggaatatc gtttctttgt gatcgacgga gaagtccaag ccatcatgtt gcgagtccct
    20521 gctaatgtta ttggtgacag tatccgaaca gtgaaagaac ttgttgaaga aaaaaatagt
    20581 gaccctttgc gtggaacgaa tcatcgtgca cctttagaat tgatccaatt aggtgaatta
    20641 gaacaattga tgttgaaaga acaagggttg acgatcgaat cagttcccca agccaatcaa
    20701 attgtttatc taagggagaa ctcaaatatc agtacaggtg gtgattcgat cgatatgact
    20761 gatgaatttt ctgaagctta caaaaaaatc gccgtttctg cggtagaagc actaggagct
    20821 aagattagtg gtatcgattt gattatacca gataaagaaa tcgatcctac aactgataaa
    20881 aaagcatatg ggatcatcga agcaaatttc aatccagcca tgcatatgca tgtttatcct
    20941 tttgcaggaa aaggcagaag attgacgatg aatgtattga aattgttata tcctgaagta
    21001 ttttaaaaga aaaagctttt gacagattgt cctatttgat gtcaatctga tcaaaagctt
    21061 tttttgcatg taaaaattta tgtgtttttt cgttttaaaa taaacgatcc cagaagcttt
    21121 ttttcttttt tggtttttct ttttcagctg gcgaagagtt ttcttctggg tatttttttt
    21181 cgatatcaat cacaggttca tttactgctt cttttgctgt taagagcaat ccgaattcct
    21241 caggatttgc agtgacgtaa tcgttgacta cagtgaaacg gctattgttt ttcgttgcta
    21301 gctggatata ttggttttgg acagaaaggg gtagagcccc attcaagagt atggaagcat
    21361 ctggatgttt tttgagttct tttaaaaagt tttctttgtt ttttggttgg atcatttcag
    21421 caacagtcat actaagatag cagcgttccc tgaatgtccc taaatattta tgctgttctt
    21481 cagggttcac taaaggtgta ccataaagtc ccttatccaa atggcttttt acatcatctt
    21541 gtgccataaa aaataccctc cttcttctct ttgtctttct tacgattata gcatattccc
    21601 aataatacct aaaacatatg aaaaagcggt tgcttttgtt caacgattca cttaaaataa
    21661 gaatgaaaat cattctcaat tagaaaggtg gattggatgc gctacggacg actagtagca
    21721 ttattagtta ttttaagtag tatttcattg ttcatcggag tatcgaatgt acaattgtca
    21781 gaactgctcc agttagatgg gcaaagctta caaatcttgc tagtgactcg tttgccacga
    21841 acgatttgtt tgatccttgt gggagcgacc agtagtattt gtgggttgat catgcaacat
    21901 ttgacccaaa ataaatttgt ttcaccaacg actgcgggca cgatggatag tgcgcgttta
    21961 ggtattttag tggctatgat tttcctacct ggtgcatcct tgattgtccg atccttgaca
    22021 gcattttgct ttgcttttgc aggaacattg ctttttttat cccttacgcg attgttcctc
    22081 cagaaaaatc aattgatgct tccgttgatt ggagtcatgt tagggaatat cattggttca
    22141 gttgctactt tttttgctta tcaattccag ttggtacaaa atatgacttc atggcttcaa
    22201 gggaattttg cgactgtgat acgaggaaat tatgagttat tgtatgctgt tgttccattg
    22261 ttgctcttgg tttggctatt tgcttaccga tttacgatca ttggtctggg cgaatcgttt
    22321 gcagtaaatc tgggaataga ttaccagaag atgcagtttt taggcattgg cttagtatca
    22381 ttggctagtg cagtcatgtt gatcatggta ggaagcattc cttttatcgg agtgatcatt
    22441 ccgaatcttg tctctagaat atatggagat caagtgcaca aaacaattgg cgtaactgct
    22501 ttagcaggta gtttgttctt agtattttgc gatcttgtcg ctcgcgtgtt gatttttcct
    22561 tatgaaatac cagtcagtgt gatcgttgga atcatcggtg gggctatctt cctttatctt
    22621 ctgataaggg gacgacgata tgcttaaaaa aaagccatct atttttattg gtatgcttgt
    22681 tcttgtttta tttgttacag gaatgtactt gacgatccat acatatggaa actggcattt
    22741 tgcatgtgca ttgaggagta agaaaatttt tgcatttatc cttgtctcgc tagctgtcag
    22801 cagtgccaca atcagctttc agacaattac gcataaccag tttttgactc cttcagtatt
    22861 gggacttgag tcgttatatg tccttgtcca aacggtcctt ttcttcttta tcggaggagt
    22921 gacgatgctt cagcagacag gtacagtttt tttcttattg aacgttgggc tgatggtcgg
    22981 gctgagtcta ttgttatttt tctttctttt gaaaaaaatg agagcgaatc tttttttatt
    23041 actgatgtca gggatgattt taggtacgct ttttggtagt gtcagtacct ttttacaagt
    23101 catcatggat ccgaatgaat atgatttgct tcaaggcaga ttatttgcaa gctttggcaa
    23161 tatccagagt cagtatcttt tgcctgcttc tttgatcatt atcggctgct ggtacctgtt
    23221 atttcgatat cgacatgtgc tagacgtttt ccatctcgga aatgaacaag cagtaaacct
    23281 cgggatagac acagatcgtt ttgaattttt gattttatgt tgtgtcagtc ttttgacagg
    23341 gacatcaacg gctcttgtgg gtccagttac ttttttaggg tttattgtcg caaatatcag
    23401 ttatcgtgtc ttttctactt atcgtcatgg tcagctattt atcggaagct ttctggtagc
    23461 tatgctgttt ctgacaggag gacagctcgc agtagagcag attttcggct ggaatacaac
    23521 agtgagtgtc gtcgttgaat ttgtcggagg aatttatttt gtcacaaaat tgattcgcga
    23581 aaggaagagt atcctatgat tgatttacaa aaggtcaata aactgtacca tggaaaatca
    23641 gtggttaaag atgtacagtt aacgattcct gaaaagaagt tgactgcttt tatcggtcca
    23701 aatggtgctg gaaagtcaac ggtgttgtcg atgatcagtc gtttgatacc aaaagataca
    23761 ggtgaaatct atttagacca taacgaagta aaggcttgga aatccaatga attagccaaa
    23821 aaattatcga tcctacgaca atcgaatgaa ataaatgtcc aaatcaccgt gaaagaatta
    23881 gtagaatttg gacgatttcc ttatacgaaa ggaaaattga cgacaaaaga cgaggaaatc
    23941 gttcaggaat cactggaaca ccttgggtta gaagaaatag cggatcaatc gattgacact
    24001 ctttcaggcg gtcaactcca acgtgcgtat attgcaatgg tgctagcgca agacacggat
    24061 tatattttac tggatgaacc tttgaacaat ctagatatga attttgcggt tcaaatcatg
    24121 cagattttaa aaaatttagt acaagaaatc gggaaaacaa ttgttattgt tcttcatgat
    24181 atcaactttg ctgcaagtta tgcagacgaa attgttgcaa tgaaagatgg acagttattt
    24241 acgcaaggaa cgacccaaga aatgataaaa aaagatgtat tggatgaatt atacgaaatg
    24301 gacatacgga tttgtgagat tgaaggccgc agattctgtc tttatttcta aaactaacat
    24361 taggagagaa gagatgaaaa aattagtagt aggtatcttg attctagcat catttggttt
    24421 agcagcatgt ggaaatagca acaacaccag tcaggcagac acaaaaaaaa gcagcacaca
    24481 aactgaaact acattgacga taacagatag taatggagac caaatcgagg tgccaaataa
    24541 tccagaaaaa gtcgtcgtat tcgacaatgg ttctttagat acgatggatg ctcttggtgt
    24601 tggagataag gtagttggag cagctacaag cagccttcct gagtatcttt catcctataa
    24661 aaaagtagaa tcagcaggtg gaataaaaga accagactta gaaaaaatta atcagcttca
    24721 gccagatcta atcatcattt ctggccgaca aagagatttt caaaaagatc taagtcaaat
    24781 tgctccgacc attttccttt ctttagatgc gaaaaatcca tgggaatctt tccagcaaaa
    24841 tgtcactgct ttaggggaga tctttggtaa gcaagaagaa gctaaaactc aattagagga
    24901 attatctagt gcaatcgatc agacgaaaaa gaaagcagaa gctactgaca aaaaagcact
    24961 agtcacactt gtgaatgaag ggcaattatc agcctacgga tctggttcta gattcggttt
    25021 catccatgat ttatttggct ttgaacaagc agatgatcaa atcgaagcat ccactcacgg
    25081 tcaaagtgtt tcttatgaat atgtgctgga aaaaaatccg gatatcttat ttgtagtaga
    25141 cagaacaaaa gctattggtg gagacgacag caaagatgat atttctgcca atgaactggt
    25201 agcacaaacg aatgctggta aaaatcagca gatcatctcc cttgaaccag atgtctggta
    25261 tttaagcggg ggcggtttag aatcaatgaa actgatgatc gaagatgtga atcaagcatt
    25321 taaatagcat aaataacaga ggattaaact ctcatactat gtaacaataa tgtttcttac
    25381 attcttaaat agcaagagcc tatcctcaaa gaagttatca aaaaccatcc gtaaaatcgt
    25441 attgatgatt ttacggatgg tttttattta tttgagaaat cttttttcaa cgtgaattca
    25501 ttatctacat catacgggtt gattctagaa tggggagtgg caaaaaatag tgtgatccat
    25561 tttttcagca tcaagatcgc ctcctttgat ttgaatcaaa ggtacaaagc gaaacttaga
    25621 taaaacttaa atttagatat ttttattttg taccgatctc ttctttaaac gatgttccat
    25681 ctgctgcttc tcggcaataa gtccactaga ctagaaaata tgagaagcta ttttctgtcc
    25741 agcgttctta ttactcaaaa caaatcgcag ttgtcacaat ctcttctaaa cgatgttcca
    25801 tctgctgctt ctcggcaata agcccactag actagaaaat atgagaagct attttctgtc
    25861 cagcgttctt attactcaaa gcaaatcgca gttgtcacaa tctcttctaa acaatgttca
    25921 atcagctgac cttcggtatt agctcaaagc actgatttca caacctctat ttaggcatgt
    25981 gtctcagcaa gcggttgata gttgatgatc tgcatttttc gataaaaatc ggcgggaagc
    26041 ttactccacc gttttagtaa ttgatagaaa taactctctt ctgctttgat tttatactcg
    26101 cttaatatca atccaaaact attcgttttt tttgaagcta attttttata aatatccaat
    26161 gctttggttt tatcttcatt gacaaagagt gtttttactt caatataaga accctcgata
    26221 ttttgtgttt cttcgataaa atagatgttt tttatatatt ccttcatagt gattcctcca
    26281 aagaagtctt ttatttgata agtttactct accgaagagt tgttaataat ccgtgaacaa
    26341 aaagtaattc tttttccaat agttgttaaa ggttttttat tttttatagt attttttgtt
    26401 atttaagaaa ggaataaggt taaacaaata acaggttgct ttttgggtct ttttccgttc
    26461 aagaaactga acgaagaaaa gggaaagttg tctcttttgt gataagagaa atcataataa
    26521 acgaatgact tactttccaa taaattgaga acagtcagaa ccagacaaat tagttgcatc
    26581 tgatgaataa agtgattatt ctatgacatg aggtgataca gatgaaatta gaagtgacaa
    26641 aagaagcaca agaagtattg aagaataaat tagaagcaga cgatcaactt ttattagata
    26701 tcgaaaacgg tgacggtcca tttgcagaaa gccaagtcag ttgccaattg gatacggcat
    26761 ttcgattgat cattgtcaaa aaagatacac aaacagatct aagtctttat tctgtagtgg
    26821 ctgatacacc agttggacca atcaaaatca aagacagtgc aatactttac atggatgatc
    26881 catccacact tgctttagaa ccaacttata atagtttaca attaaaagga ccaagcggct
    26941 tgagaaaagg caacttgcaa gttgttcgaa aagactagag ggataaaatg ggaaaattgg
    27001 cgatcatcag cgacctacat gtggacatca ataaattcgg cgaatcagag ctgatgcagc
    27061 tttggcaagt tttgcaaaag cacaagatca ctcggcttca tctagccgga gatacggcta
    27121 ataaagtaga ccgttgccta gctgttgtcg aatttttcgt caataaagga ttatctacga
    27181 catttcattt cggcaatcac gagttggcag atgtgcccaa tgaacagatg atggaccatt
    27241 ttccagaccc acatttttta aatgaacggt atattgcttt aaatgagcag accgttcttt
    27301 tagggatgaa tggctggtac gactatcagt tttccgaatt gaaagattac gaggcaatcg
    27361 tacgaatgaa gcgtttgtat tggtatgatc ggttcatcca gcgtgggaaa acagatctcg
    27421 aggtcaatgc agaaatgctt gcagctgcaa aaaatttgct agaccagctg gaagcaaaaa
    27481 aacttgaggt gattttatcc actcatttcg ttcctaaacg ggcatttatc atgtatcaat
    27541 ctgctcctta tgagcgttgg aacaaattaa atgcattttt aggatcagaa tcattcggag
    27601 aattacttga ccgttattca aatatcaaac aagtagtttt tggccatacg catcgtcgct
    27661 ttgaagataa atccatcggt cacacgattt acagctgcag accttttggt tattattatg
    27721 aatggcagct gacccgagat tttgtcttga aagaacagtt gctagacagc tatgatccta
    27781 tgaaattacg tgtcctcttg cgtgcccatc acccagcttt tcaggcctat caaacacaac
    27841 atttgcaaga ggaatttgaa caagcgatga caatcgttcc gtattgagac agcattagta
    27901 atgtgtaaaa gaaaatacct tgtaaaacat aaggataagt aagagcagta gatccattta
    27961 tcgtggatat gctgcttttt ttgcggaaaa taatcagcga atgtttattt gatcggatga
    28021 tttgtaactc gcagagtact agatgcaagc gtgtattctt tttttgaacg ataatcacaa
    28081 aaaaaaatat aatatacatt ttttatttaa ttataattaa tattgattga agtctaggca
    28141 gtcaagtcac attttgatag ataggagggg gacttacgaa ttattttaaa ggctatgaca
    28201 gctgtatttc tagattgtgt ttgcatcaag ttgcaataaa aactagaaat caaatcgggc
    28261 tgataatcat ttataactaa tcgatacata ggaccaaata taggtctatg ttcttttatt
    28321 tcataagtat cgtaaaacag aattttgcta tggattaatc caatcgactg atatgtttag
    28381 taaataaaga aagaggaatg tcaatgatga aaaaagaaat cgtattaaca gcagcaatga
    28441 tgttattcag catggtagca agtacgactt ttgtttctgc aactgaagta tacccaaagg
    28501 aatataacac agaaggaacg attacatttg aagcaggaga tgagggtgta actcctcctg
    28561 ttgatccaga gaatcctgat cccaataaac ctgtcgatcc atcagatcct ccaagccctg
    28621 gaacaggagg ggcattatcg attgattatg gatcaaaatt caaatttggg actcaaaaaa
    28681 tttctactgc ggataaaacg tattatgcag ctgctgatgt gatgaacgat gggtctagaa
    28741 aaccgacata tgtccaagtg acagatagga gaagtacctt atctgggtgg aaattaagtg
    28801 tctctcaacc agaacagttt aaaactgcca gtggggatga actagttgga gcacagctga
    28861 aatttacgaa agggcaggct gtttctttgg ttgatccaac atatacgccg caaacggtga
    28921 attctgaatt aacgttgaca ccgggaggaa acaatacgtt agcaattaat gctaaatcag
    28981 gaacaggtgt ggggacttgg gtctatcgat ttggtgcaaa tgaaaatgaa aatcaagatg
    29041 cggtacagct ttcggtaccc ggtaaatctg tcaagttagc gcaacaatat tccactaaat
    29101 tagtttggac attagaagat acacctaaca actagtttac tgaaaagaac tgttaaaaat
    29161 aaatacgtag tcatattgtc ttgcgaggta atcgagcaaa aattgtcaaa ggctaggcta
    29221 aatttgtttg gatacgaata gttcatctag gaatttaacg atcaggagga aaagatatat
    29281 tgaaaaagag gaggatcgtg ctcattttaa gcagtctctt agtgactaat atctttccga
    29341 tcatagggta ctctttggaa ttgaatcagt tggagcatgg aaatagaaga gacgaagaaa
    29401 gcaaactcac ttcgacattc gacagtttaa tagaatccaa ccagacacaa gaaagcagtg
    29461 aggatttaag tatttcgagt agtggagaga ccactgacaa cgtagaagct gagggttcgg
    29521 acaaacaagg actagaagat gcaccaattt ctgcggttga gctgcctgac gatcccaata
    29581 ttatttctat cgataaaatt tttcaaacac ctatcggtac tagcacgtcc atattggaaa
    29641 atgggaagtt actgcagttg aacccagcag aaaggtctca aagaggagct atttggtcaa
    29701 ataagaagat tagtttactc tcggatttta catttaaatc ttatttatac ttaggaaatc
    29761 aacgagatag agcgggagat ggcatgacct ttacattgac tggcgatcct agaatggcta
    29821 gtaatcccag tcaagttatt ggatcgccag gtatgggaat tggctcatat tctactcgtt
    29881 ctggccaacc ttacattgcg aatgcgctct cgattgagtt tgatacgtat aaaaatagtg
    29941 gttcttctga tcgaatggat cgagagataa ctgctgataa tagagggcat ggacatgtcg
    30001 cttttgtcac gcctaaacca aataataata attattctgg agagcatact ggcgtgacgg
    30061 tagctcctac atttctttct aatggcacat ggcgcttgtt aataattaaa tgggacgcgg
    30121 agcaaagaag tcttacttat gatttggaag gtgtcggtcg ctcttctcgg attatacctg
    30181 atctcattag gcagtttggt tctacagaag taaattgggg gtttacttct tcaacaggta
    30241 ctttttttca agaaaatgct gtcgctgtca cgcgacttcc atcgaatgtc acatcaacag
    30301 ctgatgtaaa agtcaacgat agtgattatg gggccatcgc tgaagctgga ggaaacgata
    30361 agataactat cagaaataca ttgaaggtcg agggggattt tcttgaatat aagaaaatgc
    30421 agactagtat cgacctccca caagaattaa ctattcccga gcatatcttg atcaatggaa
    30481 atcaaattga tgccaaagat atcttgataa ccggaaatcg agtcacgcta aatctgacag
    30541 attattttat tgctggagat acgttaataa tcgaattgga gacaactttg caggaagtaa
    30601 ttcctgaaaa agtactcact atgcattttg aataccttga aaacgggaat ttgattgagc
    30661 aatcgaatga aataaaccta aagatcgcaa agctgaagga gatagatatc catgtttatt
    30721 ataaagataa agacagtcag attgatattg ctgaaatgaa aacaatcact gggaaaatag
    30781 gagagaagta taaagaaact cctattgata ttgaagggta tgtttttgac tcggattcag
    30841 cgaatacaga aggcatcttc tccgaaaata cagaggatat ctatttttat tacagaaaag
    30901 gcaaacttta tctctcaact gctcctcaat atgtcaattt tggaaaacat aaaatatcca
    30961 gtagaccatt aagtgaattc ggacagtttt caggtgggtt gaaaattata gatgaacggg
    31021 cttttggaag ttggaaatta caattgaaac aagagaaagt tcttacaaat ggagattttg
    31081 agcttccaga agctctttcc tttgttacct ctgaaaatac aacggttata gggacatccg
    31141 ctgttacgat tttcgaaagt gatcaaaagg gtgaaagcga tttgtcctct cttttagatt
    31201 ctacagctca tcgtggaatc agaataaata ttcctgtaga aaaccaaaga atcggaacct
    31261 ttgaggggaa actatcttgg atacttgcag atgtcccagg aaattaacag gaagagaaga
    31321 atataacaaa attattgagt ttcaagaagg gcacaggtac cataggctct tgtgtcccac
    31381 agagacaaga ttttgttata gtcttctctt acatatgatt aaaggagcga ttttcttgag
    31441 accaaaacaa caattattta taacactcct agttatttta ggggcacttt ttaacaatat
    31501 atcagtgtca gctagtgcat ttaatttttc agtgacgccg ataacttcag agaatcaaat
    31561 cgacaagaga aaaacttact tcgatcttca acttgatccg gatcaggaag tagaagtaaa
    31621 agcggaattg agaaatgata cagaaaaaga agtgaaaatc gatatttctg tgaatagcgc
    31681 aaccaccaat tcaaatgtga tggttgaata cggaaaaaac gagattgaaa aagacatgag
    31741 cctgatcttt gatctggtag attatgtgag ctatccacag atagtgacgc taaaacctaa
    31801 aagtgtccaa accgttgctt ttcatgtcag gatgccgaat gagcgatttg atggtgtatt
    31861 ggctggtggg atcacattcc aagaaatcca gacggaaaag gaccaaacag aaactaagga
    31921 tcaaagctta tcgattgaga atgaatacac ctatattatt gctttgttga tgcaacagac
    31981 actgaacgaa gttgctccga accttactct tcatgaagtt aaaccagatc aaatcaatgc
    32041 aagaaatgtc atcttagcaa acgttcaaaa tgatcaaaaa acctatatca atcaagtagt
    32101 tattgaaaca aaaattacaa aaaaaggaca ttctgaagtt ttatatcaag aggaaaaaga
    32161 aggattgcag attgcgccga atacaaattt ttcttttcca actgctttaa atggtcaacc
    32221 gctaacccca ggtgaatatc accttacaat gactgtttta ggaaatgaaa atgaaaatgg
    32281 aaaattttcg agaaaaaaag gaaatactac gatcaactat accaatcaat gggtatttga
    32341 aaaagatttt acaatagacg gaaaagtagc caaggaattg aacacgacgg atgttacgat
    32401 taaaaaagac aataattgga tttatatctt agtagcttca cttttcttat tgtttatttt
    32461 attatgcata cttttgtttg ttttgagaaa aaaagaagag aaagaaaagt aaggttaaga
    32521 taacaaatag taaattttta ttattgtagg atggttgggc tctttttata acaatataaa
    32581 atataccatt ttattaataa aaatgcatac tagtaaatga tataattcta ataacaggtt
    32641 tgatcgcgag aaaggccaaa taaaacgctc tccaaaatgt taaaaaaaag acaggacgat
    32701 gtatattata caaacaagaa tcgctgacaa cagtgactcg gatccaggaa atcagtttta
    32761 tccccagcta gttggtgaat gcatggaaag taatatacgt agaaagagct gatgactaat
    32821 gaattatgag ttttttttaa gcaaagaaga tcacagaagt tattcattac ttaaatattt
    32881 agaagcaagc tcaaatttat cagagtcaat atcgaatgtt caagaagagt tgtcgctatc
    32941 gacatttctc ttgaaaaaaa cgatcgataa gctgaaacat gatttacaaa agttcgatct
    33001 agagaaaaat ttgcgagtaa ccgtcagtga attggatata tgtctggaaa ttaatggaaa
    33061 atgttctagc aaagctctgt tatctcgtta tataacggat tctttatcta tgaaaatggt
    33121 attggctttc tttcaggaaa aatatatctc agtagaaaat tttgctaaac agcatcacgt
    33181 gagttattct gtggcttata aagtattaca aagactaaaa agaaatctaa aaaaatatca
    33241 aatttttttt gaaaagagaa agtt
//
LOCUS       DAIGSZ010000031        32846 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.031, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000031 DAIGSZ010000000
VERSION     DAIGSZ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.031"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            101..1242
                     /locus_tag="NOB31_001482"
                     /pseudo
     CDS             101..1242
                     /locus_tag="NOB31_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(1368..2447)
                     /locus_tag="NOB31_001483"
     CDS             complement(1368..2447)
                     /locus_tag="NOB31_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0973695.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(2556..2996)
                     /locus_tag="NOB31_001484"
     CDS             complement(2556..2996)
                     /locus_tag="NOB31_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0973696.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(3053..3463)
                     /locus_tag="NOB31_001485"
     CDS             complement(3053..3463)
                     /locus_tag="NOB31_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCI0973697.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(3644..4078)
                     /locus_tag="NOB31_001486"
     CDS             complement(3644..4078)
                     /locus_tag="NOB31_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0973698.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(4178..5026)
                     /locus_tag="NOB31_001487"
     CDS             complement(4178..5026)
                     /locus_tag="NOB31_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0973699.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            5415..7181
                     /locus_tag="NOB31_001488"
     CDS             5415..7181
                     /locus_tag="NOB31_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HCI0973700.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            7283..8542
                     /locus_tag="NOB31_001489"
     CDS             7283..8542
                     /locus_tag="NOB31_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0973701.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            8689..9990
                     /locus_tag="NOB31_001490"
     CDS             8689..9990
                     /locus_tag="NOB31_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0973702.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            9993..10844
                     /locus_tag="NOB31_001491"
     CDS             9993..10844
                     /locus_tag="NOB31_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0973703.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            10857..11672
                     /locus_tag="NOB31_001492"
     CDS             10857..11672
                     /locus_tag="NOB31_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HCI0973704.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            11823..12989
                     /locus_tag="NOB31_001493"
     CDS             11823..12989
                     /locus_tag="NOB31_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0973705.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            13219..13866
                     /locus_tag="NOB31_001494"
     CDS             13219..13866
                     /locus_tag="NOB31_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCI0973706.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            13950..14894
                     /locus_tag="NOB31_001495"
     CDS             13950..14894
                     /locus_tag="NOB31_001495"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HCI0973707.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            15029..16480
                     /locus_tag="NOB31_001496"
     CDS             15029..16480
                     /locus_tag="NOB31_001496"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HCI0973708.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            16501..17337
                     /locus_tag="NOB31_001497"
     CDS             16501..17337
                     /locus_tag="NOB31_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCI0973709.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            17337..17996
                     /locus_tag="NOB31_001498"
     CDS             17337..17996
                     /locus_tag="NOB31_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI0973710.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            18122..18811
                     /locus_tag="NOB31_001499"
     CDS             18122..18811
                     /locus_tag="NOB31_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973711.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            18817..19773
                     /locus_tag="NOB31_001500"
     CDS             18817..19773
                     /locus_tag="NOB31_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HCI0973712.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            19817..20329
                     /locus_tag="NOB31_001501"
     CDS             19817..20329
                     /locus_tag="NOB31_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0973713.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(20585..21133)
                     /locus_tag="NOB31_001502"
     CDS             complement(20585..21133)
                     /locus_tag="NOB31_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0973714.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(21222..22403)
                     /locus_tag="NOB31_001503"
     CDS             complement(21222..22403)
                     /locus_tag="NOB31_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HCI0973715.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(22639..24147)
                     /locus_tag="NOB31_001504"
     CDS             complement(22639..24147)
                     /locus_tag="NOB31_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HCI0973716.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            24306..24497
                     /locus_tag="NOB31_001505"
     CDS             24306..24497
                     /locus_tag="NOB31_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973717.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            24700..25617
                     /locus_tag="NOB31_001506"
     CDS             24700..25617
                     /locus_tag="NOB31_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HCI0973718.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            25610..26683
                     /locus_tag="NOB31_001507"
     CDS             25610..26683
                     /locus_tag="NOB31_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973719.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            26831..27349
                     /locus_tag="NOB31_001508"
     CDS             26831..27349
                     /locus_tag="NOB31_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973720.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            27330..27722
                     /locus_tag="NOB31_001509"
     CDS             27330..27722
                     /locus_tag="NOB31_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HCI0973721.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            27798..28733
                     /locus_tag="NOB31_001510"
     CDS             27798..28733
                     /locus_tag="NOB31_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HCI0973722.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISDSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            28866..29645
                     /locus_tag="NOB31_001511"
     CDS             28866..29645
                     /locus_tag="NOB31_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCI0973723.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            29638..29955
                     /locus_tag="NOB31_001512"
     CDS             29638..29955
                     /locus_tag="NOB31_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCI0973724.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            30199..31809
                     /locus_tag="NOB31_001513"
     CDS             30199..31809
                     /locus_tag="NOB31_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI0973725.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            31966..32814
                     /locus_tag="NOB31_001514"
     CDS             31966..32814
                     /locus_tag="NOB31_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI0973726.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        10854 a         5878 c         6406 g         9708 t
ORIGIN      
        1 tgtttttttc ataaatttag acaaaaaaac agtaaacata taggtagaat ctctactatc
       61 ttatttcttg catacaaaaa aatcaaggag tgagagagtt atgagatatt caaccatctt
      121 aatatcaaca tttgcagcct taagcttatc gcttactata aatcagacag tccacacaga
      181 ggagacagaa acagccaaat ggacagaaac caagtgggcc aacgtcaatc gaattacctt
      241 tcaggatgaa ttttcatcct tcaattcagg agtcgcaaaa ttaagaaaag gacaaacagc
      301 gaccatcaaa gcaaaaattg actattcggg agacttagca cctatactac aatcagctgt
      361 tacatttgag aatgttgatc ccactttgtc gattggctat gacgagaaca ctttgactat
      421 ccaacacaag caagcgatat ttaccttcac cgttacatta aatcaggact tgttaaaacc
      481 agcgcttttt actgtcaagg tatcagatgg actaccgaac gatcatcatt taacgccgta
      541 tagtcagcgg cagacaattg agcaagattc agccatcgac tcaggaggag atcttgttga
      601 agaaccaaca gataaaccag aaaatgaaaa taagccagaa gtaccgccta cagaaaatcc
      661 agacggagaa cagaaaccgg aaatagaacc tggagaagaa cccgatacag aaactcaacc
      721 agagccagac aataaatcaa aacctgaaat aacccctgga gaaaaaccag atgtaactcc
      781 agaaccagat acggattctg gaaaccaaac agtaccggaa acaaatccag acacagataa
      841 tgaaactgaa aatccagaaa aaccagaggt agatccagaa gaaaaaccag atgtgactcc
      901 agaaccagat acggacgcaa gagaccaagg aataccagaa aaaataaaca aaaaaacaat
      961 tcaagaggat ggaaaaaaag agagtaaaaa atcaaatcta gcaattctaa aaataaatga
     1021 agagcagctg aataaaaaat cacgaatatt tgatagcgcc caatcagctg aaaccttaaa
     1081 aagtagcaag gatacaacct ttgctgtcct gaaacgaaaa ataaacagct accaaaatcc
     1141 ggagagtcac aaaacaaagt tatactgtgg agcggaatca ttctattaag tatagcaaca
     1201 atgctttctg caaaaagatt taaacaaaac agatctctct aacatttgaa taatgtctgt
     1261 gaacgcattt ttcaaataaa aagaaatatc cagaaaatga ccccaaaata ccagattgaa
     1321 atctgatatt tggggtcgtt catactttat ctttcttcat atttatttta agggatatct
     1381 gtttcttttg gaagatggtt cgggatcttt ttcactttca atacatctaa aaagaaggta
     1441 aagatcggaa tgccgacaat caagccccaa acgccaaaga accgttcgct aacaagtaag
     1501 accacaaatg tataaaaaat cggcagttct gttttgctgg acatcaactt cggattcagc
     1561 acataagact caattagatg gacaatcaaa atcgtaatca ggatataaac aacatctcgg
     1621 atgcctcctt gggaataagc tatgaaagat agaggaatac aagaaatgat aacacctgct
     1681 actgggatca gacttaaaat gaaaatcatg atcgctaaac tcagcagctg atgaaagcca
     1741 aatacagcca aggcgattgt agtgagcaac gtatttaaaa gagcgacaac aaattgagct
     1801 tctaatacca aaccaaatgt attgacaaac ttatcggcaa aatagtaaat atcttgaaag
     1861 aaccaagaaa attcactttt taaaaacaat cttgagaata caattgtttt tttcttttca
     1921 atcataaaaa agaaacttaa gatgaatgac atagcaaacg ccactgccat ttttcctata
     1981 tcctgtaaat agccaagcgc aatcgaagcg ccattttgaa gctgttcaaa aaaatcgttt
     2041 cgctcaatat aagtatggat atattgtaaa acaggatctg catcttttgg ctgatgctcg
     2101 taaaaatcaa taacggactg gatcatatca aatgtttgat gaataagcat cgggatatac
     2161 tttgtgaatg ccagatagat aaggtaaacg atcagtgtat aaatcatgat agctaaaaca
     2221 cctgtaggga ttcggacaaa tcgctgaatg atttgaacaa gatgaatcat caaataagta
     2281 aagataaatg tgagcaaaat ggttgtaatc atacttctaa ctaagaaaag aacaaaaacg
     2341 acaaataata aaacagtgag acggcgtatt ttttcattcg ccaaaaaacg ctgataaacg
     2401 gtcaaatcga caacctccaa ataacaaaaa ataaacacgt tattcattat atgatggaat
     2461 atgaaaataa gaaagagaaa gagcaaaaag aaaaaccgct aaatgacgtt atcttatgag
     2521 ttggttttcc tcataaaatc gttcatctag cagtttcagc cctttttctg gtcttgatga
     2581 aaattatcta gcatttttcg ggtcagatgt tgcagtgtat ccaattcttc ctgttcaagt
     2641 ggaagataag acttgatctt ttgtggaata ccttctgctt gtttttgcaa cgcagcacct
     2701 tgaggagtca gcgtaacatt tacgattctt tcatcacccg tttcacgctg acgattaata
     2761 taattttttt ctgctaactt ttttagtaag ggagtcagcg taccagaatc cagacacaaa
     2821 tcatttccta gctctttcac tgaagtcttt ttcttttccc ataaaactaa catcacaaga
     2881 tactgggtat aggtaagatt cagcggcttg aggagggaag tgtagtgtct aatgatttcc
     2941 ttagaggcgg catataaagg aaaacatact tgattaacta aatatagatc ttccattttt
     3001 ccacctccgc tgttttacta tagtgtatca tagcggattt acacaaaaaa gtctattcac
     3061 taactgcttt cagagtaact tctatatttc cagctgtagc ttttgaatac ggacacactt
     3121 tatgcgctgc ctctaataat tcttgcgttt cttccagaga aagaccttcg atagatcctt
     3181 caatctctac acctaagaca aagctcgttt cactttctga ataaagggaa acttgtgcac
     3241 tgacagtaga agccccagag atattttttt gctgtttgat caattctaat gcactgttaa
     3301 aacatgcact gaaaccagct gcaaacaatt gttcagggtt ggttgcattt tcgacgcgtt
     3361 taccaggagc tgcaatattc aattcgaatg tacgatcggg attatgaact tctccagagc
     3421 gtccgcctgt gttgatcatt ttcgtagaat acattttttt cataaaatta ccacctttaa
     3481 ttatatttta tacaattgaa ttttacacaa tataattgtg gaaagcaaag aaatggattg
     3541 gcataagata aataagagaa agcacatgaa acagacgcgc tttctcgaat agcaaacata
     3601 tacaaaaaaa tatcagagac aaaaactaat ctcatcataa acattacata tatttctcaa
     3661 aaagttgttt tctttcttca aaacttactt cacgatggac ctgatgaagc atccataaat
     3721 aaccaaaagg atctctgaac attgagttag tcacaccaaa gtccatcatt tctgtcattt
     3781 cttgaatctc tacacagcca tttcgtaatg ctttattatg tgtgtcctcg atatcagaga
     3841 cgatgatatt gaaccagatc gtatttggat gttcagcagt aggagcagtc aaaccaagag
     3901 acgtgttttc atccagcata tggaatctcg tgccatacaa ggtaaaaatg acttcattat
     3961 tgcctctagg gtaatctgtt gcctcaatca gttgtatttc atcaaagatt gtttgataca
     4021 gttctagtgc tttcaaacta tcatttaata caaaatctat ttccgttcct ttatgcataa
     4081 agatctcctc tccttttcag tcgaacagtt actagattct tttattatac cagttaaaga
     4141 aaacgcattc aaaaaaatag cggatttact taccaactca ttcgattgga tgataagtaa
     4201 atccgcgtcc cattacttct gctacgctgc tgacaatgac aaaggcactt ggatcgattt
     4261 cttctatcaa tggtttcatt cgggaaaatt catgatcagt cacaacgatc aataaaacct
     4321 cttttgactt tcgattatac ccgccttttg cctctagcag ggtaaggcca cgtccaatct
     4381 cagcacttaa gcgaaggcgg atgtcttcca aataatgttc actcatgacc ataacagatt
     4441 tctttcgatt gatacctgtt tcgatataag tcatgacaat tgaagtgatt gcaatagata
     4501 aaatagcata aagaaactct tctattccaa aaacaaacag attaagagaa acaacgaatg
     4561 cgtctgtaaa aaataagcca atcgaagtat tcaagtggaa atatttttta aaaatgaggg
     4621 gagggatcgt cgtaccgccg ctagaagagt tgtttttata taaaatcgca actcctaaag
     4681 caaaaatcgc acttccaaaa atgacagaca acaaccgatc tgaagtaatc attgtttctg
     4741 gaactattgc aatgattaaa ggaaaaaaca agcttccgaa aagtacttta aaaaagggtt
     4801 ttttacctaa aaatagaaga gctagtacca acataacgat attcaacact aaaataacta
     4861 tagctcggtc aaatcctaaa acagcttcca gtaatattcc tagaccgctg acacctccag
     4921 cagcaatatg atgaggccct aaaaacatat tgatagcgac tcctaatatg aagagggcaa
     4981 aaataatctt aatgtatgtc catataaatt gtctcgtttc tttcatttat ccacttcctt
     5041 aattcattaa taatactctt atcttattat aacttacttt tcaccttaag ttaactttaa
     5101 ttaataaaaa aattaggcta gtctaaatta ttatgtttca ttcttctaga atatacttct
     5161 acgttaaaaa ctgttaaaaa acttttactt tagaaaattg gagaaattga tcgcttaaga
     5221 taaattcagg acactaaata gtacaggaag tagattaaaa cttttaaaag ttttaagtct
     5281 atctatttgg caagtttaaa aaataaaaat tcggtatcaa aaaactgtta ccgataacat
     5341 ttttgaaagc gttgtctttt gtttctctat cacttatagt gatgacgtca tattaaaaca
     5401 caaggaggaa atcaatggat acagctgcaa tttatcatcg accggaaagt gaatatgcat
     5461 ttctatatac gaatacaaga tttcgtattc ggcttcgtac taggaaaaat gatatcaaaa
     5521 aagtatatgt gctttgtgga gatccatata ccataacaac tgaaaaatgg tatcaaaaac
     5581 aacgaccaat gaaaaaatgt ctaagtacca atgttcatga ttattgggaa attgaagtga
     5641 cgagcgaaac aaggcgctta cagtatgcgt tccatgttgt tggggaagat aacacggact
     5701 gtttttacgg tgatcaagga atttttcctt atcgagaaaa tgtgattact gaaccaaatt
     5761 tttattttcg aataccttat tttcatcaaa tcgatcgatt cactattcca gaatgggtaa
     5821 aagaaacagt atggtatcaa atttttcccg aaagatttgc aaacggggac aaagcaaatg
     5881 accccgaaca cactttacct tggggaagta aagatccaga ccgagaagac ttcttcgggg
     5941 gagatttgca aggtgtgagg gatcatttgg attacttgac ggaccttggc gtcaatggca
     6001 tctatttttg tcccatattt aaagccacat ccaatcataa atacgatacg attgattatt
     6061 atgaggtgga tcccgctttt ggcgataaaa aacttttaaa aaacttgatt gatgaagcac
     6121 ataaaagagg gatacgtatc atgttcgatg ctgtattcaa tcatatgggt gtccattcac
     6181 cacagtggca agacgttctc aaaaacggag aaaaatcgat ctataaagac tggttccaca
     6241 tccgtttttt cccagtagat tcttatcaga tgactgactt accagaaact gctgaaaata
     6301 tcccatatga tacttttgct tttactccat tcatgccgaa actaaataca gcaaatccag
     6361 aagtgcaaaa atatttgctg gatatcgcaa cttattggat aaaagaattc gatattgatg
     6421 gatggcgtct tgatgttgct aatgaagtcg atcatcattt ttggaaaaaa ttcagagaag
     6481 cagttacaga aatcaaacca gacatctata tccttggaga gatttggcat tcctctcaag
     6541 cttggctgca aggggatgaa ttccatgcag tgatgaatta tgcattcaca gattcgatta
     6601 aagattattt tgcaaaaaag aaaatcacag cttcacaaat ggtcagtgga atgaatcatc
     6661 agcaaatgct ttacagagat caggtgaacg aaggaacatt caacttatta gattctcatg
     6721 atactgccag gatcttgacc ctttgccaag gtaacaaaga attgatgaag tctgtgatgg
     6781 cctttatgtt tcttcaaaaa gggtctcctt gtatctatta cgggacagaa atagggatga
     6841 ctggtgaaga tgacccggat tgccgcaaat gtatgatatg ggagaaggag gaacaagatc
     6901 tagagctatt cggttttata aaagaacttg tttctctaag gaaacagttg tctaagatta
     6961 tttctgaagg ttctactcag tggctaatag tatatgatcg tgaagataag ctctatttca
     7021 cacgggaact agagggacag atcatctatg tttactttaa tcagtcaaaa gaaccttggg
     7081 tagtagaaca ggaaaatgag gtgattctta gtcaaaattg tcagttgtta gaagacggga
     7141 aagcagagat acgacaatac ggatttttga tcatgtgttg aaaactgtta ccggtaacaa
     7201 caagaaagcg tttgcaaatg aagatttgtg cccattataa taagggtgta acagcacgtt
     7261 gaatacacag gaggaaatga agatgaaaaa aagaagtgtg aaacagttgg gtttagggtt
     7321 aatctcttta ggaatcttag gcggattagc ggcttgtggc aatggtaact cttcagcaga
     7381 aggggaagcc gatgaaggaa aaacgttaac agtttccgtt gattctggat ataaagatta
     7441 tataaacgaa ataaaaaaca ctttcgaaaa agaaaacgat gtgaaaatca agctagtaga
     7501 aaaggacatg ttcgatcagt tggaatcatt agcgttagat gggcctgctg gaaagggacc
     7561 tgacgttatg atggcagcat atgaccggat cggtgcgtta ggacagcaag gacatctggc
     7621 ggaagtaaaa ctgggaaatg aagcagctta cgatgaaaca gacaaagccc aagtgactta
     7681 tgatggaaaa atctacggag aacctgcagt aatcgagacc cttgttttgt actataacaa
     7741 agatttagtc gatacagcac catcaacgtt taaagatttg gagaatctat ccaaagacag
     7801 tcgttttgct tttgagtcag aagcaggaaa aaatacagga tttttagcta aatggactga
     7861 cttttattat tcctatggtt taattgcagg ttacggtggc tatgtatttg gtgatgatgg
     7921 cacaaatcct tcagatatcg gtttgaataa tgcaggtgct gtagaaggaa tctcttatgc
     7981 aacagattgg ttcaaaaatg tttggccaaa gggaatgcaa gacataaaaa gtgcaggaga
     8041 cttcgccagc cagcaattca tgtccaataa aactgcagca atcattgacg gtccatggca
     8101 agcgcaaaca tacaaagaaa acaatatcaa ttatggtgta gccaaaattc ctactctaaa
     8161 taatggacag ccttatcaac cgtttggcgg aggaaaagga tgggtagtca gcaattatgc
     8221 taaaaacaaa gacctctctc aaaaatggct tgattatgta acgaatcagg aaaatcaaga
     8281 aaaattcttt gaaatggtaa atgaaatccc tgcaaaccaa caagctaggg aaacagcaaa
     8341 ggctaaaaac gatgaattaa caacagctgt gattgaacaa tatgaaacag ctcaagcgat
     8401 gccaaacatc ccagaaatgg gcgaagtttg gacaggtgca gaaaacttga tgttcgatgc
     8461 agcatcaggt tcaaaaacac caaaagaatc cgcagatgaa gcagtaaaaa caatcagtga
     8521 agccatagaa caaaaatact gattaaaatg ataaccgtcc atttttataa aaaatggaac
     8581 aggtgcttca gataaaagtg gcaagagcga gatggaaaat tatcttgctc ttgttgccat
     8641 tatcttaaaa gcagtttgcg gtttagcaag tttagagggg gcattcagat gcagcaagat
     8701 aaaacaagca atatcaacga aaaaaaaatc acgctttgtt cacttattcc agggatgggg
     8761 cagtttgtaa atggccaagc ttttaaaggt atcgtttttt tcgccatatt cgtcctattc
     8821 attggtcaga tgcttctggg cggatttcat gcattggtag gattggttac tttgggaagt
     8881 ataccaatgg aagatcattc attatttatt ttgattgaag gcactttgca attcatcatt
     8941 acaatcattt tcttgatttt ttacggtttg aatcttttag acgcttatcg agtagcgaag
     9001 atgcgtcaag agggcaaaaa aatcaatcgg acgatgaagg aagtcataca taatataggt
     9061 gatgaaggtt ttccttatct attgacactt cccgcttatc ttctcatgat ttttacgatc
     9121 attttcccag tcctagttac attgttcact gcatttacta attatgactt caatcatatt
     9181 ccaccagcca gtttaattga ttgggtaggg gctaaaaact tttttagtat cttcttttta
     9241 agctcatatc gtaatacttt ttttgcagtc ttttcgtgga ccgtgatttg gactttatgt
     9301 gcaacaactt tgcaaatcac ccttggtatt ctcacagcgg ttgttgctca ccagaaattt
     9361 attaaattca aacgtatttt cggtatcatt ttcttattac catgggcggt cccagctttt
     9421 attactatca tgagtttttc gaatatattc aacgatagcg taggtgccat caatactcaa
     9481 gtgattcctt tcataaacca gcttcctttt gtagatatca gtgcaatctc ttggaaaacg
     9541 gacccgaact ggacgaaagt agcaattatc ttagtgcagg gctggttagg atttccctat
     9601 atctatgtga tggttacagg aatcttacaa tcgatttcag aagacttata tgaagcagca
     9661 aaaatcgacg gagcaaatgc atggcagcgc ttttcaaaca tcacgcttcc tgctgtcttc
     9721 ctagtggcag cgccaacatt tattacacag tatacgggga atttcaataa tttctccatg
     9781 atctatctgt ttaacaatgg tggtcccgga agcgtaggcg gaggagctgg ttctactgat
     9841 attcttattt cctggatcta taaacttacg actggaactt ctccgcagta ttctatggct
     9901 tcagcaatca cgttgattat ctccgtcatc gttatctgtg tgtcattgct ggtatttaaa
     9961 aagacaaatg cgttcaatat gggggattaa caatgaaaaa atttcattcg agtgctcgat
    10021 tccaaaaacg actttctcac ttttttactt acttttttct tttaatactg tcagtcatta
    10081 tcatctatcc gcttttgatc acagcaagta ctgccttcaa gtcaggaaat attgcagctt
    10141 ttagtttaga tctttcaagt gactggactt taggaaactt tactcggcta ttcagtgaaa
    10201 cactttacgg gacttggtat aaaaatacat tgatcatttc tgtcctaaca atgatcgtac
    10261 aagtgactgt agtaactttg gcgggctata cttatagtcg ctatcgtttt atcggccgca
    10321 aatcaagttt gatgttcttt ttagtgattc agatggtacc gactatggca gcattgactg
    10381 ccttttatgt catggctttc ttattagaag cgctcgataa gtactggttc ttgacaatga
    10441 tctatatagg cggtggaatt ccaatgaata cttggctgat gaaaggatac tttgacactg
    10501 taccaataga tttagatgaa tctgctaaac ttgatggggc agggcatttc aggatttttt
    10561 tccagattgt attaccgctt gtcaaaccga tgctcgccgt tcaagcatta tgggctttta
    10621 tgggaccttt tggggatttc atgttagcta agttcctgct tcgaacacct gaaaatcaga
    10681 ctgttgctgt cggcttacaa acatttattt ctgatgtgac aaaccaaaga gtctctcttt
    10741 ttgctgctgg ggcaattttg attgcactac cgatttgtct attattcttc tttttacaaa
    10801 agaactttgt taccggcctg acatctggcg gaacaaaagg ataggagcag agtatcatgc
    10861 aaacatttcc gttaaactat ttttccgcat tacgtacgcc aactcaagtg tttgcgggac
    10921 gcaaactatt atcatggcct aaatttttct tgatatttgt atttttagtt tccttgatgg
    10981 tcatgcctgt gactcttttt tatgccaatc agatccaagc gattccatta gaacaatttc
    11041 tatccgttca ttcgctgatc gatgaacaag gaacccaaaa attttctgaa cttgaattat
    11101 ctgaaactgg gttacaagca tcgcaacaaa cgatagctgt gacccctgaa attttggtag
    11161 gtgtgtcttt atctgagaaa caacaatccg atcatggaac ttttattgat tttgagaagg
    11221 aacaatgggt gatccaacaa aaggataaat ctggtatacg ccgctatacg atgaattata
    11281 gcccatcttt ccaaccagat tctgtacgta cgcccgaaga tttccaacga tttttagaaa
    11341 gagaatttta tgccagtaat cgtccaacaa tcattttatc ttatagttta agtcttggtc
    11401 ttgtcctatt tgtcatgacg agtctcattt tattcggggc ttcctttttc ttgtggatga
    11461 caagaaaaag ccaactttca tccattcata cattcaaaga gagtgcaaat ttgatgctga
    11521 atgttatggg aataggttcc atggcagcag cagttgtagg gtttatccac tttgacttta
    11581 tcttgatgct aagtgtccaa acaacgataa ctgtcttgct gcttttatgg gtttttgtca
    11641 aaacaagatt caaagataag cgtgtcgaat gacaagttta agcgatttat gcgacaatga
    11701 atgtgaaaaa aatgaaaaat aaagtagttt ttgaaaaatt tctgaaaaaa ttaaacttct
    11761 tagttgattc ttttcttttt tagtattaac gtaatagggt agttttttta aggaggaaaa
    11821 tcatgttaga gaaaacttta tacaatcaat tattttcacg ttctttctcg ctccctgtcg
    11881 aagtaaatta ttgggacggt acaacgaaac aatacggaga tacggacact cctccccaaa
    11941 tcaaaatcaa tatccatgaa gaaatcccaa tgaaagagat tacaagtaac gcttctttgg
    12001 cactaggaga agcctatatg gatcatcgaa tcgagatcga gggaagtatc caagcattga
    12061 tcaacgatgc ttatcagcaa gcaaacagct ttttacgagg aaaagattat ctaaaatggc
    12121 tgccaaagaa agaaaaacat acgaaacaaa aaaacaaaga agatatccat gcgcattatg
    12181 acttaggtaa cgacttttat aaactttggc tagatccaac tttgacttat tcttgtgctt
    12241 atttcaatac acctgaagat acgttggaac aagcacaaat caataaagtc catcatatct
    12301 tagacaaact ctttatcaaa gaaggcgaaa cgttgcttga tatcggttgt ggctggggaa
    12361 cattgatgtt cactgctacc aaagagtata atgtcaaggc aactgggatc acactaagtg
    12421 aagaacaata cgatttgatt accaaaagaa taaaagaaga acatttagaa gataaatgcc
    12481 gtgtattatt aatggattac cgcgaactaa aaggcgaaac gtttgatcat atcacaagtg
    12541 taggtatgtt cgaacatgta ggttctgaaa atcttgaagg ttatttcaaa gtggtaaaag
    12601 atttattgaa accaaaagga acagctttga tccatggaat cagccgacaa caaggcggtg
    12661 cgacaaatgc ttggatcaat aaatatattt tccctggcgg ttatgtccct ggtgttactg
    12721 aattagttga taatattaca aaaaacgatt tgcaactgat tgatttggaa agcttacgtc
    12781 gtgactacca attgacatta gaacattgga caaagaattt tcatcaagtc caagatcaag
    12841 tcacgaaaga aatgggtgat tccttctatc gaatgtggga tctatattta caagcttgtg
    12901 cagcttcatt tgaatcaagt aatatcgatg tgattcaata tttgcttgtt caacctggaa
    12961 acaatgacat cccaatgcat cgtgcataat tgaggcaaaa gtactgttta aagactattt
    13021 aaaaagaagc taagttttat gatgctccag aagtgaactt ttttgtctaa cttctaggat
    13081 tgtctctaaa gcttagtttc tttttcttta tattttcata ataaaagttt ggttctttaa
    13141 tttttaaaca tgacagaaaa ttttttcttc gttatacttg taatagaata ctattttata
    13201 acaaagggga tcgaatcaat gaaaaaaact gttatttata ctagtttatt tgcagctttg
    13261 tttttagctg cttgtcaatc aaataccaat caaggcacat ctgggaatac gtcttccagt
    13321 agcgaacagc gctcttcaca ggtatcggac tcctcaacaa aagcaagcac atcttcgtct
    13381 agccagacaa aaagttctag tgaagcaagt actcagtcag atatcaaagt gtctgcagct
    13441 cgtgcgatcg aattgttcca agataaatac ccagatactg caattactag tttggaatta
    13501 gatagtgatt ggggatctta cttctacaag atagaaggtg tcgatgatca aaaagaatac
    13561 gaagcaagaa ttgatgctca aaatgaaaaa atggagacag agaatccaga aactctagat
    13621 cgagatgaac aaaatggtca aaagaaaaaa gaagatggtc tggatgttga taaattgatc
    13681 acgattgagg aagcagcaaa aatcgccgtc gacaaagtag gaagcggtac ggcaacagat
    13741 tgggatttgg ataaagattt aggtactact tattgggaag tcaaagtaaa agacggcaat
    13801 caaagtacat cagtcaagat caatagccaa acaggcgaag tactgtcaac tgaacaagat
    13861 gattaagaat ttcttcggaa aacaagagtt gatttttctt ttagtcatga tacactagac
    13921 aaaataactt gtttgaagga gcgatttact tgagtttaga aacgaccttt gccaatcata
    13981 tctttgccaa tcctttgatg aatgcatctg gtgtccactg catgactacc caggaattag
    14041 atgaactggc tcattcagaa gcaggagcat ttatcactaa gagctgtacg atcaatgaac
    14101 gaaaaggaaa tcccgaacca cgctattttg atgttccttt agggagtatc aattctatgg
    14161 gacttccaaa cttaggtttt tcttattatc tagagtatgc tcttgcgtat gaaaaagtgc
    14221 aggaaaacca aaatcaaccg ttattttttt ccattgccgg gatgagtgtc caggaaaact
    14281 tggaaatgct tgagaaaata gaaaaaagtg ggtttaatgg gatcactgaa ttaaatttat
    14341 cttgtcccaa tgtgcctgga aaaccacaac tagcttacga ttttgaggcc acttatgaaa
    14401 cactgaaaga agtattcagc atcttttcta agccgctagg aatcaaattg cctccttatt
    14461 ttgattttgc tcattttgat cagatggctg atatcttgaa tcagtttcca ttgacctatg
    14521 tcaatgctat caacagtgtg ggcaatggtt tgtatatcga tacagaacaa gaagcagtag
    14581 tcatcaaacc aaaagaaggg ttcggcggca ttggcggaga gtatatcaag ccgactgctt
    14641 tggcgaatgt tcgcgctttt tatacacgtt tgaaaccaga aatccaaatc attggtacag
    14701 gtgggattcg gacaggacaa gatgcatttg aacatctgct atgtggcgca agcatgttac
    14761 agattggtac agagcttcat aaagaagggc cggaaatttt ttctagaatc ataaaagaat
    14821 taacgcagat tatgtcagaa aaaggatata cgtcaattga cgaatttaaa ggcaaattac
    14881 gcaccatttc atagcaaaga gacgaaggtc atgattgatc ttcgtctttt tttataaaaa
    14941 acactcgtct gttcattcct gtgcaagcgt actcattgta tgttagacga acttgtggga
    15001 aaataacaga ggcaaaaagg aggataatat gaatgatgca acagaattag caaaagagct
    15061 taaagaaaaa gaatttagtt ttcaagaact agttacggat atacagaaaa aaataaagaa
    15121 gcaaaatcat gaattgaatg cgtttgtcgc gcttgaacca ttcgagagta attcccacga
    15181 gctattgatt ccccagtcag aaaaagggcc attggctggt atcccatttc ctttaaaaat
    15241 gctcggtcaa gaaaaaaagg gatggctagc tacttcagga tctcgtttat ttgaaacaca
    15301 ccgagcttct catacatcta attatgtgcg gcaagcagaa gcgataggtc tagttccttt
    15361 tggacaaacc aatgcgccag agtttggttt caaaaatatt acagacccag tcatctatgg
    15421 cccagcaaga aacccttgga accttgaatg tacaccgggc ggatcaagtg gaggagctgc
    15481 tgctgcagtt tcatcaggaa tcgttccttt agctggtgct agtgatggcg gtggttctat
    15541 tagaataccc gcttcgtttt gcggattgat tgggctgaaa ccttcgcgag ggacgatgcc
    15601 agttggtcca tatgcttgga gaggatggca aggagctgct attgatttcg gcttgacagt
    15661 ttctatgaga gacacggagg ctttatttta tgggatgaga agtatccatt ccggtgcgcc
    15721 atatcaagta tcgccagttg agtggcaaac acatccaaga aaaaaacggt tgaagatagc
    15781 tttttgtgtt gattcaccga tccactcaca gattagtgaa gaggcagtac ttgctgtaaa
    15841 aaaagctgta gatttccttg gaaaagaagg gcatgatttg acagagattc cttacccact
    15901 agatggtcgt aaactgatca cgtcttatta tcagatgaat ggcgcagaaa cagcagcaat
    15961 gatccgctcg attgaaacag gcatccagcg agctgtcaga aaagaagaac ttgaacccat
    16021 ttcttggact ttgttccaat atggtcagaa gctctctgcc gctacttaca tcgattctct
    16081 gcatgtatgg gatgaagcag caattgtcat ggaaaaccta catcaagaat acgatctatt
    16141 cctttcacca acgactgcat ttaccgcccc taaaatcagc gaagatttgc aaagtgatgc
    16201 gataagagca cagatggaac acatcagtga ttgttctgaa gtagaaggtt tagacgttgt
    16261 ttcttccatg tttgaggaga gcttgaagat cacaccttat acacagttgg ctaatctgac
    16321 tggacaacca gcaatcagct tgcctactca tttgacaaaa gaaaacatgc ctctaggaat
    16381 ccaatttatg gctgccagag gaagagaaga tttgctattt caaatcggct atctatttga
    16441 agcaaatcat cagttccatt taccaaatcc atggaaatag cagaaacaag gagaagaaga
    16501 atgaagaaaa aaagattgtt tgctctaata actagtgcct tttttatttt aagcgcttgc
    16561 ggtacagctg ccgctaatca ggaagataac agctggagta atgtagaaaa aaagaaagaa
    16621 ttagtagtag cgacttctgg cacactgttt cccgcatctt attataatga tcaaaatgaa
    16681 ttagttggtt atgatgtaga tttggcaaaa gaggtggcta aacggttaaa tgtcaaaatc
    16741 tcctttaaag aatacaacgt ggatggacaa atcacttctg tttcaaaaag agaatcagat
    16801 tttgctgcga acgattttgg tatcacaaaa gaaagagaaa aaaaattctc cctttcagag
    16861 actttcaaat attcatttga cagtatgatc gtacgaaaaa aagatgattc aggaatccac
    16921 tcacttgaag atcttaaagg gaaaaaagca gctggcgaac ccaatactag ctatatgcgt
    16981 ttagcggaaa aacacggagc taaattagtc acatatgaca atgccacgaa tgatcagtat
    17041 ttaagcgatg tagcaaatgg tcgaacagat gttattctaa atgattatta tctgcagaaa
    17101 atggccgtat ctgctttacc agatatccct gtaaaaatac tggagaacgt ttatttcaat
    17161 gaaaacgaaa gtggtttttt attgaaagaa ggaaatgatg ctctgaaaaa gaaaatcgat
    17221 ggcgtattaa aagagatgaa agaagatggg acgacaaaga aaatatctga aaaatatttt
    17281 caaactgatg tttcagtcaa accgaaagaa acgatggctg agtcggtgag tgagtgatgt
    17341 actttcctct aattgatttt tccctcatgt ggacttcact tcctttcgta ctgcaaggct
    17401 tggtatacac attagggatt ggcttcgtgt cgtttctttt aggaaatttg gtagggttgc
    17461 ttttgacagt tttaggtctt ttggattggc tgcctctgaa tgtatttatt cgtttttatt
    17521 tatcgttctt tagaggcatt cccgcactag tcctgctgtt tctgttatat ttcgggttac
    17581 cttatcaatt aagtgcctta acggcttcag tcatctgctt tacgattacc agcagtgcat
    17641 ttattggtga aatctatcga ggatcactag caggcgtttc ttcaggtcag tgggacgctg
    17701 gtttagcttc tggtttttct ttctttgggg tattgaaata tatcgttttg ccgcaagctt
    17761 ttcgaatctc agtaccggca ctcagtaacg tagctatgga tctagtgaaa ggtacttcgt
    17821 tagcagcaac aatcacagtg ccagaaatat ttcaaaaagc aaagatcata ggcggtcgga
    17881 cattcgatta tttttctctc tatattttag ttgcactgat ttattgggtc atttgtatcg
    17941 ggatcgaaaa agtgcaacag tatttagaaa aacgttctat ccatcagtca atctgaaaaa
    18001 tagaaatggt gctagcgtgg ctggcaccat ttctattttt tgtttcttgt atattctgcc
    18061 tagtatttta aaaccatttc atgtaaaatg taaatcgaaa atatgttcgg aggtagaaaa
    18121 catgaagacc ccgctaacca tcgaaataga atcctcgtta taccaatatt gcatcgagca
    18181 aggcggcttg gttgtagaag aagtcacgat gcctgatgac caaggaattg tagatacgct
    18241 tagctgcttg acaaaatttg atggaagccg agaatggcga tgctatgagc tgaaagtgac
    18301 aaaagcagat tttcgctcta cagccaaact gtcatttgtt ggacattata attattttgt
    18361 tttaccaagt aaactatatg aagaagtaaa aactgaaatc cctacaggaa taggtgtttt
    18421 agtgtatcgt ccgtacacgg ttgaagagga gatgcctgcc tctggtacat ttctgattgc
    18481 gaaaaaagca gcaaagaaag agcttgctgt accggaagaa gctttgacaa accgcttcat
    18541 ggcttcttta ttcagggaag taagaaaagc aaagcaaatg gagcgaggcg taaaatattt
    18601 tccaaaagat caattgtaca aagaattgaa aagacgttca gaaaatcaag atccattttc
    18661 taacgaacga tattatgaac ggtttttaga ggaaatagct agtcaggcaa tcaatgagtt
    18721 gcaagaagaa gttatcgcgc ttcagcatga ttatgaatat ttgaggcaac aacagcagat
    18781 ccgtcggttg cctacagagc cattggagtg aaaaatatgt actatcctta tttaagagga
    18841 aaacaatttg acctattagc attaaaagaa gcactgtcgc gaggattgct ctccaataaa
    18901 atccaaccag tgatcgaacc agtacgtgat tccgctacgc ttaaaaatgt gatcgaatta
    18961 tttcaaaaaa agcaccatcc aatcgctgtg atccaaaatc cccaagtagg acaattcaaa
    19021 ttattcgatc agcatgtgca cagttggaca gtcaaagaaa atagctctgt cgtccctgca
    19081 cagatcttaa cgccagaaaa tctcagtgaa gtactggatt cacctccagc gtttcttgtt
    19141 ttcgatggac agcactaccc aaaagataca gaggtgtgga aacagttggc aggagttgat
    19201 tcgaaatttt tgataccaga tactagtcgc tttcgcatct ggctgcccga aaacaaaatt
    19261 gtgatccgtg actcttttca aacgagaaag catgttgaaa gttatgcaga taaaacagat
    19321 gactttttta gtgatgacta tctttttttc cacgcagacg gatatattgg attttctgat
    19381 ttcacgatcg aaggtagccg ttatttcgat aaagggttcc ctagccgagc gcttgctatc
    19441 catctaacgt atattgatgc ttacggcaat atacgcgtga aacattttgt ctctgacagt
    19501 aacgactctg ctaaagacca agcattgaag tttcttgaag caggagataa aatgaaaaaa
    19561 tggatcatgc gtcaccatca tcaactcttg attacttcag gaatgattga attattggct
    19621 ctttaccagc aacaaaaatt ccctggactg ggagtgttga aaaagtggtc acttatgcat
    19681 catttggaac ttattagtca cctgctagat catccaaaag attggcttaa atattattca
    19741 aaagttcagg aactatatga agtgatccaa tgattagata atgtaaatga aaaaggaata
    19801 gaaaagagga aactggatgt atattcggca aacaaggaaa gaagaagtag aagaagtggt
    19861 agaaatcatt aatgccgcag cggatttcat tgcttcgcaa ggctctcctc aatggcaaaa
    19921 cgggcagaaa ccaacaaaag aaacgatttt gaacgatatt gaaagaaaag aaagctatgt
    19981 attaatagtg gaagatcaaa ttgctggaac agctgcatta gtctcaggcg tggatcccgt
    20041 ttacacaaaa atagatggta gttggaaaga atcaactggt ccttatttat cgattcatcg
    20101 tgtcgcttta gcagaaagta ctcgaggaaa aaaactagca aaaccgttct tagaacattt
    20161 gttgacgatt gcagccagca aaaatatcca agatatccgt atcgatactt atccagctaa
    20221 tgaaccgatg gaaaagacca tctattctgc tggattcact tatcaaggga tgattgaatt
    20281 tccttttgaa cacggcgaaa gaaaagcata tcaaataatc atcaattgac tataaaatca
    20341 tctgagcaaa gataaagaca ttaacactac tgaaaaaaac aatcatatga tagccaagag
    20401 gttgtaacag aagtggccag cttcaaaaaa caagaaagaa tttccgaaaa tgcttctcaa
    20461 atttttgtgg aattttagcg tattttacga aatagctgct ttctgaaact cccttcatcg
    20521 agaggtcgtg acatagcttt tgtcacgatc tctcggctta tcctacgagt attattcgat
    20581 acatttatat caataatcct ttttttattt tatctgcagc ttcttggaac gctccatcgt
    20641 ttgacacgac taaaagtgag gggatagctt tcaaacgttt caactgtgct aaatcttcta
    20701 cataaaccgc cagtctggct gaaatctgtt cagatgaatc tccacgtttt ttcaggcgcg
    20761 attgcaatgt ttctttagag atcgtaataa agataggacg gactaccgtc ccgaaatact
    20821 catataaatg ccaaaaacca tttgctgtca aaacggcgta acaatttcct actgtcagtt
    20881 tctttttaat ttctgcttta ctggaaccat atttatgttg agcatattgg tcccactctg
    20941 caaactcatt tcccttgatc atctgattga atgtattgtc agaaacaaaa taataatcct
    21001 cttgatcttt ttccccaggt cttggtgatc gattcgtgta agtaatgatc ttttgttccg
    21061 gctgaaaaat agcttctgcg agtgaagttt ttccagaacc agaaggaccg ataaatacat
    21121 agcaataatt cattgtcatt tctcctttga tgattgaaca agtgaaaaag ctttggaaaa
    21181 tatttccaaa gcttttaaaa gtaactttgc ttttttgtat tttataccag caagccagtc
    21241 acaatagcac ttaaaaagct gactaaagtc gctgttagca aaattttcaa tccgtgtttt
    21301 gcgacaagat ttcctttttc ttcatttaat cccttcatcg caccagaaat gatcccgata
    21361 gaagagaagt tggcaaatga aacgaggaag acagatataa ttgctgttgt acgctcagta
    21421 aaatggaaat taccatttgc taattctgtc atagcaacaa attcatttgt aaccagttta
    21481 gtcgccatga tactaccggc atccactgct tctttccatg ggattccgct gatgaaggca
    21541 agaggggcaa agatgtaacc taggatctct tggaaagtga tgccgaatat cccgtggaag
    21601 atagcattga tcatggcaat caaagcaaca aaaccgataa gcatagcagc aaccgtgatc
    21661 gccacatgga aaccatcaag aatgtattct cccaacattt ggaaaaatgt ctgttctttg
    21721 ttttcttcaa tgatcagctc atcttctttt tcttctaata catagggatt tacaattgaa
    21781 gccagaatat aaccgccaaa taagttcaaa acaagggcag tgatcacata tttagaatcg
    21841 atcagtgcca tataagatcc gacgatcgac atagaaactg tagacatagc cgatacactc
    21901 atggtgaaca aacgtttctc agataggaag ggtaattcct tttttatgga aataaaaact
    21961 tccgattgtc ctaaaatagc agaagctact ccattataag attccaattt gcccatcccg
    22021 ttgattttac ttaatcctag accaacagct ttcataaata atggaagaat cttgatatag
    22081 cgtagaatac cgataatagc agaaataaat acaattggca tcaatacgga aagaaagaaa
    22141 ggtgcacttc ctttatttgc tacaccggca aaaacaaagt caacaccttg cccagcaaaa
    22201 gcaagaagat gatcaaacat ttttgccaat acagaaacaa ccgctgtacc aaaagttgta
    22261 cgtaataata cgaaaccaag aacaagctgt aaaacgaaca tcacaattag tggtttcaat
    22321 ttgattgctt ttttgttact gctgatcaaa aaagcaagcc ctaatgtgac aaataaacca
    22381 ataataccta ataaataact caaataatca ctcctattcc aaattccgtt ttattttacc
    22441 tgttttgcaa ataaaatact aatctttagt gaaattttca ttactttttt agagtgaaac
    22501 gcattcattt tccattagaa aataaagcga acaaaataaa aggtttaaaa agtgtaacgt
    22561 cttagtaaag tctataaaaa aacgaaacta tcgattaagc taatagtttc gttttcaaca
    22621 tttataagta aactttttct attggtaata tagattttcg gaagggtaga caggtgcgca
    22681 ggtaatatcg attcctagtt ttttcaatgt ttgttcatca tttttattga ccatcacagt
    22741 agagtgggct tgtgctccct caagttcagc tagtttatca taagcaactt gagcgattgg
    22801 attcgttact gcactgattg ataaagcgat caagacttca ttgatgctta gtgcatccaa
    22861 agaggaatga agtgtctttg atttcaatcc ttgtattgtt tcaagaacta atggtgacaa
    22921 taaaggaatg tcatctgcga tatgggctaa atgttttact gcatttaaga taactgccgc
    22981 tgacgcatcc atcaatgaac ttgtacgccc ggtaatgatg acttcatctg gtaattcgat
    23041 tgcaatcaca gcagaaggat cttttgtagg actttgcgct tgaatcttat ctgcatagtc
    23101 atgggcaggg actaccacgt ttcggtcttc aggacgtaaa ccgacttctt ccataatcag
    23161 tttgattcga ttaactgctt cttcgtcgat caatcctttt ttgaagtcgc attctgtttg
    23221 gaaataacga cggatgattt cttgtttaga ggcttcttgg acaacggtat catccacgat
    23281 cccaaatcct acacgattca cacccatgtc agtaggagat tgataaacag attctttacc
    23341 agtaattttt tcaataatac gtttgattac aggaaatgtc tcaacatccc gattatagtt
    23401 cacagctact ttattgtagg catcaaagtg gaaggaatcg atcatattga catcttttag
    23461 atcgactgtg gctgcttcat aagcaatgtt cagcggatgt ttcaacggaa cattccatac
    23521 tgggaaagtt tcgaacttgg agtaaccagc tgcatgtcct ttttggcttt catgatacag
    23581 ttggttcaag caagtagcga gctttccact tcctgggcca ggagctgtca ctacaacgat
    23641 tggtttagtt gtttcaatat actcattttt tccaaaacca tcttctgaga cgattttttc
    23701 tacgttgact ggatagtctt cgatttctga gtgtttatag accttgatgt ttcgtctttc
    23761 tagtttattg ataaagactt tcgtggcagg ctgtccacta tagcgagtga taacgacact
    23821 gttgattaat aagccataac cacgtaattc atcgattaac cgcaagatat ccatatcata
    23881 agtaatccca taatcaccac ggatcttatt acgttcaata tctccagcat agacgcaaat
    23941 cagtatttca gcttgatctt tcaatttttg cagcaatttg attttcgcat cttcttcaaa
    24001 tcctggaagt acacgtttcg catgcttgtc gtcaactaac ttcccaccaa attctaaata
    24061 taatttgtca tagtggttca ctcgttccaa aatatacgct gactgctctt caatatattt
    24121 ttctgaatca aaaccaattt ttttcactag gttccctcct taagtactaa agcatttttt
    24181 catttttttg aggattcgtc aactggaaga gcgaaattcc tcaaaaaaac aaagaaaatg
    24241 gtttaaacca acttgtctag atagttattc attggtatga tagtttttga taaggaaggt
    24301 gctacatgaa aaaaagacag aaaaagaaaa acgcatataa acactatatc cgttcgattt
    24361 ttaccggtta tgaaagaatg cttgaagatc ccgaattgga acaattgacg tttacttatc
    24421 taaacgaaga aacgcagcta actcgtgatg agcatcagcg cattcatttc acaacaagag
    24481 atctgcctag taaataaaaa ataagataaa ggtcatcgga ttcgattctg tcctatcaga
    24541 tggaaagact agttgatcga aaaaaaggct gtaccaaatt ttggtgcagc ctgttttatg
    24601 gagcattgcc cgctcttttt tataacaatt ttttacagaa aatggtacta ttgaagtatt
    24661 aataagtgaa aaacagatga gtaagaggag gcaagtagta tgaaagagcc agatacaaat
    24721 gcaaattatg agccagacga actagaggag acgaacgcgg atcaggatac aggacaagaa
    24781 tcgtcttctt tttacgatat caaagaaaaa gcaagcatga atctttccca attattagaa
    24841 gacttacagg cttttgaaaa agctgtccgc gaagaagata tccctgagat ctaccgttta
    24901 tacaatggcc gattgaatga agaattaaaa agaagctcaa atgaaaatca cgagatcgat
    24961 caattgctga tgcgtaagat ccatgatcgt tttttacagg aatttccttt tatggaacaa
    25021 gtagaaaaca tctcgccaac gatgagctat tacaaaatcg gcacttatta ccatgatcgg
    25081 cccacggtcg gtattgatgc aagtctgcca gaaatttttg ttttgcctaa gatcgatgaa
    25141 gagtgggaga aatattccca accggagtca acggactatg acaaaaaaat caatgagcta
    25201 gacgcaaagg tgatcactgc tcagacagaa attgaacgtt tagatgaaca aataaaagaa
    25261 atcaatcgac aaatgactga tttgaacgac aataaaggat tcttgaatcg taaaaaaatc
    25321 gaggaagaaa ttcaagaatt agagaagaag aagcaagtac tatctaatga aaaattaggc
    25381 tggcttcctt atattgagac gcctgaaaca atccagcagc aaaaagaagc attgaagcaa
    25441 gaagcaagag cagaccagct tcgtgcagcc atcgtagaaa aagaacaaag gcaaatcaga
    25501 cgctatttcg gtagcaaaga gggattcggt caagcaatcc atgaattctt gatgaattat
    25561 cttggcaatg agaatcctaa taatcaatct aatgaaggag gttccgagta tgaatgaaca
    25621 cgatgaagca gaatggacaa aaaatgaaga acaaacagaa gatcatgaag aaacgaacac
    25681 ttcattggaa gaacaaacaa gtaatcctct ggatgacaca gaagaaatcc ctatgctaga
    25741 ggaaacaaaa atacatgaaa aagaaaaagt aactccgacg aatacgaata ctgcagaaaa
    25801 cacccatgct tacgaaataa ctgaaaatcc cgggtattta gaaggaaaag agcaagatca
    25861 tcaagatatc gtcagtttga ttgaaacagc ggaagcagaa ttagcggatt tacgtatgag
    25921 aaaagatttg atcgaatcag attttccaca attattagaa tcatatgatc gttttatatt
    25981 gaatgaagaa ccaatctcca cgatcggaaa gacaagcctg atcgaatact tcacgtatga
    26041 attactgaaa ccgttgaatg atattggtct ggaacggtca aattcagctt atgacacatg
    26101 gaaaacaaga catttttcga tcaattatac gttgaatgga caaaacgaat tagtcttttc
    26161 ctttgtatta ccgaccatcg atcaacgata ccaagtggaa tcgatgagtc tcctaaacgt
    26221 atcaccagag acaatggaaa tcaatgtcca agatgaccgg gtgctttctt tgatccgaca
    26281 ctggtcagtg gatcgagtat tctctgcagg gcagatcacg atattcaatc acaaattgaa
    26341 tcaattatta gcccatgcaa gaacacttgg ttttaccgtt aatcagacat tactagacaa
    26401 tacgaagcca cttcgtttga atcttcagag cgaatttgaa ttgacgaatg aagtattgga
    26461 tgatattttt atcgtggcaa tgaaaaatcc atcctacgat atggaaaaga tcaacgaaac
    26521 tacttatcaa gtacgattag ataaaggaca gtctttaacg ataacaacaa acgaaaaaga
    26581 tcaaacagtc ttgtcgatct catctggaga ctacccacga tctgtcattg atttctttat
    26641 caattacgaa ttcttggtcc cattaatggt gagaaagtcc tgattggata agttggatta
    26701 ccagatgtca ttcagataat tctgttccaa aggacttgcg gcagttatcc agaataattg
    26761 tcacaagtct tttctgtatg tactaaatgg acgtgaataa cttgctgatg aaggagggat
    26821 ttcattagga atgtccacaa ataaaatagc acagcttagc ttattgtctg ctgcttgtgt
    26881 agcaggtagg atcgcttttc aatttattcc gaatttccag ccaatgactg ctattttttt
    26941 atttatagta ctttacttaa gcttaaaaga tgcgttaatt gtcatgagtc tttctattgc
    27001 gatcagcagt ttttattttg gtgttggacc atgggtcatc ggccaatgga tcagctatac
    27061 tgttgttctg agtttgtttt caatcgtctg cttgagaaaa acagtgcaaa ggaatctatg
    27121 gttaaaggga gtctgttttt ttctggcggg catggtttac ggaataggta tgaccgtttt
    27181 tgatacgctg ttatatcgtt tgcctcaacc ttggatctat taccttcaag gggtgtcgtt
    27241 tgatttgatg cacagtatag gcaatgttgt gttctttctt gtttttctgc cagtcgtcaa
    27301 acgtttttac aatcattcag gaggaaaaaa tgaaaaaaat aatttatagt ttgcttgcaa
    27361 tgagtgtcag tatactcatt ttgacaagtt gcagtacaac ctatacacaa tcggcttcca
    27421 accaaaagga ggaagtaaaa acatcgcaaa aagcaacaat cacgttacaa gaaaatggtc
    27481 aaaacttttc ggaaaaagaa gtggtcttca aaaaaggcga tgatttactg agtattttga
    27541 aacgaaattt tgaagtcaaa gaagataacg gcttcatcac ttcgcttgaa gggcactcac
    27601 aggatgagaa aaatcaactc tattggatgt ttactgtgga cgggaaaagt gctactactg
    27661 gtgccaaaga gatcaaattg aatgatggac aatcggtcat tttcaatttg tctaaactat
    27721 aagtttcata aaaaactgtt aaagggcgaa tattgccata attcagtgag ttcagttgat
    27781 gaaagaagga aaataacatg gaaaatttta aaaaaagcgg aatgttttcc gtaattgctg
    27841 ctctaggggc taatattcta gttgctatca gcaaatttgt cggctatgca atcagtgaca
    27901 gtgccgccat gctaaacgaa agcatccaca gtatcgttga ttgcagcaat cagattttgc
    27961 tgttattcgg tgataaacaa gccaataaag gacagagcga gttgcatcaa tttggtgaag
    28021 gacgagcaaa atactttttc agtacaatcg tcgcaatgat gcttttcttc ggcggtgggg
    28081 cacttggggt gatggaagct tttgaaaagt tgacgcatcc atcccatgaa gtgggtaatc
    28141 cgatcattgt tatagcaata ctgttatttg gtttggtaat cgaaggaagt tcgttacgcg
    28201 tggcaatgaa agaaatcaaa gaattgaata ctgaaaaact ttccacgatg cgctttttgc
    28261 gcgaaagtcg acacagtgaa atactgatta tttttacgga agacttgtgt gctgtaatcg
    28321 gtttggtctt ggctttagca ggaacaatat tgacttatgc aaccgggatt gctgcatttg
    28381 atgcgatcag cggattgctg atcggtttct tgctgatggg agccgccatt ttcctagcaa
    28441 aagaatttta tagtctgatc atcggtgaaa gcgtgacagc aagcgattta tcaaaaatca
    28501 agttagcttt tgaacgtcct gagatcagtc ggctgatcga tataaaaaca gttcatttaa
    28561 gtccaacgga gattttagtt gcagcaaaag cagatatcgt tggtaacaaa gagaatgaag
    28621 cttactcggt catcaatgat attgaaaaaa atatgcgtca gtctcttcct gacaagaaga
    28681 tgtatatata cattgaaaca gataaatatg acccaaatta ttctcgtaaa taaaacgttt
    28741 attcatgaat tgaagcaaaa atgagaaaaa tataatcttg tttttaaata aaacggctac
    28801 aatttagcga atttatgtta caatgagtcc gctgtttatt tgttgtaatt aaaggagata
    28861 ttttaatgaa caaaaagaaa agtgcgccat ggcttcaagc tttgcatgca gtgatgccac
    28921 tttgtataag ctatatacca gtaggattag cttgcggagt attgttgcaa aaagttggat
    28981 ttgatcctct cttatcagga ctgttatcga ttctggtctt ttccggtggc gcgcagtttt
    29041 tagttgcatc tatgcttacg acgcaagcat catttgcaac gacattattg atggttttct
    29101 ttttagaatt acgctataca ttattaggag caagtcttgc cggttttatg aaaaaagaaa
    29161 agcggacgtt tttggctgtc ttttctcaat cactgaatga tgaaaactat gcggtgaact
    29221 acttaaagtt ttcaactgac ccttcctgga ataaaagaaa ggctttatat gtcaattggt
    29281 tctcaatgac tgcatgggcc ggtagcaata tgatcggtaa ttttttcggc tcggtgattc
    29341 gagtagatgc tgaccttgtc cattttgctt tgacggccat gttcattttc atgtttatca
    29401 tgcagatgaa aagcgcacta ctgatcttta caggtttatt ctcaggcgta ttaggggtcg
    29461 tattcatggt attattccaa aatactttcg gattgattgc agcaacagtc attgcttcat
    29521 ttgccggatt tatgctggag aaggcattca aaaaagaaaa agctaagaaa ctaagagacc
    29581 gcggtaaaga tgtcaatgag ccgctcttca acttcccgga acaggaggcc aatcaccatg
    29641 actaaactat atttgctact tttagttgct tgtctgttca tcgtggcata tatcccgcgc
    29701 ttgttcccga tgctttattt tactcatcga aaagtgccat cctggttcag tgactggatg
    29761 aaatatgtac cggtggcatt atttgcggcg ttagctttta aagatgtttt cattactcat
    29821 gaacatctgg atattgcttg gaatatcaaa atagctgcaa tgattctagt agcaggcgtg
    29881 gcttacaaaa cacgttcgat ggcgttgtca gttttgacag gacttgcgtc tgtctttttg
    29941 ctgtctatgc tttaaactgt tttattttat taaaaacaga gattgcgaca taagttgttc
    30001 aaactgatct atccgaactg catttgcaac agtcaattct ggatgcaagt ttattcgtag
    30061 ggataaaaaa gattagtgtt ggcttatgat gcaagctctt ttttatttta ggaattagag
    30121 agggatttgt ccttctatga ttttttgcta taatagggaa gatgtttatt ttatgaaaga
    30181 atagttgagg gaatttaaat gaataaaaaa ttgatgcaag gaacattttg gctaaccttt
    30241 gctaatcttc tatgtaaagt tttaggggta gtctatttga ttccctggct aagtatgatg
    30301 gggaacaatc aagatggtat gcttgctacg acattgtata atgttggcta tcttccttat
    30361 ggattgttcc tgatgcttgg tacagtcgga tttccaaatg cgattgcaaa aaaagtagct
    30421 gtagccacaa aagaaggaga taacgctgct tgtcggctga tttttagaag tacgatcaat
    30481 atcatgtttg tcatcggtat cgcctctgct gcactgatgt atttatttgc tcctttacta
    30541 gccggaatca gtccgattgc taacgttaat aatgggatac tagctatcag aagtttatgc
    30601 ccatctttga ttgctatccc aattcttagt gcaatgagag gatatttcca aggaaaaaat
    30661 gatctgcggc cttatggaac ttctttgatt atcgaacagg ctgtgcgagt gatcgttatc
    30721 ttggctggta cttattactt gcgcgtattg actgacggaa ccatattaga agctgtattg
    30781 atcagtacag tcgcttcttt cttcggtggg ttagctgcga ttatccatat gtatatcgtc
    30841 ggacgcagaa aagacttctt cgaacttaaa gattttttga tttccagccg ttatttcgaa
    30901 agagaaaacc gatctgcctc tgtctctatc attcgggaaa cactaccgtt tatttttgtc
    30961 ggctcagtca ttactatcgt tcaaatgatc gaccaagtaa cgatgaaacc actgcttcac
    31021 tttttccgtc cagagatcgc agatcagcaa ctggaattct tattcagccg tgcttctgtc
    31081 aatccaaata aattgacatt gatcctgatc tccatggtag gaacagtagc tataagcagc
    31141 ttgccaatat taagcacgat gaagaaaaaa gatcggatac aaatcgaaaa aacagtagga
    31201 gatagttttt cgattgcgtt attgattctt cttccttcat tgactggaat gtctttatta
    31261 gctggaccac tatacacatt gttttttggc tatgatcctg aaagtgtcgg atatttccaa
    31321 atggctttgc tagcttcttt gtttttctct ttattcacga tcctatctac gatgcttcaa
    31381 tctttgaatc accatcgttt tgcgatccga ttaactgtag aagcaattat cctgaaagtc
    31441 atcttccaag taatcggatt aggattagtt ggcggatacg ggatgagctt atcaaatggc
    31501 ttagcattcg gtattgtctt tgttcgcggc tatcacttta tgtgcaaaga ataccgaata
    31561 gcacctttag caaagatcag caattttttc ttaaaaactt tccgctccac cctgattatg
    31621 cttgcagtat gttttgccgt tttctttttg ctgaatcagc gattgtcaat ggaatcaaaa
    31681 agctatgcaa tgatttattg tgtggctgta ggaagtattg gcggcttagt atttttattt
    31741 tctcaattcg gaaaaaatgg gtttcgaatg ttgaaaaatg ttaaacatca tagcagaagc
    31801 aaagaatagg ttaactaatc gttttttgct gtcacttgaa aaacggcaac tcgtatgatt
    31861 acgcttgtcg tttttctatt ttccaatttt agtttcatat ctaatcttac ttatgatata
    31921 gttataaggt ctggaaaaat tctttgaaac gaggaaatta aacacatgaa acttgcagta
    31981 gttacagata gttcggcata tctgccggaa cgtatcaaga accatcccga cttattcgtt
    32041 attccaatcc ctttgattat ggatgggaaa atttataacg aaggaatcga tatcgaagcg
    32101 gatgaatatt atggactttt aaaaaacagt aaagattttc ctactacttc acaacctgtc
    32161 gtaggggaag ttttgggttt atatgaggaa ttgaaagaga aagggtatga cacgatttta
    32221 agtatccatc tttcttcagg gatttctggc tttgtcaaca cattatttgc gatgaaagat
    32281 gacatcagcg gagtaacggt cattccttat gactctaaga tcactagtat gccgatggga
    32341 cacatggtag aagctgcctt agacttaaat gatgaaggtc agtcccttga tgaaatactt
    32401 gcacatatcg atcgaatccg agataatacc tatgcttatc tgattgtaga tgatttgaac
    32461 aatttagtac gaggaggacg tttgacaaat ggtgcagcgc tgattggcag cttattaaaa
    32521 atcaaaccga tcctgacatt ttctgaaggg aaaattgttt tattcgaaaa aatccgttca
    32581 agtaaaaaag catttgctcg agctgaagaa attattggta gaagaaataa cgaaatacaa
    32641 ccgccagtca aactttacgt gatacatgca aataatttag aagtagcgat tgcggagaaa
    32701 gagaaattgc agaaaaaata tccaaatgca gaaatcgaaa ttggtcattt cggaccagtc
    32761 attggtacac atttaggtga aaaagccatc ggcattgcca tttcagcgca ataattcctt
    32821 ttattcaaaa aacataccaa aaatat
//
LOCUS       DAIGSZ010000032        32194 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.032, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000032 DAIGSZ010000000
VERSION     DAIGSZ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32194
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.032"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(17..1120)
                     /locus_tag="NOB31_001515"
     CDS             complement(17..1120)
                     /locus_tag="NOB31_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCI0973727.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            complement(1342..1812)
                     /locus_tag="NOB31_001516"
     CDS             complement(1342..1812)
                     /locus_tag="NOB31_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HCI0973728.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            2069..3388
                     /locus_tag="NOB31_001517"
     CDS             2069..3388
                     /locus_tag="NOB31_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HCI0973729.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            3829..5469
                     /locus_tag="NOB31_001518"
     CDS             3829..5469
                     /locus_tag="NOB31_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HCI0973730.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            5623..6945
                     /locus_tag="NOB31_001519"
     CDS             5623..6945
                     /locus_tag="NOB31_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HCI0973731.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(7007..7438)
                     /locus_tag="NOB31_001520"
     CDS             complement(7007..7438)
                     /locus_tag="NOB31_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0973732.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(7502..8338)
                     /locus_tag="NOB31_001521"
     CDS             complement(7502..8338)
                     /locus_tag="NOB31_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCI0973733.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(8528..8830)
                     /locus_tag="NOB31_001522"
     CDS             complement(8528..8830)
                     /locus_tag="NOB31_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HCI0973734.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(8856..9287)
                     /gene="ruvX"
                     /locus_tag="NOB31_001523"
     CDS             complement(8856..9287)
                     /gene="ruvX"
                     /locus_tag="NOB31_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HCI0973735.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(9284..9550)
                     /locus_tag="NOB31_001524"
     CDS             complement(9284..9550)
                     /locus_tag="NOB31_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HCI0973736.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(9804..10529)
                     /locus_tag="NOB31_001525"
     CDS             complement(9804..10529)
                     /locus_tag="NOB31_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HCI0973737.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(10895..10965)
                     /locus_tag="NOB31_001526"
     tRNA            complement(10895..10965)
                     /locus_tag="NOB31_001526"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10931..10933),aa:Gly,seq:ccc)
     gene            11082..11834
                     /locus_tag="NOB31_001527"
     CDS             11082..11834
                     /locus_tag="NOB31_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCI0973738.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            11850..12329
                     /locus_tag="NOB31_001528"
     CDS             11850..12329
                     /locus_tag="NOB31_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCI0973739.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(12580..14160)
                     /locus_tag="NOB31_001529"
     CDS             complement(12580..14160)
                     /locus_tag="NOB31_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HCI0973740.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(14153..14896)
                     /locus_tag="NOB31_001530"
     CDS             complement(14153..14896)
                     /locus_tag="NOB31_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0973741.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(15072..15848)
                     /locus_tag="NOB31_001531"
     CDS             complement(15072..15848)
                     /locus_tag="NOB31_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0973742.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(16096..16932)
                     /locus_tag="NOB31_001532"
     CDS             complement(16096..16932)
                     /locus_tag="NOB31_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HCI0973743.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(16943..17872)
                     /locus_tag="NOB31_001533"
     CDS             complement(16943..17872)
                     /locus_tag="NOB31_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCI0973744.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            18064..18417
                     /locus_tag="NOB31_001534"
     CDS             18064..18417
                     /locus_tag="NOB31_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCI0973745.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(18491..19147)
                     /locus_tag="NOB31_001535"
     CDS             complement(18491..19147)
                     /locus_tag="NOB31_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCI0973746.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            19373..21307
                     /locus_tag="NOB31_001536"
     CDS             19373..21307
                     /locus_tag="NOB31_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI0973747.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(21393..22616)
                     /locus_tag="NOB31_001537"
     CDS             complement(21393..22616)
                     /locus_tag="NOB31_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI0973748.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(22610..24508)
                     /locus_tag="NOB31_001538"
     CDS             complement(22610..24508)
                     /locus_tag="NOB31_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HCI0973749.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(24502..25620)
                     /locus_tag="NOB31_001539"
     CDS             complement(24502..25620)
                     /locus_tag="NOB31_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCI0973750.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(25703..26536)
                     /locus_tag="NOB31_001540"
     CDS             complement(25703..26536)
                     /locus_tag="NOB31_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0973751.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(26529..27446)
                     /locus_tag="NOB31_001541"
     CDS             complement(26529..27446)
                     /locus_tag="NOB31_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0973752.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(27673..28797)
                     /locus_tag="NOB31_001542"
     CDS             complement(27673..28797)
                     /locus_tag="NOB31_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0973753.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            28980..29888
                     /locus_tag="NOB31_001543"
     CDS             28980..29888
                     /locus_tag="NOB31_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0973754.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            30029..31642
                     /locus_tag="NOB31_001544"
     CDS             30029..31642
                     /locus_tag="NOB31_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0973755.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         9944 a         6395 c         5489 g        10366 t
ORIGIN      
        1 tttcgtcatt tgtttcttaa ataaaacgat tctcacgcaa ttttattttt ttgatatctt
       61 ctactgtttg tgttccagct aattgcatga ccatttccaa ttctgtttta aagaaatcaa
      121 acacttgatg gactcctgta cttcctccta aagacaatcc ataaataacg ggtctgccaa
      181 tagcaacaag atctgcacct gatgcgattg ctttgaaaac atgctgtccg cgtcgtacac
      241 cgctgtcaaa cacgattggt acacgtttat ctactgcttc tgccacatat tgcaacgaat
      301 caaacgctgc tggaccacca tctagttgac ggccaccatg attagatacc cagattccgc
      361 cagcaccaga ttctaatgaa cgatagacat cttcttctga ctggacacct ttcacataga
      421 ctggcaaatc agaatgagca gcaataaatt ctacatcttt tggactaagc ttctgtttgg
      481 aagatttgta cacagcatcc atcgtttggc ctactcctga ttgataagcc tgaacgatcg
      541 gcattggcag tgggaaggta aacccatttc tgcggtctgt ttcacggttt ccgccaactg
      601 ttgcatccgc tgtcaatacg attgcttttg ctccattacg cttggccact tcaagaatat
      661 ccaaattgat cccatcatct ttgctcatat aaaattgaaa ccattgcggt gctttctccc
      721 cgcctgcttc tcttatctct tctaatgtac aagaagcgta agaacttgct gtatagatcg
      781 tcccaaaatc tgctacacct tttgcagaag ctttctccgc cttcacatga gctaagccat
      841 gagcagcaac tggtgccatg atgattggtg cagtcagcgt ttctttgtca aaatgtgtag
      901 ttgtatcggg taattctaca tctcttaata catgaggaat aatcagctga tgattgaatg
      961 cccgttcatt ttcttgataa gtaaataagt cgccagcacc actgctgatg taaccataac
     1021 caccagctgg aatcacttgt gaagcggcta tttctaaatc ttccatattg ataaaatcca
     1081 ctattccttc atttgtacct gcttgatacg ttttttccat ttcaatgcct tccctctata
     1141 aaaaattgaa tgaataatat gatagcgttt acacacttta tattactctt ccgtattgat
     1201 acaggcaaat aatctgttta catttcagtc attccagttg ttactactct gaaagaaatg
     1261 tttagaacac aaatagataa aaaacgatgg gattttgaca aaagtcgtgt caaagtccct
     1321 tttacgaaat actgtggatg cctattgaaa taagtgcggg ttgtttcttt gtatttcaat
     1381 cgtttcttgc cattcttcgt ttaattttgg attaccgttt tcttccttga acgcataagg
     1441 tcccaatcca aaaagctcag ttagtatttg attcacgatt ccatatagct cggtgtgatc
     1501 ggacacatga ttattgaaga tcatctcatt atcaccacgt ttgaatctca cattcgggct
     1561 ctcatgatga acctctatgc agttttcccc tttttttaac tgacggattt ctgaaaacat
     1621 ctcataaata tcttctccaa taaaaccttc agcaagcgcc agactgtcca caagaccgcc
     1681 tactgtcaac tcagagatta tcgctttgtt ggcaccaagc tttaatgtat agcttgttgc
     1741 ttctactacg ccgcatgcat tgcaaccacc ttctgatagt tcgctttttc tgatcaattg
     1801 aacttctttc attttctgtt cctcctctta gttttctact tatgtatttt ttatcacctg
     1861 acgtaagtgt attttatcgt cacgatcacg tgatttattc ttcagagatt ctacctgaat
     1921 aattcatact tttaattaaa accatgtgaa actgcctcac ggcagcttac aattactttt
     1981 tcatcttcac ccgttaagtg atgaaaaaag aacccctttc tgctatggtt aaagtgacta
     2041 aaccaaccaa aagaaaggag ttcttttcat gactagctta cacaaaaacc aagtaaaatt
     2101 caattcaaat atcactattt ctcatacagg tggtcaatta tcgagtgatt cgggtctcgt
     2161 cctagtgaaa gagctgatga acatctttgg tttttctgaa ctggctaagc aacacattca
     2221 cattgaagac gaacgagcgt attttactca tgacaactta tccatacttg agcagttcat
     2281 tatgcaatta attgctggtt actcagctga ttctgcagct aatctcctga gacaagatcc
     2341 tgtgtttaaa gctgttttag ataggaaaga actcgcttct caatcttcac tttcccgatt
     2401 tttagatcga ctatctgagg agaatatcca tgaacttcaa gctttgaacc aagaacttat
     2461 cgataaagca cgcctcatcc gtaatgatac ggaattaatc attgatttag attcgaccca
     2521 ttcagataca tttggtcacc aagaacaaac gaattataat acacactacc aaacctatgg
     2581 ttaccatcca ttggtagctt ttgacggatt gactggtgac ttcttaaaag ctgaactacg
     2641 ttcaggaaat caatatacat caaaaggcgt aaaggagttt ctcacacctt tattagagca
     2701 ctataatcac tctctaccaa acactgacat cttggttcgt ggagacagcg ggttcgctac
     2761 acctggtgtg tatgattcgt gtgaatcaaa aaagagtcat tatgttattc gactgaagaa
     2821 taatcgtaga ctaggtcaaa tagctgagaa atcagtactt tatggcgata atcaaaagtg
     2881 ggaagaacga gaagttcagt acttctcgac cacttatcaa gcacaatcct ggtcacaaag
     2941 tcgtcgcgtg tgtatacgct caacacgtga agcgggcgaa ctactctttc gacatgaatt
     3001 tatcgtgacg aatctatcag aaaatgtttc tcctgatacc atcttttcta tctatgccaa
     3061 acgtggcaca atggagaact tcattaaaga agcgaaagct ggcttttact ttgacaaaac
     3121 agacagtcct cgctttttgg agaatcatgt ccgaatgatg ctcagcttga tagcttacaa
     3181 cttagtcaac ttcttaagaa cgattggctt tgaagaagtc caaaagggaa tgaccattca
     3241 ttctattcga ttgaagtttc tgaaagttgc tgggaaatta gtccaaacgg gtagacgagt
     3301 ctatctcaaa ttatctagtt atcatgtgta tcagaatgaa ttctacaggg tctttgctcg
     3361 cctgaggcga gccagtcaat ggatctaatc caacaatcta acgatttttt tactgggaag
     3421 ttatccaggg agaagtatgc tcaaaatgcc ttacacccaa aatttattcc tcaatatttt
     3481 tgaacagtga atgtttgaag taacttttta gtcaaaatca gttgataggg atattagtga
     3541 tacatatttc aataaaatgt gccaaagaat taaagctatg aattattcag gattctattt
     3601 atctatctaa catatccttt attcttctac ttttctttct ttagcatata agagatacgc
     3661 atagtaatca agcaaggatt gttgatataa aaagaacaaa taccgctatt ttgatttctt
     3721 ttgactctat tactcatata aataaaattt attatacctg ctctttttga ctatatcctc
     3781 atctgactcc tatacttcgt ttgtattaaa acttaggagg aatcattcat gcttacaggg
     3841 ctaaacttat taaataatcc ttttctaaat aaaggaacag cttttacaaa agaagaacgg
     3901 gcaaaatacg gaatcactgg tatgcttcca agtactgtcc aaacattgga acaacaatct
     3961 gtccaagctt acggtcaata cttaagcaaa cagaccgatt tggaaaaacg tatcttctta
     4021 atgaatctat tcaatacgaa ccggacattg ttttataaat tgatgggcga acatttagtt
     4081 gaattcatgc ctgtcgttta tgatcctgtc gttgcggatt caatcgaaca atacaacgaa
     4141 attttcttga aaccacaaga tgctgtattt ctttcaatcg acgaaccaga aaatatcaaa
     4201 gcaagtttga aaaacgcagc agatggacgc gacattcgtt tgatcgttgt gacagatgca
     4261 gaaggaatct taggtatggg tgactggggt gtgaacggtg ttgacatcgc tatcggtaaa
     4321 ttgatggtct acactgccgc ggctggtatc aatcctgcac aagtcttgcc tgtatcaatc
     4381 gacgctggta ctaataacga agaattattg aataatccat tatacttagg gaatcgtcat
     4441 gctcgtgtag aaggcgaaac ttactacgaa ttcattgatc aattcgttca atcagctact
     4501 gaattattcc cagaattgtt attacattgg gaagattttg gacgaggaaa tgctgcaacg
     4561 atcttagaaa aatacgaaga taaaatcact actttcaatg atgatatcca aggcacagga
     4621 atcgttgtac tagctggtgt attaggtgga ttgaatatat caggtgagca attgaaagat
     4681 caaacgatct tgacatttgg tgctggtact gctggtgtag gtatcgcaaa catcctttta
     4741 gatgaaatga tccgtcaagg tgtacctgaa gaagaagcac gccaacattt ctatcaagta
     4801 gataaacagg gtttattgtt tgaagataca aaaggattga ctcctggtca aatcccattc
     4861 gctcgtaaac gctcagaatt cactaatgct gatgaattga caaacttaga agcagttgta
     4921 aaagcaatcc atccaacgat catgatcggt acttctaccc aacctggagc attcactgaa
     4981 gaaatcgtga aagaaatggc ggctcatacc ccacgtccaa tcatcatgcc tttgtctaat
     5041 ccaacaaaat tggcagaagc aaaagcaaaa gatttgattg aatggacgga cggaaaagct
     5101 ttagttggaa caggtatccc tgctgctgat gtggaatata acggtgtaac ttaccaaatc
     5161 ggtcaagcaa ataatgcgtt gatgtaccca ggtttagggc ttggtttgat tgcttcaaca
     5221 gctacacgag taaatgctga aatcatttct caagctagtc gagcattagg cggaatcgtt
     5281 gatgtaacaa aaccaggagc agctatcttg cctccagtag caaaaatcac tgaattctct
     5341 caaacgattg ctgaaactgt cgcaaaatca gttgttgcac aaaaattgaa tcgtgaagaa
     5401 atcacggata tcaaagaagc tgttgaatct gctaaatggg ttcctgaata taaatcttta
     5461 gaagattaag attgttatag taaaagaaca tacagaaact ttgtatgacg tctaaaaaga
     5521 aaaaagcgac tgcggcaaaa cagcagccag ccaactactg ctcttttgcc gcttctcttt
     5581 ggcttttttc atacgataca gaataagaaa ggatctgtaa aaatggcaca aaaaacaaca
     5641 accgcaactg cagttgagga aaagaaaaaa gaagggtttt ggtcaacaaa aattaccggc
     5701 gtaagtttgc ccctttattt gatcatggtc cttgtcctga tcattgcaat ggctttagga
     5761 aaattaccga cgaatatgat tggcccaatc gctgttttgg tcattttcgg taatttattt
     5821 cattttatcg gaacaaaaat ccctatagtc aaaagttatt taggtggtgg ctccgttttt
     5881 gcgatctttg cctctgccgc gattgctaca tttgggatct tacctgagta tgtagtaaaa
     5941 tccacagaaa actttgtcag caatatgggc tttttagact tttatattgc tgccttgatt
     6001 actggtagca tccttggtat gaaccgtaat ctattgatga aagcttctgt tcgttttatt
     6061 cccgttgcac ttatttcaat ggtcgtctcc ttttttgccg taggactcgt aggtatgctt
     6121 atcggaaatg gttttgcaaa ttccgtttta tatatctcat tgcccgcaat ggctggtggt
     6181 gttggagccg gagctgtacc tttatcaacg atttatgcaa atgttttagg tacggacgct
     6241 tcttctatca tttcccgcct gattcctgcg acagcaatga caaatgtcct agctatcatt
     6301 ggtgcagcgt tagttgctcg tgcgggacaa tcaatgccaa aattcaacgg taatggtaaa
     6361 ttaatggaaa aaggcgacct tggcgatgga aaacctagaa atgtaaaacc ttccattcca
     6421 caattaggtg tcggtttgat ggtatcattg actttcttca tcttaggaca aatctgtaac
     6481 tattttgttc ctaaagtcca tgcttacgca ttcatgatca ttatcgttgt tatctgtaaa
     6541 atcgcaaacc tattaccaga atattacgaa gatgcagcta tcatgttcaa caacttgatt
     6601 gtcaaaaact tgacagcagc tgttcttgcc ggtatcggta ttgcgttatt gaatctaaat
     6661 gtattggctt ctgctttgac atggcaattt gttgtcttat gtttgacaag tgttatcgcg
     6721 atttcagtag tttcaggatt tgtcggtcgt ttgtttggtt tatatccaat cgaatcaact
     6781 attactgctg gcttatgcaa caactcgatg ggtggtacag gaaatgtagc tgtcttatct
     6841 gcagctaatc ggatggaact tattgctttt gctcaaatgg gcaatcggct tggtggtgcc
     6901 atcgttttga tcatctcagg tttcttgatg caattacttt cttagtcaaa aaaaatacct
     6961 gatcatcaag tatcggcttg atgaccaggt attttttgat aaaaatttac aggattttca
     7021 aaaatctttt ttgcatttta tcggaatgat aaccgatgcg ttcataaaat cggtgtgctt
     7081 ctactctgta ttctgcagaa ttaagtctta ttgctgatat tcctcgtctt ttcgcttctt
     7141 ctacgccagt catcaaggcc tttccgattc ctcttttttc agcatgttta gacacagcaa
     7201 gtgccataat attgaacatc ggatcgctga aaatcgattc ataggactcc gcttgtacat
     7261 agccagctgc ttttttagaa gtaggatctt catagaccaa gaaaaaattt ttttctggct
     7321 ccttcaacag tttcttcatt tgtctcaccg taacggttaa tggtacatca tatcctaatt
     7381 gttccgcatt gatttctcgt agtgcttctg catctcctaa acgcatttcc cgcaacatcc
     7441 aaatcaccag ccaattttta tttttttaaa tgaatttttt tatcacagta tactcctttt
     7501 ttcacttaaa aaaagacttt tcagtgattt tgacttgctt gaatccagat ccttctaatg
     7561 tttgcaagat gacgaaagca ttgtaaagat tgatcaaaag aaccacgatg acaatcgctt
     7621 gaaaaataaa ggtcactttt tttggagaca aaaccctgct aaatcttgct ccccacaaac
     7681 ctccaataac agcagcgggg ataacataaa acaacataga taaatcaaag cgcataaagc
     7741 tacttgttaa agcaatcgtt accaattttg ccagttgaga aaagaaaatc gtagatagag
     7801 aatatagtgt tgcttctttt attggcaatg caaacatcag catcaacaaa gaaacattga
     7861 ctggtccacc accaatacct aaaaaactag ctaaaaagcc cagaaccccc ccacatataa
     7921 ggtaccaagt ccatgacgtc aaatgaaatt ttggctgatg atgcttggtg tagaagaacg
     7981 caaaaaccaa ggtcaatacc gtcaaaaaaa tttggatcag ctgcacatgc ttctcgtttt
     8041 caaataactg taaaaaaact tcgaatacaa tgttgccgac tactcctcca acaacagctc
     8101 cactagatac ccaaccgaca atctgccaat tcagtgattt cccgcttgat acttgtcgca
     8161 cagtcgaaac aatggacatc gtgaataccg caactgttga gtaaaaagaa atccctgcaa
     8221 cagaatgggc gccgataaga tcaagaatcg gtttgatcaa cacgcctcca cccatcccgg
     8281 aaatagcgcc aactgtgttc gccagaacga tcaccacaaa ataaatcaga ccaatcatct
     8341 tgtatttcct ttctcttgtt tatatctttt agcgattgtt actcttttct tttattatac
     8401 agtaaaagaa acaaacgagg cttcgaaagc ttttctactt tttaaggaaa tttagtgcta
     8461 aacgaaaaaa ccgggctcta cttttcagag agtccagctt ttcttacacc ttatcgattc
     8521 ttttgttcta ttcttcttcc gccatgaatg tattgaatac ttcttcgatc atatcccatt
     8581 ctgcgtctgt ttcgatttgt tctaactcgc cttctgttcc atcttcgttt tcgatgtatg
     8641 cataagcttg taattctaca tcttcatctt ctgaaacacc agctggatat aaaagaacat
     8701 agttacgtcc aaattcttct tgtccgtcaa ctgttagcaa gatttcgtat aatgtttcat
     8761 ttccttggtc atccaccaat gtgatgtgtt cgtgtccttc gtgttcgtgg gaatggttat
     8821 gttctgtcat aagattacct cttttctttt tattattaaa ataattgctt acctgagccg
     8881 tctaaataat tttgtaaaat catcacagct gctaatttat cgatgacttt ttttcgtttc
     8941 gctcttgaag tatttgcctg ctctactagc atacgttctg cctgaacagt ggttagtcgt
     9001 tcatcttgat aatcaaccgg caaggagaat agttctttga tcttctctcc atatgacatg
     9061 gaagcttctg cccttggtcc gatggaattg ttcatattct taggtaatcc aactacaaaa
     9121 cggtctactt cgtactgcgc cactaattcc ttcaaccgat caaaaccaaa ctcttcttct
     9181 gcctcattga ttcgaatgat ttctactcct tgagctgtcc agccaaaggg atcgctcaca
     9241 gcaacgccta ctgtcttaga accgacatcc aagcccatta ctctcataaa ttcactccat
     9301 gatttgagag gtagtctttg acaattactt ccatgatttc atcgcgttcg tgacggcgaa
     9361 tcaaatttcg tgcatcacga taacgaggaa tgtaggccgg gtctccagaa agcaagtagc
     9421 cgacaatctg attgattgga ttgtagcctt tttcttccaa agcccgataa acaatcgcta
     9481 atgtttcgct cacttctttt ttgcgactat cgtcaaaacc aaaacgtacg gtttcatctg
     9541 taaaacccat gattctacac ctctttcccg caaggtaatt ccagcttacc ttctacaccc
     9601 ttattttact cgaagaaagg gaaaactaca aacaaatatt ccaaacttct gaataaatta
     9661 agaaacacga tttgtctgat ttttcctttt ttctgtggct ttttcaaaag ccctctttcc
     9721 ataaagtata cgctatattt ctttgaaagt atgtttttac acaatttttt cataaagttc
     9781 ataaaaaatt cgaattgctg ctactaattt ttcgttttcg ttgcttgccc tgtctcataa
     9841 ttgatggtgt agccatcttg aacattgtag ataaagacat tgaattcaat ttttttgtct
     9901 tcaatgcttt ctgcttccaa ctgcacacct cttgctacca gttcatttcc ctcgaaatga
     9961 ggagtgacac gatagcgtac atgatgattt gtttccttga tatatgccgc aatatcattt
    10021 tcgtgggcaa gcatgtacgg agcattcaac gaacgtgtcc ctgtcattaa gtttttaatg
    10081 ttattatttt gaccagtcaa ctggaaacca atcaaatggc tgcggttgta taaccattgt
    10141 ccgtcactta atttcttttg tttccaacct gtcggatcaa tatacaaagg ttctctcttt
    10201 tcagtaggaa acaagtcttt tcccaacatc gcattggctt gtcctactct gttcaatttg
    10261 tctatatttg aatagctttc ccatgtccct ttggaaagac taagatcctc ttttgtaaac
    10321 tccggctgat tcccattgat ttctatttct tgatgttttc catcatattc tggcacatcc
    10381 gctacttgag aagcttgcgg tgtggaatca aaaatggttg taatttgttg gaagatatct
    10441 gaatcttttt gtgtggtgga aataccgagt gcccctgcaa tcacagcagc gacgatcccc
    10501 acgatcgcct tggttgtttt tttgctcatt tctttactcc tttactaaca gttccctaaa
    10561 tcttaacata tgttccccta taaataaata ctggaaagaa atagaaacag taaaaaaata
    10621 aaaccagttt ttagacggct taagaataca aaaaaagaga cggattcatc gtctctactc
    10681 aatcacaaaa cactatttac aaggtattta ttatcattca aaaaattttt cttaatactc
    10741 aaaactaaac ggcttctgta cgacctcttg gtaaacagtg ttcaaaagct tgcatctgcg
    10801 gtaataagtc caaccaagtc aaaaacataa gaagcttttt tgcttgacta ttcttattac
    10861 ttgatgcagg gcagcttttt cacagcctct tttaagcggg tgacgggaat cgaacccgcg
    10921 acatcagctt gggaagctgg gattttacca ctaaactaca cccgcgatac aaaaacagta
    10981 tacgcctctt tcactccttc ctcaagtttt tttattcttt acgcttccga tatgttttgt
    11041 agtaaaataa aactaatcaa tcaattattg gagaagatgc tatgacggga aaagaattag
    11101 atctgttgct ggacacttgt ttactcgctg ggaaaatcat gatggaaagc aatgcggaga
    11161 tgtatcgggt agaagatacg atgagtcgaa ttgctttagc ttctggaaat ttccgtttgg
    11221 tcagctatgt cactcaaacc ggtctcttta ttggtcttga tcgtacctcg accatccgaa
    11281 tggaacaaat taccaaccgt tcgattaatt tagaaaaagt agtaaaagta aatgatcttt
    11341 cacgtaaata tgttgcttca gagctaacat tagaagaact ttactgcgaa ctgcaagcaa
    11401 tcgaccgaga ccgttctttc tttcctgtct ggttgcaaat cgttagcgcg gcagtgatca
    11461 gtggaacaat tatggtgtta tttggcggaa agatgaccga tttacctgtg actttagtca
    11521 ttggaggatt gggatacgca gcttatctat atagtttgaa attttttaga atcaaatttt
    11581 tatcggaatt tttatcttct ttattgattg gcatagccgc tatctacagc gtacgttttg
    11641 gcttaggaag caatcaggat ctaatcatta tcggatgtgt gatgccttta gttcctggag
    11701 ttcaaattac gaacgctatc cgtgatttgc tagctggaca ttatgtctca ggagtttctc
    11761 gcggaacaga agcgatgatg actgctacga tgatcggttt tgcgattgct tttattttcc
    11821 agctttttta ttaggaaagg aacacaagta tggggacgat atttattcag ttttctttta
    11881 gttttttagc gactgcggca tttgccgtta ttacaaatgt acctaggcgt tcattgattt
    11941 gttgtggtct ttctggtgct tttggctgga tgatctactg gatctgtgtt caaataggcg
    12001 gatctgctgc ttttggttca ttgcttggtt ctttaggagt agcattcatc agcgatcttt
    12061 tctctaaacg tttgaaaatg cccgtaacga ttttcaatat tcccgggatg gttcctctag
    12121 tccctggtgg tttagcttat caagcggttc gaaatctcgt tactgaatcc tatcgagaag
    12181 cggctcatta tgcggtccaa gcaattatga ttgctggagc aatcgcttta ggtcttgtat
    12241 tatcagaagt ctttaaccat aacatccgta atttcaaagt aaagcgtgac gcaatcatga
    12301 tgaaacgaaa aaaacggctt tttaaataaa cgaagtgtaa caaagaaaag gttgtgaaag
    12361 agacgttcag ccttgagcga tgacaaaata tctcacaaac attgcgacaa gtaaccgcag
    12421 gagcaataag aagtaattat gagtattaaa aaaagttttg taaaaatagc ttctcacatt
    12481 tttacataaa attgacttaa tactgagaaa ctgacttttg aacaccctct atctgtaaaa
    12541 aaggggctgc gacatgattt ttgtcacggc ccctcttctt tattcaaatt ttttccaaaa
    12601 cgttcgttga taataaacga tccatagagc ggaaagtatt agaactaaac cgatcacagg
    12661 aatattcact aaccaaaatg gataaaacaa agccaacatt ccgtataaga cgataagaat
    12721 aatactgatg atcaatgaac ccatcatagt tgcgactaaa cccaaacttc ctgaacctct
    12781 gttaaataat tggttaatat tggtccagtt cagcagcagc aaccgataat ctctagcgaa
    12841 ataacgtagt gacaataagt agcagccgaa taaagaacca aatagcaagc tagggataaa
    12901 aaacaaaggc agctgaaaag acagtccgct taataatgcg atcccaccag ttaaaaaact
    12961 ctgcaatatc catccgaatc tgaacttttc ttttaaatat tggttcatag agattggcaa
    13021 agaacggata aacagaaaat tttcttgatc caaagaaata agattgctga taaaagaagt
    13081 ctgattaact gttaagaaag ccaatgcgat ccctaccagg aaaacaacac cgattaactt
    13141 attatctaaa tcagttaatt ttatttcgcc tcctagggca aaagcaagaa taaaaatgat
    13201 tggagttaac aaggaagaag aaagaacttg cataatcaaa ttaggttctt ttactaattg
    13261 agcattgtaa ctaaataaaa gctgatgcac attttggttc tttttatggg ttctttttat
    13321 tttgaactca ctgtttgaat cagtcagttg ctctgtaagc tttggtacta tcagctgttt
    13381 tacagcaagg aaaaatccca gagccgtgat agctagtatt ccccaaccca ataaaccttg
    13441 ttgagaaagt ggctgactgg cagcatcata gaatggcaat aatatcgaaa tcggatgccg
    13501 atctgttaac tcattttcaa tagtccccgt ttgatgattc atccacatga ttccagcaaa
    13561 tgcgatcagc atcgagctgc caagcaagat actagaaact gtttttctat gttttttaaa
    13621 cactgctgtt cgagccaaac caaaaacaat caaactagcc agacaaaaaa gaataatcaa
    13681 aaatagagaa aacaaaagga ttgagataat gatagtaagc aaaatcccta gatcagctcg
    13741 ccatccggtt aaaataaaca tgactagaag cggaaaaaca aaaggaatga tggtcaaagc
    13801 aactaccaaa atctttgctg aaaaaacctg ttcttgtcca aaaggcagag gcaaaaatac
    13861 ttgcaggtca tttccttcaa aaaagatatt ataaatgact gatatacttt gagttaaacc
    13921 taacatacca aaaagtgcca cgtaataagt aaagaaacct ggcaatttaa caaagttcat
    13981 agcaaacata gcaaatccgt aaatcagtaa aaaaatcagc cctgaaaaaa gattttgaga
    14041 caaaagatag atagttaatc gctttccctt ttttcctttc tctcttgctt tattcgtgag
    14101 ctgtggatta acatataaaa gattaactcg aattaattct aataattgtc gcttatacat
    14161 acggtccatc tcctgtcgct tgccttccag ccattttcaa ataaatcttt tctagcgttt
    14221 catcaggtga gccattcaat aattcactaa ctgccccctg ataaatcaat tcacctttct
    14281 tcaaaatagc cagtttatcg cataactgtt gtgcggtatc caatacatgt gtagaaaaaa
    14341 tgactgtttt tccttttgcg gcatgagcct tcatcatttc tttcaaatca aatgctgctt
    14401 gaggatcaag tccttgcaaa ggttcatcca atacccaaat atctggatct ggcagcaacg
    14461 tgccgatcaa aatcgttttt tgacgcattc catgtgaaaa acttgcgatt gtttcatttt
    14521 gatgactata catatcaaaa agcgctgtca attctgctaa acgcttttct tttttttgtg
    14581 tgtctaattc ataggcagct gaaatcaagt cccaatattc tccagccgtc aattgtaaaa
    14641 aaatatctgg ggaatcaggc acataaccga ttttttgttt gatactcaat cgattttccg
    14701 tcaatttcat tccatctact aaaatcgttc ccgatgatgg ttcaataata ctaactaaac
    14761 ttttaatcgt agttgatttt ccggcaccat tatgtcctaa aaatccaaaa atttcccctt
    14821 gtcttatcga gagagacaag tcttttaatg cttgtttttt cccgtaactt ttacttacat
    14881 tgatgaattc aatcatttct gtactccttt tgtttgttat tactttttat tgtacccttc
    14941 gttattggtg gagtaaatgt caaaaagagt gcataacaaa aaaggataga aacgactagg
    15001 ctgctacttg ggttgttctc ttctacagga aaacactctt ctaacaggta agatatgagt
    15061 ctttgttttc tttaaaatga ttcattttct atcttttctt gcataaaatt ctttagttta
    15121 tcaatacttc tctttcccat ctctagttgt tctccatttg caaatgttac tatttcgttt
    15181 actctgctaa tagatgtaat gttttcagta ttaatgatat aagcttttaa atctttacat
    15241 aaatactcat attcgagtga ttttttatat tttttaattg tgccgtttac gagaatctct
    15301 tcatctttca atactaggcc tattttattt ttataacctg gcatgctcat tagataaagg
    15361 atttcatcgt aatggatata gtgatcgcta ttaccataac ggacagttgt ccaccttttt
    15421 ttcgtagcat gttgaacagg atagttttct ttttctttca ataagtaact ttggatgctt
    15481 tttttatttt tttcataagt gaattctttt atcaaataac cactaggcgt aatctttcga
    15541 ttaataacag ttattgcttt attcggatga gacgttagat aaacaatttt acacttttca
    15601 ttcttttctc taagcatttc gcctagttcg ataccgctat aataggcgtt caaatcgatg
    15661 tctaggaaaa aaatatctga ggaatagatt tcattatttt taatgaattc aacaaattgt
    15721 ataacgttca atccctgaac gatctcaaat ttccaaggac ttaataaaat tctggattct
    15781 tccaaaattt ctactagcat tttttcaaaa accaaactat catccaaaat aaatatacgc
    15841 gttaccataa aaagtacctc cactcgatat tttactatca aaatcatttc atacaacttt
    15901 tcaacataca tgttaggaat aaattgtaat tctcttcaca atcttttcca acacctttga
    15961 aaccgatatc aaatactttc aggatgctgc ttctaaaata aatatcaaac aaatgaatac
    16021 atcatgcaaa aaaagccaga caaccgacgt ccttgcgtgt cagctgtctg agctatgttt
    16081 atttattttg ttcttttaaa aagaacgata cacatactga tttttcggag cagagacttt
    16141 ctcagcgttt gtaacaacta cagatgggat ttcacgcttg aatggttgat aatagtctga
    16201 ttggatggtt ccttctattt tataccattc atcattttta accgttactc cttccggcat
    16261 atgcgtcaac aaaccaaaga ctcctgaatc tgccacacaa tggataatgc cgaatcggaa
    16321 caagaagata tctgtattgc tatcgttcgg tgtttggtaa acaaatcctt catagctgat
    16381 ttttttgcca atgaattcgc tagggtaatt ataaattagc tccataactt ctaaatagtt
    16441 ttcatctgtg atcttgatag tttgcttatc cccatacttt tctttcaact cattcatttg
    16501 gtctaagtag tctgatttgt tgaaataaat actggtatcc ggctttaagt attgtgtctg
    16561 catctccgga tcccctactg attctttact tactgggaaa ttaaatcctt tggcttctac
    16621 gatcgtagtg tcgagactaa ctgttggaaa caacgtcccc acgattactg gcaaagctag
    16681 cagtacataa gcgattccac gttgataagg ttttgacaac ccatggtcat gatcgtgctc
    16741 gtgtgccttt tcttctgctt ttccgttttt gacccacaaa tacagctgaa ctaaagccaa
    16801 aagagcagat aaaatcattg aaagaatagc taagtagcga taatggacat tgatatattg
    16861 atcgagtttg ccagaaactt gcaagtacat catcaattcg aaatacccag ataaaatcaa
    16921 aaaccgcagc atattttccc tcctaaataa ataatgtgaa tccaataacg ctaagggcaa
    16981 tcagtccgat cagcgataaa ataaagcgtc ctgtaaaata tcgtttcatc atcagtagat
    17041 ttttgatatc gaccattggg ccaaagacca aaaaggcagc tacaggtgct gtgccgaaca
    17101 gacttaacaa agaagatcct ataaacgcat ctgcttctga gcaaagagac atcgtaaagg
    17161 ccaataacag catgatgata atggctaaaa tctttgttga gccgagcgtt agcataattc
    17221 tagttggtaa ataagtctgc atcgcagctg cgattaatcc gccaatgatc aaataacgac
    17281 ctgtatcaaa aaattcgtcg attgaatgtg tcaacacatg cccagtttga tggatcagct
    17341 gattttttgg ttcattcttc tcactttgtt cttcttcatg gacatgatga tggtgatttt
    17401 ctgctacttt agacgtgatt ttttctttca atacagcgtc tttttgaaaa taggcaagcc
    17461 agacaccaat cacaagggca acaaaaaagc tgcctatcac ccgccagctt gccatctgcc
    17521 aagaattgcc aaatgcgata aaagtggaaa aaatcacgat tggattgatg atcggagcag
    17581 tcagcataaa agcaaacgct gtgtgaactg gtacgccttt tttaacaaat tgatgaacga
    17641 tcggtacgat gccgcattca catgaaggaa agaaaaatcc taagatcgaa ccagtaaaaa
    17701 tagagaagat acgattttca ggaagccatc tcttcacacg ttctggggtc aaaaatactt
    17761 gtaaggcgcc tgagataaga cagcctaata atacgaaagg taatgcttca ataacgatcg
    17821 ataagaaaat cgtactcatc tgcaaaaccg aatttggaat aaaagaaaac atgagtttcc
    17881 tcctttttat ttctagttca ttcgctttgc aaatatacgc ttttattcaa aaaaaacaag
    17941 ttgctctgta aatttttaca caactcttat tttttaccaa agcacttcaa ttgacttttt
    18001 ctgttattcc cattaaatta aggtctcata catatcactt ctatcataaa agggagaata
    18061 aaaatgaaac aaaccactaa cttgactgaa gttcaagaca tactgcaaca gtcatccgtt
    18121 gccgtcattt atctttcgat gcctaattgc agtgtttgtc acgctgttcg tccacgacta
    18181 gaggaacttc tcacacatta tgatattccg gcacttcatt tggatgcatt tgaaacacca
    18241 gaagtagcta gtaaatttga agtgctgact gcgccagttg tcctgatttt tcatcaagga
    18301 aaagaagtct ttcggcaagc acggttcatc gactttaaaa aaatccgtta tctactagat
    18361 gaactgacag cagaagatga ttccctttct tatgaagaaa tcttccgaac aaaataatcg
    18421 ttgtccaaac agaaaaaagc gattgaacaa gtgaaagttt tgccttcatt tgttcaatcg
    18481 ctttttattt ttattctgct gtattttcgg aatgcgcatt tgcgtcagaa tgcaagaaat
    18541 agatcaaggt ttgcaattca ttcgtcaaat caacattttg gatcaataca tctgacggag
    18601 cattcaatcg agcagcggta aagttcaaga ttcctttgat tcctgcttcc gttaactgat
    18661 tgactacttc ttgtgctctt tcagcgggta tcgttaaaat tgctacttcg atttgttgga
    18721 tcttgatttg ttctgacata tcttccattg gataaacggg gataccgtct acgatgcgcc
    18781 caacgatttc ctcattcaca tcaaaagcac aactgatacg tatgctatta ctttgatgga
    18841 atttgtattt tagtaaagca cttcccaagt tccctacacc gatcagcgca acatttgtca
    18901 attgatcgtc gtttaatgtc tttgcaaaaa agtgcataag atcttctaca tcataaccat
    18961 acccacgttt tcctaattcg ccaaaataag aaaaatctcg acggatcgtt gcactatcta
    19021 cttgaacggc ttcacttaat tcagttgaag acactttttt ctttccagca ttatttaaaa
    19081 tccttaaata gcgataatac aaaggcagtc ttttagctgt cgcctttgga ataatatgat
    19141 ctttcacgaa atgacctcca cgtattgtct aattacatct ttgatttctc catcatagca
    19201 gtatttatag gaaaaaatca attccattgc tcagatattg tgaaatttta ttctttattc
    19261 atttatttat catttctgca aatctcgcag tataatggaa tttatggtag actactaatt
    19321 gaaaaatagt tttttatttg aggagaattc acaaagtaga aaagaggatt ccatgatatt
    19381 attacaagcc aatcagattg ctcgccattt tggtgcagaa gtcttatttg aaaacataca
    19441 tttagaaatc agtacaggcg ctcgtgtcgc tttagttggc agaaatggcg ctggaaaatc
    19501 gactttatta aagatcattg ctggaattga agcacctgat gaaggaaaga tcgctaaaaa
    19561 taaaacagcg actctcggat acctcgctca ggacacagga cttgattcca atgaaacagt
    19621 ttggaacgag atgctgaaag cttttgaaca agttagacaa atggaagagc ggatgcgcga
    19681 gctagagatt ttcattagcg aaggtacgcc agacacacct gcttatagtt cttatttaaa
    19741 agaatacgac cggctgcaac acgatttttc agatcgaaac ggctatggtt atgaaaatga
    19801 aattcgttcc gtattgcatg ggtttaaatt cgattcttca ttttatgatc agaaaatcga
    19861 tactttatca ggcggacagc gcacacgttt agctttagct cgcatgcttt tgcaacaccc
    19921 tgacattttg attctagacg aaccaacgaa ccatttagat atcgagacac tttcctggct
    19981 tgagaattat ctgcaaagct atactggtgc attattgatt gtttcccatg accgttattt
    20041 tttagataaa gtagtcaatg aagtctatga attaagcaga agaaaaatgc gccattacaa
    20101 aggtaactat tcgaaatatc tagatttgaa agcagaacag ttagcaagtg aatggaaggc
    20161 ttatgaaaag cagcaaacag aaatccataa attagaagac ttcgttgctc ggaaccttgt
    20221 tcgcgcctct accacaaaac gagcgcaaag ccgcagaaag acattagaaa aaatggaccg
    20281 gctggatcgt cctcaagggg atgaaaaaca agcaaacttt ctattcagta tagaaaagcc
    20341 ttctggaaat gtagtcttgc aaatcgaaga tgccgctatc ggatatgata atgtcacctt
    20401 atctgaacca atcaatctag atatccgtcg tcaagaagcg attgctctag taggtccgaa
    20461 tggtatcggg aaatcgacgt tgctgaaatc aatcattcac cagatccctt ttatccgtgg
    20521 aaaagaaacg ctagggacaa atgtcaccat cggctattac gatcaaggtc aagctgatct
    20581 gcatacaaac aagacgatcc tagcagaatt gtgggatgag catcctacca ctccagaaaa
    20641 agagatccga agtgctttag gtgctttctt attttctggc gaagatgtag aaaaaccaat
    20701 ccctctgcta agtggcggtg aaaaagcacg ggttgcttta gccaagttag cgatgaacaa
    20761 agaaaatttt ttgattttgg atgaaccaac aaaccattta gatattgaca acaaagaagt
    20821 attagaaaat gcattgatcg attatgacgg cacactgctt tttgtttccc atgaccgata
    20881 tttcatcaat cggatcgcga caaaagtcgt cgaactctct gaaaatggca gcaaagtcta
    20941 tctaggagac tatgattatt atttagagaa aaagcaggaa gaagaagaaa tcgccgaatt
    21001 gttggcacaa gatgagccag aatctgctcc tgctcccacg aacaaatctg attattacca
    21061 aagcaaagaa cagcaaaagc ttatccgtag ccttcaacga aaaattactc aggttgaaga
    21121 agaaatggcg cggatcgatg aatggatcga tcagttggaa caagaaatgg tcgcgccaga
    21181 aaacctggaa gatcacgtaa aactcaatga gctgaaccaa gatttagaag ctgctagaca
    21241 agatcaagaa acaaaattga cggaatggga agaactaagc ttggaattag aagaatatga
    21301 aaattaacga aaaaaccaaa acagaaacca ttcatgctgt tttggttttt ctttttttat
    21361 tttatcaaac aaaaattcca tatttacctt tttcaccaat aagaagacca attactagtc
    21421 attctcacta aagcttctaa ataatagtaa tcaccccaaa tacaaggtgt atttacccca
    21481 ttatttttgg gcttattata aacagactgt gttaaaaagc catcttcttc ttccgttgta
    21541 gcatatcttt ctttcaattg tcgcataatt ttccaaacag cagactggta taagttcttt
    21601 tctgttttgt ctaatagacc tgattctatt aattctaata atccacaaac catgatcacc
    21661 atactagatg tatctttttc ttctctgcta gaatcatcaa agatcaaatc ccaataacaa
    21721 atggtatctt ctggcaaccg attcataaaa taattggcta atattttgct taaatcaaaa
    21781 tatttttgtt ctttcaaata acgataactt aatgcaaaac cgtaaatccc ccatgcttgg
    21841 cctctagccc aacaggaatt atcactataa ccttgatgcg tacttccata tcttggtttt
    21901 ccatctttga catccatata aaatgtatga taagttgaac catcttctct tactaaataa
    21961 tctgctgcat tttgaatatg agcctgagca gcttttttat atttttgatt tccagtttct
    22021 tcactcgccc aatacaataa tggaagattc atgcaacaat ccatgatcat tctaccttgt
    22081 tgtgaaggat cactaggatc tccccaagct tgtataactc ctgccttctc ccaaaaacgc
    22141 tgaagtaatg tttctgcagc atcaattgaa gcttccttca tttttcgatt tcccgttatt
    22201 ttataatctg ctacggttga taaagaatac aaaaaaccaa gatcgtgatg attagtgata
    22261 atttgacagt caatcctgtg gataaaatct atatctgctt tttcagctgt ttgttgaaat
    22321 aaaggatcac ccgtcttctc aaataacaac caattaattc ctgtccaaaa tccttctgtc
    22381 caaccaatat tgtctcttaa tggataacgt ccttttatag gacactcgct tgggaattga
    22441 tactgactgt tactgatacg tttgattaac ctctccgtgt gtctgcgaca acgctcgatc
    22501 tcattattcc attctttttc cattaattct ttataacatt catttatcca tttttctgga
    22561 tgtattatct cttcaaacat cactttatca agcatttccc caccagcctt tagcataatt
    22621 ttagtctttt tttattgttt ttattttgga tagttagccc ggttgtccca tcaaaatcaa
    22681 ttttgggacg attgttccat acttctaaac tataatcccg atcttgatga gcaaccactc
    22741 ctgttccgag ccaatgggtt ccttttccaa atgtaccctc taatccagga ataaaagtgt
    22801 tttcccatgt catcaagttt gtattgggca aacccataat agctgtggat tttcgtttaa
    22861 tagtatcgtc acttaaacag ataatacctg aaaagccagc ttcactcacc ctatagtttt
    22921 ccttgtcttc ttctatgatt attccttctt tctcaggaga acattcaata gcaaaccctg
    22981 tctcatatag aacatattct gtatctaatt ctactttgtg tacgcgaatc tgccagcctt
    23041 caaaaggaat aagccaagtt ctgatttttg cctgtaaagt aggttcccat gtagaggcaa
    23101 gtacctcttt cttacataca atgtctcgta cattatttcg aacgatgaac tgtccatagg
    23161 ttttgatgct ctcattctta aaactggtcg tgatatatgt gtccgctcgc tgaatcccta
    23221 gcattgaatc cattgccatt tctgctttca attgattcgc tcgcggtatc gaaaaaccaa
    23281 attgactaga ataagcaaat tttaaatatt tttcattggt caatgtatgg aaatttggcc
    23341 ctaattgtcc cgcattcaaa aaaaatgtat gtccattatc atgttgtatg agcaaattgg
    23401 cttctgaaag aagtttagtt ccttcacgaa taggcatagg catttcttta gccgtccaat
    23461 actcatggtc ttcaggtagc gccaacaata aaaaaatctt attcagccat aatggagata
    23521 acgtactatt atagggttca gtcaatgtca attgagggta ggtataacca atattcagga
    23581 tacctttttc atcaaatatt tctttttgca tccaccatct tatattccga ttgactaacc
    23641 ccttgatttc acctaattta aaaggcaaaa gatcggccca caacatagct gaccaaaagc
    23701 ttgaaactgc aaaacgataa atcatgcttc gaccaaaagg cacatttgca ccatcttccg
    23761 caaaaaaatg aatatagtct ctagaaaaat caatagctcg gttcttatat atctggctaa
    23821 tgggcttttc tggttctagt acgctataaa tcaaaccata ataatgaaat gcaaaaggat
    23881 tataataatc ttggcgacct cttgaactgt ctcgatacca gccattttga agataacaat
    23941 tttctatatt atcaaatgct tctttcagtg ctgattcttt aactggataa ccaaattttt
    24001 ggataattgt tccgacaatt atcttaaaaa attgccaatt accatctgca cattcatatt
    24061 caaaaatttg cgagaaccaa tgaataatct ggcttttttc tcctgtatct aattttttcc
    24121 ataataattg ttcatgatga tataacgcta ataacattgc gggcatttct accatacgct
    24181 ggtctctttc atgtatttct ccccaataat cgggatggga aggatctgtt ccagctttta
    24241 ttcctgatag aattaatttc aaccatcgtt catctaattg gtcaattgcg ggccccgctc
    24301 cccataaaac ccgagagaat ccttccattc ctgcaatttt atttccatat cctacccctt
    24361 gatgtatata atcaatttgt gcgccacttg ctcgataaaa cggctggagt ggttgattta
    24421 tctttttaaa taagtcaaag taatcctgtc tggtccttaa tagtggtact ggatgtttca
    24481 ttgtattttc tcctcttttt actaccaaat agctaattcc gactgttcta atcgaagtaa
    24541 gccttcaata aaaaaataat cagaatagat cagtggcaca ttataagtca gttctctatg
    24601 gtatgcttct gctccgcctc caatgatccc atcttcatcc atattccaat ttgcatagtg
    24661 cttttctgtc ttttggagta tattgatagc agcttcatga tacatttttg atcgtacaga
    24721 ggaaacatat cctgctaatt ccagaagacc gcatgcagcg catactccag cactggtatc
    24781 aatattcgaa tcttttacag caaaatcaat gagaggaata taaccagttt tttcgatttt
    24841 ctgaataaaa tttactgcta tcttttctgc tatagctaga tagtacggat tttttgtgta
    24901 acgataactt aacgcgaatc catataaagc ccatgcattt cctctgctcc aacaagaatt
    24961 ctcattgtat ccttgcccgc caagtaaccg aatatatttc cctgattctg catcaaattc
    25021 tgcgatatgc ccggttgatc catctttcct cactagatac ttagctgttg tatctgcatg
    25081 ctgccgagca attttagaga acctcggatc accagtttcc ctcgaagccc aatacagtaa
    25141 tggtaaattc atcatactat caataatcat ccaaccaggt ttatggtcat tccatgctac
    25201 taaatagttc cctgaaatat tatagcgtcc agcaagtacc gtagctgcat gtaaccctag
    25261 ttgtcgacta tgtttgtttt gagactgttg ataatgtgca atagccgatg gtaagaataa
    25321 aaaacctaca tcatgatgaa cgtctgaaaa atggtacagg gcagattcta ataattgttc
    25381 ttgttgtatt gctgcctctt tgaacttttc tcgttttgtc ttgtgaaaga gctgccataa
    25441 aataccactc caaaaaccat tggtccacca gtcgattcct ctgtccttta ttacgtctgt
    25501 atattttccg ttgtaagaaa tatatggaat tttattcccc attctgtcta attccgcatc
    25561 tatcttttca gaagctacat tcaaaatttt tcttgaccat tccttcgtct gttcattcat
    25621 ggatatcccg ccattctttt aatttttatg aatgtggagt tgctcctaga acgaactaga
    25681 tggttaacat tcgttatttt ttttacttat ttgcagctcc aatgtcattc tccttaaatt
    25741 tagactgcgc ccacacataa atcaagacca ttgggatcac tgaagttgct aaaattagca
    25801 taattgcgcc ataattaatt ggctcacctg tactagaaac cgtcatattt ttgataatta
    25861 agggaaccgt atatttatct ttatctgaaa gcatgactaa tggaaataga tattgattcc
    25921 aacttcccat aaagataagt aaaccactag taataatcgt aggtgataaa atcggtacag
    25981 cgattttcgt aaaaatcacc cactcattgg caccatcgat tctggcagcc tccatcagtg
    26041 ctgtaggaaa ttgactgcta tattgtcgca tcataaacac tgaagttgta ctggcaatcg
    26101 aagggatgat cacacctgca taagtattcg ataatcctaa acgactcata atgtaaaata
    26161 aaggaatcaa tgtggtaaaa aaaggcacca tcctagatag cataactgta ttgaacaaca
    26221 gtttattccc cataaaacga tactttgcta atgcataacc cgccattgta gaactggctg
    26281 tagctgaaac tgtactgatt acagcaataa caatcgaatt ccaaataatc aagggataat
    26341 tatatctcgc catgatggct tgccagtttt ttaatagcat atccccaaac ttgaaattga
    26401 ttccgccact taaaatttct tgattacttt gcgttgaagc tacaatcata tataaatatg
    26461 gcatcaaaaa tattaaggca ccaaacacaa taatgacgta cgtaaaaatt ctgctttgta
    26521 tcttttgttt agtcattttt atcacctccg aatttaaatt gaatagccga taatataaca
    26581 gatacaaaca ccatcgtcca ggcaatagca gaggcttttc caaaatcaac catttcaaaa
    26641 cttgttttat ataaattgac tcctacgacc aaagctgaat tttctggtcc attggaagtc
    26701 ccaaagaata tatttgggat attgaaatta cccaagccat tgatagtggc taaaactgtg
    26761 gccattaaaa tgattggctt tagcatgggg atcgttaata aaaagaattg ccgaaatttc
    26821 gatgctccat ctatttcagc actttcgtat atctctttag aaatcccttg aagaccagct
    26881 aaaaataaaa tagtgttata tcctacacta agccaaatca tcgtgatgat cattgatatt
    26941 cgtatccaaa aaggatttgt taaccactgt acaccgttaa ttcctagcgc attcaaaaat
    27001 ccattgaata acccagtcgg attgaaaaaa gtcatgaata cggaagctac agccaccgtt
    27061 gatgtaatgg ttggaatata atagacagtt ctaaaaaatc cttttccttt taactgtgct
    27121 gaattcaata aaacagcaaa gtaaatagct aatagcatcg ttattggaat tgatcctgcc
    27181 atgataatca aaacattcgt gtaagattta ataaacaatg gatctcggaa gatagctaga
    27241 taattgtcaa atccaacaaa ttcaaatgag tagccaattt tcataaaact aaaagcaaac
    27301 gagataatga tgggaatcaa aatcgtcaca ataaagaaaa taacaaaagg tgtgaccaat
    27361 ccataagcac tttttttatg agacgtatct gttgcttttt tcttgctgtt ctttattgtc
    27421 ttgcttggta acgaagattg catcatcgtt aagtcctcct aatatttttt aatcaccagt
    27481 taattttacg ccgtacttat gagcaaaatt ttctgcttct tttagatatg aattttcaaa
    27541 atcacctgtt tgccaatagt tatatgcagc ggtagtcaaa taagacgtag catctgaata
    27601 agtggctggt aaaacagtat ttgatgtatt ttcattgatt ttattcaata gttcatagta
    27661 tttttgtcct ccttagtagt caaacttttt ctcagctgct tctgtttgat aggccaatga
    27721 gttagatgta gccacgccca gctccagtgc gttggctaag cattcttcat ctgtcagcat
    27781 aaatgtaaga aattgttgtg ccacttgtgg atttttggca tctttaggga cataaaaact
    27841 tgatcctcct gatactgcac cttttcctgg attttctttt gaaaaaggaa tcagtggagc
    27901 catgcgccat ttgtcagatg catcaggaaa attcaaagac atattcgtag cataccagcc
    27961 gccagcaaca aacattgcag attcttgaaa tgctttctca gcatcttgtg caccgtagaa
    28021 atgtacaata tctgagtcga tcatttcttt gattaacttt gcagcatgtt tcgcttcttt
    28081 agtattcaga cggatatttc cttcttcatc aagcaaagat tgattctgct gggctagcat
    28141 gttgataaac aattcttggt ccccagattc tggcaaggca attccaaaac taccagtttt
    28201 ttcttttaat gcttttgcca cctggatata ttcttcccaa gaactgattt cttcaaaatc
    28261 tacacctatt tcagcaaatt tttttggttg ataataacaa agtgctgggg taaaatcact
    28321 agcccaagga ataatcgttt cattactcgt ttgttgacgc aaaatattca atttttgatc
    28381 ataaaactga tcgccatatt tgtcataaaa tccatattca tcagcactat aaaaagcatc
    28441 ttgaaatttt tccagcacac ctgctgctga agtgtctgcc atggagataa tatccggcat
    28501 atcttcgtgt gttaccaatt ttggggtgat catttgtact gttgctgttc ccgaagctac
    28561 attcacaatt tttaagtcaa tatttgctcc agttttgcgg ttatagattt ttgcagcatt
    28621 ttcaacatag tttgtcagtt tgccgtttgc gacatatact tctaatgtag tggctttttt
    28681 tatcattgga tctgcgatgt ttgctgttac ttcttcgtta gtttttccac atgcacttaa
    28741 gctgaataat agggtaatgt ttagcaaagc tatcaccaat ttgtatcttt ttttcatgtc
    28801 tatcccttct ttcttttcaa gttcttatat aaaacgcttt cacttatgta tattaacgga
    28861 attagtaaca caaatattta tataaaaaaa tattttactt gtcgttttgg cttttcattt
    28921 ttgttataat agtcattaat tataaataga aagcttttta tataaaaaga gaaaggaaag
    28981 tggttctttt gttaacaaac aaccaatcct ccaatcttgt caaaaaaaca ctaacctatt
    29041 ccatagatac ccatcttcat ttatctgctg ctccctattt tcgactacta ataaatgaaa
    29101 gcgctaattt atatgctgaa tttgcacata aatctataga actagataat ccttcccttt
    29161 tattcattga taaacagcaa gaagtccaaa tcttttctac tcaaaaggaa acacaaactt
    29221 ttatcattat ccagttttat tttgatgagc aattattagc acatattacg ggacaatctt
    29281 tttctataga tcaagaaata acatctatca ttacttttct gaaaaatgaa cagttcaaaa
    29341 ttgattatct aaaacatagt aagccagcta tttcctatga tcaggaaatc aattcttttt
    29401 tcatactatg ccaacagatg agcattcatt tgctttcctt attagttact tattgtctgc
    29461 aaaaaattca attgtcttcc ttaccaaggc attatcaaca ggaacttgct ttattgacaa
    29521 taccttcaaa tgagaaagtc attcctaaaa aaaagcatat tctttattca gatgaattag
    29581 ttgatccaat catacgatat ttagaagaac atctttcaga aaattttttg cttgaacaat
    29641 tagcccaaat tttttttatc agtccagcca gcttaaaaaa acattttaga aaagtgaatg
    29701 gaaaaagtgt tattagctat tttaaagaac taaaaatgga aaaagcaaaa cgtctcgtgc
    29761 tagaaaatga attaacctat acagaaattg cagatatatt aggatttcat tcgatccatc
    29821 atttttcttc agcttttaaa aaatatacag ggttatcccc ttcaaagtat tatctatcct
    29881 taaaatagaa aaaaattttt aggttttatc cacaaattat ttctctatat tttctgtcta
    29941 ttcaaaataa acaataattt tccggcacaa ttatttgctg ttttttacca taacatagta
    30001 cgatcaacgt agaaaaggag atgtttttat gaaagttgtt gtcattggcg gtgtagctgg
    30061 cggtccttca tttgccactc gtttccgtcg attgaatgaa gcgcacgaaa tcattatcta
    30121 tgaacgcgga gaaaatattt cttatgcaag ttgtgctttg ccttattatt taggaggtgt
    30181 gatcactgac cgtgactcgc tgatcgaacg tacaccagaa atattgaaaa caaaaaacaa
    30241 catcgatgtc tttactaaac acgaagtaac agcaatcgat ccttctacta agcgattaac
    30301 agttaaagac ctatccacaa atgaagaaat aaaaacagat tacgataagt tgatcatctc
    30361 ttctggtgct agaccagatt atccggatat tcccggagtt tttgaagcag aaaacggctt
    30421 tgtcctccgt agtgtgacgg atgcggatcg aatcaaatcg ttccttgaag aaaaaaatcc
    30481 acaacatgtc gtcattcttg gtgcaggtgt tatgggtctg gaattagctg agaatttcaa
    30541 gcatcgcggc ttagacgtga ctttaatcga tcaattgcca caagtcgctt tcccttatga
    30601 tccagaaatt gctaatttag tttatgacaa attgctgaaa gaaggattag ccgttcattt
    30661 agaaacaaga gttactgaga tccgtgataa aggtcgagaa atagtattat cagatggctc
    30721 cgtcctttct gctgatatgc taatttttgc tgttggtgtt tctccgaaga atgaagtggt
    30781 gaaagcaacc ggcatacaat tatcagatac aggtcagatc attgttgatg accagttaca
    30841 aaccaatctg ccggacatct atgcgattgg cgatattatc gaaacgacta gtgtagtgac
    30901 tggtcagccg atccaaagta tgctttccag tgcggccaat cgtcaaggac atatgctggc
    30961 agatatttta aatggtacgc ctatgcgcta tcgcggatat attggtgcag gtgtcgcaaa
    31021 aatctttgat catacagcaa gttatgcggg aatgacagaa catgaattaa aagcatcagg
    31081 cataacaaat tataaaactg tttttatcac tccctttgac catgcctatt tctatccaga
    31141 agctacaaga ttaaatctaa agctgatttt tgatgcagat agcggtcgta ttttaggtgg
    31201 acaagcattt ggagaaaaag gtgtcgataa acggatggga gaactttctg tagcaatcac
    31261 cggaaacttg acagtctttg atttgcctga tttggagttg ccttactctc caccgtattc
    31321 tactacccgt gacccgttga atatagctgg ttatgtcgca atcaatcaaa tgacgaatat
    31381 cgtagaaacg atcaaagcaa gtgatatacc cgaaaacgat ttgaaagaag cgttcttttt
    31441 agatatacgt gaacctaata aagcaccttc tggcagtatc tcggcaacaa aaaatattcc
    31501 aatgaatgag ttacgagatc gaatcaatga aatcccaaaa gataaaaaag tttacattac
    31561 tttcagaaga ggattgaata cttatacttc tgcccgaatc ttggcaggtt tgggtatcaa
    31621 agcgattttg attgaagaat aaaaaaacga ccgcggtggg tagccgcggt ctaggagtta
    31681 tttttacttg aggagtaaaa atgaaaaagt atatagggtt gttggttggt atgtatatag
    31741 aatagaagat aaatgtgaag aaattgtgca ttatttcttc acatttatta ggttatagtt
    31801 taagaaagtt taaacattgc gcaatttaat tattttagct gtttcttttc ataaaaaaac
    31861 atgttgtgac tctgagacaa atcatagtcc atagtgatgt ctctagagta actacgccta
    31921 atattacgag gcatcatatt aatctatcag cactagtacc taaactagca tccctttcga
    31981 atattttttc ttatataata aagtttgctt tcactcctct aatctcacca aatcgactgg
    32041 cttgcgttgt gtgatactag gaactgattg gtttagaacg acttttctat tgtaatcata
    32101 tttttcgcca tcctcgttgt cttctaatcc ttcaatgaat gatccctaat gtgtgtatta
    32161 aataatttaa tttttttgtt cctatttatt taac
//
LOCUS       DAIGSZ010000033        30718 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.033, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000033 DAIGSZ010000000
VERSION     DAIGSZ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.033"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            311..1090
                     /locus_tag="NOB31_001545"
     CDS             311..1090
                     /locus_tag="NOB31_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973756.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSYVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            1136..2080
                     /locus_tag="NOB31_001546"
     CDS             1136..2080
                     /locus_tag="NOB31_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCI0973757.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVAIVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            2096..2875
                     /locus_tag="NOB31_001547"
     CDS             2096..2875
                     /locus_tag="NOB31_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HCI0973758.1"
                     /translation="MEETINLEEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            2887..3585
                     /locus_tag="NOB31_001548"
     CDS             2887..3585
                     /locus_tag="NOB31_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HCI0973759.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3613..4377
                     /locus_tag="NOB31_001549"
     CDS             3613..4377
                     /locus_tag="NOB31_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HCI0973760.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            4422..5111
                     /locus_tag="NOB31_001550"
     CDS             4422..5111
                     /locus_tag="NOB31_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCI0973761.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            6338..7018
                     /locus_tag="NOB31_001551"
     CDS             6338..7018
                     /locus_tag="NOB31_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCI0973762.1"
                     /translation="MIGIEEKKGVQKDVTIDREENLRGHRFYWIGRRAQDIFFSALAL
                     IALSPVMLITALAIVIDDPGGSPIFVQDRVGRNGKLFKFYKFRSMCVDAEAKLEALLA
                     QNEMDGPVFKIKDDPRITRVGKFIRKTSIDELPQLWNILKGDMSIIGPRPALPREVEQ
                     YGDYERQRLFVQPGLSCYWQIAPHRNELSFEEWVELDVKYINERSFITDWKIIFLTLQ
                     AVLFGYGE"
     gene            7047..8360
                     /locus_tag="NOB31_001552"
     CDS             7047..8360
                     /locus_tag="NOB31_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCI0973763.1"
                     /translation="MNIILLSGGSGRRLWPLSNDIRSKQFIKLFKDENGEYESMIQRV
                     YRQITTVDPDAKVTIATSKSQASAIHNQLGDKASICVEPCRRDTFPAILLAAAYLHDE
                     LGVGDDESVAVCPVDPYVDNSYYEGVEALEKLVQQNTANLTLMGIAPTYPSEKYGYII
                     PESSNEVSTVKEFKEKPDKATAEKYLAQNAVWNAGVFAFKLGYLLEKAHAMVDFEDYR
                     DLYSKYETLTKISFDYAVVEKETSIQVMRYNGDWKDVGTWNMMAEVMADNIKGKAVMD
                     DTCVNTQIVNELNIPILAMGCKDMVIAASGDGILISDKERSGYMKPYVEKISTEVMFA
                     EKSWGTYTVMDVQEGSMTVKVSMQAGQKLSYHYHNSRDEVWTVVAGQGKAIVDGMKQI
                     LRAGDVVTIAAGCKHTIEAVTNLDIIEVQIGETISVADKYKSSLN"
     gene            9166..9933
                     /locus_tag="NOB31_001553"
     CDS             9166..9933
                     /locus_tag="NOB31_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HCI0973764.1"
                     /translation="MGIEGGYLMSRMRFMNTEIDNLTMGEVLVEVEKMIQDRRCGYVV
                     TPNVDHIVQLETGKELQDVYKNASLILTDGKPLIWISKFYKTPIKEKISGSDIFSLLC
                     KMAAEKGYTMYFLGAAEGVAAKAADNLMKRFPGLNVVGTYSPPYGFEKDEDEMFKIDS
                     QIKRANPDMLIVGLGCPKQEKFMFYNCDRLGVPVSFGLGASLDFEAGNVKRAPKWMSD
                     YGFEWLFRITQDPKRMAKRYLVDDLKIFKLALKYRKK"
     gene            9960..10961
                     /locus_tag="NOB31_001554"
     CDS             9960..10961
                     /locus_tag="NOB31_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HCI0973765.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFRENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSTELSYSRTERVTNIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALKGKYADKKKLVDKAIYLERVLCNEAGGWQDQIAAAYGGFNRI
                     NFNSDGYEVLPIIITPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAVLTDKNRDLDDFGRLLDLTWRLKKATGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQNAVRSAMSNLMYIPFEFENGGTQVIHYTPEMYIPK"
     gene            10984..12270
                     /locus_tag="NOB31_001555"
     CDS             10984..12270
                     /locus_tag="NOB31_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HCI0973766.1"
                     /translation="MKVVIMAGGKGTRISSVASDIPKPMIKIENKPVLEHEIECLRDQ
                     GFTDIILTVSHLGDIIMNYFGDGSGISPVTGQPFDVKIEYFLEKEPLGNAGALFRLKD
                     NLTEDFLLLNADAMFDVDFNRFVAYHREKGGLVTLFTHPNSHPYDSGLIIADKDGSVD
                     RWLVKEDSRPTYYRNRVNAGLHVISPAVLDVEINTPKIDLDRQLLKPLAGTGKMFCYD
                     SPEYVKDMGTPDRYYAVCEDFKAGRVKGKNLQNKQKAVFLDRDGTINQYVGFLRHIDE
                     FELIKGTEDAVKKINAAGYLAIVITNQPVIARGEVSFEELEEIHNKMETLLGYKGAYL
                     DAVYYCPHHPHKGYEEERPELKFDCECRKPKPGMLIQAATDFNIDLSQSWMIGDGEND
                     IKAGQAAGCKTALVGESEYGQDMTIATLSEFADKIC"
     gene            12304..12957
                     /locus_tag="NOB31_001556"
     CDS             12304..12957
                     /locus_tag="NOB31_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0973767.1"
                     /translation="MIDNRLQKHIDLLIKRYPTLEVIKQDIVDGYLIMEECYLNDGKL
                     LIAGNGGSAADSEHIAGELMKSFKTPRPVSREFADKLIAVDPVKGSELAKNLEYGLMA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRPGDVFLGISTSGNSKNVINATVVARA
                     LGMKVIGLTGAKGGELARVADVCVKAPETETYMIQEYHLPIYHCWCLMLEDKFFGNR"
     gene            12990..14195
                     /locus_tag="NOB31_001557"
     CDS             12990..14195
                     /locus_tag="NOB31_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0973768.1"
                     /translation="MNVLFITTQFPYPLDNGGKIGAYNGISVLSRDYDVTVLSFTEEP
                     QYVEEGVSFFREKFNSVKFENPVIHDVHIRNNPMKLVEALAIGYCLRQPYIVSKFYDS
                     KMLQLIDEKFSNNAYWDIIFIDYLNMQSYGQYIREKYKTQFGKYILKDHNIEYDLVLQ
                     EAESSRGLKKKLLQLEYKRTRKYEEAAVNRADYCFSVCDANTEVLKKINDNSYTMLPT
                     YEMLTGVKKNIEKNTILYLGNLSWKSNMQGLVWFLESIYPNIQQRIPDVKITIVGSGP
                     VGTDFSKYSGVDYRGYVKDISHIYDDQAVLIVPLLEGSGIRIKILEAFNNEIAVVSTL
                     VGCDTIGAKDGSELFIADNEKDFATAVVRLLEDMNLNEKVRKNAKLFLKEKYSLTARQ
                     DEFSAIINS"
     gene            14325..15650
                     /locus_tag="NOB31_001558"
     CDS             14325..15650
                     /locus_tag="NOB31_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973769.1"
                     /translation="MIVAAMSYHLTGNSNVASLIAVVGVVYAIVKACNNEYLAIWVMF
                     VLGSDIWGIVPYINIGSGVLHWSDFNVIVAIFLCLRFIKVKARSRYGIVYSVMLIFIL
                     IACVQSHSIYGQDVHTTLLTARELLVVISFWPIVKIVYSERITKNEFIDLVCKFTRWT
                     MCIYWFEWILVNMGFNITFLQTGARWGTRIYIDPIFIILYFFINLYAVIYKREGYNST
                     NKSIWNCIFSLLTFVIISQGRSGILYVVITSVIMLLISLKPSKIIRFGILGIALIACL
                     VSVTQIREVVISSFVESQSSDTGNIAYRIAEQDYFENKLEGHELFGVGIPNNHDARAV
                     EYSGKTIDFESKKYNPYYLEDLGAFEIRYRFGIIAYALYIVALAISIIDAGFRRDKSV
                     AAFAGMAFMVFMALNFNLLAYITARPFGFMISLILIEISAFNDEFIYIE"
     gene            15667..16797
                     /locus_tag="NOB31_001559"
     CDS             15667..16797
                     /locus_tag="NOB31_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973770.1"
                     /translation="MNLDRLKKIANMISPIIKVINAPLAYFSGKSDYMEKGILWPTVT
                     TYSNNSRKVIQYTTLPKNVDNMAQMQWAGESFEDICIVLQGPVLEDGDFTLNTVKMYN
                     KYYPKVKLVVSTWIGLSEETECKLREAGADVVLCKKPEKTGAYNINLQLTSAYEGVKM
                     AQKLGCSYALKTRTDQRLYANDVLKYFQTLLNIFPSSDCKVVNQRLIFTTYGKSFRYL
                     PFNLCDFLVYGETSELLKLYGIQRDNRASDFGKIIYTEEKEFNKKIFTLLEGKQGVSP
                     YDVFPDFDALYKKYMFAEYYIVYNYFLENIASNESYGDLMDAYYSYLKKYAVVADSEK
                     LLLYWPKYVQYNVKFENELDFYAKLDSKKWMDIYANYTPFSQ"
     gene            16823..17908
                     /locus_tag="NOB31_001560"
     CDS             16823..17908
                     /locus_tag="NOB31_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HCI0973771.1"
                     /translation="MKIGIVTIVNGASFGNRLQNYATQKVLENNGYTVETINNCFDKE
                     STLSIVIKNAIYTLFKFIPHFKKSKSIWKRMYTFYQWDKQYIDYSHRKIDASKKNSFV
                     SIKNDYDYFLVGSDQIWNPKYAANKGFELLSFVPNEKRVSLSTSLGVPSIPSDLEKLY
                     VTEWNKFKSISVRENQAAKIIEDLTGTTAAVHIDPTLMLERSEWEAFQKKPDNIDENY
                     ILSFFLTNPPKDTVDVLDKVAKDLKIGVLTLDASWEYFQDITPNHFVYLISHARMIYT
                     DSFHCTVFSLLFGKPVVVFDRFDSEKMNSRLSTLLNKVNKAHFWVGKKADEAMIRAIA
                     SEPEYDIDKLMVSERECVKAYLKEYLQ"
     gene            17931..18746
                     /locus_tag="NOB31_001561"
     CDS             17931..18746
                     /locus_tag="NOB31_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973772.1"
                     /translation="MEHLSDCFGKMKIVTTSCAREYFKDDLDKSEYSCFVDSRAAMFF
                     AMGQALAKRRNVVVMLADELTSCYTALTECAFQQVDLIVFAFQTVRHEIDLASLKNCG
                     CNLINCSAQDDIDRVVSNTKGLNQTTVIKINMNCESDKDHICEYIDLPDIPVFFHGSL
                     YSPASKKKYEQYGQVSKYLGYLVGGKDAILIISHNEFLNDISVWINYYSFGEIQPKII
                     IFDSPNDYQYKWLCDLECSVAHSTNRFLSEDLALLQNNGISIVLRGDNYDIVS"
     gene            18730..20448
                     /locus_tag="NOB31_001562"
     CDS             18730..20448
                     /locus_tag="NOB31_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylase"
                     /protein_id="HCI0973773.1"
                     /translation="MISSVKNVQILVSLLKQHNIKDIVISPGSRDFQLVHSVETDSFF
                     RTYTVVDERSAAFFANGLSMAIDKPVCVCCTSSTASSNYMAAAKDAFANGIQLVLLTA
                     DRDYRRLYQMEDQMIDQVDMYGAYVRSNVDIPIVKDSDDEWYATRKINEAILELNHGV
                     KGPVQINYQLMDLSAPFVETMPEYRKITRYQEDDLLSSVEIFKQKLLSKKRIMVLCGQ
                     QEENNLSALLEEFFIKYNTIIIKDNYSNIHGEHFIKTVLVTERMSVNAFIDYCPDLVI
                     TIGKHVWSFVKYTLRDKKLKFEHWRISEDGKIVDPFNKLTSVFQCSAEFFMETVTAGV
                     NSNNNLEYYNLWKTRLSKVCYPELVYSNFYAISELVKKIPDSALVHSSILNAARLYDF
                     VSDDKALLSFANLGADGIDGCLPTFLGQAEADKTRPAYLISGDLSFFYAMNSLCGDIP
                     DNAHIFLINNHSGSEFHTNFGKFYNGSLSVDKHIAAGHISNAKDWALENNIKYITADS
                     KESLKSGLDVFINTFDSPVLFEVFTDPDTDTSVLESFYSINKVITPKMYFRKALDIIK
                     KHLHIK"
     gene            20474..21310
                     /locus_tag="NOB31_001563"
     CDS             20474..21310
                     /locus_tag="NOB31_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0973774.1"
                     /translation="MAIKSYIKRLLLYIRHGDPKINLDVSYLSEGAMLAGKTVIITGG
                     AKGLGFAIAKSFIAQGASVIITGRDMDSLNNAKCQLGDMCSIRAFDITDAKMYRTFFE
                     DAYETFGRIDILLNNAGISLHEDGFMSVTEKTWDKQMDTNLKGVYFFTQEFIKFVKEK
                     NQMQANIIMMSSERGLCGDSIPYGLSKAAINSLVVGLSKKYISEGIRVNGIAPGVTAT
                     AMTGISEKGNLYNPATIGYRYFLPEEVAQVALFLASSLSNCISGEIIACDKGQYLSRN
                     WG"
     gene            21315..22748
                     /locus_tag="NOB31_001564"
     CDS             21315..22748
                     /locus_tag="NOB31_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HCI0973775.1"
                     /translation="MGILLKKYNSLSEPAKASIWFTLCNVLQKGILFLTTPIFTRMLS
                     TAEYGKYTIFISWYSIIAIFTTLNLSAGVYNKGLIKYENKYALTSSFLGLSSFISLCA
                     LMLYLPFRTVINGLLDLSTEFVILILIESIFEPAFLLWSVKERFDYKYQKLVLITVLM
                     AVLNPGLGIILILSFGEYAIWRVRAYVVVNVVVGMFIGIGILAKGKKLFDKEYWTYAL
                     RFNLPLIPHYLSMTLLNQVDRLMINSMVGASEAAIYSIAYTISSMMNIITTAINGSFI
                     PFTYKAIKDGVYEKIKSVANQLLVLIFVLCSFTMLFGPELIWVVGGEKYMDAVWIIPP
                     VAASVFFMFLYPLFGNIEFYYEKTNYVMFASCVGSIAKIISNYVSIPRFGYISAGYTT
                     LICYMLFSFAHYMFYKKILRENGIKEDMYNIKNIIFLSVLMIVLTIGMTILYFSTILR
                     YSIIIGLVIVAFLKRTQIMKILKNIKN"
     gene            22786..24426
                     /locus_tag="NOB31_001565"
     CDS             22786..24426
                     /locus_tag="NOB31_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HCI0973776.1"
                     /translation="MRLLIPSAKIVPEELHHLGKLPAIIYPINQKIVFDYLYDQYKDV
                     CSAIDIACYEKMDKVARRLDKYIKSKTVNIIQLKELGDLGRTIYDSLIGCDEPVIINF
                     ADTIINDNIYSLECDSFFYAEDYYSNTWTFFEEKDGDIISVLDKNELKEDDGKKHKLF
                     SGVFQIMDAQYFRECLRKALMSNVVNVNSFYQALQEYSKRYEFLSIKTNNWFDIGHAD
                     KYYNSKLEVKAREFNHISIDKDRSILRKISEDVEKFIGEIKWYLKLPAQVEYVRPRIF
                     EYSTSYINPYVSMEYYSYHTVHELFLYSDLTKKQWIDIFNRIRFVCSDFKRYSVSGDN
                     IQKSLKDMYLDKTFQRFNKLRKDPRFTEFFSSDIQINGVRYKSLDQIEALLSVSVPRE
                     LFDITQFNIIHGDLCFANIMVDNTFSFIKVIDPRGKFGDFDIYGDYRYELAKLFHSVD
                     GKYDFIIKDLFTIKYDPKKAIIDYIVQDRKRDYDLYEVFYSVFKDEIGSDLKKIELIE
                     ALLFLSMIPLHGESLNHQMAMLATGLEILGRVVPDIYC"
     gene            24514..24912
                     /locus_tag="NOB31_001566"
     CDS             24514..24912
                     /locus_tag="NOB31_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HCI0973777.1"
                     /translation="MFKDYAFVFDIDGTLCPIKKKDEKYEDLVPYANMVEKLRYYKEN
                     GAKITLFTSRNMNSYHGNLGVINANTAKILLAWLDKWEIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLSCTLDQLDEICKKSKLKSE"
     gene            24937..25653
                     /locus_tag="NOB31_001567"
     CDS             24937..25653
                     /locus_tag="NOB31_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0973778.1"
                     /translation="MTVIITMAGLGSRFRKVGYTVPKFMIEAKGKTLFDWSLDSLLDY
                     NSHVEKYVFVVRKEDDATVFIKEHCSLYGIENVEVVEIDYMTDGQATTCMLAIPYCAP
                     DNAIMVYNIDTYVEPGEMKYVDISGEGHIPCFHADGDHWSFAKLNEYGDVVEVREKVR
                     ISNNCTLGAYYFSSAKLYASLYEEYYADERHLEKNEKYIAPLYNYMIEKGMKVTISIV
                     DKSKVHVLGTPEELDVFLNE"
     gene            26885..27464
                     /locus_tag="NOB31_001568"
                     /pseudo
     CDS             26885..27464
                     /locus_tag="NOB31_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
     gene            27524..29176
                     /locus_tag="NOB31_001569"
     CDS             27524..29176
                     /locus_tag="NOB31_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HCI0973779.1"
                     /translation="MDHNANYYHWLTNANAEIVEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLSDYLNKTYETPSVVVGYDSRIKSDVFAKVAADIF
                     AANGIQVHLWPELLPVPTVSFAIRYLKASAGVMITASHNPSKYNGYKVYGAGGCQITT
                     EAAAEILAEIEKLDIFADVKMGGDASRIASIQPEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEINEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKNAEGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PTDPVMVKTIVTMDLGERIASNYGVRTVDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLFDKLNEIYAKYGYCLNTLHSF
                     EFEGAAGFTKMQKIMVEFHKGLDMIGGKKVIETLDYSTGLNGLPKSDVLKYLLEGNCS
                     VVVRPSGTEPKLKTYISVSAESKEAAEVMEAVMAAELAEMFK"
     gene            29520..29885
                     /locus_tag="NOB31_001570"
     CDS             29520..29885
                     /locus_tag="NOB31_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HCI0973780.1"
                     /translation="MYYFQQSYLPAILNKAISIGDTGVHIFFFCSGFGLYLSYLKKPI
                     TLGEFLQKRFIKIYIPYIIVITVSVLLPYMTQDLNAAKVYLSHVLLFKIFLPVYEESL
                     GPFGLFRQLFSSISYSYQL"
     gene            29973..30416
                     /locus_tag="NOB31_001571"
     CDS             29973..30416
                     /locus_tag="NOB31_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973781.1"
                     /translation="MEAYEFLGAALRNIFGNLLSACLVAEYLVKRKIVRFNNIFVIMA
                     SIVGIGFAGISKIIGGLMESINDIFAFFGYGAIAILMYQVIPFRKIMPRISRYSYDIY
                     LLHILVFSTIHQIIPNLVLAAFVSIPITLVLSYYYSIMLYRLKLK"
     gene            complement(30571..>30718)
                     /locus_tag="NOB31_001572"
     CDS             complement(30571..>30718)
                     /locus_tag="NOB31_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI0973782.1"
                     /translation="EKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRY
                     SLGY"
BASE COUNT        10004 a         4479 c         6589 g         9646 t
ORIGIN      
        1 tattattaat tcaatgttaa tttttttgtt attttatttt ttgtgtaact tttaaaaaca
       61 cctatgaaaa ttaaggaaat aaaaatgaaa tcgattaatt gttatcttat tactgtttta
      121 tttactttta aatcataaat tgccctagtc aagaaaacag tttgtggtat gattatatag
      181 ggaaaacttg tttacaaata tttctgtgaa tatattagtt taattatgtt ttttaaaata
      241 aaaagctgtc atttttatgt aagtgaatta tatcttaatt tatctatcat caatacttag
      301 gagtgaatct atggaaaagc cattcgtcaa gtcattgact gctgtggcgg taggtgcagg
      361 tgctattgcg atctgtttgt ttggttacca tatcaataat cagcggcaac atcagcaacg
      421 gatcaattat gcagaatctg ccatcaccaa tcaaaaagac accttgactt ctttatcaaa
      481 agaagtagac aagctgtata gtacaaaaga aaaaattttt ctaaaccctg aaataacaga
      541 agaaacaatc acaagtttgt caaataagct atcctatgtc aaactttcag cagatgatta
      601 cgacatcaaa gaatcagaat tgcctaaaga agctgttgca atccaagatg agaagaaagc
      661 aatcgtgaca cagttagata gtgcagaatc aaaactgaag atccagacag ctgtcaacga
      721 tttgtttact aaaaatgtat caaactggca gcaagctgta gacgatgtca tcatcaaaga
      781 aaaggtgaca agtgcagatg tcgctcgtgt acgtgaaaat atgagctttt ttaaagatag
      841 tccttggaaa acggttgtta tgcaatattt aggattcgct gatactcaga tcgcgcaagt
      901 cacgcaacta gatcagttat tcgatacgat gttgaaggat ggtcaagtga ctgccaccgc
      961 tacttacgat caatatttga cggcgctcag tcaaatagag cagatccgga atgaaaaaat
     1021 aagcgcagca tacgcaacaa aagcacaaac tgttgctcag caaatgggct atagcaatat
     1081 aagttattga cagttaaaac gttgattcaa gcaaggttag caaacggagg aaactatggc
     1141 aagacgaaga agaaaatcaa gagggaaaaa aatatttctg attattttag cagttcttat
     1201 cgtattagta ttagcaattg taggagtagg agcaaaatta tatctggatc tctcacattc
     1261 tattgagaaa acttacgaat cagtggaacg aacccaagga gaacgaacga aaccagttga
     1321 tctggacaaa caagaatctt tctctgttct attgatgggg attgatactg gagatttagg
     1381 tcgggtcgat caaggaagat cagatacgat gatggttgcc atagtcagtc ctgaagacaa
     1441 acagacaacg atcgtcagca ttcctcgtga tacgtatgtc gacatcgtag gtcgtgacac
     1501 aaaagacaag atcaaccacg cttacgcatt cggcggagct gccatggcga tggataccgt
     1561 acaaaaatat gtagacatcc caatcgatca ctatgtctct atcaatatga aagggctaaa
     1621 ggaacttgtt gatgcagttg gtggtatcga agtcaataat gacctcactt tctcacaaga
     1681 tggctatgac tttacaatcg gtaaaatcac attgaacggg gatcaggcat tatcttattc
     1741 tcgtatgcgt tatgaagatc caaatggtga ctatggtaga caagagcgtc aaagaaagat
     1801 cgtagaaggt gtagcaaaaa aagtattgag tttaaacggt gtcagcaact atcaatccgt
     1861 tttgaatgct ctagagtcga atatgaaaac agacatgagc tttgatgaaa tgaaaaaaat
     1921 cgctttagat tatcgggagg catttggtac gatcaagcaa gatcagctgc aaggagaagg
     1981 ctttatgcaa gataatatct cctatcaaaa agtcagtgat caagaacttg atcgtgtaaa
     2041 aaaagaatta aaagatcaaa tgaatctaga gaataaatag gaaagtggag aaaaaatgga
     2101 agagacaatc aacttggaag aaatttttga aacattacgc aaacacttgg taacaatcat
     2161 catctcaatg tttgctggct tggccatctc aggaatcgta acatttttca tcttgacacc
     2221 aaaatacagt tcacaagcac aattgatcgt gacactgcca caatcagaca cagcaaatgt
     2281 caatgatgtc aatacgaacc tgcaaatgat caatacgtat aaagatatga tcgtcagtga
     2341 tttagtacta aatgaagtca aagatcgttt agaaacagaa gacaatgtga aaatgactgc
     2401 tggacaaatc aaagatgcga tctccgtcaa tcagtcacaa aattcacaaa tgttctcgat
     2461 ccaggcaata agcacgaatg cagtgactgc tcaacagatc gctaacacaa cttcacaagt
     2521 tttccaagag aacgcaaaag acgtgatgaa tgtcgataaa atctcgatta tttcaggtgc
     2581 agttgccaat acgacacctg tttcgccaaa taataaattg aatctagtga ttggcttagt
     2641 attaggaatg atggtaggcg taggtctggc attcttattc gaattacttg atcggacagt
     2701 gaaagatgaa aaatatgtga cggatgcatt aggattccca atcttaggaa cagttccaga
     2761 aatgtcagcg aaagaattga acgctggtat ccgtaaaaaa ggaacagctc ctgcacgacc
     2821 aaaagctaca aacgataaaa cagccccatc acgcagaagc cgctcaagag tctaggagga
     2881 agaaaaatgg cacgaacaca gaaacaaaaa gcagcacaaa ctcatgcagt cagtttgatc
     2941 acattaacaa acccatcttc accaatcgcc gaacaatatc gtacgatccg gacgaatatc
     3001 cagtttgcct ccgcagctgg tcagcaaatc aaaacgattg tcgtgacttc atcaggtcct
     3061 ggagaaggaa aatccaccac tgcagcaaac attgcagtcg tttttgctaa atccggtcaa
     3121 cgagttctac tagtcgatgc agatttacgt aaacccgtcg tctataagac attccagctg
     3181 aacaatgcca ggggattaag tacagcactt agttcatcag gaagtgtagc agatgtaatc
     3241 caacgaacgc cagtcgagaa cttgtcgatt ttgcctagtg gacctaagcc acccaaccca
     3301 tcagaattgt taagttcgcc aagaatggat cagatcctag acgaagcaag acagttattt
     3361 gacgtggtga tattcgatat gccaccagta gtagccgtaa cagatgcaca gatcatgtct
     3421 tcaaaaacgg atggcacttt attggtcgta cgtgaaaata catcacgtaa agaatcattg
     3481 aataaagcaa aagaactgct agagatggta caagcacgag ttttaggtgt tgtatacaac
     3541 ggagcagaac atagcaaaga tgctggttat tactacggaa attaaggaat aagaagagag
     3601 gagacaagag aaatgatcga tctacattgc catatcctac caggaatcga tgacggggca
     3661 gaaaacttag aagcaagtat tgcaatggct gaaaaagcga ttcagcaagg catcacgcat
     3721 attttatgca caccacacca caataatgga aaatacagca atgaaaaatc acaagtcatt
     3781 tctctagtcg cttcgttaca agccgaatta gagaaaagac agttgccttt gacgttattg
     3841 gaaggacaag aagtacgtat taccggaacg ctcatcgaag acatccaccg agatgaaatt
     3901 ttatttacag atttagatga tacatatctt ctgatcgaat ttccgacact ggaagtgccg
     3961 ttatatgcag aatggctttt ttttgagttg ttagaactag gaaagacacc agtgatcgtc
     4021 catccagaac gcaacgcgca ttttcgagaa gacccaaatc atttgcttcc gttcctagat
     4081 atgggatgtt tggcccaaat tactgcgcca agttatgttg gtgtatttgg caaagacatt
     4141 cagaaaacag ccaaaacaat ggtcaaacat aatctcgtgc agatggctgc ttctgatgcc
     4201 catggggtct ctaagcgtac cttttactta aaagagtgct atgagcagat tgctaaggac
     4261 tttggtaagg aaaaagtagt acagatgaaa caagtcgcaa aggatctgat caacggggat
     4321 gaaatcagtt atccagtcta tgaagaggta aaaaagaaga agtttggttt attttagttc
     4381 tttattcgta gataaaaagg aaatgaggag agagggaaag tatggaaagt gaagatttat
     4441 tatctcgtat tagtgaagta catcctaatc aagtttggtt ggataaagaa aaagttgaaa
     4501 aacgatatat ctatttattt tttaaaagaa tgattgatat tgtaggaagc attattggtt
     4561 tgattttagc ttctcctttg atgttctatg tagcttatcg aatcagaaaa gaagagccag
     4621 gaagtccgat atttttttgc catacacgtg ttggtaaaaa tggaaaaaca ttcaaaatgt
     4681 ataaattccg ttcgatgtgt ttagatgctg aagaaaaatt ggaagaatta cttgatcaaa
     4741 atgaaataga aggtgcaatg ttcaagatga aagaagatcc ccgtgtcact aaaataggta
     4801 aaattatccg tgccaaaagc attgatgaat tgccacagct atggaatgtt ttaaaaggcg
     4861 atatgagtct aattggtcca cggccacctt tggagaggga agtagctgag tacacgagat
     4921 atgatcttca acgcttgtat gtaaaacctg gttgttcagg tttgtggcaa gttagtgata
     4981 gaaataatgt tagtttccat aaaatggttg agttggattt agagtatatt agtcatcgaa
     5041 gtttaatgta cgacttgagg ttgattttaa aaacgtttta tgttattgtc aagcccaatg
     5101 gagcatatta gttagggata gaatgatgga ttgttaataa aaaagattac acatgttcat
     5161 attatcgttt caaaagtaat aactgtaatt atggagggtt tgaatcactt gtagaaaatc
     5221 taaaaaaaga aaggtgaatg gggcaattca gtatcattat tcttatataa aagaaaatat
     5281 tcgaaatttt gggatgatac cactcttaaa tataatgatc taaatgcttt aatattggta
     5341 tatccgatat aggaactgac gagctattta gtatgataca aaagtatatt gatagccatt
     5401 aataaatttt ccaaaaaata atgacagcac accaattttt ataatttagc ttgttgaatc
     5461 ggtatgttca tgggacggtt caaaaaaaga atcgaaaaaa taaacggtaa aattttagtg
     5521 aatcctatgt aataaaattt ggatagatgg aaaaacagca cataaggagg ctgagtttgt
     5581 tgtcatttct gctcctacaa actatggtag tgaatgtgtt attgaattag tgatgtctgt
     5641 tacttcagag acattgggga taattaactt cactatacct gtagggtata caaaaaatgg
     5701 aagaaaaaat attatcaata gattttattt agttcagaat ttttacgtgg aagtaaatta
     5761 ttgatgataa tctttatcca attagaatta ttatcgtagg atgtgatgat gatagccgtg
     5821 aagttgttca agtatttacc aatgtctaca acgcagaaaa ttagtttggg tttttcggat
     5881 tggaaaattt caatgtataa aatcataaat ttgctgtaaa tagacagttt ggggtagtaa
     5941 tagcccaata aattgttcga taaactcatc tttggggtga gaatagctca atcattgaat
     6001 ttcaaacctg cctttggggt gggattagag gtcaatatgt acctacataa tactttttgg
     6061 aaaatgatgg tgttgagaat gtaagtacat ttcaatgtga aattctaata tagccccaaa
     6121 cgaggtcaat aaaaatgacc taaactcgta tttctcccct aaacgaggag gagatagata
     6181 tgaaaattga atgtgccggc gttggagttg gctgctttta gtaggaatga acatggttcg
     6241 atgagaactg tttcagatag agtggtcgat gatcacaggc ctttaagtcg tttacagatg
     6301 atgagacttg taaaaataga gggacgaatg gaaaaagatg attggtatag aagaaaagaa
     6361 aggtgttcag aaagacgtaa caattgatag ggaagagaat cttaggggac atagattcta
     6421 ttggattgga cgcagagcac aagatatctt cttctcggct ctagctttga ttgcattgag
     6481 ccctgtgatg ctaattacag cgctcgccat tgtgattgac gatcccggtg gcagcccgat
     6541 ttttgtgcag gatagagttg gaagaaatgg aaagctgttc aagttttata aattccgatc
     6601 tatgtgtgta gatgctgaag caaaattaga agccttgttg gcacaaaacg agatggatgg
     6661 tccggtcttc aagattaaag atgacccaag aatcacgaga gttggtaaat ttattcgaaa
     6721 gacaagtatc gatgagttac ctcagctctg gaacattctt aaaggtgata tgagtattat
     6781 tggacccaga cctgctttac cgagagaggt ggaacaatac ggtgactacg aaaggcagcg
     6841 gttgttcgta cagcctggtc ttagttgcta ttggcagatt gctccacatc gtaatgaact
     6901 gtcctttgaa gaatgggtgg aacttgatgt gaagtacatc aatgaaagaa gctttatcac
     6961 ggactggaag attatcttct tgactttaca ggctgtatta tttggatatg gtgaatgatt
     7021 atatatagta ttaggagttg aaatatgtga atattatttt attatcgggt ggtagcggta
     7081 ggcggttatg gccgctgtcc aacgatattc gtagcaaaca attcatcaaa ctgtttaagg
     7141 atgaaaatgg cgaatatgaa tctatgattc aaagagttta tcgccagatt acaactgttg
     7201 acccagatgc aaaggtcact attgcaacaa gtaagtctca ggctagtgca atccataatc
     7261 agttgggaga taaggcttcg atttgtgtag aaccttgtcg tagagatact ttccctgcaa
     7321 ttttgttagc tgcagcatat cttcacgatg aacttggcgt aggtgatgat gaaagtgttg
     7381 cggtttgtcc tgttgatcct tatgtagata attcctatta cgaaggcgtt gaagcccttg
     7441 agaagttggt gcagcagaat acggctaatt tgactttgat gggtattgca cctacatatc
     7501 ctagtgaaaa gtacggttat atcatccctg aaagttctaa cgaagtaagt actgttaagg
     7561 agtttaagga aaaacctgac aaagcaacgg cagagaaata tttagctcag aatgctgttt
     7621 ggaatgccgg tgtatttgcg ttcaaacttg gttacctgtt ggaaaaagct cacgcaatgg
     7681 tggattttga agattatcgt gatttgtatt ccaagtatga gactttaacc aagatcagct
     7741 ttgactatgc tgtggtcgaa aaagaaacga gcattcaagt gatgcgttat aacggggatt
     7801 ggaaagatgt cggaacttgg aacatgatgg ctgaagttat ggctgataat attaagggga
     7861 aagctgtaat ggatgatacc tgtgttaata ctcagattgt gaatgagttg aatattccta
     7921 ttcttgctat gggctgcaaa gatatggtaa ttgcagcaag tggcgatgga attctgattt
     7981 ctgataaaga gcgcagtggc tatatgaagc cgtatgttga gaaaatcagt acggaagtaa
     8041 tgtttgcaga aaaatcctgg ggtacatata ccgttatgga cgttcaggaa ggctccatga
     8101 ctgttaaagt ttctatgcag gccggacaga agttgagcta ccactaccac aattctcgcg
     8161 atgaagtttg gactgttgta gcaggacagg gtaaagcgat tgtagatggt atgaagcaga
     8221 ttcttcgtgc gggtgatgtg gtgactattg ccgcaggatg taaacataca atcgaagccg
     8281 tgacaaatct ggatattatc gaagttcaga ttggtgaaac tattagcgtc gctgacaagt
     8341 ataagagttc tttgaactaa aagttcgcga ggtagttatt atggagatac taaaatttca
     8401 acccgtgggt aaagattatc tttggggtgg agaacggttt aagacggaat ttggaaaaaa
     8461 ttgacttaac accattaagc ttatacgtgg gaatgcttag ttcatctaga cgataactac
     8521 gtacggaaat atcaaatatg aaggacagaa tggtaaaacc gagttgtggt atgtattgga
     8581 agctacaccg gggggtgatt tatgcttttg agtacgatgt aacagaagaa atgttacgaa
     8641 atgctgtgat ggacagatca cttgggaaac atttatataa agaagaagta cacaagggag
     8701 atctttttta tgtcagttca tggtattggc gctggagtat tagtggctga aatacaggaa
     8761 agctcaaatg ttacctatcg agtttacgat tatgatcgag tagataagaa tgataataag
     8821 tgagaattgt actttgaaaa agcgattcag gtaatgaata tggaagccac tttgaaattg
     8881 gagaaaagaa ataagctcat tcatttttat cctggtggct ctcgtgaaat actgtgtaga
     8941 tgtaaatact gtgagcccga aagaatccaa gtaaagacgg ggttttcgtt ctcggtaaaa
     9001 gaggaatctt ttcaagttct tttatgtata tcgggggacg gacaagttga gtcggcaaat
     9061 ggtgttatga aactcattag atttgtaaaa aagatattgt atgtttttgc caacgaatat
     9121 tggaagatgt taagtgttga gcgatgcgga cttactgaaa attagatggg gatagaggga
     9181 ggatatctaa tgtcacgaat gagatttatg aacacagaaa ttgacaatct tacaatgggt
     9241 gaagtattgg tagaggttga aaaaatgatt caagatagga gatgcggata tgttgtaact
     9301 ccgaatgtgg atcacattgt tcagttggaa acaggaaaag agttgcaaga tgtttataaa
     9361 aacgcatctt taattttgac ggatggtaaa ccattgattt ggatttcaaa gttttataag
     9421 acaccaataa aagaaaaaat atcgggatcc gatatatttt ctttactgtg caagatggct
     9481 gcagaaaagg gatacacaat gtatttttta ggtgcggcag agggcgttgc ggctaaagcg
     9541 gcagataacc tgatgaaaag atttccggga ttaaatgttg taggaacata ctctcctcct
     9601 tatgggttcg aaaaagacga agatgaaatg tttaaaattg attcccaaat taaacgagca
     9661 aatccagata tgcttattgt gggtttgggt tgccctaaac aggaaaaatt tatgttttat
     9721 aactgtgata gattgggagt acctgtgtct tttggtctag gagctagttt ggactttgag
     9781 gcagggaatg ttaaaagagc accaaaatgg atgtcagatt atggatttga gtggctgttt
     9841 agaattactc aggaccctaa aagaatggca aaacgatatt tggttgatga tttaaaaatc
     9901 tttaaattag cactaaaata tcggaaaaaa taaactatat tcaatgagga caatgaagta
     9961 tgattattac aaaaacacct tttcgcatgt ctttttttgg cggcggaacg gatatggaag
    10021 attattttcg agaaaatggc ggtgcagtgc tttccactac ttttgataag tactgttatg
    10081 tgaatgtgcg tcatttgcct agattttttg attacagcac agagttatca tattctcgta
    10141 ctgagagagt aacaaatatt gaagatatcg agcatcctgc aattcgtaat gcgatgaaaa
    10201 tgctagatat gcatgaaatt cgccttacat atgaagcaga tcttcctgca cgttctggtc
    10261 tgggtacatc tagttctttt gccgtaggta tgttgaatgc tttctatgct ttgaagggca
    10321 agtacgctga caagaagaaa ctcgttgata aagcaattta tcttgaaaga gtcctttgta
    10381 atgaagcagg cggatggcaa gatcagattg cagcagctta tggtggcttt aaccgaatca
    10441 atttcaactc agatggctat gaagtattgc ctattattat tacgcctgag cgtaaaaagc
    10501 agcttaacaa caacttgatg atgttcttta ctggattcac cagattttcc tctgatgttc
    10561 agaaggcaaa taatgtcagc ggcacagagg acaaaagagt aagactgaaa aaaatgtatg
    10621 agcttgtgga tgaagcagaa gcggttctga ctgataagaa cagagatcta gatgatttcg
    10681 gcagactgct tgatctcact tggagattga aaaaggctac cggtggtgcg attagcactg
    10741 gaagtatcga tgaactttat gaaaagggca tggctgctgg tgcattgggc ggtaaacttc
    10801 tcggagcagg tggcggcggt ttcttggttt tttatgttca gcctgaaaaa caaaatgctg
    10861 tgcgttcggc aatgagtaat ttgatgtata ttccgtttga atttgaaaac ggtggaacac
    10921 aggttattca ttacacaccg gaaatgtata ttccaaaata aagaaatcag cgaggataag
    10981 aatatgaaag ttgttattat ggcaggcggt aagggaactc gcatctcatc ggttgcaagc
    11041 gatattccaa agcccatgat taaaattgaa aacaaaccgg tattggagca cgaaatcgaa
    11101 tgtctgagag accagggatt cacagatatt attcttaccg ttagccatct tggcgatatc
    11161 attatgaact attttggcga tggttctgga atttcaccag ttactggtca gccctttgac
    11221 gttaaaattg aatacttttt ggagaaagag ccattaggaa atgccggtgc attgtttcgt
    11281 ttaaaggata atttgaccga agacttcctc ctgctgaatg cagatgcgat gtttgacgtt
    11341 gatttcaacc gatttgtagc atatcaccgt gaaaagggtg gcttggtgac attgtttact
    11401 caccctaaca gtcatccata tgacagcggt ctaatcattg cagataagga tggctctgta
    11461 gacagatggc ttgtaaagga agattcccgt ccaacttatt accgtaacag agtaaatgcg
    11521 ggactccatg tgattagtcc tgctgttctt gatgtcgaga taaacacacc taagattgac
    11581 ttggaccgtc agttattaaa gccgttggca ggaaccggaa aaatgttctg ctatgatagt
    11641 ccagaatacg taaaagacat gggtacccct gatcgttatt atgctgtctg tgaagatttt
    11701 aaggctggaa gagtgaaggg caaaaatctt cagaataagc agaaagctgt tttccttgat
    11761 cgtgatggaa cgattaatca atatgttggc tttctgcgtc atattgatga gttcgaacta
    11821 atcaagggta ctgaagatgc agtgaaaaag atcaatgccg ctggatatct ggctattgta
    11881 ataacgaatc agccagtaat tgcaagaggt gaagtttctt ttgaagaatt ggaagagatc
    11941 cataacaaaa tggagacact tcttggatat aagggcgctt atttggatgc agtttattat
    12001 tgcccgcatc atccacataa gggatatgag gaagagcgcc cagagctaaa attcgattgt
    12061 gaatgcagaa agccaaagcc cggaatgtta attcaggcag ctacggactt caacatagat
    12121 ttgagtcagt cttggatgat tggcgatggc gagaatgata ttaaagcggg ccaagccgcc
    12181 ggctgtaaga ctgcattggt tggcgagagt gagtatggac aggatatgac catagcaacc
    12241 ctgagtgaat ttgcagataa gatctgctaa gggatgtttt atcacgaaag gagagtataa
    12301 acaatgatag acaatagatt acagaaacac attgatttgc tgattaaacg ctatcccact
    12361 cttgaagtaa tcaagcagga tattgttgac ggatacctga ttatggagga atgctattta
    12421 aatgatggca agctgctgat agcaggaaat ggcggatctg ctgctgattc cgagcatatt
    12481 gcgggtgagc tgatgaaaag ctttaagacg cctcgccctg ttagtaggga atttgcagat
    12541 aaattgattg cggttgatcc tgtaaagggt tctgaattag ctaagaatct tgaatatggt
    12601 ttgatggcga ttcctctcgt tgctcatgaa gcgctttcca ctgcgtatat taatgatgtt
    12661 gatggcctag gtgttttcgc acagcagttg tttggatttg gaagacctgg cgatgtattc
    12721 cttggtattt cgacatccgg caatagcaaa aatgtgataa atgcaactgt tgttgctaga
    12781 gctcttggta tgaaagtaat tggcttaact ggagccaaag gtggagaact tgcaagggta
    12841 gcagatgttt gtgttaaagc tcctgaaaca gaaacatata tgattcagga gtaccatttg
    12901 ccaatttacc actgttggtg tctaatgttg gaagataaat tttttgggaa tagataaaat
    12961 atctaagccc atattgaaag gataaaatta tgaatgtact atttataaca actcaatttc
    13021 catatcctct agataatggc ggaaaaattg gtgcgtacaa cggtatcagt gttttatcta
    13081 gagactacga tgtgacggta ttgtctttca ccgaagaacc gcagtatgtt gaagaaggtg
    13141 tcagtttttt tcgagagaaa tttaatagtg taaaatttga aaatcctgtg atacatgatg
    13201 tacacataag aaataatcca atgaaattgg tagaagcttt agcaataggg tattgtctac
    13261 gccaacctta tatagtttca aagttttatg attcaaaaat gctgcagtta atagatgaaa
    13321 aattttctaa caatgcatat tgggatatca tttttattga ctatctgaat atgcaaagtt
    13381 atggtcaata catacgggag aagtataaaa cacaatttgg taagtatatc ttaaaagacc
    13441 acaacataga atatgattta gtcctacagg aagctgaatc aagtcgaggt ttaaaaaaga
    13501 agttgcttca gttagagtat aagcgtactc gaaagtatga agaggccgca gtaaataggg
    13561 ccgattattg ctttagtgtg tgtgatgcaa atacggaagt actgaaaaag attaatgaca
    13621 acagttatac gatgcttcca acttatgaaa tgcttacagg ggtgaaaaaa aatatagaga
    13681 agaacacgat cctatatttg ggtaaccttt cttggaaatc caatatgcaa ggattagttt
    13741 ggtttttaga gtcaatttat ccaaatattc aacaaagaat tccggatgta aaaatcacaa
    13801 ttgtcggtag cgggccagtt ggaacagatt ttagtaaata ttcaggcgtg gattatcgtg
    13861 ggtatgtaaa agatatttca cacatttatg acgatcaagc ggtgctaatt gtacctttgt
    13921 tagaaggtag tggtataaga ataaaaatat tagaagcgtt caataatgaa attgcagttg
    13981 tatctacatt agttgggtgt gatacgattg gcgcaaaaga tggaagtgag ttatttatag
    14041 cagataacga aaaagatttt gcaacggctg tagttagact gcttgaagac atgaatttga
    14101 atgaaaaagt aagaaagaat gcaaaattat tcttaaaaga aaaatactcc ttaacggcta
    14161 gacaagatga gtttagtgcg ataattaaca gctaatatat atataagctt atctgatgat
    14221 gatttatagg aggaaatata tggagatggc tgagagaaag gaaaagaaac ttggaaataa
    14281 gaatatcata ttattttaga aaactcctgt tattttatgt ttgtgtgatt gttgcggcta
    14341 tgagttacca ccttacaggc aattccaatg tagcgtcatt aattgctgta gtaggagtag
    14401 tttatgctat tgtaaaggcg tgtaataacg agtatctggc tatatgggtt atgtttgtat
    14461 taggttctga tatatggggg atagtgccat atattaacat tggtagtggt gtgttgcatt
    14521 ggtcagattt taatgttata gtagcgatat ttctctgctt gagattcatc aaagttaaag
    14581 ctaggagtag atacgggatt gtctatagtg taatgcttat atttattttg attgcatgtg
    14641 tgcaatcgca ttcaatctat ggacaagatg tacatacaac gctcttaaca gctagagaat
    14701 tgctagttgt aatatccttt tggccgatag taaaaatagt atattcagaa agaataacta
    14761 aaaatgaatt cattgattta gtgtgtaaat tcacaagatg gacaatgtgt atatattggt
    14821 ttgaatggat tcttgttaat atgggattca atataacctt tttacagaca ggtgcacgct
    14881 ggggtactag aatctatata gatccgatat ttatcatttt atatttcttt ataaatctat
    14941 atgcggttat atataaaaga gagggctata atagtacaaa taaaagtata tggaattgca
    15001 tttttagttt actgacattt gttataatct cgcaaggcag aagtggtata ttatatgtag
    15061 taataacctc ggttattatg cttttaattt cgcttaaacc atccaagatt attagatttg
    15121 gtatattagg aattgcctta attgcatgtc tagtgtctgt gacccaaatt agagaggtcg
    15181 ttatatcttc gtttgtagag tctcagagca gtgacacagg taatatcgca tatagaattg
    15241 ctgaacaaga ttattttgaa aataaattag aaggtcatga actatttgga gttggtatac
    15301 caaacaatca tgatgccaga gctgtagaat attcaggcaa aacaatagat tttgagtcta
    15361 aaaaatataa tccctattat cttgaggact taggcgcttt tgaaattcgt tatagatttg
    15421 gtataattgc atatgcgtta tatatagttg ctttagctat aagtattata gatgccggat
    15481 ttcgaagaga caaatcggtc gccgcatttg cgggtatggc attcatggtg tttatggcgc
    15541 ttaattttaa tttgctagcg tatattacag caagaccgtt cggatttatg atttctttaa
    15601 ttttgataga aatatcggca ttcaatgatg aattcatata tattgaatag gtaagggaga
    15661 gcacagatga atttagatcg attaaagaaa atagcaaata tgatttcacc aatcataaaa
    15721 gtgataaatg cgccgttagc gtattttagt gggaaatcag attatatgga gaagggaata
    15781 ttgtggccta ctgtaacaac ctactccaat aacagtagaa aagtgattca atatacaact
    15841 ttacctaaaa acgtagacaa catggctcaa atgcaatggg ctggggaaag ttttgaggac
    15901 atatgtatag ttcttcaagg tccagtatta gaagacggtg attttacact aaataccgtt
    15961 aaaatgtata ataaatacta tcctaaagta aaacttgtag tgtctacttg gataggatta
    16021 tctgaagaga cagaatgcaa gttgcgtgaa gctggtgcag atgttgtatt atgcaagaaa
    16081 cctgaaaaaa caggtgcgta caatattaat ctacaactta cttctgcata cgaaggcgta
    16141 aaaatggcgc aaaaactggg gtgtagttat gcgctgaaaa cgcgaactga tcaaagacta
    16201 tatgcaaatg atgtactaaa gtatttccaa acattattga atatttttcc atcttcggac
    16261 tgtaaagtag tgaatcagcg attaatattt acgacttatg gaaaatcatt tagatatctt
    16321 ccgtttaatt tatgtgattt tttggtatac ggagaaacta gtgaattatt aaaattatat
    16381 ggtattcaaa gagataaccg agcatcagac tttgggaaaa ttatttatac tgaggaaaaa
    16441 gagtttaata aaaagatatt tacactacta gaaggaaaac aaggtgtatc tccatatgat
    16501 gtttttccag attttgatgc actatataaa aaatatatgt ttgcagaata ctatattgtg
    16561 tataattatt tcctggaaaa tattgcaagt aatgaatctt atggtgactt aatggatgcc
    16621 tattatagtt atttaaagaa atatgcagtt gttgctgatt cagaaaaatt gttactatat
    16681 tggccgaaat atgttcaata taatgttaag ttcgaaaatg aacttgattt ctatgcgaag
    16741 ttggattcaa aaaaatggat ggatatttat gctaattata caccttttag tcagtgatta
    16801 tatggaaagg atgaggtgaa taatgaaaat cggaatagtg actattgtta atggggcaag
    16861 ttttggtaac agattacaaa attatgcgac tcaaaaagtg ttggaaaata acggctatac
    16921 agttgagaca attaataatt gttttgacaa agaaagtacc ctatccattg ttatcaaaaa
    16981 cgctatttat acattattta agtttatacc gcatttcaaa aagtcaaaaa gtatctggaa
    17041 aagaatgtat acattttatc aatgggacaa gcagtatata gattattctc atcgtaaaat
    17101 tgatgcatct aaaaaaaaca gctttgtgag tataaagaat gattatgact atttcttggt
    17161 tggtagcgat caaatttgga atccaaaata tgcagccaat aagggatttg aacttttatc
    17221 atttgttcca aatgaaaaaa gagtttcatt atcaaccagt ttgggagttc catctatacc
    17281 aagtgattta gaaaaattat atgtgacaga gtggaataag tttaaatcaa tatcggtacg
    17341 tgaaaatcaa gcggcaaaaa taattgagga cttgacaggc acaactgcgg ctgttcacat
    17401 tgacccaact ttaatgttgg agcgttcgga atgggaagcc tttcaaaaaa aaccagacaa
    17461 tattgatgaa aattacatct tgtcgttttt cttaactaat ccgcctaagg atactgttga
    17521 tgtattagat aaggtcgcta aagatttgaa aataggtgtt ctcaccttag atgcgtcttg
    17581 ggaatatttt caagatatta ctccgaatca ttttgtttat ttgatttcac atgcaagaat
    17641 gatttataca gattcattcc actgcacagt tttttcattg ctatttggaa aaccggttgt
    17701 ggtatttgac cgttttgata gtgaaaaaat gaattctagg ttaagtacat tgttaaataa
    17761 agtaaataaa gcacattttt gggtaggaaa aaaagctgat gaagcaatga ttcgtgcaat
    17821 agcatctgaa cctgaatatg acatagataa gctgatggta tcagagaggg aatgtgtaaa
    17881 agcttatctt aaagagtatt tacagtaaaa ttttgaaatg ggatgaaaat atggagcatt
    17941 taagtgattg ttttggtaaa atgaagattg ttacgacttc atgcgcaaga gaatatttta
    18001 aggatgattt ggataaatca gagtattcat gttttgttga ttctcgagca gctatgtttt
    18061 tcgcaatggg acaagcttta gctaaaagaa ggaatgtagt tgtaatgctt gctgatgaat
    18121 tgacatcgtg ttatacggca ctaacagaat gtgcatttca acaagttgat ttaattgtgt
    18181 ttgcttttca gacagtcaga catgaaattg atttagcatc tttgaagaat tgtggttgca
    18241 atctaattaa ctgtagcgcc caagacgata ttgatagagt tgtgtccaac actaaggggt
    18301 taaatcagac aacagtaatt aaaatcaata tgaattgtga gtcggataaa gatcatatat
    18361 gtgagtatat agacctgcca gacatacctg tttttttcca cggtagctta tactcacctg
    18421 caagtaaaaa gaaatatgag cagtatggac aggtatcgaa gtatttaggc tatctcgtgg
    18481 ggggaaaaga tgcaatactc ataatttctc acaatgagtt tttaaacgat atcagtgtat
    18541 ggattaatta ttattctttt ggagaaattc aacccaaaat tattatattt gacagtccga
    18601 atgactatca atataaatgg ctgtgtgact tagaatgcag tgtagctcat tcaaccaacc
    18661 gatttttgtc tgaggattta gccttattgc aaaataacgg aatttccatt gtgttaagag
    18721 gtgataatta tgatatcgtc agttaaaaat gttcaaattt tagtatcttt attaaaacag
    18781 cataatatta aagatatagt tatctcgcca ggtagtagag attttcaatt ggtgcatagt
    18841 gtagaaacag acagtttttt tagaacctat acggttgtag atgagcgcag tgctgccttt
    18901 tttgctaatg gactttctat ggcgattgat aagcccgtgt gtgtatgttg tacttcttca
    18961 actgcctctt caaattatat ggcggcagct aaagatgctt ttgctaatgg catccaactt
    19021 gtacttctta ctgctgatag agattaccgc cgcttatatc agatggaaga tcagatgatt
    19081 gatcaggtag atatgtatgg ggcttatgtg cgttctaacg ttgatattcc tattgttaag
    19141 gattctgatg atgaatggta tgctaccaga aaaataaatg aagcaatatt ggagttaaat
    19201 catggcgtta agggtcccgt gcagattaat tatcaattaa tggatttaag tgcgccgttt
    19261 gttgagacca tgccagagta tcgtaaaatt acaagatatc aagaggatga tttactgtca
    19321 tcagtagaga tttttaaaca gaaactatta tcaaaaaaga gaataatggt tttatgtgga
    19381 cagcaggaag aaaataattt aagtgcctta ttggaagagt tctttattaa atataataca
    19441 attataatca aggataacta ttctaatata cacggtgaac actttattaa gactgttcta
    19501 gtaacagaaa gaatgagtgt aaatgcattt attgattatt gcccagattt ggtaataact
    19561 attggtaaac atgtatggtc ttttgtgaaa tatactctta gagataaaaa gcttaaattt
    19621 gagcattggc ggatatctga ggatggtaag attgttgatc cgttcaacaa gctaacatct
    19681 gtctttcagt gctcagcgga attttttatg gagactgtca ctgctggtgt gaatagcaat
    19741 aataatcttg agtattataa tctatggaag acaagattat caaaagtttg ctatccagag
    19801 ttagtctata gcaattttta tgcaatttca gaactagtaa aaaaaattcc agatagtgca
    19861 ttagttcatt ctagtatttt aaatgcggct agattgtatg actttgtatc tgatgataaa
    19921 gcattactca gttttgctaa tttaggggct gatggtattg atggttgttt accaacattt
    19981 ttaggtcagg cagaagcaga taaaactcga cctgcgtatt taatttcagg agacttgagt
    20041 ttcttttatg ctatgaatag tttatgtggt gacattccag ataatgcaca tattttcctt
    20101 attaacaatc attctggaag tgaattccat acaaattttg gtaagtttta caacggatca
    20161 ttaagtgttg ataagcatat agctgcagga catatttcaa acgcaaagga ttgggcatta
    20221 gaaaataata taaaatacat tactgcggat tctaaggaaa gtctcaaatc ggggttggat
    20281 gtatttatta atacatttga cagtcctgtt ttatttgagg tctttacaga tccggatacg
    20341 gatacgtctg ttctggaatc tttttatagt ataaataagg taatcacacc aaaaatgtat
    20401 tttagaaagg cgttagatat tataaaaaag catttacaca ttaagtagat gtttattgcg
    20461 aggtgaaaca aatatggcaa taaaatctta tattaaacgg ttattgcttt atatccgtca
    20521 tggagatccc aaaataaatt tagatgtgag ttatttatct gaaggtgcaa tgcttgctgg
    20581 taagactgtg ataattacgg gtggtgcaaa aggacttggt tttgcaattg caaaatcatt
    20641 tatagctcaa ggcgcaagcg ttattattac aggaagagac atggattcgt tgaataatgc
    20701 taaatgtcag cttggagata tgtgttctat cagggcgttt gatataactg atgctaaaat
    20761 gtatcgaacg ttttttgaag atgcatacga gacctttgga cgtattgata tactgcttaa
    20821 taatgctggg atctcgttac acgaagatgg atttatgagt gttactgaga aaacttggga
    20881 taagcaaatg gatacaaatt tgaaaggtgt ttatttcttt acacaggaat ttattaagtt
    20941 tgttaaagaa aagaatcaaa tgcaagcaaa tattattatg atgtcctcag aaagaggctt
    21001 gtgtggtgat agtattccgt atggattatc aaaggctgca attaactctt tagttgtagg
    21061 cttgtctaag aaatatattt ctgagggaat tagggttaat ggtattgctc ctggagtaac
    21121 tgcaaccgct atgactggta tttctgaaaa gggtaatttg tataatcctg caacgatcgg
    21181 ttatagatat tttctcccag aagaagttgc tcaagttgct ttgtttttgg caagtagtct
    21241 ttcaaactgt atcagtggtg aaatcatagc ctgtgacaag gggcaatatt taagtcgaaa
    21301 ttgggggtaa taacttggga atattattaa aaaaatataa tagccttagt gagcctgcaa
    21361 aagcatctat ttggtttaca ctttgtaatg tgttgcaaaa aggaattcta tttttgacta
    21421 cacctatttt tacaagaatg ctttcaactg cagaatatgg taagtatacg atttttatat
    21481 cgtggtattc tattatagca attttcacaa cgttgaattt atctgcaggt gtctataata
    21541 aaggactaat taaatacgag aataaatatg cattaacctc gtcattttta ggattatcgt
    21601 catttatttc cctttgtgca ttgatgctat accttccatt tagaacggtt ataaatgggc
    21661 tactggattt atcgacggag tttgtcatat tgattcttat tgaatcaata tttgagccgg
    21721 cttttttgct ttggtcagtt aaggaacgat ttgattacaa gtatcaaaaa ctagtactca
    21781 tcacagttct tatggctgtt ttaaatccag gtctcggtat tatattaatc ttatcatttg
    21841 gggagtatgc tatttggaga gtacgagctt atgtcgtggt aaatgttgta gtggggatgt
    21901 ttattggcat aggaatactg gctaagggta agaaattatt tgataaagag tactggacat
    21961 atgcgctcag atttaatttg ccattaatac cacattattt atcaatgaca ttgctgaatc
    22021 aggttgatcg ccttatgata aatagtatgg ttggagctag cgaggctgcg atttatagta
    22081 tcgcttacac tatatctagt atgatgaata tcataacaac agctataaac ggttctttta
    22141 ttccttttac atacaaagca attaaagatg gcgtgtatga aaaaattaaa tccgttgcta
    22201 atcaactatt agtgttgatt tttgtcttgt gttcgtttac tatgctgttc gggccagaat
    22261 tgatttgggt tgtcggagga gaaaaatata tggatgctgt ttggattatt cctccagttg
    22321 cggcatcagt atttttcatg tttttatatc cgctttttgg caatattgaa ttttactatg
    22381 aaaagacaaa ctacgtaatg tttgcatctt gtgtgggctc tatcgcaaaa attatttcaa
    22441 actatgttag tattccccgt tttggatata tttcggctgg ttacacgaca ttgatttgct
    22501 atatgttgtt ttcctttgcc cactacatgt tttataaaaa aattcttaga gaaaatggta
    22561 taaaagaaga tatgtataat attaaaaata ttatatttct ttctgtctta atgattgtgt
    22621 taactattgg tatgacaata ttatactttt ctacaattct aagatatagt attattattg
    22681 gattagttat tgtggctttt cttaaaagga cgcaaataat gaaaatcctt aaaaatataa
    22741 aaaattaaca agcaaatctt gggaatggaa cggaggcacg gtgaaatgag attattgatt
    22801 ccatctgcta agattgtacc ggaagaactt caccatcttg gaaaacttcc tgcaattatc
    22861 tatccgatta atcaaaaaat tgtatttgat tatttatatg atcaatataa agatgtatgt
    22921 tctgctatcg atattgcctg ttacgaaaag atggataagg tagcaagacg attagataag
    22981 tatattaaat ctaaaacagt aaatattatt cagcttaaag agttagggga tcttggaaga
    23041 actatatatg attctctaat aggatgtgac gagcctgtta ttattaattt tgctgatacc
    23101 attatcaatg ataatatata ttccttggaa tgtgacagct ttttctatgc tgaagactat
    23161 tatagtaata cttggacatt ctttgaagaa aaagacggag atattatttc tgttttagat
    23221 aagaacgagt taaaagaaga tgatggaaag aagcacaaac tgttttctgg tgtatttcaa
    23281 attatggatg cccagtattt tagagagtgt ttgcgtaaag ctttgatgtc aaatgtagta
    23341 aatgtgaata gtttttatca agctttacaa gagtatagca aacgatatga atttctctct
    23401 attaaaacaa ataattggtt tgacattgga catgcagata aatattataa ttccaaattg
    23461 gaagttaagg caagagaatt taaccacatt tcaattgata aagatcgtag catcctgaga
    23521 aaaattagtg aagatgttga aaaatttatc ggagaaatta agtggtatct taagttgcca
    23581 gcacaggtag aatatgtgag acctagaata ttcgaatatt ctacttcgta tattaatcca
    23641 tatgtaagta tggaatacta ttcgtatcat actgttcacg agttatttct ctatagtgac
    23701 ttaacaaaaa aacaatggat agatatcttt aatagaatac gatttgtatg ctcagacttt
    23761 aagagatact ctgtttcagg ggataatatt caaaagtcat tgaaagatat gtatctcgat
    23821 aaaacatttc agagattcaa taagctcaga aaggaccccc ggttcacaga attcttttct
    23881 tctgatattc aaataaatgg agtcagatat aaatctttgg accagataga agctttattg
    23941 agcgtaagtg ttccaagaga attgtttgac attacgcaat ttaatattat tcatggtgac
    24001 ttatgctttg ccaatattat ggtagataac acattttcgt tcattaaagt catagatccg
    24061 cgaggtaagt ttggagattt tgatatttat ggtgattata gatatgaact ggcaaaattg
    24121 tttcatagtg ttgatggaaa atatgacttt ataattaagg acttgtttac aataaaatat
    24181 gatccaaaga aggcaatcat agactatatt gttcaagatc gtaaacgaga ttatgattta
    24241 tatgaagtat tttactctgt cttcaaagat gaaataggtt ctgatttgaa aaaaattgaa
    24301 cttattgagg ctttgctgtt tttaagtatg attcctttgc atggagaaag cttaaaccat
    24361 cagatggcta tgttagcaac tggtttggaa attttaggac gagttgtccc ggatatttat
    24421 tgttaatgct ttgagctatt gtttttctat ttgatcagtg taaagccggg catataaatt
    24481 gcctggctaa aataaaggag atgtcttagt tatatgttta aagattacgc atttgttttt
    24541 gatattgatg gaactttgtg ccccatcaaa aagaaagatg agaaatatga agatttagtt
    24601 ccgtatgcta atatggtgga gaagttgcga tactataagg agaacggagc aaagattaca
    24661 ctgttcacat ctcgcaatat gaattcttat catggtaatt taggtgtgat caatgcaaat
    24721 actgcaaaaa tcttgttggc ttggctagat aagtgggaga ttccgtatga tgaaattctt
    24781 tatggaaagc cttggccagg ccataaaggg ttttatgttg atgatcgcac agttcgtccg
    24841 gatgaatttt tatcgtgtac cctggatcag ctcgatgaga tttgcaaaaa atccaaattg
    24901 aaatctgagt aaaggagact ttataaagtg aataagatga cggttattat tacaatggct
    24961 ggtcttggca gtcgctttcg taaagttggc tacactgtgc ccaaatttat gattgaagca
    25021 aaaggtaaaa ccttatttga ttggtcctta gacagcttgc ttgattataa ttcacatgta
    25081 gaaaagtatg tttttgttgt gcgtaaggaa gatgatgcta ctgtttttat caaagaacat
    25141 tgcagtctgt atggaattga aaatgtcgag gtagttgaaa ttgactatat gactgatgga
    25201 caagccacta catgtatgct tgcaattcct tattgcgcac ctgataatgc aattatggtt
    25261 tataacatag atacatatgt tgagccaggt gagatgaaat acgttgatat ttctggagaa
    25321 ggacatattc cgtgtttcca tgcggacggt gatcattgga gttttgccaa gttgaacgaa
    25381 tatggtgatg tagtagaagt aagagaaaaa gttagaattt ctaacaattg tactttaggt
    25441 gcatattatt tttcttctgc aaaattatat gcatcactct acgaagaata ttatgcagat
    25501 gaaaggcatc tggaaaagaa tgagaaatat attgcgccgc tatataatta tatgatagag
    25561 aagggcatga aggtaaccat tagtatagta gataaatcaa aagttcacgt actcggtact
    25621 ccagaagagc tcgatgtgtt cttaaatgaa tagggaaaat ataatcatag aaaatgttaa
    25681 ttataaagct gcgtgtgtgg gggagtacta ttcgatagat attctaaaaa tactaatggc
    25741 tattttagtt gttgttcgtc atttaggtca aaactattta gctccagatt aagcatttag
    25801 tattggtatt gttgcaggac tgagtacggt tgccgttcct acttttttca tcatcagttc
    25861 ctttttgttg tgtagtggtg aagttacatc cgctaaatta tctaaacaaa tctacagagt
    25921 acttaaaatt tacattattt ggtctatatt atatattcca ttagtattaa agaattgggt
    25981 acagtcagat tttagctgga aaacagatgt attattgtat atcagagatt ttctgtttat
    26041 tggtagttac tatcacctgt ggttcttgcc tgcactggct tttgctctat ggttagtacg
    26101 caaaagccag gtttctaaaa taaagtttct cagtggtttg ttgctatgcg tagtaggttt
    26161 agcatttgaa tcttattggt ttatattatc tgggaatgat tccatcgagt atattagata
    26221 ttgttataaa agcgtgtttg taacaactcg taatggatta tttataggtg taccatgcgt
    26281 cattattggg caacacttag ccttccacaa aaacactata cttaataagg tctttaaata
    26341 ccgtaatttt atcttatgtg ctgttttagc tataggatgc ttattagttg gtgaaagttt
    26401 catcataaat caaatagctt tgcgagaagt caataatttg ttaatatttt ccattccatt
    26461 agcactggta gttgtatcag tatcactgag cctaaagata gtacatttat aaaaataaca
    26521 gtacatctgc gaagaattag tacgttatta ttttgtttac atccgtatat aatagctgct
    26581 ttaaatttta ttttcccaaa attggggatt acaaattcat taatagaaat gacttgtgga
    26641 atgataataa ttttaatttc tacagttttt gtgtatgcgt gtagtgtgaa atttaccttg
    26701 ctgaaaaaat tatattagat tagtaactgg tacatgtaaa tttgttgaaa ttatagcagc
    26761 atagagatag gaattctgtt gagttttatt ttcgctggcc gaggttattc atgttagagt
    26821 gggtacctcc ttttacgaaa ccttcttgat ggtactcatt tagcgcatga tgaaaggaga
    26881 gtttatgaag aaaatcatat cttctatttt ggttaatgtg ttatctgcat tgtatcaaat
    26941 atttgggttt cgattttaat tgcagttttg gctatgtttt tatacttgtt tgcgatggct
    27001 gaggagaaat caggattagg tttgaaaaaa tcttttcttg tctggattcg gtatttcaga
    27061 aaatcaagct catttagaaa aatgtttttg cttgtgtttt ttacaaatat gattcttttt
    27121 agaacactga tggatagata tgtttggcta aatcctttgt ctaatgtgtt tggtagttgg
    27181 tggatttact ctgtgaatga aacgacaggg gagattagat taactacaga atgttttgaa
    27241 aatgttattc tgtttattcc atttataatt ctagtaatgt ggtataaggc ttcagaaaaa
    27301 gattttggaa aaatttatca gagattataa aatttgtttt tttatgttcg tgtcttatag
    27361 agtttttgca gttattttta cacatagaga cattccaatt gtcagattta ttttataata
    27421 ctttgggtgg cggcattagt ggggttatat attatttgag ctgatatatt catcctaacc
    27481 ttaaaaataa atgagcagaa ttttaaaaga ttggagagat tctatggatc ataatgcaaa
    27541 ttattatcat tggcttacaa atgccaatgc agaaattgta gaggaactgc ggtcatattc
    27601 cgagaaggac attgaggact ccttctataa aaatctgtcc tttggtaccg gtggtctgcg
    27661 tggcaccatt ggtgcaggca ctaatcgtat gaacgtacac accgtaggta aggcaagcca
    27721 gggactgtca gactatctga ataagaccta tgaaacccct tctgtcgtcg tgggctatga
    27781 ttcccgaatc aagtccgatg tatttgcaaa ggttgccgcg gacatctttg ctgcaaacgg
    27841 tattcaggtg catctgtggc cggagctgct gcctgtgcct accgtatcct ttgctatccg
    27901 ttatctgaag gcttctgccg gtgttatgat caccgcatcc cataatcctt ccaagtataa
    27961 cggatataag gtctatggcg caggcggctg ccagatcacc accgaggctg ccgctgagat
    28021 tctggctgaa attgaaaagc tggatatttt tgcagatgtg aaaatgggcg gcgacgcttc
    28081 cagaatcgct tctatccagc cagaggttct gactgctttc attgaagaag taaagggcca
    28141 gtcggttctg tttggcgaag aagtggacaa gaatgttgct atcgtgtatt ctcctttgaa
    28201 tggtaccggt ctggtgcctg ttacccgtac tctggcagaa atgggctaca gcaatgtgac
    28261 cgttgtcgaa gagcagcgtc tgccagacgg taatttcccg acctgtcctt atccgaatcc
    28321 ggaaattaat gaagctatgt ctctgggcat ggagtatgcc aagaagtata atgctgatct
    28381 gctgctggct accgaccctg actgcgaccg tgtgggtatc gccgtgaaga atgcagaagg
    28441 ggattatgtc ctgctgtccg gtaacgaaac tggtctgttg cttctggact acatatgctc
    28501 tcagagaatt aagcacggca agatgcccac tgaccctgtg atggtcaaga ccatcgtgac
    28561 tatggatctg ggcgagcgga tcgcttccaa ctatggcgtg cgtactgtcg atgtgttgac
    28621 cggcttcaag ttcatcggcg aacagattgg tatgctggaa aaggcaggca aggtggacag
    28681 ctatattttc ggctttgagg aatcctacgg ctatctatcc ggcagctatg tccgtgacaa
    28741 ggatggtgtc aacgccgctt atctgatctg cgagatgttc tcttactaca agactcaggg
    28801 tatcagtctg tttgataagc tgaacgagat ttatgctaag tatggctact gtttgaacac
    28861 cctgcattcc tttgagtttg agggtgcggc aggttttacc aagatgcaga aaattatggt
    28921 tgaattccat aaaggtcttg atatgattgg aggtaagaag gtcattgaaa ccttggatta
    28981 cagcacggga ctgaatggcc tgccgaagtc tgatgttctc aaatatctgc tggagggcaa
    29041 ctgctctgta gtggttcggc cttccggcac tgagccgaag ctgaagacct atatcagcgt
    29101 tagcgcagaa agcaaggaag ctgccgaagt aatggaagct gttatggctg ctgaactggc
    29161 tgaaatgttt aagtaatact atgaaaaaga tctgagtgtc aatgtccgaa gtagcaacat
    29221 ctatgtttaa taaaaatttc ctgctttacg gttctgttta cataattgag gtaaaggggc
    29281 cgactgtgtg gatcgaaaag gcaaagaagt gttaacagag acacagcagc ctgatgaagc
    29341 accgatcaaa gcagtaaggg agaaataaga gatattagag ttttaataat gtattcagca
    29401 atagagatga aaggagtaga atatgaataa aactattgaa ataataaaat gagggggaaa
    29461 gaaataaacg tgatattatt agttttgaga aggcgttttc aatattcgct attgtattga
    29521 tgtactattt tcagcaatcg tatttgccag caatactgaa caaagcaata tctattggtg
    29581 atacaggagt gcatatattc ttcttttgct caggttttgg gctatatctg tcatatttaa
    29641 aaaagcctat tacattgggt gaatttttac agaaacgatt tatcaagatt tatattccgt
    29701 atattatcgt aattacggta tcagtgttac taccttatat gacacaagat ttaaatgctg
    29761 caaaagtata tttgtctcat gttttgttat ttaaaatttt tctaccagta tatgaggagt
    29821 cactgggtcc ctttggttta tttcgacaat tattcagttc tatttcttat tcataccaat
    29881 tgtaaaacta tagagaaaaa taggaatgaa atgattgctt gttgcaagct gagttattag
    29941 tatctgggct attatgatgt ttcatacagg atatggaagc atacgagttc ttgggagctg
    30001 ctttgcgcaa tatatttggg aatttacttt cggcatgttt ggttgcagag tatttagtga
    30061 aaagaaaaat agtaagattt aataatatat tcgtgattat ggcgtccatt gttggaattg
    30121 gttttgctgg tatatcgaaa attattggtg gactgatgga gtctattaat gatatttttg
    30181 cattcttcgg ttacggtgca attgcaattt taatgtatca agttattcca tttagaaaga
    30241 taatgcctag gatttcaaga tactcatatg atatatatct actccatatt cttgtattta
    30301 gtacgattca tcaaattatc cctaacttgg ttttggcggc atttgtttcc attcctataa
    30361 cgttggtgtt gtcatattat tatagtatta tgttatatag acttaaatta aaatgatagc
    30421 ataattgtcg cctctaccgg gcggttgcca tcctgattaa cagcctccac gcggcggatg
    30481 gtgggcactt aggtagttcg taacctagtg gtagatggtt ggtaaaaagg agataaaact
    30541 aaatgattac acccgtggtg ctagttaatt ttaatatcct aaagaatatc tcaaagttcc
    30601 ttcaaaacgt cgttgtgctc gacttaatag aacactgtaa gccagtaata tgctttcaaa
    30661 tctactctct agccctttaa cagaacgtga gttgaaattt tgacaaccta atttttct
//
LOCUS       DAIGSZ010000034        30475 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.034, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000034 DAIGSZ010000000
VERSION     DAIGSZ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.034"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            133..3660
                     /locus_tag="NOB31_001573"
     CDS             133..3660
                     /locus_tag="NOB31_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HCI0973783.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNDPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="NOB31_001574"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="NOB31_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HCI0973784.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="NOB31_001575"
     CDS             7448..7789
                     /locus_tag="NOB31_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0973785.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="NOB31_001576"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="NOB31_001576"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HCI0973786.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="NOB31_001577"
     CDS             9146..11566
                     /locus_tag="NOB31_001577"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HCI0973787.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="NOB31_001578"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="NOB31_001578"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HCI0973788.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="NOB31_001579"
     CDS             13000..13737
                     /locus_tag="NOB31_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI0973789.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="NOB31_001580"
     CDS             13751..14566
                     /locus_tag="NOB31_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCI0973790.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="NOB31_001581"
     CDS             14579..15226
                     /locus_tag="NOB31_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI0973791.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="NOB31_001582"
     CDS             15242..15898
                     /locus_tag="NOB31_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCI0973792.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="NOB31_001583"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="NOB31_001583"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HCI0973793.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="NOB31_001584"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="NOB31_001584"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HCI0973794.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="NOB31_001585"
     CDS             18240..18758
                     /locus_tag="NOB31_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI0973795.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="NOB31_001586"
     CDS             18865..19365
                     /locus_tag="NOB31_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0973796.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="NOB31_001587"
     CDS             complement(19645..20565)
                     /locus_tag="NOB31_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCI0973797.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="NOB31_001588"
     CDS             20730..21743
                     /locus_tag="NOB31_001588"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HCI0973798.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="NOB31_001589"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="NOB31_001589"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HCI0973799.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="NOB31_001590"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="NOB31_001590"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCI0973800.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="NOB31_001591"
     CDS             complement(23383..24144)
                     /locus_tag="NOB31_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0973801.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="NOB31_001592"
     CDS             24333..25427
                     /locus_tag="NOB31_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI0973802.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25513..26472)
                     /locus_tag="NOB31_001593"
     CDS             complement(25513..26472)
                     /locus_tag="NOB31_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HCI0973803.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            26658..27593
                     /locus_tag="NOB31_001594"
     CDS             26658..27593
                     /locus_tag="NOB31_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0973804.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            complement(27678..28688)
                     /gene="gap"
                     /locus_tag="NOB31_001595"
     CDS             complement(27678..28688)
                     /gene="gap"
                     /locus_tag="NOB31_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCI0973805.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            28982..30289
                     /gene="obgE"
                     /locus_tag="NOB31_001596"
     CDS             28982..30289
                     /gene="obgE"
                     /locus_tag="NOB31_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HCI0973806.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
BASE COUNT         9982 a         5300 c         6457 g         8736 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgatcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattgcttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
    25501 ggttatgatt tgtcaaatta agctagaata aaatgcttct tgtacatagc tcaaaaatat
    25561 ttcgattggt gttctgtaat tcaatgattt tcttggaata tgattacgtt gattgctgac
    25621 actggaaata aatgtctgat tcacttttct aaaatccatt gatttcggca gtccattacg
    25681 acgcagaatc ccgttagaat tctcgtttaa tgggcgttga gaaggtgttc cagggtccgc
    25741 aaaatatata tcaatatcat gttggttact aatggctttc cagttagaaa attcttttcc
    25801 acagtcaaac gtaatagatt taaagaagtt tttagggaag cgagaaaacc attgattaag
    25861 ggcagtttca atatctaatg ccttacggcc gttgggttta atcgtgataa tgactttaga
    25921 taatctttca actaaagtaa tgacggcact tttatgatga atgccaacga tcgtatcacc
    25981 ttcaaggtga ccaaactcag aattgaaatc aggataatta tcaggtcgat catggattga
    26041 gcgctgatac tgttgttttc cccgtttttc ctgatggcca ttgggttttc ttttaccttt
    26101 catcggtagt gtgtcaatat caaatattcc tttagaaaat aaacgataaa gtgttctcat
    26161 accgcatgaa acagaccttt cttttcgccc gataatgacg tcaggcgtcc aaccaagagt
    26221 gactttctct ttaatgtaat ctacttcatg agcaggtaat tgaatgactt ttctaccaca
    26281 ttttttctta ttttctttat actggtgcca ataatcaaga gcagtcttgc cttgcttgaa
    26341 cttattgact acattataaa tagtttgtat agcacgtccc attcggttag cgatttcaac
    26401 cggcttatta tgttgaagat aatatgattc tatcattgtc agttcgtcta tggtaagatg
    26461 tttgtaggtc atttatggtt acactccttt gttttctttc gtcggaaata caatttgagt
    26521 gtaccataaa tgccttttta tttttctaac ttaattttac aattcgcggg ttataaaaat
    26581 gaacattgca tagtagagat tctttgatta tactaattca aggttatatg aaaaaagaga
    26641 aatgagatgg atgatttatg aaactttgga tgaaaatcct tttaggcgtc gctttagctc
    26701 tgattgttgc gttagtgttt gcagggaatt atttttataa ttatgctgtt gtgccttctg
    26761 agaaagactt tttagacgaa gatacacctg gtacaacaca gacatccaaa gaaacggatg
    26821 cacataaatg gtttagttca aaagaaaacc gaagcgattg gaccatcact tcaaaagacg
    26881 gtctgaaatt atcagcgatt tatcttcctg ctgaaacgaa aagtgaaaaa acagctcttg
    26941 tggctcatgg ctatatggga aacgctgaaa cgatgaccaa ttacgcaaag atgtttcatg
    27001 atatgggtta caatgtcctt gttcctgatg caagaggaca tggaaaaagc gaaggggatt
    27061 acattggatt tggatggcca gagcgtaaag actatgtaca gtggataaac aaagtgctag
    27121 aaaacaatgg aaaatcgcaa gaaatcgttc tatacggtgt cagcatggga gcagcaacag
    27181 ttatgatgac tagcggagaa aaactaccag ataatgtgaa agcaatcatt gaagattgcg
    27241 gttattcttc cgttcatgat gagcttgctt atcagctaga cgatatgttt agtcttccag
    27301 catttccgct tatgcaagta acgagtctag tgacaaaagt ccgtgctggc tactttttcg
    27361 gtgaagcaaa tgcagtggaa caattgaaga aaaaccagcg cccaatgctc tttatacatg
    27421 gagacgaaga tacatttgta ccatttgaaa tgttagataa ggtctatcgt gcaacgaagg
    27481 gaccaaaaga aaagtatgtt gtaaaaggag ccgagcatgc ggaagcatac aagacagatc
    27541 ctgaaaaata tcagcaagta gtccaacaat ttttaagcca atatgttcat tgaacgagtt
    27601 taaaagtagg ggatgaaaag aaagaagcct ttgactggat ccagtcaaag gcttctttta
    27661 tcgattgatc tatcaaatta caagttagcg aatttttcta gtaagcgaat catttggcaa
    27721 gtaaatccat actcattgtc ataccatgca acagttttaa caagttggaa atcaccagca
    27781 gttgttactt ctgtttgcgt tgggtcaaag atcgaacctt gagttgttcc aatgacatcg
    27841 ctagaaacga tttgacggtc atcatacccg aatgaaggat tgtcaactgt gtgttttttg
    27901 attgcttcgt ttacttgatc agcagttact tttgttttca atactgaaac caattcagtt
    27961 aatgaaccat caacgactgg aacacgttgt gcgtgtcctt gtaattttcc ttgtagctca
    28021 gggataacta agccgattgc tttcgcagca ccagtagaat gtgggatagt attgtcagca
    28081 gctgaacgag cagcacgcaa attaccgcct tttacaggtc catctaagag catttgtgtg
    28141 gaagtgtagg catgaactgt tgtcattgta ccaacttcga tcccaaattc attatttaag
    28201 aaataagcca taggtgctaa acagtttgtt gtacatgaac ctgctgagat gattttgtcg
    28261 ttttcatcta atgtatcatc attgacgtta tagacgatgg ttttcatagc accagctggg
    28321 gcagaaataa ctactcgttt gacaccagca tctaaatgcg cttttgcttt ttcttcagat
    28381 gtataaaaac cagtacattc tagtacgata tctacaccgt tttcttttgc ccaagggatt
    28441 ttgcttgcgt cgggttctgc ataaacacga gttgcttcgc catccactac gattgagtct
    28501 tctgttgcag taactgtgcc aggataagta ccatgagtag agtcaaattg caataattgt
    28561 gctaacatag ttggacttgt taagtcgttg attgctacta cttcaatatc atctgagact
    28621 tctttgatgc ggcggaaagc cagacggcca atacgcccaa atccgttaat acctactttt
    28681 actgtcatat caaaagttcc tcctttatta ggggtgctgt gaaacggcat cctcaattaa
    28741 tacaattaat acactgttat tctgctacgc aaagaatatt ttgtcaaaaa attatacttg
    28801 gtagcagaaa aaaggttgga aaccttacca aatgataaaa aaagaagaag gtaaacaatc
    28861 tttttgctga aatgatagac aaaatcagat ttcaccgata aaataagtaa gacttttgtt
    28921 tattgtggaa attcaggcag tcaaataaat aaatgaataa taggaggact taattatgtc
    28981 catgttttta gatcaagtaa cgatcgatgt gaaagctggc aagggcggag acggaatggt
    29041 tgcatttcgt cgcgaaaaat acgttcctga cggcggaccg gctggcggag acggtggtcg
    29101 tggcggcgat gtcatcttga tcgtcgatga agggttacgt acattgatgg attttcggtt
    29161 caatcgccat ttcaaagcgc agccaggtga aaatgggatg agtaaaggga tgcacggtcg
    29221 tggttcagaa gatacctatg ttaaagtacc acaaggaacc actgtccgag atgcggagac
    29281 tggtgctctt ttaggagatt taattgaaaa tggtcaaaca ctagttgtgg caaaaggtgg
    29341 acgcggtgga cgagggaata tccgttttgc ctctcctcgg aatcctgcac cggaaattgc
    29401 tgaaaacggt gaaccaggac aagagcgaaa aatcgaacta gaattgaaag tattggcaga
    29461 cgttggactt gtaggttttc catctgtcgg gaaatcgact ttactatccg ttatttcatc
    29521 tgctcgtcca aaaatcggcg cttatcattt cacgacgctc gtacctaatc taggaatggt
    29581 tactacaagt gatggcagaa gttttgccgc agcagacttg ccaggcttga ttgaaggagc
    29641 ttcgcaaggt gttgggctgg gtacacaatt ccttcgtcat atcgaaagaa cacgagtaat
    29701 tttacatgtg atcgatatga gtgggatgga aggacgagat ccttatgaag actatcttgc
    29761 catcaacaaa gaattatcta cttataactt acgcttgcta gagcgtccgc aaatcatcgt
    29821 ggcaaacaaa atggatatgc cggatgcacc ggaaaatcta gtgaaattca aagaacagct
    29881 gaacaaggaa aaagaagatg aatttgctga tgacatccca gtatttccaa tttctggagt
    29941 gactcgacaa ggattggacg cgttattgaa tgctacagca gatttgttag aagtaacgcc
    30001 agaattccca ttgtacgaag aagaactgga agaagaaact gtacactatg gattcaatcc
    30061 agaaggtcct gagttccaaa tcgatcgtga ttcagatgca acgtggatct tatctggtga
    30121 gaagatcgaa aaattattcc aaatgacgaa tttcgatcat gatgaaacag tgatgcgttt
    30181 tgctcgtcaa ttacgtggta tgggtgtgga tgaagctctt cgggcacgcg gtgcgaaaga
    30241 tggcgacctt gtacgtatcg gtgagtttga atttgaattt gtcgaatagg caagcaaata
    30301 aaaacaaata ccaaaaaata tagattcaga tttaagggag gttgtgacag aagtgatcag
    30361 cttcaagaac gccgtttatt cggaaaaagg agctgtgata cgacttttgt cacagcccta
    30421 ttttattgga aaaaaagagt gcttttcttt tcttattttt caattaaagg taaaa
//
LOCUS       DAIGSZ010000035        29604 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.035, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000035 DAIGSZ010000000
VERSION     DAIGSZ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.035"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            240..551
                     /locus_tag="NOB31_001597"
     CDS             240..551
                     /locus_tag="NOB31_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HCI0973807.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            548..766
                     /locus_tag="NOB31_001598"
     CDS             548..766
                     /locus_tag="NOB31_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HCI0973808.1"
                     /translation="MISLTIFWCVIGGLLAMLGAYLIYESAKGKKYTAVGIILFVVGI
                     LVAIGAEINLYLNGTTEELMWFLLWTRR"
     gene            779..1060
                     /locus_tag="NOB31_001599"
     CDS             779..1060
                     /locus_tag="NOB31_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973809.1"
                     /translation="MGDMGEYWKDIKPHLKERRKQHVRKMGNSATKNIETLGFEFTHY
                     PNNHQFAINTHNGIIDYWGTTGTWIERKTKKRGKGIRSLRKYINQEDSK"
     gene            1057..1383
                     /locus_tag="NOB31_001600"
     CDS             1057..1383
                     /locus_tag="NOB31_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973810.1"
                     /translation="MNYTQQELTDLCPKHVAEFINNEVLPKYADGLNTAENVTDFMIN
                     DAIDRLIFLEIDCIAYYRLHAEVALIDPYIALSQNRKILVAYIDTKQILEGRDVEIEI
                     DEEEVG"
     gene            1380..1577
                     /locus_tag="NOB31_001601"
     CDS             1380..1577
                     /locus_tag="NOB31_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973811.1"
                     /translation="MKAYTIKFYGNKTYVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            1574..1783
                     /locus_tag="NOB31_001602"
     CDS             1574..1783
                     /locus_tag="NOB31_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973812.1"
                     /translation="MKIYVVKFGNKFYRSDERSIGANTLFIVDILQSARWFDSLEEAN
                     QVSRRLGGLTQVYELVTVDHEEVER"
     gene            1780..2067
                     /locus_tag="NOB31_001603"
     CDS             1780..2067
                     /locus_tag="NOB31_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973813.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKKRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMKAI"
     gene            2660..3127
                     /locus_tag="NOB31_001604"
     CDS             2660..3127
                     /locus_tag="NOB31_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HCI0973814.1"
                     /translation="MVLFDVKKYETPEAKDVDMDRTKHNVGVFLSAYLSARCRIGQPR
                     EPKVTASYSLVPPSTANNTFEAERMMIEREEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            3426..3767
                     /locus_tag="NOB31_001605"
     CDS             3426..3767
                     /locus_tag="NOB31_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973815.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDPRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(3760..3951)
                     /locus_tag="NOB31_001606"
     CDS             complement(3760..3951)
                     /locus_tag="NOB31_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HCI0973816.1"
                     /translation="MVKNLYFVIREATNGQYYFVIKSDNNEVVATSETYLTKYSAEQT
                     INSIKNGITKDSQVIDVTK"
     gene            4301..4513
                     /locus_tag="NOB31_001607"
     CDS             4301..4513
                     /locus_tag="NOB31_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973817.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQAKYFYDQL
                     ILQGFNDAQAMEFMMRTFSASNQQKE"
     gene            4520..4744
                     /locus_tag="NOB31_001608"
     CDS             4520..4744
                     /locus_tag="NOB31_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973818.1"
                     /translation="MRNYWYVSLSNKYPQPNADDPIRVVQSVQIKKKYSIIEMTREAT
                     PKEIDKYNLRYCGHGYFSEQNIQTNIERYC"
     gene            4771..5304
                     /locus_tag="NOB31_001609"
     CDS             4771..5304
                     /locus_tag="NOB31_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HCI0973819.1"
                     /translation="MVNLTPKQKAFADEYIKNGGNATQAAIKAGYSKRSARVIGKENL
                     TKPNIIQYINERLNPIEKKRKLSAEDALNELIDIWQGEVQISVSKQIDRLEKNKVIKH
                     MQYEYTPDLESKLKALDLYLKYKSLLSQTQLEKAQTEIKLMQAKLEQLQINSERSTEE
                     KLDELLEKISGELDGTS"
     gene            5291..6535
                     /locus_tag="NOB31_001610"
     CDS             5291..6535
                     /locus_tag="NOB31_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HCI0973820.1"
                     /translation="MALVDIYNPKQIDVLNKTIKNDWFITLLHGAKRSGKTKINNDLF
                     LFELRRVRKIADEEDIKEPMYILAGVSSATIQKNILQELYNMYSIEPKFDKHGNFKLF
                     GVKVVQAYTGNIGGVGAIRGMTAYGAYINEASLARQEVFAEIVSRCSGTGARILADTN
                     PDNPEHWLKKEYIDNSSKNIQSFHFELDDNTFLSERYRNNIKESTPSGMFYDRDIKGL
                     WVSAEGVVYRDFDASKHYIQSKDLPPLSNFYCGVDWGYEHWGSIVVIGETDDGTAYLI
                     EEHATQFEEIDYWVDVAKGIQERYGLRVPFYCDSARPEHVARFVREKINAKNAHKARL
                     SGVEEVAKRFKQDKLFICQDRVMKFRDEIYQYIWDKKKGEPIKEYDDVLDSVRYAIYT
                     HELLKKPKVNVNEKIKRIKRMF"
     gene            6548..8047
                     /locus_tag="NOB31_001611"
     CDS             6548..8047
                     /locus_tag="NOB31_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI0973821.1"
                     /translation="MDKVNEFEYGADIHYSNDVNTNYVKFSVDSNLHYRFSSAEDLLN
                     DLDTLAAMIKHHHEYQVKRLSVLDDYYKARNTNIMDNRRRREKEKADHRSAHNFGKVL
                     CTFDVGYNTGNPIKVQIEDTNQQKEIEEFNTNNDIDGLNAELWLDMDKYGRAYEIIYR
                     DSDDTDYVDLANVFETFVVYDTTVKREPILAVRYPKTRFNKDADKQYIQPIVYTKEKS
                     ITYDETTLTAIELKNPQDEPHEYKEVPITEYSPNRFRMGLYEDVLSLIDLYDAGQSDT
                     ANYMTDLNDALLVISGDIEAAGLSTEDAIKQKEANMLLLESGTDVNGNKTSVTAGYIY
                     KQYDVNGVEAYKYRVRKDIHEISMVPDLTDDNFSGVQSGEAMKYKLFGFEQMTATKQR
                     LFKKGLMRRYRLLFSLKSSISEMDNSDLKGLRVIFTPNLPKAILEELKSLVDAGAELS
                     QETILGLASFVPDVQAELKRVNKETQKQIGIFDSDGEEVINNKKDETGG"
     gene            8052..8978
                     /locus_tag="NOB31_001612"
     CDS             8052..8978
                     /locus_tag="NOB31_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HCI0973822.1"
                     /translation="MNSQEYWIKREKEWQKQQIKDDKKRMAEIKSRMQYAQDAIQKEI
                     DAQWDSFSNGQKITRSEAMKRASEMDVKAFARKAKKYVKEKDFSPTANQELKLYNLTM
                     RVNRLELLKANIGLELISLFNELDKYFSNELTKAGLAELKRQAGILEMTIASSGYAKL
                     IELVINSSFLSDDVSFSDRLWMYQSELKSELDRLLVRSITMGKNPKQLASKLAEYLTA
                     EGRENTKFNTQRLMVTETTRVQVGIQERSYRDAGITQYIYIAEPTACKLCIPLNNQVF
                     DVADMQPGSNAPNMHPFCRCSTAPYIERISSR"
     gene            9105..9707
                     /locus_tag="NOB31_001613"
     CDS             9105..9707
                     /locus_tag="NOB31_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HCI0973823.1"
                     /translation="MKKRLFMPMNLQFFSEPGDGGSGDEGQQGNLPAGSQETPPEAKE
                     ENNTGKTFSRDEVAKMIAAETNKAKAAWEKELAAKKEEAKKLAKMNAEEKLQHELEQK
                     EAEIAELKRGQALSEMTKEASKMLTDANLPHDDDLLGLIVSDDADATKQAVAVITNFA
                     SLIKRENARQTPPNEGGQFTASKNTKETVAKLAAKNRIIK"
     gene            9720..10643
                     /locus_tag="NOB31_001614"
     CDS             9720..10643
                     /locus_tag="NOB31_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCI0973824.1"
                     /translation="MKKKQLLPMNLQMFAQTWDPDNVLVYETKEGKIPDKYNTLILSE
                     VMENSKIMQLAKYEEMTDKEKKFEYFAEGPGAYWVGEGEKIKTSKPKWMQATMTAKKL
                     GVILPVSREYLNYKLSDFFEEMQPKIAEAFYKKFDAAALLNKENPFPQSLDGSVISAG
                     NVVEGGLTYDNILALEDKLAENEFEPNAFISNRKNRTELRSAAQTVGSNVEFIYDRST
                     NTIDGLPVVDLKSLDKGTLYAGDFNYMFYGIPYNISFKISEEAQLSTLTNEDGTPVNL
                     FEQELIALRATMDVGFMIVKDEAFGKISPKA"
     gene            10661..10924
                     /locus_tag="NOB31_001615"
     CDS             10661..10924
                     /locus_tag="NOB31_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973825.1"
                     /translation="MPNQKTWTGKVGDTKTFTISAVPADASDAAAVVAATTATSSDGA
                     IATVTKNENGGFDGTIAAEGSATFTFTSGEFTTSINVTGQPAS"
     gene            10936..11265
                     /locus_tag="NOB31_001616"
     CDS             10936..11265
                     /locus_tag="NOB31_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HCI0973826.1"
                     /translation="MMIADDIKKLLKGTIDEKLEVIERRTNERMKTLLNTQEVPKEFE
                     TVVYEVSLKRFNRIGQEGMQSYSQEGLSMAFPDSDFSEYQNEIDEFKRKDQEELYKPK
                     RGRFKFV"
     gene            11262..11588
                     /locus_tag="NOB31_001617"
     CDS             11262..11588
                     /locus_tag="NOB31_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973827.1"
                     /translation="MRFTDEIIFVKRSSDSKYDPDLGEWVEGKPERTRTEANVTDIGT
                     DRSVTIFGSVEEGAKVIRTQPLFSIPTFDYIEIEGKTWQQKTARNPAYRNSLIVQEVV
                     LDEGTT"
     gene            11572..11910
                     /locus_tag="NOB31_001618"
     CDS             11572..11910
                     /locus_tag="NOB31_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HCI0973828.1"
                     /translation="MKAQLEYKGIDQLMRHLKKAATLNDVQKVVKSNTAEMTERMQKG
                     APVDTGYLRRSINMNLLEAGLTGIVGPTADYAPYVEYGTRFMSAQPYVRPAFNYQKVK
                     FMAEMKALVK"
     gene            11910..12302
                     /locus_tag="NOB31_001619"
     CDS             11910..12302
                     /locus_tag="NOB31_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HCI0973829.1"
                     /translation="MIKTRDQSIFDELFKISQNKLGYKTYDYKTLEDVGYPFVEFENT
                     QTIHEVNKTDIKGSVIVVLSVWGLQKKRKQLSDRASALFNEARLIEATEGYYWALNYQ
                     ASGIQVMDDTTTNTPLKRAVVTLEFRIR"
     gene            12313..12825
                     /locus_tag="NOB31_001620"
     CDS             12313..12825
                     /locus_tag="NOB31_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HCI0973830.1"
                     /translation="MEALKGIDVILLYRLLKKETQEAAWKMAFQTEHENGLSRDSDST
                     VTKDGNVQSLSPVEYDFSATSIVAKGDSHVDEMKQALLNGDIIEIWEINKAEQGTDDN
                     ANKYKATYYQAYVSEFTPSAAAEDNVELSLSFAVNGVGQDGYATLTEDQADVVQYAFK
                     DTVKATSTGA"
     gene            12871..13239
                     /locus_tag="NOB31_001621"
     CDS             12871..13239
                     /locus_tag="NOB31_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HCI0973831.1"
                     /translation="MKLKIKGKEYSFKFGTKFVRELDKVMPFVDGNMEFGMGLSAKVL
                     PELRSYNVNTLSRVLEIANRTEDESITLDELDDYIDEVKDIEKLFDEVLKELAESNAG
                     KLAVRNLNQKLKEAEKQQVE"
     gene            13293..13580
                     /locus_tag="NOB31_001622"
     CDS             13293..13580
                     /locus_tag="NOB31_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973832.1"
                     /translation="MTNISDIERMTLYEYNIRMTAAQLSWLDKEKLIHELAWANQQVQ
                     AEKKVGKKTVPVYRSFEEFFNYQKIEDSIMGVSELSKQDKKFQSLLTKANS"
     gene            13597..16716
                     /locus_tag="NOB31_001623"
     CDS             13597..16716
                     /locus_tag="NOB31_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCI0973833.1"
                     /translation="MEQFSVEALLKATDSGFVKTFKDAQDAVKTFEKNSNSMTTAVGK
                     VMQGTGAAMTKYITTPLIGVGVAAAKVGGDFEAQMSRVKAISGATGDTFEQMKQQAID
                     LGAKTAFSAKESAAGMENLASAGFSAQEIMKAMPGLLDLAAVSGGDVALASENTATAL
                     RGFGLEASEAGHVADVFARAAADTNAEVGDMGEALKYVAPVANSMGISLEETAAAIGI
                     MSDAGIKGSQAGTTLRGALSRLARPTKAMQDTMDNLGVSFYDADGKMKPLKTQVELLK
                     KAFEGLTPEQQQNALVTLYGQESLSGMMALIDKGPDSLGKLTKSLKDSDGAADDMART
                     MQDNMNSSIEQMFGAFESAAIVIQKILAPSIKKVADAISGLVEKFVSAPESTQKLVVA
                     IGAIVAAIGPLIFMIGSVIIWINRVKVAFKALSESSKLFSGLSKAMGLLTNPVFLVIA
                     AVALLVVGFIYLWNTSEDFRNFWIGLWEGIKSAVSSAVEWIQNAWKSTGEWFNNLWKS
                     IKEGADNVWTTVQEAPGKAADWIKNKWTGTKEFFSNLWSSIANSASEIWNSLKEGVIS
                     VIDDLVSSAGEKWEGFKNTISTAWKTITSKIKSGFDFILKYIGPFVSSFSDVFSNIVK
                     AITSIFAEVKNIIVNAWEIIKSLIAAPLLFIIDLITGDFEQMKEDLDLIWNTLVQSVV
                     NIWTSVKNIFTEYIGAIVNSAVSLWTGFIQSISNIWNEVVYQATMIWIDLKLFFTNLW
                     IDIKYSAIQMWINLKFSIIQTWIDTKYGAIELWNNLKQWFFQTVNNIVQTLIKSWNSL
                     KQGTIDLFNNTVQGAKDIWTSFKSWIGDLITGTKDNIIQGWENLKQGTIDTFNNLVNG
                     AQEAWDNLVNAVSDTVDRVTGWFDNLKNIDLLAAGKAIMDSFLEGLQNAWKSVQDFVG
                     GIGDWIREHKGPIQYDRKLLIPAGQAIMNGLNKGLTGGFNDVQNTVGSMADFIAELFN
                     ANSDVDIAANLKNANKNIGAQVEHKINMGGSTKPAVFKINLGRQSFRLFMDDISQAMG
                     EGADINLEF"
     gene            16749..17516
                     /locus_tag="NOB31_001624"
     CDS             16749..17516
                     /locus_tag="NOB31_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HCI0973834.1"
                     /translation="MYSFKDTTINLTSSKRFLPTSAMMYDGMYLEDLIDGYQTLTVEG
                     REMLSVEVEQQEIQIGSIITNQKIPSRTLKITYKLEDRDPEKLQFKFKELLNYLYRNE
                     DVEIRFHDELDYYYYGRYTSTDTVPGDSNSIISSFNVFCADPLKYTKECVSDGYIGNP
                     IQFPITPRKIEVTLSMNNSIKITNGEQNITITDAAIKTGDVLVFDFSDEQVTVNGEDC
                     TSMIDLESDFENFYLKQGQKITSNNGKLKIFYRGATI"
     gene            17513..20344
                     /locus_tag="NOB31_001625"
     CDS             17513..20344
                     /locus_tag="NOB31_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HCI0973835.1"
                     /translation="MSETVYFFDHLQKLIKRKNTRSLIEVSQEKEISSDKSDLMKDTL
                     YVTTKYDKEIEDARYMAIRENESSFSLYRITKVSDPFETLEFTGLGFATNELDAYIIK
                     DIRPSGQPLKNVLDRLIEFTEGNWRVGHVEAMLPTVTATFYYVSVKEALKELQTLGME
                     FVFRCSLNSDGIKDKWIEVYEQIGEESNTRFVYGSKALTVVREIDRSSISTSMIGRGR
                     GEEVGDGYGRRIEFTDVEWKKSNGDPLDKPKGQNRLEDPESTQKYGIPQKDGSMRKRE
                     TVVVFDDIDDPTDLLKNTYSTLIDSARPLVQFKAEVTGGDVIGNTVTIHRYDKGYHYK
                     TRIYKTTFNRLTGQTNIELGDNLTQDVRKQTASIVNNINSLESSKMTFYESTEIGKYQ
                     DDIMRGAGDNGGSIYWVNGIEAGVSDSREIYETVYMDGPNIPRSRFFMVQNNSGISFK
                     QCKKGEWQTIQDVHNGDSTTAWTLDGTFNANFIRAGILSGILVQGVALKTFDDKDFQL
                     VAEGGELSFEKQVKSTGLDDVHGERLGSIVSTYGSKGINGFAVWKEPNYIFSINAGDG
                     GDRGNPIFQIPADVTADKRKYNLYGDGNFSEGNITIDGRLDVKELYVNGTKIDTNGGG
                     NSGGNDNGWNGQYPPEVTTDRDKRYWQIWATAIGAGFTQQAAAALLGNAQGESDANPT
                     ADEGNGAPGFGYGVWQWTDSSGATSGRVYMINLMTKAGISDDPDTITAQFKLLMWHAP
                     NGQWIATSAYPYTWTQFMNLTDINTAAQAFVANFERPRDPHPERTAWSQEWYDKFKDL
                     EIPVSKGYMKPIADPITVTSEFGWRTSPITGAQEFHNGIDLVNGNPNTPIFASADGEV
                     IVAGDANYFDWYGNWTVIKHADGMYTGYAHQSRVDVSKGQKVTAGQQIGLMGTTGPST
                     GEHLHFQFMDEFYPSSSGHFHNARDYIDF"
     gene            20319..22076
                     /locus_tag="NOB31_001626"
     CDS             20319..22076
                     /locus_tag="NOB31_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HCI0973836.1"
                     /translation="MQETTSISKGGIVMAETQHKMVLSTTEPNNGINLVRIRQGDVLT
                     QKFVVEVVEHGKLKTFEGLVPFFINTTKFGENQPVEQKVQEYSPAQARLVYTLSEPDW
                     QWGGENTAHFSFRSLNGDGTWSEQFSTQDFTYRVISGISRSQLRDSGYVWTFEDLLRK
                     FKDYMDQGKNDWEQWLEDNREILENIDPGGMIINILNEAKGDYESLADRLNQKYQVPV
                     GSSQIRETTRFFDYDTMKYVDLVPRNLNTVVNSVNNSKFNFSFITDIHADNHNLRIDG
                     VGYKDASYLRHWRAIPQFQKLGNKTDVMIYGGDNIDGGLGSLGSDIGIIDEWSARHSM
                     LGTLKRFTNAAVAGQEKPVIICKGNHDACFDPAWRKRKGMLCNADFEEYWNGLYGGVL
                     FPDKNAAIYRFDTCDFYEGGTGDKYVDGYSDTAPGAFSAKQINAFGEWLVNVPRNYHV
                     ALVGHTPLGLSKFPVRNENMISTLIEGFKSGSPVTIDWSKLGQPNDGSFGGLKTFAMN
                     TKGAGVVVGYFCGHWHEQVEGAFGTVKMILCDVGFSHTASQVDTPDELAFYKIEVDTA
                     TRKVTSKGVGRARDFTYNY"
     gene            22093..22875
                     /locus_tag="NOB31_001627"
     CDS             22093..22875
                     /locus_tag="NOB31_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973837.1"
                     /translation="MLDFQSKPNIFEEMSYEEAVKWLLRQAAIHYDGSDHDAHVLATE
                     SNAGFATPETVMQARGRWLRDYKLPQKYPNILDIPPGKYATKAGWGADNPDGIEDDSF
                     VEMMVFADHDSRKLIVAFARYSGEIYIKMTHNSEPVEGYNSLGWRRVYTTSVLFEGEL
                     RKGQSVNLPDDTFRYQTLRIHYTDGDGDFVEEVKRQRYARITKANLWNGDAGVTFIEF
                     ELTIEARKITMSNGRALDISSGNVSNPAMSNNVKITKIEGVK"
     gene            22875..25061
                     /locus_tag="NOB31_001628"
     CDS             22875..25061
                     /locus_tag="NOB31_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HCI0973838.1"
                     /translation="MAHVIKKGSIKVPTQPKDYDLQATGLVFKSYDNQIALEFNVEQQ
                     NGTPADLLGANLRLLMFIYDEVDGMITKEPIPFITKNLITESFLNGQVVYILPEAMKA
                     YNGMVEAYVYIEYPDGSTSDNLGFTFRMKRSAIDGLAQDKADYFIADFQQLLDGVKQE
                     ATDAVNAALTNVDSTIEKANQQINEFVEGATQAIDQTVDEVTEQLQATQTKIDTVSQN
                     VTSAQNNLKAVEDKMNQTNQQIGDLGKLKKMYSNSIDFGNYDYSGNPNLMSKLKSSDF
                     NVGYHGSLTSDNEKLHFTSDGTGSIIMFTRINTPQLASGKTYTLSAKVRFDEGTTGAI
                     DKLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYMSISFV
                     DRDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWLGKAPLGENIANKSVTFPIKSSA
                     YSLYQANMEEEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRYGNLEPVEGLVDTWG
                     LTFTPQKVGVNYPKRLTIIQYPQSTTGACQIDWLKIEKGDTRTPNISQFKYFGEGLKD
                     SNNPNDYSWDVTPEYTEKGLNDAVNVYDPQRVEGLKNFADGIQIAGDKVISENDCTVY
                     TLTKDNSQSFIDGYATFIKHGKEVIVNGTVKFKKAYAFGVPLDDEVPDEFVAKIVHGM
                     LTGPSGTSSVSKAMYVRKDLGTIITNSEFAANEWFTFHGNYWVGEE"
     gene            25064..25510
                     /locus_tag="NOB31_001629"
     CDS             25064..25510
                     /locus_tag="NOB31_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973839.1"
                     /translation="MKNIWKYGRTGGEYAGQVLDDMVMTVPFTDVPPLEGIRADGEPL
                     TIADQMFDPKLNQWIVLVNVLDHNDLNNLKAMYESLENENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADGLAQINSKTMLASFQNSKDIAEIKEQLNPASKGGE"
     gene            25512..25649
                     /locus_tag="NOB31_001630"
     CDS             25512..25649
                     /locus_tag="NOB31_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HCI0973840.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEAEKIINKDKSA
                     S"
     gene            25686..25979
                     /locus_tag="NOB31_001631"
     CDS             25686..25979
                     /locus_tag="NOB31_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973841.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
     gene            26002..26199
                     /locus_tag="NOB31_001632"
     CDS             26002..26199
                     /locus_tag="NOB31_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCI0973842.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            26210..27229
                     /locus_tag="NOB31_001633"
     CDS             26210..27229
                     /locus_tag="NOB31_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HCI0973843.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            27486..28133
                     /locus_tag="NOB31_001634"
     CDS             27486..28133
                     /locus_tag="NOB31_001634"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI0973844.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
     gene            28416..28489
                     /locus_tag="NOB31_001635"
     tRNA            28416..28489
                     /locus_tag="NOB31_001635"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28450..28452,aa:Ile,seq:cat)
     gene            29035..>29604
                     /locus_tag="NOB31_001636"
     CDS             29035..>29604
                     /locus_tag="NOB31_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HCI0973845.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT        10428 a         4704 c         6298 g         8174 t
ORIGIN      
        1 gatcgtttca aatttgtaga aaagtataga gagatactga atgagtattt cgaggaggac
       61 tagatgttta attcaacgtt agcgtcaatt cactttttat tctatataac gatatttgta
      121 gctatattaa ttaatgcgat aaaaagcggt tttttaacac caatcggcac aattttaaca
      181 ttagcttcat ttgttacaag ttgtattatc caacttaaat atataaagga gaatgaataa
      241 tggacgaact aatcacaaaa gtagagcagt gggctaaaga taagggattg gatcaagctg
      301 attccagcaa gcaaatgtta aaaacgatcg aagagatcgg ggaagttgcc gcttctctag
      361 ctagaaaaga tgaacatggt ttaagagacg gaattggaga tgtagtagta accttgatta
      421 ttttagctat gcaaaatgat atggatttgt acgagtgtct gaaccaagca tacaacgaaa
      481 tcaaaggacg cacaggaaaa atggtagatg gtgtattcgt gaagtcgagt gatttggagg
      541 acagcaaatg atcagcctaa caatattttg gtgtgtaatt ggcggcttac tagcgatgtt
      601 aggagcatac ctcatttacg agagtgcaaa aggcaaaaaa tatacagcag tagggattat
      661 tttgtttgtt gtcggaattt tagttgcgat tggtgcagaa ataaatcttt atttaaacgg
      721 tacgacagaa gagttgatgt ggtttttatt gtggacaagg agataggagg acagcgaaat
      781 gggcgatatg ggcgaatact ggaaagatat taaaccgcat ctaaaagaac gtagaaaaca
      841 acatgtcaga aagatgggca attcagcaac taaaaatatt gaaaccttgg gatttgaatt
      901 tactcattat ccaaacaatc atcaatttgc aattaatacc cataatggaa ttattgacta
      961 ctggggaact acaggaacgt ggattgagcg caaaacaaaa aaacgtggta aagggatacg
     1021 tagtttgagg aaatatatta atcaggagga cagcaaatga actatacaca acaagaactg
     1081 actgatttat gtccaaaaca tgtagctgag ttcatcaata atgaagtcct gcctaaatat
     1141 gcagatggtt taaatacagc agaaaacgtt acagatttta tgattaatga tgctattgat
     1201 cgtttgatat ttttagaaat agattgtatt gcttattatc gtctacacgc agaagttgct
     1261 ttgattgatc cgtatattgc tttaagccaa aatcgaaaaa tactcgtagc ctatattgat
     1321 accaaacaga ttttagaagg cagagatgtc gagatagaga tcgatgagga ggaagtggga
     1381 tgaaagcata cacaatcaag ttttatggaa ataaaaccta tgtatacatc ctaagcggtc
     1441 tcagacttga ttttagaggc tattcaaaag aagacctttt agaatcctta tatggttacg
     1501 gatatttaaa tgaagatgaa ctaataagct tagagaaatt tacaaatgct tggacgattg
     1561 aggaggaagc agaatgaaga tttatgtagt aaagttcggg aataaatttt atagaagtga
     1621 tgaacgctct ataggggcta acacattatt cattgtagac atactccaaa gtgcgagatg
     1681 gtttgatagc ctcgaagaag ctaaccaagt ttcacgacga cttggtggat taacacaagt
     1741 atatgaactg gtcactgtcg atcatgagga ggtagaaaga tgaaattaaa agacggattt
     1801 tacgctagta gtcatggtat cggcggttta atgctagata tgccgacaaa gaatcctaaa
     1861 aaacgtaaga aaccaaaatt caaagtcggt gacatggttc gctgcgaagc agaagggttc
     1921 atctatccat ttcgtggata tgtagaacac gtctataatc actcagcgat cattcgtatt
     1981 gaaaacacga tggaatgtga taagtggtta gcgaaaagca aagagaattt agctgtagcg
     2041 agattggtgg atatgaaggc tatataaaca gcgaaaaaat gtacttctaa gagaaaaatt
     2101 tattttttat aaaaatagga aagtatcatt atgaaaaaga ccacagagat aaataaacct
     2161 accacataaa aaatgaatat ttcttgcgat tcaatatagg tatatttaac aatttgtaca
     2221 ataaaaaata ctataggtaa aaaagataac atgaggagct tatttgttct agagtgtttg
     2281 acaaagtaac aaaatgcgac gataccaata caaacgggaa tccaaaataa cagcatgctc
     2341 cacatagtca ctcaaccatc tcctatacgc tttattatca attagataat atcatttttc
     2401 gtaataaaga taaaaaaata agtaaggctt ctcattaaaa tataaaaaag acagccgacc
     2461 actggctgtc cttagcagaa tattgaaata gtgagccatc tgttttccgc cagatagctc
     2521 aacatgtata tgggtaacga gtgcaacctc gctacttgaa aagcttagca taagcatggg
     2581 tataaaaaaa gccggattcc tccgacctta attaataatt ctgacacaat tattatatca
     2641 taaatggagg aatcaatgga tggtactttt cgatgtaaag aagtatgaga caccagaggc
     2701 aaaagatgtg gatatggatc gcacaaaaca taatgttggt gtttttcttt cagcatatct
     2761 gtcagctaga tgtaggatag gtcaacctcg ggagcctaaa gtaacggcat cttactcctt
     2821 ggttccacct tctacagcaa ataatacatt tgaagcagaa cgaatgatga ttgagagaga
     2881 ggaagcgcaa gaagaatttg agtacttgca caaattattt gttcgtggct attcagcaat
     2941 tcagcatccg cataaacctg atgtaacaga aaggcgcaag aagatattct atgatcgtta
     3001 tatcaatggt ctgcccattt atgtaactgc tcaaaggaat aatactagcg aagaatcggt
     3061 taaagtagaa tcaaacagaa ttatcatcca atttgcttca tcgttagaac tggttgcttt
     3121 taagtagcca gtttttacac tttttatacc ctttgattac ccatttggtt tccattttat
     3181 acctttttta taccaatcac ttacctggta aatgatttat tatgatagtg tcgaaagatt
     3241 agtgataggt ctgagacaaa ataataataa aaggaacatc gttttattat tgtttcacaa
     3301 ttaagcttcg atagacagca acggaaatat taagaataag gatgtgaatt ccaactcctt
     3361 ctaaattgtt cttattatct atcatccgtt gctgtttatt aatttatgta ttggagggaa
     3421 aacgaatgga agtcgagcaa ataaagtatc aaggtatgga tcgggaacgg ttgattgata
     3481 ttattgagca acaacgttta gaattgatcc aaaaagaagc tgtatgtaaa gagtacaaaa
     3541 aacatttaga acaagtaatt gagtatcatt cagtagaaaa gtacagatca gtggtgcaaa
     3601 aaaatagagc aacgagtcct gatcctcgtc aagatgtatc gattagtatc aagacgccag
     3661 tatttaattc tgttaaatca gaaaagctag aaagtatctc aactgctttg gtagaaaaag
     3721 cagctgaaat gaactcccta gcaaatgaag ttagtcgtct tatttagtca catcgataac
     3781 ttgagagtct ttggtgattc cgttttttat agaattaatg gtttgttcag cggaatattt
     3841 agtcaagtat gtttcgctag ttgctactac ttcattgtta tcggacttaa taacgaagta
     3901 atattggcca ttagttgctt ctcttataac aaagtacaaa tttttcacca ccttttaatt
     3961 tatttcagcg gaccactcgc tgataaataa aattatacac ttagtattta ttttcacaat
     4021 attaatttgt cactgtggcg gaaagggtag acgctaagca tgtgtgttag gtcaatgctt
     4081 cggcaaccat gcaaggttcg attccttgcc agtgactttg gcaactgagg gttggaaatg
     4141 ggcgctcaaa gtacacgagc aaggcgaggt cgatagtaat cgatggaatc ggtgtaggtt
     4201 gcttgataga actataactg catctcgttt atgaggtgta gtttttacat attagatcac
     4261 tcatcgagtg gtctttttat tttggaaggg gagtaaaaaa atgaacgaaa accaattaag
     4321 agagttgttt aaaacgaatg aagcaaacaa aacaatggag gcgacattct acgaaactca
     4381 aaaaagctta gcgttaatcg caaaacaagc taagtatttc tacgatcagc ttattctgca
     4441 aggatttaat gacgcacagg ctatggaatt tatgatgcga accttttctg ccagtaacca
     4501 acagaaagag tgatacgtaa tgaggaacta ctggtatgta tcattatcaa ataaatatcc
     4561 gcaaccaaac gcagatgatc caattagagt tgtccagtca gtccagatta aaaagaagta
     4621 ctccatcatt gaaatgacca gagaagctac gccaaaagag attgataagt acaatcttcg
     4681 ttactgcggc catggatatt ttagtgagca gaacatacag acaaatattg agagatattg
     4741 ttaataaaat tgaaaggtgg tggcttgaat gtggtaaatt tgacaccaaa acaaaaagct
     4801 tttgcggatg aatatataaa aaatggtggt aatgctactc aagccgccat taaagcaggt
     4861 tatagcaaac gatcagcaag agtaataggt aaggaaaacc taactaaacc taacataata
     4921 cagtatatta atgaacggct aaatcctatc gaaaagaagc gcaaattaag tgccgaggac
     4981 gctttaaatg aattgataga tatttggcaa ggagaagtac aaataagcgt gagcaagcaa
     5041 atagaccgct tggagaaaaa caaggttatt aaacatatgc aatatgaata tacaccagat
     5101 ttagaaagca aattgaaagc cttggatttg tatttgaagt ataaatcgct gttatcacaa
     5161 acgcaattag aaaaagctca aacagaaata aaattaatgc aagcaaaatt agaacaatta
     5221 cagataaact cagagcgttc taccgaagaa aaacttgatg agttgttaga aaagattagt
     5281 ggtgaattag atggcactag ttgatattta taacccaaag caaatcgacg tgttaaataa
     5341 aaccattaag aatgattggt ttattacttt attacatgga gcaaaacgtt ctggaaaaac
     5401 aaaaataaac aatgatttgt tcttgtttga attgcgacgt gtgcgaaaga ttgccgatga
     5461 agaagacatt aaggaaccaa tgtatatcct agcaggagtt tcaagtgcaa caatccaaaa
     5521 gaacatctta caggaactat acaacatgta cagcatagaa cctaaattcg ataaacatgg
     5581 aaactttaag ctatttggcg ttaaggtcgt acaagcttat acaggaaaca ttggcggtgt
     5641 tggcgcaatt cgtggtatga cagcatatgg cgcttatatc aatgaggcat cgctagctag
     5701 acaagaagta tttgctgaaa tcgtttcacg ttgttcagga acaggagcga gaatactagc
     5761 tgatacaaac cctgacaacc cggaacactg gctaaagaaa gagtatatcg acaattcaag
     5821 caaaaatatt caatcgttcc actttgaatt agatgataat acatttttat ctgaacgata
     5881 tcgtaacaat attaaagaat caacaccaag cggcatgttt tatgatcgtg atatcaaagg
     5941 tttatgggtt tctgcagaag gtgtcgttta tcgtgatttt gatgctagca agcactacat
     6001 ccagtcaaaa gacttaccac ctttgagcaa cttttattgt ggtgttgact ggggatatga
     6061 acactggggt tcaatcgtag ttataggtga aacggatgac ggaacagctt atttaatcga
     6121 agaacatgct actcaatttg aagagattga ttattgggta gatgtggcaa aaggcattca
     6181 agagcgttac ggcttacgag taccttttta ttgtgactct gcgagaccgg agcatgtggc
     6241 taggtttgta agagaaaaga ttaatgctaa aaatgctcat aaagcacggt tatctggagt
     6301 tgaggaagtc gccaagagat ttaaacaaga taaattgttt atctgtcaag atagagtgat
     6361 gaaatttcgg gatgaaattt atcaatacat ttgggacaag aaaaaaggcg agccaataaa
     6421 agaatatgat gatgtgctag actccgttcg atatgcgata tatactcatg agcttcttaa
     6481 gaaaccaaaa gttaatgtca acgaaaagat taaacgtatt aaacgcatgt tttaaggagt
     6541 gtgaaaaatg gataaggtaa acgagtttga atacggagct gatatacatt attctaatga
     6601 cgtgaacaca aattatgtaa agtttagcgt agactcaaat cttcactata gatttagctc
     6661 agcagaagat ttacttaacg atttagatac tttagcagca atgataaaac atcatcatga
     6721 atatcaggta aaaaggctaa gtgtattaga tgattattat aaagctagaa atacaaatat
     6781 catggataac cgtaggcgca gagaaaaaga aaaagcggat caccgatcag cacataactt
     6841 tggaaaagtt ctttgtacgt ttgatgttgg gtacaacaca ggcaatccta taaaagtgca
     6901 aatcgaggac acaaatcaac aaaaagaaat cgaagagttt aatactaata atgacataga
     6961 tgggttaaat gctgaactct ggcttgatat ggataagtat gggagagcct atgagattat
     7021 ctatcgagat tcagatgata cagattatgt tgatttggct aatgtatttg aaacgtttgt
     7081 tgtatatgat actacagtaa aacgagagcc tattttggct gtacggtatc ctaagacaag
     7141 attcaacaag gatgctgata aacagtacat tcaaccaatc gtatacacaa aagaaaaaag
     7201 tatcacttat gatgagacga cactaacagc aattgagtta aagaatcccc aggatgaacc
     7261 gcatgaatat aaagaggtac ctattacaga gtattctcct aatcgttttc ggatgggctt
     7321 gtatgaagat gtactatctt tgattgatct atacgatgca gggcagtctg ataccgccaa
     7381 ttatatgact gatctaaacg atgctcttct agttattagt ggtgatattg aagcagcagg
     7441 actatccaca gaggacgcca tcaagcagaa agaagcgaat atgcttttgc ttgagtctgg
     7501 aactgatgtg aacggtaata aaacaagtgt gactgcagga tatatttaca aacaatatga
     7561 tgtgaacggt gtagaagcat acaaatacag agtacgcaag gatattcacg aaatatccat
     7621 ggttcctgat cttactgatg acaatttttc cggagtgcaa tcgggagaag caatgaaata
     7681 taaattattt ggatttgaac aaatgacggc aacaaagcaa aggctattca aaaaaggcct
     7741 tatgcggcgt tatcgtcttt tatttagcct aaaatcaagt atttctgaaa tggataactc
     7801 cgatttgaaa ggcttacgtg taatatttac gcctaatcta cctaaagcca ttctggaaga
     7861 gttgaaatct ttggttgatg ctggagctga actcagtcaa gagacgatct taggactcgc
     7921 ttcttttgtt ccagatgtac aggcagagtt gaaacgagta aataaagaaa cgcaaaagca
     7981 gattggcatt tttgattcag atggtgaaga agtaattaac aacaaaaaag atgaaacagg
     8041 ggggtgatta aatgaactcc caagaatatt ggatcaaacg ggaaaaggaa tggcaaaagc
     8101 aacaaattaa agatgataaa aagcgcatgg cagaaattaa aagtcgcatg caatacgcac
     8161 aagatgcgat acaaaaagaa atagacgcgc agtgggacag tttctccaat ggccagaaaa
     8221 tcactcgtag cgaagcgatg aagcgtgcta gtgaaatgga tgtcaaagca ttcgctcgca
     8281 aagcaaagaa gtatgtcaaa gagaaagatt tttctcctac agcaaaccaa gaattaaagc
     8341 tatacaatct tacgatgcgt gtaaatagat tagagctctt aaaagctaat atcgggcttg
     8401 aattgatttc actgtttaat gaattggata agtacttttc gaatgaatta acaaaagctg
     8461 gtttagctga attgaagaga caagccggta ttttagaaat gactattgct tcaagtggat
     8521 atgcaaagct gatagaacta gtaataaaca gctccttttt gagtgatgac gtgtctttta
     8581 gtgatcgctt atggatgtat caatctgaat tgaaatcaga attagatagg ttgttagtca
     8641 gaagtataac gatggggaaa aatcccaagc aacttgcatc taaattggca gaatatttaa
     8701 cagctgaagg acgagaaaac actaagttca acactcaacg tttgatggtg actgaaacga
     8761 ctagagttca ggtagggatt caagaacgaa gttatagaga tgcaggcatt acccagtaca
     8821 tctatatagc agaaccaacg gcgtgcaaac tatgtatacc gttaaataat caagtttttg
     8881 atgttgccga tatgcagcca ggaagtaacg ctcctaatat gcatccattt tgtcgatgca
     8941 gtacagcacc ttatatagaa cgaatatcaa gccgttaaca caaattaacg gctttttatt
     9001 gtgccttctt acagcttaca ggcgttaaag agaaagctat tttcggctga ccggcgtaac
     9061 tggtcaaatt tatcgggtag cggcgtaacc gtggaggatt aatcatgaaa aaacgtttat
     9121 ttatgccaat gaacttacaa tttttttctg aaccaggaga tggtggatct ggtgatgagg
     9181 gacaacaagg aaacctacca gctggctcac aagagacacc gcccgaagca aaagaagaaa
     9241 acaatactgg caaaacattt tctcgtgatg aagtagcgaa aatgatcgct gctgagacga
     9301 ataaagcaaa agcagcgtgg gaaaaagaac tagcagcaaa aaaagaagaa gctaaaaagc
     9361 tggcaaaaat gaatgcggaa gaaaaactac agcatgagtt ggagcaaaaa gaagctgaaa
     9421 tcgctgaatt aaagcgtgga caggcactat ctgaaatgac gaaagaagct tctaaaatgc
     9481 tgacagatgc aaatttacca cacgatgatg atttacttgg tctgattgtt tctgatgatg
     9541 cagatgccac aaaacaagct gtagcagtca tcactaactt tgcttctttg attaagagag
     9601 aaaacgcaag acaaacacca ccaaatgaag gtggacaatt tacagcatcg aaaaatacta
     9661 aagaaacagt ggctaaacta gctgctaaaa atcgaattat caaataggag gaaaacttaa
     9721 tgaaaaagaa acaactttta ccaatgaact tgcaaatgtt tgctcaaaca tgggatccag
     9781 ataatgtctt ggtatatgaa acgaaagagg gaaaaattcc tgataaatat aatacgctca
     9841 ttttgagtga agttatggaa aattctaaga tcatgcagtt agcaaaatac gaagaaatga
     9901 ctgacaaaga aaagaaattt gaatactttg cagaaggacc aggcgcatac tgggtgggtg
     9961 aaggtgaaaa aattaaaacg tctaaaccta aatggatgca agctacgatg actgcaaaaa
    10021 aactcggtgt cattcttccg gtttctcgtg aatatttaaa ttataaatta tcagatttct
    10081 ttgaggagat gcagccaaaa attgctgaag ctttctataa aaaatttgat gcagctgcct
    10141 tattaaataa agaaaaccca tttcctcagt cactagacgg atcagttatt agtgcgggga
    10201 atgtggttga aggcggattg acttatgata atatcctagc cttagaagac aagttagcag
    10261 aaaatgaatt cgaacctaat gcgtttattt caaaccgaaa aaatcgtaca gaattacgtt
    10321 ctgcagctca aacagtcggg tcaaatgttg agtttattta tgatcgctct actaatacaa
    10381 ttgacggatt accagtagta gaccttaagt ctttagataa aggaacactt tacgctggag
    10441 actttaatta catgttttat gggatcccat ataatatttc atttaagatt tctgaagaag
    10501 cccaattgtc tactttaact aatgaagatg gaaccccagt taacttgttt gagcaagaac
    10561 tgattgcttt gcgtgcaaca atggatgttg gatttatgat tgtaaaagat gaagcatttg
    10621 ggaagatttc cccaaaagcg taacgcctgc taccggtatt gtgccaaatc aaaagacatg
    10681 gaccggtaaa gtaggcgata ctaaaacatt tactatttca gctgtgcctg cagatgctag
    10741 cgatgcagct gctgttgttg cagctactac agcaacttca agtgatggag ctatcgcaac
    10801 agtgaccaaa aatgaaaatg gtggttttga tggaacgatt gcagcagaag ggtcagcaac
    10861 attcacattt acttctggag aattcactac ttcaatcaat gtgacaggtc aacctgctag
    10921 ttaggaagta aaaatatgat gattgcagat gatattaaaa aacttcttaa aggaacaata
    10981 gatgaaaagc ttgaagttat tgagcgaaga acgaatgagc gtatgaaaac cttgttaaat
    11041 acgcaagaag ttcctaaaga atttgaaaca gttgtatatg aagtatcgtt gaaaagattc
    11101 aatagaattg gtcaagaagg tatgcagtca tattctcaag aaggtttatc tatggctttt
    11161 cctgactcgg atttttcaga gtatcaaaat gagattgatg aatttaagcg taaagatcag
    11221 gaagagttgt acaagccaaa gcgagggagg tttaaatttg tatgagattt acagatgaaa
    11281 ttatatttgt taaacgttca tctgactcta aatatgatcc agatctcggt gagtgggttg
    11341 aaggcaaacc agaaagaaca agaacagagg caaacgtgac agatattggc actgatagaa
    11401 gtgtgactat ttttggtagt gtggaagaag gggcgaaggt cattaggacg cagcctcttt
    11461 tttctatccc tacatttgac tatatcgaga ttgaaggaaa gacttggcaa caaaaaacag
    11521 ctagaaatcc agcatataga aatagtttaa ttgtgcaaga ggtggttctt gatgaaggca
    11581 caacttgaat ataaaggaat cgatcagctg atgcgacatc tgaaaaaagc agcaacgctt
    11641 aatgacgttc aaaaagtcgt gaaaagtaat actgctgaaa tgactgaacg aatgcaaaaa
    11701 ggtgcgccag tggatacagg ttacttacga agatcaataa acatgaatct tttagaagct
    11761 ggtttaactg gtattgtagg accgacagca gattatgcac cttatgtaga atatggcact
    11821 cgatttatgt cggcacagcc ttatgttaga ccagcgttta attaccaaaa agtcaaattt
    11881 atggctgaaa tgaaagcctt ggtgaaatga tgattaagac aagagatcaa tcaatttttg
    11941 atgaactttt taaaatatcc caaaacaaac ttggatataa aacatacgat tacaaaactt
    12001 tagaggatgt tggttatcct tttgtggaat ttgagaacac tcagacaatc catgaagtaa
    12061 ataaaactga cattaaaggg tctgtgattg tggttttatc cgtttgggga ttacagaaga
    12121 aacgaaagca gttgtcagat agggcatctg ctctttttaa tgaagctaga ttgatagaag
    12181 ccacagaagg ctattattgg gctttaaatt atcaagcaag tggaattcaa gtgatggacg
    12241 acacaacaac gaatacaccg ctaaaacggg cggttgtcac acttgaattt agaattagat
    12301 aggaggaaga acatggaagc attaaaaggt attgatgtca ttttgcttta tcgcttattg
    12361 aaaaaagaaa ctcaggaagc cgcttggaaa atggcatttc aaacagaaca cgaaaatggt
    12421 ttatcaagag attcagactc tacagtgaca aaagatggaa acgttcaaag tttaagcccg
    12481 gttgaatatg atttttcggc tacttcaata gttgctaaag gagattctca tgtagatgaa
    12541 atgaaacaag ctttattaaa tggggatatc attgaaattt gggaaattaa taaagcagaa
    12601 cagggaacag atgataatgc aaataagtac aaagctactt attaccaagc atatgtgtct
    12661 gaatttactc catcggctgc tgcagaggat aacgttgaat taagtttatc atttgcagta
    12721 aatggtgttg gtcaagatgg ttatgcaacc ttgacagaag atcaagccga tgttgttcaa
    12781 tatgcattca aagataccgt gaaagcaact tcgacaggag cataagaggg cttagatgct
    12841 ctctttttta ttttaggagg atgaaaaaca ttgaaattaa aaattaaagg taaagaatat
    12901 tcgtttaaat ttggcactaa atttgtacgt gaattagata aagtgatgcc tttcgtcgat
    12961 ggaaatatgg aatttggaat gggactctcc gcaaaagtct taccagagct acgttcttat
    13021 aacgttaaca cgttatcacg agttctggaa atagcaaata gaactgaaga tgaatctatt
    13081 acattagatg aattggatga ttacatcgat gaagttaaag acattgaaaa attgtttgat
    13141 gaagtcctaa aagaattggc ggagtcgaac gcgggaaagt tagcggtccg aaacctgaat
    13201 cagaaattga aagaagcgga aaaacaacaa gtggaataga ttctgcactg gcatacgaac
    13261 aaattcttat caattctttt cgatatttgg gaatgaccaa tatctcagat atcgaaagaa
    13321 tgacgttata tgaatacaac attcgtatga ctgcagccca gttatcttgg cttgacaaag
    13381 aaaagttgat tcacgaatta gcgtgggcaa atcagcaagt ccaagcggag aaaaaagtag
    13441 gcaaaaagac agttcctgta tatcgatcct ttgaagaatt cttcaattat caaaaaatcg
    13501 aagattcaat catgggagtt tccgaacttt caaaacaaga taaaaaattc caaagcttac
    13561 taactaaagc taactcttga ggaaaggagg agaatcatgg aacaattttc tgttgaagcc
    13621 ttattaaaag ccacagatag tggatttgta aagactttta aagatgcaca agatgctgtt
    13681 aaaacttttg aaaagaattc aaatagtatg acaaccgctg ttggtaaagt gatgcaaggt
    13741 actggtgccg caatgacaaa gtatattacc actcctctta taggagtagg cgtagcagct
    13801 gctaaagttg gtggcgactt cgaagcacaa atgagtcgtg taaaagctat atcaggagca
    13861 accggcgaca cattcgaaca gatgaaacag caagcgattg atctaggagc aaaaactgct
    13921 tttagcgcaa aagaatcagc tgctggaatg gaaaacttag cttctgctgg atttagcgca
    13981 caagaaatca tgaaagcaat gccgggtctt ttagacttag cagctgtatc tggaggggat
    14041 gtggctctag cttctgaaaa tactgctact gctttgagag gatttggttt agaagcaagt
    14101 gaagcaggac atgtcgctga tgtatttgct cgtgctgctg cggataccaa tgctgaagtt
    14161 ggagacatgg gagaagcatt gaagtatgtt gctcctgtag ctaattcaat ggggatttct
    14221 ttggaagaaa ctgcagcagc tattggtatt atgagtgacg caggcattaa gggttctcaa
    14281 gcaggtacaa cgttgcgagg agcattgtct aggttagcaa ggccaacaaa ggctatgcaa
    14341 gatacaatgg ataatttagg tgtttcgttt tatgatgctg acggtaaaat gaaaccttta
    14401 aaaactcaag tagaattact taaaaaagct tttgaaggcc tgacgcctga acaacaacaa
    14461 aatgctttag taacactata tgggcaagaa tcattatcag ggatgatggc tttgattgat
    14521 aaaggacctg attcattggg caaattaaca aaatctctga aagattctga tggtgcagct
    14581 gacgatatgg ctcggaccat gcaagataat atgaattctt ccatcgagca aatgtttgga
    14641 gcttttgagt cagcagctat tgtaattcaa aagattctag caccatccat caaaaaagta
    14701 gcagatgcca tatccggctt agtagaaaaa tttgtaagtg ctccagaatc aactcaaaaa
    14761 ttagtagtgg ccataggagc aattgtcgct gctataggac cgttaatttt tatgattggt
    14821 tcagtaatta tatggatcaa tagggtgaaa gtagctttta aagctttaag tgaaagttca
    14881 aaattgttta gtggattaag taaagcaatg ggtcttctta caaatccggt ttttctggtt
    14941 atagctgcgg tagcactact cgttgtaggt ttcatctatc tttggaatac gagtgaagat
    15001 tttagaaact tttggattgg cttatgggag ggaatcaagt ctgctgtaag ctcggcagta
    15061 gaatggattc agaatgcatg gaaatctaca ggagaatggt ttaacaattt atggaagtcc
    15121 attaaagaag gcgcagacaa tgtttggact acagttcaag aagcccctgg gaaagcggca
    15181 gattggatta aaaacaaatg gactggaaca aaagagttct tttcaaattt atggtcaagt
    15241 attgcaaact ctgcttcaga gatttggaat agtttaaaag aaggtgtcat atcagttatt
    15301 gatgatttag tttcaagtgc tggtgaaaaa tgggaagggt ttaaaaatac tatatctact
    15361 gcatggaaaa caattacaag taaaatcaaa tctggttttg attttatact aaaatatatt
    15421 ggtccatttg taagtagctt ttcagatgtg ttctctaata tagtgaaagc aataacaagt
    15481 atatttgctg aggttaaaaa cataatagta aatgcttggg aaatcattaa gtctttaata
    15541 gctgcgccac tactgtttat tatagattta attactggtg acttcgaaca aatgaaagag
    15601 gatttagatc taatctggaa cacacttgtc caatcagtgg taaatatttg gacatctgta
    15661 aaaaatatat ttacggaata tatcggtgca atagtaaata gtgccgttag tttatggact
    15721 ggattcatac aaagtatttc taatatttgg aatgaagtag tttatcaagc gactatgatt
    15781 tggattgatt tgaaactatt ttttactaat ttatggattg atattaaata cagtgcaatt
    15841 caaatgtgga taaatctaaa attctccata attcaaactt ggattgatac aaaatatggt
    15901 gcaattgaac tttggaataa tctaaaacaa tggtttttcc aaacggttaa taatatcgtg
    15961 caaactctta taaaaagttg gaacagctta aagcaaggaa cgatagattt attcaacaat
    16021 acagttcaag gtgctaaaga catttggact tcattcaaat cttggattgg tgatttaatt
    16081 actggaacca aagataacat cattcaggga tgggaaaacc taaaacaagg tactatagat
    16141 actttcaaca atttagtaaa tggtgctcaa gaggcatggg ataatttagt aaatgctgtt
    16201 agtgacacgg ttgatagagt aactggctgg tttgataact tgaaaaatat cgatttacta
    16261 gcagccggaa aagctatcat ggatagtttt ctagaagggt tacaaaatgc atggaaatct
    16321 gtgcaagatt ttgttggagg tattggtgat tggattcgtg aacacaaagg acctatccaa
    16381 tacgatagaa agctattgat tccagctggt caggctatta tgaacggtct gaataaaggt
    16441 ctgacaggag gattcaatga cgtacagaat actgttggaa gtatggcaga ctttatcgcg
    16501 gaacttttca atgcaaattc tgatgtagat atagctgcaa atttgaaaaa tgcaaataaa
    16561 aacattggtg cacaagttga acataaaata aatatgggtg gctctactaa accagctgta
    16621 tttaaaatca atcttggaag acaatcgttt agattgttta tggacgatat ttcacaagct
    16681 atgggcgaag gtgcagatat taatctggaa ttttaggagg gaatattttg gatcaacgag
    16741 aaaataaaat gtactcattc aaagatacaa ccattaatct cactagttct aaacgattcc
    16801 ttccgacgtc tgccatgatg tacgatggaa tgtatttaga agatttgatt gatggttatc
    16861 aaacacttac ggtggaaggt agagaaatgc tttctgtaga agttgaacag caagagatac
    16921 aaattggttc aatcattaca aatcagaaaa taccttcaag aacactaaaa ataacatata
    16981 agctggaaga tagagatcca gaaaaactac agtttaaatt caaagaactg ttgaattatt
    17041 tataccggaa tgaagacgtg gaaattaggt ttcatgatga attagattat tattactacg
    17101 gtcgctatac atcaactgat actgttccag gagactccaa ctcgattatt tcgagtttta
    17161 atgtattctg tgcggatcca ctaaagtata cgaaagagtg tgttagtgat ggctatattg
    17221 gaaatccgat acagtttcct ataacaccaa gaaaaattga agttacttta tccatgaata
    17281 attcaatcaa aattacaaac ggagaacaaa atatcacgat aactgacgcg gcaataaaaa
    17341 caggagacgt gttggttttt gatttttccg atgagcaggt aactgtaaac ggagaagatt
    17401 gtacttctat gattgattta gaaagtgatt ttgagaactt ttatcttaag caaggtcaga
    17461 agataactag caataatggg aagcttaaaa tattctatag gggggcgaca atttgagtga
    17521 gacagtttat ttctttgatc acttgcaaaa acttattaaa agaaaaaata caagaagttt
    17581 gattgaagtc tcccaagaaa aagaaattag ttctgataag agtgatctaa tgaaagatac
    17641 tctttacgtt acgacaaaat atgataaaga aatagaggat gcaagatata tggcgattcg
    17701 tgaaaacgag tcgtcttttt cgttgtatcg aattactaaa gttagcgacc catttgaaac
    17761 attagagttt acagggttag gatttgcgac aaatgaatta gatgcttaca tcatcaaaga
    17821 tattaggccg agtgggcagc ccttaaaaaa tgttcttgat cgattgattg aatttactga
    17881 aggaaattgg cgcgttggtc acgtagaagc aatgttacca acagtaactg caacttttta
    17941 ctatgtctct gtaaaagaag cgttgaaaga attgcaaacc ttaggtatgg aatttgtctt
    18001 taggtgttct ttgaattctg atggaataaa ggataaatgg atcgaagtat atgaacaaat
    18061 tggcgaagaa tcgaatacac gtttcgtata tggtagtaaa gcattaacag ttgtaagaga
    18121 gatagataga agctcaatct caacttcaat gataggtcgt gggcgaggcg aagaggttgg
    18181 tgacggttac ggtagaagaa ttgaattcac tgatgttgaa tggaaaaagt cgaatggtga
    18241 tcctttagat aagcctaaag gccaaaatcg gcttgaagat ccggaatcaa ctcaaaagta
    18301 tgggatacca caaaaagatg gatcaatgag aaaacgagaa accgtagtag tgtttgatga
    18361 tatagatgat ccaacagatt tacttaaaaa tacttattca accttaatcg attctgctag
    18421 accgttagta caattcaaag ctgaagtcac tggaggagat gtgataggaa atacagtgac
    18481 tattcacaga tacgataaag gttatcacta taaaactcgt atttataaaa ctacattcaa
    18541 tcggcttacc ggtcaaacga atatcgaact aggggataat ttaacacaag atgttagaaa
    18601 acaaacggct tctattgtca ataatattaa tagtttagaa tctagcaaaa tgacatttta
    18661 cgaatcgaca gagattggaa aatatcaaga tgacattatg cgaggtgcag gagataatgg
    18721 cggttctatt tattgggtaa atggaattga agctggtgtt agtgatagta gagaaatcta
    18781 tgaaactgtt tatatggatg gacctaacat tcctagatca cgctttttta tggtccaaaa
    18841 taactcaggg atatctttca aacaatgtaa aaaaggtgag tggcaaacaa ttcaagatgt
    18901 acacaatggt gatagcacga ccgcttggac gttggatgga actttcaatg ctaattttat
    18961 tcgcgcaggc attctgtctg gtatcctcgt gcaaggggta gctttaaaaa catttgacga
    19021 taaagatttc caattagtgg cagagggggg agaactttct tttgaaaaac aagtcaagtc
    19081 tactggacta gatgatgtac atggagaacg cttgggctca attgtatcta cttatggttc
    19141 taaagggatt aacggctttg ctgtctggaa agagccaaac tatatttttt ccattaatgc
    19201 tggggacggt ggcgatcgag ggaatcctat ttttcaaatt ccagcagatg ttactgctga
    19261 taagcgcaaa tataatcttt atggtgacgg caatttttca gaaggaaata taaccataga
    19321 tggacggcta gatgtaaaag aactctatgt taacggtaca aaaattgaca ctaatggagg
    19381 aggcaattcc ggagggaacg ataacggttg gaacggacaa tacccaccag aagtaactac
    19441 tgatcgggat aaacgatatt ggcaaatttg ggcaacggca ataggtgccg gttttacaca
    19501 acaagctgct gcagccttac ttggaaatgc acaaggagaa tcagatgcta atccaaccgc
    19561 tgatgagggc aatggcgcac cagggttcgg ttatggtgta tggcaatgga ccgattcttc
    19621 tggcgcaact agcggacgtg tctacatgat caatttaatg acaaaggctg gcatcagtga
    19681 tgatccagac acaatcacgg cacagtttaa attgttgatg tggcatgcac caaatggtca
    19741 atggatcgca actagcgctt atccttacac atggacacaa ttcatgaatc tgaccgatat
    19801 caacacagca gcacaagcat tcgtggctaa ctttgaacgt ccacgtgatc cacatccaga
    19861 acggacggca tggtcacaag aatggtatga caagttcaaa gatttggaaa ttcctgtatc
    19921 aaaaggatat atgaagccga ttgcggatcc aatcacagtg acgagcgaat ttggctggcg
    19981 cacttctcca atcacaggag cacaagaatt tcataacggt attgaccttg taaatggaaa
    20041 tcctaataca cctatttttg cttcagcgga tggcgaagtg attgttgcag gtgatgcaaa
    20101 ttactttgac tggtatggaa attggacagt gattaaacac gctgatggaa tgtatacagg
    20161 atacgcgcat caaagccgag tagacgtctc aaaaggtcag aaggtaactg ctggtcagca
    20221 aattggactg atggggacaa caggaccatc cactggagaa catcttcatt ttcaatttat
    20281 ggatgagttt tatccatctt cttcaggtca tttccacaat gcaagagact acatcgattt
    20341 ctaaaggagg gatagtcatg gcagaaacgc agcataaaat ggtcctatcc accaccgaac
    20401 caaacaacgg aataaatttg gttcgaattc ggcaagggga tgttttaacg caaaagttcg
    20461 ttgttgaagt ggtggaacat ggcaaactaa aaacattcga gggcctagtg ccgtttttta
    20521 ttaatacaac aaaatttggc gaaaaccaac ctgttgaaca aaaagtacaa gaatacagtc
    20581 cagcgcaagc aaggcttgtt tacaccttaa gtgagcctga ctggcaatgg ggtggtgaaa
    20641 acaccgcaca tttcagtttc cgatcactta atggtgatgg aacttggagt gaacaattta
    20701 gcacacagga ttttacctat cgagtcattt ctggaatatc tagaagccag ttacgtgact
    20761 ctggctatgt gtggacattt gaggatttgc taagaaaatt caaagattac atggatcagg
    20821 gcaaaaatga ctgggagcag tggttagaag ataatcgtga aatactggaa aatatcgatc
    20881 caggtggtat gatcattaac attctgaatg aagctaaagg cgactacgaa tcattagctg
    20941 atcgtttaaa ccaaaaatac caagtgccag tcggcagctc acaaattaga gaaacaacac
    21001 gcttttttga ttacgacacg atgaaatacg ttgacctagt gccgcgcaat ttgaatacgg
    21061 ttgtcaacag tgttaataac agcaaattta acttttcttt cattacagac attcacgcag
    21121 ataatcacaa cttgcgtata gatggcgtcg gttacaaaga tgcttcttat ttaagacatt
    21181 ggcgcgcaat ccctcaattt caaaaattag ggaacaaaac agatgtgatg atttacggcg
    21241 gagacaatat cgacggcgga cttggttcac tcggcagcga tataggcatt attgatgaat
    21301 ggagcgcgcg acattccatg ttaggcacgc tcaaacgctt cactaacgca gcggtagcag
    21361 gacaagaaaa accggttatt atctgcaaag ggaatcacga cgcttgtttc gaccccgcgt
    21421 ggcgcaagcg aaagggaatg ttatgcaacg ctgacttcga agagtattgg aacggtttgt
    21481 acggtggcgt gttgttccca gataaaaacg cagcaattta ccgtttcgat acttgtgatt
    21541 tttatgaagg cggcacaggc gacaagtacg tggacggtta cagcgataca gcgccgggag
    21601 ctttcagtgc caaacaaatt aacgctttcg gagaatggtt agtgaacgtt ccgagaaact
    21661 atcatgtggc gttagtagga catacgcctt taggtctcag caagtttccc gttcgcaatg
    21721 aaaacatgat tagcacgttg atagaagggt ttaaatctgg tagtccggta actatcgatt
    21781 ggtctaaatt aggacaaccg aatgacggtt cgttcggcgg attaaagacc ttcgcaatga
    21841 atacaaaagg cgccggcgtt gtagtaggtt atttctgcgg gcattggcac gaacaagtcg
    21901 aaggggcgtt tggaacagta aaaatgattc tttgcgacgt cggcttctct catacagcta
    21961 gccaagttga tacaccggat gaattagcgt tttataaaat agaagttgac acagcaacaa
    22021 gaaaagtgac aagcaaaggc gtagggcgcg cgagagactt cacttataac tattaaggcg
    22081 gtgaacaatt aaatgttaga ttttcaaagc aaaccaaata tttttgaaga aatgagttat
    22141 gaagaggctg tgaaatggtt attgcgtcaa gcggctatcc attacgacgg ctcggatcac
    22201 gacgcgcacg tcctagctac tgaaagcaac gcgggctttg ctacaccgga aacagttatg
    22261 caagcgcgtg ggcgttggtt acgcgattat aagctaccac aaaaatatcc gaacatttta
    22321 gacattccgc ccggcaaata cgcaaccaaa gccggatggg gcgcagacaa ccctgacggg
    22381 attgaagatg acagttttgt tgaaatgatg gtattcgcgg atcacgattc gagaaaatta
    22441 atcgtcgctt ttgctcgtta tagcggcgaa atttacatca aaatgacaca taacagcgaa
    22501 ccggtagagg gttataactc gttaggctgg cggcgcgttt acactacttc tgttcttttt
    22561 gaaggcgaat taagaaaagg acaatcagtc aatctgccag atgatacttt ccgttaccaa
    22621 acgcttcgta tccactacac agacggtgac ggagactttg tagaagaagt gaaacgtcaa
    22681 agatacgcgc gaattacaaa agcgaattta tggaatggag acgcgggagt gacgttcatc
    22741 gaatttgagc tgacaatcga agcgcgaaag ataacgatgt caaacggcag agctttagat
    22801 atttcatccg gcaatgtttc caatcccgca atgagcaaca acgtgaaaat aactaagatt
    22861 gaaggtgtga aataatggcg catgtcatca aaaaaggctc tatcaaagta cctacacagc
    22921 cgaaagacta cgatttgcaa gcaacggggc ttgtatttaa atcatacgat aatcaaatag
    22981 cgttagagtt caacgtcgaa caacagaacg gcacaccggc ggacttgcta ggagctaact
    23041 tgcgcttgtt gatgtttatc tatgatgaag tagatggaat gatcacgaaa gagccaatcc
    23101 cttttatcac gaaaaacctc atcactgaaa gcttcttgaa tggacaggtc gtatatatct
    23161 tgccagaagc gatgaaagct tataacggta tggtggaagc ttatgtttac atcgagtatc
    23221 cagacggatc aacaagtgat aacttaggct tcaccttccg tatgaagcgt tcagcaatcg
    23281 acggactagc gcaagataaa gcagactact ttattgcaga ctttcaacaa ttacttgatg
    23341 gagtcaaaca agaagcaaca gatgctgtta acgcagcatt aacaaatgtg gattctacga
    23401 ttgaaaaggc aaaccaacaa ataaatgaat ttgtagaggg agccacacaa gcaattgatc
    23461 aaactgttga cgaggtaaca gagcaactac aagctactca aactaagatt gataccgttt
    23521 ctcaaaacgt tacatcggca caaaacaatc ttaaagcagt tgaagacaag atgaatcaaa
    23581 ccaatcagca aatcggcgac ctcggcaagc tgaaaaagat gtacagtaac agcatcgact
    23641 tcgggaatta tgattatagt gggaatccga atttaatgtc caaactaaaa tcgagcgatt
    23701 ttaacgttgg ttaccacggg tcactaactt cggataacga aaagctacat tttacttctg
    23761 atggtacagg aagcattatt atgtttacgc gtattaatac acctcagctt gctagtggga
    23821 aaacctatac tctgagtgcg aaagttcgat ttgatgaagg aactacagga gctattgata
    23881 aattacgttt ggtgtatcgt acatcaccag gagaaaagat attattggaa gcaaatagta
    23941 caaatattac aacagatgat gtagggaaag aaataacaat caaaggtaca gctaacgtta
    24001 attatcaaat cacaaattta gatcgatttt atatgagtat tagctttgtt gacagggata
    24061 aaataaatgg cggatttaag ttgtacgaca tcaaaatcga agaaggctca acagccaccc
    24121 catatcagcc aaacttactt gatgaccctt actggctagg taaagcgcct ttgggtgaga
    24181 atattgctaa taagtctgtt acgtttccaa tcaaatctag cgcctacagc ctataccaag
    24241 ctaacatgga agaagaattt gttttaggtc aaacctatac aattaccatg aaggcaacca
    24301 aaccacctat ccaaacgttc attgtttaca acgaggatag tggagattat agatatggta
    24361 acttagagcc agtagaaggg ttagttgata catggggtct gacttttaca ccgcagaagg
    24421 ttggagttaa ctaccccaaa cggttaacta ttatccagta tccccaatca acaacaggtg
    24481 catgtcaaat tgactggctc aagatcgaaa aaggcgacac acgaaccccg aatattagtc
    24541 agtttaaata ctttggtgaa ggcttgaaag acagtaacaa tcccaatgat tacagttggg
    24601 atgtcacacc tgaatatact gaaaaaggct tgaatgatgc tgttaatgtg tatgatcctc
    24661 agagagttga aggtttgaaa aactttgccg atggtattca aatagcagga gataaagtga
    24721 tcagtgaaaa tgattgcact gtttatacat taactaaaga caacagtcaa tcgtttatcg
    24781 atgggtatgc aacatttatt aaacacggaa aagaagttat tgtaaatggt acagtaaagt
    24841 tcaaaaaagc ttatgctttt ggtgtaccac ttgatgatga agtcccagat gaatttgtcg
    24901 caaaaattgt tcatggcatg cttacaggtc cgtcaggaac aagtagtgta tcaaaagcga
    24961 tgtacgtgcg aaaagactta ggaacaatta ttacgaatag cgaatttgct gcaaatgaat
    25021 ggtttacatt ccatggtaat tattgggtag gggaggaata aaaatgaaaa atatttggaa
    25081 atacggacga acaggtggag agtatgctgg acaagtgctt gatgatatgg ttatgactgt
    25141 tccatttacc gatgttccac cactcgaagg aattcgtgct gatggggaac cactaacgat
    25201 tgctgatcag atgtttgatc ctaaactgaa ccaatggatt gttttagtga atgtactaga
    25261 tcacaacgat ttaaacaatc tcaaagcgat gtatgagtcg ttagaaaatg agaacggcga
    25321 tttaaaacag ctcaacgcca aactcatgct aagcgatgta gcgattaaac aggaaaatac
    25381 tgcattgaaa gaaaaagcgg atggtttagc acaaatcaat tcaaaaacga tgcttgcttc
    25441 gttccaaaat agcaaagaca ttgcagaaat taaagagcaa ctaaatccag cttcaaaggg
    25501 aggtgagtag tatgtttagt tttagcgatg tgaaaatgat gtatgattgg ggctgtttta
    25561 ctgacgatca agttcgacta ttcgttccac tatgcattac agacgaagaa gcagaaaaaa
    25621 tcattaataa agataagagc gcatcttaag tgatgcgttt ttatttaagg taaaggagtt
    25681 gtcacatgat taatttagga gaatggggaa caatcgcagg atcaatcact gcgattgttt
    25741 ctttgatttt attagtaata agaccagtca ctgcatcttt ctcgaagatt actgaaactc
    25801 tttcaaaagt aagtcacaat ttagatttgc tgactaaaga tttagaatcg agcaaatcag
    25861 atcgattgat gattcatgaa gaactaaaga aacacgatga aagattagat acacatacag
    25921 aaaaattggt agaacacaca caacaaatca aaactttatt tagagaaaga tctcggtaaa
    25981 aaagaaagga gttaagaaga aatgatttta cccgataagt attatcaagt cattaaatgg
    26041 acagttttaa cagtattgcc agctgcatct gtattagttg caacactagg caaagcgtat
    26101 ggatggaatg gaacagatat gacagtactc actatcaatg cagtagcaac atttttaggc
    26161 gttatcactg gcgtgtcggc ttataatttg aaaaaatagg aggaaacaaa tgaaaaagaa
    26221 aattactatt actgcgatga gcctattaac ggctcttttt ttattgccaa ttaatgggtt
    26281 tgcctatacg attaacaatg aatttaattt aggcccaaac gaaggtagct cacaagtagc
    26341 aaataatcag tacattttac tgcatgaaac ggctaatgaa acagcaacag gacgcaatga
    26401 agcgcagtat atgcaacgtt catggactag cgcttatact gcttatattg tgggagacgg
    26461 cggaattgtt tatcaagtcg gtcaacctgg ttatgtacag tacggtgctg gttcgtatgc
    26521 taatgcaaat agtcctgtgc agattgagtt acaacacaca catgataaag caacgtttga
    26581 gaaaaactac aaggcatacg ttgaattagc tagagattca gcaatgaaat atggtattcc
    26641 acttacacta gacacaccgt ataatcaacc agggatcaaa tcgcatttat gggtaacaca
    26701 aaatatttgg ggcgatcata cagatcctta cggttatctt tctgaaatgg gcgtaagtaa
    26761 agaaaaatta gcctatgatt tggctcatgg atttaccgat gaaaatccga caacttcaga
    26821 tgataaacca gtcattgatc caactcgagc aggtgctgca aatcctaccc tgacagatgg
    26881 aacaaattac gcccacattg atcagttcgg agaaatcgaa aacgcaaact tacatgtggc
    26941 tggttggcac atcgctaact ataaatacga gtatatcttc attatggatt acaatactgg
    27001 gaaagaatta gctcgagtaa aagctgatgg aatatataga ccagatgtaa atcaagctta
    27061 taatacttta ggaaatgttg gctatcatgt atcttttaac atgcgcaact tccctaataa
    27121 gaaagtctat gtaatgatgc gggcaacgaa tgatccagaa gggaacacta aaggcggagc
    27181 acaagatttt catgataaac gctggtattt aaatattccg caacgataaa aatagcccct
    27241 cgtttttgag gggaagtaca taatgcaaat ttgtccataa cttattgatt atcttgtaaa
    27301 aatgcggtaa tttaatagtt agtgagaaga ggtgcttaat tatagttaaa aaagaggaaa
    27361 tagaagcagc atgtaaccaa gcaaatgtta ggtttattgg agaagcttta tctggatatc
    27421 ctaagtataa atacttacac aactggttac aaagtaaaag tttttatctt aataaagaaa
    27481 gatgcatgcc taataaaaat tatagggttt ataaaagagg aactattgta tatgttgatt
    27541 ttggggtgaa cgtgggttat gagttatctg gtaatcattt tgctattgtt ttaaataata
    27601 aagataattc gaaaaatggt gttgtatgtg tagtaccaat ctcttcaaaa aagaaaagta
    27661 attatgtatc tgtaggaaaa atattagaag ttgctagtat taaacaattt ataagccaag
    27721 ctgataaatt aaaagagaaa cttaggataa ttattttact ttcattaaat agaggcatca
    27781 ttgatgaaag cgatttgaat agttttatta aagatattga agctaaaggt gaaaagcttt
    27841 cagtggaaga agtagaaaaa cgagctgtaa aacataattt ggtttgcgag acaagggaac
    27901 aagtaattaa agaaataaaa tcattatctg aagatatggt aaaatatcag aaggtgttta
    27961 attgctacaa gaaatataca caagaatcct atgtaatgcc acttaatatc caaacgatta
    28021 gtaaaaatag aattagaaga attaacaagt ttgatccttc tggaaatatg aaggcacctg
    28081 gaaatgtcct caatgaagta gatgaaagtt taaaaaaata ttttacaaag taaacgatat
    28141 ttttgttgac atttttctgt tcgttagtta ccatgtagtt atagaaggac gtaagcgcct
    28201 atttttaatg tacacatcgg gacgtatgcg cccacataga aacatagttg agagacatct
    28261 atatggtgtc tcttttttta ttaatatgca aaaaagtcta gttttttcaa taatatttat
    28321 gtaataataa attagccacc acaacaaaga atgaaaccca ttattatcta gtctatgtcc
    28381 attctttttg tttgcagtag ttgtgatggc tttccgtact cttagctcag ttggttagag
    28441 cagacggctc ataaccgtcc ggtcgtaggc tcgagtccta cagggtacat actctaagtg
    28501 atttaaattg cgaataaaat ataaaaatga ctcccctttt gactccccca agcagtatat
    28561 ggatgtctct aaaagttgtt tttttagata ataaaaagct gataataagc gaaaaacact
    28621 taaaatcagc tttaaaccct attctcgaaa tccggcgaac cggctaatac cggcgcgcag
    28681 gttcaaatcc tgtaccttcc ttatatcaac gattagaggt tgtgaagaag ctgtcctgca
    28741 tcaagtaata agaacggcca aacaaaaata gcttttccta ttttttcgtt tgattgggct
    28801 tattaccgca gatgcaagct tttgaacacc gtttgttcgg aataaggggc tgtgacaaga
    28861 cttttgtcac agccccttat tgttgtactt ttaacctaca atattttttg attccccctg
    28921 agtactattt tttataaatg ctagtaaatc aatcttcttt ggcctttttt tgataaaaaa
    28981 aatactagat gtaagataaa agtgtaaaaa cgatttgttt taggagggga aacgatgtgt
    29041 accgcaatca cttatgcaac gaaagaccat tattttggaa ggaattttga ttatgagatg
    29101 tcttataatg aagtggtcac tattactcca agaaattatc gtttcgattt tagaaaggta
    29161 aaaaatttag ataaacatta tgcaatgata ggaatagcag ctggggtatc caactatcca
    29221 ctctattatg aggctacaaa tgaaaaaggg ttgagtatgg caggactgaa ttttcctggc
    29281 aatgctgatt ataaagaatt acaagaagga aaagataacg ttgcaccatt tgagtttatt
    29341 ccatggatac tagggcaatg ctcaaccata gacgaagcta aagaattatt ggctactatc
    29401 aatctagtca atatcgattt tagtgaaaaa ctacccttgt cacctttaca ctggttatta
    29461 gctgataaag aaaaatcgat agtaattgaa agtatgaaag atggacttca tttatatgat
    29521 aatcctgtcg gtgtgttgac aaataatccg ccatttgatt atcaattatt taatctgaac
    29581 aattatcgct cgctatcaaa tgga
//
LOCUS       DAIGSZ010000036        28603 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.036, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000036 DAIGSZ010000000
VERSION     DAIGSZ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.036"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            137..1177
                     /locus_tag="NOB31_001637"
     CDS             137..1177
                     /locus_tag="NOB31_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI0973846.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
     gene            2024..2356
                     /locus_tag="NOB31_001638"
     CDS             2024..2356
                     /locus_tag="NOB31_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HCI0973847.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            2975..3316
                     /locus_tag="NOB31_001639"
     CDS             2975..3316
                     /locus_tag="NOB31_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HCI0973848.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYYQKLTDNPIGFGLLPEDDEGNEWFKMTLTNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            3430..3669
                     /locus_tag="NOB31_001640"
     CDS             3430..3669
                     /locus_tag="NOB31_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973849.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            3781..3975
                     /locus_tag="NOB31_001641"
     CDS             3781..3975
                     /locus_tag="NOB31_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973850.1"
                     /translation="MEEKLLKTMKQKHLKRLSVMQYINDMQITGKEKACLLGSMKNFE
                     QLRRTYVKTSSNCQLLLEVS"
     gene            4061..4732
                     /locus_tag="NOB31_001642"
     CDS             4061..4732
                     /locus_tag="NOB31_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HCI0973851.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQQEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            4785..6761
                     /locus_tag="NOB31_001643"
     CDS             4785..6761
                     /locus_tag="NOB31_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI0973852.1"
                     /translation="MAINRYVKKAGMLIGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            6776..7528
                     /locus_tag="NOB31_001644"
     CDS             6776..7528
                     /locus_tag="NOB31_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0973853.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLESNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            7544..8299
                     /locus_tag="NOB31_001645"
     CDS             7544..8299
                     /locus_tag="NOB31_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973854.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKNRVKKLSSDQLKLVSNEETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            8312..8572
                     /locus_tag="NOB31_001646"
     CDS             8312..8572
                     /locus_tag="NOB31_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973855.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            8569..10659
                     /locus_tag="NOB31_001647"
     CDS             8569..10659
                     /locus_tag="NOB31_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI0973856.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            10686..11150
                     /locus_tag="NOB31_001648"
     CDS             10686..11150
                     /locus_tag="NOB31_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973857.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            11147..11389
                     /locus_tag="NOB31_001649"
     CDS             11147..11389
                     /locus_tag="NOB31_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HCI0973858.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            11407..11709
                     /locus_tag="NOB31_001650"
     CDS             11407..11709
                     /locus_tag="NOB31_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973859.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            11779..13842
                     /locus_tag="NOB31_001651"
     CDS             11779..13842
                     /locus_tag="NOB31_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973860.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKYEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            13842..16454
                     /locus_tag="NOB31_001652"
     CDS             13842..16454
                     /locus_tag="NOB31_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HCI0973861.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            16451..18982
                     /locus_tag="NOB31_001653"
     CDS             16451..18982
                     /locus_tag="NOB31_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973862.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKEND
                     QSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            19032..19364
                     /locus_tag="NOB31_001654"
     CDS             19032..19364
                     /locus_tag="NOB31_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973863.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            19365..19958
                     /locus_tag="NOB31_001655"
     CDS             19365..19958
                     /locus_tag="NOB31_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973864.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            20121..22145
                     /locus_tag="NOB31_001656"
     CDS             20121..22145
                     /locus_tag="NOB31_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HCI0973865.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            22145..23344
                     /locus_tag="NOB31_001657"
     CDS             22145..23344
                     /locus_tag="NOB31_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCI0973866.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            23360..24004
                     /locus_tag="NOB31_001658"
     CDS             23360..24004
                     /locus_tag="NOB31_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973867.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            24015..24821
                     /locus_tag="NOB31_001659"
     CDS             24015..24821
                     /locus_tag="NOB31_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973868.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            24843..25073
                     /locus_tag="NOB31_001660"
     CDS             24843..25073
                     /locus_tag="NOB31_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973869.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            25587..25895
                     /locus_tag="NOB31_001661"
     CDS             25587..25895
                     /locus_tag="NOB31_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973870.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            25897..26319
                     /locus_tag="NOB31_001662"
     CDS             25897..26319
                     /locus_tag="NOB31_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973871.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            26339..27928
                     /locus_tag="NOB31_001663"
     CDS             26339..27928
                     /locus_tag="NOB31_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973872.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            27940..28275
                     /locus_tag="NOB31_001664"
     CDS             27940..28275
                     /locus_tag="NOB31_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973873.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            28416..>28603
                     /locus_tag="NOB31_001665"
     CDS             28416..>28603
                     /locus_tag="NOB31_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973874.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        10671 a         4376 c         5810 g         7746 t
ORIGIN      
        1 ttttatttct gattttaggt agtatttaat taaaaaacag ttttaatgcg tttgcatttt
       61 ttatttatct ttgctatttt cgaaaagagt aggtaatttt acataaataa aacaacgtga
      121 aagtagagga tctacaatga ctgattttaa tttttttaag gcggatagag tttacaacga
      181 attattttat caatttccaa aagtctttat tgtttctgac gaatacaaaa aaatgaaaga
      241 ttcaactaag attgcctata tgcttttaaa agcaagatta gagatcgcaa tcagcaaacg
      301 gcaaatcgat gaagaaggta atgtttattt tacttatacg acaaatgaac tatgtagcgt
      361 attaaactgc caaaaacaaa aagcgatagc aatcaaaaaa gagttggaat cctttggttt
      421 attattacaa aagcagatgg gatttaacaa acagttaggg aaaaataatc ctaatagact
      481 atatctagca gaattaaaag tctcagaaaa tgatatctac ttactcgaaa aatttgatag
      541 agagaatagg gaaaacgttg ataaatcaga gggtatgaaa atcataccca ccctcgacga
      601 aaaatcagac gctgaatccc ttggggctca agagggtatg aaaatcatac cgtgccaaaa
      661 cgttgataaa tcagagggta tgaaaatcat accagaactt aataataata tattagacac
      721 taatagacac aatatagaca ctgaaaaaga ccgcctacaa gatcaattgt tgttagacaa
      781 ttttgagaca attatgacaa acgacagcat tgctacgttt atccctgaac gagtattaaa
      841 tttaataaaa acattttctt caagttacag tgaagctcaa aaaactgtcc agactattca
      901 taatgcaaag aaaaaagccg aaacagaaag tggtatttca ataatttttg aagaactcga
      961 tagttattat gtcaatgcag aacaagaatt atacacgaca ctgttaaaag cctatcaaaa
     1021 attaaaaacc gaaaaagttg aaaatatcca gaacctgatt tttgtctatg taaaaaattg
     1081 gtttatcgaa aaaccaatag ctgctaaagt atcaagtgaa aaacgtttga attctgaaag
     1141 cttcccaaaa actattacga aagactggtt agagtgaaat ttcactgaca aattgattgt
     1201 tgcttcatgg agtagcatta aaattaaaaa ttttttatta ttctaattat attacaaatg
     1261 ttacaaagaa atagctattt taatagaatt tatgagttaa aatattatga taaaaatcac
     1321 aaacgtagct ttttacgtca taagtgttaa tagttaataa ttaatttcca acacaaaaaa
     1381 gagaacaaac gtttgcatgt tgctgttttt tagttataat aatacgcgaa gagaggtaat
     1441 ttcatttttt aaaaaagcta aaaaccttga tattacttct tttcaggcaa tacgaatatt
     1501 attcgcttac atttttttgt ataaatttag ttgttttaaa tttaattgtc tgctacgctt
     1561 gtgatgaatt aattttcgtt ctgcactttt ggacgataaa tttggacaat tgaaaataca
     1621 aaaaaaagaa aggccctgtg agactcggaa ggctggtaac cttcgtcgac gtccacaggt
     1681 ggcattaaga caacctttaa tcccttaatg cgtttacctt tcagtgttac ggtattaccc
     1741 gcaacggatt tagtataaca gatattcaaa agtgatacca ctttttttgg ctgtgttaag
     1801 gttaaaaata cgtgatatta cgatgaatct atgcctaagc ataatgttat aaaaatgtcc
     1861 gtgtggctct ttgccgtatg acgaacgctg aaattagagg gaacgcatgt ttggatgcgt
     1921 tccctctttt ttgtttgtca tgaacgaaaa tcaattctct atttttgaaa aataacaaga
     1981 aaaacttatt aaaaatattt aaagtaagtg ggtggattat tttatgtcat atacaggaat
     2041 tttgagtctc gaagatattt gtcactacgg taaacggtgt accgctacag agaaaatcac
     2101 gaagaaacta tcaactggcc aaagtaaaac cgttgtgcag tgtaagaaat atataatcca
     2161 gaaagacaaa gtctcagagg aaatgattta ttacgctggt aaacaaaagc aaataatttt
     2221 aaaagatcct atccctttaa aagaactata tccaacaatc aaacatgttt atgaccaaaa
     2281 cggtgtactg attggtcgaa gaaaaaatgg agtcttgcgt tgtaccgcaa aagggatggg
     2341 gcgtttaatc agctgaattg atcattctca taacttgtat tttatcgttt ttcgcttgct
     2401 tgaaaatatt gtcgagactt ctaaaagaac ttagaattac tagaaaaata aggagtagac
     2461 ttgatctatc aacaattcct ttcggggggt gacggggtag gtttttacga ttggtaacgt
     2521 aaaaaattgg tcaatcgagt aaatgccctt gtttggatag tggtgaaatg aatttgtgta
     2581 aataatatgc acagagtaaa caagagggaa tttagaagtt agacaagtta gaatagcgcc
     2641 tagattaatc atgagcagct actaagggat ctaggctttg acgcaaactc atggaataag
     2701 gagtaggtct tctcgtaatg gggaggacgc acaagaaatt gtgtcgtgtg ctgcagtaca
     2761 tgtagatact tgcgaggacg ttggtcattg gatcaatcga gcatttaccg atttctacta
     2821 gggtttctcg tttcggacgc cataaacgag tcgatatttt ttatgtattt ttaagtaaac
     2881 gaaaaacgat aaaatatgaa cgagtcctga ataaagtgaa aaaattgata taaaacatag
     2941 agaaaatgaa atttacgtaa tggaggaatg acaaatgaaa aattatgatc cgaatatacg
     3001 attgggcaca catactatta aggtttcttt ccaacgttgg gattacaaag gatttgtgac
     3061 gtttagaaga ggcggaaatt gtaaaggatt agatgtttta gcattagacg aggatgattt
     3121 atactatcaa aaattgactg ataatccaat tggattcggc ttgctacctg aagatgatga
     3181 aggtaatgaa tggtttaaaa tgacgcttac gaatgataat ggagacgaat tatctgttga
     3241 agatacttgg tcatatttga gtgattatat tgtcagcgtt gaaatcattg aatttgtagc
     3301 ggataaagaa gaataaaaac tggaggaata aattttacag ataaaggctt agaagaagtc
     3361 acgacgaata ataaaaaggt agtattacct taggcattga gtaaggaatt catttaggag
     3421 gaaaattaga tggcgcgacc agttttagag gcgatggata tggatacttt gacaaaagga
     3481 aggtatgtac agctgttagc tcgtggttat tcacctaaag atgtattcaa atccctgtct
     3541 aaaggaacag atatggaaaa agaaagatta cgaaaagaat tcgattattg gagaacccat
     3601 aatggaatca aggatttgaa accagcacgg ccagtaatta aacgaaagaa aaagataacc
     3661 caagactgaa gtgtagagcg tatgtgatca taggcttttt tatttttgca aaaaacaagg
     3721 aaggtaggaa aactcatgaa ttatgaagaa atcgaaaaca gaaaaaaagt gtcgaaataa
     3781 atggaagaaa agttgctaaa aacgatgaaa caaaaacacc ttaaaagatt atctgtcatg
     3841 caatatatca atgatatgca gataacagga aaagagaaag cttgtttgtt aggttcaatg
     3901 aaaaactttg aacagttgag acgaacttat gtgaaaacaa gttctaattg tcaactattg
     3961 ttagaagtct catgacattc attaatagaa ttcattttta aaactttttc tatggaaatg
     4021 agaaaaagat tttttgtttt gtctgaaagg gggtagctgg atgagaaaat ggttatttgg
     4081 ttttttagga gtcgctttaa tcgtcttttg cagtgtgttt ggctatgtta gctaccaaaa
     4141 acatgaagga gaggtgttta agcaaaatat agaaaaaaag atgcccgtag atcaaatcaa
     4201 tgcacatgca aagagttata aggaggatgc aacgaacgtc aataatgata tgtctttggg
     4261 gcaaatgttg tccatacaac aagaagcaat cgaaatgggc gtcaataaac aagtatttgc
     4321 acaaattcag attcctgcac ttggtttagc attgccaatt tttaaagggg caaatcaata
     4381 cactttgagt cttggagcgg ctacttattt ttatgaagat gctgaaatgg gcaaaggaaa
     4441 ctatgtccta gcaggtcata acatggaaat gccaggtgtt ttattttctg atattcaaaa
     4501 gttgtcatta ggggaggtga tggacttagt tagtaacgat ggcgtctatc gttacaaggt
     4561 aacgcgtaaa tttatcgtac ctgagtactt taaattaatc gatggcgttc ctgaagagaa
     4621 ctctttcttg tctttgccaa agaaaggaga gaaaccctta ttaacgttgt ttacttgtgt
     4681 ttatacgtca caaggaaaag aaagatacgt ggtacaggga gaactacaat aacaaggttt
     4741 taatcaacgt gagtcgttga aatatgaaat gaggagagta aaaaatggca ataaatcggt
     4801 atgtaaaaaa agctggaatg cttattggaa tgttaggaat cattgcaggc tgctttcagg
     4861 gatatcgagc atatgcagaa gatgtcacgc aaaaaacgcc accagagaag gtcaatatca
     4921 cggttcataa attaatgtac gatcaaggaa cgcaattgaa tgttgatatt gacgggatca
     4981 aaaacgatgg ttatacgcac gatcaatatc ctacaggtgt aacgaaatac aacaaggcag
     5041 attatggtga tgttgagttt acgttaggaa atattacgga tcaagtatta ccgagagaag
     5101 attctgatct aaccaacgcg aaagtggacg agattgtaca agatgtagaa gacaagggat
     5161 ctaacagtga gtacgtcaag aatgcaacca acaaaattac ttcagctgta gatgaaaatg
     5221 gtgagatcac ttttactgat caaccagcct atgtcaattc caaagggaat gtatatgtgg
     5281 tttatgaaag taaatccgct gctggattag tcacacaaaa agcaaaacca atggttgtga
     5341 ttgcgccaat gacagataaa acaggatcag gatttttaaa aaatattcat ttgtatccta
     5401 agaacattgt ttctaagttg agttttgaat taacgaaatt tggtgacgat ggcgcagacc
     5461 aaagcaaaca aaccctttta aaaggggcaa aatttgagtt atacaagggc gaacctggaa
     5521 aaggaacaaa attgggtgat cttgtatcgg atgatcaagg aaagctgact gcgactgatt
     5581 tgacgttagg aaaatactat tttgtggaag ttccttcgga agttgtagtg ggatcagatc
     5641 aagaaccaac agcagatcaa tatttattag gcgcagacgc tcgcaacgat gcgcacaata
     5701 aattaacctt tgaaattacg aatgatggcg tgacaagtga cttaaaagct tcatacgtaa
     5761 actataaagc accagtgatc gataaaacag taacaaatgg aacaggacaa gaacattctt
     5821 tccaaattgg tgacgcagta aattatcaag gaacgattca tattccaaca gacattgcag
     5881 gtggcgcaga cggtatcaca gtaaacggtg tgaaaagtga aacttctcct tacagtgtat
     5941 ttaaatgggg agatacagca ggacagggac tttcttatgt cgctgctaaa gcaaatatca
     6001 aagtaacaaa taaagatgga tctgtggtat taaaagaaaa tacagattat aaaatccaaa
     6061 attcagaaaa tggctttgtg atcgatttta tcgtgaataa tggccaagta agtgatactg
     6121 tagcaagttt acacggacaa gatcttcaaa tgacttataa catgtatgta aatgacagcg
     6181 cagctgttgc caatccatta acaaatagcg tggatttcgt ttataacaac aatccattta
     6241 atcaggaaga acaccacgaa aaaacgaaag ctgacgttgt gacttatggt gcaaaattct
     6301 taaaagtcga tagcggacta tttggaacag gaatcaaagc aacaccgctt gaaggcgcag
     6361 aatttgctgc taaaaacgca gaaggaaaat attatggtgg attagttgat acggataaag
     6421 acggtgtcaa agaagcagta tgggtagacg atgtagcaaa tgcagcgatc ctaaaatcag
     6481 ataaagaagg tcactttgaa atcactggtt taactgaagg tgaatattca ctggaagaaa
     6541 caaaagcgcc tgaaaactat caaaaattaa cgaaagagat ctctttcaaa gtagacaaag
     6601 attcatacaa agaagaaaac cgaatcacga tcaaaaacaa tcaaaaagct tccgtaccaa
     6661 tgaccggtag caacggtttt caaacgtatg tattaatctc ttgcttgttg ctaggagcag
     6721 gggcactttc tgcagttgtt tactttaaga agaaagccta gaaggatcaa aaccaatgat
     6781 tatcaggaag cctaagaaaa agcgaatcat gggtaaatgg atcattgctt tctggttact
     6841 ttcagctgta ggtgtcttac ttttgatgcc tgctgaagcg agcgtggcga aataccaaca
     6901 aaatcagcag attgccgcaa tcgatcgaac aggaacggca gcagaaacgg attcttcttt
     6961 ggatgttgct aagattgagt taggcgatcc tgttggtatt cttacaattc taagtatttc
     7021 tttaaaacta ccaatttatg acggaacgtc cgacaaaatt ttagaaaatg gtgtaggtat
     7081 tacggaagga actggtgata ttacaggagg aaacggtaaa aatcctttaa tcgcaggtca
     7141 tagtggactt tataaagata atctttttga tgatttacct tcagtaaaaa agggagaaaa
     7201 gttttatatc aaagttgatg gtgagcagca cgcttatcaa atcgatcgga ttgaggaagt
     7261 gcaaaaagac gaactacaaa gaaactttgt cacttactta gaatcaaatc ccaatgaaga
     7321 tcgagtaacg ctaatgacat gtacgcctaa ggggatcaac acacaccgtt ttctagtgta
     7381 tgggaagcga gtaaccttta caaaatcaga attaaaagat gaagaaaata agaaacaaaa
     7441 attatcttgg aaatggcttt taggaagtac tgtttttctt tcagtcatga tcattggttc
     7501 gctatttgtt tataaaaaga aaaaataaag gagggtaacc aacatgagaa atagaaaatg
     7561 gctatttgtt tgtgcagccg ctcttttttc tttcactgcc tacacacagt tgacgtttgc
     7621 agacagacaa gaaagcacgg atagcacaga acaaacaatc caaacgtcag atagcagcac
     7681 gattcaaagc agcgatgaaa ccgtcgattc gtcaacagtt gattcttcag aagaacctaa
     7741 aattgctgaa gacgatcaaa tagtcaaaca gaccattcac gttcaaaaga ttatttcttc
     7801 agaacaatta gacaaccagg ggcatgaaaa acaagaagga gtaaatggcg cgaagttttc
     7861 tgtttatgat gtatcggaca ttttacaaaa gatggatgtt aaggatctca ctactgacca
     7921 aattgaatcc caattaaaaa atcgagtgaa aaaactatcc agtgatcaat tgaagctagt
     7981 ttctaatgaa gaaacaaaga caattgatca acaaacaggt gtctttgaat tctcggtaga
     8041 agtacaggca aatcagaaac aagcttatta tattgtcaat gaatcaagtc ctgaaaacat
     8101 ttctaatagc gaggatattt tgctattaac acctgtttct gataaaaacg gtgaattctt
     8161 aaaggatgtg tggatctatc ctaaatcaga agcttcgcaa cctaaagaag aagtaaaaaa
     8221 aatcgtttct actggcgtaa agaaaaactt ctttgagaat tgttgggatt ttgttactca
     8281 cttgttttct agagattaag gaagaaataa aatgaaactg atcaaattat tattattcaa
     8341 tttttcttgt ttaaccgcag tctttttgta ctgcggttta ttattttcta aactatctat
     8401 tttgccaagc taccaactat acctaatgag gattttaaac ataccagctg cttccatgcc
     8461 gctagatatt atggaaaagc tcattaggaa tccattattt actacgatca atttgatcgt
     8521 tattgtcgga atttcactag tcatttataa aaaagagggg atgaagggat gaattttaaa
     8581 cactcgtgga caagacggtt aaaatatgtt tttcccataa tgatgatgtt aggtacattg
     8641 tttgggttaa aaacagccaa tgtctttgct gaaaaagtta ttgtcgatcc gtcaaatcca
     8701 atccagaacg taaagaataa ttttattatt ccaaaagatg ttcctaatgc aaaaacaaat
     8761 attactgtaa acggagcgtc aaaagtttac aaatatcatg ttgatgccaa caaaggtggt
     8821 tttacagacg actacgtagg attagtggag ggaaacaaaa atatacgcta tccttctttc
     8881 caaaaagaat acggtgaaac aaaccttgtt ttagaaggcg taacaaccaa caccaaagtc
     8941 aatattgact atggaaaaat cggtacgtat aacgggaaaa aagtcaatat caagctagtt
     9001 ctatctaata ttcacttata ctcggatacg ttgccgtgga atctactaga taacaactat
     9061 acaaaaactc attttcgaga cgatggctat aaaaatacga atggtgcaat gagtaaatct
     9121 aaaaaaagaa cagtactttg gatctcagac aatcttttct caggaattgt ttaccattca
     9181 acacaaatga atgtgcagct agtagccaca tatgaggacg gtagccccgt tcaattttca
     9241 ggagatacat ttatcagttt taactctttg aaccctgcag gaggaaaaag cacggatctt
     9301 aaaggagaat atgcccacta tgacaaaatg aatacgacag attggtatgt cagaaaagat
     9361 acggttcttt cagaatttaa atctttctac aacaatctga acgtggtagg tggccaccca
     9421 ggaggaagct ctaagctgac acaagcggat aatgatttca ataatttgca tgataaatta
     9481 ggagatccga agtttggtca aggtactgtg tcctttaaaa tatctgaagc aaatccgacg
     9541 tttgtgattg gttcttctaa tgttcaaacc tggtttactt tatcttctgc gacaatcttt
     9601 agtgttgttc ctgatcaacc tgaaaaaaca ggggttgata aaaatggaaa taacgtgaac
     9661 gataaaatgt tgcaagtagg agacacgatt caatatcgaa tcaaacagaa ggtgaatcga
     9721 ttaggagtgg atttactagc ggtttacgat cgatttgagt taatcgataa tttaccaaaa
     9781 gaagtaaatt acgtcgatgc acacgttgaa agtggtacaa ataaaaaatt cgatgtatct
     9841 ggtgaagtga cctatgacaa aacaaaacac caggtaaaat atgcagcgaa agctgataca
     9901 ttaaaaaatc gaatgaagta taacggcgaa acttacgaat tagtgatcaa tgtaaaagtc
     9961 aatgaattgg ccaatcaaaa tagtgtagcc aaaaatcagg gaacgtcgat cattaataaa
    10021 gtagaaaagg atacaaatat cattaccgtt tatttcccta aaattccagt gaaagaagta
    10081 caacaaaatg gaaaagatgt aaacggacga aatgacggta agaagggtac gccgacagct
    10141 cctttaaacg caggatctga agtacaatat ctagtcacac aaaaatggca cacaaaaggc
    10201 gtagacgctg cgtcagatca ctacaaacaa tttagtattc aagatccaat tgaagctcgt
    10261 ttgacatata aagaaggttc tgcgcaagta atagataaga gtaaaggaaa agatattact
    10321 tctgaaggca cactaaccta tgatagcaat tcaagaacgc tgaagtggga agcttccgct
    10381 gacttcttaa gtaacaatct tttagatgga cgagaaattc agctgatatt tacagctaaa
    10441 actccattac aatcagaaaa aaatattgat aaccaagccg tagtagcagt agataatgtt
    10501 tctaataaaa caaatgttgt gacaattggg gttgatccta acttgccaca ggtcattgtt
    10561 cctaaaacag gttctacaca tttagtaacg atttcagcgg tcagcttact attacttgtg
    10621 ttagcaactt ttagttatgc ggttctgaga tacatttaaa ataaaaaaac gaaagaatga
    10681 ataaaatgaa aaagttaata atagtagtta cttccttgat tgccatgatt gttattttag
    10741 tcggatgtag taatgaaaaa aataaacaaa ctaatcaaga taatggcgta ttgaaatcag
    10801 gaactatgtg gaaagaagaa gtaggtggtc ttgtttataa tttgaaaatt atagacgaga
    10861 ctacctggga atactctgag agtgtatggc atccagatcc tgtacaaata acagtcaaga
    10921 ggcaaaaaga ctataaaggt ttagaaagat acaaaatagt agattcagct ggtgttaggg
    10981 aatttataaa caaatctgat tctttattta ttgttgttcc ctatgagaag aatggcgtaa
    11041 aaaaaataat ttttcttgga tctagcaagg atgaaaagcg aacgaaagag aaattgattc
    11101 acgatggatc acaatccaat aaatataagt tacaaaagac tagcgagtga ttgctagtct
    11161 ttttatttgt cctgaaggag gaatcacagt ggcaaaagct aaaacgccat ttgaaaaagc
    11221 cgcgtctaaa atcttagaac gccgcggtgt atctgaaaca cagtggaaac aagaagtcct
    11281 tgaaaaagca caatttgacc tattacgggg aaaagacaag gacttagaag gatatatcta
    11341 tcaacgtgaa cgtgaaaagc ttgttttcga tgaaattatt aaacactaaa aggagcgaac
    11401 aattttatgt ttgaatcaat tacaatgaat tttttaacac aaccgaaagt agtagctgcg
    11461 gttgatattt ttagagcatt acaaactgcc gcaactagtt taaaaaacaa tctgatgatt
    11521 tttgctgctg ctgcggccgt tgcttccatt gttattgggg gtcttttctt cctatttgga
    11581 cgaagaggag ctgaaaatgg gaagatgcac gtaggctatg tattgatggg ggtaggagtt
    11641 attttagcag cagcttctat tgtggtttcg ttatttggat tgtttggaca aacacctcaa
    11701 ggattataag aaagtaaaaa agtaggagta agaagtagtc gatacttttt actccttttt
    11761 tatgaaagga gaatactcat gtactttacg attgcaggca ataccaaaac agataaagag
    11821 ttaataaaaa aagcaacgaa ggaagtagga aagcgtactt cttttttacc gaaaacaatt
    11881 aaatattctg tcattgaaac ggaagaacag ctacatgtgt tagggaaagt actggaacac
    11941 gaaagtcgat cttctgttaa gttgactctc acgttacatg acacagaagg aaaaatagag
    12001 aaagctggta cagaatacgt ttttggccca ctggattatc aaatttcaga aggtttctat
    12061 cctacattga tggatttaat ccgccttgat gtgtttaaag aaacggatga aactatgagt
    12121 gtggaagagt cttatcgaaa cgaaaaactt ttacaagttt tagaagaaga gttagagagc
    12181 gaccaaagaa aagtgaatca agggagtgaa gtcgaagtaa atgaagaagt accatgggaa
    12241 cgaccaatat ttccaaagaa ggagtcaaaa gaaaaagaga cagtctatgt tgacgaacaa
    12301 gctgatattc cgactcagaa atcgatattt gaggaagaga acgatgtgat gggtcaattg
    12361 gaggtagatc cctttgaaga aacaatggag gatgaagaga cggccgaagt agaagttgat
    12421 ccagttgaag cgaatgaaga gtcaacatgg actgaagggg attctcagga atatattgaa
    12481 ccacttatca gtgaagaagt agaaaaaaac gaaatagaga tacaaaaggc aactgtattt
    12541 gattatattt tggatcaata tccgccagag catgaatgga tgaaagaaaa aaacaaatta
    12601 tttttaaatg agctttattc gaaatatcaa ttaccccaaa cctatcaagc atttttagag
    12661 agtaaagaag aattaatctc acagggtaaa ggcacacttt tagaacagtt agagtctgtc
    12721 caatcaacaa attggcatga gcttgcacaa gaagatttat tagccacctt tgaagaacgt
    12781 caacaagaaa cagatcaaga aattaatgag tatgcgacgg aacagtcgtc taattgggag
    12841 aaagcaaaag aggaactaaa taaagaagaa cagcgagtga ttgaagaaga agtacaaaaa
    12901 attaaagagc gatacgaaaa gaaacgcgac aatgcgtatt ccttgtgtgt agcaaagatc
    12961 aataatttta ctcagacgaa tcaagaagcg ttatcgaaag aaaaagaaaa cttgttaaaa
    13021 gaacgtatta aagaacgaaa agaagaattt taccgaggtt tgcgtacaga taagctaaag
    13081 attagcaaag aattaaatga acaactgaat aagctatatc aaacaacgac tgaagttctt
    13141 atggaaaaat acgaaaagat ccagcaagaa ttacaagtgc aaattccaaa atggaaaaaa
    13201 gagtatgaaa ttcaacaaca agaattgaaa gaacaagaag aaaaacaacg gcaaaaagaa
    13261 aaagagcgcg aacaattaga actaaaaaaa cgtgaacagg atcttgcgga acaacaaatg
    13321 gcaatagaaa aacaacggtt aaaccaagaa aaggaaaaag aagcagctgc tcgtaaggaa
    13381 cgtcaagaac aaatggatac attgcgacaa gctcagttaa attatctagc acaacctcaa
    13441 ccaacgcctt cagtagctgc tgttcaaacc ccaatgaaca accaaacaaa tctaactcct
    13501 tcaccacagc gttcctttaa cggatggatg gtgggatgta ttgcaagttt aagcttgctt
    13561 ctaggtggag gaacagtatt tgcttttaat catatcaatc aatcttcaca ggctgattct
    13621 gtggccacaa cgacgtcaat caaggaagaa gcccaagaac aagcaagaaa agagtatgaa
    13681 caacaattag aagaattatt gaatcgtacc aatcagtcaa caacagagtc aagcatggaa
    13741 aatagcaaag agagtgattc tagtaaggct aaagaaggat caagcgattc aactgtacaa
    13801 tcaaacactt ccgaaagttc agaatcaaat gaggtgaaat aatgcgtgtt agagaaacaa
    13861 cgaagcgaaa agacaaacga ttcaatttag aaaagaatag gtatctttct catttctatc
    13921 gctatactcc ctcaggagaa gagctaccag aaaaacatga caaacgcatt tcgaaaaaga
    13981 ttttttatag tggacttgta tacctccctt tagagtattt agtaacaaga gtaccagaag
    14041 ttttcaaccg attggaaatt gttaagggaa gcttacaagg aataaatctg tttcaattac
    14101 aggaaatgcc acaggtcttt cattttgatt cagctggttt ttggaatcca tttactccta
    14161 caactagttt gggtacacgt ttagcaattt cgacagtttg tgtggttcca gctgtactta
    14221 tgggattgaa aatggacatg tggtttcgtc ctctagcaga tggacaaaaa ggggataatc
    14281 gattaatgac cttaaaagaa atccaacaga tttatccgca aatacctgaa acaaaaacta
    14341 cttttccagg ttatggaggt attccaatca cacattacaa aaaatattgg tacattcaaa
    14401 cagatactgt taatacgtgt attgttggta cctctcgatc agggaaaggt cagattgaag
    14461 tgttagccac cattgacaat ttatctcgtg cagaaaaaca aagttcaatg gtcgttaatg
    14521 atccaaaaac agaattatat gttggtagta aagatgaact agaagctaga gggtatgatg
    14581 tatatgcctt taatatcacc gatccactgc aatcaatgag tgataatcca ttggcactca
    14641 tcgtgaaata ctggaaacga ggagacatag atactgcaac acagttaacc aatactttca
    14701 caaatacgat ttattatgat gccaacgctt cagataacaa atactttaac gaaaacgcgc
    14761 agaaagctgt caatgcgctt atttttgcgt tgttagaaca agctgatcaa acaggagatt
    14821 actccaaatt gacaccgaat aatctcgttg agcttctttc tgagattggc ggttttaatt
    14881 attatccaga tccagacaat gaattcaaac agttgaatgc cttagatgaa tttatgaatc
    14941 agttgccacc tggaaacatt gcaaaaaaac aatatggggc aacgaaaatt ggatctgata
    15001 aagcgaaggg aaatatttta tcaacggcaa tcacgggatt gaatccattt actctaacga
    15061 aaattgcaaa gatgacttct caatcaacga ttgattataa atcggttggg tttccaaaat
    15121 acttagattt gaaattacat gaaagtcttt taaatcaacg agtcgtagta gaattttatc
    15181 ataagggaaa gaaatttcat gaagaacgtg tcaaagtagg ctataaagga ttttgtgaaa
    15241 tcaattttga ttgtcattta gttgcaggtg atcaagtttg tttaaaatac gatcatcaag
    15301 gaaaagaata tgtggcttgg tatgaatttt ctcaaagagt attgaaagac gaagagggta
    15361 atatcgttta tcggaaaaaa cgaggagaaa cccatttgcc agaattagaa aaagaagccg
    15421 ttctaacatt agatgaggag aaaagtaact tattagtaga gtctattcgg atgcactata
    15481 ccgataaacc aatggctatt tttatgctta cacctgatta tgatccatct aaccatatca
    15541 ttgttagtat ttttcttagt cagttatata aagaattatc tacgcaatgt gttaagacta
    15601 aaggagataa atgtcaccgc aggattcatt ttattttaga tgaatttggg aatatgccac
    15661 caatggataa tatggaagga atcatgacgg tcacagctgg ccgaaacatg ttgtgggatc
    15721 tgtttattca atcttatcag caactttatg cgaagtatgg agaacaaaac gcagcgatta
    15781 tcaaagaaaa ttgtcagaca catatttata ttatgtcgac agatgataat accatcgaag
    15841 aattttctaa aaaagtgggg aataagacgg ttgaacaaga gaacagtacc atcaattcat
    15901 taggtatgaa tactcatatc aatcgcaatg ttgattcaga tcgtatctta actcctgaaa
    15961 gaatttctac ttttttagaa ggtgaaacga ttgtactcgc tcctttaaaa cgacaagatt
    16021 tgaaaggtca taaaatacgg ccgtatccta tttttaatca tggggaaacg aatcttcctt
    16081 atgcttatca atatattgaa gatttcaatc catcgtggga tatcaatgat atagacatac
    16141 attgtacaca tgcggacttg gatcttaagg ctttacaaat tgattatgat tatttcctac
    16201 cagatgaata tgctagaaat ctctatcatg gactgcatga tcaattagaa gaaaaaaacg
    16261 aagaaaatat gttttataaa atcgttcaat ctcttgagaa tgagacggct aaaaaattgt
    16321 taattcaatt ttacgaagaa caagcagcag atcgacttca agaatatgtt gaaaagttga
    16381 tcaaaaataa agaaatttct gaaatgattg ggaaacggtt gttattggaa tctgaaaagg
    16441 tggtgaaaga atgatcattg gaggaatttt ttctggcata gccgactggt ggtcaggctt
    16501 attcggagaa ggggatgcaa accccaaaac cgtaacgaaa gtcttacaag attatggtaa
    16561 ttatctgcag tatcaagatg tatttagttg gatttggaac acttttctgt ggggattgat
    16621 taaaggatta tataatctca atactttact agaaaaaacc atttatcaaa gctttgattt
    16681 aaaagactta ttgaacgccg ctggggtaaa tgcactattt caaagtttga ttagtaaggt
    16741 attggctctt ttttgtgtcg tcacattaat ttatttaggc ttgaaatttt ttatgagtaa
    16801 acacccacca aaagtcaaaa atatcttggt taatttattt atggccatga tcttgatttt
    16861 tggtgggagt tctttaatcg atgaagggtt aaatatcagt aaaagctttt acggagacgt
    16921 cactgcagca aataaagcag ataaaacggg ttcacctgct tttcaaatta ttcaaaataa
    16981 tgtgatcgat gtcagtacat tactagcaac tgacccgaat aaagtagaat ccctgccaac
    17041 agacaaaaga aatgctttaa cagcgaaaaa ttttaaaaca gcgaatatca atgggattat
    17101 tactcctaaa caagctaaag aaatggcgga taaagataag agtggtttat cagatttaca
    17161 aaaggatcgg ttaagagcgt tacaataccg attggaacta gatgataatg ggaaagaaat
    17221 tcctgttcaa attagtgacg aaggcttagc aaaatatgtc tatacttcag ggtatcgtcg
    17281 atacagtagt aaaccaggta ttatcttagc tggtgaatct tctttggcgg tggcctattt
    17341 atttatccta tttacgatcg ttacttgcat tattgagctg gtatttaaaa aattctattt
    17401 agtgattgcc gcgtcaacgg actttgagac aggccaacgg atgaaaagtg cgatagaaga
    17461 tatttctcaa tccttcttgt tattggcgtt tacgatttta gaattacgaa tctatacatt
    17521 aatgctttca ggtatcggtg atttgcatgc ggcaggaaag atcaatggat tcttgtatgt
    17581 tgttgcttta attgtgctaa ctattgcgct attcaaaggc tctcaatcgg ttacgaagat
    17641 tttcggtgtt gatacgagtc tgaaaaacgg cagtaattct cttcttagca tgtttgcctt
    17701 aggaaatatt gcgaaaaatg tgggtagcgg agctaaaaac cttgcaagtg ctggtaagag
    17761 tggtttaagc catttaaatg atattcgtaa aaatggattt ggccatcgaa aagatgttac
    17821 ccctgataac ggggaagaac aatcagacga taaagctaca actgtaccta atagtaagaa
    17881 aacagtttcc gaaatgttcg ggaaagcgaa aaatggtgtt tctaaagccg cagaaggtct
    17941 tggttacgtc aatgaacgtg ggttaaaagg aacagctgaa gatcttacag aaaaagccaa
    18001 agacacctta gaagagaaat tagacggcac gagagctaaa gaattggctg aagctgtgaa
    18061 gaatccatcc gaagcactag aaaaacaaaa agaaaaagct tcagaagtca aagaaggact
    18121 aaaagatgcg tatggtgaag gacaagttaa tgcagcagta aaagctaata caacaaccga
    18181 aaaagaaaat caagaaggta tagtgattcc ttcagtcaaa gatcaccaag aagcgttgca
    18241 ctctaatgaa aattcgattg aagagaaaaa ttccatagaa gaaagaaatt cagaagaagg
    18301 aaaaaatgga cagttaccaa aaactgatcc agaacaatat cgctataaac ctaacagtga
    18361 ccttgaaaat gagaagcgaa tttcagattt atcaaaagta aatcaagaag acaaagcaga
    18421 aaatgaggga cagttaccaa aaactgatcc agaacaatat cggtatagat ctgttaactc
    18481 cgaaaatgaa aaacgcattt cagatttacc aaaacgaaat caagaagtac aaacggatga
    18541 ggattccatc gttctgccaa atgataatgg aatcgaagtt ggaactgaaa aatcaacgaa
    18601 aattggttta cctaaggcac aaaatttacc aatgaaagat agtcgtttga atcaattcaa
    18661 ggagaatgat caaagctttg ttcaccaatc aactgcaggt actgttcaaa tgaaaccaag
    18721 tcgtttgcct gaaaatggaa atctgacaac tgtttcttac aatttatctg aaagtggtga
    18781 gacagggaat gcgtccgttc aaaatgttgt gacaagagaa gctgcaccaa aacctattca
    18841 aaacgttcat acaggttaca agccagcaaa tgtggcattt actgcaccaa caaaaataaa
    18901 tgtgacaaga gaaactaaaa acaggaacaa tgcattgaaa gaacaactat tgagggatat
    18961 caaacaggat atcaaaccat aaaaggccta caagttaggc cttttattta tatgaaaagg
    19021 agaaatcaat tatggataaa tatataaaca tgaaaaaccc tccaagattt agtggagaat
    19081 ggaagttttt cgcttttttc tttttagatc tattaacgct tggtggctgc tttttttggg
    19141 cgaaaatggt caataatctt gtccacttac cactcttttt tgcactcttg aattatggct
    19201 tatggattgc gatagcgtta gtgattgttt ggcgacccta taataaccca ggtcaacgac
    19261 aaatttttgc gattatcgag tctatttttt ttgcggacaa gaaccattat catgcgttag
    19321 atcctaaccg aaattatcat ggtacgtata aggaggatga ataaatgcga gtcaaaggac
    19381 aaaattcagt tgaaaggaaa tccattttgc agtttggaaa accagaagag cgctctatct
    19441 tggacttatt tccgtataaa tcctgtacag aagagggagt cttaattact agagaagatc
    19501 attttcaacg ttattatcgt gtagtttcta cagacgtgga aggattaaat gaacaagaga
    19561 aactagaacg aatgaatcag ttgaccaccg tcatgcgtac gtatgtgcca acaattaagt
    19621 tagttagttt gaccacagag acggatctaa cggaacaaat cgtgcaaaag cggcaattat
    19681 tagataaaaa tcgtatggaa cagtccttag gaagaaatct acaacgatta aaaaaatatg
    19741 aaaagaaatt agtcgaagaa atccaggaat tgaaacgagc agaacaagaa cgtcctgact
    19801 taagcttctt tttcgtcatt gaaggaaaga caatcaagga tttacaaacc agaaaccgtc
    19861 agttaatgcg atctagtggc attttagggt taaaaccact ctacaaaaaa gaattgatca
    19921 agattctgta tcgaatgaac aatatgaatg atgagtagga atggagaaga gagaatgaaa
    19981 tatccgttga tatggttaga aaaagatgtt ccgaaggaag agaccactag aaaatttcct
    20041 cacactttaa gcctgggtaa gttgggaaaa gggcaatctt ttaaccaagt aaagaatcaa
    20101 acaagaagag gtgactgtac atgttagaag caattaaaac agctttttca ccacaaaatg
    20161 atcaaaaagt acttgatcca ttaaagcaac taggaaatcg ggaaatagaa attttaaaat
    20221 ccaaagggta tgatttagat tttttaaaac aagtgatgcc acaaggtggg ttaaattttg
    20281 atgaagaata tgtgacgtat ggtaatggtt attcacgatg tgtgacagtt tatcactaca
    20341 caaaaaatcc tacgcttttt tggttggcca atctcatgaa caatcctcat acagtggcca
    20401 cactcgatgt tagcacagat gaaaagcaaa aagtgattga tcaaatcaat cgtgccttag
    20461 atgaattaaa tgatcgatca gataatgaac gaaaagcgac tgaccgaaat aaaagcgcag
    20521 aagaatacct ggaactagcg gaatatgctc gtaaattgac ttctaatggg gaaatttcta
    20581 agcaagtcaa agtgagagta catgtttacg gaaacacgat tcaagaagta gatgaacgag
    20641 cgcaggaact gatcgaaaat ctaaaaggga tggattatcg tgcggtgact tatctgcata
    20701 aaaccaaacg agattggcaa tcgatgttta ccatgttcga tgaacaagct gaatggttcg
    20761 gaaatatcaa agggcaatca ctaccatcgt taaacattgg cggaggtttc ccgttccacc
    20821 accaaacgct aaaagatcca ggagggacac aatatgggga aaccatgaca ggcggcccat
    20881 ttgtctggaa tgcgacgtat aaaaatagtg tacggttgtc tactaatacc ttgcttctag
    20941 gaatgatggg agctggtaaa tcgaccgttc ttaaaatgat cgcggaagcc catttagctg
    21001 caggagactt tatttggggc tttgaaaagg gaaaagactt tattcctttc ttaaaggaat
    21061 ataacggtat tatggtgcgt ttagacggat ctgacggaat gatcaatcct ttagagatat
    21121 ttgccacacg gacgtatgat gaagcatcca gtttatatga cgatggatca gtcaaagatt
    21181 tgaagatcaa tgaagcagcg tcctatcaaa cacacttaga caaagtggtc tatcaggtac
    21241 agttagtgag tcctcagcta aaaggaacga tgaaagcaga atttaagacc tacttaaatc
    21301 gtttttatga agagtatgga acagtaccac gcggctttac ttcctcaaat tcgcgttcaa
    21361 atacggagac gcaagtcaca ggtaaagatc cagaagctta tccgacgttc aaagaatttt
    21421 tagacttttt aggacaactg gaattaccag gtgcttccca agagaaaaag aatcgaaaag
    21481 aagaaatgga atccatcgta gaatccttat gtgagacgta tggcatgatt tttgatgggc
    21541 atagtacgat tcgacacctt gaccaacaac agttggtctt ttttgacatt gactctatta
    21601 caggcttaga tcgaggggta caacaatgtc aaatgtacat ggctatgacg ttgatttgga
    21661 atcaggcatt gattcaagga agaagacaac gacgtttaat taaagaaaaa caaatggaag
    21721 aacaagactt caaacgcttc ttggcgatga ttgatgagtg ccataatgcg attaatccag
    21781 attttattga aacggtaaat tatgtcacaa actttcaacg agaaatgcgt aaagtagaag
    21841 caatgactgt tttagctaca caatccccac aagaaatggt gccagaaaat atgtcttctg
    21901 ataacttctc gaaactgaag aaagtctttg aattttcttc tacgaagatc tttatgcgta
    21961 tggatgaatc tattttacgt catatagaag gattagtggg taaatcaatg acgaactcag
    22021 aattagaatc cattcctcaa caaaatcaag gagacgctgt gatcaatttt ggctcaaaag
    22081 aaaccattcg tgttcatttt agtccgaaca aacgtcaatt aaaattgttt gatggaggaa
    22141 aataatggaa aaccaaaatg aaagtttaat caaacagtat gttaagcgtc gtgcaaagcg
    22201 gcgcttattt ttgtgggtgt ttggtacttc tgcaggtttg attactatat tgatcactgt
    22261 gtttgtgacc ctttttctaa tacttgcggc aggttctatt gataattctg attcaagtag
    22321 tggtggcgaa gcttttacag gagaatattc ggaaggctta cccatttata aagaaatcaa
    22381 aggaagaggc cctttttctg atgagattgc gcaatatgct gtaggtgcag cagtgaagta
    22441 taaattatta ccaagtgtga tcctttcgca atacggttat gaatcagcgt ttggtacgtc
    22501 ggcgtccgca agaaatgatc tcaattattt tgggattacg tggtttgatg ggtgtctgtt
    22561 tcctaaagga actgcgcgtg gaattggtgg cattgaaggt ggctggtaca tgaagtttcc
    22621 caactcaaaa gctgccttct cctattacgg ctttatggta gccacacaat caaattttaa
    22681 tgcttgtgtc ggaaataaaa gccctggcgc aagcttattg atcttaggac gaggagggta
    22741 tgccgccgca ggaattactg aagacagtgc ctattataaa aattgtatgt ctattattaa
    22801 tacaaataaa ttgatggagt acgatgagtt tgcgattaaa cactggagag aaggcggcgg
    22861 aactggtggt acgattacag gaagctgggg caatccattc ccaggaagta gcttagataa
    22921 aaattcgttc agtggaggac aactttttgg gaaaaatcca ggaggagaat tccgacctaa
    22981 cgggttccat gatggactag actttggttc agtcgatcat ccaggaagtg agattcatgc
    23041 ggttcatggc ggaaaagtcg tgtacgttgg caatcctggt atttcaggtt tgggtgcgtg
    23101 tgtgatcgtg attaattacg atggcttgaa tatggtgtat caagaatttg caaatagtac
    23161 aggaaattct cgagtgaaag taggcgatca agtgaaagtt ggtcaagtaa ttgggatacg
    23221 agatacagca cacttgcatt taggatttac tcgaatggat tggcgtcaag cacaaggaca
    23281 tgcattcatt gatgatggta catggatcga tccgttacca tttttgaata gcagcaaaaa
    23341 atagatcagg agaaaaaata tggaaaataa aaccttaaaa atcgtcttaa cagctgcaat
    23401 tagcgttagt ttaatcggca atattgcgtt gttttggcag cttaaagaag aacaagagac
    23461 aaatacctat aaaattgaag aagtggctaa aaacgcgtct gataagctca aaaaaaattc
    23521 ttctgaggca caggcgaaga tcgacaagtt aaatcaaacc atcaatgaga aaaaccaaga
    23581 aatcgatcag ctgaagcaac aagatggcac aaaagcaaaa gaggaagtaa ctgaagcaca
    23641 aagaaagacg gcagaagagt tcggtcaatt ggccattgat aaatcattaa gcagaaatga
    23701 attaacggaa aaactaaaag atgtcgcaac ccaagaagtg atcgacaaat taagtcctgc
    23761 agacgatgat caccaacatg acgactacgg aagttactct tttacattag gtgacgtgca
    23821 aacttacgct caaacaagca gtgtaaaaga ggaacaaaat tttgtcgtat ttgttgatta
    23881 tacaatcggc aatcctcaat ttaaagatgt caaaccacaa aaaataaaag gtggattaac
    23941 tgtcactgaa aaacaagtag atggtcaatg gaaagtcaca gactttagtt atttcactcg
    24001 ttaggaggaa gaaaatgagt aagaaaaaag gagcaagaca acgttttaaa aaacgaaaaa
    24061 gttatcttag atggctgggg atctttatga ttctcggctt tttgattctt gctagtccga
    24121 tttacacaca taaaaaggta gacataccag atgaagtaag cacgaacgca tttttaaaca
    24181 cgaaggaact gacgatggtt tcaaaagaaa aaggagcgaa ccagcaatta gtttttgaat
    24241 ttgcgatcga cgatgaagat cagagcttat taaaagaact agctaatctt aattatcgtg
    24301 tagaagtaaa gacagctaaa ggggattatc aagcaataaa agccaaagtg atcaaggtgt
    24361 ctgatgatta ttttgtagtg aagttagcac atgtaccaga agaatatatc gccatgcgtt
    24421 taaccattat tcctgaaaaa attgatccaa aagtggatat gcaagaacca caagatctga
    24481 tttattacgt tcacgaagat aaggttaaag atcaagtgaa agatgaagat tatgaacaac
    24541 atgcgatcaa ttacaaagtg aaaggataca aaaaagaaca aaaagcagca caaaaacaaa
    24601 tggaatcctt ccaagcaacc attgatttga atgaagaatt agtgaagaag ctaaaagatc
    24661 aattgcctta tcaagtcgca gatgatcagg aaaatactga aaacaagatt aatagctacc
    24721 agcaagaaat tgaaacatcg aaaacgcaaa tgaaagatca agaagagatc attcaaaaac
    24781 ttcaagaaaa aattgatcgt atgacaaaag aaaagattta gaaggacagg tggagtgaaa
    24841 aaatgaagcg aacaaacttg gctgacaaag atactttcgc tgagcagaaa gtattgatta
    24901 aagcctatct caaagttgta aaagctaaag aaatatgtcg agaagtgaat ttatctaata
    24961 caacaatatc tgagttgaag aatggtcgaa agaatttaga tactttaaaa ttcagatcat
    25021 ttgaagctct atatgtagct gctaaaaaat attttacagc tgataacaaa taaaaaacag
    25081 gagtatttta tgtgaaaaaa gtatataaaa aatgcttatg aatcagctat atcaccttaa
    25141 ccatttgtta atgagatggg agaaaacatt aaccacgatt ctaacgcaaa catcaagcac
    25201 ataaaacatt taacactcct cctttctggc tgaagatttc aaccaaacag gaagacagcg
    25261 tatcaattat agcatacact ttttcttaaa ttcatttttc atatgacaaa atatttcctt
    25321 ctaatcgaca aagttagaag gattttttat tgtctaaata cacaaataac cttaatttat
    25381 aaagagcata aggaaacgtg ggaacacttt ttaaaaaaag tgttccaata ggctgtgcct
    25441 attacgtttc tcaaaaataa ttgtgggaac aaaatattta aaaataggat agtgaaagga
    25501 tagcaaagga tagtaaaagg atagaagcag gatagcgaaa aggataggct ccttttcgct
    25561 atccttttta aattggagga attaatatgg aagtaagaat aagaaatgta gatgagaaaa
    25621 tcgtaagaga aattgatcga agatgtgacg aactaagtaa ccgaacgggt aataaatgga
    25681 gtcgtaacga ttatttaaag ctactcgttg aaaatgattt tgatcgtcct ttgatggaat
    25741 ataaacaaga taaatttgat caattattaa atcagttaat agataaattt tcttttgttc
    25801 aaagtcataa tacaaaagta ttagaagaat atatttgtca gaataatcaa attatcgaac
    25861 ttttaattga acaaagtaga ggaggagaag tttaacatgg ccaaagttat agacaagcat
    25921 atttattttt atgaaacaca tatagatgtt ctagatgaaa ttattgcaac tcatgcagag
    25981 gttaaaaact atagtgaagc cgttcggttt ctatgtatga attatgattc agaagtggag
    26041 aaaaaagtaa attccaatca agcaaagttg aatgcaatgg gaaaagaaat ttctatttta
    26101 accgaaatgg tttcagagtt tgcggatctc catttgaaag atacagggat tttaattggt
    26161 acaaattcaa ctgtttacca agaagcaaaa gagcgtgtgg aaggcaagat aaaagcaaat
    26221 caaacgaaga aatattctcc taagataaag aaaacaataa gcgaatcagt gactacaaaa
    26281 agtgaagtat ttgatccaac aaggttctta aaacgataaa aattagaagg agaatgtgat
    26341 gagtaaatca cctgcagtca ttctcacttg tcaatttacc ttgcccaata aaaaatcttt
    26401 ttcaacatac attgattata tgacaagaga aaaagcgctg gaagaaaagg aacgacgtac
    26461 gcccgaggaa gaacaggaac tgcgtctaat caagaatgct ttagaggatt tttatattcc
    26521 tgaaggagaa actttttcgg agagtaagac gggtaaagaa ttcagcgaaa cgtcgaatga
    26581 agcgcaatcg ttgatgaaac atggaatcaa ttttgacaag ttagaagaac aagattttac
    26641 caaatatctt tcttatatga cacgtcacta tgcgttagaa caaaagaaag tactgacgca
    26701 tagtgaacaa aaagaatacc aacgcttgaa ccaagcaata aaaaaatatc aaacagagcc
    26761 acacaaaaaa gcttcaggaa atcttcctgg agttttttct atggcttcag acgaagtgaa
    26821 aggaagtgat ctgaaggaga tcaagcaaac cttccaaaga ggacaacaaa aaggctcaat
    26881 catttatcaa gatgttgtct ctcatgatca ttcgtatctt gaaaaaatag gattgtacga
    26941 tcccaaaaca gatactttag atgaagaagg tttaaaagca gctggaagaa aaatgatgga
    27001 gacattgttc gagaaagagc aactgaatga aacaggctac tggatggcaa cgattcaccg
    27061 aaataccaaa catatccata ttcattttgc agttgttgaa aaaaaaaata cgcgtaaacc
    27121 atacactgag attgaaaatg gtgtgagtta tatcgtaccg aaagggaaga gaaggcaagc
    27181 aacattagac gaaatgaaga ctaattatgt acatgagtta gaacgttttt cttatgaaaa
    27241 aaatcgaatg ggtatggaga aacgaaattt attgacacgg aaaagtgatt tgcgtaacac
    27301 cttaaccaaa gtagtgaaag agccagtacg ttatgatcga cacgcaatga gcttattaac
    27361 tgaagtatat aaaaacttac ctaaaaagcg ttcggaatgg cattacgggg atgaaaatcg
    27421 aaccaaactt tcaccataca caagagagaa actcgatgag ttaacccaat atgtgttaac
    27481 aaaagaacct ggatatcaag aatatataca gatttcaaaa gcattgaaag aagaagcaaa
    27541 aagtctttat ggggaaagca agagagaatc aaaggatgca gaaaaaaatg ctctctttga
    27601 tttaaaaaag cgcacaggaa atgccattct aacagaactg aagaaacagg atagtcaaat
    27661 aaaaccttta atagaaagga tggatcagat gcaatctatt tacaatgaac gatcctttcg
    27721 aacacttaaa cagttgccaa cgaatgaata caaatatagt tacgaagaat tcatgaagcg
    27781 caggaaacaa ttccaacaaa gagttgtcac gcaacggagt ttgcgtcaat taaatcgaac
    27841 gattaatgcc catgaagaaa aataccacgc aagtaaagca tacgaagagc aacaacgaag
    27901 aattcaaatg gaacaagaaa gacagtagga ggaatagcaa tgaaacaata tttagatcaa
    27961 tggaaagtta tagaaggatc attaagagaa gaacgaatcg aacaacttcc cgattgttta
    28021 gaaaaagagc atttgtttca gataagagaa atgttgataa acgaacagtt tgatccaaat
    28081 caatttttag tcgttgagta cccagctact ggtgtgtact gttgtaatca tgtgaagggt
    28141 gaaaaatatt ttatcattca agaatatgag ggcaagttag cgccttatta tactacttgg
    28201 gaaatgaatg aagaggggat caataacttc ccgtgtaaaa gcattgaaga gtctatttca
    28261 ctcacagaat gttagttgtt aagtgaataa aagaagtaaa agagtcctga acgtgattgt
    28321 ccaggactct tttttttcac tgaattgttt tccgccaatt cattgagtgg tgcgatttcc
    28381 gtctacatta tatcaaaaga aaggaggaag aagaaatggc ttattcaacg attggagttg
    28441 ttgttgaaaa aagcagagac aatcttgttt ttgtgacaga aattcaaaca ggcagagctt
    28501 ttgtagtcac agacaaagcg gcaaaagcat atcaaagtgg cgatatttta acgttaaatc
    28561 tgactacgaa gacgttcgtc gatgcggcag aagattatcc att
//
LOCUS       DAIGSZ010000037        27232 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.037, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000037 DAIGSZ010000000
VERSION     DAIGSZ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.037"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(161..445)
                     /locus_tag="NOB31_001666"
     CDS             complement(161..445)
                     /locus_tag="NOB31_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973875.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="NOB31_001667"
     CDS             complement(463..1353)
                     /locus_tag="NOB31_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HCI0973876.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="NOB31_001668"
     CDS             complement(1373..1591)
                     /locus_tag="NOB31_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HCI0973877.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3261)
                     /locus_tag="NOB31_001669"
     CDS             complement(1561..3261)
                     /locus_tag="NOB31_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HCI0973878.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3528..4301
                     /locus_tag="NOB31_001670"
     CDS             3528..4301
                     /locus_tag="NOB31_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973879.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="NOB31_001671"
     CDS             complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="NOB31_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HCI0973880.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5017..5119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5125..6096)
                     /locus_tag="NOB31_001672"
     CDS             complement(5125..6096)
                     /locus_tag="NOB31_001672"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCI0973881.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="NOB31_001673"
     CDS             complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="NOB31_001673"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HCI0973882.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8066..8884)
                     /gene="purR"
                     /locus_tag="NOB31_001674"
     CDS             complement(8066..8884)
                     /gene="purR"
                     /locus_tag="NOB31_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HCI0973883.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9051..9875)
                     /locus_tag="NOB31_001675"
     CDS             complement(9051..9875)
                     /locus_tag="NOB31_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCI0973884.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9848..10528)
                     /locus_tag="NOB31_001676"
     CDS             complement(9848..10528)
                     /locus_tag="NOB31_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCI0973885.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10551..11489)
                     /locus_tag="NOB31_001677"
     CDS             complement(10551..11489)
                     /locus_tag="NOB31_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HCI0973886.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11734..12597)
                     /locus_tag="NOB31_001678"
     CDS             complement(11734..12597)
                     /locus_tag="NOB31_001678"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HCI0973887.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="NOB31_001679"
     CDS             complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="NOB31_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCI0973888.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15453..16259
                     /gene="proC"
                     /locus_tag="NOB31_001680"
     CDS             15453..16259
                     /gene="proC"
                     /locus_tag="NOB31_001680"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HCI0973889.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16338..17894)
                     /gene="rny"
                     /locus_tag="NOB31_001681"
     CDS             complement(16338..17894)
                     /gene="rny"
                     /locus_tag="NOB31_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HCI0973890.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18305..19354)
                     /gene="recA"
                     /locus_tag="NOB31_001682"
     CDS             complement(18305..19354)
                     /gene="recA"
                     /locus_tag="NOB31_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HCI0973891.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19463..20704)
                     /locus_tag="NOB31_001683"
     CDS             complement(19463..20704)
                     /locus_tag="NOB31_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HCI0973892.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="NOB31_001684"
     CDS             complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="NOB31_001684"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HCI0973893.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21731..22654)
                     /locus_tag="NOB31_001685"
     CDS             complement(21731..22654)
                     /locus_tag="NOB31_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0973894.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23392..24678)
                     /locus_tag="NOB31_001686"
     CDS             complement(23392..24678)
                     /locus_tag="NOB31_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCI0973895.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24671..25939)
                     /locus_tag="NOB31_001687"
     CDS             complement(24671..25939)
                     /locus_tag="NOB31_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCI0973896.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26191..26652
                     /gene="mscL"
                     /locus_tag="NOB31_001688"
     CDS             26191..26652
                     /gene="mscL"
                     /locus_tag="NOB31_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HCI0973897.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26711..27157)
                     /locus_tag="NOB31_001689"
     CDS             complement(26711..27157)
                     /locus_tag="NOB31_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0973898.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         7741 a         5873 c         4723 g         8895 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
     2701 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
     2761 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
     2821 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
     2881 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
     2941 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
     3001 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
     3061 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
     3121 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
     3181 aaatggaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
     3241 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
     3301 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
     3361 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
     3421 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
     3481 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
     3541 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
     3601 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
     3661 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
     3721 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
     3781 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
     3841 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
     3901 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
     3961 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
     4021 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
     4081 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
     4141 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
     4201 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
     4261 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
     4321 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
     4381 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
     4441 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
     4501 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
     4561 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
     4621 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
     4681 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
     4741 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
     4801 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
     4861 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
     4921 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
     4981 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
     5041 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
     5101 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
     5161 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
     5221 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
     5281 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
     5341 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
     5401 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
     5461 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
     5521 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
     5581 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
     5641 catcaaatga tcgactggaa tatcaaagaa accttggatt tgaactgcat gaaggtccaa
     5701 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
     5761 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
     5821 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
     5881 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
     5941 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     6001 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     6061 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     6121 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     6181 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     6241 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     6301 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     6361 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     6421 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     6481 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     6541 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     6601 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     6661 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     6721 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     6781 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     6841 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     6901 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     6961 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     7021 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     7081 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     7141 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     7201 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     7261 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     7321 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     7381 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     7441 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     7501 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     7561 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     7621 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     7681 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     7741 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     7801 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     7861 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     7921 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     7981 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     8041 aactaagcag ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     8101 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     8161 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     8221 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     8281 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     8341 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     8401 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     8461 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     8521 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     8581 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     8641 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     8701 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     8761 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     8821 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     8881 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     8941 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     9001 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     9061 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     9121 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     9181 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     9241 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     9301 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     9361 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     9421 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     9481 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     9541 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     9601 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     9661 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     9721 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     9781 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     9841 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     9901 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     9961 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    10021 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    10081 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    10141 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    10201 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    10261 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    10321 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    10381 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    10441 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    10501 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    10561 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    10621 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    10681 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    10741 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    10801 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    10861 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    10921 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    10981 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    11041 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    11101 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    11161 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    11221 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    11281 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    11341 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    11401 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    11461 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
    11521 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    11581 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    11641 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    11701 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    11761 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    11821 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    11881 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    11941 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    12001 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    12061 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    12121 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    12181 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    12241 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    12301 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    12361 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    12421 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    12481 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    12541 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    12601 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    12661 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    12721 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    12781 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    12841 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    12901 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    12961 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    13021 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    13081 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    13141 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    13201 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    13261 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    13321 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    13381 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    13441 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    13501 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    13561 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    13621 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    13681 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    13741 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    13801 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    13861 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    13921 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    13981 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    14041 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    14101 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    14161 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    14221 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    14281 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    14341 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    14401 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    14461 aactactgct acatcttgcc gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc
    14521 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    14581 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    14641 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    14701 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    14761 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    14821 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    14881 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    14941 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    15001 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    15061 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    15121 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    15181 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    15241 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    15301 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    15361 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    15421 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    15481 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    15541 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    15601 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    15661 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    15721 tcatttctat tgcttcagga aaatcattaa cagatttaga aacagcgctt gaagatcctc
    15781 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    15841 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    15901 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    15961 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    16021 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    16081 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    16141 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    16201 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    16261 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    16321 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    16381 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    16441 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    16501 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    16561 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    16621 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    16681 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    16741 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    16801 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    16861 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    16921 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    16981 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    17041 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    17101 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    17161 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    17221 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    17281 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    17341 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    17401 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    17461 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    17521 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    17581 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    17641 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    17701 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    17761 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    17821 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    17881 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    17941 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    18001 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    18061 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    18121 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    18181 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    18241 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    18301 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    18361 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    18421 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    18481 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    18541 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    18601 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    18661 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    18721 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
    18781 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    18841 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    18901 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    18961 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    19021 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    19081 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    19141 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    19201 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    19261 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    19321 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    19381 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    19441 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    19501 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    19561 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    19621 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    19681 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    19741 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    19801 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    19861 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    19921 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    19981 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    20041 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    20101 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    20161 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    20221 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    20281 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    20341 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    20401 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    20461 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    20521 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    20581 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    20641 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    20701 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    20761 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    20821 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    20881 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    20941 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    21001 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    21061 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    21121 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    21181 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    21241 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    21301 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    21361 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    21421 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    21481 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    21541 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    21601 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    21661 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    21721 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    21781 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    21841 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    21901 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    21961 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    22021 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    22081 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    22141 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    22201 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    22261 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    22321 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    22381 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    22441 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    22501 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    22561 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    22621 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    22681 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    22741 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    22801 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    22861 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    22921 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    22981 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    23041 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    23101 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    23161 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    23221 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    23281 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    23341 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaatactgg tttattttgg
    23401 tctcatgtaa aactcgctga aggcctcttc acttataaat gcttccccag ctgccagtac
    23461 gtctttcatt tggatcgaat cgatgatttc aggaagatca aataaagttc gatcgccaaa
    23521 taaactttgc gtaaattgat tggcaatata ttcgatcgaa tttaatgatt ggaaatattg
    23581 tccaagcatt ttcttcttca gcaaatcgag atttgtttct gacacttccg gatcatcagc
    23641 gaatccaaga atgatttctt tgactttttc tgctgctttc tctggttcgt ccgtatctcc
    23701 gctgaagtcc gcaaagtgaa attcacgatc caagctgaat tcaaaaccaa agctgtcatc
    23761 gataattcct tgattgtaca tcgctagata gtttcgagaa gtattgccta aaatcatttg
    23821 gaacaacaga ttgattgctg ttttatagcg taacagttct gttccttctt gcggcaatgt
    23881 gtctaatcct ttaataccaa gtacaaattt atctcgtgta atggctgctt ccaatgcact
    23941 ttgtttgatg atttcttttg tgttttcagg gaaataacgt acaatttctt gctttggagg
    24001 gaaatttttt gcttcttggt tttcccgaat aagtttcatc aatttctcag gctccatctt
    24061 accaactaca aataaaacca tattgcttgg ctgataaaac gtccgatagc acgtatacaa
    24121 gtcttgagct gtgattttgt cgatactttc aaccgtgccc gcaatatcga tatgcaatgg
    24181 gtgtgtagga tacaagttat ttagtatgcc aaaaaacatc cgccagttag ggtcgtcttc
    24241 atacatttgg atttcctgac cgatgattcc tttttccttg tttacagttt cttctgtgaa
    24301 gtaaggtgct tgtacaaaat cgatcagagt cgtcagattc ttttctacct gatccgtcgt
    24361 agaaaacaga tagctggttt tcgtaaaact tgtgaaagca ttggcggaag ctccttgttt
    24421 cccaaataat tgaaagacat caccatcttc tttttcaaac aacttatgtt ctaaaaaatg
    24481 ggcaattcca tctggaactt tcaccttttc tttttcacca tagggaataa attcgttatc
    24541 gatcgaacca taattcgtac tgaacaaacc atatgtcttg tgatagtcat ttttaggcaa
    24601 caaatacacg gtcaaaccgt ttggcagtac ttcatgataa agtgtttcat tgatttgctc
    24661 atattctgtt ttattcattt gcatttcctc ctgctaaaaa gaagattgcc tgcaattcga
    24721 tttgctcagc tacttgttgt atctctttga tcgttacgct ctccatacgt ttcaaccatt
    24781 cttcatcaga taattttgtt tccggcagcc agctgtccaa aaaagaagct tcgattgccg
    24841 cttgcggaga gtctagagaa agcagatatt ggtttctcag cattgctttt gtctgagaca
    24901 gttccaactc tgttatttca ccatttcgca aactttctaa ttgctcgtga atcagatgaa
    24961 gtacttgatt tcggttcttt tcatcgatac cggtttggac actcatgaat cctcggaacg
    25021 tatccacgct actagaggca taataagcta gactttcttt ctctctgaca ttcatgaaaa
    25081 gtttagagtg aggaaaaccg ccaaataaac cgttaaagac cattagcgca aaacgttctg
    25141 gttcatcgta atacacattt gtctgataag ctaggttcag ctttgcttga acgattggct
    25201 cacgtacttg tcgttccttc acgatattca cttgaggttg ggtataaaac agatctggat
    25261 aaactgtttc ccgcgactca aatggtaatt gcccaactgc ttcagctgct ttgtccggat
    25321 caacatcgcc gacaacaaaa atgtcgattt gatcatttgc catcatttct tgatagtagg
    25381 acgctagcga actagcagtg atcttgtcca aatcttcgac tacgcccaac cctgggatct
    25441 tttgttccgg gctgttttca aaataaagtt cttgcaaggc ataggaagca aaagtttgtt
    25501 tatcttcctt caaactttcc aaatatagac gcagattgtt cttttccaag tcaaacgtca
    25561 actgatcaaa ctgatgattt ttaatatttg gataaaataa aacctctttt aaaaaatcta
    25621 ccgcttgaga aaaaaggttt ggatcattga catattcacc attcacaaaa ctgatccctg
    25681 cgtttagcca atgtaaattt cctttttttc taactgataa tccaaagctt gcgccataaa
    25741 gctctgcaag ttgcgcactt aactttgtct gatccggata attcaaacta tttgtttcca
    25801 acatgctgct gagaagtgaa cgtttcgtga tgacttcttg ttgcagacgc gcagtaaaac
    25861 ggataaaaat ccggatcgtt ttgtattgtt ttgttggtaa gacatgaaga ttcacgcctt
    25921 ctgccaattg atacaccata tttatatgct ccttttcaca gttgattgcc cgcttactct
    25981 tttaatgggt caacctgcct tttttactta ttcctctgct tgaaatttat aagttcaggc
    26041 aattcgccgt tttttctaaa tgatgttaca ctttatagta tagcatagat gttttttatc
    26101 aaaagaaaca gacggctaaa agcgtatatt gtttttttat tttttatttt tcgatatact
    26161 aaagacaaat aaaagaaggg agggtcattc atgatcaaag aattcaaaga gttcatcatg
    26221 cgtggagatg tcttggatct tgctgtcggc gttgttattg gtagtgcgtt tacaagcatc
    26281 gtaaaccaag tggtgcaagg cttgatcaca ccactaatag gttggtttgt cgcaatgatc
    26341 acaggtactt ctgatttaga aggagcactt tcaattcttg actggtcgcc gacaaaaggc
    26401 gtcacatttg cgtttggtaa cgttattagt gctatcatta catttctgat cactggtttt
    26461 gtcttattct tagttgtcaa agcggcaaac cgtgcgaaga atttacgctc caaagaagag
    26521 caagtggaag tggaagaaac tcctactgca gaagattatc ttagtgacat acgcgatctt
    26581 cttgccaaac aagtggcaga agacaataca catccagtag agcaaacaaa tctttccgat
    26641 acttctaaat aataaagaat ctaaaaaaaa gaaagccgat tttcagtgtc ggctttcttt
    26701 ttttagattc ttaacttgct acttgttcct ttttcatgtc gatatgtgga atatcatctt
    26761 ccaaatacac atctgagatt gccttgaatc caaacgactc ataaaaagct tgtaggtatt
    26821 cttgtgcgcc gatcacgatt ggtttttctg gaaaattttt ctggatcatg ttaatcgttt
    26881 cttgaacaat ctttcttcct aaaccatctt tacggttgtc ctgatgaaca aggacacgtc
    26941 caaaatggat actctccgct tcttcatata ctcgcgtgta ggcaaggatc ttcccatcag
    27001 tatcttgaaa aaacgtatgc caagcttgtc catcaatgtc atcaacttct tgataaggac
    27061 actgttgttc cacaacaaaa actgcgattc gttctttgac gatcgcgtaa aactctgctg
    27121 ttgacaattc ttcaaatttc tttacctgat attccactaa gcaaacgccc cctgcttttt
    27181 tattcttagc ataccgattc gcacacaaaa aagcaaacga accttacgaa tc
//
LOCUS       DAIGSZ010000038        27065 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.038, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000038 DAIGSZ010000000
VERSION     DAIGSZ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.038"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            111..1253
                     /locus_tag="NOB31_001690"
     CDS             111..1253
                     /locus_tag="NOB31_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCI0973899.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            1246..1452
                     /locus_tag="NOB31_001691"
     CDS             1246..1452
                     /locus_tag="NOB31_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HCI0973900.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            1531..2724
                     /locus_tag="NOB31_001692"
     CDS             1531..2724
                     /locus_tag="NOB31_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0973901.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            2929..4068
                     /locus_tag="NOB31_001693"
     CDS             2929..4068
                     /locus_tag="NOB31_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HCI0973902.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            4061..4861
                     /locus_tag="NOB31_001694"
     CDS             4061..4861
                     /locus_tag="NOB31_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0973903.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            4861..5688
                     /locus_tag="NOB31_001695"
     CDS             4861..5688
                     /locus_tag="NOB31_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCI0973904.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            5666..6400
                     /locus_tag="NOB31_001696"
     CDS             5666..6400
                     /locus_tag="NOB31_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0973905.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            6500..7366
                     /gene="rfbA"
                     /locus_tag="NOB31_001697"
     CDS             6500..7366
                     /gene="rfbA"
                     /locus_tag="NOB31_001697"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HCI0973906.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            7380..7952
                     /gene="rfbC"
                     /locus_tag="NOB31_001698"
     CDS             7380..7952
                     /gene="rfbC"
                     /locus_tag="NOB31_001698"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HCI0973907.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            7974..9002
                     /gene="rfbB"
                     /locus_tag="NOB31_001699"
     CDS             7974..9002
                     /gene="rfbB"
                     /locus_tag="NOB31_001699"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HCI0973908.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            9100..9951
                     /gene="rfbD"
                     /locus_tag="NOB31_001700"
     CDS             9100..9951
                     /gene="rfbD"
                     /locus_tag="NOB31_001700"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HCI0973909.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            9985..12018
                     /locus_tag="NOB31_001701"
     CDS             9985..12018
                     /locus_tag="NOB31_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973910.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            12062..13342
                     /locus_tag="NOB31_001702"
     CDS             12062..13342
                     /locus_tag="NOB31_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HCI0973911.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            13552..14358
                     /locus_tag="NOB31_001703"
     CDS             13552..14358
                     /locus_tag="NOB31_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973912.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            14370..15590
                     /locus_tag="NOB31_001704"
     CDS             14370..15590
                     /locus_tag="NOB31_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0973913.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            15580..17166
                     /locus_tag="NOB31_001705"
     CDS             15580..17166
                     /locus_tag="NOB31_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI0973914.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            17205..19343
                     /locus_tag="NOB31_001706"
     CDS             17205..19343
                     /locus_tag="NOB31_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0973915.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVCPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(19711..20694)
                     /locus_tag="NOB31_001707"
     CDS             complement(19711..20694)
                     /locus_tag="NOB31_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HCI0973916.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            21072..22463
                     /locus_tag="NOB31_001708"
     CDS             21072..22463
                     /locus_tag="NOB31_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCI0973917.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            22479..23519
                     /locus_tag="NOB31_001709"
     CDS             22479..23519
                     /locus_tag="NOB31_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCI0973918.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            23538..24623
                     /locus_tag="NOB31_001710"
     CDS             23538..24623
                     /locus_tag="NOB31_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HCI0973919.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            24656..25618
                     /locus_tag="NOB31_001711"
     CDS             24656..25618
                     /locus_tag="NOB31_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCI0973920.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            25611..27038
                     /locus_tag="NOB31_001712"
     CDS             25611..27038
                     /locus_tag="NOB31_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HCI0973921.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
BASE COUNT         8903 a         4364 c         5492 g         8306 t
ORIGIN      
        1 ccccaaacct gtgagtagta atgagaggtt ttaagaagat agtacatatc acactttttg
       61 aaaggtggtt tacaggtatt tcaaggctat tgtgggattg gaggaataca atgaacaatt
      121 tagaatttgc acttgaaatg aagaacaaac gtcttgccag cggtctttca caaggagaac
      181 ttgcaagtct tacccatgta tcaagatata gtatcaaccg ctttgagaac ggaaaagcta
      241 acgccagcaa ggaaacacag aacattatcc tgcgttgtct gaattactat atctgcgata
      301 agccttttta tctgctcgtt gattatctgt ctgtccgttt tccaacgact gacgcattgg
      361 aagttatccg aaaggtgctt ggcatgaaag cagattattt tatccattat gactatgggt
      421 attatggcta taaggagcat tatgcttacg gggaaatcaa ggtcatggct tctgatgatg
      481 aacacatggg cgtattttta gaattaaaag gggcaggctc acgcaacatg gaatatgtct
      541 tacaggcaca gaacagggac tggtattcat tcttaaaccg ctgtcttgac tgtggcggtg
      601 ttatccgacg ttttgacttg gcaatcaatg atatgtgcgg tctgctggat attcctgtgc
      661 tatctgaaaa atacagaaat ggtggtgcgg aatgtcgctg taaaaactat gaaaatgtac
      721 aaggtggaaa attaagcgga aaaaaccgta atttagcaag taccctttat atcggctcaa
      781 aggcaagcac aaaatatttc tgcctgtatg aaaaacaaaa ggaacaggca acgaaaaaga
      841 aacataccga tattatcaac cgttttgaaa ttcgtctgcg tgacaaaaag gcggtacagg
      901 cagttgaaga actgttattg acgtataacc ctcatgggct ggtgttttat ctcattaccg
      961 attttgtgga atttcctgac tatccattgt gggagatatt catttcccat gacagtttac
     1021 cttttgaaat gaaccctgta cctgtcaata tggaacgcac tctgcaatgg ctggaaagac
     1081 aggtcatgcc gtcaatcgtg atgatagagg aaatcgacag gctgacaggt tcaaactaca
     1141 tgaaaatgat tgatgaatgt acccaccttt ctgaaaaaca ggaaatgctt gtggaacaga
     1201 tgtgtacgga catatcagac gtaatcgaaa gtgagggggt gttttatgag taatacacag
     1261 gatattcccg tatgggaaaa atacaccctt accattgaag aagcgtcaaa gtatttccgc
     1321 attggagaaa acaagttaag acgattggca gaggaaaaca aggacgctgg ctggctcatt
     1381 atgaatggca accgcataca gattaaacgc cgacagtttg aaaaggttat tgataaattg
     1441 gacgcaatct aatgcaaatg agccttgtat gtgttatgat gaacacaagt catatcaagg
     1501 ctctttccaa caaggaaagg agcagacacc atgaaagaaa aaagacggga taacaaaggt
     1561 cgtatcctgc atactggaga gagccaacga acagacggaa aatacttata taaatatgta
     1621 gacgcattgg gaaacacaaa atatgtgtat gcttggagat tgacacccac agacccgaca
     1681 ccaaagggaa aacgggaaaa accctcactt cgagaactgg aacagcagat aagacgggat
     1741 attgaggacg gtatcgacag cacaggcaag aaaatgacgc tttgccaact ctatgccaaa
     1801 cagaacgcac agaggacaaa tgtgaagaaa agcacacaga aacaacggga acaactcatg
     1861 cggttattaa aagaggacaa gttaggtgct aggagcattg atacgataaa accctctgac
     1921 gctaaagaat gggcgttacg catgaaagac aaaggctttt cctacaatac cattaacaac
     1981 cataaacgct cgttaaaagc gtcattctac atagccatac aagatgatta tgtgaggaaa
     2041 aacccttttg atttcaagct aagtgaagtc atagaaaatg ataccaaaga gaaagtcgca
     2101 ttgacagagg aacaggagca agccttattg tcatttatta agacggacaa cgtgtatcac
     2161 aagcattatg atgatgtgct gatactgtta aagacaggac ttcgtatctc ggaactgtgc
     2221 ggactgacag tagccgacat tgatttcaag aatgaagttg tgattatcga ccaccagtta
     2281 ctaaagagta aggaacaggg ctattatatt gaaacgccta agacgaaaag cgggataagg
     2341 caagtgccat taagcaaaga aacgatacag gcatttcaac gggttatcaa cagccgacca
     2401 aagataaagt cgatagaggt agacggacac agcggttttg tgtttatcaa tccgaaaggt
     2461 aatccaaaag ttgccattga ttataacgcc ttatttatcc gtatggtaaa gaaatacaac
     2521 aagcaccaca aggacaatcc cttgccacat attacaccgc atacgctacg ccatacattc
     2581 tgcacaaggc tggcaagcaa gaacatgaac ccgaaagatt tacagtatat catggggcat
     2641 tcaaacatca gtatcacaat gaactggtac gctcatgcgt ccatagatac cgcaaaatca
     2701 gaggttcagc gtctaatcgc atagaagtat ttaccacgat tttaaccacg attgacaggg
     2761 aaaatataag aagatagacc tagatatgcg aggtttacca caaaagcaaa atgcccgtag
     2821 agccgataaa ataaggcttt gcggacattt gagaagatat aaaaagatag tcaaaaagac
     2881 atatataatt tataataatt atgactctta attaaagtag gtgcccatat gcttgtttct
     2941 tttagtatgg ttataagatt ttttctgaca attttattat cactgatatt aacacctgta
     3001 ttcaaaatca tttcagtaca aacaggtatg gtcgacaaac caaatgaaag aagaataaat
     3061 aaagttccaa tgccttcagc gggcggactg cctatcttta tttcatttgt tatatcgact
     3121 ttattcttat tccgtaaaat tatccctcaa tcgtatattg taccgatctt gattgcttct
     3181 ttagtaatca tagtcacagg agtgctcgat gataaatatg agctgacacc taaacaaaaa
     3241 agtataggga tcttgattgc ttctcttatt atttattttg tagcagatat acgtattgat
     3301 tccttcacgc ttccttttat tggatatatc caactaggct ggcttagttt tcccgtaacg
     3361 attttttgga tcttcggtat cacgaatgcg gtcaatctga ttgacggttt ggatgggctg
     3421 gcggcaggga tttcattgat cggtttaatt acgataggaa tcattggata ttttttcctc
     3481 catgcttcta cagtgtatat tccagttgtt attttctgtc ttgtagcaag tattatcggt
     3541 ttttttcctt acaattttta tccggcaaag atttatttag gcgatacagg agctctattc
     3601 ctagggttta tgatggccgt cctttcacta caagggctga agaacgtgac ttttgtttca
     3661 tcgatttctt tgctgatcgt catgggagtg ccggtaacag acacgttttt tgctatcatt
     3721 aggagaaaag caaaccgtgt ttctttttct acagcagata aaaaacatct tcatcaccga
     3781 ctaatcagtt taggctttac tcataaaggt gctgtcctga cgatttatgc gatggctttg
     3841 atgttttctt tcacagctat ggtcatgaat tatactggaa gaatcggaac gatcatattg
     3901 attattgcca tgttgtttgc tgcaatttta ttatttgaat tgattggtct gatcaatgag
     3961 aaacatcagt ttattttaaa aacattgcga tttttaggga ataaagagta ccgtacgcaa
     4021 gtaaaacaga aatatttgaa gaaatggaac cgtcatatag atgaataaca aattaaacca
     4081 gccgatcctt attagtattg tgacggcaaa cagtgataaa atttttcgga cactagataa
     4141 ttttatttca actgtaaaag atgaaacagc agtaaaaatc cgaatttttg acaacaattc
     4201 acttcccgag tacaaaaaaa gactaacaga gtataggaaa tatccctaca tcgatatcta
     4261 ttttcatgat gaaaattccg gatttggtta tggacataat cacaatctga tagctagcga
     4321 ttctcgctat ggcattattt gtaacccaga tattttagtg gatgaagaga cagttacagc
     4381 attggtcttg ttattgaaag aacatccgga atgtgcgatg ttagcaccta agattcttaa
     4441 tgaagatgga acaactcagc acctcatccg tgagcagctg gctgtttttg attacgtttt
     4501 gcgctttgtg cctttcaaat gggtcaaaaa aaagtttgac aaacgactgg ctgtgtttga
     4561 atgccgagga ttgcctactg atgctaatag ttatgtacgg atgatctcag gtagttttat
     4621 ggtagctgat attgataaat ttaaagagat aaaggggttt gatgagcgtt tcttcatgta
     4681 ctttgaagac aacgacttgt gtttgagttt tgaaaaagca ggttacaagt tattgtacac
     4741 acccttttat gcagttatcc atttttacgg gaagggtgcg catcgaaatg caaaactgtt
     4801 tcgcgtgttt ttgacttcta tgatgaaatt tttcaataag tgggggtggc gttttttctg
     4861 atgaaaccag aaatattagt agtcgttgtg ctttatcagc aactattcag tcaatctcca
     4921 gcttatggac cattaagcaa agcacttagc gaaaagcaaa ttcagcttat tatttacgat
     4981 aatagtcctc aaaggcagca aaatgagctg tttgaaaaag aaaatatcgt ttatcatcat
     5041 gatccgcaaa atcctggttt agcggtggct tataattttg cgttgtctca agcagatgaa
     5101 ggaacacgtt gtctcgtcac tctggatcag gatacgaggc tagtcgacga ttattttgaa
     5161 ctattgcgta aagtaacctt tacagatgaa tgtgttgctg cagttccgat gattttttct
     5221 gggagccgac aagtttctcc cctatattca gatcgttata tcaatcgtac agctcaagca
     5281 gtagaagttg aaggcccaac agctgaacga atcatggcaa tcaattcagg tgttgcctgg
     5341 tctgtcaaat ttctaaaaaa gattggcggg tttaatcctg ctttttcttt agattttttg
     5401 gatcattggc tgttttggaa agtggatcag ttggaaaaaa ctgtggagat ccttcctgta
     5461 cgaatggaac atgatctttc ggttttagac tatgaaaaag tttcaagtaa tcgataccgt
     5521 tctattttac aagcagaaaa tcgattttat catgaatatg atcaaaggca tttatccagt
     5581 caccgacgac aattattgtt aagaacagct aaacagttct tgaccgtcaa aaaccggcat
     5641 atctggcgga tgactttgcg ctcatatgtt aagaattgga aggtgtgaat tcgtgcgttc
     5701 ggtttgtata gctaccttta atggaggcag atatttaaga gagcagttag atagtatttt
     5761 atctcagctt tcagcagaag atgaagtagt catttctgat gatgggtcag tagatgatac
     5821 atgggatata ttaactgaat acgcagaaaa agataagcga atccagcttt tttcggggcc
     5881 tcgtcaagga ttgatcgcta attttggtta tgcgatccag cagacgaaag gagatctaat
     5941 ctttttggca gaccaagatg atgtttggtt ggagacaaaa gtgaaaaaga tcactgacta
     6001 ttttgagcag aatccggatc agctagtagt agtttctgat ttaatcattg tggacagcga
     6061 gctgcaagag atccatgatt cgtatttttc gtttcgaaat tccaaagaag gatggcttaa
     6121 taatgtgata agaagtcact atattggtgc tggtatggct ttccggtctt ctttaaaacc
     6181 cgatattttg ccgatcccgt cagaagtgcc gatgcatgat atgtggattg gtttgctggg
     6241 aggaaagaag actgggttcc taagagaacc gttaactctg taccgaagac atgatttaaa
     6301 cgcgagtgag attgaaacac attctaaatt acggcaaaaa atttcttggc gtgttcatct
     6361 gattacggcg ttgatcaaac gaaaatggtt taaacgttga taaaagatgt ttaaatcctt
     6421 aatatttcca tgacaaatat aacaattgat gagataataa caaagtgaaa tttgaaatca
     6481 aaaaggagag cagatatcca tgaagggaat cattcttgct gggggcagcg gaacacgtct
     6541 gtacccttta acaaaggcaa catcgaaaca attgatgccg atttatgaca aaccaatgat
     6601 ttattatcca atgtctactc tgatgttggc gggaatcaaa gaaattctga ttatttcaac
     6661 gccacaagat acaccacgtt tcaaggaatt atttggaaac ggaaatgatt taggactgca
     6721 gatcgaatat gcagtacaag aaagtccaga tggattggca caagcgttta tcattggaga
     6781 agaatttatt ggagatgata gtgtctgctt ggtattaggg gacaatattt actatggtgg
     6841 cggtctgtct aaaatgttgc aacgagcagc ttcaaaagat acaggcgcga cagtatttgg
     6901 ctatcatgtc aatgatccag aacgctttgg tgtagtagaa tttgatgaga atatgcaagc
     6961 tttgtcgatt gaagaaaagc ctgctcagcc aaaatcaaat tacgctgtaa ctggccttta
     7021 tttttatgac aatgaggtaa tttctatcgc taaaggtatc aaaccttcag aacgtggaga
     7081 actagagatt acggatgtca ataaagcata tttggataaa ggaaaactat ccgtagaact
     7141 tatgggacgc ggatttgctt ggcttgatac aggaacacat gaatcattgc ttgaagcatc
     7201 tacctttatc gaaacaattg aaaaacgtca gaacttaaaa gtggcttgtt tggaagaaat
     7261 tgcttaccgt atgggctaca tcgataagga acaattgctg gcccttgcac agccattgaa
     7321 aaaaaatcaa tacggtcaat atttattgaa tttggccgct gaataaggag tccttacaga
     7381 tgaaagtaac agatacaaaa ttaacagatg tcaaaatcgt agaaatggac gtctttggcg
     7441 atcatcgcgg tttcttcaca gaaagttatt caaaagcaaa atttgcagaa catggattga
     7501 aatatgactt tgttcaagac aaccattcac tatcagctga agctggtgtc cttcgggggc
     7561 ttcatttcca aaaaggagaa gctgcacaga caaaattgat tcgggtagtc actggagcag
     7621 ttttagatgt agtagtggat atccgcaaag gtagcccgac ttatggtcaa tgggacggat
     7681 ttatcttatc tgaacataat catcgacagt tgcttgtacc taaaggatat gcccatggat
     7741 tcgttacttt gacaccaaat gtgaacttcc tttataagtg tgataattac tataatgcag
     7801 aagcagatgg gggcatcgca tttgatgatc cagatttagc gattgattgg ccaattgatc
     7861 catcaagagc gattatgtcg gaaaaagatc accgtcatcc gacattaaaa gaatttgaag
     7921 cagaaaatcc atttgtttac ggagaaatct aagaattaag gagaaatttt cttatgaaaa
     7981 acatcattgt taccggaggt gccggattca tcggctctaa tttcgttcat tacgtggtaa
     8041 acaatcatcc agaagtgcat gtcactgttt tggataaact gacttatgca ggaaacaaag
     8101 agaacttggc tggacttcct agcgatcgcg tagaattggt cgtaggagat gttgcagatg
     8161 cagaattagt ggaccgtcta gtaaaagaag cggacgcagt tgttcattac gcggcagaat
     8221 cccataacga taattcatta aaagatcctt tcccatttgt acaaacgaat atcattggta
     8281 cgtatacact tttagaagct tgccgcaagt atgatgtacg ctatcatcac gtatctactg
     8341 acgaggttta cggcgatctt ccattacgtg aagacctgcc aggacatggg gaaggcgaag
     8401 gagaaaaatt cactgcggaa acaccatata atccttcaag tccatattct tctacaaaag
     8461 ctggttcaga tctgttagta aaagcatggg tgcgttcttt tggcttacgt gcaaccattt
     8521 caaactgttc aaacaactat ggtccttatc agcatattga aaaatttatt cctcgccaag
     8581 taacgaatat cttaagcggt attcgtccaa aattatatgg cgaaggaaag aatgttcgtg
     8641 actggatcca tacgaatgat cattcttcag cagtgtggct gattttgacg aaaggcagaa
     8701 ttggcgaaac ctatctgatc ggtgcagacg gtgaagaaga taataagacc gtgatggaat
     8761 tgatcttaga aatgatgggt caaccaaaag atgcgtacga ccatgtaaac gaccgtgcag
     8821 gacacgactt gcgttatgca atcgattcga caaaattacg ggaagagtta ggatggaagc
     8881 ctgagtttac gaacttccgt gatgggttgg ctgacacgat caaatggtac gaagaacatg
     8941 aagactggtg gaaaaaagaa aaagaggccg ttgaagcagc atatgccaaa aatggacaat
     9001 aatacagaga aaatgtcact gtattaatgg aaaaacacat gtgaggcagg cgctcgcctg
     9061 tctctttttt aaaataaaaa tcaaggagcg gataatcata tgtttttatt aactggagga
     9121 aatgggcaac taggtacaga attgcgccat ttattagatg aaaaaaatct gcaatatgtt
     9181 tcaacagatg caaaagactt ggatatcaca gatgccgaga aaacaatggc ttacatcaca
     9241 gaattaaaac ctgatgttat tttccattgt gcagcttaca cagcagtaga taaagcagaa
     9301 gaagaagcaa aagaattaga tgagaagatc aatgttgatg gtacaagaaa tgtagcactt
     9361 gcagcaaaag ctgtgaatgc tcaattcgtc tatatcagta cagactatgt tttcgatgga
     9421 aaaaacaaaa atgtagaata cgaagtagac gaccaaacga atccactaaa tgaatatggt
     9481 cgtacgaaat tattaggcga aaaagcagta gaagagattt tagaagacta ttatatcata
     9541 cgaacttctt gggttttcgg gatctatgga cacaatttcg tcttcacgat gcaacgccta
     9601 gcggaaaccc gcgacaaact gactgtagta aatgaccagt ttgggcgacc aacttggaca
     9661 cgtactttgg cagaatttat ggtatatgtc atcgaagaaa aagcaccatt tggtatttat
     9721 catttgtcga acgaaaatag ctgttcttgg tatgaattcg caaaagaaat attgaaagat
     9781 acagatgtag aagttgcacc tgttacgtca gaagaatttc cgcaaaaagc aacacgtccg
     9841 cagtattcag tcatgagcct gaaaaagaca gaagagttag gatttgtcat accaacttgg
     9901 caagaagcac ttgcgcaaat gctggaagct gccaaaaaaa tgaataagta atttcctttt
     9961 atcaaataga atttggagca tgatatggaa aaacaaacaa gaagtgcacg acgaaaagaa
    10021 aagccaaaag cgaaccaggc agattcgaat ttggtgcttg acctgtttct aaaactccgc
    10081 tatcttattg gcgttttagt catcgtggtc atcgttactt ttaatttaaa cggaagttca
    10141 cttggtgttt gggataaata tgtgtcgcaa agagacgatg ggaaaaaaac tgatgtgatt
    10201 tttggacaga atcgggaagt gcggtcagac gaatggctgg tgcagacacc tttttacctc
    10261 tcacaagctg aagaggactt tccgttggtg aacgaggatt attcattaaa cggacaaaac
    10321 atgatcattg cgtataattc tcctgtaaag gatattacgg ttatcggaaa accattcaac
    10381 tggggattct ttttcctcgg aagagatcga ggactttcct tttattgggc gatgaaatta
    10441 gtcgtcatgg tcttgcttgg attcgaagta ctgatgatat taacgaagag aaaaaaagct
    10501 ctatcgctaa tcggtgcatt tgcgctgaca ttttctccag cagtccagtg gtggttcatg
    10561 caacatgtgg gcgatttgat tttctttact ttgggactga tgactgcttt ttatcattat
    10621 ttctacaatc atgataaaaa atggctacga acgttgatga tgcttttggt ggttattttc
    10681 ggtattgggt ttattttagt gatttaccca gcccatcaag tgatgctggc gtacttgctg
    10741 attttttatt ttgttggcct gcttatttac tatagcaaga aagtttcatg ggatctgttg
    10801 gatgtagtgt tgattggagg ggcagtttta tttattggcg gagtcatggt tcatttctgg
    10861 ctaacgtcaa aagacgcatt gttagcttct ttgaatacct tatatccagg aaaacgggta
    10921 agtactggag gaaagtggac gattggcgaa tttttttctt tccttacaaa ttggaaaatt
    10981 ccttttgaag atatcaacta ttcgaataac tctgaagtgg ccctgttcta tcactttttt
    11041 ccaactgtat tcctagcaag tccatttgtg ttatttggca aaaaagatag cgaacaaaag
    11101 ttactgggac gtattttgat gattttttgt ctgttttcta tcttttggat taccgttggg
    11161 ttgccaaaat ggctagcaga aatcactctg ctgtcttatg ttcctccatt aagagccatc
    11221 cttactttta gttttgcggc ttgtttatta tcgatctggt ttatcgctta tatttggaga
    11281 gaagatgtta ttcctatttg gtataaattc attttgttgg cagtaaatgc atggtcttat
    11341 ttctatgcga ttacgcattc gaaaatggat aattattttt cggattttga aaccatcgca
    11401 gttgctgtgt tgggaacagt gattttagct tttgcattat ttggctggag acgcttgttt
    11461 tacctcgctt ttgccgcctt agttatcgta tctggctttt tcgtcaatcc agtcgtagaa
    11521 ggtacaggag cgatttttga aaaaacactg gcaaaagaaa tccaaaaaat cgatcaacaa
    11581 gatcctggta aagtttggtt gtctgaagat gaattatata acttcacccc aacattggga
    11641 gtgaaatcct tcaatacagt acgcttttat ccagatatag ctgcatggaa gaaaatcgat
    11701 ccgaaagaag aatacgagaa gtattataat cggtatgctc atacaagagc ttttatcgct
    11761 aaggaagata caaagttcat tttagatcgt ccagatatgt tttcggtcac gttgaatttt
    11821 gaagacgcag aaaaattagg gatcgactat gtgatcagta aacgaccatt aactgattac
    11881 aaccaattat atgaagcgca gttcacgcag ctatatggac cggataaaga cggttatatg
    11941 atttttaaag tagaatatcc ggattatcca gatgtaccac aaacacaaac tcaggaaaat
    12001 cagctagtcg tacagtaata ggctagctga gaataatcct gaaatgttag tagaaaggag
    12061 agtggagata attcaagcaa tcgtacaaaa atttgtcaac aaaatgagtg tcggtttctt
    12121 gcttttgtta ctgacgctag tcttttttgt ttggacagca gggttaggtt ttccagcaac
    12181 tttgtttata tataacaata gttcattact tatcgctttt agtgtggcta ttttgctcat
    12241 tttaaatgtt tataaagcaa aaggcgtcga ttttctttat ctaggtgttg cgcttgccct
    12301 tttcattttc ttttcttact ttcgggaatt aagaaatgag tctttatttg gagacttact
    12361 gtttcctttg attattttat tttgtttagt aattaaatgg atcgagtgga caaaatggga
    12421 tcgcggtatt tatctgattg tcttttcggt cttcctcgga atcacgttat atcgtgtatt
    12481 tacagagatc caagtaccag aaggacaaag catctgggct ccaggcaatt cgctttctga
    12541 tatttggatc aatacgaata taatcggaag ttctttgatg actcttgctt tattgatcag
    12601 tggatttgcc agttcttttg aacgatggta tgtacgaatc atcggtgcag tagcagttgt
    12661 tgcagctttt ctcgggattt gggtctgcca atctagaggt gcattagtcg cgttgattgt
    12721 ttttgcgata ttggatcttt tacctaaatc gttgatgcgt gtcattcgtg cgccatttat
    12781 tgcttacacg gttacgattc ttttagcttt gccgatttct tatctggcgg ctgtctctga
    12841 aaaagtcaat ttgtttaccg gtcgagaaga tatttggcat aaattctatc agacgctagg
    12901 agaaaaatct gaacaaattt tactaggaat gaaaacattt atcttccaac gaggaaacca
    12961 atttttagga aaccacaata gttataattc tattttgaat atctatggat tgataggatt
    13021 tgggattgct gctttgctgc ttatcctttt tattggtcgc ttaacgttga aagcagattt
    13081 atccaacggg cagatgactt ttatctgggc cttttttgcg gtgatgatgc agtcatttat
    13141 ggaggataca ttgacttcat acccatgggt tccgattatt tatatcctgt tggctatggc
    13201 cgttcatcga tatgatgaac cagaagttgc ggaggaattc tatgttatgg aagaggcata
    13261 tgacgatatg acttatgatg atacatctta tgaggaacaa ccagatagcg ctcattcttc
    13321 caggatccaa cgctatcatt gataggcaca aaatacgaga gaggctgtga caaccgtcgc
    13381 agcctttttt ggtttattgc aattgtctag catcttctgt aaaatagaaa cgttagagaa
    13441 aatcttgtat catagaaaat taagaaagaa ataagaacgc agctcggtac caaaaatatg
    13501 gtaaaatggc acttgactgt aattcactga aaatcgcttg gaggaacaca aatgtttaaa
    13561 gatttgtatt tatttatgaa ggacatttat cagaacagaa aattattgct acagttttcg
    13621 atcaatgact tcaaatcaag atatgcagga tcgtttttag gaatcttatg ggcgtttatc
    13681 aatccgctat ttactgtatt gatttattgg ctggtatttg gtgttggact gaaagcacaa
    13741 atgatcgatg caaaataccc atttatcgta tatttagtta ccgggatgat tccctggttc
    13801 ttcttctcag atgcatttgc atcaactacg gttgtttttc gggaatatac ttatttagta
    13861 aagaaagtcg tattcaatat tcgtatcttg cccacgacga aaatcctatc caatctgtac
    13921 acccacttat tcttcattct gattggcata gctgtcgcgc ttataaatgg tatatatcct
    13981 tcagcaatgt ctttacagct gatttattat ttattttgca tgtgtgcttt cttgacagga
    14041 ttgacttggc tgacggcatc gatccaacca tttttacctg atatcatgca attaattacg
    14101 atcgtgctgc agttgatcat gtggacatta ccgatattat ggagccctaa tcagtttgat
    14161 tcaggtcttg taagcatatt gaaattaaat ccgctgtact atgttgttca aggttatcgt
    14221 gagtcatttt taagtgaagc ttggttctgg gagcatggaa catatacttt gtatttctgg
    14281 gttttcacgt tagtaatgtt cgtaatcggc tctgcagtgt tccgtagatt gaaaccacat
    14341 ttttcagatg tgctgtaagg agaatagcta tgacagaata tgcaattaga ctaaaagata
    14401 tcacaaaatc ttataatatg tacgcaaaac cttcggatcg atttcgtgaa gccctcaatc
    14461 cttttaagaa atcctatcat gatgtatttt atgcgttgaa aaacgtgaat gtagaaataa
    14521 aaaaaggtga gatgatcggt ttcgtgggag aaaacggatc gggaaaatct acaatgttga
    14581 aaatcattac gggagtactg acaccaacat ccggcacgat ggaaatcgaa ggaaaaatct
    14641 cagctttgct agaactagga tcaggattca atcctgagta ttctggctat gaaaatatct
    14701 atttaaatgg aatggttcta ggattttcaa gagaagaagt cgatgaaatg gtcgatgata
    14761 tcattgaatt tgctgacatc ggagaccata tttatcaacc tgtaaaaact tattcaagcg
    14821 ggatgttcgt tcgtctagct tttgctgtag caatcaatgt gaatcccgat attttgattg
    14881 tggatgaagc attggcagta ggcgatcttg aatttcaact aaaatgtatg gaaaaattta
    14941 cagaaatcaa gaactcggga aagacgattt tattcgtttc tcatgatatc agttcgattc
    15001 gtcgtttttg tgatcgttcc tattggttga aaaacggaga agtcgtcgaa tatggcgata
    15061 cgatggaagt aacgacgaat tatgaaaact ttttaaagaa aaaatcagtt aaaacagtgg
    15121 atcggaataa aaaccaagta gaacggttcg ccgctccaga tatcgtcgac gtgacgaaag
    15181 cggaattgtt ggataaagac aaaaatccgg tggatatgct ggaacaagga gaaaaactat
    15241 acgttaaagt aacttatgaa gtaaaagatg atacaatcaa aaatccggtt ttaggaattg
    15301 cgctacgaac agtcgacaat ttttatgtat gcggacttaa tactctacta gatggtatca
    15361 agattccttg gaaaaaagga gagaatatct tttatctgga gtatgaaaag ttaggtttgt
    15421 tagctggtga atattatttt gacgttgcgg tctttgaaga aaatgcaacg gttcctttgg
    15481 tatataagac aaagtacatg aacttgtttg tcagcggttc ttatatcgga gaaggcatcg
    15541 tggtcttaga ccataaatgg gaagaaggga ctcatagcaa tgaaatatga ttttgaaatg
    15601 gacctagatg aacaaagcag tgtgggaaaa attgccgcac agatcaaacc aggaagtaaa
    15661 gttttagagt ttggtcccgg aaacggccga ttaacgaaac atttaatcgg agcaaaacaa
    15721 tgtgaagtga gcattgttga gttagataag gaattgttcg attttgtcag cgaatttgct
    15781 caagatggat tttatggtga tatcgaaagt tttgagtggg caaactatta tgctggacag
    15841 acatttgatt acgtcttgtt tgcggatgtt ttagaacatt tggtagatcc tggaaaaaca
    15901 ttgaagaaag tcagagaatt tttgaatgaa gaaggagaga tcctgattac attccctaac
    15961 ttggcgcata attctgtcat gatcgatttg ttcaataacc aattgccgtg ggcttcttat
    16021 ggtctcctag atgaaaccca taattctttt tatactcatg atggcttcca aaaagttttt
    16081 gaaaaagcgg gattattcat taatattgaa gattatttgt acttagctgt aggtgataca
    16141 gaattaaaat caacttatga agaattgccg gaagctgtac gctatgattt caaaatgcga
    16201 ccatttggtg aagtctacca atactttttc tcattgatga aacatccagt agcacaaagt
    16261 tccattgcag agccacaaaa ttctaattat gtaaaagtgt tagaagtaac ccagcaaacg
    16321 aaacaagatg aaacaatcca acaaatacca ttcaataatt tcacagggga aaatgagaca
    16381 ctaagtttcc ccgtatcaga aacaacagaa agaatggtgt ttcgcttcgc gcaacaacct
    16441 agctttatcg aattcagcgc agaagctgcc ggagaaaaac taacatttat cgattcgaat
    16501 gctgtagtca aaacagtaaa tgattgttat ttgtttgatg ggaaagaatt accagagttc
    16561 gttctaacgg atatttctgg gaaagaagtg actatccatt gtcactatcg ctttatcggg
    16621 gaattgacac caacaatgaa agaattgttg gaaacgattc gtcccatggc tgaagtcaca
    16681 aagcagcttt ctgagaaaaa tgacgaatta gaaagagaaa atcatcatct tcttgaggaa
    16741 aatacaagac tagaccatac gttaaaaaca accacaaatc gctattgcac attgttggaa
    16801 agtgatgaat ggacaataaa acatagacta ggacgacgta agaaagaaac ttcgaaaaaa
    16861 atccaagaaa aagaactttc tatatgtatt gacgagaaaa tctgggatgc agaaacaaaa
    16921 atattaaaaa tcatcggatg gggaatcgct aattcggatc gccagccctt gtcctataag
    16981 ttatcagctg accaatcgcc atttttcgaa gcaattcctg tttcacgaga agaagtcaat
    17041 caagcagaac agctcgcaaa aggaacagaa gcgggatttg agttacgaat cctttgcgag
    17101 caagaacgtt cattcttagt ggaagcagta gctcaaaatg gccaatcatg gatcattgaa
    17161 atgtaaataa tgattaactt ataaagataa ggagtaaacg aatcgtgcaa aaaaaagaaa
    17221 ttgccgtatt tatcgatcaa atcactcgtg aacgggccac tggcgatttg cttattgtgg
    17281 gctgggcaat tgatgaagtg accaaagaaa tccctacgat aaaggtagaa aaagaaaatg
    17341 tgattgctga agcaacacat gtcgtaagat tggatatcaa tcatttatat aatcttgatg
    17401 ttaagaccca aagcggtttt aaggtacgtt tatcagggaa aatgagagga aaagccatct
    17461 tagacttcca aacagcgaga catcaaaatg gcatagctgt gaaattaaac ggtaaatacc
    17521 cttatgatga cggcattgaa tcttcatggg aaagaaaaaa aagattactg aaaaaaggga
    17581 taaattatgc aaggactcat ggcgtaaaaa aagcgatccg tcgggtcaaa ttggaattga
    17641 agccaggatc gatcgactat gcagagtgga tcagtcgtca tgagaaacca gatttgaaag
    17701 agcaaaggaa agaagcacaa ggatttgcgt accgtccatt gatttccata cttatgcctg
    17761 tctataacgt tgaaatcaaa tggctcgaaa aatgcattga ttcggtactg gatcaaacgt
    17821 atgatcattg ggaactatgt atcagtgatg atgcttctac tgatccagct atccgaaagt
    17881 gtctggaatc ctatcaagca aaagatgata gaatcaaagt cgttttccga aaagaaaatg
    17941 gacacatcag tctggcaact aattctgcat tggaaatagc agaaggagaa tttatagcac
    18001 tcttagataa tgatgatgaa ttaccgccat ttgcattata tgaagtggca aaagtgctaa
    18061 acgtacatcc agaactggat gtgatctaca gtgacgaaga taaaatcgat gcagatggca
    18121 atcgctttga tccgcatttc aaagcagact ggtcgcctga tacattgatg ggaaataatt
    18181 atatctctca cttaggcgta tatcgaacaa gcattgttaa agaacttggc ggtttccgta
    18241 aaggctatga aggttctcaa gattatgatt tggtccttcg tgtgacagaa caaatccctg
    18301 cagatcatat ttaccacatt gaccgagtct tgtatcattg gcggacgatc ccaggatcaa
    18361 ctgcaagtaa tggcgaagcc aaaagttata tctatgattc cggagtgaaa gcattgacag
    18421 atgccctgtc tagaagaaac atcaaaggaa gcgtatgtcc tggcagaatt tctggatttt
    18481 atgagattgc ttatgacgtc ttgcaagagg atttggtcag tgtgatcatt ccaacgaaga
    18541 atggctatga agatctaaaa acttgtgtgg attcgatcat cgaaaaaacg tcttattcaa
    18601 attatgaaat cattattgcg gataacggaa gtacagatcc aaaaatgcaa gaattatttg
    18661 cagaatacaa gcatcagctg aaagaccgct ttatcgtaga attgattgac attccattca
    18721 attattctcg aattaacaat ttagcagcag aaaaagcaaa cggcaaatac tttttattct
    18781 tgaataacga tacagaagtg attgagccag attggatgac ggtgatggtt tcttatgcac
    18841 agtttgatcg aatcggctgt gtaggagcaa aactgtttta tccagatgat acaacgcagc
    18901 atgcaggagt attattagga atcggtggtg ttgcagggca tgcattgaat aactatgatc
    18961 gaacacattg tggttatttc ggccgattgg tcattgacgt caattactta gcagtcactg
    19021 cagcttgtat gatggtcaag gcagctgact tcaatgctgt taacgggttt gatgaaacat
    19081 tagaagtagc attcaacgat gttgacttgt gcttgaaagt ttatgaactg ggtcgttaca
    19141 atgtctatgc acatcaagca gaattgtacc atttcgaatc taaatcaaga ggttatgaag
    19201 atactccaga aaaacaaaga cgttttgctg gtgaaatcaa aaaaatgcaa gataaatggc
    19261 cagcatatat tgcgcatgat ccattttaca atgataattt aacaaaagaa ggaatcggcg
    19321 acttttcgtt gagaccagat taaactataa taaaaagctg ttatgttgtg attcgctcgc
    19381 acataacggc tttttatagt tttttgtcaa aaaaaggcag aaggtgccga ctcaaaaaaa
    19441 taagtcgagg ttgggacaga agtgtttaac tccgagaaat aagaagaaat tcacgaaaat
    19501 tgcttttcaa atttttgtga atttcggctt atttaagaag aagttgcttc tgctcccacc
    19561 gtttattcgt ttttaaagaa tgagacaaaa gtgtttctta cttttgtccc acgctcttat
    19621 tcatgctcag agcgccaata gatacaaaat catagccaaa gtttcacgaa ccctagctgt
    19681 caaagaatcg atattttatt ttaatatagg ctattttaaa ataaatggtt taaggtattc
    19741 ctctacaaaa gccactctat caattatcat gggtttaaaa taagaagtga tggagataac
    19801 cagattgttc ttagcgtcaa tataaagaac atttccacta ttaccaattg ctgaatatat
    19861 ttcgttctca gaatctaata cccaccataa atagccatat ctcatatttt gtaagtcttc
    19921 taaagcactg gttctaggtt tgaacatctc gtttatccac atgggtggta cgatttgttt
    19981 tcctttatac atccctttat ttaggcataa tacaccaatt tttgccagat cacttgccga
    20041 taaacacaaa ccatatcctg ccgtcccgat atttagtgga tcacaaaacc agacattggt
    20101 tttaggagac ttatccattg taaactgctt atgttcttca gctgtttcag cataataatt
    20161 gacatggttt ggtatcccta taggatcaaa tagatactta ttggcaaaat caacagttgt
    20221 tagcttactt gtctgataca acaagccagt taatatgtgt aaacagacag tttgatagtt
    20281 gaattcgccg gttatacctt ttcttcctcc caataaatct agtgatgttt ttgtccaatc
    20341 ttcacttgaa cagacttttg tccatggatc gcctttacat ttgtagggtg ctttcattgt
    20401 tagcaagtgc ttgattgtaa tagcgtaaat agttttctcc ccgcgtttca ctttatactc
    20461 tggaaaataa tctaatactt tatcatcgat acttttgatt aatccttgct ctaaagcaat
    20521 gccaatcagc aaagatacaa tacttttcgt tgctgacatg atatgacaag tatcgtcttt
    20581 tttataacca ttccattcat ctgtataaac ttctacccca tccttatatg cgacaatttg
    20641 acatatattt ggttgtcgaa aaccaataaa atcatgcaac tcttgtttat tcataagata
    20701 ttacctcact ttcttctata agcataatgt cattaaaaat cgatttcaat tttttcgatt
    20761 cttcacgtaa tacaggtatt cttatggact agacagcgct ttgggaagat ggattctctg
    20821 aaaaatataa aggttcactt tatgagtgga taaaaaaagc agcaaatact tcgacttctt
    20881 taatttacca acattagtga aaatcgattc atctggagat ttgtaattta gagtccttgt
    20941 cttgattaga ggtgtataaa gctttttatt agacattttt aaattccatt acaatttgct
    21001 tataaactag gtttttaaag gtgactatgg taagataata gagatattat tttgtgatta
    21061 ggagtgtata tatgaataaa aatggagaat ggagtgctgc acgacggata ttcattatat
    21121 taatggatgt tattgtatac aatgcagcaa tatatagtag tttcttactg aagtttcgtg
    21181 gagagatccc attacgaaat ttagaaactt tccaacactc agcaattatt atttcagtga
    21241 tttttattgc gttgaacatt ttgttgggtg catatgtttt ttataatcga atgatcagtg
    21301 acatcgtgtt tgtcacagtc atcggtcagg tattgatgac actagggatc atggtagtga
    21361 cttttgcggg ccgctggttt gcttttccac gtcttgttat cttactttca tttgttctcg
    21421 gtacgctttt cttaagtatc tatcgtattc tcgtatataa actttattta cgcgtaagtc
    21481 gagataaaaa ggtcgtcatt attgggttag aaaaggatgt cgcaccagca atccaaaatt
    21541 ttggttcaaa gaaaaacaac aaacataaag tcgaagcagt cattcttgat aactattatg
    21601 caaacatcaa aaatatgatt aaagacatcg atattgtcta tcttgcttct catatcgaag
    21661 aaactgaaaa aatcaaaatc tatcaattag ttactaaaaa tgaaaaaaaa ttgtttttga
    21721 atacaacatt tgaaaacttg acattgatca atccaaatat tatgaatttc gaagatgaaa
    21781 gtattattga agcatctgga tttagaatcc aacctgaata tgaactattc aaacgtttgt
    21841 ttgatatcat cgtttcactt gttttattag ttattgcttc accatttatg ttattcacag
    21901 caattttagt caaagtgaca tcaccgggac caatcatcta taaacaagtg cggatcacaa
    21961 aaaatcaaaa ggaattttca atctataaat tccgctcgat gaccgccaca gccgaagcaa
    22021 aatctggacc agttttagct aagagcaatg atgcacgagt aacgcctgta ggtaaattta
    22081 ttcgagctgt ccgctttgat gaattaccac aaatcttcaa tgtgctgaaa ggcgatatgt
    22141 cgatcgtagg accacgtcct gaacgtcctt tcttcgtcga tcagttcaat gcagaaaacc
    22201 cttattacta cttacggcat aatgttcgtg ctggtatcac tgggtatgca caagtctatg
    22261 gaaaatatgt ctctgattac aacagtaaat tacgttttga tttactttat atcaaaaaat
    22321 attcattgat gcttgattta aagatcttgc tgcaaaccat caagatccta tttgataaaa
    22381 tgtcctctca aggacttgaa gaagacgaaa atgtgatctc attggcagaa attgcttttc
    22441 cgaatgaaaa aatctttcgc tagttgggag gcgtaaaaat gaacaatccg aaattcagca
    22501 taatcgtacc agtatacaat gcagaagcaa ctattggtcg aacgattgat attctaaaag
    22561 aattggatta tgaagagtac gaagtcgttt tagtaaatga tggatcaaca gatcaaacac
    22621 aggaaatcat tcaagaactg attgaaaatg atgaacgttt tgaattgatt actacgacca
    22681 atcaagggcc cggattagca agaaacgaag gaataagaca gtcaaaagga gaatatctct
    22741 tattcttcga tgcagatgac acgccagtaa aaacgatctt gtcagattat gatcatttgc
    22801 tagaaaagag tccaaaagcg gatcttgttg ttagttcgtt tgtttttcgt acaatggacg
    22861 agggaagaat cgtttccgaa aaagaaaact tagttacaga atgtcactat ctaactcacg
    22921 aagagtttat aaaagacatg tatcagttaa tgaatgaaca gttgatgtat gttgtatgga
    22981 acaaatgcta tcgtagcgat attctgaaaa ataaccaaat tctatttaaa acttataata
    23041 gttgtgagga tcgaatattt aacttacatt attatgaata ctgtcatcaa gtgatcatga
    23101 acccaaaagt agaatatatt tatgaatttg aaggtgggaa ggggatcact aatcaatacc
    23161 gacctaacaa gttcgaaaca tttaaagaat tctattcatt agcaaatact gtaacagacg
    23221 atattaataa agacggtatg gcggcgcttc ttttaaaagg gacaacttca gttatttttt
    23281 ctatttatag tacctctgca agaacttcaa aagagaagaa agacgaagca aagcagatat
    23341 tgagtgatcc agtgatccga gaagccaagc aaattgctaa gacggattct tcagcaaaaa
    23401 aaataacaaa gttgctttac aatatgccag ctccactatt tttatctgct gtaaaagttg
    23461 gaagcttcgt tgaagtgaaa atgccagggt taatggctgc tttgaagcga gtatattagt
    23521 taatggagga aaatataatg aaaagaattt tgcattttca gggacgaatg ggtttaggtg
    23581 gagcagagtc tttcatgatg aatttatatc gtaaaattga tcgtacaaac tatcaatttg
    23641 attttttgat ttatgaagat tatgcagatg ttcaagacta tcattcagag attgaaagat
    23701 taggaggccg tatttttgtt gtacctaatc ctaagaaaaa tatttttaaa tatttaatag
    23761 aagtgaataa gttactaaaa aaagaatctt tttctatagt tcacaatcag gtttattttg
    23821 gcgggggaat taatttatgg ttagccaaaa agaatggaat cagacagaga attgctcata
    23881 gccatgcaac tgaagatgga aaatctcaaa atattgtaat gaatgtattg cgtaaatttt
    23941 taaccaaatt gttgttacaa aatgcaacag actaccttgc cgttagtcaa gaagctggtg
    24001 aaagtctgtt tcaaaaccac ccctttgaga tagttcataa tggtattgat ttagagcttt
    24061 atagtaaaaa ttcagaagct aaggttaata agagaaaaga attggatatc tcaatgagta
    24121 cttttgttgt gggaaacatt ggacgattag agaaacaaaa aaatcaatct tatttgttag
    24181 agattttttt agaaatacta aaaatgaatt ctgattctta cttgatttta gtaggtgaag
    24241 ggtcacttag aaataaactg aaagccaaag cagtagaatt ggatatagag aaaagagtaa
    24301 aatttttagg agaaagaaac gatattcccg agttattatc tgtgatggat gtttttgtaa
    24361 tgccttctct ttatgaaggt ctgccaatgg ttggattaga agcacaagca gcaaaattaa
    24421 aattagtctt agcagatact atttccaaag atacaaagtt aacaaataat gtggattttg
    24481 tatcattaga tgaaacacca caagaatggg caaaaaaagt aataaaagag ccgtatgcta
    24541 ataaaataac acaagaacta aagagttatg atgtttcgta cactactgaa caaatggaga
    24601 gtatatatag tagagatcat taaaaatgtt caagatattt taggagtgat tatttttgaa
    24661 aatatgttat ttgatattgg catacaatga tattggcaac ttaaagagat tggtcaatcg
    24721 attgaacgaa aatgcagttt ttattattca tatagataaa aaaactgata tagaaccatt
    24781 tattgaagca tttaaatcat atgataatgt tgaattttta tgtaataaaa accgtgttaa
    24841 aatttattgg ggtggttttt ccattgtaca agcagaaatc aatttagtaa agagagcatt
    24901 acaaaatgag aaatatttaa aatatgtatt attatctggt gctgattatc caatcaaaga
    24961 taatgagtat atttataatt attttaaaaa gaatagttca gtggagttta ttcgtggaat
    25021 agatctagat caaattaaac ataaagaatt ttattataaa catatagatg tatatcaaaa
    25081 acatgattat cctagaatta ataggaataa cacaactgca tttaaaattt ttagagctat
    25141 aattaatcgt tgtctgagga tgattaaact tcccccaaaa attagacacc ataaatttga
    25201 tttgtatcat ggttctcaat ggtgggcttt gtcgaaagaa tgcctaacag aattaataca
    25261 aatgtatgaa caaaatcaac aagactacct gaattttaaa ataggtatgt ttgccccaga
    25321 tgaaaaattt tttcatacac ttttttttaa ttcctcgttc aaaaataaaa atgttattgg
    25381 aggaccagat ttaccacttg aattgaaaaa tattgaagaa actactttac aaacttcgaa
    25441 attagcaaat attcatatta ttgatccttc catgaacaaa tggtttgatg aaagggatat
    25501 agatcaaata aaagaaagtg aaaaattatt tgtaagaaaa gttaaatcgg attactctga
    25561 taaactatta aatagaattg ataaagaaat tttgaaagtt ggaaatatag atgaatagaa
    25621 tagtacctgt tttagagaag agtttattaa gtcgagatgc gtttcgagta ataaatttaa
    25681 tcatttgtct gctttatttt atgcctagta cttttaatgt aactaatatc ccgatgaaaa
    25741 tagcttttgc ttggggtgga attatagttt tgtatgaggt ttttataaag aaaaattttt
    25801 ttaaaatgcg tttttcttgg ctactgattg gagcaatgat tagttttatc ttaactataa
    25861 tcattaacag agaaaatttt ttaattccat ctatttataa ttttggatat ttgctgatta
    25921 ctttgatagt aatttttcct gcagactttt cacaaagtga agaggaaaaa aagaaaaaaa
    25981 tggtgtattt taataatgtt ttcattatca taattttttt agctgcgcta atatctatct
    26041 atcaatttat ttttttgatt tcttatcatg tcccaacagg aacgccagga ttacttgcaa
    26101 gacaaggttt tattgaacat cggttatttg gtgtctatac aagtccaaat gttggagcta
    26161 tgtttggata tacttctatt attttaagtt taattagtgt attaatttca aaaataacaa
    26221 aaacgattcg tgttttttat atgatgaatt ttatcgtaca aatattttat attacacttt
    26281 cttcgtctag aggtgcccag gtagtaattt gttctttttt agtattattt cttttgttgt
    26341 ttgccaattc aaaatttaga aagagcatta gagaagtact acctgtaaaa atcaaatgga
    26401 tggtaagcat attattagtt ctattggtat atttttcttt tggtactaat tatgctaagg
    26461 attttttagc aacaattcct gtatcgattg atagaaaagt agaagttata gagtcaaatg
    26521 aatcagataa aactccactt ccagaaaaag aagtaatatt acagcattct agtgataact
    26581 ccgaaatttc agctggtcgt tttacgattt ggaaagctgc gcttaaagtt ataagaccaa
    26641 ctttgttatt tggttatgga gagaccgatt tctatgggaa tagcgatgca aaatttttga
    26701 aaaaagtaga tcttgatact acagatgtga atgaactaaa aagagcacat ggaaacatgc
    26761 ataatggatt tcttcaagta cttgtatcaa gtggtataat tgcttttata tgtatctatg
    26821 ctttctatgt gttaaatatc tttagtttac tcaaaacatt ttttagaagt aaagtgaatt
    26881 atgcgtttct tggtattgtt ttaattttta tactatctat ttttatagat gaaatggtgg
    26941 aggctcatgt acttttcaat aagcgcgatg tcatttcaat tgttttctgg tattatttgg
    27001 gaagcatttc ttacttgtat ttaaaaaagg agaattaata tgaagacagc tttcattgct
    27061 tggac
//
LOCUS       DAIGSZ010000039        26768 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.039, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000039 DAIGSZ010000000
VERSION     DAIGSZ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.039"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(26..1957)
                     /locus_tag="NOB31_001713"
     CDS             complement(26..1957)
                     /locus_tag="NOB31_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0973922.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="NOB31_001714"
     CDS             complement(1975..2889)
                     /gene="pfkB"
                     /locus_tag="NOB31_001714"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCI0973923.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2886..3638)
                     /locus_tag="NOB31_001715"
     CDS             complement(2886..3638)
                     /locus_tag="NOB31_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0973924.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3798..4007)
                     /locus_tag="NOB31_001716"
     CDS             complement(3798..4007)
                     /locus_tag="NOB31_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973925.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4018..5345)
                     /locus_tag="NOB31_001717"
                     /pseudo
     CDS             complement(4018..5345)
                     /locus_tag="NOB31_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5481..5636
                     /locus_tag="NOB31_001718"
     CDS             5481..5636
                     /locus_tag="NOB31_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973926.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(5710..6297)
                     /locus_tag="NOB31_001719"
     CDS             complement(5710..6297)
                     /locus_tag="NOB31_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HCI0973927.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6380..7630)
                     /gene="clpX"
                     /locus_tag="NOB31_001720"
     CDS             complement(6380..7630)
                     /gene="clpX"
                     /locus_tag="NOB31_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HCI0973928.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7877..9166)
                     /locus_tag="NOB31_001721"
     CDS             complement(7877..9166)
                     /locus_tag="NOB31_001721"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HCI0973929.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9320..10252)
                     /locus_tag="NOB31_001722"
     CDS             complement(9320..10252)
                     /locus_tag="NOB31_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973930.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10409..11068)
                     /locus_tag="NOB31_001723"
     CDS             complement(10409..11068)
                     /locus_tag="NOB31_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCI0973931.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11071..12096)
                     /gene="sppA"
                     /locus_tag="NOB31_001724"
     CDS             complement(11071..12096)
                     /gene="sppA"
                     /locus_tag="NOB31_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HCI0973932.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12109..12399)
                     /locus_tag="NOB31_001725"
     CDS             complement(12109..12399)
                     /locus_tag="NOB31_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973933.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12808..14613
                     /gene="glmS"
                     /locus_tag="NOB31_001726"
     CDS             12808..14613
                     /gene="glmS"
                     /locus_tag="NOB31_001726"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HCI0973934.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14685..16040)
                     /locus_tag="NOB31_001727"
     CDS             complement(14685..16040)
                     /locus_tag="NOB31_001727"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HCI0973935.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16064..17233)
                     /locus_tag="NOB31_001728"
     CDS             complement(16064..17233)
                     /locus_tag="NOB31_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973936.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17230..18117)
                     /locus_tag="NOB31_001729"
     CDS             complement(17230..18117)
                     /locus_tag="NOB31_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HCI0973937.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18306..21998)
                     /gene="nifJ"
                     /locus_tag="NOB31_001730"
     CDS             complement(18306..21998)
                     /gene="nifJ"
                     /locus_tag="NOB31_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HCI0973938.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22197..22718
                     /locus_tag="NOB31_001731"
     CDS             22197..22718
                     /locus_tag="NOB31_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCI0973939.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(23417..23974)
                     /locus_tag="NOB31_001732"
     CDS             complement(23417..23974)
                     /locus_tag="NOB31_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973940.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(24153..24764)
                     /locus_tag="NOB31_001733"
     CDS             complement(24153..24764)
                     /locus_tag="NOB31_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973941.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(24877..25134)
                     /locus_tag="NOB31_001734"
     CDS             complement(24877..25134)
                     /locus_tag="NOB31_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973942.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(25731..26009)
                     /locus_tag="NOB31_001735"
     CDS             complement(25731..26009)
                     /locus_tag="NOB31_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973943.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(26043..26294)
                     /locus_tag="NOB31_001736"
     CDS             complement(26043..26294)
                     /locus_tag="NOB31_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973944.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         7559 a         5767 c         4584 g         8858 t
ORIGIN      
        1 aaacccagcc tcttcttttt tatttctatg cttctgctac tgcaggagct tttctcaata
       61 aaccataaat cacaccagat acgactgctc cgatagcaat aaacaccaaa tacatgaccg
      121 ggtgactcag taagaataca acgaaaatcc cgccgtgagg agccagtaat ttgattccga
      181 aagctccgac taatccgcca gttaaagcag aaccaataat aaaacttgga atggcacgaa
      241 tcgggtcagc tgctgcaaat ggaatcgatc cttccgtgac aaacgatagt cccatcacga
      301 tgttcgtcaa accagcatct tgatctgttt tgctgaattt attcttaaac aaacgtgtag
      361 caacgaaaat tgccaatgga ggtaccattc ctccagccat aacagaagcc atcacgacac
      421 ttccgccagt tgcaacagtc gtagctaaag ttgctgtacc aaacacataa gcggctttgt
      481 tgattggacc gcctaaatct gccgccatca ttccagctaa taatgcacca agtaaagcag
      541 cattcgaacc actcatactt gtcaagaaac cgttcaatgc atcattgatt gctttcatag
      601 ggacattgac cagcaacatc aagaaaccag taatcagtaa gccaaacact ggataaaaga
      661 ggatcgtttt aattccatcc aatgattttg gtaagttctt gaataattta cgtaaaaata
      721 cgatgacata accagctaag aatccaccaa tcagtgcacc taagaatcct gcaccgcctg
      781 tattagctaa tgcaccagca gcaaatccaa cgatcaaacc agggcggtca ccgatacttg
      841 aagcaataaa tcctgctaat accggcagca tgaaaccaaa tgcagcttgt ccgatttggt
      901 tgaaccagct agcagcttga ttgtaattcc ctagatttga taattgatca tgtggcacgc
      961 caataaattg gtcgatcatg aaagaaagcg caatagcgat tcctccacca ataacgaaag
     1021 gtaacatgtg tgatacgccg ttcatcaaat ctttgtaaat tctttgtccg atagtaccat
     1081 ccgcatttcc ttcttctgaa ctgctttctt ttccatcacc atggaatact ggtgcagtac
     1141 cactaagggc tagattgatc aactcttctg gtttacggat accatcactg acaggacgat
     1201 tgatcagttc ttttccgtca aagcgattca tctctacttt tttgtctgct gcaacgatta
     1261 caccttctgc acgggcgatg tcttcagcag tcaatcggtt tttgattcct tctgaaccgt
     1321 tcgtttcgac tttgatctcc acacccattt ctttcgcttt tttcttcaaa gcatcttctg
     1381 ccatgtaagt gtgagcgatc cctgttggac aagctgtaac ggcaacaacg aattttcttt
     1441 ctggatgagc agaagcttct gcagcttgtg tttcttgttc tgctttttct tctgcttctt
     1501 tttgctcttc agctgtttgg aacaagtctt ggacttcttc tggtgtattt gcttctttta
     1561 attttcctac gaaatctgca tcaatcagca atcgagatag tgctgctaat gcttgcaaat
     1621 gtgtgtcgtt tgcgccttct ggagctgcga tcatgaaaaa cagataagtt ggctgtccgt
     1681 ctaaggcttc ataatctact cctttttggc tttttgcgaa taaaactgtt gcttctttaa
     1741 ctgcactgtt tttcgcgtga ggcatggcga ttccatcacc aagacctgta gaagtttgtg
     1801 cttcgcgggc tagaattcct tctttatatg tttcgatatc ggaaatccgg ccggcatcaa
     1861 acattttttg gaccatttca tcgattgcgc cttttttatc agtcgcttgc aaatccatga
     1921 tcatcgcttc tttgaccatt aaatccttga tattcatgat tatcctcctt gaaactaatc
     1981 aatttttgtg atttcaactt ctggcagcaa ctcatcaatc aattcgcgag ctgccaagtc
     2041 atcagaaaaa gctgttgcgc ttccgcaagc aactccccat ttaaaggctt cgattggatc
     2101 tttcgtacgg ctgtaagccc caataaagcc agcaatcatt gaatcccctg cacctactga
     2161 atttttcaat gggcgaacta atacattcgt tttataagtt ccttgttccg tgaagagcaa
     2221 agcaccgtct ccagccattg agatcagcac attctgtgcc ccttcagcta gtaatttttt
     2281 cccatacgga atgatttctt ctacagattg gaaggttgtg ttgtaaagct cagctaattc
     2341 gtgattgttt ggtttgatca acaacggttt cttaacaagt gcatttttta ggtcatcacc
     2401 tgttgtatca atcacgaaat ctgcaccttt ttctcgaatg atatcaatca gttcttgata
     2461 aaatcctttt cgcaggctag ctggcgcgct tcctgacaat acgacgatat ctccttgtcc
     2521 tactgttcct aatgcttgct tcaactcatc gatttcttca tctgaaatag atgggcctaa
     2581 gccattgatc tcagtttcag tgtctgattt tagtttgata ttgattcttg tatcttcttt
     2641 tacggttgtg aacaaagact ggatttgttc tttttcaagc cacttcgaaa taaattcgcc
     2701 agtgaaccct cctaaaaacc ctagtgctgt agattgagaa tcgatccgtt tcaaaatacg
     2761 ggaaacattg atcccttttc ctccaggtaa cttgaagtct tccttcattc ggttcaaatc
     2821 gcctagtttt aacccatcta cgcgtacgat ataatcaatt gatggattaa gtgttactgt
     2881 gtaaatcatt gtattgcctc cttaattgtt gtcttttcac ggaattcatt aacgaattct
     2941 aatggacaac gctcggttat gatcgtggct gcttccaaag gtgcaacaga ggtgaaggac
     3001 aactggttga atttggtatg atcaatcaat acaaatgtct cttcggaatt tttcatggct
     3061 aaacgtttaa cagctgcctc ttctggatcc ggagtcgtga atccttgttc aagatgggca
     3121 ccgttcattc ccataaatgc tttattaaaa tgaaaatttt ttagttgttc tatcgcatta
     3181 gatcctaaaa cagcattagt tgccagcttt atcgttccac ctaaaataat ggtagcaagc
     3241 tccaaatcaa ctaaatttgc cgcatgttga acggaatttg tcactactgt gatctgtttt
     3301 ccttgcagaa aaggaatcat ttctaacgta gtagagccag cgtctaaata aatgacatct
     3361 tcgtcattaa tggtttcagc tgccgatttg gcgatttgct gtttttcgtg aacgtttttg
     3421 agtgattttt cactcatatt ctgctcaaaa ttcaataatt gctctttctt agctccgcca
     3481 tgaactcttt ctagaaaccc actattctcc agctcttgta aatcacgtct tatcgttgat
     3541 tcagaagcat tcaaaaggtt tacaagatct tgtgatttca cgattttctg ctgttcaagc
     3601 aagtctagga ttttttgtct gcgttcctct gtaagcattt tcacgatcac ctcaatacaa
     3661 ataatagcat attttttttc tactagcaat ataaatcagt caaaaacgtt cataaaaatt
     3721 ataaatcagt caaaaaaaaa ataaaaaacc agtcagaaag actggttttt tatttttttg
     3781 tctatcatca agccgtttta tcgtttttta ttttcgcttc ttgttttttt catataaaca
     3841 gaagcaggtt ttctttcctt atgaagaaga taataataaa gtcccatccc gccaaacatg
     3901 accaaaaaac cgatgactga tcgaatagga aaattaggaa caaaaaagag acagacggat
     3961 aataatgatg ccggaaccat tattcgataa tagagttgtt tatccatttt cttcacctca
     4021 tattttttgt aaagtaatca attgttctaa ttctcggtaa tctaaaaatt gcacacgcag
     4081 atgctgctca cctttcttga catcgaattg gatacttcgc cgctttttct ttattcgttt
     4141 gaaggtaaca tcagagagtc tatgtttgat ttcctttaac ggtaattctg acagggattc
     4201 tgaaggaaca tagattctta aggataaaag atactcttga tatttttcat ctgttacctc
     4261 tacttctaga tattccctaa tataataaca ataagcttcg attccattat ccaaagcaac
     4321 agtcggatcg ataactttat agcacatcat gcgtgatcga ttctcgtcaa cccaaggaaa
     4381 atacgcctga gcatttagtg ttccgcgaac acgcctttct ttataatctc cttgttggat
     4441 atcataactt tttgttacaa aaaatgaagc attcttttta ggaacaggtt gcatttgtgc
     4501 attctgatac tggacagatt ggatcgtatg gtcagtgtaa atgtattcaa cgaatggcgg
     4561 tttcaataaa ccgacaccat tgtcccaagc aagatgatca aacccaagct ggtccctaaa
     4621 ataggattga aacatttgat tgtttggctt ttgccagtta aaggggtctc gataaagctg
     4681 gatacatatg acttcgtttt ctaattcctt cactttttct acttgttgga tgtcgagaaa
     4741 aatcggttta gggatgattt gatgataata gcgactataa tacatttccc aacacgaagt
     4801 gaaacataaa ccttggtaaa aaagatcgta tcctggaaat tggttgcaat cgactactac
     4861 ttccccgttt tgttgtttca ttttaggtaa atgttcgatt tcatcctttt tctcaaacaa
     4921 tagccgttga gagatctgtt ttgtattgtg atagataaac tcgctataag ctcgcatata
     4981 ggcgaacacc ccatgagcaa tcattttttt ctgaatgaag tctcgaatca aaaattgctt
     5041 ttctttgaaa acagagatag acaatacatt ttttatcaat aattgattat cttccaagcg
     5101 aaaactacat tcgttctcgt catttcctac aactaaccaa ctttcgtctc ttaccgatgc
     5161 tagcattatt ttttcttgaa gctttcgaag atcatacgga tccgcttgtt gtgtgaaaga
     5221 gcggataaat gttggctgga tcaacagacg tgtcaaaata gcccaatcgc ttatttcctg
     5281 tttttttctt cttcatttaa gtctgtgagc tggatagtca tcaataattt atcttcgcca
     5341 atcattttct cacctctttc aaatcttttt ataatttaat tataaccaat gataaagaaa
     5401 aactaaaact ttatgtctta gaaaccaatt tggacgatta catgatagac taagtaaaaa
     5461 gaaacaaaga ggtgtttaca atggggttga aatttgaacg tacagataat ttagataaac
     5521 ttttcgaatc atttgctgtc gatccggaaa aaacagttgc accaaaagaa gagatcgatc
     5581 gatttctaaa accacagcca caaaatgaaa agaaaaaaga caagaaacaa aagtaagtta
     5641 agctcaaaaa aagacttacc agccaaactt ttatgaaaga gtttgactgg taagtctttt
     5701 ttattctttt tatgattcaa ttgcttgttc gattgctgcc cacgcttctt cttttccctg
     5761 ttttgtaacg gaagaaaaga gaataaacgt gtcattgcga tcaaaatcca acgctttttt
     5821 gatttcgctc tcatgcttgt tccatttacc acgagggatc ttatctgcct tagtggcaac
     5881 aacaattaca gggatatcat aatacttcaa aaattgatac atctggatat cttcttgaga
     5941 aggcttatga cgcaaatcta ctaaagaaac gaccgcacgt agctggtctc tagtcgttaa
     6001 atatgtctcg atcatctttc cccattttgc tcgctcagtt ttggatactt ttgcataccc
     6061 atatcccgga acatcgacaa aatgtaatgc gttctcgatc aaataaaaat tcaatgtctg
     6121 ggtctttcct ggcttaccgg aagtacgggc taaattcttt cgatcaatca atgtgttgat
     6181 aaaagaagat ttccctacat ttgatcgtcc tgccagagct atttctggca attgtgtatc
     6241 tggatattgt tttggtgcca ctgcacttat gataatttca gcttgatgga ctttcatggt
     6301 ctctctcctt aacaaggtga tgaataaagc aagcggctgt cgcaaaagcc aaaatgactt
     6361 ttacggcagc ctcttttcat caacccgctt ttttctctga atctttatag attactgttg
     6421 gctcaccaga caattcagct gcttcttttg tgataatcac tttttcgatg ttttcatttg
     6481 aagggatatc aaacatcaca tccatcatga tttcttcaat gatggaacga agtcctcgag
     6541 caccggtatt gcgttcgatt gcttttttcg caatggctct caacgcttca ggttcgaatt
     6601 caagttcggt attatctaga gaaagaagtt tttgatattg tttgactagc gcatttttcg
     6661 gctcagtcaa gatccgtacc agatcatctg ttgtcaattt ctctaaagct gccataacag
     6721 gtaatcgtcc gataaactca gggatcaatc cgaattttag taaatcttca ggaatgatat
     6781 gctgcatgac actttcgtct tcagaaagtt tttggttttg tgtaccaaat ccaatcgtct
     6841 tttcgcccat acgattcttc acaatcgttt cgatgccatc aaatgcacca cctacgatga
     6901 acaatatgtt cgtcgtatca atctgaataa attcttgatg tggatgttta cgtccgccct
     6961 gaggtggcac acttgcaaca gttccttcta gaattttcag caaggcttgt tggacacctt
     7021 cgccggaaac gtcacgagta atagatacat tttcgctttt acgcgcaatt ttatcgatct
     7081 catcaatata gatgatccct ttttctgcaa gttccacatt gtaatcagca gattgaagca
     7141 atttaagcaa aatgttttct acatcttccc ccacataacc agcttctgtc aaacttgtcg
     7201 catctgcgat tgcaaaaggt acattcaatg tttttgctaa tgtttgtgct aaaaatgttt
     7261 taccagaccc tgtaggtccg atcaagcaga tattgctttt ttgcagttca acatcatctg
     7321 tgttttcttg tgcttgctga ttgacacgtt tatagtgatt gtatacggca acagctaacg
     7381 agcgttttgc gcgatcttgt ccaatcacgt agttattcaa tacttcaaga atttctagtg
     7441 gtttagggac ttcagtgaat tcgcgtacag cttcttcata aaattcttca tcaatgattt
     7501 ctttacatag gtcgatacat tcattacaga tgtagacccc tggaccagct acgatctttt
     7561 tcacttcttc ttgggttttc ccgcaaaaag aacagcgtac ggtctcattg ctacttggat
     7621 tgtcatacat ggtcttcacc ccttaacttg caaaaagtat gcaagaaact atcaaagact
     7681 ttacagtctt ttactatcat aacatagttt agtaaaaaga aaaagtgttt aacaaaggat
     7741 caactgacct atacctttgc attttttact cttaacaaaa aataaggaac tgtgacaaaa
     7801 tcgtgtcaca gtcccttatt tcgaataaac aattttctag aagtagcttc ttcagaaatg
     7861 atttattact tgatttctat tctttcgctt ctgtcgctgt acctgtgatc aattcgattg
     7921 cttttttcat tgtcacatca tgttccagca tatcttctgt caacacgcgt ttgatttgtt
     7981 cgattggcat gttgtatgtt tctgataatt cttggatttc tgcattgatt tcttcttctg
     8041 ttgcttgaag attttcagca gctgcaattg cttcgatcac aagatttgtt cttgtgcgca
     8101 tttctgcttc accttcgaat tgtttatgca agtcttcttc tgtagaacca gttaattgat
     8161 agtacatttc aggagagata ccttgacgtt gcatgttgtt caagaattcg tccattgaac
     8221 gatgtacttc atcatgaacc atcacgtgtg gcaattcaac gatttctgcg ttttcaacag
     8281 ccatacggat cgctgcttca tcttttgcat cgtccgctgc tttttctttt gtttctacta
     8341 attctttgcg atatttttct ttcaattcgt ctaatgttga tacttcgtca tcaacatctt
     8401 ttgcgaattc gtcatctaat tcaggcactt cttttgcttt tacttcatgg attgtcactt
     8461 tgaagactgc ttcttttcca gcaagatctt ctgcttgata atcttctggg aaagttacat
     8521 ttacatctag actttcacct gatttatgac caactaattg atcttcaaaa cctggaatga
     8581 atgagcctga acctaattca agtgagtaat tttcgccttt tccgccatca aacgcttcgc
     8641 catctacaaa gccttcgaag tcgattacta ctgtatcgcc attttcagct gcagcatctt
     8701 ctttgataac taattcagct tgtgcttctt gttcacgttt gatacgtgca tccacgtcag
     8761 catctgttac ttcacggtct tgtttttcaa caactagatc tttatattgt cctaatttta
     8821 cttctggttt cactgttact tcagcagtga ttacccagtc ttgacctttt tccatgcttt
     8881 caacatcgat ttttggttga gaaacaggat cgatgccagc ttctttgaca gcagcttcat
     8941 aagcttctgg taatacagca ttcaatgcat cttcatataa agcttcttca ccgtacatac
     9001 ggttgaatac ttgacgagaa actttccctt tacggaatcc aggtacgttc aagctttttt
     9061 tcactttatt aaacgcagtt gttaatcctt tttggatttc gtcttgcgca atcgtaaatt
     9121 ttaaaacacc atcattcgtg cctttttttt caaatgttgc agtcatttaa ttccctccga
     9181 gtttagaaat tcattttata catcaaaaac gtttcatgca tacctttaaa tagtacacta
     9241 accctttcaa attgtaaaca tattgaatgg atagaatcct tgtttttcat aacattttta
     9301 tctttttcac tgataaaatc taatggaaga agatcatttg ctgcaaaatt ttttctcttt
     9361 tttttaaaaa atcttgtttt tcatcttctg taccttcata catcgttttt cctgtacacg
     9421 cctctacagt cagttgaaac cagcgcttcg ggtcttcgat gtatgtatca tagacaggat
     9481 aaacaattgc agattgcaac gtgaattctt cttttaacac ggaactaagc agcgcatctt
     9541 cattcccgta acgatctgaa aatacacata attgctggta acttgcctgc tgctgcggct
     9601 ttggcagatc ttttggtatg actttgacta acttttcttc aatcgtcaaa tagaaaacag
     9661 gatggcattc gttcaattgc ctaagtgtct ccagtaattt tgcccttgct aaaatatgga
     9721 cctctggcga tacaataagt ttactcgctg tttggataaa ctcatgataa ggaagctgtt
     9781 cgatctcatc aatagacgca agctgacgtg caggttccaa cgaaggaagt tcctccgatt
     9841 tattgtggag tgccttgatc ttctgcctct ccatttgtcc ggataattct tctgcaaatt
     9901 ggattttttc aatgacccgc tgctcgaaag cttcataaaa atctgtactt gctatcaatt
     9961 ttctagcata taaaaaatct tgtgtactga ttaacaagtc aaaataaaat tcagcaaact
    10021 cctcattttg aagatactgt ttttcatgca agagtgcttg cttcaatgct tcttttttct
    10081 cgtccaactc gtaaagacaa aaaacaagca ggctattagc ctcaaagctt tctttcaact
    10141 cgtaagctcg ttgaaataat tcttttgcct gctgatattg ctggtttgct agtgcttgtt
    10201 gtgccactcg cattaaattc tcatattttt ctggaaaatc aatcggcttc acgcagtgtc
    10261 ctcctcttgc tcatattcag ctcatgttca atagtagcaa aacaaaaaaa gcatgacaat
    10321 taaaaataac tgaagcaccc tctaaaagct agattttaga tctgactttt agaaggtgct
    10381 ttcaactgtt actgcttttt attgctcatc agctgttgac ttcctggttg aacgctttga
    10441 tcagattgat cgtaacaaca cttgtattag tgaaaaaatc gcccagatgt tgctttttct
    10501 gattaaagac tgctggaaga taccctaaca tcagcaaagg aaattttaga atgaaccggc
    10561 aagcaccttc tctaactaaa acggttgacc agctaagttc ttcttcatca aagctgatga
    10621 ctcgaatacc aaagatcatt ttcccaatcg tttggccatg attgaatttc gtcaataaaa
    10681 taaaatacgc tagataaata agtaaggctg tgaatccgta gagactcaga taagaatctg
    10741 aaaaattaag ccaacctaga tttttggcaa taccaagtgt taaacgcgta atagctccga
    10801 tacacaaaag atcgaccaag aaggcaaaca ttcggataaa aaaacctgca tagaaatact
    10861 taggaaaatc atttgctttt ggcggttcat ttcttgtgtc cgtatacttt ttccatttac
    10921 gttgtttctt tttgatttct tcgggcgtca aaggctctct ttcaaaagag ctcagtacct
    10981 tttgggaaaa gttggagtca ggtcctacag caggctgctg ttgcttatct ttttcttgtt
    11041 ccttattttc atttgaaagc tctgacatgc ttactcacct ccgtaataat acattgcttt
    11101 tggtgattcc gctgtcccta gattctcaag aacggataag atctgactag tctcagaagg
    11161 cttcaatccc tggaattctg ctagtttact tcctaaccat gtactagcaa acccagatgg
    11221 cgtggaagaa tattctacta gttccgcatc ttcaagctgt tgttcctttc gtatagcttt
    11281 taaagcatct tcaggaaatc ccaattcatc gactaaacct acttcttttg cttggacacc
    11341 atcataaatc cttccatcag caattttttt gacttcttct tcagatttat tccgtccctc
    11401 gctgacgatt gctacaaaac gactatatgc gctgtcgata tatgcttgaa gcaccgcttc
    11461 ttcttctttt gtctctggtc gcgttcctga acccatatct ttcaacgctc cgcttttaac
    11521 tgttgtatct tccacaccca gtttttctag aagtcctgaa taattcaatc ctgacatgat
    11581 cacaccaatt gagccggtca ctgtttcttc tgttgcaaag attttatctg cttgagcaga
    11641 aatatagtag ccaccgctag ctgccatgtt tttcatgctg acatacattg ggatatcatg
    11701 ttctttacga atcgtatcca atttcttagc gatttccgca ctttcgtaga caccgccacc
    11761 aggagaattt acttctaaaa agataccttt gactgttgga tcttcttcaa tcgccttcag
    11821 ttgttccata aaatttttat gattgtaacc ttcagaagca aataaacctg aagaccctcc
    11881 cgcagcaatc gttccatcta ctgataattt tacgattttt tgcgtactgt ctccctcttc
    11941 caacacattt ggagctagtt cttcatcccc atataaccaa ctgttcaatc cctcaatttg
    12001 atcgttttcc tgaggcttag tcaaactagc tgaaactaac gaaaccacaa ataatcctgc
    12061 agcaatcaga actgctgccc aacgtctttt attcattctt tctcctttct aatacaagtt
    12121 ttttatgacg atcacagttt ctgactgctc agaagtgtcg aaccgctctg ctttttcttc
    12181 ccgcgcatac ccggaaaacg actcttttgt taattcatct tctaccgtaa actcacgagc
    12241 ttgagcaact tccaaggcat caggtgcgat ttcttggatg ctatcccagc cagtatctaa
    12301 aaatattttc gtatcatctg atacaccagc tgatgcttcg aatttggaca attgtttttt
    12361 taacattccc agtgtcatga tctcaatttt tgaatccatt tttactcctc ctctatccga
    12421 ttactttcta ttgtaccgaa ctcctgaaaa agatgataga taaaaaccca ttattttttg
    12481 acataaaaag gacatttgac aaagaatttg atatatacca atttattttt tattcttttt
    12541 ttgttgacaa gaacattcgc aaaaggttat gattttaaat gtttccagat aaaaaacaaa
    12601 aaggaggata gttatacctt ttaggatagc gccaggtctg tgtaaacaga tgacgaggag
    12661 agggtttatc gaaagattcg gcggatggcc ctagggactg cactctacag aaaatccaca
    12721 aaaaatgtct gcaaagataa aacaaaagga ttttcctgca gctggaagca ttcatacgaa
    12781 ttcattatag aaagtaggat gttttttatg tgcggaattg ttggaatgat tggattaaaa
    12841 aatgtaacac caggattgat tgacggtcta gaaaaattag aataccgtgg ttatgattca
    12901 gctggtatct ttgtctcaga tggcacaact gattatctgg tcaaagcaca aggcagaatt
    12961 caaaatttga aaaacaaaat aaatattgat actacaggaa atataggtat tggtcataca
    13021 cgatgggcaa ctcacgggca accttctgaa gaaaacgccc atccacatac ttcccaaagt
    13081 ggacgcttcg tgctcgttca caacggcgta atcgaaaact ttgaagaact taaaattgct
    13141 tatttagcaa atgaccactt tattggtgag accgatactg agattatcgc tcatctaatt
    13201 gaaactttcg cgaaggatac tacaacgcaa gaggcgtttt taaaagcttt gcgggtcatc
    13261 aaaggttctt acgctttcgc tttgattgat cggacagcac ctgatgttat ttacgtcgct
    13321 aaaaataaaa gtccactatt aatcggactc ggcgatggat tcaatgtgat tgccagcgat
    13381 gcaatggcta tgcttgctca tacgaaggaa ttcgttgaga ttgaagatga agagatggtt
    13441 accgtcacat cagaaaaagt tattattcaa aattttgcag gtgacatcgt agaacgttct
    13501 tcattcgaag cacaagtaga tgcttcagat atcgagaaag gtacctatcc tttttatatg
    13561 ctgaaagaaa tcgacgaaca gcctattatc atgcgtcgta tcgctcaaaa atacgtaaca
    13621 gaagacaatc gtgtctctct tgatcaaaag ctggtcgata cattgtctga tagcgatcga
    13681 atctatatcg ttgcttgcgg aactagttac catgcggggt tagcaggtaa acagactttg
    13741 gaaaaattga cacagattcc tgttgaggtt catttagcca gtgaatttgg ctataacaca
    13801 cctcttcttt caaaaaaacc attctttatt ttcttgagtc aaagtggcga aacagcagac
    13861 agccgccaag tgctggtaaa aatcaaccgt ctcggctacc cttcacttac gattacaaat
    13921 gttgctggtt ctactctttc gcgggaagca tcctttacac tgctattgca tgctggaccc
    13981 gaaatcgcag tagcatcaac gaaagcttat actgcacaaa tagctgtact aactttatta
    14041 gccaaagcta tcggtgataa aaaagaattt gaaacttctc ttgtattcga tatcactcat
    14101 gaattgagtt tagttgctaa tgcgatggaa tcggtcatcg cccaaaaaga ttatttagaa
    14161 gagttggcag aagtatatct cagcgataca agaaatgcct tttacattgg acgtggtgct
    14221 gactacaacg tttctcttga agctgctttg aaattgaaag aaatcagtta tatccaggca
    14281 gaaggttttg ccgctggcga attgaaacat ggaacgattg ctttgatcga agaaggaaca
    14341 ccagtgatcg gaatcatcag tgaagaagtg actggtgcgc atactcgagg aaacctgaaa
    14401 gaagtcgaaa gccgtggcgc taaaacacta gttattgtct cagagggatt agaaaaggaa
    14461 agtgaccagc tggtgctacc aactgtccac ccttatctaa ctactctaac cacagtcgta
    14521 ccgactcaat tacttgcata ttacgcaacg ctattacggg gattcgacgt tgacaaacca
    14581 cgtaatttag cgaaatcagt gacagtagaa taataaaaga acaaggacca gtgtcagaca
    14641 tctgacactg gtccttgttc ttttattttt tatgaaaata tctcttaatc cagtccgatt
    14701 tcttctttga ctactgccgc gattttatcg acatagtaat taactttctc atcagtaggc
    14761 gcttctgcca tcactcgaag taatggttct gtaccggaag gacgaactag gattcttcct
    14821 tctgatccca tttcagcttc tgcctcttca atcacttttt tgattgccgg aacatccatc
    14881 gcaccgtttt tatcacttac gcggatattc actaattttt gcggatagat tgttacctct
    14941 gctgcaagct ctgataattt cttacctgtc tgtttcatga tattcagtaa ctgaattcct
    15001 gaaagcatcc catctccagt tgtgttaaaa tctaagaaaa tcatgtgccc agactgctcg
    15061 ccgccaaagt tataatcgtt tttgcgcatt tcttctacaa cgtaacgatc accaacttgt
    15121 gtaacgacat ctttcaaacc gattccttcc accgctttgt ggaatcctaa gttactcatg
    15181 acagtcgtaa cgatcgtatc ttttttcaat cgattttttt ctgccaagta tttagcacag
    15241 ataaacatga ttttatcacc gtcgacaatg tttccaagtt catccaccgc aataatacga
    15301 tcgccatcgc catcgaaagc tagtccagca tctgctcctt tttcaacgac catctcagct
    15361 aaacgttctg gatgggtaga gcctacgccg tcattgatat ttaacccgtc tggatttgtg
    15421 cccattgtat aaaaatctgt ttcaagatcg gcaaacaaac gattaacact tgttgaagtt
    15481 gctccgtttg ctgcatcgac acaaatggtc aaaccggaaa ggtcaccgtt gatcgtttgt
    15541 acaaggaatt gagaatattt caataagcct tctggaaatt cttctacagt tcccaatcct
    15601 tcagctgatg gacgaggcaa ttcatccact tcagcatcta ataatgcttc aatttctagc
    15661 tcttggtcat ctactagttt aaaaccatct gcaccgaaaa atttgattcc attatcttgt
    15721 gctggattat gagaagcaga aatcatgacc cctgcgcttg ctttttgcaa acgtgtcaga
    15781 taagcaacac ctggtgtaga gatcacacct agctggaaca cttcgatacc caccgataaa
    15841 agtcctgaaa tcagcgcttc ttctaacatt tgacctgaga ttcttgtatc ccgccctact
    15901 aacacgcgtg ggcgttttcc ttcttcttca tgctggctta ggacataacc tccgcaccgt
    15961 cccagcttaa atgcaagttc tggcgtaagt tccttgttgg cttcaccgcg tacgccgtct
    16021 gttccaaaat atttacccat agttgtaaaa ttactccttt aacttaattt tctgaggaat
    16081 ttgttctgct catttgtgtt gattcgcttg tttctgatgt ttcttctgta cttgtggtcg
    16141 agctgcttgt cccagattcc gaactggaag aaatggttgt tgtcgatggt tccgttcctg
    16201 aatcagcaga tgaaatactt ctactcgtac ttgtattttc ttgtgtccga ctgctcgtcg
    16261 aagcagagct actgcttgac gtttgcaaca cgggtgtaat ctccacacta actgattcgg
    16321 gcttgatact taacccctct tctactggta tttcaatttt acgagttgtt cgatgattga
    16381 tacctgagac attgatcggt acagcaatac tgtcaccgat cgatgcaagc aaatcgctag
    16441 agccgcttac ttctgcttcc agttttgaaa aactgaaatc atagctttct accccggcag
    16501 ctggtgttcc ttgctgtatc ccataaagtc gtaccgactt gcttggcttg atcgaatcag
    16561 ctctcactgt tacttgcact ggatcagaga cgatacttaa tacttcccct gctgcattca
    16621 gcgcctgtat tgggacctca ctattaatcc catcatctgt gaccatcgaa gcgtccacat
    16681 cagctactac tcgtttgatt tctgccaatg ttttgtcacc tgtagtgata gagacttttt
    16741 taggactaac ggaagtatca tcaagttcat atccagatgg tgtgaacgtt gaaggaatca
    16801 acgtttccac atcgaaatct tttattacct ttttctcaac cgttactgta atagtcgatg
    16861 gttcgatctt tgctgtgaca gcactgctca aattttgaat ttttagcgga acttcatgtg
    16921 ttccttcgcc cagcttagtg atatctgctg tgacgcggaa catccgtgta tcttcgtttg
    16981 cctctgcatt caactgaact cggtttgcac tggaaagttt gacagtcact gcattttcat
    17041 atccatggat atagtagcgc tttgaatcat aagaaatctt gatcggcacc cccgtaactg
    17101 tttgattata cgcttcattt ccagaaagcg tatttggaac ggactggcca tttgcattga
    17161 agtacagcgc aatactgaac agcaatgcaa taaaactgta aagaatgctt gtccgtttct
    17221 cttttgagat catttgcgat cccctccctt agtcataccg tctaggaaag attgaatcac
    17281 gtttttcttg ttttttgttt tctcttcagc aattagttct ctacgcaaga ttgccaaata
    17341 ttcttgctgg gataagccag ccatcagttc attatctaac gtgatgctga cgtccccggt
    17401 ttcttcagag acaacgatgg taatcgcgtc actgacttcg cttataccga cagctgcccg
    17461 gtgtcgagtc ccgaattctt tagggatcaa catactttct gatagaggaa gataggcgct
    17521 tgctactgcg atctttcctt cttttacaat aactgcaccg tcatgcagcg gtgtattagg
    17581 aataaagata ttgatcagca gctccccagt gatatctgca tctaaagcaa tccctgtctc
    17641 aatatactca tctaatccag tatgacgttc gatagtgatc aacgcaccga tttttcgctt
    17701 ggacatatat tggatggctt tgtcaaaaga caagatcatc ttctcatctt cctgctgttc
    17761 gctttttgat tgtttgaaaa gcgaactgcg tccaagatgt tccagtcctc tccggatttc
    17821 cggctgaaaa atcacgatag cagctatcac cccgtacgta atgacttggt tcatcagcca
    17881 agacaaggtg tgcagaccaa tgatttccgc tacgattcgg ataacaataa aaatagctac
    17941 acctttcaga agctgaatcg cttttgtgcc tcgcagcagt tggatcagtt tgtatacaag
    18001 ataccagaca accagaatat caagtatgtt caccaaaaaa ttcagagaga acaagtcacc
    18061 ggaaaacatt tgctgccaat agtccaaatt aaaaagttcc ccgatttgaa atgacataaa
    18121 aagcctctct tctcttttga gatttcctct ctagtatatc atatgtttta attttagagg
    18181 ctgatatgct cgtatttttc ttgagaaaaa cgcataattt tcaagaaaat tgcaagtatg
    18241 cgttttattt ttctctgcaa taaatatttt taaacttcag agaattattc attatatttt
    18301 ttctgttatt tttccttttt ttcttttgta gcttgttcca tttttttacg tcgttctgct
    18361 ctggcagctc ttctagcagc tcttctttct tctgcttcaa ggtccgtcgt tttttctttt
    18421 ctagtcttaa cgggtacatc gatagattcc tctggttcaa gtcgtttctt gattttttct
    18481 aattctcccg tcagtgcagc atagttgtaa aaacgtgttt tagcgtcgtg gacagtcttt
    18541 tcaaataaag cttttgcaag atttggattt gcgttatcta gcgaggaaaa gcgaacttgt
    18601 ttcctcatga aatcaggcat agcagagaaa tcaggttttt tgtagtccaa agtcattggg
    18661 ttcttgtttt tttcgaccat tgtagggtta tatcgatata atgaccaata accagaagaa
    18721 acagcttctt ttgcttcttt aagcgattct ttcattccgc caagcaagcc atgtgtgata
    18781 caaggcgtat aggcaataat cagagaagga ccaggatact tttctgcttc ttcaaatgcc
    18841 ttgatcgttt gcatttgatt ggcacctgaa gcaatttgcg ccacataaac atttccatat
    18901 gtcatcgcca tcattcctag atctttcttt gaagcatact ttccactagc cgaaaattta
    18961 gcgattgccg aagctggtgt tgcttttgag gtttgaccgc cagtattgga atagacttcg
    19021 ttatccaaaa caaggatatt cacgtctgct ccgctggcaa gtacatgatc gatcccgcca
    19081 aaaccaatgt cgtaagccca tccgtctcca ccaatcatcc attggctgtt ttttacgaat
    19141 agatcctttc tcttgtatat atcctccagt tcagggaaaa ttgatcgttc gctttcgatc
    19201 gcagcttgca gttttgctgc tctttgctgc gttccttcac tctcaaacat gtgtactaac
    19261 cagtcttcca tcaattctcg tagttcttct gatacttttg gcaatacttc tttgattgaa
    19321 cttgccaaag cctcgcgacg agtctgtgcc gctagaagca taccataacc aaattcagca
    19381 ttatcttcca ataaagaatt tgaccatgca ggcccttgac cacattcatt ggtcgtataa
    19441 ggagaagcag gagaagcacc gccccaaata gaagaacagc ctgtcgcatt cgcgatcatc
    19501 attcgatcac cgaacatttg tgtcaataat tttacataag gtgtttcgcc acagcctgag
    19561 caagcgcccg agaattcaag aagcggttga ttgaattgtg tagacaagac agtattcttt
    19621 cctttgactg gatttgcttt ttgtcttaat gtcattgcaa aagcccaatt cacagcttgt
    19681 tctttctgtt cttcataagg cttcatcact aaagcttttt cttttgcggg acaagcctct
    19741 acacacagac cacaacctgt acagtcttcc actgaaactt ggatacggta ttttacgccg
    19801 tctgcgcctc gcatttctct cacgataaat ccttctggcg cttcttccat ttcctcttca
    19861 tctgctaaaa atggacggat ggcagcatga ggacaaacaa aggcacattc attacacatc
    19921 gtacagcgat cactaatcca ctcaggtact tctaaagcga cgccccgctt ttccatagaa
    19981 gccgttccta aaggcatttc gccagttgtc attccatttg ctacaagtgt accaacagag
    20041 agttgatttc cttcctgtgc attcactggt tcaagtattt cttgtatata accagtgttc
    20101 cttttattga ttttttcagg catctccaac gttctccaat ggtctgggat cgcgacttga
    20161 tgaagcagtt cggtcgtccg atcgattgct tgtatgtttt tttctacgat agccattgat
    20221 ttatgtccat agcttttcag ggcttcttct tttagcagcg gaagcacctc atcaaaagga
    20281 atgatgtcag ctaatttaaa aaaagccgtt tccattgccg tattgatccg gcgtcccaaa
    20341 ccgacttctt gggccaatct catggcattg atcgtataga atctaatgtt attttcagcc
    20401 aagtaacgtt ttaattttaa gggcagatgc gtttctaatt gttcgtcgct ccaaagagta
    20461 ttcaataaaa aaatgccacc tggcttcaat cctttgacca agtcatagct atgcaggtaa
    20521 gctggtgtgt gacaggcaac aaggtccgca tgctcgacaa gatacgctga acgtatcggc
    20581 gtatctccaa aacgaagatg agagacagtc agaccgccag attttttcga atcataataa
    20641 aaatagcctt gcgcatattt atcggtgtga tctccaataa tcttgatagc tgatttattt
    20701 gctccaactg ttccgtcaga tccaaatccc caaaacttgg cctggaatgt ttgcggttct
    20761 gtcaaatcca gactttcctt tggttccaaa gattgataag tcacatcatc cacgatccct
    20821 atggtaaacc gttttttgcg tatgcttggg tcttttttca attcatcaaa aactgctgag
    20881 atttggtcgg gagtcacatc tttagacccc aatccgtagc gaccaccaat aacagccggg
    20941 cgaagttcag aatcatataa cgcactttga acgtctaata agagaggttc tccacctgcc
    21001 cctggttctt tacttcgatc aagaacagca attgttttta ctgtatgagg caacttttgc
    21061 acgaatgttt ccactggaaa aggacgataa agatggatat tcaaaaaacc tgttttccgt
    21121 ccgtttgcat tcaagtaatc aatcgtttgt tcaatcgtct gtgcaactga tcccatagaa
    21181 acaatgactt cttccgcatc gtctgctccg taataagtca ccaagtcata agaagttcct
    21241 cgtaatcggt tgatctcttt catatatttt tgaacgattt caggtaattt atcataatag
    21301 gggttgatcg tttcccgttg ttgaaaatgg atgtctggat tctggttcgt accactaaca
    21361 gtcggatgat tgggattcat ccctcgttta cgaaatgaag ctaatttctc ctgattgatc
    21421 agaggagcta attcttcata ttccaaaact tcgatttttt gaatctcgtg actcgtacgg
    21481 aatccatcaa agaaattcaa aaaagggact tctccttcaa tagaagcaag atgggcaaca
    21541 ggtgctaaat ccatcacttc ttgtacactg ctttcagcta acatagcaaa tcctgtttgt
    21601 cttgcagcca tcacgtctcc gtgatctccg aaaatattca acgcatttgt cgtcactgcc
    21661 cgactagcaa cgtggaaaac acttggcagt agttccccag caatcttgta catattcggt
    21721 atcatcaaaa gcagcccttg tgaagcggta tatgtagttg tcagtgcacc agttttcaat
    21781 gatccatgga ccacaccagc tgctcctgct tcggattgca tttctactac ttttactggt
    21841 tgaccgaata cgttttcttt tcctgctgct gaccattgat ctactaattc agccatggtc
    21901 gaactgggtg ttattggata tattgcagca atctcggtaa atgcataaga aatatatgcg
    21961 gctgccgtat tgccatccat tgttttcatt tttcgcatga ttcatcatcc ttgttcatat
    22021 tctctcttat tatctgttcc attataacgt aaaacatgcc atttttttct tttatttata
    22081 aaaatatttt acatgtatct atttgaattg gtcatctaat ttttagacaa acagtctaaa
    22141 tcgttgcctt tttttgtcag acatgtataa actataagcg aaagaggtgt tttaacatgg
    22201 atatatcagt gattgatgca acgaaaacaa atacacaaaa aggaatcctt tatggttcat
    22261 cgaatgctcc taaaaaaatg gtcgaattca tcaacttagc ttgtccgtat tgccgacaat
    22321 ggtttgaaga atcttatgag ctattagaag aagcagtcca aagcgggcaa ttgcagcgag
    22381 tgatcaaatt gttcgataaa gaaaaagaaa gcttacagcg agggaacgtg atgcaccggt
    22441 atctcacaat cagcgatggc caaaaagcga tcaaagagat caaacaaata ttcgatactc
    22501 aagacgagtg gaaacatctt tctctccaag aagtagcgga ttttgcagta gataaactaa
    22561 agctgacaga acaaaaagac gaacagctga gccaagctgt catcaacgaa gctgagcaag
    22621 cacatattcg atttgttcca actgtcatct tgggtaaaga aatctttgat gaatctattt
    22681 caatagagga attaaaagaa ttgatccaaa caaaataaaa aaataaggag cgtgggacaa
    22741 aagtaaagaa cacttttgtc tcacgctcta aacacgtata aacggcggaa gcagaagcaa
    22801 ctccttctta tttcttggag ttaaacgctt ctgtcccagc ctccttattc cgaataaatg
    22861 gtgtccaaaa gcttgcatct gccagattat ctcatttctt atgacaagct aagcaaatta
    22921 tctccaccaa ataatttatt catatttttg acttgcgcat actaactaat tcttaaattt
    22981 tcatacaaaa tttctcaatt tcccttaacg agtaatattt atgtacggtg attctcacta
    23041 gtatcccaat cactttttaa gttatcccga tttcaattct acttcaaaaa tagttgcttt
    23101 tatgtatgct gttagttgat tagatggtca tttgttgagc taggtcgttt attttaaaca
    23161 agttgtttct ttagcttata cctatctcgt ctaccaaacg caagatggca aacacaaatg
    23221 catacgcatc tgtatttgcc actttgattc gtataaagct aacaactatt aactcctctc
    23281 agctaatagt tgctctcttt tttattcaga ttcatttttg ctgatcacag cctagtattt
    23341 caatggtttt gaacactaaa ccaaattgtt ccattacaac attcactggc tgatgaaatg
    23401 gattagtaga tttcgattat tcaaagcgat tttctattgg tggatcgtgt tcccaactaa
    23461 taagacggat tccaaaccta tcgtacagat cttctaaacc acttataaat tttgcaccta
    23521 tttcaggtgt tttattgcgt ggatattcta ttgttacgcc attaaatgga taccaattag
    23581 gattaggctc tctttttttc tgtacatctc ccatagaata gttagcactt tctgggacat
    23641 aatatattct tcgaccatcc tctaattcat ctaataagat atttcgtgat cgtctatcac
    23701 ttgctaaatg tagacgccac gtgcgatacc atgccatgct acctgcatct gcagaaaatc
    23761 catcaaataa tgcaacaatt gtatcttcta tcacaatcct ttccccatct acttcatatt
    23821 ctaatctaaa atcaaactcc cctcgggtaa tttctggtct tggtggctta ggacccaata
    23881 ttattctact taaaaccgca ttcgttccca gatgaaacac agctataaca acaataatga
    23941 ttaatatttt gtttctattt gataaatttc tcattattcg cacatcacct ctacattctc
    24001 acatattagt tcgtaatact cctttaatat caaaatatct actggtcgta ataatattcg
    24061 ctatgaattc ctactactcg tataagaaag gccaaatcat cagcttttac ttgctgatga
    24121 tttggcttgt ttctatttat cgtaattgtt ttctaatcac caaaattgtt aacaatcggt
    24181 tcagatattt cccagttgat taaggtaatt ccgtattgtg tcaaaacttc ttgcgcttct
    24241 ccgaaattaa gtacagttct tatgtatcca ctttctccta atataaagtc tacctctctt
    24301 ttaaaacctt cctcgagatt tctaagggct atatgtggtt ttaatgacat tgattgtaca
    24361 ttttccccca tataatattg cgcacttcct cgactaaaat agattcctag atcgtcccca
    24421 aaaggtagat cttctctacc actagctaat ctacttctcc atcttcgttc tcttttcata
    24481 gaacctgcgc tgaactcaca cccgttaaac tcagctatga cagtatcttc aattatgtta
    24541 atctgtccat ctagttcgta ttcaatccta aatggaaatt ctccataggt gatttccggt
    24601 tcgggtattt taggtgagat taatgcaaag aaaggaaata ttaagcttgg caacatcaaa
    24661 aaaactcctc ctatgatcac aattcccgat gtaatccaaa atataatttg tacaattctc
    24721 attgatccat tgtattccat tttattcccc ctattactat tcatatccgc ctatctatat
    24781 cgatcttcca atgcagagat aattgcttcc ataccttgat tttttactga gttacctatg
    24841 cgagatatca ttctccacta aggtgcatca tattgtctat ctaacatgat taattctcca
    24901 ataggtgtat actcctccaa aaacaacatt taatgcatct ccctcgacaa cataagctac
    24961 catgtttgct gtatatgtgt ttgagtctaa ttcataagca gataaattta ctgtcgctgg
    25021 attaaatata atcgcattcg tatttatagc tactgaattt gctgcttcag caccaccttt
    25081 tgaatgtccg atcattgtga tttcaatagt aggatttacg tggacagccc tcaccgttta
    25141 ccctgaccat tatagaaatc gcttactttt ttgaactacg caacaaagga tacaatgctc
    25201 ctaacttcac tgtctccatt tttgtccact aaggaatata aaaaataggc attaattcat
    25261 ttaattcggt cacaacacgt taccttttaa atcattatac tgtatctcat acattattat
    25321 caataaacta ttataaaaat gcaaaaaatg ctttatcaat ctattttgta attggtcata
    25381 atatcattga aatcataccc tgtatcgatt tttcctatga atctcgtcta tttgtgattg
    25441 acgaaaaaga ggcaagacag acactggaat ggtaatttta cccactattt tgctccaact
    25501 atttgtaatc gtacccactt ttgaaatacc gagatgatca ttttaattga tatgctgatt
    25561 cccaagcaaa accccaagaa attaaatgct ctatcgcatc tagcttcttg ggttttgctt
    25621 atataaattc caacatttaa attttttatg ctgttcggtc tcagaaatgc cgtttttgct
    25681 tatatcacaa tatcaagatg tcaaattatt cgtgttgccg atgactttga ttaatttttt
    25741 tcaaattgtt tattaagact aatgctgtct ttttgcagat accaatgttc gaacttttta
    25801 acattatcat atgatcctgc aagttttaac ttcttaccat tagatgttat caaagttata
    25861 attaaccttg cctttttccc attaggatct tttattttat gaattttctg caggtaatct
    25921 ctcctaatgg cagctatttt tacctcatca gtgctgataa accattgatc atccacatac
    25981 atactgcctg ttatgttgtg tttttccatt tcttccgaga acgaaaagtt taaggctcgt
    26041 tcttacttcc aaagttgaat gagtccatgg attggactta gtgtgagaat tgagaacaac
    26101 aataagaatc catatcctcc cgcaaacatc cctaaggcta tactgtctct ccatccataa
    26161 gtaggattag aagagaaaag agtcaccgtt tgtaataata tgaaaaggaa taatccagca
    26221 caaacaccaa agataacaac tccaaacatt gaatttttat acaatgacca tttatttata
    26281 ggcttttctt tcattttact tccccctact gttctgttca cacggaatga attcaaagtt
    26341 cataagccct cctctttgaa catatgaata cgacttgcta actatacttt aaaaaagctt
    26401 gttttaagcg gttataggcg agttgtaatc tctattcatc tcattagcaa ataacttgcc
    26461 gaaaagtcta ctgaaattaa agcagatagt ggaagaatta tttagccagg atagacacta
    26521 tttgtgaaac acatgtcttt acttttgaaa ttctatgatg aaaagccttg gaatacagta
    26581 gctcttaatt ggtaatactt tttccattat aaataacctc ttttcatttt atatttatcc
    26641 cctctaaaaa taatatctaa tctaatattt taaacttata tttccctcgc tgtgctaata
    26701 gagcattact aaataaatag aaactagaaa aaagcattac gcctgccaga ataaaccaat
    26761 tatttgta
//
LOCUS       DAIGSZ010000040        26160 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.040, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000040 DAIGSZ010000000
VERSION     DAIGSZ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.040"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(62..1093)
                     /gene="queA"
                     /locus_tag="NOB31_001737"
     CDS             complement(62..1093)
                     /gene="queA"
                     /locus_tag="NOB31_001737"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HCI0973945.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1286..2461
                     /locus_tag="NOB31_001738"
     CDS             1286..2461
                     /locus_tag="NOB31_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0973946.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2465..3106
                     /locus_tag="NOB31_001739"
     CDS             2465..3106
                     /locus_tag="NOB31_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973947.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3103..4020
                     /locus_tag="NOB31_001740"
     CDS             3103..4020
                     /locus_tag="NOB31_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0973948.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4017..4688
                     /locus_tag="NOB31_001741"
     CDS             4017..4688
                     /locus_tag="NOB31_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0973949.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5229..5717)
                     /locus_tag="NOB31_001742"
     CDS             complement(5229..5717)
                     /locus_tag="NOB31_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HCI0973950.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5918..6184)
                     /locus_tag="NOB31_001743"
     CDS             complement(5918..6184)
                     /locus_tag="NOB31_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCI0973951.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6184..6447)
                     /locus_tag="NOB31_001744"
     CDS             complement(6184..6447)
                     /locus_tag="NOB31_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0973952.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            6923..7108
                     /locus_tag="NOB31_001745"
     CDS             6923..7108
                     /locus_tag="NOB31_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0973953.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(7250..9073)
                     /locus_tag="NOB31_001746"
     CDS             complement(7250..9073)
                     /locus_tag="NOB31_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HCI0973954.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9671..12376)
                     /locus_tag="NOB31_001747"
     CDS             complement(9671..12376)
                     /locus_tag="NOB31_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HCI0973955.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12682..13629)
                     /locus_tag="NOB31_001748"
     CDS             complement(12682..13629)
                     /locus_tag="NOB31_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HCI0973956.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13819..14088
                     /gene="rpsN"
                     /locus_tag="NOB31_001749"
     CDS             13819..14088
                     /gene="rpsN"
                     /locus_tag="NOB31_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCI0973957.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14264..14626)
                     /locus_tag="NOB31_001750"
     CDS             complement(14264..14626)
                     /locus_tag="NOB31_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI0973958.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14637..15758)
                     /locus_tag="NOB31_001751"
     CDS             complement(14637..15758)
                     /locus_tag="NOB31_001751"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCI0973959.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15774..16124)
                     /locus_tag="NOB31_001752"
     CDS             complement(15774..16124)
                     /locus_tag="NOB31_001752"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HCI0973960.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16254..17765)
                     /locus_tag="NOB31_001753"
     CDS             complement(16254..17765)
                     /locus_tag="NOB31_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCI0973961.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18087..19439)
                     /locus_tag="NOB31_001754"
     CDS             complement(18087..19439)
                     /locus_tag="NOB31_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HCI0973962.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19592..20668)
                     /locus_tag="NOB31_001755"
     CDS             complement(19592..20668)
                     /locus_tag="NOB31_001755"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HCI0973963.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20864..22609
                     /locus_tag="NOB31_001756"
     CDS             20864..22609
                     /locus_tag="NOB31_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HCI0973964.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22889..23326)
                     /locus_tag="NOB31_001757"
     CDS             complement(22889..23326)
                     /locus_tag="NOB31_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HCI0973965.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23310..24683)
                     /locus_tag="NOB31_001758"
     CDS             complement(23310..24683)
                     /locus_tag="NOB31_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973966.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25005..25493)
                     /locus_tag="NOB31_001759"
     CDS             complement(25005..25493)
                     /locus_tag="NOB31_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0973967.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25515..26117)
                     /locus_tag="NOB31_001760"
     CDS             complement(25515..26117)
                     /locus_tag="NOB31_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI0973968.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7503 a         5561 c         4838 g         8258 t
ORIGIN      
        1 ctttgtcata aaatctttgt aaagcttttt tgttattcaa aactagcggc ttttcataac
       61 cttatttcac gaacatcgca tctccaaaac taaagaaacg atagcgctct tcaatcgcat
      121 gctggtaagc agataaagtc aattctcttc ctgcaaaggc actaactaac atgactaaag
      181 tcgattttgg caaatggaaa ttagttgaga aagcttctac cactttgaat tcatagccag
      241 gcgtaatgaa aatatcagtc catccgctgt ctgctttgat ttctccatta aatttcgttc
      301 caatcgtttc taatgttcga attgaagttg ttccgacagc cacgattttc ccgccatttt
      361 tacgtacttg gttcaatcgc tcagccgctt cttccgtcaa acggtagaat tcactatgca
      421 tatggtgttc ttcaatttta tctacgctga caggtcggaa tgtacctaac cctacatgta
      481 gtgtcagata gactaattca acaccctttg cttcgatctc atcaagtaat tctttcgtaa
      541 aatgcaatcc agctgttggc gctgcagcag aaccattttc tttcgcatag acagtttgat
      601 agcgatctgg gtcttccaga cgttctttga tatatggagg caatggcatt tctcccaatg
      661 attcaagaat ctctagaaaa attccttcat actcaaagtc aatgatccgt ccgccgtgtt
      721 ccaattcttc tttcactact gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa
      781 ctttggcacg tttcgcaggt ttgatcaatg tctcccacgt atctccttgt gtattcgtta
      841 gaagaaggac ttctaaatgc gcaccagtat ctggtttttc tccatataaa cgagcaggca
      901 gaactcgtgt attattcata actagcgcat caccaggctg taactcttca atgatttcat
      961 ggaaatgttt atcttccatc tctccagttt tccgatccaa aacaagtaaa cgagaatgat
     1021 cgcggtcttt taatggtgtt tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt
     1081 ctgttgttaa catatcgtca ctcactttct atcatgtgct tcatcattct atcatgtttt
     1141 tcgttctgtt ggcaaaatca gcactttttc acttctattt tttgttttcc taaataaaaa
     1201 aactacccta tttgtatttt ttcattgttt taggcatact agtaatagat agttcttcat
     1261 tgaaaataga aaaagaggtg gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa
     1321 aggtggaaaa gtcgctgtag aggacgtcaa tctttcattt gaaaagggtg agttcatttg
     1381 ttttatcggt acgagcggaa gcggaaaaac gacgacgatg cggatgatca accgaatgac
     1441 tgatccaaca caagggaaaa ttttgattga tggaaaatcc atccaagaaa ttgatccagt
     1501 ggaattgcga cgtcagatcg gctatgttat ccaaagtatt ggattgatgc ctcacatgac
     1561 gatccgtgaa aatatcactc ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa
     1621 taaaacagct gaaaaaatga ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta
     1681 cccacatgaa ttatctggtg gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc
     1741 gaatcaagat atcatcttga tggacgagcc attcggtgcg cttgatccaa tcactcgtga
     1801 ttccttgcaa gaccttgtca aagatttaca agagcgtttg ggaaaaacga tcgtatttgt
     1861 aacccatgac atggatgaag cgattaaact agcaagccgt atcgccatca tgagtgaagg
     1921 ccgtgtgatc caatttgata caccagaaaa tattttacgt catcctgcaa acgatttcgt
     1981 agaagagttg attggagaag atcgcctact acaagccaag ccaaatgcga caagagtcgg
     2041 cgaagttatg ctaaatacag caatcacgat tacaccggaa aaatcattac aagaagcaat
     2101 caaactgatg agggaaaaac gtgtagatac gttgttagtt accgataatt cgaatgtatt
     2161 aaaaggattt atcgatgtag aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg
     2221 cgacattttg aataaacatg ttttttacgt aaaagaatcc gcctatcttc gtgatacctt
     2281 gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc gttgatgaac agaacaaagt
     2341 cgtaggtatc ctgactcgtg catcattagt ggatatcgtc tacgatgtga tttggggaga
     2401 agatcccgca actactgatg ttgcagagtc agctactcct gaagaatcta aggaggtctg
     2461 acctatgcag cagttttttc atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca
     2521 tctttatatt tcaggacttg ctttgatcat tggtatcatc attgctgtac cgcttggtgt
     2581 cttactgaca cgttttccaa aagctgccac gattgtgatt ggcttaacca gtgccttgca
     2641 gacaatccct tctcttgctt tattggcatt gatgatcccg ctatttggcg taggtaaatt
     2701 acctgcgatt atcgcactct ttatttattc attattgccg attttacgta atacgtacat
     2761 tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca aaaggcatgg ggatgactga
     2821 gttccaatcc attttttccg ttgaattgcc cattgctatg ccaacgatca tggctggtat
     2881 tcgtttagct gccgtttacg tgattgcatg ggctacactt gcctcttata tcggcgctgg
     2941 tggtttaggc gatttgattt ttagtggact gaataattac caaccagatc tcattttggc
     3001 aggtacgatc cctgtaacaa ttttagcact attggctgat tggcttctag gtctcttgga
     3061 acaccggctg acaccgatcg cacttagaga ggagaatgaa gaatgaaacg tatactaaaa
     3121 atgaccatgg ttcttttctc tcttcttata cttgcgagtt gttccttccc tggtcttgcc
     3181 agcaatacag atgaagacac catttcgatc acaggtggaa tcacttcaga agcacagatc
     3241 ttagcaagtc tagttgccgg aatggttgaa cattatacag ataaaaatac cgcaatcatc
     3301 aacaatctgg ctactacaac tatcaaccat caagcgatga tgaacggaga tgcttcaatt
     3361 tcagcggctc gctacacagg aacagattta acgactacat tgaaccttcc tcctgaaaaa
     3421 gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg agaaaagata cggtcaaacg
     3481 tggttcccgt cctatggttt tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca
     3541 caaaaatacc atctatctaa agtcagcgat ctgaaaaatg tagcggatga attagtagct
     3601 ggtgtagata cttcttggat caatcgtaaa ggagacggtt atgacggctt ccaagaaact
     3661 tatggcttct ccttcaattc gatattacct atgcagattg gacttgttta tgacgcagtc
     3721 gaagcaggaa aaatggatat tgttcttggc tactctacgg atggacggat cgccagttat
     3781 gatctagtca tgttggaaga tgatcgtcaa ttcttcccac catatgatgc tgctccagtt
     3841 gtagacaaca agatattagc tgatacgcct catttaaaag aagccttaaa taagttaggt
     3901 cataccatca gtacggaaaa aatgcaggaa ttgaactacg aagcagataa taatctagtg
     3961 gaaccatcag tagtagcaca acgtttctta caagaaaacc actattttga agggaagtga
     4021 agcaattgga taaaatgaat gtctttcaac aatttttcta ttatttccag gaaaatggct
     4081 cctatatctt tgcacaattt atccgtcact tcctgatttc tatctatggt gtcctctttg
     4141 cagcagttgt cgggattccg gttgggatca tgatttctag gagacgtaaa ttagcaaact
     4201 gggtgattcg tttggcgaat atcatccaga cgatcccttc tctagccatg atctccattt
     4261 taatcattgg attaggcctg ggagtcaatg tcgtgattgt tactgtattt ttgtattccc
     4321 tcttaccgat catcaagaat acgtataccg ggatgatcca agtagacaaa aacatccttg
     4381 atgtcggcaa aggcatgggg atgactgcta gacaacgact attcatggta gagttaccac
     4441 tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt agttgttgcc atcgggataa
     4501 ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga tatcattatc cgaggaacca
     4561 atgcaacaga gggcacatcg attattttag caggtgcatt gccaactgca ttaatggcga
     4621 tcatcacgga ctggctttta ggtattttgg aaagacggct agatccagcc agccgtacat
     4681 cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct
     4741 tttttagttc tgtcattttt aaggcaataa tccactctga ttcttccctc cttatgggca
     4801 aagagttgct tttcttagct atttatccat tccgtatact ccaacttcat actgccaacg
     4861 ggttcatatc tgcatccacc gactaagttt ttttcttatc cgctaaggca ttttgccaat
     4921 ccattttccc atcactcgtc atggaattca taccacatga tctctaaata ctcgtctgct
     4981 tgttctttga attgggcatc aattcttaca tcctttggcg tggctttcat ttaagccttt
     5041 tccatcagtc ctcgattgtt cgatgccttc agctgcatca tcaaaactgg tgactgccgt
     5101 atcggtaact tcgatcatct tttatacaat cgggaacttg ccatcctcat ccttggctaa
     5161 aaacatatct agccattcca gcttctcgcc atgggaggtt tgcggttcct aaaaccggta
     5221 cacgattctt atggactgca tccgtcgcaa ctagacttgg cgatacgatg atccttcacc
     5281 agaagagcac ccccgtaaac caattgatcg atatattgcc aataagaaaa gacattggcg
     5341 taaaagatat cgatccctcg tgatgcattg ccgttgatac tgctattcat ggccgaaagc
     5401 gccacgactt taacttcttc cgtttgagtg acattcatgt tcggcaatgt cgctttggat
     5461 acccgctctg ctaaaggaac gacactggta ttgtatttcg tatctgtatc ttttccaaaa
     5521 gaccatgcca acgaatcctc tgggaaccaa taagacgact ccggttgatt gtccattgct
     5581 tttttcaaca tacttttggc tgtttctcga taaacgacat ttccaattgt cttcgcctca
     5641 ctttggcgat aatcgatggt cgttgccact gccaacacta acaacgatgc tccaatttta
     5701 ctgattttcc ttgtcacact tcttcctcct tgttttacat aaacccgtca acattccatt
     5761 cctaaactca aacaatgacc cttcaaaggt ggagatatag gaacaaatta aagaaatcat
     5821 gcaataaatc caagaaggtt ggttttagaa caaaaaaaga gtctcctttt tggggagact
     5881 ctttgttaac tatctaaaaa ggttggctct tctcacttca ctcataatgt gtccaggcag
     5941 aataaatttc tacaacttta ttttcctcat caactttgta aaccactcga tgctgtctat
     6001 tcagcctgcg tgagtatctg ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg
     6061 gcatatatgg atcttccttc aatgtctgaa tcacttcttc aaattgtttc tttaaattcg
     6121 tttgcttgat ttttcttaaa tccactttcg cagagttttt gattgcgact gtatagttac
     6181 tcatcaaaga gcttcccaat caatatcatc gatattcgta aagctactgt cgtctttttc
     6241 gcggtctcgt actttatcta aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc
     6301 tctccagtct tccagcccaa tcaatacagc attgtttcca ctacgatcac taataatctc
     6361 gatttcagta tgattttcat ttacctcttt caataactga taaaaatttt tacgagcagt
     6421 gctaggattc atcgttgtat tagccattgt ctctcctcct ttttctgata taattatagc
     6481 gtacttgatt aagtacgtca aaaaaataca ataaagcact taaattcagc aaacttttcc
     6541 tcttttttac atagagaaaa agaccccttt ttagggagga tctttgtcca cgctcacttc
     6601 ttactccttt acgactagcg gtagccaaac gtaaagtaat tggtaacaac gtatcatctt
     6661 tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca acaccaatac acgaaggttc
     6721 ctcgttgcag tgtgacttga ttgatatctt gaataacctg aggatacgca cgaaagattt
     6781 gtaacggtta ttcaaaactg attttggccg tcaagtcttc tactgcctca aaaatgattg
     6841 cctctttcgt ctcctgtcat tcatgttcac tatcgatttg atacttgctt agaccgttgg
     6901 gtttgtgaat caccaattaa aaatggcact gagttatggt aacaaaaaat ggtcacttga
     6961 cgaggctgag attcctactt atgaagacac atggcactta agagtcgagg taaaggaaga
     7021 agctgaaaat ataggaggct gtacattatt tggcaaagga ttcggaaatt atgatcaaga
     7081 catcaaaatc aaaatgtttt acagctaaat aggaagaata ataacatttc atacgctgtt
     7141 cccatcttta atggcttata gagggcacct ttagctgaga ataagacaaa acagaccctc
     7201 tagcttcaat taagagctag agggtctgtt tttgatttta aaacttggtt tatttcttca
     7261 aatggtagct ataggtgctg acaacgatat tttcacgcca agacaatcgc aatcttaacc
     7321 gcaaacttgt ttggttatgg agaatattct gccagcgtct gtttggtaca aattgaggaa
     7381 tcaacacagt agttgtatag ttttgtttcg ctgcattttt acttacgata tctacataac
     7441 ggataattgg attttcaatc gagcgataag aagagtggac gattgaaaaa cggacatctg
     7501 ggaaatgctt tttaaattct gcttcgattt ctttttcttt ttcgacatct tcgtctagcg
     7561 aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc gtaattcaac gcaccgatat
     7621 ttacccgtgt cacattcccg actaatacaa gaacggtatt cccgtcataa tcatgtagtt
     7681 ttgcatcatt ttctaaacga agctgttctg ctactttttt ataatgatca tggatcttat
     7741 aaaaaatgaa cataacgatt ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat
     7801 agacaaacaa aatcgcaatg attgcatatg agatgaacgc acccgtaata ttggcaatcg
     7861 atttgcttaa ccatcttttt ccttcttttt tccatttgac gaccatccct gtttgagata
     7921 aagcaaatgg aatgaacacg ccgatagagt ataacggaat caagcgttct gttgagccat
     7981 ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt gataatccca ttggaatagc
     8041 ctagtcgatc cccacgatct tgatacatgt gaggcatgaa tttatctttt gccagattgt
     8101 atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg
     8161 tagcaaattg aaggacgtaa tacaaaatac catgtccaaa gacagcttta ccaatttgag
     8221 acaaaacagt gacttctttt tcaggaacga tcccatacca atagttgata aatgtgatcc
     8281 ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg
     8341 ctcttggctt cttaaagaat ggtacagcat tactaatcgc ctccacccca gttaaagagg
     8401 aagaaccaga agaaaatgct cgtaaaatca aagcgataga aacacccggc acagccgctc
     8461 ctggaagtgc agtagcttgc aatggcacag cacctgtcac gatattatat aaaccaacaa
     8521 cgatcagtaa cgagatcaca aggataaatg tgtacaccgg aaataatagg aacgatgcag
     8581 attccctcag cccacgaaga ttcagcatca tcagtagcaa aacgattgtc acagaaatag
     8641 cgacttgatg accgtagagt gctggcaccg ctgatgtgat cgcttcagca cctgctgaga
     8701 cagatactgc tactgtcaac atgtagtcga tcaataaaga gccaccggaa atcaagccag
     8761 cattctttcc aagattctca ctgctgacga catatgctcc cccgccatga ggataagcat
     8821 ggatgatttg acgatatgat agcgttaatg aaatcaataa aataataaca aaagcggcaa
     8881 tgggtagcga ataccagatg gctgcagcag acaaagcgac taaaacgaca acgatttgtt
     8941 ccgtaccata tgcaatagat gataacgcat cagacgacaa taatgccaaa gcagcaaatc
     9001 gggttaattt gtgctcatca ttttcagcag attttaaagg cttacctact aacaaccttt
     9061 ttaagtaatc caatttctaa actcctttac acacaatttt acttcaagtt ttatagtcga
     9121 aaatttatag taaacaagat gttatagtac gctcactgac cttaaaagtc aataaacttt
     9181 aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct ttttcaaacg ctttaataca
     9241 gcaaaaatct aacatttttt tatgggcttt ttctttgaat tctataataa aaggatagaa
     9301 cttgacttag aaaatcaagt tctatccttt ttgatatctt aacttttgga agagagatgt
     9361 aaggctgctt tctacccatc attcttacta ctcgaagcat agcgcagttg tcacaacctc
     9421 ttgataaacg gtgtttaaaa gcttgcatct gcggtaataa gcccaaccaa attaaaaaca
     9481 taagaagctg tttttatttg gtcgttctta ttacttgatg cagagcagct tttttacaac
     9541 ctcttggtac acggtgttca atcagctgac cctcggtatt agctcaaaaa aacggcaaaa
     9601 tatgaggaac tatttttcca tttttttctc taatactcag gtcaaaacac tgatttcaca
     9661 acctcttttt ttaatgaaaa atatggctct catgcgccgc ttctttgaat ttcgtcattt
     9721 tttcttcgat gaacggatag attgccgttc ctacgattcc aaagacaaca aacaaaccga
     9781 tcatgatcca gattgctttc gtagcatttg gccaataaat tcctcctgca gattcccgta
     9841 acaagtttac cgcatgagta aatggcaaga acggattgat catttggaag aatttccctg
     9901 agacttggat cggatagttc ccgcctccgc cagagatcga cagtactaag atgataatag
     9961 cgatcccttt accgacatta tcgaataatg cagccaagac atagacgatc atcatgaacg
    10021 ctaaggcgat caagacagca aatgacacgc tgtagaccgg attttggaca tctactccta
    10081 gtaagaaaat attccctaat gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg
    10141 tcagcatacg agcaacgaat tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta
    10201 aatagtattc tgtcgtagca acacttgaaa gaagaacagc gccgacccac agacatagtg
    10261 cagtataaaa cggggtgcta gctgaaccgt tatttgcgat tggataaagc gcattggttt
    10321 gtagctcaac aggttgtgta aagaagtcac tttcttttgt tgcgtctagt ttcaataatt
    10381 tgatgacttc gcctagatcg acttcttgtt cgccttttcg gatcgcgtct gctgcttttt
    10441 ggataccagc tttgatattt ggccagtcat tgttgatcaa gtccgcagca gcgttcacag
    10501 ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa tgtaccggtg atttcatttt
    10561 ttagtgctgg ccaatcattt tggataaaat cagcggccaa tcctaatttt tgctgaatga
    10621 tcggtaattc attgttgtat aggtctgccc cttcattgat gccattgacg atggtatcca
    10681 tatttccatt cagcattgta ttggcatcat ggatttcttg tccaattgca ggcatttctt
    10741 tttgatattt ttctaaaatt gccactgcat tcgttacagt tgctttcgtt gagctgagaa
    10801 gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat
    10861 cgatgacttg gtctagtaga gaagtgacag tggaactgat ttgacctgta ttgataccag
    10921 caatgatgcc attgatatta ttaacaacgg catcaatttg atctagcaat tcatcaatag
    10981 ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga taggcggttt tgcagattgc
    11041 ttagcaaggg ttttaattga tttagctgat caataattgg ctgtaatttc gtatttccag
    11101 cacttgtttg caatttagtc aggaactcga ccagtttatc gattgcattt tgttgttgag
    11161 atattccgtc aataaagccg ttcaatacat tgctgatgtt tttcttttca tcatcagtca
    11221 gcttaccatc ttcaatagct gttcttacag tatctattaa cgaacctgtc gttgttgcca
    11281 cttgtccaat tgacttcaat gtaacatcta cactgtttgt gatgcttggt atcgcatctt
    11341 tcagctgaga ggcacctgat tttgtttggt ttgctagatc acttgcctga ttttctaaat
    11401 ttttcacatc tggcaagata tcttgtactt gttggatgat cgtcaagcct tgttttgctt
    11461 catcgattcc ttggttcatt gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta
    11521 gttgcttacc ggcattttgg atctctggga ttttttcttg caaatcaagg atgatttttg
    11581 cttgatcttt caactcaggc attttgtcat tcaatgcaac gactttttca cccatctcat
    11641 ctactttagg gatgtaatcc acgaattcat ttgctttatt cagtttttcc ttgatttcag
    11701 gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt
    11761 catctgttga taaaatcata tctttaactt tattgatact tactaggttc gtatcgatgt
    11821 cgtaacctat ctcattgaat actttcaata aagtcgaact ggctgttttg ataaattcat
    11881 ttgtgatttg cgattggatc gaacttgctc ctttatcggt gattttcggt gcaatcgcat
    11941 tgattttttc atttaccgta tattcgattt ttggtttctt gatatcacca ctagtaaaac
    12001 tcagcagatc ttctgagaaa tcctttggca agtaaatacc tgcgtaatac tttccggaac
    12061 ggactccgtc ttctaattgt tcttttgaat caacgaattg ccatcctaat tgtttatttt
    12121 tatgaagcga ttcgatgact tgctccccaa tggccacttc tttaccttga aactctgctg
    12181 gcttgtctgc actgtaaaca gcaattggca gctctccagt atttccatat ggatcccata
    12241 atgctttgat gttaaaccac gcatatagcg aagggatgat catgatcgcg atgatcagaa
    12301 gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag caaatataat cgaagcgtat
    12361 ttttgattga ctgcatagtt ctcccccttc ttcttttttc agctgaatta ctttaccatg
    12421 tatttcatac ttttttcaat cggctttttt caaaaaagtc gaatttttgg acatatcacg
    12481 gcaattgtct cattgtaatc tcttacatat tgagaaataa ttaaggatta cagcctttac
    12541 tttatcatga aataaaaggg aaagataatt ttatgccaaa gtttttatct attatacgta
    12601 tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac aaaaatgttt cagctttttt
    12661 cgttttttat tcctgtattt cttatttttc gaatgacagg atgattttcc cagcaggagg
    12721 atgtccttca actagctgat gtgcttggat gacatgctta agtgaagcag acagattcat
    12781 tgaaataaaa acatgaaagg ctcctttttg gtaggctttg attatgccag caaaggcttc
    12841 tgcatctaga tattcctttc ttggaacaaa cgattcataa aagccttcct ttttttgccg
    12901 caaatctaga tctgggaggt catttaatgc aacatacctg ccgcctggtt tcatgatctg
    12961 gatgccggtt tctcctttga tacttccttt cgtcgcatcg attacaaggt ctgcctgatc
    13021 agcaaattgc agacctggat ttgttttatc ataagcagca aatgctgaag ctcctaattt
    13081 ttttaccttt tcctcatttt tactggatgc actggttaag attcggattc ccttttcatg
    13141 gagaagctgg atcagacttg acccgaccgc acctgatgct cctagtatca ttacagtatc
    13201 tgtcggctgg atttccgtca aatggttgat tagattataa gccgtaattc ctggcgtgac
    13261 cattccggct gcttcttccc aactcatttt atctggaatt tttgctactt ttgctgatgg
    13321 caacacgact tcttctccgt aagtcccgcc gactgcatgg acagctactc gatcacctac
    13381 atgaacagtt gtgacatctg aaccaatctc tgtcacaata ccagcgccat cattacctgg
    13441 tacataaggg aatttcaatg ttcgtatctc tttcatttct cctaaacgca aggcaacatc
    13501 ataaggattc acactgaatg cttttatttc tacacgaaca tgtccagaac cgacttctct
    13561 gggatgagca tcgatttctt caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa
    13621 tcttcgcatg gtcaccatct ccctttttct ttaagtttac gtttatgcct ttattttgac
    13681 aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca aaatagttgt cttttttcgc
    13741 gtaacgtgtt aaattattta tctaaaagcg taaagattac gatttacgct aataaaaaat
    13801 aattggagga atttgttgat ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa
    13861 gaaacgattg aacgctatgc tgctttacgc caggaattaa aagcgcaaaa agattacgaa
    13921 ggcttgcgta aacttccttt agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc
    13981 gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa
    14041 ttagcacata aaggtttgat tccaggagta aaaaaagcca gctggtaatc caagtctggc
    14101 tgtaatgtaa aggaggaggg cgcatggacc actccttgga tcatcaaaaa agatacgttc
    14161 gcttcttcta gcagaaatgc tggtactaga agcagacgta tcttttttta cgcacagctg
    14221 gtcctttttt atatgtaaag gctgcatggt tacttcgcta tatttattta gtaacaggag
    14281 tcagtgcttc gatacccaca ctaattttca atgctcggtc aacttctgcc ataatgggtc
    14341 gatccaaatg gcagaccttt tctttcaatc ttgatttatc gatcgttctg atctgctcca
    14401 acaggataac ggagtctctt tctattcctg ttccagtagc tttgatccca atgtgagtcg
    14461 gaagcttagg tttagccatt tttgccgtta tggccgcaac aatgatcgtc gggctaaaat
    14521 ggttacctag attattttga ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca
    14581 cgactggaga aagatcagca aaataaatat ctcctctttt taccatagga tcctccttat
    14641 tcttgatatt ctcttggtat ccgctgtcct aatccgcaag ccacttcata gtggatcgta
    14701 cctaattgat ctgctatatc ctgcatagtg atttctttgt ctgcattttt gccgataagc
    14761 gtcacttttg ttccgacagg aaattcttga ggcaatcgga tcatcagttg atccatacat
    14821 acacgcccaa tcgtttcaca gtagttccct tctaccaata gagaaaaacc ctgcatcttt
    14881 cgtggccagc catctgcata accgatcggt atcgttccga tccactctgc ttcaggagtg
    14941 atatatgttt ctccatagcc gattccttca cctgctggga gttttttgac ttgaatcaat
    15001 tcagaaacca gctcaagtgc tggctgcaat ggataaactt ccggtagtgc gtgcccagag
    15061 ggattaagtc cgtacattgc tactccataa cgaatcatat tgccgattgt ttcatcatgc
    15121 cataaagccg ttgcactatt gctgacatgt acatatcgag gaagttcggg aagttttttc
    15181 agcacttcta taaagcgttc tttttgcaga ttccaatatg tatcatctgc ctgatctgct
    15241 gtagaaaaat gggtaaataa accttcccat tctaatacac gactttcttt gatgaatgca
    15301 gctgcctctt ttacttcttc aggtgtacaa aatccgatac gacccatccc agtgtctgct
    15361 tttagatgaa tcgaaagagg cgtctctagc ttacttttct ctaaaacagc agctgctgct
    15421 tgcaaccatt cccgtgtacc tgcagttact gataaatcat gagcaacagc tacagtcagt
    15481 gcgtcgtaag gaaccatatt caagataagg atgggctgag taaatccagc ttctctcaac
    15541 tcgactcctt catctaaatt tgaaacacaa aagcccgaag ctccacctgc aactgctgcc
    15601 tcagctgttt caatagctcc atgaccgtat ccgttcgctt ttactactgc aaacaattct
    15661 tttccttgcg gaagtcttgc aacttcattt gctacatttt cagttatagc ttttttatgt
    15721 atcactgctt tcgttgggcg gtgccaagcg acaaccatcg tttttccttc tttctagtct
    15781 tccaaaataa tttgtgcaaa agctgtttca tttgtatgag taatactgac ccatacattg
    15841 ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt cattttttaa aatctcgaca
    15901 tcttgaaagg taacttttcc gatcccagtt ccccaagctt tagagaaagc ctctttgcaa
    15961 gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag gcaaggactg gaatagtttc
    16021 atttcatcag aggtcaagat tcgtgcaatg aattttggtt tttcttcgat cagccgagtg
    16081 atcctaggaa gttcgactgc atcgatccca attcctttta tcatatgctt ttctcttttc
    16141 aataaattta gaacactctc attctaccaa attataacca ttttgccaca aataagtcca
    16201 caaataacaa aaatgaaagt ttctcttaaa aaagagaaac tttcatttta tgtttaatcg
    16261 ttatttgaac ggattacaaa tccgcgtttt ttatcattgt gacgtttacc gccatctttt
    16321 tggctgttat tatttttgct ataaccgcct tttgatttgt ttccacgata attaccgccg
    16381 tcacgacgat tacggttgtt tccgccacca cgtttgccat ttttattgta tccttttttc
    16441 tgcattggca atgggcgttc tggtgtgatc ttcactggca ctgcatcagc tggatctttt
    16501 gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag aatattcttc taataattta
    16561 tctgctgttt gcaggtattt atctagacca ttttctgcaa gttttgtttc gatttgttca
    16621 actgcagcac ctaattgacc tttgaatgct tctttttcgg ttggtggacg taaagtcgtc
    16681 atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg
    16741 aaagtcacag acataccgcc ttttccggca cggcctgtac gtccgatacg gtgaacgtag
    16801 ctttctggat cttgagggat atcatagttg tacacatgag tgacacctga aatatctaat
    16861 ccacgtgcag caacgtctgt cgctacaagg atatctaaat gaccgctctt aaatgaacgc
    16921 aatacgctca ttcgtttttg ttgagacaaa tcgccatgga ttccttctgc acggtaaccg
    16981 cgtgcttcta atccgcgtgc caattcgtct acacggcgtt ttgtacgtcc gaagacgatt
    17041 gttaattcag gtgtttgaac atcaaacaag cgagtcatga tatcgaattt ttcgtattct
    17101 tttgcgcgga catagtattg atcgatcaag tcagctgtca tttctttcgc tttgatcttc
    17161 acatgatgtg gatttttcat gaatttaacg ccaatattct tgatagctgg cggcatcgtt
    17221 gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg aaatgatttt ttcgatatct
    17281 tccaagaagc ccatattcaa catttcatct gcttcatcca aaactaatgt ttgaacggtt
    17341 ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac gtcctggtgt acccacaacg
    17401 atatgtggac gatctttcaa gccacggatc tgacggccaa tatctgctcc gccgtaaacg
    17461 gcttgtacac gtactttttt gtcgcgccct aaacgatata attcttcttg tgtttggata
    17521 gctaattcac gtgttggtgc gataactaaa ccttgtaatt cgtgacgatc tggatcgatt
    17581 ttttctaaca ttggtaatcc aaatgcagct gttttccctg tacctgtctg tgcttgtcca
    17641 ataacgtctt ttccagctaa tgctagtgga atcgtttctg cttggatagg cgttgcttct
    17701 tcaaaaccag cgcgttcgac tgatttcaac aattctggtg ataattctag ttctttaaat
    17761 ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt agcttttttg ctaccccgtc
    17821 gatttgttcg gtcaaagtgt attgtttctt tttgacagtg gccacgcacg tttttatcca
    17881 ttcttagccc ctgtggcacc accgaaaaat cactttgcga agtttaggca ttagaaaagc
    17941 caaacgggtc gcgttcagct ttatcattat tatgacatct ggcttcaaca agttgtttct
    18001 atggcaaaac cagtccaatt tctcttcatc tttcggcaat aggttattct aacatagttt
    18061 ttcgttttct gcaagtttac agatttttat ttcatttgct gaagttgttc taccacttca
    18121 aataagccca tgctgttgct gccttttagc ataatactat ctgttgcttc aagattttgt
    18181 ttgatagcat caatcaattt attcttttct ttttccaaat agaacacagg tagttggggg
    18241 tatttttggt tcaattcttc ttttagtgca tgcatttgtt ccccataaag gaaaatcatg
    18301 gcgaatttct caggatcgat atgttcactc atttgcgcat gcatatttaa agactctttc
    18361 cctaattcca gcatatctgc taacacagcg attctgcgtc cttttgttgg cagattttta
    18421 aaagtatcta ataccagtcc catggctgtt ggatttgcat tgtagacatc gctcaaaata
    18481 gctgcaccat ttcctgccgt tagccattcg gttctgtttt gagtgataga aacatgggcg
    18541 agcccttggc gtatctcagg tatggacagt ccaaagaagc gcccgatcgt atacgcaatc
    18601 aaagcattcg ttacattata acttccaggc agcgggatcg taaatgtttc tccttctact
    18661 acaaaatcgg tttgtgcttt tccttttgct gtcacttccg catgaacatc gccatttcca
    18721 ataccgaatg ttgtgactgt ttgtactaat gttgccgtta aaggtgtcag caacggttca
    18781 tctgcgggca caacgagtaa tccgtctgat acaagtccgt cagtgatttc cattttggct
    18841 ttagcgattc cttctcgcga cccaagattt tctatgtgtg cttcaccgat cattgtgatt
    18901 gctgcagctt ttggttgagc cataagtgaa agttccgtga tttcattggc gtgatccatg
    18961 cccatttcca aaacgatctt ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga
    19021 ccaatattat tgttgtaatt tccttgcgtc ttatatgttt tgtatttttc agacaagaca
    19081 gacgcggtta gatctttcgt ggtggtttta ccattgcttc ctgtaattgc aacgacttct
    19141 gcgcctactt tttccaagta ataggttgcc aattgctgca tggctttcaa aggatctgct
    19201 acaggaataa ctggaaaatt ttttggagct tgttcaacag gcaagctcca aaatgaagca
    19261 gatgctccgt ttgtgatcgc ttgctggata aattcatgtc catctcgcgt accagcaaga
    19321 ggaacgaata aacttccttc ggttatcttc cggctgtcaa attcgacatt ggtaatcttt
    19381 gtcagtgcag agcattcgct gcccacggct tgtgcaattt cttgtattgt tagattcatt
    19441 gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg
    19501 actctcactt ccaagtaaat ttctctattc gtatttagaa gctagaatga acgcggttac
    19561 gcaatcactc cagcctcttc tttatttctc tttattcatt tttttcaaaa aaagattgac
    19621 gctgatggta tcgattcatt cctaactgga tcagttcttc aatcaaatca ccgtatttca
    19681 agcccatatt ttcccataag agtgggtaca tactgaactc cgtaaatcct ggcatagagt
    19741 ttaattcatt caggaataat tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc
    19801 cgcttccacc taacatcgtg taagctaact tcgcgtactc ttgcgctttt tgataaactt
    19861 cttctggcac ttcggctgga atctgcattt cgattttatt attgatatat tttgcttcat
    19921 aatcatagaa tgctacgtct tttacgactt caccaggcaa agtcgtccga acgtcttcat
    19981 ttcctaatac agcaacttcg atttcgcgcg cttcaattcc ttgttcaacg attgctcgag
    20041 aatcatactg ataggctgtt gctaaagcat tttgcagctc ttctcggttt tctgcttttg
    20101 taatgccgac actagaaccc atattcgccg gtttgacaaa catcggataa agcaaagaac
    20161 cttcacattg atcaaatact tttttaggat tttctttcca ttgattctta agtactggta
    20221 cataaggaac ttgcggcaca ccagcagctt gtaaaatata cttggtcatg attttatcca
    20281 tggcacatgc actggtcaat acgcctgcgc cgacataagg catattcaat gtctctaaga
    20341 agccttggat cgttccatct tccccgtttg gcccatgtaa aactggaaaa acgatggctc
    20401 cttcttcttt gatttcgccc ggattgatca cttttcctgt aaagccttcc tctgtctgtc
    20461 cacttgggtc ccatgaaaga tgcaagacat ctttgctggc aggtttttct gttagtaatg
    20521 gacctttgac ccattgtcct tcttttgtaa taaatacgag ttgaacttgg taataattat
    20581 aataaatggc atttaaaact gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc
    20641 gtccgccata tagtaaagta atcttcaaaa gattgtcctc ctgtattcta aatcgttcag
    20701 tgatttactc tcatatttta gcacaaaaca aaaataaacg aataacttat ttataaaaaa
    20761 acgagccagc ttctaaaaga acgagcgtca tttatttttt gtcagctaga ttatttgtcc
    20821 cgttttttat aaaaagttat gataaagaaa aggagggatg atgatggcgc aaacaaatcc
    20881 acgcagccgc ttggcagaaa tcattcgagt gttcatcaat tacaatgtag tgccaaactt
    20941 tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt gaagaactag gccccacctt
    21001 catcaagata ggacagatgc tttctgttcg agaagatttg ctttcttctg ccttcactca
    21061 aacattcaaa acattacaag atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac
    21121 gatcgaaaca gaactttctc tttcattatc agatatattc gatgattttt caaaatcgcc
    21181 ttttgcctct gcttctatgg ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt
    21241 agtcgttaag atccaacacc ctaacatcgc cgaagagatc cgacttgatc ttcaactatt
    21301 tgaacgagcg atccctttga tcaaatacat tcctgaaact agcgtagttg atctaaaagg
    21361 ggtactccaa gaagtaaaac gttccttgat caatgaaatg gacttcttaa aagaaagtca
    21421 aaatggcgaa caattctatc aaaagaacaa tggctggaaa gagatccgca gccccaagat
    21481 ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt
    21541 gaatcattta atgaacgccg aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa
    21601 gcagctgaaa caagaagttg caaagctttt agttgagaac tttatgaaac aggtgtttga
    21661 tgatggtttt ttccatgctg atcctcatcc agggaatctg ctattccatg tactaacaaa
    21721 agaagaacag acacaagcta gccgaaaaac tgaaacagtc catgaaaaag agttcggttc
    21781 ctttgctttt cgagcctcca cttctgcaga agaccctgtt gcgccatata ccatcaacta
    21841 catcgatttt ggtatgatgg ggcatctttc tgcaggactt aggcaaaaac tcacacaagc
    21901 cgttttagcg ctgtatacga aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg
    21961 tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa gaactgacaa gttttcttga
    22021 acagtattat gattctccta ttgatgaaat caacttgcaa gaagtattca cacatgtcgt
    22081 gacgatttgt catcaaaata atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc
    22141 atttgggaca ttagaagggg tgatccgcgt cctcgatcct gaagtttccc tcatggaagt
    22201 cgcttcgcct tttgctcaac attattttct cactcatctg gatgtagaag atacattgaa
    22261 acaaagcgga ttagacttat tggaagggat gaaggctgcg cctaagatcc ctcaacagct
    22321 ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa
    22381 gcaagacaaa ttattgagca ggatcgaaag tatgatcaat cggcttgttt tcggtatgat
    22441 tttagctgca ttgatcgtag ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc
    22501 agaggtcgtt tccttattag ggatatttac gtatgctatt gccgcattcg tcattatttt
    22561 tttggcaatc gatgcattga tccaaatgta taagaagagg aaaaagtaga aaaaggttgt
    22621 gacagaaaga atcagcttca agaaataaga aggggtttta cataaattgt ttctcaaatt
    22681 tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct gaaacaccga gaataaaaaa
    22741 tgtgaaaaag ctgttctgca cccagtaata agaacaatca aaaagggaac atggaacaca
    22801 tttatcctgt ttccctgttc cctttttgat gtattcgagc ataaataaaa taccttcgtt
    22861 acctactatc ttctgtactt ggtaaacctt agtcaattgc cttttttaac gcttgacgaa
    22921 aagacatatg atctttctcc gtaaagggtt ttggaccctt tgtccttatg ccagcttttc
    22981 ttaactttcc actatgataa cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt
    23041 cttttccaga gtgatggaac actcgcacac ccttcggcaa tacaagtgaa gctaaaccat
    23101 aatcttgcgt gatcaaaaag tcattcttct taaccatacc gacgatttta taatccgcac
    23161 tatcagctcc gcggtctacg tagacgattt ggacatgatt agcgtattct ttggtcgtat
    23221 aatggtccac actggtcacg ataaccacgt caagaccata ggattctcct aattttatga
    23281 catcttcttt tactggagaa ccatctccat caatgaatag cctcattctt tttcgccttc
    23341 ttccataaat gataaacagt tactaatccg ctcagtaaaa gaccaacatt gatccatttt
    23401 gccaagataa gcagttgtac actttctatc ggcactgatt catggttcag cgtgatcaat
    23461 aatagatgga ttggctctcc catttctttt gctaaaacaa acaaaagcgt catcaataaa
    23521 aactggtgga tcacactccc tttattttga gtagtatact tgacaacgat ccggcgatcc
    23581 attggaatag ctgtatcagt ttgataatat tccttattta gccagctgcc tgttactacg
    23641 tgccagaaac taagcagaaa gacacctatc gcaaaaccat ttggaatcaa gaggaccaat
    23701 aaagaagaac tcagtccaag caattgcata gccaatggag accatgttaa acgtttcaaa
    23761 atccatggtc cgactatttt tgctgcaatc aagcctgctg cataaggcaa atacataaaa
    23821 atcgaaagtt tttctaatcc gtacagtatg ccaacataaa aactgctaaa taaaaaaagg
    23881 aaattcccta gcattccatt tagaaaagta aacagattta gccagcttgg caacttccat
    23941 tccttcttct ggtgtcctaa aacaaacacg aacaagatga acagcagcaa gaaaccataa
    24001 atagcaagat caaaaagcct ttcatcgaat aacaatcggg catttctcaa aagaaacaat
    24061 aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag ctaccagatt tcttttgatg
    24121 tctttgaaat ccagttcgta acgcggataa tgactaaccg tatggtaggc catgacgtaa
    24181 aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct
    24241 tgatacagga gaaatagcca gatagctgca aataagtact ttttcccatc catattgata
    24301 aaaccttgcg tcttttcgtg aaaattgacc gtggtattag caggtacaag ccatgctgca
    24361 ctcagcccta gcaaaacact tgaaaaataa aataaaggaa aataaaatac gcctaatatt
    24421 ccaagcaatg aaccagcacc accaatcagc agagcgatca tcagcaacgt gtaactatct
    24481 agaccaaatc gtagactgtt gactaaaaat agtccagtca tccgaaaggc ataaaacagc
    24541 gtaaatggca aaatcgtcag ccaattatgc gagtctgtta gtcccaaaaa taaaagataa
    24601 ggaataaaaa taaccgtgtt acttaagata aagggcgttg tttgtgtaaa attacgccca
    24661 aatcgtttga gtttttcgaa catgacaatg gctccttaaa cagtcttata actaatctgc
    24721 tcttcgattt tagcattaaa ggggaaataa accaatttta cagaatatat tcttgtaaaa
    24781 aaaaatacag aaagaagcat aagcttcttt ctgcattttt acggtacttg attactcaag
    24841 cagacaagcc cttctccaca aaagtcttgc ccgacacccc tgcatccggc aggtgataaa
    24901 gatagaaatc aattatcctg tgcctccaaa atcaattagg agctctgtaa accagagtcc
    24961 ttctcgaccc gtcgcataaa tttactttaa cacagttcct atgtttatgc gagagctttt
    25021 ttcattttat aatcgaccat ttgaaatcct tgaccgatat ctgaaataag ttcttctgta
    25081 atctcaaatc cttcatgctt ataaacctcg attgcttgat gattcccctg attcactcgc
    25141 aaaaagatct ctctttcctt tgtttgcgca gcaagttctt cataccagcg aaaaactgaa
    25201 gaagtcaatc cttgaccacg tactttattt agcaaatata atttacttaa ataaattttt
    25261 ccatttatct cttcataagc agtgtaaccg acagtctttt cttcgctttt taataaaaag
    25321 taggacacac cttctgtcag ttctttttga atctgttttt ttgactgata agttttcagc
    25381 atgtaatcca cttgtttttg accaatgatc ggcacaaaag cttccggcca tacttcttgt
    25441 atgactgcca tcagctcatc cagttcattt tctgttactt ttattttttc catacaccca
    25501 cgtccttttt tacattataa atgaccttgc gcttgatgga ataaaaagag catgatcatg
    25561 ctatacacac ccaccgacca tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa
    25621 gataatttcg tcaaaccagc tactagacag atcaagtcgt ctggcgcaaa gggaagcagc
    25681 aaggtaacaa ctagtacttt tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat
    25741 ttctgatact tttttggcga taaaataagc tggacaaagg ctacgccata gtaacggaca
    25801 agcaaaaatc cgattgcttc cccaatcact aggccaatac aactatataa aagcccaaat
    25861 ccattgccaa acatcagcat gcccgctact gaggagatcc ctcccggcaa aataggaatg
    25921 atcacttgga tcacttgcaa cagaacaaat atcatcactg catacttgcc aaattgctgg
    25981 ataaacgctt gcaaagacgt gctcgatcga aaaatcccat gatgataagc ataaagaatc
    26041 aacacaaaga aaaaaaacag accaataatg ggcatgatct gaagacattt ttgtaaaact
    26101 gatccttttt tagacatcta tattccccac atcttttttc atttattaaa actgcctcct
//
LOCUS       DAIGSZ010000041        25035 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.041, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000041 DAIGSZ010000000
VERSION     DAIGSZ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.041"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            5..1558
                     /locus_tag="NOB31_001761"
                     /pseudo
     CDS             5..1558
                     /locus_tag="NOB31_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(1666..2748)
                     /gene="uxuA"
                     /locus_tag="NOB31_001762"
     CDS             complement(1666..2748)
                     /gene="uxuA"
                     /locus_tag="NOB31_001762"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCI0973969.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(2739..4385)
                     /locus_tag="NOB31_001763"
     CDS             complement(2739..4385)
                     /locus_tag="NOB31_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HCI0973970.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            4569..5231
                     /locus_tag="NOB31_001764"
     CDS             4569..5231
                     /locus_tag="NOB31_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0973971.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            5375..5938
                     /gene="ahpC"
                     /locus_tag="NOB31_001765"
     CDS             5375..5938
                     /gene="ahpC"
                     /locus_tag="NOB31_001765"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HCI0973972.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            5948..7477
                     /gene="ahpF"
                     /locus_tag="NOB31_001766"
     CDS             5948..7477
                     /gene="ahpF"
                     /locus_tag="NOB31_001766"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HCI0973973.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     RTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            7634..7984
                     /locus_tag="NOB31_001767"
     CDS             7634..7984
                     /locus_tag="NOB31_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HCI0973974.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            8083..8613
                     /locus_tag="NOB31_001768"
     CDS             8083..8613
                     /locus_tag="NOB31_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCI0973975.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            8767..9918
                     /locus_tag="NOB31_001769"
     CDS             8767..9918
                     /locus_tag="NOB31_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HCI0973976.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(10027..12066)
                     /locus_tag="NOB31_001770"
     CDS             complement(10027..12066)
                     /locus_tag="NOB31_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HCI0973977.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGAIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(12124..12681)
                     /locus_tag="NOB31_001771"
                     /pseudo
     CDS             complement(12124..12681)
                     /locus_tag="NOB31_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            complement(13220..13426)
                     /locus_tag="NOB31_001772"
     CDS             complement(13220..13426)
                     /locus_tag="NOB31_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973978.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(13442..14056)
                     /locus_tag="NOB31_001773"
     CDS             complement(13442..14056)
                     /locus_tag="NOB31_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HCI0973979.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(14203..14886)
                     /locus_tag="NOB31_001774"
     CDS             complement(14203..14886)
                     /locus_tag="NOB31_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCI0973980.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(14995..15453)
                     /locus_tag="NOB31_001775"
     CDS             complement(14995..15453)
                     /locus_tag="NOB31_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HCI0973981.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(15537..17300)
                     /locus_tag="NOB31_001776"
     CDS             complement(15537..17300)
                     /locus_tag="NOB31_001776"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HCI0973982.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(17521..18981)
                     /locus_tag="NOB31_001777"
     CDS             complement(17521..18981)
                     /locus_tag="NOB31_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973983.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(19189..20115)
                     /gene="glsA"
                     /locus_tag="NOB31_001778"
     CDS             complement(19189..20115)
                     /gene="glsA"
                     /locus_tag="NOB31_001778"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HCI0973984.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(20138..21565)
                     /locus_tag="NOB31_001779"
     CDS             complement(20138..21565)
                     /locus_tag="NOB31_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0973985.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(21596..22810)
                     /locus_tag="NOB31_001780"
     CDS             complement(21596..22810)
                     /locus_tag="NOB31_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HCI0973986.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(23151..23393)
                     /locus_tag="NOB31_001781"
     CDS             complement(23151..23393)
                     /locus_tag="NOB31_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0973987.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(23425..23982)
                     /locus_tag="NOB31_001782"
     CDS             complement(23425..23982)
                     /locus_tag="NOB31_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCI0973988.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(23995..24183)
                     /locus_tag="NOB31_001783"
     CDS             complement(23995..24183)
                     /locus_tag="NOB31_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCI0973989.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(24196..24762)
                     /gene="amaP"
                     /locus_tag="NOB31_001784"
     CDS             complement(24196..24762)
                     /gene="amaP"
                     /locus_tag="NOB31_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCI0973990.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         7391 a         4895 c         4344 g         8405 t
ORIGIN      
        1 tttcatgcaa actcaagaag cgattaaaac gtttatcttg aagaaaaaaa gcaatacaaa
       61 attagatatt tttcttttcc tatctgaaca tcgtttcttt attactacac aatatttagc
      121 agatcatttc catatgtctg aatcaaattt tttactatac atcaaagaat tagaacaaga
      181 ctttgagcgt ctcaatctaa cagaactgca tattgataag caaaaacctt ttttaaagtt
      241 gaattttgaa ggaattgatc cggcttactg ctattatcgt ctatttggaa gatactgcaa
      301 cgaatcagtc agttatcaga tcttgacttc tttgttcagc tgtcagacaa attcgattat
      361 cagtttcagt cagcaaacaa actatagtgc ctcttatttg tatacgaaaa tgaaaaagat
      421 taatgcattt ttagcatagt acggtttgtc tatctccttt tctaataatg gcagaaagtc
      481 tttttctgga aaagaggtac aaattcaata tgcagcatta gatatttatt ggaacatctt
      541 ttcaagtact gctacagaat tttatgatga agatccgcaa gtagtggctt ttatgatgaa
      601 tacttttttt aaaaaagaag tacttgaccg actaaatagc ggtatgatag ataaattata
      661 ttttctatta aaaatatgta aagagaattt tcctgcaact tctgtgaaag acgtacaaaa
      721 agaattcaca gagtatgaat atattgactt ttttattgat ctctctgtag atattttgcg
      781 acctaatctg ccaatttgtc gcgaacaacg catcttagtg aatattttag ctcgactttc
      841 tatcacgaaa atcgaatcgg aagaaacaag cttggagcaa tacaaacttt taaaaaaagc
      901 aaacgttcct catgttcttt attcaagaga aatggtggag tccctttgta ctgtatttga
      961 tttgtttata cctgaaaaag aaaagattct ttactcattg gcattcgcac gaaataaact
     1021 ttataatgga tttcttaact tcaatcaacc aaatacgccc cttcctactt tcatgcttta
     1081 tcaagaacat agcgtattga aagaagtcca aaccgccatt gaacaatttt atatggattt
     1141 cagagaacaa aatcaacact tgttaccagt tattttagaa aaggaaaatg tgcaatggat
     1201 ggttgaagac ctagtacatt tgtatgatcg ctacaaaaaa cagccgcgaa ttgtgattgg
     1261 tgtgaactat acgcgtgatt tttatatcag taaagatctg atcgttaaga tagaacaaat
     1321 tttttcaaat gaatcgatca aaatacaaaa tgattttatg gagaactgca acatcgttat
     1381 cagcgactgc cctttgaaac aattgccttc tcatatcaaa aaaatctata ttttaaaagg
     1441 aatcatcaca ccagaagact ggaaaaaagt gattatgagg atctcagaat atatctttga
     1501 attaaaagaa gaagcactca tggatcaatc gaaaaaagaa aatcaagtta cttcctagac
     1561 caaataagat acataaatcc gaatgcttat taacaacctc cggatttatg tatcaagaat
     1621 ttgaacatcc ttcttattta cataataaaa ttacagtttt tttcactaat tatctttact
     1681 tttgtttcct ttttcgattg cttcccataa tccatttaga taaacagcac ctaatgctcg
     1741 atcatataag ccgtatcctg gtcttcctgt ctcattccag atcattcttc catgatcagg
     1801 acggatgtat ccgttaaatc cgttgtcata cattgttttt agtatgcggt acatgtctaa
     1861 tgaaccgtat tcggatttat gtggtgcctc atagaaatct cgattagcta aaaatttaat
     1921 atttcgaaca tgtgcaaatg ggattcgatc tctttggcaa aattctgcta aaatcccata
     1981 tacatcattt tctggatctt ctgcaatact ccctgtacaa agagtgattc cgttataagg
     2041 gctgtctact atgcgacaca accaatctaa atcttctcga ttctttacga ttcgagctaa
     2101 tccaaaaatc gagtatggcg gatcatctgg atgtacagcc attttgaccc ctacctcttc
     2161 acatgttggg atgattgatt ggagaaaata ggcaaaattt tctcgaagtt tttcttcgtc
     2221 tactgatgca taggcttcaa gcaaggattt gataggagct aagcgctcag gttcccatcc
     2281 cggcaatcca aattcattgc tggaatgttc gatgcgcgcg acgatttctc ttggatcatc
     2341 tggaatatca tcagatataa aagctaacgt ggatgagccg tcttctaagc ggtagtcaag
     2401 gtcagatttc acccagtcaa atacaggcat aaaattatag cagatgactt ctattccata
     2461 ttctgccaag tttcggattg tctgcttata gttttcgata tactgctcac gggaaggtaa
     2521 tccaatttta atggcatcat gcacattgac gctttcaatt acttttagtg ttaacccacg
     2581 agactcaatt tcttctttta gttctttgat cctctcccta ggccatacct ctcctactgg
     2641 tatatccatc aatgtgccta caatcccttt gaccgcagga atctgtctga tttcatctaa
     2701 ggtaatcttt tcttcctgtg atccgtacca tctaaaagtc atttccatga taaatttcct
     2761 ccatgttctt gtaagtaatc ctgtaatgtt tttcgtacgg catttggtcc tgctaccatc
     2821 ttgatgaaca tttcttctat ttttctgcca agctctgctt ggtaaagatc tacaccaaaa
     2881 atttctttat ttgacaaaat aggagccatt ttctcatgaa tatgtgatgt atcttgcgta
     2941 cccagttgaa tatcggaaag cttatgctga aggtctgtca atagtgggtc tggactcggg
     3001 atgaatggtt ttccttgatc atcaatgcca ataaggtatc gaagccaagc agcgagagtc
     3061 aatggtatga atacaagtgt ctgcgggtct ttaacttcta tttccatata ttttttaatc
     3121 gtctcaccat aacgaatcgc caccttttga gaggtatccg tggcgattcg ctgaggcata
     3181 ttaggaatat ttggattaga aaagcgcaca gtaattactt cttccagaaa gatctttgga
     3241 tcaatgatac ctggagactc cacaactggg aggccttcat tgtacccgat ttcagaaact
     3301 agcagcgata aatctggatc tttcatctcc tcagctatgc tcctataccc cagtaaacaa
     3361 cccataatag ctaaagacgt atgcaaagga ttaaggcaag tcgtcacctt catcgtatct
     3421 gctttatcta ccgttgcacg atcagtcaag aataccccag ctttttcgaa tttcggacgt
     3481 ccattgggaa aatgatcttc catgattaaa taatggatgt cctctgtatt gacaaatgga
     3541 gcaatattat ttccttttgc ggtttggaaa atcgacatat ttgaaaagcc ctcttttgcc
     3601 aacattttgc taactgacaa ggaaggattc ggggtgatac gatcaatcat cgtccatgga
     3661 aacgcaacaa tttcttcatt cgataagtat tggataaatg tattttgtac ataaccttcc
     3721 ttttgccatt cttttgcgat cgttagcaaa gaagtacgta attgactacc gttttgtgaa
     3781 aaattatctg tagagacaag tgcaatcggc caagctccag ataaaaaacg tttataaagt
     3841 agcacagcaa gaatactcat tgtatgtgat ggcttctttg gaccattttt tatatcgact
     3901 gcaatcggtc ctatatattt attatttgta tctttcaatc gataaccttt ttcagtaata
     3961 gcaaaagtaa ctaattgtaa actaggattt tcaaagtgtc gaatcatctt atcaaagtgt
     4021 tcagaacaat ctggatgaca atacagactg tcagctgtcg cagctaatat acgtttgacg
     4081 aactctccac tgcttggcat gaccacttca agaatcaaat catcaaaatc ttggtaagcc
     4141 ctttcaatta tttcttcatc gaatgtttca caaacaatga caccagtgga caattcgcct
     4201 agatccgcta aacgttgagc gatttctgca tgaaatcctc gataaagatt tccgccaccg
     4261 aaatggatcc agacaggatt tttttgtcca ttttctctta atgatgcacg gtcaaaatga
     4321 ggtatttcta cttctttttg agataattca gggataaagt tcctccagtt gtttaaatca
     4381 atcatttttc ccctcctaaa ctaacatatt agtttttgta ttcaagtgaa ttttatgcaa
     4441 taaaaatcgc tatgtcaacc aaaattttac tatttataca aatttactag ttaatgtgac
     4501 ataccagatt gtttttcaga cctcttctgt tatactacgt tcatagaaat gattttggag
     4561 gaataaagat gaaaagcagc ttgcaatcac aagcttatca agcgattcgt aaacaaatta
     4621 tctatgctga cttagaacct ggaaggaaaa tatctgaaaa ggcactggag gaacatcttg
     4681 ctatcggccg gactcccatt cgcgaagcat tgattcaact acgtcagcaa gaactcgtgt
     4741 atacgatacc tcaaagtggt acgtatgttt ccaaaattaa tcttgtttct gcagaaaatg
     4801 ctcgctttgt ccgagaacag ttggaagagc aaatcatgat tgaatgttgt tccaaattgg
     4861 acacacaaac acgaatagtg ctagaaacga ttttagaaga acaagaaaaa gcagtcaaaa
     4921 taaatgacga acgcgctttt ttccgtgcag ataatttatt tcatgaagct tgtttcgaaa
     4981 ttgcaggaag aaaagaagtt tggaactggt tagatgacca taatacccat ttagaacgtt
     5041 tccgctggtt acgagtgacc attcaggggc ttccatggga aacgatcatg gaacaacatt
     5101 atgatttact caaggcttta gttgataaaa aaccagaaga agctcgattt caaacgggat
     5161 tgcacttaca catgatgctg aaagaacagg aaactgttac tcaacgttat cccgagtatt
     5221 tccagcagta gcattttctt gcgacctctt ctatttttat aattaacctt cgtttttgag
     5281 taatctttat taaataacaa aatatccatt gactttgcaa ctccaactaa attacaataa
     5341 ttataaataa ataattatta ttggaggttt tactatgtca ttgattggga aaaaaatcga
     5401 agaatttaat gcacatgctt atcatcaagg agaattttta gaagtcagtg aaaaagatct
     5461 tatggggaac tggagtattc tttgcttcta tccagctgat tttacttttg tttgtcctac
     5521 tgaattagaa gacttacaag aacaatacag tacattgaaa tctttaggtg ttgaagtctt
     5581 ttcttgctct accgataccc actttactca caaagcatgg catgatacat cagatgctat
     5641 cggtaaaatc gaatacgtga tgatcggtga tccgtctcat cagatttctc gtatttttga
     5701 tgttttggat gaagagcaag gattagctca gcgaggaaca tttattattg atccagacgg
     5761 aatcgttcaa gctatggaaa tcaatgcaga tggaatcggt cgtgacgcta gtgcactgat
     5821 tgataagatt cgcgctgctc aatatgtacg tacccaccca ggtgaagttt gtccggcaaa
     5881 atggaaagaa agtggcgaaa cattgaaacc aagttttgat cttgttggaa agatttaggt
     5941 ggtggatatg ttagacaaag aaactaaaca aaatctcgaa caatatttag cactgattga
     6001 atctcctatt gttttttctg ttagtttgga taatagtgaa aatagtcaaa aactagctga
     6061 atttacgaag gaaatagcag aaatgtctcc taaaatctct tgggaaaaaa gagattcgat
     6121 gcgcacacct agtttttcta tcaatccagt tggcaaagaa agtggaatcg tttttgctgg
     6181 tatccccctc ggtcatgaat tttcctcttt tttactggct atgttacaaa ttagtggacg
     6241 ggcaccgaaa atcagtgaat ctttgagtct taaaatcaaa aaaataacac aaacattgca
     6301 ttttgacagt tatgttagct tgacttgtca taattgcccc gacgttgtac aggcattgaa
     6361 tatattagct gtattaaatc caaatattac tcatacgatg attgaaggtg ggatgttcca
     6421 aaaagaaatc gatgataaaa aaatcatggc agtgccaact gtgtttttaa atggagaaga
     6481 atttagtagc ggacgcatga cgatcgaaca aattgttgaa aaaatcactg gccctttgat
     6541 tgaagaagag ttgtttgaaa aagaacctta tgatgtatta gtgattggcg gtggaccagc
     6601 agctagtagt gcagctatct atgcagcacg taaaggaatc cgtacaggac ttgtcgctga
     6661 ttctttcggc ggacaagtcg ttgaaacact agggattgaa aatatgattg gtacctctta
     6721 cacagaaggt ccaaaattga tgcagcaagt agaaagtcat gtgcgtagtt accctatcga
     6781 cattatgatg aatcaacagg ccgtttcctt aaataaagag caacatttta ttaatattgg
     6841 cttagctaac ggtatatcac ttaaagcaaa aaccgccatc atcgcgacag gtgcgcactg
     6901 gcgttctatc aatgtaccag gcgaaaaaga gtttaaaaat aaaggaattg cttattgccc
     6961 acactgtgac ggccctttat ttaaaggaaa agagattgct gttatcggtg gtggtaattc
     7021 tggtgttgaa gcagcaatcg atttggctgg gttagcaaaa catgtatatg ttctagaatt
     7081 cttaccagaa ttaaaagcag atcaaatctt acaggataaa ctagtctctc ttgcgaatgt
     7141 cactgttatc aaacatgcag cgacgaaaga aatcagcggt acgaatcagg tagaatctct
     7201 ctcctatatc gatcgccgta cgatggagat gcatacacta gctgtttcag gagtattcat
     7261 tctagtcggc ttactcccta atacggattg gctagataga acgatcgaaa tgaatccaag
     7321 aaatgaaata gtgaccgaga aaaatggcgc aacgaatatc cccggcgttt tcgcagctgg
     7381 tgattgtaca gatagtccat acaaacaaat cattgtttca atgggttcag gagctactgc
     7441 agctttagga gcattcgatt atctgatgcg cacttgagct atgaagattg taaaaagtca
     7501 gagagcggaa aaaaggatgg tgacaagaat tttgtcacaa tcctttttgt ttttttgaat
     7561 aatcgctttt tcttctcttt ttcttatata ctataagtag taaataattt gaaaaaaaga
     7621 aaggtgactg attatggcgc aaaatcgtat ttttacgaca agttttgcaa gcgtttatcc
     7681 tatgtatgta gcaaaagcgg agagaaaaga tcgtataaaa gaggaagtag atgaaatcat
     7741 ttgttggctg acgggttatt cccaaacaga actagaatat caactacaaa aacaagtgac
     7801 tttcgaacaa ttttttgcgg aagcccctgt ccccaatcct tcacgttcct tgattacagg
     7861 tgttgtttgt ggtgtacgag tagaagacat cgaggataac ttgatgaaag aaattcgtta
     7921 tttagataaa atgatcgatg agctagcaaa aggcaaaaaa atggaaaaga tcctcagaag
     7981 ttgatttttc cagagatatt cttctccttc gctcattttg taacatttaa tttggtaaaa
     8041 tgactagttc acgttaaaat aagtcaaagg aggttttctt atatgtttga gacgattaaa
     8101 caaaatattc aaaaatacgc cttattaaga gctgctgttt atattatttc tgggattgcg
     8161 attgtgctaa acccttctgc tgtttttcat tttatcggtt atctgatcac cgcctatctt
     8221 gttttgcttg ggttgttgaa tctttttgag gcttaccgtt ttaaaaggaa aacaggttct
     8281 tggagtatcg gtctgttcag tggtcttttt ttcctgatct tagctctgat cgtctatgct
     8341 tttgcacctg caatcgtttc tatcctgccg attcttcttg gattagctgt tatcatcaac
     8401 agcttgttcc agttgttctt cagcatgaat acaaaagcta aaagttggag tgtttatagt
     8461 agtattctgt tgttgattgg cggattcgtc ttattgttca atccattcaa aagtttgatg
     8521 cttctattcc aaatattcgg ctttattttg attttcatgg gcatccagga gattatcaat
     8581 ttcatcagaa taagaaaaat gactatacgt taatcatttt tagttattaa aatagaccgt
     8641 ataaaaacca acaatccaaa aaaatctttt ggattgttgg tttttttgtg agtatatttt
     8701 cctatttttt caataatgta tgttatgcta agttcgggct atattttata caaaggaatg
     8761 atgagaatgg aatttattgg tattttatgc ctgatattga tttcaacaac gattggctca
     8821 catatctcgc ggagattagg tatcccagca gtgattggac aattacttgt tggtgttttg
     8881 ctaggccaag ctggattgaa ttgggtcaaa cctgatattc tagtccatga cttttcggag
     8941 attggtgtga tcttattaat gtttttagct ggtctggaaa gtgatttatc tcttttgaaa
     9001 aaatatttcc gacctggtat gttcgttgct ttgcttggga tcatcttccc ggttgttttt
     9061 ggctggttga caggcaaagc attccaagtt tcgggaaatg aagcgatttt ctttgggatt
     9121 attcttgcgg caacttctgt cagtatttca gtagaagtat taaaagaact aaacgtagtg
     9181 aatacaaaag aaggatcaac aattttgggt gcttctgtgg tagatgacat tttagtcgtt
     9241 ttagttctaa gtttcagcct atcttttcta acgggggaag cttctagcaa tgcttcttta
     9301 ccgcttgttt tgattgaaca gctaatttat tttgttttta ttttcttatt agtcaaatgg
     9361 attgcgcctt tcctactttc atttgcagaa aaagtgtacg caaattcttc tattatcatc
     9421 gtatcgctag ttatttgttt aggaatgtct tacgtagcgg atcttgttgg gcttagctct
     9481 gtcattggtg ctttttttgc tgggatagct gtcagtcaga caaaggttaa agaagaagta
     9541 taccacaatg tagaggcttt aggatatgca gtatttatac cagtattttt tgtcagtgta
     9601 ggattagaag ttgatttttc tgactttagt gaacaactac tctttatttc tatattgacg
     9661 cttgtagcga ttttgaccaa attgcttgga ggttattttg gtgctcagat tgccggtttt
     9721 tctcaacata gttcattgat ggtcggtgct ggtatgattt cgcgtggaga aatggctttg
     9781 atcattttac aaattggaca gcaaagtcaa ttgatcgaac cacagtacta ttcaccttta
     9841 gttatcgtga ttttattaag tacacttatt tctccacttg ttctcaaata ttttacaaaa
     9901 aaagtttatg aagtgtgagt aaatcaaaaa gaagttgtga aagagacatc gtgaaaaccg
     9961 tttatttgaa aaaaggactg tgacgataac gccacagtcc ttttactgta cttaaaaagc
    10021 aattttttat tgataatttt ggttgaggta ttgcaatagt tccgatgctc gtttggttgc
    10081 tgaatcatca tcttctttat tttccaacat gctgaccatc atataacctt ggttatcaag
    10141 attgaaagca aacaagaaac tgttctcttg cccctttaca tcctgttttt ctttgatttc
    10201 cgctgtacca gttttcgctg ccaacggaat ccctaaagca gaaagagaat gtgctgtacc
    10261 atttacatct tgcacaactt ctctcagatc tggcacgatc gtttgtactg ctgtttcgct
    10321 gatgacattc ttcttatctt ttgtctcttt atctgcaatc aatttaggat agacaagtgt
    10381 gccattgttg gtaaaaacag aatacattgc tgcttgctgg ataggagtaa ttagaagttc
    10441 gccctgtcca tatccagtat cagctagcaa gatatctgag ttaaagctat cttcattaga
    10501 aatttgtgct ggattcatac taattggcaa atcaaggtct tcaccaaaaa tgaatttatc
    10561 taagcctgta cgaaattttt tctcacccat tttcaacgtt tcttgtgccg catatatatt
    10621 atcggaatag atcaaagcag tttttaagtc tacttgtgat acatcactac tgacacgcgt
    10681 tgttttaaaa gatccccaag aactgtcttt ttgccattta agcccgttga tcgtcaacac
    10741 ttcatttgga tcgatagcgc cgttgtcgag accgattgct gctgtaatca ttttaaacgt
    10801 agatccagga gcataacctg tcgcaaatcg gctgatgaat ggatgttcag gattttcttc
    10861 ataagctttg taatcttctt gtgagatccc gtttgtcatt ttgtttggat catagcttgg
    10921 agagctagca agcgcaagaa gatcaccggt ttttggcgtt gtcgcaacag ttgatgcagc
    10981 ttttcctcct agactgtcaa aagctatttt ttgtgccttc gcatcgattg tcaatttgat
    11041 atctttgcca ttttgaactt catgttcgat cagaactttt ttctctacac cgtctgcatc
    11101 tgtaatgctt aatttcccac ctgttgtccc acgaagatcc ttatcaaaag ccatctccaa
    11161 acctgagcga ccgatttttc cattactgct taattctgga ttcttatcaa tatcttctgc
    11221 tgtgatatct cccacgtaac caatcagctg agcagctgct tcacccaaag gataatatct
    11281 gccgtctact tcttgaatgg tagctccagc tggaagttct ggcgttgctc catcaatgat
    11341 tttcaatggg acaaagtaat cgggttgtac ccagctttgt gaaatcgcct gattgatagc
    11401 atcttctgtt aagtcgaagg aggaagcaat cgctttgata ttggctgttt tttcgcctcc
    11461 atctccaagt ttacttggaa cgactcctaa ttgttttagt ttgcctgttg ttgctaatgg
    11521 ttcaccattt cgatctataa tattccctct tgctgcttct tgtgtggtca ggcttacttt
    11581 gtcatttcct tccatttctg gaaaaaccaa gttgggttgc cagttgatcg tggtttgacc
    11641 atcatttctg tctaatgttc ctttataaga aagatctttc aattcaccta atgaggtatt
    11701 catctttgct ttatatgaaa aactgtaagt agaatcgtct tttttatcta cttttagatt
    11761 cgatatctga agtcctttga catcagcagc accgtatata ttctggtatt tatctaagat
    11821 ctctttttca gataatgcac ttttatttgc cgcctttttt gatgtcattt ctgcagcttt
    11881 gttataatct cccttgttca aagcttggac aaattgctca actgtctttt ctccagcttc
    11941 tactgcttgg gtttcttgat agtgctggta gtaaaaataa ccgccacccg cagctgctat
    12001 taagatcact gcgccggcaa tataagcgcc tgttcgattt ttgccgtgct tgtcacttct
    12061 tttcattttt tcctccttct cttgcttgtc attcctttat ttcactattt atacctgttt
    12121 attctaacat atgtctttga ggaaatccat accacaatcc agaagcacac tttctggaag
    12181 gttcgtttgg atactaccaa gtaatttccc aaccgctttg ggtagcttga atattgaagt
    12241 tacgtctttc agctgctgag agatagcttt gatcacttgc tgctgccttc tgatcctccc
    12301 gaagtctcct tctttgtctt cccgaaatcg agcatactgg agtaaagtat taccatccat
    12361 cacttgctct cctttgttta tatatacgcc atctaaatct agagattttt ctgcatcgat
    12421 cttgactcca ccaggaaaca gttcattaac gcaatcgata aaatcttgaa atgtgatact
    12481 tgcataatag ggagcttcaa atttgaaatt ttcctttaat gtttgattta ataaatcaac
    12541 tcccccataa gagtaagctg catttatctt attcattccg taacctggaa tatcgacata
    12601 tgaatctctc atgatagaga tcagttttgc ttgttgtgtt ttctggttgt attgtgcaac
    12661 cagaagtgaa tccgagcgac ctccaccaat cgatcttttt tcaccgcatc tcctcctcac
    12721 acagcaatcc acttgtcagg tgaggagcga gtttgtctca tcaaataagt cagtcacaaa
    12781 aatataaaga aaaggtcaga aaccttttcg aacaagaatt ctgacctagc atcatctcat
    12841 cgtccgagtt ttagcactat acaacgtaaa gaaaacattc ttagctattg gaaaaagcct
    12901 taatccaaca gtttctgttt tacccattgg cgactttcga cgtttctggg caacagccta
    12961 tgtttgtata ggagcctcac ctaacaaggt tattactata ttctatttac gagttcatga
    13021 tagacttttc ctaatgatta ggcaatggaa tttgaaatga aatagtgaaa tttaacaatc
    13081 tttaatattt tttagaaaaa aataacaaat aagttgaaag aatcccgttg caaattcttt
    13141 cagttgcacc aggattcttt gataattttt tagttttatg tgttttttta tatgtttttt
    13201 cacttttcgg aataaatatt tatttgttaa agtaattaaa caatccgcta atcgtttgat
    13261 ctggcatttc tatttcctta ccatctaaag taacagtagt aacgacaaaa tggtcttgca
    13321 atggcggaac ttctaagtac tgcccttgca gaaaatcatt cactgtttca tattcttttt
    13381 tcatttcttt tgaatctgtc gatggtttat agcttatttt taacataact agtgctcctt
    13441 tttattcggg acgtgcaatc gtgaaaattt ctcctattgc tgcataatca tttcctgcca
    13501 aacggcttac agcattcaat tttcttggat cgatccttcc tgtcttatca tcatagactg
    13561 tttcatttaa atgatatttc tgtacttcta gcaaaaataa atcagctgtt actttatttt
    13621 tattccgtat ctcgacatgt tcatataagg atgtttcaaa acgaactttt gcttctgtca
    13681 atgctggtac tgaaatgatt actgaatcag ttaaagtcaa gtcagtcagg tacagttcgc
    13741 tttcctcatt aggcagattg gctgctgttt tatttacttc ttctacgttg tcctcatcaa
    13801 ggatatggat aacagcttct cttgtctcaa gaatattctt tgctgtgtct tttactgcat
    13861 cttgttttct ctggatcgcc aaggataaga tgggtcgatt cgaactgacg atattgaagt
    13921 aactgaaggg tgcgatattc actatatctt ttgctgattt agtcgttact actgctactg
    13981 gtctagggat gactgaacca atcagcaact tgtaattttc acgttctgtc aattctgaag
    14041 gactccgttc aaacatggtt tcgccttctt tctataaaat tcgttaaaaa gcagatcttg
    14101 aagacaaaat gaaaagtaat gcttttttca tcttcttaga atctgcttta aactatctat
    14161 caatttttct tttttgtcaa gaatctgtgc cgtgcgtgtt ttttagttat ttgctttact
    14221 tgcggcttcg acatatcttt tagtgatcaa ttgcggacgg gtgataatag atccaactac
    14281 gactgaaaaa gcacctaatt catatgcttt ctctacttgt tcaggagagt cagtatgtcc
    14341 ttccataatt actgggatat cgacttgttc tatgatttga ttcaataaat caaaatcagg
    14401 tgtctgcgtc tttcgtgaat attctgtata gcctgctaaa gtcgtagaca aaagatcaaa
    14461 accatcttct tgcgcttgaa gcgcttcctc aaaagtcgaa atatctgcca tagctaaccg
    14521 accgtgttcg tgaatcattt ggacaagttc agcagttgtt ttttctgtcg gacgtttacg
    14581 agaagttgca tccagtgcaa tgatttctgc ttgcgtctcc aaaagttctt ccacttcttt
    14641 ttctgtcgca gtaataaaca cttctgaccc atcgtaatct cttttgataa tccctattac
    14701 cggtaaatca acgattcgct tgatttcatt gatatcttct gtcgtatttg ctcgaatacc
    14761 aactgctccg ccttcttttg cagccaaagc cattctcccc ataataaaag aactgtgtag
    14821 cggctcgttt tccaaagctt gacaagaaac gacgactccg cctttgattt gttccagtgt
    14881 atccacaata tctcctccag taatgttata taaaaataca gcttcatata aaaatgtaac
    14941 ccttttctat tcaggagaca ataatgagct atttctttca gcagaccttt cttactaaaa
    15001 gaaaattact tcaaattctt cgtatacgac cagcttctct tctgtaaatt ctatgttcaa
    15061 cgcttcttta taagcatgtt taaaaaactc agcatggact ttccgccaat aagctaatgt
    15121 ccgatcccct tctccttctt tccaagcatg ctctttcgtg acttcactaa aaggcaagat
    15181 ggtcacattt atatttttga tgatacaaac tggttcattt tttccattca ggaccacgtc
    15241 taattgacca acttttggta aaggctcatt ctcttgttta tacagatcgt aaccacttga
    15301 tgtaccagtc tttatctttt ttacaactag ttcgctcaac tcgtctgcca ttttttctgt
    15361 atccccaaat gaaaagaaac ctaatttttc tgattgataa ctaggatatt tttcttggaa
    15421 ctttttgaca tattcttcta cttgctgata cataacatcc acccctttgc tttttataat
    15481 gaaaaaacca tccagatact agtataaaca attatctgga tggtgagcat aatgaattat
    15541 tgaatattca agacacgcag actatcttca acgatttgtt ttggtgttaa atgataacgt
    15601 tcataaagct gccctacagg aacgctatcc gtgaattctt tctctgcacc aaaatttaat
    15661 acgttcattg aagaatcacc ataataacga ctgatatttt cgccaaatcc tcctgacaaa
    15721 ctaccatctt ctaatgtgat gactaattcg tgtgtttctt ttaatttatc taatgtttct
    15781 acgtcatttt ctgtgatcgt tcctggattg atcaacgttg cttcgattcc tttttttcta
    15841 aaagctttta ctgtttcttt tcctaattca agaaaaccgc ctaaagctaa aattgctact
    15901 tttcctccat tatttactgt ttgataggct ggaatactat aatcatttgc gatagctgta
    15961 ccatgttcta caccatgtgt aggaattcgg attgctacag gctgcgctgt ttgttcgaac
    16021 gcccaatcta gcatagagat catatcctct tttgttgctg gagcaagata tttgatgttc
    16081 gggatacttg ataagtaagg aatgtcaaat gttccttggt gtgttcggtc actagctgag
    16141 atcgttccgc caccgactaa aataatcact ggattctcgt tgatcgctaa atcatgtgat
    16201 aattgatcat atgcccgttg caagaaagta cttgattgga agacgactgg acgtactccc
    16261 tgagaagcca aagcagaagc gaaagtgata gagtgctgtt cagcgatccc cacgtcaaaa
    16321 taatgatctg gatgtttttc ttggaatgtt ttcagtccaa aggcgcctgg tatcgctgca
    16381 ttgactgcgg caataggagc tgtacttgtt tgcattttct tatccaaata atccatgatg
    16441 atcatattaa atgtttctcc agaagttact tgctttgcct ccccggtgga cagatcaaat
    16501 ggtacatgcc aatgatattt cattttatta tcgattgccg gctgataacc gcgacctttt
    16561 tccgtatgga cgtgaagtac aatcggatga tcaatatctt ttacttcttc aaataaacgg
    16621 atcaccgttt ccagatcgtt tccattatcc acgtaacgat aatcaaatcc cattgcttta
    16681 aataggttat tgctgctttt accgttggtt tgacgaagct cagctaagtt tttatataaa
    16741 ctgccatgat tctcatcaat agacatctca ttatcgttta ctaatacgat tagattggat
    16801 tgtaaaacac caccattgtt caatccttca aaagctaagc caccacttag ggagccgtca
    16861 ccgataaatg ctaccacatt tcctgattct ttcttcagat ctctcgcttt agctaaacct
    16921 gttgctaagc tgatagatgt agatgtgtgc cccactgtaa aatagtcatg tttactttca
    16981 tgttggttgg aatatccgct cacttcacgg taatgtcctt tttcaaaacc attttttcga
    17041 ccagttaaaa gcttatgacc ataagactga tgggaaacat cccaaacgat tttatccttt
    17101 ggtgaatcaa atacataatg aaacgcaatc gttaattcta ctacacctag attcggacca
    17161 acgtgcccac ctacatcgct gtccttttgc aagatttttt ggcgcatctc ttctgccaac
    17221 tgtttcattt cctcaacaga taattttttg acatctgcgg ggctattgat tgcatccaat
    17281 acatgtaata ctgtactcat aatacattct ctcctccgta ctatcttctt ttaatgaaaa
    17341 tagatttgtt acactttatc tattctacta cttagagttg actctaagtc aatagcattt
    17401 taaaaaaatt tcagagaaag cttgttatat aagtagatct tcgcacgaat caggactcaa
    17461 ataaaaacct tctacagaca attaaaaagc tttgtagaag gtctcctaat taaggtctca
    17521 tcaagaaata tgttttttta ataggtgaag ttcctgagca atatgataca aatggatgtt
    17581 tgcacctttt aatgagattg gatagatctt tgtcttttca gtttctaatc cattttgata
    17641 gctagcagca tcgcacaaaa ccactctttt tttcgcacat agacattcat caggcaattc
    17701 ttctaatgaa cgaaataaaa taggatttat ttcagcgatg ccttcttccg catacaaatg
    17761 aaattgggtt cgataaaaaa attgtttgac tgaactttct gaaacaacaa aaatttctat
    17821 ttcctgtctc cccgcttgtt cactgttgat caaagaaaga cttttgacga attttcgaat
    17881 gaaattttca ttccatctta gttggatttg atttttcttt ttccactctt ccaatatttc
    17941 tacaattttt ccgtacagaa gttgttcttt ttctgataga agatagatcc tttccggtaa
    18001 aaatacttgt ccatctgccc acaacgtacg gacaaattgt aaaaaggatt gcttgaaaat
    18061 aaaattttct gcatcgtcga tttcagcgat actaataatc tgtaaaatca attcattcag
    18121 tgataggtca ttgagaacaa aatttttata aacaacttcg aaatcttttc ttaacagctc
    18181 catgttctca ttggtataat ttctactgtt gaacaaagaa aaaatataat agacatcttc
    18241 ttcttgtaag tctagaattc ctttttgctc ttccaatcct tgacagacta attgaaataa
    18301 cggcttcgtt tctgcgcttt tcttatcttc ttctttcagt ccaaggggaa atgcctttct
    18361 tccgattgcg atctctattc ctcgtatgat aaaggacttt tcatcttccg aatatcttct
    18421 tttaaaaaaa tgagtctcta cataatcaat caactcgtta caagcttctt ctacatacgg
    18481 atttttattt tcatagcctt cccaattgac ataacgtact aaagctagca agatgttccg
    18541 cgagtcaaat tctgggataa tgatttcttt atttttcaaa taatcatttt ctttaaaaaa
    18601 atccaatacg atttttttga ttgtatatac tttgctcaaa gaaataaatt caagatcagc
    18661 cagttctgta ctcgtgaata taccattaaa ataataactt aaaaacttta aaaaataaga
    18721 ttgaccgtac agaaactgtg tgagctcaga aagagcaata ccatgtttga atacgagttt
    18781 atacttatgc ttctctctta cttgttcttt tatacaatat tctagacact cggctagact
    18841 ttctagatcg tgaaggatcg ttggtgtagt cacccttaga gaaatagctg tttgttcgat
    18901 gtctatttct tggaattcaa ataattgttc acacagatac acttttctaa atatatttcg
    18961 ctcgatgtaa ttttccagca ttcctgatac acgcctccag tttttcttat gattttattt
    19021 aatcatatct gtaaatcgta tttttgtttc ctttttattt agaaaagccc tttcaaaaac
    19081 caataaaaaa agaaactggg acaaaagtca aacaagctca caatttcagc ctcattgtag
    19141 gtagctttga gccgtttgga cttttacccc agcctctttc aagaatggtt attcaaagat
    19201 gtcagcgtct agttctttga ctacatcttt caacaattgg ataccagctg cgctgttacc
    19261 aaatggatct agtgccgggc tgaagacacc tatgccgtaa cgatttggca cagctgccat
    19321 caacccgccg cctacaccgc tttttgcagg tacaccaaca tggacggaaa actctcctga
    19381 ttcatcatac aaaccagcag ttgtcataat tgatttgacg attgtagcac tttcttcagt
    19441 aatgatttgt ttgccattcc aaggagcaat tcctttattt gccagcacag cagctaattt
    19501 tgctatgcct gtagcggtga cattgaggga gcattgtctg aaataagcat cgagtatctc
    19561 cggtacgtct ccttcgatca tttgattacc tttcatatag taagcaagag agcgattgat
    19621 atcacctgtt cttgattcag aatgatagat ttcttcattc aatgtgatat taggatcatc
    19681 acagatctct ttcataaatg acaagattcg ctcaaatttt tcatctgcat ctttaccggc
    19741 aatcaacgag gttgttgcaa tcgctcctgc attaacaaaa ggattcattg gatgtttgcg
    19801 atgattgatt tccatattca tgatagaatt gaaggcaaaa ccggttggtt ccgtgttgat
    19861 tgtttgaaag actttttcta ttccgttgtc tttgattgct aataacaata cgggaacttt
    19921 tgacatgctt tcgatggcaa agcgcacatc ggcgtctcct ccctcaatca gttgttttgt
    19981 atccaaatca taaatcgcca tacctaattg tttgggatcc acttcagcta atgctggaat
    20041 gtaatccgcc acttgtcctg tttgataata gtggaaattt tttccaatca attgttctaa
    20101 ttcttttact tccatttgaa taaccagctt tcatttttta tttttctgca tgctggaatt
    20161 tatgacggca tgcgtagatc gtaaatggaa taactaagac gataagataa gaaacaatca
    20221 gaatcgtttc ataaatccca tgctgtccag ctgcgatact agcaggtgga acaaatgaga
    20281 tacaaaaagc aaaaagtgaa gtcaaaagac ctaaacaagc aacgattact tttacaactt
    20341 ttccgcctgg aacctgatag gctctttcaa gactgtcatc tttaaaaacc agcttcaaat
    20401 agcccgcgaa aaacataaag tacaacatca ggtagattac aacagtcaat gacatcgctg
    20461 caagaaatga aagattattc cccccgccgc ttaatgtaaa gacggctgcc cagattgttg
    20521 caacgatccc atttgcgatc atcaaatgag caggaacacc gtgtgtgttt tcttttgcaa
    20581 aatattcagg aagtaatcct tcttctgctg ctacgtgaag tgcttttgaa ggagaggtta
    20641 cccaagaagc aatttctccg atgacaccta aacaaacaag aatcgcaaga attttcgcaa
    20701 tccatgcaag atttggatca atgtgtctta ataggaattc taacgattga atcacccctg
    20761 tattaagaga caaaccatgt tgaggtactg tagtagcgac ggtcaatccg ccaaaagtat
    20821 ctaaaatgat tgccagaata accaatacaa acattgctaa tggataatcc tttttagggt
    20881 tttccatttc atttgcatga ctggcagatg tttctacgcc catatatgct aaaataaagg
    20941 aaacaaaaac aaccagcgta ggcaatttcg aaaaatcagg aatcaatgtt ttcatagaca
    21001 gtatcgtttg tagtggagcg cctgaagcga cataatggat ccctaagcca aacaagacta
    21061 atgctggcaa caagatacca gctacaaaac cgatccgagc aatcaatgaa gtgtatttgg
    21121 ttccttttaa ctgtgagagt aaaatagccc agaaaataat caataggatt gccaatttca
    21181 gatatttatt gttttgtata gcaccaatac ccgttgcata ggataatgca ccagttaaga
    21241 aatacagcat ggtcaagtag ccaactgtta tctcaaacca ttggaaaaag attgcggcaa
    21301 aaccgaatcg ttttcccaat gtgcgactga cccaagtata gacaccgcct ttttcccatc
    21361 ctttcaccgt tgccatctct gctgcgcaca atgccacagg gataaaccat agcaaaccgc
    21421 ctaataacaa gaaaaatact aagctgaagc ctgaggtcgc gaatgtggga tattcatata
    21481 atgaaacgac cattgagatg gtcatagcca aaaagccaaa gaacgttaat ttttttgcag
    21541 gaattttcgt tttgctttgt tgcatgaatc ttcctctttt ctatttgaat ttgtttcaat
    21601 tgagtttgtt gccaaagaag aaaaagtcca atccttcttc ttgttcttct tttgtagtag
    21661 tgatcgttgt aaagtgcatc gccgatttta aaatcactgt tgtcagcaca taggcataca
    21721 cggcagtaat gatgacacca atcacttgaa tccctaagaa gtaccagctg cttggattcg
    21781 ttagtaaatg gctgttagat gcaaagatcc ctatcagaat cgtacctgtg aatccgccca
    21841 tgccatgaac accccacaca tcaagtgcat catcccattg tttcttttta cgaaaatcaa
    21901 cagcagcatg acagacgata cccgcaatga tcccaatcag catggcactt tttgcttcta
    21961 cataaccggc acaaggcgta atggctgcca atccagcaac ggatcctgtt agtacgtcga
    22021 caaaatcaaa gccatttcct tttacttttg caatgatcag ccaagtaatc atcgcaaatg
    22081 caagagcgat gaatgttgaa ccaaatgcat tgactgcttg ttcatctgct cgaagtgcac
    22141 caccggaatt aaaaccgaac cagccaaacc aaagcagtcc tgtaccgata gcagctgcca
    22201 taagactgct atgctgactt ctttctccta aaggaatctt tctttgacca agtgtgagga
    22261 tacatgctaa agagccgaat ccagctgtcg tgtggatgac tgctccacca gcgaaatctc
    22321 taaatcccat ctgatccaaa aatccgccac cccatatcca gtggcaaaca gggaaataaa
    22381 tcagcagatt ccaaaaaata acaagtataa tatagccttt taaattcaat ctccctgcaa
    22441 aagctcctgt catcaaagga acggtaatca cgataaacat cagttggtaa agaaagaaca
    22501 ttaaaaatgg aatcgttgca ccatgaaaca tgttggggaa gcttgtaaca tgtctcatca
    22561 aaaagaaatc tgccgggttt ccaataacac cgccgatatc ccgtccaaag gccaatccga
    22621 atccaccaaa tacccacata atcgttgtta tcccaacgga gagaaaagat tgagacatga
    22681 tcgttagtat attattcttc cgtgctaatc cgccgtaaaa aaaagctaga ccaggagtca
    22741 tcaggcaaac cattgctgta cataaaatca tgaatgctgt atctcctgta ttgataggta
    22801 atgtattcat ttttttcgcc tcctttctac gattacgagt ataaaagaag gtgtagttgt
    22861 ttttttcttc tgtttttttg aattaatact tgcatttata aaagacagac aattaataaa
    22921 agcttgatgt gttgtgctct ttttcgtttt tcacacaaat aaagacaaaa aataaacggt
    22981 cttcttttta tagaaaaccg tttattttcg tcttttttta tttttaaaga tattttttca
    23041 taaggaataa agaatacttc atataaaata tataaaaaag aaccgcagcg agtgtcgcta
    23101 cggttctcaa atttgttctt catttcaaca taagtttttc ttcaatttgc ttataattta
    23161 cgtgcaaaga atgaaacgac taatactaaa atgattgcac cgatcaatga tggaatgata
    23221 gccattcctg caattgttgg tccccaagtt cctagtaaag cttgtccaat tgctgaacct
    23281 actaaaccag caatgatgtt tgcgatgatc cccattgatg atcctttatt cgtgattgct
    23341 cctgcaattg ctccaatgat accgccgacg attaatgccc aaataaatcc cattttaaat
    23401 tcctcctaac tgacttctta cttcttattg tacacgtggt tcgttatttt ctttgacttt
    23461 ttgtgcacct ttgcctacag cagattttgc tttatctgtt tggcgtgaag caaattgtcc
    23521 tgtggatttt gctgcttctg ttactttgtc ttgtactgtt tcttgatctt tttggtattc
    23581 ttcttgtgtt ttgatgtctg caacattcac attcacttcg ataacatcta aatgtgtcat
    23641 attgtttact tcagtactga tcaattcttt gatttggttg taaatatctt cgatgtcttt
    23701 accgtattct acgatcacat ctagatccac agctacttgt ttcttaccta cttctgtatt
    23761 gatacctgct gttacgttat ctgtgttgac taatttttca gccatatttg agaaaaatcc
    23821 gccatctaat gtcaatagac catctacatc tttcaatgca taaccgatga ttttttggat
    23881 gactttgtct tcataagtca attcaccatt catcatgcgg ttttctcctt tttcatttgc
    23941 caaaactgat ccatttgttg tattcatgtt tttgttttcc atctttgttt cctcctatga
    24001 tttaaaaaat tgatcaacta ttcctgactg tttcaaataa aaaccgattc ctgcgccaat
    24061 tgctgtcatg attatgatca acaatgtctt gaaaaatcca atcgttaacc ataaaacagc
    24121 tagcagtagt ccaagacccc caaagataat agggagcttg tatgctgaaa atagttcttt
    24181 cattatttgg ccctcctatt ccactcgaga gtgcttgtag tctcttgtat cttcttgttc
    24241 ttcataaccg ctgtatgtga ctgccacttt gaccgtttct tttgttccga gtactttagt
    24301 tacttcttct tcgatatctt gcatcaatac acctgttttc cctactaatg aagaagttcg
    24361 tttcaagtct ccgttgacat ggatatggat tcgatttttc gttgaacgta tccgtacttt
    24421 aggtgaatga atgaactctt cttcgtgtaa atgggaacgt accaaccctt cgatcgcttt
    24481 tttgtcgatt gttagtttgc catcttcccg tttcataacg aaagttcctc ttgactttgg
    24541 atagaaaaga acgactagca agatgataat agcaagaacg gcaaatacta cagctgccca
    24601 gaaaatatat tgttgcatgt agtaattcgt taaagtaaag aagcgaaatc gttccaattg
    24661 ttcaggcata atatacggcg cattgatcaa cgcaatcgct agaaatactg aaagtagcag
    24721 taaactcatg ataacaccga ttatttttaa ccccttattc attttccacc tcctataaac
    24781 ttatttttac cctgtaaata actctaccga caatcacagt atagatagcg aacagttagc
    24841 atagcatcag taaataaagc gctaccaaac attgctggat cataacggcg ttttattgcc
    24901 agtctgatac tgaaataaca attgcttact tattctctat ttacttttga ttgctggcta
    24961 tacttaaagg atattattca agattaaaaa ttgcaaagat tatgctcagt tattattaca
    25021 agattctatt tattt
//
LOCUS       DAIGSZ010000042        24341 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.042, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000042 DAIGSZ010000000
VERSION     DAIGSZ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.042"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(111..656)
                     /locus_tag="NOB31_001785"
     CDS             complement(111..656)
                     /locus_tag="NOB31_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCI0973991.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(668..1360)
                     /locus_tag="NOB31_001786"
     CDS             complement(668..1360)
                     /locus_tag="NOB31_001786"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HCI0973992.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1379..1663)
                     /locus_tag="NOB31_001787"
     CDS             complement(1379..1663)
                     /locus_tag="NOB31_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0973993.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1676..2239)
                     /locus_tag="NOB31_001788"
     CDS             complement(1676..2239)
                     /locus_tag="NOB31_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI0973994.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2467..3129
                     /locus_tag="NOB31_001789"
     CDS             2467..3129
                     /locus_tag="NOB31_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HCI0973995.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3253..4449
                     /locus_tag="NOB31_001790"
     CDS             3253..4449
                     /locus_tag="NOB31_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HCI0973996.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4550..5926)
                     /locus_tag="NOB31_001791"
     CDS             complement(4550..5926)
                     /locus_tag="NOB31_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0973997.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5963..6829)
                     /locus_tag="NOB31_001792"
     CDS             complement(5963..6829)
                     /locus_tag="NOB31_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HCI0973998.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6918..7943)
                     /locus_tag="NOB31_001793"
     CDS             complement(6918..7943)
                     /locus_tag="NOB31_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0973999.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7961..8635)
                     /locus_tag="NOB31_001794"
     CDS             complement(7961..8635)
                     /locus_tag="NOB31_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0974000.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8819..9712)
                     /locus_tag="NOB31_001795"
     CDS             complement(8819..9712)
                     /locus_tag="NOB31_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0974001.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9786..11483)
                     /locus_tag="NOB31_001796"
     CDS             complement(9786..11483)
                     /locus_tag="NOB31_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI0974002.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11476..12789)
                     /locus_tag="NOB31_001797"
     CDS             complement(11476..12789)
                     /locus_tag="NOB31_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCI0974003.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12789..16826)
                     /locus_tag="NOB31_001798"
     CDS             complement(12789..16826)
                     /locus_tag="NOB31_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCI0974004.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16839..17297)
                     /locus_tag="NOB31_001799"
     CDS             complement(16839..17297)
                     /locus_tag="NOB31_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0974005.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(17595..18113)
                     /locus_tag="NOB31_001800"
     CDS             complement(17595..18113)
                     /locus_tag="NOB31_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCI0974006.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(18115..18732)
                     /locus_tag="NOB31_001801"
     CDS             complement(18115..18732)
                     /locus_tag="NOB31_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HCI0974007.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(18729..19583)
                     /locus_tag="NOB31_001802"
     CDS             complement(18729..19583)
                     /locus_tag="NOB31_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0974008.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(19580..20491)
                     /locus_tag="NOB31_001803"
     CDS             complement(19580..20491)
                     /locus_tag="NOB31_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCI0974009.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAVSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(20532..21866)
                     /locus_tag="NOB31_001804"
     CDS             complement(20532..21866)
                     /locus_tag="NOB31_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0974010.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            22074..22904
                     /locus_tag="NOB31_001805"
     CDS             22074..22904
                     /locus_tag="NOB31_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HCI0974011.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(23148..23430)
                     /locus_tag="NOB31_001806"
                     /pseudo
     CDS             complement(23148..23430)
                     /locus_tag="NOB31_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011066964.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(23588..23782)
                     /locus_tag="NOB31_001807"
     CDS             complement(23588..23782)
                     /locus_tag="NOB31_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974012.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
BASE COUNT         7163 a         5289 c         4209 g         7680 t
ORIGIN      
        1 ataagttttt ttaaaataac gtataaaaaa gagcataaaa caaagtcgtt tgttttatgc
       61 tcttctttta ttattttgtg ctttttattt tatcaaatca ctttgttttt ttataaaatt
      121 tctgcgccta gtgtggactc aaaatgtctc aatgcccatt catgtccaac gggatcgaaa
      181 cttgccacgg aatctttgaa aatatggagt ttgtatccta gattatacgc atcgactgct
      241 gtatgcaaca cacagatatc tgtacatacg ccggtcaaat aaatatctgt gatctggcgt
      301 tctcgcaaac ggatgtctag atctgttcca ctaaaagcgg aataatgccg tttgtctatc
      361 caataaacat tttcctcttg ctcatagtct tggtataaac tttttaaaga gccgtacaat
      421 tcccgtccac ccgttcctat cacattatgc ggaggaaata agcggttctc cggatgaaag
      481 gaatcttttg gatcatgcgc atcaatggca aaaacgacaa aatccttttg atcaataaac
      541 ttctttgtat gagcagtcag ctttttttca attacttgtc ctgctgtccc agtagtcagc
      601 tttccatcct ctgcaacaaa atcatatgtg tagtcaatcg agatcaatgc gttcatctta
      661 gtcctcctta tacgagatgt ttgacaaatt cgatcaccat ttctgctgat cgtttgcctg
      721 cgtcttcgat aaattcgtca aagctttgtg tcgccgagtg atctgctgtg tcgctcattg
      781 cacgtacgat caaaaatggg atattgaact gacgagctgt ttgtccaaca gcggctcctt
      841 ccatttcgca agctaatgct tcagggaaat tcgttaagat ttctttgatt ttatctggcg
      901 agtcgacaaa tgtatcacct gtaacgatca atccttcttt tgcgttcaaa ttcgttgctt
      961 ttgctgcttt aaccatttca ctgcgcaaat atgtgcttgc ttcataatat agaggcattc
     1021 ctggtaattg tcctgggttg tagccaaatc ctgttgcatc tgcatcaaaa taagctactt
     1081 tgtctgatat aacgatgtca cctacttgta agccttcacc gattccgcca gctgaacctg
     1141 tattgatcac catgttcacg ccgtattgtt ggatcaacag acttgtggta atagatgcta
     1201 agacttttcc tataccggaa cgtacgacga tcacttcgtg gttacctaat gaacctgaaa
     1261 taaataaagc gcctgcgcgt tcccatgata atggttcgct taggttctct ctcaaaattt
     1321 ttacttcttc ttccattgcg ccgataatac cgattttcat ctttttaatt ccttctttct
     1381 atataaatgc gattgctaaa aaaaccacac ataacattag gataacaata ataagagatt
     1441 tcatcaaaaa agagttccat ttggtcgtct tttcccgttc gctgatcctt gttttcgtga
     1501 ttggtttatt ctttttgctt tctttacgat aaaagctggc aatctttttt tcttcttgct
     1561 gataagctgt ttctgctttt cgctgttttt ttaatgactc gcttgcttgt gcttgttgtc
     1621 gcttgcgaag ttcgcttcgc gtaataagcg gtcctttggc cataagccga tccctctact
     1681 ttcctttggt caatagttcc cagtattgaa tcgcataaat cgtctttgca tcacaaatca
     1741 actgatcttt catcgcttgt tgcgcctctt caagagttag atgatacaac tccagtactt
     1801 cgtcttcatc ttgtgctaaa ggattctcga ccttctctac cccttgtgca tgataaatat
     1861 gaaggacttc atttgcaaaa cctggtgaaa gatacatcga agtaagatgg ctcagcgact
     1921 tcgcacgata gccagtttct tcttctaatt ctctagctgc tgtcatttcg ggattttgtc
     1981 cttctcctgg atcgattttt ccagctggaa tctccaaaat cactttttct aaaggttttc
     2041 gaaattgttt gacaagaagc agacgatctt gttcgtcaaa agcaatgatc ccgacaccgc
     2101 caggatgaaa taccagttct ctcttcgaag ttcctccatc tggcaaacga acttcgtcta
     2161 cagcaacatc aataattttt ccgctataga tttctttgcg actgattgtt ttttcttcaa
     2221 attgctcatt gttcagcata tcttctcctg ctttctttgt aatcataact gctttttttt
     2281 catttttcaa tttttctcaa aaactcctta ttagtttacc atagataaac cttagatttt
     2341 ctctaaatat agaaaatcct tctttagtcc gatactcttt ctagtagtcc gtatgctaaa
     2401 ataagtatgt aatcgaataa cgaaaagaat tcaatactca acgataaatg acatggaggg
     2461 tttattatga taaaacgaaa ttggccgtgg cttctagcat tggtcttgct atttctcttt
     2521 gtccgaaaca atagtttttc ttttgttcta ggacttttat tgataggtgt agttttagtt
     2581 ttgtggggac tctttggttc gcgcaggaaa aagggaaaac aagaagaaat tcctgcactg
     2641 actgacgaac ttgaaactca ctatgaaaaa agcggtatga cagcgaatga aatttcattt
     2701 tttcgacaaa caatgaatca aacaaaaaat gagatcaatc aattgcaaat gaatatgcag
     2761 cagacagcca aacttaaagc aatcgatctc cgccatgatc cagtcaaagc agcgaaagct
     2821 ttattcaaag aattggtgaa agaaccaaac cgactgcatg aagcaagtca gtttctttat
     2881 acgcatctgc cgaatctagt tgatttgaca aataagtata atgagatcaa tgaccatgag
     2941 atcaaaaaca aacagaccta tgaaaaacta gaagaaagcg cgcagatcat cgaccagctg
     3001 tcagctttaa tcgcacaaga ttatcaaaaa ttcgttgctg aggatctaga tgatatcgac
     3061 gtagagatat ctgttgcgaa acagagctta aagcgtgata ataaatatga accagaacaa
     3121 aaggattaac tcttttgttc ataaaagaag actcggaaca ttcagatgat gtctggctgt
     3181 ttcgagtact ttttctaaag tagagacatt catgtaagaa tcgagaacag attcaacaag
     3241 gaggaatttt ttatggatca taaaccgact gaaacaaaag atgttacacc agttaacgat
     3301 acacttgaag atttattgaa caacccgttt tcaactccaa cagatacgct gaccacttca
     3361 caacaagcgg agattgatca gctccaagag caacagacag ctgctcgttt aattgacaaa
     3421 ctaccggcgg aacgccaaga acaagctaaa cagctagcag caaaaatcga tgctaatgat
     3481 gcacagtctg tcatcagcta cggatcggct gcccaagcaa aattaagtga attctcacaa
     3541 tcgatgttga atcatgtgca agcacaagat attggtcctg taggagattc cttaactgaa
     3601 ctgatgtatc gtctccaaga agccaatcct gacgaactgc gtgccggaga agggaacatc
     3661 ttccagcgtg tcttcgggaa ggtcaaacaa tcgatctatg aagtgacagc aaaatatcaa
     3721 aagattggtg cacaaattga caagatttca gtgaaattag ataaagaaaa agacggtctg
     3781 ctaaaagata atctgatgtt agaacagctt taccagaaaa acaaagacta ctttgatgca
     3841 ctgaatattt atatcgctgc tggagaattg aaaatggaag aacttcaaac aacgatcatt
     3901 ccagaagcga tgaaaagagc agaagaaact ggcgatcaga tggatgttca gattgccaat
     3961 gattacacgc aattcctaga tcgtctggat aaacgtacgc atgatcttcg cttagctaga
     4021 cagatcacga tccagcaagc accacaaatc cgtttgatcc aaaacacaaa tcaggccttg
     4081 gctgaaaaga tccaagcatc tatcgctaca gccattccgc tgtggaaaaa ccaagtcgtg
     4141 atcgcattga ccttgcttcg tcaaaaagat gcagtaactg ctcaacgcca agtctctgaa
     4201 acaacaaacg acttattgaa gaaaaattca gaaatgctga aaatctcagc catcgaaaca
     4261 gcgaaagaaa atgaacgtgg aatcgtggat atcgagaccc ttcaaaccac tcaaaatgat
     4321 ttgatcgaaa caatccaaga gacattgcgt atccaaaaag aaggaaaaga aaaacgtcgt
     4381 catgcagaag tagagcttgg acacatggaa gaagatctga aacaaaaact gttggattta
     4441 acccaataga tcacctttcg cttgttacta aaacaaacgc ccaacaacag tttattacaa
     4501 ctgttgatgg gcgtttttct tatctttctt ctaacttctc cattggagtc tatttctcat
     4561 tcatcttgct gtgtccatag ccatagccaa aataaatgat cagtccaata accattacga
     4621 taccgaacac gatccatgtc acagtttgca gacgaagcat caatacaata caagtcaaaa
     4681 tggagacgat tggcaatagc ggaacgaatg gcactttgaa ttctccagct tttggtttgc
     4741 caaacatttt tctcaacttc agtaagccta gactaacaag catcaaatag gcgagcgcca
     4801 tgatattcgt tagttccgct aatacattca atgggaaaaa tccggcaaag aatacagctg
     4861 ccacaccagc ggcataagtc gcttttttcg gtgtacgatg cttttgatcg atttctgtca
     4921 taaacttagg aagtaagcca tccttgctga cagcaaacag taaacgagca agtgaataca
     4981 tcatcgagat cgttaccgtc agtagcgtta aaattgcccc tacagcgatc accgcgccca
     5041 ctgttccatg tcctacatac ctcattgcaa aagccactgg gtcattgact cctagttcag
     5101 tatacggaac gattcctgtc aagatcagcg tcacgatgat gtaaaggaca gtagcaatca
     5161 gtatcgaacc aatgattcct cttggcacat ctttttgcgg gtttttgact tcctcggctg
     5221 ccattgcaac ggcatcaaat cccaagaaag caaaaaacac aagagctgca ccatctagca
     5281 caccggaaaa accaaaaggc atgaatggct gccagttatc aggtttaacg aaaaatattc
     5341 ctacaatgat aaacaacgcg atgataccaa atttgacata taccatggca ttattcaaac
     5401 gtaatgcttt cttggcttca agcgacacga tgtaagtgac gaatatcact acgagcaccg
     5461 caatcaagtc aatgtatgta ccattttccg gattgtaccc gccagttaat gcttgtggaa
     5521 gttcggcccc taaacttttc aaaaaacctt gcatatagcc agaccatccg gaagcaacag
     5581 aggaaaccgc tagtaaaaat tccccgatca acaaccaccc tgtcagccag gcagcaaatt
     5641 caccaaatac aacatacaga taggcatatg gcccaccaat cactggcact cgcgaagcaa
     5701 attctgcgaa acttagtcca gacaaaatga caacgattgc agctaagaca aatgaaagtg
     5761 acagtgctgg accagcattt tgattggccg caacccctgt caccacaaat attcccgtac
     5821 cgatgatcgc accaattcca agcatgatca aatcagacgt ttttagttct tttttcatct
     5881 cactcgtatg attgagattg atctctttct tacgaaacaa atccattgaa gttcctcccc
     5941 attttaggtt ggaaaacagc gattaaactg ttttcatata ccctaaaagg ataccaccta
     6001 aaatgactaa aaggcaacca acaataacat aaatgagctc ttttttcgtt tttctttcgc
     6061 caaggatgaa aatcccacct aaagtagaga taatgatccc catttgtgaa agtgagaagc
     6121 caacagctaa accaagtgat ttgactgtta gaagcatgca gatgtttcct aagccccata
     6181 ataatccaca gatcatgttt ttccacacaa actgatcgac tttaacttta cggaaagcaa
     6241 agaagcttgc gcctaagatc attccgatac tttgaggtaa gataattgac atcgcatcca
     6301 aattcgccca gttgacgatg atggtatata caccataacc aatcgtagag aagatcaatg
     6361 ctctaaaacc cttaccaaaa tcaagcattt tattatctgt atctattttt ccttcgtcat
     6421 cttgtcgggc agtcaaatac gcaccgctta caagaagagc taaagcaata ataccgtata
     6481 cataatcttt cgtttgtgtc cattcatgga agaaaacggc tcccgcaatc gtattcaaaa
     6541 ttaattgaaa accagtagac aatggtagcc ctacagaaac acccatgtac ttcattccat
     6601 ggaactgtcc attttgtcca acactccaag ctaagccgga taaaaatccg atcaagaaaa
     6661 tccaaggggt gattacagga ctaacaacga aaaagacaac taaagaaaac agaaatgcac
     6721 cgatcgtcat tcctagtgtt tgttgattgg catcgccacc aattttacca cttactaaac
     6781 caatactacc ccatgccaac atagggacta atgctattaa aatttccata accaatctcc
     6841 ttttatttca catgataaga aacttatcag cgaaaacgtt aacaacacaa gcactttttt
     6901 tcgtttctaa cgattttcta acgtttttca ttataaaaat ttaagattgg gaaaaataaa
     6961 gtcattgttg tcccttttcc ttcagttgat tcagccgtca aatggatacc taatttttcg
     7021 gccagatttt ttgctaaata aagtcctaat cctgttgaat gtgttttgct aagtcgacca
     7081 tttctcccag taaatccctt atcaaagatc cgtttcaagt cttccgctgg gataccgatc
     7141 cctgaatctt taactgaaag gctgactcct tgcgcttcct tttctatgct cacaatgatg
     7201 tttccgtgat ccggcgtata tttgatggca ttactaagca attggttgaa gataaaagcg
     7261 atccatttag catcggtcaa aacagtatga tcctcaccaa cgatctcgta gcgaatattt
     7321 ttttggataa aataatttgc ctgactgcgt atcacaggct gaatgattcc ttttagtcca
     7381 tattcttgga tgaggtagtc ccgcgagaaa ctgtcgagtc ttgcataata caaaacttgt
     7441 tctacgtatt catcgatttt tgataattca ttttctagta atgtatactt ttgatcgtca
     7501 atatcgaact cgatcgaacg aactagcaat ttagaagcgg aaagtggcac tttgatttca
     7561 tggacccatg agtcaatata atctttttgg tcttgttgat tactgattgc tgattgcatt
     7621 acttcttggt gttcacggat cagctgattg atatattctt ctaccagttt ttcttcttct
     7681 gtcctcccac cactcaaata attttgcaaa ggggaagttt tttgtatgtc ggctaatttt
     7741 ccccaccatc ttctcttgct caagtaacca cccagcagat aaaaaatcag aaagacgccc
     7801 tcaatcaaag ctaaataagc aattgtgctc aaatcaactt tgatgtttgg cgccagccac
     7861 atcacaaaga tcgtcaatgc aataaaaaac agccatccca agatcaatgt ccactgatct
     7921 ttcaaatatt taaaaaaatt catcttaacc gctcatcctt tcagggaacg atatatccct
     7981 gtcctacttt tgtttcgata tatccttgga tacctgcctg ttcgattttt cggcgtaacc
     8041 gattgatgtt gactgtcaat gtattgtcat ctacaaatcg ttcgtcatcc cacagtgctc
     8101 gcagcaattt ttcccgactt aagatctttc cattgtgctt catcaaaata aataatagac
     8161 gatattcatt tttgctcaaa tcaatgatct ctccgttgat ttccatactt ccgttgtcaa
     8221 cattcaacgt aatgccattg tggctcatca tttcactaga taattctgtg tagttgtaag
     8281 aacggcgaag taatgcattg atttttgcaa tcagtacatc gatttggaaa tgttttgtca
     8341 caaaatcatc tgcccccatg ttcatagcca tgatcatatc catattcgta ttcctgctgg
     8401 agataaaaat gatcggtact ttcgatactt cacgtatttt ttgacaccaa taatagccat
     8461 ccaaaacggg aagattaata tctagtaata caagctgtgg ttcttctctt tcaaagtctg
     8521 agaacacttg attgaaatcg gtcgttccaa aggtttcaaa ttgccatttc tcaagttcct
     8581 ccatgatcaa ttgtcgaatg atctcttcgt cttcgactac catgattttt gccataaaaa
     8641 atccctccat ctttcttctt gctactacaa tatcaaagaa gcccttgtga aacaagttgg
     8701 cttacctgga aaatgtcatt ttagcaaacg ttaaaaaaaa ctggaaatat gcgatttaat
     8761 cgcgtttgtc tcttccaagc agcttaaatt tattatgtta ttcttaataa ttggtctatt
     8821 atctgttatt tttctttcgt tgtttttgtc ttttaaattt tcgataacac caataaccga
     8881 aaagcgttag cactagcaat atacctagaa ggagtataag taatcgataa agatggtatt
     8941 tttttgtctg ttctatcttt gaagagactt cttctgtaaa gggaactcgt cttcctgtca
     9001 ctagtaatcg gtgagtgttc acggtgtaag gtgtacaagt gataagtgtg actagatcct
     9061 gcttttctct aattgctaat gtatttgttt ttgttggaag gacaacaatt ttctcaacga
     9121 cttcataagc gagcatccga ccatacactt caagatagaa tcggtcatct tgctccattt
     9181 cttcaagatc cgtaaagagt tttttctcag caataccgct atgggcggta atcacggaat
     9241 gtgtactctc tcctccagtt ggaaaagagg tgccttgcag gactgtcgct cctctatcta
     9301 acaaaagatc attcgtttca tcaaataaag gcaagctaac attgattttc ggaatataga
     9361 tggctccgat catatgttgt tcgtaatatt cttttcctgg attttggaca tttctaaccg
     9421 cttgctcaaa aggatctttg acttgtccca ttcctgggat tactgatgta tgagcaagcg
     9481 tctgattttt cttttcatgc actgctaatt gttgctcatg tttttcttct ttatcgcgtt
     9541 caagctgctt ttgataattc tcgatccttc tttgatccaa ataattgctg agagcatctg
     9601 ctaaaaatgg atatgtaaaa actgcagctc cggcaagaaa catcactgcc ataaataatt
     9661 gtaataaaag actgatttgg gtttgaggtc tattacctat tttctttttc attttcttca
     9721 ccttcttatt taaaaaaact gcagcaacct ttataaaacc gattgctgca gcttattttt
     9781 gttgcttata cttcagactt cattttagat ttacggtacc agctgtacgc tccaatcatc
     9841 aaacttattc cgattagtaa gaatgccaag agcccgttcc caccagtagc aggaagtgac
     9901 ccgcgtttca tattcggtac tctttctggc cctggatttt ctactcctac gatctgaatt
     9961 tcttcattat agcttccata agagatgata aattcagtaa aggctgcctc acctgttgga
    10021 agtacataac cttctggcgc catggtctct ttcatttgat aggttccata atctaaccct
    10081 tgaacctcaa agtatccatt tccatctgcg acaaattctg ttgcttgtcc gcttgttgcc
    10141 cactcaattc tatctgctcc tgattcataa acagctaaag gcgactcccc tttataaaat
    10201 attgcgtatt cagaacggtc ttcattccac aattcgaatc ttgcatcttt aagcaattca
    10261 ctgcttgatg catcatattt ttcaaacttt cttccacctg ttgtgacttt ctctggcggc
    10321 tctactcctt cttcataatc aaattcatca tttcgtccga tttcaataac cgctgtgttg
    10381 ttatggaaat catccgcttc tagttctgtg gaaaccttca aattatacgt gatcgttaaa
    10441 tctcctccac gtgcatctgc taatctacct aaagtatcta ctttggctac tccattttct
    10501 tctgtcaaaa tcgtcacgac aaacccgttg cttactactt ctactatata atcttgtcct
    10561 tttgttaaaa tcgtctcgcc ggctcgcact tctatttcct gatcataata agttagacca
    10621 actgtaggcg tatctgtgat tttgtaattt ttgataacag cgcttccgtt ttcaaggaca
    10681 gaatcgatga aataaggaat aggtgctgtg atcgtgtaag aagccgtttt tcctctttct
    10741 agatcaatat aagaaatcgt ttcttgttct ccagcttcat taataatcgt tacttgtcta
    10801 aggtcgcttt cctctacatt catctgttta tctgcttctc tgatttcgtt tttcggatac
    10861 aaatgcacat ctgtattgta tgtgtctttc catgtagaac catcccacac gccatccacc
    10921 atatcaggca tcatcactgg catcataaca accattggag acgcgattct ggaaatatga
    10981 gctggcgaat aagtttctaa gaaaagatag actttatctc tagaagaagg tgcttcttcc
    11041 gtcacttgga cggtagagaa taccgcttct ccagcttcat tcgttgtttg tttgtcaata
    11101 cttgtcagtc gatattttaa aaaccaactt tctgtgtgcc gtttttgaat ccattcaatc
    11161 gcttcggcag aattaagacc gtcttctcgt tccggtgtta aaggattatc tcgaatcaaa
    11221 tcgtaatata cttccgttac gtcaaacaaa tcaaaatcga ctcctggaat attttcttca
    11281 ccaaaatccg tagaaaccaa tccgctattc ggtcgttctt ccggaacaga tgagaaacct
    11341 tttttgtgta atgtaatcgt cacttcactt ggtttttgtg cgacttcttc ggctttgact
    11401 agttttccgt tcccgaaaat ccctattccc gcagtaacga gtaacagtac actcattccc
    11461 gtgacaatca tttttttatt catttttttc tccccgttct ttttttatta ataaaacagc
    11521 acctaacaat aaaagaattc ctagtaaaga aatcaacgtt cttgcttcat tcgtttgcgg
    11581 gaatacggac cattttcctg attgacctgg attgcttgga ccactcggct ctttcggttt
    11641 gtccgttgtt tcttttacgg tctcgttata aacacgtggt gttgcggatt cataggcaga
    11701 gactggaact ttcccggatt ctaattcagc catctcctgt ccgttaacta ctacatattg
    11761 tggttggcct tttgcatcca cccaaaattc agggatgatg acctcgattc tcttacttgc
    11821 ttcatccatc tcgtaacctt ccacaccttt taattcttca aaataatagg tgccagaagg
    11881 caagaaacgt tgtcctgtcg taacaaggcc ctctttatcc gaaatgaatt tgcttacatt
    11941 tttgtcattc aaaggatcat tgtctgctgg tttgatccat tgatttttca agtcattagc
    12001 aggagccata tctaaataat atttcccccc ttctatcatc tgatatagag caaaaacagc
    12061 accttctaat ggttttcctt tttcagttgt tcctctttga cgtccatact tgaagaagta
    12121 tggatctctt agataaccga catttttagg atagatatga atctcttgca gttcctcggt
    12181 tgattctgtc gggtgataaa ttggcaaaat agcagcaatt gggatagctg tctgatcgat
    12241 atcaacatcc aatccaactt ctggatcaat cgattcttcg aaaatcaaat aaactgcatc
    12301 ccgatcttgg tttttcttag gtgctttgat acgtgcaatc ccgtctccta atccgccaac
    12361 cgtatctttc ccagttgtta ccgaagtccc tatttggaca agcctttctt ctgtgattag
    12421 ctgacggata ttgtttctgt tcgtttcagc gatttgctgg acgaattctt taggagtcat
    12481 gttttcagca gctttttttt catgataata atcggtcatg tcgtaaatgg caaatgtcgc
    12541 tccatttagt ggcaccgtct gtgaaatgat atctgctgtt tcccctgctt cctcagagat
    12601 agccaagcca tcattttcat ggtattcaaa ttgatcgtta taatcgatat ctcgaatcat
    12661 ccgtttatgc aacacgaatt ccacgacatc ttcccctgat tcttctgccg acatcgcatg
    12721 tggaagaagg actgctgcaa gcggtagtaa aacaagtaat tgaagcatca aacacaacag
    12781 ctttttcatt accttgctcc ctccttttta gattgtctga caaacaaacc ataggctgct
    12841 cctgcaagcg ccatgaagaa tgcagcaagc aggatataga ataatcgtcc ggatcctcct
    12901 gtagcaggca acggattttc aggatcgttc ccgacactaa gctgtaatct gattcgattt
    12961 gtctccaaaa gttcatattc taactcttgc tgtagatcag gcgtctctgc ttcttcgttt
    13021 ggataatacg aaatctcaac ttttagtgta cccgcttctt ttcctggaac tacccgatca
    13081 ttttctatgt caggttcttc tcgataacta atttctaaaa taaagtaacc tggaagtttt
    13141 ctatagctgt caggtgactt cacttccttg atccgataga ccccttccaa caagtctgaa
    13201 gcattgaata gggaagaatc gtttggatct ggtgccaagc ctccctcgat gatttcatac
    13261 tctcctgcac tattttgttt ctcaattgaa aattctgcgc cttcaagacg tcggctattc
    13321 atactgtcaa ttttcaaaag ttccaaatcg attggcgcta gttcatcttc taaggttact
    13381 tgtagtacac catcgatgat ttcatagcct tccggcaagg gagcagtttc gtcttcgatg
    13441 accgtatctt caatgataaa cttaccttct tcattcagtg caaactggaa cacttgatca
    13501 gatagccgat acccatttgg tgcgacagat tccgagacct catattcacc aatagacaga
    13561 tgcagaggtt ggtcgtaatt taaatcgaca tacttttcta ctcctacggc acgagaatag
    13621 aagtatccga tcccaggcaa acgtttcgat tcttctggtt ctaacggatt accagtgtat
    13681 gctcgataca gcgggaagga agaatccccc actttcctga tatcgaaacc tgcaccatct
    13741 aatgtatggc cttcatggtc taattttcta actcggatct cccgataatc aaacgtattg
    13801 taagcagtga atgctaccca taaacgatcc tcttcatctg ttgtatacgt gagatattgc
    13861 caattttctt cacctgtttg cttgagttgg atagtcccta tagcattatc gtaaagtcgc
    13921 aagatccatg tgtcattttc atcaggttct ttgaaacctt ctgggttctg gctctcaatg
    13981 attttgtatt ctgcatagtt ggtagtttct tcactatcct tataaacaaa tgaatctggc
    14041 tctccgattg gatgaataac tttctcacca tccacgatta catatttccc gtcttcatct
    14101 actgaataga acgtgagtct ccctttctct tcctctactt cgttcacacc agaaagccct
    14161 ttcgctactg gatatccgat ttccagtccg ttaccatctg tttcataaag ttcaaactct
    14221 gcgccattga ttggcatatt actgccttca attagtttat tgatattcat gtggattggc
    14281 ttgaattcat ttcgcatttc cagtttgaca tacaactcat catactctgt gccttctatg
    14341 ttaggctctt gtacaacaga aagcttgtga tattctcctt cataatagga attcggatct
    14401 ttaccttccg gtccgccgac tctcgaacca gatgtatatt catctacaag ctcgtagtga
    14461 cctaacatct catcttcgtt ggctgcatat tttttgattt ggaattgata cgtctcatct
    14521 actaactgat aacgtggtgg tccagcgatc tctctgatcc aaaatatgtc gctgactgct
    14581 ccagtttcat ctcctaaaat cggcatcttc gtttcaaaga tcgctattcc gtccgtggta
    14641 gttttacttg tttcgattgg ttcggcttcc ccactctctg gattttggtc atataatgca
    14701 aattcgactc cagccaacgg ctcgccattt tgacccttct tgctgacttg gaaattacgg
    14761 cctttatgtt cgtaacgaat ggaagaagat gggaaataca tccgtccagt agtgatatca
    14821 ttctcataat cctccaggtt ctgaatatag gccatattgt tcactgtgca aaaatttccg
    14881 tcttgagctc ccgcatcaag ttttacttgg tacttgatcc tgaccatttc cccttcacct
    14941 aaagaaatcg gagaaaattt ataagcttgg ttttcccgtc cgacatacgt tgtcggagtc
    15001 gccactactt ctggtggggc ttgtccatga cgttcttcat cccatatttc tggctcttgg
    15061 tacttcatgc cgttttctcc tggatctaga tggtaaaact gaatatctgc cgatctgcca
    15121 gctccaaatg gtgagacatt aaaaccagtt tcatcataaa gtgtggcttg ctggatcgtt
    15181 ctcttgaagg tagaagagat atcctccaag gctgtaacaa tgtcattctt gttgttcgca
    15241 ttgtaatatc gcggtgttac gccatcttct tctaaatcag caatattttt caatacattt
    15301 cgtccaatag catctagtcg ttgtctcccg ctaacgtttc catcgattcc taaaccaatg
    15361 gagaagatac ttggcgggtt ctcttgatac ttgtttttca gccaatgatg ataagcaact
    15421 gtgttgatcg cagatgactt ttcttgcgaa gtaggactgc cattcgtatt gttattagaa
    15481 gaaccatcac caacccagtg agtcgcttta ttatctcctt cttttacctc tccataacga
    15541 tagtgtacat ttacttcatc ttctggacgg ttaaagtcag atgcataggt aactggatga
    15601 gtaaaccctg cattagaagt attcccagaa aactcctcaa aatttctgaa caaaacgtca
    15661 ttatcttcag caatcttatc ttccatcaca gtccagttgc tccaagctcc attagtgctc
    15721 gtacgataac ttgactgaat cggtgcataa ctgaaggtcg gtgtcccatc tcccacaacg
    15781 attaggattt tttctggatt tctattttct ccgccattgt ctttatacaa tgtttcatag
    15841 ccatttttaa gccctagtgt aagcggagtt cctccgattg gtgtacgatt taatgctgta
    15901 ttctcacttc ccgtcaaacg attgatatca tttgtcaatg gaaagatgtc cgaactgatt
    15961 tgctcatggt tattgatagc tgtactatta tggtaaaaat tcaccatacc gattcgaata
    16021 tccagactcg ggtcagagag cagatcttta ctcatttcgt ttactgcctc aatcaacgca
    16081 gcatttttag tttgactatt ggtcccagcg gttaattcac tcatactcgc tgacttatct
    16141 agaacaaaaa cgatatcgat tggactgatt tcctttttct cgcccccgat gacatctaga
    16201 tagacattgt aaagggttgt tgcatcttca ggatgtagat cagatgctgt gctgcttggc
    16261 agaacaggtt ctacccattt tttgatgtac gccccgttat aatccaagta actgttttca
    16321 aaattccgtt catttcccca aagctgaacg gtttgagctg gaacgtttct atcttcttcg
    16381 cctgcagttg atccattatt agtagcatag tcgtaatttc gccagttcgc tcccccgttt
    16441 gtataatcac tatcatcgat caagttctct ccgtcatatg gcgagccttt gtctccttga
    16501 tagcgttcat tgctttgtgt ccaatttcct aacacttttg tatagtcatt cgttgtaaac
    16561 ttcgggtagc gatgctgttc gttttcaact tctccgctag gatagatata ttcatagggg
    16621 tcttgcgtag ctgttggccc aagacgctcc aaaataccgt tgaataactg gcgttgaatg
    16681 cgctggagtg cttgaccgct gggtacgatt ggttcgtcca gcttttccat ctcattttct
    16741 tcgctacgtt gaatttcagc ggaatcttct gtatcagttt cattttcttg taattcttgg
    16801 ttatctattc tttcatcaac caccacttga agaggtagtt acccttcgtt cacatcgggg
    16861 atcttttctg tttcaaaaat caatgtgccg gtttctgctt cttttgaata aacttttccg
    16921 acataccatt cttgaccatc gatcgtctcg acttttaggt cttctccatc ttcatcatag
    16981 gaggatagac ctgttccacg aacgtttttt acggtaccaa tcccggcggc tgccgcatcg
    17041 attgctaaac gtattctacc ttcattggca ctttcctttt tttcaaaagc cagatgccat
    17101 tcaagggttt cttctttttc aatatacttc ccttcaattt ttgcatagtc ctcatctaag
    17161 aatacctcat cctcctttgt ttctgttgac tcagcagcta catccagggt cgtcatatga
    17221 tagactgact ggaaatatgg tccaaatagc aaactgacag ttactaactg caaaagcttc
    17281 aattttaacc ctttcacatc cttatactcc tttcaaaaat atttgtcttc tttcacaaca
    17341 atcaacaaaa caatgcccat ctaattataa tttaatttaa ctttaatttt aaatcaaatg
    17401 atatcctttt tagttaaaaa acaccaatta tacaacattt attattaaaa ttaaattata
    17461 aaattttata acgttctcat ttaacaaaac ttaagttatt aagacaaatg aataaacaac
    17521 tacgctttcc tcgaaacaaa aaaataaagc acaaatgcgc atttacgcac tcatgcttta
    17581 ttcgtacaat taattcagat aacggcagcg cataggatgc caataacact tcctaaaata
    17641 gctcctccta aaatgtcagt aggataatgt aaaagtaaaa aaatcctcga ataagcgatc
    17701 aaacaagcaa ataaaaaggc taatattcct gcaactggac ttaattcgaa caacgcagct
    17761 actgataaaa aggctagcgc tgtatgtcct gaaggaaaag aagaagtctt cggtttactt
    17821 gtgtaaagga caagccgacg atttttttca taaggtcttt tccgtcttgt cgtttttttg
    17881 ataaaaagca aaccaacaaa aaaatagatc aaactgccga taagaatggc tagaccatat
    17941 tctctagtat caggtatcaa gactaaaaca gcagcaagga gcaaccaaat aaaaccacca
    18001 ttagagatat tactgataaa tttcaaaaaa ttgatttttc gactatccgt tttccgttgc
    18061 ttggcgaact tgttgataat actatcatcg attttagcaa tcaaacgcaa catgttattc
    18121 ctccttttta agaacctttt cttgcgtacg atggataaaa agcaggactt gaaaataaaa
    18181 caagaaactg aaacctaata aagcaaaata gattggtcct gcaaaccaga atgcgacaag
    18241 aaggatcaac gtgcctgcca aatagaaaag cgcgcttttg aaatcattaa aaaacaagaa
    18301 aaatgcagta atccaagaag cttctttttg ttccagttga agcaagattt tgtaactaaa
    18361 gagaagcgcg cttaatagaa gcaaaaacaa cgtagtatac atcaatgtat agccaattcc
    18421 cccaccccaa tagcggaaaa tctgataatc gatcaataga agaagaaaat aaacacttgc
    18481 taaactatct tgctttccat aaagagagaa gttctcacga aactttttcc agaatagtga
    18541 accgagcttt ttctcttcat tttttttgta atgataaatc atatacagaa ctgttcgact
    18601 tgcagttcct aatgtgaaaa caggcaagac gcacaggaac catagtagct gtaaatggat
    18661 aagacgtgga atccattcaa tgatttctaa gaaataatca ttggcttttt taccaatcga
    18721 tcgattcatc atccttttga acctcctgtc aaatccatcc cttcaatgaa ataacgttgt
    18781 gcaaaaaaga acagcaaaat cgtcgggatc aagacaagtg ttgctcctgc catcagataa
    18841 ttccattgtg tcgttgcttg gttctgaaaa acttgcaagc caatctgtaa cgtgtatttt
    18901 tcttgatctt ggatatataa cagaggacct aagaaatcat tccaagctgc gttgaaggaa
    18961 ttgatcgcaa tggtaatcaa ggcaggtttc gtcaatggaa gcatcaaatg actccaaata
    19021 tacaaatgat tcgctccgtc gatttcagca gcttcgatca attcattatt gatcgataag
    19081 taaaattgac gcatcagaaa tatattgaac gcattgccga agaacgatgg aacgatcagg
    19141 ggcaaataag tacctaccca gccgatcttg gagaataata catattgagg gatcatcgtt
    19201 acaaaccccg ggatcatcat cgtagaaaga accaaagcaa acatcagctt tttcccagga
    19261 aaatcaagct tcgcaaatcc ataagcaata aaagaatttg aaaggacatt accgatcact
    19321 actagcacag tgatgaataa tgtatttctt gcatagcgcc aaaaaggaaa ggcggcaatc
    19381 gtatccagat agttttccca tacgattttt tctgggaaaa aggtcggagg ataacgaacg
    19441 atttcttcca ttggtttcaa tgaagtaaac accatccaaa gcaatggaat gatcaaaatg
    19501 attcctatta ctgtcatgag gacataactt agtatttttt ttgtttgccg attcacactg
    19561 gtctttttga aataatccat catttgccgt cacctccaga ataatagacc cacttaggtg
    19621 caagcttcaa attgacaaac gtcagaacca acacgatcag aaacaggatc attgacacag
    19681 ccatcgcata acccatatca aaagctacga acgccttgtt ccacatatgc agattataaa
    19741 aaagcaaaga atttgcaggt ccgcctgttc catttttcgt catgacataa gcttcttgaa
    19801 aaatttggaa agaaccgatc gtagaggtga tcacatcgta aaaaataata ggagtgatta
    19861 atggcaaagt aatacttttg aactttcccc aaacgcctgc tccatcgatt tctgctgatt
    19921 catataaaga tctaggaaca ttttgtaatg tagctaagta aagtagcatt gctcctccag
    19981 aactccatat tttcatcaaa atcaacgcag gtttcgtcca ttgtggatca aacagccaag
    20041 ctggtccagg gatatggaac cagcccagaa atgtgttgat caatcctgca gatggagaaa
    20101 gcagctgcat ccataagatg tagactgcta ctcctgataa gactgccggt aaatagaaag
    20161 ctgtacggaa tacactgatt cctttgattt tttgattgag tactgtggct aaaaacacac
    20221 tgaaaatcgt cgtcagcggt acattgaaga tgacgaaata aacggtgttg tataacgatt
    20281 tccaaaataa atcatcgtga acgaacattc ttttgaaatt tgctagacca atgaaattca
    20341 tcttggatgt caaattataa tcggtgaaac taccaataac tgaaaaaagc ataggcccta
    20401 gcataaatac caagaacccg ataataaaag gcgagataaa taaataggcc catcttgctt
    20461 cttttttctt tcggatagat aaacgcttca aattttcttg cctcctctgt acctagacag
    20521 tcaaaaatgg attattgatt ttgcttgact aagttttcta ctgctttttg tgcatctgcc
    20581 aatccttctt ttggtgattt tgttcctaaa agaatctggt caatctgttc attcactaat
    20641 gtcgtgtaat ccggagcatc taaaggaact ggtgtgatca ccgtattttt aaagttttcg
    20701 tccgccattt gatagatcat ttttccttta tccgttaggt tgtcattatt cactaaattc
    20761 tcattggctg tcttgctcgc catgatatca aaactttttt cgccgaattt ttcttgtact
    20821 tctggagaag aaagatattt gatgaattca taagaggcct caggatcttt tgctccgtat
    20881 ggtacttcca agacgaatcc gccaccccac gaccaatggc ctgaaccttc ttctttttct
    20941 gggagctgca tcacgccaaa atcaaaatca tccggtgcat tttccatcaa actagagtaa
    21001 taattgatat tttgggcacg catggctact aatccggaaa taaatggatc agatacacca
    21061 gacccaaatt cggcttctaa tttattgatc gtatttttcc cataataatc ttgccagtct
    21121 tggatccact ccaaggcttc cactttattt ttagtatcaa tcttgacttt ttcatctttg
    21181 tcaaaccaac tagtcccgtt atctgcgttt agcgcccata catcagcccc taaattccat
    21241 aatggataaa aaccgatgcg tgtaaattct tttccttctt ttttatctag tttacgtgct
    21301 gtttcttcta attcatccca agttgtcggt agatcttgtt cactgattcc agcttcttta
    21361 aataactttt tattataaaa aatgacttgt gtatctgtat tgaatgggat cgcataagga
    21421 tcaccttcat attctactgt atcccaaagc tgcggataaa aatccttaga agtgtctttt
    21481 tctacatatt tggagagatt agttgcttgc tgtgcttctg ctctttgggc aacggaattt
    21541 atgtcctgta caataacatc gggtgcattt ccagctgtta ttgcagataa agatttagtc
    21601 cagatgtcac cccatggctg atacttataa tttacatgga tctcgttttg tgattgattg
    21661 aaatcctcaa tgatttcttc gatagcttct tttcgtgcac cggatcccca aaaggaccag
    21721 aaatcaatat tttttcttcc atcacttgtt ttttcagaag aatttgctgc acttgaactg
    21781 gcatcgcttg cattacttga tccgcatcct cctaataaaa acaatgctga acttgccagc
    21841 aaccctgtaa acaataattt tttcatattt tacctccaaa ttttaatgta accgatgccg
    21901 gttttaatat aacgatatca ttttgttctg aaaataacaa tttataaggt atgattctaa
    21961 aaaaattatt aatgatacca atactttata taattcgcga gcgctttctt tgaatttttt
    22021 aatctttcgt agcagaatga gaatgtatta aaaatagatt aggaggaatt ttgatgttta
    22081 gacaccagaa agaattgcag tttgaagcaa aaccagatcg tccgaatcca ttaatcgcga
    22141 aatatctgca ggagctgatc ggcggccaat atggcgagat gagtgtagct atgcagtacc
    22201 tgttccaagg ctggagctgc cgaggagaag aaaaatataa agatatgctg atggacattg
    22261 caacagaaga aatcggccac gtggaaatgt tggcgacaat ggttgctcgt ttattagagg
    22321 gtgcgcctgt tgaagatcaa gaagcagcga tgcaaaaaga tccaacaatc ggtgccatta
    22381 tctctggaat gaatccacag cacgcgatcg tagctggctt aggacctcgt cctgctgaca
    22441 gcgtgggcaa tccatggagc ggtgcctata tcattgcgag tggcaacttg ttagcagact
    22501 ttagagctaa tttaaatgcc gaatcacaag gaagacttca agtagcacgt atttacgaaa
    22561 tgatcgatga tcgtggcgta aaagatatgc tgtctgttct ccttgcaaga gatagctatc
    22621 atcaaaatct atgggaatgt gcagtgaaag aattagaaga aaaagaaggt tcaatcttag
    22681 tcccaagtac tttcccgcgt gacaaagaac gaaaagacat tgcttatgac ttctataact
    22741 tctcagaggg agaccaaagt agtgaaggtt cttgggctag tggcaaagca ctggatggcg
    22801 aaggcgaata tcaatggttg aaagaaccta agatcgaagg cgctgcacca aaattagaac
    22861 cagtaacacc aaaaatgtat gggacacctc cattcaagaa ataaatatct acccgtagaa
    22921 acacccgttt tttgttccac acgctttgtg agcaaaactg actaaagtca ttaatcataa
    22981 ccacccttca aaagggtggt tttctctaga gctataagct caaatcaccg gccagcgcct
    23041 aaagacgctg gctttcatat tttatgttca agccatattg cctttgccag ttttgcccac
    23101 ctcttaaaag gtttatgtac tactccttag cccttaaaag gatcgtctta ctctcgtaca
    23161 ctcagcttat ctaacgcact atcatgtttt tcttgttctt gaatgtactt tttgatggtc
    23221 gcttcatttt gtcctacttt tgtcacatag tatccttcca cccaaaagtg tcgataccca
    23281 aatttatatt ttagatttgc acaatctctt gatgatctcc tgaatattgg ctcgatattg
    23341 attataaatt atttttcttc tatactttgg tgtgaataca atgtggtatt tacacatcta
    23401 ctttgtacgg gctaaactat ttccctttat tgctccaccc gcatagcaag tggttttgta
    23461 tttcaatcgc tcggcgcgct caattaggtc taaagacaat aaatctaaaa acccgctgct
    23521 tcactgacag aaacaacggg ttttcagaaa aaaatgaaat gaaaaagatc tcttacggca
    23581 atctatttta tttttttgat tttttataaa tggaaaatgc ttcaagaagt ccaagaaata
    23641 aagccgtata aaaacaagaa cctatgaaat ctttatttat tagatattca acagaaatcc
    23701 cgataacact agccaacaat atatttatca gaagtgtaaa ataaggatgc tttttataga
    23761 atagaactag tgttgttttc atagactctc ctttcttcat atttccaatt aatcacaaat
    23821 tcacggcatt actagaaaaa ttaaaggggc gcagaagtgg aaaaatactc ttcgactttc
    23881 cctacaaacc aggccatctt gtgtttaata actataccaa atctaaggta cctctaaatc
    23941 taaattccat ttgtggcggt gacctccaat ttttaactct tctatctccc atccagtata
    24001 cataaccttg atacttcgac cacttatata tcgaacacac aaatacctat ccattgcagg
    24061 agtactacct aacttagttg ctacttgcat ctaaataaca gctgaaaaga taggacttac
    24121 tcttagtaaa gtatctgaac tattaatttt taaactatca tttttatcct caactacatg
    24181 cacatctgtt gcaacttcac tttctgtctc atccagataa atgattaagg aatcgggaat
    24241 tgcaatatct tcagctgacg ctggaatagt tgagctaaat tagtcatcat atctttatta
    24301 taaaataacc aacagcaaaa aatacaatga aaaacaaact t
//
LOCUS       DAIGSZ010000043        23829 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.043, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000043 DAIGSZ010000000
VERSION     DAIGSZ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.043"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(53..787)
                     /locus_tag="NOB31_001808"
     CDS             complement(53..787)
                     /locus_tag="NOB31_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCI0974013.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="NOB31_001809"
     CDS             1114..1524
                     /locus_tag="NOB31_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HCI0974014.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="NOB31_001810"
     CDS             1517..2218
                     /locus_tag="NOB31_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HCI0974015.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="NOB31_001811"
     CDS             2218..3804
                     /locus_tag="NOB31_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0974016.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="NOB31_001812"
     CDS             3823..4044
                     /locus_tag="NOB31_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HCI0974017.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="NOB31_001813"
     CDS             4041..4802
                     /locus_tag="NOB31_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HCI0974018.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="NOB31_001814"
     CDS             5182..5691
                     /locus_tag="NOB31_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCI0974019.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="NOB31_001815"
     CDS             complement(5766..6305)
                     /locus_tag="NOB31_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HCI0974020.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="NOB31_001816"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="NOB31_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HCI0974021.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="NOB31_001817"
     CDS             7318..8169
                     /locus_tag="NOB31_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HCI0974022.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="NOB31_001818"
     CDS             8197..8832
                     /locus_tag="NOB31_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HCI0974023.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="NOB31_001819"
     CDS             8852..9625
                     /locus_tag="NOB31_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0974024.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="NOB31_001820"
     CDS             10033..10830
                     /locus_tag="NOB31_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HCI0974025.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="NOB31_001821"
     CDS             10808..11221
                     /locus_tag="NOB31_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCI0974026.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="NOB31_001822"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="NOB31_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCI0974027.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="NOB31_001823"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="NOB31_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HCI0974028.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="NOB31_001824"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="NOB31_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HCI0974029.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="NOB31_001825"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="NOB31_001825"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HCI0974030.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="NOB31_001826"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="NOB31_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HCI0974031.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="NOB31_001827"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="NOB31_001827"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HCI0974032.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="NOB31_001828"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="NOB31_001828"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HCI0974033.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="NOB31_001829"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="NOB31_001829"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HCI0974034.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="NOB31_001830"
     CDS             21905..22483
                     /locus_tag="NOB31_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0974035.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="NOB31_001831"
     CDS             22535..23017
                     /locus_tag="NOB31_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HCI0974036.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="NOB31_001832"
     CDS             23134..23508
                     /locus_tag="NOB31_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974037.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7780 a         4286 c         5116 g         6647 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcgtg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtttt
//
LOCUS       DAIGSZ010000044        23039 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.044, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000044 DAIGSZ010000000
VERSION     DAIGSZ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.044"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..2569)
                     /locus_tag="NOB31_001833"
     CDS             complement(<1..2569)
                     /locus_tag="NOB31_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974038.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIPE
                     "
     gene            complement(2791..3675)
                     /locus_tag="NOB31_001834"
     CDS             complement(2791..3675)
                     /locus_tag="NOB31_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCI0974039.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(3770..4207)
                     /locus_tag="NOB31_001835"
     CDS             complement(3770..4207)
                     /locus_tag="NOB31_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974040.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(4424..5335)
                     /locus_tag="NOB31_001836"
     CDS             complement(4424..5335)
                     /locus_tag="NOB31_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCI0974041.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(5712..6350)
                     /locus_tag="NOB31_001837"
     CDS             complement(5712..6350)
                     /locus_tag="NOB31_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974042.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(6354..7124)
                     /locus_tag="NOB31_001838"
     CDS             complement(6354..7124)
                     /locus_tag="NOB31_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HCI0974043.1"
                     /translation="MIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQE
                     ISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSTYWERNILSGEIYPPLK
                     IKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFS
                     FFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIER
                     EPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            complement(7542..7958)
                     /locus_tag="NOB31_001839"
     CDS             complement(7542..7958)
                     /locus_tag="NOB31_001839"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974044.1"
                     /translation="MMTREKEAYERFILLFVERFNQAFHTDYATNIFEDFENSYSYSV
                     ISSTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNGFSLHQVLWCLLGKKKI
                     IITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGI"
     gene            complement(8009..8390)
                     /locus_tag="NOB31_001840"
                     /pseudo
     CDS             complement(8009..8390)
                     /locus_tag="NOB31_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8516..9181
                     /locus_tag="NOB31_001841"
     CDS             8516..9181
                     /locus_tag="NOB31_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0974045.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(9578..11611)
                     /gene="brxL"
                     /locus_tag="NOB31_001842"
     CDS             complement(9578..11611)
                     /gene="brxL"
                     /locus_tag="NOB31_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HCI0974046.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(11729..14251)
                     /gene="pglZ"
                     /locus_tag="NOB31_001843"
     CDS             complement(11729..14251)
                     /gene="pglZ"
                     /locus_tag="NOB31_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HCI0974047.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(14367..17999)
                     /gene="pglX"
                     /locus_tag="NOB31_001844"
     CDS             complement(14367..17999)
                     /gene="pglX"
                     /locus_tag="NOB31_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HCI0974048.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVT
                     SERKLKKIREKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLV
                     NQFNTLKSNEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCI
                     FGRYSLDEDGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVE
                     ITFGKETLEENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGK
                     QNGFKALMYLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTK
                     EIVKIQKQLKEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKG
                     VKEPKK"
     gene            complement(18063..21734)
                     /gene="brxC"
                     /locus_tag="NOB31_001845"
     CDS             complement(18063..21734)
                     /gene="brxC"
                     /locus_tag="NOB31_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HCI0974049.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(21759..22334)
                     /locus_tag="NOB31_001846"
     CDS             complement(21759..22334)
                     /locus_tag="NOB31_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HCI0974050.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(22334..22933)
                     /locus_tag="NOB31_001847"
     CDS             complement(22334..22933)
                     /locus_tag="NOB31_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HCI0974051.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         6993 a         4532 c         3344 g         8170 t
ORIGIN      
        1 tttctgggat agaaagaaca aatttacctg tatcatcaat agttgtttcg gacaaaacag
       61 cttgattttt tttcaatgaa accaaagctc ctgcttcgcc tgtacctgtg attgagcgag
      121 aagctgcatt gatcaatgtg gtacttaatt tagcaggctc aggaggaatc acatcgactg
      181 tcgttttggc agagtccagt tctgtcactt cttggccgcc tcttactttt ttagcagcaa
      241 ctatttgcac ttgatccccc gttgttagtc tttcttcgtt gggtacttga acctcaaaca
      301 aaccgccttg ttcgccttct ccccacggat tatatcctgt cccttcattt tcatctgttt
      361 gtccttgtgt gagagcagta atttctacag gtgatttcgt cgtatctgca taagtaatac
      421 gtaaagtcac ttctacttcg cctgtccaag catctcttgg ctttgcctcg acaccttcgg
      481 gaacaacgac atgcccatag atttttttat ctgcattcgt tggtactctt aaggattcaa
      541 tcatcggaag ctggttattg gcactgattc gattataatt tttcattccg gcacctgtct
      601 gagcaaattc atttgttaaa cctgcactag ggcttgatac aaaattacct aagtcggttc
      661 cattgatcga taagtctgtc atatcagaaa aataatccgg atctttttca aagttatcga
      721 acgttactcc tgcctttcgc cataaagcaa tttctgaatg agcgatcttc aaagaagaat
      781 cgccatttcc ttgaaatacc cagccaccta tgccattagt ctcgcttccg atccgtttgt
      841 tttggaaatc gaaataggta ggagattcta agtctacatt caacacatcc ccactgatga
      901 tgccagtctt atcttcccca gttttcccga ccatgactaa ataagttttt tcgccagcca
      961 taaagttcaa atcaatatct ccagttgtat ctacggtagc tccggaatct gcgcgtatat
     1021 cgatatttga tttttctcca gtaaccgtaa aatcagctga ccctggactt tctagaaaac
     1081 cagaagcgtc ataaaattgg atcgcttggt ttccttgatt gagtctgttc acataagatt
     1141 tgccatcccc tgcatttctt accttcaatg agcctccatt agttactgtt agtttttgcg
     1201 taccgttctc aaaacgaact gcgctagaac gaccactttg cttatcaata tcgatgactg
     1261 atccggctcc ttctacgatc aaagaaagtc ctttccctac aaaacgcatc ccattgtttc
     1321 caggttggtc gccatctcca gccattttga ccgagatttg tccaccactt gatacatgga
     1381 tttgactaga atctccttgc aggcgaaatc cgccagtagt cgctgtattg attgtgattt
     1441 tcccatcatt cgacacagcg actcttgatc ctgagcctct catttggata attccgcgat
     1501 tgttgtcgtt ggtaatattg atctttgtat ttaccgaaaa ttcacttcct gagccactga
     1561 ctttaaatgt gacattcccg ggtagcgtat cgacagcctc tccttcatcg ctgacgccat
     1621 ctgcccgatc atagtcaaga gagacctttg aaccactcaa gatatggagt cctggtgctg
     1681 tttttccact gcccgtctca tcacctgaat ctagaaaacc atagaatttt cctagatatg
     1741 gtccataaag ctgactacca ttgattacat ttagctgata gcttctacaa aaataagctt
     1801 tacccggagc ggcattcatc ccttctttca ctggttggac atccaataca ccggaaacac
     1861 catctaatgt gacagttgca cgaggggcgt aaatcaggcc taatttagaa ccatcatata
     1921 agtcaagtgt cccggtaaat tttatttctc ccgtaaaatg atatctgttt ccccaaaaat
     1981 cggacatata agcaatgata atggcatttc catcgatatt tggtatcaac ccacctggat
     2041 gagctgccgt tcctttaaaa ttctgaaact cgatcgactg aggtgtctca ttgatataga
     2101 tgtgatgtgt gccgaaatta tgagcaagtc cgccaaaatc gataacgata tctcgcttga
     2161 tctccaattc cctgtctaaa gtcaaaggct gagttaaacg aatcttagct actgattcgt
     2221 ctgcgagaag ctgcgtcagt tcttctgttg tggcagcttc gctgtaccca tccgctgaaa
     2281 caactctaac ctgtacctct tcactgctat cagacgtttg ttcagctact tctgaggtct
     2341 cacttgtctt attttcttct tgccttgtat tagaagtagg cgcctcactt tgggattctg
     2401 tagtttcaga agtaattgat tcttctgaaa aagtagtctt gtcaaaactt tgattctctg
     2461 attgcgttga ttcgcttgtt ttctctacat cggcaaaaac ggatgtcacc atcaagagag
     2521 ggaagacaaa caaaatcgac gcaatcagct tttttacata ttgattcatt ctccaccatc
     2581 ctctctgacg ttttgacaat tttattttaa cgttttaatt tatttgtaat tgtactttca
     2641 tatttaaaat atgtattttt atggcaaatt tttctgttag gtgaaaattt cttttttgta
     2701 caaaaaaagg ctgtgacaaa agtcttgtca cagtccctta ttccgaacaa ccgatgtcct
     2761 cctgacaact cttcggtcac aacctccatt ttaacaataa acctgtaaat gtgagggtaa
     2821 cactttgatt gtcacaggta atttatcccc ttcatctcca tcaacattcg tcgtcaattc
     2881 ttcctcatca gctaatgaca caactaattg ctcacaagta agataggcta gatttttcgt
     2941 agattcatct actcctttta ataggtctgg caatgtttta agcgtatcga tcaaagaaga
     3001 atcttttaaa taaaccaaat ggagcttacc atcatccact tttgcatttg gaagtaatgt
     3061 ttcaaaaccg cctactgagt tagttagtcc tatcagcaag atactgctct caatttcttc
     3121 cttctttcca tcaacttcta cgtgaaacga gtaggattgt gtggaagcta actgtttgat
     3181 tcctgacatg aaataagcta gttttccaaa tttcgtcttc ttctccgcat ctacatcatt
     3241 gattgcttca gggatagagc caattgcgac gacattcata aaatagtcgt catttatttt
     3301 tccaatatcc aatggcttga ctgattcaat cgaaaaatga ttgatcgctt cctcaggttc
     3361 tagcggtatc cctaatgctc gagccaagtc attcaccgta cccaatggga aaaatccgaa
     3421 atttggccga tgttcttgtt cagcgattcc actgattcct tcgttgactg ttccatctcc
     3481 gcccatgaca aacacactat gatacccttc cgtagccgct tcgcgagtaa agttttttgc
     3541 atcccctgct ttttttgtat gcaagacgac cacttcatca aacaccgatt ccaattttgc
     3601 tatcgctaat tgctcaaatt cctttgcttg ttcaccgcct gaactggggt ttaccactaa
     3661 taaaactttt ttcatcactt tctttccctt ctgattgatt tctttaatat aacgatagca
     3721 taaagaaaaa aattaggctg tgatgaagta ctgttcatga aacattcatt tattttttga
     3781 caagataaaa tacccatact atgaaactga ggaaaattaa aacaatgata taggaaataa
     3841 aagaaaatga taggcattgt atacctaata aagtaaaaat cttaggtggc agataaaaac
     3901 acaaaaatag caagagaatg taatagcgtt tcttccactt tttgttatca gaccttatag
     3961 cgatcagagg aataccaaat gcataactga aaaactcttg atgtactgtt aatatgtcac
     4021 gaccttgaat aataaatgca acaatccccg ctataattag tgtgcctaat accaaaacgg
     4081 aaaattgatg aatatatttt atatacaaat gatccattgt acttcctgcc tttttatttg
     4141 tgagaaaaac aaatccgtat acgtgaataa cttctagaaa taaaagaaat ttgcaaaacc
     4201 actccattta tctacttcta cgtgcatttt ttaatatcgt tttctttatt taagattata
     4261 cagaaaaata tctagggtgg ctggattcta agtaaaaaaa atttttaaaa taaaaagaac
     4321 taaatcaagt aataattaaa ctactgttga tttagttcta ataaaaagat ttagatgaac
     4381 agttttattg atttaaatag ttcatatttt ttatttatac cgcttattta ctacttgctg
     4441 tactagaatc tgaagtgaat gtactcaaaa cattttcaaa gtctttgtct ttgattttta
     4501 cattagcgtc tttcaatact tcgccaatta ctttattctg gaaggtactg tcacttaatt
     4561 ttgtgtctgt tgcaatttct ttcaattctt ttttgtattt atccatgtcg ttgcctttgt
     4621 tttggttttt caccatttta accacataat attccgtagt ataagttgaa gcattggtag
     4681 aagtgatcac atcagaaact tgaccatctt tcaacttaaa ggctgcttct ttgacttctg
     4741 ccggaaccgt tgtagtagtg gaatcaaatt tcacttttcc gccatcttct tttgtcgtag
     4801 tatcagttga cttgtctttg gctaatttag agaaatcgtc tcccttatca gcagctttct
     4861 tcacatcttt tgcatcatct tcacttgcta cttggataat ttgagcttcc acttctggat
     4921 ggaaagattc ccaagccgtt tttaaatctt catcggtcaa tttgatatgt ttctttagac
     4981 cttcttgaaa ggctagactt tgtttgatac tgtctttgaa tgtttgttct gtgtaacctg
     5041 cagatttcaa ttgtgaatca aatgaatcac ccaattgttt ctttgtttga tcatattggg
     5101 aatcgatttc tttggttgat acgtcatctc catatttatc ttcaaatact tgataaacga
     5161 tcaactgttg cacagcggaa tctgctcctt gcattttttt caagctatcc attacttctt
     5221 gttcgctgat tgtaccgcct ttataactaa cggctgtttt ttcaccggca ttcgtacagc
     5281 ctgacaataa gccagtgcct agtacgatgg caagtgctaa aaatcttttt ttcatttatc
     5341 aattctccta cttttcgttt tttgcgaatt gctaaaaaca aaggtgttca agatgaaaat
     5401 catcaagaac acctttacta atctgctcga tacgtcctga atagatataa ggctacacaa
     5461 tccagaaagt tcgctcagca gaataaatgt caagtagcac atcacacctt aatatactac
     5521 ttcttttgtt accgtttttc aagtctatct tgcgttccgt atttaacgta actaattctt
     5581 agaacaaatg ttatcgattt tgtttttctt cttccgctgt tgggatattc aaatcagaca
     5641 cttttatgtt cgattttcca gacatttttt tgttgttttt attagaaaaa gtttgttttt
     5701 tcatttgttt tctaaagcat gatcttcttg tttcctattt tggtcagata tggatcatgc
     5761 gtgaccacga taactaacgt accttgggaa gcctgttgcg ataagatttc aacgacttgc
     5821 tccttatttc gtttatctaa tgatccagtt ggttcatcgg ctaaaatgat tttgctattc
     5881 ttcaataaga ctctcgcaca ggcgattctt tgcttctcac caccagataa tgtgtagata
     5941 ggcgtactta gcttcttgtt tatatttact tttttcaatg cctcatactt tgctgttcgc
     6001 ttatctgaaa catttaaatt cgaaaacttc aatccaatat ctaaattaaa atcgattgtt
     6061 tcatattcaa tcaacccaaa atcttgaaaa agaaaagaga gggcatttct ttttatcaag
     6121 cgcttctctc ttccagttaa atgttttgtt tcttgattaa ataaataaaa ttgccctgaa
     6181 ctgaattgat cattcaatcc taatatattc aataaagtac ttttccctgc tccgctctct
     6241 ccaactacag tcacaaaatc cccagcatcc gcagtgaaac gatccaaatg aagaatcgtt
     6301 ttgtttcgaa tgattttttt cgcacctttt atcactatca acggctccaa ttgttaacct
     6361 ccattcatca gcaataactg acttttcttt tctgtagaca aaataaaaac aactgaaaga
     6421 ataaaatcaa tgaagctaaa gaaaaaaata ttaaaaagat atttaggctc tctttctata
     6481 agaaaaagga agattacact tgtcgttccc catttgatga ggttcatcat gaagaaatct
     6541 ttatacgttt caaagagcga ataaccactt gaacgaaaga tagcgatttt ccgacaattg
     6601 tagacaaaat atatgcataa catgacatag ctcaacaaga agaaagaaaa gaaagtgagt
     6661 aaaaatatct gtatcaagta atgaaatgat ctgcttaaca ctttgacagc tatctcttca
     6721 gtctgagtat acggaaatga taactgcaag ttatcacgta actgactttc ttcaatcagc
     6781 tcaaataacc tttctttcga caaagagcct atcttgatct ttaacggtgg atagatttct
     6841 ccgctgagaa tatttctttc ccaatacgta ctgtttttca atgtcagtat ttcaacaacc
     6901 ggataatgtt cgatccaggg gatagaagga ataaatgtat aaatgggttg attgtttttt
     6961 ataaatagaa atttcggttc tttttcactg atttcttgat aatattctgt tatttgcgcc
     7021 aggtcatttt ttaaatctgt atgtctatat cgttcaggga tcaatataac agggtgcgtt
     7081 tctttttcgg ttatttggat caaccttcca gagacatcaa tcaaaggaaa tttcttaaga
     7141 taattcagat ttatttttat ccctctgcca aactgttcat tttcttcatt caagtaatct
     7201 gatacattga ctaatatact tccgttttta ttcaaagttt catataattc ctgatcggct
     7261 gctgatgcaa aacgattgga ataaataaaa tccacgtggt ttttcccgat ggttactgga
     7321 taaaatacat gatagtcctc accagcgatt tcttttggtg tttcatggga aacagctaac
     7381 tgtgaagaag aaaaaacgat agttgctaat tcgacattgg caacggtcaa aagaagagaa
     7441 aacaacaatc caaatgtaaa aagaatgtat tggatatagt tgaacgcttc tcttaacgaa
     7501 gcgatttttt caactaataa aagagaaatc aaagagatac cctatattcc gctgaacaag
     7561 aaaacgtaca tctggaacaa ataaagaaat tgctccttat aatacataaa aataaaacca
     7621 ccaatgattc ctgcaattat gaatgtaata atgattttct ttttccccaa taaacaccac
     7681 aatacttgat gtaatgaaaa gccattattc aacaataaac tgatttcttt attcatcaat
     7741 aagaaaaagg atgataacaa aaggaataaa agaatcaatc caatagttaa atacactcga
     7801 taattatata cgtctgtact tgaaataacc gaatacgaat agctattttc aaagtcttca
     7861 aaaatattag tggcataatc agtgtgaaat gcttgattga atcgttccac aaatagtaaa
     7921 atgaaccgtt cataggcttc tttttctctc gtcatcaaga aaaattcacc ttcaaaatct
     7981 tttattttga tcgattcttc aatggacgtt acgcgaaagg aggtattaga atagggtacc
     8041 ttctcgtgag aagatttgac atccccttga taatacaatg tcatttcaag ctttggctgt
     8101 atcttgaagt tccaagatgt atctacttca ttggattcat ttactgtttt tttcatataa
     8161 gaaagctcag tttctgatga gacattttca aataccatga ttagctgctc atattcttct
     8221 tgcccaataa aatgttgtgg caatcgaatc ggagtataag tatctgtttg atggaaaaat
     8281 tcatttgtcc gatagagtac ctgtttattt ataataacca aggcaaaacc actcatgata
     8341 ccggtcacta tgattgtgag taaaactgtg aacttttttt tgattatcac cactctccct
     8401 tacttaaatg attctttgat aaaatcatac cgtttttcat caaaaaaacg tatctatcaa
     8461 atgtataggt catgtagaat aaatctatat actgtagaat cgaaaggaga agaagatgaa
     8521 catcggagaa aaaatacgaa cttaccgcag aaattgtaag cttacgcaaa aagaattagg
     8581 cgaaaaaatc ggtgtttccg ataaaacaat ctctagttgg gaaaattctc gtacaatgcc
     8641 agaccttgaa atgctgtcac ttttacatca gactttaggt ctgccgattg attttccttc
     8701 tattgaatca gctaccgaat caatagaacc aacattgccg gatgaacctc ttgttatcaa
     8761 gaaatcttat tcatcaaaac aacccttctc actcaaaaag acactatctt tctttctgct
     8821 cgtcttttgt ttggtctatc tttttcttat caattatcaa tataaaaatg aaacggttga
     8881 tcgattcaat ccttttttga aaccacaaat cggctatacc acactccctg taggatacgt
     8941 ggaaaattcc atcgaacatt gggtatgtaa tgatatcttt gttcatggta catggctgtc
     9001 ttttcacgct ggagaggtag aaaaaggtaa gaatcatgct gtaatcaaac acaaaggaaa
     9061 acacgtcatg aacgttcgcc tgctcacttg ggaagccatt ccctcagatt accaagaaat
     9121 cctcatccaa gactatgacg atgccttaaa aagaagccct caggagccag ataggcatta
     9181 agtaggagat gaacgtagag atagaaaaaa tcaatgcaca tgatcttatc aaaaaaaaac
     9241 aggggtacaa attaattgaa aaagctttga gatgaaagtt cctaaataaa aaagttcaga
     9301 atgataggta aaaaaatgac taactattct agtattaggc tatttgtatt attcttctgt
     9361 tatttttata tcaaaaaatc cagaaataac taaatatagg tatttctggc ttatagtata
     9421 atatttacgc cacagccccc aatgattctt tttggaatca tgatcaagga cggacataca
     9481 caaaaatatt ttgcccattc gatccgaata gattaacgac taatctagta agtaatatag
     9541 attggtacgt agtcaaacca gcaaatggaa aagttgtcta ttccacccca agggctttaa
     9601 agacagcatc ttccggcgtt tgataaaaaa tcaaattaaa ggtacccatt aattctgggg
     9661 gtacagttcc aatatcagca gcgcttatca taggtacaag tacttttttc gctccggcat
     9721 cttttgctac ttgtaaacag ttagctaaat tatctacctt aatcatagaa ccaccaattg
     9781 taatatcccc taaaataact aaacttggta atacaggttt atttaaggaa actgagcata
     9841 aagctattat agttgataac gataatgttt ttgtcatacc aatgccattc atatcttgaa
     9901 catgaacgac aaaatctttt gtcgtcaaac taatagactg actaacactt ccataattag
     9961 ctcttaaata tcggtatgcc gaatccatcg cttctcttgc tccagcatct gaattgatcc
    10021 cagtacgttc aaactttcca tttcccgaag tcatttgcgt ttccaattta taggtaccta
    10081 attgcccagt tttgccataa gataccgtgt acaaatgccc tggcttccct aacccttctg
    10141 gaatcaaagt tcctccacct tgttcaggaa cagaaacata ctcttctcgc tcttcttcta
    10201 aatcaatgta tgaaaaattg acatcataaa attccattcc accaattttc tttaattgtt
    10261 cttttacacg acgacgcatt tcaagagcaa atcttagtat ttcttcgaca tcactttttt
    10321 caaatctacc atcaggatac aacagtttca tcatcccaga tacaatccga cgaactgcaa
    10381 tcgtatcccg ctgatttaat tgagaaccaa gtttgaaata tttatcaaaa ctatcgccaa
    10441 aactaacttt tcgaagctca cgcatgactt cagaaaaata atctgtaatg aagccatagt
    10501 catttgtaaa aaaatctggt cgatatttag gaatttccca acctggtaaa taacaatgca
    10561 tccgatccaa aaaggctgaa tccgtcccca taacctccgg aaatggctca aataaattcg
    10621 aagttttcaa tattacatca acgctttgat taatatttcc tacaaaagcc attgatgctg
    10681 aagcattctt ttcttctttg cctctagcaa aagatcctga agccatgtaa tctttcatga
    10741 tttgaacgcc atcattatcc ttaaatttaa tcccagcaac ttcgtcaaaa gcaacacagt
    10801 cccacatacc tacaagtccc attgtacgac tagccatatt atagaaaagg tttgctactg
    10861 ttgtttgtcc acctgaaaca aggattgagt ttggtgaaat ttctttatat acatgcgatt
    10921 tacctgtacc acgtggtcct agttcacaga gattaaaatt attttcaatt aatggaataa
    10981 gtcttgctaa atgaagccat tttacccttt tattaaattg tgtaggttcc ataccaatgg
    11041 accgtagaag taagtcaatc cattcatttg tagtaaactc cttgcgagcc atcttgtaag
    11101 cctcaatgtc taaaccaggc atttggattg gatcaacctt ttttgcaata aaagggctat
    11161 tccaacgatc attctcatca taccaatatt ccatcgaaac aatacaccag atccccccac
    11221 ctaataatcg atcaaatttt ttcggatact cttcactaat ttgaacattt tttaatccca
    11281 ggttagagaa ttctgcttca taacaatctt tcttttcatt taaatgtaca gttactttat
    11341 caataactgt ataaccaccc aattcacgaa tttttgcttt tactttttct gcttcatcag
    11401 gacgcacata gtttcgagca agaatatttt taacattttc cacacctttt tcaaccaatg
    11461 tttcatccaa tgacgaagca tacataccaa gtaaatattc caatacataa acaggtacat
    11521 tcgcaccttc tttaattttc tttgttaaat cttttctgac aatctttccg ggaaagaatt
    11581 cagataactt taaaatttcc tgttgttcca ctagaattcc tccatgtgtt cagtcattat
    11641 aatagcaatt aaagtatatc atacttaacc agtaggcttg ataatacaaa agaaaaagta
    11701 tccacaaaaa attgtggata cctcgttttt atatatcaaa atcaaatgat tctgcaaaag
    11761 gattatctat aatgaatttt attcgctcgg tcaaatcatt tttttgattt tttatcacta
    11821 aataataagt atcttcaact gtatatcgac gatttacaaa ttcaaaaaca aatttagtaa
    11881 accgctgatt tgcatcttct gtttttgaat ccgcaacata gatttcttca tttgagatac
    11941 gttcaccata ttcatcttca aaataaagcc agaaagatgc ggggtcataa acatcactaa
    12001 ttgcattttt ttgatagaat tctaacgtgg ttgataatcc tgtaattctg cggttgctag
    12061 tcattaattc aattgctact ggttcctttg cattgctacc tttggctacc gtaatttcta
    12121 gaacagggac tagcatttct tgaatagatg accctccatg aacgtagctt tgtcccccgc
    12181 cagctttctt aaaaatactt gaagtaatcg ggacacaaat gtttctagtg tcatcatttc
    12241 ctaaagaatc tcccaaagag taatttttcg taccaattat ttcgtattct tcttcactaa
    12301 gaataaaacg acgttctaca cgatcttttt catttctaga tggattttca atcttatcta
    12361 cttcttcaac gtggcttctt ttataaataa atccatgatc agccgtaact ataaaacgat
    12421 agatactgcc atcattatgc aagcgattaa taagtcggga aatttcgctt atcgctaaat
    12481 cacaggcctc aaaaactcga ttttcattcg agtgatcacc tgttctatcc acttgatcgt
    12541 gataaatata aatgactgat ttgccattaa atacttctcg tacctcagcc ttattcatct
    12601 taaccacatc atcataattt aaagctacag catttgcatc tcgttgctgg agaatcgcat
    12661 ttcgattgga taaaccattc gtttttttcc catcaatcag tacttctgtt ccttcattgt
    12721 aagttagttg attgtttggt aataaggcgg ctttaccgaa ttcagtaact gaaggtaata
    12781 cagaaagaaa gctagccatg tttgttgaat acttcttttc tctaactaac ttacgttcta
    12841 aattcatccc taactcatat cgaaaagcat ctgaaataat aactacagtt ttaacagagc
    12901 gtttcattac agcttgatta taaaattttc gaatggatgg acgattctta aattcaaaag
    12961 tttgattcca aatttgtcct gattgatcaa gaaacttcga ataatttgct tcaactaatc
    13021 gatacaattg gccatatttt tgcttttctt ctatatgatc actattccaa ataaatttcc
    13081 gataatgcgt atcaacccaa tacatttcct tctcatattg agttagcaaa ttatccatgt
    13141 tcatcggcaa gcacaatctg tttttatcca caagataata agcatgtttc aataattgat
    13201 actcataaat ataatccgat gcgaaatgca ttttttcgcg ctgctttaaa ctatcaaaaa
    13261 ttgtttgtcc tgcaattttc gttgtagtgt cagaagcctt taatcgttct gcataaaaca
    13321 ttaatatttt tgcatgaatc tcagaaaata cgtctgcttc aattagatca tcaatttcta
    13381 tactgtctaa taatccatca ccatcaatag cctgatatac ttttttagat agctgttcaa
    13441 agctttccat gtaacgtgta tcattcataa actgatccat gaaagtaata atgtttgctt
    13501 tcaaatgtag tatttcaaat cctttgaact tcttcggcat ctcttgatca atttgataat
    13561 aaaaatagtt caaataaaga cacatcgtca gcttttccaa tgttggctgg ctatccgtaa
    13621 agccaaattt catttgaata aattcccaaa atttagctgt taactgatac ttatcaagtt
    13681 cccttaaagg attctcccta ctttctgtaa agctttttag aactacacgc agtaaatcat
    13741 ttaatcgaat acttttcgat ttcaacaaaa cagccattat cattaattca atcgtttctg
    13801 atttattaat tgtcatatgc gtactaaatt caccaaaact tctcatgcga tcctttgcat
    13861 taaagaaatt acgatactgt ttaactgtct gatgaaatct aagtggaata gccaattcat
    13921 tcatgataat cgctaagcgg tctgcactaa attcctctga ataattcaat acactcaaca
    13981 aatgattatc ttcatcttta tcatcccaac gaggaaatgg cgcatagatt aaatagttag
    14041 tttcgggatc ttcatattcc aataaacgct tagttttaaa ttgtgcgtcc ttttctaatc
    14101 gatagatttt tgcattttga atgaccaatg agtcaatttc ttcaagaaaa tcctgatttg
    14161 aatcaaacca aaaaatgatt ttcctacatc cataattagg aaaacgttga tttaattttt
    14221 cttcaatttg ttgcgtattt atatctgtca tcaatctcac ctaatcgttc tctttctata
    14281 ccccttatat tgacataatt tggataattt cgcacgcaat ttaagaataa aaaagaaagt
    14341 tgttagaaaa caactttctt agataactat ttttttggtt ctttgacccc ttttgcaaaa
    14401 atttggaatt tctcgccggt tttaggatca cgctgcaact tatcataatt gacaattaca
    14461 ccatcatcta agtctaattc aattcgtttt aatgctaagt gacccaactt ctcgtcatac
    14521 tcacgaactt cttttaattg cttctgaatc tttacaattt cttttgtcat tgcatttctt
    14581 tcttttgggt tatcacttgt tgaaatttgt tgctgacgca attcgattcg attgtcatac
    14641 gctttttgta gttcgtgtag gtattcagta cgtacttttc ctaattgatc tggtgtatag
    14701 cgatgcaagt acattaacgc tttaaagcca ttttgttttc ctgagtccaa ttgccaataa
    14761 attggtcgat tggagtatgt ttttaaatgg tctttgtaaa aatcttgtac gaagtaacga
    14821 cgaataattt ctcgacttgt ccctttgcca cctaaagtgt cagcgataaa ctggagattt
    14881 tcttcaaggg tttctttacc aaaagtaatc tcaacgaaat caatgaaacg attgacaatg
    14941 tcaatttggc tatccttgaa atactcatca tcggtgatga gtaaaacatt atcagtatca
    15001 ggtttaaatt tttgatagcg ggaaggatcc cattcgccgc cagcgaagat gagaccatct
    15061 tcgtctaggg agtaacgacc gaagatacaa cctattgaat aagaaataaa atccttaatt
    15121 tccctcgcct tatcaggtaa ccttgcagag atatattcat cttgaacctc ttttgttaat
    15181 tctttttcaa gagaataatg attaatgaat atgtcgttca gttcctcttc attcgatttt
    15241 agagtattaa attgattaac caactgccta cttagacagt taaatgcctc tgagagatct
    15301 tttttaaaca tataacttaa caaaatgttt cttctaaact cgtatgacgt ttcaagagca
    15361 ttatagtctt ttctagctat atcgatattt tcatccactt tttctcttat tttttttaat
    15421 tttctctcag atgtaacttt aagaaaaggt agttttccca ttggtccttc atggtaatcc
    15481 aaggtgggag aaataaaagt taaaaagtga ttaactaatt tagagtttac atagccaaat
    15541 atttcttcaa agtcagttat atcctttgag aacagaacag atcctttagt ttcaaaaatt
    15601 gcctgattct gcaatctaaa agatacttgt ccagatgaaa gtgtcgacca agtaattccc
    15661 tttttaaaat agtaattaag attttgtggt ctagatttta acttcccatt ttcattaaca
    15721 taatttttta tttcatctcc atcattctcc cagttaacca cgtattcatt gtttccatac
    15781 cattttctaa aacgaccacc tttagttgta ggaaaccatt tttttctaga ctttttagcg
    15841 tcctctaatg ttttagcatc aaactttatt ttgttaaatt ctacttcaaa ccaataccgc
    15901 aaaaatttat tgttatttcc ggttgccaac ccttgttttg catctgcaac atcgttagtt
    15961 aattttcctt gagcaaaatc agtgattacg ttatcgcttg cccagtaagc aatcggcatt
    16021 cctgggattt ttttgaagtt gtcttgatta gtactataaa aataatcgca ttcaccatgc
    16081 tgatgaattg cttctaacgt tttaattttt tgaacttcca ttccaccttt aaaatctgat
    16141 aattttatat agcttccatc ttgttcattt gaatttttta tcgtaaacgt acaaattgga
    16201 acggttgctt cttcaaaagc tgaatactcc atttgaatca aactagaaat gtttctttca
    16261 ttaattaaaa atgagcgtaa cttttcatag ctagaaatga acatccaaac aaatggcgtc
    16321 ataaaggaag catatccatt atcaatcagc atttggctat tcaatttaat aaacacagaa
    16381 aatagatctt ttttgacatc agaatagtta tcatttacat atttttttaa tttcttatcc
    16441 attttattaa gataaggcgg attagtgact accgctacat atttatcaac tagcatttca
    16501 gccacgtcaa gaatgtgcaa gtatttttct tgtatttcct tcatcccata aagaatatcc
    16561 atattcgtaa attcgttgaa ttttgatata tactctctta cttttcctaa gtattcttta
    16621 gttattgcct gattattttt atcgactaac ttaatgattg atccaagttc tttcccattt
    16681 tcaaattgat caaaaattaa ctctttgtat tcattccagc gttcactata cttatcattg
    16741 ttcaattcac taatacgctc ttgatactcg tctgtcactt taggagaatc aataaactct
    16801 cttaaattcg gcgatagact ttttttcaaa aaaagacgat cgtattgacg ccctttcatc
    16861 ataattgcaa aataagacaa ttgatacgct cttttatcga tttcaagacc atataaattg
    16921 tattcaacga ttgcacgtgc agcatcacgc tcagaatatc ctaacgtaag ataaatttcc
    16981 atcaatacat cgaaggcgta aactaaaata tgcccagacc ccattgcgtt atcgataatt
    17041 tttagttctt ctggttttaa attacttaca gatgttgctt gttcaaaagc atatttatct
    17101 ggaattaagt atttcaactt atttcttaat tcactattgg gataatgatc taaccaatac
    17161 tttcctaaac tattgtcaac catataacga acgacccaat ctgtggtaaa tagttgagtt
    17221 gctgccggaa tatcttgttt tttgacaatc cctttataaa tattcaccac ttgattatgt
    17281 ggctcactat tatagtactg atacaaccac ccaataatct ctacctgtcc accagcttga
    17341 acatagaaat catcctctgg aatacttaaa agatcagcga ttacaccatc ttttttaata
    17401 taagaagctg taaacaaaag ttctgtataa tcttctactt cttcaaatag ctcaggtaag
    17461 taatcattca attgattaca gatttttata aaaatcaatt gatacagctt gtccattgct
    17521 tctgctgaat tatctgtttt ccaagttctg acttgttgct gttcattact agataattct
    17581 tcaaagatat cggcatcata aatatctgta ataatatctg gctcaatttt cccacttatt
    17641 tcactagata atacacgata cgtgtcaggt aaataatcat ttacctccat aaaccgaatg
    17701 gcaatcaatc ggttaaacca cgtataagca acctcttcga ttaactcttg aaaagcttct
    17761 gaataagaag tgacagaagc acgttgtttt agttctgcaa tcaatttgtt tctttgcgct
    17821 atttcttttc cttgaattct tattcctgat ttttcgattt cttgtaaatt gctatcaatt
    17881 ttcttcacat cttcaatttt tgattcatca attcctaaac gttttgcttt agtcattact
    17941 tcatcaatta attttctacg ggcattgacc gcgaaattct ttatcgcttt cttatccatt
    18001 tttctttccc ttctatatgt aacctttgaa aagacaggca cctttttatg cctgtctttt
    18061 cactagaatt gaatcgtgat ttctgtattt tcttgaagtt gttccttcag tttttgatta
    18121 atttcagctg ttaactcatc aatatctgct gctgacttaa tagttttaac atgaacgtta
    18181 agtgttctca ttggtactgt tttctgttga atagtaggtt ttactatcgc tatttcttca
    18241 gcttttgctg cagagtctat ttcatctttt tcagtttcac gaatcaagtt tgctgcttca
    18301 atttgtttac gtgcttgttc ttcttgacgt ctgcggtttt cttcattatc gaaacgttga
    18361 ttaaagatca aatactgttc tgctacgttt aatgataaga aaacaagatc atctatagta
    18421 ttcgcttgtt caatttttgc tttcagttct tgaaattctt ggtcaactat tggtacaaat
    18481 tgatccttaa aatcttttcc ttctaataat ttaaatgttg cttgtttttc ttccgttaat
    18541 ttatttaata tttcctgact ttccaactct aacagttgat tatattgttc aataaattct
    18601 tgaatcaact catttagttt catcatatct gaataaggat cagccttttt caaaatggtt
    18661 ttcatctcat gaatcaattg atcaatttct tggctagaag tttgacgccg acttttttcg
    18721 attaatctaa ttttatcttg tgcattctcc cagatttttt tctgagtact attttgcttg
    18781 tggaaatttt taattttatc atatgtttca gcccagtcga ataattcatc gcgatatttt
    18841 ttgattgtat aaaaaaagtc ttcaacatct gacgtttgaa caattacttc aagatatttt
    18901 tttatttgct catattcata agcactaggg taggtataag tgttttgtaa atcaaaataa
    18961 gagcgtaaat tgtctaattg accttttaaa tatttcttga aattttccat tgtatgttca
    19021 ttgttatttt catcaacaat attacgactt tgaaacagtt ctctaccgat ttcgtcaacc
    19081 aatttttttg cttttggcga aatcaccgcg cttggttcaa tttttatctt ttcactttct
    19141 cgtcgttttt gaataatcat tacaatacta tttggatcat ccatccgtga aatttgtaca
    19201 ttgttataaa gtaaatcaat tttaccagac atgaaaagtt tagcgatgca ccattccaca
    19261 tcaagttctg tgaatccata cggttgtttt gtttcaaaac gatcacgaat tgttttcatc
    19321 gtaatcgtta ggtgatttct cttttgatca ttgataaaat tgaaaatttc ctgaactgct
    19381 tgctcatttg atggatcttc aataatttca tttttgcttt ctttcactaa atataagata
    19441 tcttcttttt ctttaggcgc atcaatttgg tttaatttat ggtatacttc ttcagccatt
    19501 ttctgaagtg ctgattggaa ttttgcttta aagtcggagc ctgtcagttg aatttctgca
    19561 ccgttataga aaaattttgc agatttcaac agttcattta attgatcgtt gatacttgca
    19621 cttagttcct gtaattcacc agatttttcc gaacgaatcg cgtcaaagtt ctttactaca
    19681 ctcgaataag tcgttgttaa ataaagattc attctagcat acattgctat atcatcttta
    19741 aattctttat ctgatggcaa ttctacgaat aataagttac gggaactctt aagcgcaagt
    19801 tctgcctctt gacctgctaa atcagagtat ggtgaaataa aattaactgt catttcagca
    19861 tttccagctt gcttgtatgg acgttgatct aacacttgtg cataagtaaa cgtataccgg
    19921 tttttaaatt tatttccacc tgacatgcct aatttttcat aggcaaaact atttcggtct
    19981 agaacgccgt caaaaattcg tttagatagt tctacgatca aatcactatc tgtaatattt
    20041 tgatttttaa tctcacgagt aatttcctgt tcttcatcag tttggaaaat ataactatct
    20101 aagttcttcc gcacaaagtt ttccttaatt aaaaggtcca atgcttcttc tactcgtttt
    20161 ttagtttcca ggcggtcttc gttgatattt cttatcatca agctcgtaat attttcaaca
    20221 tttggtttga tggcttgatc aacatattta atcatgaata aaattcgtaa gacatttacg
    20281 ttaaagttat ctatatcagt tggtctttga atatgagaat tatttgtagc ttgtgtaatc
    20341 actcggctaa ttgctgtatc aatccaacgt tctaacgagt aataaaactg atctaaagaa
    20401 accaaactgg ttgtatcatt ttccttattt cgttcagcgg cttctttaaa cattgctagt
    20461 aatgaacgtt caccagacga taagtttgat ccttgatagc tgtgattacg aatctcggtt
    20521 agaatttgcc ccaataaatt gaattgatag ggaataaatg gataaacttc tgcgtaattt
    20581 tcagcatctt ggaagagctt taattcagga ctatcaacaa agagtaattt atttttcaat
    20641 tctgtttgaa cagtttcaaa ttgtaaggct aaagaatcat tggcaaactc ttttttcttc
    20701 aaaatacgtt ctttaattac ttcatcggca tttgctgaag ataaactcac agttgtggca
    20761 aaacgatcct tgatcttaga aaaatcatta tcagaattgt tatcaaagtt tgttacgtga
    20821 tcaatcgctt cctgacttgt cactaatacc caagccttac cttcacaaat tcgacccaaa
    20881 tcttccacaa cggtttgtaa ctgcaaagtc aactcacgat taccgccgat atattgtccg
    20941 acctcatcga ctagaaaggc aatatgatgg tctgcttctt tggaatcaag atagctttta
    21001 actagatttg caaagtcatc aatgcttatt aaataatttc ctgatgcttt ttctaaaaaa
    21061 ttatcaatag cggcttcact cataaaatcg attttaagtg ccgcttcttt gatatcatct
    21121 tggatccaat caaactcatg gcgctcttct tgccattttg ccccattaat ctcttcaaaa
    21181 gcagctttga atgcatcaaa cttttcttct ttaattaacc gacgttcaaa atctgctaga
    21241 tgtggaatcg tgcttaatcc ttgcatttcg ttaaatacct ttaaaaaaac attcacgatt
    21301 ccgtttttgt cttttttacc acctgcatca ctttttgaat caatattaaa cagaataaca
    21361 tctgtattta tttgtgagca ccgttccatc gttgccaaag tcagtggatc tttgattttc
    21421 ccatcttctt tgaagtaatc aatggctttc ttgtcattta tttctcgatt tgcgagcaag
    21481 taagaaataa tttttaagaa atgagattta cctgaaccaa agaacccctg aatccaaaca
    21541 cccattttat ctgttggtgt attgatactc cgttggtagg catcaaaaat tgttttaaag
    21601 tgtttttgta gttctttcgt aaccacgtat tcttctaatt cttgttgaac attttcatcc
    21661 tttgcttgac cgaccttaat aactccttga atatttcggt caattggttt tgcaaaaata
    21721 tctttaatta gcatttaatc tcctaccttc catcccaact aaattctaaa tgctcgataa
    21781 taattatcat ctttattggt attaagaatt gtcaaactta attcatcata ttcccctgga
    21841 tacatcatca caactggtac gcgatcaaat acctgatgca ttttatttaa aatagagtgc
    21901 gctctaatta atggatataa ttcgccaatt cctgtcagga acacaactga tttttctggt
    21961 gtatgggcat ccacatattc aaaaaataca ttttcttcct caggtaaatc cattttcaat
    22021 aaacgaccaa tgctttccac taatttttgt aaaccacgtc gttcttccat cttaatcgct
    22081 ttttcagtga aaccgcgttt ttctagatac tctaacataa tcacatagag attataaact
    22141 ttcacttcat aattatcacc aacagatgtt ccagatatat cattaatata atctcttaca
    22201 attaactcgt ctttcggatc gtagtcaaag atataatagc ctacttcatt acctaaacca
    22261 cgattcaata aaaaatcttc tttttgaatt acttcattca acttttccaa atgctcttga
    22321 atcgataatg acattataaa attcctccca gtgctagtac aatatcttta cgattcttgt
    22381 caactaacca ttgaatcaat cgtttatcta ataatatcgg agtcattcgt ccatattctt
    22441 tttcccctct gactaatcct gtttcaatta gattcgtttg ataagcggca ataagccgtt
    22501 taatcgtata atctttccat tttgaaatat cttctgaact tctccgcttc tctgtaaaaa
    22561 aagaacggta atcaactggt gttaattgca aatttccttt acgtagattt tcagcatata
    22621 cctcagtcat aaattcatta aaaagatcat caatcataag gatggaaatc aaattcacta
    22681 acttttgatt atctatattt aactgattga aaagttgcaa tccagcttca tccagttgac
    22741 taactctcct tttcacgttc tgatagattt ctttttgacg gttactgctc actgcaaaaa
    22801 aaatattttc atgttcattt ttctctttaa tttctatatc tgtatatcct tctagtcgta
    22861 attgaatata taacttgaac tctgaaaacc aaaagcgttt agaaactaga ccagcagaat
    22921 attttttatt caatagattg cctcctaatc atctataatt caataagtaa acaagtgttt
    22981 tttgctcatc gttagcattc attttttagt atctactata caatacatat ttattatag
//
LOCUS       DAIGSZ010000045        22957 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.045, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000045 DAIGSZ010000000
VERSION     DAIGSZ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22957
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.045"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..132)
                     /locus_tag="NOB31_001848"
     CDS             complement(<1..132)
                     /locus_tag="NOB31_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI0974052.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
     gene            542..841
                     /locus_tag="NOB31_001849"
     CDS             542..841
                     /locus_tag="NOB31_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0974053.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            914..2275
                     /locus_tag="NOB31_001850"
     CDS             914..2275
                     /locus_tag="NOB31_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCI0974054.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            2297..2557
                     /locus_tag="NOB31_001851"
     CDS             2297..2557
                     /locus_tag="NOB31_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974055.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2571..3323
                     /locus_tag="NOB31_001852"
     CDS             2571..3323
                     /locus_tag="NOB31_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HCI0974056.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(3417..4022)
                     /locus_tag="NOB31_001853"
     CDS             complement(3417..4022)
                     /locus_tag="NOB31_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0974057.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(4075..5049)
                     /locus_tag="NOB31_001854"
     CDS             complement(4075..5049)
                     /locus_tag="NOB31_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HCI0974058.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(5427..6146)
                     /locus_tag="NOB31_001855"
     CDS             complement(5427..6146)
                     /locus_tag="NOB31_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0974059.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(6273..7544)
                     /gene="celB"
                     /locus_tag="NOB31_001856"
     CDS             complement(6273..7544)
                     /gene="celB"
                     /locus_tag="NOB31_001856"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCI0974060.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7697..9094
                     /locus_tag="NOB31_001857"
     CDS             7697..9094
                     /locus_tag="NOB31_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0974061.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            9175..9615
                     /locus_tag="NOB31_001858"
     CDS             9175..9615
                     /locus_tag="NOB31_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI0974062.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9763..10089
                     /locus_tag="NOB31_001859"
     CDS             9763..10089
                     /locus_tag="NOB31_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0974063.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            10090..10839
                     /locus_tag="NOB31_001860"
     CDS             10090..10839
                     /locus_tag="NOB31_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974064.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10919..11374)
                     /locus_tag="NOB31_001861"
     CDS             complement(10919..11374)
                     /locus_tag="NOB31_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCI0974065.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11801..12076)
                     /locus_tag="NOB31_001862"
     CDS             complement(11801..12076)
                     /locus_tag="NOB31_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974066.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            12370..13185
                     /gene="thiD"
                     /locus_tag="NOB31_001863"
     CDS             12370..13185
                     /gene="thiD"
                     /locus_tag="NOB31_001863"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HCI0974067.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(13514..14965)
                     /gene="cls"
                     /locus_tag="NOB31_001864"
     CDS             complement(13514..14965)
                     /gene="cls"
                     /locus_tag="NOB31_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCI0974068.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            15306..17972
                     /locus_tag="NOB31_001865"
     CDS             15306..17972
                     /locus_tag="NOB31_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI0974069.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            18336..19088
                     /locus_tag="NOB31_001866"
     CDS             18336..19088
                     /locus_tag="NOB31_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCI0974070.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(19110..20264)
                     /locus_tag="NOB31_001867"
     CDS             complement(19110..20264)
                     /locus_tag="NOB31_001867"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HCI0974071.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            20449..22890
                     /locus_tag="NOB31_001868"
     CDS             20449..22890
                     /locus_tag="NOB31_001868"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HCI0974072.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         7392 a         4028 c         4772 g         6765 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaaatgata ttttacgagg aggaagaaaa
      541 aatgaaaaat cggttaattg tcgcatgtgg aagtggagta gcaacgagtc agacaatcgc
      601 tagtaagatc caaagtatgt tagaagatga cggcatcgca tttcctgtag aagcagttga
      661 ttacaaatcg attcaaaatg agcttctaac tgctggaatc tatgtgtatg tcgcacaacc
      721 tgatgaggaa gtacttgaac aagcaaaaga tttgggtatt gaagtatttc caggaattcc
      781 atttttaact ggaatgggtg tagaacctat ttatgacagt atcaaagagt tagtacagta
      841 aaggaggatt gttggataaa aaagttggtt catagtttta tttactatat ttagaaagaa
      901 agaaggttta tttatggaag ttttccaaac cattatcaat tatgttttga acttaggatc
      961 agccattttt gttcccctga ttattttgat acttggattg ttggcaggga tgaaattaaa
     1021 aaaagcattc atgtctgctt tgactttagg gattgctttt agcggaatgt ctatggtcat
     1081 tggctatatg tctaacgcag taagtccagc atcagaagca ttggctaaaa atacgggaat
     1141 cagtttgcct gcacttgatc ttgggtggac aggtgcagca agcatcacat ggtcgtggag
     1201 ttatgctttt atattttttg cagtaacgat tggggtcaat tttgtactgt tactttttaa
     1261 ttggacgaag acgttaaatg ttgatatgtg gaatgtttgg gggaaagctt taactgctta
     1321 tttagtttat tatgtttccg gtagtttggc tgcaggcttt cttactgcaa tggtccaagt
     1381 tatattggaa ttaaagcttg gtgatatgtt tcaaaaacat atacaagatc tcacagggat
     1441 tccattagta acagtgactc attttatgac atctgccgct gtcttgttgc tgcctttcaa
     1501 tatgatcatg gataaaattc ctgctttaaa taaacgagcg gatacgaatg cattgaagaa
     1561 gaaaattggg atcttctctg aaaactctgt aatgggattc attattggat tggggcttgg
     1621 ctttgctgct gcgtatggcg tttcaggttc tcttaatcta gcgatccaaa cagctacagc
     1681 attaagtttg tttcctatga tctctaaaat gttcatgcaa tctttgtctc ctctagcaga
     1741 cgctatgtca gaatttatga aaaagcggtt taaggatcgt gaagtatata tcggattgga
     1801 ctggccgata ttagctggtc gttcagaaat ttgggttact gctattttac ttgttcctgt
     1861 gtttattggt tatgccatta ttttgccagg aaaccaagta ttgccattag cagggattat
     1921 caactattcg attgcggtcg gcggattact tttaacagga ggaaacttgg ctcgtatgct
     1981 gatcttggga atcatcacta tgcctattta tttgtacggg gccacttacc ttgcgccaat
     2041 actcagtgat ttagcagaaa aaagcggagc agtcgaggga atcaagaaag gacagttgat
     2101 cacatggtca tccatagaag ggccggagtt cagggtttta tttgcggagg catttaatag
     2161 gaatattctc gctattgtag gatgcgtgat ttttctagga ctgtttgttc tactttataa
     2221 atatatgata aaagcgaaag taccgagtga acgttatgct gaactacaaa aatagcattg
     2281 aaatggtggg aaagtaatga aaagagaaga gacagataaa ataaaatgga cagtcgctct
     2341 ttgtggtaca cttctgctat ttctatatgg actctttact cagaatatca tcatcaatct
     2401 attggtcatt tttttcgcac tagtgatcta taaatatgga aatcacgttt tattcagaga
     2461 gtacgatgaa aaaagaaaac ggaaaataga agaatcaatg aaaataaaag aagctaccaa
     2521 agaaatattg agagaaaaaa gttttataaa aagataatgg aggggtcatt atgtcagatg
     2581 gacgtatgtt atttgagaga gaacgacagg acatggcacg tatcgtaaga gtgattttcg
     2641 aaaggaaaaa cacaaatgtc gcaggaggga atttttcctt taaaaccact gatgatcaag
     2701 ggaaagacta catcatcatg acgccgacca tgatgtcaga agcctatcta ggagagattt
     2761 ctcctgcaca ggttctagta gtagaaccaa gaacgcgtag aatcgttgac ggagtcggtc
     2821 atttaactcg tgaaatcaat atgcatgaag cgatgtatga gactaatcca gctatcaaag
     2881 ctgtcctaca tgctcatgcg cctaatgcaa tgttctgggc gactactggg ttgcctatgc
     2941 ctaatttgac agaagccaca gctaaagtaa aagagattcc tgtcatggac tttgagccta
     3001 attgctctga agaacttgct gaattgacaa gcgactatgt aaaaaaacag catctcgaat
     3061 taccgcatat gttgctgctc aactctcatg gcgtattgat caacacaggt ggagaatcag
     3121 gaatcgaagc tatccataaa gcactgcaaa tccttgatac agttgaatgg aatgcagaaa
     3181 ttgcctacaa gcagacgatt tttcaagcat tagggattac tgacggtttt tattcaaaag
     3241 gtgagaaaat cgggggattg gaagagttga aacataaaac ggctatttat aataaatctg
     3301 ttattgcagc tggtggagac taacctatct gacacaaaaa actacgactt tcacaaaatc
     3361 tgatccagat cgatatctgc ttcaggttgt attatgtaag tcgtagttct tttcttttat
     3421 ttagttaaga ggtggtctgt ccattccctc gcttgcttga tttcgtccat cgtcaactga
     3481 tgacctgtta cagttagctg aatagtcaca tttgcttggc gtgtttcgaa ttgatcggcc
     3541 aattctttaa aggaagcagg ggaaacgatt ggatcgttat caccataaga aatccagacg
     3601 gttttatcct ctaatgtgga acggctttga tgaacaccta gagacatcgg atggaaaaac
     3661 aaccctttat ttagctcggt ctcacgctcc aataataaat gagcagcgat gtttgcgcca
     3721 tttgaatagc cgacaagcag ccagtcactt aacggtatca gttctttttc gctgatttct
     3781 ttgatttttt catggagttt atctgtttct ttttccaaac tgtccaggtc gaattgattc
     3841 aatccattac gcttgaaaaa acgattcatc ccatcttctt ggaccgtgcc acgaaaagaa
     3901 agcaatgtac tgtttggtgc aagaaagtga gcgatatcca gtaaagaatg ttcatcgcca
     3961 cctgtgccat gaagtaagat caaatgcttg ccacttgttc ctttttcaaa aatgtaggtc
     4021 attttgttcc ctcttttctg tttctataga tgcaaatgaa gtagcatgaa gagattattc
     4081 acgtttttta tttgcatcac ttgtatcgaa aggacggaca taagcttcaa tggcttcacg
     4141 acgttcttct aagaatggag gaagagatag tttttctcct gctgattctg ctggttcatc
     4201 ttcaaggaat ccaggaccat cagttgctaa ttcaaacagt acgtgatgag cggctaggaa
     4261 gtactcagat tggaaataga aacgatcgac gaaaccagaa tttggcaatt caatcttatt
     4321 gattacttga atccagtatt ccaatgcttc tttgtctgct acacgcaatg ctaagtgatg
     4381 gatatttcca aatccttcga ttgcttttgg caagtctgtc cgatgttcaa taatgatgct
     4441 tgcaccattt cccccttcac cgatttcaaa taagtagaaa tctcctgaat ggtctgtttc
     4501 tttgaatcct aagatttttt caagaatcaa gcggatatgc tctaattgac tgacacggac
     4561 aaagacaggt ccaagtcctg tgatcgcaaa ctctgtcggt acattgctgt ttttccaagg
     4621 aatgccagct gctacacctt gattgttttc gtcagagatc aattgataat actgattatc
     4681 gaaatcttca aattcgatat attttttgcc gaaacgttca ttgattgctg aatgagtaac
     4741 gtcatatttt tcaaaacgtt ccaaccaaaa gtctaatgct gcgtcacttg gcacacggaa
     4801 agaagcacga gagatcgtat ctgttccttt ttttcctttt ggctgatttg gaaaatcaaa
     4861 gaaagtcata tctgttcctg gcgcaccagt atcgtctgta aagtaaagat ggtaagtttc
     4921 gatgtcatct tggttaactg tttttttgat taagcgcatt cctaaaatat ctgtaaaaaa
     4981 gcggtagatt tttgtagcgc tagatgtcat tgctgtgacg tggtgaattc ctctgatttg
     5041 tgtatccatg ataaatttcc tcctgttaac ttacaaaaag taagtagttg atttagacat
     5101 agtatagagg gtgcatctct attttgcaat taatttgtct tctaaagtat caggaaggaa
     5161 tcaagaatgg aaaagaggag ggacggatca ataaaataaa aagacttacg actagctgta
     5221 tcgatttcaa aaaaactagc tttaaaaagc taactttaga atcattacgg gtggtcataa
     5281 gtctttttat gctgagttat tttttcattt ttgagctaat gcttaggata gaatagaatg
     5341 ttgatttcac gatctcttct tgttacttga aactgcttac cactgtcacg atctcttggt
     5401 aaacggcttt ttcacaacct ctttggttaa gttgaacgca catccagcac agaatagttc
     5461 cgaacatcaa atcggtttcg gctggaagaa tattcaatcg gctgtccatc tttgagatag
     5521 acgacttgct gaacttccag tacaggatcg ttttctgcac agttcaaata ttgctgatca
     5581 tattcatcac ttttatctgc agaaatagca cgataagccc ctgcaaaatg gacattcaat
     5641 tcttgatgaa gatgatcata gatagaggct aacaaatgtt ctttttttaa acccggcaca
     5701 agatggactg gcataaaggt atgctctaaa acatatggct cgccatctaa gatccttaac
     5761 cggtgaatat tgtagacagg ttgctcggca tcgatcatca atcgttcttg gatatattga
     5821 ttagggaatt caacatcaaa atgaatgatt tgactcttca aagaacgatg tctgcgtttc
     5881 atttggagac tcaaaccttc atactcgtta gcgggcgatg tgtctttttg cataaatgga
     5941 tgattcaaga ttttcgttcc tgatcctcgc tgcgaataga caagtccttc cattgctaag
     6001 atattgatgg cttttttgat tgtcatccgg ctcgcaccaa attcttttac caagtcgact
     6061 tgattaggca aaaaactatc gagaggatac tcttttgaac ggatacgttc tcttaaaata
     6121 tttgcgattt cttcgtattt tggcacgtta ttcacctctt ctagagtata acgaaagatt
     6181 atgcttccga caactcgaag tagcatctgg aacattgttt attcgaaaaa agaggtcatg
     6241 acaagttttt gtcacaaccc cttaatgatc tattaagcaa tatctaaatc tggttgttta
     6301 tctagtactt tcaggaatgg gtaccagata aaggcaacga tgacaaagtc gatgacttgc
     6361 agcataccac caagccatga atttgttgct aagacaccgc ttgcaatgat tggcacagtc
     6421 catggaacag agacgccagt tggtgcaggg acaagtccag cagccattac caaataattg
     6481 aacgtcgtta cgattagagg tgccacaacc caaggaataa ggattgttgc attcaatacg
     6541 atcggtagac cgaagatcgc tggttcattt acattgaaaa taccaggtgc taaagctaat
     6601 cgtccaacat cacgatactg tttcttttta agaacaaagg ccatcaataa aacgacagct
     6661 aaagtcattc cagagccacc aataccaaca gtgaaggttt ccatgaatgg ttttgtgatg
     6721 atgtgtggta attcttttcc atgttgataa gcttctaagt tatcaagcat cagtgtattc
     6781 caaatcgggt ccattacaga gttgacgatg atttgtccgt gaagtccgaa gaaccataag
     6841 aattggacaa agaacaaagc aatcaatgtt gcaggtaaac tacttcccaa accagttaat
     6901 ggtttttgga tcacttcata aacgacgtca tgtaagttag cattgaaaat accagtcatc
     6961 acagcattga ttactaagaa aatagttagt gtcactacag cagggatcaa agcggcaaat
     7021 gattttgtta ctgcaggcgg aactccatca ggcattttga tctgccagcc gcgtttcgtg
     7081 attctgcagt agatttctcc agccaagaaa gcagcgatca ttccaatgaa cattcctttt
     7141 gcgccaagac gatcaagtga aagcacacca gtcacatctt caccgccagc ggttttcatt
     7201 gcaaaaggcg taagaatcaa gaagctggca aaagacacgg caccaccgaa aataccttca
     7261 acgtcataag attttgataa ataatagccg ataccaaaag taacaaaaac cgacatgatg
     7321 ctcattgttg cattttgccc attaccgaat aaattcgata aagttccctt tgttgcgtca
     7381 ctgaaaaaag gcaagttatt gataacgaca acgatcgaac cgaacatcgt taaagggaag
     7441 gaaagcatga aagcatcccg cagcactgta aggtaacgat tttgccctaa taaattagct
     7501 aagggcatga ttttctcaga aagcttgtcc ataaaaccgt tcatttttat tcacctcaaa
     7561 tttatttgca atcgattaca tacaaagtat aacgccaaaa attttaaatg tctagtcatt
     7621 ttcataaaaa gtattgattt attttttagg gttcgttatg attacggtat caagaaaaaa
     7681 gagaggaagt aaaaaaatga aaacctacac attcccagaa aatttttggt ggggttctgc
     7741 tgctagcgga ccgcaaacag aaggaagagt aagtgatgat ggtaaaggag aaaatatttg
     7801 ggatcattgg tatgaattag agcctgaaaa attcttcgat caagtaggac ctgaaaaaac
     7861 ttcgcaagtt tacacaaaat acaaagaaga tgttcagtta atgaaagaaa ctggccataa
     7921 cacatttcgt acatctatcc aatggagtca tttgattcca gaagggacag gtgaaatcaa
     7981 tcaaaaagct gtttcttttt atcgagatta ttttactgaa ttgctggata atggtattga
     8041 accttttgtg aacctttacc atttcgatat gccactacca ctgcaagaaa aaggcggatg
     8101 gttatcaaga gaaacggtcg acgcttatgt ttcttatgca gcagcgtgct ttgaactgtt
     8161 tggagatctg gtcaaaaaat ggtttactca taatgaacca atcgtacctg tagaaggagg
     8221 ctacttgtat caattccact atccaaatca tatcaatatg aaagaagcgg tccaagtagg
     8281 ctatcatgag aatctagcaa gcgcaaaggt aatcaaagcc taccatgaag gcggacatga
     8341 tggtgagatc ggaatcatct tgaatctgac accaagctat ccgagagatg aaacgaaccc
     8401 agaagatgta aaagcggcga agatcgctga cgcattcttc aaccgatcat tccttgaccc
     8461 tgcagtgaaa ggagagtttc cacaagagtt gatcgaaatt gtcaaagaat tggctataat
     8521 gccagagatc catgaaggag acctagaact catccgtgaa aacacgattg acctgctagg
     8581 aatcaattac tatcagcctc gtcgaatcaa agcaaaagaa actccaatca atcacgaaca
     8641 tagccccatg ccagatgatt attttgataa ttacgacatg cccaataaaa aaatgaatcc
     8701 atatcgtgga tgggaaattt acgaaaaagg aatctatgat attttaacga atacaagaga
     8761 aaactatggt aatatcaaat gctatatttc tgaaaatggg atgggggtcg aaggagaaga
     8821 acgatttgtt aacagcgaag gaattattga agatgattac cggatcgagt ttgttacgga
     8881 tcatttgaaa tacgtccatc aagcaatcca agaaggaacc aattgtgtgg gttaccacat
     8941 gtggacatgt atggacaact ggtcttggac aaatgcttat aagaatcgct atggctttat
     9001 cgctgttgat ttggcacaag acggtaaacg gacgatcaaa aaatcaggtc gctggtttaa
     9061 aacggtctct gaaaaaaacg gatttgatgc ctgatatttt ttgataaaac gttcacaaaa
     9121 tgtttgttct aacactgtaa tcgtgctaca ctaacagtga aggaggcgtt tacaatggta
     9181 gatacttatc gtaatatttt agtagcaatt gatggttctg aaaaggcaga aaaagcattt
     9241 cttgaggcaa tcacgattgc caaacgaaat caggcaacgt tgcacatcct gtatgtcaat
     9301 gaagtaacag gcaattactt tggtgatttt gcatttgtta caacaagcct tcaggaagaa
     9361 ttggatgagg ttgcggaaaa ccagatgaaa gaacatcgaa acttggcaat tgaaaaaggc
     9421 ctgacagata tcgagacata tgttctttac ggttatccaa agacactgat tgctaatttc
     9481 catgaatcga aagaaccaat cgatctgatt gtcatggggg cgacaggtct gaatgcggta
     9541 gaacgtgcac tagtaggttc cactacttcc tatgtagtca accacgcatc atgtaacgtc
     9601 atggttgtaa aataaataaa ttaagggaac agaaagcaaa aaagcataac gcttcttttg
     9661 ctttctgttc cttttatttt tttgtaaaaa attactttac ctgatgaagt aatcatgcta
     9721 ttctaattac aacgacagat ggagtaatat ggaggaaaga aaatgatttc aagtgatgga
     9781 atacgcggat acaatgatgc gattatttta tcgatcctta acaaaaacga ttcttatgga
     9841 tatgaaattt ctaaaacgat tcgtgagagg acaaatgatt cctatgtgat caaagagaca
     9901 acactttact ccgtttttgc ccgtttagaa aagaatcaac tgattgtttc gtatcctgga
     9961 gaagtgactc atggaaaaaa gcggacatat tataaaatca ctgaaatagg gcgtaatctt
    10021 ttagaagaaa aaaagcaaga gtggctgacg acgaaagacg tagtcgatca atttttggag
    10081 ggaaattaaa tggatacaat ccgtaattat ttagacagtc tttttatcgg agtacctcaa
    10141 agtaccgaga tagataagct gaaaactgat ttgttggcaa atatggaaga ccattatcat
    10201 gaattgatgg gagaaggaaa aaatgaacag gaggccatcg gtacagtaat ttcgacattt
    10261 ggttcaatcg atgaattatt agaagaacta gatgtcgaaa aaaaacatca agctgacgag
    10321 acggaaacaa acacagcttc tatttattta agcgaagcag aaaactactg gaaagaatac
    10381 agagcggcaa gtctccaagt ggcatcaggt gttctattca ttagcttatc ttttgcaagt
    10441 tttcttttct tttgttcagc aggatatgtg ttcatgggta tttcttgtct gattttcggt
    10501 atagcattag ctgtcggttt ttttattgct tctggtatga aaatcacacg tttaaatcac
    10561 tttttgcacc atcggaaaat acctgaaaaa gtattagcag aagcaaaaga aaaagaagaa
    10621 gagtatcagc gaagttttgg cttctcactg attgcaggaa ttggattatg tattttttca
    10681 cttttcccac ttttggcttc tttaatgtgg tatatggatg gtagtatcgg tgcctctata
    10741 ttttttgtta cggtaggaac gggtgtcttc ttgatcattt atggcagtct agtccgtcat
    10801 tcttatcgtc aattcactca aagcgcttat tactggtgaa tgtattcaga tttgtaaaaa
    10861 tattctattt atccggcgta gaaaaaaaga ctgtgacacg cttttgtcac agtctttttt
    10921 atatataata atttaaaaat tcatcatcta aatccgtaga attttctaga ttgcttaccc
    10981 atgtaaaatc gttatagaca gatttcagtt gacttctgcg ccattgtaca gggataaaaa
    11041 gacgcatgct atcttcattg aatccgacta ataatttctt tccgtcagta atgatgggac
    11101 gttgtaacaa agtaaaatgc gagacgatca gatcgacaag ctctgaggtc gtacattggt
    11161 cgatttggtc tttcaaattt ttataatcaa tcgagcgttt agctaataga tcgtcaaatc
    11221 cgttttctgt taatgacaat aaataaaata tctctttcct tgttaaaggc tgtttaggtg
    11281 tgaaaattcg ttctctgtaa ggcatttgat ggtctttcag ccagtttgcc atcagatggt
    11341 aactatgtgt gcgagaagaa tagatcgtaa gcataaaaaa actccttaaa tagtccatta
    11401 atttgttaga tctgttgaga taaataatag gtaaggagct gtgcataagc attgatcaaa
    11461 acaacccaaa catcattaga aataactttc taaagtctta aacttgcgac gagaagcaac
    11521 tagactaata gaaaaaatgt cttagccatt tggcttcctg tttgtttttt tgcttatgct
    11581 gcagctcctc gggaaagggt tctaacaatt tgaagaaggt tgatgattga tctagtttaa
    11641 attgtgtgaa atttgaaatc tggtgttttt actagatgaa tcacctaaca actatgatta
    11701 taacttatag aacttctgtt ttgcattcgg ttttgttata gttgttataa agttttattt
    11761 tattacagaa catttttaat taataaagaa cagttagaag ttaaaattgc tgattcacat
    11821 agagtttatg acttcttgga aattcttttt caatcagttt tttcatctgt ttatgaaatt
    11881 cttttttttc agtaaacata aaggtttggg tatcgtaacc ttcttcatgt aggaaataga
    11941 ttattccttt ttctgtgttt tgcgtataag cttttatact cctgtctttt ttgaaagaac
    12001 agatcgtata gccatctatt tggtctggta gtcgtttgat tttcttcaaa atgacttttt
    12061 tatcctcaag tttcattttt ttcacctgac tttatttttt tcatatggaa atcatagcgc
    12121 ctttggttat atgaaaacaa gaaggatact gaaatatata taaatcaaat agtggttatt
    12181 tattattaga atagcgaata caaataaacg accactattt tctgatttat tgcaaatgtt
    12241 ttttcaaata aatttgatta ccaagaaaag gtagtggtat atttactgag ggatactttg
    12301 aaaaacatat gatagaaaca gtaacagtat tatgaaaaat ctttttataa aaatggagga
    12361 atcgatttga tggaagatca gtatgtacaa gcaatgacga tcgcaggatc agatagcgat
    12421 ggaagcgcag ggatgcaagc agatatgcat acattcttta caagaaatgt ttacggtgtt
    12481 tctgtcatga ccgcatgtgt tgcaggtaat tcttacggaa tcggagcaag tgtgacattg
    12541 ccaacagatt ttatcgacaa agaatttgaa ctgattgcga aggactttca aatacgtgca
    12601 gctaaaacag gtatgctagc agattcaaag ttgattgaga cagttgtaaa aaattaccaa
    12661 aaatatgatt ttggaccatt agtcgtggat cccgtaatcg taacgaaaca tggaaatctt
    12721 ttactagaag aatctgcttt gcaaagcttg aaagaaaagc ttgtcccttt ggccgaagta
    12781 ctgacaccta atttttatga agcagaaaag ctgactggac ggacattagc agctgaagaa
    12841 gattttgtgc aagcagcaaa agaactgcaa gatatgggtg caaaaaacgt tatgatcaaa
    12901 ggacatcatg ctaaaaatgc gcagcaagaa acagtcaatg actacgtatt gttcgaatca
    12961 ggaaaatcat tttggttaaa tgcaccattt tatcctaccg accggatcaa cggaactggc
    13021 gattcgctat ctgcatgtat tgcagctgag ttagcgaaag gaaaaacagt tgaacaagcg
    13081 atccgattgg caaaagacta tgtaaaccgt gcaattcgtg aagaaataaa tgtagggcac
    13141 aaatatggcc ccatcaatca ttgggcagct ggtgaattag agtaaaagaa agaagttgtg
    13201 aaaaagttgc cctgcatcaa gtaataagaa cagccaagta aaaacagctt cttatgtttt
    13261 taacttggtt ggacttatta ccgcagatgc aagcttttga acaccgttta agaaagaggt
    13321 cgtgagcctg ccgtccagct ccgagtcaca aggaacaagt tcaaaaaaca gcttctcatg
    13381 tttgttgaat attgtgactt gtgaccgagg agttggcagg agaacaccgt ttgttcggaa
    13441 gaagggactg tgacaagatt tttgtcacag tccctttaat cttagtatat ttttctctac
    13501 ttgaataaaa aaattatagg attggagaaa ataatcgaga aatttgttgc ttgaataata
    13561 gccagttaga catttccttg actgtttcag ttgtcatgga tgaacaatgt gtctcatctt
    13621 ctttgaactg agtagcaagt tcttctaaaa actcaggatc gtaaatgaca gcacttgttt
    13681 caaaattcaa tcggtagcta cgaatatctt gatttgctga acctaccatg cagatttcat
    13741 catccattat caatgttttt gcatggagga agccgttctc atagacaagg atttgtacat
    13801 tttccttgat cagctgccga gcataatatt gtgttgctcg ataaataaaa ggatgatccg
    13861 gtttgttggg aatcatgatt ttcacatcta caccagaggc agttgcgatt tttaaagcag
    13921 caatgacact ttcatcagga acaaggtaag gtgtctgtat ccaaacacgt tttttagcag
    13981 aagtaatcaa tttgataaat gaaagcttga tttgttccct ttcgttattc ggtccgcttg
    14041 aaacaagctg gatggatgta tcagcaagct tagattcatc tcgatctgct tttttaaaga
    14101 aataattcaa atgatagccg accttttttt cttcaggtac cgagacgttc cagtctgtta
    14161 agaagcgaag ctggagcaaa gaagaagcgg caccgaaaat ccgtatatgc gtatcgcgcc
    14221 aatagccgaa tttttttgtt gtatttacat attgattggc aatattgaaa ccaccggtat
    14281 aactaatctt tccatcgatc acaacgattt ttcggtgatc atggtaattc aatcggaaac
    14341 gaagtaatgc cctttgtgag gtaacaaatg tatggacatg tccaccattt ttgattagac
    14401 gattgaaatc ttttgctttt gtgccatgag agccaaatgc atcatataat attcgaactt
    14461 ccacgccttc tgcggctttt tcttctaaaa catgtaagac ttgctggccg atattatctg
    14521 tcacaaatgc gtaatattcg atatggatcg aatgtttggc tttttttaga tcttgaagca
    14581 gtgaatccaa tttctcttgt ccgtctgtga gaagagtgac agaattcatt cttgtcagcg
    14641 gcatacgatt taatgaagag aagaagtcaa caaattgctg tttgtcttta tcgcccatgt
    14701 caggatcgta atgttcaatg gtatctcctc taaaagactg aaagttttct aattctttca
    14761 agtcactttg tcggagatag aattttttct tatccgttaa tccacgtccg aaaaataaat
    14821 ataatacaaa gcccacccca ggaagggcaa acaatactaa gagccatgcc caaatggctg
    14881 ctacatctcg gggtttgatc aaaatagcca ccaaagcaat aagtgcattt aatagataaa
    14941 gggcggttat aatactagat accacaaaaa tgttcctcct tacatacaat aacattagta
    15001 tagcatgata gaagaaagaa gcctaccaag gtgaatatac ttttcactcc tttcatgaaa
    15061 atgtaggtaa atcgggctaa agtagttgct ttttgtaggt taataaggta ggatattagt
    15121 acagttgaat atctccttag gggagtaacc ggcaacgttt gttgcgataa tatcaacagt
    15181 aagttaacca aatggttttc tggtattgta tgaaatggtg agacctaaga caaatgcgta
    15241 tttgtcttag gtctcttttt tttcagacag gactagggcc aagatcaaaa aatgggggat
    15301 gaaatttgga aaacaaggaa caagcacaac aagcggtcta taaagaaacg atcgactcgt
    15361 tgatgcagca aacgcagagc tcaaccgatg gattgagcac cacgcaagcg aaggaaaaat
    15421 tagaaagaga tggcttgaac cagctaaaag aaaagccgaa gaagccaact tggaaattgt
    15481 tcttagaaac tttcaaagat gcaatggtta tcgtattgct gattgtcgca ctgattcaga
    15541 tggtcatggg tgactacatc gaattcttag ttatttttgc agtattgatg ttgaattcta
    15601 taatcagtgt tgtccaaaca aaaaaagcag aaggttcttt agaagcgttg aaaaaccttt
    15661 cagcgcccga tgctcgagtg attcgtgatg gtaaggaaaa aacgattccg gcaaacgaac
    15721 ttgtggtagg agatatcgtg ttgttagacg caggcgatta tgtacctgct gatggacgtt
    15781 tactagatgc gggatcatta aaagtagatg aaggtatgct gacaggagag tcgacttctg
    15841 cagaaaaaga agtaacggat atcacaagta cggtaccaat cggagatcgt acaaatatgg
    15901 tattcagtgg aacgatcgta acttacggac gcggtaaatt cttagtgact tcaactggga
    15961 ataatacgga gatcggacaa gttgctggcc ttttggaatc aacaactgag caagtcactc
    16021 cgttacaacg aggtctggat aaattcagta aaaaactaag tttggctatt ttggcattgt
    16081 ctttattgat tttaggtatc caactgtttc gtatttatct tggagaaggt acaggagata
    16141 tgactgcaga tatcgtcagc gcagtgatgt ttgccgtagc cgtagccgta gctgctattc
    16201 cagaagcatt acagtctatc gtaacaatcg tgttatcttt gggaacgaat aaaatggcaa
    16261 aacgtcatgc cattattcgg aagcttccag cagttgaaac acttggttcg acaagtatca
    16321 tctgtacaga taagactggt acattgacac aaaacaaaat gacagttgtt gactactttt
    16381 taggtaatgg cgatactggg gatttcacaa atgacccttc aaaatggaca gctgacgaac
    16441 gtcgcttgat cgaaatcagt gttttagcga atgatgcatc gatcagtgaa gacggtacta
    16501 aattgggcga ccctacggaa gtagcgttta tcgactttag tgaaaaatta aaccagcctt
    16561 atcaggaaat ccgaaacaac tacccaagac aagcagaact tccttttgac tcagatcgaa
    16621 aattaatgtc tactggacac acaattgata acaaaaatta cttgtttgtt aaaggcggac
    16681 cagatatcgt cttccaacgc agtaaaaaag tattgctaaa tggtgaagtc gttccgatga
    16741 cggatgaatt gatgaaaaaa ttccaagagc aaaatgaagc tttttcaaca cgcgcattac
    16801 gtgtactagc ttttgcttac cgtccacttg ataattttga tttatcattt gaagatgaag
    16861 acgatttgat ccttgttggt ttgcttgcta tgatcgatcc tccacgtgct gaagtgactc
    16921 aggcggtaac agaagcaaga agtgcaggaa tcaaaacaat catgattact ggtgaccaca
    16981 aaacaacagc tgttgctatc gcaaaacaaa tcgggatttt tgaagaagga aacctggctt
    17041 tgaccgggac ggaactagat gaattgacag aagatcaact aaacgaagtt ttagaaaaag
    17101 tcactgttta tgcacgtgtt tcacctgaga ataaaattcg tatcgttcgt gcttggcaaa
    17161 ataaaggtca tatctcagct atgacaggtg atggtgtaaa tgacgcacca gcattgaaac
    17221 aagcagacat cggaattgct atgggaacgg gtacagatgt ggcaaaagat gcagcagcga
    17281 tggtattgac ggatgataac tttgcttcta ttgtcagcgc agtagaagta ggacgtaatg
    17341 tgtttgataa tatcaagaaa gctatttctt atctatttgc aggaaattta ggtgcgatca
    17401 ttgcgatcat ctttgcctta gttgctgact ggtccaatcc atttacagca ttacaactgt
    17461 tgttcatcaa tttagtcaat gattcactgc cagcaattgc attaggtaca gaaaaagctg
    17521 aacctgctac gatgaaccgc ccgccaagag atccaaattc aggaatcttt acggacaaaa
    17581 cattgatttc tgtaacgtat cgtggtgtgc tgattgggat tgctgttatc tttgctcaat
    17641 ggcttggcat gcagcattca cctgaattcg gtgtagccat gtcattttca acattgattt
    17701 ggtgtcggac attgcaaaca ttcccagcac gttcaaacac acaaacagct atccaagcag
    17761 ggttcttctc taacagaagt gtcttactag ctgtagttgt atgtagcgcg ctttactgct
    17821 taacaatgat cccaggactg aaagaagtct tctctatccc atcagcattt ggattgacag
    17881 aagtctttac atgtatggga atcgcacttg tgacaattgt tttgatggaa atcactaaat
    17941 tgatcattgt acgagtacaa ggaaataaat aaaacgaatc aacgaggttg tgagcctgcc
    18001 gtttaattct gagtcacaag gtgcaatttc aacaaacagc ttctcatgtt tgttgaatat
    18061 tgtgacttgt gaccgaagag ttggcaggag aacaccgttt aaggaagaag ttgtaaaatc
    18121 agcattttga gctaatactg agggtcatct gattggacac tgtttattcg gaaagaggga
    18181 ctttgacacg actttggtca cagtcccttt ttttatttat gatagacgga aagccaatca
    18241 ttttattatt catcaaaaga gatagaatag ataaaagagg agaatgattt attccgaaaa
    18301 gtgaaaacat ataacaaaaa attagaggaa atcaaatgaa tgaaaaagaa tgggatgaat
    18361 ttgctgaaga atattatgaa atccagcaag aatcgcaagt aactattgct gaagatgtaa
    18421 aaaattatct gaaaacggag aaagtcctgc ctgctgaaac agcagcagac gttgctggag
    18481 gatctggcag atttctttcc ttagcaaaag aaattaatcg ctatgatttg atcgattttt
    18541 cttcaggaat gctagaaaat gcaaaaaaag aagcagaaaa aaatgagttg ccaaatgttt
    18601 cctttatcaa acagtcgtta gaagaattta tccaatcaaa tgagacatat gaaatggttt
    18661 ttacagcagc aaatccagca ttggtacatc ttattcaatt agaaaaattg atgaaaaagt
    18721 caagcaaatg gtgcgtgata atcagagtag tggaatcaat cgatgatgtt ttttatccta
    18781 tcgaaaagca actaggaatg atagaagaag atcctaatac atcgccagtt gtaatggatc
    18841 aatttgaaac atacttaatt gatgaaggat tcaaagtgaa gaaaaaagat tttacttatt
    18901 ttacacagga atcaattact gaagaattga tgaagctata ctatgacgcg tacgcaaaag
    18961 atcctgttgt gaccaggtac attcgcaaac tattcagtga aaaacgagaa atccttagta
    19021 cgactaagct gacctataga ctgctccttt ggtccgcaga taaaaaaaga acctttcacg
    19081 actcgtgaag ggttcttttt atgattttat tatattttgt agtaacgaat atcattttcg
    19141 atctttgtaa tcgaaaaagg tacatctgaa gtatattctg cacattctcc gtgttcagga
    19201 agcgtctcac tgaaaatcgt ttcatattcg tcaacagtga tccgtgttcg agaatctagc
    19261 atctcttgat gagattgtgc gaagagatat tcttgatagt tttcttccag ataacctgta
    19321 aaaaattcac ttactgcacc agaaccgtag ctgaatagac cgatgcgatc tcctggctgt
    19381 agtgatttcg aattttccag tagagaagtt agccccaggt ataatgaacc agtgtaaaga
    19441 ttaccgattc gtcggctgta acggatgctt tcttcatagc gagccataag acgttcctga
    19501 ttttcttcgt ctgtttggtc taatacgctt tgcaatgcct tttttcccat cttagtatac
    19561 ggaatatgga aagcaatcgc ctgataatct tcgagtcctc gacccgacaa ttctttatgt
    19621 cgattccaaa ctttttggaa tgattcgata tacgtagaat tagataaagg accatcaaca
    19681 acaggaaatt cgctataatc tggacgccag aaatcataga tatcttctgt cagaaatacg
    19741 ctgtcgtctt caatcgataa aatacgcggg ttttgagtga tcatcatcgc aacagcaccg
    19801 acaccttgcg tcacttcacc accgcttgcc aagctgtaac gagcaatatc acttgctatg
    19861 actagtactt ttcgttctgg atgatttttg acatattctt tcgccatgtg caaagctgcg
    19921 gtgccaccgt agcaagcctc ttttacttca aaagaacgag caaaagattg gattttcagt
    19981 aaatggtgga taattaccgc actcgctttt gaatgatcaa tcccggattc tgttccgacg
    20041 atgaccatgt cgattagctc acggtctttt tctgttacga ttttgctggc agcatttgct
    20101 cctagtgtaa tgatgtcttc atttgcacga ttgactgcca tttggtcttg accaatccct
    20161 atatggtatt ttgcaggatc atccccacgg ctttctgcca actctgtcat atctaaatat
    20221 aaattaggaa taaaaaagga aagacgatca atccctattt tcatttcaac acctctttac
    20281 ttatgataaa aaacttactt tactaaggta tcataaaaag attaaaagaa atataaaaaa
    20341 gagaatattt aaggattgtt aaaatttaat cttagaaaaa aataactgga acaagagcta
    20401 tttgttttta cagcaaagaa tggtatattt ttgtaggagg tggcttactt gaaagaagtc
    20461 gttatgatag atgctgcaag aacgccgata ggaaagtatc gcggaagttt aagtccattt
    20521 actgcagttg aattaggcac acttgtgact aaaggattat tagataaaac aaaactgaaa
    20581 aaagataaaa tcgatcaagt aatatttgga aatgtcctgc aagctggtaa tggtcaaaat
    20641 gttgccagac agattgcttt gaacagcggt ctccctgtag atgtcccagc aatgacgatc
    20701 aatgaagttt gcggatctgg tatgaaagca gtgatcttag cacgccagct gatccaatta
    20761 ggtgaagcag aacttgtgat agccggcgga acagagagta tgtctcaagc acctatgctg
    20821 aaacagtatc agtcagaaac aaatgaatat ggtgaaccaa tttccagtat ggtcaacgac
    20881 ggattgactg acgcattttc aaatgcacat atgggattaa ccgcagagaa tgttgcaaca
    20941 caattttctg tgagcagaga agagcaggat cgctatgcct tgtcgtccca gttgaaagca
    21001 gcacatgctg tcgaagccgg tgtattttct gaggagatca tcccagtcaa gatttctgat
    21061 gaagacgtgt tatctgagga tgaagcagtt cgtggaaata gtacattgga aaaactgggc
    21121 acgttacgta cagtattctc agaagaagga actgtaacag caggaaatgc ttccccgttg
    21181 aatgacggtg cctctgtggt gatccttgca tccaaagaat acgcagaaaa taataatctg
    21241 ccttatttag caaccatcaa agaagtagcg gaggtcggta ttgacccaag tatcatggga
    21301 atcgctccaa tcaaagccat tcaaaaattg acagatagat caggaatgaa tttatcaaca
    21361 atcgatcttt ttgagatcaa tgaagcattt gcagcttctt ctatcgtagt tagccaagaa
    21421 ctgcagttag atgaagaaaa ggtcaatata tatggaggag caatcgcatt aggccatcca
    21481 attggtgcaa gcggtgcacg tatcttgact acattagctt acggattgct tcgtgaacag
    21541 aagagatacg gtattgcttc attatgtatt ggtggaggtt taggcttggc agtcttgtta
    21601 gaagcgaata tggagcaaac acataaggat gtgcaaaaaa aaaagtttta tcagcttacg
    21661 ccatctgaac ggcgcagtca attaatagaa aaaaatgtat tgacacaaga aactgcgttg
    21721 atttttcagg aacaaacact ttctgaagag ctctccgatc acatgatcga aaaccaagtg
    21781 agtgaagtgg aaatcccaat ggggatcgcg cagaattttc aaatcaatgg caagaaaaaa
    21841 tggattccga tggcaacaga ggaaccatct gtcattgcag ctgcaagtaa tggtgcaaaa
    21901 atctgtggaa atatctgcgc agaaacacct cagcggctga tgcgagggca aatcgttcta
    21961 tcaggaaaat cggagtatca agcagtgatc aatgcagtta atcatcgaaa agaagagctg
    22021 attctttgtg caaatgaaag ttatccttca atcgtgaaac gcgggggcgg tgttcaagat
    22081 atctctactc gggaattcat ggggagtttc catgcatact tatctattga ttttttagtg
    22141 gatgtaaaag atgcaatggg cgctaacatg atcaactcga ttcttgagag tgtggcaaac
    22201 aagttacggg agtggttccc tgaagaagag attctattca gtattttaag taattttgct
    22261 acagaatcat tggcttctgc ctgttgtgaa atcccattcg aacgcttagg gagaaacaaa
    22321 gaaatcggtg aacaaattgc caaaaaaatc caacaggcag gggaatatgc gaagcttgac
    22381 ccttaccgtg cagcaacgca caacaaaggg atcatgaatg gtatagaagc tgtagtggca
    22441 gctacaggaa atgatacacg tgcggttagc gcttcgatcc acgcctacgc ggcaagaaat
    22501 ggattatacc aaggattaac agactggcag atcaaagggg ataaactagt tggaaaacta
    22561 acggtgcctt tggctgttgc cacagtaggc ggagcttcca atatcctgcc aaaagcaaaa
    22621 gcatctttag ctatgttaga tattgattca gccaaggaac tagcacaagt aattgctgca
    22681 gtagggttag ctcaaaacct ggctgctttg cgtgcattag ttacagaagg aatccaaaaa
    22741 ggccacatgg gacttcaagc tcgttcatta gcgatctcaa ttggggctat tggtgaggaa
    22801 atcgagcaag ttgcgaaaaa attacgtgaa gcagaaaaga tgaaccagca gacagctata
    22861 caaatattgg aaaaaatccg ggaaaaataa aaaagcaata tctttagaag aataaagcaa
    22921 gatttacagt tattttattt actgcagatc ttgcttt
//
LOCUS       DAIGSZ010000046        21819 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.046, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000046 DAIGSZ010000000
VERSION     DAIGSZ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.046"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(106..552)
                     /locus_tag="NOB31_001869"
     CDS             complement(106..552)
                     /locus_tag="NOB31_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HCI0974073.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(579..755)
                     /locus_tag="NOB31_001870"
     CDS             complement(579..755)
                     /locus_tag="NOB31_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HCI0974074.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(917..1345)
                     /locus_tag="NOB31_001871"
     CDS             complement(917..1345)
                     /locus_tag="NOB31_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI0974075.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            1437..2297
                     /locus_tag="NOB31_001872"
     CDS             1437..2297
                     /locus_tag="NOB31_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HCI0974076.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLKQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            complement(2389..2739)
                     /locus_tag="NOB31_001873"
     CDS             complement(2389..2739)
                     /locus_tag="NOB31_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCI0974077.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(2754..4481)
                     /locus_tag="NOB31_001874"
     CDS             complement(2754..4481)
                     /locus_tag="NOB31_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HCI0974078.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEEAKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            complement(4695..5621)
                     /gene="trxB"
                     /locus_tag="NOB31_001875"
     CDS             complement(4695..5621)
                     /gene="trxB"
                     /locus_tag="NOB31_001875"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HCI0974079.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(5766..7199)
                     /locus_tag="NOB31_001876"
     CDS             complement(5766..7199)
                     /locus_tag="NOB31_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI0974080.1"
                     /translation="MGFRKDFLWGGATAANQCEGAYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQVKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(7199..8602)
                     /locus_tag="NOB31_001877"
     CDS             complement(7199..8602)
                     /locus_tag="NOB31_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCI0974081.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLSADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            8833..9735
                     /locus_tag="NOB31_001878"
     CDS             8833..9735
                     /locus_tag="NOB31_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCI0974082.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNDVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            complement(9775..11655)
                     /locus_tag="NOB31_001879"
     CDS             complement(9775..11655)
                     /locus_tag="NOB31_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0974083.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEAEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVSFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTEPAIYGITLPKK
                     KPFIYSMIGGAVSGIYLMASGTISYIMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDAIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(11751..12602)
                     /locus_tag="NOB31_001880"
     CDS             complement(11751..12602)
                     /locus_tag="NOB31_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0974084.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVIQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            complement(12928..14712)
                     /locus_tag="NOB31_001881"
     CDS             complement(12928..14712)
                     /locus_tag="NOB31_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974085.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRTTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVLVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            complement(14712..16463)
                     /locus_tag="NOB31_001882"
     CDS             complement(14712..16463)
                     /locus_tag="NOB31_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0974086.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTK
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            complement(16604..16828)
                     /locus_tag="NOB31_001883"
     CDS             complement(16604..16828)
                     /locus_tag="NOB31_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HCI0974087.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            17079..18665
                     /locus_tag="NOB31_001884"
     CDS             17079..18665
                     /locus_tag="NOB31_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HCI0974088.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETVEEIE"
     gene            complement(18731..20506)
                     /locus_tag="NOB31_001885"
     CDS             complement(18731..20506)
                     /locus_tag="NOB31_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HCI0974089.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVEKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGCLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(20719..21621)
                     /locus_tag="NOB31_001886"
     CDS             complement(20719..21621)
                     /locus_tag="NOB31_001886"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HCI0974090.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
BASE COUNT         6236 a         4711 c         3800 g         7072 t
ORIGIN      
        1 agctagaaga aagaataaga ttctttcttc tagctgtttt ttagttcttt ttttacgaac
       61 acaaaaaact gcggacaatc actgtccgca gtttaaatga taaaattaag attgtaatag
      121 ttctttcaca atcgcattca cttggtttcc atctgctttt cctttgactt taggcataat
      181 tgcacccata actttgccaa attctttcat tgatgaagca ccagtttgag tgattgcttc
      241 ttgaacaagt tgtcgaattt cttcatcgga aagttgttcc ggcatatatt tttcgactat
      301 tacaatttca ctttttactt tttcagctaa atcgtcacgt cctgcttctt caaactcatg
      361 caaagaatca cgtcgctgtt tcatttcgcg agacaacacc gttagttctt cttcttctgt
      421 caagtcgtga ccttctttaa tctgctcgtt ttgtatagat gacttgatca ttcggatgac
      481 ttgtaaagat tccttatctt tcgctttcat cgctgctttc atgtcatcgt ttaatctact
      541 tagtagtgac acactaccaa ctccaattca tcacagaact agaatttttt gcgttttcta
      601 gctgcttcag attttttctt gcgtcttaca cttggttttt cgtagaattc acgtttacga
      661 gattcttgta aagtacccgc ttttgacacg gaacgtttga agcgacgaag agcatcgtca
      721 agtgattcgt ttttgcgaac gactgttttt gacatgttaa ttccctccct ccgagcttaa
      781 aaagtaaccg taattgttat tgaaatatat ctcaaaaaac aagactgtcc tgtaaatatt
      841 atatctaatg ctgttttgac cgtcaaggaa atcttgcttt tttttaaaat tatcaaatgt
      901 tattttattt aaacccttat tgacaatttt cacatcttcc gaaaatctcg aatctatgcc
      961 cttcgatcgt gcatccacct agctgttctt cgaaataatt catcggacac atatggattt
     1021 ctttcgttgt tccgcacact gtacagataa aatgatggtg atggccgatt tccccctgac
     1081 agcaatgaaa acgaaacttc atttctccat ttaaatcggt ttcttccagt aaatcgatct
     1141 ctgcaaaatc atggagattc cgataaatcg tatcataact tacccctttg aattcctgat
     1201 tcatatagtc aaaaacttct ttagcagata cgtagcggtt acgcttcact aaataagtta
     1261 acaatgcttc tcttttttta gtatatttaa aaccgttatt tttcaatgtt tctaatgatt
     1321 gttcgatcaa tgtctgtttt ttcatgactt attcctccaa atcaaaatga ttacgaagta
     1381 cgcattctag agtatggtat aataaacata aaaaaaatgc aagtgaggtt ttatccatgt
     1441 cttccgattc tacagaaatc gttacttttt ttgtcatctc cgactctgct ggagaaactg
     1501 cgacaaaact agcgcaagct actatggctc agtatcctac cgttgagttc aacctattcc
     1561 gcagaacgtt cgtgacagat gaaaaaacat taaagcaggc attgcaagat gcattagaag
     1621 aaaaagcact tgtcctgcat acattaatca atcaagaact gatcgagata acacgttctt
     1681 tttgtgaaga acatcaatta tttagttttg atgtgatgac gccaccgata tcagaaattg
     1741 aacgtttaac cggtatcaag ccaattcggc aacctggtgc cctccattta ttgaatgaga
     1801 actatttcaa acggatcaaa gcaatggaat ttgctgtaaa atacgatgat gggaaagatc
     1861 ctcgtggttt tttagaagca gatgtcgttt tgctaggcgt atcccgaact tccaaaacgc
     1921 ctttgagctt gtttttagct aacaaaaatt taaaagttgc caatttacct ttgatcccac
     1981 aagcacatat tcccaaacag ctttgggaga tcgatcctaa aaaaatcgtg ggactaacga
     2041 ataacccaga tattttaaat aatatccgta aagaacggat gcgctcttac ggattaaacc
     2101 ctgatactgc ttattccgat atcgaaaaaa ttagagctga actcgatttt gcgaatgatc
     2161 tttatgaaaa actaggatgt gtagtgatca atgtggcatc tttatctatt gaagaaacgg
     2221 cttcgcttat tttgaatgct ttagacctag aagatcatag ttattatgga actgaaacaa
     2281 cagaaaaaag cgattaatca tttttgtctt tttcttaaaa aacactggag tgtgacaacg
     2341 aagaaatttc gttgtcacac tccagtgttt atctatttgc acctatcgtt attgatgttc
     2401 cacatgtttg agtgtctggt tcaaaatatc cagtacatga gaatcatcaa gactatacaa
     2461 aatcgctttt ccctcgcgat gagacttgac gacatgattt tctcttaata aacgtagttg
     2521 atgcgataca gcagactgct ccatttccac tgcttgggtg attgctgtca cattttgttc
     2581 cccgtctttc agatatagca gaattttaag acgagtggga tcactcaaca ttttgaataa
     2641 ttgactgact ttctctactt ttgatttttg cgtgtctggc aatccattca cctccaactt
     2701 gaaaaaagac tgacttctaa agtttaccac tttttccatc agtctcaagt tttttattct
     2761 tctgtcatct ttttgataat cgcttcataa gaggctactt tttcggctgc gtcttctgta
     2821 gagcttcctt ttacaccaat ataaaacttg attttcggct cagttcctga agggcggata
     2881 gcaatccagc cattttcttc caatgtatat ttcaatacgt cggatggcgg tgttgttagt
     2941 ttttctacgt ttccttcacg gtctgttctc gtcaattctt taaagtcttc tgtttgaata
     3001 acttttgctc cggcaaattc tgtcggtgct tctttacgga atttttccat caaagcagag
     3061 attttcgcag aaccttcttg tccgctcatt gtcacagaaa tcgttttttc tgcaaaatag
     3121 ccataggttt caaaaatcgt ttgcaagccg tcatacaacg ttttgccttg ttttttatag
     3181 taagctgcta cttctgctaa taaaagcaat gcttggatcg cgtctttatc gcgaacaaaa
     3241 ggtttaacta aataaccata actttcttcg aatccaaaca taaaagtatg tgaatggtct
     3301 tcttcgaatt gttggatttt ttcagcaatg aatttaaacc ctgtcaacac attgaacatg
     3361 gtagcaccgt agtgttccgc aattgctgta ggcaattcgc tggaaacgat tgatttcaat
     3421 accgctgcgt tttctggtaa agtgcctctt gattgatgtg cttccaaaat atattgagca
     3481 aacaatgccc cgatttggtt cccagtcaat acttcataag aaccatctgg caaacgaacc
     3541 gctgcgccta aacggtctgc atcaggatct gttgcaatca gcaagtcagc tccttctttt
     3601 tctccaagtc gtatagcata ttcaaaagct gaatgttctt ctggatttgg cgatttgacc
     3661 gtagtgaaat ctggatctgc cacagcttgt tcgggaacta gtacgaattg ttcgaatcca
     3721 gcttgtttca acgcacgttc gcccaacatt ttccctgttc catgaagtgg cgtgtacaca
     3781 agtttcaaat ctttccccat tgtttctacc aattcacgat caatcgtcac tgctttgatt
     3841 tcttctagat aagcagcgtc cacttcttct ccgatgatcg tgatcaaccc gctatgttta
     3901 gcttcttcgt cagataatac ttcgactttt agcggattgc tgacttcacg gacatatttc
     3961 gtcaatgcat ctgcgtctgc aggaggcatt tgtccgccat cttctccgta gactttatat
     4021 ccattgtaag ccgctgggtt gtgagatgca gttaccatga ttcccgcaaa cgtcttcaaa
     4081 tgacgaactg caaaagaaag ctctggtgtt ggacgcagac tttcgaatac ataagacggg
     4141 atattgtgat gtgccagtgt tttggctgct tccattgcaa attctggtga ctgatggcgt
     4201 gagtcataag caatagcgac acctcggcgt tttgcttctt caccttgtgt atccatgaaa
     4261 cgtgctagtc cttctgttgc ttgtcttacc gtatagatgt tcattcgatt gatcccaggt
     4321 cctaagattc cccgcatgcc tgcagtaccg aattccaacg gtgcataaaa agcatcttca
     4381 agtttttcag gatcttcacc cagatcattt aattgttttt ttaagttttc ttctaaattt
     4441 tcttcatgta cccattgttc atacacttgt tcccaagaca tgaaaataac acctctttct
     4501 gaaatatggt tcttaataag tatagcattc acttattaga tatgaaagta tgaggaccaa
     4561 aaaacgctta aatcaagaaa ggattctttt atcaaaaggt gttggacgtg ttcgcataaa
     4621 tcagattcag taaatttcac gcgaaaaaaa agagtaaaag aacaattgaa cccgttcttc
     4681 tactcttttt aaacttatgc agttgtttct tctaaagatt ccaagtattt atacacttgt
     4741 tgtccagcaa taccgccgtc accaacagct gtagtgattt gtcgcaaatc tttttcacga
     4801 acatctccga tggcaaaaac gcctggcata ttcgttttca tttcgttgtc tgttggaatc
     4861 cagccagctt cgttcgtcaa acctgcttct ctaaaaggtg cagttaatgg atccagtcca
     4921 acatagatga atactccgtc tgctgctaaa tcaaattcat tgccggtttt gacattacgt
     4981 gctttcacac ctgtcactac catttcgttt ccaacgattt cgtcaacgac tgtatcccac
     5041 ataaaggaaa ttttttcatt tgcaaatgca cggtcttgga tgatcttttg tgcacgtaat
     5101 tcatctctac ggtggacgat cactacttca gaagcaaatt gtgtcaaata gatggcttct
     5161 tctactgctg agtccccacc cccgatgact actagacgtt tgttacggaa aaacgcacca
     5221 tcacagactg cacagtaaga aacgcctcgt ccagcaaatt cttcctcgcc aggtacgcct
     5281 aatttacggt ggatacagcc tgttgcgata atgactgttt ttccttcgta acttttatct
     5341 tcacagatga cttctttatg gctgccgtga tccttgatat cttgaacgat tccataagca
     5401 ttttctgtcc caaatcttga gacactttca tacatcttat aagctagatc ggggcccatg
     5461 atcgaatcga atccaggata attttcgatt tctgccgtat tgttcatttg gccgccaggg
     5521 gcaccttgtt cgatcatcaa tacggataag tttgaacgtg aagcatataa agcagcagtc
     5581 atcccagcag gacctgcgcc aataacgatt acatcataca tatgtagatt ctcctttact
     5641 taatcaagta agcatacttt acagccaatg cgaaaaaaag tctattgttc tgcttgcgtt
     5701 tctcgaatag ctttattata ctcgaaaaat ccgctgaaaa acaatagact tttataaatc
     5761 attgatcaat cgttcgaaag attttctcca tttgaatcaa ttactttttt ataccagttg
     5821 aatgattttt tctttgaacg ggctaatgtg ccatttcctt ggttatcacg atcgacataa
     5881 atgaatccgt atcttttctt catctcaccg gtaccagctg atactaaatc aatacatccc
     5941 caagtcgtat agcctaatag atcgactccg tctagttcta ctgcatcctt catcgcctgg
     6001 atatgcgctg ccaggtaatc gattcggtaa tcatcttcca cataaccatt ctcatctggc
     6061 gtatcgactg cacctaagcc gttttctaca ataaataatg gtttttgata acgatcataa
     6121 atatcattca tcgttattct caagcctaat ggatcaattt gccaccccca ttcacttgct
     6181 tgcagatatg gatttttgac agaagcaaag atatttcctg cagtctgttc caagagttcg
     6241 ttgtcggtag tcgaaactcg ggaagaataa taagaaaaag agataaaatc aacagtatgt
     6301 tctttcagca atgcggcatc ccctggttcc atttcgatct gaatgccatt tcgttccatt
     6361 tctttcaatg cataagctgg gtattctcct cgtgactgaa catcaatgaa gaaataattt
     6421 tctcgatctg attttctaga agcccaaaca tcttcaggat tgcaagtgta tggataatat
     6481 gctcctgctg ccagcataca gcctactttg ttctccggat ctacttcatg agcaatcttc
     6541 gttgcgatgg cacttgcaac caactcatga tgtgccgctt gatatttgac ttgttcttcg
     6601 ttttctcctt cttcaaagta cagtcctgct cccatgaatg gtgcatgaag gatcatattg
     6661 atctcattga atgtcagcca gtatttgaca agtcctttat atcgattgaa gatgactcga
     6721 cacagatttt cataaaaacc aacgagttct ctggaacgcc acgcaccata ttctttgatc
     6781 aaatgcattg gacaatcaaa atgcgtaatc gtcacaagtg gctcaattcc gtgcttttgg
     6841 cattctttaa agacatcctc ataaaatttc aagccagctt cattcggctc tttctcatcc
     6901 cccattggaa aaatacgact ccaggcgata gacattcgat aagtcttgaa ccccatttct
     6961 gcaaacaaag caatatcttc tttataacga tgatacatat cgattgcaat ttttgctgga
     7021 taaaaatgat cctcatcaaa ttcaaacatt tttttctttc cggtgataac aggaaaacgg
     7081 tcttttccga ttggcacaac atctacgttt gctagtccgc gtccaccttc atcataagcg
     7141 ccctcacatt gattggctgc tgtagcaccg ccccataaaa aatcttttct gaaccccatt
     7201 atacttcctc cattatatgt gtattacctg ataattctct tgccagttca tcttgaactt
     7261 cgattccttc ttcttttaat cggctgattg tttccttgaa ttgcggtaaa tactgctggt
     7321 gtgcaataaa caactcatcc atgatccgtt ttgctgtctt tcctgatcgt ataagtggat
     7381 tgatcgtaaa cgcctgtaaa gctgtcccat aatcaccagt cacagctgct tcgatcgtca
     7441 gcaattccat attcttcatt acttgcaacc agcctctttc agcagcagga agagaaccaa
     7501 acgctacatt tctcgctcct tgtgcgccaa cataggcagt gacttctaca acacaatctg
     7561 ccgacaggtc aggaacagct ccatcattct ttgtagatac aacgatctgt gtttctttat
     7621 ttccatagat tgaagcaatc gtttcacagg cagcgtctga ataataagcg ccacctcgtt
     7681 tttgcaattg ttcaggttta tggtctaatt ctggatcttt gtataattca aatagctctg
     7741 cttctgtttc tttcacttgc tgcgctcttg taccaatcgt ttgatattct tctaaagcat
     7801 gttccagcat ttcttcttca cgatagtaat agcggtggta gccacaaggg atcatgttca
     7861 tttgttttaa ttgttctttg aaaaacggga tatcaaagat atttttcggt aatccattat
     7921 cttcatcgta taaacgatca atcaattctg ccgtgcggtc atttccttta ttatctgcta
     7981 ctttgtgcca atggaaatga tttagaccgg caaacttgta gatcagctct tcttttttct
     8041 tgccaagcat tgctggttct gtcatcatcg ccatcactgg cacattgcat aatccaatca
     8101 ctttatccca tttgccatat ctgataactg cttctgtcac catcccactt gggttcgcga
     8161 aattgatcag ccaagcattt ggacataaac gcttcatgtc ctcaacgatt gccaaaacga
     8221 ctggaacggt acgaaaagct ttgaatatcc cgccagcacc atttgtttct tgcccaatca
     8281 tcccataata actagggatc cgctcgtctt tgattcgtgc atctaattga ccgacacgaa
     8341 actgagtcgt aacaaaatcc gcatctttca atgcttcttc ccgatccaga gttgcataga
     8401 tcttgacttc atatggagaa gcatcccaca tacgctgaga catctgacta acgatctcaa
     8461 gcttttcttt tccttcttct acatctacga gccagatttc tcgtatcggt aattcctcat
     8521 atcttttgat aaatccttcc atcaactcag gggtgtaact gctgcctcca ccaatcgtag
     8581 cgattttgat tccttttgcc atgttctcac tcctttactt ttttacactt tcattatctt
     8641 ttttgtaaac aaaacaaaca atagaaatcc gtttctttcc agtaacattt acaaaagtta
     8701 ctgttttcta gtggattttt gtaaatatct tgtcaaaaaa agcctatttt aagttatata
     8761 gtataaatcc gtttacaaaa cattttcaaa aaagttataa tttacgtaaa aaaataagaa
     8821 gaaggtatct acatgttatt acgtgaaaaa atcaaagaaa tctccttttc tccttcagaa
     8881 aatgaagtga tccagtttct cttaagcgat tctccagcac ttggcgaaat gaccatccaa
     8941 gcgatagctg agcgatgtta tgtccacccg tctacactca tccgtgtagc aaaaaaaatg
     9001 ggttttgatg gctgggtcag ttttcgtaat gcttttttag ctgaaacagc ctatcttgaa
     9061 gggaattttc aagacgtaga tgcgaatctt cctttttcca ccacagacgg tattatgaca
     9121 atcgcaaata aaatggcttc tttagaacag atgacgattc atgatacact ttctctcatt
     9181 catcatgacc aactgcaaaa agctaaatat ttactgctcc aggcaaaaaa aatcgtgatc
     9241 ttcgccagta actcgaatac tttgatttct caagatttca tgctgaaaat gaagcgcatc
     9301 aaaatggatg tcacaattgt caccactttt ggtgaatcat tctatgaagc gtacaattgt
     9361 acgagcgata tgtgcgggat tctgatttct tatacgggtg aaaacaatgt gatccttcgt
     9421 accgcagaaa tattgaaaca aaatgatgtt ccaattttag ctttgaccag tatcggtgat
     9481 tcaacgctat ctgcaatgag tacagccgct ttgcgactta cgacacgcga gcgactgtat
     9541 tcaaaaattg gtaattttac gatcaataca tcaatttgtt atcttctaga cgtgttatat
     9601 agttgtgttt ttgcagaaaa ttatcaacag aatttagtcc atctaatttc tgtcggtcaa
     9661 aaattcgata aacgccctat cagctcagcc atcatgaaag agcctttcaa ttttgaaaat
     9721 aaagaagtgg aataaaaaga atagttaagc ctagtccatt cttcacctaa ccgttcaggt
     9781 cagtgcggtg ataagtgcat cgtctggccc gaccgtctcc ccttggtttt ccaaaatatc
     9841 caaataatcc gtgtaattgg tgacgatcac aggtgtttct aaactgtatc cttccttttc
     9901 gattttcttt ttgtcgaagc gtagcaacag atcgccttgt ttcactcttt ctccttgctg
     9961 cactaagctt tcaaaatatt tcccttccaa ctgcacagta tccaatccga catgaatcag
    10021 caattccagc cctgtttcag aaaccattcc gattgcatgt ttcgtcggga acagggtcat
    10081 aactgttccg tcaaaagggg cacgtacttc tcctttttca gggtagatta agattcctcg
    10141 acctagtgtt ccttgtgcaa aagctgcatc cttcgctgca tttagtggag cgatttgtcc
    10201 ttgtatcggt gtttttacaa tttctttacc tgattttttc tgtatagcat ctgtttcacc
    10261 tgcttcatcc ttccaaaaga aaaaagtcag cgaaaacccg attaccgaag caatagcaat
    10321 gccgataaac gcttgaaaca taccactggc gtctgtttcc gtgatgtagt ttaccacccc
    10381 aaaaatccct aatccgccca ttatgtagct gattgttcca gatgccatca aatagattcc
    10441 tgaaacagca ccaccaatca tcgagtaaat aaatggcttc ttcttcggta aggtgattcc
    10501 ataaatagcc ggttctgtta cgccgaagat tcctgaaatc acagctggca tgcaaagcgc
    10561 cttcattttt tgatccttga acttgaaata catcgccaat accactgctg tctgtgcaaa
    10621 actcgcgcca taaacgccta ctaacatctg actccaccca ttttgcgcta gctgcataat
    10681 cgcaagaggg ataatactcc aatgaagtcc gaaaatcacc agtacttgcc aaagaaaccc
    10741 tagaactgca ccatacacag ctggagaaaa gtccatcaat gcttggaatc ccgtgcttaa
    10801 tagatctgtc agtatactga caatcggacc gataatcaaa aagccagcag gaagtgcgat
    10861 taataacaca gaaaaagaaa ccaaaaaggt ctggacgact gcaggaatcc atttcttggc
    10921 aattttttgg acttgtccgg caaatgcgat aatgaagata acaggtacga cgctactagt
    10981 ataactgctg cccacccatg ggatacccaa aaatgtttca taagccggaa gacccagcaa
    11041 gctataaggc gcaggactgc catcagggaa accactttgt agtgctgctc cttgtacagt
    11101 cggataacaa agtgctgcac caatcacgag ccccaccatc ggattcagat gaaatttttt
    11161 cgctgctgtg taccctaaga tcactggcat gaaataaaaa attgcatccc ctatcccatt
    11221 cagcatgatg tacgtacccg atccttcagt ataaaatttg agaaacaaga acaaagcatt
    11281 taatcctttg accattcccg ctgcagccaa agcacctaaa aaaggctgga aacagccact
    11341 taatatgtcg attaatcgat tgaacagatt actacttgaa gaaacctctt cttctgcttc
    11401 atcggaaatc ccggctactg tcagtacttc tgcatagaca tctggcacat gattcccgat
    11461 tacaacttga tattgcccgc cgcttttcat gatggtgact atcccttcca tctttttcaa
    11521 aacatcatcc tttgctttat tttcctcctt tagtttgaaa cgaagtcgcg tcacacagtg
    11581 tgtcaagcta cggatatttt cttttcctcc gatattcttt acgatgtttt ctgctaattc
    11641 ctggtatttt cccatttcta ttccctccaa ttaattagtg gaaggtttag ccaactgaat
    11701 gtcactaccc ttatttcata cgttcttgtt aatttgtcct ccttttttat ttatttacaa
    11761 cgattctcat gcactaaacg cgcagtatgg atcgttaaat acattttttc atccgtggac
    11821 atctggtagt cgaaagcccc ggttaaaaag tctgctattt tctcaacgca accaaacgta
    11881 tccttatatt ttttttgaat aacttggaac aattcctcag aaacttctcc atcttctgat
    11941 ttcgctccat ctaggacacg tgtcagaaaa aaacgcaggt gtgtgacgaa tcgaaaaaag
    12001 tggactgaat cttcatcaaa tgtaatctta tagtaatagc ggacgatatt taaaatatcc
    12061 tgtattgttg tggtaaacag gtaggtattg tcttgctggc tttgaatgcc ttgtgcattg
    12121 actaaatgca atgcgataaa tccggcttcg tcttctgata acttgatgtg gtatttatcc
    12181 gagattttct tcactgtttt tttcccaatg gcatactctt taggaaacag ttgtttgata
    12241 tcatacagca atacatttgg cacaaagatc cccatttttt gacgttcgat agctgtatac
    12301 aagtgatccg tcaatgaaat atacacagaa tcatttaaat ggacttgcag agcctctttt
    12361 gtatattcaa tgatttcaca agaaatttct aagtactcaa gaggaatcgc ttgtgccaat
    12421 tcttggaact gttgtgaaag tccgtcattt gtcaactgaa attttttgtc gatgcatgag
    12481 tcaagaatcg ggtcacccac cttctttttg aatgccaatc cttttcccat cacaatcatt
    12541 tcccgatctc tttcatccct tgttattacg acgttgttat tcagtacttt ctcaatcagc
    12601 atgttttgct cctttccatg atatataggg ctgtatccaa aacaaaaaga aaaacccaaa
    12661 aagccgtcca tgaaaccatg ggagactcat caggtttagc ttgcatcagg caatcactat
    12721 ccaagttgta tcgttttctt tatattatcg aaagcaaacg attttgtcaa cgctttctta
    12781 ggggctatta ggcacttctg actagctgac gtcgtctttt ttaaatctgg taactacgac
    12841 actaactctc acagatgaaa aatatgggaa gctatgtttt attttcactc tagtgcttag
    12901 gtcaaaatgc tactgtcaca acatctttta tataccacta ctttgcagtt tgtacatatc
    12961 tgcatacaaa ccattttgcg ctagaagtgt ttcatgattc ccgcgttcta ctatatgacc
    13021 tttgtctaaa actaaaatca attctgcatc tcgaatcgtt gacagccgat gggcaatcgc
    13081 aatcgttgtc cgtccttgtc gcattttcgc caatccttct tggatcaatc cttctgtttc
    13141 agtatcgata tttgctgttg cttcatccaa tactagaatt ttaggatcag tcacgattgt
    13201 tcgcgcaaaa gtgatcagct gtcgttgtcc actagaatag ctggcaccat gttcgatcac
    13261 ttttgagtga tatccttttg gtaattcatc gatgaatttg tttgcttgaa caaactcagc
    13321 cgcatggcgt atctgttcgt ctgtgatagc tggattcatc atccgaatat ttcctgcgat
    13381 atccccataa aacaagaaag catcttgcaa gaccagcccc attttcttac gtaactcttc
    13441 cattggatat tctcgaatgt catgatcatc aatcaatatc tgaccttcat aaaattcgta
    13501 aaaccgcatc aacacattga tgatcgagct tttcccactt ccggtgtgtc ccactaatgc
    13561 aacggtttct cccggattag caacaaaaga gatattgttt aatacattgt gctctccatc
    13621 ataagaaaag cttacattgc gaaactcaat cttacctgaa gtaatcattt gatctgctcc
    13681 agggttttgt tgtggtgcat attcttccgt atccataatc ttcaagatac gactaccagc
    13741 aaccatccca tctgtgaaga tgctcaaaaa gtccatcatt tgagacattg gattaaaaaa
    13801 tccctggaca taagtcgtaa atgcatagat cagtccaact tctacgggag aatgcaacgc
    13861 atcgatccca aataaagtca acgccaacgc aatcgccaat gcatatagaa aattgatgat
    13921 cggacttaac agaatcgaat tcgttttgat catcgcatag cgcgtgtcta aatactcatt
    13981 gttcacttgt tcaaattctt tagctaaacg agcttcttgg cgaaactgct ggataatacg
    14041 catgccggaa atcgattcat tcaattttgt attcagctga cttaattttt cccgcatatt
    14101 tcggtaaata cgagaactaa atttctggta ataccagatg acaattccta aaatcggcaa
    14161 gaacaccaaa gtccacaagg caatttctcc attgatttga aacatggcaa tgaatgaaga
    14221 aacgactgca aagatcccag tcaataccat caaaaagacg taccaaaatt caaatagcgt
    14281 ttctgtgtca ttcgtcactc gagaaacggt tgatcctgcc ggtgtctgat caaaataacg
    14341 catacctagt gtatgcagct tttcaaataa ttttacccta atatactgat aggtcttcaa
    14401 tgaagccatg gaatacaaat accattggaa aaaccaaatg atacttttta ctaggactcc
    14461 aaataagtac ataccagcaa aaaacaaaat aacttgtgtc gtagccgact gtttagccag
    14521 atgatcatcc ataaaagttt ggatgatcct tggcaatagg acattgatca cagacagagc
    14581 aaacgcaaat aagatagcaa cgatgaacgt tgttctaaaa ggtttggcga acttcatcag
    14641 tcgtttgatg atctttttct gttctttaag tggaatcgat tttgtccatt ccgattgata
    14701 attttcatcc atcaggcctc gcctccttct atcttcgctt ctaattgctg tttctcccac
    14761 atttgttcat accagccgcc tagtgcaagc agctcatgat gggttcctcg ttcaatgatt
    14821 ttcccttgat cgacaacaat gatttctttt gcatgcatca cgctacttaa acggtgagct
    14881 gcaatgatag ttgttttctc ttttcttatt tcttttaaat tatgcaagat agcttcttct
    14941 gttttggcat ctactgcaga aagtgcatca tctaatatta ataattcagg atttttgatc
    15001 aatgctcgag caatcgaaat cctttgtttc tgtccgccag ataaagagac tccacgttct
    15061 ccaactaagg tatcataacc ttttggtaat tccttgattt cattgttgat aaatgctaaa
    15121 gaagccgcat gctctacttc ttcttctgaa agttttggat tagaaaaacg gatattatct
    15181 cgaatggtca tcgaaaacaa gaagtgatcc tgaggcacat agccgattga tcctaataaa
    15241 gcattcaatg aatattcttt gatcgaacgt ccgccaaatt ggattttccc ttgataatca
    15301 tcgtattcac gcatcagtaa tttgatgatc gttgtttttc ccgcaccagt tttcccaaca
    15361 atacctaatg tttctccttc ttggattgca aacttgattt gttctaatgc tggtgattct
    15421 tctttcggat aattaaaaga ggaaatagct acattcagct cgccttttgc cggggtctgc
    15481 actgcaccca gttgttccac gatatgcgtt ttttcatgca aaagttcatt gacgcgatca
    15541 taagaagcat ttcctctttc caatacgttg aacaatcgac caatcgcaaa catcggccaa
    15601 acaagcatac cgatataact aataaatgag accatctgcc cgatcgagat cgtgccttcc
    15661 aagacatact ttccacctaa aataattgtt gcaacataag acagaccgat aatcaaggta
    15721 atgaatggat caaataagga gtctagaaaa ttgactcgtt tgtttttaat aattgcatct
    15781 tcaatctttt cttcaaaatc cgctagatct tctttttctt gtccaaatgt tttaatgact
    15841 ttgatcccag tgatactttc ttgtgtctta tcattgatac tagaaaaagc ttcttgcgaa
    15901 tcacgaaaag catcatggag tttcgacccc agcactcgtg aagtgacggc cagcaaaggc
    15961 agaggaatca gcgcaatcag tgttaagcgc caatcaataa acaaaatcat cgcaatgatc
    16021 gttgttccgc ccgtaatcac tgaatctgca aaggtcaaga taccagctcc tgctacattc
    16081 tggatcgcat tcaaatcatt cgttgcatga gccatcaaat ccccagtccg atatttttgg
    16141 taaaagagat tgtccatttt tgtaaaatgt ttgaataact gctgccgaag ttctttctcc
    16201 aaccgagctg cacttcccca aatattcgtc cgccagatat aacgaaaaag atattgtaag
    16261 aaagcagcga taatcaatag gaagatccac ccgaaaatga tctttactga taaattttta
    16321 tcggcaatct catcaatgat gatcccaatc acttttggag gaactaactg taccaaggcc
    16381 actgcgaata gcgagaaaac cccaattaaa taatgtttct tttcctgacg aaaaaaccag
    16441 cctaactttc taaaaatcga cattttactc ctcctttgtc tttatcaaga gcctaggatt
    16501 gtctgtgctt gtctttttgc tgaataatct gaatagtcta acaaattaca aaataaaaaa
    16561 cggactgaaa aaatcagccc gtaaaaagtc gttgggtcag aacctatttt ttcccttggt
    16621 tcttcatttg ctgcatcatc tggcgaattt tcttctcaga tggtttttgt cccattgaca
    16681 tcatcattga tcgcaacatg tcctcattaa cgggaggatt tttttctaaa tagtctttca
    16741 tatatttacg cgctaggaaa aagccaccta ctgcgccgat tagcaaagca ataatagcaa
    16801 taagtacgac aatacctgtt gataacatat aaatctctcc tttctatttc cgaattgctc
    16861 tcaatgactt attttactaa agtttattga aaaaagaaag gcgtattctt tagtttcatg
    16921 caaaaaatag tggttttttt agaggagaac aaaatttctt tcgtcatcta gcaagacgag
    16981 ccacaaaaaa aaattaggca taccgaatat ttttctttaa ttttttcttt ttgaggtgta
    17041 gaatgtaatc gtagataaat aggaaaggtg gttttttctt gaataatcaa tccaataaac
    17101 aatttcataa gcatcgactt attgaacata caaatggttt atctttagct gaagtaaatg
    17161 gaacagttga tgtaccaaag gggaaaagtt tttttaaaac acttcttgct tactctggac
    17221 caggtgcatt agtagcagtt ggttatatgg atccaggtaa ctggtccact tcgatcactg
    17281 gtggacaaaa tttccaatat ttattgatgt cagttatttt gatgtctagt ctgattgcta
    17341 tgcttttaca gtatatggca gcaaaattag gaatcgtaac ccaaatggat ttggcccaag
    17401 caatccgagc acggacaagt aagacattgg gtgtcatttt atggatcttg actgaattag
    17461 ccattatggc aacagacatc gcagaagtca ttggtgcagc aatcgccctc tacctgctct
    17521 ttgatattcc attagtgatt gccgtcttta ttactgtatt agatgttttc gttctcttac
    17581 tactgacaaa agtcgggttt cgtaagatcg aagcactggt tgtctgctta attttcgtca
    17641 ttttattcgt ttttgtctat caagttggct tgtctaaccc agattggcac agtttatttg
    17701 ctggctttat ccctaacagc catacattct ccgactcacc tgtcattggt ggcgaaactc
    17761 cgctgactgg agctttaggg attattggtg caacagtcat gccgcataac ttatatcttc
    17821 attcagcagt ttcacaaact cggaagatcg atcaccaaga cgaagaagat gtagcacaag
    17881 ctgtacgttt ttctacttgg gactctaata tccaattgtc gatggctttt ctagtcaatg
    17941 cgctgctatt gattatgggt gtcgctgtct tcaaaaccgg ttctgttcaa gatccttcct
    18001 tttttggtct gtatgaagct ttatctgatc catcagctat gagcaatggt atcttgattg
    18061 ctgtagcaaa atctggtatc ttgtccactt tatttgctgt agcacttctt gcttctggcc
    18121 agaactctac tattactggt acgttgaccg gtcaagtcat catggaagga ttcatccata
    18181 tgcgtatccc gatttggcta agaagactgg tcacacgatt gctttctgtg attcctgtat
    18241 tgatttgtgt tttgtttaca agtacaaaag gaacgatcga agaacatacc gctttgaata
    18301 acttaatgaa tgaatcccag gtgttcttgg cttttgcgtt gccgttttcg atgatccctt
    18361 tactgatgat gaccaacagc caagcggaga tgggtagccg atttaaaaat tcattcatcg
    18421 taaaacttct tggctggttc tctgtgatta gtctaactta cttgaactta cgaggattac
    18481 caggacagat cgaaagtttc ttcggcgagc aagccacttc cgctcaacta gcattggctg
    18541 atcacatcgc ttatgtaatc attgttcttg tccttctcct gttggcatgg acgattggtg
    18601 atttatataa aggaaacaaa aaatatgaac agcgtttgca ggaaacggta gaagaaatcg
    18661 aataaaaact gatttttcca cacaaagacc cttgatagtt aggttaaaaa tctagctacc
    18721 aagggtcttt ttatttagaa gataaagctt ttttcagatt taatttactg aaaactagca
    18781 tgcttgttac tacgatgaat tgcgttaacg gcacgcctgc gccagtgtag acacttaaaa
    18841 aataatcctt tttttctggc gcataagaac aaaaccacga gacaccgaaa agaaaaacca
    18901 attgtgtcag tattaatccg gtgaccacaa tcaaagagga actataatag gcacgatcag
    18961 cttttgcaaa tacggttcct agtatcataa gtaatatccc tgctattgaa gcaatcagca
    19021 cgggaatagc cagaacttgg taaattttta tgatgacatt cgcgactttt gctgattttg
    19081 ttaattggaa attaggtgtt ctcggttcat tactatcgat ccaattctcc attagcggaa
    19141 ggtttaataa ttcttgagcc tgtttgactt gttcttgcgt tccgaaacta taatttcctc
    19201 cttgatggaa atctttatat cgccatgcat aagcgtatcc tgattgaagg aaatcgaata
    19261 cgattggcag atcactcatc gtctttccat ctcctgatcc catcagatag aactcttttt
    19321 tctttttgat ggttcccttg tgataggctt cttctaattc ttggttgact tttttccaaa
    19381 aatcattggt ttcttttgca ttgttttggt aataaccaga ttcgcttacc acatctcgca
    19441 atgcccaaaa gatgatatct ccgggtaatt cttttacttt tccaccttga gtccacgcgt
    19501 gagtcgtata taattcgtca atacgggtag aaacagtatg gaatgtagga gatgcggcta
    19561 atgctttatt tagtgcagca tgtgagaccc atatctcact gttttcttta ttcaagttcg
    19621 tttcatcatc tattcggatc agttgtttca tcaaacatcc aaattctcca ctggaacggt
    19681 cattgatggt tgcaataccg tatgttgtct catttttata ttcgatccac tgatagacga
    19741 tggaaaagcc aactatagga agtaaaaaca atgaaagttt cagccattcc cgtttcgaga
    19801 gaagaaagag tcgttttttt aacttctcta cttctttgaa agaaaagtct tgccctagca
    19861 agatctggac gaaactgata cccaaagcta ctacagtaaa aggaagaagc cagatagaat
    19921 cttcgcgaat gaaccaaaag aaaggaaaag cgacagaaag ccctaaaaac catggcagca
    19981 attttctgct agaaccgtat ttgcggtaat aaatagctag taaacaagcg ataatgatct
    20041 caacagccgg aatcacgagg gcattacgat acgttcgagt ggaatattca tgtgtaaaac
    20101 taatcggaga aaacaaaaaa taaaaataga aacttaaaag aagatacttg ttcttcacga
    20161 tcggtttaaa cgcgagtgca accaatatac tggcaaaaat actgaacatg ccgaacaaaa
    20221 ctgcataaga aagatgcagt ttatgtgcaa gtactaaaaa taagctgtag gagattcctt
    20281 tggaaagtgt tgtagtcgta tactccccta gccatttacc gtccaaaata ttttgagcat
    20341 agcgaatcag cagctggtca tcataggttg ccgacatgtc tgttccatag attgctttac
    20401 tatataaata caaacgaata attgtaaata atagggctat gccaagaata aagtatgtat
    20461 gtttcttttt tagttggttg atcaagggtt ttaaagtgtt cagcatcttt tcgtccttcc
    20521 aatcacgttt tgccacttgc ttgtgaaact tttcgttttt ttacttttct accagtatac
    20581 cctgtttgtc taaatttaaa aagagggggg agaagatgca tgatgaaaaa gactgcaaaa
    20641 agcactcctt tgtttcttaa acaaaaaagg acaaggcaat gtgcctggtc cttttttgct
    20701 gctgtcagat agaaaatctt agagtatcac ttcttctgct aataactcag gaaacacttc
    20761 tggatcgaat atttgtgctt tgaacatggc gatttctttt ccatatggtg cgtaagcttt
    20821 ctttttatct ttgccgacat agggagtttc caagattttc gaaatattgt caaacattgg
    20881 atcatggacg atcttattca gcgtgtcgaa tccgattgtt ccaaaaccaa tattggcgtg
    20941 ccggtcttta tgcgaacctt gcggattttt agaatcattg atatggagta ctttaagccg
    21001 atctaacccg atgatcttat caaactcttc cattacacct gaaaagtctt ctttaatatt
    21061 ataaccggca tcattcgtat gacaggtgtc aaaagtaacg gataattttt cattcaattt
    21121 tactccatcg atgatttgcg ctaattcctc aaatgttcga ccgatttccg tacctttacc
    21181 tgccattgtc tccaaagcga tttgtgccgt ctgttctttt gtcaaaactt cattcaagcc
    21241 ttcaataatt ctagcaattc cggcttctgt tcctgcccct acatgagcac ctgggtgaag
    21301 tgtaatttga gtagcgccta aagcttccgc acgaacaatc tcttctctca gaaattggac
    21361 ggcaaaagga aacatttctg gtttgatcgt attccccaaa ttaatgatat aaggggcatg
    21421 aacgacgata tttgttagac cgttttctgc catgtacgct tttccggcat caatattcat
    21481 ctcttcgatg gcttttcttc tagtgttttg aggggcgcct gtatagatca taaaagtcga
    21541 agatccataa ctggctgctt cttctgctgc tcctaacagc attttctttc cgctcatgct
    21601 gacgtgtgag cctaataaca tggatggatt cctccttgaa aggcaattgt tactaacaat
    21661 tcctatatat tggtaagatg atatacaaag aaaatgattg atttttcttt gccctgttct
    21721 ccatagtaac tgaaattttc tctaaagaaa agcttaagaa ctcttttata aaaaagatca
    21781 ttttctcacg ttttaactcc tattatttgt caaattaag
//
LOCUS       DAIGSZ010000047        21813 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.047, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000047 DAIGSZ010000000
VERSION     DAIGSZ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.047"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..102
                     /locus_tag="NOB31_001887"
     CDS             <1..102
                     /locus_tag="NOB31_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HCI0974091.1"
                     /translation="DRQTNWSKKLHQDRFKFVEKYKEILDEYMEGSK"
     gene            99..485
                     /locus_tag="NOB31_001888"
     CDS             99..485
                     /locus_tag="NOB31_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974092.1"
                     /translation="MIPRFRSWYTPFKGKTIGQEMKYGQAGRLITHAEMAPDKYVLMQ
                     STGLKDKNGVEIFEGDVVLVNVSNGFDHLVNEKTVVQESEFHSGLVCKSLISGMEYRI
                     FSHQKMGYEYEVTGNIHENSELLEVE"
     gene            482..817
                     /locus_tag="NOB31_001889"
     CDS             482..817
                     /locus_tag="NOB31_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974093.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDIHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEQ"
     gene            963..1532
                     /locus_tag="NOB31_001890"
     CDS             963..1532
                     /locus_tag="NOB31_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HCI0974094.1"
                     /translation="MNKQEAIKKLESIKVIGNDALAACYNESINAGITLMKKIDEPKK
                     LVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLYSVIIAGEYLVKEISCSNEVKLVSTAYLPQYLAH
                     HYQLTEKQIKAIDERYWPFAVPVEEVAEG"
     gene            1529..1702
                     /locus_tag="NOB31_001891"
     CDS             1529..1702
                     /locus_tag="NOB31_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974095.1"
                     /translation="MSRQIMLHIPDGTKAMTITIVAAQKDGGLALKTKSIDTKQILEG
                     RDVEIEIDEEEAE"
     gene            1699..2004
                     /locus_tag="NOB31_001892"
     CDS             1699..2004
                     /locus_tag="NOB31_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974096.1"
                     /translation="MNVQVYLKRDLARFPRSWDTNSHPSEAEEEGYLMSANMIEITRD
                     DADEFDKKRSWYSVPNPMYTAVIEDYHISDRFILIDLERPKKRIKQYRRCGFSTKKW"
     gene            2028..2225
                     /locus_tag="NOB31_001893"
     CDS             2028..2225
                     /locus_tag="NOB31_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HCI0974097.1"
                     /translation="MNNRHRRVAKLRNQELNVAKVKFEREYGVSAEETYKVASQCVAD
                     ASDAIRKFGISILDIKWEDTE"
     gene            2222..2428
                     /locus_tag="NOB31_001894"
     CDS             2222..2428
                     /locus_tag="NOB31_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974098.1"
                     /translation="MKIYVVKFGNQFYRSDERSIGANTLSIVDILQSARWFDNLEEAN
                     QVSRRLGGLTQVYELVTVDHEGVE"
     gene            2428..2724
                     /locus_tag="NOB31_001895"
     CDS             2428..2724
                     /locus_tag="NOB31_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974099.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTREKPKFKVGDMVRCEA
                     EGFIYPFRGYVEKVLSNSAIIRIENTMECDKWLAKSKENLAVARLVDMEVIESK"
     gene            2800..3213
                     /locus_tag="NOB31_001896"
     CDS             2800..3213
                     /locus_tag="NOB31_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HCI0974100.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            3897..4064
                     /locus_tag="NOB31_001897"
     CDS             3897..4064
                     /locus_tag="NOB31_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974101.1"
                     /translation="MYRPQYLEQKYEVITVQNGNGEIVRKYRRPIKSDTYKRKESNEV
                     IPLYGKRIAKH"
     gene            4090..4434
                     /locus_tag="NOB31_001898"
     CDS             4090..4434
                     /locus_tag="NOB31_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HCI0974102.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            4439..4720
                     /locus_tag="NOB31_001899"
     CDS             4439..4720
                     /locus_tag="NOB31_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974103.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVDIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNIFGYSIEEINYYIDFAEAFIPMVR"
     gene            4823..5137
                     /locus_tag="NOB31_001900"
     CDS             4823..5137
                     /locus_tag="NOB31_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HCI0974104.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            5115..6809
                     /locus_tag="NOB31_001901"
     CDS             5115..6809
                     /locus_tag="NOB31_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HCI0974105.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYNIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            6829..8007
                     /locus_tag="NOB31_001902"
     CDS             6829..8007
                     /locus_tag="NOB31_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCI0974106.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            7970..8656
                     /locus_tag="NOB31_001903"
     CDS             7970..8656
                     /locus_tag="NOB31_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HCI0974107.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            8656..9816
                     /locus_tag="NOB31_001904"
     CDS             8656..9816
                     /locus_tag="NOB31_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HCI0974108.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKEAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YRFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            9826..10701
                     /locus_tag="NOB31_001905"
     CDS             9826..10701
                     /locus_tag="NOB31_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974109.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNTGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            10698..11009
                     /locus_tag="NOB31_001906"
     CDS             10698..11009
                     /locus_tag="NOB31_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974110.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            10999..11352
                     /locus_tag="NOB31_001907"
     CDS             10999..11352
                     /locus_tag="NOB31_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HCI0974111.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            11342..11743
                     /locus_tag="NOB31_001908"
     CDS             11342..11743
                     /locus_tag="NOB31_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974112.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            11736..12140
                     /locus_tag="NOB31_001909"
     CDS             11736..12140
                     /locus_tag="NOB31_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974113.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            12152..12757
                     /locus_tag="NOB31_001910"
     CDS             12152..12757
                     /locus_tag="NOB31_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI0974114.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            12777..13139
                     /locus_tag="NOB31_001911"
     CDS             12777..13139
                     /locus_tag="NOB31_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974115.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            13341..16772
                     /locus_tag="NOB31_001912"
     CDS             13341..16772
                     /locus_tag="NOB31_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCI0974116.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFSDLWKKFTDWLGDTWESIKESASSVWDGVKET
                     WSGFVDWVQEIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPEFIMEGSF
                     NPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGPEAVLPLKRSVLQEIGDRILS
                     STSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            16823..17560
                     /locus_tag="NOB31_001913"
     CDS             16823..17560
                     /locus_tag="NOB31_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI0974117.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            17570..19861
                     /locus_tag="NOB31_001914"
     CDS             17570..19861
                     /locus_tag="NOB31_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCI0974118.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYDTAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYINDGDGNSLGIDGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDVDHFIIETSKPNVLVRWNLVAHRL
                     GYEDVRLKEDTAYDSTVLDQKRF"
     gene            19885..>21813
                     /locus_tag="NOB31_001915"
     CDS             19885..>21813
                     /locus_tag="NOB31_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974119.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDDQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFLAEIKGRMDSLNKQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLHVMYSNSIDFGGYDYSGNPNLMSKLKSSDFN
                     VGYHGSLTNVNGMLHFMSDGTGDIDMFTRINTPQLASGKTYTLSAKVRFDEGTTGAIN
                     KLRLVYRTSPGENILLEANNTTITIDDVGKEITIKGTANVNYQITNLDRFYISVSFSN
                     RDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWVGKTSLGKNIANKGTTFPIKSSAY
                     EIYKGNTEEELIIGQTYTITLKGTKPASQTFVAYNYWNVNFGDLKPVEGLTDVWSLTF
                     TPTKLEPGLPKDLRIFQSPKETAGACRIDWLKIEKGDTRTPNIEQYKYRGIGMRDSNN
                     PKDYVWDLEPSYVENNLATDIKVAEITGKANNYTDGKVSEINSQLTASINEVDTTAKD
                     AQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALN
                     GKSSGGNDSTILTIPEGYR"
BASE COUNT         7745 a         3234 c         4659 g         6175 t
ORIGIN      
        1 gatcggcaaa caaattggag caagaaactt catcaagatc gtttcaaatt tgtagagaag
       61 tataaagaga tattagacga atacatggag ggcagcaaat gataccgaga tttcgatcgt
      121 ggtacacacc atttaaaggt aaaacaattg gacaagaaat gaaatatggg caagcaggaa
      181 ggttgatcac tcatgctgaa atggctccag ataaatatgt gcttatgcaa tccacaggac
      241 tgaaagataa gaatggcgta gaaatatttg aaggggatgt agttctggtt aatgtaagta
      301 atggttttga tcatttagtt aatgaaaaaa cggttgtaca agaatccgag tttcattccg
      361 gattagtttg taaatcatta attagtggaa tggaatatag aatattcagc caccaaaaga
      421 tgggatacga atatgaagtc accggaaata tacacgagaa tagcgagtta ttggaggtag
      481 agtgattatc ttagctactg actacatcga ttctttaaaa gatgaaaatg ggaatgtccc
      541 agcattgcta aattgtggaa ttaaaagtaa gaatagaatc attttgttac ggatatcggc
      601 tgatttagca aaatatcttt atctgagcaa gacagcagta tattacactg cggctacacg
      661 ttatcagtac aagggaaaaa caatcagtca ggattattat gatcgtttaa tcagtcctga
      721 catacatgga aaatcaaaat cagcgatcaa gttatttggc gcaatagaga tatatgccga
      781 tgattttcca aatttatggt tgaaggagga acagtaatga aagactggtt agaagaagca
      841 agcgccttag ttggctgttt cataaactgt gcgtttatat ctgtaattat tgcactggtg
      901 ggatttgtat cattgaaagt gattatattg ctttggcagt taatttttta ggaggaacag
      961 cgatgaataa acaggaagca atcaaaaagt tagaaagtat taaagtgata ggaaatgatg
     1021 cactagctgc ttgctataac gagagtataa atgcaggtat tacgttaatg aaaaaaatag
     1081 acgaaccgaa gaagctagtt attccacaac tcgtggccgg ttggcttgag aaatctacgg
     1141 acccttttac gaaagctgaa aaaatagcgt atttaatcaa atctaaagat ggtgattcat
     1201 attatttctg tgattggttt gtacgagatg gcatagtgac gcaagaacaa ggagaagaat
     1261 tactcgcttg ggcaacgaga caatcatatg aaacactatt gagcttgtac aacggctacg
     1321 aggtcgagaa agagccgttg tacagtgtaa taattgctgg cgagtacctt gtcaaggaga
     1381 tcagttgcag taatgaagtt aaactagtat caacagctta cctgccacaa taccttgcac
     1441 accactacca actgaccgaa aaacagatca aagcaattga tgaaagatac tggccatttg
     1501 ctgtgccagt ggaagaggtg gcggaaggat gagtagacag ataatgctcc atataccaga
     1561 cggaacaaag gcaatgacga ttaccattgt tgctgcacaa aaagacggtg ggttggcgtt
     1621 gaaaacaaaa agcattgata ccaaacagat tttagaaggc agagatgtcg agatagagat
     1681 cgatgaggag gaagcggaat gaatgttcaa gtttatttaa aaagagattt ggccaggttt
     1741 cctcgaagct gggatacaaa ttcccaccca tccgaggcag aagaagaggg ctatctaatg
     1801 tctgctaaca tgatagaaat tacaagagat gatgcggatg agtttgataa aaaaagatca
     1861 tggtactcgg ttccgaatcc aatgtatacg gctgtaatag aagattatca tatatccgac
     1921 agatttattc tgattgatct agaaaggcct aagaaacgaa ttaaacagta tagacgttgt
     1981 ggattttcaa caaagaaatg gtgataacaa aacagaggtg aagaaaaatg aacaacagac
     2041 accgcagagt agcaaaacta agaaatcaag aactgaatgt agcgaaagta aagttcgaac
     2101 gggagtatgg tgtttctgca gaagaaacat ataaagtggc aagtcagtgt gttgctgatg
     2161 caagtgatgc tattcgtaag tttggaattt cgatactaga tattaaatgg gaggatacag
     2221 aatgaagatt tatgtagtaa agtttggaaa tcaattttac agaagcgatg aacgttctat
     2281 aggggctaac acattatcca ttgtagacat actccaaagc gcaagatggt ttgataatct
     2341 cgaagaagct aaccaagttt cacgacgact tggtggatta acgcaagtat atgaactggt
     2401 cactgtcgat catgaggggg tagagtaatg aaactaaaag acggatttta cgctagtagt
     2461 catggtatcg gcggtttgat gctagatatg ccgacaaaga accctaaaac acgtgagaaa
     2521 ccaaaattca aagtcggtga catggttcgc tgtgaagcag aaggatttat ctatccattt
     2581 cgtggatatg tagaaaaggt attgtcgaac tcagcaatca ttcgtattga aaacacgatg
     2641 gaatgtgaca agtggttagc gaaaagcaaa gagaatttag ctgtagcgag attagttgac
     2701 atggaagtaa tcgagagcaa ataaaaaagc cggatcgctc cgactaacat aataaaacag
     2761 acaagtttat tatatcacat aaaggagagg tttgacttga tgcaattgtt acgagaggta
     2821 gatttcaaac agacaagatg taatgcgaga gatgtgctga agaactttcg gcgtttggag
     2881 cggatggcag gtcgctcttt gatagatatt aagtctccaa ttattacgga tatgccgaag
     2941 gcgccgaagc acggcaataa ggcagaggac gcgatcattc agatgatgga tatagaagca
     3001 gagagagatg cgattttagc ggctttgatg gctcttagtc tgattagccg tcagatactc
     3061 tactacagct tttgtgtgcc agatagcttc tcaaactaca gaattagccg tgaagtgggt
     3121 tattcagaaa gaagtataca acggatgaag tcggaagctc taatagagtt tgcagaagca
     3181 tataaacacg gaagaataat tgcttataaa taatttggcg gttttttggc ggaatgatgg
     3241 cggtttttag ctatttacca gtgatattat ggtagtgtcg aaagattagt gataggtctg
     3301 agacaaaata ataataaaag gaacatcgtt ttattattgt ttcacaatta agcttcgata
     3361 gacagcaacg gaaatattaa gaataaggat gtgaatttca actccttcta aattgttctt
     3421 attatctatc atccgttgct gtctattgtt tttttaatta ttcacacgat aactaaaggt
     3481 gagtgaagag aaatgattcc attaataatt tcaatttttg cgctctgtct taatgtctat
     3541 atgattggat ttaaaaatgg gcaaaataaa aaatagtagc agccaagaat aattttatag
     3601 tgtcactgtg gcggaaaggg tagacgctta aaaataaggt caatacgtcg agggatagcc
     3661 ttaacgtttt atgatttgac catgcaatgt tcgattcatt gccagtgact ttggcaaccg
     3721 agggttggaa atgggcgctc aaagtacacg agcaaggcga ggtcgatagt aatcgatgga
     3781 atcggtgtag gttgcttgat agagctataa ctgcatctcg tttatgaggt gtagttttta
     3841 cagattagat cactctttga gtggtctttt tattttacac aaaggaggta acaagaatgt
     3901 atagaccaca atacttagaa cagaagtatg aagtaatcac tgtgcaaaac ggtaacggtg
     3961 agatagtacg aaagtataga agaccaataa agagcgatac atacaaacga aaggaaagca
     4021 atgaagttat tccattgtat ggcaaaagaa tagctaagca ttaaataaga ttgcgaaagg
     4081 agacggaata tgaccgagga attctataga tggctattac agttgataag agaagatcgt
     4141 ttagttaagt tctatcagtc tcctaaatgg cgcaggctta gagagaaagc gatgaaacga
     4201 gatcactatg aatgccaaga gtgtagaaga ctaggtaagt atcatagagt agaaaacgtt
     4261 catcatataa aggaagtcaa ggatagacct gacttagctt tagatttaga taatcttatt
     4321 tgtttatgtg ttgaacatca taatgaagtt catggcagat atcttacagc attagataaa
     4381 caagagaaga agatagaaag ctttgctaac ttcgatgcaa gtgaaaggtg gtaagtgcat
     4441 gatcatcaat gataatggca gagagtatga tacagaaaag attgaagagt attcatctta
     4501 tactcaggga ttaattaaac gtttgatata cgttcgctat gtagatatta gggatctgtt
     4561 atcagataac tgttgtagta aatacaaagt gaatcaagta agagaagcgt tgaataaaga
     4621 taataacgtt gaaagaataa aaaatatttt tggatatagc attgaagaga ttaattatta
     4681 cattgacttc gctgaagctt tcattccgat ggtgagataa ccccccctta aaataaatcg
     4741 caaatttttt gggggtgatg aaacggaggg ggctgtcagg aaaagagatt ttttcgaact
     4801 ttatcatgaa aggagggcta aaatgtttaa aaacgaattg tctcaaaatc gctacagaga
     4861 aaaattacgc cgctctttaa taagccaatt ggaaagtcag aaaacaaata ttgagccatt
     4921 cttagataat gttgatcgtt atatcagttt atgggaaacg gcgatatcac tggaagaaga
     4981 tatatccgag aacggcatta gactggagaa tggtaaaaag aatgaatcag tagcgttgct
     5041 tgtttctgtc aacaaacaaa tgggattgat gttggataaa cttgccatta ctcctgaatt
     5101 ggtaggtgaa gcaaatgaat caattcctga gttataagca tattgaaaat tggttcaaag
     5161 ctatagaaga aggcactatc aaggtatgca aagagcaatt attgctaaaa aattatctag
     5221 aagaaagagt ctttactaga gaagatattt acttcgataa gcagatggta gaggattcaa
     5281 tcaatatacc agcacaatac tttccattcg aattaattcc gtgggaaaaa tttctacaat
     5341 gttttattta tggtgttcga tggaaaaaag ataaaacact agtgttcaat agatatcttt
     5401 cattaatggg acgtggtaat ggtaaaactg gttttgcttc ttggaacaac ttctttctac
     5461 taaccgctaa acacggtatt aaaaattata atattgatat ctatgccaat aatgaaagcc
     5521 aagcaaagac tagttttgat gatgtattta aagtaattaa agatcatcct gatttagata
     5581 aaaaagtatt taaagctacg aaggaagtta ttcaaaatat cgctacaaac agcaaacttc
     5641 gttataacac ggcaaatgct agaacaaaag atgggaagcg accaggtgca aaccgctttg
     5701 atgaaattca cgaaaatgaa gattattcaa tgataaatgt ggctacttct ggtggtggta
     5761 aaattcgaga ttatagagaa ttttatgata caactaatgg tcatgttcgt ggtggtccgc
     5821 ttgatgacat tatagaagaa tcaaaaatga ttctttctgg agaacttgga attgacaagg
     5881 atggagcaga attttctagt ttgtttccat ttatttgtcg cttggataac gataatgaag
     5941 ttgatgatcc cgacatgtgg gaaaaagctt gtccaactat taattacaat gcagatttaa
     6001 aacggaaaat gtttcaagaa tactctcaaa tgcaacgtaa tgctggttta agacttacgt
     6061 tcatgaccaa acgaatgaac agacctatgg aagatacacg atttgctgtt gcttcatatg
     6121 atgatgttct gcatacgaaa gaaaaagaat ttcctgaaaa aatggatgaa gtgataggaa
     6181 cagtcgattt tgctgataga cgagattttg ccagcgttgg gttgctagga aaatacgata
     6241 aagatgttta ttttacacaa catactttta tccacgaatc agcccttcga ttacaaaaca
     6301 tcaaacgaga ggttatagat atttctatag atcaaggaaa atcacagatc gttcatggaa
     6361 aaaatataga agctgattat attgtaggtt ggtttcttga aatgagtaat aaatattata
     6421 ttaaaaaaat cgctatggat atgtaccgtg caaaaatatt gaagcccgct ttagaagaag
     6481 caggttttac tgtggaaatt gttcgaagcg gatctgttac acatggtatg ttaaaagatc
     6541 tggttgatga cctttttatt aatcaacgtt tattttttgg tgacgatgcg attatgcgtt
     6601 ggtattgcat gaatgtatat gaagagcata tttctaatgg aaatatacgc tatgaaaaaa
     6661 tagaacctga aactagaaaa acggatggct ttttttcatt ccttcatggt ttgaattttt
     6721 tagatgatat ttatgattct gctcctgtaa cagtcacaaa tagctcagta gaaaatacag
     6781 gaactggatt tactcctcta gtattctaac ttgaaaggag gtgagaaagt ggggattttt
     6841 caaaaggcgg taggatactt cacaaaaaaa gcaacggttc ctttagaaga atacttttgt
     6901 aaattgcaag ttgattttgt gtatcgaaaa tttgcgattg aaacttgtat tgatttgatt
     6961 gcaaatgcga tgagtaaagc ggaattcaag tcatatgaag atggaaaaaa taaaaagaat
     7021 gatctttact ataggctgaa tgtagctcct aataagaaaa ataatgcaac agaatttaga
     7081 aaaaaactga tcaggagatt aatattctac aatgaagtat tgatcgtttc tccgtctaat
     7141 aattctagcg aaatatttat tgcggatagt tgggatgtca cagaatatgc attgaaagat
     7201 gatgtgtttt ctcaagtgca aattaacaac atagtccttg atagagaatt tctagaaagt
     7261 gatgttatct atataaaata cgcagatcaa caaattaggc aactagtcga tgcgtattat
     7321 caagcgtatg ggaaactcat ttctagtgcc atgaatgttt acaagcgctc taacgctcgt
     7381 agatacgtac tgaaagggaa tttattccga ccgcaagaca atacaacaca agatcaaatc
     7441 aataaaatga tgacatcaca atttaaggct tttatggaag ctgataatgc aggtgcggta
     7501 tttcaattac aaaatgagta cacattagaa gatttcagcg gaaacttcca aagcaattca
     7561 agagatataa aaaacttaat agacgacatc tttgagatga cagcagcagc gtttcacgtt
     7621 ccgaaaaacc tactaaaggg agacatgagt gggttatcgg atcaagtgga cgctttttta
     7681 atgttcgaaa tcataccgat tgctgaactt attcaggatg cgtttaacgc tagtctctat
     7741 gaagtagaag aatacttgtc agggaatttt gtacgtgtgg atacaactat gatcaagatt
     7801 actagcttca aagatttggt tgacgctatt gatgtaggca ttagaaatgg agtatttaca
     7861 atcaacgaag gaagagaacg cgttggaaat gatcgctctg ataaggcgat ggcagatgaa
     7921 atatttataa ctaaaaacaa tcaacaagta tcgaaaggag gtgaggcgaa tgacgacaat
     7981 gaaaacattt ctagcagtaa agaatgaagg cgcagtaccg caaattttta ttcagggatt
     8041 tattggttct agttggttct ttgaagggaa tactgacaag ggaatcaaaa atattttgga
     8101 tagtctaggt gatcaagaag aaattgaagt agtaattaat tcaaacggtg gagacgtatt
     8161 tcaagggatt gctattggga acttacttaa gtcaaataaa gcaaaagtta acgttgtgat
     8221 taacggctta gccgctagtg ctgcttcaat tatcgcaatg gctggcgata ctataaaaat
     8281 ctacaacaat gcacaattga tgattcaccg cgcttccaca tacggagaag gaaatgtcga
     8341 tgacttccgt acgattgctg accaactgga atcaattgat aaatcggtaa aggcttcata
     8401 taaaacacga ttcaatggca cagatgaagc attgcaagaa cttcttgaaa aagaatcgtt
     8461 tatggatgca gaaacagctt tgagttatgg attggtcgat gaaattatcg atgcagaaaa
     8521 tagctcaggt actgaagcta aaaaagaaca aagcgttgaa gaaattttga atgacgttaa
     8581 agaaaaaaga gcagaaaaaa ttgctgcatt tacagcagca ttaaataaaa catttggaca
     8641 aggagatgta aaataatgac agttaaaaat ttaaaaggtg taacagctgc aagcgaccaa
     8701 ttgatgaaag cttttaaaga tggtaacgaa gaatctttta gcgcagctat ggtaagctta
     8761 tctaaggaaa ttcaggataa aattttagaa gaagcaacag caaaaaatca agatcaatta
     8821 gtattaatga accgtggtca gcgtgtatta actacacaag aaacaaaatt ctataacgaa
     8881 gtagtgaaaa acgaaggttt tgcaggggtc gaagaattag tgccagctac tgtatttgaa
     8941 cgtgtatttg aagatttaga acaatctcat ccactattgc aaaaaattac ttttgttaac
     9001 acaactggtg taacagaatg gattgtgtca cgtggagtca atccagcatg gtggggtaaa
     9061 ctttgcgaag ctgttaaaaa agttttagat aatggctttg atgtaattaa catgaagcag
     9121 ttcaagctat caggttatat tcctgtatgt aaggcaatgc ttgatttagg tccagtatgg
     9181 ttagatcgtt atgtccgtac tgttttagta gaatcattga gaattgcatt agaacaagca
     9241 attgttgatg gtactggtaa agatatgcca gtcggaatga tgcgtgacat gagcaaacaa
     9301 actagcggag aatatgctga aaaagaagca gaacctatta cagctttaga tgctgtaact
     9361 atgggcggtt tgatggcgcg actatcaaaa ttcaatatcg aaggtgtgaa tgatccgatt
     9421 tatcgtaatg tgaatccttc tgatgtggtc ctaattgtga atccaactga ttactggtct
     9481 aaagtattcc cagctaagac tgtactaact gctaatggag aatacgtaca agtattgcca
     9541 gtaccagttt cagatttgca gtcaacggct gtgccagaag gaaaagcagt tattggggta
     9601 gcctcagatt acttcatggg tgtaggatct acactaaaaa ttgaagcttc agatgaatac
     9661 cgttttgttg aagacgaacg catttatcta gctaaacaat atgcaaacgg tcaacctaaa
     9721 cgtaacgata gtttcattgt attagatatt agcgctttgg gaactactac tacaactaca
     9781 aaaccaacaa ccacaacaac tacaacacaa gcgtaggtga tcagaatgaa gtatattctt
     9841 tgtcagccgg caatcaatcg gtttaaatgg gagcttgaag tttgtttaac taatctgaag
     9901 aaactaggaa tcaaagatat cgtattgctt ttcagcagac acgatgatca gattcctatt
     9961 ttttttgaga aggaatatgg tgttgaagtt catgtgtacg atgatctgcg ggacgacaaa
    10021 gagtatattc cttcgattaa accatattta tggtggaaat atttagaaga agatcattcg
    10081 cgtgaggacg accgatattt ctatatcgat tcggatgtca ttttcaataa aagaattaat
    10141 ttgcgcaaat tgccttctaa agatgatgtt tggtattgta gcgactgctg tagttatcta
    10201 agtcttgatt atattagaag ctgtgaaaac ggagaaaata ttctaaaaga tatggcaaac
    10261 attgtaaatg ttacagtaga atctttggaa actataaaca ctaattcagg aggcgcacag
    10321 tgggttatta accgtcctaa agcgaattat tggaaaaagg tttatctgga ttctaatcgg
    10381 ctatatcgct accttagagg gcaaaaaaca aatatacaaa tctggacagc cgagatgtgg
    10441 gcacagcttt ggaacatgat gtatttcaat attggtccta aagttcacga ggaattagac
    10501 ttttgttttg ctactgatcc aatagaaaaa gttaaagaag taaaaatctt acacaatact
    10561 ggagtaacaa caaacgatga agatttattt ttcaaaggga gatacgtgac ttctacgcct
    10621 tttgatgaag atttatcatt tgtaaacaag aaaaaatgct cttacgcata tgttaaagca
    10681 attaaggcgg tggttagatg acgcctgaac aagtgactga agaattgcta atagctgtga
    10741 aggataatat ttacgttacc tggaacgaag aagatgagtc aattaaaaag atgatagcta
    10801 aaaatgctgt ttatcttcaa agtaaagtga gtacaacact ttctttttct cctgaaagct
    10861 tagaatacgg attgctaatc gaaagatgta gatacgactg gaatcgtgct ttagatgagt
    10921 ttgaacaaaa tttcgctagt gagttattag gtttcattca acattatgcg ctacaagaat
    10981 atattgcagg tgatgtgaat ggcgaataat cgtagactcg aagaaacatt caacgatggt
    11041 tggttaaaga ttttgacgca aactaccaaa agaaatgaac taggaaaaaa gattggtgta
    11101 gaagatacag aaatcacttc tttaaaattt agaaatcttt ccatgagaga tagtgatata
    11161 acagctatgg atgcgatggg atcgaaatta actaagaaag taaagactcc atttcatcca
    11221 atcgccaaga aatttaataa agatcaatat tttatcgtaa tcgatagtat gcgttacaac
    11281 gttatctatg ccgattacga taatttttat atctattttt atcttgaaag tgtgggtgaa
    11341 tatggtgatt gataattcta aagaaaaaga acgtttaaat aagcaaattt ctgctatcaa
    11401 aacttcctta gaagagcatt ttggcctcaa actctttcaa gactccgtag gcgaggatga
    11461 gctacctgat gattttaatt acttcattct cgaaacagga gaaatagaaa tgatcactga
    11521 gccaaaatat agcgtgggtc aaaatctata tctaactttc tattcagaaa atagagaaga
    11581 tttaacagga gattcactag atattatttc attgattcaa aatcgttcga ttcgttttca
    11641 gagaatggat cccaatcatt taaaactaga gaaccaagat cgctatatcg atcaattggt
    11701 atttacgttt agacgattat tgaagagtga ttgtcatggc taaaaatagt tgggagctaa
    11761 aaataaatgg acatgatgaa cttcttgtgc ggatggaacg ctattcaagc gagagcgaac
    11821 gactgattaa cgaagcattg aaatcaaaag gttcggctat tgcagtggat aggattacag
    11881 aaaaaattcc tgtttctgaa gcagatttaa gaagagggca ccaacacgca aaaaatagtc
    11941 gtccacttaa gactcaatac attaatttgg gtttcatcat tagacctaca agaaaatttg
    12001 agtatttaaa atatcctgat ttggggatag gtacttctaa aagaaatcag ccggacgaat
    12061 ttatgagaag aggattaggt cttgcacttg atccaattac agaacttctg attcgtcaat
    12121 tcgataaatt aaataaatag gaggaacaac aatggctaaa acaacaacag taacaacttt
    12181 tgacaatata agtattaaaa gaatttcttt taattttaag aatgcaacaa atgcaatttc
    12241 aactgattgt aatggacaat tagatggcga aacagaaatg cagagaattg taaaaaaatg
    12301 cggttcaaca gaagtaaaat cgaaatctaa accaatcaat atgacggtaa caattactgc
    12361 acatgtaccg atggaagttt atcgacgctt caatgggttg aaacaagatg aacgtattaa
    12421 atcgggaatt tactcttatg gtcctgattc cgtaggggaa gatttctcac ttgctgcaga
    12481 gatcgtggat gacttcgaag aaaatagaaa gttagttggt atgttagcat gcacttcgaa
    12541 tacaggatta acattctcta ttgaaaatgg tgcggatgaa gtagctgcgt tagaactaga
    12601 aacaaaagtt atgcaagatg aatttggtaa attttatcat gaagcaattg ttgcagaact
    12661 tgaagaagac ttaacagatc aatggatgac gaatctatct gctgatgtga ttaaaaaaac
    12721 ttcagttgtg acaactacgg ccactcaatc acagtaaaaa aaacggaggt agcgaaatga
    12781 acgaagatta ctcaaaaatt gaactaaacg atggaacaat tttgaattta gaacctaaac
    12841 tgaatatcaa gaaattattg atgatcaata gagattttaa cacagacgag tttgcaaaaa
    12901 tgactgtggg aaaaggatcc atggatattt ctgttattca aggtgcaaag gctgtgtata
    12961 ttgcttaccg ccaagcgaac atgactgatt atatttcatt cgatgaattt atcgataaat
    13021 gggattttga tatggctact gccagctata tttatcaatt gatgatgttc aaacaagcac
    13081 gcgatgctta tcaaaaagaa tttgaaaaag caaataagga aaaaaagctt caaaagtaaa
    13141 aattccaaag ctcttagttg aaacgtgggt cgatgtctat tcgatgttga ccgacgtttt
    13201 ttctatgcct tcagatttgg ttttaagcga tatctgttta gatgacattt tgcaaatggc
    13261 ttacaacaag agtgcttatg aaggatggaa aaactatgca ataaaccaat cccagaaaaa
    13321 ctaaagaaag gaggtaaaaa atggctaaaa agagaacaga agcagaagta actttcatag
    13381 ctaacgatga cggattgaaa tctacgttaa aagaaatcag tgctgaatta actaaaaata
    13441 gagcagaatt aaaactagaa caagctcaat tacaacagac tggttctgaa tcagacaagt
    13501 taggaagtaa attatcttct ttagaaaagc agtatgaatt acaaagtcaa aaagttgaag
    13561 taactagcca acgtttagcc aatgcgaaaa aatattatgg agaaaattcc accgaagttc
    13621 agaaacttga aagagaactg attaatcaac aaacagcgca acaacgtttg tcaaacgaaa
    13681 ttgataaaac gagtaatgca ctagctcaag caaaaggcga aatacagacg tacgagtcta
    13741 caatgcaaca gttggatagc gaacaaaaaa atgttcaagc tagtgcttct ctgattgaat
    13801 ccgaatacaa aaaatggcaa gcaactgctg gtcaatcagc ttctgaagcc gagaaattag
    13861 cgaaagccca agaatatgtt tctcaacaat ctgaaaatgc ggagaaaacg atagatatcc
    13921 taagacgaca gttagaagct acacagtctg aatttggcgc tacatccaca gaagcaatgc
    13981 agatggaagc gaagcttaat gatgctgaac gtgaatttga agagttagga caagctgcta
    14041 aaaatgtaga tacaactaac ttggacgata tcggaagcaa aatagatatg aataatttaa
    14101 tggaagcttc tgacgtttta agcgacattg gcgataagct tacagaatta gggaaacaag
    14161 cagtggactc tgctaacagt gtaggtagtt cccagagtaa gatacaagct aattttggtt
    14221 tgtctaaaca agaggctgaa gaattaacga atgtagccag agacatttat tataaaggtt
    14281 ttggagaatc gttagatcag tccacagatg cattgatttt ggtaaagcgt aatttaggag
    14341 atttaaataa tcaagattta caaaatatca cggaacaagc tatggtccta gaaaacacca
    14401 tgggcgctga tatggatgaa acgttacgtg gtgtaaatgg cttaatggtc aatttcggct
    14461 tgagtgctca agatgcaatg gatttaatgg tttcgggtac tcaaaacggt ttagataaaa
    14521 cgcacgaatt aggcgacaat atggcagaat atagccaatt atggagtcaa atgggatatt
    14581 cagctgatga aacgttcgga atgcttcaaa atggtttaga tgcgggtgct tataaccttg
    14641 ataaagtcaa tgacttagtt aaggaaatgg gaatatcgtt aacagatggt cgatttgagc
    14701 aaaacatgga tatgtttagt gaaagtacta gaaaagcttt tgaagagtgg aaaaatggcg
    14761 gaggaacaca aaaagacgtt attaattcca tgattcaaga ttttagcaat atggatggtc
    14821 aatacgacca attaaataaa gcttcgacaa tttggtctgc gcttggcgaa gataatgcga
    14881 tgaaagttgt ccaatcttta actgatgtta accatacatt tgatgatgtt agtggatctg
    14941 cacaaaaaat gaatgaagat tctactactc cgttacaaga attaaacgga aaaatagctg
    15001 aattaaagga ttcattagct cctataggca acacaatcat agatgcactc gaaccagtaa
    15061 ttgattttct aggaaagatg gctgatgcgt ttaataatct tccacaacca gtacaggatt
    15121 atgccgtagc gattggcgga ttgactgctg catttacttt attaatgcca ataatagttg
    15181 gcttcatggc tctaggtggt cctactacat taataatagg agcagttatt actgctattg
    15241 ctggagttat agcaattata aaaaactggg gcgcaatcac tgactggttt agtgatttat
    15301 ggaaaaaatt taccgattgg ttaggtgata cctgggaaag tataaaagaa agtgcctcat
    15361 cagtttggga tggagtcaaa gaaacctggt ctggatttgt agattgggtt caagaaattt
    15421 ggcaaggagt ttctgattgg tttggagagt tatggagcgg attagttgaa ggagcttcca
    15481 acatctggca aggagtccaa gagacttggc aagcattcgt tgattgggtt tcaaatattt
    15541 ggaacggagt caaagaagta tggtcgatta tttgggcaga cattgtagga attgttcaaa
    15601 taccatggac attaataacg tcattgattc aagctggtat taatattatc gtgggtatct
    15661 ttgatgtagc tggacagtta ttaggcgcag cttggcaagc tgtttggaca cctatttctg
    15721 atttccttaa aaatacttgg gatactatga cacaatggat aagcatcgct tggaatggaa
    15781 ttgtaactac attccatact atatttgatc cagtagtggc atggtggaat ggtatatgga
    15841 catctattag tactacggct tcaaatattt ggaattcaat tagtgcaaca gcttctagta
    15901 tttggaacag tatcaagaat acaatcacta gcttggtaca agcagctgct acagtaattc
    15961 aaaatatttg gtcaactgta tctagttggt taggtggaat ttggaattca atcagctcta
    16021 cagcatcaaa tatctggaat agtgtgacta gtagtataag caatgctata aacgcagcta
    16081 aaagtgccat tcaaagtgtt tggaatagta tatcttcgtg gatcagcgga atttggaacg
    16141 gtatcaaaaa tactgctttg aatctttgga atggaattac aagcactatt agctctaaag
    16201 taaacgatgg aaaaaatgca atttcaagcg gttggtccaa tctaacaggt attgtttccg
    16261 acatattcaa taatgttaaa agtacaattg ctaacatatg ggaaggcatc aaaaagactg
    16321 ttagcgctcc aattgattgg attagagaca aaatcagtgg catttttgat aatttgaata
    16381 tttctatacc acatattccg ttaccggaat ttatcatgga aggcagcttt aacccgctaa
    16441 aaggtcaaat cccccatttg cgtgtaaaat ggcatgctaa aggaggtatc tttactaaac
    16501 caactttact aggtggaatg aacggtgtcg gtgaagcagg acctgaagca gttttacctt
    16561 tgaaaagatc tgttttgcaa gaaattggtg atcgtatctt gagtagcaca tcagtttcat
    16621 ctagggcaca aacgattcaa cctgtgaata actacgaatt caatttcaca attgatggta
    16681 acgcagatga ggttactatg aagcaaacaa ctcaacaaat cattgatagc attacaaaaa
    16741 ttcaaaatga taatgcttcg gcatggcgtt aaacaggaga gtatttctcc tgttttttta
    16801 gtattaaaaa ggatgtgaaa aaatgactga ttgtatacat tctataatcg atggatttcc
    16861 tgattatttg cataaattgg ctttagctga aagaccaacc ataccttctc caaaaagaca
    16921 gagagttgaa acttctgttt taggtaggtt aggtggctta gtacaagatt actcgtttga
    16981 agatatgtcg tttacattgc actataacta tttagaggat gtggaagacc atcaagcgtt
    17041 caagcaatcg ttttatatca tgcgtcattg gttaaactat gcaaagaaat tagaattctc
    17101 tgacgatccc aacgtctatt acgttatcca gactatcgat attggggatg cagaaaacga
    17161 tattgttgaa tggggagagt tcgatgtaaa tattactgcg aaaccattcg caagagttca
    17221 agaagatgta cctataaccg tagataaacc acagtcattt aacttgctga ataatagttt
    17281 agaagaaagt tttccaaaga ttatcatcac tccttcagct acttcatgcc agttcatctt
    17341 aaatgattat gtgtttagtt tcgaaggctt agtagcagga actgatgtag tcattgatag
    17401 tgatttgatg ctttgctacg aagagcaatc ggacggagat attttagatc ggtccaacaa
    17461 aatgaagacc atgcaatatc caacgttgca agtggatatt aatcatttta attgtactgg
    17521 tttgagcaaa atacaaattt atcgtaacgg gttaaggtag gtgaaataga tgatcgataa
    17581 tttaataact atttacgata aaaatgacgc gaataattta gctgaacatt tatatgatac
    17641 gcaaggttta ggcgctttgt cagactggtt aacagctact gttagcaata aactaaacgg
    17701 agccgagata tttcagggta cttattcaat aaacggaact aatgcagatt tgattgtaga
    17761 aggacgtatt attcagtgtt atgtagatga aaatcgagca aaacagcgtc tacggattta
    17821 ttatgcaaaa acttctgtaa taggcaatac gatagaagta aaagctgaac ctattttcaa
    17881 tgatataaga aaatcggtgt tgaataaata tgacagcgga acagaaaaga tcactgctac
    17941 tcaggcatgg caaaacgcaa aagttttagc gaaaccagct atcccttcgc agttttcttt
    18001 ctcgtcatta gtagatacgc ttgctaatgt gaagatagaa aaggcgaatt ttttagaatt
    18061 ctttggtgga aaagagggat ctattctaga tcgatttcat ggtgagtttc taaaagataa
    18121 taacacatta cgtcatgaaa aaagtctagg tacggatcat aaaatcaaag cgatttatac
    18181 taaaaactta actggtcttg acttagagat tgatgctcaa agtgttttag ttggagttta
    18241 tccattcatt agcagctctt cagaaggaga agacgagatc actctaccag aagaagttat
    18301 tttcacggat tacgtggatg attatcctgc tggatatgtt tcttttgttg attttaaaga
    18361 caaagcgact gatgtagcca cattaaggga agctgctaaa gactggttga aaacaaacat
    18421 agataaacaa aaaccacaag tgagtggttc gattgaatta gtaccattga ggcatcaaag
    18481 aggctatgaa aaatttgttg atctagaaaa agtttcgatg ggtgacggag tagatgtgta
    18541 tcatccacag ttaaaagtga atatgtcagc gagaattgtg gaatatacgt ttaatgttct
    18601 aaccaattca tacgataaat tagttgtagg aaacgtcaaa acaaacttct tagaaaacac
    18661 agagaataat gtcagcaatt tgattaatga tgccattgat caattgaaaa atggtggcga
    18721 aatcagtgat ttaatcaatg atattgtaga tcatcaaact gatatgatta ctggtcaaaa
    18781 tggtggttac gttttattag atcctaaaga agcccctagt cgtattttga ttatggacac
    18841 accagataag aatactgcac ggaacgtttt gcaaatcaac aacgctggta ttggtttctc
    18901 taaaactggc attaatggaa cgtatgacac cgcatggacg ttagatggcg gattcaatgc
    18961 ctcgtttatt acagctggtg agatagtagg gattactatt agaggtacta cattaattag
    19021 tgatggcact gattatagaa caagtatagc taatggcaaa atgacttggt actcaaaaaa
    19081 agttaacaaa gatattatgg agctagaagc acgtgattat gtaagtgctg atgccggcat
    19141 tgtatcatac accatgaaaa ctggtggtgg tttcatgatt agaaatccac agggtaactt
    19201 ggtttttagt acgtgggata atggtaataa cagaccgttt ttatcttttg gtgcgccaaa
    19261 tttcagatac agtaatgcta gttatataaa tgatggtgac ggtaattctt taggtattga
    19321 tggtagtgca ggtaattcat gggaatttaa agtagctggt aggactatga aatttactag
    19381 tgacggtatg ctaacgttgc caggttgttt ttttggttca tgggaagatg ggaaacttgc
    19441 tagatttgaa caatcaacgg tacaagtata taaagatttt actgttagag gtactaaaaa
    19501 ctcaaccgta ccaacagaac attatggaca acgactattg aacgcttatg aaactccaga
    19561 atattatttc gctgattatg gggaagccgt tacaggtgat gatggtaaag ttcgtgttga
    19621 tattgacccc atgtttgctg agacagtaaa tctaagtcgg tatatgacac atgtgacacc
    19681 tacagaacta gttttgtgtg ctgttactca tgaagatgtt gaccatttca tcattgaaac
    19741 tagtaagcca aacgtattgg ttagatggaa tttagtggca catcgactag ggtatgaaga
    19801 tgttagatta aaagaggata cagcatatga tagcacagtg cttgaccaaa aacgttttta
    19861 aaacgaagac aaggaggtat ataaatggct agcagtttat ataatttggc tttagatttc
    19921 agcaaagaat taaactacac caaagctatt atggctcgtc aaggtgataa agggatcacg
    19981 gtgactgtta aaccgttttt aaatggcttg cagatggata cgagcggcgg aacatttact
    20041 ttaaaaggaa ctacgccatc taaccgttac gtagatagtg tcgctactag tgtaactagt
    20101 gaagaagtca cattttctct tgatggcaca tttatgagtg aagcagggta ttataaacac
    20161 tgctatgtag aatatagaaa agacgatcaa attttaacga cgcaagatat catttttttc
    20221 tcactaggag tgtctgacat ttcgcaaggc caagccgatg aatatgtttc gcaattagaa
    20281 gaattgattc gaaagtataa cgaaactttt gatgcttttc tggctgaaat taaaggtaga
    20341 atggatagct taaataaaca gattactgat ttaactggtc aagctaaaac actacaagac
    20401 aagttagatg ctctgaaaga agaaatttct aaattaggta acttacatgt gatgtactcc
    20461 aacagcatcg acttcggggg ctatgattat agtgggaatc cgaatttaat gtccaaacta
    20521 aaatcgagcg attttaacgt tggttaccac gggtcactaa ctaatgttaa cggaatgtta
    20581 cattttatgt ctgatggtac aggggacatt gatatgttta cgcgtattaa tacacctcag
    20641 cttgctagtg gcaaaacata tactctgagt gcaaaagttc gatttgatga aggaactaca
    20701 ggagctatta ataaattacg tttggtatat cgtacatcac caggagaaaa tatattattg
    20761 gaagcaaata atacaactat tacaatagat gatgtaggga aagaaataac aatcaaaggc
    20821 acagctaacg ttaattatca aatcacaaat ttagatcgtt tttatattag tgttagtttt
    20881 tctaacaggg ataaaataaa tggtggattt aaattgtacg acatcaaaat cgaagaaggc
    20941 tcaacagcca ctccgtatca gccaaactta ctagatgacc cttactgggt aggtaaaaca
    21001 tcgttgggta agaatattgc aaataaaggt acgacgttcc caattaaatc tagcgcgtac
    21061 gaaatatata aaggtaacac ggaagaagag cttataatag gtcaaacgta tactatcacg
    21121 cttaaaggaa caaaacccgc aagtcaaacc tttgtagcat ataattattg gaacgttaat
    21181 tttggagatc taaaaccagt tgagggattg acagacgtat ggtctctaac attcacacca
    21241 acgaaacttg aaccgggttt gcctaaagac cttcgcattt ttcagtcgcc taaagaaacg
    21301 gccggcgcat gccgaattga ctggctcaag atcgaaaaag gcgacacacg aaccccgaat
    21361 attgagcaat ataaataccg aggaatcggc atgcgagact caaacaatcc aaaagattat
    21421 gtatgggatc tagaacctag ctatgttgag aataacctag ctacagatat caaggttgct
    21481 gaaatcacag gtaaagcaaa caattatacc gatgggaaag tatcggagat taattcgcag
    21541 ttgactgctt caattaatga agtagacacc acagctaagg atgctcaaac aaaagcgaat
    21601 gctaatgcga ctgctataga tgaattagac aataagatcg atgaacgcat taatgataca
    21661 gctactacca cattaacagt tacaaacggg aataccggat cagcaaagct ttatcgtgaa
    21721 ggaaaaacag tttctatata ttttgtggct ttaaacggaa aaagcagtgg tggaaatgat
    21781 tcaacgatac taacaattcc agaaggctat cgg
//
LOCUS       DAIGSZ010000048        21448 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.048, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000048 DAIGSZ010000000
VERSION     DAIGSZ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.048"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            129..830
                     /locus_tag="NOB31_001916"
     CDS             129..830
                     /locus_tag="NOB31_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI0974120.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1439..2455)
                     /gene="tsaD"
                     /locus_tag="NOB31_001917"
     CDS             complement(1439..2455)
                     /gene="tsaD"
                     /locus_tag="NOB31_001917"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HCI0974121.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2452..2916)
                     /gene="rimI"
                     /locus_tag="NOB31_001918"
     CDS             complement(2452..2916)
                     /gene="rimI"
                     /locus_tag="NOB31_001918"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCI0974122.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2923..3465)
                     /gene="rimI"
                     /locus_tag="NOB31_001919"
     CDS             complement(2923..3465)
                     /gene="rimI"
                     /locus_tag="NOB31_001919"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCI0974123.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3449..4171)
                     /gene="tsaB"
                     /locus_tag="NOB31_001920"
     CDS             complement(3449..4171)
                     /gene="tsaB"
                     /locus_tag="NOB31_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HCI0974124.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4362..5342)
                     /locus_tag="NOB31_001921"
     CDS             complement(4362..5342)
                     /locus_tag="NOB31_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0974125.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5366..6850)
                     /gene="galT"
                     /locus_tag="NOB31_001922"
     CDS             complement(5366..6850)
                     /gene="galT"
                     /locus_tag="NOB31_001922"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HCI0974126.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6862..7851)
                     /gene="galE"
                     /locus_tag="NOB31_001923"
     CDS             complement(6862..7851)
                     /gene="galE"
                     /locus_tag="NOB31_001923"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HCI0974127.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            8099..8266
                     /locus_tag="NOB31_001924"
     CDS             8099..8266
                     /locus_tag="NOB31_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HCI0974128.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(8328..10139)
                     /locus_tag="NOB31_001925"
     CDS             complement(8328..10139)
                     /locus_tag="NOB31_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HCI0974129.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(10136..10501)
                     /locus_tag="NOB31_001926"
     CDS             complement(10136..10501)
                     /locus_tag="NOB31_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HCI0974130.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(10664..11059)
                     /locus_tag="NOB31_001927"
     CDS             complement(10664..11059)
                     /locus_tag="NOB31_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCI0974131.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(11077..12039)
                     /locus_tag="NOB31_001928"
     CDS             complement(11077..12039)
                     /locus_tag="NOB31_001928"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HCI0974132.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(12039..12251)
                     /locus_tag="NOB31_001929"
     CDS             complement(12039..12251)
                     /locus_tag="NOB31_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HCI0974133.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(12272..12970)
                     /locus_tag="NOB31_001930"
     CDS             complement(12272..12970)
                     /locus_tag="NOB31_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HCI0974134.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(12990..13532)
                     /locus_tag="NOB31_001931"
     CDS             complement(12990..13532)
                     /locus_tag="NOB31_001931"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HCI0974135.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(13664..14668)
                     /locus_tag="NOB31_001932"
     CDS             complement(13664..14668)
                     /locus_tag="NOB31_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCI0974136.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(14665..15654)
                     /locus_tag="NOB31_001933"
     CDS             complement(14665..15654)
                     /locus_tag="NOB31_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCI0974137.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(15651..16457)
                     /locus_tag="NOB31_001934"
     CDS             complement(15651..16457)
                     /locus_tag="NOB31_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974138.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            16623..17579
                     /locus_tag="NOB31_001935"
     CDS             16623..17579
                     /locus_tag="NOB31_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0974139.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(17656..18174)
                     /locus_tag="NOB31_001936"
     CDS             complement(17656..18174)
                     /locus_tag="NOB31_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI0974140.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(18262..18411)
                     /gene="rpmG"
                     /locus_tag="NOB31_001937"
     CDS             complement(18262..18411)
                     /gene="rpmG"
                     /locus_tag="NOB31_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI0974141.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            18639..19085
                     /locus_tag="NOB31_001938"
     CDS             18639..19085
                     /locus_tag="NOB31_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HCI0974142.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(19280..21175)
                     /gene="asnB"
                     /locus_tag="NOB31_001939"
     CDS             complement(19280..21175)
                     /gene="asnB"
                     /locus_tag="NOB31_001939"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HCI0974143.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         6454 a         4550 c         3699 g         6745 t
ORIGIN      
        1 tttacataat aacaaattat atttgtaaag tattaaaact tgtttctaat gttggtatgt
       61 taaaacttta caaattcttt aaaaaaagtg acaataaata tagtgaacaa taaggagagg
      121 actttttaat gcgtgttaat aaaatcgatt ttcacttttc aaaactcaga tatcaacctg
      181 attttgaaca tttctcggat gaagagttcc aacagatcaa ggaacatact gttcttcgtt
      241 cttataaaaa aggacagatc cttttcgacg atggtgatcc cagacaacgg ttgtatatct
      301 tgaccaaagg actcgttcgt ttagaacgtt atgatgaaag tgcaacttat tactactatg
      361 actatgtgaa tacaaataac ctttttccta tgtcaggaat gtttggagaa gagacctaca
      421 cttatacagc tcaagcgatg actgatattg aaacattcta ccttcctgtt tcctactatg
      481 aaaaattagc acgaaaaaat cccgaacagt tgatctatat gatacaaaaa atttctaaag
      541 tagttgaaat acatgaattg cgtatccaaa tcggattgac ctctagcgcc tttgaccggg
      601 taaaacaaaa tttattcatt ttgaaagaag aattgggcgt accaacaaaa gatggtcata
      661 tcaccattcc ttatccgatc accttaaaag aattagcagt gaatagcggc acgacacgtg
      721 aaactgctgg acaagtaatc aaacaactac gtgattccgg gctgttagat tatgacaaaa
      781 agcgttttac tttctgtaag acagctacta ctccagctat gagagaataa cgcgaacaaa
      841 aataagcagt gaccctgata aatatcaggg tcactgctta ttttcctccc taaaacttct
      901 gaaagatccg gcagttttag atcactggac aagactcaaa gattttctat gtgtgtttca
      961 gttatgtaat attcactgtt tgcaaaaaat actgttagat taactagatg aagcgtcttg
     1021 tcctcatccg atctagatta ttcgatattc ctcgacaata aacgattact cagtgagggc
     1081 aatcagagga acggataatg ataaataagc tgtaaaaaat agcaaaataa caataatgat
     1141 taaaagtatg taaaaaatag ggctttgaca aaaacgtgtc acagccctat ttcgattaaa
     1201 cggtgtgtac ctgtcaactc ttcggtcaca agtcataatg ttcataaaca tgaggagctg
     1261 ttttttgaaa ttgttccttg tgaatcagag ttaaacgaca ggcttacgaa ctcttgatta
     1321 aacggcgttc aaaagcttgc atacgcggta ataagaacag ccaggtcaaa aacatgagaa
     1381 gccgtttttc ctgggctgtt cttattactt gatgcagggc agctttttca caacctcttt
     1441 attcagataa aaccaagctt ggatcagcat tcaactgata gctagcaaaa tttctttttt
     1501 gcatttccac atgtgctgct gctccaatca ttgcagcatt atctccacaa agtcgaagag
     1561 ggggaatcac tagttctacc tcagggagtt tagctgccaa agcatcctgc aatccttcac
     1621 gcaacccttg attggccgct acacctccag ctataatcag ttgcttgact ggataatttt
     1681 gacaagctcg aagtgtttta gtaatcaata catcgatcac acttgcttga aagctagctg
     1741 ctaaatcatt tttgtctaga tcttctccac gctgttgtgc attatgcacc aaattgataa
     1801 atgcactttt taatccgcta aaactgaaat cataattatc ttcatggatc atcgctcgcg
     1861 gaaaatggta attatctttt ccctgatgag ctagctgatc gatttctttt ccgcttgggt
     1921 aagaaagacc taatactctt ccaactttgt cataagcttc tcctgctgcg tcatctcttg
     1981 tctccccaat gatttcatat gatccatctt cttgcatata gactaattct gtatgtcctc
     2041 cgctaacaag aagtgccatc aatggaaact ggaatggttt aaccagacgg gctgcataga
     2101 tatgccctgc catatggttt acaggaataa gcggcaattg gtgtgcccaa gcaaaagcct
     2161 tagctgcaga aataccaatc agcaacgagc cgacaagtcc tggtccataa gtgacagcga
     2221 ctgccgataa atcttctgcc gacacaccag cttctaccag tgcatcttcc aagcataagg
     2281 tgatttgttc tacgtgatgg cggctagcta cttcaggtac tacgccacca aaacgtttat
     2341 gactgtttat ttgagaagca acgatgttag ataagatctc tgttccattt ctaacgaccg
     2401 ctacactcgt ttcatcacaa cttgattcaa tcgccagaat caattcttca ttcatttcat
     2461 cgtctccgtt tttaactttc tgctcataat gatcgcatct tccgtcggat tgcgataata
     2521 tgatttccgt ttacctaata tacgaaactt ttctgattca taaagttttc ttgctgcttc
     2581 attagataga cgtacttcta aaaaaacatg cagcgaatct tttatttgtt ccgtaatcag
     2641 taattgtaac aaatgccgtg catgcccttt tccttgttct gaaactgcaa cagcaatatt
     2701 tgtgatctcg acttcatcta ttactttcga gtatccaata aagccacaga tctggttatc
     2761 ttcagctaaa agcagataat cagagtgagg ctgttggatg tctgccaaaa actgcatttt
     2821 cgtccaaggt gaaccatgtg gataagcatt ttcgctaatc atccatacgc attctgccaa
     2881 gtacgcttca tcaaaatctt tttttctgca aatcaactaa tctcactcat tttctaaaag
     2941 ttttatcata tccaacgcat cttcttttgt ttcagtgtaa tatctttttt tgatcgttgt
     3001 tgcttgaaac cccaatttcc gataaagtct ttgtgcatct tgattactca tacgcacttc
     3061 taatgacatc gtctcacagc gattcattat agcaaagttc tcgatttcgt caataagcag
     3121 cgaaccgatt cgtttacgct gatatgccgg tcgaacggca atattcgtga tatggcaatc
     3181 taaaccgaac gctcttgaac cgataaaacc aatcattctt ccattatcaa agatacctag
     3241 atatagatga ggaagcggtg acttcaattc tgatataaag gcactttttg tccatggcaa
     3301 ttcgccatta tagacttctc gttcgacatc cagcagctct ttgatatctt ctgtagtcaa
     3361 ttctcttagt acgtaacgac gatcgatttg ttcgactgtt ttttctgtat aaatcatttt
     3421 atcttgaaaa aagcttctgg catacgctct aaattttttc aacataactt tcgtctccag
     3481 gtgtgtgcgt ctccaaccat ttttcttctg cttctactcg ttttaaatag cgaggaagaa
     3541 aagcttgttt ctctgcaact ggttcaacta aagcacctaa ttgagccaca gttacaccac
     3601 ttggaatatc ccatgctgga actgtattaa tcatcgcact aggcaatatt tcctttattt
     3661 cagagaagaa tttgtgacaa tcactcccga cgaaataaat agcttcattc agcttttgta
     3721 gttgtgtgaa caaatcagaa gcagaaatat gtacatcttc aagtacagtt tctaatctat
     3781 tttctttcca gcggtatgcc ccagcgtata cattttttct tcgagcatca aacatgggca
     3841 caataatatt atccacaccg atgcaattag ccgcgatggt tttcagacta gatactccta
     3901 ctagctcttt atctaatgta taagcaatcg tttttgctgt cgttacacct atacgaagcc
     3961 ctgtataaga accgggacca tcagaaaccg cgattcggtc aatgtctttt ggacttattt
     4021 gaagatctgc aaacaattgg tcgattgcag gcatcagtgt tacactgtgg ttgcgtttga
     4081 tatttgtttg tatttgtcca agaatttgtt cgtcttctac cacaccgatc gccaaagttt
     4141 ggtttgcagt atctattcct aatgtaatca tatatttgat cctttctgct atgacattct
     4201 cgccttccat tgtagcatac ttttttattc tgaggatgaa aataccaaag gcaaaactag
     4261 tacaataata catgattatc tgctggcggg caaattttgc cccttcctga aacacaaaaa
     4321 agctgcggta tcactccatt ttcccacagc ttttccatct tttatttcgt tgattctcga
     4381 ataatcaact ctgtttccac aataatcttt cttgaaaccg gtgctttgga attacttaat
     4441 tgaagaatcg tctccactgc tagctctccc atccattcgg tataaacttt tacagtagaa
     4501 agcgagggcg ttacatattt cgctacactg acatcattga agcccatcac agaaatatct
     4561 tctggtacca ctaaaccttt ttcttgaatc gctttcagtg cgccaatcgc taatgcatca
     4621 ttagctgcaa aaagcgcatc aggaacatgc ggattcgttt ttaaatattg cttcactgct
     4681 tgatatcctg actcgacaga aaaatctgct tcgataattg gaccttcgtc gtagcctttt
     4741 tctgccaaaa cttgttgaaa tgccataatt ctgggatctt ttagccgctg atggtttttc
     4801 ttcgtatatt ctgttccagc aagcatagcg atatgttgcg ctttatggga gacaaagtgt
     4861 tcaatgactt tttgaacact tgacttaaag tcgacaacta gagagtcgat tccttgagaa
     4921 gtgccgtcag aatctaccaa aagcaaggca ttttgggatc ctttcatttc taataactga
     4981 gcttcgtcga attttcctag tgcgatcgtt ccatctgccg gaagatcact aatggaatcc
     5041 cacgtttctt tcaataaagt aacgtttgct tcttctgcct ttttttcgat tcctaggcga
     5101 atagataaat aataaagatc ttcaagctct tccgtatcgt cgtaccactg gatcaggcga
     5161 agcgtttgct tagtatttgc tgcattttta cgatgtttcg tataatttaa gcgttctgct
     5221 gcttcaaaaa ttttttgctt tgtggctaag ccaacggaaa gatcaggatc atagttgaga
     5281 actcttgaaa cagtagcagg agaaactcct gccaactgcg caatgtcttt aattgttgcc
     5341 atttgtctct cctccttttt tacgtttata aaatcgcagt aaatcgttca aacgctgcct
     5401 gtcctttttc atctcgcttg aatactccag cgtcttccag tacacgtgca aaaacctgac
     5461 ctacagattt ttgtacgaca tcggtgaccg tatctttcgt caaatcagga tgttcttttt
     5521 ttaattgttc tgcccacgga cgatgatatt cagccatctg gttttcttct cctaataaga
     5581 aatgctctac ttctactagt tctggtttca aacgaggtgg taaaacagca agccccatta
     5641 cttcgatcaa cccaatgttc tcctttttga tatgttggac atctttatgt ggatgaaaaa
     5701 tcccatcagg atgttcttct gaaacattgt tgtctcgaag gacaaggtcc aactcaaagt
     5761 aattgtccct tcttcgtgca attggcgtaa tcgtatggtg tggtgtacca tctgctgaaa
     5821 aagctctgat agatactgtt tcatccgaat atgctttcca tttttccaat actgagttag
     5881 ctgcttcaat aagcaagttt ttctctgttg attgcaaacg gatcacagac atcggccatt
     5941 tcacgactcc tgcgatgact tgcggataat cttctagttt gataagtttt tctatcggtg
     6001 cttttgccat aggaaattca tgacgtcctg cctgataatg atcatgagaa agaatcgatc
     6061 ctccaacaat tggtaagtca gcattcgaac caacaaagta atgaggcaag acttcagtaa
     6121 tccgaagcag tctagcaaat gtttcctttg tgattttcat cgggcggtgt tgttctgata
     6181 aaatgatcga atgttcattg taataagcat aaggggaata ttggaatccc cagctttcac
     6241 cgtctagatt cattcgaata atccggtgat tggtgcgggc tggatagttc aagcgacctc
     6301 tatatccttc gttttccatg caaagcatgc aggtaggata gtctactttt accgcctcgc
     6361 gttctgctgc gatttgtttt ggatcttttt ctggcttaga taaattgatt gtgatttcca
     6421 gttcaccata ctccgactct gccggaaatt tgatgttttt tgcgatggct cttgttttga
     6481 tgtagtcatt tttcttactt aaattaaaga aatactcagt tgcttcctct gggcttttcg
     6541 aatagtgctg tgcaaagaat gcattgacga ctgaaggtgg cggtgtgaga aaatccatta
     6601 attgcgcttc aaaaatctct tgttctgctg gcaattctga aagaacacca ttttctcttg
     6661 ccttagcgac aagctgatcc aataagtcta cagattcttc cttaactggt cttacttcaa
     6721 tgctttctag agcatcttct cctaccatcc ctaaaagacg attctgtaaa tataagcggt
     6781 ccatttccat ccatccgcca gcttcgatcg caagtgtggc aaaatcacaa atcgtttgac
     6841 tgattgacat atctcattcc cctattcttc ataaccattt ggatggctga catgccaatc
     6901 ccatgctgtt ttgataatcg ctttgatatc tgtgtattca ggtttccagc ccagaatctc
     6961 tctcgctttt tcacttgaag cgactaatcg gctaggatct ccagctcttc ttggtgctat
     7021 ttctgctgga atttcttttc ctgtcacttc tctagctgct tctagcattt ccttgactga
     7081 gtatcctttg ctgctgccta aattgaagaa gttgctttca tttccttctt tcaagtattc
     7141 caaagctaaa atatgtgcag caatcaaatc ttctacttga acataatctc tgatacatgt
     7201 tccatctggt gtatcataat cgtctccata aacagccaag gcttttcttt gaccaagagc
     7261 tacttgtaaa atgattggga caagatgcgt ttctggtgta tgatcttctc cgatagatgc
     7321 atctgctttt gctccggcta cattgaagta gcgcaaagcg acatagcgca tgccatatgc
     7381 ttggtcacac cacttcatca ttttttccat catcaattta ctttcaccat acggattttt
     7441 aggattagct ggtgtatctt ctgtgattgg agactctttc ggctctccat aagttgctgc
     7501 agtagaagag aatacgattt tattcacgtt gaactcgtgc atgacttcaa gtaagatttg
     7561 cataccgtat acgttgttgt tgaaatacat caatggtttt tcgacagatt ctcctactaa
     7621 agagcttgca gcaaaatgga ttactccttc aatcggttcc ttttcaaata cggaacgtag
     7681 aaattcttta tcccggatgt ctccttcata aaaatgagca tctggatgta ctgcttgttt
     7741 gtgacctgtg agcaaattat ctaccacagc tacttgatac cccttttgaa ctagctggtc
     7801 tacagcgtgc gaaccgatat aaccggctcc gcctagtact aaaattgtca taaaaaacac
     7861 tcctttgatt agtaaaattg tgtttgttga ttctatataa tttaaaaaac gaagtttact
     7921 tttatggtga aaacaaacaa agtaaaattt cgtaaattca tatggtaaat ttataataaa
     7981 acatttagta aacattttca agggtttttt gcaaaggttt acaaacaaac gtaaaactag
     8041 cctttttttc tcttttgttc cataatagat ataacaaata ataaatgagg tggattcaat
     8101 gaaaaaattt gtatctggaa tattagtagg aagtctggca acagccgctg ccgttgctgg
     8161 tttggttgct tctgtgaaaa aaacagtgat cgatccaatt gacgaaaaag aagcaatgat
     8221 cgaagaaaac cgtaaaaaag caatgcgtaa acgcgtttct cgttaataat tatttaaaaa
     8281 tacgcatgaa gactttctaa aaaacagata agtcatcatg cgtattttta tttgtcagtc
     8341 aatataagtt gtgctatttt atctgcctgt ctcagattcc atggatctgt ataaggtcta
     8401 gctactgctg cagttagcca atccacacct tcaacaggta ttccatagca ataaaagtca
     8461 gactggattt cccctgaagc atcaatcacg cgattcgtac ctcgctcaac atctatagct
     8521 tctgaatgat aacttcctgt attatctgaa aatgaaaaag ggcgaacaag tttgttttcc
     8581 ttcaaatttt ttatgacagg attacttgaa cgagaaaagc ttgtttgtgg caatcgagct
     8641 tcaatcaaat agcgactgct gatttcttta tcttgtagag aaataacata gcggttgtgc
     8701 ttttgctgaa tatcaaatgg cggttcgatc aaatgaaaaa tacccgcatc tatcagtgct
     8761 gctaattctt tcgtccgaat gattggcgga ccgatcgtta aaaagctatt tagatgagta
     8821 aaccatcccc atagtatttc tttgtattcc ttagcagaaa aaacgtgcca ttcaatagcc
     8881 tgccggattg gatcacgcca gtcttttaat gcatcaaatg ttgaagcaaa tgctcctgtg
     8941 caattgcctt tttccgcttc ttttatctgc ccttcaataa atattcggct agcttctgaa
     9001 aagggctcat tctgataggc aagaggagtt tctaaatacg accaatccca tctataaggg
     9061 attagtgctg gatgctttcc gagacactcc tctgaagaga gggagagaaa atcatgctca
     9121 aaatttttct ttggaatcgg caagtgatat tcttcgatga ttttcttgta ataaaacaac
     9181 tcaacgtctt ttttcagata gtcaaaaaat gtttcgccag tcaaaaatcc cgactgatgc
     9241 cattgctcca ggttttcttt tgttagtaac cgtggccatg ccattgctcc gccttgcttt
     9301 tgatttcttc ctcgagggta ataagggagc ccccttcttg atccactgta tacaatcggt
     9361 tccttgcctg atggatgata gaccagtttt cccttttcgt tctcgaagcg ccctcctctt
     9421 gatactgtaa acaatccgac ataatcaaaa aaacttaagc ctagacctct taaaaagaca
     9481 ttttctttag gcggtatctt cgaaagatct acatctgcag gattagaagg aagctgatac
     9541 agtaaaacat ttttctttgc gtagtctacc cacactcttt cttcttctgt ctcatcattt
     9601 tcccagtgac cgcttgctaa aacaagctga tcgatagaat agctttgctg atctgtctgt
     9661 aaaagataac catcttttct tttgcttact ttttttacta aagaataaac aaactgaata
     9721 gaagctggaa attcttcttg caactttgag aaaaaccagc gttgatagag tccgtataaa
     9781 catcgagtag attgctgatc tttttccaga cgattgattt cttctataat tagttgctta
     9841 tttttggtta ccgtctgttc gatataatct gtagcaggtc ctttactcca ttgaaacaag
     9901 ttgggtccct gtgttaccaa tcctccactg gacaatgttt catctgtaaa aagcgtcact
     9961 tgttgagaaa cagaattcat taataactcc ggtggctgat tcaaccgcca aactcgacct
    10021 ccaggaccat tgggatcgaa aagaaaaagt tcaagagaat gtctgtcctg attattatgg
    10081 agaatccttt ctgctacact taatcctcta ggtccggcac caatgatccc tattttcatt
    10141 tgcatgcctc catttcgata aattttttca ataaaacagc atggttctga tgttcatttt
    10201 ttgcaccata aacaaaagta atgactggat gttctttcat aagttgactg agtttaaaaa
    10261 tagcttgctt cttttcttct tcgaaaatca attcttgctg gtatttcttt gcaaatgaag
    10321 caaatcgttc tggtacatgg tcaaaagttt tgcgtgcttc attactaggt gcaatttctt
    10381 tcaaccacag atctaactgc gctttttctt ttgaaattcc tcgtggccag aatctatcca
    10441 cgagtattct atagccatcc tctttttcag catcaaggta aacacgtttt aatttgatca
    10501 tagttgtttc cttctttcta ccttttcgct tagcttatat atgtagataa tagcacaaaa
    10561 taaaaaaaat gaacggcaca actatccatt gcgccgttca tgtgatcttg gtcaaaatct
    10621 aatgattgat tcggttttta aagctgtcat acaatcatct gttttatact tttttacttt
    10681 tgatttttcc agaccatccg tcatatccac ccttaagtaa ataaatctct tgataacctg
    10741 ctttacgtaa tttatttgct gtacggatgc tcaaactttt cttttgatcg taaatataga
    10801 caggctggtc ttttcgaata gatcctaatg aatctttcaa aacagtgtaa gggatgtttc
    10861 ttgcacctaa aatatgccca gcatcaaaca catctttttc gcgaacatcg attacttgtg
    10921 cttttctcat tccttctcga aattcttctt ctgtcaaagt cgttgctgaa cgtttggcca
    10981 ttactcgtag atagacttcc caaaggatga ttgcaagcac aatcaatagc aaaatgatat
    11041 taattaccca taaaaccatg taatgcctcc gtttttttaa gcaaatttca aggctaatga
    11101 ggcagcacca atgacaccag cttcattacc aagctctgct aatttgattt ttgttgattc
    11161 tcttacttgc gggaaagtaa attctttaaa atatttctct acacggctac gtaaaaattc
    11221 tcctgctgcc gatactcctc cacctaacac gatacttgac ggatttaatg tattccccaa
    11281 gtttccgcaa gctaaaccta agtagaagca tacgcgatca acaaccatca atgcaaacgg
    11341 atcgtcttct tgagccattt caaagatatc tttacttgtt acttcttctc cgttgtctag
    11401 cattgctttc agttttgaat cccctgcgta ttcttctgcc aagaaacgac ctaggcgtac
    11461 cacacctgta gcgctagata cagtttctaa acatccgcgt ttaccgcaag tacattcgaa
    11521 cccttcagga tccacagtga tatgtccgat ttctcctcca gctccgctca cgccgtgaat
    11581 caaatttccg ccagcaacga tacctccgcc aacacctgtt cctagagtaa cgaatacaac
    11641 gtctggatcg ttttctccag cacctttcca tcgttcacct aaagcagcaa cattcgcgtc
    11701 attatcgata gcgaatttga ttcctgttcc tgcctcgatc agttttttca caaattgaac
    11761 ttctgtccag tttaagttat acgcaccaat aaccgttcca gcttcgctgt ccacgcttcc
    11821 tggggtaccc atgccgattc cgataaagtc ttcggctttc atattatata aattcaaacg
    11881 atgattgatt gattcaatga tttcaggaac gatatgctta ccatcatcca aaatattggt
    11941 atcgatgctc catttttgct gaatctctcc ttctggtgtt aaaattgcaa attttgctgt
    12001 tgttccacct aaatcaatcc caataatctt cttgtccatt acaaatttcc tttctttcgg
    12061 ctttcttcaa ttcggtgctc tctttttaat atgcgccacg ctgtcatgta tgtatcatga
    12121 tcaatcaaac ggctatcata cagattacgc aattcgatag tcattaattc aatgtcatag
    12181 atgcgtgcac ccacatagat aaagatgcca aattttttga acagctgctg tacatcatat
    12241 aagctctcca tctttaagca cttccttcat attatacaag taaaccatat ttttttaaac
    12301 ccagtaaaat acatattaca aaaagaaata caaaaactag tgtagaaaga atcctttggt
    12361 gtatcgaata gcttgtctgt tgtttcggta gacccaaaac attccctaac actaatccgc
    12421 caattagccc accgacatgt ccccaaacat ctacagaggt atccagaaga ccaaaaacaa
    12481 atgtcaacac aataaataaa agaaaatgtc tgactagctg ctggatcgct gggttatgtt
    12541 taaaatgaaa ccctaagata aacaacgcac cgaacaaacc gaatatcgaa gtacttgcac
    12601 caccagacag aacattcgct tcgttaaaag caaagcttgc tgtatttccc attatcccgc
    12661 tgaacatata aatcaagaaa aaacgccaat ggccatagat tgcctcgatt tgctgcccca
    12721 taaaatacag tatcagtgag ttcattacga aatgcatcag tccaaaatgg atgaagattg
    12781 gtgtcactaa acgccaccat tcattgaagt gaacaagata aggaccatac attccggcat
    12841 aataagggat ctcaagtcgc ggaaataatt ccatcatgag gaagaccgct gtctgtatcc
    12901 ctaaaaaagc ataggtccat aacggtcgtc ttaaccatgc acgcaatttt atttgctgtt
    12961 gataattcat gaaaacctcc catttcattt tagtcaataa acaattgttg gatcttctga
    13021 tcaaagctct ccggttgcca ttgttcattc aattgttcac gaaaaacaag gctacatgtt
    13081 tttttatgaa aattatttaa ataccggtcg taataaccac cgccaaaacc gattcgataa
    13141 ccggctctat tgtagataat acctggtaca atgaggagat cgatcatctc cggcaaatag
    13201 agcttctctg attgtggctc aagaacacca aaactcgaac gtacaagaac ggactgttca
    13261 tccatttcat aaaacgccat ctgacgtttc ggcaaagttt taggtacaac tattttcttt
    13321 tgttcttttt ctgctcgttg gataaccggc tgtgtatcca gttcaaattc attcgataaa
    13381 gtcgtcccta tcacttttgc tgacttccag tactcgctgg cgaatagctg tttatagatt
    13441 cgctgttctt tttccttttt cttgccactt ttggccagat ttttcagctt ttcgattcct
    13501 ttccggcgta atcttacttt caattggtcc aaaaactcac ccttccttct ctcataaaat
    13561 ggtataggaa aaaaagaaaa atagcaatcg aactttcaaa taaatgcata aatagaataa
    13621 aaagaagacc tagaaatgat tggccttcct tttttaatga atttcaactg ttcagcgcgt
    13681 gtttttgtct gataaaaagt gcatacagaa aatatggcgc accaaaaagg gcaatcaaaa
    13741 ttcctgtagg tacttcccca cttggtagaa tcactctagc aaccatatct gcactaagca
    13801 gaaaaatgga accgaacaaa ccgctcagaa caaaggtcca gttattttct ttacgtacga
    13861 ctagcttcgc agcatgagga gctagtagtc ctacaaaaga taaactacct gtcaccgcta
    13921 cactaccgct tgccaaagca acagctaaca acaaaaggat tttttgactt ttagccacgt
    13981 taaggcctaa tccttgcgcg cgttcttgac caaatgatag caatacaatc ctctgtgcat
    14041 aaagtcctcc tagcggaatt aagataaccg cccatggaag caatgcccaa acataaggcc
    14101 agctcgcacc ccagattgat cccgctaacc atgcattcac aaatccataa ttttccttag
    14161 ataattggat cgtgcatagc aatgttaatg cagaaaggcc ggcattaacg gcaataccgg
    14221 acaataagat tcgattcata cccaaaaagc catttcgatc ataggccgca agatagacac
    14281 agcaagcagc taaaacacca cctagaaagg ctacaactag caatagaaac ggcagcgaat
    14341 agtgcgaaaa gaaacctaaa taaagcatca ctaaaaatcc tgctccggca ttaatgccca
    14401 atatactaga atctgccaat tcatttcttg ttactccttg caagatataa ccagaaacgc
    14461 caagacaagc tcctgctaat aaactgatca gtaatcgagg aactcgaaat tctctaacaa
    14521 tcagcgccaa agaagatgat tctttcccta tgaacgtggc aaaaagctga tccaggtaaa
    14581 taaaaggcgt accaatcatt aaactaccta tagacaggat gacaagtaca aaaagcaaga
    14641 aatagaacgt ccaatatatt tttttcaccg ttgttccctc cttacttgta tcagtaaaaa
    14701 cggaacgcca atcaatgcaa tgactaatcc aaaaggtgtt tcaaaagggg gattgatcat
    14761 cctcgctgta aaatccgcca acataaccaa tccaccgcca actaaaaaag agacaggtag
    14821 aacataacga tagtccgttc caaccattcc gcgaacaact ggcggaacca acagcccaat
    14881 aaatgaaaca ggtccgacta acgaaacggc aatggctgct aacactgcaa ctagacagaa
    14941 aacaatcaac cgcgttcgtt taggatgact tccaagagct aatgcatgtg tttcactcaa
    15001 atgaatcaaa gatattgctt ttcctaatga aaaagaaacc aaaacagcaa gtatatataa
    15061 aggaaacaat actgctaatt gtttccatgt gatattggca gctccgccta caaaccaaaa
    15121 agcaagatcc tgctgcagat taaagaattg ggtaagtgct tggctgatag cagtaaaaaa
    15181 agaactaata gctacgccag ctaaaatcag ctgtaaagga ttcatgccca ttttcgaaaa
    15241 ctgcaaaaaa ccaaatacga gcaaagttac agcaaaagaa cctgccaatg acattagaaa
    15301 cacagaaaaa tcagaagctt taggccaaaa agcaaaacta agggccattg ccaacgaagc
    15361 acccgcgttg attcctagta agcctgaatc tgctaaagga tttcttgtca ctccttgcat
    15421 caatgcaccg ctcaatgcaa aacaactccc tacaagaaat gctcccgcca cacgaggcaa
    15481 acgaatattt cgtatgattt ggtgactttg ttttgatcta tcaaaatcaa acaacgcctg
    15541 ccaaaaatct gctttttcca cagtcgctgc gccatttgaa agagcaacaa aaaaaataat
    15601 caaaagaaca aaacagacca aaagcaggag tctatttttc ttcatagtcc tcataattga
    15661 tcctcctgct cttttggcaa caaatcatag gttagaaaaa ctggtttatt tgttcttgga
    15721 agcgtgacaa tcgttgcatc aatctcaaat atttttttca tacactcttt tgtgatcact
    15781 tcttcaggtg taccttctgt gatcaactta ccgtttttca ttgctaataa ataatctgaa
    15841 aaacgtgaag catgattaat gtcatgaatc gacatcaaga tcgttgtttg tttcatttga
    15901 ttgatttcag tcaataactg taggatctct aattggtgtg ccggatctaa aaatgttgtc
    15961 ggttcatcca agatcaagat atctgtttcc tgagcaagcg ccatagcgat ccagacacgc
    16021 tgggtttgtc caccagacag cgttgcgata tcccgcatac gaaatccagc tagacctgta
    16081 gcatccaacg cccactcaat tgcttcatga tcttgcgtgt ccatgccact gaacagtttt
    16141 tgataagggt atcgtccgta agatactact tcttctactg tcatacctgt agggtgttca
    16201 ctagtttgtg ctaataatgc aatttttttt gcaagttctt ttgaactgta tgtagagata
    16261 tcagagttat tgacaatgat ctttcctgat ttcacaggta gtatacgggt aaaacttttc
    16321 aataaagtag attttccact tccatttggc ccaatcaaac tagtgatttt cccttcagga
    16381 atcgtaacag acatgttttc aatgattttt ttgttttcgt agccggctgc aatgtcagct
    16441 gctcttaatc tcgtcatttc acccatcctt tcgctgaaaa tcattctcaa ttatgacgct
    16501 gtttcaacat ttcgtcaagc gctactttca tatctatagc caaatgaagc ggttgacagc
    16561 gttcgaaata tcaggaataa taaccaatga gaaagattct caattatgtt aggaggaaag
    16621 aaatgaaatt aaaaacaaaa gtattcacat tatctagcat attgctgctg gctggagtac
    16681 tgagcgcttg ctccccctct tcagataaag aaacagctac aactgccaat tcgacgactt
    16741 catccaatag tactcataca gtcacagata cacttggaca taaagtagag attccaaacg
    16801 cgcccaaacg gatcatcggc agttacttag aagactatct gattgcacta ggggaaaaac
    16861 ctatcgccca gtggactgtt ggcagtggtt ccattcaaga ttatctgcaa gatgatttaa
    16921 aggatgtccc aacgatttct tatgaccttc cttatgagaa agtgttaagc tttgagcctg
    16981 atttgctgtt gatttcttct tccgctactg tcgaaggcgg gaaatacgaa caatatagca
    17041 aaatcgcgcc aacttatgtt gtaaaaaacg gaacagatgt cacatgggaa gaacaactaa
    17101 aagatgtcgg caaagctttg gcaaaagaaa aagaggcaga aaaaatcatt tccgattatc
    17161 aaaaatccat caagaaaact cgagaagaac tagcagataa aatcgagaac aagacagctg
    17221 cagtgttgtg ggtgaccaac aactcagcct ttatggtcag caaaaatcgg tcaagtggaa
    17281 gaatcgtata cgacgatctg gaatttggtg ttcctgatct agtggaagag gtctccaaaa
    17341 aagccacttc tgactggtct gctgtttcct ctgaaaagct agctgaatta gatgctgact
    17401 acatcatcct tgtgaacagt gacaaagatg ctgccatgtt caatgaacca agctggaaga
    17461 atctaaaagc agtgacagac aatcatgtac tgcaattcgg acctgaatct agttggctat
    17521 ataacggacc tattgccagt caggaaatgg tcaatgatat caaagaaaaa ctaaattgat
    17581 tttaactaaa aaaagcatct tcacgattag tcgtgagatg ctttttttct tattaacaaa
    17641 ctagacgcat agattttatt cttcttttga agcaacccta ttttttactc tttcccattt
    17701 ttgaaaacga tgggcatata gattttcttg atccgttatc ccctcatact cctctataag
    17761 ggcgaagtct gaaaaatcaa tattcccaat atacgtatcg ccttcaaacg tgctatcgat
    17821 caatgttcgc cagatccgac cagtgtaagg aagaagttct tgaaaaatcc gactaccacc
    17881 cgaaacatag atatcttctg agatcgtttg actatacgac aaaagttcat cgatcgaatg
    17941 cattacttcc gcattttctt tcgtgcgaaa atttggttgc gttgtcaaca cgatgatatg
    18001 gcgataagga agtgaaagat cccccattcc ttcataggtc tttcttccca tcactaaaat
    18061 tcgatccatt gtatgttcgc gaaagaaacg catatcattt ggcaatcgcc atggtaacaa
    18121 accatttttg ccgatcagac catttttatc ttgtgcccac atggaaataa acatattatc
    18181 cgctccttat gattttagat gttttgagat aaaaaaagtc tcaattcttt gaccagcaag
    18241 gaattgagaa ctttaaaaac attattttgt ttcacggtgc aaagtaactt tgcgttcgcg
    18301 tgggcaatat ttttgttttt ccaaacgatc aggattgtta cgtttgtttt tgcttgttag
    18361 atagttacgt tctttacaag aagtacactc taaagtgatg tttacgcgca tgtttttccc
    18421 tcccattttt acaagaatcc tctaagatga ctctcagact tgattatctt accatgattt
    18481 tttctagatt gctagtgttt ttcacgattt tgttaagtaa aactacttga cgataaatac
    18541 aacggtttta cttctcaaac aaaatctttt tctttttgta taaataccct tacacttgtt
    18601 tatatagatt atgtttttta ataaaggggg atactaatat gccatggaac atgaaggact
    18661 ttcctgcatc aatgaaaaac ttagataaat tgacaagaaa aaaagcaatc gacatcgcaa
    18721 atgcattatt agatgaaggg taccctgata accgtgcgat cccaattgcc attgatcaag
    18781 caaaaaaatg gtatgaagat gctagtgaat cagaaaaacg aactttcgaa aaagaaaaaa
    18841 atccaagcaa gacggatgaa cacgatacga atcctcgtgc tggaaaactg cttgattcag
    18901 atgtgatcgt agaatatgag gaagaacaat ggatcgtgaa atctaaaggg gcaaaaaagg
    18961 caagcaacca ttttgataca aaaaaagaag caatcgaaaa aggaaagcaa gtagcacaaa
    19021 acaaagaatc aactttgttc atttataaaa aagatgggac aaaagaaaaa gaaatcgatt
    19081 attgaacata tgtaaagggg ttgtgacgaa aatcgtgtca caaccccctt atgttcgaaa
    19141 caatggtgtt cctctgccaa ctccgaacca taagtcataa tatctataaa acgggaagag
    19201 ctgttttttg aaattgtttc ttatcactca gtgttaaacg gtaggagaaa acctcttttt
    19261 tattgatatt tgattttcat caaacagtca catagtcgat tgcttctgct tgcggaatcg
    19321 tttcatctac aaagtagact ttataccatg tcaagaaact gaagattgtc cagatttttc
    19381 tttgctcttc tttacgtcct tcgtgatggt catctagcaa cttcatgatt ttttcttgat
    19441 caaaaaattc ttttgcaaaa tctgcttcga ataatgcttt gacttgttcg tagccgtgtt
    19501 cttctttcaa ccaagctttg attggcacag ggaatcctaa tttcacacga ttcgaccatt
    19561 cttccggaag atgtttgttc gcagcttgtc tgaaaatatc ttttgtgttg ttttgattca
    19621 ataaaaactt acttggtatt tgttgagcca atttcatgac ttcgatatcc aataaaggta
    19681 ctcggacttc caaagaactt gccatagaaa gtttatctgc ctttaacaag atatcttttg
    19741 gcatccattg atgaagatcg acatattgca tcttattgac ttcatctttg attccttctg
    19801 ttttctcgta atgaacagtc atgatttcat ccacagatgg tgctgtttga tattttggtg
    19861 ttaacacttc tgatgcttct gattcttcga acactcgagc atgaccgata aaatattctt
    19921 ttgcaggagc aagtgattca tataaatgga tccgtccatg gaagtttttc atttttccga
    19981 ttttacgtcc taaattatag cgtgttcctt ttggtaattt tttcaatcct tgagcaatca
    20041 cacggatgaa ttttgaattc gtatggaatc catacgtttg gtatcccgca aacagttcat
    20101 ccgccccttc tccagattgg actacccgca cactttgtga agcaagattt gctaaaaagt
    20161 acaaaggtac gcaagaagga tttgaatcag gttcatctaa gtgatactgg atcaaaggga
    20221 atgctttgaa cgacatgtct ccgtcgatca ctgctgctgt attatctaag tccaatagtt
    20281 cggttagttt tctggcttca atcgcttcat tataggtttt atcatcaaac ccgattgaga
    20341 aagaatgatc tggtttcaat acagaggtta cataactgga atcaaccccg ctggataaga
    20401 aagaaccaac ttctacatca ctgaccgtat gtgcttcaat agaagcttga acggtttcgt
    20461 cgattttttc gatccattct tgtcgggaat gcgtttcttt tgtttcaaaa tctgcatccc
    20521 aatattgctg aatgtctatt tttccatctt tatacgtata ataatggcct tcaggcaaac
    20581 gatagacatc tttgaagaat gtttcgccgt ttaatggaga atattggaaa gtcatataag
    20641 gtttcaacgc ttctttgttc aattctttgt taaaatcagg atgaggcaga aaacttttga
    20701 tttctgaacc aaacataaat gttccgttca tttctgcata ataatatggt ttgatcccaa
    20761 agtggtctct tgcaccgaat aactcattct tttcattatc ccaaatagca aaagcaaaca
    20821 ttccgcggat cttttgcaat aattctgttc cccattcttc gtaaccatgc aaaaggactt
    20881 ctgtatctgc atgtgtttga aaaacgtggc cagctgcaat caattcttct ctcaaaggct
    20941 ggtaattata gatttcgcca ttaaaaataa tgatctttgt ccgatcttca ttgtaaatag
    21001 gctgagtacc gccctctaag tcaataatac ttaatcttct gaatcctaaa gcaacatgtt
    21061 tatcgatata ttctcctgaa ctattaggtc cacggtgaac gattcgatcc atcattgtat
    21121 taataattgt ttttttgttg tccttgtcgt taacaaaacc tacaataccg cacatttaac
    21181 tttcacatcc taatataaaa ttactgttta tttcattcat atgcatctta tcatagaata
    21241 aatagcggac gaatattttc tctcttacaa tttcgtcacg tgaaaacaaa agatgaaagt
    21301 ttctgttttt acagaaaata aagtcccaat atctaattta ccatgttttc ttttttgagg
    21361 ctaccttatt ctcttcgtgt taaaaaaata ttagtggatg ctatttccaa aaaaaccagc
    21421 aaaaaaagac acgacctaaa gatcgtgt
//
LOCUS       DAIGSZ010000049        20361 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.049, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000049 DAIGSZ010000000
VERSION     DAIGSZ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.049"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            292..1431
                     /locus_tag="NOB31_001940"
     CDS             292..1431
                     /locus_tag="NOB31_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HCI0974144.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLARHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHSIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1498..2073)
                     /locus_tag="NOB31_001941"
     CDS             complement(1498..2073)
                     /locus_tag="NOB31_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0974145.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQVGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2078..3052)
                     /locus_tag="NOB31_001942"
     CDS             complement(2078..3052)
                     /locus_tag="NOB31_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HCI0974146.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPVDIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGLDGLGDTNFPMVLAKQAESL
                     HAVDFLTDYFKEKTDTSVIALGPLTNIASALKNSPSVGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFEKLKQPIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIDESICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3076..3120)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3335..4303
                     /locus_tag="NOB31_001943"
     CDS             3335..4303
                     /locus_tag="NOB31_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0974147.1"
                     /translation="MVIFYFILILIFIGISYHFLSYFYAKKLVRAGVQRGYDWYEETG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGIPKTIKSYDGLKLAGQMFLQPTQQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLIPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPDASIILHGSSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMIMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            4416..4694
                     /locus_tag="NOB31_001944"
     CDS             4416..4694
                     /locus_tag="NOB31_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCI0974148.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            4812..5048
                     /gene="secG"
                     /locus_tag="NOB31_001945"
     CDS             4812..5048
                     /gene="secG"
                     /locus_tag="NOB31_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HCI0974149.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            5151..5906
                     /locus_tag="NOB31_001946"
     CDS             5151..5906
                     /locus_tag="NOB31_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCI0974150.1"
                     /translation="MKRVKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVETNVPENFEKYVRQVLKIAGKSEKEINEKAVSYRSL
                     AEHQLMDIQDQAAIAESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5909..8266
                     /gene="rnr"
                     /locus_tag="NOB31_001947"
     CDS             5909..8266
                     /gene="rnr"
                     /locus_tag="NOB31_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HCI0974151.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILVEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSDEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDIVGRRDLRDQLIVTIDGEDA
                     KDLDDAVTVKKLENGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHEIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILEMMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8288..8752
                     /gene="smpB"
                     /locus_tag="NOB31_001948"
     CDS             8288..8752
                     /gene="smpB"
                     /locus_tag="NOB31_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HCI0974152.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9054..9773
                     /gene="atpB"
                     /locus_tag="NOB31_001949"
     CDS             9054..9773
                     /gene="atpB"
                     /locus_tag="NOB31_001949"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HCI0974153.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9826..10041
                     /gene="atpE"
                     /locus_tag="NOB31_001950"
     CDS             9826..10041
                     /gene="atpE"
                     /locus_tag="NOB31_001950"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HCI0974154.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            10132..10656
                     /gene="atpF"
                     /locus_tag="NOB31_001951"
     CDS             10132..10656
                     /gene="atpF"
                     /locus_tag="NOB31_001951"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HCI0974155.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10643..11185
                     /locus_tag="NOB31_001952"
     CDS             10643..11185
                     /locus_tag="NOB31_001952"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HCI0974156.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            11208..12764
                     /locus_tag="NOB31_001953"
     CDS             11208..12764
                     /locus_tag="NOB31_001953"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HCI0974157.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEETLNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12778..13680
                     /locus_tag="NOB31_001954"
     CDS             12778..13680
                     /locus_tag="NOB31_001954"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HCI0974158.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13703..15109
                     /gene="atpD"
                     /locus_tag="NOB31_001955"
     CDS             13703..15109
                     /gene="atpD"
                     /locus_tag="NOB31_001955"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HCI0974159.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15123..15545
                     /locus_tag="NOB31_001956"
     CDS             15123..15545
                     /locus_tag="NOB31_001956"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HCI0974160.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            16014..16244
                     /locus_tag="NOB31_001957"
     CDS             16014..16244
                     /locus_tag="NOB31_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HCI0974161.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            16341..17642
                     /gene="murA"
                     /locus_tag="NOB31_001958"
     CDS             16341..17642
                     /gene="murA"
                     /locus_tag="NOB31_001958"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCI0974162.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNCPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            17655..17831
                     /locus_tag="NOB31_001959"
     CDS             17655..17831
                     /locus_tag="NOB31_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCI0974163.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            17966..18262
                     /gene="yidD"
                     /locus_tag="NOB31_001960"
     CDS             17966..18262
                     /gene="yidD"
                     /locus_tag="NOB31_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HCI0974164.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            18326..18709
                     /locus_tag="NOB31_001961"
     CDS             18326..18709
                     /locus_tag="NOB31_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0974165.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHH"
     gene            18878..19762
                     /locus_tag="NOB31_001962"
     CDS             18878..19762
                     /locus_tag="NOB31_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0974166.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            19876..20112
                     /locus_tag="NOB31_001963"
     CDS             19876..20112
                     /locus_tag="NOB31_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HCI0974167.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            20200..20280
                     /locus_tag="NOB31_001964"
     tRNA            20200..20280
                     /locus_tag="NOB31_001964"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20234..20236,aa:Tyr,seq:gta)
     gene            20287..20358
                     /locus_tag="NOB31_001965"
     tRNA            20287..20358
                     /locus_tag="NOB31_001965"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20319..20321,aa:Gln,seq:ttg)
BASE COUNT         6759 a         3566 c         4425 g         5611 t
ORIGIN      
        1 tttttttgca actagcttct gtatatgatg tttacaaaga atggtacaag aaaagatcat
       61 ccttgaaaaa ggaaagctaa caataactag catcatataa gagcttttaa ggatagaaca
      121 gtagaatagg aatctatggg caagtcctct cgtataaata aaataggagg gaagtagcag
      181 catatttttc ataaagtggc tctctttctt catttttact ttggttgctc ctatttgaaa
      241 attcgagcac actcaaatac aataaaaaga aatggcaagg gagaggatta gatgaaaaaa
      301 gaagaaaaaa tcgcgatttt acaagagatt atccgaatta aatcagtgaa tggaaacgaa
      361 ggtgaagtag cagcctattt gaataagctt ttggcaaggc atgacataac aggagagatt
      421 gtttcttaca gagatggtag agataatttg attgctcgtt accaaaaggg ccaatcagga
      481 aaagtgttag gcctatctgg acatatggat gtcgtggcgg ctggtgatga atcgtcttgg
      541 acctatgcac cctttgcagc agaaatccat gggaaccgtt tgtacggacg tggtgctaca
      601 gatatgaaga gtggcttggc agcaatggtg attgccatga tcgaactgaa agagtcagga
      661 aaaccattta acggaacagt caaattatta gccactgtcg gagaagaagt gggtgaacta
      721 ggtggggaac agctcacgaa agcaggctat gtagatgact tagatgcctt gatcatcgga
      781 gaaccaacca attacagttt gatgtatacg cacatgggat caatcaacta tacagtcacc
      841 tcgcacggaa aagaagcgca tagctctatg ccagaccaag gttataatgc aatcaatcac
      901 ctaaatgaat tcattacgaa agcaaatgct gaaatgaatc acctcgctga aacaatcgag
      961 aatcctgtcc taggaaaaac aatccataat gttacattga tcagtggcgg gaatcaagtc
     1021 aacagcatcc caagccatgc gcagctccaa gggaacattc gatcgattcc agaataccca
     1081 aatgataaaa tcattgcatt gctgcaatca atcgtcaatg aattgaatca agagacagac
     1141 tatcatttgg aattgatgat cgattacaac aaaatacctg tcaaagctga tccagattct
     1201 cctttgattc attccattca gcaacaattc agccagccat tacctttagt tggagcggca
     1261 gcaacaacgg atgcagccga atttacgaaa gctaaccatt ccttcgactt tgtcgtcttt
     1321 gggcctggtg tcgttacttt gcctcatcaa gtagatgagt atgttgaaat cgataattat
     1381 ttggatatga tcgaaaaata tcaaggaatt attttatcct acttagcgta agattttttt
     1441 aataaatgaa aaaacagagc cagattagca ttattttgct aatccagctc tgtttattca
     1501 gcctattttt ctttttgaat atatcaagcg ttggggcaac atagtgatga ctaatgaaac
     1561 aacgacgata gacaacaagc gatcaaggta gtctgtaccc acctgtacca agatcacact
     1621 tgttgtctga cttaaaccta acccatgtaa tagctgaacg atcatactgg atcctgagga
     1681 ggtgatcccg ccaaataact gaacggtaat gatcgaagaa acgatcgttc caggtaccga
     1741 caaaatcaaa gcgagtaata acagtttcaa gctgttttta tctttgccga gatatcttgg
     1801 caaaatcaat ccagcaagca agcctgtgag aatttggatt ggcgaataat acagagaaaa
     1861 aatatctgta gtcactccac ttaaaatacc gctggacaat cctgtcagca ttccaggtac
     1921 aggcccaagc aatgcaccag caaaaatcgt tccgatagaa tcgagataga ttggcaaacg
     1981 aagccataaa gcaatcgttc ctccaatata attgatccca atacacaaag ccatcactgt
     2041 aagtacgcga gttgccattt tgtttttatt cattttgtta gcccatcttt aacctttcca
     2101 aatctttcat aatcgtttct tcttgtgcat ttaaaagaac ggttaaaaac tttcggaaaa
     2161 aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc caaaattcat
     2221 aacgatcaac caatgtttgt ccgcgactta ttccttgagt ttctacagca gtgaagcttt
     2281 taaagccttc acagatggac tcatcgataa aataagcaac agctaatgga tcattgatga
     2341 cacatcctaa gattctttct tgtttccagt gaaagtcaaa ataaaaacga gtgatcgctt
     2401 ttagatactc tccctcttca ggattcattt ggcagcaata ttcaaggata gtcggtgtca
     2461 agacgatttc tcttgtcaca tctaacccaa ccatttctat cggttgtttg agcttttcga
     2521 atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact ggtgaacagt
     2581 taccatggct tttgtaagtt ccgcccattg agacaaaacg atccatatgt ttcccaacag
     2641 atgggctgtt tttcaaagca gaagcgatat tggtcaaagg ccccaaagca atgactgatg
     2701 tatctgtttt ttctttgaaa taatcagtca gaaaatcaac tgcatggagc gattctgcct
     2761 gtttggctaa gaccatcggg aaatttgtgt cccctaatcc atccaaccca tgagtgtctt
     2821 gcgcactaat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca gggatatcta
     2881 aacgatcaca gcgctccaaa catttcagca cattctgcgt accgatatct acagggacat
     2941 tcccgcaaac gacggtaata gcaactactt cgatatcagg ggatttgaca gctagtgata
     3001 aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tactttacgc attatttcca
     3061 atctcctttc tttagagata cttagttttt tattctggga agtttccgaa ccagtccaag
     3121 acgagtgtct tgtttataat gcacgaaatt agtatactgg cttttattgt gaatgtaaat
     3181 gctctcttac aagtaaatct attgagaaga actttaagta aatgatacaa tgaaaaagaa
     3241 atggaattta cgtgtgccga agaaaaagaa tcctattgat cggtatattg tataataaat
     3301 agattatagt ttggcagaaa gcggcgggtg tacgatggtt attttttatt tcattcttat
     3361 tctgatattt ataggaatca gttaccattt tctttcttat ttttatgcaa agaaattagt
     3421 aagagcgggg gtacagagag gctatgactg gtatgaagaa actgggcacc gcttgatgga
     3481 tcctgctgca gtcacgtcag tagaaaaaaa gcgacaaaaa ttagaagaag agtgtgaaag
     3541 cttctgggaa caaggaatac cgaaaacgat caaaagttat gacgggttga aactagctgg
     3601 acagatgttc ctccaaccaa ctcagcagaa taaatgggtc atttgtgtac atgattatcg
     3661 aagtacaggg aaaagagata tgtctcatat aggtaaaaga tatgcagaga aaggattcaa
     3721 cgttcttata cccgatttac gtgcgcatgg agaaagtgaa ggagaaatca tcggaatggg
     3781 atggctagac cggctagatt taattgcatg gatccaactc atcttagatg aacaaccaga
     3841 tgcatccatt attttgcacg gcagttcgat gggcgcttct actattatga tggcaagtgg
     3901 tgaaaagctt ccatctgcag tcaaaggatt tatcttagac agcggatatg tttctgttta
     3961 tgcggaattt cggtatatgt taagtaaaat cacggtcttt cctaaaaaaa tgatcatgag
     4021 atatgcgaat cactatgctc agaaatacgc aggttattct ttaaagcaag catcagctac
     4081 aagacagctt ggtagtaacc atttgccttt gttagtcatc catggtgaaa gagatcattt
     4141 tgttcctaca gaagcagcat acacgattca aaacgctacg gcaggggata aagcattact
     4201 gcttgttcca gaagcagaac atttggaagc atcgatgaaa gatccgaaaa cctattggac
     4261 agtgattttt tcatttattg aacaaagaat aacgatggat tgattttctc ttcctttttg
     4321 taagcaacac gaggataaat aattgtttat agaccatgag actgttaaaa taaggtagga
     4381 ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagag gaaaaaaatc
     4441 gtcttgcttt attcaatgat gagcaacaag aaatcggaga aatgacatgg tcggatgcgg
     4501 ggccagacat catgatcatt gaccatacat ttgtcgatcc agcatatcgt ggtcaaaaat
     4561 tagctgaaaa gctagtgtat actggagtag aactagcaag acgagagggg aaaaagatta
     4621 tcccttcatg cccttacgca aaaaaagagt ttgagaagaa accagagtat catgacgtct
     4681 tacgccaatc ataataataa cagctgaaag atttgcactt tcagctgttt ttccatttat
     4741 atagagttgt cacggagttt tatctatgat aaagttaaag agacgatatc ttttgggaag
     4801 gaggctgcta tatgtataat ttaattttgg gaatcgtgat cgttttatcg attgttatgg
     4861 tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca tttaccggcg
     4921 gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc atgcagcgat
     4981 caactgcagt catgggagct gtctggatga tcttattatt tgtcctagca tttttatctt
     5041 cgaagtagtc gaataagcct ctcgcacaac ggcgggcggc tttttttatt gcaaagagaa
     5101 cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag gtgaaacgag
     5161 tgaaacaatt accaaaaccc ctttatgcaa aacatggaaa acgagcagtt ttgctgcttc
     5221 atgcgtactc aggaagtcca aatgatgtcc ggatgctcgc acggttttta gaaaaagcag
     5281 attatacagt ctatgcgccg ctatttaaag gacatggaac gatggagcca tatgatatct
     5341 tgcaagaaaa agcagaaagc tggtgggcag atactaaaaa agctatccat tttttacagt
     5401 ctgaacagtt ttctgatatt gccgtattgg gattatcgat gggtggcatc tttgctgtac
     5461 gggcactaga agaagaatca gtaattggcg gcggtttttt ctgttcgccc ctgtctcctg
     5521 tagaaacaaa cgtgcctgaa aattttgaaa aatatgtacg tcaagtgctg aagatagcag
     5581 gcaaatcaga aaaagaaatc aatgaaaaag ctgtgtctta ccgctcgtta gctgaacatc
     5641 aattaatgga tatacaagac caagcagcaa tcgcagaaag tagactatca gatatccaac
     5701 agccaatatt tttagctcaa gctgggaaag atgaaatgat cgacccaaat ggtgtatttg
     5761 aaacggcacg caaattgagc cgccaacgag tgacacttca atggtatcct gaaagcggtc
     5821 atgtgattac agttggcaca gcaagacgcg aattagaaaa agacgtgttg gaatttttag
     5881 aaaaattacc ttggaatgag gaataaatat gacaaaagaa acaataaaag agaaaattct
     5941 ctttttcatg gaaagcagtc gcaaacgtag tttttctatg gaagaaatcg ctgaaggtct
     6001 aggctttcaa aaaagcgatg attttaaatt actagtacaa acgattgctc aaatggaaag
     6061 agaacagagt atcgttttca ataaaaaagg aaaagtcaaa cttcctttaa aaccgatctt
     6121 ggtcgaaggg acatttcggg caaatgaacg aggatttgga tttgtaacga ttgatcccga
     6181 agaagatgat atctatatcc cgaaagaagc gactggcttt gcaatggatg gggataccgt
     6241 agcaattgat atcatgaagc gagcaaatac agatatggat cgcggagcag agggaaaagt
     6301 agtggagatt cgagaccgag cgactactca gttagccgga gaatttgttg cttattcaga
     6361 cgaagagata caggaaacgg atctttatgg tgtggtcatc ccgaaagata gaaagcttaa
     6421 ccaattcaaa gtgtatgcag cggcagaggg agttcgtcca gttgacggaa gtattgtatt
     6481 gatcgaactg acccattacc ctgaaaaagg gtatgcaact agtttagaag ggataatcaa
     6541 gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcgattg tcgtggctaa
     6601 cggtattcct acaaaatttc ctgatgatgt gttatctgag gcagatgaag ttccagacca
     6661 gatcagcgaa aaggatattg ttggacgcag agatttaaga gatcagctca tcgttacgat
     6721 tgatggagaa gatgcaaaag atctagatga tgcagtgacg gtcaaaaaat tagaaaatgg
     6781 taattatttt cttggagtac acattgcaga tgtatcttac tatgtgacgc aaggcagtca
     6841 actggacaga gaagcatacg aaagaggaac aagtgtctat ttgaccgatc gagtgattcc
     6901 gatgatccca caacgtttat ccaatggtat ctgttcattg aatccccatg ttccacgact
     6961 caccatgagt tgtgaaatgg agatcgatcc aaatggacaa gttgtctctc atgagatttt
     7021 tccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc aaatcttaga
     7081 agatcaagat gaagaaacga tgcaacgtta tgctcagctc gtgcctatgt tccaagaaat
     7141 gggtgaattg catcgaatcc ttgaaatgat gcgaatcaaa cgtggagcga tttcttttga
     7201 ggatcgtgaa gcgaagatcc ttgttgatgc tgaaggacac ccaaatgata tccagctaag
     7261 aagcagaggg ataggtgaac gcttgatcga atcctttatg cttgctgcca acgaaacggt
     7321 agctgaacat tataataaat taaatcttcc gtttatttat cgaatccatg aacagccaaa
     7381 agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc tggtccgagg
     7441 aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag tagaagacaa
     7501 accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag cacgctattc
     7561 agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact ttacatctcc
     7621 tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca gtgaagataa
     7681 aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag atcatagttc
     7741 taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga agaaagcaga
     7801 attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg ttgtgaaatt
     7861 cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca atgaattgaa
     7921 acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa gaactggtct
     7981 gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc cagatgaacg
     8041 agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac gtccaaaagc
     8101 acgcaatgga aaatctggaa aacgagaagg aaaacaagca ggcaaacgct cagaaaaaaa
     8161 tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga aaaaagggaa
     8221 aaagccattt tacaaaggtg tcaaaaagaa gaaaaagaaa aaataaaatg agttggagga
     8281 aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag ctcgccatga
     8341 ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg agatcaagtc
     8401 gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca acggggaagc
     8461 tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta atcatgatcc
     8521 gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg aaaacgaatt
     8581 gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg gctatgccaa
     8641 ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag atttgaaacg
     8701 aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat aatttcatta
     8761 tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg ttagcattta
     8821 atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg tgcatgggga
     8881 aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga aaatgttttg
     8941 aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg aaaaaaccag
     9001 atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat ggattggatg
     9061 aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt tgtataatgg
     9121 tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga aatcttaagt
     9181 tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt cgaggaatcg
     9241 taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca tttacattgt
     9301 ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc ttacctaacg
     9361 aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact ttggcattta
     9421 taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa ggatatttcg
     9481 taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt gaagaattta
     9541 caaacttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg gaagttttgc
     9601 taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca ttagcaattc
     9661 cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa gcatttgtct
     9721 ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa taatactcgg
     9781 ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa ttatatcgca
     9841 gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg tcaagttatc
     9901 tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt ccgtacaaca
     9961 atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt tatcgccttg
    10021 attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat cgtttgttac
    10081 tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc tatgctgaat
    10141 caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt tgtcagcggc
    10201 tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat cagcgatatt
    10261 ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca atctcgcatc
    10321 aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg ttctgatgca
    10381 gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa tattttgaag
    10441 gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat cactgtagaa
    10501 cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct tcaaatcgcg
    10561 gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat caatcaatac
    10621 attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa gacgttacgg
    10681 gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct atcaagatct
    10741 cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt taagtgatgt
    10801 tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg gttatgatgg
    10861 aatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg accttttgtt
    10921 catgattgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat tgggaagtgt
    10981 cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga atgttgcaaa
    11041 aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta ttattggtgg
    11101 cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc aattagaaaa
    11161 aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg gccatcaaag
    11221 cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac gtgctttcag
    11281 tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca catggtttag
    11341 aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga atggcgcaaa
    11401 acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc attcgtgaag
    11461 gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag gccttgatcg
    11521 gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc gttactgaca
    11581 aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct gttaacgaac
    11641 caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc ggacaacgtg
    11701 aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgattgat acgatcatca
    11761 accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa gattctacag
    11821 ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca atcgttgtga
    11881 atgccggtgc gtctcaacca gcaccattac tttatatcgc accatatgct ggtactgcaa
    11941 tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat gatctttcaa
    12001 aacaagctgt tgcttatcgt gaactttcct tgctacttcg ccgtccacca ggtcgtgaag
    12061 cttatcctgg ggatgttttc tacttgcact cacgtttatt agaacgtgca gcaaaattaa
    12121 gtgatgatct aggcggcggt tcaatgactg ctttgccatt tgttgaaaca caagctggag
    12181 atatctctgc ttatatccca acaaacgtta tctcaatcac tgacggacaa atcttcttag
    12241 aaagcgactt gttctacgcg ggtactcgtc cagcggttga tgccggacta tctgtctctc
    12301 gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact ttacgtctag
    12361 acttagcaag ttatcgtgaa ttagaagcat ttacacaatt cggttctgat ttggatgcgg
    12421 caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa caaaaactgc
    12481 atgcaccgct agctgttgag aaacaagtag tgattttgta tgccttgaca catggattct
    12541 tggacagtat ccctgtagac agtattttag acttcgaaca tgaattattc gaatatctgg
    12601 ataccaatca ttcagatatt tttgaaacaa tccgtacaac aaaagatctt ccagaagaag
    12661 aaacgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca aaaggaaata
    12721 attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt gagatgaatg
    12781 ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac gagccaaatc
    12841 acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc ttcttcacag
    12901 aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac tgctactcag
    12961 ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag catgctgctc
    13021 agccgtcctg tgaagaaaac cggttatatc gtcatcactg cagatggcgg tctggtcggt
    13081 ggatataaca gttcgatatt gaaacaaacg atgtctattt tagaagaaga ccaccaatca
    13141 cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt taaagcacgc
    13201 ggtatcaacc tagcatatga gctgcgcaat ttatctgatc agccaagctt tgatgaagtc
    13261 cgcaaaatcg taaatatggc aacaactatg taccaaaacg aagtattcga tgaattatac
    13321 gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga aaaaatgctg
    13381 ccaatctcag acttagatcc agaagaagca acgactttcg aacaagaata tatttttgaa
    13441 ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag tttgatctac
    13501 ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc aatgaaaaca
    13561 gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttataa ccgtgcaaga
    13621 caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc actagaatag
    13681 tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa tcggtcccgt
    13741 tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg cattagttgt
    13801 ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag aattagggga
    13861 cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag gaatggaagt
    13921 cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag gtcgcgtatt
    13981 caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg cggaaagaag
    14041 cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag aaattttgga
    14101 aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga aagtcggact
    14161 attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc ataatatcgc
    14221 ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc gtgaaggtaa
    14281 tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca tggtgttcgg
    14341 acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt tgacgattgc
    14401 ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca acattttccg
    14461 tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt ctgcggttgg
    14521 ttatcaacca acattggcaa cagaaatggg tcaattgcaa gaacgtatca catctacgaa
    14581 aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact acactgaccc
    14641 ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac gtaaattaac
    14701 agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg ctttagcacc
    14761 tgaaatcgtg ggagaagaac attataaagt agcaacagaa gtccaacacg tattgcaacg
    14821 atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat ccgatcaaga
    14881 aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa actttaacgt
    14941 ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa cagtgaaagg
    15001 attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt tccgaagtgt
    15061 tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga aaggggtgcc
    15121 ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc tatgatcacc
    15181 atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg cctaaacatg
    15241 caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca gattcagata
    15301 cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat aatgttgttt
    15361 caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt gcggaacgtg
    15421 caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat acgaacgaat
    15481 tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta tctaagcact
    15541 cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag gttatgacag
    15601 aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca aatttttgtg
    15661 aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatca gaggttgtga
    15721 aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct catattttgc
    15781 cgttttttga gctaataccg agggtcagat gattgaacac cgtttatttg gaataaggga
    15841 ctgcgacaag acttttgtct cagtcccttt ttttgcatat ttttagcatt tatttcctaa
    15901 aaaatgtaag gggattccta tatttttaag tatacttgtt tttcctttta tacattttat
    15961 ggtattatca ttttattagt tattataaaa caatcgttag aaaggacgtc attatgcaag
    16021 tatacggaat tgatgcggtg cttcgaatcg tgagtcattt ggcgtttatc tacttagcct
    16081 tctggtcttt acgttcgtta cgcattgaaa cttttttcag accaatgcat aatacgcaaa
    16141 ttagaatggc aatcgtactt ttttcaattt ttttagggta cactgcaagt aattttttct
    16201 tagaagttat cgctttatgc cgaaatcttt tcgttagcct gtaaatttta aaaaaaggta
    16261 ctattttaaa agcaaggatg ttataataga aaagattttg agtaagtgta tgctcattgg
    16321 aattttttgg agggaacaac atggaagaga tcatcgtaag aggtggcaat caattaaatg
    16381 gaacagtaag aattgaagga gctaaaaatg ctgttttgcc tattttagct gctagtttgt
    16441 tagcagaaga aggtattacg acattagaca acgttccgat tctttctgat gtcttcacta
    16501 tgaatcaagt gattcgtcac ttaaacgtag atgtagattt tgatgaacaa aagaatcaag
    16561 taacaatcga cgcttcaaga caattagaaa tcgaagcgcc ttatgagtat gttagtcaaa
    16621 tgcgtgcttc aatcgttgtg atgggtccgc tacttgccag aaatggacat gcaaaagtag
    16681 ctatgcctgg tggatgtgcg attggtaaac gaccaatcga tttgcattta aaaggatttc
    16741 aagctttagg agcaaaaatt attcaaaaaa acggctatat cgaagcaatt gcggatgaat
    16801 tgatcggtaa cacgatttat ttagatttcc ctagtgtggg tgctactcaa aatatcatga
    16861 tggctgccgt aaaagcaaaa ggaacaacca tcattgaaaa cgtagctcgc gaaccagaaa
    16921 tcgttgattt agcaaacatt ttgaataaaa tgggcgctca agtctatgga gctggtactg
    16981 aaacaatgcg tattgaaggc gtggatcatt tacatgcagt caaccactca atcgtacaag
    17041 atcgtatcga agcaggtacc tttatggttg ctgctgcaat gacacaaggc aatgtgctga
    17101 ttgcagatgc tatctctgaa cataactgcc cattgatttc taaattgatc gaaatgggtg
    17161 cagaaatcat tgaagaagaa ggcggagtcc gtgtcatcgg accaaaacat atcttaccta
    17221 cagatgtaaa aacgatgcct catcctggtt tccctacaga tatgcaagct caaatgacag
    17281 ctatccaatt agttgcagaa ggtacaagtg tggtgactga aacagtgttt gaaaatcgtt
    17341 tccaacattt agaagagatg cgccgtatga acgctcatgt caaaatcgac ggaaatgtag
    17401 caatcatgga tggaaaccat gaattgcaag gtgcagaagt atatgcaaca gacttgcggg
    17461 cagcagcagc attagtttta gctggcttga aagcaaatgg aatcacacgt gtgcgtaact
    17521 tgaattatct agaccgtgga tattataatt tccatatcaa actacagcaa ttaggtgcag
    17581 acgtcgaacg tgtagacatg gatcaaactt ctgctgaaaa aacagcacaa acgattgctt
    17641 aaggaagtgg ctgaatgagt aaccaacgat atatcttatt aactttgata aagattttag
    17701 tggtgatctt attgcttatc cttctttttg tggccggaac gatgatcgga tatggtgtca
    17761 tcggtggcgg caatccattt aaagtattcc agccaagttt gtggattcat attcgagact
    17821 tttttcattg ataaataaga atcacagtgg ttctagtcga tatgaagtga gccatgaagc
    17881 agaacatgat aaaagaaaac agaagggaac gttgacgtta gtcgcgatcc ctttttttag
    17941 taaaagaaaa gaaggaatct aattgatgaa gaagatattg atttatttag ttagaggata
    18001 tcagcgcttt atttcgcctg catttccacc tagctgccgt tattacccaa cctgttccaa
    18061 ttatatgata aaagcaattc aaacccatgg tgcgctaaaa gggacggtaa tggggactgc
    18121 acggatctta cgctgtcatc cttttgtcaa aggcggtatc gattatgtac cattgacatt
    18181 ccgattaacg cgaaataaga aagataaaaa agaaccagat tataaaaagg ttgtgaaaaa
    18241 tacgggtagc actgagcgat aaagaaaaag aggaaattta ttgtcaaagt aacaactccg
    18301 caactactta tatgggggac aaaaaatgat cgaagaacta aacaagaaag atttaccatg
    18361 gtccttgtta ttagatgcag atcctgataa agaaaaagtt caagtatatg tttccagagg
    18421 gagtggctgg atatggaaag aaaaagaaaa aacaataggt gtactgatct atgtggcaag
    18481 ggaaaaagaa tacgaaatcg tcaatgtagc agtaacccca acgtatcaag gaaaggggat
    18541 tggcggaaaa ttacttgaga cagcttttca gaagctttca cagctagctt caaaccaaac
    18601 tcggatcatt atacgtactg gcactactag tagcgctgcg ttacacctct atcaaaaaat
    18661 gggctatgtg gagattggtc gagtcaaaga ctattttatc catcattaat ctgagcccat
    18721 ttttgaaaat ggagatcaat taagggatca agtgatttta gcaattcact tacctaaaaa
    18781 tagctttaac taataaactt tcaattcgag aaaatgcttt caaatgctaa atagatacat
    18841 tacaatagct ttagcaaaca aaaaggagaa tatttttatg ggaatattag tttttgattt
    18901 tggtggatcg gctgtcaaat atggttgttg ggatggcaaa gagattaaag gtaagggaca
    18961 atttgcaacg cctgaatctt gggaagaaat gaaaacgcaa ttatttcaag tttataaaaa
    19021 aatactcgtt tcttttgaag tcgaaggaat tggaatcagc tctcctggag tagtgaataa
    19081 tgagaaacag gtgattgagg gaatcagtgc gattccttat attcatggat ttaatatttt
    19141 ccgagatttg gaaactctgt ttcaactccc agtaacgatt gaaaatgacg ccaactgtgc
    19201 cggaatggct gaattttatg aaggtgctgc ccgtgattat caagatgttg cttttgttgt
    19261 ggcaggaact gggattggcg gggcgttgtt cacgaaagga caaataaata aaggggcaca
    19321 tctttacggt ggagaatttg ggttgatgtt cttagatggc gataagacat tcagtaaact
    19381 tggtacagcg gtacagatgg cttggcgtta ttgtgaacgc aaaggtctcg ataaaaatgc
    19441 ttataccgga aaagatgtct ttgaattagc agaaactgga gatgcaatag caaaagaaga
    19501 agttgagagt ttttatacgt atcttacaaa gggattattc agtattcaat tttcgtttga
    19561 tccagaagtg atcgtattag gcggcggggt ttctgcaaaa gaagggctca ttgatgagat
    19621 caaaagccga atgaagaagc tgacagaaca attcgatctg catgatttcg aaccgcagat
    19681 tttattatgt gagtacagaa acgatgctaa tcttgtaggt gcagcagcaa actatctcgc
    19741 tgtacgtcaa ggagagaatt aagagcttta gagaaggtgc agcttgcata aaagaagaga
    19801 atgaaatgaa taggagattt ttacctaagg aatgttttat ttgctgcagt atgataaaat
    19861 atctgagagg tgaaaatgat gtcaaaaaaa aataaagata ttgaagtgcg tatagaagaa
    19921 gtgaaaaaag atatcaaagg taagaattat gaagtcactc agttatttat agggaaaaaa
    19981 atgattggtg agatcttagc ctatgggcca aaagaatatg aaattttctt tggtgaagaa
    20041 gattttggaa aagaaaaaag tcttgaaaat gcgatagaaa cagtgattcg acactggaat
    20101 ctgcacgaat aaaaaaatat caaaaaaact ttcaataaag ggttgcaaaa atctggaaga
    20161 ttaggtatta taactaagtc aggttgatac aaacctttcg gaggagtagc gaagtggcta
    20221 aacgcgacgg actgtaaatc cgttccttag ggttcagtgg ttcgaatcca ctctcctcca
    20281 tttcattggg gtatagccaa gcggtaaggc aagggacttt gactccctca tgcgttggtt
    20341 cgaatccagc taccccagta t
//
LOCUS       DAIGSZ010000050        20286 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.050, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000050 DAIGSZ010000000
VERSION     DAIGSZ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.050"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            141..461
                     /locus_tag="NOB31_001966"
     CDS             141..461
                     /locus_tag="NOB31_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974168.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            913..1113
                     /locus_tag="NOB31_001967"
     CDS             913..1113
                     /locus_tag="NOB31_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0974169.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1260..4049
                     /locus_tag="NOB31_001968"
     CDS             1260..4049
                     /locus_tag="NOB31_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCI0974170.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4096..4623
                     /locus_tag="NOB31_001969"
     CDS             4096..4623
                     /locus_tag="NOB31_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HCI0974171.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4644..5834
                     /locus_tag="NOB31_001970"
     CDS             4644..5834
                     /locus_tag="NOB31_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI0974172.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5874..7172
                     /gene="asnS"
                     /locus_tag="NOB31_001971"
     CDS             5874..7172
                     /gene="asnS"
                     /locus_tag="NOB31_001971"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HCI0974173.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8225..8899
                     /locus_tag="NOB31_001972"
     CDS             8225..8899
                     /locus_tag="NOB31_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCI0974174.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8896..9237
                     /locus_tag="NOB31_001973"
     CDS             8896..9237
                     /locus_tag="NOB31_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974175.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            9267..9626
                     /locus_tag="NOB31_001974"
     CDS             9267..9626
                     /locus_tag="NOB31_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HCI0974176.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            10150..12231
                     /gene="cadA"
                     /locus_tag="NOB31_001975"
     CDS             10150..12231
                     /gene="cadA"
                     /locus_tag="NOB31_001975"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCI0974177.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            12542..14008
                     /locus_tag="NOB31_001976"
     CDS             12542..14008
                     /locus_tag="NOB31_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0974178.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            14623..15162
                     /locus_tag="NOB31_001977"
     CDS             14623..15162
                     /locus_tag="NOB31_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HCI0974179.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            15236..15676
                     /locus_tag="NOB31_001978"
     CDS             15236..15676
                     /locus_tag="NOB31_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HCI0974180.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            15689..15898
                     /gene="copZ"
                     /locus_tag="NOB31_001979"
     CDS             15689..15898
                     /gene="copZ"
                     /locus_tag="NOB31_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HCI0974181.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            15898..18084
                     /locus_tag="NOB31_001980"
     CDS             15898..18084
                     /locus_tag="NOB31_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HCI0974182.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            18104..20275
                     /gene="copB"
                     /locus_tag="NOB31_001981"
     CDS             18104..20275
                     /gene="copB"
                     /locus_tag="NOB31_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HCI0974183.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         6778 a         3527 c         4407 g         5574 t
ORIGIN      
        1 aaaaaagagg ttgtgacgtg gtcacgacct ctttttgacg attatgatac aaaaaacatc
       61 atttatgaac aaaatgtgaa taacgggcgt tcttgagata tgattttaat tgggaaaaac
      121 ttatcgataa ggaggtcttt atgaaaaaaa gactgttatg gtgtttgctg tttctatccc
      181 taagtttaac aagtcagcca gtttttgctg aagaaacaca gcggtctcct attacaggca
      241 cacgtctgta caaaaatgtt tatgtacaga caacagatct tgattctgcg attcctgaaa
      301 cagaagaacg gtctttgcag ccaagatttg gttacttttg gtactgtccg acctgtgatt
      361 atgaaagttg ctggcatttc ttacattcta cagctgcagc ttttgctttt actcatactc
      421 agaaatatga tggacatcat cctgttattt atgaggtata gatatgagca aaaaagaaaa
      481 actaatctcg ttgatcgtat tggtttgcct tgttcttctg gtaactgtca taggctatca
      541 gaaataccat gagaacatca gacctactaa agaatcttcc ccagcctcga ccgttgaaac
      601 agaaccgata agtagtcaga aagaataatt tttttagttt aaagaagaac atcagagcaa
      661 aaaaacacca actgaacaat atgtcgttta ttttaaaaaa agttcggttt ttcactttat
      721 gtaatcgctg agaaaacttt ttttaataaa aaaagtcgaa aaactctagc ttttttgtaa
      781 acggtatgat atactatagg agtagttttt gttcggtaat ctgtggtagc ttgtttcaaa
      841 taaacatctt ccagatatac accattcaag taattgcaaa atatgtgttg atacacaagg
      901 aggattttta ttatggaaac aggtacagta aaatggttta actcagaaaa aggatttgga
      961 ttcatcactg cagaaaacgg aaacgatgta ttcgttcatt tctcagctat ccaaggcgac
     1021 ggattcaaaa ctttagaaga aggccaagca gtaactttcg atgttgaaga aggccaacgc
     1081 ggacctcaag caacaaacgt tactaaagct taattaacct atactaaaaa ataaacgccc
     1141 agacatttgc gtgtctgggc gtttttgtct attttcttta aaaagcgatg agagtatttt
     1201 tctgcacttt gtagtataat ttcaaaagaa cattagaggc aggagaagag gaagatattt
     1261 tgaaaccaag aacttatgca gtcgttgata tcgaaacgac tgggacgaat ccaaaagaag
     1321 atcggatcat ccaatttggc tgcgtcatga ttgaatcagg tcggatcact tcacgttttt
     1381 cgatcgatat tcatccaggg cggaagattt caaaacaaat ccagcattta acagggatca
     1441 cgaatcaacg cgtccaaaaa gcgccttatt tcgaagatgt cgcccaaacg atttacaatc
     1501 ttttggcaga caccatattt gtcgcgcata atatttattt tgattataat tttttgaacc
     1561 atgaactcat gcgatgcgga cttcctagtt tgaagatacc aggcatcgat acagtagaac
     1621 ttgcacaaat tttcttgccg acggaaccaa gctttcgctt agctgatttg tcagaaagcc
     1681 ttggatttat tcatgagaat cctcatcagg cagatagtga tgccgaagtg acgggtcaac
     1741 ttcttttgct gatcgaagaa cggatgagaa aattgccaat catcacgtta gagcagattg
     1801 cgcgattaag tagacacaca ggtatggata cgagtcgttt catttatcat gtgattgaag
     1861 aaatgaaaga aaaaccagag ccacttgatc cctcattaga aatcgtcgat gggctagctt
     1921 tgcagaaaaa agaagtggaa ctattcacat ccgtccatta tggcgagcgg acatatccaa
     1981 gaaaaaaaca agcaaaagaa aaaatgtttg gtaaaacact gatgtatcga aaagaacaga
     2041 acagactgat gaatgcggtc tacgaccatt tcacaaaaga tgaatcaaaa gatttgatga
     2101 tcgaagcagc tacaggaatg ggtaaaacaa tcggttatct gctgccattg agttatttgg
     2161 ctacacctga aaaacccgct gtcatcagta ccgtttcgct agttttgcag cagcagatca
     2221 tagaaaaaga cattccattg ctgaatcaat tgctagatca gcccatacaa cctgtaatta
     2281 tcaaaagcta tcgccactat attgatttac agcgttttaa aggcacactt gtggaaccgc
     2341 cagaacaaaa acaatatgct ttgtatcaaa tggcggtctt agtttggctg acgcaaacga
     2401 agaccggtga tttggatgaa ttacatttaa caaatttgaa ccattcattc tttgcagata
     2461 tcgcgcacag aggtattgga tttttagcaa gaaatcagtc attttacgaa caagactttg
     2521 ttcgtttctt gcaaaagaaa atcaggcaaa gtaatttttt gattgtcaat catgcgtttt
     2581 taatacaaga aacacagcga aaagaaccat tgcttccagc tagtccattt ttgttgatcg
     2641 atgaagtaca tcatttgccg gaaatcgctg aaaaagtaaa tgacaaacga ttaagtatta
     2701 actatttcca taaacaaatc cagcaattag aagaaccaaa tcagctgttt gaccgaatac
     2761 aaagctattt accgaaagaa catgaagcct tacgctggtt atcgatttat cgagaagaac
     2821 tttctgcgct atgcgaagca cagatttgta tggcagaagg attaatgagt ttagtgagcg
     2881 gcaagcaacc taacggacag tatccagaag aagtcatgat gacaaaagag atgttggatc
     2941 agctgccact ggaatctggg acagccattg atcacctgca gcttttttat caggagatcc
     3001 agcagctaca gtcacaaatg cgtctgactt ttgagattat ccaagaaagc tggacaaacc
     3061 agatgcggat cgatttagca agtttatata gcttatttga tcaattagac aagcagtact
     3121 tgctgatgga tcaatggctg gaagactggc gagatcattt gatccattgg ttcgttcctg
     3181 ggaacacagc gcagcagatg atttttcatc tccatgattt tcaagcggct atgttgccgt
     3241 cgactgtttg gtatcctcga tatgatcgta ttctttatat tggaggaacg ctgaagatcg
     3301 gccctaatcg acactatctc tctaagcggc ttggcattga agcagcacct cttaaagtga
     3361 ttgcctctcc ttatgattat gagaaacagg caaggatcta tgtgccaaaa gaggcacctg
     3421 ccgtccatca agtcagcaat caagcatata tcgattattt agagacagca cttacaggtc
     3481 tgatcgaaca agaagatcgg ccaatacttg tgttattcac ttctcatgat gttttgcaga
     3541 aggtctatca gaaaatgcat ctgtctatgc tagaaaaagg acgagaaata ctagctcaag
     3601 ggtttggcgg aagccgggag aagcttttga aacgcttcat tttgtcagaa aaaagcgtat
     3661 tgtttggcgc tgacagcttt tgggaaggtg tagatttgcc tggggatgct ttgcagatcg
     3721 ttgtagtcac acgtttaccc ttcgataatc cgcttcgccc gatggtcaaa gctaggaacg
     3781 cttatttaga atcagagggg atcaatcctt tttaccagga atccgtacct aaagcagctt
     3841 tgaagttacg ccaagcatta ggtcgcttga taaggacgga gacagatcgt ggcgtattgc
     3901 ttattttgga tcgaagacta gtcactgcaa aatatggtgc acggatcatc catgcattac
     3961 cgaaaaaagt accgatcaaa gagctagcta tggaggaaat ctatcaggac atccatgaat
     4021 tcttaaagaa aaatgaagaa ggaagttaga ggagctgtct tttttcataa ttaaaatctg
     4081 ctataatgaa aaggaatgaa gataaaggag cgacgaccct tgaagaaaaa acagacaaag
     4141 gaaaaaacga ttaatcgcgt gttacttggc ttgatcgtat ttttattagc ggtcatcgtg
     4201 atcagctcga ttttttactt gcgttccagt cgtccggcgg tgcaggcgaa gaaagaagca
     4261 gtagaaatcg caaagaaata tgcaaatctt gaggaagccg atcattttta ttggtttact
     4321 cgaaagaaga catacttttc actgacaggt acaaatgata aaggaaaaga aatcgccgtt
     4381 atcattccta aatctggtga aaaagtaaaa gtattggatc aaacaaaggg actgactgaa
     4441 aacgaagcaa aacagacaat tgctgcggcc catcctgaaa tccaaatcga aaaagctgct
     4501 ttagggatgt atgatgatca gcctgtgtgg gaagtagtag gaaaagaaac aaatgggaaa
     4561 ctgaattatt acctgattgg ctttgaatct ggagatgaag tcaagacaat caagggaatt
     4621 taaaaggtaa aggaatgaat gggatggagt tatcaaaaag aacaaaacga ttagaaccgt
     4681 ctgtcacttt ggcagctgcg gcaaaggcca aggcattaaa agcaaaaggc agagatgtgc
     4741 tgagtttgac tgtgggagaa ccggattttg cgacaccaga aaacatccaa gaagcagcaa
     4801 tcgaagcaat ccgcaacggg aaagctagct attatacacc aacagcagga atcccagagc
     4861 ttcgacaggc aatcgttgat tatctgaaga aaaactatgg acttgtctat gaaccttcac
     4921 aaacagtcgt aacagacgga gcgaaatttg ctttgtatac ccttttccaa acgatccttg
     4981 acccgcaaga tgaagtcatc attcctgtgc cttactgggt cagttacggt gagcaagtaa
     5041 aactggcaga aggacttcct gtctttgtga aaggggaaga atccaatagc tggaaagtta
     5101 ctgttgaaca gctagaacaa gcacgttcag aaaaaacaaa agccgtaatc atcaattctc
     5161 catcgaatcc gactggaatg atttatagca agaatgaact gcaggcaatc ggtgaatggg
     5221 cagtaaaaaa tgatattttg atagttgctg atgatattta tggtcgttta gtttataatg
     5281 gcaatgagtt tactccaatt gcaacgattt cagaagcaat caaaaatcag actatcatca
     5341 tcaacggcgt gtctaaaaca tatgcgatga caggctggcg cattggttat gcggtgggaa
     5401 atcctgtgat catcaatgga atgatcgctg ttgcttccca gtcaaccagt aatccgacag
     5461 cagtcagtca atatgcagct gttgaagcat tgaaaggcga gcaagataca gtggaagaaa
     5521 tgcggaacgc ctttgaagaa cgcctgaata cgttatattc gcttgtggca gaactgccgg
     5581 gtgtttctct tgaaaagcca caaggagctt tttatctttt tcctaatgta aaagaaacgc
     5641 tacgcatgtg taaatatgaa aatgtcacac aatgggtaga agatctttta gaagaaacag
     5701 gggtagcgct tgtgactggc gaaggctttg gggcaccaga aaatgtccgc atgagttatg
     5761 ctactgatcg cgctacgtta gaagaagcgg tacgcagaat caagcaattt attgagagta
     5821 aaagtcaaaa ttaatcctaa agaaattcaa ggaatataaa aggagagtca tacgtggaac
     5881 aaattcaaat catcgattcg aaaaaccatg tgggagaaac agtaacaatc ggcgcttggg
     5941 tcgcaaataa gcgatcaagc ggaaaaatcg catttttaca attaagagac ggaacagcct
     6001 ttttccaagg tgtagttgta aaaagcgaag tgtcggaaga agttttccaa acagctaaaa
     6061 atctacacca agaaacatcc gtgttagtaa ctggagaaat ccgtgaagac agtcgttcaa
     6121 aatttggtta tgaaatcgga attacaaatg tggaagtggt aagcgagagc cacgattatc
     6181 cgatcacacc aaaagaacac ggaacagact tcttgatgga tcatcgtcat ttatggctgc
     6241 gttcttcaag acaacatgcg attatgcaga tcagaaatga aatcattcgt gcaacgtatg
     6301 aattctttaa tcaacatcat tttgtcaaaa ttgatccgcc gatcttgact ggttctgcac
     6361 cagaaggcac tacggatcta ttcgaaacaa attactttga tcaaaaagct tatttatctc
     6421 aaagtggcca attatacatg gaagctgctg ctatggcttt cggaaaagtc ttttcattcg
     6481 gtccgacttt ccgtgctgaa aaatcaaaaa cacgacgtca tttgatcgaa ttctggatga
     6541 tcgaaccaga aatggctttc actcatcaag aagaaagttt agaagtacag gaacaatatg
     6601 tagcattctt agtacaaaat gttttagatc attgcgaata tgcattagat gtactaggac
     6661 gagacaaaga agtcttaaaa acttatacaa aattgccatt ccctcgtatt acttatgatg
     6721 atgcgatcga attactgaag aaaaatggat ttgatgacat cgaatggggc gaagactttg
     6781 gttcacctca tgaaacgttc attgcgaatt cattcgaaca gcctgtcttt atcctaaact
     6841 atccaaaagc catcaagcca ttctacatga aaccacatcc aacaagagaa gacgtggtga
     6901 tctgtgcaga tatgatcgca ccagaaggtt acggtgaaat tattggcgga agcgaacggg
     6961 caacagacta tgatttcttg ctagaacaaa tccgtaatca cggtttggat gaaaaagaat
     7021 attcatggta tcttgatcta cgtaaatacg gttctgttcc gcactctggt tttggtctag
     7081 gtcttgaacg aacagtcact tggattgctg gtatcgacca tgtacgtgaa gctattccat
     7141 tcccacgttt gttgaaccga atttatccat aagaggtgat gaaaaagctg ttctgcatca
     7201 agtaattaga acagccaagc aaaaacagct gttcatgttt ttgaattggc gggacttatt
     7261 accgcagatg taagcttttg aataccgttt agtggagagg ttgtgaaaaa gctgtttagt
     7321 ttcgagtatt aagaaaaatt ttgtggaaat ggctttccac atttttgcat aaatttggct
     7381 taataccgag aaactggctt ttgaacaccg tttaaggaag aggttgtgcg cctgccgttc
     7441 agctccgagt cacaaggagt aatttcaaaa aacagttttt catgtttgat gactattgtg
     7501 acttgtgacc gaggagttgg ccggagagca ccgtttattc taaaaaagaa ctgcgaactc
     7561 tcgcagttct ttttttaaaa tacgggataa aggaagtttc cagcagacaa gagaagaaag
     7621 caaaagaaat tgctatttga ttcacaaggt tctataacga aatcgcaatc aatcaaacat
     7681 ttacaaagaa ggtaattcaa atggaaatct gatttgatga tgcttctgct gttgaaataa
     7741 agcagcatct agcacctgaa aacaaactaa tagtaacatt cgaagatgga gtaggtccgt
     7801 attttcagca tgcaataatc catatgtaag ttcaattcac ccttgaaatc atcggaccag
     7861 ataaagttat gaccaatcta tcccaagcaa tctagaagag atattagtaa agggacattt
     7921 actagaagtc ttagatgagc ctataaatat atgttctgat ggcgtcatca gtggtctgat
     7981 tgacggaagc ttaggtgtga tcgatctctc tggaccaaac aacgaaggaa tcaaggggaa
     8041 tccggcacgt taagaaaaaa atagcataaa aaactagaca cttgatgagc gttcattcaa
     8101 ttgtttgaag ggactaggct ggtgtcattt tttatacata tattttctct ttcgtcttga
     8161 tagggcttat gggataatat aaggaagaaa atcatcgttt tattcaaaaa ggagtttttg
     8221 acaaatgaaa aaacgtatat tatttatcgg tgatagcatt acagacgcag gaagagaccg
     8281 agcagaagca actgatctag gtaaaggtta tccacttttg attgccggaa aactaatctc
     8341 ccaatatcca acgatggaat ttgaatgcat gaaccgtggg ataggaggag acaaaattgc
     8401 agatctgcaa gtacgctggc aagaagattg tttagcttta caacctgact atgtatcgat
     8461 tttgatcgga atcaatgata cctggcataa tactagcgat caggctatat tcggaactga
     8521 gaaatctgct cagcaatttg aatccgttta tcgaaaatta ctaaatgaac ttcaaacagt
     8581 gggaatctgc aacatcatct tgatggagcc gtttgtactt cctataaccg acgaccgtca
     8641 tggctggcgt aaagacttag accctaaaat ccaaattgtt cgtaaacttg ctaaggaata
     8701 tggcgcattg ctggttcctt tagatggtat attcaatgct ttagggattg tttatggttt
     8761 ttcgaaatat acaagagaag atggggtcca cccaacgatt ggcggacatg agatcattgc
     8821 acaaagctgg atagatgcaa ttgccgcagt cgattttttt agtggagata aaaatgagcg
     8881 aaagaaaagt gagaaatgat ggaaatacgg tgggcagtaa aagaagatct acctcaaatc
     8941 aatcagctga ttactgatca tccagaatca ttcgtaaaag caaaaacggc agctgaccta
     9001 aatgataaga ataaactatt gctcgttgct gtaacaaaag aaaaacggat tatcggattt
     9061 gcgcaagcgg acgtgcaaca gtcagaagaa cgattggatc agcgaccatc aggaaaacta
     9121 atccaacaca cattagtaac aaaagaaaat acggaagaaa tccaaaaaaa atttgcagaa
     9181 tatttgatac tggaagctaa aaaaagaaga ataaaatcat tttttgccca gttttaatca
     9241 aaaacagtaa tagaaggaga aatacaatga gttgtttagg aaatgtcatc tggtttatat
     9301 tcggcggact aatcggtggt cttagctggt tagcagcggg gatactttgg tgtatcacga
     9361 tcataggtat cccaatcggt atgcaatgtt ttaagatcgc ctccctttct tttgcgcctt
     9421 ttggcaaaga agtaatttat caccagtctg gcatgtcatt gattgttaat atcatctggc
     9481 tgatcgtttc aggcctacca attgctctcg cacatgtcgt cagcggcatc cttctatgta
     9541 tcacgatcat agggatacct tttgccaagc aatctttcaa acttgctcga ttggcgttga
     9601 tgccattcgg tgcagaaatt gtataaaaga gaataataaa ggttagataa agcatagagt
     9661 caggtgggat acatgtattt cacctgactc tatgcgttct cctgtataag ttcttccatg
     9721 tgacttttac gtcttttatt tatatggggt tactgtttat ggaaagttga aataattttc
     9781 attaaagaac tctttctata tttttgaaag cgtagtggag cttcgaatat ctgggaagga
     9841 cattttgcag ggattgaaaa aagatattgt cctatcgaaa aattaatgaa tttagacaaa
     9901 ttgccagcaa caggcttcaa acttagttgc tatcctgtca agatcaagaa ggcaagtgcg
     9961 ggttggataa gagcagtggc aatgatcgaa aagaaaaaga aagaataagc caaaacatct
    10021 gtatggaaga aattttccga tgcagatgtt tttcattttt tctttcggat accttgacat
    10081 atgaataacc gttcatttat aattagttat gaagagatat tcatatgttg aggcgaggag
    10141 gtcattaaaa tgaaaagtta cagattagaa ggtttagatt gtgcgaactg tgcaatgaaa
    10201 atcgaaaaag gagttcagaa gatcaatgga gtcaaggaag caacggtaaa cttcacttct
    10261 ggaaaactaa cgattgacgc agaggaagat catttggcta cgattgaaca agaaataaaa
    10321 aaagtagtga aggaattaga accagatgtc aaagtaacag aaatagataa ggaaaaagta
    10381 tctgaacatg gaaatgaaaa agagagaaat acgctgttcc ggattttatt ttcccttgca
    10441 ggtatcgctt tattgctatt atttgatttt aatgaaccaa ttcgcttgat agggtattta
    10501 ttgatttatc tgctgatagg atatgatgta gtgaagaagg cagtgatgaa tatcgtcaaa
    10561 ggaaaaatct ttgatgagaa ttttcttatg tctgttgcta cgattggcgc tatgttgatc
    10621 ggtgaatatc cagaagccgt agcagtgatg ctattttatc aaatcggcga gtatttccaa
    10681 ggattggcag tcagtcattc aagaaaatcg attcgcgaat tgatggcgat ccgtccagaa
    10741 acagctcacg tgcagacgac ggaaggattg atgaccgtga accctgaaga cgtgcagatc
    10801 ggtcagtttg tacttgtgaa gcctggtgaa cgtgtaccgt tagatggaac gatcatcgaa
    10861 ggagaatcat tagtcgatac gtcagcactt acaggagaat cagtccctaa atctgtatat
    10921 gttggtgaaa cagtattaag tggatttatc aataaaaata aaccattttt agttcaagta
    10981 gaaaaatctt atgaaaattc tactatcagc aaattattag aattagtaga aaatgccagc
    11041 agtaaaaaag caccagctga aaatttcatt actaaattcg cgcgctatta cacaccagtc
    11101 gttgtaggat tggccgtttt attagctgtt ttacctccac ttgttgtttc tggagcggcg
    11161 ttttctgaat ggatctatcg agcattgaca tttttagtga tctcatgtcc atgtgcatta
    11221 gtgatctccg taccccttag tttctttggc ggtatcggag gagcaagtaa aatcggtgta
    11281 ttagtaaaag gttcaaatta cttggagttg cttgcacaaa ctgagacagt ggtattcgat
    11341 aaaaccggca cattaacgaa aggtgacttt tcgatccaga cgatcgatac aaaaatcgat
    11401 ccaaagatat tcatgcaata tgttgcgagt gcagaacagt tttctacaca tccgattgct
    11461 caatctgttt tagaaggcta cgcaggtccg cttttaccaa cagctaatat ccaagaattt
    11521 gcaggtgaag ggatcttagc tgaagttgat ggcaaacaag tattagcagg taatcacaaa
    11581 ttgatggaaa gatttgaaat ctcttttcct tcaagtcaag aaatcggtac attgctttat
    11641 ctagcgatcg atcaaagtta cagtggttat cttgttattg cagatacctt gaaagaagat
    11701 gccgtagacg cattggttca attaaaaaag gctggtgtga agaacacagt catgttgacg
    11761 ggcgattcga aaaaaattgc tgatcatatc gggaagcaag taggcgtgga caagatatat
    11821 agcgaattgc ttccagaaga taaagtgcag cggttagagg aaatcttaca aagaaacaat
    11881 aaaaagaccg catttgtcgg agatggaatc aacgatgcac cggtgctagc aagagcagat
    11941 gtaggaatcg caatgggtgg attgggaagc gatgctgcaa ttgaagcagc agatgtagtc
    12001 atcatgaatg atcaaccatc gaagattgca gaagcaatcc atttagcaaa gaaaacattg
    12061 aaaatcgtca aacagaacat tgtctttgct attgggataa aaattttggt acttgcctta
    12121 ggtgcttttg gttttgcatc aatgggagat gcagtatttg cagatgttgg ggtgacagta
    12181 ttagctgttt tgaatgccat gcgaagcttg catgtaaaaa ataaacgttg atcaatgaag
    12241 aggacgaatg aacgtcctct tttttttata tccttttctt aatgaaaaat gtaaagaaaa
    12301 tagataggat tataaaataa ctaatgtttt taattttgca gaaaattcaa aatagcttga
    12361 aattcaataa ggtaaatgaa ataaaagaaa ataacttatt tttttgatgg aaaaaatatg
    12421 aaaaaacgat gtgtattaaa taaaagaata cacacataaa ataacactgt cttgtaagtt
    12481 tgttaaaaat tgaatatgat tacatctgga taacaaattt ttatcataaa ggagagaacg
    12541 aatgaacaac aaacaattac gctggtttac tgttgcgtta attgcattta acatggtttg
    12601 gggcatgggg aatgtagtta ataactatgc tcagcaagga gtatcagttg tcacctcttg
    12661 gctattgatt ttggccattt attttattcc atacgcattg atcgttggac aattagggtc
    12721 agccttcaag gatagtaaag gaggcgtcag ttcatgggtc gaaaatacga catctaataa
    12781 acgactggca tactatgccg cttggactta ctgggtcgtc catattcctt atttggcaca
    12841 aaagcctcaa gcaatcctga ttgctggcgg ttgggcagtc caaggaaatg gaaatatcgt
    12901 aaatacgatg tcagtacaaa tggtagcagt tatttcactt attatatttc ttgccttttt
    12961 atatttatca acaaaaggac tttctacttt gaaagtgatt ggcggactgg ccggaacagc
    13021 gatgttcgtc atgtcgatct tatttattct tttagctgta acggcaccgt tcatcaatcc
    13081 aacgatggaa tttgccacac cacatatgaa tcaagtgaaa acatatattc caacatttga
    13141 tttcagttat ttcacaaccg tttcgatgct agtatttgca gttggaggag cggaaaaaat
    13201 atccccttat gtcaactcta caagaaatcc tgcaaaggaa tttcctaaag ggatgatctt
    13261 cttagcagca atggtaggga tttgtgctgt attaggctca gtcgcaatgg gtatgctgtt
    13321 tgctagcgat aatattccta aagacttgat ggcaaatggg gcatacagtg cttttcaaat
    13381 tttaggtaat tactatggta tcggtaactc attgatgatc atttacgcat tgacaaacat
    13441 gattggacaa atctccgcat tagccttttc aattgatgca ccactaaaaa tcttgttagc
    13501 agatgcggat ccagaatttg taccaaactg gctacgtaaa cgtaatcgta aaggtacatt
    13561 ggtgaatggt tatcttctga caggtatact agtaggaatc attattttgt tgccgatctt
    13621 tggtatcaaa gatatgaatg aattagtaaa atggttgacg aacttgaact cagttgtcat
    13681 gccaatgcgt tacctatggg tgttcttggc atatatgatg ttgaataaag cttataagaa
    13741 attcaattct gaatataaat ttgttaaaaa tccaaaaatc ggttttatct ttggtgcttg
    13801 gtgctttgcc ttcactgcgt ttgcatgtat cctaggaatg gtgccaaaag tagattatac
    13861 tgctgatcct aaagcatggt ggttccaatt attcacgaat atcatcacac caattgtctt
    13921 gatcttatta ggtatgatct tgccagcaat tgctcgtcga gacaaaaaca aagaaatcac
    13981 tgaaccagaa acagtggttc agccttaaaa tagaaatact tgttacaaga ggttgtgaca
    14041 gaagtggtca gcttcaagaa ataagaagga atttacgaaa attgcttctc aaatttttgt
    14101 gaagtttcgg cttgtttttc gcagaagcta cttctggaac accgtgaatc agaggttgtg
    14161 aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagccc ctcatatttt
    14221 tcgttttgct gggcttatta ccgcagatgc aagcttttga acaccgttta agaaagaggt
    14281 agtgagcctg ccgtttaact ccgagtcaca aggagcaatt tcaaaaaaca acttctcatg
    14341 tttgttgact attgtgcctt gtgaccgagg tgttggcagg agaacaccgt ttaaggaaga
    14401 ggttgtaaaa tcagcgattt gacctgagta ttagaggaac aaacgaaaaa atagctcctc
    14461 atattttgcc gttttttgag ttaatgctga aggtcagctg attgaacacc atttattcga
    14521 aacaagggac tttgacacga cttttgtcac agtcccttgt ttttttgcgg cgttataagt
    14581 ggtatgatcg aaccaaattc caaagagaag tgagggagaa gaatgaagat catcgtgatt
    14641 ggacaaagtg ggtcgggaaa atcgaccctc gcaaggaaga tcaaagaaat caccgacttt
    14701 ccgctactgc cgctagacct tttatggcat acaacagact acagtattca ggcaaaaaag
    14761 tggtttttgc aagaacagca atcgtttatg gtatctaatc cgtcatggat tgttgaagga
    14821 aattatactt ctacattaga ggaaaggatt aaagaagcag ataagatcat ttggcttaaa
    14881 gtgccgcgtt atctcgccat ctaccgagta gtttggcgtt ctctaaaaag aaagataaac
    14941 aaaaaatctc ggccagatat gcctgaatca ttttcagaga aactaaacag ggaatactta
    15001 gaatttttat cttttatctg gcattttgaa gaaaacaatg aaccgaaaat acagcagctg
    15061 atccaagtag ctaatgcaag aaataaactg atcatcctta aaacaagacg agagaaacaa
    15121 gaatttttaa ctaaattgaa aatagagagc aaaaataatt gacagttttt gtttacaagc
    15181 gtaatctgta ttcataagct aatgattaca tttgtaaacg aaaggtgtga aataaatgga
    15241 aaaagtcaaa acgccagtaa agatcagtga ttcagagtgg gagatcatgc gtgttatttg
    15301 gacacttgga cagacgacag cccaagaaat cacgcagatc ttagctgatt cgatggattg
    15361 gaaaccagca acgatcaaaa ctttgctggg acgtttggta aaaaaagaag tgatctggac
    15421 agaacaagaa ggaaaaaaat tcatttatca tccagctgtc tcggagatgg aaacagttcg
    15481 cagtgcgacg gaaaatcttt tttcccatat ctgtgcaaaa aggattggag agacgattgc
    15541 ggatctagta gaagaagcca ctttgactca agaagatatc aatgagattt tgaaacaact
    15601 ggaacaaaag caaccagtag atacgatcga atgtaactgt atcccaggtc aatgtgaatg
    15661 taaacaacat caataggagg aagaaaaaat gaaacaacaa ttttcaatcg aaggtatgag
    15721 ctgcaatcat tgtgcagcaa gagtagaaga aacagtaagc gcacttgacg gcgtgcaaaa
    15781 agtgaaagta aatttgaaaa aagcaaacgg tacggtcaag tttgatgaaa caaaagttca
    15841 atccgaaaag atttgtcaag caatcaatgg attgggttat aaagcagagg tgatttgatg
    15901 gcaacagcag aaaccaaaat ggatacgttc gtcattacag gtatgacttg tgcaaattgt
    15961 tctgctagga tcgaaaaaga gctgaacgga caacctggtg tggtcaatgc cacagtcaac
    16021 ttggccactg aaaaagcaag tgtcaaatat gaagggacga ccactgaaaa attaatccaa
    16081 agcgtagaaa acatcggtta tggtgcaatt ttgtacgatg aagcccacaa acaaaaaatt
    16141 gcagaagaaa agcaagcgta tttgaaaaaa atgctattcg atcttatatt gagtacggtt
    16201 ttgactttgc cgttgatgtt gtcaatgatt gctatgatgt taggaagcca tgcggcgatt
    16261 gttcactttt ttcattttcc aatcgtccag ttagtgctgt ctgctcctgt ccaattttat
    16321 gtcggtgctc gtttttataa aggtgcgtac catgcaatca agacgaaagc accaaatatg
    16381 gatgtattgg tagcaattgg aacatcggct gcctttgcat tgagcattta caacggattt
    16441 ttccgtggac acccccaaga tctttatttt gaaagcagca gtatgatcat cacgctgatt
    16501 ttgctcggca aatatttgga acatacagca aaaacgaaaa caggtaatgc aatcaaacaa
    16561 ttgatgtctc ttcaaacaaa aaccgcccaa gtgataagaa acgggaaaga agaaacgtta
    16621 gcgattgaag aagtagtcgt tggtgatcaa ctagtcatcc gtcctggtga gcagattcca
    16681 gcagatggtc gaattatttc aggaagcagt gcgatagatg aaagtatgct tactggtgaa
    16741 aatcttcctg tagaaaagaa tccggatgac acgctttttg gcgggacaat caatacgaat
    16801 ggtctgctac acatggaagt cacacaagtc ggcaagcaga cagtattagc gcaaatcatt
    16861 caaatggtgg aagatgctca agggagcaaa gccccaatcc aaaaaatcgc agatcggatc
    16921 tcagggattt ttgttccgat cgtattagtc atcgcgttta tcacgctcat agctacaggt
    16981 ttgatcactg gtgattggca actcgcattg atccatagtg tctctgtatt agtcattgcg
    17041 tgtccatgtg cattaggttt agcgacccca acagctatta tggtaggaac gggtgttggt
    17101 gcacgaaatg gaattttaat taaaggcgga gaagcattag aagcagctgc tcacttagac
    17161 agcattgttt tggataaaac tggaacgatt acagaaggaa agcccaaagt tacagatcta
    17221 gtcggttcaa aagaagtcct atctattttt tatactttag aacaagcttc tgaacatcca
    17281 ctaggtaaag caatcgtgga atacggaaaa ctgcaagaag cagcaacata cgatatgatt
    17341 gattttacag cccacccagg tgctgggatc agcggtacga ttaatggagt acgctatttt
    17401 gcgggtacac gtaaacgatt aattgaattg aacctatcat ttgatgaata ccaagaacac
    17461 gcgttagaat tagaacagca gggaaaaaca gtcatgtttt tagctgatga aaagcaagtg
    17521 atcgggtgga ttgccgtggc tgatcaaatc aaactagaag ccaaacaagc aatcaagcag
    17581 ctccagaata aaggattaga tgtttttatg ctgacaggag acaacaaact ggcagccgaa
    17641 acgattggta aacaagttgg tattgatcca aagcatatct ttgctgaagt acttccagag
    17701 gataaagcag cctacgtaga aaaacttcag aaagatggca aaaaagtcgg tatggcaggc
    17761 gatggaatca atgatgcacc ggccttagca ttagctgatg tcggtatggc aatgggaagt
    17821 ggaacggaca ttgcgatgga aacagccgat gtgacgctga tgaatagcag tttggcatcc
    17881 attgcacaaa caatcgagtt gtctaggttg acattgagaa aaatcaaaca aaatcttttc
    17941 tgggcttttg tctataatac gattggtatt ccttttgccg cactaggctt tttgaatcca
    18001 atcattgcag gaggagcgat ggcgtttagt tccgtcagtg tattgttgaa ctccctgagc
    18061 ttaaatcgac acatgaaaaa gtaagagaag ggatggagta aaaatgaatg ggaacgatat
    18121 ggagaaaaaa catgagcata aaaaagaagt agtaaacaaa gaaagtacag aatctcatga
    18181 aaaacagatg gagatgaaac atgaccatag tcagatggat cattccatgc acatgggaca
    18241 taaccatgga gatatagcaa acagcaaaca aatggaccat tcgatgcaca tggatcacga
    18301 acacggcggc atggatcatt ccatgcacat ggggaatttc aaacaaaaat tttggctatc
    18361 gcttatccta gctatcccaa tcattctttt ttcaccaatg atgggaatgg aatttccatt
    18421 tcaagtaacg tttcctggtt ctgattggct cgtattgatc ttagcaacta tactatttat
    18481 ctatggcggt cagccatttt taagtggagc taagatggaa ttgaaacaaa aaagtcctgc
    18541 tatgatgaca ctgatcgcga tggggattac agttgcatat atttatagtg tctattcgtt
    18601 tatcgcaaat ctgctcaatc cacatacaca cgtcatggat ttcttctggg aattggctac
    18661 tttgatcgtt attatgctac taggtcactg gattgaaatg aatgctgtgt cgaatgccag
    18721 caatgcttta caaaaactag cagaattact gccagaatca gtgaaacgct tgacgaaaga
    18781 tggaaaagaa gagacagttt cattgaaaga agtaaacgaa ggtgatcgtt tgatcgtccg
    18841 gtctggtgat aaaatgccaa cagatggtgt aatcttgaaa ggtgaaacaa ttgttgacga
    18901 atcagctgtg actggcgaat caagaggaat caaaaaacaa gccaatgaca aagtgattgg
    18961 cggttctatc aatggggatg gaacgatcga aatcgaagta actggaactg gtgaaaatgg
    19021 ttatctagcg aaggttatgg aaatggtgcg aaaagcacaa ggagaaaaat ccaagctaga
    19081 gtcattatct gacaaagtgg caaaatggct gttttatgtc gcattaattg tgggtatcct
    19141 ggcattcatc gcctggttgt tcttgacaga tcttcctaat gcattagaac gtatggtaac
    19201 agtctttatc atcgcctgtc ctcatgctct aggtttagct atcccattag ttgttgctcg
    19261 ctccacatca atagcagcta aaaacggatt acttttgaaa aaccgcaatg cactggagca
    19321 agccaatgat ctagatgtga tcatgctgga caaaacagga acactaacag aaggaaaatt
    19381 tactgtaacg ggtgtcgaag tacttgatga tgcgttcaat aaaaatgaaa tccttcaata
    19441 tctaggagcc ttggaagcga atgccaatca tccattggct gttggcatta tgaattattt
    19501 gaaagaacat gaaatcaagc cttatcaagc tgaaaatcta aaaaatcttt caggagtcgg
    19561 gctagaggca acagtcaaaa aacaacaagt gaaaatagtt aatgaaaaag aagttgagcg
    19621 tctcggatta aacgtagaac aagcattatt gaaaccttac caagaacaag gaaataccat
    19681 cagcttcctg attttagaaa atcatctagc tgcaatcgtt gctttaggtg acgtagtaaa
    19741 aacagaagca aaagaattta tccgaacatt gaaagaaaga aaaatcactc ctgtcatgct
    19801 tactggtgac aataaaaacg ctgcccaagc agtagcagat tatttaggga tcgaagaata
    19861 ttatggcggt ttattaccag atgataaaga agctgttgtc cagaaatacc ttgaccaagg
    19921 gaaaaaagta atcatggtgg gtgatgggat caatgatgcg ccaagtttag cccgtgcttc
    19981 aatcgggatg gcaatcggtg cagggacaga tatcgcaatc gattctgcgg atgtcgtatt
    20041 gacaaacagc gatccaaaag atattttgca ttttcttgat ctagccaagc aaacgcgaaa
    20101 gaaaatgatc cagaacctct ggtggggggc aggttacaat attcttgcaa ttccgctagc
    20161 agccggaatt cttgcgccaa ttggtatcat attaagtcca gcagttggtg ctgtcttgat
    20221 gtcgttaagt acggtagttg tagctctaaa tgctttgaca ttgaaaatca aataataatg
    20281 aaaaaa
//
LOCUS       DAIGSZ010000051        20252 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.051, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000051 DAIGSZ010000000
VERSION     DAIGSZ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.051"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            225..1082
                     /locus_tag="NOB31_001982"
     CDS             225..1082
                     /locus_tag="NOB31_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HCI0974184.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1197..2117
                     /gene="pstC"
                     /locus_tag="NOB31_001983"
     CDS             1197..2117
                     /gene="pstC"
                     /locus_tag="NOB31_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HCI0974185.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2117..3001
                     /gene="pstA"
                     /locus_tag="NOB31_001984"
     CDS             2117..3001
                     /gene="pstA"
                     /locus_tag="NOB31_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HCI0974186.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            3016..3822
                     /gene="pstB"
                     /locus_tag="NOB31_001985"
     CDS             3016..3822
                     /gene="pstB"
                     /locus_tag="NOB31_001985"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCI0974187.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3838..4596
                     /locus_tag="NOB31_001986"
     CDS             3838..4596
                     /locus_tag="NOB31_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCI0974188.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4609..5286
                     /gene="phoU"
                     /locus_tag="NOB31_001987"
     CDS             4609..5286
                     /gene="phoU"
                     /locus_tag="NOB31_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HCI0974189.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5524..6554
                     /locus_tag="NOB31_001988"
                     /pseudo
     CDS             5524..6554
                     /locus_tag="NOB31_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
     gene            6551..7318
                     /locus_tag="NOB31_001989"
     CDS             6551..7318
                     /locus_tag="NOB31_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HCI0974190.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7418..8986
                     /gene="liaX"
                     /locus_tag="NOB31_001990"
     CDS             7418..8986
                     /gene="liaX"
                     /locus_tag="NOB31_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HCI0974191.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9283..9603
                     /locus_tag="NOB31_001991"
     CDS             9283..9603
                     /locus_tag="NOB31_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HCI0974192.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9603..9953
                     /locus_tag="NOB31_001992"
     CDS             9603..9953
                     /locus_tag="NOB31_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCI0974193.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10120..11058
                     /locus_tag="NOB31_001993"
     CDS             10120..11058
                     /locus_tag="NOB31_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HCI0974194.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            11073..11903
                     /locus_tag="NOB31_001994"
     CDS             11073..11903
                     /locus_tag="NOB31_001994"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HCI0974195.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKLHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11947..12972
                     /locus_tag="NOB31_001995"
     CDS             11947..12972
                     /locus_tag="NOB31_001995"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCI0974196.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12987..13925
                     /gene="galU"
                     /locus_tag="NOB31_001996"
     CDS             12987..13925
                     /gene="galU"
                     /locus_tag="NOB31_001996"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCI0974197.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            14050..14490
                     /locus_tag="NOB31_001997"
     CDS             14050..14490
                     /locus_tag="NOB31_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HCI0974198.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKATAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14493..15095
                     /locus_tag="NOB31_001998"
     CDS             14493..15095
                     /locus_tag="NOB31_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCI0974199.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15154..16260)
                     /locus_tag="NOB31_001999"
     CDS             complement(15154..16260)
                     /locus_tag="NOB31_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCI0974200.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16470..17471
                     /gene="ccpA"
                     /locus_tag="NOB31_002000"
     CDS             16470..17471
                     /gene="ccpA"
                     /locus_tag="NOB31_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HCI0974201.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17807..20152)
                     /locus_tag="NOB31_002001"
     CDS             complement(17807..20152)
                     /locus_tag="NOB31_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCI0974202.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
BASE COUNT         6442 a         3574 c         4307 g         5929 t
ORIGIN      
        1 ttaactttgg ggtatctctt gttttttggg gaaagcaaga aataagctaa tatatgctat
       61 taaaagagac acatttcaaa gccagtatag catagaaact tttaatgaga tagttttttt
      121 tacaattatg agaatttatt ttgttattta atgattttga ttcgttttca tcaagtaatg
      181 aaaatgataa aataaacata ctttaggatt aaaggagatt tctaatgaaa aaacttaaat
      241 tattcttacc aataatagga ttagccattc ttttatcagg ctgttcaaag tggattgatc
      301 gaggagaatc cattacggct gttggctctt ctgctttaca gcctttagta gaaacagttg
      361 ctgaaactta ccagacagaa aatcctggaa aattcatcaa tgtacaaggg ggcggaagcg
      421 gaactggttt gtctcaagta cagtcaggag cagtcgacat cggaaactct gatttgtttg
      481 cggaagaaaa atcggggatc gatgcctcag cattagtcga tcatcgagta gcagttgttg
      541 ggatcactcc tattgtgaac aaggatattg gcgtaaaaga catcagtatg gaaaacctga
      601 aaaaactatt tacaggcgag atcaaaaact ggagtgaagt cggtggaaaa gatcagccag
      661 tagttatatt gaaccgcgct tcaggaagcg gaacccgtag cacgtttgaa aaatgggtat
      721 tggacggaga aacagctgtt caggcacaag aacaagattc aagcggaatg gtgcgccaga
      781 tcgttgccga cacacccggt gcaatcagct atgttgcttt ttcttatgtt tccgatgatg
      841 tagatacgtt gaatgttaac ggtgtagaac cgacagatga aaatgtgaca acgaacaaat
      901 ggacgatttg ggcatatgag catatgtaca caagagatca tccaaaaaaa ctgacaaaag
      961 aatttttaga ctatatctta tctgatgaag tacaagataa catcgttgga gaactaggtt
     1021 atatccctgt ttctcatatg aaagtcgaac gtgattggca aggaaatatc gttaaagagt
     1081 aatctttaca caaaatttac aaacttagct aaacttttac atgttattaa aaccaaattg
     1141 atgttcaatt tgtacactga gtgagtatgt taaacctgat taagggggag tcatctgtgg
     1201 aagatgtgaa aaaagtatta ttaacaaaat caaaacgttc aaaaatggaa cagcgtggaa
     1261 aattcatcag ttttttatgt atcgcgctga tcgtgttggt tgtattatct attttttatt
     1321 ttgtagctag taaaggattg gccacctttt ttactgataa gatcaatgta tttgattttc
     1381 tgtttggtac agattggaat ccaagccaaa tcggagcaaa tgggaaacca atggtagggg
     1441 cattgcctat gatcacaggt tcgtttattg tgaccttttt atctgctatc gttgccacgc
     1501 catttgccat tggtgcagca gtattcatga cggagatctc tcctaaaaac ggaacgaaga
     1561 tcttacagcc ggtcatcgag ctgcttgtag gtattccttc tgtcgtttat ggttttatcg
     1621 gtttatcagt tatcgtgcct tttgtcagaa gtatttttgg cgggacaggg tttggtatct
     1681 tagctggtac atttgtgttg ttcgttatga tcttgccgac tgtcacaacg atgactgttg
     1741 atgcattaaa ggcagtgcca cggcactatc gggaagcttc attagcgctt ggtgccacaa
     1801 gatggcaaac aatctacaaa gtcgtgctac gagcagccgt gcccgggatt ttaacagcag
     1861 tcgtttttgg tatggctcgt gcgtttggtg aagccttagc tatccaaatg gtcatcggta
     1921 atgcagcatt gatgccaaca ggacttacta ctcctgcttc tacattgacg tccatcttaa
     1981 caatgggaat cggaaataca atcatgggaa cagttgaaaa taatgtgtta tggtcattag
     2041 cgctgatctt gctattgatg tcattattct ttaatatcgt gatccgtatg attgggaaga
     2101 aaggagagct gaaataatga acgcaaaacg ctcagataaa attgctacag gtgttttata
     2161 tatagtttcg gggatcatcg tattgatttt agcagcttta ctactttata tcttagttcg
     2221 gggaataccg catatttcat ggtccttctt gaccgaacct tccaaagcct accaagaagg
     2281 cggtggaatc gggatccagc tatttaactc gatttatttg cttttgatca cgatgatcat
     2341 cagttttcct atttctttag gtgcgggtat ctatctttca gaatatgctg gaaaaaactg
     2401 gctaacagat gtgattcgca cgtcgattga aatcttgagc tcgttgcctt ctgtcgttgt
     2461 cggtttattc ggtttcttgg ttttcgttat tcaattccag tatggtttct cgattatttc
     2521 tggtgcattg gctttgactg tattcaactt gcctcttttg actagaacag ttgaggagtc
     2581 tttacaagcg gtccattaca cacaacgaga agcaggattg gccttaggtt tgtcacgctg
     2641 ggaaacagtg ataaaagtgg tggttccaga agcgacacca gggattttga ctggtgtgat
     2701 cctaagttct ggaagaattt ttggtgaagc agctgcattg atctatacgg ctggacaaag
     2761 tgcacctgcg ttagatttta cgaactggaa tccattaagt gtttcaagcc cgatcagcat
     2821 tttccgtcaa gctgaaacat tagctgtcca tatttggaag atcaatacag aaggcacgat
     2881 gcctgatggt gtttctgttt cggctggcgc ttctgccgtg ttgatcattg ctgttttact
     2941 gttcaacttc ggcgctcgtg cgattggcaa acgattatac cgaaaaatga cttcagccta
     3001 aggagaagaa gcaaaatgaa aaaatataac tggaatgaaa caaatgtcat caccatgcca
     3061 aaagagaaag aagtagcact atatacggat gatctacatg tctggtatgg cgacaatgaa
     3121 gcaatcaaag gagtggatct ggaatttgaa aaaaataaga tcactgcact gattggtcct
     3181 tccggctgcg gaaaatctac gtatcttcgt tcgttgaatc gaatgaatga tgggatcgct
     3241 aatacgaaaa tcactgggaa aatcatgtat caaggcgtag atattaatgc gcctcaagtg
     3301 gatgtttatg agatgcgcaa acggattggc atggtttttc aacgtcctaa tccgttcagc
     3361 aagtcgattt atgacaatat tacatttgct ttgaaacagc acggcgaaaa aaacaaaaag
     3421 aaattagatg aaatcgttga aacaagcttg aaacaagctg ccttgtggga ccaagtaaaa
     3481 gacagcttgg acaaaagtgc cttggcttta tctggcgggc aacagcaacg tttatgtatt
     3541 gctcgtgcga tcgcgatgaa acctgatatc ttgctgctag acgagccggc aagtgctttg
     3601 gaccctattt cgacaggaac ggttgaagaa acacttgtaa acttgaaaga agactatacg
     3661 atcatcatcg tgacgcataa catgcaacaa gcagctcgta tcagcgacta tactgccttt
     3721 ttctatctag gaaaagtaat ggaatatgac aaaactaaca agatatttac cagaccaaaa
     3781 attcaggcaa ccgaagatta tgtgtccggt cattttggtt aagacggagg cctcaacatg
     3841 acaaaagaaa ttatttcatc taaagatctt catctgtatt atggaaagaa agaagcacta
     3901 aaagggatca atctaagttt caatcaaggg gaaatcactg cgatgatcgg tccttctggt
     3961 tgcgggaaat ccacttatct gcgttctttg aaccggatga atgacctgat tccgaatgta
     4021 acgatcaccg gaagtgtttt atataaagac aaagacatct atggtccaaa aacagatgtt
     4081 gttgaactaa gaaaagaaat cggcatggta ttccagcagc caaacccatt tcctttttct
     4141 atctatgaaa atgtcatcta tggattgaaa ttaaaagggg aaaaagataa aaaagtcctt
     4201 gatcaagtag ttgaagaaag cctgaaggca gcgtctgttt gggatgatgt gaaagacaaa
     4261 ttgcataaaa gtgctttatc tttatccggt gggcagcagc agcgtgtatg tatcgcacgt
     4321 gttttggcag ttaatccgga aatcatctta ttggatgaac caacaagtgc gcttgatcct
     4381 gtttctactg ggaaaatcga aagtatgctg ttagaattaa gagagcggta tacgatgatc
     4441 atcgtgaccc ataatatgtc tcaagcttca cgtatttcag ataagacggc attcttttta
     4501 gatggtcact tgatcgaata caacgatacg aagaagatat tcatgaatcc agaaaaacaa
     4561 gagacagaag attatatttc aggtcgattt ggataaggag gaaacggaat gctacgtaca
     4621 caatttgaag aagaattgct gaatctccat aatcagttct acgaaatggg gatgatggtg
     4681 agcagcgccg tgcacaagtc agttcgtgca tacatcaaac acgataaaat cttagcccaa
     4741 gaagttatcg aaaacgatat aaatatcaat aacatggaaa cacgcttgga aaagaaaagt
     4801 tttgaaatga tcgcattgca acagccagtt acaactgatt tgcgtatgat cattacggtc
     4861 atgaaagcta gctcggattt agaacgtatg gccgatcatg cggtgtctgt tgctaaatcc
     4921 acgattcgcg taaaagggca gacgagaata ccggaaatcg aaaaagagat ctccgatatg
     4981 tccgattatg tgaaaaaaat ggtggacaac gtcctagtag cttatgtcaa aacagacgaa
     5041 aaagacgcac gtacgatcgc caatatggat caaagagtca atgactattt caatcgaatc
     5101 tataatgcaa caatcaaaaa tatgcaggaa aatcctgaga cagtcatcag tggaacagac
     5161 tacttgaatg ttgccagtta tctagaacgg atcggagact atgtgacaaa catctgtgaa
     5221 tggatcgtct acttggctac agggaaaatc actgagttaa atacgaacca caatgagatt
     5281 ttctaaactg aagctgtgat tatgccgttt gtttaggaaa agaggttgtg aaatcagcgg
     5341 ttgtgaaaaa gctgttctgc atcaagtaat aagaacagtc aaacaaaaaa tagctcctca
     5401 tatttttcgt ttggctggac ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     5461 ggaaagggtt tgtgacaaaa catgtcacaa acccttttca tcatttcata gaaaggataa
     5521 agaatgcaaa aaaaaattag catcatcact atatttttta tttgtgtgct tacttcatgg
     5581 gttattcagc atcaagctgc tttatatgaa gtacctgtca tcgagatcga aaaagtacga
     5641 ataaaagagg atcatcaatt gattacagga agactgatga acacggatca aaaaggagaa
     5701 tcgatttatt tatcggttcc ttatcaaaaa aatcaaatag aaacagcaaa tataaaagcg
     5761 agacaaatgt atctagtcca aatgcatgga gatgaatggc agctagtagc aaaaaaaaat
     5821 gatggctggc ttttcttctt cacaagtatc ttcattggcg ccatgttgct tattggcgga
     5881 aaacagggtc tatttgcttt aggaagtctc atcatcaata tcgttttact ttacttttgt
     5941 tgctcatctt tactaaaaca gaagggattt ctctattaaa tatatctatc ctgttcgtcg
     6001 ttatagggat gattattagc atattggctt taaatggatg gaatagaagc agtataatca
     6061 aaatttcagc tgcagttacg agtgtttttt tagcattttt tatttgtctt ttgacaatga
     6121 atcattggaa agaccaagga ctgcgctatg aggaactgaa ttatctgaca cgaccgtatc
     6181 gttctgtttt tctttctagc gtactgattg gaacagctgg aggaacactc gataccgtta
     6241 tcacagtcat tgcgacatta gaagaattga ctaagcgaca accagaaata acagcgaaac
     6301 agttatggct ttcaggaagg caagtgggtc gagatgtgat tggctcgatg accaatatcc
     6361 ttttgttcgt ctatatcagt gggtcagttc catcgcttct tttatattta ggaaatcaat
     6421 ggtcgttcaa agaaacgata gaacagcatt tatcattgga atttttacgc gtcattgctg
     6481 gcagcttagg aatagtatta tcgatcccta tctcggtcct cttttttctg actgtaagga
     6541 ggctgaaacg atgaatgtac ttattatact tgttgggatt ttagcaatca gcgtgctact
     6601 tattggcggt acgcaaggta tgtatattct tttaggctta ttcatcaatt tagggatctt
     6661 tttcctgttg ttattcggtt atcatcagaa gtggccgata ctggcattgt cggtcatagg
     6721 atttttattg attgctgtgg ttatcttatt ttttatcaac ggttataatc taaaaatgcg
     6781 tgcagctttt gtgagtatac tgatcttttt attttgtttc ctactattgc ttcctatcac
     6841 tgatttttta gcgatccaag gttttacatc ggtagaacta gaagaattat ctggcttaga
     6901 taagacttta gcgattgatt ttagattact tacgagatcg ttgcttctga ttagtcttag
     6961 tggtgctgtt ttagatgcta gtgtagcaat ttctagtggg acattcgaag tatatcaggc
     7021 aaatccgcaa ttatcttttt accaattgcg ccattctagt ttcgctattg ctaaaaaaat
     7081 attggcgtca acagtaatga cacttctttt tgcattcatg ggaagttctt tagcgttgat
     7141 cctctggttt attgatttag acattccttt tcagcaagtg atcaatgaaa aatcatttgt
     7201 tctagaatat acgatggcta ttcttaccac attgtctgca ctacttgttc ttcctttaac
     7261 ctgcgtgact acagcatatc tctttacaaa aaagaaagaa caactcaaga tggagtaaaa
     7321 gttacaactt aagtcctatg acatttttac tgaatcagtg cataatatgg atgtaaggaa
     7381 aagcttgcaa acaattttgc ttaaggaggc aatttccatg aaagaaagag aacgtatttt
     7441 agatttagtg aaaaaaggaa tcctttcgac tgaagaaggc ttagatttat tagaaagcat
     7501 ggcaactgaa aaagacgaaa agcaaataaa aaaagaagca gacaaggtaa ctgctagtca
     7561 taaagaaaaa gatcaggcaa gtcaattgat cgataaactt gaaaacggcg aagaagaaat
     7621 ttctgagcca gttgatccaa aggaaagaga aagacaagat caagaaaact tagaaaagat
     7681 cttagatgaa ctagcaactg aagcgaataa aacttcggcg cgtctagatg aagtaaatgc
     7741 tcaattcgct gacaataagg cagcacgcaa tgagaaacag gaagcattga tgcagctgaa
     7801 tacaaaagaa gaattaggcg agttgacaga agaagaatta gcacagcgtc agacgttaga
     7861 agcagaaatc aaagaattag aagctagtgg cgatacactg ttagaagaac aattgaaatt
     7921 agaagcagaa ttaaaagata tccgtaagaa tcaatggtct gagaaaaaag aaacgtttac
     7981 tgataagttt gaattgccag atgattggaa agatcaagca acagatacac tgaatcaagt
     8041 aggcgaaaaa atgtcagaag ctggatcaca gttaggcaaa ttcttgaaga aaacattcca
     8101 aactgtttca gaaacagtga atgacaacat ggaatggaaa gatgtcagct tacgtgtccc
     8161 tgggattgcg acaacgaaat ttgagcatga attttactat gaagctcctg cagcaagtat
     8221 ccttgatatc aaggcagcaa acggaaacgt gacgttaaaa acgtgggaca gcaacgatgt
     8281 gaaagttgaa gctaagatca aactttacgg aaaaatgggt gctgaaccat ttgaagcatt
     8341 ctctgaacgg agccagattg aggttaatga agatcatatc tccttccaaa ttccaaataa
     8401 acgtgtgcgt gcagaccttg ttttctactt acctaaacga gtatacgacc acgcagctat
     8461 taaacttcta aatggcaaca tcatgattga aacattggaa gctaaagata tttatacaaa
     8521 atctacgaat ggtaacatca tcgtggacca attaactgca acgatgctgg aagtagaagg
     8581 tgtaaacggc aatatcgata ttcgaaacgg gaacatctta gattctatta tcgaaacagt
     8641 aaatggtaca gtgacatttg gtgcgacagc agaaaacctt tctgtgtctt tggtaaatgg
     8701 tgatgtacgt cttacgatta aagaagataa tttgaaaaaa gtagaagcaa gttcagtgaa
     8761 cggaaatgtc aaagtcgctt taccagatgg catcggtttg gaaggacatg ctaaaacaag
     8821 tcttggaagt atcaacagcc gtctgtccaa ttacgaagta gttcgtgaga aaaaagaacg
     8881 gacaaaccaa atgttgcaat tccgtcgtgt ttcagatggt gaaatcacgc aagtgcaact
     8941 ttcaacgaca acaggaagta tctatttaaa agatacagat aaataaagag gttgtgaaag
     9001 agatgttcag ccttgagcaa taagaagcga ttttgtaaaa tagcttcccc tattttacaa
     9061 aattgtgcct tattgccgat aggctatctc ttgaacaccg tttaccaaga gattatgaac
     9121 ctgccaatta tcgccgagtc acaaggaata atttcagaaa aagctcgtca cgttttatga
     9181 atatggtaat ttgtgaccga gaattttgca gaaagacacc gattaagaag aaggttgtca
     9241 caacgatttt cttcatttaa aatagtagaa cagaggtgag acatgatgaa aaaaaagttg
     9301 acaaaatcca ataaaaatgt tgttttgaca gggactttag caggaatagg agaatacatc
     9361 gggattgatc cgactgttat ccgtgtgctt tatgtattcc tgagcttagt tgcttttgga
     9421 agtccaatca ttttatacat tttattagct ttgattatcc catctgcgcg ttctgcacga
     9481 acaaactatg gacataacaa tgcatattat gaaaaaaaca attatcgtga acaaactcgt
     9541 gaacaaacaa aaaaacgcaa agaagcggaa aaaatcgatg atgacgaatg gagtgacttt
     9601 taatgtcgta ctttcaacgt attttagtta atacgttaac attcatatca ttggctgttc
     9661 tttttcctgc gatggtccat gtgagcagta tttggacggc cgttcttgcc agcttcgtat
     9721 tgtctgtgtt gaatatgttt gtcaaaccga ttttgacgat actgtccctg ccctttacat
     9781 tagtcacatt gggattgttt acgtttgtta tcaatgcagc gattcttaaa atgacctcct
     9841 tttttgtggg agcagaacat tttagttttt cttcattcgg tgcagcgttg ttagtagcta
     9901 tcttgatgtc gcttgtcaat gtaattgtca gcgaacataa cagtagaaaa taaaagaaag
     9961 ctgtgccgaa ctatcggcgc agttttttta tttagaatca ggaatgcgtt ttctattaca
    10021 ttggtaatta aataaaaacg ttttttttaa ttggtagtac ttttggctag acaatgataa
    10081 aatgatagag aacactctaa tagaaatgag gtagcatgaa tgtcagaagt tgtaaaagtt
    10141 agccaattag tgaaaaaatt atctttggaa atcgtgacag gcgacgagaa aagcttagac
    10201 cgtgtcatcg taactgggga catctcacgc ccaggactag agttgactgg ttattttaat
    10261 tattattccc ataatcgttt acagctattt ggcagtaaag aaatcagttt tgcggaacgg
    10321 atgatcccag aagagcgttt gatcatcatg agaagattat gtagtgaaga tatgcccgca
    10381 tttattattt caagaggatt accggctcca gaagaaatga tccaggcagc aaatgaaaat
    10441 gggatagctg tactgcgttc tcccatctca acttctcgtt tattaggaga attatccagt
    10501 tatttagatg gtcgccttgc ccctcgaaca agtgtccacg gtgttttagt ggatgtttac
    10561 ggattaggtg tactgattca aggtgacagt gggataggaa aaagtgaaac agcgttggag
    10621 ttgatcaaac gcggtcatcg attgatcgca gacgatcgag tagatgttta tcagcaagat
    10681 gaattaacgg tgatcggaga accgcctaaa atcctggaac atctaattga aatccgagga
    10741 atcgggatca ttgatgtaat gaatcttttt ggtgcgagtg cggtacgtgg ctctatgcaa
    10801 gtccagttgg ctgtttatct ggaagcatgg gcaaaagata agaaatacga ccgtctgggc
    10861 tctgaagaca cgaccgttga aatcgcggaa gtgggcattc cacaaataaa aatccctgtc
    10921 aaaacaggac gaaacgttgc aatcatcatt gaagtagccg cgatgaattt ccgtgcacgt
    10981 acaatgggct ttgacgcaac gaaaacattt gaagaaagat taagtcgctt gattgaagaa
    11041 aactcaggca acgactagca aggagtgaca atatgttagc acaaatcaat cgagttgctt
    11101 ttgagcttgt agggattcct atctactggt atgcattgat catcgtatca ggtatcatta
    11161 tcgccatgtg gcttagcagc agagaggctg ttcgggtagg attaaaagca gatgatgtga
    11221 cagattttat gttgtgggga ttgcctatct ccattattgg cgctcgctta tattatgttt
    11281 tatttgatct tccccagtat atagctgatc caatccaaat attcaatatc cgttcaggag
    11341 gcttagctat ttatggcgga ctgattgcag gcgcgatcac gctgtatttt tttactaaat
    11401 atcattttat ttctttgtgg acttttttag atatcgctgc accaagtgta ttattagcac
    11461 aggcaatcgg tcgttgggga aatttcatga accacgaagc atatggacca gacacgacgc
    11521 gaagcttctt agaaagtctg catttaccgc aattcatcat tgataatatg tatatcgaag
    11581 ggatctatcg tcaaccaaca tttctttatg aatcactttg gagtttgatt ggatttattt
    11641 tgcttttgtt tttacgaaag aaactacacc ttttgaaaaa aggcgaagtc cttttatgtt
    11701 atctaatgtg gtatagtttc gggcgtttct ttattgaagg attacgtaca gacagtcttt
    11761 actttttagg tgtgatccgt atttctcaat tattatctgc tgtgttattt gtcggtacat
    11821 tgattctatt tatttggcgc agaaaaaaag gaaatttacc ggattatgac cgctcattag
    11881 gaaaaaatca acaaattatc tgatttttag agcgttaaaa atgaaaaaaa tttcaggagt
    11941 ggtaaaatga attatagagt agcggtttta ggaccaggct cttggggtac tgctttggca
    12001 caagtcctcg ccgaaaacgg acatgacgtt cggatttggg gacatcgtgc ttcacaagta
    12061 gaagaaatca acacccaaca cacgaatcaa cgttatttac cagatcatta tctacccgat
    12121 tccatccaag cattcaccaa tatggaagat gcagtaaaag acgcagatgc ggtgctattc
    12181 gtcattccaa cgaaagcaat acgttctgtt gcaaaagaac tagtgcctaa attgaataca
    12241 aagccagtga tcatccatgc aagtaaagga ttagaacagg gaacacataa aaggatctct
    12301 gacatcttgt tagaggaaat cccagcagaa aaaagaaaag ctgttgttgt tctttctgga
    12361 ccaagccatg cagaagaagt agcgaaacat gacatcacta cgatcacagc tgcaagtaca
    12421 gatgcaaaag cagcaaaata tgtacaagag ctgttcatga ataattattt tcggatctat
    12481 accaatcctg atgtgatcgg tgtagagatg ggggcagctt tgaaaaatat tattgctatt
    12541 ggtgctggcg ctattcacgg cttagggttt ggcgataatg caaaggcagc aatcatgacg
    12601 cgcggattag ctgagatcag ccgtttaggt gtagcaatgg gtgccaaccc gctgaccttt
    12661 atcggattaa gcggagtagg cgatctagtc gttacttgca caagtgttca ttctaggaac
    12721 tggcgcgcag gcaacttgtt aggacaaggg cagcccctag aagaggtgct agccaatatg
    12781 ggaatggtcg ttgaaggtgt gaatactacc caagcagcga tggaactagc ccaaataatg
    12841 gaaatcgaaa tgcccatcac tcaaacaatc tatgaagtgc tgtatgaaca aaaagaaatc
    12901 aaaacagccg caaaagaaat catgttacgt gatgggaaaa aagaaaatga attctcatta
    12961 acaatttttt gaaggagcga atgtatatga aagtcaaaaa agcagttatt ccagcagcag
    13021 gattaggaac aagattttta ccagcaacaa aagctatggc aaaggaaatg ttgccaattg
    13081 ttgataaacc aacaatccag ttcatcgttg aagaagcgtt gaaatcagga atcgaagaca
    13141 tcttgatcgt tacaggaaaa gctaaacgac caatcgaaga tcactttgat tcaaatattg
    13201 aattagaaac aaacctaagt gaaaaaggaa agaccgaatt attgaaatta gtagaagaaa
    13261 cgacagatgt caacttgcat ttcatccgtc aatctcatcc aaagggttta ggacatgccg
    13321 ttcttcaagc aagagccttt attggaaatg aaccgtttgt cgttatgcta ggcgatgata
    13381 tcatggaaga tgaagtacca ttgacacagc aattaatcga tgattacgaa cgtactcatg
    13441 cttctacgat cgccgttatg caagttcctc atgatgaaac ttcaaaatac ggaattatca
    13501 atccaggaga agtattggaa gatgggttat acaatgtcaa aaactttgtt gaaaaaccag
    13561 atccaagcaa agcaccaagt gatttagcta ttattggacg ttacttattg actccagaaa
    13621 tttttgatgt attgtccgag caacaaccag gagccggaaa tgaaatccaa ctaactgacg
    13681 caatcgatac attgaataaa acacaacgcg tatttgcccg taaattcaca ggtaaacgtt
    13741 acgatgtcgg tgacaaattt ggttttatga aaacaagtat tgaatatggt ctaacacatc
    13801 cagaagtagg tgcaccttta cgtgagtata tcctgtcttt aggtaaaaca ttagaagcag
    13861 aaggaagcaa gatcgatcat aatccaaaag gaataacaga aatcaaagaa gaaaagaaaa
    13921 aataaccctt ttttctaacg agcttcagct gctaattgaa taaaaagtag ttgaagctcg
    13981 tttttatttg tttaaaaaac acgaaaatgc tatccttata gaaaagagag acaagaaggg
    14041 agtttgatca tgtcaggagg agaaattgca ggattgattg cagcaatcgc ctttgcgata
    14101 cttgtcgttt ttatcgttcg tgtgttgttg caagtttcta aaactttaga aaaagtagat
    14161 cagactgtag cagaagcaaa tacgacgatc gaaatcgtca caaaagacgt agatcttttg
    14221 tctagacaag tagaaggctt gctggtcaaa agtaatgaac tgctcttgga tatcaatgga
    14281 aaagtcgcaa cgatcgatcc attgttcaca gcagttgctg atttaagtga aagtgtatca
    14341 gaacttaatc attctagtaa aaacatcgcg acgaaagtcg gcggaatcgg taaagcgaca
    14401 gctaaagcga cggttgccgg aaaagtcggt gggacagcga tgaaattttt taaaaacaaa
    14461 aaacatactg aaacgacagg aggaaaataa aaatggctaa aaaaggtgga tttttattag
    14521 gtgcagtagt cggaggaaca gccgcagcaa tcgccgcgtt attgttagca ccaaaatctg
    14581 gtaaagaact tcgggatgaa ttagctgccc aagcggatga tttgatggat atggcttcag
    14641 attacacaga tatggcgaaa gaaaaatcga ctgagttaac aggtattgca aaagaaaaag
    14701 cgcaagatct ttctcaacaa gcaggtgatc tagcaggtag tgtcaaacaa aaagtaagtg
    14761 aatcagcaga tgaagcagga agtgaatctg acgatatctt gttaaatctt aaagaacaat
    14821 cagctgactt atctaatcgt ttcaaaaaaa cggcagaaga tatgaaaaaa cctgcagatg
    14881 aattaggaag tattgctaaa gatacttcag aagatatcat gattgatgta aaagacgctg
    14941 ctggtaaagc aggagatact gtcaatgaag gaatgtcaga agcaaaacca gttgcagatg
    15001 acacaaaaga aatgatgaaa atggcaaaag aagatgcgaa agaagctaaa aaagaaataa
    15061 aagatacaat gacagattca tctacaaatc actaaaatca caaatttata gaataaaaag
    15121 gtgggagcgg actagctctc acctttttta ctcttatttt tctaaaacaa gtaattcttt
    15181 tggtgtagtc gtgaatggca cacagccatc gcttgtcaca tatacacagt cttcgatacg
    15241 tacccctact ttttcaggaa tatagattcc tggttcaaga gagaagcaca tcccttcttc
    15301 gattactaag tcatttcctt ctacaaggga agggaattcg tggacggttg ttccgatccc
    15361 gtgacctaaa cggtgattga aatattcgcc gtagccatag ctgttgatca cgtttcgtgc
    15421 gatttgatca agttcacctg ctgtcacacc tggacggacg gcttcttgtg cggcaagctg
    15481 tgcttcaaga gtgatgttgt atattttttc ttggaagtcg gttggttttt gataagcaat
    15541 tgtacgagta gcatcactgc aatagccatt ccaaacaacg ccaagatcga ataacacaag
    15601 ttcattcggt gaaatcttcg tgtttcctgg tgtaccatga gggcttgcag catttgctcc
    15661 tgcaaggact aatgtgtcga aagacatttg tgaaacacct tgttttttca attggtattc
    15721 gatttctgca atgatcgctt gttcagtcac gccttctttc actgctttaa agccaatctc
    15781 aaatgcaaca tcggcccatt taccagcttc gatcagtttg tctttttcct ctagagtttt
    15841 gatcagttgt agacgttgga tgatggaagt tagatcagtg taagaatccg ttcccgtcaa
    15901 gatatcagag atagcatcga agcgctcgac agtcaaggcg ttcttttcaa tccctacatt
    15961 gccaggctga ccatagcgag cacgaagttc ttttccgatg atctcccaag ggttttcgct
    16021 gtctaaatag ccacggacat catacgccca actactgttt tgagcatctt caacttccaa
    16081 agcaggagtg aaaaggaaag gatcttgttc aagagggata aaaagagcta gtacacgctc
    16141 atgaggatca ctttcgtatc cggaaaagta agcgatgtgg ccagggtcgc tgatataagc
    16201 caattcgact tggtgttgtg ccatccattg acgtagttca ttgattttta cgttattcat
    16261 ttggcaacct actttctaaa ttaattttgt attcaataat tgtaccactg atttattaaa
    16321 agaccaacgt tctaaaaact gaaaaaagta aaaattttca tgaaaacaga gataaaacgg
    16381 ttgcaattct tgagattatt tgatattcta ttttagaaat gtaagacgta ttttcagaaa
    16441 acatataaaa tatgaatagg agaacacaaa tggaaaagca aacaatcact atctatgatg
    16501 tagcgagaga ggcaaatgtt tcgatggcta ctgtttcacg tgtcgtaaat ggcaatccaa
    16561 acgtcaaacc agcaacaaga aaaaaagtct tggaagttat cgatcgcttg gattatcgtc
    16621 caaacgcagt tgcgcgtggc ttggcaagta agaaaacaac aacagttggg gtaatcatcc
    16681 ctgatgtcag caatatgttc tttgcttctt tagcacgtgg tatcgatgat gtggcaacaa
    16741 tgtacaaata caatattatc ttagcaaatt cagatggtaa cgaccaaaaa gaagtcaatg
    16801 tattgaataa cttactggct aagcaagtgg acggcgtgat cttcatgggt caccatatca
    16861 cagacgaaat ccgtggagaa ttttcacgtt caaaaactcc tgttgtatta gctggctcta
    16921 ttgatccaga tgaacaagta ggtagcgtaa acattgatta tgtatcagca acaaaagatg
    16981 cagtaaacaa attggcaaaa agcggcaata aaaaaattgc ttttgtcagt ggtgcgttga
    17041 tcgatcctat caatggacaa aatcgtctga aaggctataa agaagcatta agcgaaaata
    17101 acctaccata tagcgaagga ttgatctttg aagcacaata caacttcaaa gatggtctat
    17161 ctctagtcga tcggatccat aatagcggtg caacagctgt ctatgtttca gatgatgaat
    17221 tagccatcgg tattttggat ggtttattag accgtggcgt gaaagtaccg gaagaattcg
    17281 aaatcatcac aagtaacaat tcactactga cagaagtagc tcgtcctcgt ttaacaagta
    17341 tcacacaacc attatacgat ttaggggcgg tatctatgcg cctattgacg aaaatgatga
    17401 ataaagaaga agtcgaagaa aaaacgatta tcttgcctta tggaatcgaa gaaaaaggat
    17461 ctacaaaata ataaaaggac aaccattcag aggttgtgag cctgccgttt aactctgcgt
    17521 tacaaggagc aatttcaaaa aacagcattt catgtttgat gaatattgtg actcgtgatt
    17581 cggagttggc aggagaacac cgtttattcg ggaaaagggg ctatgacaaa attttgttat
    17641 aatccttttt tttgtcttaa aaaagagaga aagtggttga aattacattt atcgtatata
    17701 aaacaatccg tgtatagatg ctgcattatg ttcaccacca tcaaaaaaat aagggactgt
    17761 gacaatacta ttgtcacaat cccttattac tgtgtattct attaaatcaa tcatctttct
    17821 catctgattc tttggttgct tgattcgctc ttgcataagc tgaagcggtg ttccagtaat
    17881 ctgtatagtt ttcatcggta ccgccaacgc caaatttaaa ggcgcttttc ttcggtccat
    17941 ttttcgccca tagcgattca actgtttttc ctggtgtttg gatggatttt ttattgacag
    18001 taacttttcc aggtgtttga ccagtaaatc cagatacttt tttcttcatc acatcagatg
    18061 ataattcgaa tttctcatca gtgccaaaaa tgtcaggttt tgcttggtaa gcttgattga
    18121 tcagattggc aagataatta gccgaacgta tccttgcttt gctgtccatt ccggtattgt
    18181 catcgtgccc tgcccagcta ctgatggtaa tagacggagt agagacaatt agccatgaat
    18241 ctcggtattc attggtagaa ccagtttttc cgacccaatc tgcttttcct agatttccgt
    18301 ttaagcttga gatggcatct ttgaatggtg tagtgatttt tgcattgatc acactgcgca
    18361 tcatgtcatt catgatcgat gccgttgctt ccgaatagat ccggacagag ttgctttcgt
    18421 gtttataaat tacatttcct gcgttatctg tgatggaatc gatgatatag ccttcttcat
    18481 agacgccgcc gtttgctaaa gcctgaaatc cattggtctg ttgaagcgtc gtgacatcta
    18541 ctgtacctaa aggagcagat tcaacgcccc aattgtcatt tgccgggtag ttcatctttg
    18601 ccaagtagtg ctcgtaagca tattgtttcg atccaccgga attcaacaca tcttgatata
    18661 agtgataagc cgggatattg ttggaccatt ctagtgactc acggacggtt tggaaggtgt
    18721 tcgatccttc gttagtagca ttgacgattt tctcgccagc attttctcct tcttgccaag
    18781 ttgttgcata atctgataca cgggattctg atccgataag ccccatgtcg attgcaggtc
    18841 cataaacaag aactggtttg attgatgagc cagcttgacg ttctgtatcg aaggcatggt
    18901 tattttgatt ctgactgtaa ttccgtccgc caacgaatcc gtagatgcgg ccagttctgt
    18961 tatccatcaa tacatttccg gtttctactt gactgccagc accatcatct aacatgtatc
    19021 cataattttc tacgccattt tgcaatgcag catagacatc tttatcgatt gtcgaatgga
    19081 ttgtatatcc tttattttgg atcgtttgct gtgccttttg ataataagcg tcactgaccg
    19141 atgaatcaga catatcagcg ttgtcttttt cagccaattg ttgtgcaatg attcttgttg
    19201 cttcattcat cacagtataa tacaagaatt ctctgtcagt ctgttctgcg atttgttgtg
    19261 gtagaaagtc ttttgtaagg tcataggctt ttgcttcttc gtattgttct ttcgtaattt
    19321 ggccttcacg atacatactg aataaaacaa aatcttttct ggcaaggccg gcagaaagat
    19381 cttcttttag cgcacctgtg ttcgtgtatg gactatacgt gatcgggctt tggggtaatc
    19441 cagcgatata agcagcttgc ggcagcgtca catcttttgc atctacacca aagattcctc
    19501 ttgcagcttc ctggactcca gcaatgtttt gtcccttatt attacgacca aatggtgaga
    19561 cattcaaata cgtagcaatg atctcatctt ttgaaaagta tttttctact tgtgcagaaa
    19621 gaatgatctc atttgcttta cgtttgaatg ttgtttcatc tgtaaggatc tgctgtttga
    19681 ctaattgctg tgtcaaagtt gatccaccag aagagccaat accagtagct tcagatacta
    19741 atgctcgtaa aacagcttta ggaacgtaac cttggtgttt atcgaagtat tcatcctctg
    19801 tgctgataat tgcagttttc aataaaggtg aaattttatc agatgaaata gtcgtgcgca
    19861 tcagatctgt ctggattttt gatatctctg tattatctgc ataaacaatc tttgacgttt
    19921 ctgtaatgtt tcctagttct gtctgcagtg cttttttagt cggcaattgt gtgtcttcga
    19981 cgagataggc aaaatagcca gcgcctattc caatacctag agctgcgaac atcaaaagaa
    20041 gaacagtaat aaaaacagtc aatgattgaa aaactctaaa aataatctta ggaacaaacc
    20101 atttttcttt ttttcttcta ttctgttttt ttcgagtatt tttgcgtggc aaaagggtca
    20161 cctcaactaa tggttttatt tcgctaatta tagcaaataa tagaacaaaa aaacagacaa
    20221 ggctgttttt ggcaggaatt tcttttttaa ag
//
LOCUS       DAIGSZ010000052        20128 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.052, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000052 DAIGSZ010000000
VERSION     DAIGSZ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.052"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            133..636
                     /locus_tag="NOB31_002002"
     CDS             133..636
                     /locus_tag="NOB31_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCI0974203.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            763..1800
                     /locus_tag="NOB31_002003"
     CDS             763..1800
                     /locus_tag="NOB31_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974204.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            1815..3512
                     /locus_tag="NOB31_002004"
     CDS             1815..3512
                     /locus_tag="NOB31_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HCI0974205.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKIPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            3505..3966
                     /locus_tag="NOB31_002005"
     CDS             3505..3966
                     /locus_tag="NOB31_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mov34/MPN/PAD-1 family protein"
                     /protein_id="HCI0974206.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            3979..4839
                     /locus_tag="NOB31_002006"
     CDS             3979..4839
                     /locus_tag="NOB31_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974207.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFFGRSRRFKLYVLQKDYASNG
                     KYSKKYRIFI"
     gene            4877..5266
                     /locus_tag="NOB31_002007"
     CDS             4877..5266
                     /locus_tag="NOB31_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0974208.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            5250..7700
                     /locus_tag="NOB31_002008"
     CDS             5250..7700
                     /locus_tag="NOB31_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0974209.1"
                     /translation="MMYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHD
                     NFRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSM
                     IGDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEE
                     IRRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKS
                     ETLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQ
                     QQQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSV
                     DELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMG
                     LHKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKP
                     ALASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWK
                     ETLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEK
                     FPVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGS
                     ITQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNRE
                     IFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGL
                     KFAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVF
                     EELFHAFDTRPPVQERME"
     gene            7705..9813
                     /locus_tag="NOB31_002009"
     CDS             7705..9813
                     /locus_tag="NOB31_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0974210.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            9810..10814
                     /locus_tag="NOB31_002010"
     CDS             9810..10814
                     /locus_tag="NOB31_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCI0974211.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            10833..11744
                     /locus_tag="NOB31_002011"
     CDS             10833..11744
                     /locus_tag="NOB31_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0974212.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
     gene            11931..12218
                     /locus_tag="NOB31_002012"
                     /pseudo
     CDS             11931..12218
                     /locus_tag="NOB31_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12406..12621)
                     /locus_tag="NOB31_002013"
     CDS             complement(12406..12621)
                     /locus_tag="NOB31_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974213.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(12880..13047)
                     /locus_tag="NOB31_002014"
     CDS             complement(12880..13047)
                     /locus_tag="NOB31_002014"
                     /inference="COORDINATES: protein motif:HMM:NF018933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0974214.1"
                     /translation="MGSECGHTDGKKSFTIREWTCPICRTHHDRNVNVSINILIKGYV
                     YKHCLRKHQEP"
     gene            complement(13392..14831)
                     /locus_tag="NOB31_002015"
                     /pseudo
     CDS             complement(13392..14831)
                     /locus_tag="NOB31_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(15379..16050)
                     /locus_tag="NOB31_002016"
     CDS             complement(15379..16050)
                     /locus_tag="NOB31_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HCI0974215.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
     gene            complement(16399..17850)
                     /locus_tag="NOB31_002017"
     CDS             complement(16399..17850)
                     /locus_tag="NOB31_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HCI0974216.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            complement(17962..19305)
                     /locus_tag="NOB31_002018"
     CDS             complement(17962..19305)
                     /locus_tag="NOB31_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCI0974217.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLEDLFYQNRRELNSKIKKLFLETAVDKIDIQNKKIICVKKDGTRFSQ
                     EYDKLILATGSKQIMLDVPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGKKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHIDNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPVFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            complement(19439..>20128)
                     /locus_tag="NOB31_002019"
     CDS             complement(19439..>20128)
                     /locus_tag="NOB31_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI0974218.1"
                     /translation="NPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTA
                     GNKKGIVVVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTV
                     TLPNGSQYHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNEKDSE
                     KAVSKDNKTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILLGTLGL
                     LGYKNRKKENE"
BASE COUNT         6499 a         3414 c         3742 g         6473 t
ORIGIN      
        1 gagttttcca aactgattgg cttcttggtg attgctttga ttgcggtagg tctggtcttt
       61 aatgcttctg gtgtgaagga tgtcctactc aatttgttta accgaattgt cggtgcctga
      121 gggggaatca caatggaaca gatgcgtgtt tatattgcga accttggaaa atacaatgaa
      181 ggtgagttgg tgggggcatg gtttacccca cctgtcgatt ttgatgaagt gaaagaacag
      241 attggattaa atgacgaata tgaagagtac gcgattcatg attatgaact gccttttgag
      301 attgatgagt atacgccaat tgaagagatt aatcggttgt gtaacttagc ggaggaacta
      361 gaaggaacgc caattggtga agctgcttct gagattcaac acgctttctt caattctttc
      421 gaggaaatgg tagagcatgt ggatgatatt gtctattatc cagattgcga tgatatgagt
      481 gatgtggcgc attacttgat tgtagaagct ggtgattttg gcgaagttcc agaacaattg
      541 aagccgtata ttgattttga tgcttgcggt cgagatttgg agattggagg aaattatttg
      601 gttactagtc gtggagtttt tgagtatcca gaatgaatca aacactatat atagtgtttg
      661 attagtatat gtaagcaaaa aaacacaata tatagagtgc aaactgaagg gtaatgtgat
      721 ataatatttg ccgaagaaat atttttgaaa tgaggtaata ttatggcaaa tattcaaaca
      781 agttttattg atttccataa ttcaattaga ttggacgtag aagacaatac gctacttaag
      841 gactataaag accaagtaat tgatggatta aaagattact tacctgatga tgtgaagttt
      901 gaaacttttt tacagggaag ctattctgtt tataccggaa taaaaagctg tgatgaaaaa
      961 attgattttg acatcgatat tgcagttgct ttcgaaattg atcatactgt ttatgaagat
     1021 ccaagggagc ctaaactgtg ggtaaaagag gcgctagttg aaatttttcc taatgctcaa
     1081 gttaatttaa aagtaccttg tgtaactgct acatttactg gaaaaaagac aaaaaaaaat
     1141 gtgcacgttg atgttgcggt ttatgctaaa gaagatgaaa attatttctt agcaaaagca
     1201 aaagaattca gtgctcccga aaaccgatgc tgggaggaag cggatcccaa agtattaaaa
     1261 gagaaaatta atagtcatgt agcagattca gatgatcgaa aacaatttcg aagatgtatt
     1321 cgctatttaa aaagatggaa agataacaat tttaaccaag aatataaacc aacaggaatt
     1381 ggacttacaa ttaatgtgat ggatacgttc ctagttaata agtccactga ttttttaact
     1441 agaaaagttc agtataatga tatggaatgt atgaagcaga ttgtttcttc gctgaaagat
     1501 tcatttgtgt atgagtacag tgaaacagat ggttggcatt atcgtctaca tgcatatctt
     1561 ccagtgaagc ctaacagtga cacctattca aaaatgacag tgaatcagat gagtgatttt
     1621 aaaaacaaac tttctaaatt atatgatgat ttgattttcg ctatcgatac tgaagatgag
     1681 tatgaagcta caaaacgatt aaataatcaa tttggggagg attttttaat tatttcagaa
     1741 gaagaagtta cagaaaaaaa cttaagaaat gcatttgtta cagactatcc gagtgcttag
     1801 gttggtgtta aagattggat tatactgata ttttaaaaga aaagctaaca gatgttgtgc
     1861 gtttattcga tggtaattac tatggggatt tttcatttgc tacaattgga aagttgcgtt
     1921 taaaaattga aataccaaaa cattttccat tggtacttcc taggatttac attcataatt
     1981 ttgatcattt aggactttac ctaccacatg tagaaaaaga tgggttggta tgtttttctt
     2041 cagatataaa ttatttagta gatgaagaaa attcagaatt ggttttattg cagtgtgtta
     2101 ataaaactat aaaaacaatt gaggaaggtt tgaaagggtt aaataaaaat gattttcgaa
     2161 aagagtttgt tgctttttgg gacaaacaag agaatcaaat ttcgttattc tacctttgtg
     2221 aaccagcgtt gtttatcaag tcagttgata caataatgta cggtaagtct ttggttgctt
     2281 tggataaaga gaacgaatta caattaaatg cagcgagtag attgtttaat ggagagaaag
     2341 aagatactca tgaattagat gcatactatg ttccaattag aaacaagaat aatattatgc
     2401 ccccgaagaa taataaagca tggtcaaaga aggatatttt acaaatagta aaaaaaaatg
     2461 taacaggtgc aaataaaaga ttttttttaa aacttgaaaa aagaaagaat agacataatg
     2521 ttttacttat tctagatatc ccaattgaag aaaagtcaaa taatgtcata attggatttc
     2581 tttttacaaa acaatctgga tctataaaag attataaggg tacgcctagg actgtattag
     2641 ttcagcgtca tgatgaatta tatttggtga atagaacgag cggagaaaac tatggattgg
     2701 gtgctaatat agctattgtt ggggtagggt cagttggcag taaaattgct gaaaatcttg
     2761 gtccattagg tgtgagaaag atgacactca tagacaatga ttgttttcaa gctgaaaatt
     2821 tgtatcgaaa ttcacttggt gcagatagtt taaaaaatgc ccgatctcag aataattttt
     2881 ttaaagttga tttaatgcag gaggagctcg aaaaaaaaat cccatacctt tgtgttgaag
     2941 tggagtcaat gaacgtttta gacttaatta gtatgcaacc tggttttttc aaggaatatg
     3001 actatgtttt tgtttgcata ggagatacaa tggcaagcct ggctttaaat aattattttt
     3061 ccaaaagtag tcaaaaagtt ttctattctt ggctggagcc atatggcatt gggggacaca
     3121 ctctatttat aaattattct ctaaatcaaa aaggttgttt caattgtctt tatacagatt
     3181 caaactctaa aaataggtgt tcaaatagag cttctctggt aaaagaagga caaatttttg
     3241 aaaggacttt agcgagttgc cgctcaaaat ttataccata taatgctatt gcctcgacgg
     3301 aatgtgcaat taatgcaata aaacttttcc ataaagtcaa tcaaaataat atgaccaata
     3361 gtactctttt ttcatggata ggagatggga gtacttttga gaatttagga tatcaatata
     3421 gcgacagaaa tacttttctt aatggagtca ataagtttga agaaagattc ttttctaaat
     3481 attgcaaagt atgtggggag ttagatgatt aaattttcgt gtgaccgtat tgtcattgaa
     3541 gtaagggatg aagttcttaa gatatttgaa caatatcggc agggaaagga tgacttgcct
     3601 gaagctggag gagttcttca tggaaaaaga cttaagaatg ggagcataat aattaccgat
     3661 ataacaacac ctcaaatagg agatatacaa aaaagattac tctttaaaaa aaaccgagaa
     3721 attcatcaac agctttctaa tgagaaatgg atagaatcaa ataagttttc tattgcattg
     3781 ggagaatggc atactcatcc tgaagctgta ccaactccat caaatgttga taagaaaagc
     3841 tggagactga acgtgagcaa gcaacatgat gatagagttt atgtttttat tatcgttgga
     3901 ttttctgatt tgagaatgtg gttactgtca aaaaaatcag atattaggca ggctataaaa
     3961 ctataaagga gtgattaggt gaaatcacaa aagaatattt ggtggtgggg gtttttagta
     4021 ggaaaggtaa tgataccagc ccttctctta atttctctac cgatgattac ttttttcttt
     4081 accaataaaa aaatgagtaa agaagccgtg atttttttct ttggagacca aaaagctacc
     4141 tttattgaaa cgttagtaac atctcttcag cttaatttga attacatttt ttcaattatt
     4201 attgttatat cgttattgaa tttttttaaa aaaagaaatt caggaaaggt gtttaactct
     4261 aatggaaatg tgtactacaa ctatttttat tttgtatttt gggtagcagc aactttactt
     4321 ggttatgata aaattcagat tgcaggaatt cctatacaca tgcaatataa gttggttttg
     4381 agtggaattt tttctgaggt gttgccagat atatacgatg atcattacga cagtgatgga
     4441 acatgtaaag taagcattga aaaagaaaat ttcgatgaca tcgatggata tgactctgtg
     4501 aacttactga ttattgatac ttacgatata aaaatgagtg aattatctat ggaaaatcaa
     4561 acatatccta cgataattgt tagagggaat tcaatagatg gagttcgtaa agttaataga
     4621 tctttaatct tggaaataaa aaaaacaatg gatgaaattc aaaaaagtga ctttaaaaaa
     4681 gtatttgttg cttcaacatc taatccaaaa aatagtatca atattattaa ttcatcgttt
     4741 agatttttcg gtcgatcacg taggtttaaa ctttatgttc ttcaaaagga ttatgcaagc
     4801 aatggaaagt atagtaagaa atatagaatt tttatttaag aaggaatttt tccttctttt
     4861 tattttggag gaaactatga aaaaaataaa aagctacacc agtatttggg cagttgaaaa
     4921 agtcatttat gcgattaatg actttcagct gccttttcct gtgaccttta accagatggc
     4981 ttggtttgtt ttatccttga tgtttgtcat tgtatttgcc catgtgcctc cgctatccat
     5041 gatagagggg gcttttttaa aatacttggg cattccgata gcggtcactt ggttcatgtc
     5101 gcaaaagacc tttgacggta agaaaccatt gggattttta cgatccttta tcagctatca
     5161 cttacggttt aaggtcactt ttgcaggaaa gaaagttaaa gaacagaaga aacgatggga
     5221 cgaaccaatc accttggtaa ggagtgtgaa ttatgtaccc gattaagtat attgaaaata
     5281 atcttgtctt taaccaagaa ggcgagtgtt ttgcttacta tgaattagtg ccttacaatt
     5341 actccttttt gtcacctgaa cagaagtatc aagtacatga taactttcgc caattaattg
     5401 cgcaaaatcg tgaaggtaag atccatgcct tacaaattgc cacagaaagt agtattcgtg
     5461 ccacacaaga acgttcgaaa aaggaaatta ccggtagact caaagaagta gcaaagcaac
     5521 gaattgattt acagacagat gcattagtat ccatgattgg cgatagtcag attgattatc
     5581 gcttctttat tggctttaaa ctgatttcga cagatgaaga ggtcaatcta aagaatctca
     5641 ggaaatcttt cttttctgga cttcaagaat ttgtctatgg agtgaatcat catttgatgg
     5701 gtgattttgt ttccttatcc aatgaagaaa ttcgtcgcta taccaagctt gaaaaactaa
     5761 tggaaagtaa attggctcga agatttaaag tcaaacgagt aacgccgagt gacttgacgt
     5821 atttaattga acatatctat ggtgaaaaag gcacaccgtt tgaagaatat gaattccagc
     5881 taccaaagaa aaagctgaaa tcagaaacgc tggtgaaacg ttacgactta ttacgtccca
     5941 ctcgttgttt gattgaagaa aagcctcggt acttacggat ggaacatgaa aatcatgagt
     6001 cttatgtagc gtacttaaca attaatacca ttgtagggga aatggagttt ccttcctcgg
     6061 aacttttcta ttaccagcaa caacaattta cgtttccgat tgatacttca atgaatgtgg
     6121 aaattgtgac gaataaaaag gccctagcta ccgttcgtaa taagaaaaag gaattaaaag
     6181 atttagacaa ccatgcctat caatctgata atgaaacgaa ctccaatgta ttagatgctt
     6241 tggattccgt ggatgaattg gaaaccacct tggatcagtc gaaagaatcc atgtataaac
     6301 taagctatgt ggttcgagtg agtgctaaat cagtggatga attaaaacgc cgctgtgatg
     6361 aagtgctcga tttttatgac gataccaatg taaaactagt ccggcccttt ggcgatatga
     6421 tgggtctaca caaagaattc ttaccctcaa gtaagcgata catgaatgac tatattcaat
     6481 atgttacgtc tgactttttg gcgggacttg gttttggggc tactcaaatg ctaggagaat
     6541 tagaaggcat ttactttggc tataacgtag atacggggcg caatgtttac ctgaaaccgg
     6601 cattggcatc acaaggggtc aaaggctcag taaccaatgc tttggcatct gctttccttg
     6661 gttcgttagg tggggggaaa tcttttagca acaatctctt agtctattat gccgtccttt
     6721 ttggtgggca agctgtgatt gtcgatccaa aaggagaaag aggcggttgg aaagaaacgt
     6781 tgccagaaat tgcggatgaa attaatattc ttaacttgac cagtaagcca gaaaatcaag
     6841 gcttacttga tccctatgtg attatgaaga aaaagaaaga ctcagaaagt ttggcgattg
     6901 atatcctgac ctttttaaca gggatttcca gtcgggatgg ggagaagttc cctgtgttac
     6961 gcaaagccat tcgaacggtt acccaaagtg atcagcgagg attattacaa gtaatcgttg
     7021 aattgcgtaa agaggactca ccagtcgcgg aaaatatcgc ggatcacatc gagtccttta
     7081 ccgattatga ttttgcccat ttgcttttct cagatggttc gattacccag tcgattagtt
     7141 tagataagca gttaaatatc attcaagtag cggatttggt tttaccagat gcagaaacca
     7201 cttttgaaga atataccacc atggaattgc tgagtgtttc catgctaatt gttatttcca
     7261 cttttgcctt ggactttatc catagcaacc gagaaatttt caagattgtg gacctggatg
     7321 aggcttggag ttttcttcaa gtagctcaag gaaaaacgtt atcgaataaa ttagtgcgtg
     7381 ctggtcgggc catgaatgcc ggtgtttact tcgtcacgca aaacagtgat gacttgttgg
     7441 atgaacgttt gaagaataat attgggctaa agtttgcatt tcgcagtacc gatattcatg
     7501 aaatcaagaa aaccttggaa ttctttggat tagataaaga agatgaaagt aatcaaaaat
     7561 gcatgcgaga tttggaaaat gggcaatgct tgatgcagga tttgtatggt cgagtaggtg
     7621 tggtccaagt tcatccagtc tttgaagaac ttttccatgc ttttgatacc cgtccgccag
     7681 ttcaagagag aatggagtga ggagatgaaa aagaaacttt ttcgtatctt tggaattgtt
     7741 ttaatcagtt tggtcactct gataatactt ttgagcttag ttggaacggt agctgaggca
     7801 acaggtctgg ttgatgatac agttggagcc ggaaatcttt attcccaata ttcacttggt
     7861 aactatcagt tggatttctt tgtggatagt tcgtgggatt ggctgccttg gaattggggt
     7921 gatggcctag ggaagagcgt aatgtatgga ctttatgcca ttactaattt tatttggaca
     7981 gttagtctct acttatcaaa tgccacgggc tacgtggttc aagaagccta taagctggat
     8041 ttcatttcag atacggctga aagtattggg aagaatatcc aaaccttagc cggcattacc
     8101 gaaaatggac tccagacctc gggcttttac tttgggtttc tattattgat gattttagct
     8161 ctaggagttt atgtggcgta tacaggatta ttaaaacgag aaactaccaa agcagtccgg
     8221 gctgtcatta attttgtgat gatttttcta ctttcgggtt cgttcattgc gtatgcgccc
     8281 acctatatca caaaaatcaa tgattttagc tcagatgtca gcgaagcggc tcttagcctt
     8341 ggaaccgaga ttgtcgtgcc gaattcagaa agccaaggaa aggacagtgt ggatttaatc
     8401 cgagatagct tgttttccat tcaagtccaa caaccgtggt tactcttgca atttgatgat
     8461 tccaatatag aagaagttgg cgaagatcgt gttaacaaaa tcctgtctgt aagtccagat
     8521 gaaaataaag gcaaggatcg ggaagaagcg gtcaaagcgg agattgaaga taatgacaat
     8581 gcgaatctca gtattaccaa gaccatgaac cgcttaggga ccgtggtctt tttggtgttg
     8641 ttcaatattg gcatatcctt ctttgtcttt ctcctaacag ggattatgtt gttctcgcaa
     8701 attctcttta ttatctttgc gatgtttttg ccgattagtt tcttattgtc catgttgccg
     8761 acttatgaga gtttgggcaa gaaggcgatt attcgcttgt tcaatacgat tatgatgcga
     8821 gcaggagtta ctttggtgat tacgactgca tttagcatct ccacgatgtt tttcaatatt
     8881 tcggcaacct atccattttt catggttgct tttctgcaaa ttgtgacctt tgccggtatc
     8941 tatttcaaat tgggcgacat tatgaatatg ttcaatctcc agagtaatga tagccaatca
     9001 atgggaagac gggtcatgcg aaaaccgcaa atgttaatga atcgaacatt gcggcaactc
     9061 aatcgaaatg tgggacggac tttggctttt ggtggtggtg cagcagttgg aaataagttg
     9121 gcaaaggaac aatcaaaatc caaatttaag ccatccggtt cttctctacg aaagaattca
     9181 cgattaccga acgatcacga gataccatct gacttgaata aggaaaagcc aattccaaat
     9241 aataagaaac aatcccgaat gaatttggcc gggagaaaag tcggcaaggt tctggatacc
     9301 caagctttgg tgaaagataa gaccaaacaa gtaaaggatg gagtacggaa tacgccaacc
     9361 aacttgaaat acaacttcca taaaggaatt gaaaaaacga aaaaagcacc ggaagagttt
     9421 aagcgaggac tggtccaaga aaaagcaaat cgaggagagt tgcgagaaaa acaacaacaa
     9481 cgtagagacg aaaaaatagc tgaaaagcgc aaagtattga acgaaatagg gaatcctcat
     9541 gggaaaagaa gggaaaatgt tccgataaaa gcaaaggtcc aatctcaaaa ggatagagca
     9601 ccaaagcgga ttgtgagagc aaattcgaat cccgaaatca aacgaaaatt cgctagccaa
     9661 gaaatcattt caaaaggaat aaaccaatcc tcaagtaaga aaaattcttt tcaacaagtg
     9721 aaacggcggt ctactctgtc caaacgaacc aatcgaaaag tacaaaaaag tttgaaccct
     9781 catcccaaac caaggtcagg tgagaaaaaa tgaacgtaaa gaaattaagt gccatttcgt
     9841 taactttcct aacaatctct tttatgggta tcttgatgtg tgtgggctta ttgtttggtg
     9901 aagacagtga aggaagtagt agttcaggtg ctcctcctgg ggggagtagt gtctcagaag
     9961 aggttttgaa acaccgtgca atggtggaaa aatatgccaa agaatcggat ataacagagt
    10021 atgttccgat tcttttagcg attattcaag tggaatctgg tggcacaatg gaagatgtga
    10081 tgcaaagttc tgagtcagcc ggtttaccac cgaattcatt aagtaccgag gcatccatca
    10141 aacaaggatg tctctatttt gcgtctttgg ttaagcgttc caaagaatta ggttgtgatc
    10201 aagatagtat cattcaggcc tataactttg gcggtggtta tttggactat gtggcaaaaa
    10261 acgggaagaa gcatagtttt gctttagctg aatctttttc aaaggaaaaa tcttgcggtc
    10321 aaaaaatcga ttaccctaat cccatcgcga ataaggaaaa tggtggatgg cgctataact
    10381 atggcaatat gttttattgc ttattggtga agcaatacct aactacaaca cagtttgacg
    10441 ataaaacagt ccaagggatt tttgacgagg cgtttaagta tgaaggaacg gcttatgtat
    10501 ttggtgggtc aagacccgaa acaggatttg attgtagtgg cttgactcaa tggtgttatg
    10561 ccaaagttgg tctgaaactt cctcgggtgg ctcaagatca gtatgatgcc atgacccata
    10621 ttgacctaaa agatgccaaa ccaggggatt tggttttctt tcattcgact tatgatgccg
    10681 gtacttatgt gacccatgtc ggtatttatg caggggagaa tcgcatgttt catgcaggag
    10741 atccagtagg ctggacgaat ctaacagaaa gctattggca gcagcatctt atcggtgctg
    10801 gacggtacaa ataagagaaa agaggaaaaa gaatgaagat aaaaattgaa cggaatcaaa
    10861 aggaaaagag cctaaaaaag aaaaaagaac gagtcgtatc cgtgggtaag catcgaaaaa
    10921 tggtgcttgc cctttggctt ttattatctt gtagtcttac ttttggcgtt tataaaaatt
    10981 tcaccgccat tgatcaacat acaactcatg aaaaagtggt tattaaagag aaagtagtga
    11041 atacttctgg tattgaaaac tttacgaagg atttttcgaa agaatatttt tcgtggaaaa
    11101 ataacaaaga agcaattgaa aagagaatga acaacctcga acagtacctt acagaagaag
    11161 gtttcgcttt aagtcaagat atggttcgag cagatattcc cactaattcc gaagttcagt
    11221 cagtaaaagt cttagatgtt gaaaagagct cggaggaatt tgtcgtttca tttttagtgg
    11281 agcaaaagat tacagaggga aaaaaggcac aatcgatttc ttctgcatac cgagtgacga
    11341 tctttgaaga tgaaaacagg aattatatag taacgagttt gccaactatg attgcaaaac
    11401 ctgatagggc aaaatacaag acaaaacaag tagaaaatga ttcgaaaatt gatgccaaaa
    11461 ctacagaaga aatcgctgag tttttggaaa cgttctttaa attatatcca tcagcttctg
    11521 aaaaagaatt ggagtattat gttgaaaatg atgcgatgcg accaatcaat attgacttaa
    11581 agttttcgaa gttagaggat ccagtttacc tacaaaacgg aaaaaaaatt ctagtgagta
    11641 caaagataaa ataccttgat aatgtatcaa aaaccactag ctactttcag tacaaattaa
    11701 tattacaaaa aaatggaaac tggaaaatca ttgatgttaa ataataatga ctcaatctaa
    11761 atttatgaga agttataagt agtttaactt atttcaggca gaagtcgccc atcctctata
    11821 ggtgggtgat gaatgccgtt cggtaactcg aaaaccgaca attaagacat agtgcctttt
    11881 tattttaatc catgtcataa tcagtctata taagaaatgg ttgatatacc atggaattag
    11941 atacaaataa tcattcatta tttcttcttt gttaccacct tattttagta gtgaaacatt
    12001 gtaaacatct cattgatgat gtaatgttag cttatgcaaa aaactatctt tgaaagaata
    12061 tcagaatcac atcacattac cttagttgag tgaaatcgtg ataaagacta ctttcatatt
    12121 atgctcaaag cacaacctaa aaccgaatta acaaaattca gcaatgccta agctcatgtc
    12181 tgataaaatg agactttcta aggatcaaaa atttcctttg aatacgatca ttagcttaga
    12241 taaaagtaaa aaccttagaa ctacggggat agcttggtta ataagagata tcgctgttaa
    12301 taaagacata agcttgcaag tatgctctat tcccaagaat ctcccacttc aagcactaag
    12361 gatcgttaaa ttcagctaag tggcaagtag ttcactagac gataattatc tccatatttc
    12421 aatctcagct tttccatttt tcatagcaaa ttccgttatt tttatagcat ctaaaagatt
    12481 cagcttttcc actgatcttt caccactttt cagctttttt attgtgctta aattgatacc
    12541 agtacctttt gatattgaat tggaagtaaa atcattaagg gtttttttta ttaaattcat
    12601 atccgcaatt ccagcgttca taagaatgaa gattctcctc tcatagacta ctttgaaaat
    12661 ggtactacag tggctgttta tatatttcag taggttactg tagtggtcat tttattataa
    12721 ttagaaaagg aacctaaatc aaaaatgcta aagaaaattt tcatagtatt aaacctatca
    12781 tgactaaagc cacggaattc ttgataaaag agtatacttg caagcctatg tctttactaa
    12841 cagcgatatc tcttattaac caatctatcc ccgttgttcc taaggttctt gatgttttct
    12901 aaggcaatgc ttgtatacat agcccttgat caaaatattg atactaacgt tgacgtttcg
    12961 atcatgatgt gtacggcaaa taggacaagt ccattctcga attgtgaatg acttcttacc
    13021 atctgtgtgt ccacattctg aaccaatttg actagacgga aatcatttat ctatcttgat
    13081 gatttttttg acagaagtat cgaaaatctt tacataatct gggtgttgca ttcttatgca
    13141 gatgagagcg ttagctccgt attcataacc agttgcctct aaaacgtagt ccatcggtgg
    13201 atacctagct tgcggttgcc agtggctttc gcagtcttct tgtaatcaaa tcgagcatct
    13261 aattgagtac tagtattttg aagataatac ttgagttttt cggttttcag aagttcactt
    13321 catcttccat catccatgga aatcccactc acccatacgc aggcctccaa aaattcttca
    13381 acaatggttt ttcagacatt tttctgaata cctccttgtt ttttgatacg ccagatagtc
    13441 aggaaaaagg caacaaaaca caaaacaaag ctgcctaaaa aggtaatctt cattccatat
    13501 aaaaagacat ccggccgatc tgcgatatag ttagttactc gttggcccat cttagcagac
    13561 atcgcttgat ataagaccgt cgtagaaagc gaaatcccga tgaccatccc caaatttcgg
    13621 gcaaaggaat tcatggagcc tgccagtccc aaattttcga tagtgacaga actcataacc
    13681 atcgtattat ttggggactg gaacaaggca ttgccggcac ccatgatggc agtagcgaca
    13741 atgtacagcc acaaaggaga gtccactgac aaaaacatat acatgacttg ggttaccgac
    13801 aataaaccca agcctactaa tacaaaaatc tccgggccaa cccggtcggt caggtatccg
    13861 cttaaaggcg ccccgacgac catcatcaag ggaaagacca tcatcaacag tccggcatag
    13921 ctaggactca acccgcgagc attttgcaga taaaaaggaa tcactacatt aacaaagaag
    13981 ttggaagaaa aaatcaacaa ggctgtaatc aagctcatgg taaaaatctt gttcttaaaa
    14041 ataccgaaag aaatcaatgg agaggctgct ttcttttcaa cttttaaaaa gctgacaaag
    14101 gcaatcactg aaattacgaa cagtacaagg gggactggat ggaaaaagcc actttcttgc
    14161 cccaaaaaga ttgttccaaa aaggctgata atcgtagccg caatggcagc aaagccccct
    14221 ccatcgattg tatggccgct catggtgata tcttttggta agaatttttc agcaatcaac
    14281 atcgttacga ttcccaccgg tacattgatc caaaaaatgt acgcccaaga aaattgggac
    14341 aaaatcaagc cgccaagacc tggtccagca atcgagccta atgaaacaag cgcaccgatt
    14401 gctcccaatg cccgaccacg ttcatgtatg ggaaagactt ccgtgatgat tccggcattt
    14461 gtagccatag tcatactagc accaatggct tgtaccaccc gtgcgaacaa ttaaatacct
    14521 agcgaatgat tgaacccaca caacagcgag cccaagacaa agatcagcgt accaatccga
    14581 aatactttga ttttcccaca gctatcgcca attttaccaa acagcaacaa acaagaacag
    14641 acaatcatca gataaacgga cactacccat tccgcttgat tcattggtat gcccatatca
    14701 tctgagatgg taggtagtgc aatattgaca atactgccat ccaatgtgga catgaaggta
    14761 aacatagata tagcaatcaa aatccaccag cgattttttt ggacttttgc atcttcttga
    14821 taactatgca taataggatt tcctttctaa tgatcgtgta gctaagaaca atataaccta
    14881 tgtctactgc ccaacaactt ctcgcgactc tagccatagg aagcttgagt aatttcgatt
    14941 tgttattctc atgtaaccat gtaagtttga gatgctttat ttgaacttac tctatagtaa
    15001 ctagtgataa ttcgctttac tttcttctag caatttctaa aagtcgactt cattgttctt
    15061 cagattaata gtgtgagcta tctcgtgaga cgtaagaaaa tttccattct actttttccc
    15121 aattttttca tatttatggt gttgcaccta tttgttttcc aatttgcttt tcaaatacat
    15181 tgctatgata ttcaattcca taggattata ctaaatgtca atagtatgaa taatatatta
    15241 tagatgttta tatatcactg ttaattatta tccacaataa ttaatgatta cctcgatatt
    15301 tgtcaatcaa aggttgaaac aatttatttt cagcatcttt tctaacttga gctgcactct
    15361 taatagaatc atacgatcct aaatagtacc tctttttttt aaagttatat acgcaatcca
    15421 tttctcttta gaacgataaa ctcccttaac accacttgta ttatttttcg gtaattttga
    15481 cgttagacac tctattactg tcccttcaac acatgtcctt gtttcttgcc tttttaaaca
    15541 tccacaactt tgagtatgtc caaaaaataa gttactataa cttatctcac acatactgcc
    15601 acactcacat tgacaaaccc attttgtttt ccatgaacag ttattgtcca aaggatactt
    15661 tgcagtaagt aatccgaatt ttttattttc aatgtgatgc ttttttgatt tcaaacatcc
    15721 acagcttttt acatcacctt ttagaagtcg ctttgccgat actaactttt ttctcccaca
    15781 cagacattga cattcccaaa caacagttcc ttcacttcgc agtttagttg gcttgattgc
    15841 aactaactta ccaaaagttt tatttgtcaa atttttatat ttatgcctat ttttataatt
    15901 tccacatcca caacttttgg ttctacctga tagtaagttt gatcgatata caatcgtttc
    15961 attcccacag tcacataggt aacgatattt tttatatcca ttatgagtaa tctcctcaac
    16021 aacagtaagg tgaccatatc tttccttcac tgcacctacc ctcccaagaa agaagtacca
    16081 tataatttca attaactttt aataaatcag aaaaaaatat tttcaatttt tcttagtctg
    16141 attttatgac taatttataa tacaagactg aacgatacgt acacgaaatc ctcaagatag
    16201 ataaattgtt ttcatctagt aaaacctgct caaaatatga gcataaagac ggcaataata
    16261 cactcgatat tcgataatgg acttgtttta tttgtcaaac tcatcgtaat cgagatatca
    16321 attccagtct caatatcctg atcaaaggtc taagaatcca accattttct tgttactttg
    16381 tcagattgat tacctttttt agtctccgaa taataaggtt ttcggatcaa ctaacatgct
    16441 ctgagaaaga ctactatctt tgcaaatttc caaatgaagg tgtgggccag tactattccc
    16501 agtacttcct acatagccaa ttatttgtcc ttgcaaaaca ttatctccag tttttactag
    16561 gtattgttgc tggtgagcat ataacgcggt tgatccatct tcgtgttgta tcaccacgta
    16621 atttccccaa gagtagtgaa actctgcttt aacaacctta ccagctttaa ctgcatgaat
    16681 cggctcaccc tgtgtagctg ccatatcaag tcctcggtga aattcatttc cacgatttcc
    16741 aaacaaactg gttattgaat aattatgaat aggcacttgg tatccagtct tactcatttg
    16801 tggaccttta acttctttat catagttggt taaatcatag gttttaatta attcatttag
    16861 cttcaaatag tattgtgtat ctgttgcata ccgtcctgta aggaatttag ttgcttctcg
    16921 atatgtttta ctattagctt ttaatgctcc tgcataaaaa tctttatttc cactaattcc
    16981 cttagttaat aatttggcat aatcttcaaa actttcctca tagttttcat acactctaaa
    17041 ttttgattgg gtcgtataaa gcgttccatt acccaaatct tcgtttgtta ccataatgac
    17101 aaagtttcca ttataagttc cttttatccc aaataaattg taattcggtg cctgagctaa
    17161 ctggctttga ccactggcag attctaagat cgcttgtgca atcataacag aagcatataa
    17221 atcatatttc tgaccaattt ttctcgcaga ctcaccaatt ttcataataa aattttctac
    17281 agattcattt ttgtcaaaat gaatttcttc attaccagat agtattggtt gtgattggaa
    17341 agattctgtt gattctattt gctgtggtgt cgaaaaattt tttgtttgtc cttccgtttt
    17401 tggcgcttcc ttttttgaag actctatatg gtttggtctt gtcactttcg aagaagttat
    17461 ttcacttgta ctacttgaag ttgttgaaga ttcggcactt gaaatcgtac tactttcact
    17521 tgacgaagtt gttgaagact cggcatttga agtcgtacta ctttcacttg acgaagttgt
    17581 tgaagactcg gcatttgaag tcgtactact ttcacttgat gaagttgttg aagactcagc
    17641 atttgaagtc gtactacttt cacttgataa agttgtcaaa agttcactac tctctgctgt
    17701 tacatcggaa ttactcattt cagtcgtctc ggttctttct tttgcaattt tgtatgttga
    17761 attttcgctt gccaacacat ggaaaggtgt tgctataaag agttgggaca ttaatataac
    17821 tgctgatgca agttttaaag attttttcat ttgatttacc tctctttttt ctctttaata
    17881 gtgttttcta ttaaaaatta tgataaatat tttcaatgaa ttgagtaata cagtatattt
    17941 cttgatttca tttagtaacg attatgtttc aatgtttaat cctgttactg cctttaaaat
    18001 aaaattatag ggttggctaa aactaggatg aaataaataa tctaacattt tcaatttgtc
    18061 taatgtaatt tgttcttcta tagcaagaga aaacattgat aatagtccag ataaatcttc
    18121 ttgactacaa agttgtacac ctactattct ctttgtattt ttttcaaagc taattcttaa
    18181 ttttacacga ctattttttc tcaaaaaaac aggtctaatg aaatcttcta tttctatata
    18241 atctatagac tcacttaata atcgtgctgt ttttaaattc aaacctgctg cgtaaaaatt
    18301 gtaattaaat atagaaaagc catttgtaaa ttgggaacca gaaggtgtaa aatcttgatt
    18361 gtcaatatgt tgagttgcaa tataagctgt tcttagagca ttagaaatag aaaaatcaac
    18421 actacttcta ttaatggacg taaaaaaagt tgtagcacaa tccccaatag catatatatc
    18481 ttttatattt gtttgctggt attcattagt tagatatgct ccactaacat ctctcaagag
    18541 ttcctttttg ccaattggac tattagatag aaatcctata gcttgtacga ccatatccat
    18601 agagtattgg gtaccacttg tagtgactat tttttcaatc ttttttcttc ctaaatattt
    18661 tttaggactt tctgatagac aaagatgtat tccatttttt gatagtattt cttcaacttt
    18721 atctgaaaaa ctacggtcgt aataagtcga caacactcta tctgcaacat cgaaaagata
    18781 tacttctttc cctctttttc ttatggcttc agcaatttca actccaatat atcctgctcc
    18841 aataattcct acttttttaa tagtattatc atctaaagct ttaaaaatct ctttagcatt
    18901 tggaaaattc tttatcgaaa aaatattagc taaattattc cccggtacat ctaacataat
    18961 ttgctttgaa cctgtagcta gtataagttt gtcatattct tgggaaaatc ttgtgccatc
    19021 tttttttaca caaataatct ttttattttg aatatcaatt ttgtcaactg ctgtctccaa
    19081 aaacaacttt tttatcttag aatttagttc tcttctattt tgataaaaaa gatcttctaa
    19141 attgctaact tctcttttta tgaacaacga tgtcccacat tctaagtaac taatttctga
    19201 ttttttatct atcagaataa cttcataatt tgaatcacat aagtttagaa atcgagctgc
    19261 agctagcccc gaatggtttg atccaataat tactattttt ttcacttaat cacattcttt
    19321 tcccttctat gaaaagtatc ttcattttta actaacaacc tatctcccaa aataaaaaac
    19381 aaaaagagga agaaaaagat tcttcctctt ttcagagaag atttaagaaa ttgattttct
    19441 attcattctc tttttttcga tttttatacc ctaataaccc taaagttcct aacaggatta
    19501 aaccaccact aatagtaaag atattactat caatctctcc cgtcttagga taagcttttg
    19561 aggactgctt ttgaggactg cttttgcctc tatttttgtt ttgcttgcta ccttgattgt
    19621 cagtcttatt atctttacta acggcttttt cactgtcttt ttcgtttgaa gaaacaacta
    19681 cattagtagg ttcactagta ttaccagatt catcagttgc agttactatc acttttgttc
    19741 ctgcctctaa tttaggaact ttaactgtaa aattaccatt tttatcagct gtcccatggt
    19801 attgactccc gtttggtaat gtaactgtca cctctgcatt tggttcagtt ttaccagtaa
    19861 caatttggtc accctctgta ataggatcaa cttgaggttt attcggtgct tttttatctt
    19921 ctacagaaat agtaacctct acttcttctt tagatccatc tggatatgtt actactacaa
    19981 tccctttttt gtttccagct gtactaacat ctactttctc tttccaagta taagtagttc
    20041 cttttggtag atcttctttg ttcttaattc cctcagatgc gtctggctct ttatttaagt
    20101 ctgtagtcac tttttgtcct tcaggatt
//
LOCUS       DAIGSZ010000053        20112 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.053, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000053 DAIGSZ010000000
VERSION     DAIGSZ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.053"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..270)
                     /locus_tag="NOB31_002020"
     CDS             complement(<1..270)
                     /locus_tag="NOB31_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0974219.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCG"
     gene            543..3014
                     /locus_tag="NOB31_002021"
     CDS             543..3014
                     /locus_tag="NOB31_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCI0974220.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3117..4853)
                     /locus_tag="NOB31_002022"
     CDS             complement(3117..4853)
                     /locus_tag="NOB31_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HCI0974221.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4850..5554)
                     /locus_tag="NOB31_002023"
     CDS             complement(4850..5554)
                     /locus_tag="NOB31_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0974222.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5685..6188
                     /locus_tag="NOB31_002024"
     CDS             5685..6188
                     /locus_tag="NOB31_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HCI0974223.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6148..6486
                     /locus_tag="NOB31_002025"
     CDS             6148..6486
                     /locus_tag="NOB31_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HCI0974224.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6507..7925
                     /gene="ffh"
                     /locus_tag="NOB31_002026"
     CDS             6507..7925
                     /gene="ffh"
                     /locus_tag="NOB31_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HCI0974225.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8037..8615
                     /locus_tag="NOB31_002027"
     CDS             8037..8615
                     /locus_tag="NOB31_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HCI0974226.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8619..9140
                     /locus_tag="NOB31_002028"
     CDS             8619..9140
                     /locus_tag="NOB31_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCI0974227.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9219..9773)
                     /locus_tag="NOB31_002029"
     CDS             complement(9219..9773)
                     /locus_tag="NOB31_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCI0974228.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10026..10301
                     /gene="rpsP"
                     /locus_tag="NOB31_002030"
     CDS             10026..10301
                     /gene="rpsP"
                     /locus_tag="NOB31_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HCI0974229.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10313..10564
                     /locus_tag="NOB31_002031"
     CDS             10313..10564
                     /locus_tag="NOB31_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HCI0974230.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10689..11480
                     /locus_tag="NOB31_002032"
     CDS             10689..11480
                     /locus_tag="NOB31_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974231.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11650..12171
                     /gene="rimM"
                     /locus_tag="NOB31_002033"
     CDS             11650..12171
                     /gene="rimM"
                     /locus_tag="NOB31_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HCI0974232.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12161..12922
                     /gene="trmD"
                     /locus_tag="NOB31_002034"
     CDS             12161..12922
                     /gene="trmD"
                     /locus_tag="NOB31_002034"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HCI0974233.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13058..13405
                     /gene="rplS"
                     /locus_tag="NOB31_002035"
     CDS             13058..13405
                     /gene="rplS"
                     /locus_tag="NOB31_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HCI0974234.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13778..14440
                     /locus_tag="NOB31_002036"
     CDS             13778..14440
                     /locus_tag="NOB31_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974235.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            14519..17746
                     /gene="fss3"
                     /locus_tag="NOB31_002037"
     CDS             14519..17746
                     /gene="fss3"
                     /locus_tag="NOB31_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HCI0974236.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            17860..18174
                     /locus_tag="NOB31_002038"
     CDS             17860..18174
                     /locus_tag="NOB31_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI0974237.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            18187..18561
                     /locus_tag="NOB31_002039"
     CDS             18187..18561
                     /locus_tag="NOB31_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI0974238.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            18571..18915
                     /locus_tag="NOB31_002040"
     CDS             18571..18915
                     /locus_tag="NOB31_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HCI0974239.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            18986..>20112
                     /locus_tag="NOB31_002041"
     CDS             18986..>20112
                     /locus_tag="NOB31_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HCI0974240.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRD"
BASE COUNT         6770 a         3593 c         4202 g         5547 t
ORIGIN      
        1 tccacaatca tggcagagaa aacgggtacg ttttaattct aaaatagtta acttttcttt
       61 gactttcaac atctgagtgc gtgtcgtata ggaaccgttg cggataatac gaaccgatcg
      121 acagtgttca caataggaag aagagtcatc caattttcct ttaataaact gcgcttgaac
      181 gcctttatat tctttttcaa tcagccattc ttcatcaaaa aataaatgtt tatctgttaa
      241 tccgagtaat tttctagtat gattatccat tgagagactc ctttggtagg atgacgtttt
      301 ggtcgactaa attttaccaa aagtgagtct ctttttgagt tgaaacgaag aaaaagtgtt
      361 agtagaaaat cgccttcgat tttccaccaa cacaaaatat tatagaaccc tttttttttg
      421 ctatatgaca ggaatgaaag gtgtttgcaa gcttaatgtg aggaacactt tccatatctg
      481 ttctatactg gataggagaa gtttggaaat atccagaaaa cgaaatcaat cgaggtagcc
      541 acatgaagaa taaatggata aatcgaagta aaaaaaagaa agtaacacaa agatcatcag
      601 ataaagtcat ccgtcttttt ccatcgtata aagaaggatt aacggcagat caagtcaagg
      661 aacgaataga aaaaggtgca gcaaataatt cagtcgatcc cacattcaaa acaaatcagc
      721 aaatcgtatt ggaaaacata tttacgtatt tcaatttgat ctttcttatc ttagccattt
      781 tgctttgttt agtagaatcc tataagaact tgactttttt accagttatc atagccaata
      841 caggaatcgc catttttcag gaaattcgat ccaaaaagat cttggacgaa ctaaatgttt
      901 taaatacagc aaaagtcaat gtcatacgag acgggataga acaaacaata gatatagaag
      961 accttgtaat agatgacatt gttattttag agactggata tcaaattcca gcagatgcag
     1021 aggtcgtgga agggaaactg caagttaatg aggctttatt gacaggcgaa gcagatgaaa
     1081 taaccaaaga aataggtgat ccattaatgt ccggcagttt cattgtttcc ggaaaagctt
     1141 acgcccgatt agacaaagtt ggagcagatt cgtatatttc ccagctgaca gtcaaagcca
     1201 agacaatggg agaaggagaa cagtcggaga tgattgcttc tcttaatcaa ttgatcaaat
     1261 ggattgggat catcattatt cctatcggta tcctgctttt ttctcaaagt tactttttta
     1321 atggaaacac gatcaaagaa agtgtcgttg caatggaagc agcattgatc ggtatgatac
     1381 ctgaaggact gtacttgctg acgacgattg cattagcatt aagtgcgact aaactagcaa
     1441 agcaaagagt tcttttacac aatatgaaaa gcattgagac attggcaagg gtaaatgtcc
     1501 tttgtgtaga taaaacagga acgatcacag aaaataaaat gtctgttcaa aaaatgatcg
     1561 tctctaaaaa acaagaaata atcagtcagt cagatcaatt ggaagcatgc attgctgact
     1621 atgcaaaagc gatggcagga gacaatgcaa caatggaagc tgttaaagca tattttacaa
     1681 aaaccactga tcaatcctat caccatgtta ttcctttttc ttctgtccaa aaattcagca
     1741 gtgtagcgtt ggcagacaag gtgtatgttt taggagcgcc cgaaatggtt ttgcgcgatc
     1801 aattgccgga atatgcggaa gagtttgttt ctttcgctga aaaaggctat cgcgtgttgg
     1861 tctttggtgt gtacgatggg attcttgaag aaccagtatt gacagaagca gtcacaccat
     1921 taggctatat tctgattgct aatcctatca gaaaagaagc aagagccaca tttgattact
     1981 tcaaaaaaca gcaagtagcc atcaaagtga tttctggaga taatccgctc accgtatcca
     2041 atgtagctgt ccaagcaggg atttcacatg ctgatcagta cgttgatgca tctaaattat
     2101 cagaagaaga atatgaagca gctgtcgaaa aatatacagt ttttggacgc gtcaagccag
     2161 aacaaaagaa aatcttcgtt caattgataa agcgtaacaa tacagtagct atgacaggtg
     2221 atggcgtgaa tgatattcta gccatgaaag aagcagactg cagtatagcg atggcttccg
     2281 gaaatgaagc cgccatgcag gcctcacaag tggtcttact tgattctgac ttttcacgca
     2341 tgccagaagt tgttgcagaa ggacggcgcg ttgtgaacaa tattgagcga tcagccagct
     2401 tgtttttagt gaagaatatt ttctcctttt tgctctcact gttttcagtg atctttgctc
     2461 tgacctatcc tttagaacca tcacaaatca cattgattag tttgtttact atcggacttc
     2521 catctttctt gcttgctcta gaagaaaaca aaaagcgaat cagagggaaa ttcatcatga
     2581 atgtgatgga aaaagctgtg ccaggtggac taacagatat gatcgtagtc ggtgcgttgg
     2641 tgatctgcgg ggtgactttg aatctaaata aaacagatgt ttctacagca tctaccatgc
     2701 ttttgattgc agtagggttc ctcgttctct ataaaatctg ttcaccgctg aataaattca
     2761 gaagtcagat cattcttttc tgtgctagcg gtaacttttt ttcggtcatc tttttgcata
     2821 agctgttttc aatcaccggt atctcagctg tatcactttt gctgttgagc attctatttt
     2881 tctcggcaga ttcgattttt aggcatttga ccacattggt agaatatttg tttgaacgta
     2941 aaaatgaaaa agagcaaaag ccgtttagtc gcgtagctaa aaaatttcta tcgatattta
     3001 aacgagaaaa ttgacgaaaa gtatctcaaa aaagagtaaa aaagaacaac cactcgtgta
     3061 tctttcgaag caggatgagt catccaactt taaaacgcac gagcagttgc tcttttttac
     3121 attttcggaa tggtaacggt gaaagtcgaa cctgttccaa gatgactgtc tacagtaatc
     3181 gtaccattaa ggagttgcac gtagtctttt acaatcgcta accctaatcc ggtcccgcct
     3241 gaatgtcggc ttcgcgcctt gtctacgcgg taaaaacgct caaagatccg ttcctgatcc
     3301 tcaatgtcga tacctatacc aaagtcttgg acagaaaacg atagatcatc tgttgcctga
     3361 tagcggataa taatctcgct gtcgcttttt gaatattgga cagcattttc aatcagattt
     3421 ttgataattg gataaaggat atctgtttta gtagtaaatg gttcgttctt tccaatcaat
     3481 cgaatcgtca accgtttctt ttcgatgatt ggctgataat tttgaacgat ttgctggaaa
     3541 taaggttctg tataaattgt ctggatctcg taagaattct cgccatcttt tgacagctgg
     3601 atgatttccc gaatcagttt atctaaccgg atcgcatctt tttgcatgat ctcaagaaaa
     3661 gaagtcagag tttgcgggtc atcttttgca ccatccagta aagtctcggt aaaaccaatc
     3721 agtgaagtca caggagtttt taattcgtga gagacgttgc caacgaaatc cttttgtagc
     3781 ttttctaaac gtcgcacttt cgttaagtca tacgccaccc ctagaatctg tccggtacct
     3841 tctgaattag taaagtagcg caaactcaag tctaatgtct gccgaccttc tgtaagggtg
     3901 atctcctgat ggatcagcgg atgctcagga gtcacttgat gaatcagctg aatgagtttt
     3961 ggctcttgaa tgacttctgt gtaccgctgt tcaggttgat agcttaccac gtttaaatgt
     4021 agctgcatct ttggattaag cagtagtaaa cgagaatcag catcatcaat caggaatacg
     4081 ccaatcatca gttcgttcag taacgtatat aattgctctt ctgtggtagt acacgcccga
     4141 tacatcttac tcatttgttc gctcaacgca ttaatcgtct gatacaattc ttcccattga
     4201 tcgggtgttt gcatgattac ttccgcctga ttaggatttt gcaccatttt ttttagtacg
     4261 ggcagcacgg ttttcaatgg ctggtttttt tgatagatca gataatagat cattcctgca
     4321 agaacaagga agaaagacag aaagaagaaa aagacccaac ggcgaaaact ctcagttctc
     4381 ggtaaaaaaa cgcttgtcgg ttctgcgata cgtaaaatgg cttctaactg gccacttttt
     4441 ttgactggta atgcgacata taaaagatcc tcattcaaag tagtactttt gcgcaaagcg
     4501 ctacctaggt tcccaccatt caatacggct ttgatttcgg gacgggagtt tcgctgttca
     4561 ttcaatgttt cattgtttgt gtcaaataag atctttccag tagcatccat taaagtaatc
     4621 cgttcgttcg actgatggac gaattcttcc aaagcagttt tgttttgcgc tgcttggagg
     4681 ttttcgacat ctaattgccg gatcagcagt tgtgcttttt ttgtcaggta gctttcttgc
     4741 tgttccacga tctgctgttg aaaataatgg gaaatcaatt gccagccacc aaaaaacaaa
     4801 ctaactaaaa gaataagaaa gaagagacgt tcataaattt ttttccattt catcgtttgg
     4861 gttcctgaaa cttatagcca aatcctctaa tagtcaccaa gtactttggg tgttttggat
     4921 ctcgctcgat tttttctcgc aaatgactaa cgtgtacatc tacgattcgg ctttgtcctg
     4981 cgaagtcaaa attccaaatg cggtctagca atgtgtctcg gtcgatcaca cggtcttttc
     5041 gtttcatgaa ataaacaagt aattcaaatt ctttcggtgt tagttcaatc agatggtcgt
     5101 ctacggtcac ttgataattg gtcaaatcag cagtgatttg tccaatcgat agatattcag
     5161 gctcagcttc atcttttgat tgcttacgag gttcaattcg tctgaatatt gctttcatac
     5221 gggctaatac ttcgcgagga ctaaatggtt tggtcaaata gtcgtcagca cctatttcta
     5281 ggccaatgat ccgatccact tggtcatctt tagccgtcag catcaaaatc ggtgtttcat
     5341 ttttttcttg acgcagccgc tgagtgatct ccatgccatc catcgttgga agcatcacat
     5401 ctaaaatgat gaaatcaaat gattgttcta atgctaattc taatccttcg cctccatctg
     5461 tggcactggt taccttgtag ccttcttttt ccaaattgaa cgtcaagagc gttacaatag
     5521 aaggttcatc atcaacaact agtatttttt tcattcaaat ctcctttaaa taggtttcat
     5581 tctgtttata ttttagcata gaatcagtac aaagggctat tttacaaaag aaataaatgg
     5641 tataatagga aggcactttg ctgaatagaa aggaagagca gtcaatgatt ggaatcagtg
     5701 catgtttagg cggtctggcc tgtcgctatg atggacagaa aaaagaagta ccagaattga
     5761 tggaactagt tgaaactgga gaagctgtca tggtctgtcc agaagtgatc ggcggattac
     5821 caattcctag agatcccgct gaaatcattg gtggaaatgg attcgatgtg tggaaagatc
     5881 aagcaaaagt atggacgaca agcggcgaag atgtaacgga agcgtacaaa aatggcgcga
     5941 tcaaagccta tcaaaaattg caggaaaaac acattgatct agtcatcatg aaggaaaaaa
     6001 gcccttcatg cggaacccat tcgatttatg acggaagttt ttccggaata aaaaaaaatg
     6061 gtgccggagt ggctactgct tattttattc agcaaaaaat gactgtgctc tctgatgaag
     6121 aatggctgaa aactagaggt gagcagaatg gaaatcgaaa agaccaatcg aatgaacgcg
     6181 ctctttgaat tttattcgac cttattgaca gaaaaacaaa tgaactacat ggaattatat
     6241 tatgcagatg atttttcatt aggtgagatc gcggaagaat acgaagtaag ccgacaagca
     6301 gtatatgaca atatcaagcg gacaagcaag atcttggagg attatgaaaa aaaactccat
     6361 cttttttcta attatattgt tcgagaacag gtattggaaa atatgactgc atatattaca
     6421 gataagtacc cggaagataa aaaactactt gaatatgtac agcaaattca agcaatcgaa
     6481 gaataaataa aaggaatgaa gaaaatatgg catttgaaag cttaactgaa cgtctccagc
     6541 aggcgatggg aaaaataaga aaaaaaggaa aagtatcaga agctgacgta aaagaaatga
     6601 tgcgggaaat ccgccttgcc ttactagaag ccgatgttaa cttgcaagta gtcaaagatt
     6661 ttactaagcg cgtacgcgaa cgtgcggtag gggcagaagt gctggaaagt ttatcacctg
     6721 cacaacaaat cgtaaaaatc gttgatgaag aattgacgat cacacttggt tctgaaacag
     6781 cagagttaaa taaatcacca aaaataccaa ctgttatcat gatggctggt cttcaagggg
     6841 caggtaaaac gacctttact ggtaaattag ccaattattt aaagaaaaat gaaaatgctc
     6901 gtccgctcct aatcgcaggg gacgtatatc gaccagctgc gatcgaccaa ttgaaagtat
     6961 taggtcaaca gctagacgtt cctgtatttg atatgggaac tgaagtcagc ccggtagaga
     7021 tcgtccgtca agggatggag ttagcaaaag aaaagaaaaa cgactatgta ttgatcgata
     7081 cggcaggacg tctgcatatc gatgaaacat tgatggatga gttgaaacaa atcaaagaat
     7141 tgacgcaacc aaatgagatt ttgcttgttg tcgatgccat gactggtcaa gatgccgtca
     7201 acgtagctga tagcttcaac cagcaattag gtattacagg ggtcgtcatc actaaacttg
     7261 atggggatac tcgaggcggg gcagcactat cgatccgctc agtgacaggc gcaccaatca
     7321 aattcatcgg ttctggtgaa aaattgactg acttagaagt attccaccca gatcgtatgg
     7381 ctagccgtat ccttggtatg ggggatatgc tgacattgat tgaaaaagcg cagcaagact
     7441 acgacgagaa aaaagcggaa gaacttgcac agaaaatgcg ggaaaattca ttcgatttca
     7501 atgactttat tgaacagctt gatcaagtga tgggtatggg cccactggaa gatctaatca
     7561 aaatgatccc aggaatgaat caagtccctg gaatcgaaaa cgtcaaggta gatccaaaag
     7621 atgttgaacg caaaaaagcg atggtttatt ctatgacgcc agcagaaaga gcaaatcctg
     7681 atctgttgaa cccaagccgt cgtcgccgaa ttgctgccgg ttctggaaac agtgttgttg
     7741 aagtgaatcg aatgatcaaa caattcaagg aatcaagaaa aatgatgcag caaatgtcca
     7801 aaggggatat gaacatccca ggtatggacc aaatgtttgg ttcaggcgtc aaaggaaaac
     7861 taggcaaaat ggcgatgaat cgaatgatca agaaaaataa gaagaaaaag aaaaaacgga
     7921 aataagatga aaaaaacagc ttcggtacag actgaaaatg tctactgccg gagcttttct
     7981 atcagcaatt tttattcttt actaatacaa ttactctaaa cgaagaggtg gcacagatga
     8041 gatgtccgtg gagtgaacaa acagaaagta tgcggcaata tcatgatact gtctggggtg
     8101 ttcctgaata tgatgaccaa aagctgttcc gaaaattgat gcttgatatt aatcaagccg
     8161 gattgagctg gcagacgatt ttaaataaaa gtgaagcatt cgatgaagca tatgatcgat
     8221 tcgatatcaa aaaagtcgca aattatggag aaacaaaaat cagtgaacta atggaaaaca
     8281 aaggaattat tcgtaaccga agaaaaatcg aagcagccgt ccaaaacgcc aaagcagtct
     8341 tgaaaattca agaagaaatc ggcagttttt cagagtatct ttggtcgttt tctaatggaa
     8401 aaatcgttga ttcttcttat cattcacaag aagaagtccc aacaacaagt cctctttcag
     8461 atgaattagc aaaagatcta aagaaaagag gatttaaatt tatcggaagc acaacaatct
     8521 atgctttttt agaagctgtc gggatcatca atgatcacct tgacagttgt ttccgcaaag
     8581 aagaggtcgt acgtatcggc agaaagggcg aataaagcat gcgaaaaatc atattttatg
     8641 gtgctataag tttagatggc tatttggcaa cgaaaacgga tgatcttcaa tggctttttg
     8701 acactccaac aggtaagcaa actacttatg aagcttttta tgaaacaatc gatacgacca
     8761 tcatgggcag aaaaacttat caggaagcaa aaaaatattt ggagaccgaa gcaatttatc
     8821 cagagaaaaa gaatttcgtt ttttccaccc acgcacaatt acaattgcca gatgctgagg
     8881 tcgtaaacga agatcctgtt gcttttctaa aaaatctaca aatgacagaa ggaaaagata
     8941 tctgggttgt gggtggcggt cgattgatca aaccgctatt ggaacatcaa atgattgatg
     9001 aatggtatat ccagattacc cctgtattat taggggacgg gattccttta ttccaaaaag
     9061 gaacatatga agcgcgtttt gaaatgctag acacgacacg attcggtgaa tttatcgaat
     9121 tgcattatgt acgaaagtag aagtaaataa aataaaaaag gcaactatat gcagaaatgt
     9181 cctgtacata gttgcctttt ttattaccgt tatgcttttt actctgttaa tttgttagaa
     9241 aaatctagat acgcatctaa aatcgtttgg aagaaactta atgttccttc aacgatatta
     9301 ccattttcat caattagatt cgcaacgttt ccgatatatg cttccggttg ctgcaaggtt
     9361 ggcacattca aaaagacaag tgattggcgt agatggtggt ttgcgccaaa gccgccgatc
     9421 ccacctggtg atgcagtaac gactaaacct ggtttatgat cccaaacact gtgtccataa
     9481 ggtcttgagc ctacatctaa agcatttttc aatactgctg gcacagaacg gttgtattca
     9541 ggagtaacga aaacgacacc gtctagtccc ctcacttcct cacgaaaacg agtccattca
     9601 gcaggagcct gttctggagt ttcgagatcc tcattgtaaa atggcagatc atcgattttt
     9661 acaaatacac tttcgtaccc ttcaggaagc aatttcgcaa aagcttctgc tacttttttg
     9721 ttgtaagaat cttttcttaa actaccaata aaaaatccaa ttttttttgt catacgattt
     9781 ttcctccttc aaactatcta taataatctt acaaaagata agtaactgga gcaaataaaa
     9841 acacttactg acaaaagcta catagaagat agattactta tttttaacaa aaaagaagtc
     9901 taaaatcttc tattttctaa aaaaaatcga atttaatcaa gctgtaaaga aaaaaagctt
     9961 tacagggtaa aaaaaaactg ttacactaca tcttgtgaat aaaacaatgg aggtggaaat
    10021 aaataatggc agttaaaatc cgtttaaaac gtatgggttc taaaaagagt ccgttttacc
    10081 gtatcgtcgt agctgattca cgttctcctc gtgatggacg tttcatcgaa actgtaggta
    10141 cttacaatcc tttgaaagac cctgcagaag tagttttaaa agaagactta gttcttgact
    10201 ggttatcaaa aggtgcacaa ccttctgaca ctgtacgtaa catcctttca aaagaaggcg
    10261 ttatgcaaaa acaccacgaa gctaaattct caaagaaata aggtgaccgg atatgaaaga
    10321 tttaagcgac ttagtcttaa caatcgttcg tccgctagtc acttatcctg atcaagtcaa
    10381 gttagacgtc gtagagtcga aagactttta cgagtacaat ctaacagtgg ctcctgaaga
    10441 tattggccgt atcattggaa aacaagggcg tgttgctaaa gcaatccgca caatcgttta
    10501 cggtgttcgg atcaatgcac cgaaaaaagt gcgtttgaat atcatcgatg ataaggaaaa
    10561 gtaaataaac gtgctgtact cgaattttcg agtgcagctt ttttgttttt tttattaatt
    10621 gaagaaatga ttatttggca aaacaagcaa gaaagcgtat ccttatagga ggagggagtg
    10681 aacagccaat gagaaagaaa atgttattta ttccatttgc tctattgtta agcgcttgta
    10741 gttcggttac tcaagaatca gacaatacac atctatcaag cagtatatct gaaactgtta
    10801 ccagtccaga aaaaagtagt accaaaacgg cttccaccac tgaacaaaca atggctacct
    10861 caaataatga gaaaaagact gctttagacc agttgaaaga acaacagcca aatgttccca
    10921 tgcctctaga tgtaccagtc tcttcaggct atctcaatat cgcagcgaca catacaaagc
    10981 aaggttattc tattttatat tacagaacag atcgtcccct cgggttgaat gctgacgaat
    11041 tgaatcaaga aacgcctatt gcaacctatc tatatcaata tgggtttgct tctagtcaag
    11101 aaacaatcca agttttgcag ccatttgaga tcgacacaaa tggtcagcaa gtggacttag
    11161 gttctcgaat cacagggtat cagcaaggtg cagcaggttc aagttttctt gaatggcaag
    11221 aaggaaactg gcgtattcga atccgtggga ataatataga aggccaagat cccttactat
    11281 tagctaaaga aatcgtagct tatttggaag aaaacagtct accagcacct gaacaatttg
    11341 gtaaaattac tgttgatatg ggtgatacga cgaatcgagc cgtagaagta agctggcaag
    11401 aaccgaaaaa tgcctatacg atcactcatc aagatcctat gtctgcgttg aagatggcag
    11461 tttctatgaa gaggttgtga aatcagcgcg ctgatctgag cccatcattt aactccaagt
    11521 cacaggaagt aatcaaaaat agcacgccgc atttttgcat aattttggct taatacctta
    11581 aaagaaaact agaattgcct cttcacacat gctaaaataa aacagacaaa aaagaaatgg
    11641 ggatataagt tgactgaata cttgaatgta ggaaaaatcg taaacacaca aggtatcaaa
    11701 ggcgaagtcc gtgttatctc aacaacggat ttcccagaag aacgttacaa aaaaggaacg
    11761 gtgctaacac tattccaaga cggaaaagca cctgtggaat taacagtcaa aagtcatcgc
    11821 aaacataaaa attttgactt attgagtttt gaaggacatc cttctatcaa tgatgtggaa
    11881 aaatatcggg atggcatatt aaaagtgtca aaagacaact ctgtagatct agctgaaaat
    11941 gaattctatt accatgagat catcggtctg catgtattag aagatggaac tgagttaggt
    12001 aaagtaaaag aaatcttgtc accaggtgcc aatgatgttt gggtcgttca acgtccgaaa
    12061 aaagctgata tattgcttcc atatatcgct tctgtcgtca aagaagtcga tttagaagct
    12121 ggagtggtcc gtgtagaaat tccagaagga ctgattgacg atgaagattg atgtattgac
    12181 tttatttcca agaatgtttg aaggtcctat gggggaatcc atcatcggta aggctgtaga
    12241 taaaggatta ttagatatca atatctctaa cttccgcgat tattcagata acaaacatca
    12301 gacagtagat gattatccat acggcggtgg agcaggtatg ctgctcaaag tccagcccat
    12361 ctatgataac atccaagcca ttgaaaaagc tgcaccggat gtcaaaaaaa gagtaattct
    12421 tcttgaccca gctggtaaac gattcgatca gaaaatggca gaagaatttt cacaagaaga
    12481 acacttagta ttcatttgtg gtcattatga gggatatgat gaacgtatcc gcacattagt
    12541 gacagatgaa gtttccttag gagattatgt ccttactggg ggagaattag gtgcgatggt
    12601 catgatcgat gcaacagttc ggcttttgcc agatgtgtta gggaatcaga cttcagctca
    12661 aacggattct tattcaaccg gtttattgga acatccccaa tatactcgcc cggcagaata
    12721 taaagggatg aaagtaccag aagtattgac aaatggaaat cataaattga ttgaagaatg
    12781 gcaattaaaa gaatcactaa gaaggaccta tcaacgtcgg cctgatcttt tggaaacact
    12841 tgaatggaca cctcaaatga cgaaattttt agaagaaatc aagaaagaag aacaagaaaa
    12901 aacagcagat gaagccaagt gactttttct aaaatcttct ttacagtagg ttgataatat
    12961 gttagtattt tatggtgagt gcaaaagcac ttaactatta cgatattccg ctgtgagaaa
    13021 agctcataag aatatttgga ataaggagaa gaaaaccatg aatccattaa tcgaagaatt
    13081 aacaaaagaa caattacgtt ctgacatccc agcgttccgc cctggtgaca ctgtgcgtgt
    13141 tcacgcaaaa gttgttgaag gtactcgtga acgtatccag ttatttgaag gtgttgttat
    13201 caaacgccgc ggtgctggaa tcagcgaaac ttatacagta cgtaaagttt ctaacggagt
    13261 gggcgttgaa cgtacattcc cattgcatac accacgtgtt gcaaaaatcg aagtagttcg
    13321 ctacggtaaa gtacgtcgtg caaaattgta ctacctacgt gcattacacg gaaaagctgc
    13381 tcgtatcaaa gaaatcagaa gataaacacg gaaaacttcc ttggaaatct gaaatttgtg
    13441 aaaagtcctt gtatatcaag ggctttttct tttttctcta tcacagtttt aagccatttt
    13501 tggctgtttt ggaccatttt tcaatcatat tcccttaaaa attgtcctag attgtccgac
    13561 attgactatc agtgtcgtca aaatagggca aaatttagta gtcagcttga cgacaaatat
    13621 aatacgaaaa ataccaaaac atttaccgaa tttagcaact tttgaaccca agtttctcaa
    13681 agggtcagct attagcaaaa aagacaaaac atgtactttt ctactaaaaa gttgatgtga
    13741 taggcttcta tctaaataac tattaggagt ttttatcgtg aagcaaaatg atggacgtat
    13801 catttggaaa aatcaaagtg agttaaaact gattttaaca attaatgaat tcatcgaaaa
    13861 acacggaatt acatctagcc gtcaatacca gaaaaagcta tcagaaaatc caaattctgc
    13921 accaagtatg tggttcatta acaaaaaata tggatcatgg gagaatttat tgattagtat
    13981 aggacgagaa aatactgggt atggaaaatg ggctagaatg tcagaacaag aattattgga
    14041 aatagtagaa gcctttatta agtgcgagaa gataacctct caacgaatgt acgaacaaaa
    14101 atcagtaggg aagaatattc cttcacttag taccattaaa aagatgttag gagatatacg
    14161 tccacttttt aaagaaaaaa atgatggatc tcgatttact gatttcgaac tgctgttaga
    14221 actaaaaaat gaaataatcc gattaaaact acaggatgat ttatcaatga caaagtttcg
    14281 aaaactagtt caatccccaa aactaccatc agttgataca attatgaaaa gaacgaacaa
    14341 aaattgggag gaattgatgg cagagattgg atttgattat cgaagaatca aaatttataa
    14401 gcagagaaac aacctatcca agacaaagaa aactaaatag tatcactcta aatcagacgt
    14461 tcaaaattaa aatttggacg tcttttttat tacccaaaaa cgaaaggaga tttattttat
    14521 gaaaaagcca agatttaaga attggcgttt gctcgcaaca ctgagtctat tatgccaaac
    14581 aattggtgga tcgcttggcc caacgattgc ctttgctgat gaaattactc atccacaaac
    14641 ggtaactgtg gaattggatt tggctcacca gtatgctgtc gaaggtacat ttagcgatgg
    14701 tcgtcccatg tcagaagtta ccgttccgca ctatgcagtt tacaatggtg tgaagcaaga
    14761 tattttctgt attgagccag gggtgccgat ttacaatgag ttcactcctg gttatgagaa
    14821 aaatccattg cctgatatgt cggagaaagc gaaattagtt tccgttttat ggaaggaagc
    14881 tggtacggat gtggatacac atattgtggc ccagaagatg atttggcaag aagttaatgg
    14941 ctacacgctt cactcaatta aacgttctga tggtagtgca gtaaatatcg cagccattga
    15001 gtcaaaaatc aatcaagcca ttgcggatta tcaaaagaaa ccaagcttcc ataactccac
    15061 agtgaaaacc gtgttaggtc aatcgactac tgtgacagat acgaacggct tgaatttatc
    15121 ggagtttgat gaagttgtcg agaatatcgc aaatattgat tatcgtgtga acggcaatca
    15181 actagtgatt actccaaatg ccaattcaaa agagagtggt gaattaaccc taaagaagtc
    15241 agctaataca ggaacaccgg tagcttataa aatggctggt caacaaactt tgatggcggg
    15301 ggcaattgat aagcccaata cctacacaat caaaattgat gtggaaactg agggttcttt
    15361 gaagattaaa aaagtcgata aagaaacagg aaatgttgta ccgggaaccg ttttccattt
    15421 agactttgga aaaacattac ctgcaaaaga cgtgaccacc gataaagaag gcattgcgac
    15481 attggatgag attcctcatg gcgcgaaagt aaccattact gaaaaatcag tgccagctcc
    15541 ttatacgatt gacactacac caatcaccgc aaccattaaa tctggtgaga ctatttctgt
    15601 gacttcaaaa aatactcgcg aaaaaggtca aatcattttg aataaaatgg gggtggaaac
    15661 aggaactgat ctttggaacg acaaatactc attagccgga aatacgtttg ccattcgcaa
    15721 agacagtcca accggtgaaa ttgtccaaga aatgaccacg gatgaaaaag gtcatgcgga
    15781 aacaccaaaa gagattgcca atgcgttgga attgggaacc tattatgtga ccgaaaccaa
    15841 agctagtaat ggctttgtga atacctttaa accagtaaaa gtcgaattga actatgtcaa
    15901 tcaaaccgtg gctcttgtta ccagtaacgt aaaagggcaa aaccaagaaa tcactggtga
    15961 aaccactttg acaaaagaag acaaagatac cggtaatgaa actcaaggta aagctgagtt
    16021 taaaggagct gaatatactc tctttactgc aaaagatggt caagcggtca aatggagtga
    16081 ggcttttaaa ccagagttag tgaagggaac gaaagcttct gatgaaacgg tgactttgac
    16141 tttagatgaa aagaatcaag ttgctgttaa acacttagcg attaatgagt attactggca
    16201 agaaaccaaa gcacctgaag gatatacctt ggatgaaaca aagtaccctg tttccatcaa
    16261 aaaggtggat gataacgaaa aaaatgccgt gattacccga gatgttacgg caaaagaaca
    16321 agtcattcgc tttggctttg atttctttaa atttgctgga tcagctgctg ggactgccga
    16381 aactggcttc aatgatctga cctttaaagt atcgccattg gaaggaacca gtgagattac
    16441 aggtgccgaa gatgaagcaa ttacagctta taacgagcaa ctaggttttg atggctatgg
    16501 caagtttgaa aatcttcctt atggggatta tttacttgaa gaagtagagg ctccagaagg
    16561 atttcaaaaa attacgccat tagaaatccg ttctactttt aaagaaaata aagcggatta
    16621 cactaagagt gaatacattt ttacgattac cgaaaaagga caaaaacaac caattaaaac
    16681 ggtgaccgtt ccttacgaga aactgacgaa taaagcattt tctgttagct tgaatcgttt
    16741 gatgctctat gatttacctg aagaagaaga tagcttaact tctcttggga cttggaaaga
    16801 cggaggcaaa gaattgacag accttgattc taccgagcta gttgataaat tgagctataa
    16861 cttgcatgaa atcaaagaag actggtatgt ggtagcgcaa gccattgatg tggaagcgac
    16921 aaaagctgcc caagaaaaag atgaaaaagc caaaccagtg gtaattgccg aaacaaccgc
    16981 aacgttggcg aataaagaga aaacaggaac ttggaaaatt ttgcataaat taaccgcaga
    17041 acaagttttg gataaaacca tcgtcttatt caactatgtg tatgaaaaca agaaacccta
    17101 tgaagcaggt gatgatccag tagcgaaaga tgctagcttg aacaatcaag cccaaactgt
    17161 caattgtacg gtggaacgcc atgtttccat ccaaacaaaa gcccacctag aagatggttc
    17221 gcaaaccttt actcatgggg atgtggtgga tatgttcgat gatgtgtcga ttacccatga
    17281 tgtactggat ggctcaaaag aagcttttga aacaattctg tatgcattac ttccggataa
    17341 tacgaccaaa gaaatttgga aatctggcaa aattgattat gaagtgaatg acaaagaatt
    17401 cactaaaacc gtacttgcgg aaaaagtgga cacaagtaaa tatccagaag gtacaagttt
    17461 taccttcaaa gaaattaact atggcaaaga cggaaacatc aatgggaaac acaatgagga
    17521 tctaaaagaa aaaactcaaa ctttaacacc taaaaaagtt ccgacaacac caagtgcacc
    17581 agaacaaccg gaaataccaa ctgttccaag tgactctcaa gaatctagtc ctacagtaaa
    17641 gacattccca caaacagggg agaaaaattc taatgttctg ctgtttattg ggtttacctt
    17701 gatctttgcg actgctgggt attatttctg gaatcgccga aactaaggtg atgtgatgaa
    17761 acaactaaat aggaaaaacc aacgtgcgcg accgcctcct aaaaaaagtg gtcgcgctat
    17821 ttttgtatcc aaaactaaaa atgaaaagag gaaaagaaga tggaattgaa atttgttgtg
    17881 ccagatatgg ccgaaacctt tggaaagata aggtatgccg gcgaaggcga agttttaact
    17941 gaaggatatg ggcggaatac tacagtaatt ggtcgtagtt atcatttgta ttccagtaag
    18001 caacgagccg atgatattga agtggtggta gctgcggaag ccggcgaaaa ggattttgat
    18061 caagatcaac cactaaaagc cgtgaatccc catttggttg ccaaaggcta tgagattgag
    18121 aatcgtgggt ttaccgacta cgtgttgtat gtcgatgatt tagtgaaagc ataggaggaa
    18181 aagaagatga gattaacaga aggtattgtt gtagattcag gactaacgtt tgggaaatta
    18241 cgattttccg cattacgccg agaagtacgg aagcaaaatg aggatggaac ggttagtaac
    18301 gaggtaaaag aacggactta taatttgaaa tcctctgcgc aaggtcgaat gatccaagtt
    18361 agtatcccag caaatgtacc cttacgcgag tttgcctatg acgcagaggt agagttggtc
    18421 aatccaatca tggatacggt cgccaattat gttttccgag aaggaactac tgtcaattgg
    18481 ttcattaagg ccgatgattt agtcttgaaa cgacaaccag atcagggaaa ttctacaaac
    18541 caaaatgaag gaaagaaata ggtgaagcgt atggaaatta atgttgaaca tattttagat
    18601 tgtctcgatc aatatggaaa aggtgagcta acggaggaac aactcactaa agcattaacc
    18661 tatgatgaaa aaatgtttct gattatgcat caagggttac tggaagtagg taacgatgcc
    18721 gaagaagatt ttgatgtact gaattggtta ggggaagaag agtccttctt tatggttatc
    18781 gaagtaaatg aaagtctatg tcgagaagcc gaaaccgtat tggaagaaat tggtgtggaa
    18841 atgccggatg ccattgaagt ttttttaaag caactagtgg aaacgaaaca actccctata
    18901 gcagtaaatg actagcataa ctgcttgaaa ttggatcaat gaaatcctat gaagcttttt
    18961 tcgattggag gtggaaacca taaaaatgta caaagggcat cgtatacggg caggagatca
    19021 gcacttggtt tatcactttg ttcttggctg gctactcgct ctgttcatcg gttggatgag
    19081 cgtcttttat tttcaagagc ttagacaatt tgatatttct aagctatcac tttctactat
    19141 agaaatcgtt cgttctataa aagatttaat ctatttgcta ggaagtctcg ttctttcagg
    19201 aagcacgatg ttgctttata tacacttttt tcaggatcat tggcgcagtt tgtggcatcg
    19261 acaaaagcta gcccggatga ttctagaaaa tcattggtac gaagtaaaac aaactcagag
    19321 tgaaggattt ttcaaagacc tcaatagtag tcgaaccaaa gagacaatca gttacttccc
    19381 caaaatctat taccgtatga aggatggttt actttctatt cgcgttcaaa tttcactggg
    19441 aaaatatcaa gatcagcttt taaagctgga aaagaagtta gaaagtggtc tatattgtga
    19501 actagtagaa aaggaactca aagactccta tgtggagtac actttactgt atgatataat
    19561 tgccaatcga attgggatag acgaagtagt ggcagaaagt ggggctttgc gattgatgaa
    19621 aaatcaagta tgggcttatg attctttacc tcatatgtta atcgctggcg gcacaggtgg
    19681 tgggaagact tactttttac tcactatcat cgaggcttta ttaaaatctg atgccgagct
    19741 ttttgttctt gatcccaaaa atgcggactt agccgattta ggtacggtaa tgcctcatgt
    19801 ctattcccaa aaggaggaaa tttctgcttg tgtggaagat ttctatgagc gcatgatgac
    19861 tcgtagcaag gcaatgaaag aaatgcccaa ctacaaaaca ggagagaatt atgcgtttct
    19921 tggacttcca ccaaactttt taatctttga tgaatacgtg gtttatatgg aaatgttaac
    19981 gacgaaggaa agtgcggtga ttttgaataa gctcaaacaa atcgtgatgt taggtcgtca
    20041 atctggtttc tttctgattc tagcttgtca aagaccggat gcgaaatatt taggagacgg
    20101 gattcgcgat ca
//
LOCUS       DAIGSZ010000054        20064 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.054, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000054 DAIGSZ010000000
VERSION     DAIGSZ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.054"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            212..1018
                     /gene="proB"
                     /locus_tag="NOB31_002042"
     CDS             212..1018
                     /gene="proB"
                     /locus_tag="NOB31_002042"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HCI0974241.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1015..2262
                     /locus_tag="NOB31_002043"
     CDS             1015..2262
                     /locus_tag="NOB31_002043"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HCI0974242.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2338..2682
                     /locus_tag="NOB31_002044"
     CDS             2338..2682
                     /locus_tag="NOB31_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974243.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2799..3125)
                     /locus_tag="NOB31_002045"
     CDS             complement(2799..3125)
                     /locus_tag="NOB31_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974244.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3498..4700)
                     /locus_tag="NOB31_002046"
     CDS             complement(3498..4700)
                     /locus_tag="NOB31_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0974245.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4817..5332
                     /locus_tag="NOB31_002047"
     CDS             4817..5332
                     /locus_tag="NOB31_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0974246.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5531..5977)
                     /locus_tag="NOB31_002048"
     CDS             complement(5531..5977)
                     /locus_tag="NOB31_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCI0974247.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6024..7502)
                     /gene="msr(C)"
                     /locus_tag="NOB31_002049"
     CDS             complement(6024..7502)
                     /gene="msr(C)"
                     /locus_tag="NOB31_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCI0974248.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7856..8485)
                     /locus_tag="NOB31_002050"
     CDS             complement(7856..8485)
                     /locus_tag="NOB31_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI0974249.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8469..8933)
                     /locus_tag="NOB31_002051"
     CDS             complement(8469..8933)
                     /locus_tag="NOB31_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0974250.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9420..10688)
                     /locus_tag="NOB31_002052"
     CDS             complement(9420..10688)
                     /locus_tag="NOB31_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI0974251.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10919..11656)
                     /locus_tag="NOB31_002053"
     CDS             complement(10919..11656)
                     /locus_tag="NOB31_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0974252.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11723..12292)
                     /locus_tag="NOB31_002054"
     CDS             complement(11723..12292)
                     /locus_tag="NOB31_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCI0974253.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12420..13292
                     /locus_tag="NOB31_002055"
     CDS             12420..13292
                     /locus_tag="NOB31_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0974254.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13634..14506
                     /locus_tag="NOB31_002056"
     CDS             13634..14506
                     /locus_tag="NOB31_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0974255.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14503..16461
                     /locus_tag="NOB31_002057"
     CDS             14503..16461
                     /locus_tag="NOB31_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0974256.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16712..17563)
                     /locus_tag="NOB31_002058"
     CDS             complement(16712..17563)
                     /locus_tag="NOB31_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0974257.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17686..18153
                     /locus_tag="NOB31_002059"
     CDS             17686..18153
                     /locus_tag="NOB31_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HCI0974258.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18295..18777)
                     /locus_tag="NOB31_002060"
     CDS             complement(18295..18777)
                     /locus_tag="NOB31_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCI0974259.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18877..19740)
                     /locus_tag="NOB31_002061"
     CDS             complement(18877..19740)
                     /locus_tag="NOB31_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCI0974260.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6034 a         4131 c         3639 g         6260 t
ORIGIN      
        1 aaactactcc tattctaaca tatccgaggc tgtaaaagac tttctttaca aattcttcaa
       61 gaaattctgc tatcttaaag taaaccatta attcgttctt tttccaaacg actacaagtt
      121 gtacaaaaaa actatttttt acatgacttt actcgtcaaa acaagtagaa tagaacgaaa
      181 ttaatgagtg gatatttgat tgaggtgtca catgcgtaaa gaaattaaaa atgcaaaacg
      241 aattattgtc aaagtaggaa caagtacatt gatttatccc aatggaaata tcaatcttgc
      301 ggcaatcgat cagttagctt ttgtcctttc tgatcttaga aatcggggaa aggaagtgat
      361 cttagtctca tcaggagctg taggcgttgg tatgcataaa ttacatttgt cagaacgtcc
      421 gactttgatt cctgaacagc aagctgcggc ggctgttggt caagccgaac tgatgaatat
      481 ctataatcaa agattcagtg tatataatca acagacggca cagatcctcg tgacaagaga
      541 cgtggtagat tatcctgaaa gtcgtaaaaa tgtgaggaat acattggaac agcttttgat
      601 tatggacacg atccctatcg tgaacgaaaa cgatactgta gcagtggatg aattagatca
      661 tctgacaaaa tttggcgata atgatcagct gtcagccatc atggcaaaac ttgtcgcggc
      721 agaccttttg atcgtccttt ctgatatcga cgggttttat tcagataatc cgactacaaa
      781 tcccgaggct cagatgtatc gctatatcga taaaatcgat gaaaagattc tggcacaagc
      841 aggtggtgct ggtagcacat ttggaacagg cggtatgcag agtaaattaa aagccgcttc
      901 taggatattt gaagcaaaca gcgcaatgat tttagcaaat ggaaaaaatc cggcaattat
      961 ttttgatatt cttgcaggaa aagaagtagg tactttattt aaggaggact tgaaatgact
     1021 gacttgatgc aattaggaca acaggcaaaa gatagcgcgc aacaactagc acttatgcct
     1081 acaaaccgca aaaatgagct acttgttcaa atggcacaaa ccatcaaaaa gaatcaacaa
     1141 gcgatcattg aagcaaatca taaagactta gaaaaagcag tcgaaaacaa tatcagtgaa
     1201 acgatgcaag accgcttgca gctgacacct gagcgaatca atgccatggc tacagagatc
     1261 gaaaaaattg cttcgttaga cgatcctatt ggaaaagtag atgagatgtg gacgaacacc
     1321 gacggattga gaatcggcaa aaagcgcgtg ccactaggcg tgaccggcat catttacgaa
     1381 tctcgtccaa atgtcacgac agatgcagct agtctagcat tcaaatcagg gaatgccgtt
     1441 atccttcgcg gtggcaaaga agcattcttc tcgaatcaat tattagtcca attattgcag
     1501 caagtactgg tcagtgctgg cgaatctcct tatgccatcc agtttgtcga tgatacttct
     1561 catgaaactg caggacagtt gatgcgattg acagaatact tagatgtgct gattcctcga
     1621 ggcggagcaa aattaatcca acgagtcaaa gaacaggcaa cggtacctat cattgaaaca
     1681 ggtacaggaa ataatcacgt atatatcgat aaagaagcac agttatctat ggcagtgaac
     1741 atcatcgtca atgcaaaagc ttcccgtcca tctgtctgta acgcggcaga aacattgctg
     1801 atccattctg agatcgcacc ttttttcttg ccagctattg aaaaagaact ggtagaacac
     1861 ggggtctctt tacgtgcgga tgctcgtgcg ttagaatatc tagagacggc tgctttagca
     1921 gaagacacag attgggatac tgaatatcta gattatatcc ttgctgtcaa agtggtcgat
     1981 tctttggatg aagcaattgc acatatcaat cggcataata ctaaacattc agaaacgatc
     2041 gtgacagata gttatgcggc tagtcaacgt ttcttaaatg aagtggacgc ggcggctgtc
     2101 tatgtcaatg cctccactcg ttttacagac ggatcggtat ttggttttgg tgcagagatt
     2161 ggtatctcta ctcaaaagtt gcatgcccgt ggtccaatgg ggttaaatga attaacttcc
     2221 acaaaatata tcatttatgg cgatggacaa atccgcgaat aatgtttcgt gtgaaacatt
     2281 attcccgcct tttgcctttt ttctgtaaag gttctatcca actagaaagg tgtcaatatg
     2341 tttgaaattt taatgatttt ttttatttac cttatttctc tgaatatcgc tgcttttctg
     2401 ggagtcggta ttttatccct tttctttcaa ttcaaaaaac gaagcatagg gagtcaacgg
     2461 gaaaaatggt cgcagtattt tgacaaaatc gggcaaaaag ggctggttac acgcttgcac
     2521 attagttaca tggttgcatt atgcttatta gcgacaatca attactattc ttttttcgat
     2581 cattcaatcg cttatacgat tacgctactg attgctggga tttttcactt atcttataaa
     2641 tatcagctga ataaaaacca cttgaatcgg actttccgct aaaaaatatc cgtacgataa
     2701 gtagagtgcc ttgaagatcg gcaaaaaact gccggacttt ttagaggctg tgacaaagat
     2761 tttgtcacag cctctttttc catataaacg gcgttcgcct accagctgcc tggtaaatct
     2821 gtttcctctt cgttaagaag cgaaaatccg tcaaatgttt cgccatcata ataacgaagc
     2881 agctcatcca tggacaagtt catcgttttt tctttttctt cttccgctga ttcagccagt
     2941 agctgttccc gatacacctg atacatacca gctatttttt gctgcatcgc ttttctagtt
     3001 tcaccttccg cattgattat tggcaattct ttgatatagc cacgataaat caaccgatca
     3061 tctgaaaatt caatgggtaa ttcaacgagt gtcaacccga cttcctgaaa atattcttcc
     3121 agcatctatt atccccccat tctttttctt aaatgaattt tagcttacct actgaaaatt
     3181 ttccagtttc attattttga gaaaaaaagg gaatgtgaca aaaatcgtgt cacatcccct
     3241 ttttccgaat aaatggtgtt cttctgccaa ctcctcaatc ataagtcaca atattcaaca
     3301 aacatgagaa actgtttttt gaaattgttc cttgtgattc agagttaaac gacagtctca
     3361 caacctcttg gtaaacggcg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg
     3421 aaaaatatga gaagctattt ttgtttggct gttcttatga cttgatgcag gacagctttt
     3481 tcacaacctc tgatttctta ttcttcttca tttgtagcaa aataattacg gtgataaatg
     3541 atacaacata cactgataag aacaatggca cctgcaaaat aaaacgcata gctttcacca
     3601 atatgttcac caatcacacc tgcaataaat ggtgctaaag ctccaccgaa aaagcggaca
     3661 aaactatagc tggacgaagc aacgtttcgt tgcagacctg gtatttccat agcaatcgtc
     3721 gtcaacagtg tattgataat tccttggaaa aatcctgcta acacaatgct gatcggtaca
     3781 aggactggca tagaagttcc agctcctaat aacagcaaac aaataatgaa taagacaaat
     3841 gctgctaaaa ttgtccgata agtcgtaaac ttccgctcaa gagccggtgc aacgaaaatc
     3901 gaagcaatag ccagaagcac accccagcca aaaaatacaa aaccgacttc taattcagaa
     3961 tagccaatca ataaaaatgg cgcatacgca agtaaagtaa agaatccgaa attatataac
     4021 aatgcgatta gtccaactga acgaagttta tgattgctta acgctttgac accttcccaa
     4081 aggcctactt ttctctttgg tttctcagtt tcaggtaaaa gtaccgctag ggctataaaa
     4141 ccgcaaaaca tcaaaaatgc taccccaaaa aatggataac gccatgaacc actgcccaag
     4201 accccaccga ctagagggcc aacagccatt ccgcagccaa gtgctgcttc atacatcatg
     4261 attgcttttt ctgtgttacc aactaaaata ctgacgatcg ttgctaaagc agtagagaca
     4321 aataaagcat tcccgacacc ccagccggca cgtaacccaa tcagcattcc gatattccca
     4381 gataatccgc caagaccagc gaatacaacg atgataaaca atcctgtcat caatgttttt
     4441 ttcaaaccga tccgactaga taagaaacct gtaaatagca tcaccacacc agtgactaac
     4501 atgtaactag taaataacag ggtcgtttca gctggcgtag cgtttaactg tgcagcaatc
     4561 gtttttaaga ttgggtctac tagacccact cccataaaag cgatcataca ggtagctgct
     4621 acaactagcg ctgaactttt cccctttgtt tcttcatttg tttgttcttg tatatctatt
     4681 tgattctcca atatttccat ccctttctct ctattagcat catacatgat ttattttaca
     4741 tgtaaatatg cacatgtaaa acgtggaaac tttactgtga tataataaag aaaataagac
     4801 gagaggtagg atttttatga atactttagc ctatatatta ttatgcgtgc ttttatccaa
     4861 accacgttct gggtatgaat tgaagcagct gatcacaatt ttttgggaag cccatcacag
     4921 tcagatctat acaacgcttg ccaagttaga ccagcagggt tatgtgaccg ttttggacaa
     4981 agacgagcac tctcaaaaaa agatctacca cttgactgat gaaggacgtg ctcttgtaga
     5041 ggaatggatc aaagaggaaa ctcccgctcc tacgcaaaaa gatgaatttc tagcaaaaat
     5101 ctatgctttt tcgacgctcg ataaaacaac agctactgga ctgctattca ctagagaaca
     5161 acagctgaac aaaatcatgc aaaaaaatca aaaaaaattg aatgacctct cgctagacaa
     5221 gaaacaagaa tttggacgtt atgttgtgat ccagcgcaga attatgcttt gtcagcagga
     5281 actccaatgg tgtcagcaag taagagaaca aatgcagcag ttttttgagt aagggataaa
     5341 cagaaccttt ctagaaatat ctattgaaga gcaaattatc ttcaataaaa gagcaataca
     5401 gttggaaaag aaaaagcgat ccgaacgaca ggccaaaacc tatcgttcgg atcactattt
     5461 ttctagaact gcattcaaga gactatgaca aaaagcatgc caaggccttt tttcaaataa
     5521 cagtgttcca tcattcatta ctttgaattg cttttagcac acttcttgaa agcgggccaa
     5581 cgatgatcaa ctgcaacggt aaagcggcaa tcacattcat tttccaagca ttcatataag
     5641 cagagaataa ttgatcaggt attccttgtt ccatgatcac accgaataaa gacatacatg
     5701 tcaccattcc taaaaccatc aagcatgaaa tagttaagat catttggacc ttgctttctg
     5761 gatttactgg tagtttaaag gcaatttttt tcgccagcac accgatgatg aagacatcca
     5821 aaatgaaagc caccacgaat ccaggcacta gaccaatcaa caaacttgat aaatgaagat
     5881 cttgatgcag ccataaatta tacgcgctca tccccaagac catcaaaaaa cacatcattg
     5941 ttgtaaaaat tattccttct tttttatttg taggcaatct gtaccactcc tttaaatttg
     6001 tcacgaaaat catcgtagca catttaaaaa tttctcgtaa gtactttttt tattttctgc
     6061 ccttttattt cataaacttc atcagccgta cgctcgacaa agtaagaatc atgagaagta
     6121 aacaaaatcg ttcccggata tatttgcatt agcttctcta aagcttcgat cgttgccata
     6181 tcaataaaat tagtcggttc atctaacagc aacacattac ttggcttagt aaaaagcaaa
     6241 gcaatcgtca gacgggtcgc ttctccccca cttaatgtac ataacggttt cgtcaaagtt
     6301 tcctgagcaa accctaagtg attcagcaaa ctacggacaa gcgattctga aaactctgtt
     6361 tgtctcatga caaaacgaat gatggattct tcagatgtca tttgataacc cttttgctga
     6421 tatacttgaa agcttacttt cggagagaga aggattcctt ctccttgttt gcggatatgt
     6481 tctaataagg ttgtcttacc tgaaccattt tcaccgacaa tcgcgatttt tttacctaaa
     6541 gaaaactgaa aatcaccatt taccagtaat gttctcccac ttctttccaa ttggacattt
     6601 tgtcccatga tgggatagcg gctgtggagt tcaagagatt ttggtactgg aaaacggatt
     6661 tgtttcatct gctgcggctt ggttgtttct cctatttttt ggagtcttct ctctaatgtt
     6721 ttcgcattct tttggatggc tttttgtaca ctgtcttttt gtttagagga agacaaccga
     6781 tccggtctga tttgttgctt tttcttttta ctggacactt tttccaactt ttccgcttgt
     6841 tttttctttt cttggatcga tttttccaat cgttttttct ctttcatgat cgactctgct
     6901 tctcgtagct gagtcttttt ctccaattcc ttttgagtga gataggcact ataattcccc
     6961 gaaaactctc ggatttctcc gtcttttact tcccagattt tcgatgctag ctcatctaga
     7021 aaatagcgat catgactaac aaaaaccagc gtaccataat aataacgaag ctcttcaatc
     7081 agtcgatcaa tactttttct atctagatgg gttgttggct cgtctagaag catcccttgt
     7141 tcataagaag aaagaagacg tatcaactcg atctttcgtt cttcccctcc gctccatttc
     7201 cgctctgaag tttcttccag tcttaactgg aaatgactgg ctaattccaa atttaggtcc
     7261 tttgcttcag cgagataggt taattgaggc aggtagttga aggtgatctc tgtttggatt
     7321 ttcccatgat cgggaaaaag ttcaccggct attagtttga gcaaagtcga tttaccgaca
     7381 ccattttctc ctatgatccc tatacgatct tgctgataga cacgaagaga atcaatagat
     7441 agttctagct ggttgccaaa gctgacttgt agatttgtta tatttactgc taaattttcc
     7501 atatgtttta cactcctatt tcatgtaaaa caacaattat cgatactaaa aaagagcaga
     7561 aaaatctgtt tgcaaaaaaa ctgcatcaca tcttttccta ctctgaacga aataactatg
     7621 actaaatcac caaatctgtc atagctttca cctattctac tgtcgttcga aaaaatggac
     7681 atactccatc catgaaattg ttgtttatac atgtcttttg aatttattta gttgttattc
     7741 aaaagttcga aacgtaattt catcgatgca gtcatttttc cgacctcctt ttttattagg
     7801 ttaccacaca cgattcaaaa aaagcaatag ctactgaata gtaactgaaa accttttatt
     7861 cgaacgtagt gatcttttct ggtgctaaac gaacagactc gtaaccttct tctaccgctt
     7921 ttcctattga taaaataata actggaacat aacggtcttt atccaaacca aatgcctctg
     7981 ccaactgatc tgcttcgact ccaccaattg gatttgtttc atagccatga tcacgcgcaa
     8041 ctaacatgaa ttgcatagcc gctaagctag aatcgacttt gactacatcg ttcatttctt
     8101 ctcttgaaaa actcttgtaa taaggaatga tcgcagctaa ttgttgatct ctgacttctt
     8161 ttggcatctt ccctgattcg taagcttggt tatagatttc ttcgccatat tcgtaacatt
     8221 gcatatcgcc aaaaatcatg accattgcag aagaagtatc attttgtctc gtattgaaac
     8281 ggatcaaagg acgcaagatt tcttttgctt cctcgctttc agcgaccaca aagcgccatg
     8341 gttgcatatt gacagaagaa ggtgcagtcg tcgcttcttt gatcatttcc agcatttctt
     8401 cgtgtgggat tttgtatgtt tcatcatata cgcgaacgga tcttctacca gtcataattg
     8461 ttgaaaaatc atttttttgt tccattatta ttaacctctt tcgtttctgt tgttatattg
     8521 caaagttggg tattcaattt atctaaaagt gttagaaatt gtttcatttc tacatcgctg
     8581 aaagccgggg atagcacgga acctgtatct ttatggtcca tttcacaatg ctcgattttc
     8641 ttctgggctt tttctgttag cgctacatac acttcccggt tgttctgagg atttctctga
     8701 cgcgaaacat agccatttgc ttccaatacc ttcagatgac gagtaactgc tccttgatca
     8761 atctgcaact tttcttgcaa actgctttgt agcaatggat tttcttcttt cagtctcatc
     8821 atgatctcgt atctagtaag acttataccg atattttctt caaagatctg gacgattttt
     8881 tgatcggcta atttgatttg atataaaagg tgactaatct cttctaaaga cataatttcc
     8941 tcctttctaa taattgactc gtcaacgatt gacttgtcaa taatagaata aaaaaagaaa
     9001 aaagtcaaag aatcagctgt gtaataaaaa aaacgctctc aatagaaaag tatagagaaa
     9061 agaaattttt tgtagaatga acggaaaaaa tgataaagaa agcacaacgc taaaaccaag
     9121 attattgatt cttatcaaac tatagaagat agctcttctg cagtagaaaa ttttacaccg
     9181 ccaaaaattt ccgaaatcgc cttttgcaag aatcccgtcg aatattagaa attggatcag
     9241 tatgcttaaa cagtaataaa aaagttatga caagatgttg tcacaacctt ttttgagtaa
     9301 acggtgttca aaaacttgca tctgcggtaa taagttcaac caaacaaaaa acatgaaaat
     9361 ctgtttttgt ttggctgttc ttactacttg atgcagggca gctttttcac tacctctttt
     9421 taataaccat aaaatcctat tccttcatat ctccagccca tcggtgttag ccaatctctt
     9481 tccttagcac tcaaggtata gtgatgggta ccagtttttt catttggatt aaatagtcga
     9541 taaattggct tggaaccacc agaataaaaa cttagacctt cataacgcca accgattttt
     9601 gttaaagagt tgatctcaga ttgtgccatt gtgtaatgat ggtctccact gtaaggattg
     9661 tataaacggt agacaggttg tccgctgttt ggtgcttgcc aagcaatccc ttcatattcc
     9721 cagcctacag ttggcagata atttttttct ccggcattca atgtatataa atgttctcct
     9781 gtatgacggt tatacagacg atacatcgga gaagttgaag ttggtgctgt atcatactgt
     9841 gtcagattat aggtttcgat tacattgttc aatgtagaac cataattagg cgcagtggca
     9901 taacgacctg ttagccaagc cgtagcatct ttgtaagagt tcgtattgct tttccatgca
     9961 ccggaatagt agtaaacgcc tggctgaaaa gaagtcgtct tcaataccgt tacgttatct
    10021 tgcaatgatt ctttgtacga aggatatttt ctaaaagcgg cattcaccgt aatccattgc
    10081 ccattcacat attccgaagt aggcatcgta acagattggc cattatagct tcctttaatc
    10141 ccaaatagat tgtaattagg ggcagaagcc aaagtactgt tcccccagcc actttcaacg
    10201 atggcttgag caatcatgac tgatgcatat aagtcattgg cacttgccaa actttgtgca
    10261 gttgaggcaa tactatcaat gaacgcttgt tgagaattag cagatgagcg agcataaaaa
    10321 gcatagccag tatagttttc gaattcagac aaatctgctt gatgggtatg tgtcaatgtt
    10381 tgcccatctg tcaattggtt cgtgatttct tctgcattct ctggattgtt ctgagcttct
    10441 gctgatgtac tgtcttcggt ttgtgtttgt tctgttgttt cagttgttgg ttcttcggtt
    10501 gaaattgtat tttctgagac agtagctgac tgcaaagtac tctctgtatc gttttcaatt
    10561 cctgtttctg aagaactcga tgtctgagtt gcgacagttt ctgtcgattc ttcagctagc
    10621 actgttgtgt tggcaactgc tagatttcct aaaagaataa cgctaaataa taaattcttt
    10681 gctttcatct tttttctcct ttgaattatg aaacttttcc taaataacag tgtaactaaa
    10741 aaagtaaaag caagtcaatg tccatattta aataacattt gtttcttttt gataaatttg
    10801 ctttttctac ataaaaagac gtaaatgaag aatattcttc tccattcacg ccttaaattg
    10861 atggtcgttt gaataactat ttaacaagta attctctttg gatattatcc gttatggatt
    10921 atacttcctg tgtcgtcgga cggataatca tgttactgac agacatccgg tctggcgttt
    10981 ctatcgcaaa tgctacagca gaagctatat cttcggaggt caatccccat tctttttgcg
    11041 cttcatgaag ttcaagagca gcctttttgt cgctgatggt ttgatataat tcagtttgaa
    11101 cagctcctgg agagatgatc gtagatttga tgttattttg ccgttgctct tgacgtaatc
    11161 cttccatgat tgcacggaca gcaaattttg ttccgcaata aacggcggaa tcaggataaa
    11221 caacatgtcc cgccacagaa tcagttgaaa tgatatgccc agatttttgt ttttccatga
    11281 ttggaagtac ggcggaaatt ccatttaaca cacccatgat gttgatatca agcatatttt
    11341 gccattcatc acggtgacct tcaactaatg gagcggttgg catgattcct gcattattgt
    11401 acaatacatc gattcgaccg aacttttcca tcgctaaatc gataactgct tggacttgtg
    11461 caaaatctct tacatctgct gtttgaatat atagctcagc ttctggtaaa gattctttta
    11521 ttgcttttag gcgatcttct cggcgtgcag ctataactag tttagcccct ttttctgcta
    11581 atagcttcgt tgttgcttca ccgattccgc ttgaagcgcc catgatgaca atcacttttt
    11641 ctgataaatc attcattcta ttctcctcct gttttgaaaa atctcttgct tatactcact
    11701 atctcttatt tcatcttact gttcaaataa tccgttcgac aggtttgacg attttggcag
    11761 ggattcctgc aacgatggta ttgtctggga catctttcgt aacagttgca ttcgctgcaa
    11821 caatggcatt ctcgccaatc gttacgcctg gcagaatagt tgctcctgct ccgatccaag
    11881 catttttctt gatgtggatt ggctttacta acaagcctct tcgttctttt ggatcggtta
    11941 gatggttcac cgtgatgagg ttgacacgag gaccaatcaa tactgaatct tctaaacaga
    12001 tgccacctaa gtcaacgaac atcacttgac gattgataaa gacatttttc cctatactaa
    12061 tatgtttgcc gaaatctgta taaaaaggca gcagaacagt caccgtatca tctactttgt
    12121 cactaatgat attttctagc cgtttgcgga tatctgctgg ttcatggtac ccagtattca
    12181 gcgctgctaa aggctcttcg ttttcagctt ggatctgatg gatcacttca aagagcggat
    12241 ccgttactcg aatctcttta ttgacgattt gtttttcgat gaggcttgtc attttgctcc
    12301 ctccttttat ccttacttta taacggacgg cttatcatgt ctaatactta taaaacatac
    12361 ttaactattc cttttaacta tacttagtgg tatgcttttt taaaaacagg agggaaaaaa
    12421 tggatattcg tatactgacg tattttttag cagtagctag agaaaaaaat atcagccgag
    12481 cagcaaaatc tctgcatatc acgcaaccta ctctctcaaa acaactgaaa gatttagaag
    12541 aagaacttgg tgtgacactt ttcactcggg gctcccgaga gatacagttg acggattctg
    12601 gtcgatatct ttattcaaaa ggaaaagaaa tcttgtcgtt ggtagaaaaa acggcgaaca
    12661 atttaacaaa tgacgcaatc atctctggag aaatctacat tggcggaggc gaaactaaag
    12721 caatctcttt catttctgat agccttcatt cgttgatcaa ggcgcatcct gatatccagt
    12781 ttcatttata tagcgggaat gcagatgata tcatagacaa actggatagc ggattacttg
    12841 attttggact cgtaatcgaa ccgacaaaca aacaaaaata ccagtcattt cgactgccag
    12901 cccaagatcg ttggggactt ttgatacatc gaaatcatcc tttagcaaag caaaccgtca
    12961 tccatccgca ggaactgaaa actgttcctt tgatcatttc ccggcaaacg tcagtggaca
    13021 gtcaactagc tgaatggcta ggtttcagca tagatcagtt atcgatcgtc ggaacatata
    13081 acttattgta caatgcttct ttgatggtcg ataacgggac ttttggtgca ttagctctag
    13141 atgggatcat caatacttat gggacggaaa aaatattcat cccactcgat ccgccattac
    13201 aagcttcact gaatctcatt tggaaaaaag accagcctct ttctcctgct gctcgtaaat
    13261 ttttagatgt cctaacggag aaatacagtt aagtagagtt tttttccttc gctttcagct
    13321 ttttaacaac gaataagata agcaaaagat ccaacgatta aataacataa gtttcttaat
    13381 ttatttcttc cttttatttc tgataattcc agtaaattac tataattata aaaaaagaat
    13441 tgacaaaaca taactgtcta tataaaattg attacgttaa caataattcg tttcatgtga
    13501 ctggatcata ctaggcatga aaaatctctg aggaacatgg tttccctagg aggtttttcg
    13561 tgtctatttt tgtttggccg caatcaactg gtctagcaaa cgtgaaaacc aaatcttcaa
    13621 aaagggtgcg cgcatgaaaa tcaaaaagat ctttaatcaa aatgcagtat tggtagatga
    13681 cggtggacag gaaaaagtag ctattggaaa agggattgga tttgacagaa aaagaaatga
    13741 tttgattttt gatcgtgatg tcgaacggat atttgtcatg gaaccagaag gtcaaatcaa
    13801 gttgcaaaat ttacttaatc agattgatga acgcttttta tttgcagcag aaacgatcat
    13861 tgatcatgcg gaaactgttt tgatggaaaa gttgaatgaa catgtattga tcgctttgac
    13921 cgaccacatt gctttttctg cggagaacat taataacggt atcgtcatcc gcaacaaact
    13981 tttaagagaa atcgaagtgc tttacagtga tgaattcagt attgctcaat gggcagtaga
    14041 gtatctgaca aaagagcttg ggattccata tacttatgac gaagcaggat atatcgcaat
    14101 ccatattcac agcggacgaa gcggtcggaa caataaccat cgcagtatcc gtgaagtgac
    14161 gattgtatct gacatcatcc atttagtgga atcagaattg gaaacagata tccattcaga
    14221 accattttca ctgaattatt caagactggt gaatcattta cgactgcttc tacaacgaac
    14281 ccatgcgcaa caatatgctg ttttagacac ggaaatcgta gaaatggtca aacgaaaata
    14341 cccagaaagc tataagattt ctaaaaaaat ccgtgtgttg ctgaccaaag aataccagct
    14401 cgcgatcacg aaagaagaac tgggttactt ggccatccat atcgagcgtt taagaagcgc
    14461 aatcgtacaa acaaatgtta acaatcatga ggaggaaaaa aattgaaagc atatctacaa
    14521 cgaatgggac gttcccttca acttccagtt gcggtcttac ctgctgctgc tttactagta
    14581 gggatcggaa actggtgggc atcttatagt aacgacattg tcgctcattt tttacaagct
    14641 ggcggtaacg cagttttagg tcaattacct ttgctgtttg ccgttgggtt agcactaggg
    14701 atgtcagtgg acaaatcagg tgctgctgcc ttggcaggtt tggtcgcatt tgaagttcca
    14761 gtaaatgttt taaaaactga ttcagtagct actttattga atatcaaacc agaatcagtt
    14821 gatccatctt ttgctcagat cagtaacgta tttattggta ttattgccgg attgattgcg
    14881 gcagctcttt ataatcgttt ccacgaagca aaattaccga tggctttatc tttctttagc
    14941 ggcaagcgtc tagtgccaat cttggctgcc tttgtcatgt tgctgatcag tgcagtgcta
    15001 ctgctcgtat ggcctccggt ttactctgct ttagtttctt ttgctaaatt cattttgagt
    15061 ttaggctggg gtggtgcagg tctttatggc ttcttcaacc gtttactgat ccctacagga
    15121 ttgcatcaag caatgaactc cgtgttctgg tttgacgtag caggaatcaa tgatattggt
    15181 aaatttttgg cttctgaagg aacaaaaggc gtaacaggaa tgtatcaagc tggatttttc
    15241 ccaatcatga tgttcgggct tccagcagga gcatatgcta tttacagaaa tgcacgtcca
    15301 gaaaacaaag caaaaacagc ttccttgatg ctagcagcag cttttgcttc attctttact
    15361 ggtgtgacag aaccacttga attttcattt atgttcgttg cttggccatt atatgtcttg
    15421 catgcaattt tcactgggat ttctttagca gtgagtgcat tcttccattg gacagcagga
    15481 tttgccttta gtgccggatt tgtcgattac ttcctatctt tgaaaaatcc gattgcgaat
    15541 cagccattga tgttgatcgt ccaaggatta gtaacagcag tgatttacta ctttggcttt
    15601 aactttgcta tcaaaaaatt ccatctgatg actcctggcc gcgaggaagc agatctttca
    15661 gatgacgata ctgcaacgac taattcagac aataaatatg cggcacaagc aagcaaaatc
    15721 tacgctgcat taggcggagc cgacaatgta acttcgatcg ataactgtac tacacgcctt
    15781 cgtttgcaag tcaaagatac aggcctgatc gatcaaaata aaatcaaagc cactggcgta
    15841 cctggtatga agatcatcga cggaaaaaat gcgcaagtca tcgtaggtac agaagtacaa
    15901 ttcgttgcag atgagatggc aaaactacat ggtggtgctg cagcacgacc tgcacaaaca
    15961 aacaccgtgg ttaaaacaga aacatttgcc ggtgaaacga tcgaacaaga tatttacgct
    16021 atcgcaaatg ggaaactgat tccaatcact gaagtttcag atgatgtatt cgcggaaaaa
    16081 atgatgggtg acggctatgc tgtattacca gaaaatggag aaatcttctc tccaatcgct
    16141 ggtacgatca caaacatttt cccaacgaaa catgctgtcg gaatccaaac agatgctggt
    16201 atcgaagtct tgcttcatat gggcatcaac actgttgact taaaaggcga accattcact
    16261 ttatatgtag aagaaggtca aaaagtcgca agaggtcaat tgattgcttt agttgatctt
    16321 gccgctattc aatctgcagg caaaaacacg gatatggtcg ttgtattcac aaatggcgac
    16381 aaagtccaaa gcttagaaat cgaacccgca cgtgatgtaa aagcaaatga taaaatcggc
    16441 tctgtttcca acaaagcctg agccatcgtc ttccccagac ttttttatcg ataaacaaac
    16501 aggagctgag acaaaaatct tgtctcagct cctttttccg aataaaaacg gcgttctcct
    16561 gccaactccg cggtaataag tccagctaaa cgaaacatat gaagagctat tttttatttg
    16621 actcttctta ttacttgatg cagaacagct ttttcacaaa atttttcttc atactcaaaa
    16681 ctaatcggct ttttcacaac ctctttatac attattcctg atccaatatt tcttttaatg
    16741 ctgcttcaag agaagttaat ggttttccca atactttttc taaatcatca gaggaaatag
    16801 ctaactgatc ctttttaata tcatgttgga tcgctaaaaa catgtcagct gcttcttgag
    16861 ggaatccggc ttcttttaga ttttcgacaa acgctgcatc acttgcttca ataatttcta
    16921 actctttacc tgtcgcacgc tctaatgcct tggctaattc ttcatagtca gttagattgc
    16981 cggataattc taagatttct ggagagtcac tttctactag tacttttgct gcagcttctg
    17041 catattcacg tttcaatgcc caacctgttt ttccatttcc tgcagcataa acgaattgac
    17101 cagtttttaa agcctgccca atgataggta attcattctc tacataccaa ttattccgta
    17161 aaaatgtatg ggaaatacct gaatccttaa tcattttttc agtgaattgg tgatctggcg
    17221 ctaatacact gatcgagtga tcggcatctg caaaacttgt ataagcgata taagataccc
    17281 cagctgcttg tgctgccttc actacattct tatgttcggc ttgacgattt cctggaacgc
    17341 cagagacaaa aagcaatcga tctattcctt tcaacgcttc tttcattgag tctaaatcat
    17401 cataatcacc aatacgtata ttaaatccag cttctttcag tgcttctcct ttttcttcac
    17461 tacgtactag tacatagatt tcattttgtg gaaccatctt ttttaagaat tccagcgcat
    17521 aaccaccaaa acctccagtt gctcctgtta ctaaataatg catatttgcc actccctatt
    17581 ctttttattt gttaagattt acagctgtac atttataaat tacaccttta tcataaagag
    17641 tgtggtaaga taagtcaagc aaaaaaaatg aaaggatgac aactgatgaa gtattctctg
    17701 caatttagtg atgcaatcca tgtacttgcc tatattgaaa tgtttcaaga tacccgatca
    17761 ctttctagtg agatgattgc cagtagtatc gaaacaaatg cagcaaatgt acgtaaaatc
    17821 atgagtcagc tcaaaaaatc cggtttgatc tttacaaaaa ccggaaaacc gcagccttcc
    17881 cttgccaaaa gtccagatca gatttcttta ctagatgtct atcgcagcat cgaaggtaat
    17941 acacagctta tccaagtcga tccaaaaaca aatccaaatt gcgtcgttgg tgcgaatatc
    18001 caagaagctt tagaagaaag ctacgctcgg ctgcagaaaa aggcagaaga agaaatggct
    18061 aagatcacac ttgatagtct gatacataaa atagccgttt tggaaaaaga aaaaagacca
    18121 gaaaacacag gcctcgtaga gagattttta taattctctc tactgtgcct gcatttttct
    18181 gatcggaatc gtctacataa attcttttat tctccggggg acaaaagcct tgtcatgccc
    18241 ctttttcctc tctaatgctc aggtcaaagc gctactttca cgacctctat attatcatgg
    18301 tttattgact accggtatcc agatttctcc catatatttc ccgttggtaa ctcccatttc
    18361 gactacagca tttggacccc caacataggc gtaatcttct acttctctta aaacatgccc
    18421 aaaggccgta ttcgtcaaat catttcttaa ttcttcaggc gattctgcta aagcgcttac
    18481 aacaagatac gttccttttg ggaatgggat gattcgcgta gtgtttggaa catcctgact
    18541 cgtttgaaca ccgacatagt acatcatttt cccgttatag ggttcgttga ctgtaaagaa
    18601 ataatgattt tcagcagctt gtttcaatgc atctattgtt ccattaccga taactttttg
    18661 ctcaaatgct tgtttctctg cagccaaacc gacaaaatcc gtattgctac tcttcaattc
    18721 cacaccaata cccgtcaccg taaaatctgg tttttcttcg atcctatact ttgccatttc
    18781 tcccaccctt tctattatat taagttcatc ttacataaaa ttaaagggaa atgacacgat
    18841 tacgctcttt tttctaggga tatttttatt ttttaactat ttttttgctt tcactgcaat
    18901 ccaaatctca ctgtaaacat tactgaaatc ctctccccat tttgtaaaag agatctcggg
    18961 agcttcgact aacccataat ctgaagaagg aagccattct gcatagattt tcccccaagt
    19021 atcttgtaaa gtttggggaa atggcccttt attaggaaaa atggcccaag tgtgttcttc
    19081 tatagcaagc atttctaaat cagcgtacgg attttctttt gtcgtagcaa agccaatcat
    19141 gtgcatcaaa ctgccctttt cttccaagcg gtctccatca aatccataag aaacgttgat
    19201 tacttgattt ggatataaat ctcctaactt atgcatctct tccctttgag tctccgtgat
    19261 cgtctgcgct aacttttgta tttcttgatt gactccttca aatttgacag gaactttttt
    19321 cgccacacct gccacataaa actgttcttt cttttcgata cgaaattcca tcgattttcc
    19381 tcctctgaca tcaataaaaa atgtcaagcg tggaaaagat ttttgtatgc cgtatctgct
    19441 gatttctgaa ggcagatatc ctgaccaatc acgaaaagct cttgaaaaac cttcgactgt
    19501 ttcatatcca tatctaaacg ccgtttctgt cactcttgat ccatctagaa gatcgcgatt
    19561 agccaaagcc aatctacggt ttttgatata gtccattagc gacatccctg caataaacgt
    19621 aaagatgcgt tttaattgat attcagagat tcctgtattt tcggctatta ttttatagga
    19681 aagtccttct gtcaaatgtt cttcgatgta atcgatcaat tggttcagat ctttaagcat
    19741 atttatcttc ctccttgatt gcctttttat catattatca aagaaagtca attacttgat
    19801 gaatcaggaa ccaatttagt cagatgtaga aaatgttgta tggatctaaa gaaaattctc
    19861 aagcagcgtt tcgtaacgga taattggtat tatctgccta tctatgtttt acctttagaa
    19921 aaataaattt tggggaagac agattctaag taaacaaagc ggtaaaaata tcttttattc
    19981 ccttagttaa tccgcttact acctactgta caaagcaaat tgttgttcaa actgctgatc
    20041 agaacgctgc ttggattttt cttt
//
LOCUS       DAIGSZ010000055        19788 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.055, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000055 DAIGSZ010000000
VERSION     DAIGSZ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.055"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            109..303
                     /locus_tag="NOB31_002062"
     CDS             109..303
                     /locus_tag="NOB31_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974261.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            572..871
                     /locus_tag="NOB31_002063"
     CDS             572..871
                     /locus_tag="NOB31_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974262.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(968..1402)
                     /locus_tag="NOB31_002064"
     CDS             complement(968..1402)
                     /locus_tag="NOB31_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0974263.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1634..2344)
                     /locus_tag="NOB31_002065"
     CDS             complement(1634..2344)
                     /locus_tag="NOB31_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCI0974264.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2334..3194)
                     /locus_tag="NOB31_002066"
     CDS             complement(2334..3194)
                     /locus_tag="NOB31_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HCI0974265.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3199..3837)
                     /locus_tag="NOB31_002067"
     CDS             complement(3199..3837)
                     /locus_tag="NOB31_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HCI0974266.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3852..4151)
                     /locus_tag="NOB31_002068"
     CDS             complement(3852..4151)
                     /locus_tag="NOB31_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0974267.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4194..5678)
                     /locus_tag="NOB31_002069"
     CDS             complement(4194..5678)
                     /locus_tag="NOB31_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCI0974268.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5698..6159)
                     /locus_tag="NOB31_002070"
     CDS             complement(5698..6159)
                     /locus_tag="NOB31_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0974269.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6177..7244)
                     /gene="ulaG"
                     /locus_tag="NOB31_002071"
     CDS             complement(6177..7244)
                     /gene="ulaG"
                     /locus_tag="NOB31_002071"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HCI0974270.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7462..8232
                     /locus_tag="NOB31_002072"
     CDS             7462..8232
                     /locus_tag="NOB31_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCI0974271.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8505..9332)
                     /locus_tag="NOB31_002073"
     CDS             complement(8505..9332)
                     /locus_tag="NOB31_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0974272.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9900..11135
                     /locus_tag="NOB31_002074"
     CDS             9900..11135
                     /locus_tag="NOB31_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCI0974273.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12134..12394)
                     /locus_tag="NOB31_002075"
     CDS             complement(12134..12394)
                     /locus_tag="NOB31_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCI0974274.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12421..13722)
                     /locus_tag="NOB31_002076"
     CDS             complement(12421..13722)
                     /locus_tag="NOB31_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0974275.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14014..14472)
                     /locus_tag="NOB31_002077"
     CDS             complement(14014..14472)
                     /locus_tag="NOB31_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0974276.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14485..15816)
                     /locus_tag="NOB31_002078"
     CDS             complement(14485..15816)
                     /locus_tag="NOB31_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HCI0974277.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15827..17269)
                     /locus_tag="NOB31_002079"
     CDS             complement(15827..17269)
                     /locus_tag="NOB31_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0974278.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17256..18020)
                     /locus_tag="NOB31_002080"
     CDS             complement(17256..18020)
                     /locus_tag="NOB31_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HCI0974279.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18124..18999)
                     /locus_tag="NOB31_002081"
     CDS             complement(18124..18999)
                     /locus_tag="NOB31_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0974280.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19254..19338)
                     /locus_tag="NOB31_002082"
     tRNA            complement(19254..19338)
                     /locus_tag="NOB31_002082"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19302..19304),aa:Leu,seq:caa)
     gene            complement(19356..19427)
                     /locus_tag="NOB31_002083"
     tRNA            complement(19356..19427)
                     /locus_tag="NOB31_002083"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19393..19395),aa:Gln,seq:ttg)
     gene            complement(19437..19509)
                     /locus_tag="NOB31_002084"
     tRNA            complement(19437..19509)
                     /locus_tag="NOB31_002084"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19474..19476),aa:His,seq:gtg)
     gene            complement(19571..19655)
                     /locus_tag="NOB31_002085"
     tRNA            complement(19571..19655)
                     /locus_tag="NOB31_002085"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19619..19621),aa:Leu,seq:caa)
     gene            complement(19676..19746)
                     /locus_tag="NOB31_002086"
     tRNA            complement(19676..19746)
                     /locus_tag="NOB31_002086"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19712..19714),aa:Cys,seq:gca)
BASE COUNT         6280 a         4092 c         3077 g         6339 t
ORIGIN      
        1 actttcaaat tgattctttt tatttatcat aaagatatag atacataatc attttcactt
       61 acatatattt gaatattaac taaaaacagc aagaaagaag aggatcaaat gtattatgta
      121 gaagtaaaaa caaaaggcgt caaaaacaaa caatatgtga aaggtatcag taacgaatat
      181 cctttacttg gttcatggaa agaagctgct cctttttcca aaccatgtgc cataaaaata
      241 aagaacgagc tagaaaaaga actgacttgt ggtaaagctg ttgtagatat catcgaaaag
      301 taaatccaat gtatagaaag gaagatcaca catgaaaagc gacgtacaaa ttgctaagat
      361 tatagaatta gaagaagaag acgcagtgtt gacaattgaa aaaaaataaa tgtttgtata
      421 ccatatgatt atttcaatat gtatcctgga attggagatc tcgtagagct atatcaagat
      481 gaatcaaata tacttgtcat tcatcatgaa atatagagac ttataaaatt gtttattttt
      541 ataatgtatc agtatagaaa ggaaataaaa catggattat actgttgaat ttgacagtga
      601 actacttaag caatttccac aagaagaaca tttcatgtat aaagaagcaa tttcccacaa
      661 agtgacagag tatttggagc ataatttttt tcgtataaag ccagtgcgta ctcgttcggc
      721 aaaaggaata tacgagatga aagtcaaaat taataaaaaa aattatcgca tagcatttgc
      781 tttaaaaaaa aatcatgtgt tcatttttta tattagttcg aatttgcaaa aaattgtatt
      841 tgataaagag gtgagtaaaa aaataaaata gctgagcatt ggaggataga ttgagtgata
      901 ctaagtctat cctcttgttt ttctaaagaa ctaagctaga attttttctt ttgtacgtta
      961 ttatatgtta tttgtcatta ccaaaaagca ccttttttct tctagtatct atgacataag
     1021 aaataccacc catttccttt acttgaacaa atcctactga ttcataaaat ttttttgttt
     1081 tctcagtatc atctgtcaat aattcgattt ggactggtcc ataactagtg atcttctcca
     1141 aagcttcatt caaaagcact ttgcctattc cttggcgctg atacctcgga tgaatgagga
     1201 tatcttgaat aaatgcgatc gtcgcaaaat cagtgatcca acgaacgatt ccgataatct
     1261 tcccttcccc attacgcttt atcagagatt cagattgttc aaatgctcta gctaaccttg
     1321 cagtgtcttt tgtgtaattc gtccaaccaa cgctcttata taattcagaa atctcatcga
     1381 tcataaggga atcaatattc atttttttct tcctttctta tacaattctc cctctaataa
     1441 tacagttctt tgactattta atctatcaca tataactctc ctgtaaagat tctctcgatt
     1501 ccttaaaatt cctctttcct tttagaatgc atactttttg ataaataaaa aggttgtgat
     1561 aaattttctt cacaacctct gtttctctct atcaagtgtt atcttttaat tttctaccct
     1621 taccctagca tctctattgc ccgtagtatg catactttcc atgtttgcga aaataatgtt
     1681 tatctagtaa atattgcggg atttcacata tattggggtt gatcagctcg ttttctttgg
     1741 ccatcagaca aatttcatct aagatcaaac tgttttctac tgctttcata ggtgaatccc
     1801 cccatgtgaa cggtccatgt ccatagacaa gtactccagg gacttcgttt ggatctaatt
     1861 ttctttcctt aaacgtctcg acaatcacat tccctgtatg aacttcgtaa gcttctctta
     1921 cttcttcttt cgttaattgg cgtgtacaag gaaccttacc ataaaaagca tcagcatgag
     1981 tcgtgccata agctggcaaa tcgcgtcctg cttgcgccca catgacggag tgcgtggaat
     2041 gagtatgagt aatagcagtt atatcttcaa aagtttgata caaaacaaca tgtgtgggga
     2101 gatctgaaga tggttttaag ctatcttctt ctattatatt tcccgacaaa tctgttacca
     2161 ccatttgatc tgcttgcatg cattcatatc tgacaccgct tggcttaatg acgatgactc
     2221 ctagctcacg gtccacttca ctcacattgc cccaagtcaa tttgactaat ccgtatcgcg
     2281 gcaatgccag atttgcttca aggacacgtt gcttcattgc tgcaattttt tcttcacaag
     2341 acatcatagc cagcctcctt caatttagaa cttaagtagt cttttgcctg ctggatttct
     2401 cttcgaaagt cttggctttt ttcactccac atttcaatca gaaatgttcc atcataatct
     2461 agacgtttca aatgtcttaa taatccaaga aaatcaacac aaccgctacc aaaaggaaca
     2521 tcacgaaact ggcctgaata ttcttttgtt acagggtaag tatcttttaa gtggatagca
     2581 gtgatataat cgatcccttt ctcaagttct cgagccggat tattttccgg ccatgcggac
     2641 aaattgccta ggtctggata tacttgtaga aaaggtgaat gaatctgttc tttgatttct
     2701 aaaaattttg aaatggagtt cataaatgga tcatccatga tttccacgga aagaatgatg
     2761 ccatatttag aagcttcctt tacgctttct tttattcctt cgataaagtc ttctctggaa
     2821 ttcattgatt tctcttcata ataaacatcg tatccagcta tttggattac tttgacgctt
     2881 agattatgcg ccaaatggat tgcttttttc attagttgtt tcgctgcttt tttcttttct
     2941 ggatcagcag aaccaaacgg aaatcgccga tgcgcactta aacaaatcga atggatacgt
     3001 acaccggagc tgaacatctc ttctctcagc tcagctatct tttcttcaga ccaatctaat
     3061 cgtgctaacc gctcatccgt ctcatcaatc gacatctcga taaaatcgaa gtccatttct
     3121 tttacaaggg aaaaacgttc tttccatgaa atatctttgg gtaacgcttt ttcataaatc
     3181 ccaatttgag ccatttcctt acccccagat acgaatgatc tcatctttga agttttgtgc
     3241 ggccttcatc ggatcatttg ctgctgtaat accacgacca gtgataaagg tatacacatc
     3301 gatcccttca aataagtgta atgtgtgtgg atttaatcca ccagttacag aaacattaaa
     3361 gcctagttca atcagttttt tgatcttcga taaatctttt tcaccccaag tttcaccaga
     3421 taacagcgca tcacggcttt gatggtagat tacctgccgg ataccgatgt tatgccaatc
     3481 catggcttgt tcaaaagtcc aattgccgta gagttctact tgcaattcac ctatttcttt
     3541 ttgtgctgcc tccatagttg gaatcgttgc acaacaaatg actgtcatcc agtctgctcc
     3601 tgcttttgca acattactcg ccactgttcc tccagcgtct gcacatttcg tatcagcgac
     3661 tagtttttta tctgggaaca tactgcgaat acagcgaatc gctttttgtc cttcctgtaa
     3721 gcaaagaatt gtgcccactt caataatatc tactacatca ccaactttca taacatctcc
     3781 taatgcatgt tctaagtcat tgtgatctaa cgcaatttgc aaattcggcc tgctcatctt
     3841 agttccttcc tttacttgtt tttttggtac cactttgttt cagcaaattt ttcactgatt
     3901 tctttgactg acatcacatt tttgataccg ataactgtaa ctcctttttt ctctgcctga
     3961 gtaaacatat tcaaaaaatt gactggcgta aaaactacat cgtattggcc agctgaactt
     4021 tttccctctg aaatggcaca atgatggatt ttggtaattg gtacgtttag ttctttcatt
     4081 gctttttcca cacttctcat catcatcaag cttgttcctg atccatttgc acacgatact
     4141 aaaattctca tcttaatccc tccattatga gtgttgtcta atcagatttt cttttatact
     4201 ctctgctttt ctgcatatgt gtcatagtct tctacaatca aaaaataacc atcaggattt
     4261 ttccgatatt gtaactgcgg aatagccaat aaaccaatga caactacggc aattccagca
     4321 taacctagga ctttcatgat tactgtaaac aatggccaag ctgttgccca gtcgaacatc
     4381 ccgatataac caccgtatgt tgacatccca atccatgtag cgaataatgc tgaaccgcct
     4441 acttgtatga ttcctgaaag aaacgggaac aggcaagcgg ctttgaatcc acctcggtta
     4501 ttggcataaa ctgctataac ggcattatca aagaacaacg gaatgaaacc ggctatgacg
     4561 atcgttggtg atttcaataa aatcagtaaa ccaatcatca aaaactgtcc caaagcacca
     4621 aacaagaacc caatcgttac cgcatttggc gaaccaaagc caaaagtagc agctacgtca
     4681 attcctggaa cagctcctgg taaaatcgtg tttgagattc cttggaaaga ttgagttagt
     4741 tcatcgacga atgtccgaac acctaattgc aagatcgcca gatataccgc aaaatttaaa
     4801 gaagtcgtca taatgtagaa taagaaactc tgcccttctt gcatgaattg cgcttgaatc
     4861 aaataatctt tgcctagtac aatcagaatg atcccaaaga aaaatagcat gagtaacgaa
     4921 gtagcaacca tattctcatt gaaaatcgac aagaatcctg gtaatttgat atcttcaatt
     4981 tttttgtctt gcttgattga tctatttttc ttttcatccc gctttttcat ccactcagct
     5041 aattttgcaa atataaagat tccgaacatt tgctgatgtg ccactgcaaa tccggcacct
     5101 tctgtcaatt cctgcgtgat tcctactgtt aagttagaag ctactgtcca ataacaacct
     5161 aaaatcagtc ccataaaaat caatgcttgt atcctaccta gatcaggaaa gcaaaacagt
     5221 aaaatccaaa aagcggtagc tgcttgttga acctgaacgt ttccggtagt gaaaacggaa
     5281 cgcagtttcg tatatttctg aaaacggact aataagatat ttaaaacaaa tgcaatcagt
     5341 aataaaatca tcacatctcc aaaggtacgg ccaaatgtct ccattaatcc agcatccaca
     5401 gcattttgtc caaaataagg atctgtaacc atggcatcca aattgaaccg ttcctttagt
     5461 ccaaccaaga ttggccgaaa attattgacc aaaccaccag agccaacagt caaaataaag
     5521 taaccgaccg ttgcctttaa gaatccagcg atgcattcat gaagcgggcg tttcagcaaa
     5581 atatagccta ataacacgat aaaaccaatc aggtatgctg gctgcgtcaa gatatttgtt
     5641 gcaaaatacg tccaaatgct taacaaaaat tcccccatct tttttctcct ctatcaatta
     5701 attatattct gccatcacaa cttggtaatc atcgatggag ttcgtagaga tgagacgctc
     5761 aaccaatcca tctgtcatta ataattcgga taatttttgg atattttcta gatgttcttc
     5821 tggatctttt gctgcgagtg taaaaaacaa actagccgtt ttctcctcat tctccccttc
     5881 actttcaaaa cggattggct gtttcaactt ggtaaatgaa atagctgttc caaaaacacc
     5941 atcacttttt tctgaagaat gcggcattgc tacttgaggt gcgatcacaa tataaggacc
     6001 gtatttttct acacaatgga tgatctcctc cacatacgtt tcatcaataa tttccttatc
     6061 gatcaataca agacagcttt cggcgatagc ttcacgccaa tccgtgattt ctttatctgg
     6121 gtaatgaatc aattgatggt caaaaaagta tttcagcaag aaactcccct tctttcttat
     6181 aaaaacgacg gaaacggtgt atcattttca atcgagaaga catcttcaaa tcctcgataa
     6241 aaattaaact caagatcatc tttgtttgtc ggatagatga atttcccgcc tacttgccag
     6301 atataaggtt taaatccata cttcaggcga tcctttttga atttccaaat ttcagtgatc
     6361 tcttttggat cagccataaa attagaccaa atatcgtagt ggacaggaat cactactttt
     6421 gcattcaatg actccgccat gcgcagcata tcaacagaag taactttgtc tgttatccct
     6481 cgtgggtttt caccataggc ccctaaacag acatcgattt tgtgttcatt accatgtttg
     6541 gcaaataaat tggagtaatg tgaatctcct gcatgataaa gattccctcc tgatgtttcg
     6601 aataaatagt ttactgcaat ttgatccatc tcctgaggca tttttccttt taatacctct
     6661 tctggatctt cacaagtgac caacgctgtc cgatcaaacg cttctaaagc tactacattg
     6721 atgtctttga ttttgactgc atcacctggc tttactgtaa tcgttttttc ttcaggaatt
     6781 ccccattttt gccacgtgcg aaccacttct tttggcccaa tgaatgttgc ttcaggacaa
     6841 ttttgatgaa ctgctgcggc tgtatggata tctagatgat cggaatggat atgtgtaacg
     6901 attaaagcgt ctacattttt tatcgcaaaa ggatcgatta cgaaaggctg agtacgtaaa
     6961 ttaggctgca tattttgaac gccactcata cgcatcatct gatggccttt tttcatcatg
     7021 ccattcccat gactacgttt tcccgtccca caccatagat cacataaaat attcgttcct
     7081 tcatgacttt tcagccaaat tcccgtacag cccagccacc acatagcaaa agttccagga
     7141 tccactactt ctgtttcgat ttcttcattc aagtatgtgc cccactcagg aaatgtttct
     7201 actaaccact tttcttttgt tacttcattg acagttttac tcatttgctt gctcccccca
     7261 tatcgttgtt ccaacttaca agtaaatatt aatgtgtatc agcatccatg aaaacccttt
     7321 tatatgaccg tttgtttttt atatgatttt ctttcagtaa tcaatgattg tttcagtata
     7381 ataaagacag atatgaatgt ttaaatgaac aactagtcaa ataaatccat ggatcaagat
     7441 gtccctcagg aggcaaaagt catgaaaaac tcacttgtca atattgaaaa acgtcaaaaa
     7501 gaaattttgg aactgcttca gcagactgaa caactatcaa ctttcgaatt agctgaatcc
     7561 cttgatgtat ctattagtac gatacgaaga gatttaaatt tattagaaga aaaaaacgag
     7621 atcatacgca attacggtta ttgttcttat aattacaaaa accagactga ttttgatcaa
     7681 tctggtcctg aaaggattaa acaagcgatt gccagagaag ctagtaaata cattaacgat
     7741 tatgatacgc tgtttatcaa ttctagctcg actgcgttga aaacactgga ttttcttcaa
     7801 tctaaccatt tgacagtcat tacaaacaac gtgaaaatca attactctcc gcacaaagat
     7861 aattgtagtt atattttaac tggtggagag atgcgctttc caaaagaagc actagtgggc
     7921 gacatcgcat taaatacgat ttcttcagtc aatgcagaca tttgtatcat tggctgtagc
     7981 ggagtcgatg tagtacatgg ggtcacaaca aagatattaa atgaatcaac gatcaacgaa
     8041 atgatggtca acaagacaat caaatgtaag attttagtcg ctgatcatcg aaaaatcgga
     8101 ctgacatcaa agttcaagat tgctgatatt tcagtctttg attatttgat cactgataaa
     8161 ttttgttctg aaaaagtatt agaggagatc agaaatacgg ggataaaaac cattcaagta
     8221 gattcatttt aagaaccagg acgtaaatat gtaaatagga ttatcaaaaa aatgaataac
     8281 aaatttatcg ataaatgaaa aacacgctac gctcaaattg ataaaggaat cccaagatgt
     8341 atccatccaa tcgataccat cataatctat tgcttctttt ataaccgtta tatgttgcct
     8401 aaataggaat caaacaatat cgaaaaaagg aggtatgaca aaagtcacac ctcctttttt
     8461 cgaataaacg gtattcaaat cagaacactg atttcacaac cactttattt caggtcgttt
     8521 tcaatcacct ttaccgcgta atcatttccg ttgaaacgcg ctattttttt tgcgtccata
     8581 tatctttcta aataatcatc ttctcctaat tgcttatggc aagaagcaat ttcataaagc
     8641 aagtattcca atgcataagt cgatttatgt ttcttattat actcaatacc cttctcacat
     8701 aattggattg ctttatcata atcctcgatt ttacggtaat aggtggcgat atcataatat
     8761 acaatgcaga ccatcagatt atcaaaatca gtctcactca atattttaag tgtacgctcc
     8821 acataaactt tcgcaaaatc taattctcct tttgacaagt agatcattgc cacgtttgca
     8881 gctgcttgta agtgatggat atctgtttcg gtcgtttgtt ccaacacttg attaaaataa
     8941 aataatgctg catctggttt tttcgcataa agatgatcaa gcagtccttg ataaaataaa
     9001 atttgattta aaagatcaga attacttact ttttcctgat cgatcgtttg taaaatttta
     9061 taagattctt ggtattttga tacagaattc aatgattgaa tctcatttat ttttttcctg
     9121 attttgtctt cttctgtttc tactaatata tcggagatct cgacattcag ctttttgcaa
     9181 agcgcactta agatattgat gcctggcgac atattcttgt tttcgatatt gctgacagtt
     9241 gcttgttcac aaatgccttc tgctaattgt acttgtgtta accccttttt ctttcggtat
     9301 tcttttagta atgctccatc tactttaatc aaaacaattt ccttcccttt aaaaaattat
     9361 ttctccttta tatcatacac aaaaaaaagt tctaaacaac caaaaatgtt tagaacagaa
     9421 taaaaatttt aattttaaaa taatattcaa attaaacaac tggcgtatct gctccttgat
     9481 ttctttttgt gttatctgaa taattatcgt ttacagttat aacacatagt gaaaattgtc
     9541 atggcgagaa agtctaagaa tatttttaaa cataactatt tctttcttac gtgtgtataa
     9601 tgacgacagc acacctatca attaatataa ttattttatt tttttatgtt ctcatgttta
     9661 tttttaatga cacaacttct cgtatttatc tggcacaaca tataaatcga tcaaaaaatt
     9721 gttgcgtgtt tttttgaaaa ttggagtttc aacttgatta caaaatttaa atttagaagt
     9781 tgtgaaaaca gcgagagaca gtttaatatt caaaatatac ataggctact cgaacgctgt
     9841 gttttttagt atactagtaa gaaacgaagg gatagactca ttccaataag gaggatttca
     9901 tgaagacaat tctttttgct cctgcagtat tcaatttagc tgagacaaca cgaatgattg
     9961 aggttgccaa agctatgaaa gaccgttatt actgtgtatt ctttggcttt tctaaaactt
    10021 ttgctccttt gatcacagaa agtggctttg agtatcattt actagcgccg atccttacga
    10081 aaaaacaaga agaacaaatc ataaaatttg accagttgcg tacacttaaa aaccctttta
    10141 ccaaagaaat ggttgcctct cgtatcacta gtgaacagag tctgattgct aagtttgagc
    10201 ctcgactgat tgtgacaggt tcgaatgtga caattttttt atcggcccgc aataaaaaga
    10261 ttcctttagt atatgttaaa ccctatgctt tgagtgaacc tttttttcaa tcagagcatg
    10321 cgctgatgcc ccacgagtta cgtttcttcg gccctttaag caatcccctt tggcactgga
    10381 caaaaaagcg tatagtaaat acccgatgga tccccaatgc cttcaaacac gctgcacaaa
    10441 aagaaatgct tcctttacca aaaacaagtt tacaaatgat ggatgctgat ctaaatctca
    10501 tcacaacgcc taaactattt ttggaagaag aacagctgcc ggaaaattat cgaatcgttg
    10561 gtccaatttt tgctaagctc agtacttcct tgcctgaaga agtgctaact tttatacagc
    10621 gaaagcaaca agaaagaaaa cgtattatct atttcgcaat gggtagttca ggcaatccgc
    10681 gtatgttacg caaaattttg ttcttcttac aaaaacaacc ggatctagcg gttattgcac
    10741 ctattgacta tctgcttgat gacattcaat ctgactcaga agatctttta ataacagaat
    10801 atctgtctag tcatcttttg catgaattca ttgatttttc ttttatccac ggcggggaag
    10861 ggaccgtcca aactgcctgt gaatccggca aaccgtttat cggtgtgggg atgcaatttg
    10921 agcaaagctg taatattgac tattgtgtaa aatacggaaa cgcaatcgcc ctcacaaaac
    10981 cagtgactga aagaaaactg cagattgctc tgcgcgaagt ttcttcaccc aagattcgtc
    11041 agcaggcacg cacgctgcaa gccgtttttc caataaatgg tccacaacaa gcaattcaag
    11101 aaatcgaaac cttcctgagc aaccacccaa tatagtttca agtagaaaaa gcttttttaa
    11161 tagagactca tcagtaattt cgctattcga gacccagaca gtgaaaatac aaaaaaagta
    11221 aatagtggat tgaaaagtta gagttactta aattacggtg tctaaaaaac acaaaatcat
    11281 ccttaaaata aaagatctga cgctatccaa atgagcatag gtagcgtctg ccatttattc
    11341 ttagtcaaat tctttgacac ctttctctgg ttggatcatc tcaacgtttc ttcaaaagaa
    11401 agaccataat aattaggcaa atacattttc ttaaaatgtg tcatatagat ctagaagcat
    11461 cgctttgtag agatttgtgc cgctagtccc ctcaacaatt actaaatcaa atgtaggatt
    11521 taccacttta tctttgataa tcaacctccc tcttctgttg agacaatgat ctcgcaatcc
    11581 gatgcatact cctatataaa ctgccagcaa tccccacata ttgagtagat catgtcagaa
    11641 tgttctatgt cgtcagcaac gatacactaa aagtcacgtt caccatgact gattgctatt
    11701 cccagcacaa ttatttctat acacgtttca tgatttgaat aaacactcac atcatacata
    11761 ttaccattca tacaccatac tgcagcccct actatatggt tgtaagctcc caaatctata
    11821 tttgacttga tcactttggt agtagatcta ctaattctaa atccattgct gataaaattt
    11881 ccattttttc ctccttcttt ctgccaaaac agttaaaaca ataataatct ttatgtaaaa
    11941 aagggctgtg acaaaagcct tgtcacagtc ccatattccg aataaacggt ggtcaaaagc
    12001 ttgcatctgc ggtaataagt tcaaccaaac gaaaaataag ccaacatttc acaaaaattt
    12061 aagaagcaat tttcgtaaat ttcttcttat ttcttgaagc taaccacttc tgttacaacc
    12121 acttttagaa catttaaagc ttcgatgtga caaaccatct atgctgctcg atcataaaat
    12181 tgatagcaaa aattccacaa agtacatatg tcccccatga aaacaaaaca ttcatatgcg
    12241 gtacaatgat ctttggaaga atcacgatca aaaatgatgc cagtgcccaa atccatcgat
    12301 tgatttgaat atgatatgta gctagcatat tcaatataag gtgactagcc gttaataaaa
    12361 agataaaaac aaaaaataaa atcagccaat acattgtttc ccaccttcta aaaaccaaac
    12421 ttagacagtc tggacttcgt tttctccacg actttgttca tctgacagca tctttttatc
    12481 ataagctttt acaaatggat aatagataat aaatgctatc aatgtgttga tcatgatcaa
    12541 gataacaaca cgccagtcat ttcctgctga aagataaccg ccgattggag ctggtaatgt
    12601 ccatgttggc aaaacagtaa atctattgac catttctaat ttgactgcaa aataactgat
    12661 aatagtcaaa actaaaggaa ctaagttgaa cgggatgaac atgtaaggat tcaacatcat
    12721 aggagctcca aaaattatgg gctcattgat attgaagata ccaggaataa tagaaaaacg
    12781 accaacctct ttcaagaatt ttgatttaca gaagaatata aacaaaacag ataccacgat
    12841 cgttgctcct gcaccaccaa ttgttaccgt ccattgataa aactgttcag gagcgatata
    12901 gggtaattgg gtggcagctg taccatctgc caatgccttt gcattctcat ccaacatgat
    12961 cagccacatt ggacgaacaa cagcccctac aatactcatg ccatggatac caaatgacca
    13021 caacaaatgg atcaaaaaca ttggtagtaa aacaccaagc aaattattcc ctaaaatatt
    13081 ggttaaaggc tcgaataacg ataataaggc agcgtttaca tcaaagcccg cgacgcttcg
    13141 aatcagccaa gtaattgtta aaatgactgc acctggaatc aatgcctcaa aactacgggc
    13201 aacagcaggt ggcacttgtt ctggcatttt gatagtaata tttcgatttt taaagaaacg
    13261 atatacttcc actgcaaaaa tcatagataa gatccccgca aacatcccag atgctcccaa
    13321 agaactcata ggtaagaccc agccaagagg tgcctcttca ggagttaaaa cgtttacagg
    13381 aacttgtaac ataaagaacg ttcctaaaga taatatacca cctgtcacac tatctaatcc
    13441 atatgattta gctagatccg aacccataac aaaagttgca taaatagcca tcaatcccat
    13501 cgtcatccta aagggtaaaa caatcgttgc cgaataaggg gcaataaatt cattccatcc
    13561 aggaaacggt aaattgataa agaccataaa aaatgtccca atcaaaatca atgacaatgt
    13621 tgaaacaacc ccattacgaa ttgctaataa atgacgctgt gtaccaattt ttgccattgg
    13681 tgggacaagt ttctcttcga cccatttcat cagcttttcc actaaaacca ctccttttca
    13741 ataaaatatg aaccattcat tgcatgacaa cgcaaagaat gttcataact aattatataa
    13801 ttaagaaatt ttatttcaat atattctctt aaataatcaa atttattttt aagaatcctg
    13861 aaaataagtt ttctaaatca taggagcaac aaaaaaattc gataattaac aaaaatcaaa
    13921 atgattaaat ctagtgattg aaacatatca tttcaaaaaa attttgtaaa ttcacccata
    13981 aatatcaccc tatttaactt ttttcatcgt acactaaaat tcaaaacaac tatctttaat
    14041 ctttacttct tggttttgtt ttaataaatt tccttcaaaa atgcctggag aaactacaat
    14101 gatcaccgta tctttttgtg cttgctccaa cttcttcaaa tctataatag ctaacagtgt
    14161 cccttctttt acctcctggt tactttcaac ccgtatctga aacggacttc cttcgagttc
    14221 aactgtatct aaacccatat ggatcagtat ttttctgcca gattcacttt cgatcgttat
    14281 ggcatgtcgg gtaggaaata tattatcgat tattccttta actggcgcat ggatatatcc
    14341 atcatgattc gttatagcgt atccaactcc tatcattttt gaagaaaaga cctcgtcttt
    14401 tactgctgtt aatggaataa tttgaccact agctacagct tttagaatgt ttcttgtttt
    14461 aaagaaatgc actttttatc acctctactt taatgctggc caatattttt tgtttacttt
    14521 gatcatttca tctagtattt tttttgcgac tctggcattt ggtacggttt gattcaatgt
    14581 aaatgcttgt aaagcttttt gataagaacc ttcaaagtaa gcatctacta gtaacttctc
    14641 tactgcaact tgtgcctcca tcaatccttt atgaaaatca ctgattggtt ttcttagtgt
    14701 aattggctcc acaccagttg caccaacata tgccggtatt tcaacaactg catctgaccg
    14761 tagattcgga atcgcccctt gattaggaac gattagcata aagcgacgac gatcatcatt
    14821 caacaaggaa atagctatat cgacgatata ttgtccatgc tccccaaaat taaagttcaa
    14881 tacttcttcc acaataccgc ggcgtatttt atcagccatt tctttggtat ttttctctcg
    14941 tccatccatg accatattag cacgtgtata ctctttgtca gtatgctcaa cgaccatatc
    15001 aggatataag taatactcta agtaattatt cgggatatta cttggaaaat ttttcgtgat
    15061 gactgacatc atttgaaagg ttttttgcca agttttatct cctatattaa aatcggcgac
    15121 ttgcatttct tttgttatta gtttttcaat aatctctggc ataatttctc gttgcaattc
    15181 tttatcataa atcgatgtat accagccaaa gtggtttaaa ccataatacg taacgatcca
    15241 attcttacga tcataaccgt aattcactgc aatcgtttct tcaattgaaa tagtcatatc
    15301 acaggcatta atcattttta cattcggata tttacgacga acagcttcag aaacgatcga
    15361 ctctggattt gtataattca aaatccatgc tttgggggca tagtcttgta tatgatcgac
    15421 aatttccaat aaacctttga ttgagcgcat cccataagca aatcctccga gtccacacgt
    15481 ttcttgtcct actaatccat gtttaagtgg aatcttttcg tccttttctc gcatctccaa
    15541 tcctccaaca cgaatttgtg agaaaacaaa atcgcatcct gtaaaagcaa gctttggatc
    15601 atccgttgca cgaatgcgaa tatttgaaaa accttttctt ttcagcataa atttaacaat
    15661 caagtacata tccatatttc tttcttcatc aatatcatat aaacgtattt cagataatgg
    15721 caaccgtttt tcattgttca aaatggcttg aacgattcct ggtgtatacg tactcccgcc
    15781 tccagctata gtgataatct gttttttcat catcatcttt tcctttctat tcttctaata
    15841 atttattgaa ttctgccata acataagtca cttctaagcc gatgataatt tgataatttt
    15901 tttcagttgg tttaatgatc ccgcttatcc ctaattgctt gattcgctgt tcctcgacca
    15961 tggtgggatc cactacctct acccgtaggc gtgtattaca actatagaca tccaggatat
    16021 tggcttttcc tccaaacgct tgtagcattt ttgttgccat atattcataa tttttacttg
    16081 ctaaccctaa ctctgtttct tctaaggtta cttcattgcc aaactctgcc ttagcttcac
    16141 gtcctaatgt ctgaatgttt ctcttattga tcaaataata aaaagtaacg taatacaagg
    16201 caaaaaagaa aattccgatt ggaagaatca aaatagcatt ggtagcgatt cgaaaattga
    16261 tgagataatc aacaatacat gctccgaatg taaaaccaat tcgtatattg aataagtaac
    16321 agacaatccc tgctaaaccg gcaaaaagtg catggatcac gtacaacata ggagaaagaa
    16381 acatgaaact aaattcaaca ggctcagtga tatttgcaat aaatgaagtt cctgcaccgc
    16441 ttcccatgat tcctttgacc atctctttat tttctttata agctgcttta tagatagcta
    16501 gacatatagc tggtatacca aacatcatta ctacaaaaaa aactgataaa aacagtccag
    16561 cctgaggatc tccgttgata aagcgtgtca tctctcctct gaaaacttcc ttgctaggag
    16621 atgtatagct tcctaaatcg taataaatat acgtattcaa cacatggtgc agtccaaagg
    16681 ggatcagcaa acgattcaaa aacataaata tccccacacc taatgctccc atatcaacga
    16741 gcagttttgc aaaattatca atcccaattt ggatgagcgg ccagataaag cccaaaaaaa
    16801 cagctgcgat tgtttgtaga atcatcacca tagtcaatgg gaatttttcg cccgcaaaat
    16861 aagaaaaaac tactggtaat ttttgttctt taaagcgatt atacgtccat gccgctacta
    16921 aaccggaaat aattccacca aaaatcccca tattcacttc tgggtccata atttctaagc
    16981 cttttttcaa ggtagcaatc gctaaaaaac cagtaagtgc aggtattcct ttgtccttat
    17041 ttttgacaaa accgattgca actcctatag caaataagat atccaagttt ccaaaaacgg
    17101 catttccagc tgcaccaatt actgggatgt tcagcatatc gtcagctgat aaacgcatga
    17161 tcaatcccgc taatggcatc gctgcaactg gaagtagcat cgctcttcca agcttctgca
    17221 catttgattt aacattcatt tttattcctc ctctattaaa tatcctcata tgttactaac
    17281 tcaatcaaag gatcattttt cactttttga gcaaatgctg aatgaattaa aaattcgact
    17341 tggtgggtac gaggatacac aaaacttgaa ccatttaaca attcctgatc caaatacgct
    17401 gcgtgacaca tgacttcgat cgttttatct tctctcaata tcatgagtaa acttgccaaa
    17461 tattcttcca cactcgtatt gatttgtcgt tttttttcat cagtttctcc tacgacatcg
    17521 aaacaaggct caaaataatc gacatgacga acttcatctt ttcgttcaaa gttgctccga
    17581 accggcaaat catatttttt tgctaatgta acaactacct cctgattttc atccaaagta
    17641 tgagtatgat gatgactgtc taaatgagtt ggtatgatcc ccgcatgata aattttttga
    17701 atctgagcat tccattcctg atacagttga tctttgtcaa tgttaaatgg atgctgataa
    17761 taagataagg atctgaactc tccgctttcg ataagagtat cgacagtttt gaggagtggt
    17821 ttgccacacg tcaatgttaa atggactcct acacctagcc taggcatttc ctttcttagt
    17881 ttcacagcat gctcgaaacc cggcatattt gccatcaatg tagttgatgt caaaattcct
    17941 cgctgataag catccataat cccataattc acaccatggc tatagccaaa atcatccgaa
    18001 ttaaaaatca cttttcccat ttcattctcc ttcttttttc tactaaaata ggcgcaacca
    18061 aataatcata gtccatttac tatgtgtcat ttggttgcgc ctatagatag ttacgccctt
    18121 attttaatag attcttgcta gatgaattgc caaatagatg atttcatttt cttgaatggc
    18181 aagttgaaat tgctgttcga tgatatcttt aatctttagt gctgtacaat acgctttgct
    18241 atgtttaaat gtttcagtaa aaaaaccaat attttctact ggcgtttctt cctgataaat
    18301 caagcgttta accaggaatt tgatatgaac cattaagcga tgataagtca gtgattcttt
    18361 atcataaacg tttgaatagg atttttctag atgggacaaa atcgtggtcg tcatttctac
    18421 tatttttaag ctctttaaac tattaggctc tcctagctca gcattaatga tatgcatagt
    18481 gatgaatcct acttcatttg accctaactc ggtttgatat cgatgattga ttcgctcgac
    18541 cacttctact gctatatcat attcatttgg ataaaggaat ctcatttctg gcaacataat
    18601 tgctgtgaca tctctatctt ctctttttcg ttgaatagca aaataaatat gatctgtcaa
    18661 tgtaatatag atatttgaat ctaatggaga ggagatccta gctgttatca gttcaatcac
    18721 ttcttccgca aaatccataa attcgattgg aatctgcgag actatctcac tgaatcgttt
    18781 gatcttttct ttagaatcta atacaaataa tttgtcagca tcctcaacat caaatggctt
    18841 actcacttta gcagaaaagc caatcccttt ccccatcgca attttttcta ttccatcgtc
    18901 atcgatcaat acagcattat gattcagctt tttcatcaca tacaccgtta attcacctcc
    18961 tctatatgat aaaacaaaac aacttgcaga ctccttcata catatttttg tctccaaaca
    19021 atttttaaag acaaaaaacg acctaagaaa gaaccctttc ttaggtcgtg cctaattgaa
    19081 tagtagcacc ctacataatt tacaaaaata gtttaacaca taataaaagc gttatcaata
    19141 tcttttttac tcgttttatg ataatacttg tatcgaattg atttggaggt aattacataa
    19201 aaacaaaaaa aatatagcaa ctctctataa gaaagttgct atattgataa ttataccggc
    19261 ggccggggtc gaaccggcac gtcctcaacg gacactggat tttgagtcca gcgcgtctgc
    19321 caattccgcc acgccggcaa atttaaaaat aataactggg gtagctggat tcgaaccaac
    19381 gcatgaggga gtcaaagtcc cttgccttac cgcttggcta taccccaaga ataaagggcg
    19441 aatgatggga atcgaaccca cgaatgccgg agccacaatc cggtgcgtta accacttcgc
    19501 cacattcgcc atcataaaag atgttattta atttctcaat aaaaaactaa gatgaagaca
    19561 tcttagtcaa taccggcggc cggggtcgaa ccggcacgcc ctcaacgggc actggatttt
    19621 gagtccagcg cgtctgccaa ttccgccacg ccggcaagtt gatttattag tactaaggcg
    19681 gtaaccggat ttgaaccggt gatgaaggtt ttgcagacct ctgccttacc acttggctat
    19741 accgccatta tactattatc aatctataaa ataaagaata aattatag
//
LOCUS       DAIGSZ010000056        19530 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.056, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000056 DAIGSZ010000000
VERSION     DAIGSZ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.056"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(111..275)
                     /locus_tag="NOB31_002087"
     CDS             complement(111..275)
                     /locus_tag="NOB31_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974281.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            570..1898
                     /locus_tag="NOB31_002088"
     CDS             570..1898
                     /locus_tag="NOB31_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HCI0974282.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2100..2933
                     /locus_tag="NOB31_002089"
     CDS             2100..2933
                     /locus_tag="NOB31_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HCI0974283.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2949..3686
                     /locus_tag="NOB31_002090"
     CDS             2949..3686
                     /locus_tag="NOB31_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HCI0974284.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3841..4767)
                     /locus_tag="NOB31_002091"
     CDS             complement(3841..4767)
                     /locus_tag="NOB31_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HCI0974285.1"
                     /translation="MKENMLTGGVSPDVANPLLDAEITIPKHVELLVEDIFNLPSPHI
                     MPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIGNKLPIVLTGAMRSS
                     NELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTKTHTTNVATFRTPTL
                     GPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGDLLEAIAHTKVDGLV
                     IEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDYEGGGKELEKMGIIF
                     CNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5042..5875
                     /locus_tag="NOB31_002092"
     CDS             5042..5875
                     /locus_tag="NOB31_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HCI0974286.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5909..6748
                     /locus_tag="NOB31_002093"
     CDS             5909..6748
                     /locus_tag="NOB31_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0974287.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6774..7334
                     /locus_tag="NOB31_002094"
     CDS             6774..7334
                     /locus_tag="NOB31_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCI0974288.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7533..9254
                     /locus_tag="NOB31_002095"
     CDS             7533..9254
                     /locus_tag="NOB31_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HCI0974289.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9419..10561
                     /locus_tag="NOB31_002096"
     CDS             9419..10561
                     /locus_tag="NOB31_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCI0974290.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10577..11788
                     /gene="thiI"
                     /locus_tag="NOB31_002097"
     CDS             10577..11788
                     /gene="thiI"
                     /locus_tag="NOB31_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HCI0974291.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12361..13008
                     /locus_tag="NOB31_002098"
     CDS             12361..13008
                     /locus_tag="NOB31_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCI0974292.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    13137..13353
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13401..16046
                     /locus_tag="NOB31_002099"
     CDS             13401..16046
                     /locus_tag="NOB31_002099"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HCI0974293.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16356..17669
                     /locus_tag="NOB31_002100"
     CDS             16356..17669
                     /locus_tag="NOB31_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HCI0974294.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17659..18312
                     /locus_tag="NOB31_002101"
     CDS             17659..18312
                     /locus_tag="NOB31_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0974295.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18367..19059
                     /gene="radC"
                     /locus_tag="NOB31_002102"
     CDS             18367..19059
                     /gene="radC"
                     /locus_tag="NOB31_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCI0974296.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            19209..19409
                     /locus_tag="NOB31_002103"
     CDS             19209..19409
                     /locus_tag="NOB31_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0974297.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         6574 a         3293 c         4137 g         5526 t
ORIGIN      
        1 aatccaatca cttgggtttc tttttctttt attattatga tgaatcaagc tttctgtttt
       61 tgtcacgtat gttgtaatct ttacgaaaga gtagagttgg ctactcataa tcaaccatac
      121 ttcccatcat cgctaaatac gaaataaatc agcattccta caccaatcaa agcacaagct
      181 gcaccaagaa aagggatgac attcccaaag ttatctgtat tcataagtat gccaccaccc
      241 acaaacaaaa agccgccagc aatcaggttt ttcattttat tcatctcctt tcttacgtta
      301 tagtatttcc ttctttcaat gagtattttg aaagctatct tattgtatga tgttcttcta
      361 ggcctcttct ttattataca ggccattttc gttatctcat agaaatattc ctttttatct
      421 gaaaactatt gtataccgta tgacattttt cttcatgaag ttgtaagtat attctcattc
      481 aaatgaaaat ttcatcatag aagagattgt atttctaaat tcttaagagt aaaatacgaa
      541 gtataacttg gatttggaag gatgattgga tgaaagctat tacgcctgat atgacaacaa
      601 aatttaacaa acagtttcaa gcaaatatca aacagcaggc attgcagcgg gcagttgtga
      661 agaacggaat tactgcttct gctgaaaatg tttcagcaca tgtggagaat acaccggtat
      721 tttctataga tttggctacg gggaaagtgg ctaatcaaat gcaatcgggg cgttgctgga
      781 tgtttgctgc actgaacaca ttccgtcata agatgctgaa tcaattccat ttaaaagagt
      841 ttgaattatc acaaaattac acttttttct gggataaata tgaaaaggca aattatttct
      901 atgaaaacat cattgcaaca ggaaaagagg caatcgatag ccggaaagta gctttcttac
      961 tcgctactcc tcaacaagat ggcggccaat gggatatgat cgtttcatta ttccaaaaat
     1021 atggcgttgt gcctaaatcg gtgatgccgg aaagtgcgaa tagttcaaat tctcgagatt
     1081 tgaataacta cttgaacaaa ttactgcgta aagatgcagt agtgttacgg aaaatggttg
     1141 ctcaaggaga aacattagac gctattgaag aaaagaaaga agaaatgcta gaaagcattt
     1201 ataacttctt agctatctca ttaggaacac ctccaaaaga attcgatttt gagtaccgcg
     1261 atgaagaaaa gaactatcat cttgaccgag gactgacacc acaaattttt tatgataaat
     1321 acatcggtgt aaaattagat gattatgtta gcgtgatcaa tgcaccaaca aaagacaaac
     1381 cattcaatcg ttcttataca gtagagatgc taggaaatgt cgttggcggg aaagaagtca
     1441 aatatctgaa tgttgatatg gaaactttca aaaaattagc gattgctcag cttgaagaag
     1501 gagaatctgt ttggtttggt tgtgatgtag gtcaatcttc tactagaact agtggcatca
     1561 tggccttaga tgcttattca atggatgatc tatttgatac ggattttaca atgactaaag
     1621 ctgaacgttt agattttgga gaaagtctga tgacccatgc gatggtattg accggtgttg
     1681 acttagtaga cgggcaatca acaaaatgga aagtcgaaaa tagctggggc gaaaaagttg
     1741 gaaagaatgg cttctttgtt atgagtgatg cctggatgga cgaatatacg taccaaatcg
     1801 ttgtaagaaa agatttattg acgaaagagc aattaaatgc gttcaatgaa gaaccaattg
     1861 ttctatctcc gtgggatcca atgggtgctt tagcatagac gagtatttca atgaagagta
     1921 tgtagtaaag ataaaaagag ctggcttaag ccagctcttt ttatctttaa agtccattcc
     1981 ctgtttttta tggtccctgt gctataattc taaataaagg ataaggattg gaaataatcc
     2041 ttttatcatt aaaaatatga tgacgaagta gaataaaatt gggagtaggg gggaaagtca
     2101 tggatatcca aactgtttta tctgatctga aattaaatgg taaagtgatt ccagttgttg
     2161 gtggcgatgt taatcagacc tatcgtataa aaaccgaaca tcgtgcttat tttttaaaaa
     2221 tccatccgaa tgtaaaaaaa ggattttttg aagcagaagt agacggatta aaagaactgt
     2281 cagcattcgt acgtgtaccg gatacgtata tgctaggtga aacaagtgaa ggcgcttatt
     2341 tgttaatgga atggatcgag ccgggaaaag gggatcaacg agatcttgct gcagctttag
     2401 ctaatctcca tcagcaaaca gcgccacaat ttggttttcg taaagataac tatttgggta
     2461 cacttgttca gaaaaattct tttgaagaag attggtggac ttttttcttt aaagatcggc
     2521 ttgaatccca gatttctttg gcagaagaaa cgaatcgatg gaatgtacag cgtcaagaaa
     2581 agtatctgcg atttaaagaa cgtgtattga aatcggttga accaaaaaag atcactccac
     2641 gcctcttgca cggagacctg tggagtggta atgtgttctt tgaccagcaa gggcatccag
     2701 tttttgtcga cccagctgtt tcttatggga atcgggaaca agatattgca atgagccagt
     2761 tattcggtgg tttccgaccg gaatttttag atgcttatca aactatattt ccattagaaa
     2821 agggatggaa agaccgactg ccgatttacc agttatatta tcttttggca catttgaata
     2881 tgtttggaga aagttacggt tcccaagtag atcaattact agaaaatttt taagaggagg
     2941 gcgtgttttt ggcaaaaaaa tataccaaaa agcatgaagt ttcatattat gagtgtgaca
     3001 tcaaccaaac gatgacattt ccttcgatgt taggagtagt tatcaaaacg tctgaagatc
     3061 aaagcgacca gttgggaaga ggcagtgaat tcgtcaatag ctttggactt acttgggtca
     3121 tcacgaatta ttccatggag attaatcgtc tccctagagt cggtgaagta atctcagtaa
     3181 cgactcaagc catggagtac aataagtttt tctgttatcg gaacttctgg atccatgatg
     3241 aagatgggaa agaattagtc aaaatagaat ctgttttcgt attgatggat tttgtgaatc
     3301 gaaaaatgag cagtgttaat gaagagatca ttgctccttt tgagagtgag aagatcaaga
     3361 aaatcaagcg tcaggaaaaa attgaaaaga ttgattcggg cttcatgttg ccatatcgtg
     3421 ttcgttttta tgatatcgat agtaatcagc atgttaataa tgcgatgtat tttaattgga
     3481 tcattgacgt attaggatat gactttttga ctacgcatgt tccagaaaaa gtaattattc
     3541 gatttgataa agaagtagag tacgggaatg agatcgaaag ccattttgaa caaatcccta
     3601 tcgaaaatgg tgtcaaaaca aaacatgaaa tccgaatgca agaacagctg tattgtgaag
     3661 caaatattat atggaaaaat aaataaaaaa gaggttgtga cagaaggggg caacttcaag
     3721 aaataagaag aaatttacga aaattgtttc tcaaattttt gtaaattttc gacttagttt
     3781 tcgaagaagc tatttttgtc acagcctctc tttttaagtt tagctattag ataatgatgt
     3841 ttagttttgg ataaacgaaa tcaattcttc acccgacaaa ccatagttta cagcaatcaa
     3901 tagttttaaa cgtgcttttt gactattaat actgttacag aaaataatcc ccattttttc
     3961 tagttctttt cccccgcctt cataatcata aacaggctct gcgattccat tgaaacaacg
     4021 agaaacaagt actacaggga ttttttggac aagaagcttt tccaaagcag ctaaggcttg
     4081 tggagggaga ttccccgcac ctaaagcttc gattaccaaa ccgtctactt tcgtatgggc
     4141 gatggcttcc aataagtccc cttgcatccc agcatatgct ttaacgatcg ggatagtccc
     4201 atctacagcg gaaatgtcca gtcgctttgt ttctaaaagt tcctgcaaga ataaaattcg
     4261 attcttagtt actaagccga tgggacccaa tgtaggtgtt cggaaagtag caacatttgt
     4321 ggtatgggtc tttgtcacgt agcgtgcaga atggatctca tcgttcatga ccaccaaaac
     4381 ccccttatct agcgcttctt cacaacttgc gacacgaatc gcactttcaa aattataaag
     4441 gccgtcactt ccaagttcat tacttgaacg cattgcccca gtcaaaacaa ttggtaattt
     4501 gttgccaatc gttgtatcaa gaaaaaaagc agtttcttct aatgtatctg taccgtgtgt
     4561 gatcaccact ccggatatac ctgatgcata agcggacaag atacgttctt ttaataccaa
     4621 catgtgagaa ggcatgatgt gtggtgaggg aagattgaag atatcttcaa ctaataattc
     4681 tacatgcttg gggattgtga tttctgcatc taataatggg tttgccacat caggactaac
     4741 accgcccgtg agcatgtttt ctttcatggc gatcgttccg ccggtgtgta gtacaagtat
     4801 tttttttcat tttacagact tccttacgaa taattttgca tagccgttaa atcttattgt
     4861 atactatata aaagagtttt gctatcagtg aagaataacg aatagcctaa cttatcataa
     4921 aaaagctgac cttattaaaa tggaaaagac tcaaccttga cctcctaata caatggagta
     4981 tctggttgag tttcttttac aagaaagcag ccaaggaaat caatcacgaa ggtggccgga
     5041 aatgatcaga atcggattaa catcgtttaa agaacatgac aaattaactg gtaaaaagaa
     5101 taacactctt tatgaatatg cagggtttct acccttagtg gaattagata ctgcctatta
     5161 tggaattccc cgaaagtcct cagttgagaa ttggataagt gaagtacctg aatcatttcg
     5221 ctttgtagtc aaagtctatc aaggaatcag cggtcaagga gactggaagc cttattatca
     5281 gaccgaagaa gagatgattg cgcatttttt agatgttatg tcgccaatgg tagatgctgg
     5341 aaagatgttt tgctttttag tccaattccc ctcatcattc aaatgtacga aagaaaatgt
     5401 ccagtacttg cgcaaactta gaaagtggtt tgagggttat cctgtttcta tagaattgcg
     5461 ggattattct tggtacagcg atgaatttct tgaacgtaca agaaacttta tgtctagagc
     5521 cgctttttct ttagccatca tcgatgagcc acagttgctg aatacaacga ttccttttga
     5581 tccatttgtc accaatccga actttgctct ttttcgattc catggtagga atgcgcaagg
     5641 atggcaagca aatgataaag agtggcgtaa aaaaagaacg ttatatcgtt attcagaaaa
     5701 agaactgcaa gaactagcac atgaagtcaa agtagttgat tctaagacaa aagaggtagg
     5761 tgtgattttt aataataatt ctggtggtga tgcggctgaa aatgcattag cactgcaaaa
     5821 aatattaaat atcaagccag atggactcaa tccaacccaa atggatctgt tttaagggct
     5881 tattttattc aagaaagggg cgaagtctat gatcaaagct attttttttg atattgacgg
     5941 aacattggtc accaatcgtt caaaagcgtt ggaatcaaca aaacaagcaa ttgaatatgc
     6001 tcggaaaaac ggcattttat gcggtgtagc aacggggcgc agcccagtaa agatcaaaga
     6061 aatcattgat gaattggaat tagatatgta tgtcgtgtat aatggtcaac tggtttttac
     6121 tgcagatcgc acgattatcg accacccttt tgaacaaaaa gtattggaac atattgttga
     6181 atttgcagat gagaaccatc gacaaatcgt ttttggtgcg agaaatcggt tagatggatc
     6241 aacgacgatg ctattaggac aatcgatttt tatcaagcga ctagtcagct ttttaccgcg
     6301 taaattcccg gtacgtctga tgaaaaaaat cctccaggtt tttagccctc accgacaaaa
     6361 ggatcgttat gaaacgttag agatattaaa agaaccaatt tatcaatgta tattgctcag
     6421 tccggagtca gaacagaaaa agttagaaca tcgctttccc gagtgtacgt ttcagcgttc
     6481 aaatacgtat actgtagata tcatcccaaa aggtggttca aaattactag gcatccaagc
     6541 tttcgcaaat gctgtcgaaa ttgaaatgga agaaattatg gcattcggcg atcattacaa
     6601 tgatatcgag atgctgaaag gtgtaggaat tggagtggcc atggggaatg ctcagatcga
     6661 agtaaaacat gctgcagact ttgtgactca atcaaatgaa gaagatggga tatacgaagg
     6721 actgaaacac ttcggtctga tttattagtc aatgaaagaa ggaaaaaatc agtatggaag
     6781 cagagacacc ttttcaaaaa gtagaaacat tccacaaaac ttttgatcca agaagaccag
     6841 agatacccac ggcttttaca gaaaatgaag ctcatacacg tgctgcgttc aaaatagaag
     6901 aacttgttga atttgttgca gctacttcac ctaataaaga acaactgcat gaagctgtta
     6961 tgctgctgca cgaagcatta gataaagcag aagaaaaaat acttggtaaa acacagtggg
     7021 gaagtgatcc gctggttgaa caagtagatg cactgacaga tatcctttac tttacttatg
     7081 gttctttttc attactagga atagtgcctg atcgaatatt cgaaatcgtc catcaggcaa
     7141 atatggggaa attatttcca gatggaaaac ctcattatga ccctgtaaca aataaagtgt
     7201 tgaaacctga aaactggcag atggaatatg ctccagaacc taaaatcgcg gcagaaatcc
     7261 aacgtcagat tcaagaagcg attgctaaga agaaatccgc tgatataggc atgtgcacaa
     7321 atgaaaaaga gtgatcagag tttcactatt tttgttatct ttatacgatg gaaaaacaaa
     7381 agattttcgt ttaagttagt gaatgcatga aaatagtatg ctataatcta gaatagatgt
     7441 cttttgcacg agagacgtat tatttggatt tatgccaagc agaacgccat ctgttgcata
     7501 aaagatgcat actgaaaacg gaggaaccat aaatgggaaa taatgttatc atcggaatcg
     7561 tcattgcaat cattatagtc gccattgtcg tctttttggt tagttacttg atgaagaaaa
     7621 aaaaccaaga tcgattggat gccttagaaa aacgcaagga agaattattt gacttgccag
     7681 tgattgaaga agtcgatgat gttaaaaaaa tgcatctggt tgggcaaagc caaaatacct
     7741 ttcgtgaatg gagtcaaaaa tggaatgaca tatctacttc ctcgttcgct gaactagaaa
     7801 gtcaaatttt cgaagtggaa aacctcaatg aaagttttcg gttcttaaaa ggaaaaaaag
     7861 cagttgttga agcagaagct acaatggacc aaatggagaa acaagtgacg gaaatccgtg
     7921 aaggtctaaa ggaattgcgg gaaacggaag aacgcaactc actagctgtt cagcaggcac
     7981 ttgacgtcta tgaagaactg aaagaaaaag tcagagaaga cgagcatgaa tacggaccag
     8041 ctctttttga attgcaaaaa cagatcaaag tgatcgaaaa agaatttacg cagtttgtga
     8101 ctttaaacac ttctggagac cctgttgaag cccgcgaggt tttggataaa gcagaaaaac
     8161 atacgtatga agtggaagct ctgatgaaaa aaattccacc gctgtatgag gagctccata
     8221 ccactttccc tgaacaactt gaagaaatca gtgatactta cgagaaattg atggaagaac
     8281 aatatgtatt cccagaagaa gatcttgctg aagatatcgc aaaagtaagt cgaagaattg
     8341 aaaattcatt agccaatctt gaaaaaacag aagttgaaac ggtcgaattt gaaaaccgtg
     8401 aaacagctga tttgattgat tcgttatatg atatcttaga acgggaaatg gaagctcaga
     8461 gatatgtaaa aactaaccaa tcaacgattg cagagtatat caaacataca acaaagaata
     8521 accgtcaatt attgattgag ctggatcaca catctcaaag ctatacattg aaccacaatg
     8581 aaattggccg tgtacgaggt ttccaaaccg aagtggaaga aatggaacgt caaaatgaac
     8641 agatgattcc acagatccgt caacacgaaa ttccttattc agaagtgcgc acgttctata
     8701 aaacagtctt caaagtctta gaagatatcg aaaagcaaca agtagagatc gacgactcat
     8761 tacatgaatt gagaaaaggc gaaaaagaag cgcaagaaaa gatcgataca ttcgaattca
     8821 aattgcgcag tttgaaacgt tttgtagaaa aacaacgttt gcctggcttg ccgaatgatt
     8881 acctagaatt cttttttgtt gctactgacc gtattgaaga actaagtgtt gtcttgaata
     8941 aaattcgagt aaacatggaa gaggtcaatc gtttagttgc tctatgtgaa gaagatctag
     9001 aattattaga taagaagaca catgatttag tagatgcagc agcattaacg gagcaaatgc
     9061 tccaatatgc aaatcgttat cgtcatacac acgaagaagt gagagaagca attgataaaa
     9121 gctactattt attcaataaa gaatatcact atcaagaagc attagacgaa atcggtacag
     9181 cattagagcg agtagaacct ggtgctttca aacgcatcga agatttttat tttaatcatc
     9241 cagacttagt ataaagcaaa aaagttagta aaccagcaag agcaagacgg attattgtct
     9301 tgttcttgtc tttttttgta tatttgaaaa ttgaaacaag tgaaaatttc acctgctctt
     9361 gaaagcacct tggacaaccg ttataataga aaagaatttc aaaaaagagg ggtttcttat
     9421 gatatatttt gataacagtg caacaacccc aatctttccg caaagcttag atgcatatgt
     9481 aaaaaccagt cagcggatta ttgggaatcc atcaagcttg catgatttag gcaatcaagc
     9541 taaccggttg ttgcagcaag caagaaagca gatcgctgat ttgatccatg tagaaccaga
     9601 agaaatctat tttacttcag gcggaacaga aggagataac tgggtattaa aaggaacgat
     9661 gatcgaaaaa agagaatatg ggaatcatat gatcatttca ggagtcgaac atccggccgt
     9721 cagcgagaca gcagaacaat taaaagaatt aggaatcgaa gtaagtatcg ccccagtgga
     9781 taaacgcgga tttgtacgtg tcgacgaatt gaaagaatta ataagaaaag agacagtatt
     9841 agtctctgtt atggctgtga ataatgaagt aggatcgatt cagcccatcc aggaaatcag
     9901 tgatcttttg gatgattttc ctaaaattca tttccatgta gatgctgttc aggcgattgg
     9961 aaaagtacca ttctcgcaat ggttgacaga aagagttgat tttgcaacat tttcagctca
    10021 taaattccat ggcccacggg gaactggttt catttattgg aaaaagggtc gtcgtttagc
    10081 accattactg acaggtggag ggcaagaaag aaatcagcga agtgggacag aaaatgttcc
    10141 aggtattgtg gctatggtta aagctttacg tttatcatta gagataaagg aacaaaaacc
    10201 tgagcagaca caacgcttaa aagtagctct aatcaatgcg ttgaagacgt atgagaaagt
    10261 gacgattttt tcagaaggaa ctgactatgc accgcatatt ttatgttttg ctctaaaagg
    10321 aattcgcggc gaagttctcg tccatgcctt agaagaaaaa caaatatttg tttctactac
    10381 tagtgcctgc tcctcacgta aacatatggc aagcagtaca ttgcacgcaa tgcatgtacc
    10441 aaatgatctg gctacatctg ctgttcgaat cagcttagat gaaaacaatt cgcttgcaga
    10501 agtcgagcaa tttatgatta ttttcaagca gctttataag aaattttctg caatcaatta
    10561 aaagaggagt gttcttgtga aatacagtga aattatggtc cgttatgggg aactttcgac
    10621 aaaaggaaag aatcgaaaaa gctttatcat gcaactagca caaaatgtca gacaagcttt
    10681 gaaagacttt ccagaaatca aaatccatgc tgatcgggac cggatgcatc ttttattgaa
    10741 tggcgcagac gggcagctag ttattccaaa actagcaaaa atatttggga tccaaaattt
    10801 ctctccaagt attcgtgtag aaaaagatgt cgaagttttg aaacaagctg ttcaagacat
    10861 catgaaagaa atttatactg ggaaagaaac atttaaaatt atcgctaaaa gaagcgatca
    10921 ccaatttgaa ttgacaagta atgaattgaa tcaaacatta ggtaatgctg tttttgatat
    10981 tttcccgcat atccaagttc aaatgcgtca accagatatt ccattacgtg tagagattcg
    11041 gcgtgatggc gcttatctat cgtatgaaac gatcaaggga gctggaggat tgcccgtagg
    11101 aacaagcgga aaaggaatgc ttatgctttc tggggggatt gattctcctg tagcagggta
    11161 ctttgccatg aagcggggag tggaaattga agctgttcat tttgctagtc cgccgtatac
    11221 aagtgaacaa gcactgcaaa aagcaaaaga tctaacagcc aaactagcac cttatgtggg
    11281 aacgatccat tttatcgaag tgccatttac cgagattcaa gaagaaatca aaaagtcagt
    11341 gccacaagga tattggatga caattactcg tcgaatgatg ttgcgtttga ccgatgaaat
    11401 tcgccgtatt cgtcatggtt tagtcatttt gaatggtgaa tcattaggtc aagtggcttc
    11461 acaaactttg caaagtatgg tggctatcaa tgaagtaacg aatacgccaa tcattcggcc
    11521 tgtagcgaca atggataaac ttgaaatcat tgaagtagca gaacagatcg atacatttaa
    11581 tctttctatc cagccttttg aagattgctg tacgattttt gctcctccac agccaaaaac
    11641 acgccctcaa ctggaaaagg tccatcaata tgaagagcgt ttagcaatag atgaaatgat
    11701 ccaacgagca ctagctggct tgaagatgga agagatacaa gcagaatcgt ctaatgaaaa
    11761 aactgaagaa ttttcagaat tgctataaga ggttatgaaa atagtgtttt gaccagagta
    11821 ttagagaaac aaaacgaaaa aatagctcca tgtattttac cgtttttgaa ctaatgtcga
    11881 agattagctg attgaatacc atttatcaag aagttatgga aaagccggtt cttttttact
    11941 aactgaaaaa taaaatttta tttagagatc aagctacagt tgataaatga tataaaaaag
    12001 agaatttccc atgaaatagc gaggttgtga cagaagtggg cagcttcaag aaataagaag
    12061 gaatttacga aaattgcttt tcaaattttt gtgaaatttc ggcttatttt tcgaagaagt
    12121 tacttctgga acaccgtgta tcagaggttg cgaaaaagct gccctgcatc aagtaataag
    12181 aacagccaaa caaaaatagt tcctcatatt ttacgtttgg ttgagcttat taccgcagat
    12241 gcaagctttt gaacaccgtt ttatttgtct cacacccttt tccttcctac ttgtaacctt
    12301 gctcccgtgt tagaaacatg ttacactaaa tatgtgaaat tattaacaag gagcgtcgtt
    12361 atgcgagaaa aaacagatac actgccaaaa gcaactgcga aaagattacc tttatattta
    12421 cgctacttga agatgctgga tgactcaggt ataagtagaa tcaaatcaaa tgagttcagc
    12481 gaaatcaccc aaattccttc tgcaacgatc cgcagagact tctcgcaatt aggcgagcta
    12541 ggcagaagcg gatatggcta tgatgtccct tttcttatcg atgtattcaa taatatcctt
    12601 aatactaaag aagaaaaacg aatcgcatta gtaggatatg gaaatcttgg caaagcattg
    12661 aaacacaaca attttagaag aaatgaaaat ctaaatatcg tgtgcgtctt tgataatgat
    12721 ccagcactga tcaatcgagt aattgatgga gaaatgatct atccgattga tcgtttcgcg
    12781 gagatagcca aagcaaaaaa tgtgacagta gcaatctcta cggtaccaag taaatattca
    12841 caatctgcta ttgatgaaat tgtcaaagga aatgtaaccg ctatacttaa ttttgcgcct
    12901 gacagagtaa ctgtcccagc ttatgtcaat gttcaataca ttgatttgac aaccgagttg
    12961 cagacgctta tttactttga tgagaattac tcagaagttt tttcttagga aaatttgagt
    13021 aggcttattg atcttgcgag aactcgtcgt aattctttca aaaatttttt agtactaaat
    13081 gaagtggttt tttcacgacc acttgttgac taaaaaaaaa aaccattgta gaatgaagca
    13141 taacgctgaa caagaggagt aactggcaca ttcattctta gagagagaac tatctgctga
    13201 aaggttctca atgacaacca gtgaaggtag cttgggagtt tctgtcttga atggagtaga
    13261 gatagacgag tcgtgatcgt taactcactt gagaggcaat aatgattgat tattgcaatt
    13321 taggtggtac cgcgtaaatc atacgtccta gaatacgaaa gtattttagg acgtttttta
    13381 gtttaaagga ggaaaacagc atgacggaag aaaataacct atcaacaaaa tataatccgc
    13441 aagaagttga agctggacgt tatcagcatt ggttagaaca agatttgttt aaaccgagcg
    13501 gagataaaaa agcaaaacct tattcaatcg taatcccgcc cccaaatgtt actggaaaac
    13561 ttcatttagg gcatgcttgg gatacgacct tgcaagatat gctgattcgt caaaagagaa
    13621 tgcaaggata tgatacttta tggctgcctg gtatggacca tgcaggaatc gcgacacaag
    13681 caaaagtaga agcgaagctt agagagcaag ggatttctcg ttatgatcta ggtcgtgaaa
    13741 agttcatcga tcaagtgtgg gaatggaaag aagagtatgc gagccacatc cgcgaacagt
    13801 gggctaaaat gggcttatct ttagattaca gtagggaacg ttttacatta gatgatggat
    13861 tatctgaagc agtacgtaaa gtttttgtta ccttatacga aaaaggtttg atttatcgtg
    13921 gtgaatatat catcaactgg gatcctcaag cacgaacagc tctatctgat atcgaagtta
    13981 ttcataaaga tatcgaaggc gccttttatc atatgagcta tgaactagca gatggatcag
    14041 gcgtagtaga aattgcgaca acccgtccag aaacgatgtt gggagatacg gcgattgctg
    14101 ttcatccaga agacgagcgt tatcaagcgc tcatcggcaa aaaagtgatt ctacctttag
    14161 tcaataaaca aatcccaatc attgcagatg aatatgtaga tatggaattc gggacaggtg
    14221 tagtaaaaat cactccagca catgatccaa acgactttga ggtaggtaat cgtcatgatc
    14281 ttccacgcgt aaatgttatg gatgatgatg gtacgatgaa tgaactagca ggaaaatatg
    14341 ctggaatgga acgttttgct gctcgtaaag caatcgtgca agatctgaaa gaaatcggtc
    14401 gattgattaa aatcgatacg atgatccaca gtgtgggtca ttccgagcgg acaggtgtcg
    14461 ttgttgaacc tcggctgtct actcaatggt ttgtaaaaat ggcgccgtta gcgaaaaaag
    14521 ccattgataa ccaagaaaca gatcaagcag tggaattctt ccctccaaga ttcaatcaaa
    14581 cgtttttacg ttggatggaa aatgtccatg attgggtaat ctcacgacaa ttatggtggg
    14641 gacatcaaat tcctgcatgg tatcacaaag aaacaggtga aatgtatgta gggatggaag
    14701 caccagcgga tagtgaaaac tgggtacaag atcctgatgt tttagacact tggtttagtt
    14761 cagctttgtg gcctttctca acaatgggct ggccagatac ggaaagcgaa gattataagc
    14821 gatacttccc tactagcact ttagtaaccg gttatgacat cattttcttc tgggtaagca
    14881 gaatgatttt ccaaagcttg gaatttactg gcgaacgtcc atttgagaat gtcttgattc
    14941 atggattgat tcgtgacgaa caagggcgga agatgagtaa atcattaggt aatggaatcg
    15001 atccgatgga agtaatcgaa aagtatggag cagatgctct ccgctggttc ttatcgaatg
    15061 gttctgcacc aggacaagat gtccgcttca gctatgaaaa aatggatgct tcttggaact
    15121 ttatcaacaa aatctggaat gcttcacgtt tcgttatcat gaatatcgaa ggaatgaccg
    15181 tagaagagat cgatttatct ggagaaaaat cagtggctga ccggtggatc cttactcgtt
    15241 tgaatgaaac gatcgaacga gtaactgagc tatttgatcg ttttgaattt ggtgaagcag
    15301 gtcgacaact gtataacttt atctgggatg atttttgtga ctggtacatc gaaatgagta
    15361 aagaagtact ttatggagat gatgctgttt caaaacaaac cacccgtagc atcttagtcc
    15421 atacacttga tcagatccta cgtttattgc atccaatcat gccattcgtt acagaagaaa
    15481 tatgggaaca tattcctcat cagggaaatt ctctagtagt ggcagaatat cctgttgtac
    15541 gtccagagtt tgatgatgaa acagcttcta aagggatgga agtattgaaa gaattgattc
    15601 gagccgttcg aaatattcgt tcagaagtga atacaccatt gtctaaacca attacgttgc
    15661 taattaaaac aaacgatgct aaaatcgatc aatttttagt tgaaaataca agctatatcg
    15721 aacgcttctg taatcccgaa gagttgacga tatcaagtga gatcactgcg ccagatctag
    15781 cgatgtcagc tgttctgaca ggtgcagaaa tcttcttgcc gttagcagga ttgatcaata
    15841 ttgaagaaga aatcaaacga ttagaaaaag aactggaaaa gtggacaagc gaagtaaaac
    15901 gtgtccaagg aaaactttct aatgaacgtt ttgtttctaa cgcgccggaa gaagtagtag
    15961 aggcagagcg tgcaaaagaa aaagattatt tagagaagca aacggctgtc aaagaacgaa
    16021 tcgaaagttt gcgtactatt caataagaat agaaaaagag agtgtgaaat cagctagcta
    16081 ttactaaaag ctagctgatt gaacatcgtt acaggaaaga gtttgagcct cactcttagc
    16141 ttcgattcat aaggagatgt gacataaatt ttgtcgcatc tcttttttag tctactctta
    16201 ttatgtagga gaaggaggga ggtggatcat gtatcaagag tcaataaagt agttgataaa
    16261 atcgttcctc tctctgtttc ttttctcttt gtcatacttt tatttttctt atgtgttcta
    16321 tttgttataa taaaagagaa atgggggaat tgttgatgac gattgaagaa gcaatagaat
    16381 ggatccatag tcgattacca tttggttcac gtcctggcct tgaccgagtc gaagctttat
    16441 tagaagtggt agggcatcca gagagaaaag taaaaacgat ccatatcgct ggaacaaacg
    16501 gaaaaggttc tactgtagct tatttgagaa gcctattaga agaggctggg ctgacagtag
    16561 gtacatttac ttcaccttat atcgaaacgt tcaatgaacg gatcgcaatc aatggcaaaa
    16621 gcattccaga caatgatttg atccagcttg taaaaaaata tcagccactg atcaaacaac
    16681 ttgatcaatt tgaagcagta gctggtatta ctgaattcga gacattaaca gcaatggcat
    16741 ttgattattt tttgatgaag aaagtggacg tagcgattat cgaagttggc ttaggcggct
    16801 tattggattc taccaatgta gctgtaccaa tgctgacggg aataacaacg attggacttg
    16861 atcataccga aatacttgga gatacaattg aagaaatcgc tgcacaaaaa gctggaatca
    16921 tcaaacaagg cgttccagta gtaacaggaa atattgcccc agaagctttt actgtcatcc
    16981 aacaaacagc taaagcaaaa aatgcaccgc tttatgtata cggggaaaat tataaaataa
    17041 actatctgca tcctgatgag atgtggggag aagtatttga attttttaat gaaataggaa
    17101 agatccctca attaaccact ccgcttttag ggcaacatca agctgaaaat gcaggagtag
    17161 ccatcgaatt gtattttgtt tactgtcaat tggaaaagct gcctttccga gaaaaagatg
    17221 ttttgaaggg attgaagaaa tctcgatggc caggaagaat ggagcgtttg agtaacgagc
    17281 cattagttgt tttagatggt gcccataata cgcatgcaat gaaccggctt gttgagaatt
    17341 tgaaaaaaga attcaaagga tatcaaatca acattttgtt ttccgcctta cgaactaaaa
    17401 atgttagaga aatgctagaa cgattgcagc aagtaccaaa tgtccatatt tatttgacga
    17461 cctttgaaca tccaaaagcc atcgaattaa gtgaagtatc agatttagca agtgagagag
    17521 tatcaatcgt ttcattgtgg caattcggat tagcagatat attggaaaag atgacaaatg
    17581 aagacgtatt agttgtgacc ggttcacttt atttcatttc agaagttcgc catttattaa
    17641 tacaattagg aggagatcat gaagtataat gcagtgattt ttgacatgga tggtttgctg
    17701 ttcgacacag agttagtgta ttacgaagcc acacaagtag tagcagacaa gatgggtttt
    17761 ccttatgata aagacctgta tttaaaattc ttaggtgttt cagatgaaga agtatgggcg
    17821 aattatcata tgattttctc ggaatttggc aaaacaagtg tacaaagatt catagatgat
    17881 tcataccagg aaacgcttga acgtttttcg caaggagcgg tacaaatgaa gcccggtgtg
    17941 ttggaactcc tctctttttt agaagaacat cagattccca aagttgtcgc ttccagtaac
    18001 caacgagcag tcattgaact tttattgaag aagaacaatc tgtttgaacg atttgagacg
    18061 attgtttctg cagaaaatgt tcaacgagca aaaccagacc cagaaatttt cttgttagct
    18121 aatcagaagc taggtacagc gaagaaagaa acattgattt tagaagattc acaaaatggt
    18181 attttagcag cttctgcggc tgagatcccg gtagtcatgg taccagatct gcttccacca
    18241 tcccaagaat tgatcaaaaa aacagctggg gttgtttctt ctttacatga aatccctgca
    18301 ttgttaaaat aaaaatccat ctcttttcgt atcttatttt agataagata gaaaggagat
    18361 gtttttttgg gaaaacgatt gatcaaagaa gtacctacta gctctttacc aagggaacgt
    18421 atggaaattt atggcgcgga agctttatcg gatcaggagc ttttggcaat cttactgcgt
    18481 accggtcaac acccttatag tgtgatgtcg attgctggaa atctgttaaa aacgtttgga
    18541 ggactggcct ctttacgaca ggctactttg catgagttag aagagattcg agggatagga
    18601 cgcgtgaaag caatcgaaat caaagccttg atcgaattag gtcgacgaat tcagacggat
    18661 catgaaagag cggctccacc ggttcgtacc agctacgaat tggcccagca attgattctg
    18721 gaaatgaaag atcacaaaca agaacatttg gtttgtattt atttggacac gaagaatcaa
    18781 gtgatcttaa aaaaaacagt gttcatcggt tcgctgaatc agtcagtcgc tcatcctaga
    18841 gaaattttcc attatgctgt acgttattgt gcagcaagga tcgttttagc gcataatcat
    18901 ccttctggta atgttattcc atcgcagcag gatatgaatt ttaccaaaag gatacaaaag
    18961 tgtggagaaa tgatggggat cactgtactg gaccacttga tcatcggacg caaacgatat
    19021 tttagtttga gagaagaagg aatgatggaa gagaagtaag ttgctttctt gcaaaaaaaa
    19081 tgaagcaagt gtacaattat attgtaattt tgtttgggaa tagaagttga aacatctgtt
    19141 gcacctctat cgtacacgag caatgttaca atttaaatta gtgcttttgg cacgaggagg
    19201 atattattat ggaaaacgga acagtaaaat ggttcaacgc tgaaaaagga tttggattta
    19261 tctcacgtga agatggaagc gacgtattcg ttcacttctc agctatccaa ggtgacggat
    19321 tcaaaacatt agaagaaggt caagcagtga ctttcgacgt tgaagaatca gaccgcggcc
    19381 cacaagctgc aaacgttgta aaagcttaat tttatctgta aatcaaattg atggtagaca
    19441 tcaattttta cgagagaaca aagcgagtaa caaaaatacc tgccacaaga gacaatttct
    19501 cttgtggcag gtattttttt gtatgaaaaa
//
LOCUS       DAIGSZ010000057        19098 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.057, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000057 DAIGSZ010000000
VERSION     DAIGSZ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19098
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.057"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(224..454)
                     /locus_tag="NOB31_002104"
     CDS             complement(224..454)
                     /locus_tag="NOB31_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974298.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(890..1456)
                     /locus_tag="NOB31_002105"
     CDS             complement(890..1456)
                     /locus_tag="NOB31_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI0974299.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1456..2412)
                     /locus_tag="NOB31_002106"
     CDS             complement(1456..2412)
                     /locus_tag="NOB31_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HCI0974300.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2412..3068)
                     /locus_tag="NOB31_002107"
     CDS             complement(2412..3068)
                     /locus_tag="NOB31_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCI0974301.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3438..5456
                     /locus_tag="NOB31_002108"
     CDS             3438..5456
                     /locus_tag="NOB31_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0974302.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5526..5732
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5883..8297
                     /locus_tag="NOB31_002109"
     CDS             5883..8297
                     /locus_tag="NOB31_002109"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HCI0974303.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLSPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8645..10198
                     /locus_tag="NOB31_002110"
     CDS             8645..10198
                     /locus_tag="NOB31_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCI0974304.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10579..12363)
                     /locus_tag="NOB31_002111"
     CDS             complement(10579..12363)
                     /locus_tag="NOB31_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974305.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12378..14099)
                     /locus_tag="NOB31_002112"
     CDS             complement(12378..14099)
                     /locus_tag="NOB31_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974306.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            14199..14960
                     /locus_tag="NOB31_002113"
     CDS             14199..14960
                     /locus_tag="NOB31_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0974307.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15927..16195
                     /locus_tag="NOB31_002114"
                     /pseudo
     CDS             15927..16195
                     /locus_tag="NOB31_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16867..>19098
                     /locus_tag="NOB31_002115"
     CDS             16867..>19098
                     /locus_tag="NOB31_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974308.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6282 a         3390 c         3809 g         5617 t
ORIGIN      
        1 tcagtcacga tatcaaacaa aaaatatacg tctttcttca ttctagtttt cgcagcaggg
       61 attttaaagt agttcttatt agaatagtag agattaatta ataagctatc ttcgattgct
      121 aaaaagaaaa cttctgaatc ccacacctta taaaaatctt tgacaaatct attcgaagga
      181 tcaaatttaa accataattg cgtctcatta aaaagcataa ccattactcc gatctatttt
      241 taaacttagt ctctacctct aatatatatc gagtttttat tttgccttca gagaatactg
      301 tttctttttt tgcagttaca ggttgtttat tttcggaaaa agctaatata gctaaaattg
      361 aaacatccat ctggaattta tcttttttac tgctttgatc ataaaagtct gcatattcat
      421 cactgatatt ttttctaata aattcttcca tcataaaaat cacctcaaaa cgattatacg
      481 aacttacgtt cttgttgtaa agcgatattt gaggggcaaa aaaggggcat aatttgactg
      541 atattaagtt agctattgat atatgaatga catacaaaaa tataaaatct tttaaaaatg
      601 cttatatatc aatgtttttg ccattctttt atatatctgt tatacgtcaa aaaaatgtgt
      661 tcaatttcaa tttgtatttg aataaagagg ttgtgaaaaa gctgtcctgc atcaagtaat
      721 aagaacagcc aatcaaaaac agcttctcat gtttttgatt tggttggact tattaccgca
      781 gatataagct tttgagcacc gtgaataaag aggttatgaa atcaacgctc taacctgagt
      841 attagagaaa aaaacgcaaa acatatcatt tatgttttgc gttttttatt tatctttttt
      901 tctcaataca atataaaata ggcggctggt tcttttggtt gataaaccga taattcagca
      961 cattatatgt ttcctgtggc agtttggaac aaaaagaatc aaccatatcc agttcttttt
     1021 ctccaccttc atgaccatag tagacgacaa ggatcaatcg tccgcgaggc acaagtcgtt
     1081 tcaatatttc ttccatagct gtgcgtgtag tctctggcat agtgatgatt gctttatcac
     1141 tttttgggag ataccctaga ttgaaaatcc ctgctttgag attttgttgt tcagctatca
     1201 cttctcctaa cgtttcgtgg ccttgtagaa acaatgagac acgttcttct aactgacgct
     1261 gttctagcct ttcacgagta gcatcgattg cttgttgctg gatatcaaaa ctatagacat
     1321 gaccagtttt tccgatgtgt tctgctagaa aaaccgtatc gtggccattg cccatcgttg
     1381 catctacgac gtgatcccct ggttgcaaga tttcttgcag taatgtatgg ctgaaatgca
     1441 aagcagtttg caacatcaga cgctcacctt tttccgtaca tcatattttc cttggaagct
     1501 atctctgcga agaagttctt catcaattgc attcaagact tcccattttt tcaagctcca
     1561 cattggtcca atcaaggaat cccacggcgc atcccctgtc aaacgatgga tgatgatctc
     1621 ttttggtatc atttccagct ggtcgcaaat gacattgaca tagtcaggac ggctcattaa
     1681 ttgaaggcga ccttcatgat agtcccgcaa cattctcgtt ttgcgcatca gatgcatcaa
     1741 atggagcttg attccttgga tatctgaatc taaaatggtg cgtctgacat tttctttcat
     1801 catttctaaa ctttcgcctg gtaatccgtt gatcaaatgc gtacaaacac ggatattatg
     1861 tttgcgtaat ttagccacgc catctaaata agtttgataa tcatgtgctc ggttgatcag
     1921 ttttgaagtt tcttcaaaag ttgtttgcaa tccaagttct acccataaat acatccgctc
     1981 gttcagttca gcaaggtaat caactacttc atctggcaga caatccggtc gtgtaccgac
     2041 tgataatcct acgacacctg gtaaattgac tacttgctca aatcgttctt tgattatttc
     2101 aactggcgca tgggtgtttg taaaattttg gaaataaacg atgtattgtt ggacatgagg
     2161 ccatttttga tgcatcatgt cgatttcttt ctggaattgg attggaagag ggtcttcagg
     2221 tgcaacgatc atgtctcccg aaccagatac actgcaaaaa gtacaaccgc catgggcaac
     2281 agtcccatct cgattcggac agtcaaatcc tccatcgatc ggcaccttga aaattttccc
     2341 gccaaactca tttcgtaaag cgtaattcca agaatgatat cttttatttc cttctgaata
     2401 aggaaaagtc attaaaagtc cttctttctg taagagttat ctatttgttt tcttttttct
     2461 ctatacactg gataagtcag gcacagccaa gaaagactga gtaagtagcc gccgatgata
     2521 tcagtaggaa aatgaacgcc cagataaatg cggcttatcc cgacacttac tataataaac
     2581 atcatcagca attgaagcaa tgtgcgtaag gttctttttt gaacaaaagc tggaagcaga
     2641 aatagtaaag aaccgtaaag aatcatactg cctgctgcat gtccactagg gaaactgtaa
     2701 cttgtttcaa ctactaagtg cgccaatgaa ggacgctctc gcatgaaaaa tagtttgatc
     2761 accgggttga tgattccagc aattacaata aatccagaaa cgaaccaaaa tgtttctgcc
     2821 ctttttttct tataccacat ccataaagcc gcacaagcaa ataaaatgat gacggtaaga
     2881 ggattaccga atttagtcat aaagagttgg tagctgttca gatcaggata agaagctctg
     2941 acaatgcctg taaaccactg atcgaaacca gaaagccacg acagatggaa ctttacgatc
     3001 cagcccaaaa tgaaaaacag gacaagaaag aagctaccag ccacctgaaa tgatgtttta
     3061 tatttcatac aattcctcct ttgaagcaat gacttattat agcatttttg gtccagcgaa
     3121 aaaaacggta aagagataaa accaatgtat gattcctctt tgaataacca atattcttat
     3181 aaaaaaaata actgtaatcg gaaagacatt ttttggtaat gcaaatgaaa tgttagggaa
     3241 ataaaatcag tgtttttcga aatcctttta aacaagaacg tagacgtagg aagaacttga
     3301 aaatgaacag aagttgttca ttacggtaaa ttacaatatg attacaaaaa acaacaaagc
     3361 tcttaaataa cttttaataa atattaagag aagttataat tattaataat agataaattg
     3421 aagttggagg atagaagatg gaaaacattg caagaaaaga acggagacgt ttagaacaga
     3481 ccaaacgttt tcgaaaagca aaacgagggg cagcaatcgt gggaactgcg atggtaggct
     3541 gttctgtcgc tgccccatta gtacagccgg ttcctgttca agcggatgaa acacctgttc
     3601 agttcggcgc aagaatcaat acagcggcat ttatcacaga aattgctact tatgctcaac
     3661 caatcgctca agccaacgat ctatatgcat cagtgatgat cgcacaagca gttgtagaaa
     3721 gcggttgggg cagtagtgcg ttatctcaag caccttatta taatcttttt gggataaaag
     3781 gcagctatca aggacaaacc gtctacatgg atacgcttga atttttaaat aatcaatggg
     3841 taaataaaaa ggagcctttc cgacaatatc cttcttttgc tgaatctttc aatgacaatg
     3901 cctatgtact tagaaatact tcatttggca acggttatta ctatgccggt acttggaaga
     3961 gcaacacgaa atcctataca gatgcgacag cttgtttgac agggcgttat gcgactgatc
     4021 ctggttacgc aggcaaatta aataatatca tcgcaactta cggattgacc caatatgata
     4081 caccagctag cggaaacgca ggcggtggag cgactacagg tggcaataat actggaagtg
     4141 caggtagtac tggcggttca agcaattctg gtaatacaaa ctcaggttca gcaacttcga
     4201 ccacttatac tgtccaatct ggtgattctg tttggggaat ctcaaataaa ttcggtatca
     4261 caatggatca attgatccaa tggaacaaca tccaaaacaa tttcatttat ccaggacaaa
     4321 aactgacaat caaaggtagc caggaaaatg gctcttcgac gaataattcc ggtaacaata
     4381 ccaactcttc aggaaatgct ggtacatcaa acggaggaca aacaactggt gcgaaataca
     4441 ctgttcaatc tggtgattct gtttggaaga tctcaaatga tcacggaatt acgatggctc
     4501 aattgattga atggaacaat atcaagaaca atttcgttta tccaggacaa cagctaatcg
     4561 tatcaaatgg cggttcttct aatgctggag caaatactgg ctcaaatact gggaatacaa
     4621 gtggctctag ttcgtccagc tcaagttctt ctaatacagc ttcaggaacg aaatatacag
     4681 ttaaagccgg agactctgtt tggagcgtct caaataaata cggaattacg atggctcagc
     4741 taatccaatg gaacaatatc caaaataact ttatctaccc aggacaacaa ctgactgttt
     4801 caaacagtgg atcaacaaac agcacgtcag gtaatacagg ttcgtcaacc aatacaaata
     4861 acagcagttc agttaatact ggcagcagtt cgtctcaagg cacttatacc gtgaaagcag
     4921 gtgaatctgt ttggagcgtg gcaaataaaa acggcatcac gatggatcag ttaatcgaat
     4981 ggaataatat caaaaacaac ttcatttatc caggacagca attgatcgtt aaaggtggaa
     5041 cttcggcaaa tacaaataca ggttcaacta cttctgcagc gaaaccaaat acaccgaata
     5101 cgtctgctac gacaagtaca tcatccactg gtaatacgat gtataccgtg aaagcgggcg
     5161 agtcagtttg gagcgtagcg aacaaacatc atatcacgat ggatcagtta atcgaatgga
     5221 ataatatcaa aaataatttc atctatccag gacagcaagt gattgtgaag aaaggttcat
     5281 ctcaatcaac aaaccaacaa tcagttactg gttcgaaaac ctatactgtg aaatctggag
     5341 aatctgtttg gagtgttgct gacagtcatg gaattacaat ggctcaacta atcgaatgga
     5401 acaatattaa gaacaacttt atttatccag gtcaaacgtt gattgtagct aaataaaata
     5461 gctgttcgaa gaaataacga ttgaattcca caaaaatatt tgttactata aggctactta
     5521 aatatgacaa cacttgaaaa ggaagtagta aaaagactga agtttcagag agcgcatggc
     5581 tggtgagaat gtgcacggat gcttttgaac tcgcctttga gttgcccttg ctgaataccc
     5641 gagtaagcaa gcggcggtga cggccgttac aacgttcgag gccttttcac taaggtaaaa
     5701 ttaggtggta ccgcgtagat tacgtcctat aaaaagagca atctttttat aggatttttt
     5761 tatttctttt gtgaagtttg agaaaacaaa gcaaaaggaa ataaaaataa acagattctg
     5821 ccggtttttt cgttatattt ataatagaaa caagtgtttt caatagaaca ggaggacagc
     5881 aaatgagtta caatcataaa gaaattgaga aaaaatggca aaaatactgg gcaaaaacga
     5941 atactttcaa cacccatgat gatcctgaaa agccaaaatt ttacgcactg gatatgtttc
     6001 cctatccatc cggtcaaggg ctacatgtag ggcatcctga aggttatacg gcaacggata
     6061 tcctttcacg tgtgaaaaga agtcaaggat acaacgtgct gcatccaatg gggtgggatg
     6121 cattcggtct gcctgctgaa caatatgcgc tagatacagg aaacgatcca gctgagttta
     6181 cccaaaaaaa tatcgaaaca ttccgacgcc aaatcaattc tttaggattt agttatgact
     6241 ggaatcgcga agtgaataca actgatccgg agtattataa atggacacaa tggatcttta
     6301 cgaagcttta tgaaaaaggt ctagcttatg aagcagaagt agcggtaaac tgggtacctg
     6361 aattaggaac agttatttca aatgaagaag tgatcgatgg gaaaagtgaa cgtggtggct
     6421 atgatgtagt cagaaaacca atgcgccaat ggatgctgaa aatcactgct tatgctgatc
     6481 gcttattgga tgatctagaa ttagttgatt ggccagaaag cattaaagaa atgcaaagaa
     6541 attggatcgg tcgttcagta ggagcaaata ttgaatttaa agtggctggt acggataaat
     6601 cctataccgt atttacgaca cgaccagata ctctattcgg tgcaacttac tcggttcttt
     6661 cacctgaact agatcttgtt agagaaatta cgacccctga acaaaaagct gctgtagaag
     6721 cttatatcga agagacagct aaaaaatcag atctaaagag aacggatctt gcaaaagaaa
     6781 aaacaggagt atttactggt gcttatgcaa tcaatccagt taatggcaag gaaatcccaa
     6841 tctggatcgc cgattatgta ttatcttcat acggcacagg agccatcatg gctgttccag
     6901 cacatgatga acgtgacttt gaattcgctc aaactttcgg actagaaatt cttccagtta
     6961 tcgaaggtgg agatgttgaa aaagctgctt acacagaaga tggtacgcac atcaactctg
     7021 aatttctaga cggcatgaac aaacaagaag caatcgataa aatgaatgaa tggctagaag
     7081 aaaatggcgt agggaaaaaa gaagtcagct atcgcttacg tgactggcta ttctcccgtc
     7141 aacgttactg gggtgaacca atcccaatca tccattggga ggacggaaca gtcacagctg
     7201 tcccagaaga agagctacca ttacggttgc ctaagacaaa aaacatcaag ccaagcggta
     7261 ctggagaatc tccattagca aatatcgagg agtgggtcaa tgtcgttgat cctgtaacag
     7321 gtaaaaaagg ccgtcgcgaa acgaatacaa tgccacaatg ggcaggaagc tcatggtatt
     7381 acctgcgtta tatcgaccct cataacaaaa aagaactagc agattatgaa aagttgaagc
     7441 gttggctacc agttgacatc tacattggtg gagcagaaca tgcggtactt catttactat
     7501 atgcacgatt ctggcataaa ttcttatacg atatcggtgt tgttcctaca aaagaaccat
     7561 tccaaaaact atacaatcaa ggaatgatct taggcgaaaa caacgaaaaa atgtcaaaat
     7621 ctcgtggtaa tgtagtcaat cctgatgatg tggtcgaaac ttacggtgca gatacactgc
     7681 gcatgtacga aatgttcatg gggccattag atgcttcgat tgcttggagc gaaaatggct
     7741 tagaaggaag ccgtaaattc ttggatcgtg tatggcgttt gatcgttgat gagaacaata
     7801 aaatgcgtga ccgtatcact acattgaatg atggcaagct tgataaagtg tatcatcaaa
     7861 cagtgaaaaa agtgacagaa gactatgaaa atcttcattt caatacagca atctcccaat
     7921 tgatggtctt tatcaatgaa gcctataaag tggacgctct gccttatgaa tatatcgaag
     7981 gatttgttca actactcgca ccgattgctc ctcacatggg tgaagaacta tgggcaatcc
     8041 ttggaaatga tggtggtatt tcttacgcac catggccaac atacgatgaa gcagcacttg
     8101 ttgaagacga agtagaagtt gttttccaag taaacggtaa agttcgtgcg aaaagcaatg
     8161 ttccccgaga cttaggaaaa gatgagctag aaaaagcagc attagccaat gaaatagtgc
     8221 aagaatatat tgaaggcaaa acagtcagaa aagttattgc ggtaccaaac aagttagtca
     8281 atatcgttgc taattaattg gctctttgtc aataaggact gatgagttgt gcaaaatcaa
     8341 atctgggcca gaatgaactt cattctgtct cagatttttt gttatttcaa attgattaat
     8401 tgattgatca aaaaggtttt gattttcatg ttctcaaaca cgttcaatgt ctttttcttc
     8461 tgaatggtct tgtaagagat ctctgtaatc atcaaatttt tgtctattaa tcttagtatt
     8521 ttttgatgta taaactacct gaaattgaga gtacatacca aattcataaa ttttttatta
     8581 gtgggactag tgattgtatg gattttgacg cataatgaat gaagtatgag aaaaggagag
     8641 acaaatggat caagaactat ttattatcga agtattatca gctaaacaaa aaattatcga
     8701 gaaagcgaaa aaaagagcga aaagaataat gttcaagctt ttaagcttag tatttttctc
     8761 tggtttgctt tttttcggag ctgtatcgtt cctatatcgc catatgagtg cagtagtccg
     8821 ttcagctgaa gggatgcaaa aattaaataa tttgtatcac ttttcgtggg gagttggcgg
     8881 aataacaatt gttgtgctta ttgtttttct tctacttatt tggctccgtt accatcaatt
     8941 gtcgcgtcat ttcgatcaat ggcttagtca aagagcacaa cagtttttac ataataaacc
     9001 aacttctcaa gatgatgact atctttattt tgagaagact tcgacgagtc aagcttttcg
     9061 gatacaaaaa agtgattgcc agttattgct gagatcactt gatgatttac ctatctactt
     9121 aggcgaaagc aaatcaaaat tcggaatgaa cacattccat atttttttac tagaaaacga
     9181 acccagatgg gaaaaaagcc agtcttcgcc tggtggatac ctgacaacta agatgagtac
     9241 attagtcact ggttttttcc tcattctttt agctggaaca atctattatg ggagatacac
     9301 tcagccaaaa atgtcttctc atataaatgc tgcttctcac atgacaatga actcaactaa
     9361 cgatacgcat atacaaaaga caaatgaagg gttgttagct gatcctaagc aaaaggtaaa
     9421 tttgacaaca caaaagataa atgatctcaa acttgataca gagacgcact ctctctatat
     9481 gacaacagat agtggtgcta attgggtatt tgtgccgatt gattcgcaat ggttgcgttt
     9541 tggcgaatac accctgacaa cggggctgat tcctgaaggt tattggatgg acaacacata
     9601 tgatatttcc gccgatttct catggtttat ctattcttct ggggatgatg tacgtctgct
     9661 gacttcaaga gataatggta aaacatggca aacgtctatt atcacccaat cagttcagcc
     9721 gatacgttat cgaaaagcgg tattttatgg caacgatggt ctatttatct gtacatcagc
     9781 cagtgggatg tctgcagaaa ctttgtacat ttacactact atggatggcg gaatcacttg
     9841 gataaaaagt ggaagtacaa tgatcaatca gccagtacaa aatgtcagct tcgttacaac
     9901 ttctttaggt tttgtttcga cacgtgaaag tttgttttat acaaacaacg gaggacgctc
     9961 attcaaagaa tcagttctgt cgattccgga aaactatcag acagggggga tagatctttt
    10021 tcaatcacca aatgaagtta ctcaaataag cgcgaatacg ttagagacaa aattttattt
    10081 gttgaaaaaa ggaccaatcg atgcagggaa aatgtttgcc tgcctcttcc gttcaactga
    10141 taacggggaa acatggcaat tcgttcagca actatcgcaa gtagaacaag gagattaaag
    10201 aagagagatt gtgagcctga cgttcagcac cgagtcacaa gaaacaaatt caaaaaacag
    10261 cttctcatat ttgttgaata gtgtaactcg tgattcggag ttgacaagag caacaagaag
    10321 cgattttgaa gtatagcttc tcgtatttta caagatcgtg tcttattgcc gataggttgt
    10381 ctcttgaaca ccgtttattc gtaaaaaggg attgtgacaa gtcttttgtc actacttacc
    10441 gaacgaaact gaaggagcta tccaaaaagt atcattagta ttattctttg tgtttctagt
    10501 ggcaccacta gtacatttaa aaaagctatc gatcatggac taatcataca tgatcgatag
    10561 ctttttagat aatgtttgtt acgctatctg aaattgacta ttataaagac tggcataaag
    10621 cgttggtgat tggagtagtt cagaatgtgt tcctttttcg acgatatcgc cattcttcat
    10681 tacaaggatc atgtctgcat tttcaatcgt tgacaaacgg tgtgcaatca caaaacttgt
    10741 cctatctttt gtcacagctt ccattgcttg ctgaatcaat gcttctgttc gtgtatctac
    10801 gctagaagtt gcttcatcta aaataacgac aggaggattc gctagaatga ctcgagcaat
    10861 tgtcaataat tgttgctgtc cttgagataa cgtgccgttt tcgctagaaa tgatcgtatc
    10921 atatccgtct ggcagtgttc gaataaagtg atcacattgt gcgatttcag ccgcttcgat
    10981 aatttgttct cttgtggcat ccattttccc gtaggcgata ttatcagcta ccgttccttc
    11041 aaacagccag gtattttgta aaaccatccc aaaagaacga cgtagttctc cacgtgaaag
    11101 cttggtaata tcaagaccgt cgaattcgat ctttccttta ttcagttcat aaaaacgcat
    11161 cagcagattg actaaagtcg tttttcctgc accagttgga ccaacgatcg ctaccgtttg
    11221 ttttggcttt actgaaaaat cgacttgatt catcaatatt ttatctgatg tgtaaccaaa
    11281 ctgtacattt ttgaaagcta tttttccttt cggttgttct aaaagtcttg catctggaag
    11341 gtctggaatt tcatctgttt catctaatat ctcaaatatc ctatcgattg ctgccattgc
    11401 ggattggatc gagttgatca cataagaagc ggtagaaatt ggttcagaaa tctgattgat
    11461 gtactgaaga taagcttgta agaagccgat cgtcacacca cctgatagaa caagcatagc
    11521 accgaatacc gcacttatga tgaaggcgag ttgattaatg aaacgaatgg ccggatagat
    11581 agcacagttc ataaattgag cacgtttaaa agcgttgtat tgctttttat ttacttcgtg
    11641 tatagcagct tctgcatgag cttgctgatt gaatgttttg accactagat taccagctaa
    11701 gatttcttcc attcgattat ttaaaacacc cagttcatac tgattctgtt cagaaatctg
    11761 tttgtttttg ttcgcaatct tagttgtaac aattgaactg ccaacgatca gcaataagac
    11821 gagcaaagta agcttgcttt cgatataaaa cagcatcaga ccagcagcag ctattgttac
    11881 gacagaagta aaaaattgat tgatacctgt caataacact tgagaaagtt gattgagacc
    11941 ggtagttgtc cgactaatga tgtcacctac ttgatgattg tcaaaaaacg acatcggtaa
    12001 tgttttgaat ttttttgtga tttcttttcg caccctcaat gtgatctttt cgcttaacgc
    12061 tgccattgtc cgttcctgaa taaatgaagt gatgctgctt aagactgaac agccgatcag
    12121 caataagaca gggaacaaca atgcttgttt gatatcactg aaagaaagct gtccaatacc
    12181 tgtttttctt atttctgata agagatcatc gatcccgatt cccatgatca agggcatggc
    12241 tacgactaat aggttcccga ataaactgca tagaaacaat ccgtaaaaat atttatgttc
    12301 aggtttgatc attttccaaa aacgtatcaa agcacgcgtg ttcaacgttt ttttcttttc
    12361 catcgtatcc cttctttcta tattccttgt gattttgcaa actcctgata agtttggcaa
    12421 ttagacagta gttcttcatg agtaccttgt ccaacgattt ttccttcatc taaaacaatg
    12481 atgttatctg cttgttggat tgtactgagg cgttgagcaa caatcacgag agttttctcc
    12541 gacatgtgtt tatgaagggc tgctcttaat gctgcatctg ttttatagtc taaagcggag
    12601 aaactatcat cgaatacata gatctctgct ggtttgatca acgctcgagc aatacatatc
    12661 cgctgtttct ggccccctga ataattagaa ccgccttgag caacaaagct gtccaatccg
    12721 tcaggaaggg tgtccactag ttcttctaat tgagcgatct tgatcgcttt agacaactct
    12781 tctgttgagg catattcatt tcccatctgc aagttgctta aaattgtccc gctgaataag
    12841 aaagccttct gagggacata actgatgtgg gagcggatct gttcttgagt catttgagta
    12901 agaggaatac caccaagggt tacttttcct atcgtagggt cactaagtct caagagaagt
    12961 ttcgccaaac tactttttcc agatccggtc ccgccaacga tcgctgttgt ttttccttta
    13021 ggtattgtga aatcaatatc ttctagaact ggatcagaga tttcagtata tttaaatgtg
    13081 acatgttcaa aagcagctgc atttgtctga tcaaaggttg gttcagctac tgttttgatc
    13141 gtctcttcct caatttcgat ctctgcttgc agtatttctt ctatccgtcg taatgaggca
    13201 aacgatttag ggataatgac caataccata gctgcgatca tcaagtaagc aagtgtcagc
    13261 atagagtatt cgactacagc agtcacgaca ccgatttgta atgctccttc tgctacaaga
    13321 tttccgccaa accacaaaat agaagcataa acgattccca tgagcaaaaa agcaattgga
    13381 gtgacccaag caaatattcg gttcactttg atcatttgat tagcatagtc agcaaagctc
    13441 ttattcgttc gcttttcttc atatgattga ttatcaaagg cacggatcat attaatccca
    13501 gtaaagaatt ctctcaatgt gatggtgatc cgatccattt ttggctggat actcaaagat
    13561 aaaggtgccc ctcgtttcat cagtcgataa acaatccata cataaaaaac aacagagatc
    13621 aatgtaaccc atgttagtaa tagagaataa cgaaacatca tgagaatggt gaaaacgcaa
    13681 ataaccggtg ctggtaagat catttggcaa aataaaacaa tcatttgctg gacattatcg
    13741 acatcattcg tcattcttgt caaaagagat ccagaactaa aacgactgat atccttcatt
    13801 gacagctgtt ggaatttacg gaaatatttc tcccgcgttt ggaatccaaa cctagcggaa
    13861 gccaatgctg aaaagtaact agaggcaact gcagcgattg ttcctagaaa cgctacaagc
    13921 agcatttcaa ctccaatttt ttttataact gaggcttcgc cacttgctat acctgtgtcg
    13981 atcagctttg ctactaattt tggtacacct aatgtaccgg cgatttctaa acagatcatc
    14041 acaaaggtaa ggagagcgag tcctttgttt ttctgtaaga atgtttttaa gatagacata
    14101 ttattcctcc ttttttcctg atacttttcg attctatacc ttcaagtaac ttgaaggtca
    14161 atagaaaaaa gaataaactg aaaaagaggt gagaaaaaat gaaaaaaatg tatacgattg
    14221 gccaagtatc ggaactattt gatttgccaa aatcaacgat ccgctattgg gatgaacaag
    14281 gattaatccg ttcaagtaga caagaagaga atgattatcg attgtttgat atcgatgata
    14341 tttttatgct ttatgatatc gttttttata gaaaattaga tataccgatc aaacagatga
    14401 agaatttata tggaaaaaca ttgacggagt tatatgagac acttgatgaa acagaaagaa
    14461 gaatccataa agaactggtg gtgatgaaac aaaaacaaaa agagataagg gagcaaaaaa
    14521 aacagttgaa attgatgatc gatacaaacg aggaagaatt tcctgtagaa gagatccctt
    14581 ttgactgtat gatctcaacg gagtttgaag atattgtgga aatcaaaaaa tttctaccta
    14641 actattcaag ctttgggatg atgagtatgc cagcttccag ttcacagacg atgtatggat
    14701 tttttatcga ccctagtgaa gtacatttat ttactcaaga cgtgatttgg gagaaaaaag
    14761 atacggctgt ttatcgtcga ttcttattga aatccgagat gaaccatgcg gaacgtaata
    14821 atattttaga aatcagagaa agaatgtatg aaaaaggatg gaaaacagga gaagtgatcg
    14881 gccagtatct attgacgaat acggatgaaa acaatatcag aactgaatat tatcatgcat
    14941 ggatagaaat gaaaaaatag gaaatatgtg tttaagataa ctcgaaaatg atggttgttt
    15001 tagttataaa gaaaaatttt ctggttcgat tacgggttta atgtggggga ttattagtcg
    15061 tggatagata gaattttagt tttttagagg aaatatgtct ttaaaaatgg aatggttgca
    15121 attcttagcg atatatacga tgtaattgtc ctcttaaaaa agtatggaaa aataattgta
    15181 ttgggtgtta tgtataattc atggtgaact gagactaatg agaagaaaaa ttcatattgt
    15241 tatgagtgag attgtatcag atgagaatga taaattaaat aggtgcataa aagcattaca
    15301 cttaaaatac attgttgctt acattattac aatatgttaa taaggcaaaa ataaatagat
    15361 ggattgaata aacatatttt ttaatcaaat agtccctact gtgactttcc tcagctatcg
    15421 gtgatactac cgatagcatt tttttgctta taaaataatt ataagtattt agagattttt
    15481 cttctaacat tcttcaaaca agaaaaatca caaaggttat tgttattttt atatattctt
    15541 tttaagaatg attgtttttt tatagaaatt ttaaaaaata aaacacgtta ttgatggata
    15601 gttagtttgt tatttggtaa tattatagaa gttgactggt agtgatttat ttttcgtcgt
    15661 tttataaaaa tgttattttt tggaaaaatt cacaaatatg taacgaatgt ttttctggaa
    15721 tttgctgtgt taaaaagcag tatgactaat ataaatacta ttgtcattta tgcaattttt
    15781 tatggatagt aattttagag gggaatcaat gaaggaagaa tagaagggaa aaatagttgc
    15841 aaatacgcca gttagcaaaa atagcaatac atcttcaagc tttaaaattc gagagaatca
    15901 tcttggtagt ggaatcaact acaacaaaag gattaaacca attaatagat agaattacca
    15961 atggaaaaat agaaaaggta gttattctat acaaaagttg tttaattcgc ttcggttatg
    16021 aacttagtga aaccctttgc aatatatggt acagaatata gaaattattg acattacaga
    16081 aaatgatgaa gatttaatac agattgtcac tatttgtaga taccttttac aaggaaaccg
    16141 agccaataaa gctaagaaga tgattaagga gttgatggaa gacgatacaa gttaagaaag
    16201 tgaaactacg cccaaataaa gagcaaaaag agtaattgga cgtggaaaat gcaagaaatg
    16261 aaccatcgat tcggtggaca gtttattagt aatgacggtt tgagaacatc catgacgaga
    16321 atgaaggaac atcctaaatg cgtttagttg aaccaagtgc caaataatat ggccaaataa
    16381 gcgatcagtt atcgatgaat cccaagtatt ctaaactata tattcatttt gatgctaagc
    16441 attgatatat ttttttggga ttgatgaagg ttaaccaata cagggactca ctgatgaaat
    16501 tctagagtct gaccttggta tcaacgattt agtgattgtt tctaatggaa aagtataaaa
    16561 gtatataagt acattaacaa aataactatt agggttacgc tccagcttgt gcaaggcact
    16621 ggcaggagga atcgtgaaat cataattatg gttaagccac acggacaact aaaagtcata
    16681 caaagctatc gaatcaatca acagaagaca atcggcaatc attagctttg tttacagctt
    16741 acattgcaac gcttgagttg aaccgaaaat acgagggagg taacgcagcc attttgagtt
    16801 ggggaatctt tttagaaaat tatcgggtac cttgttgttt agtcaaaatt ataaggggga
    16861 gtaatagtga ggaacaaatt tcataaactg ttaagtatgt ttctagttat gcttattgtg
    16921 atcaatcaat ttgggaacat aacggttcta gctgagtctt tagcagaaca gccagagcgt
    16981 tcgctgacga tcgaagttga tcaagaggag gctgctttgg gtgagcagtt ccagttgcga
    17041 gtcagaggaa caccagacct gctaaatgca ttggtcattg ataagagtga ggatttgatt
    17101 gaaggggaag tgaagcaact caatgattac gaacgtctga ttacttattc ttcccagcat
    17161 tcaggtaaat acgaattgac cgcaagaagc ggtgatattc aatcaaatac ggtctcaata
    17221 gaaatcagtg taccagaaga aagcacaagt gagtctttta atgtaccaga agaaagcaca
    17281 agtgaatctt ttaatatacc agaagaaagc ttaagtgaat cttttaatga agccagatca
    17341 tctgagccat ctataacgca ggaatctcag attgaaagac aagaggagct cttgaattat
    17401 gacatcggca tctctgctga gcgccccact ttgccgagca ggcatacaca aacgttaaag
    17461 ggatacattc aaggaggcgc tggcgatatt cttgaagaat atggggagat ggtcgtacga
    17521 gttcctagag catcgattgg cttaattgag ttcattagag tggaggtcgc tgatgattca
    17581 cctttaaagc cactggcatt ttaccaagaa ggcacagacg ttgtttttcc atttaccttt
    17641 gattatgaag gattaaatga agccgctcag tcgtatacat tcagtatcac gtttgaagtt
    17701 gctttctttc aatcaggcgg tactgagcca aataatgact ttcaagtgag tcttacttat
    17761 gctgagcgag cagcaaacac ggaattttca attacgccta ttccttcatc aagacccatt
    17821 ttttcgaaat tatactatgg ctctagagaa atcgacagcc aaggaaatct tgggaatctg
    17881 ctgattgacg ggcaagacgt gaccaacagt aataaattta ttttgcaggt aaattatgaa
    17941 ggatcacgaa aagacggtgt agtggttacc gatgtactac cgcaaggaac aactttggca
    18001 ccgaatccga ctacatggag ttccactgga aatagagaac ctatttcagg tggggttcgg
    18061 atcgcagaag taacgaatcc aggtgaagca aacgttagaa ctcattatgt ttccgaggaa
    18121 tttgtggaca aagtatcttt taataaggaa acgaatacac ttgttgtgga ctttggtaat
    18181 ctagcagagg gtcaatcgta ttttattgaa tatgctcttg aagtgaccga tgtcgacttg
    18241 ttcaatgaag gaagacaaga ggatgggttt tctcggaatc gagcgagtat gacctacaat
    18301 aatcaggtaa tgagccgaga ctaccgcttg agaatccctg aaagtaatct tccggcaatc
    18361 tctttaagaa aaagtgtgga caaaaatgtt atcaatctca atgaaaatga actaacgtat
    18421 actctgcatg tctcgatgtt ttctggaaca agaaatacgc ttgttattga agatgttttg
    18481 gaagaaggca tggaatttgt gtcatttcta tcagatattc cctctttcat tgatgccgaa
    18541 gtcaataatg gaatagttcg tttcagtgcg aataatacga ttggtggtcc gacaagtttt
    18601 accctctctt ttaaggtcaa tgtagaggcg tatgcggtcg gcgatcaaat tttaaacttt
    18661 gcaacgcttg tgaatagtga caatcgattg aatacgagta ctgtaagaac aaggaaaatc
    18721 gatgggcgta ttaaagtaat taaaactgat gagaatggcc aaaggctggc aggagcaaaa
    18781 tttgaaattt tatcaagcga ttcacaagtg atacaagaag gtataacggc agaaaacgga
    18841 gaatttttaa gtgaaccgct tcctgtaggt agctatcaag tccgagaaac agaagcaccg
    18901 gaagggtatc ttttagatgc gacggtacat gatgttttta taaatgaata ctccatagaa
    18961 gaagtgacgt taaccattga aaacatcctt gatacgggtg gtgttgaact aattaaacat
    19021 gctgaaggca gtggtgaagt ccttcaagga gctgtttttg agttacagaa ccgagaagga
    19081 gaaacgctac aaaccggt
//
LOCUS       DAIGSZ010000058        18618 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.058, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000058 DAIGSZ010000000
VERSION     DAIGSZ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18618
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.058"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            299..1960
                     /locus_tag="NOB31_002116"
     CDS             299..1960
                     /locus_tag="NOB31_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0974309.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2377)
                     /locus_tag="NOB31_002117"
     CDS             complement(2030..2377)
                     /locus_tag="NOB31_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HCI0974310.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2461..3402
                     /locus_tag="NOB31_002118"
     CDS             2461..3402
                     /locus_tag="NOB31_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0974311.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3403..4446
                     /locus_tag="NOB31_002119"
     CDS             3403..4446
                     /locus_tag="NOB31_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0974312.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4452..5522
                     /locus_tag="NOB31_002120"
     CDS             4452..5522
                     /locus_tag="NOB31_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974313.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5512..6465
                     /locus_tag="NOB31_002121"
     CDS             5512..6465
                     /locus_tag="NOB31_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0974314.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6477..7487
                     /locus_tag="NOB31_002122"
     CDS             6477..7487
                     /locus_tag="NOB31_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0974315.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7772..8593)
                     /locus_tag="NOB31_002123"
     CDS             complement(7772..8593)
                     /locus_tag="NOB31_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCI0974316.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8690..8968)
                     /locus_tag="NOB31_002124"
     CDS             complement(8690..8968)
                     /locus_tag="NOB31_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974317.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9236..11245
                     /gene="metG"
                     /locus_tag="NOB31_002125"
     CDS             9236..11245
                     /gene="metG"
                     /locus_tag="NOB31_002125"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HCI0974318.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11724..12311)
                     /locus_tag="NOB31_002126"
     CDS             complement(11724..12311)
                     /locus_tag="NOB31_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974319.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12486..13808
                     /locus_tag="NOB31_002127"
     CDS             12486..13808
                     /locus_tag="NOB31_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0974320.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13963..14739
                     /locus_tag="NOB31_002128"
     CDS             13963..14739
                     /locus_tag="NOB31_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCI0974321.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14732..15301
                     /gene="rnmV"
                     /locus_tag="NOB31_002129"
     CDS             14732..15301
                     /gene="rnmV"
                     /locus_tag="NOB31_002129"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HCI0974322.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15294..16178
                     /gene="rsmA"
                     /locus_tag="NOB31_002130"
     CDS             15294..16178
                     /gene="rsmA"
                     /locus_tag="NOB31_002130"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HCI0974323.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16629..17258
                     /locus_tag="NOB31_002131"
     CDS             16629..17258
                     /locus_tag="NOB31_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974324.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="NOB31_002132"
     CDS             complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="NOB31_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HCI0974325.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
BASE COUNT         6081 a         3347 c         3786 g         5404 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgtggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt ttttcatttg attgctcctt tatttttggt
     2401 tcattatcta ataatgtagc gaaacatctg tcagaagtca aaagctaggg ggaaacatta
     2461 gtgaatagtt atatcaaata tgtattaaaa cgtgtctttt tcatgatcat cacgctttgg
     2521 ttaattgcaa caatcacctt tttcttgatg caattgctgc cgggcacgcc atatacgaat
     2581 caggaacgtt tgagtcctga aacaatcgag atgctaaata aacaagtcgg tttggataaa
     2641 ccagttatcg tacaatatgg gatttatctt tctaatttgc ttcaaggaga ttttggaatt
     2701 tccttccaat ttaaaaacca gccagtcgca catttgttag ctggaagaat cggaccatcc
     2761 ttgcagttag ggttacaggc aattatcttt ggaacagtcc tagggacgat tttaggaacg
     2821 atctctgcca tgaagcaaaa tacatgggca gatacatctt ctacactcgt agcgatatta
     2881 ggtcgttcca ttccaaactt tgtatttgct gttttattac aatatatctt tgcaatcaaa
     2941 ttacaagttt tgccaatcgc aaaatgggat ggctttgtgt acacaatctt accaacaatt
     3001 gcgttggcca tgtcgccgct tgctgactct gctcggttta tccgtacgga aatggtggaa
     3061 gtactgcata gtgattatgt ggaattagca aaagcaaaag gattgagccg ttgggaaatc
     3121 gcctttaaac atggtcttcg aaatagtttg attccattga tgactttatt aggaccgtta
     3181 gctgtagcat tgatgaccgg atcactggtg gtagaaaata tctttgctat tcctggtatc
     3241 ggggaacaat tcgttaagtc aatcacaaca aatgattatc ctacgatcat ggctgtaacg
     3301 atcctttact catttatgct gatttttgtt attttgatcg tggatctatt gtacggtcta
     3361 gttgatccaa gaattcgtgt ttcagaaggg agccgaggat aaatggaaat gataccaaag
     3421 cgttatgaaa cagttgcaga tatccctgcg gatgaatttc ttccattaca aaaaaatacc
     3481 gaagaagaac gtgaacagat tactgcacct tctttgaatt ttatccaaga ttcatggcgc
     3541 cgtttaaaga aaaacaaagc tgccgttatt tcaatggttt tactattggt catcattttg
     3601 atctctgtga tcacaatctt tgtttctcct catgatccaa ctgcccaaaa cgtggcttat
     3661 atcaatttgc ctcctcgtat tccgggaatc aatatcgatg gattgaatgg aaaagcaatg
     3721 gttggtggtg aacttgttga taaatatgct caagcaaacg tcccttcaaa cgtaaatttc
     3781 tttttaggaa cagacggttt gggacgtgat gtattaagcc gcttatttat gggaatgaga
     3841 atctcgttgc tgatcgcatt tattgctgca ttactagatg taacgattgg tgtagcttac
     3901 gggttggttt ctggtttgtt aggcggacgt gtcgataacg tgatgcaacg ttttttggaa
     3961 atcttatcag gaattccaaa cctcgttgtc atgattttga tgttggtcgt ttttgaacca
     4021 ggaatttttt caatcgtggc tgctatggcc atcacaaact ggataccaat ggcacgtatc
     4081 gttcgtgcac aaacaatgaa attaaaagat caagaatatg ttttagctgg attgacatta
     4141 ggtgaatcaa gaatgaaaat tgcattcaaa catattttgc cgaatatctc tagtgtcatt
     4201 attattcaaa tgatgtttag tattccatct gctattttct tcgaagcctt tttaagcttt
     4261 atcggtttag gtcttacgcc tccgtcagct tcattaggaa cgatgttgag cgaagggtac
     4321 aagacattcc tgtatctgcc ttatctatta tggattccgg cagtaacttt atcggttatc
     4381 atgattggct ttaacttact tgctgatgga ttgcgtgatg cctttgatcc taaaatgaaa
     4441 gagtgaagac gatgacgaaa attttagaag tgaaagactt agaaatctct tttgatacgt
     4501 atgctggaaa ggtacgagcg attcgcggtg tcaattttca tttgaataaa ggagaaacat
     4561 tggcgatcgt tggggaatct ggaagtggaa aatcagtgac gaccagaagc atcatgcgct
     4621 tgctgtcaag caacgccaat atagatgctg gtcaaatcct ctttaaaggt aacgatatcg
     4681 ttggaaaatc agaaagagag atgcaaaaaa tccgtggtaa agaaatagcg atgattttcc
     4741 aagatccaat gacctcttta gatccgacga tgcccattgg gaagcaagtc gctgagtccc
     4801 ttagaaagca taataaagtt tcaaaaaaag agggacaaaa agctgcatta gaattgctta
     4861 aattagttgg aatacccgaa gctgagaaac gtatcaacag ttatccgcat cagttctcag
     4921 gaggtcagcg tcaacggatc gtgatcgcga ttgcactggt atgttatccg gaaatcctga
     4981 ttgctgatga acctacaaca gcgcttgatg tgactattca agcacagatt ttggagctgc
     5041 tgaaagaaat tcagacaaaa atcgatacat caattatctt tatcactcat gaccttggtg
     5101 tagtagcgaa tgtcgctgat cgtgtcgctg tcatgtatgg aggaagaatc gttgaagttg
     5161 gaacatcgga agaaattttc tacaacccgc aacatcccta tacttgggga ctgcttggtt
     5221 caatgccgac attagatagt gcgaacgatc gattgtatgc tattcctggt tctccaccgg
     5281 atttattgaa cccgccaaaa ggagacgcat tctatccaag aaatgaattc gcgatgaaaa
     5341 tcgatgcaga acaagaacca ccattttttg aactatcaaa aacacacaag gcagcaactt
     5401 ggctacttgc tccgcaggca cccaaagtga caccgccaga agaaatccaa cgtcgctggg
     5461 ctatctttaa agagaaacaa aaacatactt acggtcaagg aggaattgct gatgccaaat
     5521 aaactacttg aagttaaagg attgaaacag tatttcaatg taggaaaaaa gaatgaagta
     5581 catgctgtaa atgacatcag ctttcacatt tatgaaggag aaacattcgg tttagttgga
     5641 gaatctggaa gcggaaaatc cactactggc cgtacgatca ttcgcttgaa tgaacctact
     5701 gatggtgaga tattattcga cggtcaagat ataacgaaga tcaaagataa aaaaggtttg
     5761 acgaaattcc ggcatgatgt tcagatgatc tttcaagatc catacgcttc gttgaatcct
     5821 cgtatgaaag tcagagatat cattgccgaa ggaattgatg ttaatggact agctaaatca
     5881 tctgaagagc gtgcaaaaaa agtcgatgat ctattgagaa ctgttggatt gaatccaagc
     5941 cacggtactc gttatcctca tgaattttca ggtgggcaac gccagcgtat tggtattgca
     6001 cgagcattgg cagtaaaacc gcgttttatc atttgtgatg aaccaatttc tgcactagat
     6061 gtgtcgatcc aagcccaagt ggtcaatttg ttgcaagatc tccaaaaaga acatcaattg
     6121 acctatctat ttattgcaca tgatttgtcg atggttaaac atattagtga ccgaatcggt
     6181 gtaatgcata acggcttgtt attagagatg ggaacaagtg atgaaatcta taatcacggt
     6241 gttcatcctt atacagaaag tttgttatct gctattcctc taccagatcc agaccatgag
     6301 agaaaacgca gaagaatcaa atatcaacct gaaccagatg acggacaagt acgtcaactt
     6361 cgtgaaatcg caccagaaca ttttgtctat gcaactgagc aggaagtccc atattacgca
     6421 aaaaaactaa aacgacaaaa ggaatctctt ctggttgcta actaggaggg acatagatgc
     6481 taaaagcttt taaattccgt atgtatccga cagaagaaca aaaacagcaa ttgattcgta
     6541 cttttggatg tgctcgattt acctataacc atttgctgaa aaagcggcag aaaagttggc
     6601 aacaaacagg agtagccaat ttttcgctca cacccgctac attaaaaaaa gaatacccat
     6661 tcttaaaaga agtagacagt cttgctttag caaatgcaca gcttaatttg gatcgggctt
     6721 ttcgcaatta tttcaaggga cgtgccagct tcccaaagct taaaacgaaa aaaagtatgt
     6781 ggcaatctta tacgaccaac aaccaaaccc gtacgatcta tctggaaaat ggctacttaa
     6841 agttaccaaa acaaaaagaa ctaatcaaga taaatcagca tcggccagtt gaaggatcga
     6901 ttcgctccgc tacgatttct gctcgatata atgaagaatt ttatgtcgca ctactttgtg
     6961 atgtttcgcc agtaaaaaaa gaatctttag ctaaatggat cgggatcgcc tatcatccga
     7021 agacattgat ccaaacatct cgacctctag aagtaacttt accaaaattt caccagacag
     7081 aagaaaagct gcaacatgca cagcggaaat tgaatgtgaa agtccgctcc gctcaccata
     7141 gaaagatcag gttagatcag gcaagcaatt atcagaaaca aaagagaaaa gtaatggatc
     7201 tttatctgaa acaaaagaac cagcgagaag attatcttga acaattatct gggaaattgg
     7261 tcaaacaata tgactactta tttgtagaat cttttccaaa agaagaggca catgctgatt
     7321 tttctattca cgactggcat aaattaataa caaaattgcg ttataagtcc caatggtata
     7381 ataaaaaatt tcttttgatc aataccgacg gagcagaaga aagcaattcc gtaagaaaga
     7441 gccaagtagt agaaaaaatg ggcagacatt cggttatcaa gggataaaaa atgaatgaaa
     7501 ctgataggag cgttagggtt agccttgtta ataaaaagtc ttaatgactt ttgtttctag
     7561 gaatttttct tttgaagaaa agctcactaa ttatgacaaa ccaataaaac aatagcagaa
     7621 aaagttcgta cgagcttttt ctgctattgt taatttttta ttcagaaagt ttacgaatac
     7681 atcaaaattc tgaaacaaaa aacgtaactc acaaagagtt gtttttgcgt tttttcttga
     7741 atgattaggt ctgaatcttt tgctcacaac cttattcatg gtgccccggc ttgagctgat
     7801 agatttttga aggacggccg attcctacag gacgttcacc gatctcatcg aaatattgga
     7861 gcatagcttt cttaaaattg gaatgatcga tcgttttata atcgatccct aagaatttag
     7921 caaatacttt tcgagcttcc gtaatcgtga aatctttacc taaaacttgt agaacttgcg
     7981 gctcgtgttc cattttattg actacacggt tgaatgcttt caagatgatt tgactatggt
     8041 caaaagccaa agtatctttg ccagaagact ctccagtgac taaatcaagc gagatagcca
     8101 cttctccgct agataaatgg atcttgttac tatgacgttc tagtgtgaac cagcgtactt
     8161 ccttggcatc atctccggcg attagcggtt cttctccaat aaaggctaag tagctgactg
     8221 tgacgaccca gcctcgcgga tctcgattag gcgtactgaa tgtatgcagt tgctcaatat
     8281 tttcttttga aataaccaca ccagtttctt cctttgtttc tcttaagacg ctttctccag
     8341 ttgactcatc cttttggaca aagccaccag gcaatgccca tgaatttcga taaggatgcc
     8401 cttttctttg gatcaacaaa actttcagct gatcttcttc tttgttatag cacatcagta
     8461 cgatatcgac agtcaaagag ggcttgtcat attctggacg ttcctgtttt tgataccagt
     8521 taagaaattc ttcttcactt gctttatgtt cataatataa tttttcttct tctttagaag
     8581 caaaacggtt catctgacca cctccattga cagtaaaagt actttttacc ttattgtagc
     8641 agactctgaa aaaaaaccaa ggatttactt gaaaaatcta ggttatcatt taaatatgaa
     8701 aaataaatgg aagtatgaga ttgaataaaa agaaaagcag ataaaacggc aatactttat
     8761 accgctcttc acgaatggca aagaagccac aaataacgat atatacgtca atgataaaac
     8821 gcaaaatcca agctgctgtc ataaaactgt tcaaatgccc atggaggtta aaataaccat
     8881 acatacgaat ataaaaatag ctgaatatta aatgtgctaa tgaaagaaaa gcaatactaa
     8941 gtgtaaaaaa aagatgtttc ttctgcatga ttgttccagt cccttactaa gatagatagt
     9001 ctttattata ccacgtgtga ggggagaaat aaaaagccgt tttttagtag atatgaaaca
     9061 aaacaaaaac ccgcatttat tcaacctatt catcctttta aaggatagat tgaacgtaga
     9121 tagaagtcgt ttatccagtc tttttcattt tgaaaaaaag ctaacagcat gcttttttta
     9181 tggtatacta gcaaggaaac gaattcgcat catgcgataa aggaggaaga gccccgtggc
     9241 agaaaaggaa actttttata tcactacgcc aatctattat ccaagcggca aacttcatat
     9301 cggcaactcg tatactacga ttgcatgtga cgcaattgct cgttataaac ggttgatggg
     9361 ctttgatgtg ttttatctca ctggagtgga tgaacatggt caaaaaatcg aaacaaaagc
     9421 agaagaacta ggtgtaaaac cgcaagaata tgtagataaa atggcggctg atgtcaagaa
     9481 attatggaaa acgcttgata tcagttatga taaattcatt cgcacgacag atgattacca
     9541 taaagcagct gttcaaaaaa tatttgatcg tttattagaa cagggagata tttacttagg
     9601 tgaatatgaa ggctggtact ctgtttctga cgaagaattc tttacagaaa cacaacttgc
     9661 agaagtgtac aaagatgacg aaggtaacgt gatcggtggt aaagcgccaa gtggacacga
     9721 agtagaattg gtaaaagaag aatcatactt cttccgcatg agcaaatacg cagaccgtct
     9781 attggaatac tatgaagaac atcccgaatt catccagcca gaatctcgta aaaacgaaat
     9841 gatcaacaac tttatcaaac caggattaga ggatcttgca gtttcacgaa caacttttac
     9901 ttggggagta ccagtcaaga gtgatccgaa acatgtggtg tatgtatgga tcgatgcatt
     9961 atccaattat attactgcac taggatatgg ctccgaagat gaaagtctat tcgaaaaata
    10021 ctggcctgca gatgttcaga tggtcggtaa agaaatcgtt cgctttcata cgatctattg
    10081 gccaatcatg ctgatggccc ttgatttgcc tctacctaaa aaagtatttg ggcatggctg
    10141 gctattgatg aaagacggaa aaatgtctaa atcaaaagga aatgtcgttt atcctgaaat
    10201 gcttgtggaa cgttatggtt tagatgcact ccgttattat ttgcttcgtg ctgttccgtt
    10261 tgggtcagat ggtgtcttta cgccagaaga ttttgtttcc cgtgtcaatt atgatctggc
    10321 aaatgatcta gggaacttat tgaatcgaac gattgctatg atcaacaaat attgtgatgg
    10381 actcgttcct gactatgcct cacttgtcac tccatttgat agtgaactgt ctacgacggc
    10441 tgctaacgtt gtcggacgtt accatgatgc aatggaaaaa atggaattca atacagcatt
    10501 ggctgaaatc tgggtgctga tttctcgtgc aaacaaatac attgatgaaa cagaaccatg
    10561 ggtattagca aaagacgaag aaaagaaagc tgaattgaat agtgtcatga tccatttagc
    10621 tgaatctttg cgtatcgcag cgatattact tcagccaatc atgacagaaa cgccagagaa
    10681 gatcttcaat caactaggat tggactctga aacaatgaat cttgaaggat tacactttgg
    10741 cgaatttcct tcaggaacaa aagtagttgc aaaaggtaca ccaatcttcc cacgtttaga
    10801 tatggaagaa gaagttgctt ttattcaaga aaaaatgtct gaaggtactc aaacaaacga
    10861 agatacagtc aaatgggatc cagaagaaac agaacttgtt tcaacgaaag aaaaacaaat
    10921 caaatttgat gtatttgaaa aagtagaact aaaagtagca gaagtcatca actgtcaaaa
    10981 agtagaaggg gcagataagt tgctgcaatt ccgactagat gctggagaca gccaagaccg
    11041 tcaaatcttg tcaggaatcg ctgaatttta tcctgatcca agcgaattga tcgggaaaaa
    11101 agtcgtcatt gtagcaaatc tgaaaccacg aaagatgcgt ggacaaatca gtcaaggaat
    11161 gatcctttct gcagaagcac cagatggctc tttacaagta atcgaagcac caaaatccat
    11221 gccaaatggc tcagaaatcg catagaaatt caaagggggt atgacactag ttgtgtcata
    11281 cccccttttt ccgaaatttg agaagcaatt ttcgtaaatt ccttcttatt acttgaagcc
    11341 aatcatataa tacagaaaca gagaactatc caaaataaat cctagaaaaa gaagtacgag
    11401 cttcgctgat ttttgttaat ttagaataat actaatagga atcgtaaaaa cagaaaaaaa
    11461 gcataatgat aaagggtcgg gcagatttta attgattcat ctggtactct tttttattgt
    11521 ccttacattc ataaagtttg aatgcaatga ctttattaca tctatattta tatctaacag
    11581 tagcgttgat gtgttaatta taagttctat cactttatgt tcaattagtt tgtgctctta
    11641 tatgtgtgat tgaaaatata gataaaaaaa caatcatcgg ctttgacttc gatgattgtt
    11701 ttctttattt tgtaaaaatc ctatcacttg attttatggt aaccttttat ttttgtcttc
    11761 aaacggcttg gtaagagagc agtaagcagt gcaaatggga tcgaaaagac ataccagaaa
    11821 atcgtacgtc cgataccata atgttgatag agctttgtca acatcacgtg taacaagatc
    11881 aaccctaaaa gcaaggagcc agctataaac caatgattat cccaatgcat gacttcacta
    11941 agtgccatca ctccaaaagg atagaaataa aaatagatcc cgactaaggt catccgccag
    12001 ttctttgtaa atgttccgat attcaataaa aagaaaatcg ctgaaagcaa aataccgata
    12061 ggcggaaaaa gcccaaccaa aaaggaatac aacatccccc acaagatcat cacaggacct
    12121 ttgatcaatg caacgattgc gatgaacaaa gtcagcaata ttagtttttg tgataacgtt
    12181 gcaacagtca ttaatccaaa taaaattaat gtgaaccaat gccaatggga ctgctgttgt
    12241 tctttacggg aaaaatcgac ccggttggat aaataatctg ctaatttcgg ataagaacgc
    12301 ttaaaatcca taaactgttc ctccttcgtg gaaaaggtag gtttagtata cgaaaaataa
    12361 aaaagaaata catccgtctt aagagggagt ttttcactga aagtggagaa aaaagaatgg
    12421 taaattaaaa tattctcagt tatactgaaa attataccaa atttcaaaga agaaagagga
    12481 tgggaatgaa aggcaaacta aaacgagaaa tcaatctgtt tggcgcatta gctaccgtta
    12541 tgggaaccgt gatcggtgca ggcgtcttct tcaaaactgc tgctgttact gctagtactc
    12601 agtctacaag tttgacattg ctagcttggc ttttgggtgg tttcttaacg atctgtgctg
    12661 gattgacagt ggctgaatta gctacagcaa tcccggaaac tggtggagct gtaaaatata
    12721 ttgaagctgc gtatggaaaa ttgcccagct ttttattagg atgggcgcaa agcttgattt
    12781 actttcctgc taatattgct gcattatcga ttatctttgc gacacaattg acgaacttat
    12841 tacaattatc taccgattat cttttgttga ttgcagtgat caccgctgtt tctgtgacag
    12901 ggttgaattt gttagggaca aaagtcggtg cttctgtaca atcagtgacg ttgattgtta
    12961 aattaatacc aattgctgtg attgtcatat ggggattatt gaccccagga caaggaactg
    13021 tccagttatt tccaatcgaa gctggaaaag atgttacttt tgtcgaagga ttgagcagtg
    13081 cgttgttagc aacgttgttt gcttatgacg gctggttagg tgtcggtgca atggcagggg
    13141 aaatgaaacg gccggaaaaa gatttgccta aagcaattat tcttggtttg agttttgtaa
    13201 cagtcgttta tctattgatc aattttgttt ttttgaaaac tttgccgatt gatcatcttg
    13261 ccggtaattt gaatgcagct tctgaagcat cagacgtcat ttttggagga atcggtggaa
    13321 agctggtcac tattgggatc ttgatctcgg tatacggtgc attgaacggt tatacactaa
    13381 ctgggatccg cgtgccttat gcgatggctt tagaagacga gctacctttc agtaaacagc
    13441 tgacaaagct ttcaaagaag tttacggttc cttatgttcc tgcggttttc cagttagcag
    13501 tagcttgtat tatgatgagc cttggttctt tcgacttttt aacagacatg ttgatttttg
    13561 tgatgtggct attcagttta ctgattttta tcggtgtctt tattttaaga aaaaaagcgc
    13621 cggaattgcc acgtccatat aaagtaccac tttatccaat cgttccgatt attgcgattc
    13681 tcggtgctat tttcatttta ggtatgacga tgatgacgca aacgaaatta gcattgatcg
    13741 gtataggtgt taccttgata ggtatcccag tctattatca aaaaaagaaa aaacgctcag
    13801 aagagtaaaa tatttcaaca acagacagaa aaagtacgaa ctaggtcctc tagatcttcg
    13861 tgctttttct atttcaataa aacaagttct tctattttga tttttgctac ttctgcaagt
    13921 agtgcttatg tgctaaagta agaatgaaaa ggagagataa acatgatatt tgattctcat
    13981 acccatttaa atgctgaaca gttcaatgaa gatattccag aaacgattca gcgagcacaa
    14041 gaaatggggg taacgaaaat ggcggtcgtg ggcttcgata cgccaacgat tgaaaagtct
    14101 ttgcaattaa gccatgacta tccaaatata tacagtatta tcggctggca tccgacagag
    14161 gctggcagtt atacgaaaga aatcgaaaat aaattacaag aacaattgac tttaccaaag
    14221 gttgtagcat taggggaaat tggcttggat tatcattgga tggaagaccc gaaagaagtc
    14281 caagataaag tatttcgcag acagattgct atcgcaaaag aaatgaacct accaatcagt
    14341 attcatacta gagaagcact tgaagacacg tatcaaatcc taaaagaaga agatgttcga
    14401 gatatcggtg gaatcatgca tagtttcagt ggtgattatg aatgggcaaa acgatttctt
    14461 gacttaggga tgcatatttc atttagcggt gtcgtcactt tcaaaaaagc attagacgtc
    14521 caagaggctg cagcaaatgt accaatcgaa cgattacttg tggaaacaga tgccccttat
    14581 ctggcaccag ttccttttag aggaaagcga aatgaaccag gctatactcg ttatacagta
    14641 gaaaagattg ctgaacttcg gaatcttccg acagaagaag tggctgccca aacatggaca
    14701 aatgcgcacc gattatttgg tctaagcgaa catggataag atgaagatcc aagagattat
    14761 agtcgttgaa ggaaaagacg atacaagaag gctgcgggaa gtagttgatg cagatacgat
    14821 agaaacaata gggtctgcaa tcaatgaaga gatcctgatg caaattgaac atgcccaaga
    14881 gactcgtgga gtgatcgttt ttaccgatcc tgatttttca ggagaaaaaa taagaaaaat
    14941 cattatggaa gctgttcctc aggcaaaaca tgcttttttg ccgcgcacac aagctaaacc
    15001 aaagaaaaag ggaagccttg gtgtcgagca tgcaagtgat gctgctattt tagaagcatt
    15061 gaaaaaggtc gtgacgccag acatttccca aacggctgtt tctgaaatca ctagacaaga
    15121 ccttttagac tatggtttaa tagctggggc acaagcaaaa gaaaaacgag aaaaactagg
    15181 tgacgagttg cgcatcggtt acacgaacgg caaacaattg gaaaaacgtt tgaagatgtt
    15241 tcgtattacg ccgaaagaac tcgcccaagc aatgaaaata gtggaggaac aacatgagtg
    15301 aatatcgtga aattgcgaca ccctctagaa caaaagagat tttattgaaa catggttttt
    15361 catttaaaaa aagtttagga caaaattttc tgactgaacc aaatatttta aggaaaatcg
    15421 tagaaactgc gcaaatagat gaacatacga acgtgatcga agttggacca ggaatcggtg
    15481 cattgacgga acaattagcc aagcatgcaa aacaagtcgt agcatttgag atcgatgatc
    15541 gtttgatccc tgtattggct gatacgatgc aaccctatga caatgtgact attgtacatc
    15601 aagatatttt aaagaccgat ttgtcaacag ctgttagaga aacatttcat gaggagcttc
    15661 cgttaaaagt cgtagcgaat ttaccttact atattacgac accgatcatg atgcattttc
    15721 ttgaatcaga tttggttgtg gatgaactag tcgtcatgat gcaaaaagaa gtagctgatc
    15781 gtatctctgc tgaaccagga acgaaagctt atggttcatt atcgattgct gttcaatatt
    15841 atatggaagc cagtttagca ttcatcgtac caaaaacagt atttgtccct cagccaaatg
    15901 tagattcagc gattttgaaa ctgacaagaa gagatatacc ggcagtcgaa gtgacagacg
    15961 aaaaagcatt tttccgattg acaaaagcgg catttcagca aagaagaaaa acgctttgga
    16021 ataacttgca gcattcgtat ggcaaagatg accagacaaa agcatggtta gcaaaaagct
    16081 tggaaacagc tggaatcgat ccaaaacgtc gtggggagac tttgtcatta caagaattcg
    16141 ccgcattaag caatgcgatg tcagaaaata tgcagtaaaa aaagaggttg tgacagaagt
    16201 tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca aacaaaaata gttcctcatg
    16261 tttttcgttt gtttgggctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    16321 aggttgtggg cctgccgttt aactctaagt cacaaggaac aatttcaaaa aacagcttct
    16381 catgtttttg agttagttgg tcttattact tgatgcaagc ttttgaccac tattatgccg
    16441 aacaaggaga tgtgacacaa attttgtcac atctcctatt tttgtttctt gatcaaaaaa
    16501 ttcttatact tgatactcac actcattttg tatggattta gaaaagaata tgtgtcttga
    16561 cagttattag taagtgagtt atactaagtc gacatttatg tgtcaagaca tattaggaga
    16621 gagaaaaaat gagaaaaaat tcagttcgaa aactaacgat ttctgcttta ttgattggga
    16681 tgggggtcat tatcccaatg gtcatgccta aaatcatgat tccaccagct tcctttactt
    16741 tggcgtctca tgtgccatta tttattgcga tgttttttac accaggagtt gcagtggctg
    16801 ttgcgctagg tacgacattt ggtttctttt taacaacgcc ggttatcatc gcattgcgag
    16861 cattgtcaca tcttgtgttt gcgttgattg gggcttggta cttgcaaaag catccgagta
    16921 tcgttttaaa aaatggacag tttacttttg ctaattggcg tttccaaggg ttcaattttg
    16981 tgatcggtgt gattcattct ttagcagaaa tgctagtagt cagcatcttt tactttattg
    17041 gtaatatgcc tgaaacatat tattctcaag gatattttta tacagtattc atcttgatgg
    17101 ggattggtgg gcttatccac agtttagttg attataatat tgcttatttt atagcaggaa
    17161 cactcagcaa atattttgat atccccgtat ttacggcagc aaaaaaagaa aatcggaaag
    17221 agtcgattca agggtacgcg aagaaaacga catattagac atgatctctc aaaaaaaaaa
    17281 ctctcatcta gtaatggata ataaatcctc taagatgaga gttttttgtc ctaaaaagag
    17341 ctgcaccaac atcttctggc acagctctaa cagggggcaa tttatggaag tttgatgact
    17401 tgttctgttt ctttatcaaa gaagtggcct ttgctgatgt tgaaggcaag gtcgactatt
    17461 tcgcctggtt tatggaaatc tcttgcatct acttttgaga tgaactcagt agaaccagtt
    17521 tttgtgtaaa gcatcgtttc agctccaagt aattcggaaa cgacaacttc tgatttcact
    17581 acggcttcag gtgaagcttc aagggctact tgttcactgt ggatgtcttc tggacgaata
    17641 ccgaagataa cttcttttcc ttcataacct ttttcaacta atactttgtt ttttccttca
    17701 ggaatacgaa gcttaagccc atgtccatct gtgataacac catttttcaa tgtcacatta
    17761 aagaagttca tggcaggaga tccaataaag ccggcaacga acatattgac gggtgtatca
    17821 taaacttctt tcggtgtacc gatttgttgg ataaatccgt ctttcatgat aacgattcgg
    17881 tcagccatag tcattgcttc tgtctgatcg tgagtaacat agatggtcgt tgtttcaaga
    17941 cgctggtgaa gtttggcaat ctcagcacgc atggctacac gtaatttagc atctaaattt
    18001 gataatggct catccattaa gaagactttt gcatcccgaa cgattgcccg tcccaatgcc
    18061 acacgttggc gttgtccacc agataaagca gctggttttc gtttcaagta ttctgtcaga
    18121 cctaagatct ctgctgcatt gtccacacgt tttttgatgt ctgctttatc atatttacgt
    18181 aatttcaagc caaaagccat attatcaaaa acagtcatat gaggatacaa tgcgtagttt
    18241 tggaaaacca tggcaatatc acggtcttta ggtgccacgt cattcatgac ttttccgccg
    18301 atatttagtt ctccttcaga gatatcttcc agtcccgcga tcattcgcaa agtagttgac
    18361 tttccacaac cggaaggacc aacaaaaacg ataaattcac ggtctttgat tgatagatta
    18421 aaatcagtta cagaataatt ttctgcattg tcatattttt tatatacgtt tttcagagcc
    18481 atttctacca taatacgttc cacactttct tttttagttt tattaactat ttaaagtata
    18541 aatgaaagcg ttaactaact tcaatgtcat gttgaacaag aattttttct tttttttgtc
    18601 aatgtgctag ttttaagc
//
LOCUS       DAIGSZ010000059        18401 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.059, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000059 DAIGSZ010000000
VERSION     DAIGSZ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.059"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(405..1019)
                     /locus_tag="NOB31_002133"
     CDS             complement(405..1019)
                     /locus_tag="NOB31_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0974326.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1625..2002)
                     /locus_tag="NOB31_002134"
     CDS             complement(1625..2002)
                     /locus_tag="NOB31_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974327.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2302..3183)
                     /gene="galU"
                     /locus_tag="NOB31_002135"
     CDS             complement(2302..3183)
                     /gene="galU"
                     /locus_tag="NOB31_002135"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCI0974328.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(3226..4245)
                     /locus_tag="NOB31_002136"
     CDS             complement(3226..4245)
                     /locus_tag="NOB31_002136"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCI0974329.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            complement(4878..5882)
                     /locus_tag="NOB31_002137"
     CDS             complement(4878..5882)
                     /locus_tag="NOB31_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0974330.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            complement(5895..6944)
                     /locus_tag="NOB31_002138"
     CDS             complement(5895..6944)
                     /locus_tag="NOB31_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0974331.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            complement(6961..7782)
                     /locus_tag="NOB31_002139"
     CDS             complement(6961..7782)
                     /locus_tag="NOB31_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0974332.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            complement(7769..8548)
                     /locus_tag="NOB31_002140"
     CDS             complement(7769..8548)
                     /locus_tag="NOB31_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0974333.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            complement(8565..9035)
                     /locus_tag="NOB31_002141"
     CDS             complement(8565..9035)
                     /locus_tag="NOB31_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0974334.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            complement(9047..9466)
                     /locus_tag="NOB31_002142"
     CDS             complement(9047..9466)
                     /locus_tag="NOB31_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HCI0974335.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            complement(9547..12324)
                     /locus_tag="NOB31_002143"
     CDS             complement(9547..12324)
                     /locus_tag="NOB31_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0974336.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            12515..12739
                     /locus_tag="NOB31_002144"
     CDS             12515..12739
                     /locus_tag="NOB31_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974337.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            13518..15233
                     /locus_tag="NOB31_002145"
     CDS             13518..15233
                     /locus_tag="NOB31_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974338.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            15236..16999
                     /locus_tag="NOB31_002146"
     CDS             15236..16999
                     /locus_tag="NOB31_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974339.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(17039..17575)
                     /locus_tag="NOB31_002147"
     CDS             complement(17039..17575)
                     /locus_tag="NOB31_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCI0974340.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(17898..18320)
                     /gene="mgsA"
                     /locus_tag="NOB31_002148"
     CDS             complement(17898..18320)
                     /gene="mgsA"
                     /locus_tag="NOB31_002148"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HCI0974341.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
BASE COUNT         5443 a         3785 c         3141 g         6032 t
ORIGIN      
        1 ctgttggaca attttgttat atcaggtaaa cttcattgca ataatgataa caaatgtact
       61 ataattactt tgtaaagagt tttggggaag actctttcat caacgtgtat taagagacaa
      121 gaaagaatcc atatggattc tttcttgtct ctttttccac tactttttat ttttctgaca
      181 ctacatattc ttataactca tttctcataa ctgtgaaaca acttataaaa ataacaaact
      241 ttaaacaaaa caagcttaaa atcaaagatg atccatctta aaataactaa aacaaaaaaa
      301 gtagtcgttg ttaatcctca ttaataatcg ttttcttttt ttcaaacgct ccatttttat
      361 gtggaacatt atttttttaa ggaactttgt caacatgtgg ataactattt tccacttgtg
      421 tcctggacta gctgttttgc tgtaaaatac aaaacttgct gcagcaaaaa gatcgttgca
      481 agagaggctg ttccgcagat cgctggatct agatttggca aagtcaagac tgcatcatgt
      541 aaattggcgt ggttgtccaa aaccaaatca gcaaattcaa ataatcgcaa accactgcta
      601 tgttgcgatt tgatacttcg tgacaaatca aatccagtaa caatgattaa tggatgacca
      661 ttttctttga tccactgagc tagttcgatg attgccgggt ttcttccttc attcgaaaga
      721 agaagaaaaa tgtcttctga tttgacagaa agctgatcaa taattgcctg tcctgcacct
      781 tctagcgttt catagacacc tccggctgga ttttcaatca atatacttgg tacaagatcc
      841 ggggtttgat cccaaaattc aaatgctaca ccacttagtg tgcggctagc atatatctgc
      901 aatctaccac cttgattaat ttgtttcgcg atccaagtgc cagcttgaag catcagcggc
      961 tcttctatcc ttaatttctc ttccaattgg tgataatagt caaaataaca taaactcatt
     1021 tatctctccc gcctagctat acttgacatg aatagaaaca gctgcctaat ctaaggaagt
     1081 acataaaaaa acagtagtta gacagtaaca catgtggtct ttgctgtttc aaacacaaaa
     1141 aaggcattga acgaatacgc ccaatacctt gacatagcaa ataaaacaac gtgcagacca
     1201 tggaaaatat ctacataggg gtagaatttt caccctagat taggtacaat aaattaggtc
     1261 gatgcactgc attgactatg gcaaaatgat cggtcagggt gtatgtgtgt gactggtcat
     1321 tccctgattc ttagcgccaa ctaagggtca gggagccttt ttttattcag ctgtttctat
     1381 ctgaatttat tgtaagtaat ctcttatcca agtgcaagca agaaaataca aaaaaacatt
     1441 ggtatgattt atatatatat aaataacata aaaaaaggaa tggcttatcc cgatacaaca
     1501 agcattcctt taaaaaagat tcttttatat aagtgaaaaa agcttttttc caccaattaa
     1561 ataaatctct catctcaata gtttatccat tattttatct ttttttgcgt atacctacta
     1621 aatattaccg tcttcttctc gttcttctac tttgttcgag agaatctgta ctagaaaaag
     1681 tagttgtatg tctacctttt ctgcctatcc gagactttct tttcatatat gggatataaa
     1741 tgattagata cagtacagca aaaaataaag caaatacgca agcttcccaa ctacctaacg
     1801 ccaattcaac catcaaggta gcaaccccaa cggatgctgc ataccagata aaaatcagaa
     1861 acgtttcttt ttttctgacc atgcgaaaca tgataaatag actaataagc aatagtggca
     1921 acacaaatat ccaattgctt ccttccatca gccacttgag tatatcaagc agcgactgtg
     1981 caacagcgac taattttccc atagtgaaca cacacctttt tttataatta aaaaattcgc
     2041 ctttttattc tactatgaat cttctggctt ggctttcatt tctcttatgt aatcattttc
     2101 ttttatacaa cttaaaaaaa aattaaacca ttagcataat attttctgaa tctattcacg
     2161 aaagtctttt tctatctttc gttttccacg actcaactga tctagagtca aaaaactaaa
     2221 acgacagttg cgcaaatgac gcacaagctg ccgctttaat aacaaatagc ctttcattct
     2281 cagcaggcca cttatttcca gttaactttc tgttcttagc tttttactca actggataat
     2341 atatgcactt aatgaagtcc caatttccga atgttgaagt ccatattcaa tatttgtctt
     2401 catatatcct aacttatcgc ctacgtcgta tctttttcct ttaaactctc tcgcatagac
     2461 cgcctctgtc tggttaagag tctgaagtgc atccgttagc tgtatctcgt ttcctgctcc
     2521 tggttcttga gtttctaata tctcaaatat tttaggagtc agtagataac gtccgataat
     2581 ggctaaatta cttggtgctt ttcccatttc aggtttttct acaaaccctt ttactctgca
     2641 acgacccttt tcgctatctg ttttaggatc aataattccg tatttagatg tttcattttc
     2701 tggtacacgc atgacggcaa cagcggaagc ttgtgtttct tcataatcca tcatcaattg
     2761 ttgagtcaat gggatatcat ctttcatcaa atcatccccc agcatgacga caaacggttc
     2821 atttcctata aatgcttttg cttgaagcac ggcatccccc agtcctcttg gatgagattg
     2881 acggatgaag tgaagattga cttgagtcgt ttcttcaact aaagcgagta attctgtttt
     2941 ttccttttcc cgcaaattgt tttccaattc gatatttgca tcaaagtgat cttcaatggg
     3001 tcttttttct tttcccgtta cgatcaagat gtcttcgatt cccgaatcca atgcttcttc
     3061 cacaataaac tggatcgttg gtttatccac gattggaagc atttcttttg ccatggcttt
     3121 tgttgccggc aaaaaacgtg ttcctagccc agcggcagga atgactgctt ttttgacctt
     3181 cacttgctgt tcctcctaaa cgacgattaa ctattgatca tctatttaac gaagagaaaa
     3241 ttcattctcc atttttccgt cacgtaacat gatttctttt gctgcttttt tgatatcttc
     3301 tccattatac aaaacattat agattgtttg agtaattggc atctcaacac ctagctgttg
     3361 agctagctct actgctgctt ttgtcgttgc cacaccctca acgaccattc ccatgttttc
     3421 tagaacttct tccagcttat gtccctgtcc taacaagtta ccggcacgcc aattgcgaga
     3481 atgaacactt gtacaagtaa cgatcaagtc ccccacacca ctcaaaccga taaatgtcag
     3541 aggattggca cccatcgcga caccaagacg gctgatttct gccaatcctc gagtcatgat
     3601 tgctgctttt gcatcatctc cgaatcctaa tccatggata gcgccggcac caattgcaat
     3661 gatatttttc agtgctgcac cagtttctac gccaatcaca tcattatttg tataaatcct
     3721 gaaataatca ttcatgaaca gtttttgtac ataggctgct gctttttgat caatacttgc
     3781 agctgtaatt gttgtgatat catgtactgc cacttcctca gcatggctag gaccagataa
     3841 tacaacaatt gcctgtcttt tttcttctgg aatttcttca gccaaaactt ctgagattcg
     3901 tttatgcgta tcttgttcta gtcctttact tgcatgtata atgattggct tagtattcat
     3961 tttaccaata agttcctgtg cgactgaacg aatcgctttt gttggaacaa caaataaaat
     4021 agcatctgcg ttatccactg cttctgccaa ttctttatat ccgataatcg attctgggat
     4081 cgtcaaatca ggtaaaaaat gctgatttgt atgatactta ttgatttcat caatctgttc
     4141 aggtacattt ccccaaatac ggacatcatg cccgttttct gccaatgttt gtgctaaagc
     4201 agtgccccaa gatccaggac caagaactgc gattttttgt ttcatggata ttcctccaaa
     4261 taaataattg ataatttcca ttatagtata catttcttaa agttgggact aatttccatt
     4321 gtttttaagt gtttgtttac ttcttttatc gtttttactt gaaataatca atgatatgtt
     4381 acaatagtct acattttatt tttacactcg ttatgctttg cttgttccta agaggaagca
     4441 gttttgacaa tgttactacc agcattacta ttaggaggtt aggaaacttc tcctagtgag
     4501 tattgattta aaatacataa gagacagatt gaacatttct aaatctgtca ggtcctgcaa
     4561 cggacagatt gtctctgttg acggttgaca taggaacttt tgttttagtc aacattctgg
     4621 atacaaaacg ctatgtaaac tggcgcaact cgttgtactt ggacttttac tacggatcca
     4681 tgcaacaact aaatagtact attgcataac aaaaaatggt tggcacccac atgtcccatt
     4741 aaacagatta taagttgaac tgtagataat gcaaaaaatg tgttttataa cgtaattgat
     4801 gccaatattt taaaaaaata aagggagcag ttatcgctgc tctctttatt ttttatattc
     4861 tttttatcca gtctatccta ataatcaaac tgacgatagt agcggcgtat ctctaatgga
     4921 tggcagttca actgctccac atgagcatcg atgcgttgtg tcactacatg catcaataag
     4981 aaagacaaaa cacgtccgcg atatttttca ctgatacctt ctactggata gtcttttgtg
     5041 tctatcaatg tataattgct gcaaattttt ggcaaaagtt tagccacacg ttcagataac
     5101 actctctgtt catcttcgcc taaaaataat gtgactgggg ttgtttcttc tacgatctct
     5161 aacgtcccgt gaagaaactc ggcagcatgg atagatttcg atggaagcca gctttgttct
     5221 tcccagtaac acatggcata tgaataaaca gctccccatt gattccctgc tccaataaaa
     5281 taatgcatac tatcacgtcg atgtttttct gcaaatgata agccaaatgc atctgctttt
     5341 ttctctgctt ccactaaccc tgttggtaaa taacgttcga gctgttcata gtattctgaa
     5401 taagcttcga attctccatt caaatacatc aatcgatctg ctgccataaa aaatttgatt
     5461 tgttctgttc caggagctgg ataagtgacc acaaaatcgc atagctgaga caacttactg
     5521 ttcgctttat cgataaatcc aatcagtgtc gctcctactt tcttgatttg ttctactgct
     5581 ttcactactt cttgagttgt accggtaaca gaggacaaaa taacgataga atcttttgtt
     5641 aatcttttgt ttccagtagt gtaatattct gcagcatgct gtacaaagac aggcaagttg
     5701 cttttcccat tcatataagt gacagcttgc atcgaggaag catacgttcc accgattcct
     5761 agataataga cagcgtcaaa tttttccgca taaagtttat cgatgatttc ttctacttgc
     5821 ggacgtaaag ctagtgcgcc ttttattgct ttgatttgtt cttcttcatt gaatttcagc
     5881 atgatttcca cctcttataa tttacttttc aagactgtat caaagtcttc aaaaatcttt
     5941 ttgttcaagt caataccttt agctactgcg gttttataag cgaatagttg aaacggaacg
     6001 acaagcgcta atacagacag atattcatca cattctattg ctaatccaag tgttttctcg
     6061 tttcttgctt tttttgtggt aatggtgaga gtctctccaa cgtaccgact catatatctt
     6121 tgcaactttt gcgaacgttc cttatttaca ctttcccctt caataaagaa tagcaaatgc
     6181 gaagcatctg cctccaggta tgggccgtgc atataagctt ctaactcaaa tccttgtgac
     6241 ggaacgcgga ttgtttcagt caatttcgtc tctgcttctt tagctgttcc ccagtttgga
     6301 ccatatccaa tggtgacgaa acgctgtgct aaacgaaata aactttgata tccatcaaaa
     6361 aattcttccg ttttttgaat aatcgctggt aaatggttga ttattttgcg caactgttgc
     6421 atgtagtctt gttctatttt tttgctgatt ttatttttac ttattccaat tcctatccct
     6481 aagagtagta actgtaaaac agtcgcagaa tagccttttg taacgaagcc tactgattct
     6541 accccggcac ctaaatcaat aatttgtgca gcttctaaag caagtggact ttgcacgtca
     6601 tttgtgatag caacaacagg taacccttgt ttttgtatca tttttactgc ttcaacagta
     6661 gaagcacttt tcccgctttg tgacacagca atcacagtat cgattgaagg agaaagtttt
     6721 ccataattga aaaaataaaa aggttcttga atatcgacag taagatcacc ataagattcc
     6781 aatgctggct tcgctgctaa acaagcgtta taagatgaac ccgttgctaa gatcagtaaa
     6841 ttcactgttt ttttcatatg ttctcttgtc gaaaaatcat tctttttcaa gatcgtactt
     6901 agtacttcct tttcttcata gatataatct tgcatcgtaa acattttctc tgctcctttt
     6961 ttaaaaaatc cctatccacg aaccaaaaat tccaaagaaa gctagtccga tcaagatcgt
     7021 taatggtttc acttctttct tcaatagata aaacactatg ccaaatgctc caagacataa
     7081 gatatttgga acgatatcat caaaaatact ttgaacagtc acagcatttt ctcctgaacc
     7141 gatttttaaa ggaatattga tggtgatcat cgtggcagtc attgctccaa cgaccatcag
     7201 tccaataata gacgcgccta atgtcaaact ttccatcata ccgtttgcct ggatcttttt
     7261 caaaaaaccc gttcctaagc gatatcccca acctgttgct agatagcgaa acagaatgtg
     7321 cggaatattg aaaatcaaaa tgaacaagat agggcctaaa atatttcctt gcatggctaa
     7381 agaggtaccc acacctgtgg caatcaatcg caaagttccc caaaagaaag aatctcctaa
     7441 ccctgcaaga ggtcccatca aagatgtttt gatactatcg atcgcagtca catcaaattc
     7501 aggatcatcc ttattttctt cctccattgc agccgtgatt cctaaaatca gtgtaacgat
     7561 atgtggggtc gtgttaaaaa actctagatg ccgtttcaaa gctgctgcca tttcttcttt
     7621 cgactgatat aactttttca aaatcggaat cattgcataa acataagcca tattcatctg
     7681 acgttcataa ttccaagaaa actccatttg aaaagaacgc caaaatacgt gatttagctc
     7741 ttttttcgtt attttgctgt ttttgatctc agaattcttc atcttcttct acctcccctg
     7801 cagttgtttg aagtggtagt tgacggacat tcataatatt gactaccaca actgctaaaa
     7861 tcgcaccaaa aatagctact ccggtcacag gaatctctaa gtaagaagct atagcaaaac
     7921 ctaagaaaaa atatggtgca acttgtttgt tgatcagcaa acgagcaagc atcgcaaaac
     7981 caagagctgg aatcaaccct gtagctactg acaacccctt ttgaacgaag tcaggaatca
     8041 tatttaatag atttccgatc gtattgcttc ccaccatata agaaaccatt accacaacac
     8101 caagcatcaa ggaaagaccg ataccggcaa gcaagtgcat atgctcgact cctttataat
     8161 ttccttcttc tgcataattg tctgctttat ggttcataat tggaatcaaa agccctaagt
     8221 aaatattttt caatatcaat gtcaacgtag caatcggcaa acctagtaaa agcgcggttt
     8281 ctgtaccggc tccagctgta atagcaaaag ccgtccctaa aatcccaccg gtcacaacat
     8341 caggtggaat cgaagcacct actgagaacg atccgataaa tgctaactct aaagttgcgc
     8401 ccataatgat cccagttttt acatcaccta acacgattcc tgtaaacagc cccgtcacaa
     8461 tcggacgaga aagcaacgat gtccctagtg catattctga ttgtgcgaca aatgcaacaa
     8521 ttcctaataa gactgcttgt acaatcattg aggttcttcc tttcttacaa aacttctctt
     8581 acatccactt ttttatctgc tggtacttga cggatttcta cttctatttg tttgtcaatt
     8641 aatcgtttca agcgttcctc ctcttctggt aaaatattta ccgcttttcc gatgctgcga
     8701 gtaccaggtt ttgccttgat ccctcctaag ttgatggttt tgatttctgg atacgcttct
     8761 gccagcttat atgcatcctc gatcgattcc actacgatga ataacttata tttatctgtc
     8821 accccgcttt tcaacgcggc aatcgagtca tcaattgatt tgatcactag tttgactcct
     8881 tgtggcttgg ctaatttgat cgttgtcttt cgtatctcat tcgtaggtac atcatcatta
     8941 gcaatcaaaa tacagtctgc gcctattgtt tgtgtccatg aaaaagctac ttgtccgtgt
     9001 aataaccgat ggtcgactct tgtcaataca atcatttttc ttcctcctaa aattcgtctt
     9061 cttctatttt ctgattgagc cgctcgttac aaaactggat catttttttt gaatcagtta
     9121 gcacctgctg gatcaaaaca gttgtctcta cttcagcgtc caaccgagat actagctcaa
     9181 tcaatagtgg caaattcaat ccggcaacga gatagacatg atcccgattg atatattgta
     9241 agaattcgtt gttgacactt ccgccaaaaa gatccgtcag aacaatgatt tctttatctt
     9301 tgtacctcat aaaaagctgc cttactgttt ccgctaaatc aaaattctca tcagtatagc
     9361 aatcgaatac agtaatagaa tgatttttcc catagatcag ctctaatgaa tctaatatcc
     9421 ctgaagcaaa ttttccatgg gaagctaaga taatttctct atccactttt tcatctcctc
     9481 ttttcactta cacatactaa aaaagcaagt tgcatgccaa aattagtggc aacaacttgc
     9541 ttatgttcaa aattcttctt ctatcgagag aaactctgta tcttcactca aaatatcata
     9601 gatataggca atctcagaat tggggatcat gacactataa tgctcttcaa tgacactaaa
     9661 cgcagattta atagcagata acccttcttt ttgacactgc ttccatttct ctaatccttg
     9721 ataggtttcg attggcattt gtcggatcaa tcgttcaatg agacagctca catggacata
     9781 caacgctaat tttttgggat tgctgatgct tcgattcaac tgcacctcta attctctcat
     9841 aaaatgatcg atttctccca tcaccttctc tgtatctaga atagtcacgg aatccagtac
     9901 tttttccaat gaaaaattac gaatgatgcg ctgattgaat atttccttct ctgaagcatt
     9961 catagtagtg tccaaccatt cagctagtac agacatcttt tcccccgaga tgaggtcttc
    10021 taatgaaaga tagtcgatat tggtgatatc aggatctgtg gtgccaatca ttcctacgac
    10081 ttcgtatatg gaaaataatg ggtcactgtt tttcttatct tttaattgct gatattcata
    10141 tgggatgatt ttcaactgac aagccgtagg taagcttttt tctagcagtt cacttaagtg
    10201 gaccgccgta ccgattccag tgaagcaagt agtaatgagt gctttgggtt tgttttcctc
    10261 tggatagagc agtcgccatt ctggctggat ctgtcgaaca gtctcttctg ctatctcttc
    10321 taatgataca tttttttgca ggcattcccc tactgtgatt gctaaaggtg tcgtcacatt
    10381 attcaaaatc aaaagcggta cggataactg ttttttaaaa aactgatgga tttctttcag
    10441 agatcccatg tctactaata tgatcaatcc atttgaaaca tcgctgtttt cgcaataatc
    10501 aaggatttct gaagcaatct gctgtggtgt gacatctagt ggcatatcaa atgattcaaa
    10561 tagatcctct tgtaataaac gatttactac atttgccata ctgctagcag ttgcataacc
    10621 gtgagcagca atcatcgctt ttggcagtcg tttttctttt gaccatttcg ctttttttag
    10681 atagatcgtc agtaaaatcc gatccatact tgtgtcttca atatctaatt tgatcttact
    10741 taattccaga attcgttgga catagtgata actagatgga taagactgag aaacttgttg
    10801 ttctaattct ttgattagtt ggataatatc atgttcttcc ggtaaccatt tgatagtgct
    10861 tcgctgatag agatagtaac tcaaggcata gacactgttt ccatcgaatt tgatttgata
    10921 ggcagtttcc atttgtcgaa aggtctctcg gatagattgt gtccaataaa ccagcagctc
    10981 gtgtttttct tgtctactgg tctcaaacag caaaaaatca aataattgaa tcacttcttg
    11041 ctttaatttt ccttcgcaag aatatagcag acagttattt ttcttgaaat caattaggat
    11101 ttgctcaaaa cttttaacga ttcgctgctg ttcgggctgt tgcttctcca ttaattgctc
    11161 taaggtctgg tcttgcgtaa tatagattcc ttgctgtgct gtatttttag taataggctg
    11221 cgcaagtagt tctttttgca aatgatggat cgtgacatgg atttcaggct gttcacgctg
    11281 ttcagcatat gcttttgctg ctgaaacttt gacgatattt ttcagctctc ctatgtttcc
    11341 ggataatttc tgacttgtta aaagtgacaa agctggtcca ctgactgaca aagggctccc
    11401 catttttctt tgttcttcga gaaaaaaaga gtaaatcagt tctagccgtt cattacgact
    11461 acgctgatta agtgcaggta gttcgattcg gataggtatt cttcgaatga aagttgttaa
    11521 gaaatgacta gtaatctctt cagtcgtagc aaaaaagaga cgtgttttga tccggcgtga
    11581 caaattaggt tctcccatac gataaatcac accttgatca agataggtga acagtttttc
    11641 ctgaccttct ggtgttaagc gatgtacctc gtctaaaaac aagatcccac catctgctgc
    11701 ttcaaaagcc ccttttttat tttcttctgc accagtgtac gctcccttaa catgtccaaa
    11761 caaattgcta gtcaaaagtt caggattatc tgcatattgt gcacaattaa aagtgatgaa
    11821 tggtgcagaa tcttctagca gatcatgaag cagacaatac tgatagacca aattaactaa
    11881 ataactttta cctgtgccac tttcgcctgt aatcaaaagt ggtaatccgc catctggata
    11941 gtaaagagct gttttgattt gttcgatact ttctttcaaa ctggcgtcgt atccgatcat
    12001 aaaagagaat aagtcttttg gttgcgcgaa aaaaggctgt tcctctttga gatcatcgat
    12061 agaaaaataa aaattcgtgc gtaacttaaa aaattgtttt tcaaaagctt ctttgtggaa
    12121 ataaatcact ggtcgagaat tgattttgac tagtagttgc tcatcattta actggttcaa
    12181 ataatgactg actgtgtttc tttttacccc aaaatgatca gctaaccttt gtgctgtaaa
    12241 gacctcgttc atatgttcta aatcgaaaaa ggctgtctgg ttctctaagt aacataaaat
    12301 ttccttcttc aacaacttat tcacccctcc tccatcatag aaaacggatt cattttgtca
    12361 ataaaatctt taataaagaa ttgaaaaata tatcttatta tagacagcag cctacttatc
    12421 ccttataatt tttattctaa aaaacgtaca gttccttcca gtttttatac tggaatttca
    12481 acatatgaaa gaataaggag gctatgacta ttcaatgaaa tcggataaat ataaaaacag
    12541 gaaacatact tcctggaaaa cttttcgaga aatcatcgga tcttatctcg ctgtagttgt
    12601 atttttgcct ttgctttata tggctatgac agaacaaact cgttttattg gcgtagatac
    12661 gcaatatata gccgaaacag gatttttatt catctttatc ttgatttttg cgttctataa
    12721 atccttccat acaaaataag attcacagat ttcaactttc ctgtctgttt ttagctatta
    12781 caaatcctta tatgtggtat aacaacaatt tattggcata atgaggaaaa acgagttatg
    12841 atgctttcag agagtaaaga ggtactgttg tcaccatcct ttttattgat tacgtacacc
    12901 actcttagtt ttttcccatt gattacgaaa acaaggtaga aacattgatg ttcctacctt
    12961 gttttctttt tttattttca gatcaaaatc tcaagtggct tttgacttga tgtcgggagg
    13021 ttgtcttcgt tccatcaaac ctgatagaat ctgcgccaaa ccatagtttt ctccactatt
    13081 atttattcct ctaagatagt acccacaata aacgaataaa tatttttctc attttcatac
    13141 tccttctttg aaaatcaatt agatttctct caacccactt ttttacaaaa attacgtagc
    13201 aaaaaagatt gcaagaacaa attaaaaaag aagtaaatag agtttcatct ataaacattt
    13261 acttgatata ttttttatgc agaattcatt tatagaaaaa ttaagtaaaa tagacgttcc
    13321 tatgaatgaa gagactggca tgttttctca ttttcttttt tttaaaaaaa atagtctatt
    13381 caatttctaa agcttcttca taataaaact ttcatttatg aaaaggcttg ttctcttttc
    13441 attctaaatt tcctaagcta caatgtggta gtacttgttt tttcaattgt ggacaaataa
    13501 ataataggag gaatcatatg attcagttat tacgttatgc aaaagactat cgtaagcaaa
    13561 tcattttggg cccgttcttc aaatttcttg aagctgtctt cgaacttgtc ctgcctttaa
    13621 tgatggcttc cttgatcgat aatggactaa aaatgaatga ccgaggaaaa atcattgaaa
    13681 tgggcttatg gatggtcgct atgtctgtga ttggtctgat ttgtgctatc atttgccaat
    13741 actatgcttc agtagcttca caaggatttg gtacagagtt acgtaatcag ctaatcaaaa
    13801 aaatcaatac tttctctcac aacgagttga atcattttgg aacagatacc ttgatcaccc
    13861 gaatgacaaa cgacatcaat cagcttcagc tagctttagc aatggtcatt cgtttattga
    13921 tcagagcacc gtttttaagt atcgggtcag tggtcatggc ttttgtgatc gactgggaag
    13981 taggtctgtt tttcttagca ttattgccta ttttctcaat cattttattt tttatcatca
    14041 aaaaaaccgt tcctctctac caaaaagtgc aagaaaaact agatcagctc aatgaacacg
    14101 ttagtcagaa tcttagcggt gttcgtgtca tccgcgcatt tgcgcagaca aaaaaagaaa
    14161 cagagaagtt cgataaaagc acaaatgatc tagcgaacaa ttatttacgt gtttccaata
    14221 tctctgccct attatcacct gctacaacct tgatcatgaa tgtcgggatc atctgtttgc
    14281 tgacagttgg cgggatcaaa gtaaatattg gtagcttgca acaaggacaa gttcttgctt
    14341 tgatcaatta tatgaatcaa atgcttttgg cactgatcgt tgtttcaaac ctcgtcgtga
    14401 tcttcacacg tgccgaagct tcaggaaatc gggtgaaaga ggtgctagac acagaaaatt
    14461 cgattcttga agctgaggtc agtactactc ccgatttttc ttctgaagca attatcgctt
    14521 ttgaccatgt tgacttccgt tatactcctg attctggtct ttctctccaa aatattacat
    14581 ttcagctgaa gcgaaataca gtccttggaa tcattggtcc aaccggaagc gggaaaacga
    14641 ctttgacaca attgattccg cgtttctatg atgtcagttc cggtacagtt ataatggacg
    14701 gaatggatgt tcgttcttgg cagctggatc atctccgtca gcaaattgct cttgttcccc
    14761 aaacttctgt actatttacc gggactattc gtgaaaacct tcaatggggt aagaaagacg
    14821 ccacagaaaa agaatgttgg gaagctctga aaatcgctca ggcagaagaa tttgtccgtc
    14881 agcttccaaa tggtttagat acaaaagtca tggaaaatgg gaaaaatttc tctggcggac
    14941 aaaaacagcg actgacgatt gcaagagctt tgattgccaa gccagcatta ctgattttag
    15001 atgactcttt aagtgcgttg gattatcaaa cagacttgga tttgcgtaag gcgctacaga
    15061 cttatcttgg cagtacagtg attattatct cccaacgtgt ccgctctatt caagaagcac
    15121 atcatatctt agtgatggat caaggtaaga ttgctgctca gggtacccat gaagaattac
    15181 ttgctcaatc agcagaatat caggaaatcg tcgcatcaca ggaggaagaa tagttatgaa
    15241 agtaaaaaaa ttatccttgc agacgctccg ccgattcatt ccttacctta ctgcctatgc
    15301 aaaagacatt tggctagctg tgatactagg aatcatcaat gggattgcaa cagttgtgat
    15361 gacgttacaa attggtcaaa gtatcgatca aatgattgga gaaggacagg tccgcttcaa
    15421 tcgactgttc catttactta ttctattcgg tggtatcgtt ttaatcaacg tagtcagtca
    15481 atggctcatc caagtgttaa gcaatcggtt agcttactta tccgttgcaa aattaagaaa
    15541 agatgcattt gctcatctga atcgattgcc acttcgttat tatgatcaaa actcccacgg
    15601 aaatatcgtc agtcgattta caaatgatat ggacaatatt tccattgcaa tttctgcggc
    15661 cttcaatcaa ttattttctg gagtggcaat catcattctt tcgtttattt ttatgatgcg
    15721 tctaagtcca cttctgacat tggtcgttct ttgttctaca ccaattattt tccttgtgag
    15781 ttggatcgtt gctcgtgctt cacaaacaaa tttcgataga cagcaaagga ttattgggga
    15841 tatctcgggc tttgtgaccg aacgaatcgg taaccagaaa atcgtgaaag cttttcagca
    15901 agaagaagct agtcaacagc aatttgaact gctaaatgct gatctatatg aaaaaggaca
    15961 acgggcacaa ttttcttctt ccttgacaaa cccgtcttct cgttttgtag atcaccttgc
    16021 ttatttatcg attggtttag ttggcggcct attggcattg aagagtggtt cgtcaatcac
    16081 tgttggtgtg atttccagct ttacgatcta ctcaagtcag ttttctaaac catttatcga
    16141 actttctgga atcacgacac aactgcaaac cgctttttct ggtctagaac gagcatttga
    16201 tttgatcgat cagccagaag aaaagcctga tttgccagat gcctatgcct tggaacccaa
    16261 aaatatcaaa ggaaaagtct cttttgatca tgtttctttt tcttatgacc ccaagcagcg
    16321 tttgatcgaa gatttcaatt ttactgctta tccaggtcaa accattgcta tagtaggaaa
    16381 aacaggggcc ggaaaatcca cacttgttaa tttgctgatg cgtttttatg acacaacaaa
    16441 aggaacaatt acagtcgatg accatgacat ccgctctatc caacgtgata cattacgtaa
    16501 aagttttgga atggtgttac aagatacttg gctatttgac agtacattgc gagaaaatct
    16561 tcgttttggg aatccggaag caagtgacgc agaaatcaat gatgccctaa aagcctctta
    16621 tatgtatgaa tttgtagaac gtttgccgga aaaattagat actaagattg gcggtcaagg
    16681 gttaaagata tcagatggac aacgccaact gttgacgatt gctcgaacga tgatcagtaa
    16741 tccccctatg ttgatcttag atgaagctac cagctcagtc gatacattga cagagaaaaa
    16801 aatccaacaa gccttcttag caatgatgga aggaaaaacc agttttgtga ttgcccatcg
    16861 cctgtccaca atcaaaaatg cggaccagat attagtgatg gatcagggag ctattgtcga
    16921 aatgggcacc catgatgagc tgcttcaaaa agatggttat taccgacggc tctatcaagc
    16981 acaattcaca gcacaataaa aacaagcagt cttctgggat gggaagactg cttgtttttt
    17041 atttagcgtg gatcgctaaa cttcttaaaa tttttttgta aggaatacta cgtcctacgt
    17101 aataaatggc aattgattga atcggtaacc atattactgt ttttaacagg cggggcgccc
    17161 aaacgaccca gctgaacaat ggcacatggt acatcaacgc aagccataat ggtgtcaaaa
    17221 ataagttgat gatcagcgtg acactaagcg tagccagaat ggcatttttc caagtgatct
    17281 cttttcgata gaaaaagaat ccgtagattg ctccttcaat aaatgcattc aatgtaaatc
    17341 caataaagaa tgcagatttc gagaagaggg ccattcctac taaatcagct aaaactgcgc
    17401 ctatccctga ccaaaaagga ccaaaaagaa tgcccatgat cacttgtgga ataaatgtga
    17461 cactgatttt aataaatggg gtctcgattg ctaccagtcg ggacaaagtg accatcaatg
    17521 caatcaataa gcccataata gcaatcatac gtgcgtctaa ccggtgtttc ttcattttta
    17581 gcatctcctt taagagctgc tacatcgtat catgcagcga atgcgaaaat aaaaccgcga
    17641 acattacgtc cttcgtccaa gaggcaacat cccatcctct tagcacttaa cgctttattt
    17701 tctactctgt attatttttg ggatcttttc ccacagaaac tatagcatat tttcacattt
    17761 actgcaaata cgaaaaacta atattattgt ttatattatc caatacgttc gtattatatc
    17821 gcatattatc agtttgttta gcttttatag ctacatatag gcgaacatta aacgttattt
    17881 ttccatacgc ttatccatca aaatgaaagt ggatgcttgt ctatttcatg gacgattctt
    17941 cgaaaatcta ggaagccggc ttccagtcct cttagtagca cctcagctgt tccgatattc
    18001 gtagctaacg gaatctcata gacatcagat aaacggataa gtgctgttac atctggttca
    18061 tggggctgtg cagccagcgg gtctcgaaga aaaatcacca aatctaactg atcctccgaa
    18121 atcatggctc caatttgctg atccccgcct aacggtccgg atttaaaccg atggatcggc
    18181 aagccggttg cttccgtgat cctctgccca gtcgtcccgg tagcaaaaag ttcatgtttt
    18241 tccaatattg ttttatacgc tgttgctaat ttcaccatca taggtttttt tcggtcatga
    18301 gcgatcaaag cgattttcat aagagacact ccttttgata ttgttaacat acttatttac
    18361 tccagtgtat cagtttttat ttcttatgga tatttattaa a
//
LOCUS       DAIGSZ010000060        17746 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.060, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000060 DAIGSZ010000000
VERSION     DAIGSZ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.060"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            201..1166
                     /locus_tag="NOB31_002149"
     CDS             201..1166
                     /locus_tag="NOB31_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCI0974342.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(1265..2437)
                     /locus_tag="NOB31_002150"
     CDS             complement(1265..2437)
                     /locus_tag="NOB31_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0974343.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(2424..3569)
                     /locus_tag="NOB31_002151"
     CDS             complement(2424..3569)
                     /locus_tag="NOB31_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0974344.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(3583..4515)
                     /locus_tag="NOB31_002152"
     CDS             complement(3583..4515)
                     /locus_tag="NOB31_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974345.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            4632..5711
                     /locus_tag="NOB31_002153"
     CDS             4632..5711
                     /locus_tag="NOB31_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI0974346.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            5708..6326
                     /locus_tag="NOB31_002154"
                     /pseudo
     CDS             5708..6326
                     /locus_tag="NOB31_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(6436..6663)
                     /locus_tag="NOB31_002155"
     CDS             complement(6436..6663)
                     /locus_tag="NOB31_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCI0974347.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(6766..9354)
                     /locus_tag="NOB31_002156"
     CDS             complement(6766..9354)
                     /locus_tag="NOB31_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HCI0974348.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(9374..10033)
                     /locus_tag="NOB31_002157"
     CDS             complement(9374..10033)
                     /locus_tag="NOB31_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI0974349.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(10082..10585)
                     /gene="trmL"
                     /locus_tag="NOB31_002158"
     CDS             complement(10082..10585)
                     /gene="trmL"
                     /locus_tag="NOB31_002158"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HCI0974350.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(10806..11672)
                     /locus_tag="NOB31_002159"
     CDS             complement(10806..11672)
                     /locus_tag="NOB31_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCI0974351.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            11781..12422
                     /locus_tag="NOB31_002160"
     CDS             11781..12422
                     /locus_tag="NOB31_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HCI0974352.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(12484..13845)
                     /gene="mgtE"
                     /locus_tag="NOB31_002161"
     CDS             complement(12484..13845)
                     /gene="mgtE"
                     /locus_tag="NOB31_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HCI0974353.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(13863..14762)
                     /locus_tag="NOB31_002162"
     CDS             complement(13863..14762)
                     /locus_tag="NOB31_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCI0974354.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(14764..15561)
                     /locus_tag="NOB31_002163"
     CDS             complement(14764..15561)
                     /locus_tag="NOB31_002163"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HCI0974355.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(15539..16243)
                     /locus_tag="NOB31_002164"
     CDS             complement(15539..16243)
                     /locus_tag="NOB31_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HCI0974356.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            16374..16949
                     /locus_tag="NOB31_002165"
     CDS             16374..16949
                     /locus_tag="NOB31_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HCI0974357.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            17067..17744
                     /locus_tag="NOB31_002166"
     CDS             17067..17744
                     /locus_tag="NOB31_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCI0974358.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         5250 a         3806 c         3152 g         5538 t
ORIGIN      
        1 ttttttgtgt ttttcggtct tcggaccttt ttcattttcc tagacttctg ctataataac
       61 caagaattaa ttttgtaaca gatttttttg aaaaaacaag tttctttcat tcaaaaaata
      121 gaaaaagctt gctaattatt ggttaaccag caaacaggag tattaaaata tcttgtttta
      181 ttgaatagca ggaggaaatc atgaaattcc attatcatat attgatcaat ccatcggcag
      241 gcagcggaaa tggctataaa gtagcagaaa gaattttacc ggtattaaaa aataagcata
      301 ttgactatac acttcattat agtgaataca aaggacacga tgctgagatt gctgaaactt
      361 tggcaaaaga aacattgatt ccttggatag aagaagaaca gaaaacaatc gatactttcc
      421 cccttttgat catcgtagga ggtgacggca ccttacatca ggtacttgat actttctatc
      481 agatggaagt agaattccca gttgcttata ttccagcagg ttctggaaat gattttgctc
      541 gaggggcagg ccttccaaaa aatcccaaaa aaggacttca gctgatttta gcagctcaat
      601 caccagaaaa agtccacata atggcttatg aagaaaaaat aagtgaaaaa aaaggaatag
      661 ctgttaataa tttcggtata ggattagatg cagctatcgt ccatgcgaca aatcattctt
      721 ccacaaaaaa gcgattgaac aaatacaact taggatcatt ttcgtattta ttctctattc
      781 tccgtgcttt attcactcaa aaaggatttc caattctggt agatgcagga ggaaaacaat
      841 taagtttttc aaacgcattt ttatgtacag caacgaagca tccttttttt ggcggaggaa
      901 tcgcgattgt tccaactgct gatgcgtcta aaccagtcat tgattttgtc gtggtcgaac
      961 gaatcaattt ctttaaaatc ttgtggctca ttcttttact tatacagaaa aaacaattga
     1021 aatcgaaata tttccatcac tacacaacaa acagattacg tatcgtttca acaacaccgc
     1081 aacatggtca agaagatgga gaagaaatgg aaaaacgacc ttttgatatc acaataacca
     1141 caactaaaca gttgttttgg tgttaataaa agaggttttg tcagaagcta catctggaac
     1201 accgtttatt cggaaaaaag gactgtgaca cgacttttgt cacagtcctt tttttactat
     1261 gcagttaatt ctttgcccaa ttgggttgcc atcgatagtt tctttcttta cccaaaataa
     1321 attggatcat tgaaaacacc gcagcaaaag caactaagac acaaccattg aaccaaaaag
     1381 attctgcaaa tgtttgattg taactgagtg tttcactgat caagttatta ttttgaacaa
     1441 accaatatgt tggtgtgaat gccgctattt tgctaaccat ttctggcaag tattctgctg
     1501 gtacaaacac cccaccgata aagcaactgc ctgtgataaa aatatctttg atcccaccgc
     1561 tggtttctga gttttttacc aatgaagtga tacaagccga aaagctaatg atcggcaata
     1621 aaaacaagaa agtatttaaa atatgatacc ataccgttat atcccacgag gtgtggatca
     1681 ctaacagaac cattagaagt aagaagccac tgaacaacag cagcgagtaa ctaatcaaac
     1741 taaaggttac tttgcgattc aagtttcgtt tggtaatggg cgcactctgg tttcgtttac
     1801 tgatctcttt gcgattaaac gctagattga tgacgctgaa accgctaaaa atggatagaa
     1861 acaacccata agacaagaaa ttaaaggttg tgcccgtcaa cagctttttc atccgctgac
     1921 tatatcccgc acttagctca acttctccag taaccgagag tgccatttgt gtctgttcca
     1981 tagctgcatc gattgtttta tcttcttctt gaaacagaat cagtgtttgc aaaaaggtgt
     2041 tcacttgctg tgtaacaact gttttagaaa aggcatctgg gcgactctgt atcttgatcg
     2101 tcgccatctt tcctacttcg acttgttcgg taaagtctgc aggcagatgt aagataatgt
     2161 ttacacgatt aaaataaaga gcatcatcga tttctttttg tgaggttcca tccaatgtaa
     2221 cgactgtttc cttgtcattc aaatatttac gaaggccatc gactacaggc gactcttctt
     2281 cactaatcaa ggcgattttc gcatcttgca gagaggtatt ttcaacatca atattttgcg
     2341 caaaaaagaa tgtggcaaca acagtgataa ttacacctat cagtaaattc gatttatttg
     2401 ctttaagcaa tgtccaaatc gttttataaa gcgtcataac gcacccctct ttccatccaa
     2461 gcatttccta acgcaaaaag gaaaataaat ccgatcaacc atagaagatt ggtataaaaa
     2521 ctagccaaat cagtgtagaa ataaagttta tacaaacttt cgctgatcaa gttgacgaga
     2581 tttaattgac caacaatcgg aatatgaaga tcaatccaat acttcacttg ttccgacccc
     2641 atcataccag caaaaaagct catcgcaatc gtcactgaaa tcaagatgct atccttttgc
     2701 accagattca tttttggtat caaattacca accaatgtac ctaacaaaat cgcacacaac
     2761 gaccccagag cggtaacaat catcaaccat tgccaacgtt caccaaagtc tacttgatag
     2821 ataaaacgaa agacagctaa cataatataa atctctgtca aaacaatcgt aaagcttgct
     2881 gccaaattag cgattgaaac taacgattgc tttctaggaa tcaaggacaa gcgaatacca
     2941 tttgacgatt gatttgcttg ctgatcctgt acattgcgga ccccccacat cgtcccgtag
     3001 agaatcgcca ttccaatcag agtgaagaaa taaaaacttt tgaaactcat attacgacct
     3061 gcatgaactt cttgaaaaga tacttcttgt tcaaaaacag tcatgatggg cgcgagatca
     3121 acgttctcca cttctgccac tttactcgaa attataccaa tacgctgtaa aaattgatcc
     3181 atgacgtttt tcatcaacgt ctgactcatt cctgcttgac ccacatggag cgaaacagat
     3241 gaaccatcaa tgagataaaa accagccaaa tcatctgcat ttagcttttc attcgcttct
     3301 acttccgata gttcctgtac ttcaaataat ggtttatcat tgacttcgac ttgttctaag
     3361 actgtggtaa aattttccga aagcgctgtt tgatccgctt tgattacaat tccagtatta
     3421 atcgtttcaa gattgccacc ttgatcaatc tcgccaaagg ccgccataaa catcaatcct
     3481 aaaagaattg gaaaggccaa tgtccaaaac aacatggatt tatttcgcag cagtattttt
     3541 gtgcgatatt tataaaaatg ccaaaacatt atttcccctc ctctagtctc tcaaatcctt
     3601 gccagtaatc tctaaaaaga catcattcaa ggacgcttct ttggttgcta tttttccgta
     3661 actgatcttt tcttcttgta agattgtaag aatcggcaac aatactgtat ttagttcagt
     3721 agttgttact tggagctgac cttttttata agcgattcca tcagaagcta ttgttcgctg
     3781 aatcgctgac aacacatttt ctgggagtaa tgggatgtcg atcgtcaaac gatccgccgt
     3841 ccgtaccata tcttttagag attctttggt tcctttagca atcacctgtc cttgatccat
     3901 gatcacgatc tggtcgcaaa gaatttctac ttcttccatg taatgtgttg tatagacaat
     3961 ggttgctcct tgtcgattca gctccttgat actttctaaa attttattcc gactttgggg
     4021 gtctacagct actgtcggct catctaaaaa aattaaccgc ggcttgtggg caatcccaca
     4081 tgcgatgttc aaccgacgtt tcaagccacc actaagttct cctggacgaa acgaaacata
     4141 tttttctaat cccactaatt gaatcacctc ttcaatcaag gctttccttt tctctttttc
     4201 ggaaacatat aaaccgcaaa aataatcgat attttcttgc acacttagtt cgtcaaagac
     4261 cgcaacgtct tgaggaacga ccccaatcat tgccttgaca gcataatttt caggagtcat
     4321 tgttgtcccg aacaatttaa tggttccttt gtcataattt aacaaagaaa gcatacagtt
     4381 gatggcagtc gatttcccac tgccgtttgg acctaacaga cctaagactt ctccttcttg
     4441 tacttgcaga tcaaaatgat tcaatgctac aaaatctcca tagcgtttga ctaatttatc
     4501 aatttcgata atcatcatga aaaactcctt ccaaatttct tgttgatctg actataataa
     4561 agtgcaagaa aagaaactag tgacgattgg ctaaaccaca catgacattt gtcacaatga
     4621 aggagtctgc tatgcataaa tctcggctac tcaacgaaac tagctttcta ctggttatct
     4681 cattgctttt gctggtaagt caaggattcg ttgctatgca agttatctat ttattgatcg
     4741 ccgttttatt cactggtgtc agttatttac tgcctacaaa gccaaattgg attttccaag
     4801 ttattctatt tcttttatgt gcctttttac ctgatcttgt cctgtttctg ccagcgacga
     4861 tgcgagtgat cgcccctgaa gaaagccacc ttgattactt gtttttgtta ggttttttgt
     4921 tgatttcgac ggttggtaat catcccccca tcaaggtcgc ctttgtcgta attttgctgt
     4981 ttttttcctt ttacttacga aaaaaagatc aacgaacgac cgatcttgag aaaaagtaca
     5041 ttgtctccaa agatactcat tgggaaaaac aacaagagtt atcggaacaa aataaagcat
     5101 tggccctgtc acaagaaaca caattagcct tgcaaattgt ggaagaacgg aaccgaattg
     5161 cccgagacat ccatgacaat gtcggtcatc tgctgtcaag tgcgatttta caaattggtg
     5221 cgcttgaaat gatcaatcaa gaaccaaaac taaaagaacc attagaaaat ttaagtgcca
     5281 ccgttcacac tgggatggat cggattcgtc aaagtgtcca tgacctccat gagacatcga
     5341 tctcttttca acactcctta gagtttctga tcgctgattt tccttcttct gttacgattg
     5401 aaggaaactt gtttgaagga ttgaatgaaa cgcagcaaaa ctgcttctta atggtcatca
     5461 aagaagcctt aaccaacagt atcaaacata gtcatgccaa aaccgttgtt ttacattttc
     5521 gaacgttgcc ggccttttat cgcttgcaaa tcacgaatga tggcaccagc ccacaaaaaa
     5581 attctgctcc cggtattggt ttgaaaacga tgcgtcaacg tgttcaagaa caaaagggac
     5641 aagtccatat tttccaagaa aaccagcaat ttcagttaac gatcatttta ccaagggagg
     5701 gacaccaatg ataacagtag tcattattga tgatgatcca tttgtgacga aatcgttaca
     5761 aaccatttta gaaagcacga aagagatccg tgtgttaggc attggtcatt gtgccaagga
     5821 tgcgcgaaac ccatcgtccc gatgttttgc tgacggacat ccgcatgcct aaacaaacgg
     5881 gcatcgatgc tgccaaagaa attttggcta aatttcccaa agccatcctt ttgcttttga
     5941 cgacattcaa agatgaagaa tacatccgcg aagcattttc catcggtgtc aaagggtatt
     6001 taatcaaaca gaacttgcaa gcgattattc cttctgtcaa atccgcttat aatggacagg
     6061 ccgtatttgg taatgaaatc atcgagactt tcactcaaat gatgaagaat aaaccgacga
     6121 ttgatagtca tgcttatgct tcttttagtg aacgtgagct tgcaatcatc aaagaagtag
     6181 ctgccgggaa aaacaataaa gaaattgcag atgccttgta cttgagtgac ggcactgttc
     6241 gcaattacat cagccaatta ctagaaaagc tagatttacg ggatcgcacg caattggcta
     6301 tctattttta tcagcatttg caataagtct tatctaacac aaaaaaacct gaatgatgct
     6361 ccttcgcatc attcaggttt ttttcacatc ttctattcaa ttgtcccgca aaccatttcc
     6421 tcacgattga aagaatcaag gattcgcagg gctgccagga ttcgttggat tgttcggcgt
     6481 gttaggcgga aaaataggcg ccttgtctaa cgttttttct agttttgatt cttcacgatc
     6541 gtctcgttct acatcaggac tttcattcaa tttgaattct ttttccatct catctaactt
     6601 tttaaagtca ttgccagatt cttttgctaa tttcgctaat ttatcttcgg tttctttagc
     6661 cataaagtaa cgcccccctt ttgatttcag cttagcatat cacactgaaa aaacaaaaga
     6721 aaacgctaac caacgatcat ttttagctat ttctcatctt taaaatcaag cattttttgc
     6781 cggtataaaa tcgtagggag aactgttttc cataccaatc atcggatcta ctaactggtt
     6841 atcgatcact tctgctgtaa gaacgaaatc tttagaaaca gcaggttcta cctcttcttt
     6901 cttttcttct ccaacaaatg aagaaaacag atctggttcc actgtttcca ttacttggtt
     6961 tttcgtttca ttcgtcccac tgtcatcttc tacaggtagc ttttctttta caacccgtgg
     7021 ctcttttgta tagttcccat cttcaaatgg atcatttccg accaaagaat cttcataagc
     7081 tgctagtttg gtccggagag tgatattcat tttatcatta tccatgatcc ttgatttcaa
     7141 cgtagtcatc cggcttgctg attcattcgc tacacaagtg acataggctt gctcttcccc
     7201 taacaaaatc aacagttcct tactgcgagt cactgccgtg tagagcaaat tacgctgaag
     7261 catccgctga tattgatgga ccatgggcaa aataaccatc ttgaattcac tgccttgtga
     7321 tttatggatt gagcaacaat aagaaagagt gattttattc cattcgtttc ttttataagt
     7381 gacctcattt gcatcaaact ggataactaa ttcatccact ttatcttcag aatcttttgc
     7441 caagatgata cccgtgattt ctcccatatc tccattgaat acattcaatt cgggagtatt
     7501 gactaattgg aggactttgt ctcctatccg ataaacggtg tcgttccaat gtacttcctt
     7561 ttttccaggt ttccctggat tgaatatctc ctgcatcatt ttatttaacg catcgatccc
     7621 tgcaggtccc cgatacattg gtgctaatac ttggatatct tgtgcacgga atcccttatt
     7681 tttcgctttt tccacaattt tagagatcaa gggttcaatt tgataagcat cacttcggaa
     7741 ataggaacga tctttttgat tctttgtgaa atcttttggc agacgtcctt ctttgatctc
     7801 atgggcaaga ggaataatac tagaaccatc accttgccga taaatctgat tgagttccat
     7861 tttgggaatt tgttcgattt ccaaaagatc atggagtact tgaccaggac cgacagaggg
     7921 aagctgatct ttgtctccta ctaagataac ttgcatattc gtcggaatcg ctttgaataa
     7981 tgtgttagcc agccatgtat cgaccataga catctcatca acaatcaaaa gtccgccttc
     8041 taattctttc gtactgactg aaggtgtttt ttcccgtcca ttcagcccca gaagacgatg
     8101 gatcgtactg gcaggcagac ctgtcgtttc gttcattcgt ttagctgctc ggccagttgg
     8161 tgctgcaagt agaataggaa aaatttcttg ggtatatttt gaaggatcca attccagtcc
     8221 gttcaactct gcaaaaagat tgacgattcc gttgatcaca gtagttttcc ccgtacctgg
     8281 tcctcctgtt aaaataaata gaggggaacg gattgcttca gcgatagctt gttcttgcga
     8341 aggtccatac tgtatgccga atattttttc gatacgccga atattcttct gcacttcttt
     8401 ttcaggataa tggatttctt ttttacgact gagaaggcgc tggatcgaat taccgatccc
     8461 ccattcagaa aagtacaaac tgttttcgta aagattagtc tcttcttgtt gtatctttcc
     8521 ttcttcaaca agttggataa ttacagtagc aacctgatca ggctggattt caattgggcg
     8581 acttgtttct aaaatacgga tcgtttgctg aagcaatgtc tccgccggta cgtatgtatc
     8641 tcctgtttga actgcatgct gaaaaatctg atgcaagata gctgctcgaa ttcttctcgg
     8701 tgaatctgct gcaataccga tttgttcggc tagattatct gcacgtttga acccgattcc
     8761 ttctatgtct tcgactagct ggtacggatt ttcttcgatg atatccaaag actcgttctt
     8821 ataggcctgg tagatactga aagctaactg actaccgaac ccgtaacgat tcagtcccat
     8881 gatcacttga tccatcccgt ggtttagccg aatcgtctca gcaagcattt ctctttttgg
     8941 cttcgtcaaa ccggagattt gttttaatac cgaaggatca gcaatgattt tttcgatagc
     9001 atcttctccc agcaattcta caattttttc tgctgttttc ttcccgattc ctgggaattt
     9061 ttcgctggaa agatacgcta cgatcccatt tgcagttgtt ggcttttctt gctcatatct
     9121 ttcgagttta agctgccttc cgtatttagg atgatccact aattctccat aaaaacgata
     9181 agtctcattt tcttgaatat cgccgaaact tccggtgact acaatctctt tttcacggta
     9241 atcagctgtg gtttcactga tgtgtaccaa aagcactttg taaaaattac taggattttg
     9301 aaaaaaaatc gcggcaactg taccaacgaa ataaggcatt tcttctggct gcatcggaag
     9361 ccgcctcctt cttctatagt aaaggttctg gtgctgtttc agttcctaaa aaatctgttt
     9421 ggttccatac tttcagttca tatggcaata atctgcaagg ctcttcagtc tctaaaatcg
     9481 tcaaactact attgaacaat ccacccattt cacgcaactc acttagctct tttcctgtca
     9541 tccattgaat ggctgcagtt aaagaagctc catgtcctac gaataaaagt gggccatctt
     9601 tatgtcgggc aaccgcatct gctacaacag tttcgatacg tgtgattgcc gattcaatcg
     9661 tttctccgtg aaaaggagaa ggatcataca gatctaaatg attacgcaaa ttcggcagat
     9721 tatccggata tttctggtac atttcatcga tcgactgacc ttctaaagta cccagcccta
     9781 gttctcttag cttatctgta taaaaaatct ctaccggacg agcaagctct ttgttgatac
     9841 cttctgctgt atcacgtgct cgctttgctg tactggaata aattgcttta aaaggaacat
     9901 attttacctt tttcccaaat gctttgattt cttcgtaact ttgtggcaaa agcggagaat
     9961 cgccattgct cccttgaaaa cgtctttcct gattccattg tgtcttccca tgtcgggtaa
    10021 aatatagttc catacgcagc aaactcctgt ctttctttta ttttactcta taataaactg
    10081 tctaatccag cttgtcattt tcatagtgat gcgtcaattc taaattaggg aatccttgct
    10141 ggcgaagtgc ttcatacact atcattgcag ctgtattcga taaattcaat gagcggacat
    10201 gctcatcatt catagggatg cgtaaacact tttcttcgtt ttcacgcata aatgtttctg
    10261 gcaaaccggt tgtttctttt ccaaataaaa agaagtgctc ttctccatca gcaaaatttt
    10321 cgtcactata tactttatgg gcaaattttg agatcaaatg tagtttacga ttacctaaaa
    10381 atgttaaaaa agcttctaaa ttactgtggt aagtaatatt tacatcattc caataatcca
    10441 accctgcccg ttttagatgt ttgtcatcag ttgaaaaacc tagtggctcg attaaatgaa
    10501 gcggagtatt cgtggctgca cacgtacggg caatatttcc agtgtttgca gggattaatg
    10561 gttcaaataa aacgatatga ttcatcagga tcattcctct catatttatg ttcgtttcta
    10621 ttttctgaca atttgatttt tgcataaaaa aaaacgtatc aactcggtgt cagtcactgc
    10681 gagtcgttac gttagtgaag ctcttctcac taacttttat cagaacagga acctgataaa
    10741 aaccaatgaa aaaacaactt gttgctaata taacaccctc aacttttttt tgcaacctct
    10801 actcattaaa aactgctaga aaaacgtttt ctcttagttc cttttaataa ttctatgtca
    10861 attgtaatct tcttcaaagg attcttatat aagtctgctt tgattcgctc ttctacctgc
    10921 cattctaaag gtgacatggc caaaagatct ttttgatttt cctctggtat ctcaaattca
    10981 taggttacac gctgacgttc agttaatttc attgcttcag caaacttggc tactacacgt
    11041 tcattggaat aactctgttt ttcaggttga ttcggataaa aagcctgacg tagttccttt
    11101 aaataatttt cttgtggcac caccttcaac acttctccat cttctgagag tacacgttgg
    11161 aattcttggt aatgagaagg cgaaaagata tttaaaaccg cgttgaatgt ttgatcagca
    11221 aacggcaaat tggtcaaatc agctacacac caaaatgctt cggcagattg ttctgtagct
    11281 gcgtagactc cttcttttga aatatcaaat ccaacagcat tttgaatctt tttcaatttt
    11341 gaaagttcat tcaagaagct accttctccg cagccaacat ctaatagcga gacttcttca
    11401 ggtaaatgct gcgcaatagt ctcaataacg ggctgataca tgccagattg gatcattcta
    11461 cgccttggaa cgaacattcc ttgatcgtat tctgttttaa ccgcatggga taaaaaataa
    11521 agtgttcctt ttttggaaag gtcaaaacgg tgattatttt tgcatatcaa gccattatca
    11581 gactttttta cttcttcttg gcaaaccgga cagcggaaca gctgatgatt ttctgccaaa
    11641 aactggcgtc ctcggtcaat tttttttaac atagttcccc ctcatttctg ttttatctta
    11701 ccgttagatg ctcactttgg caactgctaa aaatatgata caatgcctag aagaaagtga
    11761 aagataaagg agaagattag atgatcaaag aattttgcgc tgaaaactac acatctattc
    11821 ctctagcaat tgctagagga gccgatcgga tcgaattgtg tgacaactta gcggtcggtg
    11881 gcacaacccc gagtactggt gtgatcgaag aaacgttaag ttatgctggg gaaaaagata
    11941 tccccgtaat gacgattatt cgtcctagag ggggcgactt cgtctataac gatatcgaat
    12001 tgaaaatcat gcatactgat ttgattgaag caaagaaatt agggacggat ggcgtagtat
    12061 ttggttgtct tactccttca ggctggctag acgaagaggc cttagaacta ttgatcgaaa
    12121 cagcagaagg gttgcagatc accttccata tggcttttga cagtattcct gaagatcggc
    12181 aattcgaagc aatcgattgg ctggtagaac atggtgttga ccgtatcttg actcatggcg
    12241 gtcctgctga caaaactatt gtagaaaatt tcccacggct taaagaattg attgcctata
    12301 cagatggccg cttaatcatt ttgcctggtg gtggtgtcac tgcagagaat gcagcacatg
    12361 tagctaaaga attgaacgta agcgaagtac acggaaccaa aatcgtggat cttcagttat
    12421 aatcttataa acaaaaaaac atttgcaaca gtcataatgc ttattgcaaa tgtttttgtt
    12481 tttttacata aaatagccca taaataaaga agcaatattg aaataaatca gtacactcgt
    12541 caaatcgctc aaagtcgtga taaagggacc gcttgctact gctggatcaa atcctagacg
    12601 atccattagc atcgggatta aactacctgc aagattcgcc actgtgattg caaatagcat
    12661 agccatccct atgacaaacc ccaagataaa attatgtttc caaaaaccta cgattagaaa
    12721 aatcgtgatc cccgtaacag ctcctgtgac aacgccggtc aagacttcag ccaaaacaag
    12781 tcgaacaaat ccatgatctt tctcatcaga aatcgcaagt cgacgaacag ccacagctag
    12841 cgactgggtt ccagcattac cggcagttcc tgtaatcagc gaaatgaaga ctgctaaaat
    12901 actcgcttca cttaccaagt cttcatagtg actgattaaa gaagcggtcg acatacctaa
    12961 aaacaacaga gtgatcagcc aaggcaaacg tcgagacgct gcctttactg gattttcatt
    13021 aatttcttcc acattgaccc cggcaagtcc tgaataatcg ctagcagctt catcatcaat
    13081 aacgtcgatg atatcatcga ctgtgacgat tcctaacaaa tgatcatcat aatcggtaac
    13141 aggaagagct aagaagtcat aatctctaaa tgtttgtgcc acatcttctt ggtcgtcgcc
    13201 tacatgaact gaaagcactc gttcgctcat cagatcagaa atcattgcgt cgtcatcatt
    13261 cacgattagg tcgcgcagag aaataacccc tactagctga ccttcttgat taacgacata
    13321 gatgtaatag attgtttcag ctacatctgc ttcgttcttc agcacgtaca tcgcagagcg
    13381 aacagtttga ttggctacga tcgaaacaaa ttcagttgtc atgatcgcgc cagccgtttc
    13441 atcctcgtaa tggagaagtt ccttgatttc actggcatcg tctgccgaca tcaaacttaa
    13501 atatttagca atttgctttt tatccagcgt attaagcaag tcaacagcat tatctgtata
    13561 catctcagaa agcatatcag ctgcatagct aggacgcatt tcatctaggt attctttcat
    13621 atgttcgttg tcttcttcaa tcacatcgaa catatccgct aattctttag gcgacagata
    13681 ggaatagatc agctgcctgt tctcttctgt aagagattgg tagaattgcc cctgctcata
    13741 gatatgcatc tctaaaaaac tgtttctgaa tgcctgaata ttattttccc ttaaatcttg
    13801 agtcaactgg gcaaatcttt cctctaattc ttgattttca tccaaaccaa tctcacctcg
    13861 ccttattctt caaaccgtct cacaactgcc tccatgtctg cggctaaagg ctgcttgaac
    13921 tccagcaact cttctgtaaa tggatggtaa aaacgcagat cataacaatg aagggcttgt
    13981 ctttttattc ccagatccat tcgcccgcca tacatatcat caccgagcag ggcacagcca
    14041 attgcggaaa aatgaactct tatttgatgt gtccttcctg tatgcagctg gatatcaact
    14101 aacgcgattt ctgttagtcg cttctctatc cagtactcag tctgtgccga acgtccttca
    14161 tcagagacca ttcgcttcaa tagcgaagaa taatctcggg cgatcggcaa atcgatatgt
    14221 ccatgtgccg ataaatctga aagccttcca ctgactaagg cctgatattt tttcacaaac
    14281 ttcttttcac gaagttgcat atctaatttt gcgtgcgcaa atccatgctt tgcaaaaagc
    14341 atcaagccag atgtatcccg atctagtcgc gtcaccacat ggattacttg gttttcgtaa
    14401 ccttgttttt tataataagc ctttacacga ttagccattg tcccatttgg atggtattgg
    14461 gcaggaatag acgaaacgcc tgctggttta tttactacca gaacgtgttc atcttcatac
    14521 acgatatcga tcggtgtttc atccaaaagt acggtttcat gttctccttc agcaggaatc
    14581 acaatggtta ccttatcatc cttagctaga gaaaacaaga cattttctac ttgatcatta
    14641 actttgattt gaccgccttg aaattttatt ttcgctaaca gaccctttga gatccctttt
    14701 tcttttaaaa aatattttac ttgctgagaa tgatctttct cataatccca tgtaaactgc
    14761 atatcaatcc tcactaataa aggcatcttt cacacgatgc caaaaatgca tatgtcgata
    14821 agaagcaaaa tggatccgtt cttctgctat tcgataataa attgagcgga tatttgcttt
    14881 tgcgacattc aattgatcaa ccgttacaag ataatcttct gtattttcca attttatttc
    14941 tagccattca tcatgggcaa tcacgatcgg agaacccaaa gtacgaaaca ctcgattatt
    15001 cagtgaagca atctctgcca actgaaaggc attgatacta ggatggatca cagcaccgcc
    15061 gacactttta ttatatgctg tcgaaccagt aggcgtagaa atcgtcaatc catctcctct
    15121 aaaactttca aacagctcgt ttttgatgta tacatcggct accatcgtac gattggcccg
    15181 tttaatcgtt gattcattca gtgctaaaaa atgctggtcc ggtgtttcat ccaaataact
    15241 gatccgaaca tccagcaagg gataactaac actttgttcc cggttcgttc gtaagctgtc
    15301 tactagttct tccagctcgt aatcccgcca atccgtgtaa aaccctaaat gacctgtatg
    15361 cacgcccaag aaacgcacat cattcagaca atgactgtag tgatggaacg ccgacaataa
    15421 tgtgccgtct ccgccgactg agatgaccaa ttctggctca tgatcatctc gttgaatccc
    15481 tgcttgttct aaaagtgcgt tcaaacgttc tgtcacttct atagtctttg cttctttatt
    15541 atgaacgatc gctactttca tcccctgcct cctctctttc gctttctttc ttcaaaagcg
    15601 ttcgatagta gacatcatct gattttcctc ttccatggga gaataaccgc tgtgcttctt
    15661 ggatttcttc acggatactg gacatctctt catccaactg ataggcagct tctgccgcac
    15721 gctgaagtcg ttcactcatt tcttctggaa aaacgccttg atatttataa ttcagcgaat
    15781 gctcaatcgt tgcccagaaa ttcatcgcaa gagtccgaat ctggatttcc gccaaaattt
    15841 tcttctcacc gctgatcagc tgtacaggat actcgatcac cagatgataa gaacggtagc
    15901 cacttgcttt tttatttgtg atgtaatctc gttcttggag aactttcatg tcttttcttt
    15961 tacggatgat ctcaacaact tgatggatat cttctacaaa ctgacacatg atccttaacc
    16021 cggcaatatc agacatttct tcttctaaac gtcccattgg aatatgccgt aattgtgatt
    16081 ttgttacaat actatcgact ggcttgactc tcccagtgac aaattcaatc gggacatgtc
    16141 gattttgttc acggaactgt ttgcggatcc cccgcagttt cactttcaat tctgatacag
    16201 tttgttcata tggtgctaaa aatgcttccc aatctcgttc catagctgat acctctactt
    16261 cattaacatt cattgtttat tctaccatat atgcaaagtt ttttcgtact cttgatttat
    16321 gcattgacca aaaaaagaaa attaggcaaa atagacaaaa aggagtcgat caaatgacac
    16381 aaatgcttga aatcgaatat aaatctatgc tgacaaagca agagtacgag atattcatcg
    16441 ctcactatca attaacagat aaagatttcc gtgtacagac taatatttat ttcgataccg
    16501 ttgatgaaca gctgaagaaa caaaattgtg gcctacggat ccgtttcgtt ggtcatcaag
    16561 ctgaatatac attaaaaaca cctgctgaaa aagggcgtct cgaaacaacg gataccttta
    16621 taacagaaga agcagaagca tttatcttcg aaaaacgtct gcctcgttca ggcgcagttt
    16681 ttcaaaaact ttctgatttg aatatcgatc ctgcttcatt aatccaaacc ggaaagctta
    16741 caacaaaacg agctgaattc cctattgaag aaggactttt agctattgat gaaagctggg
    16801 gagacaatct acacgatttt gaactggaac tagaggtagg ggatgcatct gtgggaaaaa
    16861 ttgcttttat aaatttttta aaacgttttt ctttacctta tcgtcctgct aagaacaaga
    16921 tccaacgtat gcttgaagct aaaaattaga aacctttcat tttcacaagg cacttgagtt
    16981 cattttttta cttttttctg ttaagttata ggatgtgaaa gaatctagtc actagttgta
    17041 tagaatctat tttgggggag attcatatga tcgaaatcta tttatttgtt aatcctttag
    17101 gggaatactg tttcgaaatg gaacaacagt tattacaatt tatcgaagaa gagtacggga
    17161 caccatcaaa agaaaagatg caatttcgct ttcttccttt ggtcaatttg cagacaattg
    17221 gggatgtcat gcaacaaaaa ggaatttctc agaacaatct tgaggaacgt aatcacttat
    17281 tctcaatgac ttattctgca gcattggact gcaaagcggc gcagtttcaa ggaaagaaaa
    17341 aaggccgccg ttttttgatc aaattgcaag aagcagtcgg ctgtaatgac ataccatatt
    17401 ctcaagaact tgctgaatcc atatttgaag aaatcggcgg cgatttgaat atgtttaaag
    17461 aagatcgtca gtctgacttc gttaaagaag tattcttttc tgatcaaaaa attgctcggg
    17521 aaatgggcat cacaaaacac ccttctgcag tcgtttacaa ttatgcctgc gaccgtgatt
    17581 ttggtgtttt agtagaagta aaaggtacaa gtagcctttg gagaatcaca gagctgtgta
    17641 aaacaacaga taactcatat caagttttta atggtgaaca tttacataca aatgattctc
    17701 agttccattc aagaactagc catttacact tgctttctaa ttaaaa
//
LOCUS       DAIGSZ010000061        17305 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.061, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000061 DAIGSZ010000000
VERSION     DAIGSZ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.061"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..115)
                     /locus_tag="NOB31_002167"
     CDS             complement(<1..115)
                     /locus_tag="NOB31_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI0974359.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            645..1040
                     /locus_tag="NOB31_002168"
     CDS             645..1040
                     /locus_tag="NOB31_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974360.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            1365..1982
                     /locus_tag="NOB31_002169"
     CDS             1365..1982
                     /locus_tag="NOB31_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0974361.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            2023..2322
                     /locus_tag="NOB31_002170"
     CDS             2023..2322
                     /locus_tag="NOB31_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HCI0974362.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            2356..2523
                     /locus_tag="NOB31_002171"
     CDS             2356..2523
                     /locus_tag="NOB31_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCI0974363.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            2544..2885
                     /locus_tag="NOB31_002172"
                     /pseudo
     CDS             2544..2885
                     /locus_tag="NOB31_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(2965..4257)
                     /locus_tag="NOB31_002173"
     CDS             complement(2965..4257)
                     /locus_tag="NOB31_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0974364.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSECRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
     gene            4324..4635
                     /locus_tag="NOB31_002174"
     CDS             4324..4635
                     /locus_tag="NOB31_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0974365.1"
                     /translation="MFWKIKKMLVSSTNIKKYRAKKIKERQAQGIEIAKKKGKFKGRQ
                     HKFKENDPRLKHAFDLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRD
                     S"
     gene            4635..6779
                     /locus_tag="NOB31_002175"
     CDS             4635..6779
                     /locus_tag="NOB31_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HCI0974366.1"
                     /translation="MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDPLFTDETFIT
                     FGFGHLVELAEPGHYDEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAELLKKANT
                     IIVATDSDREGENIAWSIIHKANAFSKDKTFKRLWINSLEKDVIRSGFQNLQPGMNYY
                     PFYQEAQTRQIADWLIGMNASPLYTLNLQQKGVQGTFSLGRVQTPTLYLIFQRQEAIE
                     NFKKEPFFEVEASIKVNQGSFKGVLSPTQRFKTQEELLAFVSSKQAKIGNQEGIIADV
                     QTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYEAKLLSYPRTDTPFITE
                     NEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHHAIIPTKQVPTESALAK
                     MDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKVADLLFQSIGKTPKQEGWKILFKQ
                     QTKEEKEDVQTLPLVIIGERAEVGVKSVEKETQPPKAFTEGTLLTAMKTANKTVDDEE
                     AIKILQEVEGIGTEATRASIIEALKQKEYIQVIKNKLVVTEKGKLLCQAVESQHLLTS
                     AEMTAKWETYLKKIGKREGNQENFITNIKKFIVHLLEAVPNDIEKLNFSDYQEQKEKE
                     AEKSIVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFRKKKLTKTNVKELLEGKET
                     LVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            6899..7138
                     /locus_tag="NOB31_002176"
     CDS             6899..7138
                     /locus_tag="NOB31_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HCI0974367.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            7187..7271
                     /locus_tag="NOB31_002177"
                     /pseudo
     CDS             7187..7271
                     /locus_tag="NOB31_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            7396..8133
                     /gene="erm(B)"
                     /locus_tag="NOB31_002178"
     CDS             7396..8133
                     /gene="erm(B)"
                     /locus_tag="NOB31_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCI0974368.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(8330..11296)
                     /locus_tag="NOB31_002179"
     CDS             complement(8330..11296)
                     /locus_tag="NOB31_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HCI0974369.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            11442..12017
                     /locus_tag="NOB31_002180"
     CDS             11442..12017
                     /locus_tag="NOB31_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0974370.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            12231..12926
                     /gene="vanR"
                     /locus_tag="NOB31_002181"
     CDS             12231..12926
                     /gene="vanR"
                     /locus_tag="NOB31_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCI0974371.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            12904..14058
                     /locus_tag="NOB31_002182"
     CDS             12904..14058
                     /locus_tag="NOB31_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HCI0974372.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            14273..15241
                     /locus_tag="NOB31_002183"
     CDS             14273..15241
                     /locus_tag="NOB31_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HCI0974373.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            15234..16265
                     /gene="vanA"
                     /locus_tag="NOB31_002184"
     CDS             15234..16265
                     /gene="vanA"
                     /locus_tag="NOB31_002184"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HCI0974374.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAFITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            16271..16879
                     /locus_tag="NOB31_002185"
     CDS             16271..16879
                     /locus_tag="NOB31_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HCI0974375.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         5756 a         2981 c         3470 g         5098 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca gaagatttat accaagatgt tgacgcggta aatgtttata ccttagcaaa
      241 aagaaattct gattcaacag ctttatcggc tttaaaaacg tactattgtg ataagggtgc
      301 tattgataga tttaatcaat ttgttaagaa cagatttggt tcttcagata aaatcgcttc
      361 agtaacaaat agtttattag aaaatgacga aacagttgat atcttaggtg tagggataat
      421 ttcatttttc attgataaaa tagttaataa ttcacttggg acagatttta cttatcttga
      481 ttttattgga gatgagggga aagttgcaaa tggattttct gaaaaaatta ttcaatttca
      541 agaaaataga agtaaactta attaagaatc gtttactatt taaacagtgt ccttttcctt
      601 tttaaatata tacgataaaa taagtatatg aattgtaaaa ggacatgatg attatggaag
      661 aaatagaatg gaataatctg actcaaaata ataaaaataa ttctggatgt ggaattatct
      721 ttatgtttgt tatagttttg ggaatagtag tacttttaat aactgtcaag atagtagatt
      781 actttgcgaa tactcctgaa gaacaaatac agagaaaact tcctgagttt gaaagagtac
      841 caccttatga tccaagagat aattcatttc aagtaaaaaa attaaaagag tctccaaatg
      901 aaatgtggtt tgaagttaca gttgaatcaa gcgacttcaa agaaaaaaag aaagaataca
      961 attatattgt aaaggcaaaa gtatcaaaaa gatttatttt taaccctaaa ttagaaatat
     1021 atagtgttgt aatagaataa tagtgttaaa aaaattgtaa aagttaaaga agtcaaattc
     1081 tgatgtgaaa aataaaatat accatggaag acataaaaga aaaactggat aactagttta
     1141 tttaatggca gaccgttaag gcctgccatt tttatgtatt ttagcggaat aaatataatc
     1201 atgcgggagt gtaaacttac tgtttcaaaa agtatacttt ttgacatgcc ttgattttct
     1261 ttgtttatgt atggcataat aaccacataa tacaatttga aacgtttctg atttaatctg
     1321 attgttttga aacaatttta gtgaaaaaag ggtagataaa aacgatgaga aaattttttt
     1381 atatccgggt cagtagttat gatcaatcga tcgaacgaca actgatttcc gcgaaggaat
     1441 taggaatccc tgaagaatat atatttgtag aaaaagccag cggcaaagat tttaaacgcc
     1501 ctgaatatca attaatgaaa cggatgtttc gaaaaggaga tttactctat ctacaatcat
     1561 tagatagact aggcagaaat aaacaaatga ttttagaaga atggcgagaa ttaactaagg
     1621 aaaagcagat tgatatttct gtgttagaca tgcctctgtt agatactgct agttacaagc
     1681 aactagatgg gttagagacg cttatctctg acttaattct gcaattactc agctatatgg
     1741 ccgaagacga gcggaaacga attaatagcc ggcaaagaga aggcgtagaa gctgcgaaac
     1801 aaaagggtgt aaaattcggc agaaagaaaa ttgctttacc tcctgaattt cctgcgatct
     1861 attctgactg gaaagcagga aagataactg cagtctatgc tatggatcaa ttgggcatga
     1921 aacgaaatac cttttatcga cgggtgaaag aatatgaaca taccttgcac cacttttctt
     1981 gatagatata acagctatta gacgggaagg gagagtttga aaatggactt aacgaatcaa
     2041 agggtcgttt ttactggaac gctgcagcaa atgacacgaa cccaagccat cggtttggtt
     2101 cactctttaa acggccattg tcaatcaagt gttacttcaa aaacaaattt cctggtttgt
     2161 ggtcagtatt ctaagtcgtt gtttgatgat tctctctata caaaaaagga acaaaccgcg
     2221 cgggacttga ttgcgttagg tcatgagatt accattttat cagaagtcga attttatgcg
     2281 ttaattagtc aacagttgaa agaatggcaa cggtatttat aatcgttagt aaaatttaca
     2341 aggaggaaaa tttttatgaa gcgaaaatct tatgatcgtt ggggcattga aataactagt
     2401 tttaatcgaa atattgcttt tcacgtggag tgtgactgtg gggaattagc aaaaagtgtt
     2461 tatcaaaaaa attactttta ctgtcctaaa tgccatcgcc gatacggggt acatggaaca
     2521 tagaaacgaa atagtgcggt agaaaagaac agaacttaga tcggcaatta caagcgttac
     2581 agggcgtttc taaggtcttt tcagacaaat taagcggtca atcggtcgaa cgcccacaat
     2641 tacaagctat gcttaactat attcgtgaag gggatattgt tattgttact gaattagatc
     2701 gattaggacg aaataataaa gaattaacag aattgatgaa tcaaattcaa attaaggggg
     2761 caaccctgga agtcttaaat ttaccctcaa tgaatggtat tgaagatgaa aatttaaggc
     2821 gtttgattaa tagccttgtc attgaattgt acaagtatca agcagaatca gaacgaaaaa
     2881 aaatggctct ttgtcaaatg atgttggtaa agagaaatct tagaataatt ggagatcaag
     2941 tggatcagtt cctcttgatc ttttttagtt gaaaatcaat gcgttgccat gacgaatcat
     3001 gatgcgcaat ttgaaattat aaaagctacg aaagccatat gcatttcgtt ttaacacttt
     3061 gatatggttg ttcagacatt caagtgggcc atttgaataa ctttgttgta aagcattttt
     3121 gatttgtggc agaaatttct ggaacgttct caaggtcgtc tgatagcctt cgggaagcat
     3181 gatattattg gtaagtagtt cttcaaacga tacgtagtct cgttccttta cagcgtaaag
     3241 aaagtcttga tataactgat agcctacacg caaagcaggg ctccctttca gtaagcgatc
     3301 cacaatatcg gtctctgtta aatgagcttt gaagccaggt cgccaaaggc gtcgagtata
     3361 atcaagcttg cgttcatctt tttgaagaag tttccagtat ctttttaatt gcttacctaa
     3421 ttgatagtgt ttttgttctt tgctttttaa tagttggttc gtttctttga ttcgatgatt
     3481 gcgaaaggta cgaccaatat gttggacgat gtgaaaccgg tcaataatca gctgtgcttt
     3541 tggaaacagc tttttaacga gcgatacata aggagcgtac atatcaatca cgatccattc
     3601 gaccgcttca cgaatttctc gtgaaaaatg actaaaataa cgttttaaaa aaggcagttg
     3661 tcggttctcg acaatgtcca acaagcgctg tgtttgtcca tccatcatga tgaaactcat
     3721 agcacctgaa acaccccgaa ctgatttgaa ttcatcaaaa caaagtacct taggtaacgg
     3781 tgtccgaaaa ggattcaacg gacgataaaa tcgcttcata atacggtaaa cagaagagac
     3841 cgatagattt ttctgagcgg cgatctctgt cattgaggta ttttttttca gacgagtcac
     3901 gacagaccag cggactttct cactgatgaa acagtgtttt ttcgcaacag aagtatctgc
     3961 gacaaaggtc cgctgacaag ctttgcattt gaagcgttgc tttttcaatt cgaggtaggt
     4021 acggcattca gaaacatcgt tcattaacaa ccggacggtt gttgtacccc aacgcacaat
     4081 atctgaagca atctggtgtt tacagtggat gcattcttgg gctgtataaa tcaagtttcc
     4141 acgataaata tgacagattt gccctttgta tttttctttt gtgagacaat tttcgttaaa
     4201 agtaactgat aagtctagaa tatctaatgt ttctttgata aggtgagtgt aagacatctt
     4261 gattcctcct tttgggttgg ttcgccaaat taattctaaa ggatttcaag gtgtcttttc
     4321 tatatgtttt ggaaaataaa aaagatgctg gtgtcatcca ccaacatcaa aaagtataga
     4381 gctaaaaaaa ttaaggaacg tcaggcacaa ggaatcgaaa ttgctaagaa aaaaggcaaa
     4441 ttcaaaggtc gtcagcataa atttaaagaa aatgatccac gtttaaagca tgctttcgat
     4501 ttgtttttga atggtttatc cgataaagaa gttgaagaac aaactggaat caatcgccga
     4561 acgtttagaa ggtatcgagc aagatataac gtgacagtcg atcaaagaaa aaacaatgaa
     4621 aagagggata gttaatgagt acggttattt tagctgaaaa accaagccag gcattagcct
     4681 acgcaagtgc tttaaaacaa agcaccaaaa aagacggtta ttttgagatc aaagacccac
     4741 tatttacaga tgaaacgttt atcacctttg gttttgggca tttagtggaa ttagcagaac
     4801 caggtcatta tgacgaaaag tggcaaaatt ggaaacttga atctttgccg atttttcctg
     4861 atcgatacga ttttgaagtt gcaaaagata agggaaagca gtttaaaatt gttgcagaac
     4921 ttctcaaaaa ggcaaataca attattgttg caacagatag cgacagagaa ggtgaaaata
     4981 tcgcctggtc gattatccat aaagcaaatg ccttttcaaa agataaaaca tttaaaagac
     5041 tatggatcaa tagcttagaa aaagatgtaa tccgaagcgg ttttcaaaat ttgcaacctg
     5101 gaatgaatta ctatcccttt tatcaagaag cgcaaacacg ccaaattgcc gattggttga
     5161 tcggcatgaa cgcaagccct ttgtatacgt taaatttaca acagaagggc gtacaaggta
     5221 cattttcact aggacgtgtt caaacgccca ccttatacct tatttttcag cgccaggaag
     5281 ccatagagaa ttttaaaaaa gaaccttttt tcgaggtgga agctagtata aaagtaaacc
     5341 aagggtcgtt taagggcgtt ctaagcccca cacagcgttt taaaacccaa gaggagcttt
     5401 tagcttttgt ttcttctaaa caagctaaaa taggcaatca agaggggata attgctgatg
     5461 ttcaaaccaa agagaagaaa acgaatagtc cgagtttgtt ttctttaagt agtttgcaat
     5521 caaaagtcaa tcagctttat aaagcgacag cgagccaaac tttaaaagct atgcaaggac
     5581 tgtatgaagc aaaattattg agttatccaa gaacagatac accatttatt acagagaacg
     5641 aatttgctta tttaaaagcg aattttggca aatatagcgg ttttttagga cttgatcttg
     5701 aaatggttca aacagagcct agaaagcgtt atgtggacgg tagtaaggta caggaacacc
     5761 acgccattat cccaacaaaa caagtaccta ccgaatctgc attagcgaaa atggacgatt
     5821 tacaacgaaa aatttatgct ttagtcgtta aaacgaccgt tgccatgttt ttacctgatt
     5881 acttgtatga agaaaccaag atacaaacga aagtagctga tttgctgttt caatcgatcg
     5941 gaaagacacc aaagcaagaa gggtggaaaa ttcttttcaa acaacaaacc aaagaagaaa
     6001 aagaggacgt tcaaacgtta ccactcgtta tcattggcga acgtgccgaa gttggtgtta
     6061 agagtgttga aaaagaaacg caaccgccaa aagcttttac agagggtaca ttattaactg
     6121 ctatgaaaac ggcgaataaa acggttgatg atgaagaagc aatcaagatt ttacaagaag
     6181 ttgaggggat tggaacagaa gcgacaagag caagtattat tgaagcgtta aaacaaaaag
     6241 aatatatcca agtgattaag aataagcttg ttgtaactga aaaaggaaaa ttattgtgcc
     6301 aggcagttga aagtcagcac cttttaacga gtgctgaaat gacggctaaa tgggaaacgt
     6361 atttaaaaaa aatcggtaaa agagaaggca atcaagagaa ctttattacg aatatcaaaa
     6421 aattcattgt tcatttactg gaagctgtac ctaacgatat agaaaaacta aatttttctg
     6481 attaccagga acagaaagaa aaagaagcag aaaaaagtat tgtaggaaaa tgtcctaagt
     6541 gtggcaacaa tattgtatta aaaaaatcgt tttatggttg ttcaaattat cctgaatgta
     6601 agtttacttt agctgaacat tttagaaaga aaaaactaac caaaacgaat gtaaaagaat
     6661 tactggaggg aaaagaaacc ctggtaaaag gaatcaaaaa caaagagaaa aagccctaca
     6721 atgccgttgt aaaaattggg gaaaagggat atattgattt tatatctttc tcaaaataaa
     6781 cataaaagcc ctttaaagag ggcttttata tattaatcac aaatcactta tcacaaatca
     6841 caagtgattt gtgattgttg atgataaaat aagaataaga agaaatagaa agaagtgagt
     6901 gattgtggga aatttaggcg cacaaaaaga aaaacgaaat gatacaccaa tcagtgcaaa
     6961 aaaagatata atgggagata agacggttcg tgttcgtgct gacttgcacc atatcataaa
     7021 aatcgaaaca gcaaagaatg gcggaaacgt aaaagaagtt atggaaataa gacttagaag
     7081 caaacttaag agtgtgttga tagtgcatta tcttaaaatt ttgtataata ggaattgaag
     7141 ttaaattaga tgctaaaaat ttgtaattaa gaaggaggga ttcgtcatgt tggtattcca
     7201 aatgcgtaat gtagataaaa catctactgt tttgaaacag actaaaaaac agtgattaca
     7261 cagataaata aatacgttag attaattcct accagtgact aatcttatga ctttttaaac
     7321 agataactaa aattacaaac aaatcgttta acttctgtat ttatttatag atgtaatcac
     7381 ttcaggagtg attacatgaa caaaaatata aaatattctc aaaacttttt aacgagtgaa
     7441 aaagtactca accaaataat aaaacaattg aatttaaaag aaaccgatac cgtttacgaa
     7501 attggaacag gtaaagggca tttaacgacg aaactggcta aaataagtaa acaggtaacg
     7561 tctattgaat tagacagtca tctattcaac ttatcgtcag aaaaattaaa actgaacatt
     7621 cgtgtcactt taattcacca agatattcta cagtttcaat tccctaacaa acagaggtat
     7681 aaaattgttg ggaatattcc ttaccattta agcacacaaa ttattaaaaa agtggttttt
     7741 gaaagccatg cgtctgacat ctatctgatt gttgaagaag gattctacaa gcgtaccttg
     7801 gatattcacc gaacactagg gttgctcttg cacactcaag tctcgattca gcaattgctt
     7861 aagctgccag cggaatgctt tcatcctaaa ccaaaagtaa acagtgtctt aataaaactt
     7921 acccgccata ccacagatgt tccagataaa tattggaagc tatatacgta ctttgtttca
     7981 aaatgggtca atcgagaata tcgtcaactg tttactaaaa atcagtttca tcaagcaatg
     8041 aaacacgcca aagtaaacaa tttaagtacc gttacttatg agcaagtatt gtctattttt
     8101 aatagttatc tattatttaa cgggaggaaa taattctatg agtcgctttt gtaaattata
     8161 aaagaattgt tttaatgcag gtataaaaga tgaacccgca ccaacaccgc caccaatttt
     8221 agatagcttt gattggtaca tttttagcgc tattcggggt agcgtcagga aaatgcggat
     8281 ttacaacgct aagcctattt tcctgacgaa tccctcgttt ttaacaacgt taagaaagtt
     8341 ttagtggtct taaagaattt aatgagacta ctttctctga gttaaaatgg tattctccta
     8401 gtaaattaat atgttcccaa cctaagggcg acatatggtg taacaaatct tcattaaagc
     8461 tacctgtccg ttttttatat tcaactgctg ttgttaggtg gagagtattc caaatactta
     8521 tagcattgat aattatgttt aaagcactgg ctctttgcaa ttgatgctgt atggtgcgtt
     8581 ctctaagctc accttgtttt ccgaagaaaa tagctcttgc caatccattc atggcttctc
     8641 ctttattcaa tcctctttgt atttttcttc ttaatgattc atccgatata taattcaaaa
     8701 taaagatcgt tttttctatt cggcccatct cacgtaaggc tgtagctaag ctgttttgtc
     8761 ttgaatagga acctagcttc cccataataa gggatgctga aactgttccc tcccttatag
     8821 aatgagctaa tcgcaaaaca tcctcataat tttctttaat gacctttgta tttatttgtc
     8881 cacgtaaaat ggcttctagt tttggatact cacttgcttt atctatcgta aataattttg
     8941 agtccgataa atcccttatt cttggggcaa atttaaatcc taataaatga gtcagtccga
     9001 atatttggtc agtgtaaccg gcagtgtctg tataatgttc ctctatgttt agatccgtct
     9061 catgatgtaa caaaccatcc aaaacatgaa tcgcatctct tgaattagta tgaataatct
     9121 ttgtgtagta agaagagaat tgatcacttg taaatcggta gatggtggct ccttttccag
     9181 ttccataatg tggatttgca tctgcatgta gtgatgaaac acctagctgc attctcatac
     9241 catctgacga agatgttgta ccgtcgcccc aatagaaagg caattgtaat ttatgatgaa
     9301 agtttactaa tatggcttgg gctttattca tggcatcttc atacatgcgc cattgagata
     9361 cattggctag ttgcttatat gtaagtccgg gtgtggcttc ggccatcttg ctcaagccaa
     9421 tattcattcc cattcctaaa agggcagcca tgataatgat tgtttcttcc ttatctggtt
     9481 ttcgattatt ggaagcatga gtgaattgct catgaaatcc tgttatatgg gccacatcca
     9541 tgagtaaatc agttaatttt attcttggta gcatctgata aaggcttgca ctaaattttt
     9601 ttgcttcttc tggaacatct ttttctaagc gtgcaagtga tagctttcct ttttcaagag
     9661 aaaccccatc taacttattg gaattggcag ctaaccactt taacctttca ttaaagctgc
     9721 tggttctctc cgttatataa tcttcgaatg ataaactaac tgataatctc gtattcccct
     9781 tcgattgatt ccatgtatct tccgaaaaca aatattcctc aaaatcccta tattgtctgc
     9841 tgccaacaat ggaaacatct cctgcccgaa catgctcccg aagttctgtt aaaacagcca
     9901 tttcatagta atgacgatta attgttgtac catcatcctc gtataaatgt cttttccatc
     9961 gttttgaaat aaaatccaca ggtgagtcat caggcacttt tcgctttcca gattcgttca
    10021 ttcctcggat aatctcaaca gcttgtaaaa gtggctcatt tgcctttgta gaatgaaatt
    10081 ccaatactct taatagcgtt ggcgtatatt ttcttagtga ataaaaccgt ttttgcagta
    10141 agtctaaata atcatagtcg gcaggacgtg caagttcctg agcctcttct actgaagaga
    10201 caaaggtatt ccattcaata accgattcta aaaccttaaa aacgtctaat ttttcctctc
    10261 ttgctttaat taatgcttgt ccgatgttcg taaagtgtat aactttctca tttagctttt
    10321 taccgttttg tttctggatt tcctcttgag ccttacgacc ttttgataac aaactaagta
    10381 tttgcctatc atgaatttca aacgctttat ccgttagctc ctgagtaagt tgtaataaat
    10441 agatggttaa tatcgaataa cgtttatttt cttgaaagtc acggaatgca tacggctcgt
    10501 atcttgagcc taagcgagac agctgcaaca ggcggttacg gtgcaaatga ctaatttgca
    10561 ctgtttctaa atccattcct cgtatgtatt cgagtcgttc tattattttt agaaaagttt
    10621 cgggtgaagg atgacccggt ggctctttta accaacccaa tatcgtttta ttggattcgg
    10681 atggatgctg cgaggtaata atcccttcaa gcttttcttt ttgctcattt gttagagatt
    10741 tactaaccgt attaaatagc ttcttttcag ccattgccct tgcttcccac accattcttt
    10801 caagtgtagt gatagcaggc agtataattt tgttttttct tagaaaatct atgcattcat
    10861 gcagtagatg aatggcatca ccattttcca aagctaattg atgaaggtac ttaaatgtca
    10921 ttcgatattc actcagggta aaagttacaa agtcgtattc acttcgaatt tctttcaaat
    10981 gatcccaaag tgtattttcc ctttgaggat aatgatcaag cgaggatgga ctaacaccaa
    11041 tctgtttcga tatatattgt atgaccgaat ctgggatgct tttgatatga gtgtatggcc
    11101 aaccgggata ccgaagaaca gctaattgaa cagcaaatcc taaacggttt tcttccctcc
    11161 ttcgcttatt aactatttct aaatcccgtt tggaaaaagt gaagtaggtc cccagtatcc
    11221 attcatcttc agggatttgc ataaaagcct gtctctgttc cggtgtaagc aattctctac
    11281 ctctcgcaat tttcattcag tatcattcca tttctgtatt ttcaatttat tagttcaatt
    11341 atatatcaat agagtgtact ctattgatac aaatgtagta gactgataaa atcatagtta
    11401 agagcgtctc ataagacttg tctcaaaaat gaggtgatat tttgcggaaa atcggttata
    11461 ttcgtgtcag ttcgactaac cagaatcctt caagacaatt tcagcagttg aacgagatcg
    11521 gaatggatat tatatatgaa gagaaagttt caggagcaac aaaggatcgc gagcaacttc
    11581 aaaaagtgtt agacgattta caggaagatg acatcattta tgttacagac ttaactcgaa
    11641 tcactcgtag tacacaagat ctatttgaat taatcgataa catacgagat aaaaaggcaa
    11701 gtttaaaatc actaaaagat acatggcttg atttatcaga agataatcca tacagccaat
    11761 tcttaattac tgtaatggct ggtgttaacc aattagagcg agatcttatt cggatgagac
    11821 aacgtgaagg gattgaattg gctaagaaag aaggaaagtt taaaggtcga ttaaagaagt
    11881 atcataaaaa tcacgcagga atgaattatg cggtaaagct atataaagaa ggaaatatga
    11941 ctgtaaatca aatttgtgaa attactaatg tatctagggc ttcattatac aggaaattat
    12001 cagaagtgaa taattagcca ttctgtattc cgctaatggg caatattttt aaagaagaaa
    12061 aggaaactat aaaatattaa cagcctccta gcgatgccga aaagcccttt gataaaaaaa
    12121 gaatcatcat cttaagaaat tcttagtcat ttattatgta aatgcttata aattcggccc
    12181 tataatctga taaattatta agggcaaact tatgtgaaag ggtgataact atgagcgata
    12241 aaatacttat tgtggatgat gaacatgaaa ttgccgattt ggttgaatta tacttaaaaa
    12301 acgagaatta tacggttttc aaatactata ccgccaaaga agcattggaa tgtatagaca
    12361 agtctgagat tgaccttgcc atattggaca tcatgcttcc cggcacaagc ggccttacta
    12421 tctgtcaaaa aataagggac aagcacacct atccgattat catgctgacc gggaaagata
    12481 cagaggtaga taaaattaca gggttaacaa tcggcgcgga tgattatata acgaagccct
    12541 ttcgcccact ggagttaatt gctcgggtaa aggcccagtt gcgccgatac aaaaaattca
    12601 gtggagtaaa ggagcagaac gaaaatgtta tcgtccactc cggccttgtc attaatgtta
    12661 acacccatga gtgttatctg aacgagaagc agttatccct tactcccacc gagttttcaa
    12721 tactgcgaat cctctgtgaa aacaagggga atgtggttag ctccgagctg ctatttcatg
    12781 agatatgggg cgacgaatat ttcagcaaga gcaacaacac catcaccgtg catatccggc
    12841 atttgcgcga aaaaatgaac gacaccattg ataatccgaa atatataaaa acggtatggg
    12901 gggttggtta taaaattgaa aaataaaaaa aacgactatt ccaaactaga acgaaaactt
    12961 tacatgtata tcgttgcaat tgttgtggta gcaattgtat tcgtgttgta tattcgttca
    13021 atgatccgag ggaaacttgg ggattggatc ttaagtattt tggaaaacaa atatgactta
    13081 aatcacctgg acgcgatgaa attatatcaa tattccatac ggaacaatat agatatcttt
    13141 atttatgtgg cgattgtcat tagtattctt attctatgtc gcgtcatgct ttcaaaattc
    13201 gcaaaatact ttgacgagat aaataccggc attgatgtac ttattcagaa cgaagataaa
    13261 caaattgagc tttctgcgga aatggatgtt atggaacaaa agctcaacac attaaaacgg
    13321 actctggaaa agcgagagca ggatgcaaag ctggccgaac aaagaaaaaa tgacgttgtt
    13381 atgtacttgg cgcacgatat taaaacgccc cttacatcca ttatcggtta tttgagcctg
    13441 cttgacgagg ctccagacat gccggtagat caaaaggcaa agtatgtgca tatcacgttg
    13501 gacaaagcgt atcgactcga acagctaatc gacgagtttt ttgagattac acggtataac
    13561 ctacaaacga taacgctaac aaaaacgcac atagacctat actatatgct ggtgcagatg
    13621 accgatgaat tttatcctca gctttccgca catggaaaac aggcggttat tcacgccccc
    13681 gaggatctga ccgtgtccgg cgaccctgat aaactcgcga gagtctttaa caacattttg
    13741 aaaaacgccg ctgcatacag tgaggataac agcatcattg acattaccgc gggcctctcc
    13801 ggggatgtgg tgtcaatcga attcaagaac actggaagca tcccaaaaga taagctagct
    13861 gccatatttg aaaagttcta taggctggac aatgctcgtt cttccgatac gggtggcgcg
    13921 ggacttggat tggcgattgc aaaagaaatt attgttcagc atggagggca gatttacgcg
    13981 gaaagcaatg ataactatac gacgtttagg gtagagcttc cagcgatgcc agacttggtt
    14041 gataaaagga ggtcctaaga gatgtatata attttttagg aaaatctcaa ggttatcttt
    14101 actttttctt aggaaattaa caatttaata ttaagaaacg gctcgttctt acacggtaga
    14161 cttaataccg taagaacgag ccgttttcgt tcttcagaga aagatttgac aagattacca
    14221 ttggcatccc cgttttattt ggtgcctttc acagaaaggg ttggtcttaa ttatgaataa
    14281 catcggcatt actgtttatg gatgtgagca ggatgaggca gatgcattcc atgctctttc
    14341 gcctcgcttt ggcgttatgg caacgataat taacgccaac gtgtcggaat ccaacgccaa
    14401 atccgcgcct ttcaatcaat gtatcagtgt gggacataaa tcagagattt ccgcctctat
    14461 tcttcttgcg ctgaagagag ccggtgtgaa atatatttct acccgaagca tcggctgcaa
    14521 tcatatagat acaactgctg ctaagagaat gggcatcact gtcgacaatg tggcgtactc
    14581 gccggatagc gttgccgatt atactatgat gctaattctt atggcagtac gcaacgtaaa
    14641 atcgattgtg cgctctgtgg aaaaacatga tttcaggttg gacagcgacc gtggcaaggt
    14701 actcagcgac atgacagttg gtgtggtggg aacgggccag ataggcaaag cggttattga
    14761 gcggctgcga ggatttggat gtaaagtgtt ggcttatagt cgcagccgaa gtatagaggt
    14821 aaactatgta ccgtttgatg agttgctgca aaatagcgat atcgttacgc ttcatgtgcc
    14881 gctcaatacg gatacgcact atattatcag ccacgaacaa atacagagaa tgaagcaagg
    14941 agcatttctt atcaatactg ggcgcggtcc acttgtagat acctatgagt tggttaaagc
    15001 attagaaaac gggaaactgg gcggtgccgc attggatgta ttggaaggag aggaagagtt
    15061 tttctactct gattgcaccc aaaaaccaat tgataatcaa tttttactta aacttcaaag
    15121 aatgcctaac gtgataatca caccgcatac ggcctattat accgagcaag cgttgcgtga
    15181 taccgttgaa aaaaccatta aaaactgttt ggattttgaa aggagacagg agcatgaata
    15241 gaataaaagt tgcaatactg tttgggggtt gctcagagga gcatgacgta tcggtaaaat
    15301 ctgcaataga gatagccgct aacattaata aagaaaaata cgagccgtta tacattggaa
    15361 ttacgaaatc tggtgtatgg aaaatgtgcg aaaaaccttg cgcggaatgg gaaaacgaca
    15421 attgctattc agctgtactc tcgccggata aaaaaatgca cggattactt gttaaaaaga
    15481 accatgaata tgaaatcaac catgttgatg tagcattttc agctttgcat ggcaagtcag
    15541 gtgaagatgg atccatacaa ggtctgtttg aattgtccgg tatccctttt gtaggctgcg
    15601 atattcaaag ctcagcaatt tgtatggaca aatcgttgac atacatcgtt gcgaaaaatg
    15661 ctgggatagc tactcccgcc ttttgggtta ttaataaaga tgataggccg gtggcagcta
    15721 cgtttaccta tcctgttttt gttaagccgg cgcgttcagg ctcatccttc ggtgtgaaaa
    15781 aagtcaatag cgcggacgaa ttggactacg caattgaatc ggcaagacaa tatgacagca
    15841 aaatcttaat tgagcaggct gtttcgggct gtgaggtcgg ttgtgcggta ttgggaaaca
    15901 gtgccgcgtt agttgttggc gaggtggacc aaatcaggct gcagtacgga atctttcgta
    15961 ttcatcagga agtcgagccg gaaaaaggct ctgaaaacgc atttataacc gttcccgcag
    16021 acctttcagc agaggagcga ggacggatac aggaaacggc aaaaaaaata tataaagcgc
    16081 tcggctgtag aggtctagcc cgtgtggata tgtttttaca agataacggc cgcattgtac
    16141 tgaacgaagt caatactctg cccggtttca cgtcatacag tcgttatccc cgtatgatgg
    16201 ccgctgcagg tattgcactt cccgaactga ttgaccgctt gatcgtatta gcgttaaagg
    16261 ggtgataagc atggaaatag gatttacttt tttagatgaa atagtacacg gtgttcgttg
    16321 ggacgctaaa tatgccactt gggataattt caccggaaaa ccggttgacg gttatgaagt
    16381 aaatcgcatt gtagggacat acgagttggc tgaatcgctt ttgaaggcaa aagaactggc
    16441 tgctacccaa gggtacggat tgcttctatg ggacggttac cgtcctaagc gtgctgtaaa
    16501 ctgttttatg caatgggctg cacagccgga aaataacctg acaaaggaaa gttattatcc
    16561 caatattgac cgaactgaga tgatttcaaa aggatacgtg gcttcaaaat caagccatag
    16621 ccgcggcagt gccattgatc ttacgcttta tcgattagac acgggtgagc ttgtaccaat
    16681 ggggagccga tttgatttta tggatgaacg ctctcatcat gcggcaaatg gaatatcatg
    16741 caatgaagcg caaaatcgca gacgtttgcg ctccatcatg gaaaacagtg ggtttgaagc
    16801 atatagcctc gaatggtggc actatgtatt aagagacgaa ccatacccca atagctattt
    16861 tgatttcccc gttaaataaa cttttaaccg ttgcacggac aaactatata agctaactct
    16921 ttcggcagga aacccgacgt atgtaactgg ttcttaggga atttatatat agtagatagt
    16981 attgaagatg taaggcagag cgatattgcg gtcattatct gcgtgcgctg cggcaagata
    17041 gcctgataat aagactgatc gcatagaggg gtggtatttc acaccgccca ttgtcaacag
    17101 gcagttcagc ctcgttaaat tcagcatggg tatcacttat gaaaattcat ctacattggt
    17161 gataatagta aatccagtag ggcgaaataa ttgactgtaa tttacggggc aaaacggcac
    17221 aatctcaaac gagattgtgc cgtttaaggg gaagattcta gaaatatttc atacttccaa
    17281 ctatatagtt aaggaggaga ctgaa
//
LOCUS       DAIGSZ010000062        17152 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.062, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000062 DAIGSZ010000000
VERSION     DAIGSZ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.062"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(734..1912)
                     /locus_tag="NOB31_002186"
                     /pseudo
     CDS             complement(734..1912)
                     /locus_tag="NOB31_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
     gene            1942..2352
                     /locus_tag="NOB31_002187"
     CDS             1942..2352
                     /locus_tag="NOB31_002187"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974376.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            2433..3053
                     /locus_tag="NOB31_002188"
     CDS             2433..3053
                     /locus_tag="NOB31_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974377.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            3754..4038
                     /locus_tag="NOB31_002189"
     CDS             3754..4038
                     /locus_tag="NOB31_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974378.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            4041..4958
                     /locus_tag="NOB31_002190"
     CDS             4041..4958
                     /locus_tag="NOB31_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0974379.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            4951..5733
                     /locus_tag="NOB31_002191"
     CDS             4951..5733
                     /locus_tag="NOB31_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0974380.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            5734..6414
                     /locus_tag="NOB31_002192"
     CDS             5734..6414
                     /locus_tag="NOB31_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0974381.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            6407..7303
                     /locus_tag="NOB31_002193"
     CDS             6407..7303
                     /locus_tag="NOB31_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0974382.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            7498..9147
                     /locus_tag="NOB31_002194"
     CDS             7498..9147
                     /locus_tag="NOB31_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCI0974383.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            9741..10676
                     /locus_tag="NOB31_002195"
     CDS             9741..10676
                     /locus_tag="NOB31_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974384.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            10669..11439
                     /locus_tag="NOB31_002196"
     CDS             10669..11439
                     /locus_tag="NOB31_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0974385.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            11855..12838
                     /locus_tag="NOB31_002197"
     CDS             11855..12838
                     /locus_tag="NOB31_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HCI0974386.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            13285..14322
                     /locus_tag="NOB31_002198"
     CDS             13285..14322
                     /locus_tag="NOB31_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0974387.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(14411..14734)
                     /locus_tag="NOB31_002199"
     CDS             complement(14411..14734)
                     /locus_tag="NOB31_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCI0974388.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(14721..15428)
                     /locus_tag="NOB31_002200"
     CDS             complement(14721..15428)
                     /locus_tag="NOB31_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCI0974389.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            15514..15855
                     /locus_tag="NOB31_002201"
     CDS             15514..15855
                     /locus_tag="NOB31_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HCI0974390.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(16026..16874)
                     /locus_tag="NOB31_002202"
     CDS             complement(16026..16874)
                     /locus_tag="NOB31_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974391.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         5462 a         2916 c         3574 g         5200 t
ORIGIN      
        1 taatgaaaaa cgagaaggaa gatgacttta aagtagttta gtatgaaggt cgattgataa
       61 aacgatgtgg attaatgcta aataatgagt aatttttcaa taatacaaaa actgtgtaca
      121 gtattagaag tagagaaacg ctagcgtcga aaaaaagata tttttcgtga aaagtaatag
      181 gggctaaaaa gaaagtatac aatttattta tgtttctaag catataaaaa agagcgttga
      241 aaggaatatt tccccttcaa cgcttctttt ttagaagatt ttaatgacca tctcaacttc
      301 attttcaggt ttaggtaatt catggaagct tgtgtttatc gtgcttaatt gatcaactaa
      361 ccatgtttta ctttttgact cgtagacaaa tctaaaatta atatcattgt tctcgtgttg
      421 aagaggtttc tccaaataat ctggtgaata ttcatagtca acgtaacctg ctaatacaaa
      481 agaaagcagt ccattattta gtgtcagatt taacggatgg tcgtaagctt ttattttttt
      541 aatgtcatat tgtacatctt atgaagactt aatgactact tgtagtcaat agatttaaag
      601 tatttatttt ctcatttatg tatcaagaat aaatactgat ataataaaaa ttatatcaat
      661 gttttgatga agtaatttgg agggagcgtc aataattttg tgtaaataac tcgtccttct
      721 gcaaaataat gggttactca gtaaacattg aagctaatgt atccgtcact tgttggaagc
      781 ctttatggct tctatttaag aatttttgat tgtatgtatc aaagatggat actaggaaac
      841 gctctagtga ttcttcattt tgaaactgct cttttctgcg gctgtatttc ttgatttgtt
      901 tcttgaaaga ttcgattaaa ttagttgagt aaatgcttcg gcggatacca ggcggaaact
      961 cataaaaagt caataaatct tgatttttta tcagtgactg cgtcacttta ggataagttt
     1021 tttgctactt ctcaatcata ctccctaaaa aggtatttgc ctcttccttt gagctagctt
     1081 gataaacagc cttaaaatca tcacagattt cttttcgatc tttgacacgt actttatgag
     1141 caatattacg ggaaacgtga acacagcaat gttggtattt agctttagga taaatctggt
     1201 gaatcgtatc tttcatgcct tttaagccat cggtaataaa cagtaagaca tcatgaaccc
     1261 ctctggagta aatgtcctgt aacaactcat tccaaacgta ggtcgattca gtcggagcaa
     1321 tcgcataact tagtacttct ttagtgccgt cttctcgtat accaatggca atatagattg
     1381 cttctttgga gacggtttgc cgttttaaag gaatataagt agcatccatg aaaatagcga
     1441 catacttatc atttagagtt ctaactttaa atgcatttac ttcttcagtc agcactttag
     1501 tcatgttgga catggtttgg ggcgtgtagt gatgcccata cattttctca atcaagtctg
     1561 cgatttccga catggtaata ccttttcgga agaggtgaat gacggtctcc tctaagatat
     1621 cattcgtccg tctataagca ggaacagtct gttgcttgaa ctcgccgttg cggtcgcgcg
     1681 gaatctggag atgaagttcc ccgtactcgg tcttgaccgt acggtcatag gagccgttac
     1741 gagaattccc cgtgttaaaa ccaatgcgat cgtacttttc gtaatcgagg aaagccgtta
     1801 actccgtttt gagaagcgta ttgacagctt tttccaaatg gacacggaat aattcattca
     1861 aatcgccttt gttcgctaga gtctttagaa tttctgtagt aaaatcgttc atatggaagt
     1921 cctcttttct gtgaatgtgt tgtggtaact ctattctaca gaagggactt ccttttttct
     1981 atttacacaa aatattttac actctcgtca aatataaaaa ctagtacgaa attaatttgt
     2041 aaattattta agcttgataa aataagcaat atcgatgatg taaagtccaa gatattaaca
     2101 agaaaagtaa gcgaaccagt aaagctaacg gcacaagata aaaaaaatgg aattgttctt
     2161 tatggtgatg atgcaaagta taactataat tgggatacct cctcagaagc tgaggtatta
     2221 agtattccta ctaccgatac ttcaggggaa aaagtcacct ttaaaataaa ttttataacg
     2281 gcaatttcta agttggagta tgggaagcaa aaaaagagag ataacaatga tcaatatcta
     2341 cctaaaaaat aacgaattaa tgatgcatat gttaaagttg tttttttgaa ttaaacaact
     2401 caatttattc agttatatgt tcatcgcagc aagtgaacat taatcgagtt ataaaattaa
     2461 taggagctaa aaatataaat aaagttcgat cagaatttat ttttccagaa gattttttta
     2521 actggttttt ttatcaattc agtgaatgca agcgactctt aggtgagaat tattacttaa
     2581 aaggaatcgg cggatttatg gggaatgtgg ctgatgaaca aaatattata aaaggaatat
     2641 ctgaacaaac atcagagctt acagtaacta aagcatttat aagtaatggt gaaagtttga
     2701 aaaatgtaac tgcgcgaatt agaaaagaaa atgaagtaga cattgttttt ggaattgacc
     2761 atgaatgtaa ttcagtgata tatgtaacac aatcagcaaa tttaattctt tttgagaatg
     2821 gttgcaagga cgattttatg gtggtctatt tgtacgatat actaattcca aaacttcgtt
     2881 ccttatatat gtcttctgaa agtatttttg tgagtgaaca aaagggatct ttctcgaaaa
     2941 aaataggtat tgaagtaatt gaatcgatta tgtgtcataa tcatattacg ctagaagaat
     3001 tagaaatttt gatagggcaa aaaaataata acacgaaaat acaagtttct tagaaatcat
     3061 tttttattga gatatctaga taaatgattt attcttcaat caaccaactc gccaagctga
     3121 ggtaatgttt tgaggtaatg ataacataca actttttata ccctagtaaa actctataaa
     3181 caaagactta ttaatttcgc atgaaataca ttcctgtaaa atgcaataaa atagagtttt
     3241 gtttaaccag gtcttaagaa agcccgtaaa gcttcacagt tctcaaaacg ttaattgcga
     3301 ttatcgttcg agttcacgag ttacgagaat cgtactgggc gaagcaatgc tgagcgcagt
     3361 taccttaatc ctaacttttc tggcactttc cacaatttgg aaagtgcctt ttttgtgttt
     3421 ttagctatgt taataggtag gattcttggt ctataatatc attcgatcta taaacaaacg
     3481 ggaaaaagat aaagtatcat caaacaatat tatttatccg cttctgaggt tgtgacagaa
     3541 gtggtcagct tcaagaaata agaaggaatt tacaaaaatt gcttctcatg tttgataaat
     3601 attgtgactt gtgaccgagg agttggcagg agaacaccgt ttattcggaa gaagggattg
     3661 tgaaaagtct tttgtcataa cctcttattt ggtagctaat tgtaaatccc aaacggcatg
     3721 tattattttt cataagtccg tttttaagga ttaatgtttt cttttgcttt ttatatggtc
     3781 tggcttcagc gagaagttcc aacgcatata caaggacgtc tgatgtcaac gataacaacg
     3841 attaccatgg tggccagtcc acttggatta gcactgtttg gtgcgctctt tgattggcag
     3901 acaactcaac cacgtctgcg agacagtctg atttttcttg aaattcaatt ggaaaattta
     3961 cactttcttt atacatttct ggctgctttc tttatacccg tcaactatac ttcacttatc
     4021 aataagaaag aaggataagt atggattttg gaaatgaaac ggtcttgaaa gcaactggta
     4081 taaccaaaaa atacggtgct gccaaagcat tagataaagt atcgatcgaa atcaaacgtg
     4141 gaatgatcta tggtttgatt ggggagaatg gagcgggtaa gtctaccttt atgagaacta
     4201 ttatgggttt gatctcgatt gatgaaggtt cgatcgaatt atttggaacg acggatttgc
     4261 aggcagcaag acgacgtatg ggtcaatcga ttgaaacccc tgctctttat ccagaattaa
     4321 ctgcaagaga taacctacgt atccaagcag cgaacggcgg tgtgtcggat agagaaatcg
     4381 aagacctgct gaaaatgatg cgattggaaa atacagggaa aaagaaagca aagaatttct
     4441 ctttaggtat gcgccagcgt ttagctattg caaatgcact gatcacgaat ccagaatttt
     4501 tgattttgga tgaaccgacg aatgggatgg atccagcagg gatggcagaa atgcgagaaa
     4561 tcatccaacg tttggtaaaa gaacggggca tcaccgtctt gctttctagc cacttgctag
     4621 atgaattgtc acagatcgcc actcactacg gtattttgca tgaaggacac ttgatcaaag
     4681 aattatcgaa agaagaattg gcacaagaat ctcgtcaatt tataaaaatt gacacttcgg
     4741 cgacggaaca agcagtaacg gttctcgact ctcttggtta tagggattat tttgtccaat
     4801 ctagccgtgt tatccagctt tttgaaggaa ttgaccaagt agcagccatc aatcaagcat
     4861 tggtagaggc aaaagttcct gtggatggta tccacctagt tgggcaaaaa ctggaagatt
     4921 atttcttaca attaactgga ggcaatccac atgtttaatc tattaactgc tgaaaaaata
     4981 aaagtatgga agagccgtaa aatgtgggtc tcactaggac tgatggtcgt acttccgctt
     5041 ttttattctt ggaacgaatg gtatatgcat acaaaatacg gcaatgaatt aaaccaagca
     5101 acggatacag tcatcaacgg tgcaacaggg attttaatgg tggaaaaaat ggctgcatgg
     5161 attcttctgg ctttcgcagc atttgcgtgc ttttatattg gggaagaatt tcaaaacggt
     5221 acgattcgca atacgttatc tttaggacgg aatcgaatga cttattatgt gtcgaaactt
     5281 ctcgttacgc ttttgatcac aacacttggc gtggttttga ttacggggct agccatgatt
     5341 gcttacacac ttgctttcgg atttggtgaa gttgagggaa tcaaaaacta tggaaattat
     5401 gttctaaaag tatttcctgt attgcttctg ctgatattag cgacattatc tgttccagtg
     5461 gctttgacat tcatcactag aagtaccagt gtcagtttgc ttctttcttt tctttatatc
     5521 atgggaacgg ccttcgttcc cggtgttttc gcaaaaatca aaggcttgga atttctaacg
     5581 gagtggttta cggaaacgtg gctcatgtat acggactttg cgcaacaagc aacttattcg
     5641 caagcaccga aaatgattct ggtcagtcta gtaacaatcg tggtatcatc agctctagga
     5701 atgtttattt tccaaaaatc tgacattaag taggtgttcc tgctggaaac tattttgatt
     5761 atcgaagacg atgaagctgt tcattcttta ctggaggagg ttcttgaaca gagatacaaa
     5821 cttcttgatg cttattcagg tacggaagga aaattattgt taagcacata tcctgtcgat
     5881 ttgatccttc tagatctcat gcttccaggg ctttcaggtg aagcattgtt agcagaaatc
     5941 cgacagacat cgaatgttcc gatcatcgtt ctttcagcaa aaagcgatca aagagataaa
     6001 gtttccttgt tggcagcagg agcggatgac tatgtgacga aaccatttga tatcgaagaa
     6061 ctgttgttac gaatcggcat ccaacttcgt catcagactt ctgtccaagt aaaagatctg
     6121 tcgcaacgca tctattacaa ggaaatctta ctggacaaag agtcgaggga tgtaaatgtg
     6181 aatggtgtgg ctgtccattt gacaggaaga gaattcgatc tgctgaagct ttttttagaa
     6241 catccgaaaa aagtattttc gcgagcaaat ctttatgaaa cagtttggca agaaccatat
     6301 tttgatagtg agaaaacagt gaatatgcat atttccaatc ttcgagggaa actagcaaag
     6361 gcacatgctg tgtatattca tacggtgtgg ggagtggggt ttagatttga ttaagtggct
     6421 gttgcttctc gttgttatct ttatgggaag ttttattttc ttcctgcaaa gggaaatcaa
     6481 gagattaact aagaaaatcg ccactctttc tgaacgacaa gaatatggtg gtcgtctttc
     6541 agtcgaattt cgagaaaaga atctaatgga cctagtagat gcactgaata catgggtgga
     6601 tgaaaatgaa caaaaaggac aagcatttca agaaatggaa gaaaacatca gactatcgat
     6661 cgtcggcctt tctcatgatc tcagaactcc tttgactgct attaacggtt atgtacaatt
     6721 actggaacag gtagaggata cggagaaacg ggagaagtat ttaacgatca tcaaacaatc
     6781 tgttgcaaga ttactcagta tgacggatca gttttatgat cttgctcgaa tagagacgaa
     6841 gcaaaaagaa atggatctcc atacgctttc tttttctaaa gaggtggaag aagtattttt
     6901 ctctttttat gaacaatttt ctgagaaaaa tatcgaggta gcgttcgctg aacactcgat
     6961 aaatacaact gtattagcag atccgctcat gttgctgcga gtgctgcaaa atatcataca
     7021 gaatttattg cgttatgcag atggacaagc aaaggtgaca ttttcaaaag aggattcatt
     7081 cattcgatta acagtggcca atcctatcaa accaggagcg caaacctctg ttgaaaaagt
     7141 cttccagcgt ttttataccg aaaataccag ccgcacaaat acggaatcta gcggaatcgg
     7201 gctttacctg tcaaaaaaat tggtggaagg aatgggagga gagatgaccg ctagattaga
     7261 cgggggcatc ttctccatct ccgtcaagtt gcggagggtt taattggctc taatttacct
     7321 gaagtgaatg acaaaaaatt gtatctcgtt ttaaagacat cttctttttt ggaaggtgtt
     7381 tttattttgg tgtgattgat acgaattagg taacgaagac agttattttt gtaccccctt
     7441 ttcaaatagc gcaacagtgc tatactaaaa ctaacaaatc aaggaacgga gagggatatg
     7501 ggccaaagag aatttatcgt tttaattatt attgcagttg ttattttatt agttgtttta
     7561 gacatttttt cacgtttgaa agtaaaggaa acagttcgta gtaattgggg aaaaattcct
     7621 tatcaaccga gatttgataa agaagaaagt ttgaaggatg cgtggctcac ggagaaaaaa
     7681 ttccgttcat gggatagtga aatcgacgat cttacttggt atgacttgga tatgttcgaa
     7741 gtatttgaag ggatcaacag tacctattct agtgtaggtt cagaagcgtt gtatcagcgt
     7801 ttacgtagct ttgattttgg agaagattat cagttagaaa aactaattgc tttttatcag
     7861 gaaaatcctc aactgagaga aagaatccaa tatcaattcg ctcgtttagg aaaaaaagat
     7921 cataattttg caaaacaata tctagcggat ggaaaaagta aaaagattgg acgcgtaggt
     7981 ttatttattt ttcttggctt gcttccgctg gtgggtgtag gtttgcttct tttagggcaa
     8041 gtactaggaa tctatctagc aatcggtggc ttagtattca atacggtcta ttatctagtg
     8101 aagaaacaaa cactagaaac agagctgaat agcatgagtt atttggtttc aacgatttca
     8161 gccgccaatc agttagcaaa aatgacgaca ccacttcaaa aagagctgaa acagcaaact
     8221 aaaccattaa gagacatccc taaattaggt ttttcatttc gaatgaagag cgggagtgaa
     8281 gcagaattga tttttgaata tgtcaacatc atgttcatgc tgccatttat ctcctatcat
     8341 ttcgttctca ctaaattaga aaagcattca actgaagcca tcaagctgtg ggaattgctg
     8401 ggagaattgg aagttgcagc agccgttttg aattatcgca cctatatgcc gatcacttgc
     8461 cgaccagagt ttactgaggg cggtgtgaca gcgaaagata tctatcatcc attgttaaaa
     8521 gaagcggtag ttaatccagt caactggcag aagaatacat tagtcacggg ttccaatgca
     8581 tcaggaaaat ctacgtatgt caaaagtata gccatcagct gtattctagc acagacgatc
     8641 caaacagcga ttgcagaaca gtttaccctg caacctggac atgtgttgac ttccatggca
     8701 atcgaagatg atttatttga aggcgacagt tattttgttt cagaaatcaa atcgatcaaa
     8761 cgtttgctgg accaagtggc ttccaaagaa cgctgctact gcttcgtaga tgagatttta
     8821 aaaggaacaa atacgatcga acggattgct tcttccgctt cagtcgttcg gtggcttgcg
     8881 gagtatccat ctttagcatt tgtcgccaca catgatatcg aattgacaga gattttaaag
     8941 aattattgtg agaatgtcca ctttgaagaa caagtaacag aaggaaaagg aatcagtttt
     9001 gatttcaaat taaaagaagg accttcaagg acccgaaatg cgattgcctt gctgaaagtt
     9061 ttgaattatc ctaaatccat agttgaacag gcccaaaaag aaagtttgtt gttcgatgaa
     9121 cagcgtcagt ggtatccgtt tgattaactt tatcaaacga agcatgatgc gtgggtccaa
     9181 aaagacgatt atcaaaagaa gtacattgat gccaaaaaag tggcagaatt caatgggaac
     9241 gagtctgctg tccagatgat cttggaagat ttagcaaaag acgatacaaa ataaaccacg
     9301 ctgtcttcct tctagcagct tttatcgaaa aaacttagca tcagcgacga gacgcacgtt
     9361 ccatggcaaa gttctccgta aaacaaacag cgaaaacaga aattgaaaat aactatttcc
     9421 attttattta tttcggttaa aataaaagaa aaaagctttc gataaaagga cggaggaaag
     9481 cttaacatga ataaaaaaga caagaacctc agttataagg atcttctata tgtcatcgta
     9541 gtagttgctg tcggtacttt tatgatttta aaagttccag agttgtttag atagttattc
     9601 tatcgaagat gatcatgaac tagaaaacac atctcctctt tgttagcagg tgtgtttttg
     9661 tgtggaagcc aagttgtttt ttcatctgct gtattccatg atacaattaa gaatcatgtc
     9721 tataaggaga taggaaataa atggcaaatg cgcttgaaat aaataatttg aaaaagatct
     9781 atggaagtgg ggtcgaagca ttgcggggaa tcgatctttc ggtgaaagaa ggagatttct
     9841 atgcgctatt agggccaaat ggagctggga agtctacaac gatcgggatt attacttctt
     9901 tagtcaataa aacatctgga aaagtgaatg tcttcggtta tgatctggac aaggatctag
     9961 ttcgagcaaa gcaacagatt ggattggttc cacaagagtt caattttaac ccttttgaaa
    10021 cggtccagca aatcgtcgtg aatcaagcag gctactacgg tgtctctcgc aaagaagcga
    10081 tgaaacgcag cgaaaaatat ttgaagcagt ccaatctttg ggaaaagaga aatgtccgtg
    10141 cacgtatgct ttccggggga atgaagcgaa gactgatgat tgctagggca ttgatgcatg
    10201 aaccacgttt gctgatcttg gatgaaccaa cagcaggagt tgacatcgag ttgagacgcg
    10261 agatgtggga gtttctacga gaattgaacg aaaatggtac aacgatcatt ttgacgacgc
    10321 attatctaga agaagctgaa atgctttgtc gcaacatcgg aatcatccaa tcgggtgaac
    10381 tgatcgagaa tacaagtatg aaagagcttc tgtcaaaact gcaatttgaa acatttatct
    10441 ttgatttagc gccatatgat accaaacctg tgattgaagg atatgcttgt acatttgaag
    10501 atgagcagac aatcgctgtc gaagttgaac gaaatcaagg ggtgaacgga atcttcgatc
    10561 agcttacaag acaaggaatc aaagttcttt ctatgaggaa taagtcgaat cgtttagaag
    10621 aactgttctt gaaaatcaca gaagaaaata atcatacgga ggagaaaaat gtttaatctt
    10681 tattttactg cattaaaaag tttagctatc aaggaaacga accgctattt gcgtatatgg
    10741 gtccaaacac tggttccgcc agtgatcacg acatccttgt attttgttat tttcggaaaa
    10801 atgatcggtg ggcggatcgg tgacatgggt ggtttttcat atatggaatt catcgttcct
    10861 ggtttgatta tgatgtctgc tatcactagt tcgtatgcca atgtttcttc gtccttcttc
    10921 tctcaaaaat ttcagaaaaa tatcgaagaa atcttggtag cacctgttcc tacgcatgtg
    10981 attatttggg gctttgtgat tggtggtgtg ggtcgcagta ttctcgtcgg ctctctcgta
    11041 acgatcattt ccttgttctt tgtaccactt catgtgtatt catggttcat ggtcatcatt
    11101 acattattga tgacggcaat cttgttttca ttagcaggac tgctcaacgg gatttttgct
    11161 cagtcttatg atgatgtatc gatcgtgcct acatttgtct tgcagccgtt aacttatcta
    11221 ggtggcgttt tctatgccat ctctatgtta ccgccctttt ggcaagctgt ttcaaaagtc
    11281 aatccgatcg tttatatgat ctccggtttc cgttacggat tccttggaac gatcgatgtg
    11341 ccagtagcaa catcgatgat cgtacttgtg ttattcatcg ttgttttgta cgccgttact
    11401 tggtatttga tcaataaagg aagaggattg agaagttaga aaagaggttg tgaaatcagc
    11461 gttttgacct gagtattaga gaaacaaacg ggaaaatagt tcctcatatt ttgttgtttt
    11521 ttgagcgaat accgagggtc agctgattga acaccgttta gtggagaggt tgtgaaaaag
    11581 ctgttctgca tcaagtaata agaacagcca aacaaaaata gctcctccta tttttcgttt
    11641 ggttggactt attaccgcag atgcaagctt ttgaacacca tttattccgg aaaatggact
    11701 gtgataagat ttttgtcaca gtcttttttt tgctcaatca gaaacatctt ttaagctgtt
    11761 cactttgctt ctttttttgt ttcctagtat aatgacaatg tttttgagaa agattgcgac
    11821 ttcactgctt gatagaatgg agagtaacaa ataaatgact actaattttt ggaaagagct
    11881 gccaaagcct ttttttgttt tagcaccaat ggaagatgta acagatgttg tatttcgcca
    11941 tgtcgtaaag catgcagcag caccggatgt cttctttact gagtttacaa actcagacag
    12001 tttctgtcat ccagatggaa aagacagtgt acgaggaaga ttaacattta cagaagatga
    12061 acagccgatg gttgcccata tttggggaga caagccagaa ttttttagag aaatgagcat
    12121 tgctatggca gaaatgggct tccaaggaat cgatatcaac atgggctgcc cagtccctaa
    12181 tgtagcagaa cgtggaaaag gcagtggctt gatccttcgt ccagaagtag cggcacaatt
    12241 gattgaagca gctaaagctg gcggtttgcc tgtcagcgtc aagacgcgta tcggctatac
    12301 ggaaatgtct gagatggaag aatggatcag tcacctactt catcaagata tagccaatct
    12361 ttctgtccat ttgcgtacgc gtaaagagat gagtaaagta gatgcacatt gggaagtcat
    12421 tcctaaaatc attgctttac gtgaccaaat cgctccacaa acactaatca cgatcaatgg
    12481 agatatcccc gatcgccaga caggagaaga attggccgag aaatatggcg ttgatggcat
    12541 catgattggc cgagggattt tcaagaatcc ttatgcattt gaaaaagacc cgagggaaca
    12601 tacagaaaaa gaactgatcg gactacttcg tctgcaacta gatctgcaag atcattattc
    12661 agaaatcatc ccgcgttcca tcacaggact acatcgtttc tttaaaatct atatcaaagg
    12721 atttccagga gcaaatgact tgcgagttca gttgatgaat acgaaatcta ctgatgaagt
    12781 acgagagatc ttagagacct ttgaaaaaga acatccaacg cttttcagtg aacaatgatt
    12841 tcttgcttga acaccgtgaa ttagaggtcg tgaaaaagct gtcctgtatc aagtaataag
    12901 aacagccaaa caaaaatagc tcttcatatt ttgtcgtttt ttgagctaat accgagggtc
    12961 agttgattga acaccgttta tatcagaggt tgtgagcctg ccgtttaact ctgagtcaca
    13021 aggagcaatt tcaaaaaaca gcttctcatg tttgatgaat attttgactt gtgaccgaag
    13081 agttggtagg agaacaccgt ttataagagg ttgtgacaaa agtcttgtcg caacctcttt
    13141 tttaaccaaa aaagtgcaaa tagtttactt taagtaagag aataattatg atgaataaaa
    13201 aaggtggaac aaatagcata ctatatatat tgaaatgaac actgtatgga tgctccaact
    13261 tgatgaagct aaggaggaat tcgtatgtca gaaaaggaat taatgaaggt agtcggtttt
    13321 tatgaagggt tgccgatcga tgatccaaaa agctttattg atgaaaaaga acagatacct
    13381 gtacccagtt cacgggatct tctggtaaaa gtcaacgcag tatctgttaa tcctgtcgat
    13441 acgaaacttc gccaagataa cgggataaga aatgctttac gtatcttagg ttttgatgga
    13501 gtcgggaaag ttgttgctgt aggtgacgaa gtgcaaaaat tttctgtcgg cgatcgcgtt
    13561 ttttacgcag gtacaacaac aagagcagga agcaatcaag aataccaact agttgacgaa
    13621 cgtattgtcg ctcttgcacc aaaaaatctt tcagatgaag aagctgcagc cttgccgttg
    13681 acctcattga ccgcttatga attgttattt gaaaaatttg gtctaactcc agaagaaaat
    13741 gccaatcgcg ggaaaaaaat cttagtgatc aacggatccg ggggcgtcgg ttcgattttg
    13801 aatcaactag cgcattgggc tggcctagaa gtctacgcga ctgcaagtcc gaagaatttt
    13861 gaatggctga aaaaaacagg tgtagactat ccaatcgatt atcatcacga cttaagtaaa
    13921 agttttcgtg aattaggaat cgatcaagta gagtatgtcg ctgtattatt cgatattacc
    13981 cgctactttg atcaaatcaa gcaccttgtc cgaccatttg gacatgtggg aacgatcgta
    14041 gggatcaaag agccgttaga tataggtgtt tggaaaaacc aatctatcag cttcgactgg
    14101 gagtatatgt tcgctaaaac agactataac tatgaaatcg aaacgcaagg agaagcttta
    14161 gcgcacattg ctgctttagc aaatgaaggg attatccgca gtacattgag caaggtctat
    14221 tcagatggga tgaatgcgaa gaacttgaaa caagcaacca aagacgtaga aacaggacat
    14281 atgttaggaa aagtcgttgt tagtggtccg ttcaacggat aagcaagaat acgccgattt
    14341 ttttcttatt tgactttgat aaaaacaaga gcgcatgaca gtaatttgcc ataagctctt
    14401 gtttttttat ttataataag cgaatcaacg aaagggaaag aattcctgcc aagacgatca
    14461 ccaataagct ttttgaaaga atagcagcta aaagtgtagg aactgaagcc aaagcatttt
    14521 cgagattgat ctgcggcaga tgtccgatat tttgggtaaa tagactgctg aaccataaag
    14581 cagacataat gacgatcggg acaaaactta aatactcaag caacggttgc ggtaaatcga
    14641 attttttcag taagacaaat ggtaggaccc tagaaagcca agttgctaaa gtacaaccta
    14701 aaatagtcag caatgtaaac tcaaaagaag gcatgtttga tccacacccc caatccgcac
    14761 ccaatcagtg ttacaactac aatcactaag ttgcttggga taaaaatcag tccgacatat
    14821 accagaatca aagtgagacc aatcaggatc aactgtaatc gtttagaggt gtttctatca
    14881 gaaatgactt gaagataaag taacccgata aacatagcga cgatggcgaa atccaaacca
    14941 aactttttcg gatcagtaat aaaattccct aaaagtgcgc caacaagaga agaacccacc
    15001 cacgtcaaat aagaaatcca attagctgta ttcatccaac gaaagtttaa cttttgtcca
    15061 gtatagttca atttattcat tcccagtgcg aaactttcat ctgtcagcaa tgtgccaatc
    15121 agcagatttt gaagcagccg atttttcttg aaataaggag caatcgtcat actcatcaga
    15181 atcattcggg aattgactag aaaggtcgag aaaacgatgg aaagcaatgg gctgtgacta
    15241 gcaagcatgc tgactgtgat aaattgggca gaaccagcat agaccagcag ggacatcaac
    15301 gtgacgacta gtggatgaaa tccggcagct ttcccaacga taccaaatgc aagtccaata
    15361 ccgatataac cgaaaacggt aggtaacgtg tctttgatcg cagtttttat atctaacttt
    15421 tcatccaata acaaaactcc tttagcacga cataaatttt cataattgtc gttaaacttg
    15481 tgaatattct aaatttttaa tgagcatttg tcaatggtgg gattgaaacg taaagaacta
    15541 gcgggtcgca gatttacacg tattgtttcg gtgggaggag gcgcgaaaaa tcttgcatgg
    15601 ctacaaatcc aagctgatat tttcgatgca acggtctatt gtttaagtgt ggaggaagga
    15661 cctgcattag gcgcaacaat gattgctgca ctagggttag ggtggttcga cacacctgaa
    15721 agttgttgtc agaattttat ccaatataca gatgcagtgg aacctctctt acaaaatgta
    15781 gaaaagtatc ataaaatcta tcaacaatgc cggaaaatct atccagcaac gaaggaaatt
    15841 tgtcatgact tataaaacaa aacgcgtacc taatagtcaa atgactaata ttgggtacgc
    15901 gttaagtctt ctttacttca tcctttgcat gattcgtgtt tttaaagcaa ggtctgctgt
    15961 atttcttgtg gatttaggat ggttgttatc gtttacttgc tatttttcat tgaaatcgtc
    16021 tttctttacc gtttctttag ttttttatct atttttttct tttggttaga aaattctttt
    16081 tcccgaaagt cttctttcag gatttttata gagtagcgtt ttgaataaga ggcgtcagta
    16141 tgatcgactt ggcagacgaa ccaagagaac atttgccttt tttctgcatg aggtgcttct
    16201 gctaataatt ctttccataa ataataacag tcctctatca gaagaagggt tcgttcatcc
    16261 tcaggctccc aatagaatgt ttcgagagta gcaatcactt cattgatcaa ttcgaatgcg
    16321 ggaagatagg cattttgctg aataagcgat tcaactgctt cttggatgaa ctttcgcatc
    16381 tccatgatga acttcgctgt tttcctgttt ttgtttttct tgataatatg atcgtattta
    16441 tggatgatag ttgttaattt atctgaataa tttattgcat gaaatggcat cttaactttg
    16501 aagcgttcga taaagtgcgg atgttctata agaatctctg ttaaaagctc ccgtacaaga
    16561 gaggaactag cggaggaaac aagggacgag agttcggaaa gtgagtagtt ggattttttt
    16621 attggacgtt cttcgtaagc gaataagaca gcagccatgt gtttgcattt ttttccttct
    16681 atggcatata gacaatcaca agtcatgttg gtcttttcat cccaagtgat cactacctta
    16741 taatcttccg tgccagaaac tgttgcggac aagtacttgc ttgtatagtt caaatgacgg
    16801 acaaaaccgt gcagatgata gctgtaaccg cgttccaaaa cgttttcagg aaaatactca
    16861 agccaattat tcatctagtt ctcctttcat gaaacactta tttatattta gtataaagaa
    16921 acgtttaaga aaaaagtagc tgattttaca tatttgataa tcacttttgc tcgaattgtc
    16981 aaaaattcat tctccttttc ttttcttaga gaatgtgaga aaaagtaaaa gaatagcgtg
    17041 ttttaaagat ggaacttttt ttgtttttta tttatctgac aaaaatgaag tgattttgtt
    17101 agaaataaat aattgttcca attgataaaa gaggtatgat gtatcgcaaa ga
//
LOCUS       DAIGSZ010000063        17006 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.063, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000063 DAIGSZ010000000
VERSION     DAIGSZ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.063"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..125)
                     /locus_tag="NOB31_002203"
     CDS             complement(<1..125)
                     /locus_tag="NOB31_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HCI0974392.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(229..540)
                     /locus_tag="NOB31_002204"
     CDS             complement(229..540)
                     /locus_tag="NOB31_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCI0974393.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(542..739)
                     /locus_tag="NOB31_002205"
     CDS             complement(542..739)
                     /locus_tag="NOB31_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HCI0974394.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1133..2860)
                     /locus_tag="NOB31_002206"
     CDS             complement(1133..2860)
                     /locus_tag="NOB31_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HCI0974395.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2853..4046)
                     /locus_tag="NOB31_002207"
     CDS             complement(2853..4046)
                     /locus_tag="NOB31_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HCI0974396.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4233..4877)
                     /locus_tag="NOB31_002208"
     CDS             complement(4233..4877)
                     /locus_tag="NOB31_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0974397.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4971..5105)
                     /locus_tag="NOB31_002209"
     CDS             complement(4971..5105)
                     /locus_tag="NOB31_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HCI0974398.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="NOB31_002210"
     CDS             complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="NOB31_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HCI0974399.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7236..7709)
                     /locus_tag="NOB31_002211"
     CDS             complement(7236..7709)
                     /locus_tag="NOB31_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HCI0974400.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8110..8334
                     /gene="nrdH"
                     /locus_tag="NOB31_002212"
     CDS             8110..8334
                     /gene="nrdH"
                     /locus_tag="NOB31_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HCI0974401.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8493..10652
                     /gene="nrdE"
                     /locus_tag="NOB31_002213"
     CDS             8493..10652
                     /gene="nrdE"
                     /locus_tag="NOB31_002213"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HCI0974402.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITTEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10702..11667
                     /gene="nrdF"
                     /locus_tag="NOB31_002214"
     CDS             10702..11667
                     /gene="nrdF"
                     /locus_tag="NOB31_002214"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HCI0974403.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11756..12895)
                     /locus_tag="NOB31_002215"
     CDS             complement(11756..12895)
                     /locus_tag="NOB31_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCI0974404.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13204..13917)
                     /locus_tag="NOB31_002216"
     CDS             complement(13204..13917)
                     /locus_tag="NOB31_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HCI0974405.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="NOB31_002217"
     CDS             complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="NOB31_002217"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HCI0974406.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15106..16638
                     /locus_tag="NOB31_002218"
     CDS             15106..16638
                     /locus_tag="NOB31_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCI0974407.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16829..>17006)
                     /locus_tag="NOB31_002219"
     CDS             complement(16829..>17006)
                     /locus_tag="NOB31_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0974408.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5279 a         3495 c         2909 g         5323 t
ORIGIN      
        1 gaaaaaacac attccactaa atttgatgcc ggttttcctt gaggttttgt tccagcacct
       61 cctttaattt ttttaagctc ttgatctgaa cattgtttag catttagtct atttttttct
      121 tccattacga ttccccctac aaactataaa tacttttatg tcactgattc aatataccta
      181 tttttctaat caaaaaattt tgagacatat ttaatattat aagtatcatt aaaattgaga
      241 tttatctcca taatctgctc gatataaacc atttattcca gcagttcttc caatttcact
      301 caaatttctt attaattcct cttgatattc agtgaatctt attttattag tataagcagt
      361 aaaatataga taattcacca atctatttat taaaggactg ggatctaatt catatttttg
      421 tttttctaat tttaaatata ccttttgtaa aacctcaaga atatcagaat atttaggatc
      481 tttacttata gatatatcat tatataattc atgaacaatt tgcttagcat tttttttcat
      541 tttagcactt ccctggaatt gctccaccta aaaaaccacc tatagacatt cctgcaatac
      601 aagtagttgc cttggcccaa tcgaccgtac atttattttt agtgcaatac actccatttc
      661 cataatattt tccactatga gtggtacccc catagataag ttgtgtctct ttaatagaca
      721 aaatttttaa atgtttcata atctaatcac ccctaaatta atgtttttag actattattc
      781 taacattcat taaatttcaa aaaacaattc cttcttgaaa cgtagcaaaa taattcctga
      841 ataagaattt aatcactttt aagtatataa actatgtata ttctttaata ttttttgaga
      901 atgcacttcg tacataataa actttaatca cattagtctt tcatacctac gatcgatctc
      961 tttgactcgc acccataaat tcataatagt ttgtcggcgt ctttgaacgt ttcgaagatg
     1021 agctacgcat tctctttttt tatagacaaa aaagatagag acgaacatgg agcttccaaa
     1081 tttggatatt tgatccaatt ttggaagctc catttatttc gtgtctgtct ttttattttt
     1141 tccagctttc gactaattct tggttctctt tgatccagtc ttttgctgct tgctgtggat
     1201 cttttccatt gttgatttcc aacataactt tttccatatc tttttctgac caatggaaat
     1261 tgtctaatac tttgtaagct tctggctggt cttctttcaa tccttttcga accatcgtat
     1321 ggatctgctc ttcgcttccc attccgtttt caggatcttc taagtatttc agatcatatt
     1381 tggcaaacat ccaatgaggt gtccatcctg taactacaat tggttcgtgt tttttgatcg
     1441 cttgacctag tgcaacggtc attgctcctg aagaagatgt ctctactttc cagtctttca
     1501 agttgtcata tttttggatc gtgttttcag cagccgtaac tacaccagct cctggctcga
     1561 ttcctatgat tttcttacct gcctgatcgg ttaactcatc gatcgaattt acatccatgt
     1621 aggctggcac tgctaaacca acttttgctc ctgtcaaatt ggcacctagg tcttcgactt
     1681 gatctttata ttgtgcatat tgtgaaccat gagttttagg tagccaagct gaaaccatgg
     1741 catctgactc gccatttgaa acagatttcc acatgattga attatctaat ggcgtcatcg
     1801 ttacatcata gcccatttgt ttcaatactt caccgactac atttgttgaa gcaacttctg
     1861 tatcccattc aacataagat aagttgatac gttttgtttc tttggcagat gaaaaactcc
     1921 ctataccaat cgcacctaag atcactacta ctacagcacc aatgatcagt ccttgacgtt
     1981 ttttactttt ctgtgttgtt gctcctgcag cttttttatt gtttggctgg ttcaaatgct
     2041 gtgtaaaacg gtcaatgatg attgctaaga taactaatgc aaccccgttg acaaatccat
     2101 tcccgacttg tgctctttgc aatgctgata atacgccgcg tcctaagccg ggtgcaccga
     2161 tcatagaggc aataacgacc attgaaagtg acagcattgt tgtttgattg atccctgcca
     2221 tgatcgtact tttagctaaa ggcaattcta gtttgaatag tttttgacga cttgtgctcc
     2281 cgaatgaatc agaagcttct actaattctt taggaacttg tcgaatccct aaattcgtaa
     2341 aacgaacggt tggtggcaga gcaaagatga ctgaggcaaa tacccctgga accatcccga
     2401 taccgaaaaa tgcaactgct ggaatcaaat aaacgaatcc tggcattgtc tgcataaagt
     2461 caaggatcgg tttgataata ctttgggctt tactgctttt tgccatcaag atccctaatg
     2521 gtaccccaat gatgatcgag atcacactag ataaaagaac aagtgtgaca gtattcatca
     2581 aatcattcca tagaccttgg ttataaataa accatagacc gattaatgtg aacaacgtaa
     2641 gtcctggacg tttcttagaa ataaagaaag ctgctaccgt caataacaag ataaacaaag
     2701 gagctggaat cactaacagt aaatttgtaa tccccgacat cactgcctgt ccaatcgttt
     2761 gtaaaaatga aaataggcca gaaaaagttg tcgtaaacca ttctgtgata ttttctaccc
     2821 agtttgccac tggtaattga tagttcaata gattattcat gttcactcac ctcgcttgtt
     2881 tctgctaatg cttcaatcac actacctcgg atgacgacac cttttaattt tccatcctct
     2941 acaactgcaa gtggagtcgg tgagtcataa ataatattga aaatatcact taccaccatg
     3001 tctttcccaa tcaccgtcac attttcatct aggaagtcga tcaatggacg tttttgcttc
     3061 ctagcttcta acgcttgatc tgcagtgatg atccctttca ggtgtctctt tctgtcaaca
     3121 gccatcagca tgctgacttc ttcattacgc atccttgtca atgcaacgtt tggtccatca
     3181 gattcgatat tcgtcgtcaa tgcaggtacc atgatgtttt gagccgtaag cactttggaa
     3241 cgatcgactt cttccacaaa ttcacgtaca taatcatttg ctggattggt caatatttct
     3301 tcacctgttc cgatctgcat gatttcgccg tctttcatca aggcgattct gtccccaatc
     3361 cgtaaagctt cattcaaatc atgggtaatg aaaataatcg ttttttgaac attggcttgc
     3421 aggtccagta attcgtcttg catttctcgc cggatcagcg gatcaagagc cgagaacgct
     3481 tcgtccatca gcaagatctc aggatcattt gctaaagctc tggctaggcc aacccgttgt
     3541 tgcatcccac cagataactg actaggatat tggtctttaa atgaaagcaa actagaattt
     3601 tctaatgctt tttctgcttt ttcttgtcgt tcttctttag gtacaccacg gacttctaac
     3661 ccgtattctg tattttccaa gatcgttcga tgtggaaaca gaccgaagtt ttggaaaacc
     3721 atattgattt tatgacgacg gacttctcgc aattcttctt tgcttaactt cgatacatct
     3781 tctccatcaa tatagatact gcccgaagtt ggctcaatca gacgattcaa tagacggatc
     3841 aatgtggatt tcccactccc ggaaagcccc atgatcacga agatttctcc ttcttttacg
     3901 tcaaaattca cgtcatacac accaaccgtt gcaccggttt tctttaaaat ctccgttttc
     3961 ggctggtgat cattcatcat atctaaagcg gcttgtgtct ttttaccaaa tatctttgtt
     4021 aaatgtttta cttctacttt taccaaacaa attctccttt tttatgtaaa ttcatttttc
     4081 tttctgaaaa aagtgaccac actatgttaa catcatgtag tcactttgtc aaaaatgaaa
     4141 gaaatttgct tgtccaaact gaaaaaaact tggctaaatc tttgtaaata aaaggtttag
     4201 ccaagttaat atttttttaa tatttcacac aatcattctg caagctgatg ctccgggtaa
     4261 aaaaagtttg tcatacgctg tagtgtatat tcatttccaa taaaatgaac gatgtcccct
     4321 gccgtaaatt tagcataggg gccaggtgaa acaagcagtt cttcattatg agaaattgcg
     4381 ataactgtgg cgccagtcgc ctgccagata ttcaactcgc taattgaacg gtccagatgc
     4441 attgcttttt ctgataaaga taattcaaac ggaagtaaag gattcatctt atgtattcgc
     4501 ttcgtttgat tgaccagctg atccaataat tgagaaaaat gattcagctc atcttgttgc
     4561 ttctccacac ttgccatgat ttctgctttt gtatcttgga tggattgtac atcttgatat
     4621 tgcaatagga aatcttttgc tttttccttc gaagcaacaa atgccccact tccatgccgt
     4681 acttccatga ttccaagatc taccagcaca ttgatagcct tgcgggtagt ctcaggagaa
     4741 gcattgtacg tactggcaag tgttgagcgg gcatggatct tctcacccac tttatatcgg
     4801 ttttcaacga tacgttcggc taaatcaaca gcaatctgct ggtagcgcgg gcggacgatt
     4861 tttttctttc cagacatttt ctttcctctt tcttttttta ctttccctca tcttactatg
     4921 ctctagcaaa ataagcaaaa aaggggagaa tagcctcttg caacgactga tcatcgcttg
     4981 atctgttcct tttttactgg gcaagctgtt tgacagtcat cacaattctt accggatttt
     5041 aaacgagtat agacaattgc gcctgcactt ccaaagatta acacacttaa taagaatgtc
     5101 gccatcctat tcctctcctt ctaatgacaa tatagtataa aactggttct tggattttgg
     5161 ctgacggaac aaaacataaa cgagtcctat catcagtaaa atagcaagat acgtccctaa
     5221 cgctacctgt ccaccctcca ataagtgtcc caactgataa atcacaaaac taactaaata
     5281 agctaaaccg cattgatagc ctatggcgat ccaagtccat ttcttggcat tcatttcccg
     5341 atggatagcc ccaattgccg caaaacaagg cgcacaaagt aaattgaagg ctaacaatga
     5401 ataagctgct gcgggagtat atgtgtgttg tagcacttgc cagatttctc tgccattttc
     5461 ggatacttcc gcatgaccaa acaaaatacc aaatgtgcca ataatatttt ctttagcgac
     5521 caatcctgta atcgctgcga ctgttccttg ccagtttccc caaccaagcg gctgaaaaac
     5581 aactgccagg attcgcccga aaaaggctaa gatactttgg tcttcagaaa caggttgagc
     5641 ataaaaatta taagaagagc tgaaccagat cacgatacta gaaacaaaga taatcgttcc
     5701 tgctttttta acaaaagact tgctgcggtc ataggtttgt cttaggaccg ctgaccattg
     5761 aggaaaatga tatgcgggca attccatgat aaaaggagct gtatctccag caaacaaacg
     5821 tgtttttttc aagctgattc cagagaaaat aattgcagtc ataccaagaa aataggcaga
     5881 aggagctacc caagattgat gaggaaaaaa ggcccctgct actaaggcaa taatcggcaa
     5941 ctttgcagaa caaggcatga aggttgtgac catgatcgtc aaacgacgat cttgctcgtt
     6001 ttcaatcgtg cgactggcca tgacgcctgg cactccacat cctgtagcaa tcagcatagg
     6061 aatgaaggat tttcctgaaa gaccgaattt cctgaaaagt cgatccatga caaaagcgat
     6121 cctcgccata tatccgcagt cttccagaaa gctcaagcat aaaaacaata taatcaattg
     6181 cggtagaaat cctaacactg ctcccacgcc tgcgatgatg ccgttcaaga tcagctcctg
     6241 catccatccc gctacttgcc attcagctaa caatctgcca acatgttctg gtaaccatgt
     6301 accaaacaat gtgtcattga tccaatctgt ccccattgtt cctactgttt gaatagccag
     6361 ataatagatc agccacatca caaatgcgaa gatcggcaag gctaaccaac gattcgttgc
     6421 aatctgatcg attttgtcac tcatcgataa ttggaaagaa tcatttgaca caacacagag
     6481 tgtacatagt tgggtaataa attcataacg ttcattgacc agaatcgtct cactatcgtc
     6541 gtccaatagt ttctctgtta actggatcag ttgctcgatc tctttttgct gagaaactgc
     6601 tatctcgtaa tcctctctta ccttctgatc tcgttcaaaa tatttcattg cataccagcg
     6661 tttcttgccg ctttgttctc ctagtacatc ttcaatttca tgtaaagctg cttctaaacg
     6721 tggatcatat gtacagggaa caggaataga aggccgcttt tttgcagact cctgaatctt
     6781 ttcgattagt ttttcgattc cttgcttttt caatacgctg attggtaaaa ctggtacacc
     6841 aagaccatag gaaagctttt ctagattgat tttttttcct tcttttttga tgacatccat
     6901 catattcaga ccaatgatca taggaatgtc taaatccaat aactgcgtag ttaaataaag
     6961 atttcgttct aaattggtag catcaataat gttgatgatc agttcaggct gttcctgaac
     7021 caaataatct cttgcaatca cttcttctgg tgtataagga gacaaagaat agatgccggg
     7081 taggtcctga atatgaatgt tcggattttt tttcaacgat ccttcttttt tttctactgt
     7141 tacgcccggc caattcccta catattgatt cgaaccagtc aagagattga acaagctagt
     7201 tttcccgctg tttggatttc cgactaacgc gatattcatt ctttttcctc cctttgtatc
     7261 aagattagtt cggcctctga ctttcgtaac gtcagttcat accctcgcac tgtcagttcg
     7321 attggatctc ccagaggggc tagttttcgg ataactattt ttacatttcg cgtcaatccc
     7381 atatccatta accgtcgctt cactgcgcct tgtccgtgga ttgctacgac gatcccagtc
     7441 tctcctgctt ttaattgatc aagagaagtc cagctttcag aggaagcagt ctttttattg
     7501 acaaagattt gacctagtat ttcccgactt actgccactc gatgactttt taccagtaaa
     7561 atggcattgt tgcctgataa attgacgacg acgattttac ttccggcaac gatcccgata
     7621 ttttgcaaat ggcgttttgt tttttcttct gtttcgattc gttcgacttg ataaacgaaa
     7681 ttctgctttg cctgcgctaa ggtctgcata ttgattcctc tcttgtgaaa taaatcatgt
     7741 attaaaatca ttcattatat gttctaattt tcttacgtgt tacgcaaata aatgagaatc
     7801 attctcacat agaatactct cggtaattga gaatgtcaat tatacttgtg atattatgag
     7861 cgaatcttta gtattgatag ataaaaatga gaaaaaaata tttcttcata gttttccaca
     7921 attttttctc tattaaattt gctattttcc cacacgatac ttgttttcag ctcttttttc
     7981 aaaaacacaa aacttagtat tccacagttt ccacaacaca atatgtagtg tttgttgttt
     8041 gactttttta ctaagagttt tatactatct attatagata ataagaatgt gttagaggag
     8101 gcactcacca tgaacgtaaa aatcttttct aaaaataatt gtatgcaatg taagatggtc
     8161 aaacggtttt taacagaaaa tcaaattgct tttgaagaag tcaatatcga tgaacagcct
     8221 gaagcagtag actggttgaa agcacaagga ttccaaagtg ttcctgtcat tacttctgat
     8281 gcagaaacag ttatcggatt ccgtcctgat cagttgcgta aacttgccag ctaacatgac
     8341 taaaagaatc aaaacgtgat acatggattt gaagggcttg agacagcacc agtttttgtc
     8401 gcaaacttcc aaatcctttt ttaaagctta aaaacaatgc aatgatttgc aatcaagcat
     8461 catcaaatac gaaatgaagg ttgggcgtac gtatgagtct taaaaattta caagatgtca
     8521 gttatttcaa gctgaataat gaaatcaatc ggccagtcaa tggtcaaatc cctttgaata
     8581 aggataaaga agctttagtt gccttttttg aggaaaatgt caaaccaaat acgatgactt
     8641 ttccatctat tatggaaaaa atcaattact tgatcgatca agaatatata gaagcagaat
     8701 tcattcaatt gtattcacca tcatttattg aaaagctata tcaatttttg gacgagcaac
     8761 atttttcttt caaatctttt atggctgctt acaaatttta ttctcaatat gcgttgaaaa
     8821 ccaacgacgg ttccgcttat ctggaaactt atgaagatcg agtagccttc aatgcgcttt
     8881 actttgcgaa cggggatgaa gaattagcac ttgctcttgc agacgaaatg atccatcaac
     8941 gatatcagcc agctacacct tctttcttga atgctggacg taaacgtcgg ggcgaattgg
     9001 tgtcttgttt cttgactcaa gtcactgacg atatgaactc tatcgggcgc tcaatcaact
     9061 ctgctttgca attgtcccgt attggtggcg gcgtagggat tactttatca aatcttcgtg
     9121 aagccggcgc tcctatcaaa ggatatgagg gtgctgcaag tggtgtcgtt ccagtcatga
     9181 aattattcga agatagtttc agctattcta atcaattagg tcagcgtcaa ggagctggcg
     9241 tggtttattt gaacgttttc catccagaca ttattgcttt cctttcagca aaaaaagaaa
     9301 atgcagatga aaagattcgc gtaaaaactc tttctcttgg cgtgatcgta cctgataaat
     9361 tttatgaatt gacacgtaaa aacgaagata tgtatttatt tagtccatat agtgtcgaaa
     9421 aagaatatgg tgtcccattc tcttatgtaa atattacaac tgagtatgat catctagttg
     9481 caaatccaaa cattcgcaaa caaaaaatca aagcgcgtga tcttgaaaat gaaatctcaa
     9541 aattacaaca agaatctggc tatccttacg taatcaatat tgatacagcg aaccgcgaga
     9601 atccaatcga tggcaagatc atcatgagta atttatgttc agagatttta caagttcaaa
     9661 cgccttctgt gattaacggc aaacaggaat atgaagtatt aggaacagat atctcatgta
     9721 acttaggctc gacaaatatc gtgaatttga tgcaaagccc taactttggt caatctgtgc
     9781 gtacgatgac tcgtgcattg acatttatta cagatgcatc tgatatcgat gtcgtaccac
     9841 cgatccaaaa cggaaataag ctgaatcata cgattggatt aggtgccatg ggcttacaca
     9901 cttatcttgc aaaagaacaa atggaatatg gctcagagga ttcattagac tttacaaata
     9961 tttacttcat gctgttgaat tattggacac ttgttgaaag caacaatatc gctcgtgaaa
    10021 gaaaacaagt tttccataat tttgaaaaat cagcttatgc tgacggcact tatttcgaaa
    10081 aatacgtaac tggagaattc cagccaaaat cagaaaaagt caaagcattg tttgaaggca
    10141 tttttatccc aactgctgaa gattggaatg ctttgaaaca agcagtaatg aaagatggac
    10201 tgtatcatca aaatcgcttg gcagtagcac caaatggctc aatttcatat atcaacgata
    10261 cgagtgcaag tattcatcct atcactcgca tgatcgaaga acgccaagag aagaaaatcg
    10321 gtaaaattta ttacccagcg ccttatctat ccaatgagac gattccgtat tacacttctg
    10381 cttatgatat ggacatgcgt aaagtaatcg atgtttatgc aacggcacaa caacacgtcg
    10441 atcaaggcat gagtttgact ttattcatgc gttctgaaat cccagaaggc atttatgaat
    10501 ggaagacaac aacgaagcaa acgacacgtg atttgaatat tttaagacat tacgctttcc
    10561 acaaaggaat caaatccatt tattacgtac gtacctttac tgatgatgca gaagaaatcg
    10621 gaagcaatca atgtgaaagc tgcgtgatct aatatcatag atagattcgc ttattcatat
    10681 tttaattaaa ggagcattct catgtcagaa acatattatg aagcaataaa ctggaatgaa
    10741 attgaagata tcattgataa atccacttgg gagaagctga cagagcaatt ttggctagat
    10801 acacgtatcc cactttcaaa tgacctagat gattggcgta cattgtctca attggaaaaa
    10861 gatacagtag gacatgtatt tggcggtttg acactgctag atactgtcca atctgaaagt
    10921 ggcatggatc agttgcgtaa agatgtccgc actccccatg aagaagccgt tttgaacaat
    10981 attcaattca tggaatccgt tcatgccaaa agttattctt ctatttttag tacactgaat
    11041 acgaaaaaag aaatcgaaga aatttttgac tggacaaata cgaatcctta tctgcaaaaa
    11101 aaagctgagc gtatcaatga aatctacaaa cacggtacac cgctagaaaa gaaaattgcc
    11161 agcgtctttt tagaaacatt cttgttctat tcaggttttt atactcctct ttattattta
    11221 ggaaacaaca aattggctaa cgtagcagag atcatcaaac taatcatccg agatgaatct
    11281 gtacatggaa cctacatcgg ttacaaattc caattaggat tcaacgagtt acctgaagca
    11341 gaacaagaaa cgttaaaaga ctggatgtac aatcttcttt atgagcttta cgaaaacgaa
    11401 gaacgttata cagaagaatt atacgatcca atcggctgga cagaagaagt caagacattc
    11461 ctacgctata atgccaacaa agcattgatg aacctaggga tggatccact ctttccagat
    11521 actgccaatg atgtcaaccc aatcgtaatg aacgggattt caacaggcac aagcaaccat
    11581 gacttcttct cacaagtcgg aaacggctat ttgttaggtc atgtagaagc gatgaaagac
    11641 gacgattatt tgattggatt ggaataagga tttattttaa ttcaaaaatt tttcgaaaaa
    11701 taaaaagagt ttagcgtaca gatattttaa atgtacactg aactcttttt tatgcttatt
    11761 cacttgtttc ttccagcact tttggactgt ctaacttttc cgaaacatgt tccattcttc
    11821 tcaataaata gattttccgg atatttaata ttatcgtctt aatcactgca tagacaggta
    11881 tgcaaatcag catgcctaat attcctgcga cacttcctgc tccaatcaat accaagatga
    11941 tcgtcaaagg atggatattc attgatttcc caaataacaa cggcttgatc aaatttccat
    12001 ctaattgttg gatcactaaa atcgacaacg ccatatacaa agcttgaaat ggagagataa
    12061 acaaaccgac aatgattgct ggtaccgctc caataaaagg gccgacatac gggataatat
    12121 tcgtgattcc gcaaatgacc gcaagcaaca agctataagg ctgatcgaat attctcattg
    12181 ccaaaaagct cattacacca ataatcaaag catctaagat cgtactgctg atataggcag
    12241 ataatgtttc gtttaattct tttaccgttt ggcgtaactc tttacgaatc gctttcggaa
    12301 agaagtgaga caacgcatca ataaatttgt gcccatcctt gaacataaat agcaaaataa
    12361 atggaacggt aaataacaaa ataaaaaatt gcatcataaa tgaaatgatt tttgagacac
    12421 ttgcagataa actgactaat atgatattga acaaattact aagagataaa tttgctgatg
    12481 ctaattgttc ttccaaattg aaatttttaa actcttcccg ctgcgccaat tcatttaacc
    12541 atttgcttgt ttcatctgca tacattggca agctctgggt caattgaatt gtctgttcca
    12601 ttaactgagg cactacattc atgacagtta aaacaactaa aatgattacg accaaaaacg
    12661 tcaataaaaa accgaacact ctcgggatcc gatgcttttc gagaaaaaca acgattggat
    12721 cgaacatata atagataaaa ccagcaacaa gcaatggtaa aaaaattgcc gaaagcattt
    12781 tcaatattgg actaaaaata ttcggcattt gtaaaataaa gtacacgccg atgatcgtga
    12841 gtactagctc cactgtccag aaaaataatt ttgattgttt aaaacgtgat tgcatacatc
    12901 tcctccaagg tcctttgata cttctattct atcatttaac aaagagttac gcgctgagat
    12961 tttcatttgc ttaaaaaaaa caaaaaaaat aaacatattt taatgagtag acgagtactt
    13021 aaacaaaaac acggtttgga gtagtgacaa aaattatact gcagtccctt tttccaaata
    13081 aacggtgttc aaaagcttgc atcttcgtaa taagcccagc caaacgaaaa atataaggaa
    13141 ctatttttat ttggctgggc ttattacttg atgtaggaca tctattttac aacctcagat
    13201 catttattgc gcaatactga ctaaatgcaa ctttgtgata tttttgtgta cggacaactc
    13261 ctcgatcaca tcggcataag tgagcccttt tggaagatca atcgtataga tatttttgta
    13321 cactcggtag tcatcaacga attttacgtc aaaattcaca tcttcgatta cgatattttt
    13381 ctcttcaaaa taatcggtaa gaaaatcttt ggtttctttt ctatggataa attggatttc
    13441 taacttttta gtcgtaggta catggatcac gcgtttcact actgtgagtg caatagcaat
    13501 cccgataaaa ctgatgatcg caatggaata gtaacccatg ccgatggcga tccctaatcc
    13561 agcaattgcc cataaagaag cggcagtcgt aagtcccgtc accgattgtt tcgtgacgat
    13621 gatcgttccc gcgcctaaga aaccgacacc actcaccact tgagcaatca gccttgcttc
    13681 atctgaacga atcgttccag caagctgtgg atactctaaa gcatctctta atgcaccact
    13741 agcgatctca acttggatca atgcaatgat acatgctccc atacaaacta aaatatgcgt
    13801 acgcatacct gctggacgat ttttatattg tcgttcaaaa ccgattgctc cgccaaatag
    13861 catagcgatc cctaaacgta aaataatctc tggaattgtc aataccatat cattcatcta
    13921 aacaccctcc agtccaatat atcatgtctg aaaggagcag acaaaaaaag tgcaattttt
    13981 acctcttacg aaaaaaggac tgtgacaaaa tttttgtcat agtccttttt atgaataaac
    14041 ggtgttcaat cagctgaccc tcggtattac tcaacaaacg gcaaaatatg gggagctatt
    14101 tttcctttgt cttctctaat actcaggtca aaacgctgat ttcacaacct ctttagccta
    14161 ctattgaaaa ttacaactta cttgctgctt cttcatcgat gatcacaaca acattgtcgt
    14221 gattttgcaa tacacttgct ggcaaatgat tcgttacagg tccttcaatc atccctttga
    14281 ttgcatcagc tttgctttcg ccaaatgcca tcaagacgat ttctttactt ttcataattg
    14341 aaccgattcc cattgaaaca gcttttgttg gtacatcttc tgctttatcg aagaatcgtt
    14401 tgtttgcatt gattgttgat tctgttaagt caactactga agtcgttccg tcaaatgaag
    14461 caccaggttc attgaaaccg atatgtccat tttgcccgat tcctaagatt tggatatcga
    14521 ttggatgtgc atcgatgatt tgatcatact ttttgcatgc tgcttccaga tcttctgctt
    14581 ttccatctgg tacaaacgtt tctttgaatg gttttttatc aaataattgg acatccatga
    14641 aatgacggta gctttgttca tctgaaccgc ctagtccaac gtactcatct aagtttacag
    14701 aagtcatttc actgaaatcc aaatcgcttg aagtcatttc tttatataaa gtaactggtg
    14761 tgcttcctgt tgccaatcct aatacttttg cacctttgtt cataccttct ttgatgattt
    14821 caaatgcttt ttttccgcct tcttcagcgt tttttacacg aatgatttcc atagtgattg
    14881 ctcctttata ttttggtata gcccaattat agcattcttt ttttcttttt acaataatta
    14941 gtatagacca aattgcattt ttttcatttt cttgacaata aataggaatc cgtgttaggt
    15001 ttcataagat ggttcaatca aacaatccat gttgcatgaa aaccaagcaa gtgattcact
    15061 gtggacgctt tatgtctgca gtttttttat gaaaaaggag ttattatgag tatactgaca
    15121 ttaaacaaca ttacccagca atttggcgac aaaatcctct atgaaggtgt cgatctgcaa
    15181 ttaaatgctg gcgaacatct tgggctgatt ggacaaaacg gagccggtaa aagtacattg
    15241 attaaaatca tcactggtga gatcttacca gatgacggac agatccattg gcaaaaaaat
    15301 attcacaaag gttacctcga tcaatatgtg gaagtcgatg aaacattaac aatcgaagaa
    15361 tttctaaaaa ctgcgtacgc aaaagaatac gaaaaggaag aaaaaattgc ttttctttac
    15421 caaacatata gcgagacctt cgatgattcc ttgctggaaa aagctgggaa actccaaacg
    15481 gaattagacc aaggagtgtt ttatcaaatc gacaccttag ttgctgagat gagcagcggg
    15541 ttggggatcg atgtcttagg tttagattca ctgttgaaaa atctaagtgg tggacaacgt
    15601 tcaaaggtga ttttagcaaa actactttta gaaaacccag atgttctgat cttagatgaa
    15661 ccaaccaatc acttagatga tcagcatatc caatggctga cgcagtttct tcaggatttt
    15721 gacggtgcgt atatcgtgat ttcccatgac caagaatttc ttgatcagat caccacccat
    15781 atcgcagaca tcgagtttgg aaagattact aagtatactg gccatctaaa acaagcattg
    15841 aaacaaaagg aacaaaatcg cgaaagctat ttgcgccaat atcatgctca acaaaaacaa
    15901 atcgaaaaga ccgaagctta tattcgaaaa tacaaagccg gttcccgatc aacgatggca
    15961 aaaagccgac aaaaacaatt agataaaatc gaacggctga cgcctccagc ttcagcaagt
    16021 aaagctgtct ttgattttcc attctcgcct attgtcacga cattagcagt ggaaacaact
    16081 gatttagtca tcggatatga tcgaccgcta cttgcaccca tcaatttgac catccgcttt
    16141 ggtgaaaata ttgccattcg aggcttcaac gggattggaa aatctacttt attaaaaaca
    16201 ctgatcggtg agattgaaaa aataagtggc gatttccact tcccagataa cacaaaaatc
    16261 aattactttt cacaagatct gtactgggaa aatccattag aaacaccact acaatattta
    16321 agcagtcaat ttccaaaagc gactatcaaa gaattacgtc gccaactagc taaagcaggg
    16381 ttagttaatc aattagcaag tgaacctctc actacattaa gtggtgggga acaaactaag
    16441 gtgaaacttg cacagttgac aatgaaccaa ggtaatttac tgattctcga tgaaccgacg
    16501 aaccatatcg atcaagaaac gaaagaaagc ttacaagacg ggatacagaa atttccagga
    16561 acagtaatca tcgtctctca tgaacaagaa ttttatcaag atcttgtgca acgagtcatt
    16621 gagattgaac caaaataaac gtttgattga atagttgaaa aaaaggagct gtgacaaaag
    16681 ttttgtcaca actccttctt ctgaataaat ggtggccaat tagctgacct tcggtattag
    16741 ctcaaaaaac ggcaaaatat gaggagctat ttttatttgg ctattcttat tacttgatgc
    16801 agaacagctt ttcacaacct cttttcgtct attttttatt ttcgagattt ctctttcctt
    16861 taaaaacaac tgtttgaaag aagaacgcac atccttgaaa aacaagcccg ctaaccgtta
    16921 cacctaacca gccatactgc tgccacattg tcgtccctag caatgaacca gccgcacctc
    16981 caataaagta cataaacata aataca
//
LOCUS       DAIGSZ010000064        15275 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.064, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000064 DAIGSZ010000000
VERSION     DAIGSZ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.064"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            130..1500
                     /locus_tag="NOB31_002220"
     CDS             130..1500
                     /locus_tag="NOB31_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCI0974409.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(1630..2931)
                     /locus_tag="NOB31_002221"
     CDS             complement(1630..2931)
                     /locus_tag="NOB31_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCI0974410.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(3161..5119)
                     /locus_tag="NOB31_002222"
     CDS             complement(3161..5119)
                     /locus_tag="NOB31_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HCI0974411.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(5296..5562)
                     /locus_tag="NOB31_002223"
     CDS             complement(5296..5562)
                     /locus_tag="NOB31_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCI0974412.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(6072..8198)
                     /gene="pnp"
                     /locus_tag="NOB31_002224"
     CDS             complement(6072..8198)
                     /gene="pnp"
                     /locus_tag="NOB31_002224"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HCI0974413.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(8386..8655)
                     /gene="rpsO"
                     /locus_tag="NOB31_002225"
     CDS             complement(8386..8655)
                     /gene="rpsO"
                     /locus_tag="NOB31_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HCI0974414.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            8906..9469
                     /locus_tag="NOB31_002226"
     CDS             8906..9469
                     /locus_tag="NOB31_002226"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCI0974415.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(9722..10243)
                     /locus_tag="NOB31_002227"
     CDS             complement(9722..10243)
                     /locus_tag="NOB31_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HCI0974416.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(10246..11088)
                     /locus_tag="NOB31_002228"
     CDS             complement(10246..11088)
                     /locus_tag="NOB31_002228"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HCI0974417.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(11081..11806)
                     /locus_tag="NOB31_002229"
     CDS             complement(11081..11806)
                     /locus_tag="NOB31_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HCI0974418.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            11982..12278
                     /locus_tag="NOB31_002230"
     CDS             11982..12278
                     /locus_tag="NOB31_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974419.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            12846..14438
                     /locus_tag="NOB31_002231"
     CDS             12846..14438
                     /locus_tag="NOB31_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI0974420.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            14451..15191
                     /locus_tag="NOB31_002232"
     CDS             14451..15191
                     /locus_tag="NOB31_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCI0974421.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         4358 a         3160 c         2936 g         4821 t
ORIGIN      
        1 gattctttga ctcaattctt ggcttctttt tatggagttt cataaattat cattgatttc
       61 taattggtat tctcaggata aacgctatat actactaact aaattttaaa gatataagga
      121 gtttaaaaga tgcgcgattt aacaaaagga agccccgcta aactgatttt gatgttcact
      181 gttcctttac tgatcggaaa tgtttttcag cagttctaca atatgatcga tatgatcatc
      241 gtgggtcaga cgctaggtaa aaatgcgctg gcagcggttg gtgcaactgg aagcctgaca
      301 tttttgatca ttggctttgc ccaaggttta acagctggtt tagccattat taccgcacaa
      361 cgttacggtg caaaagatta tcggggtctg aagaaaagtt ttgctgctag tgttgtcatt
      421 agtcttgtcg tcactgtgat tttaactgtc ctaagtctcc tgtttattcg tccgatgctt
      481 caattgatgc aaactcctcc tgaaatactt gatcaagcac aaacatttat ttcaattatt
      541 ttattaggga tctttgcatc agtcagtttc aatttgcttt ctaatgtcat tcgcgcactt
      601 ggtgacagcc gcacaccact attctttctg atcattgcgg tcatcatcaa cgtcgtactt
      661 gatttgatct ttattatcta ttttggcatg ggtgtggaag gtgcagctat tgctacagta
      721 atcgcacaag tttcttccag cgtactgtgt ctagtgtata tcaagaaaaa aatgcctttg
      781 ttacagttac gcaaaaaaga tttcaaattt gaaaaagaag agtttgctgt acacctaaat
      841 gctgctttgc caatggcgtt tcaatcttcg atcatcgctg ttggtgctat cgtgttacaa
      901 gcagcactaa atagtctagg gacagatgtc gtagctgctc aagccgctgc tggtcgtatc
      961 gaccaatttg caaatcagcc gatgatgtca tttggtattg caatggcaac tttcactgca
     1021 caaaactatg gtgcgaaaga atatggccga atcttgcaag gggtacgtca aactttactg
     1081 atgagtgtcg gatttagtct cttagcaggt gctatcgtca ttttcttcgg tcatttcttt
     1141 gttcaattgt ttgttagccc atcagaaaca cgtgtatttg aattagcaca aacctacttc
     1201 aatatcaatg ggtctcttta ctggatctta gcagtcctgt tcattttacg ctacacactt
     1261 caagggcttg gacaaagcaa gatccctacg atcgccggta tgatggaatt gcttatgcgt
     1321 tcttttgcag ctatcgttct tacaggaatg tggggatacc caggagcagc agcagcttct
     1381 cctttagctt ggatcggttc tgttgccgtg ttgctttact cttatatgcg ttcgatgaaa
     1441 caattgaaac acatgggtga agaggaacat ttcacattag aacatgcaga agcaagatag
     1501 ccttgattaa aagaaatcgt tgcggctaaa aatgaaaact tttattgaaa atatcttctt
     1561 cgtttaccga aaacaggttt tttagataac aaaaaggctg tgacaaaaaa tgtcacagcc
     1621 ttttttcttt tattctattt ttctttccgt ggactctact ttgaaataat cgatatgtgc
     1681 atgctggtat tctaataccg tgaaacggaa tgatgcaatc tcaatgattg ttcctgcttt
     1741 tatttcttta tatcggctag aagcaaagcc cgcaagtgta gtaaaattcg tttcttcaaa
     1801 ctctggaatc tctacatgaa aataacgctg gaaatcatct aatgttagtt tgccggagat
     1861 gatataagag ccatctgact gttccgctat caatgcttcg tccaaatctg tctcatctcg
     1921 gatttccccg acgatttctt ctaaaatatc ttcaatcgtc actaagccgc ttgtccctcc
     1981 gtattcatct tttaagatag caatatgctt tccctttttt cgcatgatcg tcaataattt
     2041 ttttataggg atcgtttcag ttgttacgat cggctcttca atcaactgtt ctactgtcag
     2101 ctggtcatct ttataagatt gcttgatcaa atctggcaag gtgacataac ctaaaacatt
     2161 gtcttttgat tctaagataa ccggatagcg agtatgtcct tgttcaatcg aagcttttat
     2221 cgcttctttg acggtttctg aagcttcgaa tacttgcatg gacgtacggt ctacttgtat
     2281 atcttttgcc aaggtatcat caaattcaaa cacgttttcc aaataatgat attcttcttt
     2341 ggtcaactct cctttttcat aagaattcaa tgcgactaat gtcagctctt cttgagacaa
     2401 tgtctcttct ccttcagata cgagacgcac acctaatagc ttccctagcc ctgcagctga
     2461 atgattcaat acccaaataa aaggaaacat tactttataa aaataatgaa gtggtttaac
     2521 tacgaacaag acgaccttct ccgtattgac gatactatag ctcttaggaa gcagttcgcc
     2581 aataaccaca tcgatatacg taactaaaat aaatcccagc gccacagaga ttgtactgct
     2641 aatagccgaa ctaaaaggta gtttaccgat cactggttct agtaaagccg cgacagatcc
     2701 ttcaccgacc cacccgatga tcaaaccggt tagcgtaatt cctaattgac tagctgataa
     2761 atagttatct aaatggtgtg taacatgaag agctagcttg gcgttcttta cattttcctt
     2821 ttctagttgt tccaatcttg atcgtctgat tttcactaaa gcaaattcac ttgctacaaa
     2881 aaatgaagta attgcaatca tcaaaaataa aataatgaaa ttgataacca tattctcccg
     2941 cctttctctt tttctattgt accctttttc tacaaaaaga ttgaaaataa tgcgtattca
     3001 tatttaggaa taaaaaagga gatgcggcat ttttcagcca catctcctta tcacttcaaa
     3061 atcattgcgt tacttgttgc taaacagctt tttcatgacc tctgataaac ggtgttcaag
     3121 tagctgacat tcgacattag ttcaggtcaa agcgctactt tcacaaccgc tctttcaacc
     3181 atgttttccg agtatttcca atgataagcg gaacagtttc atgttttact tcgctgtact
     3241 ctagcccaaa ccatgtttct ggcgaggtag cgattttttt gattgccagt tttgcctgca
     3301 tgatttgacg ttgccatttt cctagagttg tcacattgga aactacttca tcaatcagga
     3361 caaattggaa atcgccaact tctcgccctg gtgtcagaga gtatctttgt ggctgttttg
     3421 gcaaacggcc ttgtttcatc aaatcatgga tgacttggcg aacatatacg ttgatttcct
     3481 gttggaccct gaaacctaag aacagattca cttggacaat aaaatcagtg tccatcatat
     3541 ctacttgata ttctttcgta tatggctcat ccgtcacttc cacatgaaca aaccaataga
     3601 ctcgtgctct tttaggccgt ttatctaaaa tcgaatagat gaactgtcgg ccaactttat
     3661 cttcagccat atcaggaacc aagaagacca catttgtctg atagattggt aaagaagtat
     3721 catcacgtaa ttctctaagc tgcgggatat aatctctcaa agacacatcc tcggttgacg
     3781 attcgcgaat aatgttccct tgttcccaaa taaacatcac gactaagatg atcaaaccaa
     3841 tcagaacggc tacaaaaccg cctcggaaga atttgacaac acttgagata aagaaaacga
     3901 cttctatcgc accgaagaaa aaggtaacta aatatgcaag ccaacgagaa tgcccatttt
     3961 ggataagata aaagtaaagc agtgctgttg tcatcaacat cgtcacagtg atcgatagac
     4021 cgtaagcagc ttccatatga tgagacgttc ggaatgtgac aaccactaga gaacaggcga
     4081 tccataaaat cagattgact gctgggatat acatttgccc gatactgttc ccaggataca
     4141 tgatctttaa ccgaggcagc agtttcaact tgattgcttc tgaaactagc gtaaacgaac
     4201 ctgtaatcaa tgcttgcgaa gcaatgactg cagcgactgt tgcaaaagca acgccgatca
     4261 cgatccaact ttgaggcatc atttggaaga atggattcag gttcttgatt tgctgtgctt
     4321 cagggttttg ataaacattc aacaaccacg cagcctgccc aaaataattg ataaccaaac
     4381 aaattttgac gtaaggccag ctcagacgaa tatttcgttt gccgacatgt ccaagatcgg
     4441 aataaagcgc ctctgcacct gtcgtagcca ggaaaatatt tccaagaatg aacaagccta
     4501 atttgttatc tgcactaaaa agcagctgga tagcataata aggattcagt gcacggataa
     4561 ctgtccagtc ttgactgaag ttcattaatc ccattacgcc taaaaaagta aaccaagcga
     4621 acatgattgg tccgaatgct tttccgacaa tatctgtacc aaagcgttgg accatgaata
     4681 aaacaaaaat aataactaaa gtgataatga cgatcacgtt ctggttatta ccgaaccggt
     4741 caaaaaactg cggaattcct cgcaagcctt caatcgcagt cgttaccgtc acagcagggg
     4801 tcaatacccc atctgctagt aaggcagctc ctccgatcat tgcaggaatg atcaaatatt
     4861 tcccaccttt tcggacaagt gtgtagagtg agaaaattcc accttcacca tggttatctg
     4921 cattcaatgc aatcacgaca tatttgattg ttgtcagtag agtcaatgtc caaaaaatca
     4981 atgagactga tccgataaca aaatcaggat tgattcctga caatccgcca ttatcttcaa
     5041 caatcgattt cataacgtaa agcggacttg tcccgatgtc tccgtagacg actcccatcg
     5101 ctacaagcag gccagccatt gatatctttt tggtattgtg cgttgttgcc acgtttttcc
     5161 ctcatttctt gttatatgga tatcctttag gtaagcttga atgatagatg atattcttat
     5221 ccatgacacc cgctttccta aattgcttct aattatccaa gtaacacact gaagtgtcaa
     5281 cttatttgaa taaaattatt ctttctttgg acgttctctg atacgtcttg ccacaaatga
     5341 ataaagagca aggcaaaaaa ttgcacccaa taatgctggt atcaaataaa aaccgccgag
     5401 ttccggtccc agtggtccta gtaaaaattc gccgagccaa ctacctaaaa aaccgataat
     5461 gatatttcca gatacgcctc ccgggacttc ctttcctaaa attgcgccag ctatcaaacc
     5521 taatataccg ccgataaata acgaccataa aaaattcagc atctcctttc cctcctttat
     5581 ccatatttct cacttttatt ttacgcttta ttcagaagga ctccaaaaat atgcgccaag
     5641 aaactccaga aaaaaagaag ttgtaacaaa agtgttcagc ttatttccgt agaagctgct
     5701 tctggaacac cgtgaatcag aggttgtgaa atcagcggtt tgacctgagt attagagaaa
     5761 caaacggaaa aatagttcct catattttgc cgttttttga gctaatatcg agggacagct
     5821 gattgaacat cgtttattgg agaggttgta aaaaagctgt tctgcatcaa gtaataagaa
     5881 cagccaagta aaaacagctc ctaatgtttt taacttggct ggacttatta ccgcagatgc
     5941 aagcttttga acaccgttta ttcgaaaaaa aaggactgtg acacggcttt tgtcacagtc
     6001 cccttttttc gaataattat tgtccccctg tcaccttcac gatcacaagt acattattcc
     6061 tatgaattaa attatttttc ttcatttttc gttgaaccat cttcgttcaa cattgctttt
     6121 cttgacagat ttacgcgtcc ttgtttatcg atttcagtta ctttcacaag gatctcatca
     6181 cctagtttaa caacatcttc gactttattg acacgatcgt ttgctaattg ggaaatatgg
     6241 acaagtccat cttttccttt gatcaagttg acgaatgcac cgaatttttc gatacggaca
     6301 actttcccta gataaacttc accaactttg acttctttgg tcaaatcttc gatgatcttg
     6361 atagcttttt tgatcatttc tgcatcagct gaagcaatac ttacttttcc atcttgatcg
     6421 atatcgattt tcacaccagt ttcatcgatg attccgttga tcgtatcgcc gcctttaccg
     6481 ataacatctt tgattttagc aggttcgatc tggatcattt cgatttttgg tgcatattgg
     6541 cttaattctt cacgtggagc agcaatcgtt gaagtcaatt cttctaagat ttccatacgt
     6601 gcttgttttg cttgagttaa tgcttcagtt aggatttgtt ctgtgattcc ttgaatcttg
     6661 atatccatct gtaaagcagt gataccatct tttgtaccgg caactttaaa gtccatatcg
     6721 ccaagatgat cttccagccc ttggatatca gttaggatcg tatagttttc accatcagaa
     6781 acaagtccca tcgcaatacc ggcgactggc gctttgattg gtacacctgc atccatcaat
     6841 gctaatgtgc cagcacagat acttgcttgg gaagaagaac catttgattc caatacttct
     6901 gctactaaac ggatcgtata aggaaattct tcttctgaag ggattacttg tgctaacgca
     6961 cgttcaccta atgcgccatg tccgatttcc cgacgccctg gagagcctgc acgtcctgta
     7021 gaaccaacag aaaattgagg gaaattgtag tggtggatga atcgtttgct gacttccacc
     7081 cctaaaccat caatgatttg gtgctctcct agaggtgcga gtgtacaagc tgataaagct
     7141 tgtgtttgtc ctcgtgtgaa caaacctgat ccatgtacac gtggcaataa gctgacctct
     7201 gatgacaatg gacggatttc atccaattta cgcccgtcag gacggatctt atcgatggtg
     7261 atcaattcac gtacgacatc tttttcaaga tcttctgtga tttgtttaac ttctttcaac
     7321 aagtgatctt catcttcatg acctgcaaat ttctcagcat aagcttcgcg gatatcgatc
     7381 ttcacctgct cgatattatc ttcgcgagca agtttttctt cagtcattac tgctgctttc
     7441 attgtagcgt aagaagcatc aaagatttct tttttcaata cttcatcaac ttgcagtaaa
     7501 gtcacttcca ttttttcttt ccctactgct tgaacgattt cttcttggaa agcaactaac
     7561 tctttgatag cgtcaaaacc aaacagcaat gcaccaagca tgtcttcttc tgaaacttct
     7621 ttcgcgccgc tttcaaccat attgatggct tgtttcgttc cggcaacagt caattcgata
     7681 tctgtttgtt ctgcttgttc tactgttgga ttcaagacgt actcgccatt tacacgacca
     7741 acttctacgc ctgcgattgg gccgtcaaat gggatatctg agattgatag tgctaaagaa
     7801 gaacctagca ttgctgccat agctggcgag cagtctgttt ctacactcat cacgatgttc
     7861 gttacttgga cttcattacg gaagccttct gcaaacatcg ggcgaattgg acggtcgatc
     7921 aaacgggcag tcaatgttgc ttccgtactt ggacggcctt ctcgtttgat gaaacctcca
     7981 gggattttcc ctgctgcata cattttttct tcataattga tcgttaatgg gaaaaagtct
     8041 gtatcttttg cttctttaga ggccacagct gcacttaaga ctactgtatc tccataacgg
     8101 actaaaacgg ctccgtttgc ttgttttgct agctgaccga cttcgatttg taagggacgg
     8161 ccgccccatg tcgttttgaa tacttgtttt tctgacataa cttctccttt tccttctcgt
     8221 gaaagcaaga cgctactaaa caaatgaaaa ctgccgaaag ccgtcttttg agcagctttc
     8281 atttggttag taggagtcca tctagcttga tcacggaatt ttacttaatt gatatacgag
     8341 taaaaaaagt gagattcatg tgaatcccac tctttttgac taaaattaac gacgcaagcc
     8401 taaacgtttg atcaattcgc ggtaacgttg aacgtcagtt ttacgtaagt aagctaacaa
     8461 gttacggcgg tgaccaactt ttttcattag gccgcggtat gaatgatggt cttttttgtg
     8521 cacgcgtgca tgttcattca agtggttgat ttcttcagtt aatacagcga tttgtacttc
     8581 tggagaacca gtatcccctt catggcgagc gtattcgttg atgatttcat tcttgcgttc
     8641 ttttgaaatt gccatttctt tcacctcttt cgattattcc cctgcgactg agtaaaacgt
     8701 tggtgattcg cttaaccaag tggcaggtca tgtgcctaga gcacacagct atactttacc
     8761 tgaaaccggg ttgaaaatca agtagttaat cattaagaaa aggtagtttt caaacaatct
     8821 tactactact tttccatttt tgtggtaaac tataatgcga aaatagactt gaaacacagt
     8881 cttttaagaa aggggtacat attccatgat tacaatggat gatatcattc gtgaaggaaa
     8941 tccgacctta cgcgaagttg caaaagaagt ttctcttcca ttaagcgaag aagatatctc
     9001 tttaggaaaa gagatgcttg agttcttaaa aaacagccaa gatccaatca aagctgaaga
     9061 actacactta cgaggcggtg ttggcttagc tgctcctcaa ttagatattt ctaaaagaat
     9121 cattgctgtt cacgtaccaa gtcctgaccc agaggcagat ggaccttctc taagtactgt
     9181 tatgtataat cctaaaattt tgagccattc tgttcaagat gcttgtttag gggaaggtga
     9241 aggctgttta tctgttgatc gagaagtacc aggatatgtt gttcgccatg ccaaaatcac
     9301 tgtgtcttat tatgatatga atggtgaaaa acacaagatt cgtttgaaga attatgaatc
     9361 gatcgtcgtt caacatgaaa tcgaccatat caacggtgtg atgttctatg accacatcaa
     9421 cgatcaaaat ccatttgcac taaaagaagg cgtattggtg atcgagtaga gaattggcag
     9481 gttccttcga tactatgcta caagaaagct ttataaaaaa ggggagtgct caaaagctgc
     9541 acttcccttt tttatgtttc tccactaatc gaaatttaga tagacatcta gaaatcgcaa
     9601 ttccaaaaaa ttctgtgtat tggatacgca tcttttctta ttttttctta tttcttccat
     9661 atgggtgttt atctcagaga tgatagaata gtttctagga taaaaagtag cagctacgat
     9721 gttatccttc gtagaggatt cctgcttcag ctagtttttg tttgatgttt ttcagcatat
     9781 gcttttctgg gtagcggatc gtatgcagat ggatgccgcc tgttaattcg gataacaaag
     9841 tagcattact tttttgataa cgtctcataa aggaatcgat atcttgtggc gttttgatgt
     9901 gcaaagttcc tgctaactca ccgtaaaggg gatgttccac aattacatca atgatttcac
     9961 caccattttc aacgattagt ctcagttctt cttctgtttg atcttttcca tgctggacag
    10021 cgattttact gatgtgccca gtattggttt cttctgtttc gaggatataa cctcttgctg
    10081 ttgccacgat acttttacct gcagctcgta gtaaagcaat atcgcctaca atgatctgac
    10141 ggctgactcc aaaagttttc gcaaacttgc tagcactcac tggtttttct gtatttgcca
    10201 aggtttgcat gatttgtttt cgccgtgtct ctccttcgat cacacttatt cctccttcat
    10261 tttgttttgg tattcgcgcg agtgtttcat caaatcaaca tacgtgtctg ttattgtttc
    10321 cttatatccc ttatttttca gcagactaac aactttatcc aatacttgct gctctctttt
    10381 tgcatcataa actgcttggt tttcttcttt tttcacttgt cctattttag ttaccgtatc
    10441 cattcttttt tctaataaag caaccaactc tcgatcgatc atatcgatct tatgacgtaa
    10501 tgtttcaaga gactcttctg ttagttcttc ctctactgtc ttgatgatac gagcaggatt
    10561 tcctgcaatc actacattgt cgggaaaaga tttggtcaca accgaacctg cgccgactac
    10621 tacgttgtcc cctagagtga cacccggcgt gacgataact cctccgccta accaaacatt
    10681 attaccgatt ttaatgggtt ttgcgtactc cagaccgctg ttacgtttca ctggatgtag
    10741 tggatgcgtc gccgtgtaaa gctggacatt cggagcgaac atgcagttat caccgatttc
    10801 aatcgtgctg acatctaaaa atgtacaatt gaaatttgca taaaaattct ccccaacaaa
    10861 tatattatat ccgtaatcaa aattgataac tggctccata tagatttttt tccctgtacg
    10921 gccaaaagtc tctttcaaca attgggatcg cagttccgct gattctgctt ggttgatgat
    10981 ttggctttga cttcttgcaa acatacggtc ggcaaccagc tcaggatcat tggcaaaata
    11041 aagctcgcct gcaatcattt tttctttttc ggttttgaat tcagtcataa tctgctccta
    11101 attcttgtat ttttttgaaa acaaccgctc cgtcttcttg aataaacgta taaggctccg
    11161 ctaaataaac aggcgtttga ttgattacta agattttggc tgacggctgg cgaaactgta
    11221 ccagatcaca aaacggatga acttgaaaac tcgttccaac aatgacgatc agctctgctt
    11281 ggctgacggc ataagccgcc tgctccatga ctccatcttg aaacccttca ccatataaca
    11341 cgatgtctgg gcgtatttgt cctccgcatg cttgatgttt gtcgctgtga agatattctt
    11401 tccagtctac cgtttgttga cattttcgac aatgacattg atacagactc ccatgaaaat
    11461 tgacgagttg cgggctttta gcctttgcgt gcaaaccgtc gatgttttgg gaaacaaccc
    11521 aaacattttt ttctttcgct agatgtgcta tttccaaatg aatgatattg ggttttgctt
    11581 caggatgata aatctttttg acaaattgat agaatttatc cggttcattc accattgctt
    11641 gatgactcag caagtattcc ggctgctcca tcccgtggta gattcctgac aaagatcgat
    11701 agtctggcac tccagaaggt gtggataccc ctgcaccggt caaaaatgta atttgctgat
    11761 aagctaatat ctcttttgct gcttcgtcta ctgttaattg tttcatgttt tgtcacctca
    11821 ctttccatta tagcccatac tcgaacaaat ttattgttga aaagtcagaa aaatgggaat
    11881 aaaaaagtgt tatgggcatt tgagcaattt atcacaatgt tcactgacaa aagaatgaaa
    11941 acgtgttaca atactgctgt ataaaagtga ggtgaatcga tatgttacca ttctttattt
    12001 attggggcgt tattctggct tgtatcgcct ggttagcgtt aagcgtttat ttctctgttt
    12061 tttatcttgt acgcaaagaa aatggaaatc tttgggcttt tgctttattc aacgtgattg
    12121 ccgcaattgt tttagccatt acattagccg tatatcgaac atggggctgg ggaatcaccc
    12181 aatactcaag tttgatttat ctaatattag ccatttatgg cgtcgttgtt cttttgcaag
    12241 cgatcctagg acgtgagcca aagaaagcgg cagcttaaat gatcgagatg gaactggaca
    12301 caggaaattt tctgttctag ttcttttttt attgtattac atacattttt gtgtataatt
    12361 atactatcgt ttgcaatgga tagatgattc acattttgat tgttttttcg gtaaaagtaa
    12421 agatttctat atttatcagt attttttcaa aaaccagcag ttatagattg acaaagcctc
    12481 tcgagtatcg taaacttttt ttgtataaat aactgaatac gagatgcctc aatcaatgag
    12541 gtagaggtcg cgagaatcat taaccctgtg gagtgaagca aacatggaga agcaggaata
    12601 gggaggatcg ccgaaatgtg cacttttttg cttggagtgt atgttgggac gcaagttaag
    12661 agcttgcgga ctgtcttagc agtgatgcta agttgcgcta tgttttgtga gaggtttatc
    12721 accttatgga attttagcgg cctttttata tctataaatc ggtcgctttt tattttttca
    12781 gataaagctt taccgcattt catctagacc gctcgtgtat catataatca gaaagggaga
    12841 aaaaaatgaa aaaaaatatg gtttcagttg ccgtactatt tgcttttgtc ttctcactat
    12901 tcagtgtggg atctctggca aatgcagatg aaaaaacacc gagcgatgag tttcgcgtag
    12961 gtatggaggc tgggtatgca cccttcaact ggtctcaaca aacagatgag aataatgcct
    13021 tgccaattca aggccaaaat agttacgccg gcggttatga tgttcaaatc gctaaaaaag
    13081 tagcagatgg tttagggaaa aaattagtca tcgtccaaac gaaatgggat ggtctggctc
    13141 ctgcccttca atcaggcaag atcgacgcga tcatcgccgg aatgagccct actgctgaac
    13201 gacgaaaaga aattgatttt accgatcctt attacgaatc acaattagta gtagtagttc
    13261 aaaaagatag caaatatgca aaagcaaaaa gtttagcaga tctttctgga gcaaagatca
    13321 ctgctcagtt aaatacattc cactatactg tgatcgatca gataccagat gtgcagaaac
    13381 aacaagcaat ggataatttc tcagcaatga gaacagcttt agcttctgga atgatcgatg
    13441 gttatgtcag cgaacgtccg gaaggtgtaa cggcaactag tgtgaacaaa gacttggaaa
    13501 tgcttgaatt cagcggtgca gatggcttcc agacaaaccc ggaagatgtt cagatttctg
    13561 ttggtatgcg taaaggcgac ccggatatcc aaaaagtaaa ccagattctt tctggcatct
    13621 ctaacgatga acgaaccaaa attatggacc aagcagtcaa agatcagcct gctgcaactg
    13681 atagtgaaga aaaacctggc atcatttctg atttcactac gatttggaaa caatacggca
    13741 atatgttctt acgaggtgct ggacttacct tgttcatcgc attgatcggg acagttgtcg
    13801 gtactacact tggattactg attggtgtct tccgttcggt acctgaatca ggaaatgcac
    13861 tgactcgctt cttccaaaaa atcggaaatg cacttctttc tatctatgtc gaagtattcc
    13921 gcggaacacc gatgatggta caagcaatgg tcatcttcta cggtctggca ctcgcttttg
    13981 gcatttcatt gaaccgaacg attgccgctt tgtttattgt ctctctcaat actggagctt
    14041 acatgacaga gatcgttcgt ggggggattt ttgcagtaga tgaagggcag ttcgaagctg
    14101 cgcaagccat tggtatgacc catggccaaa cgatgagaaa agttgttatt ccacaagttt
    14161 tacggaatat cttgccagca acaggaaatg agtttgttat caatatcaaa gatacagcag
    14221 ttttaagtgt aatcggcgta gctgatttgt tcttccaagg aaactctgct tccggtgcga
    14281 atttccaatt cttccaaaca tttacgatcg tcgggatcat ctacttagtc atgaccttta
    14341 cgatcaccag aatcctgcgg gcggtagaaa agaaaatcga tggtccttca gcttatacca
    14401 agcttgaaga aatcgacaat tcaaatttgc aggaataagg aggaagaatc atgaatgaaa
    14461 aaattattga aatcaaacat ctaagaaaaa gcttcggtga aaatgaagta ttgaaagata
    14521 tcagcgtaac agtcaataaa ggtgaagttg tgacgatcat cggttcttcc ggttctggta
    14581 aatctacttt cttgcgctgt atcaatttac tggaaaaacc aacaggcggc gagatcattt
    14641 ataatggaga aaatgtatta gctcctaaat ataatttacc taaatatcga acgaatctag
    14701 gtatggtttt ccaatccttc aacctgttca acaatatgaa tgtcttggaa aactgtatgt
    14761 ctggtcaaac aactgtcctg aaacgagata aagaaactgc caaaaaagta gcaatcgaaa
    14821 atctggaaaa agttggtatg gatcgttata tcgaagccaa accagcacaa ttatctggtg
    14881 gacagaaaca gcgtgtcgca attgctcggg cattatcaat gaatccagat gtattgctat
    14941 tcgacgaacc tacttcggcg ttagaccctg aaatggttgg cgaagtgctt aatacgatca
    15001 aagacttagc acatactggc ttgacaatgc ttatcgtgac gcatgagatg gaatttgcaa
    15061 aagatgtatc tgaccgtgtc atttttatgg ataaaggtgt gattgcagaa gaaggtacac
    15121 cagaagatat ctttgtccat ccgaaagaag aacgtacaaa agaattcctt tcacgtattt
    15181 taaatgctta ggatcaatag ctgattggga caaagagctg cggtgtttac cgcagttctt
    15241 ttttatgaat tactcataaa aggtaaattt ctgaa
//
LOCUS       DAIGSZ010000065        15229 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.065, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000065 DAIGSZ010000000
VERSION     DAIGSZ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.065"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            278..787
                     /locus_tag="NOB31_002233"
     CDS             278..787
                     /locus_tag="NOB31_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0974422.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="NOB31_002234"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="NOB31_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI0974423.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="NOB31_002235"
     CDS             2322..3302
                     /locus_tag="NOB31_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0974424.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="NOB31_002236"
     CDS             3424..4842
                     /locus_tag="NOB31_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HCI0974425.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="NOB31_002237"
     CDS             4913..6382
                     /locus_tag="NOB31_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCI0974426.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="NOB31_002238"
     CDS             6392..6859
                     /locus_tag="NOB31_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0974427.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="NOB31_002239"
     CDS             6895..7767
                     /locus_tag="NOB31_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0974428.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="NOB31_002240"
     CDS             7848..10382
                     /locus_tag="NOB31_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0974429.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10538..11311
                     /locus_tag="NOB31_002241"
     CDS             10538..11311
                     /locus_tag="NOB31_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0974430.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="NOB31_002242"
     CDS             11304..12095
                     /locus_tag="NOB31_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0974431.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="NOB31_002243"
     CDS             12105..12596
                     /locus_tag="NOB31_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0974432.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="NOB31_002244"
     CDS             12614..13024
                     /locus_tag="NOB31_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCI0974433.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="NOB31_002245"
     CDS             13028..14428
                     /locus_tag="NOB31_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HCI0974434.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="NOB31_002246"
     CDS             14451..14825
                     /locus_tag="NOB31_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCI0974435.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5286 a         2135 c         3045 g         4763 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactccta
//
LOCUS       DAIGSZ010000066        15137 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.066, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000066 DAIGSZ010000000
VERSION     DAIGSZ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.066"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            4..2376
                     /locus_tag="NOB31_002247"
     CDS             4..2376
                     /locus_tag="NOB31_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974436.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="NOB31_002248"
     CDS             2437..3897
                     /locus_tag="NOB31_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HCI0974437.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /gene="topB"
                     /locus_tag="NOB31_002249"
     CDS             3908..6112
                     /gene="topB"
                     /locus_tag="NOB31_002249"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCI0974438.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6128..6277
                     /locus_tag="NOB31_002250"
     CDS             6128..6277
                     /locus_tag="NOB31_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974439.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6352..6945
                     /locus_tag="NOB31_002251"
     CDS             6352..6945
                     /locus_tag="NOB31_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HCI0974440.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6958..7857
                     /locus_tag="NOB31_002252"
     CDS             6958..7857
                     /locus_tag="NOB31_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HCI0974441.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7860..8357
                     /gene="ssb"
                     /locus_tag="NOB31_002253"
     CDS             7860..8357
                     /gene="ssb"
                     /locus_tag="NOB31_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCI0974442.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8723..8983
                     /locus_tag="NOB31_002254"
     CDS             8723..8983
                     /locus_tag="NOB31_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974443.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9428..9634
                     /locus_tag="NOB31_002255"
     CDS             9428..9634
                     /locus_tag="NOB31_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HCI0974444.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9634..9885
                     /locus_tag="NOB31_002256"
     CDS             9634..9885
                     /locus_tag="NOB31_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974445.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            9901..10338
                     /locus_tag="NOB31_002257"
     CDS             9901..10338
                     /locus_tag="NOB31_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974446.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            10331..11038
                     /locus_tag="NOB31_002258"
     CDS             10331..11038
                     /locus_tag="NOB31_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974447.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11418..11597
                     /locus_tag="NOB31_002259"
     CDS             11418..11597
                     /locus_tag="NOB31_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974448.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11922..12185
                     /locus_tag="NOB31_002260"
     CDS             11922..12185
                     /locus_tag="NOB31_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HCI0974449.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12179..12529
                     /locus_tag="NOB31_002261"
     CDS             12179..12529
                     /locus_tag="NOB31_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCI0974450.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12553..13167)
                     /locus_tag="NOB31_002262"
     CDS             complement(12553..13167)
                     /locus_tag="NOB31_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0974451.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13480..13902
                     /locus_tag="NOB31_002263"
     CDS             13480..13902
                     /locus_tag="NOB31_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974452.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13912..14115
                     /locus_tag="NOB31_002264"
     CDS             13912..14115
                     /locus_tag="NOB31_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974453.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14326..14910
                     /locus_tag="NOB31_002265"
     CDS             14326..14910
                     /locus_tag="NOB31_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0974454.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5567 a         2454 c         3065 g         4051 t
ORIGIN      
        1 aacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ctagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccaaaaa
      121 atgacgaacg gtcaaccaat gaacgacaag aggaatggcc gttcatggtt taaccagcaa
      181 gaacgaatcg aaaataaagt ccaaagtctg agagaagaga tcaagcaaca agaagaatac
      241 gtggaaaagc ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcgg ctttttcagc cgccacgatc cgaaaatacc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctaga
      661 ccaactgatt ctatgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt cgaattgatc
      781 gatcaactca aaacattgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaggaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaaccaat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaagggt tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctatacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tttagaaacg ccagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagatta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaata tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagataaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagtcgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aaatcattta tgaagaagtc gcaaaagaag aaaaggtcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     3541 cacaaagtaa atgcgttttt tggccagcag ctttctgtta acgattcaat agaagccatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagtttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc gcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggactg gaacgatcaa ttgaagcatg agatccagca acaagaaatc
     3841 agaaagcaaa aacgtgccat gttgtttcaa caaggcagac aacaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     3961 tagcttctct aaagccactc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     4021 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gaattagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agaacatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagtag gcgccgatca aggaaaaacc tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagacg caaaagagac
     4381 ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     4441 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gcttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttgcaggaaa agattagaaa
     4561 tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg attcgccaag ttgaaaccga
     4741 gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagacac tttggaagcc atgcaaggct tgtatgaagg
     4861 gaaatatcta agctatccgc gaacggatac cccttacatt acggaagggg aatatgcgta
     4921 tctgttggat cacttagacg aatacaagca ttttttgagg gctgaagaaa tttcgactcc
     4981 tattcataca ccgaatagta ggtacgtgaa caacaagaaa gtccaggaac attacgcaat
     5041 cattcctaca aaaacagtta tgacagaagc gacgtatgaa agtctgacac ctttacaaca
     5101 agcgatttac gagcaagttt taaaaacgac agtggcgatg tttgcggaaa aatataccta
     5161 tgaagaaaca acgatcttga cgcaagtcca gcagcttcag ttaaaggcaa tcggaaaagt
     5221 accgatagat ctaggttgga agaagttatt tggcaaagag agcgacggaa aagagaagga
     5281 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtag atctacaagt
     5341 ccttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcgat
     5401 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     5461 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     5521 tatcaaggta gagaaaaata agcttgtggt gacgaataaa ggggttttgc tttgccaagc
     5581 tgtggaaaaa gagccgctgc ttacgagtgc cgaaatgacc gccaaatggg aaagctactt
     5641 gttaaagatt ggagaacgaa aaggaacaca aaccactttt ctagccaata tccaaaagtt
     5701 tgtctctcac ttattggaag tcgtcccagg acaaatccaa tccattgatt ttggatcgac
     5761 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     5821 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     5881 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggagatt attcaaaata gccgaacaag ccaaccagtg aaagggttaa aaggtcagaa
     6001 gggttcgttt gaagcaacga ttgttttaaa agaagacttc actacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact tcaagaaaag aacacgacgc acgacaaaat aatggagggt
     6121 taatcttatg cgtaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagccaaaat
     6181 tcgttcagaa caagagaaat tacgtgccag taaaagaaga cttcagcaat taaagaacca
     6241 gcaacggatt caaaaagaaa tcgaattaga tcgatagaca ttaaccttgt tacaaataca
     6301 ctatcatgat atatttaatg tagtgtattt gtaacaaaag gggggaagta aatgcaagag
     6361 aaactgaaag aattgttggc tattcgcgat ggaaatttat ctatgaagga agccagaaaa
     6421 ttaggaatcg cagcaaccac tgtacaaaga ttggtgaatc aaggaaaatt gatcaaagtt
     6481 gatcgtggtt attatgtaga ggatggtcat ggaatagatg atttattttg gcttcagcaa
     6541 cgtttttcca ggggaatctt ctctcatgaa acgactttag atatttacca gctttctacg
     6601 aatatgccga aattcattca cttaactttt ccccatggat ataacgttga tcgttcaatt
     6661 acaaaagagc agcagttaca atttcatttc gtgaagaaag aagtttatga actaggaaaa
     6721 gtagagggaa cttcctttca aggaaatcct attactatgt atgataaaga gcgtacactt
     6781 tgtgatattt ggaatccgag atatgaaatt gaatatgaaa tgaaattaga agcattaaaa
     6841 gagtacatgg aagacccatt gagagatcca agtaaattaa gagattacat gacaaaacta
     6901 catgtagaaa aagaaatgaa ataccacatg caaagcttat attgatggag gaaaaagatg
     6961 acaccgacac aatttgcagc aaaaacaaga aatttagcaa agaggacagg attaaatgca
     7021 cagttagtac aacggcattt tatgatggat cgtttaattg aacaaatttc tgaatctaag
     7081 tataaaaatg atttcatttt gaaaggtggc tttttattag gatcaaaata tggaatcgat
     7141 agaaggacga caattgatat cgacacgaca tttagaaata gcaaattaac tgaagaaaaa
     7201 ttgaagagta tttttaatga tttaactagg aaacccacga aagaaggtat tgttttctct
     7261 attcaaggaa tgaaggaaac aagagaagcc gatttttatc ctggatttca aattaaattg
     7321 gtggctaatt tagagaaagt acgtgtgcca tttaaaatgg acgtgacaac aggagattct
     7381 atttatcctg aagtagatac acactatcac caattaatgt ttgaagataa aaaggtggag
     7441 attccagctt atccaacagc acaaattatt gcagaaaagc taagtgctac gttcagcttt
     7501 ggcacagata attcgagagc aaaagattac tacgacttat ttaccattcc gaaactagaa
     7561 aatatcgata cgaaagagtt atacaaaagt gttcgaaata catttacaaa acgtggggat
     7621 acaaaaccgt tgtcctttta ttatgaaaga gaaatggata agatcatagg aaatgactat
     7681 ttggaaaagc agtgggaaaa atatcgctca gttaacacgt ttgcgaattc catttcattt
     7741 acagatacag tcaacgaaat tgatcaccta atgaaaagtg tgatcaaaat tgaaaatcaa
     7801 gaaagaaaac ggcagtttaa aagatcacaa caaatgaatc aagaaatgga gagataaaga
     7861 tgatcaataa tgtaacttta gtaggacgct taaccaaaga tccagattta cgttataccg
     7921 cgagtggtac tgcagtagcg acttttaccc tagctgtcaa ccgaaatttc acgaatcaaa
     7981 acggcaatcg agaagctgat tttattaact gtgtgatttg gcgcaaacca gcagaaacaa
     8041 tggtgacatt agctaaaaaa ggtagcttga ttggtgtagt tgggcggatt caaacgcgga
     8101 cttatgacaa ccagcaagga caacgtgtgt atgtgacaga agttgtggcc gataatttcc
     8161 aactattaga aagcaaagca gcgacagaaa gccgtgcgca cgctgatcaa tcgtccacca
     8221 gtccaagcac caccactttt gaacaacggg atacagcgac gcctaataac aatggattga
     8281 acgctttaca gaatccattt gggaatccat ttggtggaca atcaatcgat attagcgatg
     8341 atgatctacc gttctaagta gcattttcta ttggttgcat ttgctacggt ttatgttata
     8401 atttagtcaa caaaaagaat tttcaatcta taaccaaaaa ccactagctg gcgggctagt
     8461 ggttttcttt tacgtttcta ttataagaat taacgggtag gcttactgtc tttcttggca
     8521 aatttacaat caagccattt gcagatatag tgcgcggcta cttctgccat gattgcaaaa
     8581 acaaaatcaa aaagaatttt caaacctata acctcctccc cttgccagat taggccgggg
     8641 tagcagacag caagactatt atagcataat tgaaatatcc aaatgattgg atttttgcta
     8701 taattttagc gaggtgattg tgatgaacaa atatgttggt ttgcttgata aaatccgagt
     8761 aataaaaacg caaccgttat tggttcgctt tactttacaa acgattcatg aatcgattaa
     8821 ttgtgtagtt gcagatattg aaattatcga taaattgcta attatggatg atggaaaata
     8881 caatattgcc gtcacaggtc acttcaataa acgaaatcag ctagttattg ctagcatgta
     8941 tgttagaaat cccgatcatt ttacgcgatc gatgggcata taaaaaaaga agagttgcaa
     9001 tcctaatgta ggactgcagc tctttttgtt ttacatagaa acaagaaaaa tgaaaaggcc
     9061 tttttaggaa ggcgcgagcg ccttctcaat tgaaaaacct ctctcactcc aaccgccacc
     9121 gccgttcgag aagaaaggaa gtgaacgcta cgcgttcact aagataaagg gtcttgcata
     9181 gcaagacaaa atagaaaaaa cttcctctca ccaaaaggtt cgctcctgtt cgttatctct
     9241 ttattgattt gtcagaccgt caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     9301 gggtaaatgg cacgctgcac gcccttgtcc ttgtcgcttt tagttgattc attctggcca
     9361 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     9421 atcaatcatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     9481 ctatcatgca ccatatactg tcgaatgcga ttgtggagaa agagcgaaat gtatcaaaag
     9541 ctattgtttg tatcaatgtc caacatgcgg gaaaaaatat accttgtctt atggcgatta
     9601 tattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cacaacacaa attattgact
     9661 gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa agtagcagaa
     9721 gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga tgcaccgact
     9781 atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca agaaaacatg
     9841 gaaacttatg aaaacgaata ttggttaacc aaattagaga actaaaaagg agaaaaaaat
     9901 atggctcaaa attactatga cgaatttgtc aaattacctt tggataaaat ggcacaaaaa
     9961 atggaggata tgacattcct atacaatgag acacgtgtac caaaaaaaca ttataaggaa
    10021 agattgtcgg tagctgtgga agaaatgatt gaatcgggtg tcgaaatgaa tctcattgcg
    10081 acctactatc gaacgcttga agaactgaaa aagcaaaatg gacaatggtt tttccaagcc
    10141 ttactatgct tggaagcagg cgtcaagcca aacactatca aaccttctga ataccaagct
    10201 ttagaactaa cgtatgggaa atttgtcgaa acgaaaaaag ccaagactgt ttcaagtgaa
    10261 tggttggact acttagaaaa tgtcaacaag tatggcgcat gttacatcat gaaaaaggag
    10321 gacaacgaaa atgaataagg tgatttatca actaacaacg gaagatgtgt cacacttttt
    10381 aacaaacaaa gaacatttga atgaagtaat cagacggatt caaaaagact ttagttgtat
    10441 ggaagaaatg aagtacttta ttcaaagagt cgaagaacaa ttgtatttgg aaagtgaaac
    10501 gagtcaaacg aaggtcacag tcagcaataa ttatttagac gtgtataaac atcgtcctga
    10561 aacggtaaaa aaaggaacgg agcttctacg actagaaaca gaaaaataca tcatgaatgt
    10621 ttacctagaa aggagtgaac tggtcgaaaa ctttgtcagc tgcacgattt gcaggaaaca
    10681 ctattactca gaatcagaat attattcaat ttttgagagc atggaattaa tggaagaaga
    10741 aatggaagag ctaaacagca aaaatgcgac gatagacgat tattatcttg tatttactag
    10801 atttttgacg tgtggaacgg aatctatcgt gttaatggga atggattatg aactcgctgt
    10861 acccgaagca tttttgaggg aatatgtaga agaagtagat aacccaggcg acgactggta
    10921 cacgacttta actgattttt tagataccta cacttacgac gatacagaag aaatccaaaa
    10981 tgaacttgac cgtaaacgaa tgccatatca acgatttgaa aggaaaaaaa ggcaataatc
    11041 atttataccg aaaagtgaga atgtgtgaaa taagaacaaa aaccttgaaa ttaagggaat
    11101 ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataag
    11161 cgggcaaagc ccgataacct aagagaaaga aggagatcca tatgaataaa atcattcctc
    11221 tgttgttcgt actgtgtatt ggcgagatac ttatgcgtca tggtgcagct gtacatttaa
    11281 acttcgtagt attcttagga atactagtat tttgtttgat tttttggcgc tttgtgttag
    11341 cccttgtgag tctactattc aagttgattg cagccatatt tttcataggg ttatttcgat
    11401 gaaaggagag agtactaatg ccaattgcaa taggaaataa acggttaccc gtgacattag
    11461 atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtacggaaaa agtgaatcta
    11521 agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga tttgatatac
    11581 cagcactaaa aaagtgacgt cacttttcat ttgaagaaac aaaagtgata gcacttaatt
    11641 gttcctacta tttagaatat tttctatgtc ctttttattc cattttgtat caataactat
    11701 gaaatcttta aagtatccag atcaattttt ttcttacctg attctaaaga ttttgttttc
    11761 ttaaacatat tatgatttcc tttcgactat tttcatataa atgttaacat agtttatgga
    11821 ttcatggaat gttaatctaa tttaatagaa aaggataatt aagtatatac gttttttctt
    11881 atgtatgtta tactatgtat atacagaaag aggtgtctac tatggaaatg ttacctataa
    11941 aaaaatgggg aaatagtaat ggccttagat tgccaaagta tattatggaa tatcttggaa
    12001 ttcatacaga agacaaagtg aagataatac aagaagaagt aaacggtcag aagcggctaa
    12061 ttatcgaagc ggctaatata gaaaatgaat taacaattga acagttattt gaaaattaca
    12121 ctgatgaaag aaatcatgtg acgattcaaa atttaggtga agcagtaggt aatgaaaaat
    12181 ggtgagaaaa cctagacaag gcgatattct attattgaat acagcacctc gatctggaca
    12241 cgaacagaca ggtaaaagac cttatattgt tttaagtcat gatattattg cggattatag
    12301 taacgttgtt acagttgctc caatttctag tacaactaga aactatccgc tatatgtaaa
    12361 tataaactca gaatatgaaa tgaagacaac aggaaaagta ttattagatc aactaacgac
    12421 aattgattat gaagccagag agtgtatttt tttggaaaaa gcgcatgata gtttagttga
    12481 ggagttattg atgaaagtta gaacagtttt tcaaaaagta agcaaataaa atagaaacag
    12541 cagcatgatc aactattcgt gattgaccat gctgtctttt tttattctat atacggtttg
    12601 tctcgtaaca ttgtagtctt ttgcaatctt agcgatcgca acaccttttt ttagatcctc
    12661 aacgatgttt ttataaacaa gacgacgttg gggatctttt gcattggcac tgtatagctt
    12721 aggacgtcct ttataaacac cgttcgcttt tgcaatctta atgccttgtg cctgacgtcg
    12781 tttagattcg gtacgttctt gttcagcgat catggccaaa atttgaatga tcaaatcttt
    12841 aatgaattta tccaggagag gattgccaat tgcttcggcc atgatcggta gacttgtgat
    12901 gatcagctgc acatttttct tcttcaagta attgactgaa gcgatgatct cgtcgtaatt
    12961 tcttccaagt cgatcaatag cttccacaat aaaaatatct tgatctcgga cgaaatccag
    13021 tgcttcttga aaaacaggtc gatgagtaat cgttgcgcca gattgtttct caatgaaaat
    13081 tctctctgca ccgaattttt tcatttcttc aatctgccgt tgttcatttt gatcgatgga
    13141 tgagacacgt atgtatgcaa ctctcaaaat ttttacctac tttctgcaac tatttaaaaa
    13201 acaccctaat catacacgag aaaaccagat ttttcaatgt cgcggtcgtg tctagttagg
    13261 gtatacctta tatagacaaa aactaatgat ggaggaaata gtatgtgtca cttttctttt
    13321 taaatggcaa tattttttgt aaataaatgt caatcaagaa aatttaaacg attatgacat
    13381 taaaaatata ttttatgaat tttctagtat ataacttgat ttatctgtta agatttatta
    13441 agaaacgttt tcttattttt gatttcgagg tgatagacaa tgaaaaataa gtttatttta
    13501 tctttaggta ttttaactat tggaattagt gtaactggaa ctacaattcc tacatttgct
    13561 gatagtacaa atgaaccaac tactgtagta gataataacc aagaattaac tcctttagat
    13621 aggaacggaa tagccattgg taacccaact aacgacttaa ctgttactga aaattattta
    13681 atagtttctc cattacttgc tcgagcagct tctaaaacga tacgagtgac aggaacgatg
    13741 atttttgata aagttggttg gccttctaga cctcctcaat cacggaattg gaaagaaaaa
    13801 agaaatggtt attggtacta tggaaaattg tatttacaaa gttataaatc agctggaaac
    13861 aattggattg cgacttattc aggaacctta actagaaagt agggattttt tatgccagaa
    13921 tttgtgaaca caccaaattt ttatcaagat agcgatattc taagtaaaat taatttaccg
    13981 aaagaagaat cagctttaca agttcagcga actttacagg agacacaaaa aattcaaaaa
    14041 tcaatttcta atctagaaga ttctgaagaa aaaagaaaaa aaagagacca aaaaacatat
    14101 caaaaagaaa aataatgatt ttaaaaaaag agtgtctagt cgacattctt tttttctaat
    14161 tgaaagtgtt cataaaatca cccatttctg gacactttct ttttttgctt tatttttcaa
    14221 aaaaacaatt catttcatgt tcataaaccc ataacaatat ctatgttcag ttaaactata
    14281 tggataaagt tatgttacaa taaaattaat gaaggagtga tttttttgaa aataggatac
    14341 gcccgggtat ctactggttt acaaaatttg gatttacaag aagacagcct aaataaattt
    14401 ggttgtgaaa aaatttttac tgatcatatg agtggggcaa aaagtaatcg accaggatta
    14461 gaaatggcca ttgattttgt tcgctctggc gatacacttg tcgtttggcg cttagatcgt
    14521 ttaggtagaa atatggaaga tttgatttca atcgtcaatc gactgaatga gcgtggtgtg
    14581 agttttcata gtattcaaga aaatattacg atggacaaat caagttctac aggacagctc
    14641 atgtttcatt tgtttgcggc atttgcagaa tttgagcgta atttgatcct ggaacgatcc
    14701 gcagcaggac gagcagctgc tcgtgcaaga ggacggtttg gtggtcgtcc tgaaaaattg
    14761 tctgaacaag atttggaatt actgaagact ttagtggata gcggtacacc tattaagact
    14821 attgcggaac ggtggaacgt ctcaagaacc accatttatc gttatttggc aaaaatggag
    14881 gagaaaaatg gaaagacaaa ttctcattag tttttgtcat ttaatgctga aaatttttgc
    14941 catttatcta gaaaagtgac aatagtatga gaattttttg taagtgtcta ctgataactt
    15001 attctcaaat gttgtaagga ttttattcat ttgttaatat taaagaacgg aactccaaaa
    15061 aagtccgtac tctaatttgc agtctctcac tcttttagag tgagagtttt tattagattt
    15121 tcaaattaat tagtaaa
//
LOCUS       DAIGSZ010000067        14994 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.067, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000067 DAIGSZ010000000
VERSION     DAIGSZ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.067"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..608
                     /locus_tag="NOB31_002266"
     CDS             <1..608
                     /locus_tag="NOB31_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974455.1"
                     /translation="ENQLFAGDVLEIVLNDQAGEAAAKGVQNKPSTNDEIGNHNPSDT
                     PVVYHDAPPFAPATKIVVEGGLSFLAPSKLDCGQIKATGLTQEAFGQMDIQEKLWIYD
                     QRETKSPWILTIKLSQPFTTDAGFSMQDVLYFKKAEEYQLVNEEELEIVRGQNSTNVQ
                     TDYSEYLNNGRAFKLVLTKENQIAGNYSAEMTWTLADAPTE"
     gene            628..1656
                     /locus_tag="NOB31_002267"
     CDS             628..1656
                     /locus_tag="NOB31_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCI0974456.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            1653..2411
                     /locus_tag="NOB31_002268"
     CDS             1653..2411
                     /locus_tag="NOB31_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCI0974457.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(2497..3237)
                     /locus_tag="NOB31_002269"
     CDS             complement(2497..3237)
                     /locus_tag="NOB31_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0974458.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3298..4551
                     /locus_tag="NOB31_002270"
     CDS             3298..4551
                     /locus_tag="NOB31_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCI0974459.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            4852..5100
                     /locus_tag="NOB31_002271"
                     /pseudo
     CDS             4852..5100
                     /locus_tag="NOB31_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5222..5548
                     /locus_tag="NOB31_002272"
     CDS             5222..5548
                     /locus_tag="NOB31_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCI0974460.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            5616..6329
                     /locus_tag="NOB31_002273"
     CDS             5616..6329
                     /locus_tag="NOB31_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HCI0974461.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            6639..7491
                     /locus_tag="NOB31_002274"
                     /pseudo
     CDS             6639..7491
                     /locus_tag="NOB31_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            7612..9477
                     /locus_tag="NOB31_002275"
     CDS             7612..9477
                     /locus_tag="NOB31_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0974462.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            9525..10934
                     /locus_tag="NOB31_002276"
     CDS             9525..10934
                     /locus_tag="NOB31_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HCI0974463.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            11042..11743
                     /locus_tag="NOB31_002277"
     CDS             11042..11743
                     /locus_tag="NOB31_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0974464.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            11902..12381
                     /locus_tag="NOB31_002278"
                     /pseudo
     CDS             11902..12381
                     /locus_tag="NOB31_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            13229..13804
                     /locus_tag="NOB31_002279"
     CDS             13229..13804
                     /locus_tag="NOB31_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HCI0974465.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            13804..14244
                     /locus_tag="NOB31_002280"
     CDS             13804..14244
                     /locus_tag="NOB31_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCI0974466.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            14260..14961
                     /locus_tag="NOB31_002281"
     CDS             14260..14961
                     /locus_tag="NOB31_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCI0974467.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         5066 a         2485 c         3161 g         4282 t
ORIGIN      
        1 cagaaaatca actttttgca ggagatgtat tagaaattgt attaaacgac caagcaggag
       61 aagctgctgc taagggtgtg cagaacaagc caagtaccaa cgatgaaatt gggaatcaca
      121 atccaagtga tacgccagtt gtttatcatg atgccccgcc ttttgcacct gctacgaaga
      181 ttgtagtaga aggtggtctc tcatttcttg ccccttccaa actcgattgt ggtcagatca
      241 aagcaactgg gttgacgcaa gaagcatttg gccaaatgga tatacaggaa aaattatgga
      301 tttatgatca gcgagaaaca aaaagtccat ggatcttaac gataaaatta tctcagcctt
      361 tcacaaccga tgcaggattt tctatgcagg atgtcctata tttcaagaaa gctgaggagt
      421 atcaattagt gaatgaagaa gaactggaaa ttgtcagagg acaaaattca acgaatgtgc
      481 aaacagatta ttcagaatat ttaaataatg gtcgggcgtt taaacttgtc ttaaccaaag
      541 aaaatcagat agctggtaat tactcagcag agatgacatg gacattagca gatgcgccga
      601 cagaataaag atcaaggaga atgattgatg aatcgaatat ggaataaaag tcatcgaaac
      661 aactgctctt tacttctgat ccttctcctt ggattcatcc tttggcagac acctgtccat
      721 gcctccgaat tcaattttgc ggtagatttt gaattaccgg ctaatcagat tgataagaac
      781 aaaacatata taaatgtaag gatggagcct gggaaaacac aggaaatccc ctacacggtc
      841 tttaaccgaa cagataaatc agtaacagtt gagacattga tccactccgc tacgacgaat
      901 tcaaacggtg tgatcgaata tggagaatca aaaagtaaat ttgatgaaac attaagttat
      961 gatatgaaaa acttagcaaa aacagtggga gaaataactg tccctcctca aagtgcggtc
     1021 actgagacac tttcactgaa agctccagaa aaagagctgg ctggtgtggt cgcaggagga
     1081 atcacgtttc aagaaaaaaa agagaacgtt tctaacaaaa gtacagttgg tgtcgtcaat
     1141 cagttttctc aagtgaaagc aatcttgatt cgaaatagcg aaaaagagtc ttccccaaat
     1201 ttgaaattaa aaaaaactta tgcggatcaa agcgatggaa gaaatgtgat taaggcgaat
     1261 cttcaaaatc caaatgcttc ttatatgttc ggcttgacta catcggttga aatctacaaa
     1321 aaagaaacaa aagagcctta tctttcaata aaaaaagaaa aaatagatgt agcacccaat
     1381 acaaattttg atttacttgt cccattagaa ggaaaaaaat tagctccggg acattatcaa
     1441 gcggttgtga agggtgcttg gaaagaaaaa cgctggaatc tccataccga ttttgaaata
     1501 actgatgatg cagcggacca attgaatgaa aaggatattg atttaaaaaa tcagccagaa
     1561 acatttgact ggcgatggct gatacttgtt ggagtcattc ttattggctt atttgctgga
     1621 ttatttattt taaaagaaag aaggaaaaag aaatgaaaaa aacaattgca ttaagtaccg
     1681 ttctagctgg aagtctatta ttatgtacac aaagtgtttt tgctgagaat aagagctcag
     1741 ccactacaga aggaacgatt tctgtaacaa aaccagatgc cgcaaatcct gaagacgttg
     1801 ttccagttcc tcctgttgat ccaaatgatc ccgatacgcc gtttacacct aacgaaccaa
     1861 atcagggaac atccggatta ctgacgattg accaagctcc agatcttgat tttggaacaa
     1921 tcaagttagg tacagcaaaa acagtatatg ctgcattaca aaacggaacg gacagtacag
     1981 ggacagcaac acaagtacag aatttcgtac aagtaacgga taaaagcgga atttatgccg
     2041 gttggaaact atcagtcaaa cgaacagaat ttattggtac aacatctgat acgaataaac
     2101 taactggttc aaaggtgaaa ttcaaaaacg ccgtgattcg aaatagcgca actaatagca
     2161 gtggaacgcc atctactatt tctggtactg gcgctgaagg aattgagatc ccagcagatc
     2221 aggcagtaga tctagtaact gcaggagcaa atgaagggat tggcacatgg atttattcat
     2281 taggagagaa tgtggaacaa gggagacaat cagtggaatt atttgttcct gtatccaatt
     2341 atgccgtaga caactacgtt tcaacattca catggtcgtt aacagatgct cctacagaag
     2401 ggaaagcgta aaatcaaatc aatgacttca gggagtggag ccgattcaag gccaactccc
     2461 tgaaatctgc tatgcttacg tctcagctct tattcatcaa ctcgaagcag ttttttggaa
     2521 gtcatggaaa cgttcctttg tcttttcaaa gatctttcga ccaacgagta aggagtcacc
     2581 attgaaaaat tctaacacat aatgagcaga atcaattttc tgcaattgcg ataagttgat
     2641 acagtaagat tttaatagta aaaagtaagc atacttttcc aactctgtct tcaattgttt
     2701 taaagaagta ttcactaatt tatcttctgt agttgttttg accataactt ggtttttcaa
     2761 acctttgata ctttcaatat ataaaatttc ccgaggatac aggacgagac ttccaccttt
     2821 ttgatcaata aagattttat cgacatttac gatttgctgt tctttccaat tgatctgttc
     2881 tagcacttga cgaatttgtt cagataaatt cctgtctttt ctgatatatc caatcggaag
     2941 gattttccga ttgatgatct ctactgcaaa attcgtataa gcggtgaaaa aaacaatatt
     3001 actatgtgca ttttttttac gtatttgttc ggcgacatca atacctgtga gtgattgctt
     3061 caagtcgata tcgataaaga aaacatcgtg attatcaata gtacccaact ggatcaactg
     3121 attgatttga gagatagaag tgagctgcac gatattctcg atatgatgat tgaccaattc
     3181 tttgatgatc cattcgctgt gaaactggtt atcttctatg ataaaatact ttttcatatg
     3241 caggctccta ttaaaaaaat atgtgtacat tttgaaacaa aacaatggag gaataagatg
     3301 gtcgcaacag tgacacttta tttgaccttt actttgattt tagatttagg tatctattta
     3361 ttcttttcga aacaactgct agtaaaaaac agctttggtt ttatagcttt gatggtggtg
     3421 acacttttat ttcctatccc taaagtgagc tttccttacc tagttggctt attattgatg
     3481 tttctttttt attttactac gaaaaacctg tttatcagct gtttgatcag taatcttttt
     3541 tttgctatca ctggactcag cttttttctg gtttttgatc tgatggatta tttaggaaag
     3601 agacatcttg gaacagcaag tttttttgca ctacttatcg catttatttt ctatctatta
     3661 gtaaaaagta tagacaaaca gacgagattt ctcaacttgc tttttactta tccaactgaa
     3721 cactattttg gaggtatttg tattttatta agctggggcg tgatttactt ggtattggga
     3781 agtgttcact tccgctcatc taattatctg cttctatctc ttttgtcgat agtcatcagt
     3841 tttttttctt tgtttttttc cattatgttg atcagtttcc aagtaaaaga aagacaacat
     3901 caggaatcgc ttcaactgta tcaaataaat gaagaatatt accatcatct agaggaattc
     3961 aaacatgatt ataaaagtct actgttttca ttaaaaatta ctcttcagga aaataaaaaa
     4021 gaaacgttgg aatttttaga aatcttagaa gatcattctg cagctatttt tgaaaaaccg
     4081 caaatacaac agctaacaaa tattgtatcc ccagctgtca ggggtgtctt tttaaaattt
     4141 ctagaaaaag cagaatcgga gaaaatcccg atccaagtag ttattcctgt cgaagtgaaa
     4201 acaatcccga ttgatctggt tgtttttatt cgctgtttat ctatttttat ttctaacgca
     4261 ttcgatcatc gtgtagccga tcagagtccg attacgatca atctgctgga agaaaaagag
     4321 ggattacgtt ttagtatagc gaacaaggca aatccgacga atttgacgct atcggagatg
     4381 gtcaaaagag gaaaaacctc taaaaaaaat ggcgggttag gtctatacag tgcgaaaaaa
     4441 atgttggatg tttacgaaaa tgcagaacta aaaatcgaat tttcaaaaca gaatcactat
     4501 ttttttgtag aaatgtatct ggcatctaga aagagcaaat cagcctactg acttactgtc
     4561 aaaggataag cttgaggaaa gtctacacgg agatagagac aacaacacag catattcaaa
     4621 agaaacagaa gcgtgatgac cgttgtcacc cttctgtttc ttttgctatg tagttaaaca
     4681 aagtagttga cacttccgct acttagtatt agtacgaaag tatacttcat gatactaagt
     4741 agataagaag tgaaaagcgg aacccacgat cgtcaaaatg ctaactgctt tgcttacacc
     4801 agataaaggg aagagcaata tcgcttattt taggcgtgga gaagcaagaa aatccctacg
     4861 atcacacaaa aaatgctgac ccagcagtta agagagttag aacaagatgg cattgtccat
     4921 cgaaaagtct ataaccaagt cccgcctaaa gtagagtact cgctcaccga agaaggaaaa
     4981 tcattaagag agattctagt agcgatgtct gtttggggag aagaacgtat cgaaaaacaa
     5041 aaagcctcag gggaagaagt cacattactg catacacatg gtggctacct aaattactga
     5101 tttctatgac atttatttta aataaaagaa aacaggagtt tttttaaaag catcatctat
     5161 tttttatgta aaaaaatggt atgattaatc aagtaagaaa tgattggaag aaggcaagca
     5221 aatgaatagc atggaaaaag ttaaccagtt tagagatgaa cgtaattggc gacaatttca
     5281 taacgaaaaa gatttggcta tttctatttc tttggaagca tctgaattgt tagaactttt
     5341 tcaatggaaa acgccggaag aagtaaaaga aacacaatta gaacgaatca aagaagaact
     5401 ggcggatgta ttgatctatt catacatgat ggcagacaac cttcagctgg atctagatga
     5461 gatcattgaa gaaaaattga tcaaaaataa tttgaaatat cctgtagaaa aaagcgcagg
     5521 tgtacgaaaa aaatacacag agttttagaa atgtgtcatt cggctgttgg aaagagcaaa
     5581 agaaaaacag taaaatgagt ctggagggag agaaaatgaa aaaaaaagga aaagcaaaaa
     5641 gatggctagt caatatcctc ttgttcctct tgttattagt aggactagct ttgattttca
     5701 atgaacagat caaggattat cttgtcagag agacaggaga taaatatgct atagcgaatg
     5761 taacaaaaga agatctgaaa aagaataacg ataaagatgt cagttttgac tttgatgcgg
     5821 tagaaccaat gacgacagaa ggggtcatga ggtcgcagat gagaggaaca gatctaccag
     5881 tgattgctag tatcgcagtc ccttcagttt caatcaattt accgattttc aaaggcttgg
     5941 ataatacgtc actactttac ggagcaggaa cattatctcc agatcaagaa atgggaaaag
     6001 gaaattatgc cttagcaagc catcgtgcaa cgaaccctga attgttgttt acaccgctgg
     6061 aaaatttaga gatgggtgcc aagatctatt tgacagattt agaaaatgtg tatacataca
     6121 aaacattttt taaagaaaaa gttgctccta cagataccca attactgaat gaagtcgagg
     6181 aaaaagaaat tgtcacacta attacttgtg gcgacatgga cgccgtcacg cgactagttg
     6241 tacaaggaga actggaaagt gttacaccga taaaagatgc gacagatgat atgagatctg
     6301 ctttcaatct agagacaaaa acattttagg atactgggac ataagtcgtt acagattaaa
     6361 aacagccaaa ggatatgaat cgataaggaa aaaccaattt gctgaaaaaa agaggaacgc
     6421 aaagaggtgc atctctgatt tggttgtttt ctagatagac ttgtgttcca gtttttttat
     6481 tttttatatg aaaaggcttg cataaataaa aattcgatgg tatgatgatt ttgaataaga
     6541 aatggattgt tactgtacgg caggcaaaac cagaattcag ctaagaaaca gtaggcgaat
     6601 tctaggtttt tttatttttc ttgagagggc gaagcaaaat gaaaattgat aaaattttga
     6661 ataacaatgt cgtcatttcg aaaaatggat tcggggaaga agtcgtttgt atgggaaaag
     6721 gactagcttt tcaaaaaaaa gattggggac gagatttcgc cagaagcggt ccaaaaagaa
     6781 tttattttaa gagattcttt tgctaaaaac caattccagc agctgatggc tgatattccg
     6841 gcagaggaga tcgaatgggt caaacaagta gtcgaactgg ctgaagataa actaaaagtt
     6901 gaattttcgc ctaatattta tctgacattg accgatcatc ttcattatgc gatcacacga
     6961 gcaaaagaaa atatccaact gcctaatcca ttattatttg aaacaaaaaa attttatccg
     7021 aaagaatatc aagcagcgaa agaggctctt ttgttcgtga aacaaaagac gggtgtggaa
     7081 ctttctgagg atgaagccgg ttttattgcc tttcattttg tgaatagcca acaaggaaac
     7141 gaagacatgc aagtgacgat gaccgctacc acaatggtaa gagatatact gagtatcatc
     7201 agtaaattct tcggcatcgt gttcgatgaa gaatctttga attatcagcg tatcattact
     7261 catctgcagt tttttgccca gcgttatctc aaaggggaag gatctgacga gcaagatgaa
     7321 tttctctacg cattagttca aggaaagtat ccaaaagcgt ttcattgtgt cgaacggatc
     7381 aatgagtatc ttcgacaaac gcaaaaacag gaaatgggga tcgcagagca gatttattta
     7441 acgattcata ttcaaagagt agtaagtgag aaaaaaagca tccaatcata aggattgtta
     7501 ctgtatggca ggcaaaacct ggattgaaaa aataggttca cgaatgtttg tgactgtttt
     7561 tttcaatctg ggtttttatt ttttaaataa aaaagaaaga aggaaaaaac aatggataat
     7621 caagcagttg gtcgtcgtgt atgggaagcg gtaggaggac aaaagaatgt caaaagttta
     7681 gtacattgtg ctacgcggtt gcgattcaga ttaaaagatg aatctttagc agatacgcaa
     7741 aagttaaaag aagacccgga cgtgatccaa gtcgtacaaa gtggcggtca gtatcaagta
     7801 gtgattggca gtaatgtagc agatgtttat caatcgatcg tggatgagga aggtcttgca
     7861 gtttcggagg atggaaaaga agagtccaaa aatattttga atcgtctgat cgatattatc
     7921 tctagtatat ttacaccttt tctaggggcg atggcagccg ccggggtatt gaaaggattc
     7981 ttatcattgg caacggtgat gggctggctg acagctgata gcggtactta tcaaatattg
     8041 tttgctgcag cagatggtgt ctttaccttc ttacctgtca tgcttgcttt tacagcagct
     8101 aaaaagttca aagccaacca gtttttagca gtagcaattg ctatggcact tgtgtatcca
     8161 gctatcacag cagttgctgg tgcgggagaa gctatcagtt tctttgggat cccagtgatt
     8221 ctttcaccat ctggttatac ttcttctgtc ataccaatca ttctagccgt atgggttcaa
     8281 agtaaattag agccattcgt aaaaaaagtg attccgcaat ttctgcaaat gattttagtt
     8341 ccgcttgtcg ttttagtagt gatggttcca ttaacatttc ttgctttagg accaatcggg
     8401 acggttgccg gtaatgcttt aggcggtctc ttcaactcga tttatggatt tagtccaatc
     8461 gtagcaggtc taatcatggg aagtttatgg caagtattcg tgatgttcgg catgcattgg
     8521 ggattcgtac cgatcatgtt tttgaatatc gaacaatatg ggtttgatgt attgatgcca
     8581 atgcttcttc cagccatctt ggcacaaggt ggggctgctt tagctgtagc attgcgaaca
     8641 aaagatacga aacttcgagc attagggatt tcttctacag tgacttcgtt atttggaatc
     8701 actgaaccaa ctgtgtatgg tgtgacatta cctttgaaga aaccattcat tgccgcttgt
     8761 atttctggag gtattggtgg agctattatc ggattttccg gagtaaaagc tttctccagc
     8821 agtttggtca gcttattgac gattccgact ttcattaata cggtggatgg tgtagagtca
     8881 aatgtgacag tagcagtaat agctacagga attgcttttg ttcttgcatt cgtaggtaca
     8941 ttgattttag gatttgacga acaaacacaa gacaatcaat tagaaaacaa acatgcgaat
     9001 gcaggagaac cgattacttc agcacggcat accttaaaaa gtcctttaac gggtaaagta
     9061 ctgccattga gtgaagtacc agaccaagtt ttttcttctg gcgtgatggg aaaaggtatc
     9121 gctattgatc cagaagtagg agaactagtt gcacctgcag acggagagat cacgactatt
     9181 tttccaactg gacatgctgt agggatcaca acgactgacg gagcggagat tttgattcat
     9241 atcgggatgg atacagtaga attaaatggg aatggctttg agatcttagt caaacaaggg
     9301 gatctcgtca aagcaggaga tttattgatt cgttttgaca tcgaagcaat tagagcagct
     9361 ggctatagcg taatcactcc agttgtcatt acgaatactg atgcatttgc cgatatactt
     9421 gaattagacc aaaaagagat tattgcaaac gaagatgttc tggcaattgt aaaataagga
     9481 ggaaatcagg atgcaatcac gtttttcaga aaaattttta tggggtggag caactgctgc
     9541 caaatcaatt agaaggggct tatgatcgag acggaaaagg actatccgtt gcagatgcta
     9601 tgcctggagg taagcagcgc tttgcgatta tcggcagtga agaatttgac tggacgattg
     9661 atcaagaaaa atatatttac ccgaatcatc gaggaatcga tcattacgat cgtttcaaag
     9721 aagatcttgc cttgtttgcg gaaatgggat tcaaatgtta tcgtttttcg attgcctgga
     9781 cacgaatttt tccaaatgga gacgaaggta ctcctaacga agcgggatta gaattttatg
     9841 atcagctgat tgatgagtgc ttaaaatatg atattgaacc tgtgatcacg atttctcatt
     9901 acgaaatgcc tcttcatttg gcaaaagaat acggtggctg gaaaaatcga aaactgatcg
     9961 acttctatga acgatttgct cagacagtat tagagagata cagcagtaaa gtcaaatatt
    10021 ggatgacttt caatgaaatc aattcggcct ttcactttcc agctttaagt caaggattag
    10081 taaaaagcaa tggagcagga gagtaccaaa atattttcca agcatggcat aatcaattcg
    10141 ttgcaagtag caaagccgta aaaatcggcc acgaattgcg ttcggatatc caaatcggct
    10201 gcatgattat ctatgcaaca acttacagca tcgatgccaa tccagtcaat caggcagcaa
    10261 caatgatcca aaaccaagaa ttcaattttt tctgcacgga tgtccaagta cgtggagaat
    10321 accctgcata cacagcgcgt acccataaaa aatatggagt cgatccggaa aaattagagc
    10381 aaacggaaaa agacttccag ttgctaaaag aatatccagt ggactacatc ggatttagtt
    10441 attatatgtc tacggcaatc aatgagactg atccacaagc agcaacttca gaagggaact
    10501 tgctgggagg agtaaaaaat ccgtttcttg aggcaagtga atggggctgg cagatcgatc
    10561 cagaagggct gagaatcgca ttgaatgaat tatacaatcg ttaccagaaa ccattattca
    10621 ttgttgaaaa cggtcttgga gccattgatc atatggaaga ggatggcacg attattgatg
    10681 attatcggat cgattattta cgtcgtcata tcgaagcgat ggctaatgca gtagcagacg
    10741 gtgtagattt gatgggctat acgccttggg gatgtatcga tcttgtcagt gcatcaacag
    10801 gagaaatgag taaacgttac ggctttatct atgtggatct agacgatgaa ggaaatggga
    10861 cactgaatcg atcaaagaaa aaatcttttg attggtataa agaagtaatt gcctcaaatg
    10921 gcgtaaactt gtaattaaag cagctgaatg aaaaagaaca cacttctcac atgtgatttg
    10981 tgttcttttt ttatttttta tgtgctattc ttttagtaat agtaaagcaa agggtgacgt
    11041 tatgaaaagg acacgtgtac tatacttgga agtcgcagat aaaattaaag aagatatttt
    11101 ctcaggaaaa tatccagtcg gttcgatgtt gccgacagaa agtgaattag aagaactgtt
    11161 tcaagtcagc aaaatcactg tccgaaaggc aatcgaactg ctggcatcag atgaatatgt
    11221 cgcaaagaaa agtggtcgtg ggacgacggt tctaagcaat cgtccttaca atcgattatc
    11281 caaagcggca agctttacgc aaatcttgga gaactcccga tatgaagtcc ggaaagaaac
    11341 gctggatttg caattggtcc atataaagaa ggaagatcct ttgttttcct ttttcggtga
    11401 gcaagctgtt tgttttaagc gcttatatta tttgaacaat cagccttata tttattttgt
    11461 tcattatctt ccacaagaaa tgatgcaatt cagcagagaa gaatttggca aagaatcttt
    11521 gtatcgtttg ctgacgaaaa aaggatatac tattgactca ttttctgatg atttctcggc
    11581 agtattttta acagaagaag aacaaggaat tctgaaaaca gacgcacaga tcggcatcaa
    11641 acggatacgg aaatcgtcta cgcaaattgg ggaaatgatt gaatattcgg aggcggtcta
    11701 ccatacggag ctgcatcctt accatattga ttatgaaaca taaataaaaa aagaggttgt
    11761 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagct tctcatattt
    11821 ttcgtttggt taggcttatt accgcagata cacggctgtt tctggattac catttattct
    11881 ggataagggg gtgtggcacg attttcagaa ggaatctatg aaccaatcac tgtattgatt
    11941 ttagcttcga tggtaacccc attcggcttg acgatcgctt atttcttagg gaaaatcatt
    12001 cgtaaaaata tactcaatcg tcaagaaatc gatacattga agaccgcttt tcctatgggg
    12061 atctgtcaga tcacagaggg atgtttccct atcgtattga acgacttggc acgcaatgtc
    12121 atagcaacgg gagtcggtgg gacagtaggt ggcggattaa gcatgttttg gggcgcagat
    12181 agccgtattc cggcatcggg aatgtttgca gtcgctacga tgaccagacc atgggcattc
    12241 attggtgcat tgttagctgg ttcttttgtc acaggaataa ccattttatt attgaaaaaa
    12301 ccagtagatc cgaatgcaga aatcatccaa gaagaaaaag aggaagaaga catatcttgg
    12361 gatgatttga caattagtta ggagaggcag aatggattac aagaaaaaag tacaatagat
    12421 gtaccttgag acaggaatgg tatgaaagaa tcagagttag aaagaatcga atatacagat
    12481 tttggtttag gagcgatcga aactgtccag agcatcggca ccctccttga aatgacgatg
    12541 aaggaaaaat gagaaccttt cgttgtcgaa agggtctggt ataccttatg tcgaaggaaa
    12601 ggaaacaaaa aaactttcct gtactattcc aaaaaggaaa gaaagttatt atacagtaaa
    12661 aaaagaaatt attcttcatg ctagagatca gtacacgttc gagcccaata tcaaacacta
    12721 gttccaggca ggcgcaacag gtgcggttat cactgaattt tcttccagca gtgacgattc
    12781 aagtgatatt tttacaaatc cagctattta tcgttaacaa aaagattttt aggagaagct
    12841 gatgaacaaa aatgatcaaa ttttgatcgt ttagttcgtc ggctttttta tttagagaaa
    12901 catcatttat cagtgaaaca taacacgaga acaaaatgat tttttcgtta ataaaagaaa
    12961 caagtatttg ttgtttaaaa taatacacgt tattggcata taggacgaaa tcccagtatc
    13021 ttctataagt aagtcatttc atatcgatga aaacacgtta tttatttttg ttttatctat
    13081 aaaatggctg aaaaatgatt tttttctaaa tactatatat agtggcgtct atcctatata
    13141 ccactaaaaa actacaaaat ctagtctttt attttaaaaa aacacgtgta gaatgaagat
    13201 agacttttga gttagggagt gtttttttat gaaacttact gttttttgcg gttcccgttt
    13261 tggtaataaa gaaagttaca aatttattgc gcaaacgtta ggaaaataca tggcacaaga
    13321 agaaatcgaa ctggtttacg gtggttcata ctccgggatt atgggagtga ttagtaaaac
    13381 agtactggaa aataacggaa aagtcacagg tatctatccg aatgggcttt ttgaaactga
    13441 attgcctgga aaagatgtta ctacatttat tcctacagaa acgatcgatg aaagaaaggt
    13501 attattattt gaaaagggag atgctgtcct cgttttccct ggaggtctag gtacattgga
    13561 ggaattctca caacttcttt cttggatagc aatcggtctg acgcccgaca agccaatcgg
    13621 aatattgaat attggcggtt attacagcgg cttgcaacaa ttattagaaa cttttgcaaa
    13681 agaggatttt atggataaaa aatggttgga tcaagtaatc ttttccaaca atccattgga
    13741 actggtcaat gaattacgag cagtatctat taaaaatcag ttattattga aggaggcaaa
    13801 ataatgagtc aaatatattt agcaggacca tttttttcag aggagcaaat cgatcgagta
    13861 agtcgtatcg aaaaagcgtt ggaggaaaac aaaacagtca caagtttcta ctctccacgt
    13921 catcaccaag aaagcaatta tgaactattc agcgctggat gggcgcagga agtatacgaa
    13981 aaagatatgg aagaactgac aaatgcagaa tttgttgttg ctatccttga ctttgagcat
    14041 caaacaatcg atccaggaac ggcttacgaa ttaggtgtgg caactatgtt gaaaaaaccg
    14101 atgatcattg tacaagaaga gacggtacct acgaacttga tgattacaca aagtctccat
    14161 acgtatttaa aatcagacca agctgtacgt gaatatgatt ttgaaacatt gcctgttgaa
    14221 acttacgtag gcgagtactt atagaagagg aagggttgta tgtcagtgat tttgatttca
    14281 ggaacgattg gtgcaggtaa gagcagtttg acggatatgc ttgcaaaaga gattgattct
    14341 aaaccatttt atgaaaatgt cgaagataac gaagtattgc cgctctttta ttcaaatcct
    14401 gagcagtacg cttttttatt gcaaatcttc tttttgaaca agcgattttt agcaatgaaa
    14461 aatgctttag tgaacgatga caatgtgcta gaccgatcca tctatgaaga tagcctgttg
    14521 ttccatctaa acgctgattt aggtcgggta acggatatcg aagtacagca gtacgatagc
    14581 ttattagata cgatgctaaa cgagttagat gatgttgctc caaaaaaacg gcctgatttg
    14641 atggtccata tcaaagtttc tttggacacg atgctagaac gtatcaaaaa acgtgggcgt
    14701 gactatgaac agctagaaag cgatgagacg ttatatacct attatgaaac gttgaacacc
    14761 cgctataatc aatggtatga agattttgat gtatgtccta aaatacaagt ggatggggat
    14821 aaattcgatt ttgtagaaaa tccagaagat gcaaaaaagg tgatccgtca gatccaagaa
    14881 aaattagctg aattggaagg aaagcctgct ggaaaatatt ttacggataa ccagcatgca
    14941 aaaggtcaag aattaggcta aaaataaaaa accaaacgac gggaaagaaa aatt
//
LOCUS       DAIGSZ010000068        13976 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.069, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000068 DAIGSZ010000000
VERSION     DAIGSZ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13976
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.069"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            174..518
                     /locus_tag="NOB31_002282"
     CDS             174..518
                     /locus_tag="NOB31_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HCI0974468.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            519..938
                     /locus_tag="NOB31_002283"
     CDS             519..938
                     /locus_tag="NOB31_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCI0974469.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1030..1380)
                     /locus_tag="NOB31_002284"
     CDS             complement(1030..1380)
                     /locus_tag="NOB31_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974470.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1346..2667)
                     /locus_tag="NOB31_002285"
                     /pseudo
     CDS             complement(1346..2667)
                     /locus_tag="NOB31_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
     gene            2923..3489
                     /locus_tag="NOB31_002286"
     CDS             2923..3489
                     /locus_tag="NOB31_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0974471.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3634..3721
                     /locus_tag="NOB31_002287"
     tRNA            3634..3721
                     /locus_tag="NOB31_002287"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3666..3668,aa:Ser,seq:cga)
     gene            complement(3773..4978)
                     /locus_tag="NOB31_002288"
     CDS             complement(3773..4978)
                     /locus_tag="NOB31_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0974472.1"
                     /translation="MAKKEIDKRIKKHLTKKGEEKYQFSLYLGVDPLTGKKRKTTRRG
                     FSTPLAAERALKRLEADIQEKGLQASTAQKSKKFEYVYGLWFENYKKTVKESTWSSTK
                     QIFDTHILKVFGDKFIDKIDVFFCQEAVNTWSDSHPKIFKKIKNYTSNVFDYAASLQI
                     ITSNPMKLVSIPRGEALDIEDKNIEFYTKEELIKFLEAIRNDDDERYLFFSLLAFTGI
                     RKGEAFALTWSDIDFKSKTLNINKTVTRGYQGRLIVNTPKSKSGKRKIYLDNDLISLL
                     RKYYTKNKTIVTIQRENLIFHHDGLLYNPTVSRSWLNVIYKHHPELTKRITTHGFRHT
                     HASLLFESGASLKDVQERLGHADIQTTSNIYTHVTETQNKKVINNFVAFMKNSTQGES
                     KGESKNILG"
     gene            complement(5116..6004)
                     /locus_tag="NOB31_002289"
                     /pseudo
     CDS             complement(5116..6004)
                     /locus_tag="NOB31_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            complement(6091..6291)
                     /locus_tag="NOB31_002290"
     CDS             complement(6091..6291)
                     /locus_tag="NOB31_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974473.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRKVKKAVIPGYGKKGSGWIKD
                     PKKAAYNKVYKKTTFSFWDLFK"
     gene            complement(6320..6742)
                     /locus_tag="NOB31_002291"
     CDS             complement(6320..6742)
                     /locus_tag="NOB31_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCI0974474.1"
                     /translation="MYLPQIDNKINKLVKLYQTRNPFRIARELKILVLEEDLGEIYGY
                     YSKFKQIKMIHINSSLDEMGKWITCSHELGHCVLHPNENTPMLSKKTLVSELKIEKEA
                     NYFATHLTIDPTLDGFDHMTKYEKLVCFGLPDEFDRFL"
     gene            complement(6759..7181)
                     /locus_tag="NOB31_002292"
     CDS             complement(6759..7181)
                     /locus_tag="NOB31_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0974475.1"
                     /translation="MTTFERIKELAKNKNKNLQQVAKDLKYGENYFYSLNAGKQPTAE
                     KLQEIADYFDVSVDYLLGRTEKKRYYDLTEKDERDIQKELQSLIDDLSNADGMAFSKK
                     DNEMSEATREALIISLENALRIAKIEAKKKYTPKKYRD"
     gene            7472..7663
                     /locus_tag="NOB31_002293"
     CDS             7472..7663
                     /locus_tag="NOB31_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974476.1"
                     /translation="MSNLDNGRAAIKEFMKENGITMDDLATAYGHTRVRMQQILDGHW
                     SGPKANRTILEIIRDYRIR"
     gene            7674..7940
                     /locus_tag="NOB31_002294"
     CDS             7674..7940
                     /locus_tag="NOB31_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974477.1"
                     /translation="MNILSEEFLTRLRIAIVEVVKDALSQLSKKNLSETRYLKKIEAR
                     KYVGGVNDQGFEKLIAHGLKEIRIDGFLRYDKKDIDELMAKYKI"
     gene            complement(8181..8660)
                     /locus_tag="NOB31_002295"
     CDS             complement(8181..8660)
                     /locus_tag="NOB31_002295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974478.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            8705..9412
                     /locus_tag="NOB31_002296"
     CDS             8705..9412
                     /locus_tag="NOB31_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HCI0974479.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFDKKHRHVLTAIDELKEGVAEN
                     WADLFWEDTYVHPQNKQSYRIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKE
                     LKDQLPSIPATKREMALLALAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMV
                     RNKIRVICNQQHLNSKAKAELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMP
                     STATMTIIKQMELLEDE"
     gene            9591..9932
                     /locus_tag="NOB31_002297"
     CDS             9591..9932
                     /locus_tag="NOB31_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974480.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            9925..10671
                     /locus_tag="NOB31_002298"
     CDS             9925..10671
                     /locus_tag="NOB31_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HCI0974481.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            10677..11363
                     /locus_tag="NOB31_002299"
     CDS             10677..11363
                     /locus_tag="NOB31_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974482.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            11370..12203
                     /locus_tag="NOB31_002300"
     CDS             11370..12203
                     /locus_tag="NOB31_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HCI0974483.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            12220..13071
                     /locus_tag="NOB31_002301"
     CDS             12220..13071
                     /locus_tag="NOB31_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0974484.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            13068..13427
                     /locus_tag="NOB31_002302"
     CDS             13068..13427
                     /locus_tag="NOB31_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HCI0974485.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            13442..13603
                     /locus_tag="NOB31_002303"
     CDS             13442..13603
                     /locus_tag="NOB31_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCI0974486.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERIKAVMVNETARKAINLHIVNL
                     RREIRRLEE"
     gene            13606..13905
                     /locus_tag="NOB31_002304"
     CDS             13606..13905
                     /locus_tag="NOB31_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974487.1"
                     /translation="MGKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
BASE COUNT         4877 a         2265 c         2689 g         4145 t
ORIGIN      
        1 aaataaaaaa agcgttagca actatgctta aaaagcatat cgactgaata aactaagcat
       61 tggacaggct gaaagactac atttaaaatg aaatgcgaag aaacaataga aaataaagtt
      121 gccttagaac catagttgaa tcacctaaca gtcgtgaagg gagaataaga gaaatggcag
      181 aaaaacaaac cgcaggacga gatcaattag gagattttgc accaaaattt gcagaattga
      241 atgatgatgt tttatttgga caagtatggt ccagagaaga attatctgct catcagcgta
      301 gtatcatcac catatctgca ttaatttcag gaggaaattt tgaacaattg ccagctcatc
      361 tgaagattgg caagcaaaat ggcattacta gtgaagaaat agcagaaatc attacccatt
      421 tagcttttta tgtaggatgg ccaaaagctt ggtcagcttt tagtttagca aaagaaatct
      481 atttagaaga aaatagcgaa gataagaaag aggcgtaaat gacgacaaaa cacgaagaaa
      541 tacacaatgg cgtgattttt ccagcaggtg aaaaaaacga agcttacgct caagtattta
      601 ccgggcaaag ctatctgaat atgttagtga atgatcccga agtttctgtt ggtgtaggta
      661 atgtaatttt tgaaccaggt tgtcgcaatc actggcatgt ccataaagac ggctatcaaa
      721 tcttacttgt gaccggagga gaaggctggt atcaggaaga aggaaagcca gcaagacgat
      781 taatggctgg agatgtcgtc gtaacgcaca aagggattaa acattggcat ggtgcgacaa
      841 aagacagttg gtttgaacat ttggcgatca ctgctggtaa ttcagagttt ttagaacctg
      901 taacagatga agtgtatgaa ggattggaaa atcaataatg tcaagcttga acagctcctg
      961 aaagtagatt ttaatcgaac tttcaggagc tgcttttttg attcagtctt ttataaatag
     1021 aaaatagggt taataatagg aatgagaagc acgtcgaaag atcttaatat tgataatcgg
     1081 ctgggcatac atgatttcca cgtcatcaat caaactacct aacagatgat aatcttcccg
     1141 atcatgtcgg ggattaccta atagttcttg atagtagatt tccatactag ggtcccgagg
     1201 attgttcagc aaatcagcaa gtacatctaa atcttctggc tgagtttctg ccgtaccctg
     1261 tatctctatg aaaagccctt cctcagcaaa ttctactcca atacgtattt cagttatttc
     1321 atgggaatat aaataagtaa gaagctcatc gatgattctt tttgataatt ctttttccaa
     1381 gtgtcttttt ttcctttctg acagcggtaa agttatctag tatcggtaca aggatacctg
     1441 caacgaaacc agttgaaaaa ccactgttat atagatttag tcctccgtgc aaagtgctga
     1501 cgttatggac aagagcaata tgtagtacac cagctattac accgtaaaaa ctgccgtaaa
     1561 aaccgcttat gggcgcgaga cctgtcccaa acacagctgc aacaagcatg ccagtactgg
     1621 tgatctcatg aaaagttcca aacaaagaag caataaatat tccgactagt atcggaaaac
     1681 tgttttttaa atgacaacca aaagcactga aacccaccgc agataaaata gcaccgatga
     1741 caggtccatt taactgaccg ccaaccagca aaacataaga agacagcatc agaccaacta
     1801 agcctatgtt gatcaaagta gcaccaatac cagaattagc aatgaaatca gttgtcaatt
     1861 ttccagatga atcgaaaatt tctcgaatcc ccaaaagccg aaaggaatta taatagaaac
     1921 caattccgac tgtcagcgaa aaaaagccaa aaataatcca aatgagagga aagtgatatt
     1981 cattgaaaac caatgtattt tcgacgattg aatagctgaa taacctcaaa acagcagtaa
     2041 aagtcatcgc aatcaaccca gaggtgaatc caatattata aagtgtgaat ccacgatgga
     2101 aaactaaagt ttgagcagct aagggcggaa gaagtagacc aattgctatg ccagctaaat
     2161 tccccaataa aatacctatc agtaaaggaa aacgcatacc aaaagtgata taactaacga
     2221 ccggtgataa tgcgctacca aacagtccga tcatgatgta ctgagaaaaa ggtttattga
     2281 caaatacagc gtatagatac acacctaaaa tgattgagat agaattataa aggtttttgc
     2341 caaaaaaaga gaaaccagaa tcgaagcaaa taagggaccg tttaaaatca ccttgtgccg
     2401 ataagctaaa agcacagaaa gtaaggtcaa aatccctaca tttatgaatg cgcttccgaa
     2461 accgcctaaa gcaaaataat ctgtcaaaag attgcttggc gaggtaagaa tagttagcaa
     2521 tccactccaa ttatcagtag gagtattaga aagcaagcca ataaaaagaa aaaaaacacc
     2581 tgtaaaacca agataaaaat actttctttt ctgtgaaacg attcgttttt gaggatgaat
     2641 ataaataacg tcagtttcgt tttccattac acaccttctt tttcattttc tttaactata
     2701 acttgaaatg aaagatttgg acaactatca tttaggtcaa aactaaaaat gtaagggaac
     2761 ccattgaatt taaccaaatt tttttaattt tgcaaaaaaa agttaaagaa gactgaaaaa
     2821 aaatttaaaa tataacgttt tgagtaaaat gtttgcaaaa aatgctaaaa atagggtaca
     2881 ataaaacaac atatactgca gtaaagaagt gggggagttt taatgagaag aaaagtctat
     2941 accaaggatc aaattctaaa agctgcttat gatgttgttg caaaggaagg gtttaaagga
     3001 tttactgcga gaaatattgc taaaaagatg gggatttcga cacagccgat ttatctggaa
     3061 ttcaaaaaca tggaagattt aaaaaatacg ttgctggatt ctatctttga acaactaaaa
     3121 gaagatgttt tccctattga acgtactggt gataaaatca ttgatctcgg tttgaactat
     3181 atctactttg caaaaaagca tcatagtctt tacatggcat tgtacattga tgaacatggg
     3241 gacggaaaga aaatgcatga tttttcatac aattatttcc gtgaaatagt taaagaagat
     3301 gaaagataca atcaattatc ggatgaatat gtcgatgctc tgcatactgg tacatgggta
     3361 gcagtgactg gcttagcgtc attgatgtca tcaaacatca tgcatccaac agaagaacaa
     3421 atcattgcac tgatcaaacg gacaattgac tcgattttag cattagataa tcctgaaata
     3481 atcagatagt gttctatcag tatgaatttg atcggtaagt ccgttggctg caaactgtca
     3541 atggactttt ttgctaaaaa aagcgatttc tgttatttat ctattagaaa taggcttgac
     3601 atttcgtgaa aaaagtttaa aaatagtact tacggaaggt tggcagagtg gtaatgcacc
     3661 ggactcgaaa tccggcgaac cggctaatac cggcgcgcag gttcaaatcc tgtaccttcc
     3721 ttatatatca acgattagac acgatttcga tcgtgtcttt tttgttgtat atttagccta
     3781 aaatgttttt tgactcccct tttgactccc cctgagtact gttcttcata aatgctacaa
     3841 aattattgat gacttttttg ttttgagttt cagttacatg agtgtaaata tttgaagtag
     3901 tttgaatgtc tgcatgccct aaacgttcct gaacatcttt taaagaagct cctgattcaa
     3961 aaaggagaga ggcatgagta tgtcgaaaac catgagtagt gattctttta gtcaattctg
     4021 gatgatgctt atatatgaca ttaagccacg aacgtgaaac tgtagggtta tagagaagac
     4081 catcatggtg aaaaattaag ttttcccttt ggattgtaac gatcgttttg ttttttgtat
     4141 aatactttct caataaactg atcaaatcat tgtccagata aatttttctt tttccagatt
     4201 ttgatttagg agtatttacg atcaatcttc cttgataacc tcttgttaca gttttattga
     4261 tattgagtgt tttgctctta aagtcaatat ccgaccaggt cagagcaaaa gcttctcctt
     4321 ttcttatacc tgtaaaagcc aatagggaaa agaataaata tctttcatca tcatcgtttc
     4381 ttattgcttc taaaaatttg attaattctt ctttagtata aaattcgata tttttatctt
     4441 cgatatctag agcttctcca cgtggaatag aaactaattt cataggattg ctagttataa
     4501 tttgtaaaga agcagcgtaa tcaaaaacat tagatgtgta attttttatt ttcttaaaaa
     4561 ttttaggatg gctatcggac caagtgttta ctgcttcttg acagaaaaaa acgtctattt
     4621 tgtcaatgaa cttatctcca aacactttta agatgtgtgt gtcaaaaatt tgtttggtgg
     4681 aggaccaagt gctttcttta actgtctttt tataattttc aaaccataag ccgtaaacat
     4741 attcgaattt cttgctcttt tgagctgtag aagcttgcag tcctttttcc tgtatatctg
     4801 cctccaatct ttttaaagct ctctcagcgg ctaatggcgt actaaaacct cgtctcgttg
     4861 tttttctttt ttttcctgtt agaggatcaa ctcctaagta cagactaaac tgatattttt
     4921 cttcgccttt ttttgttaag tgctttttaa ttcgtttatc aatttctttt tttgccatct
     4981 ttatctttcc tttcgtacgt ttgttcggtt gtacagcgga tttcgagatg gtaaaatagg
     5041 gtacaacaaa tagacctact ttaccgtagc tctttgcaca tttgcgttct tggtcgggcg
     5101 gcaaatgtgc tttttttatt tcactcttag ttcttgtcct ggataaagca tgtagttgtt
     5161 tggatccata ccgtttaatg caaacagttg atctaccgta attccagctc gttcagctat
     5221 ttgtttggtc ccttcaccag gttgcaaagt caaggtttcg gtttcagatg aagaaggtgc
     5281 cgttggttga gcttgattag ctggtacata atcttgtggt actgattgct ccgttgaact
     5341 gggagtgggt gaaacttgtt caacacttga actaggagta gcttctgcat agttttctac
     5401 actttcagca gagtaagtac tactagtttc aggaggcgta ttctgcgcaa tagcagcttg
     5461 ttctacagta ctagaagatg caatagtact ttctgttgta gtcgaagatg attgttcgtt
     5521 gctacttgtt gagctagtag ttgttctaga ttctttagtt tttttccttt ttgtagggtt
     5581 tcaaaactaa tttctcatta tcatcagatt tgttaggctt ttctggagtt aaaataatat
     5641 ttttatcttc tttgctgaca gtatatttgg catcattatc tttgtcttta tcatctttcc
     5701 aagtcataac atcgccttca agtgtatact caaatttgta attcatttgg tcgactaagc
     5761 ttttagcaaa ttcttctccc atagcctccc aatcgttact tgaagttgat ttcatagaac
     5821 ttgtgtcaac actaaaagat acgacgtgat cagaaaatga tacgatcata ttaggttcgt
     5881 catctttggt tgcttcaatc aaccaatcat tagcttttaa atcttctgta gttacttttt
     5941 taccacaagc agtgaaaagt aacagagaag caaaaactaa taaacttgtt attacttttt
     6001 tcatttttta ttcctcattt ctatgatatg atttttattg gggaatctta gaaataaggt
     6061 ttcgagtccg tgttgctgca cgggcttttt ttatttaaat aaatcccaaa aactgaatgt
     6121 agttttcttg tatactttat tgtaagcagc cttttttggg tctttaatcc agccgctacc
     6181 ttttttccca taaccaggaa taactgcttt ttttactttt ctttttgctt ttccagtggt
     6241 tctagcgctt atggattttt ttatacttgg ttttctcatt cctattttca tctatatcct
     6301 ccttacgttg tattataatt cacaagaaac gatcgaattc atctggtaat ccaaagcaga
     6361 cgagcttttc atattttgtc atatgatcaa agccgtctaa agttggatca atagtcagat
     6421 gagttgcgaa ataatttgct tctttttcaa tttttaattc agatactagc gtttttttag
     6481 acaacatagg tgtgttttca ttcggatgca aaacacagtg gcctaattca tgactacaag
     6541 ttatccattt tcccatctca tctaaactag aatttatgtg gatcattttt atctgtttga
     6601 atttactata gtaaccataa atttctccca aatcttcttc taaaactagt atcttcaatt
     6661 ctcgtgcaat tctaaaagga ttgcgtgttt gatatagttt taccagctta ttaattttgt
     6721 tatcaatttg aggtaaatac ataaacaacg tactcctttt aatcgcgata ttttttaggt
     6781 gtgtattttt tcttagcttc tattttagct attcgcaaag cattctctaa agaaataatg
     6841 agagcttcac gtgtcgcttc actcatttca ttatctttct tcgaaaaagc cattccatca
     6901 gcattagata aatcgtcgat taatgactgc aattcttttt ggatatcacg ctcgtctttt
     6961 tctgttaaat catagtatct ttttttctca gtacgtccta gcaaataatc tacagatacg
     7021 tcgaagtagt cagcaatttc ttgtaacttt tcggcagttg gctgttttcc tgcgtttaaa
     7081 ctataaaagt aattctctcc gtacttcaaa tctttagcga cttgttgaag gtttttattc
     7141 ttgtttttcg ctagttcttt tattctttca aatgttgtca ttccaacgtt cctttccaac
     7201 acgaaaaaat aatttacgaa aaagagtaaa aatagcttta caattttacg atatagagtt
     7261 attatttatc cgtaagttaa tttgatagaa aaaagcaaac taaaaacaca ccttatagca
     7321 taaagtttgg cgaccaagtg caaataaaag gttttgttat aggcttattt ctctatgtat
     7381 tcattttact ctatagtgta aaaatgtcaa tggaaattat attttttcta tcattttaac
     7441 ttacaaattt ataaaaaaag gaagtgggtt aatgtcaaac ttggataacg gtcgtgcggc
     7501 gatcaaagag tttatgaaag agaatggaat aactatggat gatttggcta ctgcttatgg
     7561 tcacacgcgt gtacgaatgc aacaaattct tgatggacac tggagtggac caaaggcaaa
     7621 cagaactatt ctagagatca tccgtgatta cagaattcga taggaggcaa gtcatgaata
     7681 ttctaagcga agagtttttg actcgtttaa gaattgcaat tgttgaagtt gtaaaggacg
     7741 cacttagtca actttcaaaa aagaatttgt cagaaacacg atatttaaaa aagatcgaag
     7801 ctagaaaata tgtgggaggt gtaaacgatc aaggttttga gaagttaata gctcacggtt
     7861 taaaagaaat tcgtatagat ggctttttaa gatatgacaa aaaggacatc gatgaactga
     7921 tggctaaata caaaatttaa aggaggtcaa catgggaaag tttaatcgaa cattagtatt
     7981 cagcgcgcca ctaattatct acgctttagg tctatggggt agtagacaag cattaatcgg
     8041 cacgatcgtt tacatgcttt ggattttcat tgggcttgat gaagctgagt acagagcgaa
     8101 aaagccagtc gggagggact gactaaaaaa gtctaatgtc tataagaaag gtttgacaat
     8161 aaatgaaaga attatttttt ttaataactt tcatcatttt ttctatcagt gttttctaca
     8221 ttaacctttg cgttgctaga tttgctttga aaagttttag gaacagcaaa cgaaaataga
     8281 gctataaaag atacgaatgt agtagctacg ttaaattgct ctttagaaaa cgtcaatgtc
     8341 attggaatga taattgatat cgatgagaaa atctttgcga taataactat ccatttttca
     8401 attataaaca tttttaaatt aagcaccatt agacaaaatg tagttcctat atagaggata
     8461 aatgaagata gaaataaaca tattagtcca gttttaaaaa aagagaagta atctatgtgg
     8521 gcaaattctg ttaatatgct tttttgattt aacacaatca aactactgtt ggacaaaaat
     8581 gacagtaagg aaagagttgc tccgattact aaataaaaaa tagttgttaa caatattata
     8641 ttatcaattt ttctgctcat gttttcaccc caccagaatt atatcaaaaa ggagagaaga
     8701 aataatgcaa gaattagtaa ttttgaaaaa taaagaagct gtgactacga gcttacaagt
     8761 tgcagaaagc ttcgataaaa agcacagaca tgttttgacg gctattgatg aactaaaaga
     8821 gggggttgcc gaaaattggg cagacctatt ttgggaagat acttatgttc atcctcaaaa
     8881 taaacaatca taccgaatta tttatatgaa tagagacggc ttctctctat tagcaatggg
     8941 cttcactggt aagaaagctt taagttttaa acttcaatat attgaggcct tcaacaagat
     9001 ggaaaaagaa ttaaaagacc aattgccatc aattccagca actaaacgag aaatggcatt
     9061 acttgctcta gctgcaaacg aagaaacgaa tgaaagagta gacgctatcg agtctgattt
     9121 aaacgatttg aagaacaatc aacttctagc tgaaccagat taccgaacaa tttctaatat
     9181 ggttcgcaac aaaattagag ttatttgtaa tcagcagcat ttaaatagca aagcaaaagc
     9241 agaattgttt aaagacttga atggcggaat taagcgaatc actggagcag tagctagaaa
     9301 tcgtatcaag gcaaaacagt tcgatgatgt tatcgatttt attaacaatt ggatgccttc
     9361 tacagcgacg atgacaatta ttaagcaaat ggagttgtta gaggatgaat agagctgaag
     9421 cgctaaaaat aggcgtaata attgctaatc gctggtggag acacaataaa ccaaacatcc
     9481 taagccaaca acatattgat aagcaaaaag catggcaaca aataaaaaag tgactcagcc
     9541 gaccaaagca atgagtcaca aagaaaatac atctaaggag atgttaccac atgaaaaaag
     9601 aactttccac tctagatcaa tatttgactg atcctagttg gggcaaatcg aatatcaagg
     9661 aaacaagcaa tcgaaaaatc agacgtaatc ttttgacgga tgaagaacta gcatgtgatc
     9721 aagacgattt gggaaatttt gtgagtattt gggatcatgt ctatcttatc catttatcga
     9781 ggaagtccaa aaaaactgaa tatatctatg tcatcgaaga tggcttgatt gatgcgctag
     9841 aagagtatga cagagataac ttgattgata tctcttatta cggatcaggt aagaaataca
     9901 ttgctgaaat ggaggcagaa tttgatgagt gaaaaggaac aacctttgaa aaatagaagt
     9961 gataatacgc tttttaatac cttatacaaa ataaatgtga aagatgttac tgaaaaacga
    10021 aataacctca cttatctttc gtgggcatgg gcttgggcag aagttagcaa agtgtgtgag
    10081 gcagtagatt atgaaatcta tcatgatcca gaaacatatc tgccgtatgt ctttgataag
    10141 aaaacaggct atatggtttt taccagtatc acagtcaacg gagtaaagcg tgacatgtgg
    10201 ttaccagtca tggatggtgc aaacaaggca atgaaagatg agccatatac ctacgaagtc
    10261 aatgattatc agtggaataa cgaaacgaag aaaaaagaga ttgttggaaa aatcgaaaag
    10321 cgagttgaag cagcaactat gtttgatatc aacaaaacga tcatgcgctg tcttgtaaaa
    10381 aatctagcaa tgtttgggct agggctatat atatttgctg gcgaagatat gccagaagat
    10441 gtctcgatgc ttgaaccagc tactcaaaga agcaaaaagc tattcttgga tgctttacaa
    10501 ctggttgcta acaagtacga aaaatcaatt gatgaagcaa ttgttgcatt gactgatgcg
    10561 gcttctataa ccgctgatga cagtaaatgg accaagagag acttgggcat tctaaaacga
    10621 ggcgttaact ggattgaaga tcagtacaga gaagaaacaa aagagaagtg atatgagtgt
    10681 ttaaaccatt gatcgattca tattcagcgg ttctgaaaaa gttcaaagga aaagacatag
    10741 gtgcaacgat caatgaagaa gtgaacattg atcgactaaa gacgatgtat gacggatatg
    10801 atggcgatcg gattattgaa gttcgattta ttgatccacg tcgatttact gtgcagcaac
    10861 gaaacttcat ctatgcgctg ataggcgata ttttcatcga tacaggcatg ccaacggact
    10921 tctggaagga attcttttac ttccgttttg aaggcgtcac agggcgcaaa ataagcctca
    10981 aagacgaatc gaatacaact gtgagtgatg ctaatgtctt agcaaatatc atcttagatt
    11041 tcatctttga acatcatatt cctttcaaag aaggctatga gattttacca gcgaatcaag
    11101 aatattactt ctacaaatgc atcacaaaaa gagtctgctg catctgtggc aaaacaggag
    11161 ctgacatcga tcactttgac aaagcgctag gaagacgaaa gcgcaaagaa gttgatcatt
    11221 cagagtacac atttgcagca ctctgcagga ttcatcacac ggagaaacac aatataggtg
    11281 tgatcaattt caaaaataaa tatcaaatca aagggatcaa gttaaaccag gaaacaatta
    11341 agaaacttag aataggaggg taaaaaatat tgtctgacaa caaacgctac tactatttaa
    11401 aactaaaaga gaattttttc gatagtgacg agatggttct cttagaaagt atgccagatg
    11461 gctatattta ttctaatatt cttctcaaac tttatttaag aagtctaaaa cacgaaggta
    11521 agttgatgtt taatgacagg attccattta actctacaat gctcgcaact attacaagac
    11581 attctgtagg agtcgtagaa aaagcggtac aaattttccg tgatttgcag cttattgacg
    11641 tattagataa cggagcaatt tatatgtctg atatacaaag tttcattgga aaatcctcaa
    11701 ctgaagcaga tagaaaaaga gaatacagaa agaaaataga agaggcaaaa cggaatttaa
    11761 taactggagg acaagtgtcg gacaaatgtc cagacaaaac tacaccagag ttagagatag
    11821 agatagagaa agatatagat atagataaag aagaaaagaa aggtaagtat tctgacgaac
    11881 acttacgcct tgctaaaaaa ttgcaaagta atttaactga agattttcca aaagaaatga
    11941 acaaagtaga tatcgaaaaa tgggcagaca caatcaggtt gatggaagaa agagataaag
    12001 cgtctataga agcgattgag tatgtgatca attggctacc tacaaatgaa ttttggtttg
    12061 gaaatattag aagtgctaag aaattgagag aaaaatttga gaagctcaaa ttcgaaatca
    12121 aagcagacaa gaataatcat aaaaagcaaa gtcaaaaact acagtacagc aatcctagtg
    12181 aatatgacga cttgccaatt taaaaaggag atgcatcaca tggaaagcct agcaaatgct
    12241 atggagaaac taataagaag agtattagtg caaagcggga aatgtccaga atgtagcgaa
    12301 cctttgtata gttggcgagc taaaaataag gatggttcag aacgttgtaa accaacatgc
    12361 atgagttgtg gttataaagc gttacgtgtg aaagaggata tacagaccga acggatatat
    12421 aacgacagct taaaagcacg agcgttgagt ttttttcaaa atggttcggt attaacagat
    12481 aaaactttgt ttaaatgcaa aatggagaat tatcacgtag tggaccaaga aacgaaaatt
    12541 gctttagaaa gagctaaaag ctttgtaaat gatgtcttac tgaaccatcc tgcacatttc
    12601 attctatcag ggaaatcagg aagcggaaaa agccacttgt caatggcgac agcttgggaa
    12661 atacttgagc gctcaaatta tgacaagaaa atacttttta taagctatca agagttatta
    12721 gagcaaataa agttttctta taacaatgct gaactgagaa aagaaattga aggatcgctt
    12781 atagccgata tcaaaacaac tgatttggtg gtttttgacg atattggagc tgaattaggt
    12841 agcggggtat caaatagtag gcagtttaca aacaacacgt taaacacgct cttagaagcc
    12901 agacagaaca aggcaacgat catcacaaca aacttatccg gtcctgaact aagagaagcc
    12961 tacggcgaaa gaattgtttc tagaatattt aagaattcag aaggttatgc gctgaaattc
    13021 caacaaacag cagacaagcg cataaaacca gtgaaaggta gtatcgcatg aataaatacc
    13081 gtaataagaa aactgttcat cgaggtatca agtttgattc tatcgcggaa gcagagtatt
    13141 acgatttagc cttgtggcaa gcagaagcga acggctggaa agtaaaactt caggaaagat
    13201 ttgagctgat gccgaaattt gaactagatg gaaaaaagta tcgcaagatc gagtatattc
    13261 ccgacttcac attttataaa aacggcaaac ttgtcaaagt cgtagatgtc aaaggaatgc
    13321 agacaaaaga ctttaagatc aaggcaaagt tgttctgtca tcaatatcaa gtgccgttga
    13381 tattagctaa aaaatatcgg aatacgttca aggaagagcg tttttaacga ggtggtccat
    13441 catgacaaca gaagaagtga ttcaaatgcg tattcgaagc cttcaacgtg agattgacga
    13501 tctggaacgg ataaaggcag tgatggtcaa tgaaacggcg agaaaggcaa tcaatttgca
    13561 catagtgaat ttaagaaggg aaattcgtag attggaggaa tgagcgtggg taagaaagca
    13621 gcaatgaaac gaatcattga actgacacat tctgagaatt ggcaagaaga caaagaaata
    13681 gttgcagaag tccaaaagct cggtaaatca atgtggactg aaaagcctaa acggaaaacg
    13741 ccgagaaaaa ttgcaatctg gcatggtgat cgaattctag taacgggtac agctgaacag
    13801 ttatctgaaa ttactggact gagcaaaaac atcatctggg atagagctag gagcttatgg
    13861 attgattcaa aggggcgaca gtttaggtat gtggaggaga aataatggat ctcattacac
    13921 aatacagtga tatcatcctc aagaaaatca tgatgaagat tcagaaagat aaaaaa
//
LOCUS       DAIGSZ010000069        13404 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.070, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000069 DAIGSZ010000000
VERSION     DAIGSZ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.070"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(64..606)
                     /locus_tag="NOB31_002305"
     CDS             complement(64..606)
                     /locus_tag="NOB31_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HCI0974488.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            741..1130
                     /locus_tag="NOB31_002306"
     CDS             741..1130
                     /locus_tag="NOB31_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974489.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1134..1898
                     /locus_tag="NOB31_002307"
     CDS             1134..1898
                     /locus_tag="NOB31_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI0974490.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            2027..2974
                     /locus_tag="NOB31_002308"
     CDS             2027..2974
                     /locus_tag="NOB31_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0974491.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3104..3844
                     /locus_tag="NOB31_002309"
     CDS             3104..3844
                     /locus_tag="NOB31_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974492.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(4135..4803)
                     /locus_tag="NOB31_002310"
     CDS             complement(4135..4803)
                     /locus_tag="NOB31_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCI0974493.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            4937..5224
                     /locus_tag="NOB31_002311"
     CDS             4937..5224
                     /locus_tag="NOB31_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974494.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            5640..7178
                     /locus_tag="NOB31_002312"
     CDS             5640..7178
                     /locus_tag="NOB31_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HCI0974495.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            7175..8140
                     /locus_tag="NOB31_002313"
     CDS             7175..8140
                     /locus_tag="NOB31_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974496.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            8127..9449
                     /locus_tag="NOB31_002314"
     CDS             8127..9449
                     /locus_tag="NOB31_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0974497.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      9512..9616
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            9690..10433
                     /locus_tag="NOB31_002315"
     CDS             9690..10433
                     /locus_tag="NOB31_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0974498.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            10448..11440
                     /locus_tag="NOB31_002316"
     CDS             10448..11440
                     /locus_tag="NOB31_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCI0974499.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            11452..12189
                     /locus_tag="NOB31_002317"
     CDS             11452..12189
                     /locus_tag="NOB31_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974500.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            12179..12901
                     /locus_tag="NOB31_002318"
     CDS             12179..12901
                     /locus_tag="NOB31_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCI0974501.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(12985..>13404)
                     /locus_tag="NOB31_002319"
     CDS             complement(12985..>13404)
                     /locus_tag="NOB31_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HCI0974502.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         4416 a         2294 c         2786 g         3908 t
ORIGIN      
        1 aaataaaaac tgtctaacat ttaaaattta atttagatat tagacagttt ttaagtttgt
       61 gagttatttt ccttgtcgtt ttctcacttt tttagtccag aaaccacctg aaatatattt
      121 tggctcataa gaaatgataa aagcacgctc ttcgatttct ttgatcaggc gatacagttc
      181 acgttcgctt tttctaggag aaagtatttc gagaactagc cgctcacctt ccagccccat
      241 tgcagaagtc tgtgtcacac cataaccgtg ttctctcagt atacccggca aacttttatc
      301 ttctgcgcta tttgctggca aaatcgttgt gaccatgatg tatcctaatg ccaatttgtc
      361 ttcaatcaaa attccgacac tgatacctac tgcgtaacct aacgcataga caaataaatt
      421 cagtggatta tctaaacgat ctaaaacaag ggataagccg acgatataaa tcgtgatctc
      481 gaccatactg acaagtggag caatcagtcg atagcctttc attgtcaaca tgaaacgtaa
      541 cgtgttcaga gtgatataag caaaattaat gaggaagatc atccccaaca tttttggatc
      601 aatcatttgt aaaactcctt tcatttatat aacaacaata tcaaaaaaaa tcgtaagtga
      661 agaaaaattg aaactttata catacaaaaa aatgataaaa tgattataat agaattataa
      721 agataggtta ggtgattaaa atgaaaacgg tcaatcgtgt gttttgtgcc agccacgtgc
      781 taagtctcct tctcagtata tacttaggtg tctattcgat tcaacagcca attgaggtag
      841 agaacattgt ttttcagatg tcgctgacag atggtttaat tttaagcgtt tttttctttt
      901 tgatactgtt tattggtaat attttcggta gcgttgccag ttttttgaat ttttctattt
      961 atccactcct ttcgctagca ttaggagtgg tgggactttg ttctctgtgc ttatttcccg
     1021 agccattcag tcctgcattt atattatttg gtacactgaa cctgttccag acaactgttg
     1081 gagcatggtt gctatggcga tcaggaaatt taatgaaaat aggtgagtaa caattgaatc
     1141 caattatatt gaaacgttct gtccatcata ttccagtgtt agaagttgtt ctgaaagaat
     1201 taagagagga acgtattccc gttgtcatct attatcacgg atggcagaca agtaaggagt
     1261 tagttttgac gcaaggaaga aaaattgcgc agcagggcat tcgtgtgatc ctgccagatg
     1321 cgatgaatca tggggagcgc aaacagccgg tttcttctat tccatcctat acattttggg
     1381 atagtatcta cggaaatctg tttgaatttg acacacttat caagcattta gaaaaaagag
     1441 gtcttctaca tgatcagctt gcagttggcg gggtttcgat ggggggaatg acaacatgcg
     1501 ccttgttggc taaacatcct catatagtag cgggcgtgtg tttgatgggt tcccctgcac
     1561 ctttggaata tggaaaagaa atcgtaaggc gcgcatcgga atataattat gtcgtaccaa
     1621 aagactattt tgatttgatt tcatgggtta agagctatga tttgtcattg cagccggaaa
     1681 agttagctgg acgtcctctg ttcttttggc atggacaagc tgacgaaaaa atcccttata
     1741 tacaaacgga acgatttgta gaaaaaaatc ggcataagtc ttacggaaaa gaaattgttt
     1801 ttcgttcctc aaaaacacag cgacatatgg tacaaatacc actaatggaa gaagcttcca
     1861 cttttttagc aaaaaatttg ataaaaaagt ataaataatt gaaacggaaa atcactcatg
     1921 acgatagagg attttccgtt ttttattttg ggctataata aactctgtta ggaaaatttg
     1981 gtataattga tagtaagaat gacaacatgt tagaaaggaa gagagcatgc ccactttagc
     2041 agatgttgca aaacgtgcca atgtttcaaa aatgacggtc tctcgagtca tcaatcatcc
     2101 ggaacaggtg actgacgaat tgaaagagtt agttttctca gcaatggctg aactggatta
     2161 ccgtccaaat attgctgcaa aagcacttgt cacgaatcgg tcgcagatca tcaaattatt
     2221 tatactggaa gaaatcgaca caactgagcc ctattacatg aatttgctga tgggaatcgc
     2281 taaacggatc ggtaaagcgc attattctct ccaattagtt acaaatgatg ccttcgacgt
     2341 cggttcttgt gatggataca tcatcacagg tgtcagaaaa aaagacttcg attggatcga
     2401 ccgtttggaa aaaccagttg tcttgtttgg ggaaaattct gaaggatatg attatgtaga
     2461 cagcgataat gaatatggta cagcaaaagc aacgcaatat gccttagaaa gagattatca
     2521 aacgattatt tatatcggta tcgaagtgga cgagcctttt gaaatttcaa gggaaactgg
     2581 ttatttatct gtgatgaagg aagttgatct tcctagtaaa atcttgcggt ttccaaatca
     2641 ttcgacagaa gtagaaagat atatgacaga aaactgggca gattttacag ataaaacttg
     2701 ttttgtatgt agttcagatc ggctagcact aggagcagta agagggatta taaatgctgg
     2761 aggacacttg cccgaagaat ttggtgtgat tggatttgat ggggtatttt tagaccaaat
     2821 cagttcacct aaattgacaa cgatcaagca agatattata cgtatgggtg aagtatgtgg
     2881 agaaatgttg ttaaaaaaaa tagaagaaaa aggggcgagt caaggttatc gtcgtttttt
     2941 tcctgaacta gttatcagag agacaacgaa ttaagtctta ttactatata tatatttatg
     3001 aaattcatcg ctattttctt aaaataatca gcgcattgct actgaaaaca atgaatctgt
     3061 gctattattg agaaaagttc catttttgag aaggatggtt tgaatgaaag aaatcagacg
     3121 aaaacatttc cgttttcctg cgtacgatga tgagttaggc gtaaaattaa ccaacgacaa
     3181 gaagcgagta ttatttgacg gacaagaaga tcttttgact gaacagaatc agtccccgtt
     3241 tgaacagatg aaagaatttc atttcacgaa cacgaacacc gagaaaatcc gtcgcaagcg
     3301 tcgtgcaaca aatggattga agtcagctcc gcgtaaggaa aatttggaaa agcataaagg
     3361 aaaattaccg gattataccg gccattacca atcagaaatc acatcgacag gacgaaaaaa
     3421 actttttggt gattcctctc gttctgtcag acaaagtgaa acaaggacag agtccaagca
     3481 tactacacga aacgcatctg ttgacacgaa ggtgcgggag cgttcttatt ttgttcctaa
     3541 atatgtaccc gcatcgatta tcccagaccc tagagaaagc aaaatttctg aggatcattt
     3601 aatcgaatcg atgaaaaaaa cggatgactc ttatctgttg ttcgatacag aaccgacgcc
     3661 gtatcaagaa aaaagaaatg gtgagccgtc tgtacgaaca ttcaatcgaa caaaaacgtt
     3721 agaggaaaca aagcagtcag aagaaaaaaa atcgaaaaaa agccatggta tcttagaacg
     3781 ctcattacaa ggattgatcg atgatcaagg aaactctttg ggagaaaata gctattttaa
     3841 ataagtgata tacaaattta tattcggcta cagttggaaa ggaaacgctg cggcgtttcc
     3901 ttattttata ctctatccga aagtttatat cgtatcctca aatttttttg agtttaagcg
     3961 aattttttct cccaataagt aagaaaataa tggcaaaata aaaaaacaaa ctattttcgc
     4021 agatcgtttg caaaaatagt ttattttttt ataaagaaga ttttactgaa taatatcatt
     4081 ttagtttaca taatgatatt tctgtaaatt aaataaagta gtgaaaaata agaatcagtg
     4141 ctctaactgt tcaagaggat caagtggttc aaatgtttct gtagtctgtt ttgcttccaa
     4201 ttggggcaaa acagatccaa tttccagata cttcacttta ttcaatgtat aagatagaat
     4261 agaacagcta agtaatgtat acagaaaatg tgtgagatcc aaataaagca aggagacaac
     4321 taaaatacca aaagtaatca agaaaagact tttgccaatc ttaatatgaa aatatttttc
     4381 aatggcttga taaatgatat ctgttccgcc tgtgcttccg ccgaatcgaa agacgagacc
     4441 gcaaccaatg ccagaaagaa tacctgtcat caaactattg atcagtagac tatctacagc
     4501 aaaatgtata tgaaggctct cccataaatg taaaaagaaa actagcgcaa atgttccgac
     4561 gatcgtccgg agaaaagcgt gttttccaaa aagaaacaat gagataagca ataaaggtaa
     4621 attaaaaagc agtgaagtga cagaaggagc gaatccaaaa agattatgca aaagcaaagc
     4681 aataccagta accccaccat ctgccagctt agatggaata ttgattcctg tcacagctaa
     4741 tccgtagatt cctgcgccta aaatgattcc gcacaattct gtaaataaat ttaatttttt
     4801 catttctagc ctcttttctt ttgaaaattt tcagcaactt ctttattata ctgacttata
     4861 ctcttacttc aagaggaaaa tgaaaaaaaa ttatttttgg ctgtttcttt ttatttatca
     4921 aataaggagt ggaaaaatgc gagcagcaga cttattgaca attcttacaa aatcacccaa
     4981 aaaaacagag tatcaaggag tttttttggc tcaagaacaa aaactggtgc ctgtgacaat
     5041 ggtccagata aataaagcaa atcaatttat ctttttattt gaacacggca aagcaccact
     5101 tgctatgaaa gacatctttc tttttttgat gaagaaccgt gagaaagctg tttattatca
     5161 gtcaaaagaa gaactcattc ctctttatgg agtgaaagag atagaaaata aagtggtgat
     5221 ataagtaaaa ataagaaaac aagacgttta tgatgtcaaa acaaccattt tttacatttt
     5281 tggcaaaaaa gtgtcatgat acagtataat attcgttgaa caggccaata aaggtgttct
     5341 cccccacgag atttctactt tattggctgt ttctttttat taaaataaaa gttgtgtgtg
     5401 taaaaaagat atagctgatt ccaagtgaca atttcgtata gatttttatg gtattcgtag
     5461 tgaaaaaacg agaaccaaaa agttgatccg actttgttgc ttggattctt tttttgtcag
     5521 catatttaga ggtatttttt tctttttttt gttcgtgctg taaggttaag gcaagacaag
     5581 ttagttggga aaaaggaaag aaatgtttat acttaaagaa taacagaaag gaaggtcgca
     5641 tgaataattt tatacaaaca ttaagtgaaa gaaaaggcga gttgctggaa gctgcatttc
     5701 aacatctgtc catttctctc atttctttgc tgattgcagc actgattgct attcctttag
     5761 cgatttgggc agccaatcat aaaaaaatgg cagaagtctt attgcagatc acgggtgtgc
     5821 tccaaacgat tccttcactt gccttattag gtttacttat cccatttgta gggatcggaa
     5881 ctgttccagc attgattgca cttgttattt acgctttgct tccgattttc caaaacacgt
     5941 atattggtct agctgaaatt gacccgtcta ttgaagaagc agcggtagca tttggtatgt
     6001 ccagaatgag acgcttgctg aaagtagagc ttcccatcgc attacctgtc attatctcag
     6061 gtatccgaac tgccttagtt ttaatcatcg gtacggctac tttggcagca ttgatcggag
     6121 caggtggatt agggacattt attttgttag gtattgaccg aaatacacct gttttgacat
     6181 tgattggtgc gatcagttct gccttgcttg caattatatt cagcggactg attcgctggt
     6241 tgcagcataa gaaacctcga tattccatca ttactttagc agcagtggtg tgtttatttg
     6301 gcggcgtttc tttatatcag tctgccttgt ttaaaaatga aaccatcacg attgctggaa
     6361 aattaggagc ggaacctgaa atcctgatcc aaatgtataa agaattgatt gaagacaaca
     6421 caaaaacaga agttgaatta aaaccgaatt ttggcaagac gagttttttg ttcaatgcac
     6481 tggatcaagg tcaaatcgat atctatcctg agttcacagg tactgtccta gaaagcttgg
     6541 tgaaggtacc tgaagcaatg aaaagtgctg atttgacaaa agaaaaaaca tatgacgaag
     6601 cagaagaatt attgaataag caattcgata tgacattatt aaaaccaatg gcttaccaaa
     6661 atacgtatgc cttggcagtc aagagatctt ttgcgaacga acatcaactt aaaaagattt
     6721 ccgatttggc agctatctct gatcagatca aagcgggatt cacactggaa tttattgatc
     6781 gttcagatgg atataaagga atccaagaag catatggctt gaatttttca agtgtacaaa
     6841 gcatggagcc aagtttgcgt taccaagcaa tcaataatgg agatgtcaat attgtggatg
     6901 cctattccac agatagccag ctcaaggagt acgatctagt gactctagaa gatgatcgag
     6961 ggttattccc agcttatcaa ggcgcaccgc tgatgaaaaa agattttgct aaagaacatc
     7021 ctgaaatcgt taaagcactg aataaattaa gcggaaaaat aacagaggat caaatgattg
     7081 atatgaatta ccaagtcaat gtcgaaaaga aaaagccgac agaagtagca cgaatcttcc
     7141 tgaaaaatga aggattagta aaggaggaag atcagtgact aaattaatcg agttcaaaca
     7201 tgtgcaaaaa aagtatgatg gaaagtatgt catcgatgac ctaaatctgg caatcaaaaa
     7261 aggagaaatc tttgttttgg ttggtccttc cggtagtgga aaaacaacta ctttgaaaat
     7321 gatcaatgga ttatctaaac catcagcagg agacatctac ttcaaaggaa aatcgttaaa
     7381 tgaatataat ctgcagaaaa tgcggtggaa tatgggatat gtgctgcagc aaatcgcttt
     7441 gttcccgacc atgacagtca agcaaaatat tgaagtcatc cctgaaatgt taggttggga
     7501 aaagcagaaa agagcagacc gtgtagatga acttcttcaa aaagttggct tatctcctga
     7561 tatttatcga gatcgtatgc ctagagagtt gtctggagga gaacagcaac ggatcgggat
     7621 catccgagct attgctgcaa gcccagatgt gattttgatg gacgagccat ttagcgcatt
     7681 agatccgatt tcaagaaact cattacaaga attggttttg tccttacacg aagaattggg
     7741 cacgaccatc gttttcgtta cgcacaatat ggaagaagca atcaagctag gtgatcgtat
     7801 tgcatttatg aaggatggag aaattatcca atgtgacaca ccagagcagt tattgatgaa
     7861 tcctaaaaac gactacgttc ggcatttctt tgatgaaccg aaacagacga aagagtggcg
     7921 agtagaagat ttagtcgtca atggatattt cttaaatgaa ataccagaaa atgctcgtca
     7981 acaagtttgc tttgatacgc ctatgaaaga agtatattcg cttctttcgg tgtatccaag
     8041 cattgtgata gtagaaaagc aaagaagtat tgggtcgctg acaagtaaag aaatctttgc
     8101 ttttttaagt cgagaggagg aaggaaatga aaacatatga tgcaatcatc atcggttcag
     8161 gtgtgagcgg cttaagtgct gcttatggat tgaaagaagc aggtaaaaca gtactagtgg
     8221 tcgaagaaga tctatggggc gggacttgtc ctaaccgtgg atgtgatcct aaaaaagtct
     8281 tgttaagtgc agtagaggca cgtaatcggg taaaacaatt gagtggaaaa ggttttaacg
     8341 agatcccaac tgccaactgg gaagaacttc aaaaattcaa acgaacattt acggatccag
     8401 tcccagaaag ccgaaaaaaa caattagcag aagctgaaat cgatcatctt tcaggaaccg
     8461 ctcgtttttt ggatgattca tctattgaag tcaacgaaga agtcttccat gcggattact
     8521 tagttttggc aaccgggcaa agacctacga tcttaccagt ggagggaaag gaatacttga
     8581 aaactagtgc agacttttta tcattgcctg tactgcctaa agaaatcatt tttatcggtg
     8641 gtggttatat tgcttttgag ctagctacga ttgccaatgc tgcagggagc aaagtaacca
     8701 ttgtccatca taatcaacgg ccattaaaag aatttgaggc gtctttggta gaggaagccg
     8761 tccatcaaat ggaagcatct ggcattcagt ttgcttttgg tgttgaaacc caaaagatca
     8821 tttcagaagg tactcgctat cgtttagtcg gaaaagagac ggaattagta gcagatatga
     8881 ttttttgtgc gactgggaga cagccgaata cagaatcttt agcacttgag caagcgaata
     8941 tcgtctttga taaacacgga attgcagtca atgattatct gcaaacgagc aatccaaaaa
     9001 tttttgcgtg tggagatatt gtttcaagga aaaccccaaa attgacacca gtcgccactt
     9061 ttgaaggaaa ttatgtagct aagcggataa cggatgcaac aagcgaacct atcaaatatc
     9121 cgattatacc tacgatcgtc tacgccagtc ctaaacttgc tgaagtagga gttacaaaaa
     9181 gtcacgcctc ttcgtcagat caagtggtag agatggatct taccagttgg ttcacctatc
     9241 atcgtgtcaa tgaaccagtt gctaaggctg aattgacctt tgaccagcaa aattatttga
     9301 ttggtgctgc agtgattagc gagcaagcag acgaattgat cgatgatttg acactcgtca
     9361 tcaatcaaaa attgactaaa aaagagttgg atagctatat catggggtat ccgacattgg
     9421 caagtgatct ctcctattta ttgaaataat cagcatgata actaaagcgc ttgttgcttt
     9481 ttccttcttg tgctacactt taaaaaatga atacctgttt ctggggatgt cgtagacgac
     9541 atgagagtaa gttgtgaact tagacccatt gaacctgtca gttaatactg gtgaagggag
     9601 aaacatagca gacgcttgaa gcgggttact atgtcgtgcc catttcaagc gttttttgtt
     9661 attcatatta gaagaaagga ggtaacaaaa tgaagaaaaa tctttatcca gcagtcagta
     9721 tggcattcat tttaattatt tggcagattg ttgtcatagt ttggaaaata cctgccttta
     9781 ttttacccgg acctgctgct gtattttctg cattagcggc agatgcacaa gtattacttt
     9841 cccattctgt cacgacatta aatgaagcag tgcttggttt ggtaatagct agcgttcttt
     9901 cttttattac tgccttggca atggattatt ggaagttttt agaaatgtct ttttatccgt
     9961 tactagtgat ttcacaaatg ttgccaatca tggtgttagg gccattactt accctatggt
    10021 ttggtttcgg tatgcttcca aaagtgatcc ttgttgtctt gataagctat tttccgatcg
    10081 tagtttcttt ttcggataca ttgaggaaag tatcaaaaga gcaaatcatc tttttgaaaa
    10141 cgatgggggc agatacaggg aagatttatc gaatatataa aataccagcg ggtttatccg
    10201 gcttcttttc cggtttaaaa gtggctgcta cttattgtgt cagcggagca gtcgttggag
    10261 aatggctaag cgctcaagca ggcttagggt attacatgat acgcgtaaaa aacagctacc
    10321 agatcgataa agtttttgct gcgatcattt gtgtcattct attgagttta ttgctgaatg
    10381 gcgcttgttc attattgaaa aaagggtatt atcgtatgct ttatattttt taagagaagg
    10441 ggatcaaatg aaaaaattat ggcttttatt accgctactg ttgcttttat ccgcttgtgg
    10501 cactgcaaaa gaaacaagta gcaaacaaga aataaaggat ttgaaaaaag tgacacttgt
    10561 tttggattat gtaccgaata ctaatcatac tggcatctac ctagcaaaag aaaaaggcta
    10621 ttataaagag gctggtttaa atgtccaaat catcgaacca ggagataatt cgacaagtat
    10681 tggtctagta ggtgcggaca aagcacaatt tggtgtaagt tatcaagaag atgtcactta
    10741 tgctcacgca gatggacaga atataccagt caaagcaatt gctacagtga tcaaacataa
    10801 tacttctgga ttcgccaccc tatcagacag taacatccat tcaccaaaag attttgaagg
    10861 aaaaacatat gcaggttggc aaagtccaag tgaagaagct gtcttaaaag ctgtgatgga
    10921 aaaagacggc ggggactttt caaaactgac aatggtagga agcaatggag aagggccaga
    10981 aagcttagga aaatcctcag atatccaatg gtactttgaa ggttgggata tgatcaaagc
    11041 aaaagaagcg ggtattgaac taaactatat cccattgaaa gaattagatg aacggttaga
    11101 ttactatact ccggtaatta ttacgaatga tcaactgatc aaaagtgatc cagaattggt
    11161 acagtctttt atggatgcca cgaaaaaagg ctatcaggaa gctattaagg atccaaatga
    11221 cagtgctaaa ctgttgcaaa aatatgcaaa agaaaatgat cggacgtttt tagaagaatc
    11281 acaagcattc ttgtcaaaaa attatacgga tgatcctgag aattggggat tgatggaaga
    11341 aaaagtttgg cgcaattata cagcttttat gcaggaaaac ggattgatca agcaagatgt
    11401 accttcgcaa gaactattca ctaatcagtt tataaaatag gagtgataga tatgtcaatc
    11461 caaatcagcc acttgaatgt agtcattgaa aacctgaaaa tattagaaga catccatttc
    11521 actatcccta aagatacctt tacatcgatt gtcgcgccaa gcggagccgg taagtcaaca
    11581 ttgctgaaaa ctttaacagg agtccagcct atgacttctg gaacgatcaa agtagacgat
    11641 caaaaagtaa ctggtctcca tacagcattt agttatatgc cgcaagaaga tatgttactt
    11701 ccttggctga gcgtctatca aaacgttacg ttatatcaaa aaatcaatca tctaacaatc
    11761 aatgaagaac aagtaaggga ttatctggat atctttgggt taaacggcta tgaacatttt
    11821 ttgccggaac aattatctgg cgggatgaag cagcgaacgg ccttgttacg aacaatcatg
    11881 aatccttctt cttacttgct tcttgatgaa ccatttggag cgttagatgc tatgaccaga
    11941 gggcagatgc aagactggat gttgaagctg cctaaaaaag caaagcggac tactttactt
    12001 gtgacgcatg atatcgaaga agcaatttat ttatcagaca ggattcttgt gctttccgcc
    12061 cgtccggcac atgtgattgc tgagattcaa gtgcctgaaa aacgacggtc acgtgaatgg
    12121 ctactgcagc aatcagagtt gaagcaaacg atttatcagt tattggcagg tgaattagat
    12181 gttaagtgat gctcattgtc atttagatgg gagtcagagt ttagcactcc ttcagcagga
    12241 acacacgatt ttgacgatca tcaattgtga ttcgccagaa gaatggaagg aaaacagaca
    12301 gcttgcagca agtaagactc aagccttaag ttacggtatc catccttgga aagcagatag
    12361 ctatacgttt gaacaagttg agcctttttt gaaaaaagca aggatcatcg gtgaaatagg
    12421 gttagataat atttggacga atgtaccgat gactacacaa aaaaaagtat ttgagcgaca
    12481 gcttgctttt gcagccataa atgagaaacc tgttgtactg cacacaaaag gatgcgaaaa
    12541 agagatctta aattatatcc aagcttaccc taatcactat ttgatccatt ggtattcttc
    12601 tttggactat caacaagact atattgattt aggctgttat ttcagcattg gtcttgattt
    12661 gaaaaagaat ccagcagtct ggcaactagc taaagcagtc ccaatcgacc acttacttat
    12721 tgaaacggat ggactacatg cagcagagtg ggctttaggg gggatttttt cagaaaaaga
    12781 ttatgtctca ctgcttgaag aacagttaaa gacaatcgct gagatcaaag agctatcagt
    12841 tgaagaagtt aaaaaaaata cttatcaaaa cttggaacgt ttcattagat taggtaaata
    12901 aaaaagagat gtgacacaac tagtgtcgca cctctttttg gctttctttg tataaaagta
    12961 aactgtttga ttaataaatg aatcttagta ccaaccgttt gcttcccaga atgctttcgc
    13021 cgcttcccaa gaaccataac gtgaagtaac atattgttct gctactcttt cttggtttgc
    13081 agcagagtag tcaccattta agtaagaaga atctaattgg taacgtccga tgtaacgtcc
    13141 gttcgttgct gtgtaagaac cgcttgattc tttttgtgcg atccattctt ttgcagagct
    13201 tgtgcttgct ggagtagcag cagtttctgt tacagcagga gcaggttgtg tttcagcaac
    13261 aggcgctgct tgtttttccg tttgaaccgt ttcttgtaca acaggttgtt cagcttggac
    13321 tggtgcttct tgaacggctg cttgaggttc agcagctgct tgtgcagagc cttctgttgg
    13381 gattgttaat tgttgtcctg agta
//
LOCUS       DAIGSZ010000070        13159 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.071, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000070 DAIGSZ010000000
VERSION     DAIGSZ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13159
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.071"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            126..1865
                     /gene="yfcC"
                     /locus_tag="NOB31_002320"
     CDS             126..1865
                     /gene="yfcC"
                     /locus_tag="NOB31_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCI0974503.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2022..3206
                     /gene="iadA"
                     /locus_tag="NOB31_002321"
     CDS             2022..3206
                     /gene="iadA"
                     /locus_tag="NOB31_002321"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HCI0974504.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3317..3520
                     /locus_tag="NOB31_002322"
     CDS             3317..3520
                     /locus_tag="NOB31_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCI0974505.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3621..4283)
                     /locus_tag="NOB31_002323"
     CDS             complement(3621..4283)
                     /locus_tag="NOB31_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974506.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4296..5798)
                     /locus_tag="NOB31_002324"
     CDS             complement(4296..5798)
                     /locus_tag="NOB31_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0974507.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6346..8025
                     /locus_tag="NOB31_002325"
     CDS             6346..8025
                     /locus_tag="NOB31_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCI0974508.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8152..8631
                     /locus_tag="NOB31_002326"
     CDS             8152..8631
                     /locus_tag="NOB31_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HCI0974509.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8850..9530
                     /locus_tag="NOB31_002327"
     CDS             8850..9530
                     /locus_tag="NOB31_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCI0974510.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9538..10869
                     /locus_tag="NOB31_002328"
     CDS             9538..10869
                     /locus_tag="NOB31_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0974511.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10884..11846
                     /locus_tag="NOB31_002329"
     CDS             10884..11846
                     /locus_tag="NOB31_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HCI0974512.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            11957..12295
                     /locus_tag="NOB31_002330"
     CDS             11957..12295
                     /locus_tag="NOB31_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HCI0974513.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12374..13081
                     /locus_tag="NOB31_002331"
     CDS             12374..13081
                     /locus_tag="NOB31_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HCI0974514.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
BASE COUNT         4185 a         2321 c         2885 g         3768 t
ORIGIN      
        1 aaaatagaaa aaagtgattt tctaataaat tattcatgtg gaaatgtcat ttttactgta
       61 taattcattt gattatccat tttttattca tcaaaattac tgaaaaaaga aaggaagaaa
      121 taaatttgaa gaaaacaaat tcttcaggaa aaccgaaacg cgacttcact aaattatcga
      181 caccccatac gtatgtcatt atttttggtg tagtcatctt tgcatggata ctgacttttg
      241 tcgttccagc aggaaagttc agcacgcaag atattgaata caaagatgca aatggcgaaa
      301 caagtactcg tactgtttta cgtcaagatt ccttccgtta tgcttacgag ctggataagt
      361 cgtatgtgtt tgatcaatta gaagaactgc aagatcatcc agcagaacgt gaaaaactgg
      421 atgttccgga aaaaggattg gaaaaagtca ttgctgacgg agaaaaaaat cttacgcagg
      481 aaaaactaga tgaaatctcc ttgacagatg atgtgcttta cgatcagtac ggcgaaaata
      541 tctatgatac ttctaaaaaa ttgcataaaa cagccaaaat atggggaaca gatgattttg
      601 gcggctttgg tttcttaaat tttgtttttg aaggactagt atctggagat aagtatggat
      661 ctgctgtagg gatcgctgca ttgatccttg ttgttggagg tgcttttggt attattatgc
      721 gtaccggagc gatcgacgca ggtatctatg cgtttatcag taaaactaag ggactggagc
      781 gtttagcttt accgctatta ttctttgctt tttcattcgg tggcgctaca ttcgggatgg
      841 cagaagaggt aattccattc tcaatggtga tggttccatt tgtcattgcg ttaggatatg
      901 actcgatcgt agcagtaacc gtgacttatg tcgcatctca agtcggaaat gcgacctctt
      961 ggatgagccc gtttagcgta gcggtggctc aagggattgc tggaatcccc gtgttgtctg
     1021 gtgcgacatt ccgattgatt atgtgggtag ttgttactgc attagccgct ggttatatga
     1081 tgatatatgc agaaaaaatc cgtaaaaaac cagaaagttc gttgacttac aaatcagatg
     1141 attatttccg ttctcatatc aaaaagacat ctgatgaaaa taaaaaattc atgcttgggc
     1201 ataaattgat cttattagag atgttagttg tccttgtctg gatcgtttgg ggcgtgactc
     1261 aaaaaggcta ttacattcca gaaatcgctt ctcaattctt tgtgatggga ttagttgctg
     1321 gaatcattgc tgttcttttc aaattagatg gaatgaaagt caatgacatc gcttcttctt
     1381 tccaatctgg tgcagctgat ttagctggta cagcaatcgt agtaggtatg gccaaaggga
     1441 ttcttcttgt cttgggagga tctgatgcat ctgttccttc agctttgaat acgattttgc
     1501 atgggatcgg gacggcgttg accggtgttc cagctgtcat tggtgcttgg gcgatgtaca
     1561 tcttccaaag tttgttcaac ttggttgtta catcaaattc aggacaagca gctttgacta
     1621 tgccaatcat ggctccactg gcagatttag taggtgtatc cagacaagta gcagttcttg
     1681 cttatcagct tggttcaggt tttatggacg cttttacacc cgtatcagcc agcttgattg
     1741 gtgtgctagg tgttgcacgg atcgaatggg caaaatgggc aagattccaa atcaagatgc
     1801 aaggattcct gtttgtttta ggaactattt tcatcatgat tgccattgca ataggtctgc
     1861 agtagtactg gagacctgta aataaaaaag taatccaaac agtagataag gactccaaga
     1921 accgtcattt tacggtaaaa tcaaaggagt aaagatccta tcgtttggat tattttttaa
     1981 gatcctatca tcagttatac ttaaagaaag aggaaaaatg tatgaaaatc attcgacaaa
     2041 ttgaagtgtt tgcaccagat tacttaggaa aaatggatgt actgattgcc ggtgggaaga
     2101 ttttggctgt agaagaacag ctagaaggcg gctacgaagg agtggaagta gaagaacttt
     2161 caggtgaggg aaaagtacta accccgggtt tcattgactg tcatttccat attttaggtg
     2221 gaggaggaga aggcggttat caaaatcgaa cgccagaagt cacattgagc caattgacta
     2281 cagctggtgt aacgacagtt gtcggttgtt tgggaacaga cggagaaggt agagatatga
     2341 ctgcgttgat cagcaaagcg aaaggtctgg aagcagaagg aatctccact tatgtatacg
     2401 aaggttcgta ccgattgccg gtaaaaacag taacagattc tatcatcaaa gactttttga
     2461 caattgataa aattatcgga atcggagaaa tcgcagtatc cgatcaccgt tcttctcagc
     2521 caagttttga agagttcgct cgtgcagtag cagatgctcg tgtaggaggc atgttatccg
     2581 gaaaagctgg gatcatcaat gtccacttag gcggaggaaa aagaaagcta gagctattga
     2641 cacgaatcgt agaagaaaca gaaattccga tcacacaatt tttgcctact catgcaaatc
     2701 gcacaccaga attatttgaa gcttgcgtgg catttgccaa acgtggtggc acgattgact
     2761 tcactgctag cgaagatcct gatttttggg agaagacaga tggtgaagtt cgcttcagca
     2821 aagcactgaa acgattgatc gaggaagatg tttctttaga taatttcacg atgacctcag
     2881 atggacaagg aagcttgcct tattttgatg aaaacaatca tttcctaggg ttaggagtag
     2941 gaagtgccaa ggcattgcta gtagggatca aagaagctgt gcaaaaagaa agtatccctt
     3001 tggaaatcgc cttacgagct ataaccagta atccagcacg tatattgaaa ttggataaaa
     3061 aaggaaaaat cgaaattggt gctgatgcag atctgtgtat cttggataaa gaaacgcttg
     3121 atattgatac agttatcgct aaaggagaaa taatggtcca agaaaaagaa gtcaaagtat
     3181 gggggacttt cgaaaaaagt ttttaatcaa cagctctaac tatctttttt agaaaacgag
     3241 cgttctgttt gtctgtatct gttgttgatg ttaccctgaa ggtagatcaa taaacaaact
     3301 aagaggagga agcacaatgg cagatttaaa aggacgttct aaagatatga aagataaagt
     3361 agtcggtgaa ggaaaagaag catacggcaa agcaacagac gacaagagca aagaaacaga
     3421 agggaaagca caatcactag gtgctgacat caaagaaaaa gctcgaaatt taggcgacga
     3481 agtcaaagac aagttttctc gaaaagacga aaaaaaataa aaaccactta ttactaattg
     3541 aatcaagcaa ataaaaaatc cgaaccatat ctgcgagaca gatatggttc ggatttttta
     3601 tttgatcatt atcctgtttt ttaaacttcg attttttgaa attttttatt ttttagttca
     3661 aagacttcat cacagctttt tgctacttca atctcatgag tcacgatgat aatacagcga
     3721 ttttgttcat gggcgatttc ttggaaaagt ttgacgatat cttgtgaagt tgtttcatct
     3781 agatttccag taggctcatc cgctacgatt agttgatgtt cacagcagat agcacgaacg
     3841 atagcgactc gctgctgctg acctcccgaa agtttggtca cctgtttttt tgctaatatt
     3901 tcatcaattc ctacacgagc cagtcgatct aaagcaactt gtcgataatt ctcttgcttg
     3961 gtcttagtga tttccattgc tgctatgacg ttgtctagag ccgataaata aggaagcaag
     4021 ttgtaagctt ggaaaataat cgagacatca tttttacgat aacttcttaa cccgattttg
     4081 ttcagtgaac gatcttgata gtataccttt ccttcttttg gtgcatctag tccagaaata
     4141 agcgaaagaa aagtcgtttt tccagaacca cttgctccta aaatagcgta catttttcca
     4201 gcttcgaaat tcagttctac atctttataa agcgcatctt gcggatcttg ataccaaaat
     4261 cccaattgtt ctgtccgtaa catcaaattc ctcctttagt ttaataggat ttttcttggg
     4321 tttaatctta atatccctat agaagctaaa aagacagaaa acagactgat tccaaatgct
     4381 actccggcta atagtcccaa ttgtgcaggt ttgacattga tttccaattc gctgacttga
     4441 tcagaaacag caaatggatt attcgtggtt ccttgttgac catcgcgttg accgccttgt
     4501 tcttgtctgt tacctggcat ttgtccaccg ccaggagctt gctggttttg tgtcgtggtt
     4561 tctgtctgtt ggtcaagtag ctgctgtccc acggcattcg cgacgacgtt tccgctaagc
     4621 gaagcaactc ctaatgcaag aatcatacaa atagccactt cggtaaacaa ttggagaatg
     4681 attttacttc tggattctcc taaagatagc aagacgccta actcatgccg acgctcccga
     4741 atggtaatca taatgatcag agtaagtatg ataataccgg ctacagccac tagtaaaaca
     4801 acatttttag aaaaacttgc cacgttgttt aaaggttcca acattgactg atacatggaa
     4861 tcatttgatt gtaagctaaa tgtatctgtg tcgatcagct tctcagcttc tttgagaaac
     4921 tcatccattt tatctggatc agatagagtg taaatagcag aatctatcgt gttatcgtca
     4981 gatgtcccat ttagttcatt tgcaaaagtg taagaagtgt aaagtgtatt cgacggattc
     5041 atgaagttga atttcatacc catactgccg cttgtttcgc tggattcata aattcctttg
     5101 atcgtcattt cataagtggt atcttcatct tcagtactcg tgattgtgaa agtatctccg
     5161 actgccaggt catttgtttc tgctagagta gaatcaatga ctacattgtt tgtgcctttg
     5221 tcgctgtcat ctattccttc accatccgtg atttttgctg ttccatcaga aaaattacta
     5281 ttttgtgcag ttgctgacac accactgatt tgaaagtctg cttgagtcat ttgcggattc
     5341 ccgcccattc ctccagcagg ttcaccgcct gcatcagtag tttctgaact gtcttcactt
     5401 gaatcagaac tagtgatggc agttattcca tcttttgcca tagctgaggc ggaactttca
     5461 aaggaataac tctttacatt atctaattca gctatttttt ccgcgtccgt taaggaaact
     5521 ggtgtaagag aaaaactgcc tggatctgga cgttcttcag tggtagaacc gcttgaagaa
     5581 gtttgttcct gttttttaaa tgaagcttct cgattggcac ttaaagtcac tgttgctcca
     5641 acttcttttt gtgcttgatt cgctgcttct tctgcagcgc ttcgaatcgt gaggccagct
     5701 agcacaaaaa taagaatggc tgtgaacacg gcaaacaata acaatgaacg tccccatttt
     5761 acttttgtac ttttccatgc acgtttcata aaattcatat tttgcatccc tcctagtaga
     5821 tgcatttgat aatagacaac ctatcttaaa gctagcttaa atcttatgct gtttgcacac
     5881 catcaacatg aggttctgta tatataaaaa gtcactatag ttattgcaaa aaatgtggta
     5941 aaatgaaaaa agtatgtttc aaaccgacga agaagaaatg aaagaggaat agcaaaagaa
     6001 atcctagatg ctacagaggg atttttacgt gcatagttgt tctaacaatt gctgatacta
     6061 gcgatttagt ttatttgttg tataataatg gggaacagct gaatacttat ataagtattc
     6121 tggctatagc gtttcgcaaa agatccattt tgttaatgaa gtatatccaa aataaaatgc
     6181 ccatccaact gtcagaacgc ggatgtgctg gtaattttcc tgctgattct ccataagttg
     6241 agaaatagtg attttgcata tgcttcattg gaatggctca tatatttaga taaagaagaa
     6301 aatcgacatc tttaaacttg gatgtcataa gaagaggtga agtttgtgag taccattaaa
     6361 attatcccat taggcggcgt tcgtgaaaat ggaaaaaaca tgtatgtcgc agaagtgggc
     6421 gaggatattt ttattttaga ttgtgggcta aaatatcctg aaaatgagtt gttggggatc
     6481 gacgtcgtaa tccctgattt tacgtattta gaagaaaaca ttgatcgtgt agctggtgtc
     6541 tttttaacac atggacatgc agatgcgatc ggggcacttc cttacttgtt gtcaaaaatt
     6601 tctgtaccag tattcgggac agagttgacg atcgagttag caaaattgaa tgtcagtcgt
     6661 aatgaagcag ccaaaggatt taaggatttc catgtggtag atgagcatac agaaatagac
     6721 tttggtgaaa cagtagtgag ctttttccgt accactcata cgataccaga ttcagtgggg
     6781 atcaatctga aaacaaaaga aggtagtatc gtttatacgg gagattttaa atttgaccaa
     6841 acggctatcc caatgtatca aacagattat gcacgattgg cggaaatcgg caaagaagga
     6901 gtcttagcct tactaagtga atcggcaaat gcagaaaatc ctcagcctgt agcttctgaa
     6961 gcccaaatag cagatgaagt atttgatacg atcaaatatt gggaagggcg tatcatcgtc
     7021 gcttgtgtag caagtaattt gcaacgagtg caacaagtat tggatgcagc agaaaaagca
     7081 caacgaaaag ttgtcttgac tggtcaagat ttcgaacgaa ttattcgcac agcgatgcgt
     7141 ttagaaaaac ttcaattacc aagtgaagat ctgcttgtta cgttgaaaga catgaaaaac
     7201 tatgatccag aagaactgat cattttagaa actggccgaa tgggtgaacc catcaagtct
     7261 ctgcaaaaaa tggcaaacgg tacacaccgt aatgtcaaga ttgaagaagg agatttggtt
     7321 tatatcacta ctacgccaag catcgcgatg gaaaccatcg tggcgaaaac ggaagatatc
     7381 atttatcgag ctggtggaac agtgaagttg atctctgaga atatgcgcgt ttctggccat
     7441 gccaatccta atgacttgca attaatgatc aatttgatga aaccaacata ttttgtgcca
     7501 gttcaaggag agtatcgtga attagctgct catgcagatt tggctcatgc agtagggatg
     7561 ccatacaaaa atatctatat tactggacgc ggagacgtgc tggaatataa gaacaagcgt
     7621 atgagtgttg caggaactac aagtgcagaa aatgtaatga ttgatggatt aggcataggt
     7681 gatatcggaa acattgtttt acgtgatcga aaaatcttgt cagaagacgg gattttcgta
     7741 gcggttgtca ctatcagtcg gcgagaaaag aaaatcattt caaaacctca aattacttca
     7801 cggggattcg tttacgtaaa agctagccgt gatctgatga aagaaagcag caatatgatt
     7861 gaaacaatcg ttgagaaaca tttagaaagc aatgattttg agtggagcaa attaaagcaa
     7921 gacatccgag atcaattagg ccgttactta tttgaacaaa caaaacgccg cccagtgatc
     7981 ttgccagtca ttatggaagc tactcaacgt cgaaataaaa aataaacaaa aagagtaaga
     8041 tgaacctctc tatagagtgc tcgtcttgct ctttttttgc gaaaaacaaa taatttttga
     8101 atacagcatc cctcgcttta taataaacga tagaataaag ggagtgaatc aatgatgagt
     8161 caaacaaaag tcgaacgtta tttagaagaa caaaagatca gctatcaacc acttgatttt
     8221 agtcatgtgg tagaagaatc tttcacagaa gaactacaaa aaagagggat tgatccagct
     8281 ttgatatgta aaactctcgt agtgaaagga aacaaaactg gggtgatcat cgcattgatt
     8341 cctttgaacg atcacttaga ttacaaaaaa acgagacaag tgacgaaaga tcgtaaagtt
     8401 ggttttcctg gaatggattt tgtattaatg catacaggat atccccacgg agcaaacacc
     8461 cctattggaa taaaactcgc acatcctgat tattgttttt tagcagacag ttctttaaaa
     8521 gaaaaagaag aagtaattgt gtcaagcggt gaaatcggga gaagccttcg gataaaagta
     8581 gccgatttag aaaagatcgt ccatcctatt tacgctgatt taattagtta agggacgaga
     8641 agagaagcta agcagagcag agacctcaaa cttgagatta tatctgcttg gtacttggtg
     8701 catcctgtat tatctgttac aattgctttg tacatactgt actatcaatc caatgaaaat
     8761 atatttagca gctatatttt ttcattgatg tgcaagtgat gaaatcgttt ttaataaaaa
     8821 agatacagag aaaacgcgag gtgtaaaata tgaaaattac gtatcatgga cattcctgtt
     8881 taacaattga aatggaaaat ggccaacgcg tgatgattga cccgtttatt acaggaaatc
     8941 cattgacaga cttaactgca gaagaagtaa agacagattg gttgctgatt actcatggtc
     9001 atagtgacca cataggagat atgattccta ttgcaaaaga aaatcaagcc acaattatca
     9061 gtattgttga gattgctgat tatgcgaaca gcagaggagt agattcattc ggtatgaata
     9121 tcggtggaaa acatgcgttt ccattcggcg tggtaaaatt cgtacatgca cagcatagtt
     9181 caagctatga agtagacggt atcgttcagt atatgggcga gcctagcgga attattattc
     9241 aagcagaagg aaaaacgatt tatcatgcag gggatactgc ttatttcagt gatctaggat
     9301 tgcttgcaga agaattcgat attgatgtcg ctttcttgcc gattggcgat aactatacga
     9361 tggggccaga agatgcagca aaggctgcgc aaacaattcg tgccaagaaa gtagttccaa
     9421 tccattacaa tactttccct gtcattgaac aagatcccga atcttttgta gagttactgg
     9481 aagatagtga aggaaaaata atgagcgtct cggaaacgct ggaagtgtag gcagaaaatg
     9541 gcgacaaaac atgatttgat tttagaatat attgaaagtt tacctgttgg caatcgaatt
     9601 tctgtaagaa gcatcgcaaa agaattgaat gtcagtgaag gaacagcgta ccgtgcaatc
     9661 aaagatgcag aaaatgtcgg actagtttca acaattcaac gagtagggac catccgtatc
     9721 gaacgcaaat taaaaaaaca tattgaacgt ttgacatttg gcgaggtcgt caggatcatt
     9781 gaaggggacg ttttaggcgg ggcggcagga ttagacaagg tcttgaataa attcgtcatc
     9841 ggcgcgatga ctaaacatgc catggaacgc tatattacgc caggatcact aatgatcgtc
     9901 ggcaaccggg cggaagtcca aaaattagca ttggaagatg gcgccgcagt attgatcaca
     9961 ggaggattca atacgactgc tgagattgca aagctagctg atgatcttga aatgccgatc
    10021 ttacgcacct cttatgatac atttacagtc gcaaccatga tcaaccgagc gttaagcgac
    10081 caattgatca aaaaagatat catgcttgtc agtgatatct atatgccagc tgaaaagact
    10141 cattatttgc agcagacaga tacgatttct gattatcagc gtttgtcaga agaaacgcag
    10201 cattcgcgtt ttccagtcgt caaccgccat catcgtttga tggggattgt tacggcaaaa
    10261 gatgttttag ggaaatcgcc aaaccagatc atcgatcggg tgatgacgaa agaaccaatc
    10321 agtgtaaaga aaacaatgag tattgcctct gttagccatc aaatgatctg ggatgggcta
    10381 gaagtcatgc cggtcgtttc cgatgacttg acattggaag gcttgattac ccggcaagat
    10441 gtaatgaaag cgatgcagct tgtccagcga caaccgcaga ttgcagatac gatttcggat
    10501 cagatatctg gaaatatcca tacgattgat actgaccgtg aaggaaatcg tttggaaaac
    10561 cctaagttca aattcgtagt agcaccacaa atggtcaatg gcgttggaac catttctttt
    10621 ggcgtactta gcgaaatcat ttctgatgtc gcacaaaaaa caatggtgat gaaccaaaaa
    10681 cgaaatatct tgattgaaca agtgaaccta cattatttgc ggctgatcca attggaaagc
    10741 gaattagaca ttcgtccacg tgtattggaa atcggcagac gttccgctaa actggatatc
    10801 gaagtgttta ttgaaaacac catcgtttcc aaagcaatcg ttgtttgtca agtaatggaa
    10861 cgttcttaga aagcaggagt gaaatgacag tacagcaaga aatagtagat acaataaaaa
    10921 aatacgataa aatcattatc cacaggcatt tgcgccctga tcctgatgca ttaggatcac
    10981 aagtaggatt agccgaacta ttacgggaaa gtttcccaga aaaagaaata cgtcaagtag
    11041 gtgaaacgat tgaagggctt cgctttttag cagaaatgca agaagttgaa gatgtcttct
    11101 accaaggagc gctagtcatc gtgactgata cagctaattc acccagaatc agtgatcaaa
    11161 gatatcagtt ggcagaaaaa ctgatcaaaa tcgaccatca tcccaatgat gacccttatg
    11221 gagatcttgt gtgggtaaat acaaaagcaa gtagctgtag tgagatgatt gcagaatttg
    11281 ctttgatgtt tcctgaatct ttaaagatga acgttaaggc tgcacggtta ctttatgcag
    11341 gaatcgtcgg agatacaggg cgctttttgt atccctccac gacgtcccgt acattagaga
    11401 ttgcttcgat attgagaaat tatccatttg atgcaagtgc tttgaacaga gagattgaac
    11461 aaatgccgat gaaagtcgct aaactttccg gttatcttta tcaaaatatc caggtggatg
    11521 aaaatggtgc aggaagaata atccttccgc aagaaattct tgataaatat ggaatcgatg
    11581 attcagagac agcttcgatc gtttcacttc ctggagtgat tgacgaagtg ctggcttggg
    11641 ggatttttgt tcagcagcct tcagggtatt accgcgtacg tttacgttct aaggggccga
    11701 tcatcaatga attggctaaa cgccatcatg gaggaggcca tccattagca agtggtgcga
    11761 atgcaaaaga tttagcagaa gtagaggaaa tctataaaga gatccaagat atatgccaat
    11821 cgtataagag cagaaaaaca gaatgatact tcgttcgaaa acgtgccttt tgtagtaaaa
    11881 atcacaaatg tatcttttca agatcttctt tttccgttac aatagtgctc actaaagatt
    11941 ttaaaggaga aagaagatga cattaccaaa ttgcccagaa tgtggctcag agtacacata
    12001 tgaagatcga ggcttgttga tttgcccaga atgcgggaac gaatggaaca aagaagaaca
    12061 agaaactgtc atagaagacg gattagtggt attagatgca aatggaaacc gtctgttaga
    12121 gggcgatagc gtgacagtga ttaaagactt gaaagtaaaa ggtgcgtcag gtgccattaa
    12181 acaaggaaca aaagtcaaga acatccgttt agtagaaggc gatcataata tcgattgcaa
    12241 ggtagaagga tttggaccga tgaaactgaa atcggaattt gtgaaaaaga attaaagaat
    12301 attcaaggtc ttttcacatt cttttcctac tactaatgat aaaataaagt aaacgaaaag
    12361 gagtgaaacg aaaatgtatg gttatggaat gtatggtttt ttagatccga catttctttt
    12421 ggtcattctt ggattagtta tttccggaat tgcgtcagcg tacgtcaata gtactttccg
    12481 aaaatacgat caagtgagaa gcaaaaacaa tgtgactggt acacaagcag cacaatatat
    12541 attacaaagt caacagataa ataatgtcgg tgttcaacaa attgccggag atctcacaga
    12601 taactacaat tcaggtaata agatgttgag tttgtctcaa gcaactgcac agtctacttc
    12661 agttgctgcg ataggtgtag cagctcatga atgcggacat gcggtacaag atgcttcggg
    12721 ttatgtccca ttgaagattc gtgcagcact tgttccagca gctaactttg gttcgatgat
    12781 ttcgttcccc ttgattatgg taggtgtatt gcttagctgg aactctacgt taatcaatat
    12841 cgggattttc gctttttctt tagcattact tttccaattg gtgacattac cagtcgaatt
    12901 taacgcgtct cggcgagcaa tccaaatttt gagtgaaggc ggactactga cggaagaaga
    12961 agtaccgatg gcaagacacg tattatttgc agcagcactg acttatgttg cagcagcgct
    13021 ttcgacattc ctgcagctgt tgcgcttgat cttattgttc ggcggcaacc gaagagatta
    13081 aaataaagaa gttgtgaaat cagcgctttg atctgagcta ataccgagag ttagctgatt
    13141 gaataccatt tatttggaa
//
LOCUS       DAIGSZ010000071        13148 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.072, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000071 DAIGSZ010000000
VERSION     DAIGSZ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13148
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.072"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(78..150)
                     /locus_tag="NOB31_002332"
     tRNA            complement(78..150)
                     /locus_tag="NOB31_002332"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(115..117),aa:Lys,seq:ctt)
     gene            531..1100
                     /locus_tag="NOB31_002333"
     CDS             531..1100
                     /locus_tag="NOB31_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HCI0974515.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1087..1947
                     /locus_tag="NOB31_002334"
     CDS             1087..1947
                     /locus_tag="NOB31_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCI0974516.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2137..2841
                     /locus_tag="NOB31_002335"
     CDS             2137..2841
                     /locus_tag="NOB31_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0974517.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2846..4681
                     /gene="walK"
                     /locus_tag="NOB31_002336"
     CDS             2846..4681
                     /gene="walK"
                     /locus_tag="NOB31_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HCI0974518.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4678..5994
                     /locus_tag="NOB31_002337"
     CDS             4678..5994
                     /locus_tag="NOB31_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974519.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5995..6864
                     /locus_tag="NOB31_002338"
     CDS             5995..6864
                     /locus_tag="NOB31_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HCI0974520.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6919..7728
                     /locus_tag="NOB31_002339"
     CDS             6919..7728
                     /locus_tag="NOB31_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI0974521.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7831..8460)
                     /locus_tag="NOB31_002340"
     CDS             complement(7831..8460)
                     /locus_tag="NOB31_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HCI0974522.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8630..9922
                     /locus_tag="NOB31_002341"
     CDS             8630..9922
                     /locus_tag="NOB31_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0974523.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9998..10660)
                     /locus_tag="NOB31_002342"
     CDS             complement(9998..10660)
                     /locus_tag="NOB31_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCI0974524.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10885..11169
                     /gene="groES"
                     /locus_tag="NOB31_002343"
     CDS             10885..11169
                     /gene="groES"
                     /locus_tag="NOB31_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HCI0974525.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11220..12845
                     /gene="groL"
                     /locus_tag="NOB31_002344"
     CDS             11220..12845
                     /gene="groL"
                     /locus_tag="NOB31_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HCI0974526.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4371 a         2265 c         2833 g         3679 t
ORIGIN      
        1 ataaaaaaag aacagcgtaa atgttttcga aatgctttcg caccaacatt tacctgttcc
       61 gtgggtttgg cacccaatgg gccgtgaggg gctcgaaccc gcgacccgct gattaagagt
      121 cagctgctct accaactgag ctaacggccc gtacaaaaag tacttaataa tagtagcact
      181 aagaatttta aaatgcaaga ctacatttaa agaaaatcag aaaaatcttt acttccttat
      241 aggaaatcat tcatagatta ttcacatttg ctcgctatta tataagcata ccaacaaaca
      301 aagttcttgc aagagaacaa accctaacac ttttttcatt ttttactcct ttcccgccgt
      361 ctccccggcg ggtctcctgt tcttaacgat aaaagacaag aaggcttagc cttcttgttt
      421 tttgttttca tggaatcccg ctaatcaaat cacctagtta aagcaactag attgaatgtt
      481 tatcataagt ctgatatcat gtttatgaaa tgaaaaaagg agcggttatg atggaaaaaa
      541 tgcgtcagca attaatggag tgggggaagg aactagaaac attccgtctg cctcactggg
      601 aagaactccc tgacttagaa ctttatatgg accaagtcag aacgttagtt gatcgttatc
      661 tttcacctgt gatacaagga gaaaagcatc cattgcttac ctcttctatg gtaaacaatt
      721 acgttaaact aggtttgata ccagcaccag ttaaaaaaag atataacaaa gaacacgtag
      781 catttttact tgcaatcact acgttgaaac aagtattgac tattcctgaa atcaaagaag
      841 ggatattgtt ccaaggaaaa acagtaggaa ttcgtgaagc ctataatcta ttttgcgatg
      901 aacaagaagc agctgtgtgg atggtcagcc aattagcaca aggtaaatct catccgcaaa
      961 aattcgacca ggcaacccct gtagaatata ttgctgtaag agcggcaact ttatcgtttg
     1021 caatgaaact tcttgcggaa aaaacgattg ttctagaaac cgaatattta aaagaggaga
     1081 aaacaaatga aaaacaataa aatcgcaatt ttagtagatt caggtacgga tgtgccagaa
     1141 gaattgataa aaaaatacga gatgtatatg atcccattga aaattattta taaagatcag
     1201 gtatatacag ataaaattga cattacctct gaagagatct atcaacgttt gccagaggaa
     1261 atccctggta catctttgcc ggatggtgag tcgatcacag aaatctttga gcaaatcaaa
     1321 aaagacggtt atgaaaaggt acttgcggta acaatttcca gtggattgag cgggacatat
     1381 aatgtggttc gtttaattgc acaacagcaa gaagaattgg aagcatatgt actagatacg
     1441 aaaaatattg gtattggtgc aggtttttct gcgatccaag cagcaaaatg gctggaagaa
     1501 ggagtagaat gggatcaact gatcagtaat ctgaatgagt tagtcgaaag aacaaaagtt
     1561 ttctttaatg ttgcgacatt ggaatatctt caaaaaggtg gacggatcgg tttagttgct
     1621 tctattgtag gaaccgcttt aaagcttaac ccaatcatct catgtaatga agaagggatt
     1681 tattacacag taggaaaagc taggggacgt aaaaaaagtt tggataaaac ggttgcttac
     1741 gtcaaagaaa aaatcggtaa tgcaaaggtc ttcaacttag ctgttgccca tggggatgcg
     1801 aaagaagaag caattgaaat ggaagcgaga cttaaaagag agttcccaca agcaaaccaa
     1861 atctactttg gccagatttc tccggcatta gtagtccaca ctggtccggg attattgggt
     1921 gtcggtgtac aagttttaga aggataaatc aaaaaaagga aacactgagg tgaaaatcag
     1981 tgttttcctt ttttattgaa gttagaacaa aaaataataa agtattttgc actttcattt
     2041 taattttctc ttttgtttta taggcaaaga tgaaacaaaa gcagaaatac ggtataatga
     2101 gaaggtatga caataatata taagaggtgg ctctttatga aaaaagtttt agttgtcgat
     2161 gatgagaagc cgatttcgga tatcgtcaaa ttcaatttag ccaaagaagg ctatgatgtt
     2221 tatactgcat atgatgggga agaagccttg gaaaaagttg ctgaggtaga acctgatttg
     2281 attttacttg atttgatgct acctaaaatg gacggcttag aagttgctcg tgaggtacgc
     2341 aaaacttatg atatgccgat cattatggta acagccaaag attctgaaat tgataaagtc
     2401 ctaggcttag agttaggcgc cgatgattac gtgaccaagc cattttccaa ccgagaatta
     2461 gttgcacgtg tcaaagcaaa tcttcgtcgc ggtgccacgg ctgcgaagga accagaagag
     2521 gcagcacctg cggaattgac gattggtgat ttgacgatcc atccagaagc ttacatggtg
     2581 acgaaacgag gagaaacaat cgagttaaca catcgtgaat tcgaactact cttttacttg
     2641 gcgaagcacc ttggacaagt gatgacaaga gaacatttat tacaaacggt ttggggttat
     2701 gattattttg gagatgtacg aacagtggat gtaactgtac gtcgtttgcg tgaaaagatc
     2761 gaagataatc caagccatcc aaattattta gtgacacgtc gtggtgtcgg ttactatttg
     2821 cgtaacccag aacaggagta attggatgaa aagaaaagtc cgcttttttc gatcagtcaa
     2881 ttttaagatc gctattacct ttattctgat tttattgatc tcgatcgaaa ttattggtgc
     2941 ctactttata cgtggtttag aacgttccac gatcaataca tttattaaag atatgaatca
     3001 aacggtggaa tcattagcaa caacaatcag cccggaattg aatcgaaaag ataatgcaga
     3061 tgatgaagag gtaaatgcga atatcaaaag atttattgaa aacagtgcga ctagcgatat
     3121 catcgaaata cgggtcgttg acgaaaaagg gatcatccga ggaacaaccg atgtcaatga
     3181 acaaagcgct gtgggaaaga aaaatgatta tgttgatatc aatgatttca cgactaaacg
     3241 ttatgttgct ttagataacg acgataaacg ggtgaatatc aatgttcaac cgatcctgtc
     3301 cccgaccggc gatgccgtta tcggggctct ttacgtcaaa agtaatatcg aacaaaaata
     3361 ttcggaaatc aataacacag cagtcatttt ctttactgcc tcactaattg cggcatttat
     3421 ttcaatgatc gtatctgttt tagttgctcg ttcgattaca cagccgatcg gtgaaatgag
     3481 agaacaagcc attcgaatcg ctagaggaga ctacagtcgg aaagtcaaag tgcatggaca
     3541 agatgaactt ggacagctgg ctgatacctt caatcagtta gctgaacgta ttgaagaagc
     3601 tcaagataca atggaagctg aacgcaatcg tttggatagc gtgctatccc atatgacaga
     3661 cggcgtcatt gcgacagatc gcaggggtaa agtcattacg atcaatgata tggctgtttc
     3721 cttgctagat atcaaaaacg aggaagcaat cggacaatcg attttgacac ttttagatat
     3781 cgaagaagaa tatacgttgc ggaaattatt agaagatcca aacgaaatgg tacttgaccg
     3841 ttcaaccagt acattggaaa gtgatcagat gatcttgcga gtagactttt ctatgatccg
     3901 tcgcgaatca ggttttatca gcggattagt agctgtcttg catgatgtga cagaacaaga
     3961 aaaaacagaa cgggaacgtc gtgaattcgt ctctaatgtt tcccatgaac ttcgtacacc
     4021 gttgacaagt atgcgtagtt atatcgaagc attgagcgaa ggtgcgtgga aagacgagga
     4081 agtagcacca aattttttga aggtaacgct agatgaaaca gaccgaatga ttcgaatgat
     4141 caatgacctc ttaaatctat ctcgcatgga tacaggtaat acccagcttc aattagaata
     4201 tgtcaatttc aacgagttag tgaattttgt tcttgaccgg tttgatatga tggtgggaaa
     4261 tcaggaaaaa aattataaga tccgtcgtga atttacgcaa agagatcttt gggtcgaagt
     4321 agatacagat aaaatcatcc aagtagtcga taatatcatg aataacgcga tcaagtattc
     4381 accagatggg ggaacgatta cttgtcgctt attagaaacg cataataacg tggttttaag
     4441 tatcaccgat caaggattgg ggattcctaa aaaagatctg aaccgagtgt tcgagcggtt
     4501 ctatcgagta gataaagcac gtgcaagagc acaaggtggg acaggacttg gattagctat
     4561 ttctagagaa gtgattaagg cgcatcgagg cgctatttgg gcagagagca aggaaggaaa
     4621 agggtcgact ttttatatct cgctgccata tgaaccttat gaggaggaat ggtgggaatg
     4681 agaatctctg aaaaagtcgt tcgtatagga ctcattttga tggttgcgtt aagcatatac
     4741 ttctcttatg caatctggct gagcccagca ggaaaaagtt caatcaacgt agatgagaca
     4801 aacactcaaa tgatcgagtc tcaaagcaat cgaaaaactt ccgaagtctt tcttccgctt
     4861 catgttacat ggcaccattc gggaatgatc caagaaacca acagtgaaaa tctcgtgtac
     4921 cgattgcaat tgatcatcga taaagcaaga tttggaaagc tttctgaagt agtttcagga
     4981 gacaaatcac agtttgaaca ggtgaaaaat ctgaactctg gttttgagtt ggcctataat
     5041 gcgccttttt tgctaagaga atacaaggaa gcatttgatt tagatttaga tgtgtcgaac
     5101 ttggcaaaag aaagcgaaaa tatgtatttt actagaatac aattcgatca aggaaataaa
     5161 aaaatccgat ttttgaatta ttcgaaccat ctcgtatatg aagcaaatat ttcgttgaat
     5221 tggacagata tcaataaaga attaacagca aaagacacaa aatggacaga aatgacaaca
     5281 gaaccatcga cgatcgacac gcaatatgct acgaaacatt cgatcaaact gaaaaagtat
     5341 agttatatcc tgtcacagca accctataca ctttttagaa atgctttttt ccagaaacca
     5401 gatagcgtga aaaataatga tgaaagcaat gaattgattt tttacggtgg gaatgaaaca
     5461 atgtctatcc attcggaaac gcaagtagtt gattttcgtg gagagctgcc agagaaaaaa
     5521 gaaaatgcta gtgtattttc tgaaagtttc ccctatatta gcaaattagg cagttcttta
     5581 gggaacctca gatattttga ccgcagtgac aatacgatcg attatcggat attcgtggaa
     5641 ggcttcccgg tttttgggac agacagcaga ggacagattg gtgtggaagt tggcggtgaa
     5701 acgaatggtt ctgtgcaagt gaatatccaa accagtttga atacgattca agtgccgata
     5761 ccttcagacg aagaagtaga acttgcaagt acgaatgaaa tcatccagca gttaaaagct
     5821 aagggagcag atagcaacaa gattggttca gtgatcgttg gctatacatg gcaaaatgtc
     5881 aaagaaacga atcgtgtcgt tgatctctta cctgaatggt atgtgaaata taaagataac
     5941 tggtattcag ctaacgacct tctggaaaaa ttacctggat tggaggcgaa ttaattggat
     6001 ttcaaaaaaa tcgaatggat atttttcgtc gcttttttag ggttgaatgt gtttttattc
     6061 agcagttatc atgacgcggt ataccaagaa aacaatgtca ttcgctctaa tcagactgaa
     6121 tcaatccaac aacgtctggc tagcgacgat atcacttaca cggggaagat ttcgtctgag
     6181 aacaagcaag gctattatct tagcgcggag cagaccaatc ttagcacttc attagcgaat
     6241 tatcgcaagg ctggtaaaag cggcttgctg gcaagtggtg tgtttttaga cggtgatgtt
     6301 ttgacgaaat ctttatccag ttcagatgct gaaaagaacg tgatcgatcc agataaaatt
     6361 agtagttcct tggaagattt tttatctaac aaagacaata ttttattcgg taatgattat
     6421 gtgtacacga aaaacttttc tcatttagaa gaagaaccac tagaaatcca agcaagccaa
     6481 gagtatgaag gcatcccatt caatgatgat acagcaaaaa tcgttctttc tttagaaaaa
     6541 aacgataatg attatagcat cacgaaatac atgcagacgc atttatctga tatcgagcag
     6601 ctgcgcgaaa agacggaact gtatacggaa gaggaagcaa tcaatacatt gtacatcaat
     6661 aacaaaatac caagaggatc aaaaatttta tggcgtcagc tagcttattc ctgtattctg
     6721 aaagtccggg aaaaaaatgt gtatgttcct gtttggcatg tagcgatcga aacaagcgat
     6781 aaagtggtcc aaattgagag tgtcaacgct ttcagcaata cgatcgtgac aaacaatact
     6841 gtaccaaaag tggaagatca ataaaaaagc gagtataatg aaaaaagttt acaaagtaag
     6901 aagggaagta ggagtcaaat ggctgaagaa aaaccagctt ttaaaatcag tatcctagca
     6961 agtggaagtt cgggtaattc actttatatc gaaagtgaaa aaaaacggct tttggtcgat
     7021 gcaggactta gcggtaaaaa aatcacttcc ttgatggctc aaattgatcg gacaccggac
     7081 caattagatg gaatacttgt gacgcatgaa catcgagatc atatacatgg cgtgggtgtc
     7141 ttggctcgta agtatcattt ggatgttttt gccaatcagc agacttggga agcgatggaa
     7201 ccactgattg gaaatgtacc agtggaacaa aaacatctat ttgagatggg gaaagtcaga
     7261 acattcggcg atatcgatat tgagagtttc ggcgtctccc atgacgcagc ggctccgcaa
     7321 ttttatcgtt tccataaaga aaatcggtca ttcgtcatgt tgacggacac cggatattgc
     7381 agtgattata tgcgaggtgt cattgaaaat gccgatggtt atttgatgga aagtaatcat
     7441 gatcttgaga tgttacgcat gggaccttat ccgtggaatt taaaacagcg tattttagga
     7501 gatagaggac atctttccaa cgaagacggt gcacttgtca tgactgatgt gatcggtaat
     7561 cggaccaaac gaatctatct tggccatctt agcaaggaaa acaatatgaa agaacttgct
     7621 catttaacaa tggaaaatgt tttgaaagaa aaagattttg gcgttggaca tgattttgaa
     7681 atctatgata cagatccaga tgaagcaact gagctatttt cgatttaaac agttcaatca
     7741 ataaaaatat aaaaagcaga agataaaatc aatcagggtt ggttttatct tctattttta
     7801 tttttttagc atattaaaaa aataaccgta ttatcgactg actacactga tgtgctgctt
     7861 ttcatgtttc tcatccagta tctcatctac taatgcaatc gcgtaatctg ccatgctgat
     7921 cgtactgtcg ccagcagcgt ttctttgtaa ataatcatca cttaacaaat aagtacctgt
     7981 acgtttgcca tgtggatcaa ataaagaagc tggactgata taagtccaat gtagattttt
     8041 agattgtttc aattttaaca atccttcgta catattgaaa gctgttggat agaagggtgc
     8101 atttttaggt acttggtcaa tcatacgagt cgtcttttct gtatctaaga ataacgaaga
     8161 ggcaccccca acgacaatta agcgtgtatc ggttccttca agcatctcaa tcaaatggga
     8221 caaagaagtt tgatgcattt cttcttttcc tttgggagcg ttgaaagcat caacgacaac
     8281 atcaaaagat gcaagatcag tagttgtcaa ctcaaataaa tccttttgta taaacggaac
     8341 atctgatggc aatttttctg gatgacgcac gattgccgtc acgtctaaat ctctggacaa
     8401 tgcttcgtct aaaataaatg aacctgcatg gccagtagct ccaatgagtg caattttcat
     8461 aaaaaacctc cttttttatt cctgtccatt gtaagcagtt gctgaatatt cgtcaaagaa
     8521 tccgattttt gaaaagctca gtgcgcattc ctttcatggt tcgtgatcat tgggtatagt
     8581 taaattaaga aaactgattg ataaaaatag aagttgaagg agataagaaa tgaaagagtg
     8641 gttagatcgt gcctttttac caatgataac atctgttgtg aatcttagac ccttaactgc
     8701 tttgcgtaat ggaatgactt acacgatccc aataattatt gttggctcgc tgtttttctt
     8761 atttgctcat tttcctgtgg attacatcgc tcagtggata gacaaaacag gattttctat
     8821 gtattttaca caagtatacc aggctacatt tgatgtgata gccttttgga tcgtttttgc
     8881 cattgcatac gcttatgcaa aagaagaaga catcgatcgc ttaccagtcg gcataacagc
     8941 cttgtctgct tatctactgc ttattcagcc actaaatact cagatagata ctgtctggac
     9001 aggtgctgaa gggatactag gagcagttac aactgggctc atcatcggat ggggctatgc
     9061 acgtttagta agacttgcga aagggtggaa gcaaagagag aagatacctg aaaatgtttg
     9121 gcagtctttt acttcattga ttccaatcat tgttatagtc acttttacgc ttatcggttc
     9181 agcggttttt caacagttgt tcagaatgac tgttgttcaa ggagtatgga catatgtcca
     9241 gcttcccatt caatcgttca tagacacgtt gtttggtgtg cttttattag gtttttttgt
     9301 tccgttttta tggttatttg gtcttcatgg atctgcgatg gtcaatgggt tggttagtcc
     9361 cgtcttgcaa gcgaattcat tagcgaatgc agaaatctta gcctcaggac aagagttgac
     9421 ggtggcaaat ggcggacata tcgttactca gcaatttctc gatcagttca tgacggttac
     9481 gggtgctgga ttgacgttag gggctgtatt ttttatgacg gtttttgcga aatcgaagaa
     9541 atacagagaa ttaggaaatc ttgctctttt accagccttt ttcaacatca atgaatcaat
     9601 tattttttcc acaccgatcg tgatgaaccc gatgatggct gttcctttta ttttcgcacc
     9661 ggtcgtttca ggattgatta cctattccgc tttatatttt ggattcgttc ctttatttac
     9721 agcagtccaa gtcccttgga caacaccgcc gatcctctcg ggtttcttag taggcggagt
     9781 gcctgcagcg attttacaag gtatcgtgtt gtcaattagt tttttcattt atttcccatt
     9841 tttgaaaaaa atagattctg caaactgcaa aaaggaaaga cagacaaaaa atgatggagc
     9901 agcagaaaag atgaacgact aaaaaacaaa aatactcctg tcgctttaga ttgggaaaat
     9961 caccaatcta ggatgacagg agtatttata gtcatgttta tactagccct ttttggacag
    10021 ctaattgaac aagaacaact aatgtgttca ttcctacgtg tgtgatcatc gatgtccaga
    10081 tccgaccagt tgctttgtac tctaggctga agaagaaacc taggaaaaag tagattagca
    10141 gatgaccatc attatgagca aacgcaaaca gcaaagagct gatcactgct ccgacccaaa
    10201 aatttgaata tcgactgatg atccccagta tactgcggcg gaatacgaac tcttccatga
    10261 tgggtccagc aacagttgtc gccaaaataa aagcgggtgc ttccatgatc atctggatga
    10321 tattttgtgt attctcggaa ggggttgctt tgccaaacaa tacagattct aacatgacag
    10381 cgatgctttg cagaatcaat gcgacaaaga ttccaaccaa tccataaata acaatctttg
    10441 gagcagaagc tttttttacc gctgattcga tcgctaaggg ttcacgttgc ttaaaataaa
    10501 aaatagctag gacaacggcg cctagtatat acatgactgc agttgctgtg atcaattcag
    10561 acgtagattt tacaagtcct atcgaagcta ggatcaaggg tgagataaaa attagaccat
    10621 agcaaaaaat gctgaggaag ctatattttt ttaaagacat gtaattcctc cttttaaggg
    10681 ataacaagca tgcaaggcaa gcttatatcg attgatttca attatatcat aatttcaata
    10741 agcagctgtc agaataaaat ttcttttctt tgatttaaaa gcttgcaaaa aagagggaga
    10801 atgagtatta ttaaaaatgt aggttagcac tcgaaggtta agagtgctaa cagattaaaa
    10861 aaagagttat cggagggatt tatcgtgtta aaaccattag gtgatcgcgt cattatcgaa
    10921 gtcgcaaaag aagaagaaaa aactgtcgga ggaatcgttt tagcttctgc tgctaaagag
    10981 aaaccccaaa ctgggacagt tgttgcagtc ggtgaaggcc gtttgttaga aaacggtgaa
    11041 aaagttcctg ccgctgtaaa agcaggcgac caagttatgt tcgaaaaata cgccggtaca
    11101 gaagtaaaat acgaaggaaa agaatatctg atcgtcgcag gaaaagatat catggcgatt
    11161 gttgagtaaa tttggaagat aaaaaaataa tcaaaaataa tcaatgaggt gaatcaatca
    11221 tggcaaaaga attgaaattt gcagaagacg cacgcgcagc tatgttacgc ggggtagata
    11281 aattagcaga tacagtgaaa gtaacattag gacctaaagg ccgaaatgtc gtactagaaa
    11341 aatcttacgg ctctccattg atcacaaatg atggtgtgac gatcgcaaaa gaaatcgaat
    11401 tagaagatca ttttgaaaac atgggtgcaa aacttgtatc agaagtagca tcaaaaacaa
    11461 atgatattgc aggagacggt acaacgacag caactgttct gacacaagca atcgttcgcg
    11521 aaggtttaaa aaacgtaact gcaggtgcta atcctctagg cattcgtcgc gggatcgaat
    11581 tggcaacaaa agcagcagtc gaagaattgc ataatatctc aactgttgtt gattcaaaag
    11641 aagccattgc acaagtagca gctgtttctt cgggttctga taaagttgga catttgattg
    11701 ctgatgcaat ggaaaaagtt ggaaacgacg gtgtcatcac aatcgaagaa tcaaaaggga
    11761 tcgaaacaga actagatgtt gtagaaggta tgcagtttga tcgtggttac ttatcacaat
    11821 atatggtaac agataacgac aaaatggaag ctgttctaga aaacccatat atcttgatca
    11881 cagacaaaaa aatctctaac atccaagata ttctgccatt gttagaacaa atcttgcaac
    11941 aatcacgtcc attgttgatt attgctgacg atgtagatgg tgaagcattg ccaactcttg
    12001 tattgaacaa aatccgtgga acattcaacg tagtagctgt aaaagctcct ggtttcggcg
    12061 atcgtcgtaa agcaatgctt gaagatatcg ctattttgac aggtggtaca gtaattactg
    12121 acgatctagg tttagaattg aaagatgtaa caatcgaaaa cttaggaaat gcttctaaag
    12181 ttgttgtaga taaagacaat acaacgatcg tagaaggttc tggagaaaaa gaagcaatcg
    12241 aagctcgtgt gcaattgatc aaaaaccaaa ttgctgaaac aacttctgat tttgaccgcg
    12301 aaaaattaca agaacgctta gctaaattag caggtggtgt agctgttgtt aaagttggtg
    12361 cagctactga aacagaattg aaagaattaa aattacgcat tgaagatgca ttgaatgcta
    12421 cacgtgccgc agtagaagaa ggaatggtct caggtggtgg tacagctcta gtgaacgtta
    12481 tcagcaaagt ttctgctgta gaagcagaag gagacgtggc aacaggtatc aagatcgttg
    12541 ttcgtgcttt agaagaacca attcgtcaaa tcgctgaaaa cgctggttat gaaggatcag
    12601 tgattgttga taaattgaag aacgtggaac taggcactgg tttcaatgct gctactggag
    12661 aatgggtaaa catggttgaa gcaggtatcg tagacccaac taaagtaaca cgttctgcct
    12721 tgcaaaatgc cgcttccgtt tctgccttgt tattaacgac agaagcagtc gttgcagata
    12781 aaccagaacc agcagcgcca gcagctcctg caatggatcc atcaatgatg ggcggtatga
    12841 tgtaagaaaa agcaacttgc ttatctacaa ctgatcatta gtgaaagaca gataaaaaga
    12901 ggctggaaca gaagcgttta actccaagaa ataagaagaa attcacggaa attgcttttc
    12961 aaatttttgt gaatttcagc ttatttccga aggagttgct tctgcttccg ctgtttatac
    13021 gtgtttagag cgtgagacaa aagtgttctt tacttttgtc ccacgctctt ttttgtgtgt
    13081 aattataatg aaaatagtta tttttaatag ttataatatt ttatctatta aaagtaaata
    13141 tccattca
//
LOCUS       DAIGSZ010000072        12900 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.073, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000072 DAIGSZ010000000
VERSION     DAIGSZ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.073"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(116..1564)
                     /gene="cls"
                     /locus_tag="NOB31_002345"
                     /pseudo
     CDS             complement(116..1564)
                     /gene="cls"
                     /locus_tag="NOB31_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
     gene            complement(1716..2609)
                     /locus_tag="NOB31_002346"
     CDS             complement(1716..2609)
                     /locus_tag="NOB31_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0974527.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2593..3279)
                     /gene="ftsE"
                     /locus_tag="NOB31_002347"
     CDS             complement(2593..3279)
                     /gene="ftsE"
                     /locus_tag="NOB31_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HCI0974528.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3384..4485)
                     /gene="prfB"
                     /locus_tag="NOB31_002348"
     CDS             complement(join(3384..4412,4414..4485))
                     /gene="prfB"
                     /locus_tag="NOB31_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HCI0974529.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4611..7145)
                     /gene="secA"
                     /locus_tag="NOB31_002349"
     CDS             complement(4611..7145)
                     /gene="secA"
                     /locus_tag="NOB31_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HCI0974530.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            complement(7367..7918)
                     /gene="raiA"
                     /locus_tag="NOB31_002350"
     CDS             complement(7367..7918)
                     /gene="raiA"
                     /locus_tag="NOB31_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HCI0974531.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(8046..8765)
                     /locus_tag="NOB31_002351"
     CDS             complement(8046..8765)
                     /locus_tag="NOB31_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HCI0974532.1"
                     /translation="MRCSCCSKDIFQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            complement(8762..10075)
                     /locus_tag="NOB31_002352"
     CDS             complement(8762..10075)
                     /locus_tag="NOB31_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCI0974533.1"
                     /translation="MNHFWGRRLLTRDIEAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            complement(10156..10476)
                     /locus_tag="NOB31_002353"
     CDS             complement(10156..10476)
                     /locus_tag="NOB31_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0974534.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            complement(10584..10871)
                     /locus_tag="NOB31_002354"
     CDS             complement(10584..10871)
                     /locus_tag="NOB31_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974535.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            10998..11642
                     /locus_tag="NOB31_002355"
     CDS             10998..11642
                     /locus_tag="NOB31_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HCI0974536.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            complement(11701..12408)
                     /locus_tag="NOB31_002356"
     CDS             complement(11701..12408)
                     /locus_tag="NOB31_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0974537.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(12628..12798)
                     /locus_tag="NOB31_002357"
     CDS             complement(12628..12798)
                     /locus_tag="NOB31_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974538.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
BASE COUNT         3566 a         2796 c         2243 g         4295 t
ORIGIN      
        1 taatttcgct catgcgagac gctttctcca tttctgacgt actctcagaa atggccccgt
       61 tagaaaagga cacgagatct ccatctgttg atggttctca tgtccttttt atgttttaaa
      121 ggagcggcga aatcaatctt gctaatcctt ctttcatctt gatgattatt cctcggtttt
      181 catacatttc ttttgtgaga tgcgtagaaa ttttcgagtc ttcaaaaaaa gcttttctta
      241 cacgtgaagc cattcgttca tcataaacca gtgtattgac ctcaaagtcc aagcgaaatg
      301 aacgaacatc gatatttgct gagccaactg aaacaatgcc accatcgata atcatcgtct
      361 ttgcatgaat aaatccattc tcatatgttt cgatccttgc tccatactcg atcagctctg
      421 cagcgaaaga atacgttgcc cagtaaacga gaagatgatc tggtttgtta ggtatttgga
      481 tatgaacttt tacgcctgaa agaagagcca acttcagtgc ttcatgaatc gatccatccg
      541 gtatgtaata aggcgtttgg atcaatatct cccgtttggc taacgaaatc attttcaaat
      601 aagtcatttt gatttgttca tgttcggtat ctggtccgct tgtcacgatt tgaacagcta
      661 tatcaccagt agtgtgaatg gacggaaaaa atttgggaga atagcctact tcttttgtat
      721 gctgagaatt ccagtccatc aaaaaacggt tttgcaaggt atacaccgct tctccgtaaa
      781 tacgcaaatg attgtctcgc caataaccaa atttctttac caatcctaga tattcatttc
      841 caacattgaa cccacctgta tatccgattt tcccatcaat aactacgatt ttacgatgat
      901 tgcgataatt gatccgagga ttaatatacg gaacaaatag aggaaagaaa aatgcgactt
      961 ctccgcctgc ttttttcaaa ttctgaaaaa agctggaaga aacttgtgtg gaaccccatg
     1021 catcaagaag gactctgact tttacccctc gtcttgccgc ctctgtcaat gcatctcgaa
     1081 cttcttcacc taatgcatca ctgcgataaa tataatactg gaagtggata tggtcttctg
     1141 cctgcttgat atcttcaatc agcgcatcga atttttcacg accatctgta aataaagtga
     1201 tttcattttt agtcgtatag agcgtacttt caaataccgt gagcatatag atcaattgtt
     1261 tcacatctac ttgtccagta ggcggatgag gataaagccc tcgcatcaat gcctgtttgt
     1321 cttcttcaat ttccaggttc ttaccgattt tcccttggat cttcaaatca aagattttct
     1381 ctttggaaat ccctcttcct aaaaaaatat ataaaataaa tcctacaact ggaatgaaca
     1441 tcaaaacgag cagccatgcc catgtttgag cagtttcctt tctttatcga aaaacgatga
     1501 taaaggaaag caaaatattc ataatcaaaa ggatcgtaaa aaaattgtca acgataattt
     1561 tcacggcttc acctcttctt ctaccaactt aagaataccc aagttgtttt ttaaagtaaa
     1621 gggaaaaaag ccgcttcctt ctattctcct agccaataaa aaaagaaagc tggaacgaaa
     1681 ctgtccaact ttctcatttt atttatattg tggtattaga atttcaagaa acgtctcata
     1741 gaaatgatcg agccaagtga accaatgatc acaccaatgc cgaccattaa aagattgatt
     1801 ttccaaacga tattttgtgg atgaatcaat gaataatggg aacgtaataa tgatggattg
     1861 atcaattgga aaaaccatgc ataaccaaat gtgatgatca aaatcggaag aatcgcaccg
     1921 atcagaccga tccagccacc ttcaaggaaa aacggccagc gaatatatcc attttttgca
     1981 ccgactaaac gcatgatttg aatttcacgc tgtctagaca aaatcgtgat ccgaatcgtg
     2041 ttcgaaatga gaaacatcgc tacgaacagc agcaatgccg ctgcaactaa tccccatgtc
     2101 cgaactgcac cagcgatttg gaaaatccga tctgaggaag ctccaccgta atcagaacga
     2161 gaaacattct tcaaatctgc tgcttcttct gctacttgtt ttgtataaga aggatcagta
     2221 gcacttacta catacacatc atataacggg ttattgtcac cttcaaacaa tttccaggaa
     2281 tcacccattt cgttttggat ttttttcaat tcctgttctt tgcttgaaaa ttcaactttt
     2341 ttaacatgat ctaagtcatt caattctttt tctagctttt tcatctcttc gtcttttgta
     2401 ccgatatcta cgaatacaga tacatcaacg tttccttcta tatcctgagc taatttagtt
     2461 gcattcatga taactgccat gaatacaccg actaaagtca acgtgatcgt taccgcactg
     2521 actgaagcaa ctgtcatcca gccgttacgt ttcaaactct tgatactttc taataaatgg
     2581 cggaaaaagg ttctaatcat cgtatccata ttccccttcc gcttgatctc gaataatgcg
     2641 gccgttttcg atagcaatta ctcggtgccg aatcgtattt acgatcgtac tgttatgtgt
     2701 agccatcacg acagtagttc cttgggcatt gatccgatct aataatttca tgatttccca
     2761 tgagttttct ggatccagat ttcctgtcgg ttcatccgcg ataagtactt taggcgtatt
     2821 cacgattgcc cgagcaatag agacacgttg ctgttcccca ccggataatt cgctaggaaa
     2881 gactcgaact ttgtgtttca aaccaacaag gtccagcact tccattactc gttttttgat
     2941 atctcgaggt tttctgccga taacttgcat agcgtacgca acattttcat atactgtttt
     3001 tcttggtaat aatttatagt cttggaacac cacgccgatt tctctgcgta gataaggaac
     3061 ttcgcggttt ttgattgcta ttagatcatg acctgcgacg ttcaaagttc cttttgaagc
     3121 tttttcttct cgatacatca atttgatgaa tgtagattta ccggctccag acggaccaac
     3181 cacatagaca aactctcctt gttcgatgac aatcgagaga ttgcggatag cggtcgtacc
     3241 atttgagtac ttcttcatta catccttcat ttcaatcatg gcgttctctc catatctttt
     3301 tcagtcttta gctattatag catggcaatg tttcaacatg cttgcaaaat cttacaattt
     3361 tatttcaatt taacaatgag ttcttattgt agatgcattt ttaaatagcc gtcaataaat
     3421 aaatcaaggt caccgtccat aactgcttgg acatttcctg tctctacgtt tgtccgatgg
     3481 tcttttacca tagaataggg atggaaaaca taagaacgga tctgtgaacc ccagccgatt
     3541 tctttttgtt ctcctcgaag tgcagctgct tcttgttctt tcttttccac ttctaattga
     3601 taaagcttag cttttaacat ccccatcgct tgctcacggt ttttcaattg tgagcgttgt
     3661 gcctgactag ctactactgt tcctgtaggc aagtgagtga tccgtacagc agattctgtt
     3721 ttattgatgt gctgaccacc tgcaccactt gctcggtacg tatcgatttt caaatcatct
     3781 ggattgattt ctatatcgat cgtttcatca agctctggca tcacatctac cgaacaaaaa
     3841 gaagtatgac gtcgtttcgc tgagtcaaaa ggcgaaatcc gtacaaggcg atgaacacct
     3901 ttttctgatt ttagataacc aaaagcgtta tgtcctttaa tcagcagggt cacactcttg
     3961 atccctgctt catcacctgc ttgataatct agtgtttcta cttgatagcc atgctgctct
     4021 gcccaacgtg tatacatacg taaaagcatg ctgccccagt cttgggactc cgttccgcca
     4081 gcccctggat gcaattcgac gatcgcattg tttcgatcat aaggtccgtc taacagcata
     4141 gataattcat acgtcttcat tttttcatct aatgcattga tacgtgtttc tgcttcttct
     4201 tgcattgctg catcaggttc ttcttgcagc atctccacca tcaattcgat ttcttctagt
     4261 tcttcggcaa gagaatggaa ttggtcatag gtttctttat tagcgttatt ttcgctgatc
     4321 actttttgtg cggcttcgct gtcatcccaa aaaccaggtt cagccatttt tgcttctgct
     4381 tccgcgatgt cttcttccag ctgatctaag tcaaagagac ctcctgaaac ttgtgacctt
     4441 ttcctgcatt tctgtcagga gatttcgaat ttcggatatt tccatgtttt ttccttcttt
     4501 cactatactt ttttcattat atctagtcta acagaatcag caaataacag aaagaaggtg
     4561 agacgaattc ttaaaaaaag aatttgtctc accaatcctg ctgtcagaaa ttagtttgca
     4621 ttttttccat gacagttctt atattttttc ccgcttccac aaggacaagg atcatttctt
     4681 ccgaccttgt tcacatggat tggctgtttt ttcgcgctag tattactatt ttctttggca
     4741 tctccgtctt ctgagtgaga agctgttcct tgagaaacct gttcacgctg tacgttttga
     4801 cggatctcag ctttcataaa gattcgagtg acttcatact cgatggcgcc taccatatct
     4861 tcaaacatct tatagccttc tgtttgatat tcgactaatg gattgttctg tccataagca
     4921 cgtaagccga ttgactgacg taattgatcc attgcatcaa tatggtctgt ccatttagag
     4981 tccacaacac gcaagatcac gactttttca aattccaaca gttgctctgg accatttagt
     5041 tgagccgctt tggtattaaa tacttcttgt gctcgttcgt ttagatactc tttgatctcc
     5101 tgagatgttt ttccttcgat atctgcaaga gtaatactat cttcatggac aagagtactg
     5161 ccggcaaaat cgatgatact ttccaaattc caattttctt tctctaattg tgtatgcgca
     5221 tctactacac gactgattgt ccgtttgacc atgttcatta gtggcttgga taagcttttt
     5281 tcttccatga ttacttcttg tcgctgttta tagattactt cacgttgttc acgcatcaca
     5341 tcatcgtatt gtaagacgtt tttacgtgtg tcatagttat ttccttctac acgtttttgt
     5401 gcagattcta cttgtttcgt cagcatcttg ctttggataa cagcatcttc ctcaccgatc
     5461 ttcatccgat ctaagaaagc tttgattcgt tctgaaccga atcgtttcat caaatcatct
     5521 tccaatgaca agtagaattg tgacatacca gggtctcctt gacgtcctgc acgtcctcga
     5581 agctggttat cgatacgacg agattcatgt cgttctgtcc cgataactgc tagaccacca
     5641 agttctctta ccccaagtcc taacttgata tctgttcccc gaccagccat gttggtagca
     5701 atcgtcacag cacctttttg accagcattc atgatgatct ctgcttcttt aaagtgattt
     5761 ttcgcattca gcacttcatg aggaatacgt tcttgattca gcatatctga taataactca
     5821 gatgtttcaa ccgcaacagt tccgactaac acaggttgac ctttgcggta gcgatctttg
     5881 atatcttgca cgacagcgtg gaacttgctt tgtaatgttg ggtaaagtaa atctggacga
     5941 tcatcacgga taaccggacg atttgtcgga atctggtata cttggatgtt ataaatttct
     6001 ctgaattctt cttcttctgt tttagctgta ccagtcattc ccgcaagttt cttgtacata
     6061 cggaaatagt tctggaaagt gatcgtcgcc atggttttcg tttcgtcttc gatctctacg
     6121 ccttctttag cttcgattgc ttggtgaagt ccatctgaat aacggcgtcc atccatgatc
     6181 cgaccagtga actggtcaac aatcagtact tttccgtctt ggacaacata atcgatatct
     6241 aaaagcatga tatagttggc tctcaatgct tgatccaagt gatgggtcaa tgcagtattt
     6301 tcaatgtcgt ataagttatc caaaccgaat gtttcttctg ctttttcgat ccctgcttcg
     6361 gttaaactga ttgtttttga ttgtacatcg attttataat cttcttcttc tttcaaacgt
     6421 ttcacgaagt tgtctgctct tgtatataaa gctgtggatt tttctgcttg ccctgaaatg
     6481 atcagcggcg ttctcgcttc atcaatcaag attgagtcaa cttcatcgac aatggcataa
     6541 ttcagcggac gttgtaccat ttgatggcgg taaacgacca tattgtctct caagtagtca
     6601 aatcctaatt cattattcgt actataagtg atatcacaat tataagcctc gcgtttttca
     6661 tccgaagatt ttgagttgat attcaacccc actgttaatc ctaagaaatt ataaagttcg
     6721 cccatttccg tcgagtcacg ggttgctaaa tattcattga cggtaactac gtgtacccct
     6781 tcgccagtca gagcatttag atatactggc atcgttgcgg tcaaggtttt accttcacca
     6841 gtacgcattt cagggatatt tccatcgtga agcacgattc cacccatcaa ttgtacgtgg
     6901 tatggatata accccaatac acgttttgct gcttctcgga cgactgcaaa agcttccgga
     6961 agtaattgat ctaatgtttc tcctttttgg tatctgccct tgaattcagc agtttttgcc
     7021 tgtaattgtt catcagttaa tgctgccatt tggtcagcgt atgcttcaac tttttttgca
     7081 atgctatcta aacgttttag ttctttctta tcgttttcga taagtgaacg aatcaaattg
     7141 gccatgcgtt gtgtaatctc cttttccttc tgtgtattat ccagactatg tagactttac
     7201 ttttcatttt atcattagtt atagataatt gaaatatctt aagcgtatta aagtaagaac
     7261 ttcataattt attcatattt catctaaaag aggaggaaac tcaaaaaaac ttgcggcagc
     7321 tgtcagtagc tgctgcaagt tttcgttgtt atttaagtaa ggctgatcag tctgtttcaa
     7381 tcagtccgta ttttccatct ttacggcggt aaacgatact tgtaccattt gtttctgcat
     7441 cttcaaaaat aaagaagtta tgtcccagca tgttcatttg taagactgct tcttcactat
     7501 ccattggttt caatgaaagg cgtttcgtac gtacgatatc taattcagaa tcattttcgt
     7561 tttcgtcctc ttcattgaat aaagcagcag catctgcagt attcatgccc gtttcacggg
     7621 atttacgatt aatttttgtt ttgaatttgc ggatttggcg ttccaattta tcaacaacca
     7681 aatcgatact tgcgtataaa tctggagaag tttcttcggc acgtaataca agataaggta
     7741 atgggatcgt tacttccact tttgctgttt tttctgtata aacttttaag ttcacatgcg
     7801 ccgttgcatc gggtgcgtca ctgaaatagc gttctagttt gcctactttt ttctcaacgt
     7861 agtcgcgaat cgcttcagtt acttcgatat tttcgccgcg tacattatat ctaaacataa
     7921 aaattacccc tttcgtctac cacaatcaag aaggagaagg accactcttt ccctcttctt
     7981 aattctatta tatcgaactc taggttattt gcaaattaaa tcgctatcaa atttccacat
     8041 ctaattcatc tcgccaaaga aatggttcgg atgattttcg gctgtgcgac ctgcaaacaa
     8101 tctgctgcgt ggaaaagagt ctgtcctgtt gtatagacat catcaataat caatattttt
     8161 ttattttgta tcttagaaaa ggtgactgca agttcaaaag gttgaggcat ctccaatctt
     8221 tcctttcgcg tgttttttgc ttgagccagc agatgcttct ctcttttgag tagcatctga
     8281 aaaggaattc ttgctgcttt caacatctcg cttacttgat tgaatcctct ttctgttcgc
     8341 cttttttcag ataaaggtat tggacaatag atgtatgtcg ggtattcttt ttttatctgc
     8401 gtccatttat atgcaaaggt gcctgctagt cggatatctc ccataaactt gtattgattg
     8461 agccaggcct tcatattttc atcgtacaca aaaaaggcac ggtgctgaaa atcataggtc
     8521 ggatatttct tcttccattc ttgacagtca ctgcagtaaa cgggaataga ctttactttc
     8581 tttttcgtac tctctagatt gaaatggatt ggtttttgac agccagaaca gcctcttgtt
     8641 tccaataaat gaaattgtgc gcgacaaact gaacaagtct gaggtaatct gtatttcgaa
     8701 acaccaataa tctcgctgaa tgttaaattt tggaagatat ctttactgca gcaactgcac
     8761 ctcacagcat cttcttccct tcttcattca tttctttgat ttcctgacaa gcttttcgaa
     8821 tagctgcagt tttttcttca tagaaaaagt atacttgact gttcgtataa ggccctttac
     8881 gatcggctct tcctgcgatt tgtaccaaag aagatttagt aaaaaccgga tgatccgctc
     8941 ctaaaacgat aacggatatt ctttcaaatg tgactccacg ttcaaggatc atcgtggtta
     9001 acagtatatc atattttgct tctcgcattt tctggacttt ttccgcccgc tgattgtctc
     9061 ttgaagaaac atctgtgatc tcatatctcg gaagagcctc ttgaagtgtg gctttcaaac
     9121 gatgcatcat cgtgatactt ggacaaaata aaaggatatg gttttcttta attaattgat
     9181 gaatgatccg caccaaagat tttatcttct tcttgttctt gcatttttgt cgccaattat
     9241 tcatgaaaac caagacgggt tcaggaagca aacgccgatg aaagcgtaaa gcaagtttgt
     9301 ggatgtcaaa cgtctgcttg atttccttta gtaacttttt atcaggtgtg gcacttaagt
     9361 agatgaatcg tccgtctggt ttaatcgctg tttgcacagc atgagctaat cctgcatccc
     9421 cgttataagg aaacgcatcg atctcatcga tcactattaa atcaaaggac cgataaaaac
     9481 ggtatagctg atgaatcgta cagataacaa aagaagtaaa ggtataagcc gttgctgtat
     9541 tcccatggag caacgtgatt ttttcttctg gaaaaacata acgatagcgt aaaaacaatt
     9601 cattacaaac atcgactcgc ggtgtacaaa tcgctactct tcctccagct tttaaagttt
     9661 ccactaaaat aggataaagc atctctgttt tccctgcacc tgttacagcc caaataagat
     9721 gatgtctttt ttctgaatgg caaagtattc tctttgagat ttccgtttgt ttttcagtaa
     9781 gctgtcctgt ccaaaaaaag acgacttctc gaggttttgc ttcaggctga tcaaacaaat
     9841 ataaatcttg ttgagtgtcg catcgcccta aatatagaca atgtgtacaa aaataaccgt
     9901 aatctgcaag ctgtccatca atgacggacg tcctcattcc acagcgatga caaagaatcc
     9961 agttgcccaa acgttccact gctgcgatct tctcataatt tggtaaattt acctcctcac
    10021 agtctattgc ttcaatatct ctcgtcagaa gccttctacc ccaaaaatga ttcatattct
    10081 tcgccctaaa aaaatatacg aaaaaacaag cgatctattt tttggatcgc ttgttcgata
    10141 gttatactgt tctatttatt cacctatgag cgtgattgct tgatctaaca ctttttcgcc
    10201 attcatcata ccataatcag ccatattgat gacatctaaa ggaatgcctt ttggttccag
    10261 acgtttctca aaatcagctt tcataaagcg aacttgtggg cctaataaca acacatccac
    10321 gtctttattt gcaaggttgt tatctgcgtc agaagcggac acagcgaaaa tatccgagtc
    10381 gattcctttt gcttcagcag ctttttgcat ttttgttact agtaaacttg tgctcatacc
    10441 agccgaacat acaagcatga ttgttttttt agccatactt ttctctcctt tttaaaacaa
    10501 actatgcaaa cgttttcttc gcgtctgtta ctctattata taaaaagaaa gaaatttgtc
    10561 aacgttttct aaacgcggtt tatttaatca aatagccaac tagatttcac taatttattg
    10621 aacacgacat attctttgtc caaattgatg acaactactt catagcctgc atttatccag
    10681 ccataggcac ctttttcagg gtgtttataa tcatttgccc accaatctgt actttccctt
    10741 gctgttttgg gaagtccgtt actgggaaac agcagttcgt caaattgggt aaaggtcaac
    10801 gttacttgag agccgccatt gttcttcaaa taatgcgtaa ttgcatcgta ctttttcatt
    10861 cgttcctgca tccccagatc cacctgcctt tgtctttatt atcgcatact acagcaattg
    10921 cgcaaccgtt acagtgttga aacaacctag aactttattt atactgaata aagaaaatga
    10981 aaaaaagagg tgacaagatg atcgagcgct atcgtacaat aaaagaaaat ggacaaagtg
    11041 agattgagat caaaaaatca cgctttatct gttctcttag acgaatagaa tcagaggacc
    11101 aagcaaaaag tttcattcaa gaaataaaaa aagaacattg gaaagcgaac cataactgca
    11161 gcgccttcat cattggagaa aaaaatgaaa tccagcgaag cagcgatgat ggagaaccaa
    11221 gtggaacggc gggcgtaccg atgttggaag tcctcaaaaa aaatcaactg atcaatgtag
    11281 ctgcagtagt cactcgatat tttggaggaa cgaaactcgg cacaggcgga ttaatacgag
    11341 catacactca tgcggtctct caagcattgt ctgacattgg aatcgtagaa ggtaccttgc
    11401 aacaggagat ctctgtgatg atcacgtatc cgcaactagg aaaattacag aattatcttg
    11461 aactccaaca tttttttata aaagaaatcc aatatactga tcaagttagc gtcatctgtg
    11521 ctgtagatga aaaaagtgct gaccacttta aagaatccat cattgagctg ctgaacggac
    11581 aagtccaatt tgaagagggt tctgtttctt atcacgagca actgataact gatcatatat
    11641 aaaaacaggt gattctgatt ctcttttatt tctaataagg aatcagggat cacctgtttt
    11701 ttatttttcc aaataaaact caaaacgatt tcctacgtat tgcgtacgca catactcaaa
    11761 cggcgtaccg tcttcaaaat aagaaatctg gcgcaaacga agaactgcat ctcctcgttt
    11821 tacctctaaa tagtcagcaa ttttctcaga agccaacaca gcagtaatcg tttgattcgc
    11881 tggaccgatc tttttcccgc ctttttcttc tagcgtgcga tacaacgatt cagtaatctc
    11941 tgctttgctg tagccatcga tcagcttttg tggaacactg gcaacttcaa aacaaatagg
    12001 gacatcatct gcgaaacgaa tacgttccat tcgcaagatc gtgtcatctt tactcaagtt
    12061 tagtttttcc atttcacttg agcttggcga agtcaagaaa taagagattg tccgactaga
    12121 cggtactcga ttttgtgatt ccataatttc tgtaaaactt gttgcaccag acattttttc
    12181 ttgtactttt tctcgcgcaa catacgtacc cgaaccgatc tttctttcta agattccttc
    12241 atctgccaag ttttgaattg cttgtctcaa cgtcatacgg ctgacattga atttcactgc
    12301 taattctctt tctgaaggaa gacggtctcc gactttccat ataccctgtt cgatttcatt
    12361 ttttaattgg tcatgaatct gtatatatac aggtaattga ttcgacataa cgtacacccg
    12421 tcctttcgtt tcttctatta taactggtat atacctgatt cacaactgaa aaagataaag
    12481 gtttctatcc atcaacagag gatttagaca cacatcgttc tccctactcc tattgtcaga
    12541 aacaattttt tagatatgtt caacctagaa aataacaaaa gaccctaaaa tcgatgaaaa
    12601 tgccgactta tggatctttt gttattatta gcggttttta gccatccatt tttttgtatg
    12661 attcgttggg cgttttgatt ttacctggac cgcttttccg ccttttttcg gaatattcac
    12721 ttcaatattg tatttttctg atttgaccaa atcatataac ttttcagctg cttcgtctac
    12781 tttttctttc catttcatgt ggatccctcc aattcttgta gttaacttaa ctctatctta
    12841 attcagcaga atcttcaagg aacaaggtag caaagcaaaa aaaagagctc tcgaactaac
//
LOCUS       DAIGSZ010000073        12738 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.074, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000073 DAIGSZ010000000
VERSION     DAIGSZ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.074"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="NOB31_002358"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="NOB31_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCI0974539.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="NOB31_002359"
     CDS             complement(323..892)
                     /locus_tag="NOB31_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HCI0974540.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="NOB31_002360"
     CDS             1078..1980
                     /locus_tag="NOB31_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0974541.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="NOB31_002361"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="NOB31_002361"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HCI0974542.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="NOB31_002362"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="NOB31_002362"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HCI0974543.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="NOB31_002363"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="NOB31_002363"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HCI0974544.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="NOB31_002364"
     CDS             8548..8733
                     /locus_tag="NOB31_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HCI0974545.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="NOB31_002365"
     CDS             complement(8795..9991)
                     /locus_tag="NOB31_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCI0974546.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="NOB31_002366"
     CDS             complement(10161..11597)
                     /locus_tag="NOB31_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCI0974547.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="NOB31_002367"
     CDS             11890..12699
                     /locus_tag="NOB31_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0974548.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3803 a         2673 c         2250 g         4012 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgacaatt
//
LOCUS       DAIGSZ010000074        12735 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.075, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000074 DAIGSZ010000000
VERSION     DAIGSZ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.075"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            94..537
                     /locus_tag="NOB31_002368"
     CDS             94..537
                     /locus_tag="NOB31_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0974549.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(543..1727)
                     /locus_tag="NOB31_002369"
     CDS             complement(543..1727)
                     /locus_tag="NOB31_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HCI0974550.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            1995..2693
                     /locus_tag="NOB31_002370"
     CDS             1995..2693
                     /locus_tag="NOB31_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCI0974551.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2700..3377
                     /gene="nth"
                     /locus_tag="NOB31_002371"
     CDS             2700..3377
                     /gene="nth"
                     /locus_tag="NOB31_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HCI0974552.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3503..4036)
                     /locus_tag="NOB31_002372"
     CDS             complement(3503..4036)
                     /locus_tag="NOB31_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974553.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4333..6714)
                     /locus_tag="NOB31_002373"
     CDS             complement(4333..6714)
                     /locus_tag="NOB31_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCI0974554.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6704..7351)
                     /gene="recU"
                     /locus_tag="NOB31_002374"
     CDS             complement(6704..7351)
                     /gene="recU"
                     /locus_tag="NOB31_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HCI0974555.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7415..7954
                     /locus_tag="NOB31_002375"
     CDS             7415..7954
                     /locus_tag="NOB31_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HCI0974556.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8044..8463
                     /gene="gpsB"
                     /locus_tag="NOB31_002376"
     CDS             8044..8463
                     /gene="gpsB"
                     /locus_tag="NOB31_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HCI0974557.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8485..8852
                     /gene="rnpB"
                     /locus_tag="NOB31_002377"
     ncRNA           8485..8852
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="NOB31_002377"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9061..10227
                     /locus_tag="NOB31_002378"
     CDS             9061..10227
                     /locus_tag="NOB31_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HCI0974558.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10273..11769
                     /locus_tag="NOB31_002379"
     CDS             10273..11769
                     /locus_tag="NOB31_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HCI0974559.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11850..12533
                     /locus_tag="NOB31_002380"
     CDS             11850..12533
                     /locus_tag="NOB31_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0974560.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2229 c         2630 g         3603 t
ORIGIN      
        1 tggtttcaga ttgggttttc ctacaaaata tttttatctt tgttgaatag gaaacaaaaa
       61 aacaatataa tgaaagaaaa agaaggtgta gaaatggata aaagacaact gctaatagaa
      121 gaatatctgg atttagctaa tgagattatt catcgtaata aaccagaaat ggaaaaagaa
      181 tttgcaggat ttactctaaa tgaactagaa gtgattgaac atatcgggaa aatccctgat
      241 cctaacgtga caaaattagc gaatgctagt tacatgacta gaggagccat cagtaagcta
      301 acaaaaaaac tgatagctag agggatcata aacacttatc aaagcgaaga gaataaaaaa
      361 gaaatctatt ttcaattgac gccaatcgga caaaaaataa ggaatagaca cgagcaactc
      421 catcaaaaat gggtacagcg agatgctact gtatttgaaa atatgtcaaa agaagaattt
      481 gacacagtat ttcgttttat cggtcgatac agagaattta tacgaagtag caaatgaagc
      541 tactattttt tattgtagtg ataataggca aaaatcataa gcaaaaatcc gaataccgtc
      601 ggaagaaatg gtgctgcagc ataaagctgt cctgcgatta gcgggccgat gacgcgcgat
      661 agagattgta tactttgggt accgcccatt acaagacctt gctggttatc tgagacagaa
      721 ttggatagtt ggccattgaa tacaggagta aaaatagaat caccgaaacc ataacagata
      781 atcccaaata aaaacaaaat cggcagtaga agaattccag ataatgtgat gaatagatag
      841 gcgaggattt cactgaacat ccctattctt gtgatctgct gttctgaaaa ttttttgagc
      901 aatcgaggca taatgaacaa ttgcgagaca gtatccaaga ttccaatcaa agagaagctt
      961 aaaccaacca acccagcctt ccactgaaag gcgtcaatcg aaaattgaga aaagatagat
     1021 tgaagagagc cagctgccaa ccaaacagca aaacctgctg tcaataaagg aataacggat
     1081 gaaatcttga ataattgttg taattggtga aaaggtctta catgggagaa acttaaatct
     1141 actgaacgtt tttttattgg aaggctttct agcataaatg tgtagccata aacggcattt
     1201 aagaaagtaa agagtgctcc aataaatata ggaacagaat tccccaactc agctaataga
     1261 ccccctataa taggacccag cgttgttcct ataccgacta aagcacccat ccatccaaaa
     1321 actttggttc tttcattagg ttccgtgatg tcggcaaagt aagcatataa ggtggagatt
     1381 tctcctgccg tcaatccttc aatgatacga ccaaggaaca acatccatat cgaatttcct
     1441 aaaccaaaaa gcaaatatcc gatacttgat cctaataaac tgataataag gatcggatga
     1501 cgcccaaaat gatcacttaa gctaccgaga atgggggcag ataagaaggc agctagagca
     1561 taaacagaca tgagcaaagt gatatagaaa gcttgctgat gtatggagtg agaataaggc
     1621 agcgttaaaa acggaagtac aggactgacg atagtaaatc ctaatccagt gaataagaca
     1681 gagacgtatc caaaaacttt agaatgttta tttgtgaaac tgtacatgta aaaactcctt
     1741 tatgcaataa tgttaacttg gaaacaaaaa tagtgtatag taattttgtt tccttgtcaa
     1801 cattctaagg aacagcgaaa tctacttaat ttatttattc cgaaaagtga agatacgcat
     1861 caaaaacatg aacaaacaaa aatcaagtag acgacattgt aaatctgacc gatcagtgaa
     1921 gtaaatagaa aagaaacctg ttcttgcttc ccatgttttt tttacgtata ctgtgattga
     1981 gcggaggaga aatcatgttg aatttagaaa attacttaag cgctggacaa acagtcatat
     2041 ctaatctttt acttaaaaat tatcatagga tcggtctaca atctgaagaa tttttatttg
     2101 ttctacagtt gcatatggca cagcttgaag gagatacttt ccctgatttg cagatgattg
     2161 ctatggatat gggaatcaaa caagatcaga tttttcaaat actggatcgt ctcgtaacaa
     2221 atggatttat caagatagaa acgacgattg tcaacggtaa aaaagcagat cgatataatc
     2281 tttaccccat ctatgatcta ttaggtgagt atttaaaaac acaagaaaaa aaatacgaag
     2341 aaaaaacaca agaaaaagaa atccagtcag tgtatcaatt atttgaacaa gaatttggac
     2401 gcccgctttc ttcgatcgag ttccagcgga tcggacaatg gctagaagaa gaccattatc
     2461 agccggaaat tttgaagcta gcactgcggg aagccgtatt aaatcaggct tatagtttta
     2521 attacgttga ccgcattttg ctatcgtggg aaagaaaaaa tctacgtaca aaacaacaag
     2581 tggaagaaga ccaaaaacga agaaaacagc agcttcttca aagagaagta gaacagtcag
     2641 ctcaacaaga agaattgccg aaagtctcac tgaaaaattg gttggaggag tagcggaata
     2701 tgttaagcaa acaaaaaaca atggaagctc tagaaacgat gtatggaatg tttcccgaag
     2761 cacatggaga actcaagcac aataatccat ttgagttatt gattgcagtg atcttaagtg
     2821 cccaggcgac agatgtatca gtgaataaag caacgccaga tttgtttgcc tcttttccga
     2881 cacccgatgc gttagcagaa gcttcaatcg atgaaatcat tcttaaaata aaaacgattg
     2941 gtttgtatcg aaataaagca aaaaacatca aagcgtgtgc acagcagctg attgaacgtt
     3001 tcgatgggca agtgccaacg tcaagagaag aattgatgtc tcttcctggt gtaggcagaa
     3061 agacagcaaa tgtcgtattg ggggatgcat tcgggatacc agcaatcgca gtagataccc
     3121 acgtggaacg tgtctcaaaa cgcctgagga tctgcaaact agatgctacg gtcatggaag
     3181 tagaagaaac actgatgcgg aaagtaccac aagaattatg ggtaaagaca catcatacac
     3241 tgattttttt tggtagatat cattgcacgg caagaaatcc caagtgcgag gtatgtcctt
     3301 tgctatcaat atgtcaagat gggaaaaatc ggatgcgtct aaaagaaaag gcgctaaaaa
     3361 agaaaccacg cctgtagacg tggtttcttt aattgcaaat aaatgtatga attatcttgt
     3421 tattatggag aaaagctgtt tcgtttatct tttttgcatg aaaaagtaaa tgtacatact
     3481 cagtagctag gatggtaact tattacaatt tattgcgata aaaataaaag ttgttatttt
     3541 tattgggaaa atacccgatg tagaaaataa tgccttccaa tatacctata aaataagtcc
     3601 agtattccaa aggattatat aaataagtga cgtatctatc taaaggtgta ataaaaatga
     3661 taagtgataa taaaaaaata ccatttataa ctaaacataa actaatggat ttgggcggtt
     3721 tcaggctcat cagaaaaata tagattctgg tgaacaacaa ccataaaaaa gtgagaatca
     3781 ttgcatgaga gcttctttcc ataaattttc ctttaagagt agtgcttaaa agtacagaaa
     3841 aaataataaa tgcaaggata ggagcaatta aagtaaattt atttaataat aaacaaaatt
     3901 tttcagcttt tttattcttg gaataacgag gtattgtttt cgataaaaaa agatggtgca
     3961 gacaaattat gataattaag catactatca gataactcaa aatgaagcct tctttcaaaa
     4021 aattattcaa aaccatatat tgtatttttt atttgataat aacaatggga ttattaagaa
     4081 gtggcactaa ataaaagact agtgtgtatt tagccgattt aattataaac aagtaaatgg
     4141 ataaagtata tgtaatgata aaagaaaaat ggattttcta atttttaagc taaatgttag
     4201 atcacacatg tatatgctgg atagtcttat aaaaaatcat gtaatacagc ttggtacatg
     4261 atttttattt gtagctgttt tttacataga cacaaaaaag aaaccacgct tgtagacgtg
     4321 gtttcttttt tactatctgt ttccagaagc tgaggtgctg ctggatggtg tatggtcatt
     4381 tgcagcatcc gctccgctag ttgctggctc actggaagaa gcaggaggag cagatgaaga
     4441 cggtgtcgag ctttcttcgg atgaagaaga aggaaccgtt gttgaagacg ctggctcgct
     4501 tgtttctgct gtcgtgcttt cttttgagga ctcagcagtt gattcgcttt gactagtaga
     4561 gctagagctt tgagtcgttg tctctgttgt tgagcttcca ggagtctgga catagctgga
     4621 agatggaata gttgttgatg gtgtaattgc attcgatcta gctgtatatt gatctttgta
     4681 gtacagttca ccgcccacac gaattaatcc gcttggcatc tcccagtctg tatttgtcac
     4741 gttagctgaa acatactgca taagctcgcg ataaacatca gaggctacgt gtgacgattc
     4801 tgaagtgaca ggcgtcattt ttttattgta acctgtccac acggaaatcg aataatttgg
     4861 cgtatagccc gcaaatagga tatctggata caccccagaa gaaataccaa gttttgcata
     4921 ctcgtcatct gtgtaattgg atgttccggt cttaccggct tgatataacc cagcgatttg
     4981 cgcattcgta ccagttcctt cagtgatcgt atcttttaaa atgtctgtga tcatataagc
     5041 tgtttctgga gacatggctg tttttccatc tggctcataa gtttcttctg ttccgtcttg
     5101 gaagacgatt ttattaacat attgaggttt gtaataagtc cctccattgg cgaaagccgc
     5161 ataggctgct gccattttta aggaagaagc tccgtatttt gtcccatctt gttcttccgt
     5221 attactagag atcgcattcg attgatggat cgtactgtat tcgatcccaa gattttttaa
     5281 gaaagaagcc actttatctg aaccgacttc attgaataat ttgactgctg gaacattacg
     5341 ggataagtaa agtgcttggc gtaaagtaat ggtgcccata tattgattat cccagtttcc
     5401 tacaggagtc gaagtccctt catagttata cggtgcgtca gtaatagttt ttccagtaga
     5461 atatttcaaa tattcaaaag ctggtccgta atctgtgaca ggtttcatcg tagaaccaaa
     5521 atcacgggaa gtattcactg ctaagttgtt gcctaaagtt acgtcttctg cgatgtgacg
     5581 tccgccaatc tgggctttta ctttcccggt attggtgtcg ataagggtgg aggcaacttg
     5641 catctcgtcg tctgggtaag agacatactg atccgtgttg acgatatcat atagtttctt
     5701 ttgggcgtcc agatccaaat tcgtataaat ctctaaaccg tctgtgtaga cattcttatc
     5761 tgttttttct tgtacttcat tgatgacttc tttgacataa ttatcgacga tcttagtatt
     5821 gtcatcggat tgagttagtt cttgcagacc atccgttacc ggtacattaa cagcttgatc
     5881 atattctgtt tgagagattt tttcgttttg aagcatcgta tacaaaacag tatctcgtct
     5941 tttcttcgcc tgatctggat aaacataagg atcataggcg gaaggggctt gaggcatccc
     6001 agcaagcaat gctgtttgcg gtaaagaaag ttctgataat ttcttaccaa agtacatctc
     6061 agaagctgtc tccatcccgt acaagccgtt tgacatatac actttattta cgtagtaggt
     6121 caagatctct tgtttcgatt ttttttgttc caatcttaca gccatccacg cttcttgggc
     6181 cttgcgtttc agagtctgat cctcggcact ggtggagaag aaggaaagtt tgatcaattg
     6241 ctgtgtcaaa gtacttccgc cttgcagtcc gccagaggta aagttagaga gggcagaacc
     6301 gatgatccga atagggtcaa ccccgatgtg tttataaaaa cggcgatctt ctaccgacac
     6361 gatcgcatct tctaatgttt tcggtaattc attcgcagaa attttttcac gcttttctgc
     6421 gcctaaatct tcgaatagtt cgccatcttg tgtatatagt ttggaagata cggtagcgtc
     6481 taatttttta tccgtcaatt cgggcgcatc ttttgcgtaa taccagaaaa gtcctacacc
     6541 tgctaaaaag aggatacaga aaaatgagag tattcctaaa aggatcttga taaataatcc
     6601 ttttttatgt gttccagagg actttccaga acctttgcca gaattcttct tcacactctt
     6661 tttaggagta ggctgtttct gtcgtctaga gcttctagtt tgttcatttg ccattcttgc
     6721 tttctccttc aatagataat gttgataaat agaagtcaac cgcgtccaaa taaggaatcc
     6781 gcggagaaat accagttttg atctctattc ctagttcttc gatcaaagat aaaggtagtg
     6841 atttgcgtcc tttttccttt tgggcgtccc agtaagcaat caaatgaaca ctattcaaat
     6901 aaaaacagcg cttcaaagac gaaaaccata acaagacaaa gcagacccca ttttgttcga
     6961 ggcatgcttt catatgttcg atttgatggg catggaagtt tttaaaggga aaagatgttt
     7021 tgttcttggt ttcttttgct tcaaagtcca agtaaaagcc tcgatagacg ccattatagt
     7081 ctgtagttga ggcttgggta aagtaggctt ccttgatcac agcagcactt ctcttaggat
     7141 agtctacttt cacgatttgg ataggggtag gctttttatg gataaccgcc aacccgcggg
     7201 aaagataata tttattactt tcattgattg cttcttcaaa gcgcatcccc cgattgccga
     7261 attcagtgat ctgatttctt ttttcttgaa ttttttcgac gggagaggca ttcttataat
     7321 aaggttggcc atttggatag cgcaatacca tctttaatca cactcctagg ccacattata
     7381 gcaaaaaagc ggatagaaag aaaaggaatc tgagatggat aagtcaaaag taatctatgt
     7441 gtctgggtat cgaagtttcg aactcggtgt ttttaaagaa aatgatccta aaatccaagt
     7501 tgttaaaaat gttttaaaaa aagaactcca tcagttagca gaagaagggc tggaatgggt
     7561 acttgtcagt gggaatttgg gcgtcgaact atgggctgtg caaatagtag cggaattgaa
     7621 agaagaatat ccggaactat ctcttggtat tttgtatcct ttttctgatt ttggtaataa
     7681 ctggaatgaa gggaaccaag aaaaaaaaca attagcagaa caattagcag attatgtcga
     7741 agctgttagc catcaaccct accaatcacc tagtcagcta aagaatcaca ctcgttttat
     7801 acttgagcat acagtgggct gtctgctgat ctatgatgaa gaattccctg gaaaaacgaa
     7861 gtattttttt gaagatgcac agaattacca agcagatcat ccctacgaaa ttcggctgat
     7921 cagtatggac gatcttcaaa attttagtga ataatcgata ttgtgtttga tttatcaact
     7981 tttttcctat acaatgaaaa aggtagaaat gttattacgt aaatgaaaac tagaggtgta
     8041 aatatggcga atttggttta tagtcctaaa gacattttac aacaagaatt caaaacaaaa
     8101 atgcgcggct atgatcccgt tgaagttgat gaattcttag acaatatcat caaagattat
     8161 gaaacttaca gcaaagaact ccttgcttta caagaagaaa acgatcgatt gagtgcaaaa
     8221 gtagctcaat tatctaaaac tcaaggagca gctcaaacac gcgtgcaaca aacagaggca
     8281 ccaaagagcg cagcagtgac caattttgat atcttaaaac gcttgtcaaa tcttgaacgt
     8341 gaagtatttg gtaaaaagct tgatcaacaa gcaagtgcag tcaaaccagc acaacctaat
     8401 ccaaataact acacaaatgc agacacaagc ttagatgata atgaaaaaac acgtcaattt
     8461 taatttttga ttaatgaatt tgcggttttc gggtaatcgc ggtctgactt gatcaggctg
     8521 aggaaagtcc atgctcgcac aggctgtgat gcctgtagtg ttcgtgctta gcgaaaccat
     8581 aagctaaggt actctttgga gtaacggcag gaaaacaagc taaggcttcg gctatgctta
     8641 agtatccttg aaagtgccac agtgacgaag cggctgggga aacccatccg gtggaacgcg
     8701 gtaaacccct cgagcgagca acccaaacaa tggtaggggc gctttttgtc tggaagaaga
     8761 acaggacaaa aaggcagtat aactgcagat agatggttac cgctttgttt tttctccctg
     8821 gaaaagcaaa gtacagaaca tggcttatag aaaaccgcaa acatcaggga attaggtcgt
     8881 gacaaaagta atgcgttata agaaacaaga aaaacatttg aaagctattt ttcaatactt
     8941 cagatgaatc gttcttatta caaaacaaac ttttgtatca ccggttattc ggaatttgag
     9001 taaaagtgtg gggtaggact gatgtcccac ctcctttttt tataaataag gagattgtgt
     9061 atggaaaaaa acaggaagtt caacctcgtc gcaactgcgg caagcgggct agaagcactg
     9121 gttggtaaag aattaagaga tcttggaatc gaatgccaag ttgagaacgg acgtgcacgt
     9181 tttgaaggaa caatggaaac gatcgctaca gctaatttat ggttacgtac agcagatcga
     9241 gtaaaaatcg tggttgggga attcgatgcg tatacgtttg atgaattgtt tgaaaacgta
     9301 aaagcattgc cttgggaaga ttttcttcca ctagatgcag cttttcctgt agctggaaaa
     9361 tcgatcaagt cgaaactata tagcacacct gattgccaag cgatcacaaa aaaagcaatc
     9421 gttgaacgtc tccgtaccta ttatcaccgt ccagcttctg taccactgac ggaaactggc
     9481 gcacattttc agttggaagt agctttgctg aaagaccatg tgatggtaac tctggatacg
     9541 acaggaccaa gtttattcaa acgtggttat cgcttagaaa aaggtggagc accattgaaa
     9601 gaaaacatgg cagcagcact tattatgttg acaaattggc gaaaagaccg tccattttat
     9661 gatcctgtat gtggttcagg tacgctttgt attgaagcag ccttaatagg ccataatatc
     9721 gcaccaggat tcaatcgtga gtttgcttgc gaatcttggg attggttcag tcaagaaatc
     9781 atggaaaatg ttcgatcagc agccgaagaa aaagcagatt atgatattga attagatatt
     9841 actggttcag atatcaatgg acggatgatt gaaattgcca aagccaatgc agaagaaatc
     9901 ggattaggct cttcgattac ctttaagcaa caagcagtca aagacttcaa aacggataaa
     9961 gaatacgggg tcatcgtggc taatccgcct tacggagaac gtctaggaga agaagaaact
    10021 gttcggaaat tatataaaga aatgggcgat gtattccgtc cattaaaaac atggagtaaa
    10081 tatatcttga ctagcgactt agcgtttgag gaattttacg gacaaaaagc aaccaaaaaa
    10141 agaaaattgt acaatggtgc attgcgtacg gatctattcc agtattgggg aactcgtccg
    10201 cctagaaaaa aagagaaaga cgaataatct tactaattga ttcattcaat tggatgtttg
    10261 gaggaatagg gaatgaaaga aaaagagttt ttacaagaag taaaagaaat caatcttcta
    10321 caacaagctt taggaatcct cgattgggat acacaaacag gtatgcctga aaaagctagt
    10381 gcataccgaa gtgaagtaga cagctatctt tacagcattt atttttcaaa aaaaatcggt
    10441 ccaaaaatca aagaagccat tcgctatttt tctgaacatc cggaagaatt gtcggaagtt
    10501 ggaactgccg tttttgccaa agtaaaagaa gagtatgatt tggaacatcg cgtaccggaa
    10561 gatcttatga gaaaatatac agctgccgtt tcttcagcac acggacaatg gcaaaaagct
    10621 agagaaacac aacaattttc tgattttcaa cacgcattga atcaaaatat tgaattaaca
    10681 aaacagttga taccttactg gagaaaagat gaaaagacga attatgatgt tttgctgaat
    10741 caatacgaac ccgggatgac tgtcgaaatc cttgataagg tatttgatca gcttaaagaa
    10801 ggaattcttt cgatccgccg tacgctccaa gaaaaaggga ctgaacctga aacagacttt
    10861 ttaaatcgga gaatgacgaa aaaacaacag aagagatttg tagtgaaagt aatcgaacaa
    10921 cttggttatg attttagtcg tggtcgttta gatgacactg tccacccatt tatgactgga
    10981 attaatccga atgatgcacg aatcacgaca cgatggaacg aaacagattt caaaatggct
    11041 gtttttggag tgatccacga ggctggtcat ggtatgtatg aacaagacat cgatgataaa
    11101 tatgcgtata caccggttta tgaaggtaca tcaatgggta tccatgaatc acaatcgttg
    11161 tttaacgaga tcattattgg aagtagtcgc agcttctgga aaaagcaata tcctttcttt
    11221 caagaatgtg cagaaggaac attcgatgat attccttttg acaaatttta tcgttcattg
    11281 aaccatacaa aatcaagttt ggttcgtatc gaggcagaca gtttgactta ccctctccat
    11341 atcatcattc gttatgaaat cgaaaaaatg attttcaatg aaggggtaga tgttgctgaa
    11401 ctacctgaaa tatggaatca aaaatatgaa gagtatctgg gaatacgacc aacaaatgat
    11461 gtggaaggca tcctacaaga cgttcattgg tcaggtgcaa gctttggtta ttttccctct
    11521 tatgcattag ggtacatgta tgcggcacaa ttacttcatt ctttgcagca agaaatagat
    11581 gtggaaaatg ttctagcgtc agacgattat tctccaatca aaaactggat gtcagagcat
    11641 atccatcaat atggtgcatc tagaaaacca aatcaattaa tcatggatgc aacacatgaa
    11701 ccgcttaatc cgcaatacct gatcgactat atgaaagacc tgtattttaa tgtatatcag
    11761 gtaaaataaa atacaattta caaagatagc tgaaattcat ctaatctata gatgttttca
    11821 gctatttact taagaaagaa gtggaacgaa tggataaatt acaagtgatc gctgattata
    11881 gtatggacca attagcgcat gatcaaacag gacatgggag cgatcatacc aaaagagttg
    11941 tcaagttagc tgaaaaaatt ttggagacgg aaccgcaggc agaccgcttt gtgacgcttg
    12001 cagcagctta cctacatgat acgattgatg ataaagtcgt taaaaatgag aacgaggcaa
    12061 agcaacagct tcgtgtattc cttcgctctt tgccaatagt agaggaacag atctcgatga
    12121 ttttttccat tatcgaaaat atgtcctttt ctaaaaatct ctctgaagcg gccgaactat
    12181 ctctggaagg taagatcgtt caagacgctg atcgtatcga agcattagga gcaatcggca
    12241 ttttgcgtac tgcttatttc ggcggtggac atgggcaccc gatttttgat cctgaactgt
    12301 atccgcaaac attcaaggac aaagaaaatt accgaaaagg cacgacagtg atcaatcatt
    12361 tttatgaaaa actgttcttg ctgtctgata aaatgaatac tgattacgga tatgaagaag
    12421 ccaaacgaag agaaaccttc atgcgtgaat tcttagaaga attttttctg gaatggtcta
    12481 ttgacgatga aaattttact ccagacaatt ggatcaaaaa taacaaaaaa tgatggaggt
    12541 tgtgacagaa gtggtcagct ccaagatatt tcggatcatt ttccgtaaaa gttacttctg
    12601 gaacactgtt taccaagagg tcgtgagcct gccgttcagc tccgagtcac aaggaacaat
    12661 ttcaaaaaat agcttctcgt gtttgatgaa tattgtaact tgtgattcgg aattggcagg
    12721 agaacaccgt ttatt
//
LOCUS       DAIGSZ010000075        12495 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.076, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000075 DAIGSZ010000000
VERSION     DAIGSZ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.076"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            158..730
                     /locus_tag="NOB31_002381"
     CDS             158..730
                     /locus_tag="NOB31_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HCI0974561.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            875..1579
                     /locus_tag="NOB31_002382"
     CDS             875..1579
                     /locus_tag="NOB31_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCI0974562.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNSDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            1807..2145
                     /locus_tag="NOB31_002383"
     CDS             1807..2145
                     /locus_tag="NOB31_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974563.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2130..2984
                     /locus_tag="NOB31_002384"
     CDS             2130..2984
                     /locus_tag="NOB31_002384"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HCI0974564.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3131..3364
                     /locus_tag="NOB31_002385"
     CDS             3131..3364
                     /locus_tag="NOB31_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HCI0974565.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3562..5466
                     /locus_tag="NOB31_002386"
     CDS             3562..5466
                     /locus_tag="NOB31_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI0974566.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISIGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            5776..6138
                     /locus_tag="NOB31_002387"
     CDS             5776..6138
                     /locus_tag="NOB31_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0974567.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            6155..6766
                     /locus_tag="NOB31_002388"
     CDS             6155..6766
                     /locus_tag="NOB31_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HCI0974568.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(6868..7776)
                     /locus_tag="NOB31_002389"
     CDS             complement(6868..7776)
                     /locus_tag="NOB31_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCI0974569.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(7818..8132)
                     /locus_tag="NOB31_002390"
     CDS             complement(7818..8132)
                     /locus_tag="NOB31_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCI0974570.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            8431..10362
                     /locus_tag="NOB31_002391"
     CDS             8431..10362
                     /locus_tag="NOB31_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCI0974571.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTAMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            10655..11206
                     /locus_tag="NOB31_002392"
     CDS             10655..11206
                     /locus_tag="NOB31_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0974572.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            11519..12061
                     /locus_tag="NOB31_002393"
     CDS             11519..12061
                     /locus_tag="NOB31_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974573.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         4048 a         2092 c         2610 g         3745 t
ORIGIN      
        1 aatttaatag agaagcctgg cgtctattaa gaaataattt tcttgatgag cgtcaatttt
       61 tttaacggaa atctatccta tactaaattc agtaaagaaa aaggaggaat caaagaaagc
      121 tattttaaac aaaccaaaat tataggagga ataaatcatg actgaaaata aagctactca
      181 agaaagaaca ccccaagaaa gattgcaaga agaacaagaa cacaaggaac atgttcatca
      241 tacgaaaatt aatgcagcgg ccattgcgga tcatctttta ggcaacatgc atacattaca
      301 tgtgaaactg caccaatatc actggtatgt aaaaggagcc aatttcttta cgttgcatga
      361 aaaatttgaa gagttgtata acgaaaatga aaaatggttc gacaaacttg cggagcgtct
      421 aattacttct gggcataaac ctgcttcgac aacggttgaa tttgaaaaat attcgatgct
      481 ttcggaagat gcagttaata aatacgctaa agcagaagac atggttgaaa atattatcga
      541 ggacttcaga agcactcgtg acctaactat tcgcgcgatt cgtttagctc aagacgaggg
      601 tgacgatgct ttagaagata cattgattgc ttttaaaaat gacttagaca agaacatttg
      661 gatgctgcaa gcgttcattg gtaaagaagc attagaagat gatgacgctc ttgatgagga
      721 tgaagattaa ggtaaaagta gaagctgatt tagggattgg aattctttcc agtccttttt
      781 ccattttctt gatgtgcatc aatttttttg tagtaagaga cttatataat aaaagcagcg
      841 aatataaaca aaataaataa agggggagaa tgaattgact aaacataccc atcatgaaat
      901 tggcgaccac gcagcctgta tccgcttggt tccaatattc aatcacttag aggatagcgc
      961 gatgaattac attgctgaaa aagcccacac gaaacagtat caaaaaggag agtttctgtt
     1021 tcgttcacaa gaaaaagagg atactttata tattatcaat cgtgggaaaa tccgtattta
     1081 tcgattggca gactctggca aagagcagct agtgcggatc ttgaaccctg gtgatttcac
     1141 cggagaatgg accttgttca actcggatgc agtacacgag gaatatgccg aagcaacccg
     1201 agataccgtt gtctgtatga ttcagcaaaa agatgtccaa gattttctgg aacaataccc
     1261 agctatttct ttaaaactat tggcggaaat gtctaaacgg ttagaaagtt cagaacgtca
     1321 aacgacacaa gtagccgtgg agagtgtcat tacccgttta gttttgtttt tggcagaaaa
     1381 tgtggaacct gaaatgggca actctcccac catcaccctg ccgatggcaa aaaaggacat
     1441 tgcttcctat ttaggaacga cacctgagac catcagtcgc aaatttggag aattggagga
     1501 cgaaggattg attcaacagc tgtctgggaa aaggatcaag attcaggatt tagatgattt
     1561 attgctttac agcgaataat cggacacact tttttctaca cgttggtgtt ctgtcgctct
     1621 tcattaacaa cgggacagaa ctcagtgctt ttgcttccat ctgtccgttt ttggcttttt
     1681 taagacagaa cgaccttcat tcattggaaa aataaaagca caaacatgat aaccctcaag
     1741 tttttttgtt ttatttttct ttaagatagg gttgtcgaac aaaacgtaaa aataagtagg
     1801 gtgaatgtgc attgtttttg ggtgatagtt gccatcacgt tgtcagcagc gggggcattc
     1861 tttgtcgtcc ctttcaccaa gaacacgatt ggcggcgaag caaaaacgtc taacgttgtt
     1921 gaggcagata ggttagctat ggaaaaagaa gaggaagttg taaaaggagc cggcgtaatc
     1981 ggacacggaa aagtggcgta ttacgaagcg agtgaccagg gagataaaag tgtattcact
     2041 gtttggtttc catggagctt agccggaatc ttgttcagca tcaccatgac tagaatgacg
     2101 cgaaaaattg aagaaatgga gcaaatagaa tgggattcgt attaggcgtt ttgaatcccc
     2161 atgtggtgga gattggttct gttgtgattc attggtatgg agtcattatt gcagcgggca
     2221 tattagcggc tctccagttg agcaccaagg aagcaaagaa aaaaggactg gaagaggata
     2281 ccattatcga tatggcctta tgggcaattc cgattggact cctcggcgct cggctttatt
     2341 atgtgttatt tgaacttggt tattatctgc aaaatccagg acaaatcctt gcgatttgga
     2401 atggcggcat tgcgatttat gggggattga ttgcaggagg gggtacgcta tattggtatg
     2461 caaagaaaaa aggtacttct ttggcactcg ttcttgatat tttagcgccc aatgtattgt
     2521 tagcccagtc cattggtcgt tggggcaatt ttatgaatca ggaagctcat ggtgggccgg
     2581 ttactcgtca attcttggaa aatctttatt tacctgaatt tatcattgaa caaatgaata
     2641 tgaatggtac ctactaccat ccgacttttt tatacgagtc attgtggagt ttgttgggct
     2701 ttgtcctcat cgtcactata cggaaccgaa aacagctttt gcgtcaagga gaagtcgctt
     2761 tgagttacgt tttgtggtac tcagtgggtc ggttcttcat tgaaggtatg cgaacggaca
     2821 gtttatggat tggcgagtgg atccgcgttt cgcaagcctt gtctctggcc ctgtttattg
     2881 gcgcgattgt agtatggttt atacgcagac aagattatcc accaatttct tattattctg
     2941 atggcaataa ggggcagaaa aagactatta agatggtgaa ttgagcaaaa agataaaaag
     3001 aagtgcaaaa cttgatatgc gtcaattttc gtttgctaaa agtgagctat actacagttg
     3061 taaagaggaa aaggcagtgt tcattaatct gctgccgata aaataaaaac acataaagga
     3121 gataggaatt atggaaaaag ctatattgca attagaaacg ttgtcttgtc caagttgtat
     3181 gcaaaaaatt gaaggtgccg tgaaatcagt taacggtatt gataaagaca gcattaaagt
     3241 attattcaac tccagcaaag tcaaaaccaa ttttgattca gctgtcactt cgattgaaga
     3301 gattcaaaaa gctatcgaaa acgtaggcta tccggttctt aaagcaaaag tcaaggccgt
     3361 ttaacagatt aaatgaacta ggcaattctg gaagaaaagc tatttttcca ggattgcttt
     3421 ttttgttgca atccgattcg aggtgcttag aaacgataaa agagaacttt ctaaacttga
     3481 tgtcagtcaa ttaattactt aggcaattat cttatactgt gtttatcaat aaaagagaaa
     3541 ttaaatttgg agggaaaaag catgcaacaa tatatattaa gcaagaaaaa tgttatcacc
     3601 gtcatcagtg gattgttaat cgtactcggt ttcttcagtc actttgtttt agaaaacgta
     3661 ggactttcag agtggtcttt gatcatcgcc tctgtctttg ggattacgcc aattgccatt
     3721 caagcgtttc aagcaatgaa agtcaaagtc atcagtattg atgtcttagt cagtattgca
     3781 gcgattggtg cgctttttat tcaaaattat gaagaatcgg ctattgtcac gttcttattc
     3841 ttattcggac actacttgga acaacgaaca ttgaaccaaa cgcgatctgc tatcaaagaa
     3901 ttgactgaaa tggcacccga aagcgccttg aaacaaatgg ataatggcga atttgaagaa
     3961 gtagaagtgg atgatataga tgaaggggat atcttgctcg ttaaaacggg tgcgaaagtt
     4021 ccagtagatg gcatagtcct tacgggtgaa gggcatatca atgaagctag cattacaggt
     4081 gaagctattc cggtcaacaa gctagctgat gcagaagttt ttgcaggaac cattttagaa
     4141 aacggaacga ttcaaatcag agctgaccga gttggtgagg acaccacatt tggaaaaatt
     4201 attgaactcg tggaagaagc acaagattct aaatccgaag cggaacggtt cattgatcgc
     4261 ttttctaaat actacacacc agctgtcttg gttctggcaa ttgttgtatg ggcgttcagt
     4321 caaaatattg agttagcaat caccatcttg gttctaggtt gcccaggcgc attagttatc
     4381 ggagtgcctg tctcaaacgt tgccggtatt gggaatggtg ctcgtaacgg tgttctttta
     4441 aaagggagtg aagtcattca agacttcagt aatgtggata caattgtatt tgataagaca
     4501 ggtactttaa ctgtcggaaa cccaaccgtt gcagcgactg aactgtatga aaaagatcct
     4561 gctgaaacgc ttggctatct ggccagtgtg gaacgggaat cagatcatcc attagcaaaa
     4621 gcggtcttaa atcaaattgg agaaacaaac ttttatcctg ttgaaggaac tgaagttgtg
     4681 aaaggcggcg gaatcgtttc aagtgtagct ggacatagag tggctgttgg gaatgtggcc
     4741 ttgatggaaa aagaaaatgt cactctcagc aaaaaagtgc aaaaagatgt caaacggttt
     4801 gaacaacaag ggaactctct cgttttgaca gcggtcgacg gtgaattaaa agtactgatg
     4861 ggcattcgcg atcaagtccg tccgggtgtg aaagctaatt tgcaggaatt aaaagacttg
     4921 ggcgtgaaaa atctagtcgt tctttcagga gataaccaag gaaccgttga tgtggtcgcc
     4981 ggcgaacttg gtttgaccga agctcacggc tacatgttgc cggaagacaa atcggcttat
     5041 atcggaaaac ttcaacaacg tggtcaaatt gtagcctttg ttggagatgg cgttaacgat
     5101 agtccgtcct tagctttagc agacattgga atcgcaatgg gaagcggaac ggacgtagcg
     5161 attgaaacat ccgatgtcgt tttaatgaac tcgaacttca gcaacttgcc tcacgcatta
     5221 ggattagtaa aagccaccgc aaataatatg aaacaaaata tcgtgatttc aattggagta
     5281 gtgttggtct tgttgaccag cgtcttcttc agcgaatgga tgaatatgtc tatcggaatg
     5341 ttggttcatg aaggtagtat cttggtggta attttcaatg gcatgagatt aatgaagtat
     5401 aagttgaaag gtcgaaaaga acaaaaagaa gtatcagcac ctgcagagaa agtaaaaata
     5461 tcttaagaat aaattagaag aggctgagac aatagtccat ccttgaaatg acaaaagcgg
     5521 aaactcagat ttttaaatct gggattttcc gcttttttga gttcttgaaa aaaaataaga
     5581 gtatagagta tgttctttat aaaattaatt ttcgtgtaaa tgattaaaaa atttaataat
     5641 aaaatttaaa ttcctattaa gttgtaacac atgaaattgc ttataatagt gtattgaaat
     5701 taaggtagat tgacaaacga gtgatcaaat agatatacta ccttcaaacg accgtttgaa
     5761 tgtgaggtga gatgaatgga aaaagtttgc caagtgacta tcgtacataa agaaaaagta
     5821 aatgtaataa aaaaaaaatt ggatcaaaaa gatttttcaa acttacttgt gttagggaaa
     5881 tgtttcagcg attcttctag gattaaaatt ttctatgctt tagaaaccta taaggaaatg
     5941 tgtgtctgtg atttagcaga aatacttact gctagtgtcg ctacaacgtc acaccattta
     6001 cgttttttaa aaaaacatgg aatggcaaaa tcacgtcaag atggaaaagt agtttattat
     6061 tctttagcga atgaagacat cctttccgct attcgtgttt ttttaaagtt atcagaaaat
     6121 ctatctatga aatcttagtt tggaggaagt tattttgtta caaagtattt tttcagctat
     6181 cgctgtttat atttctacca gtattgatta tttgtttatc ttgctgatta tcttttctca
     6241 aagccacaca aaaaaaggta ttcgtcacat tttttggggt caatatcttg gaacaggtat
     6301 tttggtagcc gtaagtttgt ttgctgctta tgtgctaaat tttattccgc aagattggat
     6361 cattggtctt ctcggtctaa ttccgatttt cttaggaatc agagtcgctt ttgttggcga
     6421 agaggaggaa gaagaagagg aagtcgttga aaaactcgaa tctagaggaa ctaatcgctt
     6481 attctggaca gttgccttaa taacgattgc ttctggaggc gataatttag gtatttatat
     6541 tccatacttt acctcgttag ctttttcaga aatcattatt gctttaatcg tattcgctat
     6601 ctctgttgcg gttctctgct atatcagtta caaattagcc aagatttctt ttgtttccga
     6661 aacgttagaa aaatacgaac gaatcattgt ccctataatg tttattgcgt taggaatttt
     6721 tattatgata gagaacggga cgatacaaac gctactaggt ttttaaaaat cataatcacg
     6781 aaagataaaa agagaggcag cgactaatca aaatcgctgc cttttttgct tttcaaataa
     6841 tgaagtattt tttagcgtag aactatctta cgtgttgtgg gagtatccct tttcaagctc
     6901 ttctttgctt gtagttattt ctattgtgat atgattctct acgcttgatt tgtgtgcgac
     6961 ttctgcaatt tcttctttta tttccctagc cttgtctatg tctgaagggt ctataagaac
     7021 cgtgatgata agggcgtttt cttccccgtc cagtgaccaa atgtgaaaat gtgagaggtc
     7081 ttttacagca ggaacatttt taatggagtc cgccaagctc tttacgttta cattttcagg
     7141 cgaaccattc aataaaattt tcattgtggt gaaaaattca ggaacggttt tgtagaggat
     7201 ataaagtgca atcaaaatcg ataagatagg atccagacga tatgcctcgg taaagttcat
     7261 tagaatactc acaatcaaga ctccaatcca ccctaatacg tcttccagca tatggaggtt
     7321 caacatgctc tcgtttttgg atgtgccttt gcttaaaatc cacgcagcat atccattcaa
     7381 tgcaatagct acgagagaaa gccagaacat gccactataa tttacgggtt gtgggtcaat
     7441 caaacgtggc acactacgat agatcataaa aaacgagcca ctaattagca caacgccagt
     7501 tatcagcgcg cccagtaaag aaaagcggtt atagccaaaa gtgaaccgtt catcttgttt
     7561 tttctctgaa taaccttgaa aaaaccaagc gaatccaatt gaaatagagt cccctaaatc
     7621 atgaactgcg tcggacataa tggacacact attgaaaaga aagccaaaga aaaattcgct
     7681 tatagagaaa ataagattta tgaagaaagc aattttaata ttctttttcg gttgattctg
     7741 attcgagtga ttatggtctt tatctgattt tgacatttaa aaacctccta agtttgtatg
     7801 ctacatacta attggtttta tttttctaat tcattaacat gagttaagac ttgttcgaga
     7861 atactaaaaa catgaaggtc atctaaactg taaagcatac tttttccttc tcttcttgat
     7921 ttcactaagc gtgcgtcttt caacgttttt aattgatgag aaatagcgga ctgttccatg
     7981 tccagagaaa tagcgatatt tccaacacta cactcttttt tctgtaaaag aaagagaacc
     8041 gacaatcgtg taggatcact aatcacctta aatagtttgc ttattgacag aatagatcct
     8101 ttatcgattg gagaagttgt ttttatatcc atagtgtttt tattcctttc atatgacctt
     8161 ccgttcatat ctatattacc atatgagcga aacaatgcta atcttttgtt tataaaagag
     8221 aagtggcgtt ctctttatct tgacaaaatg tatatagcga tataaaatga gtatacaaac
     8281 atatgattaa ttagtcatat gtaaggtgga ttcattacga tttacttttg gaataaacga
     8341 aaggagtcag aaatagcaga aatttatgtg attcaagaag taaatgatgg aaaacaaagg
     8401 aattataaat tatataggga ggcaatagaa gtggaaacta tccaagaaca acagtctcaa
     8461 gaaaagcata atcataatca caaccacgat cacgaccatg atcatgggaa aatgccagtc
     8521 gttttgtact ttgttggttt agcattagca gtgattgctc tatttttgaa tgaagattat
     8581 cagttggtac aaaatgtttt gttctcaatc gctacaatca gtgccgggta tcacgttatt
     8641 cttcttgaag gccttggaga aacaattgag aattcaaaag cacaaaaaaa gttcatacct
     8701 aattctcata ttttaatggg attagcggca attggagctt ctttgatggg gaatttttgg
     8761 gaaggaacat tattgattct tattttttct ggcgcacatt ttttggaaga ttatgcagaa
     8821 ggaagaagca aacgagaaat aacgaaatta ctcgaaatga atccaacgac tgcccggtta
     8881 atcctgcctg atggtagtac aaaaaatgtg gatgtcagtg aattaaaagt gggagatcaa
     8941 cttcaagtgt tgaatggcga tcaagtacct attgatggcg tcattttgtc tggatctaca
     9001 tccattgatg agtcgtctat tactggagaa agtatcccga aagagaaatc caaaggagat
     9061 ggcgtcttcg ggagtacaat caatggaaca ggtaccttca cgatgaaagt caccaaagaa
     9121 aacaaagata cagtattttc aaaaatttta caattagtga atcagaacca agataaccaa
     9181 acaaaagctg cgagtattat ccaaaaattt gaaccgaaat atgtcacagt tgttttaatt
     9241 gccattcctc tattcatgtt attggctcct tttctacttg attggacatg gtcacaaagt
     9301 gtctatagag gattggtcct tttagttgca gcttcaccgt gtgctttagc agcagctact
     9361 gtctcggcaa cgctatcgac gacttctaat ttagccaaaa aaggagtcct ttcaaaaggt
     9421 agttcttacc tgtctcaatt agccgatatt aaagcaattg catttgataa gacgggcacc
     9481 ttgaccaaag gaaaacctga agtaaccaat tattattttg ctgattccgt gaacgaagaa
     9541 aacatgattg atatcgtagt agctcttgaa aaagaatcca atcacccctt agcagatgct
     9601 attctaagaa agtttgagca aaaaaacaaa ctaactattg aagtagaaaa ccaaattggt
     9661 aaaggattga cgggagatta caaagggaga aattatcgta taggaaaacc gacttcgttt
     9721 gatgatgttt cagatgaata tagtcgttta aataatgaat gggcgtcaga aggtaagaca
     9781 gtcgtatacg tagcagtaga tgaagaggtt ataggcctta ttgcccttat ggacgttccg
     9841 agtgaatatg ctaaagaaac cattgaatat tttaggaaac aaggtataca caccacatta
     9901 attactggtg actcagaaat gacgggaaaa gcggttgcta aacaattagg aatagatgaa
     9961 gtgattgcga atgtcatgcc ggaagacaaa tccagaatta tagacgaaca aaaagaaaaa
    10021 tacggcgtga ccgccatggt tggagacggt gtaaatgatg ctcctgctct tgttaatgca
    10081 gatgtgggaa tcgctatggg agatgggact gatgtggcag tagaggtatc tgatttagtt
    10141 ttaatgcaaa acaatttatc taaattggta caatctcata atatttcttc gaaaatgaac
    10201 cgtgttattt ggcagaatat tattttttca atggccgttg ttgctttttt aattgtcgtt
    10261 agtttcttag gcttaacgga tattgcaatc agtgtcatta ttcatgaagg aagtactttg
    10321 gttgttattt tgaatggact tcgattgcta aaggcagtct aaagaatgat tgcacaactt
    10381 caaattaatc gagtaataga gataattaag gattacacta cattttttat ctctattact
    10441 tgtttatatt tatctagatg ttcaaagtca aaatgatata tcaaccatac tcttgtggcg
    10501 cgggttgaat ataagataca tgaaattgga taaaatcatg tatcaagaat cctatcctta
    10561 tagggttctt tttttttact ccccctaaac acacgatttc gtgttgtaat aactataatc
    10621 atgtattcga acagactaaa aaggagggat tgtcatgggc tataatgttc agccactacg
    10681 gtcgcaacag gagattaatg attttttatt ttgcctgcga cggaataaaa atgcggaacg
    10741 tgacgttttc ttgtttctaa ttggaattaa cagcggtctg cgcatgtccg acatcgttaa
    10801 actcaagaaa aaagacgtga ttacctcaaa aaacccgcgc atcgtggagc aaaagacagg
    10861 gaaaacacgc attttatact taagcagctt acaggacttg attcacggct ataccgcacc
    10921 cttagatccg gaggcttact tgtttcccag tactaagggc ggccatttag aagtcaatac
    10981 ggtctaccag atgtttcaaa aggtcgcgaa gctgttagga agggacgata tcggcaccca
    11041 caccctacga aaaacctttg gttaccacta ttacaagaaa accaaagacg tggccacctt
    11101 aatggaaatc tttggtcaca gcagcgagaa gattaccaaa cgctacatcg gaattaatga
    11161 agatgaaatc agtgaaacgt tattaaattt tcggttaggt ttttgattgt attatataat
    11221 agataagcac agtaagacgg ttataatcac ccacagtatt ggacaaatca accttttttt
    11281 ggtatattat atatacaaat gagagcaggc tcatagtcaa cttgatataa atccggaaca
    11341 taagggtccg gcgggtggcg agcaccaaaa ctaaactcga tacaaatccg gaacgtaagg
    11401 gtccggcggg tggcaagcac caaaactaaa cctgtacaaa aggctgctct tttgagcagc
    11461 tttttttatt gggaaaaagg agcattcttc gcacgcggca aaaaaagaat acaaacgcat
    11521 gtctataaaa gagacaaccc aaattaccag acagttaaac gcgatttata aggctgctca
    11581 tctcttacaa gaacattttg tagataaaaa agtatccttt gtcggagaag tctcaacggt
    11641 agcgattatt ttttcgacaa ctaattttat gcacctctgt ggcattgatt atcgcagagg
    11701 cacacacttg ttttttcaag atgccttaga caggaaaata aatttacagg atattcaaat
    11761 caaaacggat gggacgacct ttcagaaatt acaagtaata ggtagccttg atttattatt
    11821 ggggaagcat atttctattg ttggcagagg tgtttactct tctcttcgct atgatgcagc
    11881 tattcgaaca aggaaaaaaa tattggctct gtctttgaaa caaaacggat taatctatat
    11941 ccctatctct ttgttaaacc tatcatcaaa ggaaattgga cctggacaaa aagttactgg
    12001 catttttagc gaggatttaa catccgggga acttaaaatg attatggaag tcatcgatta
    12061 atcattaata gtgatatgcg acgtcatttt gaagtaatta ttctattttg ggttataaaa
    12121 taaagcattt taagacgatt tcaaatcatt catgtgggtt atttatcacg gatgagcttg
    12181 aaatcgtctt ttatacgtat caaattgaaa tgttcggcat acaacctatc gttgttacta
    12241 cattactaat tgtcacttgt taaggaactt ggatcctttc taaacattcc ctagagataa
    12301 attttacttt atccctccgt taatatccaa tttaagcacc tttccgattc agggttaatt
    12361 tgcatatcaa gtgcagcttg tgttctagta agattagccc ttttagtccg gctgagttga
    12421 cttatggata taagatatgg tcatagcaaa tagatactac gtatagtctg ttaatttagt
    12481 gtcattaatc ttaag
//
LOCUS       DAIGSZ010000076        12486 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.077, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000076 DAIGSZ010000000
VERSION     DAIGSZ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.077"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..190)
                     /locus_tag="NOB31_002394"
     CDS             complement(<1..190)
                     /locus_tag="NOB31_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974574.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(200..1015)
                     /locus_tag="NOB31_002395"
     CDS             complement(200..1015)
                     /locus_tag="NOB31_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCI0974575.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1277..1720)
                     /locus_tag="NOB31_002396"
     CDS             complement(1277..1720)
                     /locus_tag="NOB31_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HCI0974576.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1854..2192)
                     /locus_tag="NOB31_002397"
     CDS             complement(1854..2192)
                     /locus_tag="NOB31_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0974577.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2180..2557)
                     /locus_tag="NOB31_002398"
     CDS             complement(2180..2557)
                     /locus_tag="NOB31_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCI0974578.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2781..3974
                     /locus_tag="NOB31_002399"
     CDS             2781..3974
                     /locus_tag="NOB31_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0974579.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4140..4562)
                     /locus_tag="NOB31_002400"
     CDS             complement(4140..4562)
                     /locus_tag="NOB31_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0974580.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4957..5151
                     /locus_tag="NOB31_002401"
     CDS             4957..5151
                     /locus_tag="NOB31_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974581.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5148..5642
                     /locus_tag="NOB31_002402"
     CDS             5148..5642
                     /locus_tag="NOB31_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974582.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(5804..6976)
                     /locus_tag="NOB31_002403"
     CDS             complement(5804..6976)
                     /locus_tag="NOB31_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCI0974583.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7182..7997)
                     /locus_tag="NOB31_002404"
     CDS             complement(7182..7997)
                     /locus_tag="NOB31_002404"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCI0974584.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNMI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8147..8593)
                     /locus_tag="NOB31_002405"
     CDS             complement(8147..8593)
                     /locus_tag="NOB31_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HCI0974585.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8590..9594)
                     /locus_tag="NOB31_002406"
     CDS             complement(8590..9594)
                     /locus_tag="NOB31_002406"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCI0974586.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9634..9963)
                     /locus_tag="NOB31_002407"
     CDS             complement(9634..9963)
                     /locus_tag="NOB31_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HCI0974587.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10089..12416)
                     /locus_tag="NOB31_002408"
     CDS             complement(10089..12416)
                     /locus_tag="NOB31_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCI0974588.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         3534 a         2437 c         2273 g         4242 t
ORIGIN      
        1 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
       61 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
      121 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
      181 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
      241 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
      301 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
      361 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
      421 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
      481 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
      541 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
      601 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
      661 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
      721 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
      781 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
      841 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
      901 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
      961 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     1021 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     1081 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     1141 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     1201 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     1261 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     1321 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     1381 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     1441 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     1501 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     1561 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     1621 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     1681 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     1741 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     1801 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     1861 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     1921 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     1981 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     2041 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     2101 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     2161 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     2221 catatttctt gatttttcct tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt
     2281 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     2341 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     2401 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     2461 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     2521 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     2581 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     2641 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     2701 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     2761 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa ggtattatta tcgacatcgg
     2821 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     2881 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     2941 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     3001 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     3061 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     3121 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     3181 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     3241 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     3301 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     3361 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     3421 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     3481 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     3541 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     3601 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     3661 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     3721 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     3781 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     3841 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     3901 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     3961 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     4021 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     4081 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggcgac
     4141 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     4201 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     4261 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     4321 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     4381 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     4441 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     4501 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     4561 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     4621 atatcatatt gtcacaccgt caatagtgca taaacctgtt attatttctc tttttttcct
     4681 aagtattcta ttgatatgaa tcatttaatc gtttattata taaatgtcaa taatctaata
     4741 ataaaataac gtacatattt tattattgca tacttaataa cagaactata gcaaaaaatc
     4801 ccgtgtatca acacgggatt agattaagtt tcctcaatca ctattcataa cacaattatt
     4861 ataacaagta agtaaacaat tgaaaaggac atttattgaa aacggttgtt ttttacttaa
     4921 ggaggaaatt tagcgaaaaa attagttgca ttgtttttgg tcgcaggaag tttgttgagt
     4981 gggtgtggtg ctactacgtc tactactcaa agcacaagtt cagatcaggc ttccagcagc
     5041 agtaccacga tctccgaaag tacggcagat tcatcgaaag aacaagaaca aattgaaaag
     5101 aaaaaagaag agaaacaaaa agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg
     5161 aatctgcttt gtcacaagct gaagcaaatc ctacaaaaga aaactatgca actgcttcag
     5221 cagctatcca agcgctacct gaaaacaaac aagagttgac aagccgtctt gctgcaattg
     5281 attccacaat caaagcaaaa gaagcagaag aagaacggaa aaagcaagaa gaaattgcac
     5341 gacaacaagc agaacaagcg caacaagaag caatcgcaca gcaacaagca gaacaggcga
     5401 ggcaagaagc aatcgcacag caacaagcag aacaggcgcg acagcaatca gcagctgaac
     5461 aggcctctca gcaggcacaa gccgcagctc ctgagcaaaa taatgaacaa actgtctatg
     5521 tcacaccgac cggttcaaaa taccatacac ataaatgtgg aaatggtacg tatacccctg
     5581 ccactttaag cgaagctcaa gctcgtggtt taaccccttg ctccaaatgt tatggaaact
     5641 aattcaaaag ttatactata ataataaaat tcttctgaaa cataaaaaaa tagaagatgg
     5701 cgttccagat agtaaaccaa aaataacagt ttacacgtcc atttcgtcag cttctctctt
     5761 ttttcattta gtctgttccc tctgcttttt tggacatctt cattcattct ttctcaatca
     5821 aatagtacac ctctttttct tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa
     5881 actgtttcga atgtttatgt tttacatgga ttttaagcag gagctcctca tgttgcaagc
     5941 gatagttcct gccttttaaa tcagaaaatc tcactagtcc gtattcatca gaagctttca
     6001 caaatggaac tttttctcta gtaatatagt gtttgccgtt gagcgttttt acagaaaaga
     6061 ccattccttc gattggtcgt ccgtttgtgt tctttacata aaaagataaa ggatagtttc
     6121 gcttagcgat ggccaaagaa tctaaataag cgatgagtag ccaaactaag ccgattgatc
     6181 caagtagtat accgataaac caaataaaaa atttccattt tttccattga tcaattcctt
     6241 ggatcgcttt ttttgcctct tttgcttgat aaggaatacg atgccccgtc acaagcagtc
     6301 gatgtgtatt gaccatataa ggagtacagg taagcaaagt cacgagatct ctgccttttt
     6361 ggatacccaa agaatctact tcatcaggta agaccacttg gattttttct acttgatacg
     6421 ccaatgtctt tccattgatc tggatgaaaa actggtctcc ttttttcaac ttaggcaaat
     6481 ctgtaaataa ttttgcttct gggagtccac gatgcccaga aagaacggca tgggtgtttt
     6541 tcccgccagt cggataagaa ctttcttcca ataatgacgt tcctttttgc aaaaatattt
     6601 ccgttgtctg atcgaatata ggtaagctga cattgatttt tgggatttcg atgactccaa
     6661 gcatatgttc cataaaaaag gcattactag gtaaatcttt taatgctttt gcatcaactg
     6721 cttggttgaa actgcctatc cctggtgata cgttttgctc tgccaactgt tggtttttct
     6781 ttgtcatttt ttcctgctgt ttttttattt cctctgaatt cttattcgat gcttgctttt
     6841 gataatggat gatcatttgc tgggcaagaa aatcattcag tgaatcttct acaaaaggat
     6901 aagaaaagat cccgatccca acgactaaaa tgattgccat gaagatgtcc agtattctta
     6961 ttctgctttt attcatcatg tccacctatt ttctaatatg tatatgaaga ggttgtgaaa
     7021 tcagcgcctt gacctgagta ttagcgaagc aaacggcaaa atagttcctc ctattttgcc
     7081 gtttgttgag cgaataccaa gagaccgacc acttgtcaca acctttctcc ccatttgaat
     7141 cactatcgtt tatttatcgt atgatttttg tttccaatag tttaagcttc tgtttcttga
     7201 tggcgttttt tgaaatagat cactgctcct ccaactaaag cagtacctac caagatgaat
     7261 acgatgatcc ccataccacc agttgaaggc aagattcctt taggttggtt atcgatcgtt
     7321 gtttcatcag aagttgttgg atcatcatct actgtaaatt cagtgtacgc agcttcattc
     7381 ttaggtaatg cgtagccttc tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc
     7441 agcccttcga ttgaaaattt cccttctgaa tcagaaatca atttcacttc ttcccagtca
     7501 gaacctgtga cttcatctga ccaagcatat gggtattctc ctgaggcaag gtttgctatt
     7561 tttttcatta atttaacagt tggatctttt gctcttagaa tagaaaattc tgcatcggct
     7621 aatttttctt gcgtgttcac atcttgtttg atgaagtgga aatcaccgta gttttggaca
     7681 ttttctacag taatcatgtt atccgtagtt gtattttccc gattgactac accgtttgga
     7741 ttcccaagat tggcttcatc tgcgccatgg atgataccgg ttgtttgttg caattttccg
     7801 ttttttacta taaaagtagt ttctttttgt ggattggtta attgataacc atctggtgct
     7861 tttgtttcaa ctaaagtata attgccgtct attaatccat tgacactgat ggatccttca
     7921 gtatcagttg tgaatgtcaa cgctgactca gcaggatcat agagagcgac accagtgttt
     7981 tcatcaaaac cggtcacgaa ttgattctct gaatttttga tctggaattg cgcccctgct
     8041 aacttatcta cccctgaaaa gttcccagct ttctggattt tgatattgct ttctttgatg
     8101 acatttttag catataggtg aatcgtgtct aaaggtttgt cagggtctag ggtaagctta
     8161 acacgatatt tggcgacgtt tcgacaccgg gctttggtgt ttctacaaag acgtatacag
     8221 catctttccc atcagattta cctggaagag tcaggttagc taatccttca ccagaagtcg
     8281 ttacacttgc gaagggtgta gcgtctgctg gaactgctgt gtctttactt ggatagtacg
     8341 tagcagtgat gtcatatacg ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg
     8401 tcaattccgt tccgttgttt atttgatttt ctggtgctga agtgaatttc aatttatgca
     8461 aattaaccgt aacattttct ggtgtaggtg atacggctgc agaaacctct gcagttccta
     8521 ggccgagaac gaaaggaagc agcatgatag cagttcctaa aaacgtccat atttttgttt
     8581 tgatgttttt cattttattt ccctcctatt gtttcctttt tgttgttttt tataaaacca
     8641 agctgtccct gttgaaagga ctagcaataa ccctaaaatt gagaaacctc caagcatctc
     8701 ttcgcttgtt tttggaaagc ttcctccatt tttttcattt gatggaccat ttgtctgcat
     8761 ctgaactggc gtttttccat tattcgtcgg atttgctttt ggttcgttga tgatttccaa
     8821 tggtatagga tgaagcggat cataactgcc tttttcaact tcaaagagaa tggttgattg
     8881 actcaatata tatcctttag gcggtttaat ctccactagt tcgtaacttc caaaagacaa
     8941 tccatggaca gaaaatgttc catctttact ggaagtaaaa atcgttgctc ttgaatcatc
     9001 tttggctacc caatgattta tcccgttttc ttgcgctaag tattggtcat tttttttgac
     9061 tagaaattga gcatctgcta gtttttgttt cgtttgccga tccactttga caaattgttt
     9121 gcctcctgtt tggatggcaa gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac
     9181 atcgttatca aatgtcgttt tttcactgtt ttctttcaat gtcatttggt aacggatcgt
     9241 taattttttt ccagcaaacg aactaagatc ttttccagaa tctgataaga caaaaccatg
     9301 ttttattttt tgtgtgtgaa atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt
     9361 ttctggttct agccataact gaggatcagc tgtatctttg atcgtatagg ttcctatctc
     9421 gttgatgttc tcaggaattg ttacggtgat gagataaggg actttatccc catctgcaaa
     9481 atctgtctgc ttattctcta ctgtttttgt taatgtgagt gcagcaggta ttttttgttc
     9541 gctctttgga tacaagtgga tggtcgtcaa tttatgatta gatgaatctg tcacaggaag
     9601 cacaacgaca aatggtgctg atttttcttt tacttaatct gaagtcttta tttccgtaaa
     9661 tcggtaaaca gcgtcacgac cttgctcatc tttgtccgat gcactaaaag aagcaatgcc
     9721 ctcttcctcg tctactgttt ttgtcacatt ttctgccagt attttttcac tatcactttt
     9781 ttgtgctagt tttctttgtg cgtcttccac actacttcct tctgaccgca gcttgtaaaa
     9841 ttcatccgag acatcatata tagcgaaagt aacgccgttc aaccctttta ctccttgaaa
     9901 gttatccggg atatttattc cgtcgttttg actgatactt ggcatcttat cgctttcgaa
     9961 cattcgatta tgcaaagtaa atgtaatagg tgattctcta gctgacacag tcggagaacc
    10021 tataaaaaag accagtagga taaaaaagag aacagcaaat atatccacac gtacattttt
    10081 tgtttttttc atcgctgttc acctgctttt ttcttacgat ggataaaata aaagaagcca
    10141 gaaaaaataa agatcagtcc taaaaagaca aagggcagta gacctatccc acctgtcgaa
    10201 ggaagcaaga gagtcggatt gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa
    10261 ttattgttta cacttccttc gcctaaacta atcgttacta tttgtgatcc aatatctgtc
    10321 cggctgttaa ctgttagggt ataatccaat gattcgccta agacaacacc ggtaacgtgg
    10381 agatttccaa ccgaaatcga gtgactttgg gcatcataat taaaggcagc gtcatcgaca
    10441 gtaatcactg cgttagcttt atagatggta taagttcctg atgtgttggc tatatcagta
    10501 aatgacaact tgggatttgc tgctttgact ttgtctattc cgctattcgt tagtttaatt
    10561 gtatagctgc cagcattaac catatttttt gctgattgtg catctgctgt gtaatccata
    10621 ctgctaagtg ccacttgtac tggagtaagc gaactagtga caccctctgc tagcttgaca
    10681 tggattgacg ggacacctgc ttttccatca tatgtcttac tgccactgag ctctaccgca
    10741 ccgctgattt gcttaatcgt atagacatca gatgtctgca cgatagtaaa taaatagttt
    10801 gttctggcag ctagtttagc tagtccgctt tttgtcaatt gccaagacgt ataggttcca
    10861 atttcagtag gcgcagttac ttcaactccc ttttcattca tcgctttgaa atcagttgga
    10921 ttccatgtga tttgatcaat actgagatca ttgtttaaaa gggatgttga ttctgtttta
    10981 tcattaaagg catatttaac gatcggtaca acagaaagac catcatagta cttactgcca
    11041 tttgcattga ttgatactgt tgcatttgtc ttataatata ggatgacttc agaaatctgt
    11101 tttccatttg cgtcctttac gattacattt ccatttgtat ctaaactagc taaaacactc
    11161 attgctgatt ggttctttgt ttctatcgct gaaacagctg taaaggtata tccgttgata
    11221 gtaggcgtat tagtcgtcag gtcttgtgca gcacttccgt aagtaagatt cattatttta
    11281 gaaggagcaa tcatctgtcc aaaatagtct tgatacttaa tagtgattgg tgtttgtttg
    11341 cctgtatagg tcaccgtatc gacgttactt tctagggctg tgaaagaacc gtttgtttgt
    11401 gcaaaagaat agcccgttac tgctgttgga gtgataacca ctttgtcacc cacatggatt
    11461 ccagataatg tagtcccgta cgttccgatt tttgctgctc caccattgac tgtataagaa
    11521 aaagttcctg tccgattcgc attgacctga accgttgctg cttgataggt tggaaaattt
    11581 gaaacatttc ccttaccatc aacgatctgc ccatttttga tcgagtaccc cgtgaatgga
    11641 atatcatttg ctaactgtat accgattgaa aaagtactca tacctcctcc ggcaggaagc
    11701 cctccccatg ttgagggtgt aaaagaataa cttttatccg cattgggtgt aactgaatcg
    11761 atcgtatttc cagcggtagc cacccccata tagatacttt ttgggaatgt gatagtagta
    11821 ccatttactg tggagccaat aaacagatta tggatatctg gacggttatc aataaaagcg
    11881 attgctttgg ttacgccttg taacgcagtt ttatccgcac tcatcgatcc gttaaccgca
    11941 acaatgactc catctttggc atatatcact gtatatccat ctggtatggt atgtccgttg
    12001 aaattcgcag tggccgcaac agtactaaat gtctggcttc tacctgtttc tgaataagct
    12061 ttctcccctg ctgcttttgc tgctgtgatt tctttttctg tcggatcaat cagttgagtc
    12121 gaggatgtgg ttgaggttgt ctcgttgttg ctagactgat tggtgctttc tatggactgt
    12181 atttcagaat agggtggact atttgtctcc tctgtcgttt ggttagcaaa atttgacgtt
    12241 tctgtataaa cgtttacata aatacttgat aagctcccta agaaagtaaa aatcaagatg
    12301 atcgaaatca taatgggatg taagtatttt cttttagata cagctttgag tctagaaaca
    12361 aaatgttttt gacatatacg ttggatttta ttttgagttt tcttaatcat tttcatccct
    12421 cctctcaata aaaaatcatc aaataatcct ttacacgtta ttctaaattt aatttttatt
    12481 atttta
//
LOCUS       DAIGSZ010000077        11514 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.079, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000077 DAIGSZ010000000
VERSION     DAIGSZ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.079"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(79..2154)
                     /locus_tag="NOB31_002409"
     CDS             complement(79..2154)
                     /locus_tag="NOB31_002409"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HCI0974589.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDIKTDRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKDHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEV
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2156..3073)
                     /gene="glyQ"
                     /locus_tag="NOB31_002410"
     CDS             complement(2156..3073)
                     /gene="glyQ"
                     /locus_tag="NOB31_002410"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HCI0974590.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRF
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARSVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(3457..4269)
                     /gene="recO"
                     /locus_tag="NOB31_002411"
     CDS             complement(3457..4269)
                     /gene="recO"
                     /locus_tag="NOB31_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HCI0974591.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFLSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHAYPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKMPEKNMPEKEIPEKEE"
     gene            complement(4412..5311)
                     /gene="era"
                     /locus_tag="NOB31_002412"
     CDS             complement(4412..5311)
                     /gene="era"
                     /locus_tag="NOB31_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HCI0974592.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYTALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5326..5721)
                     /locus_tag="NOB31_002413"
     CDS             complement(5326..5721)
                     /locus_tag="NOB31_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HCI0974593.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQIDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5705..6181)
                     /gene="ybeY"
                     /locus_tag="NOB31_002414"
     CDS             complement(5705..6181)
                     /gene="ybeY"
                     /locus_tag="NOB31_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HCI0974594.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6198..8390)
                     /locus_tag="NOB31_002415"
     CDS             complement(6198..8390)
                     /locus_tag="NOB31_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HCI0974595.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNTGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8414..9385)
                     /locus_tag="NOB31_002416"
     CDS             complement(8414..9385)
                     /locus_tag="NOB31_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HCI0974596.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10090..11469
                     /gene="brnQ"
                     /locus_tag="NOB31_002417"
     CDS             10090..11469
                     /gene="brnQ"
                     /locus_tag="NOB31_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCI0974597.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         3111 a         2419 c         2104 g         3880 t
ORIGIN      
        1 ttatttatat ttataacaaa taaaccagag aaatagccta ttttgtgcct gttctctggt
       61 ttatttacat attagaaatt attttgtgat gatttgatct aaacttgcta gtgacaaagc
      121 catggcagca atttgactta attgcgttaa tcggttctta cgtactgctg gttcttctgc
      181 catgaccatc gtctgatcaa aataattttc gatcagtggg cgaaggctta caagctgatc
      241 ataattttcg ttgatcgttt ggtcagcaaa gcttgttttc attacctcta ctgctttgtg
      301 cagttctttc tccgcttcgt tttcgaacag ttcagggtct acttctgatt gtttttcaag
      361 ctccgctttt ttcgctaagt tcacgacacg tgtcaaagct tccatcgatg gtttgaagtc
      421 ttcatctgca agatgctgct tgaacaattg tgctgctgca aatacttttg tcagatcttt
      481 ttgttctgcg ttcaaaacag cttcgatgac atcatgacgg atattcttcg ttgtcaataa
      541 ttggcgcaga cggcctttga taaagtcgat cacctgttgt tgtcccgctg acaagccaat
      601 gccaaaacga tccgtatctt tactgataac ttcactaatc gtttcttgca gaacagacaa
      661 aggaaaggcc cattttttcg attcgatgat tcgaacgaca ccatatgctt gacggcgcaa
      721 agcatatgga tcgtttgagc cacttgggat catcccaact gcaaagaaag aaaagatact
      781 atctaattta tcagcaatcg ctaaaacaga acctactgta gtctcaggta aatctccttc
      841 actggatata ggcatgtaat gttcacggat cgctgttgct acggctggtt tctcgccttt
      901 aagcagagca tatttttctc ccatgatccc ttgtagttca gggaattctc ctaccatgtt
      961 ggttactaga tcaaatttat agatttcagc agcgcgttgc agatccatca attcttcctc
     1021 agacagtcct acttgttcgc ctatgatgcg agcgatgact tgtacccgtt gcattttctc
     1081 atagatgcta ccgatttttt catggaaagt aacagttttt aatttttcaa cgtattggtc
     1141 gattgaagct ttcttgtctt cattataaaa gaattccgca tcttctaaac gagcagtcaa
     1201 tactttttga ttgcctcgta ccacattttc caattttacc cgatcgccat tacgagcaga
     1261 aataaaatga ggaagcaaca taccttgatc gttccgtact tcgaaataac gttgatgttc
     1321 tttcatagaa gtgactagta cttcttcagg aacagataga tatttttctt cgaagtcgcc
     1381 agaaaagaca gttggatatt cgactagatt gttgacttct tctagtaaat cttcatctag
     1441 atcaatgatc cagtgatctt tttctgctaa ttcgtttgct tgtgtgatga tcatttcttt
     1501 tcttttttgc ggtgaagcaa taacaaattg ttcatttaat ttttcttcgt attcttttgc
     1561 atgcgcaaat gtcacatctt cgcctaagaa acgatgacct cttgaagctc tgtctgtttt
     1621 gatatccaag atctcaaacg ggattacttc gtcatctaac aatgccacga tccagtgaat
     1681 aggacggata tattcaaaat cgtattctgc ccaatgcatc gttactggga aagtgaggct
     1741 tttaatgaca tctgctaaac ctgtcaatac ttcttttgct tctttgccgt gagtgtattt
     1801 cgttacatag acatattcca cgccttttaa ttctctaaaa gtgatagcat ctgtcgtcag
     1861 accttgtccg cggacaaatc cttccgctgc tttcgtccag tttccatctg cgtccaaagc
     1921 aatttttttg gctggtcctt tgacttcttc ttcactgtct gcttgacgtt ctggaatgtt
     1981 tgttactttg attgctaaac ggcgcggtgt agaaaatgtt tcaatcgtat cataagtcaa
     2041 ttggttttca tctaaaaatt ttgctgtttt ttcttctaat tgtttcatgc ttggtgtgac
     2101 aacatgagca ggcatttctt ccagcccaat ttcaagtaat aagtcttttg ccatcttatt
     2161 cagcctcctt cacgttttct ggatttgctg tgtttttatt caataaaggg aatcctaatt
     2221 tttcgcgttc tgccacaaag attttggcta cagaacgagc catgttgcgg atacgggaaa
     2281 gataacctgc acgctccgtt acggatactg caccgcgggc atctaataaa ttgaatgtat
     2341 ggctgcattt caaaatataa tcatacgctg gatgaacaag attttcatcg atacagcgtt
     2401 tagcttcttt ttcaaaacga tcaaagttgc ttagtagcaa gtcttggtcg cttacttcaa
     2461 aagaatattt ggaatgttca tattctggtt gtttgaagat ctcgccatat ttcacgccat
     2521 cagcccattc taagtcatag acactttcaa cttcttgaat atatgaagca agacgttcta
     2581 gtccataagt aatctcagaa gtaactggtt tacaaggtag tcctccgact tgctggaagt
     2641 acgtgaattg tgtaatctcc atcccatcaa gccatacttc ccaacccaca ccggcacaac
     2701 ccatcgatgg gttctcccag ttgtcttcaa caaaacgaat atcgtgttct aatggatcaa
     2761 ttcctaaaaa acgcaagctt tctaaataaa gctcttggat attttcaggt gaaggtttca
     2821 ttacgacttg aaattgatga tgctgataca aacggtttgg gttttctcca taacgcccgt
     2881 cagctggtcg gcgggatggc tctacataag cagcattcca tggttccggt ccgattgccc
     2941 gtaagaatgt atatgggctc atcgtacctg ctcctttttc tgtatcataa gcttgcatca
     3001 gcatgcagcc gtttgatgac caaaattttt gtaatgttaa aatcatatct tggacggtca
     3061 attttttact catctgtttt gcccctttca atttttaagc gttgctgtca ataagaatac
     3121 aggaaagaaa acgacaaaaa gtccctatgt ctgattacag acatagggac gaataatttc
     3181 gcggttccac cctacttccg aataaagatt cggcagcttc atttatcgta ctcgcaagtg
     3241 cctcttcaaa aatcgtttgg gtccggcttc cactctcccg aactcgctaa accacgtgtt
     3301 ttttactgat cttggtcaat gtacgtattc attttgcagt tttcttgttt atataataga
     3361 tcctctcagt gaacgatcta tttaatctac ggttaataat agacggaagt ccctgtattt
     3421 gtcaaatagt tttgattttt ttgttgtatc tttcatttat tcttcttttt caggtatctc
     3481 tttttcaggc atatttttct ctggcatctt taatacgtgt gcccaagact tcatttgatc
     3541 aatgaacttt ttgcttttta gatgaatacc gacatattca tcatacaact ggtcaatgag
     3601 gtcacggatt gcctgcttcg tttcttcttt caagtggatt ccactgatct tatcataaga
     3661 aatagccgaa aacattcgaa cgaaataaac agcgcgagga tatgcatgat aacggtgttc
     3721 gtccattggc cagtgtttct cgcatatcac gccgccatat ttggaagaat agtcaaattt
     3781 tccttttgtt tccccgcata cgacacagtg cgtccaaatt ggcgcgattc cgaagcgttg
     3841 cagtatttga acttcaaaga tattcgtgat gatttctgca tcatctcctt ggtccatccg
     3901 ctgcagagct tgttgcgtaa attggaataa gtgcgggtca tattgatgat cttcgattgc
     3961 tgcatctact agatttagca aatacgtacc ataaccgctc aaaaagatat cttcttggat
     4021 gttccgaaac gcatggacgt ctttgacact gcttaaaaac gacaaacctt cacttagaaa
     4081 attaccgata tagactgctt cggtaaaggg gagcaaagcc ggagctaatg gctgattttg
     4141 ccgatggatt cctttgatat aaaacatcat tttgccagaa gattccgtaa agattttgac
     4201 taatttatct ttttctttgt aattacggct agataaaatc aagcctttcg attctgcaag
     4261 ctggctcata ttctccctcc taaaaaataa atctggaaaa gcagattctg ccgatccaga
     4321 ttatttatgt tacgatcttt cgctgttttt ctcaacgtac ggatttttat ccagtttatt
     4381 tctataccta acctataaga agtccagaat atcagtactc gtcttttcgg tagccgaagt
     4441 cttgcagata gacttttttg tctcgccagt ctttttggac tttgacccaa agttctagaa
     4501 atactttgtc tcctaaaaga ttttcgatat cctttcttgc tttcgttcct acttgcttca
     4561 gcatttttcc acctttgccg ataatgattc ctttttggct atctctttca acgatgatcg
     4621 tggcctggat atggatttta tcattctcgt ttcgcttcat cgaatcaaca acgactgcga
     4681 cagaatgagg cacttcgtct cgtgttaaaa acaagacttt ctcacggatc aattcagaaa
     4741 cgatgaagta ttcaggatga tcagtcactt gatcatctgg aaaatattgt gggccctctg
     4801 gcatttcact gactaataca tccattaagc gttcgacatt gtttccttct gtagcagaga
     4861 tcggaatcac ttgtgcaaaa ggcatctgcg tcgaataatc ttcgatgatt cccagcaact
     4921 cgtctggatg gatcttatcg attttattga taatcagata aactggagaa tgcacgtttt
     4981 ttagacgttc aataataaaa tcgtctcccc ggccgcgttt ttgatcagca ctgatcataa
     5041 ataagactgc atccacttct ttcaacgcag tgtaagctgc ttctaccata aaatctccta
     5101 gacgatgctt tggtttatgg attcctggtg tatcgataaa aatcagctga gcttctggtg
     5161 tagtatatac tccttggatt ttatttctag ttgtctgtgc cttgtcactc ataatggcaa
     5221 ttttttgacc cacgattcgg ttcaataatg tggattttcc tacattcggg cggccgacga
     5281 ttgcgacaaa ccctgattta tgttctggca tatacgttct cctttttaat taaacaacaa
     5341 atgatatatt ttagggacaa ataaaatcaa cccaatgatg acagcaaaac aagcggtcac
     5401 taaaactgct ccagctgcca tatctttgat ttttttccca atcggatgaa aatgaaaatc
     5461 cgtaaacatg tccactacat tttcaaaaac agtattgatg atctctacta tccaaacgag
     5521 aaaaacagct aaaagcagcc ataaccactc tatccgatca atctggaaaa tcacgcccat
     5581 aaataaagca aggataccga acgcaacatg tttcctcata ttgcgttctt cctcaaaaac
     5641 ggttttgact ccttggacag caaattccac ggacatcagg aaatgtttgt ttttctctac
     5701 gtttttatct tttgagtcca taggcatcca agatctcttt ctgtaaacca aacatttctt
     5761 tctcatcttc tggtgtcata tggtcatacc cgttgatatg caagaatcca tgtaccgcta
     5821 aaaagccaag ttcccgatca tatgaatggc cgtaagcttc tgcttgttca gcagcacgtt
     5881 caatagagat catgatgtct cctagtacac gaggcaatgg attctctcca tcttcaaaaa
     5941 tcactgggat ttcgtcttcg ccttcttctt ccagagcaaa actgatgacg tctgtcggtg
     6001 catcttttcc acggtaatca cgattgatta cttggattgc cgcattgtcc atgaaagtaa
     6061 cagacatttc tgtttcctct ggcagcttta aataagatgc tgcaaattgc agcaagtcat
     6121 cgatttcttt cattttctct tctgagactt ggtttgtttc atccataaag gtaatatcca
     6181 ttatacatcg cttctttcta ttcttcttgt tcttccttta tcttctcaac ttctgttttc
     6241 attttaggat atttgatccg agaatggaag gtgctactta aaccgctgat caatgatttt
     6301 tccacttttc ggatttcttt caaggtcaat ccactatcgt ctaattgacc atcggaaata
     6361 cgctcttcga taagattatg gacaaaactt tcgatttttt cgctcgttgg atgatccatt
     6421 gcccgtactg cagcctcaca actgtcagca atattgacga tccctgcttc acgactttgc
     6481 ggttttggtc caggataacg gaattgctct tctgttactt ccggattgcg ttctttcgct
     6541 ttgatgtaga aataacgcat tagcgtggtt ccatgatgct gtttgcaaat atcgatcacc
     6601 atttgcggca tattataatc ttccaatatt ttggctccat ctgtcacatg tccaaagata
     6661 atatgtttac tgtcttctgg caataagaaa ttgtgcgggt tttccgctcc tgaaggcaag
     6721 ttctcaacga aaaagctagc atgtttgatc ttgccgatat catgataata gcaagctact
     6781 cgagttagta aagaacgtcc gccgatttct gctacagcgt tagcacttag attagctacc
     6841 atcatactat gatgatacgt acctggcgct tcttccagca actgtttcaa taaaggatga
     6901 tttggattgc tgagttcatt taatacaatt acactgtcat cattgaccat caattcaata
     6961 tatgggtgta gaccgatcgt cagcaagaat gagaagagtg caccagtgaa cccgcagaca
     7021 agcattaacc aagtcgttgc atcaccaaag ctcattcctt gatagacgat caaaatgaca
     7081 tccatcatca caggaaaaat aatgacccac atggcagcag ataatccttg ttctgagatc
     7141 cgtttacgtc tgacaatcgt tgccatgagc ccagagaaaa cataagacat caagataatc
     7201 gttagaaagt tcgtgccaat cgaatcataa aaaatgaaaa gtgcggatac tgcttggaaa
     7261 ataccagcca tgatccctgc tcttcgattc aagaaaaagc ttaaaacaag tggtgcaaaa
     7321 gcagcgggat aaaacagcgg gatataagta gcttgttccg tttggaataa ttggaaaaat
     7381 ttcatcagca ctatgctgac tgacatagct gtcacataga aaagaacgta ttttgttctt
     7441 tctcctgtat tttggaattg aagtgaatta taaatcagta cgccgatttg aagcaaaaca
     7501 gctaaaacca tggcaattag cggaaaaatc gaagttgttt gattagtcag tcctagtaat
     7561 tccaattttt tcatagctga agcatcaatt tgattacctt cacgaacaat gatttctcct
     7621 tggaagatca tcactggttg tacagcttct cgtgcggatt gtttcaattc ttctgtcttt
     7681 ttctcattca atacgtcatt cactacgata ccttgatcca ctaagtagcg aatcatttgt
     7741 tgttgtgctg gtgtgacatt caaatattgg atttgctctt ctgcttcttg tttaaaagct
     7801 tccaattcac tttcacgaac ttgtttgctc atctgttcgt caatgagctt cagactctca
     7861 tccctcacag tatgaatctc agtttcagtc atttcaaata tcgtcgaata aaaattgttc
     7921 ggtagttttt gataaaacac aacattttct gcattcacat tttcaaaatt tttcttcagc
     7981 gcggcgatcc gctcttctgt agtaggcttt gggatatttt catcttcctt tgccttatca
     8041 atcttttcgt cataagattt gttgatggca tcattcgtct tatcgatcaa ttcaaatagt
     8101 tgcttgatcc gattgttctg gtcatctgca agatcttttt ggtaagtgta ttctggagtg
     8161 actgcttctg ctgccagttt tcttttttgt tcggtttctt ccgtgttctc gatcgttttg
     8221 ttcgcacgga tactttcttc tgctacttgg ccttctctga aatcattggc cttttgtttg
     8281 acactactaa atgtaacgcc gcagataatg ataaaaaaca agaacagcag gaaaggcaat
     8341 gctgcctttc caagtttttc ttgtagtttc tgcagtgttt tattcaacat gtgcttatcc
     8401 tcctaagcaa agcttattct tgatggagat ctgccttttc ataagctttg atgatttcgg
     8461 caactacagg gtgccgaaca acgtcacttg cttcaaaatt aacaaaatcg attttcttga
     8521 tttgctttaa tgttcgttct gcatgaacaa gaccacttgt tgtccctcga ggcagatcaa
     8581 tctgactcgt atctccattg acaatcattt ttgattgata accaagacgt gtcaggaaca
     8641 ttttcatctg agcaactgtc gtgttctgtg cttcatccaa aataacgaat gcatcatcca
     8701 atgtccgccc ccgcatgtaa gctaaaggag caatttcgat cacgcctcgt tccatcaatc
     8761 ggttcgtatg atctaatcca aaaatttggt ataaagcatc ataaacagga cgcagataag
     8821 gatctacttt ttcttttaga tccccgggaa gaaagcctag attttcccct gcttccacag
     8881 caggccgcgt caaaatgatt ttttgcactt cacctttttt caaggcagcg attgctaata
     8941 ctactgcaag aaaagttttt cctgtcccgg ctggtcctac gccaaatacg atatcatgtt
     9001 tggctaccga ttcgacatat ttcttttggc cgctgttttt tacccgtata ggttttccat
     9061 tacggtcttt gacgatctct tcctcataca tctcaacaaa ataatctaat gtgccttttt
     9121 gccccatttt cagtgccgtc acgacatctg gtgtacttac atggattcct cgtttgatca
     9181 attcctgcaa tgtccgaatg actgaggcag ccaaggaaat ctgggattgt tcgccaatga
     9241 tctgaatgat ttctccacgt gtatggatgg ttgtttctgt tgtttcttca atcagtttta
     9301 tgtgcttgtc gtgtgcacct aaaagcatgc tgacatcatc agcagccgtc aatctaatct
     9361 ctaaagaact agactcttcc gtcaaaaata gacatcccct ttttttcgat tcattctttc
     9421 ctattttacc atactcagaa gaaactatat agcaaataag aaaaggttct aaaagagttg
     9481 cttaaccata agtaccaaga aacgttaaaa aatagctgct tccattctct aaaggtctcg
     9541 tttgaataaa aaaagctgat catgtaagct atgcataaga tagaggacaa gtattccgtc
     9601 taacttagca agtattctct gggtattttt cttgtttcaa aaaaagaaaa caaaatattt
     9661 gaaatattct tgcatttcaa aaaaaacagg tgtattataa cgtcaacaaa taaatataca
     9721 gcaaagcgtc gaggaaaaca gtaggctatt cagtgattta ttcccagtga gtcatgtaag
     9781 tgagaaatga caataaatcg aatagacgaa catcatttcc gagtcaatgt cgaaaacgta
     9841 gatcattgtg gctgcctcca ttatcaggcc agcggataac tttatcgaaa agcgtccgtg
     9901 aatgaagaag cttttttaag cgaaaaaagg tggtaccgtt ctagaatcta gagccctttt
     9961 cccaagtgga aaagggcttt ttttatattt taaggtggtg gttttcatgg aatctgatat
    10021 tagtggtatt tctagtttct gcaacgttta ttttgttact caaaatgata attattggag
    10081 gaaaaattta tggaagaaac aaaaacttat tcatggaagc aattattgat ggtcagttca
    10141 cttatcttcg ggatgttctt cgggtcaggt aatctgatct ttcctgtcca cttaggtcaa
    10201 atggctggat caaactggat cagcgctggt gtaggatttg ccatctcagg cgctcttttc
    10261 ccattattag ctatcttagc tgtagtagtg acaaaaagtg atggtctgta tgacttagct
    10321 aaacctgtcg gaaaatggta tgctgccttg ttcttgatcc ttgttcattt aacgatcgga
    10381 ccattctttg gtacaccgcg gacagcagca actgcttttg aaatggctgc taaacccttt
    10441 ttgcctgaaa aatatgattc attaggtatg tttttattct ctgctctttt ctttttactt
    10501 gcttatttcc ttactgtaca tccaacacgt ttggtcaaat atgtcggaaa gtatttaaac
    10561 tccttgtttc ttgcattatt agctatcatt tttgtcgttt ctttattcca acccatgggg
    10621 aatctaaacc aatctgctgc agattcttat cagacgaacg ctttgacaaa tggcgtttta
    10681 gaaggataca acacggttga tgcagtagct ttacttgctt taagtgtcac ttttgtccat
    10741 gcagttcgtg atcttggttt taaagataaa aaagtcacag aattaacagc aaaagctggt
    10801 agcctgagcg ttgcgttaga agtcatgatt tattttggtc tggtccttct cggtgcgatg
    10861 agtttgaata agatgtcttt atcagaaaat ggcggaactg cactttctca gatcactaat
    10921 ttttatttag gtaacttcgg tgctagcttc ttaggggtaa tggtcacatt aggtgtcttc
    10981 actaccgcta tgggactcgt tgtttctttt gcacaagatt tccataaact gttccctaaa
    11041 gtcagttata tgacatggct gcggttaacg acttttgtct cttttgtcgt tgcgaatgcc
    11101 ggattggata atatcatcca atggtcttta ccagtattga tgcttttgta tccattgtca
    11161 cttgcgttaa tcttgctttc cttaacagca aaattcttcc aaaagagtcc atttgtctat
    11221 caagtaacga tgttcttttc tgccgttcca gccgtattgg atatgttggc aaattcgcct
    11281 gcattagtga gtcagcaaac tgtcgtagca agcttactag gattttatca tcattatgtt
    11341 ccttttgctg cattaggact tggctgggtc gtcccaacgt tgcttggtta cgctggcagc
    11401 ttgctctttt attatgtata tcgcgtatca ggatataaac aagaagcaag tgagttacca
    11461 gaagaataac caaatcaaac acaatttaac ataagagata ttaaacagga aaaa
//
LOCUS       DAIGSZ010000078        11356 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.080, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000078 DAIGSZ010000000
VERSION     DAIGSZ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.080"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..1030)
                     /locus_tag="NOB31_002418"
     CDS             complement(<1..1030)
                     /locus_tag="NOB31_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0974598.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="NOB31_002419"
     CDS             complement(1112..1801)
                     /locus_tag="NOB31_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI0974599.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="NOB31_002420"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="NOB31_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HCI0974600.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="NOB31_002421"
     CDS             complement(2328..2831)
                     /locus_tag="NOB31_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HCI0974601.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="NOB31_002422"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="NOB31_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HCI0974602.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="NOB31_002423"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="NOB31_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HCI0974603.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="NOB31_002424"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="NOB31_002424"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HCI0974604.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="NOB31_002425"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="NOB31_002425"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HCI0974605.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="NOB31_002426"
     CDS             complement(6443..7462)
                     /locus_tag="NOB31_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCI0974606.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="NOB31_002427"
     CDS             complement(7635..8540)
                     /locus_tag="NOB31_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI0974607.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="NOB31_002428"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="NOB31_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HCI0974608.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="NOB31_002429"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="NOB31_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HCI0974609.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="NOB31_002430"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="NOB31_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCI0974610.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="NOB31_002431"
     CDS             9753..10397
                     /locus_tag="NOB31_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCI0974611.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="NOB31_002432"
     CDS             complement(10453..10956)
                     /locus_tag="NOB31_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCI0974612.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
BASE COUNT         3312 a         2361 c         2078 g         3605 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gctttt
//
LOCUS       DAIGSZ010000079        11242 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.081, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000079 DAIGSZ010000000
VERSION     DAIGSZ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.081"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="NOB31_002433"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="NOB31_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HCI0974613.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="NOB31_002434"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="NOB31_002434"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HCI0974614.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="NOB31_002435"
     CDS             complement(2169..2906)
                     /locus_tag="NOB31_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCI0974615.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="NOB31_002436"
     CDS             complement(2997..3524)
                     /locus_tag="NOB31_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974616.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="NOB31_002437"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="NOB31_002437"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HCI0974617.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="NOB31_002438"
     CDS             complement(4401..4886)
                     /locus_tag="NOB31_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HCI0974618.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="NOB31_002439"
     CDS             complement(5039..5236)
                     /locus_tag="NOB31_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974619.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="NOB31_002440"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="NOB31_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HCI0974620.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="NOB31_002441"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="NOB31_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HCI0974621.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="NOB31_002442"
     CDS             9211..9423
                     /locus_tag="NOB31_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HCI0974622.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="NOB31_002443"
     CDS             9425..11104
                     /locus_tag="NOB31_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCI0974623.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3256 a         2428 c         1971 g         3587 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tc
//
LOCUS       DAIGSZ010000080        10854 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.082, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000080 DAIGSZ010000000
VERSION     DAIGSZ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.082"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            1..329
                     /locus_tag="NOB31_002444"
                     /pseudo
     CDS             1..329
                     /locus_tag="NOB31_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(231..947)
                     /locus_tag="NOB31_002445"
     CDS             complement(231..947)
                     /locus_tag="NOB31_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HCI0974624.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(1071..1256)
                     /locus_tag="NOB31_002446"
     CDS             complement(1071..1256)
                     /locus_tag="NOB31_002446"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974625.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            1483..2756
                     /locus_tag="NOB31_002447"
                     /pseudo
     CDS             1483..2756
                     /locus_tag="NOB31_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2863..3894)
                     /locus_tag="NOB31_002448"
     CDS             complement(2863..3894)
                     /locus_tag="NOB31_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974626.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(3901..4731)
                     /locus_tag="NOB31_002449"
     CDS             complement(3901..4731)
                     /locus_tag="NOB31_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0974627.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(4728..5543)
                     /locus_tag="NOB31_002450"
     CDS             complement(4728..5543)
                     /locus_tag="NOB31_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI0974628.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(5540..6364)
                     /locus_tag="NOB31_002451"
     CDS             complement(5540..6364)
                     /locus_tag="NOB31_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HCI0974629.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(6354..7454)
                     /locus_tag="NOB31_002452"
     CDS             complement(6354..7454)
                     /locus_tag="NOB31_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCI0974630.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            7632..8417
                     /locus_tag="NOB31_002453"
     CDS             7632..8417
                     /locus_tag="NOB31_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HCI0974631.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            8450..8833
                     /locus_tag="NOB31_002454"
     CDS             8450..8833
                     /locus_tag="NOB31_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCI0974632.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            8907..9041
                     /locus_tag="NOB31_002455"
     CDS             8907..9041
                     /locus_tag="NOB31_002455"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0974633.1"
                     /translation="MCWSPMLVKFRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH
                     "
     gene            9010..9246
                     /locus_tag="NOB31_002456"
     CDS             9010..9246
                     /locus_tag="NOB31_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0974634.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(9324..10295)
                     /locus_tag="NOB31_002457"
     CDS             complement(9324..10295)
                     /locus_tag="NOB31_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCI0974635.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         3231 a         2522 c         2071 g         3030 t
ORIGIN      
        1 actcagatgt tgaaagtcaa agaaaagttg actattttag aattaaaacg tacccgtttt
       61 ctatgctatg attgtgggca gaccttttct gcgaaaacgg acttagttga tgaacatcat
      121 caactaacaa aggaactgaa acaggcgatt ctcatagaac tgtacgaaaa tcaatcacgt
      181 aatctgaaaa tcagaagaag taccgtcggc tcaagcgata ttggaaactc ttactcaaag
      241 attccacgac attggagccg ctcaaacggc attatcatcg actgtttaaa cgaccaatta
      301 gtcaaacaga aatcgtcgat gaaccgttgt gcacaatggt gtcctgaacg tacagcgaca
      361 ccttccatat ccagagcagt cgccacatca cggggatgga tgccatccaa attaaaagca
      421 accacgccag tatgatgttc aggatcttgc ggtccgtaaa tggtgatacc gccgatcgct
      481 tgtaatttag gtaaaacgta ggcaaccagt tcttgctcat aacgatgaat attctccata
      541 ccaatctcat tcaagtaatc gattgctcct gcaatgttcg gagtaccagc ttcaaatttc
      601 catggcagct ctttccatga actatcgtaa agattgacaa aatctatcat ttcaccgccg
      661 aattcgactg gctccatttg ttctaacaat tgacgtttgc catataatac accgattcct
      721 gtcggcccgc acattttatg cccgctaaag gcgaaaaaat ctgcatccaa cgcttgtaca
      781 tcaactgtca tatgcggtgc tgcttgggca ccgactggac tatcctcaac tacaacagcc
      841 tgttcaaccc tcagccgttt caagcacaac aaataacctt ctggatctgg tttgccgacc
      901 tgaagatcat cgatcgtcac aaaggaatca attttttcct taatcatcgg atgtgcttca
      961 aaaaaatagt ctagctcccg cagttcagaa ttgagactac tccgattttc cagtgctgct
     1021 gatccgctgc tcaaaatgtt cagcatccac tggtctccca accgcttgac ttatcccttc
     1081 ataaaaggac agttctgctg ccgtcccaac accttgttga tagtctgcaa aaggaatttt
     1141 atagccgaac tgctccagta aataggcttc agtaaatagt gatgaatact ctcgtaaaac
     1201 atccattcac tgtcaatcat cgtcccatca aaatcaaaaa taagtgcttt ggtcatcttc
     1261 tttccccctt acccaaaaca agcaaaagct gtgtcctgct ctctctacag tatcagcata
     1321 aaaactgccg tctgaaaagt caaaggtgaa agaaatgtgg cgctataatt tctaggactg
     1381 atagtaaatc attctatcag tccttttgag cataaaaaaa caaaacatac agaagctccg
     1441 ttagaattga atcaccacaa cacaatcaaa ggagcgttct gtatgcctga tcttcatctt
     1501 atcaaactat tactaggaat caaagatgga aacattcaaa tcactcatgt cgagaagaaa
     1561 aaaatacatt caatcaacag tatcgttgtt tctgccacgc tcattaaaac gattcagccc
     1621 tgtcctcagt gtaaacaggt gaatcaacat gggctgatcg ttaagaacgg aaagaaaaaa
     1681 tcgctggtcc ttctcaataa gtgtgcgaat caacggactt atcttgcttt ggcaaagcaa
     1741 cggtacctct gtcgtggctg tcacacctat tttacggcga atacctacat tgttgaaaaa
     1801 aactgtttta tcgccaaaca agtacattat aaaatattgg aggaattgac tgaaaaacaa
     1861 gcaatgacga cgatttctaa acattgcggc gtttcttggt caaccgtttc gcgaacactc
     1921 gcttctctgc tccccatgac aaacgtgaaa ataaattggt tgcctcgctg ttcattggta
     1981 gatgaatttc gttcattgaa aaatcaagtc ggtccctatt ctttttcttg tatggatggc
     2041 gatactggga aattactgga tattcttcct tcacgtaaga agaaagatct catttcttat
     2101 tttatgcaat ttgaacgacg tgcacgttta aacgtaaaaa tactcgtaac agatatgaac
     2161 gcctcttatg ctttgctgat aaaagagtgc tttcctcatg ccaaactcgt tgtggatcgc
     2221 tttcacatcg tcaagcacct cattcgcagt tttaaggata tttgactatg agtcatgaaa
     2281 agcttcgacc gaaacgatcc aatacaagcc aaacactatc gacaagtgaa ggctttatct
     2341 cgacttctga tcaaacgaca ggacacgctt gtttatgata aatggacaaa atggcgtaat
     2401 tttggttggg cctatttaac cgaaagtgaa gtcgtagaac gtctactttc tacttctgat
     2461 gaactacgaa tagcttatgc ttactatcaa gaaattcttc aagcttttta tgacaaagaa
     2521 gcggacatct tctttcagct tgtaaaaaca atgcccaagt cggttccaag agaactgcat
     2581 catataaaaa aagcgtttat aaactatgaa tccggcattc gtttagcctt agagttgcct
     2641 tactcaaatg gcaaaataga aaatctgcat acccacatca aagcattgaa acgaatagct
     2701 tacgggttag gatgagaacc agaattttct taatcaatca tctgatcact tattaaacat
     2761 aaaaaaacat ctaaagcaga aaatcaattc taccttagat gttcttatat cactctatca
     2821 gtcctatttg acaaagagcc agaaatgttt gccgactata cactagcttt gttgtgcaaa
     2881 atgctgagta tcaatttcca cagggattgc tagaatatct ttcagctgaa tgtataaggc
     2941 atcgctaatt ttctcttccc gatcgttcaa ccgatccact aaaatttctt tgccctccag
     3001 cgtttgaaaa acataccgtt gaatgttgcc taaaataaat gattccttcc atagaaccgg
     3061 aatcttaacc ccctgaggaa ccggttcaaa ttgaatcagc tccggtctta aataataaat
     3121 gcagcgattg cccttagcgg aaaactcgtg ggtatactga ttcagctcat accattcgaa
     3181 acgattatag ttgccgataa attccgcaac aaatcggctc tgaggattct gatacaattc
     3241 cttcgaggtg gaaacctgag ccacccgccc agcttccatc acaaaaatcc gatcactgat
     3301 tcgcatcgcc tcttcttggt catgagtcac aaaaatcatc gtcatcccta gcgattgctg
     3361 gatagcgcgc aaatcccgct gcagctgttt tctaattcgg gcatccaaag cacttaatgg
     3421 ctcatccagc agcaggactt tcggttcagt gaccaatgag cgagccagtg ccacccgttg
     3481 tcgttgaccg ccagaaagaa actggacatt tttatctgcc tgctccgtca tatccaccaa
     3541 tgatagcatc tcaaaaacct tttcctgaat cacctcagga ctcagcttct ttaccttcaa
     3601 accaaaggct acattttcaa aaacagtcat agttggaaac aatgcatact gttgaaaaac
     3661 aaagccgata ttgcgatcct tcgtaggctt atcggcaata ttctcattgt ccagcacaat
     3721 ctcaccgctc tttggttgtt ccaatcccgt gatacagcgc agcaacgtag actttccgca
     3781 cccgctggga cctagtaaag taaccagctc acccttttca atctgaattt catcaatagc
     3841 taaaatctgt ttttcatcaa aaaacagatt gagatcatgt atttctaaaa acattttccg
     3901 tcacaactcc tttaagggct tctttttcga ctgcttctct tccctcgtct gcttaaggga
     3961 cagctgttgc ttttgtcgat aagtcagcat aaaggtagtt aaagcaattc ccaccataaa
     4021 cagcaaatac aaaaccatca cagcgctagc caaatggccg ttttcgttca tccgccgcag
     4081 catatagatg cgtaccgtct gaaatcgacc gccaatcaac aggttcgtca gcatgtactc
     4141 cccaaaaacc gaagaaaaaa tcatcagaga aactagggtc acaccgatac ggatgtttgg
     4201 aaacagcacc tggataataa tcgtagacat cggggcgccc aaggtttctg ctgcatccac
     4261 taattccttc agattaatta agcgcatctg gttgttaaga ctaagataga caatcggcaa
     4321 cgccgtaata aacaatgcac ctaccaacac tacaaacatt gggataccag tttcagcata
     4381 cgttcgaagc aaagccgtta ccaaaatcac tcctggtaaa gcatacggca gcaggagcag
     4441 cttttccagc caacgattca aacgagggaa atacaaatga atccaaataa tggtgggaat
     4501 catcaacaac agaatcgtca ccaagaccac acctgctaat aaaagtgagc gacccaccgc
     4561 agcaataaat tccctgtccg tcagcagctg ttggaaccat tgcaaggtaa aatcactagg
     4621 taaaagcgat tttgaccatt tagtggagct ggcatacaaa atcgttccaa taatcggcag
     4681 caagtaatac aggacaaagc agaacaaaat cggttttatt aactttttca cgtctgcacc
     4741 accttgcctt tcttttgaat aatcaacatt gccgttacca gcaggacacc taaagcgact
     4801 gccaacgcac tgcctaaatt aggcttggcg aacacatctc ccgacactaa agccgcaatt
     4861 cgaatcgtta aaagatttac attactgctg gtcagggcat acgctgtttc ataggtcccc
     4921 atgccattag caaataagat gacaaaggtg ctggcaatcg atggtcgcaa aaaaggcaaa
     4981 gccaccttga accaagcata cgctgatgaa gcgcccagca attgtgcgga ctccagccat
     5041 tcctttttca cttccttcat gctgggatac aaaaacaaga cccctaacgg aatttggaaa
     5101 taggtatacg tgatggtcaa tccccaccaa gaatacaaat tgaagtccgc tagaaatggc
     5161 aaaatcattt tcagcacacc tacattcccc aacaaaataa taaaagagaa tgccagcgga
     5221 atcccagcaa aattagctgc caaattggaa acaaaggtga ttttctcctg caatttagtc
     5281 gatagattca ttaagcataa acataaaata aacgtcccga ttaacccaat cacactggag
     5341 ctgacagcaa tcagtacgct gttaacaaag gcctgtgtgt aatatttgtt gctgaaaata
     5401 tcactgtaat tggccaatgt ccactggtta gttaaatcac tgtgcaagct gcacagaacc
     5461 ataaaaagca gcggcagcag taaaaatgca cagaagataa aggaggcagg aaccagaacc
     5521 aagcgttttt tcatctcttt catcccctca tcaattcttg aatgtcctgc attttctctg
     5581 acggtgcaat tcctaataac cagcaaaaca atggagccgc cagcagctgt ggtacagttt
     5641 gttccttcag cttttggcgt ttatttgaaa tcaaataaaa aggaacttca cgatgtgcag
     5701 ccaagctgcc gccatgcagt ccgtgcgcat ccatcccgtg atccgcagtc accacgactt
     5761 gataaccttt ttgcagccat tcaggaaggt aaatagccaa taatctgtcc gcctgattaa
     5821 ccgctgctgc atattcatga gaatcggcgg taaatttgtg accgacatca tcaatattca
     5881 tcgaatgtac gaccaaaaag tctggctgat actgattcac taaataatgg gcatccgcaa
     5941 ataaatgcga atcagggtaa gtgtcctcac tataaaagat gccatgctga atcagtcgct
     6001 cctcctgatg ctggatgcga tcaaccaaac gattataggg ggcttgattg tacaactcgc
     6061 tgtaccagtg gtaagcggcg gctcctgttt ttccgccagc ttccttaact aattcaaaca
     6121 gcgaccactc tttggatcgc tgagcatggt aattactata gatgccattt tcataggctg
     6181 gaacgccggt catcagtact tcgtataacg gacgtgaatt gctgggcagc tcacttttta
     6241 ccttcaataa gcttgcttgc tggtgctcaa ctaaatgatt catgaaccca agctgggcga
     6301 cggctgtgtc gtagcgacag ccgtctagta taactacaat cagtttgtca agtctacttt
     6361 gcataggtca gtacctccgc ctgccaaagc tctggaagct ctacagaggt cttgttccaa
     6421 gcttcattgt cttcaactgg caccgccgct tcataagcat cctccggcag taatttttca
     6481 gctacttctt taggcagctc taccttgcga ataggtcgcg catagccctt tgccaaattg
     6541 atttgccctt catcagataa aatatattcc cgtgctagct ttgccgcatt gggatgaggg
     6601 gcatttttat tgattaaggt tgtatacccg ctaatgatgg agccgtctgt tggcacagtt
     6661 acctcaaaac gctcggagtc aatttggtca cgataattta gtccattgaa gtcccaaaca
     6721 actgccacat cgatttcacc tttttcaaga tttgctacgc tggcatcaac ggtggacaaa
     6781 cggccttttt ctgccatttt tttgtagtaa ttcagacctg gctgaatatc cttttcgtca
     6841 cctccgttgg caatcgccgc agccaataca gcaaattgtg cttggttggc aatcgtcaca
     6901 tcccccacgc taacttgata gtcaccctct tgcagctcct tccagctagt cggtgcttgc
     6961 ttcacattct ctttatcggt gataaaggaa atggttcccg tatagcttaa caaccaatcc
     7021 ccatcatcat cctttgccca atccggaatt tcctcccaat agttggtctt ataaggtaag
     7081 gttaactctt tgctttcagc caacggaccg aagctgatac cgacatcacc aatatcggcg
     7141 gttccatttt ttccttctga ttcaaactta gccaattctt ctgcactgga catatccgta
     7201 tccacgtgac ttaagccgta ttctttttca aggtcgttcc aagtgcctac ccaatttgcc
     7261 caagtatccg gcattcccaa gctggcaatc tctccttctt ccttggcttt ttctataatc
     7321 gtatctaaag agtcgtctgc cgcagccgat tgcttcgttg cttcacctga gccgcagcct
     7381 gtcagcagga tacttactgt tgctgcacaa aataaaccga tagtcatgtt acgaattttt
     7441 tcattcattt tcattcattc ttctcccctt tcgataattc cattctaaca aagctttgta
     7501 atgagagaat cagtttcttg aaaaggtttc atgaacaatg taaaggttgt atatggtttg
     7561 taaatttcga cgaattcccg ttaaccttct aaagcttttg cggtatgata gtagaaaaaa
     7621 ggaggctccc tatgcagtat tatgatcagc atctccacac gtatttttcc tttgattcag
     7681 aggaaaaatt tgaaaactat ttagcctatc agccggagtt tttcgtttct acggatcact
     7741 ttgatttaaa caatccatct accggaaaag atgacattcc ggattatcca gcctatataa
     7801 acaaactgga ctctttaaaa gaaacctatt ccaccaaatt tctgcgaggt atcgagattg
     7861 gcgttgttcc aggacaagaa gagcggatcg tggattacct cgctcagcat ccttatgatt
     7921 taaagctggt aagtattcat caaaatggcc gctttgatta tatggacgat gtggttttaa
     7981 ccaaagatcc cattcaaact accaaggaat attttgatca gatgttgcag gtcttgacgg
     8041 attttccaga aggagatatt ttgactcact ttgattatgg attacgccgc ttcaccttca
     8101 cagcggaaga attcgcggag cattttgagg ctcagctgct aacgattttc aaaaaggttg
     8161 ttgaacgaga attggcgatg gagttaaatg ccaagagctt cttgaaatac ggcaacgaag
     8221 acctttaccg ttatgccgtt cctttgtatc aaagtgtcgg cggaaagctc tttaccttag
     8281 gctcggatgc tcatgttgcc gaagattatc agctgggctt taaaaaaatg agtcagctgt
     8341 tggcagactg tcaggtagaa aagttgctag tcattcaagg aaaagaacgc cgcctgacgc
     8401 cgctgccgat tttgtgattc ctatataata gaagaaagtg gtgaaaaaaa tgagcaacct
     8461 gtgggactac aatcaagagg cacccatcca ttatttaatt gcgcgacatt gggatgcgtt
     8521 gaaaattgag gcggtttgcc gatccttgtt agcagccgtt ccaaaacaac aactggaaaa
     8581 ttttttggtg gctgacagct tgcagcggga aaaagttcag gcttattttg cagcctttaa
     8641 agatcagcct ttggaatatt tgcatgcgca gtttcatctt ttttatcaag tagccgcccc
     8701 agatgactac aacgatttac gaggacagct gcaattgacc tttcaagcgg atgaaaccgc
     8761 ctataccgtt ttattgggaa tggctcgcct tggtgatcag gcgaaggtcg agtggcggat
     8821 tttcgatatt tgatggcagg atcaaggcgt ttcagttgca aaccttcctc tctttcaatt
     8881 agaaaaaccg cagcaggaag aagtttgtgt gctggtcacc gatgctggtg aaatttcgtc
     8941 tccgcttatt tcctgaccaa gctcccctgg ctgtagccaa ctggcgctcc ctagctgagc
     9001 aaggcgttta tgacaacaca cctttcggct cgtgtcatta aggaatttgt tattcaaggt
     9061 ggcgctttgg atggttctgg tgatgaagct gtttccagct atgagggctt tttcgctgat
     9121 gaagtgcatc gcggacttta tcattttaat ggcgccttgg ccttagggga ccacggcccc
     9181 cacaccaacg gcaaccagtt ttttattgtg caaaacacaa aggcgcaggc tgacctgcta
     9241 atgtaaagca agcatacttg gagcttggag gactaccgga gctggatggt cgttatactg
     9301 tttttggaca ggtataccaa gggttagaaa tcgtagcagc gatcgcagct cagccgacaa
     9361 acagtgaaga tgtaccgatt gagccagtgt tcattcgaca aattaacttc gaaaaaacat
     9421 cgtaaaaaga cactcactga cttcagcaaa agctctattc ttgagctggc tgcagctagt
     9481 gagtgtcttt catttatcca taagataaag cttggattca ataaataaat aaatgttttg
     9541 gttaaagctg tgaccagcaa atgaggaacc gtgcgagcca gttgatctgc caatgcaaac
     9601 atttctttag gtgaaggcgc tggcgtgtct gccaacggat actccagtcc caatgcttgg
     9661 taaccgtgca taccatagca gtggtacggt agtaattcta acggtacgaa ccgatcaaga
     9721 tctgccacaa aacaagcaat cgtcagcagc tcggtcaggt tcatattgat acctggaacc
     9781 acaggaactc gaattcgcac ttcgcagtta ggatactcaa ttaaaaagcg acgaatattc
     9841 ttcaaaattt gttggttatc taagccggtc cattgtttgt ggagcttgct ggtaaacatt
     9901 tttacatcca caaacaatgt atccacatag ggagctacct tttggatttc attataagca
     9961 ccacaaaagc tggtttccag tacggtattg attccaatgt atttcgattt ttgcaaaatt
    10021 tctttagcaa aatccgcctg aaccagtgcc tcgcctccgc taatggtcac tccgccatcc
    10081 gagtgaaagt aaaaaacagc atccttctca atctcatcca ttacctcttc agcggtcatg
    10141 gtctggccaa atcctttttc aatctgcttg ctttgtgatt cgggaatcga acaccaggca
    10201 cagcgtaatg ggcagccctt taaataaaca acggtccgta aaccagcacc atcatgtaga
    10261 gaaccctgtt ctattcttaa tactgttcct tccatataga tttttgaatt acacactagt
    10321 ttaaactaaa acacacaagg aaaaacttac catttaatca taaaattagc tcatataaat
    10381 atactaggat gtaaaataga ctggtcaaaa tctggtcaaa aaagaggact aatacaggta
    10441 gtcctctttt ttgttatttt aatattctaa atcatttttt attggtttat tcccttattc
    10501 gatgtagact caaatcacta tatcactaga tatcaaacgg cgtcatacgg aatcaaaaac
    10561 atcaaatttg acctgttaaa tggtcattga ataacattca aaatcaataa aacggagtca
    10621 gacacggagt caaaaacgct gagagtaaaa aatatataca gccttgtagg taaagtacca
    10681 cagggctgta tattttttat ttcagattac cttaaatgat tccatttact ttttatctca
    10741 ttttttccta ctagttagta tcaaatactc tcctattttc tcaataaact atttttggat
    10801 acatggtatc tgaaacagct aaaaccttgt cattacagca aaaaatcacg ttat
//
LOCUS       DAIGSZ010000081        10732 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.083, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000081 DAIGSZ010000000
VERSION     DAIGSZ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.083"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(45..1184)
                     /locus_tag="NOB31_002458"
     CDS             complement(45..1184)
                     /locus_tag="NOB31_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0974636.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(1298..1882)
                     /locus_tag="NOB31_002459"
     CDS             complement(1298..1882)
                     /locus_tag="NOB31_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HCI0974637.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            complement(2009..2440)
                     /locus_tag="NOB31_002460"
     CDS             complement(2009..2440)
                     /locus_tag="NOB31_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HCI0974638.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFTASHFEYSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(2458..2778)
                     /locus_tag="NOB31_002461"
     CDS             complement(2458..2778)
                     /locus_tag="NOB31_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0974639.1"
                     /translation="MITFERIKELAKKQGKSLNKVEEDLGYGKNVLYRLKNSNPSTER
                     LQEIADYFDVSVDYLLGREEKETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            3072..3212
                     /locus_tag="NOB31_002462"
     CDS             3072..3212
                     /locus_tag="NOB31_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974640.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            complement(3209..3388)
                     /locus_tag="NOB31_002463"
     CDS             complement(3209..3388)
                     /locus_tag="NOB31_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974641.1"
                     /translation="MNKKTDEIAADLVVAWLNHESQVSTKGESISPKEIAQAYLDIHY
                     AVIYGQLPEDRKNDD"
     gene            3469..4215
                     /locus_tag="NOB31_002464"
     CDS             3469..4215
                     /locus_tag="NOB31_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HCI0974642.1"
                     /translation="MNTPQIFSFEQHEVRTFLENDIPYFVANDVAKTLGYKNPSKATN
                     DHCKKSIETWGNDSLGRRQKFKVIPESDVYRLIIKSNLPSAEKFEAWVMEEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            4230..4433
                     /locus_tag="NOB31_002465"
     CDS             4230..4433
                     /locus_tag="NOB31_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0974643.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            4449..4787
                     /locus_tag="NOB31_002466"
     CDS             4449..4787
                     /locus_tag="NOB31_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HCI0974644.1"
                     /translation="MQYLEAKIPVPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            4774..4953
                     /locus_tag="NOB31_002467"
     CDS             4774..4953
                     /locus_tag="NOB31_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974645.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(4996..5466)
                     /locus_tag="NOB31_002468"
     CDS             complement(4996..5466)
                     /locus_tag="NOB31_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974646.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            5553..6251
                     /locus_tag="NOB31_002469"
     CDS             5553..6251
                     /locus_tag="NOB31_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HCI0974647.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            6429..6770
                     /locus_tag="NOB31_002470"
     CDS             6429..6770
                     /locus_tag="NOB31_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974648.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            6763..7434
                     /locus_tag="NOB31_002471"
     CDS             6763..7434
                     /locus_tag="NOB31_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HCI0974649.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            7440..8126
                     /locus_tag="NOB31_002472"
     CDS             7440..8126
                     /locus_tag="NOB31_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974650.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            8129..8959
                     /locus_tag="NOB31_002473"
     CDS             8129..8959
                     /locus_tag="NOB31_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HCI0974651.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            8976..9827
                     /locus_tag="NOB31_002474"
     CDS             8976..9827
                     /locus_tag="NOB31_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0974652.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNTELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            9824..10183
                     /locus_tag="NOB31_002475"
     CDS             9824..10183
                     /locus_tag="NOB31_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HCI0974653.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANDWKVKLQER
                     FELMPKFELEGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            10198..10359
                     /locus_tag="NOB31_002476"
     CDS             10198..10359
                     /locus_tag="NOB31_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCI0974654.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            10356..10661
                     /locus_tag="NOB31_002477"
     CDS             10356..10661
                     /locus_tag="NOB31_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974655.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKTR
                     RRMPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
BASE COUNT         3788 a         1715 c         2026 g         3203 t
ORIGIN      
        1 cggtacaggg gtttgttttg tatttgtgcc aaaaatgtgc caaactagtt atcattttta
       61 tataaactat cgaacacagt attgattttt tctttatcct gatcttcaag ctctcgaaca
      121 atatgaagat aagtagacat tgtagtttct aaactgctat gtcctaaacg tttcgatacg
      181 ctaagtatat ttactccttg ataaagtaaa atagatgcat gtgtatgcct tagtccatgc
      241 aaagtaaatt gcttttcaat ccctaattct tttaattttt tgcgcaaata tttgctgacg
      301 gcgtttgatg aaactaatcc attttttaag ttgaaaaaaa caaaattatg agggtttttg
      361 atttcaaaat tctcgaataa ttctttttga ttgattttaa acttttttaa gagatcaatc
      421 gtatgtttat caatggaaat tttcctattt gaagtttcgt tttttgtttt tccccattca
      481 tttaatttat aattccatgt tttattaata gtgatgattt gatcttcgaa atcgatatct
      541 tcccatgtta atcctagaag ttcagcaaat cgcattccag tggcaccagc aactaacacg
      601 agcataggag aagagtactg cgcagaaagg ttttcttcta cgagtttcat taaagattta
      661 aattgatcat aatctaaata tttatcttct tttggcttca atgaatcttt tcctttgatt
      721 actgcttttc tagttggatc aaacggaatt aatccttctt ctacggcatc tttcaacgac
      781 gctctaatat ggttattaaa cttaataacg gtagatttta catggtcttt agcatactta
      841 tttaaaaagc gttgatatcc cactctatct aaatcagaaa tcaataccgc tggcatatat
      901 ttctttatgt tcattaacgt atcttcgtat tttctataag tgataggaga tactgttcct
      961 tctttataaa gttgcatcca atcctcaaag taatctgata ataatagatt tttgcgatcc
     1021 cctttaaggc ctttgttcaa gttatattct aattcgttgg cggcatcttt tgcttcgcct
     1081 tttgtcttaa atcctgattt tcttatcttc gtgtattttc cgtcatcttt tttgtatgaa
     1141 atttcgtatt gccaactatt tccacgtttg actaatcttg ccataattga atctactctc
     1201 tttctctgat acaataggca ctataaagaa gcctactgta taggtttgtt tttcttagaa
     1261 cacgcttgct ttggacggtg ggcgtgtttt ttatttatta tacagttgct ttaaaaatag
     1321 ctgctttttc aaatgatact aaaggagaga agtggatttc tatttctccc ttttggttta
     1381 acgtgaaatg agcagttaca tccatttgtt ttcctggagc aacagatccc attgtatttt
     1441 cgttggcata tgtctctgat tttttgtcat ctggtccata tacttccaca tctgtaccta
     1501 cagggatatc tgaatcgcca tcatttttta cggtataagt aatttttact acttgtgcag
     1561 gttggttttc ttcaaattga tttctttcat cagttagttc tacactattt agtgtatatt
     1621 cagcatcacc aacttttaca gtgtcaccaa tcttatagaa ggtatcgctt ttttcttctt
     1681 tagaagatga agcagaggtt gaagatttag ttactttttc gccaccatta tcacttgctt
     1741 tattactatc tgatccacca tttaaagcag aaccaataat tataattaaa attactgcta
     1801 atacccaaaa ccatactttt ttgtaaaaag gtttactaac tttatacatt tttccgtctt
     1861 gacccataac tttttttgcc atttaaatat tcctcacttc ttgttataat atatttgcga
     1921 tctcagaaat gaggtatgag tccgtgtgcc agcacgggct tttttaatgt tttgctgaaa
     1981 tcggtttttt taataattct tgatgtattc atacatattg ccttgcgtaa gaatattttt
     2041 tcttaaaata gcattggcag acagcataac aagtgtatct gagcttattc tgaatagaat
     2101 aatactccat aaatttttcg agattaaact gagattcatc agtcagttcg ttctcaatat
     2161 agatatttaa taaaattaga atagctattt tatctgcttc tgtttcaaat tttgagtgaa
     2221 aagttgtaga agtatcgtac aaaactgaat attcaaaatg agaagcggtg aaatgcgcaa
     2281 gttcatgaga taaatgaaag gcttctgcag tttcgccata tagattttca ttcaaaaaaa
     2341 tgattctagg cttcggataa tagaagccag gctctttcat ttccatgtaa actactttca
     2401 aattgtattc gctcaacatt tctttcaatt tcaaatacat acaacccatc actccaacta
     2461 ttcattttcc tctaaagctt tagcaattgc aatcgcttta cgcattgtct ccttagatat
     2521 ttcttttcca tcaaaagaaa aaacagtatc gttttctgat aaatccacat gtttaggggt
     2581 ttctttttct tcgcgcccca gaagatagtc tacagagaca tcgaaatagt cagcaatttc
     2641 ttgcaaacgt tctgtagagg ggtttgagtt cttaagtcta tataagacgt ttttaccata
     2701 gcctaggtct tcttcaactt tatttaatga ttttccctgt tttttcgcta actcttttat
     2761 tctctcaaac gttatcatat caatattcct ttcgttcaag aaaaaatatt taactttatt
     2821 tgttaaaatt cgttgactat tttaacaaaa ggtgttaata tcattcttgt aaacaagttt
     2881 aacaactaaa aagacaacaa aaaacactat cgattaataa atgccaaccg ccaagaaagc
     2941 ttttaaaatc aatgtttata tgtcttattt aactatgttc tgattttaac actgtatgtt
     3001 aatttagtca acgcagtttt tttaaaagtt gttaaatttg tttacgaata taaaagaaag
     3061 gagagaagaa tatggaaaaa acagtctcgg caaaaatcga agatttgaaa ttagacatac
     3121 tgaaacaagc aaaagtggcg atggaacacg cggtagataa agaagactct gccatggttg
     3181 cagccatagc agagatttta gctcacgttt agtcatcgtt tttacggtct tctggaagct
     3241 gaccatagat aacagcataa tgaatatcta aataagcttg agcaatttct tttggcgaaa
     3301 ttgattcgcc tttagtagat acttgtgatt cgtgatttag ccatgcaaca actaaatccg
     3361 cagcgatttc atcagttttt ttattcatac ttattcacca ccttatgcat tatttcagta
     3421 gaccacttac tgataagaaa attatatcaa agaaaggaat gaacaaaaat gaacacacca
     3481 caaattttta gttttgaaca acatgaagta agaacgtttc tagaaaatga cattccgtat
     3541 ttcgtagcaa acgatgttgc caaaactttg ggatacaaaa atcccagtaa agccaccaat
     3601 gatcattgta aaaaatcaat tgaaacatgg ggtaacgatt cgttaggtcg tcgtcaaaaa
     3661 ttcaaagtta ttccagaatc agatgtttac cgcttgatta ttaaatcgaa cttaccaagc
     3721 gctgaaaaat ttgaggcctg ggtaatggaa gaagtccttc caacaatcag aaaaacaggt
     3781 agctattcaa acgtacctca aagttttgca caagcattgc gtttagcagc agatttagaa
     3841 gaaaagaacc aattactcga acaacaaatt gccgagtacg aaccaaagat tagctactta
     3901 gatacgattc tttcatcgac agatacggta gctacttctc aaattgcagc tgattacgga
     3961 atgtcggcaa ttgctctaaa caaattgcta aacgagttag gtgttcaaca taaagttagc
     4021 ggacaatgga tactttaccg aaaacatatg aaccaaggat acacaaaatc gcacacaagt
     4081 gagattccga aagccgatgg cggcactaaa gttgtaatga ataccaaatg gacacagaaa
     4141 gggcgagtgt ttatttacaa cttattaatc gcagagggct attaccctca aatggattta
     4201 gaggaaattg gttagaaagg agttttagta tgactgacat tgcagaaatc actcaacgag
     4261 atagagaaaa aatcaaagaa tatgtcgaaa gttcgaagtt cttaacttac accatgcttg
     4321 ctgaaagatt tggaattagc aaaagctact tatctttaat tttaaacggt aaaaagactt
     4381 ctgcagaagc aaatagaatc atagattcga ttattactat gtacgaattg taaagggagg
     4441 aacagctaat gcaatatcta gaagcgaaaa tcccagttcc agaaggctat gtaattatct
     4501 cccaagtgga ttatgaggag ttaaaaaaag ctgatgatac tggtagatgg atgacgttgc
     4561 cagaagtgct agaacggatt aacagaaaat atgattggtt tacttctaga gttttaaaga
     4621 acccaagata tagaaatatt atcgatatcg agaaaaacaa aaatggattt gtctattatc
     4681 cagttgaagg aagagacaca tatctatttt taagaagtaa aacacttgaa tttttagaaa
     4741 caaatttttc ggaaatctta aggaggcaag cggatgggaa aatttaatag agcgctagtg
     4801 ttcagcgcac cgctaatcat ctacgcttta ggactttggg gaagcaggca agcgttgata
     4861 ggaacgattg tttacatggt ttggattttt atggggcttg atgaagctga agctgagtac
     4921 agagcgaaaa agccaaccga gggggctgac taaaaatgaa tagaaaagag aaactagaat
     4981 gtatattact attactcagt ttaattcttt cactaatttc tctattggga agtttgtatt
     5041 tttgatatca acaattttgt ggatttgggt tctatttaga gtaaatatca tttttgtttg
     5101 gtgattaagg agtttattaa aattaatttt ccctacttca aatgcaaggt aacaagatat
     5161 agcactttta ggaggaatat ttagcggtac agcttcagag tatattctat tatcatcgac
     5221 tgatcctcct ttagcaatta atttcttaaa tggagtagct gaccatctgc ggtttaagtt
     5281 agcggatgaa agttctaaat taactaacat agctggttct gttgaatagt tagaaatgat
     5341 tacttttgta taaatcatat ctgcagcgaa gtaagaagca ttaagttcaa cttctagttg
     5401 agggcgcatt ccttttattt ttatccctgt taaaaacgta ctcaatataa aacttattat
     5461 tgacatccat tgaaaaattg ttaagtgaaa aaaattcaaa ataaacacca ccagttttta
     5521 actaaattat accaaaaagg agagaagaaa taatgcaaga attagtaatt ttgaaaaata
     5581 aagaagctgt gactacgagc ttacaagtgg cagaaagctt cgagaaaaaa catcaacatg
     5641 ttttaagaga tattgatgca ctaaaaaaag atgtgtccaa ttttggacag atgtttgtag
     5701 aaggtaatga accagattca tatggcagaa atcgacgagt tttcttcatt agtagagatg
     5761 gatttttctt gctggctatg gggtttacag gaaagaaagc tatctacttc aaacaaaaat
     5821 acattgaagc attcaacgaa atggaagatg ttattcgcaa gaatactgtt cctcaaacaa
     5881 ttgaagatat gatgatctat caattagaag aaatgaaaga tgttaaaaaa gatgtttcca
     5941 tgcttaaaga tactatgcga attagcggac aacaagagtt tgaaattaag caaaaaggaa
     6001 atatgaaagt tatgggagtt ctagggggaa aagaaagccg agcttatgaa gaaatcagca
     6061 aaaaagtatt ctcaaaattt tggtctgaat ttaaacgtac cttttcaatc ccaagatatg
     6121 gcgagttacc tcgtaagaga ttcgatgatg ctgtttcatt tattgaaatg tggttgccag
     6181 aaactgcgat ccgtatggaa attgatcaac tgaacagaca acagagactt tttggtgatg
     6241 acaatgaata gagctgaagc gctaagaata gggacggcaa ttgctaattg ctggtggaaa
     6301 tactataaac caatcatcct aagccaacaa catattgaca agcaaaaagc atggcaacaa
     6361 ataaaaaagt gactccgccg gcaagcaaag agtcacaaag aaaacacatc ataaggagat
     6421 tttagcatat ggaaaaagaa ctttccactc tagatcaata tttgattgat cctgattggg
     6481 gcaagccgaa aattgaggaa acaagtggtc gaaaaatcag acgaaatctt ttgacgaatg
     6541 aagaactagc ttgggatcaa gatgatttag gcaaccatgt aactatttgg gatcatgttt
     6601 atcttatcca tctatcgaag cattcgaata aacctgaata tatttacgtc atcgaagatg
     6661 gcttgattga tgcgctagaa gagtacgaca gagataactt gattgatatc tcttattacg
     6721 gaccaggtaa gaaatacatt gctgaaatgg aggcagaatt tgatgagtga aatcaaaggg
     6781 acaacgaact ttgaaaaact ttttagtcgt aagttaaata aaattctcaa gaaaaaagga
     6841 aattttgatt atttatcttg ggctcacgcg tgggagatta tgaaaaagaa tgatccacag
     6901 gcaacggtaa ctattaatga gtacaaacac tacagggttg tttctggaac tcatcaagac
     6961 tttcttgttg aggaatataa accttttctt atggatgaaa ctgggactta tgtatctgtc
     7021 tcagtaacgg ttaaaggaca cacggaaacc gaattatttc ctgttttaga ttatcgaaac
     7081 caaccagttg ttaaaccaaa tgcaatgcaa atcaataact cattgaagcg atgctttgtg
     7141 aaagcattgg ctctacacgg actgggatta tatgtatttc aaggggaaga tattccaaca
     7201 ccacctagaa tcgatacaaa gaaattaaac atgctagaga cgattctaga agctttcaat
     7261 gagcagatgg gtaaagatat gaccaaaacc ttaatcgaat atgttaatga gcagacagat
     7321 aaattagggc tcttagctga taacgttgaa actattgaac agttaagcta tgagcaatgt
     7381 gccttgatgg agcgagcaat agcagctaag agaaaagaat tagataagaa gtgatatgag
     7441 tgtttaaacc attaatcgat tcatattcag cggttctgaa aaagttcaaa ggaaaagaca
     7501 taagcgcaac catcaatgag gaagtgaaca ttgatcgact aaagacgatg tatgacggct
     7561 acgatggtga tcgagtcatt gaaattcgtt ttattgatcc tagacgtttc accgtacagc
     7621 aacgaaactt catctatgcg ctgataggcg atatttttat cgatacaggc atgccaacgg
     7681 acttctggaa ggaattcttc tactttcgtt ttgaaggtgt cacagggcgc aaaataagcc
     7741 tgaaagacga atcgaataca actgtgagtg atgccaatgt cttagcaaat atcatcttag
     7801 atttcatctt tgaacatcat attcctttca aagaaggcta tgagatttta cctgcgaatc
     7861 aagaatatta cttctacaaa tgcatcacaa aaagagtctg ctgcatctgt ggcaaaacag
     7921 gagctgacat cgatcacttt gacaaagcgc taggaagacg aaagcgcaaa gaagttgatc
     7981 attcagagta cacatttgca gcactctgca gaatccatca cacagagaaa cacaaaatag
     8041 gtgtgatcaa tttcaaaaat aaatatcaaa tcaaagggat caagttaaac caggaaacaa
     8101 ttaaaaagtt aaggatagga ggataaattt ggctgagata agttggatca aacttaaaac
     8161 tactatgttt gacgatgaaa aaatacgatt aatccaagct gttcctgagt cggatgccat
     8221 catcgttata tggattcgat tactagtttt agcaggaaag actaacgacg atggtctgat
     8281 atatatccag aggaacatgc cttataccga agaaatgctt gctacattgt ttggcaaaaa
     8341 cgtaaatacg gttcgcttag cgctaactac attggcaaat ttcaacatga ttgatctaag
     8401 cagtgatgga ctaattgcca tcagtaattg ggaaaaacat caaaatatcg agggtatgga
     8461 taaagtaagg ctaaaaaatg ctgaaagaaa ccgtaaatac agggaaagaa agagacagga
     8521 acgtctcaaa ttggaaaatg acgttagcgt gacgtcacgt gacggtacag ataaagatat
     8581 agaagaagat aaagatatag ataaagaaga aaagaaaggt aagtattctg acgaacactt
     8641 acgccttgct aaaaagttgc aaagtaattt aactgaagat tttccaaaag aaatgaacaa
     8701 agtagatatc gaaaaatggg cagacacaat caggttgatg gaagaaagag ataaagcatc
     8761 tatagaagcg attgagtatg tgatcaattg gctacctaca aatgaatttt ggtttggaaa
     8821 tattagaagt gctaagaaat tgagagaaaa atttgagaag ctcaaattcg aaatcaaagc
     8881 agacaagaag aatcataaaa agcaaagtca aaaactacag tacagcaatc ctagtgaata
     8941 tgacgacttg ccaatttaaa aaggagatgc atcacatgga aagcctagca aatgctatgg
     9001 agaaactaat aagaagagta ttagtgcaaa gcggaaaatg tccagaatgt agcgaacctt
     9061 tgtatagttg gcgagctaaa aataaggatg gttcagaacg ttgtaaacca acatgcatga
     9121 gttgtggtta taaagcgtta cgtgtgaaag aggatataca gaccgaacgg atatataacg
     9181 atagcttaaa agcacgagcg ttgagttttt ttcaaaatgg ttcggtatta acagataaaa
     9241 ctttgtttaa atgcaaaatg gaaaattatc acgtagtgga tcaagaaaca aaaatcgctt
     9301 tagaaaaagc aaaaagctat acgaatgagg ttctgctgaa ccatcctgca catttcattc
     9361 tatcagggaa atcaggaagc ggaaaaagcc acttatcaat ggccacagct tgggaaatac
     9421 ttgagcgctc aaattatgac aagaaaatac tttttataag ctatcaagaa ttattagagc
     9481 aaataaagtt ttcttataac aatactgaac tgagaaaaga aattgaagga tcgcttatag
     9541 ccgatattaa aacaactgat ttggtggttt ttgacgatat tggagctgaa ttaggtagtg
     9601 gggtatcaaa tagtaggcag tttacaaaca acacgttaaa cacgctctta gaagccagac
     9661 agaacaaggc aacgattatc acaacaaact tatctggtcc cgaactaaga gaagcctacg
     9721 gcgaaagaat tgtttctagg atatttaaga attcagaagg ttatgcgctg aaattccaac
     9781 aaacagcaga caagcgcata aaaccagtga aaggtagtat cgcatgaata aataccgtaa
     9841 taagaaaact gttcatcgag gtatcaagtt cgattctatc gcggaagcag agtactacga
     9901 tctagccttg tggcaagcgg aagcgaatga ctggaaagta aagcttcaag aaagatttga
     9961 gctgatgccg aaatttgaac tcgaaggcaa aaagtatcgc aaaatcgagt atattcccga
    10021 cttcacattt tataaaaatg gcaaacttgt aaaagtcgta gatgtcaaag gaatgcagac
    10081 aaaagacttt aagatcaagg cgaaattgtt ttgtcatcaa tatcaagttc cattgatatt
    10141 agctaaaaaa tatcggaata cgttcaagga agagcgtttt taaagaggtg gtccatcatg
    10201 acaacagaag aagtgattca aatgcgtatt cgaagcattc aacgtgaaat tgacgatctg
    10261 gaacgaacaa aggcagtgat ggtcaatgaa acggctagaa aggcaattga tttgcacata
    10321 gagaacttaa gaagggaaat tcgtagattg gaggaatgag cgtggataag aaagcagcaa
    10381 tgaaacgaat catcgaactg acacattctg agaattggca agaagacaaa gaaatagttg
    10441 cagaagtcca aaagctcggt aaatcaatgt ggactgaaaa aaccagacgg agaatgccga
    10501 gaaaaattgc aatctggcac ggtgaccgaa ttctagtaac aggtaccgct gaacagttat
    10561 ctgaaattac tggtctgagc aaaaacatca tctgggatag agctaggagc ttatggattg
    10621 attcaaaagg acgacagttt aggtatgtgg aggagaaata atggatctca ttacacaata
    10681 tagtgatatc atcctcaaga aaatcatgat gaagattcag aaagacaaaa aa
//
LOCUS       DAIGSZ010000082        10341 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.084, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000082 DAIGSZ010000000
VERSION     DAIGSZ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.084"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(644..1624)
                     /locus_tag="NOB31_002478"
     CDS             complement(644..1624)
                     /locus_tag="NOB31_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HCI0974656.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
     gene            complement(1637..2515)
                     /locus_tag="NOB31_002479"
     CDS             complement(1637..2515)
                     /locus_tag="NOB31_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCI0974657.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            complement(2531..3331)
                     /locus_tag="NOB31_002480"
     CDS             complement(2531..3331)
                     /locus_tag="NOB31_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HCI0974658.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
     gene            complement(3606..3755)
                     /locus_tag="NOB31_002481"
     CDS             complement(3606..3755)
                     /locus_tag="NOB31_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974659.1"
                     /translation="MKKKVIPYCPKPRNAFERGLFKYFEGKKGQDHKEENQKKKSKKR
                     SEYIF"
     gene            4723..5049
                     /locus_tag="NOB31_002482"
     CDS             4723..5049
                     /locus_tag="NOB31_002482"
                     /inference="COORDINATES: protein motif:HMM:NF013698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0974660.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            5030..5965
                     /locus_tag="NOB31_002483"
     CDS             5030..5965
                     /locus_tag="NOB31_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI0974661.1"
                     /translation="MQKWICDLFMCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSE
                     KNRALNCLTVSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEE
                     IQAAVEGAISVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGL
                     DTQPITAIAILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKP
                     LLVQIANALLRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSA
                     KGYLEPKPAKEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            6594..6845
                     /locus_tag="NOB31_002484"
     CDS             6594..6845
                     /locus_tag="NOB31_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HCI0974662.1"
                     /translation="MKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESLD
                     SFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
     gene            7387..7545
                     /locus_tag="NOB31_002485"
     CDS             7387..7545
                     /locus_tag="NOB31_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0974663.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            7617..8843
                     /locus_tag="NOB31_002486"
     CDS             7617..8843
                     /locus_tag="NOB31_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0974664.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGIASEKYQKVFPTRQLAIKA
                     EREMKKKIETVLREENANSLELKGKIKFKDFYESKWLPRYELGQTTRSNRAPSNVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILCYIEFNRTTKIIQCITAPKKMALEEKRIREGNQALSSEELTDWIEAVNNDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFNKNTVRLKYALDKYQRKTHTKGWKDTV
                     IQAPEVVMTLLREWKSAQAEQLLKLKIIQTPDQYLFTYSKPSGEVNCPVHADYLNYRI
                     NAIKKRHPELAQLSPHKLRHTYATIAREGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKSVFEAFQKGLNKCD"
     gene            complement(8932..9324)
                     /gene="rpsI"
                     /locus_tag="NOB31_002487"
     CDS             complement(8932..9324)
                     /gene="rpsI"
                     /locus_tag="NOB31_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCI0974665.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(9340..9783)
                     /gene="rplM"
                     /locus_tag="NOB31_002488"
     CDS             complement(9340..9783)
                     /gene="rplM"
                     /locus_tag="NOB31_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HCI0974666.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(10111..>10341)
                     /locus_tag="NOB31_002489"
     CDS             complement(10111..>10341)
                     /locus_tag="NOB31_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0974667.1"
                     /translation="DYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFYHSE
                     SGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
BASE COUNT         3231 a         1997 c         1743 g         3370 t
ORIGIN      
        1 taaaaaatat gcggcgcaca gaacgcgccg catatcggac taagttttat tcaaatttgt
       61 cttcgccaac acaatttgac gaagagcctt ttctttcagg aagacttcgg taatttttag
      121 gagttctacc tattctttta accgtttatt ctctttttct aagcgtgtaa tttcatttct
      181 gcgaatggat ttcatgactt cctctaccga gaaaagtacg ttatccatat ttttcaactt
      241 cttgaactca tcaatacacg ctattagagc gagcttctag ctatagacta acttctttaa
      301 cagaaaaccc ttcttccgtt accagtttta cagcggtaat tttaaatatt tcatcaaatg
      361 aacgtcttgg cataatccag atcttcgctt tctcttaatt tggtgtcaat tttagtataa
      421 cccgtccaac ttatttttta actaagtgcc cggtttttct tgacaactcc acccaaaagt
      481 tagatttttt ggtctaagtt ttagggtcgc ttcattacta gaattcaaca agagatgttt
      541 tttattttat ttaaattatg gggtcagttt ccatttgatt acaaacttct ttgttttctt
      601 tttttaaacg caataataaa ggttttaatt tcagcctttt taattagaaa atcaattttc
      661 ccaaattatt ttctttagct ttcttaacga tttctgtcgc aactaccaca tctaatacag
      721 ccgaaccaac tgttttgaag atcgtgattt gttctccact tgtccgaccg atcaattctt
      781 cattgatcag ttggcctagt tccccatgat agctgtctct ttgaatatac ccatcttgca
      841 gcggtgaaat gaagtcccca gcttctttta gaacaccgtc catggtatca aaaataacaa
      901 catctgcggc tttgattatt tctcgtggaa tttcacacat ttccggtgtg taagcaccga
      961 ctccattgat gtgcgcacct tttttgaccc actcagcaga gaatgtcgca cgttttgaag
     1021 tggtcacact tgtaatgatg tctgctcctt caacgcattc ttgactggtt tttgttgggc
     1081 gcatcgttac agaaaattgt tgcatcattt tttcagcaaa ttggctggca cgctcaaaat
     1141 caatatcaaa aatccgaact tcttctaatt tacgaacggt caacattgct tctaattgtg
     1201 actgtgcttg tccgccggtt ccaatcagcg cgccaatttt agcatcttct cttgcaagaa
     1261 gttctgttgc tgctccttga acagcgcctg ttcttaattg tgtcaaataa gtaccatcca
     1321 aacaagcgga taccataccc gtttctggat ccaatacgat catcgttgct ggtacacttg
     1381 gtaagttttt cttgatgttt tcaggataca cggaaacgat tttgacacct agcgcgcctt
     1441 cgccaccttc tacataagca ggcatatata agctttgtcc gttgcttttt ggcacatcga
     1501 tattggtgcg aagaggcaca cttgcctttc ctgctgaata caatgacagt gcttttttgt
     1561 ccgcatcgat ggcttctctc attgaaaaac ttttgataat atcttctttt ttaagaaata
     1621 acatttgaat cgctccttaa ttagctgctg taactttttt taattgactg cccaacatcg
     1681 tatatgcact gtatagtaag accaaaatca cgatccattt caggatatag gtatctaaag
     1741 atttgactag gaatacagcg accaataccc ccaatacacc gaaggttgaa gtaaaaagtg
     1801 tgatttttct gctgtattca ttaaatttaa tgaattgaac actgccgatc ggtactgaga
     1861 aggtacaagc ccccatcata ataggaaagg ctgcaactgg attcaagcct agcaagtaga
     1921 cagttaccat cgttaacgca taagaaccaa tgccgatatt gttcaatgca ccatagacaa
     1981 agagtaaaaa tcctgccaag attaattttc cgccatacaa ttcactggct gttccgtttg
     2041 atggaatcca gttcatttgt cctgcaaaaa tcaacaatgc agcaatgacc aatcctatgc
     2101 cgacaaacag tttgatcgtt ttctctggta acttcacgac aaatcttggt cctaaatatg
     2161 caccgataat ttggcagata atacaaacag ctagtgtctt gatccctacg ttgatggcag
     2221 tgatgtaaga caatgccatg acggctaccg gtactacaca ttgggtattc aacgttccgg
     2281 gtagtttttt catgctgacc catttcaact ttggataaag gacggttccg atagcaaagt
     2341 cggaaacgcc aaatgttgaa agaaagaaga tgataaatga cgtgaagggc aacagacgca
     2401 tatcccctgg ttcttctttg aaattttgtt tgtttttgaa aaggtctctt agaaagtaaa
     2461 taataaaata tagattgatt gcgacaatta gtgtcagcaa aatattccga atcataaaaa
     2521 attcctccta ctagtaaatc tttctgattc cctcaaagcc ctcaccatat tttgctttaa
     2581 gttcttcagg agattctgca atcactttta gtgtatatgc atcatgtttg acatattctt
     2641 ttgctagatt gaccatggcg tggttttttg tccaagtgac atcggttgat tgcagttctt
     2701 cgttaatggt accaaacacg acttcttgct catcggcgac gatgttgatc catcttgctc
     2761 caaagtcagc aagtttgtct gtttcaaaac catgaatata atacttttct aagggaagat
     2821 catattcatg ggtagaactg aataaaatca gtacaaactt atcaactctt ttttcagctt
     2881 gctgcaatgc ctttagtagt gaatccgtga aattctcatg ccaaacttga atgagcaaac
     2941 tttcttttgc gtttttcacc aaatgctcta ctttatccag aacatactcg ataccatcaa
     3001 ctttccacag catttcttct tcatcttttt ctttgatcat ccctagattc ttggtaagaa
     3061 aagaaagatc atttttaaca cttttttcta atttctctaa aaactcattt gccgagatgg
     3121 catgataaag tttaggttct gatttattaa cgacaatcaa attctttttt aatagttttt
     3181 ccaaaatatt atatactttc gagcgtggca cacctgagat tttacttact tcatatcctg
     3241 taagattacc tttttctaat agtgtggtat acactcttgt ctccatctct gaaaaatcat
     3301 attttttcat gatttgaata atcgtttcca ttgattaatc ctcactttat ttttagtagc
     3361 tactacggta acaactataa attctttttg attatctgtc aagagttagt tcaataacac
     3421 acatataata attagcttaa aaacaatctt tttattaaaa agaaacatta taatatgaat
     3481 gtttgtgaaa aaataataca acttagtcat tctttacaac gatttataga aaaacaacct
     3541 ctttaaatat aaaaggtacg ggttactgat tacttgtaaa tctttacgtt ccagttttat
     3601 tctttctaaa aaatatactc acttcttttc ttagacttct ttttttgatt ctcctcttta
     3661 tggtcttgtc cttttttgcc ttcaaaatat ttaaataaac ccctttcaaa agcatttcta
     3721 ggttttggac aataaggaat gacttttttc ttcatataaa tacctcattt aactatttga
     3781 tatcatcaca ttatcaaaaa aaataggttt tttattaaaa ctatcttgac ctttcgggag
     3841 atttcactgt gatttatttt tattcccata cttttttcgt tggtcacttt cgtataccta
     3901 atctaagcga tcatcggcga cggtgctttt acaacgaatg gcaggacaaa acaaggggcg
     3961 gaaaaacttt tttgcctatt tcataaaaaa ctttttccta cagcaatccc ttgttttgtc
     4021 ctaccacacg ttgtgaaccc aaagcacgcc gacgaacgct tagctatacg aaaatgacct
     4081 ccaaaaacaa aaaagtgagg tgaatagaaa caaaaagaaa ttgaaatctc ccaaaatgtc
     4141 gtccgcctcg gagacaactt gctgctgaaa atggttggtt aattcattta agtattaaat
     4201 aagataaatc atcaaattaa tcggaaaaat agcatgattg gccttatcaa aaataaactg
     4261 taaaaactta tatttctatg agtggtggaa caatgctaat accaaattaa tttatcgatt
     4321 acccacctgc acaaaccaaa gatagcatta ttaggaaacg aatcaatcag cgaatccagc
     4381 attataatga ggatactaaa aataaagttt tcataattat aaatccgcct tcctacgaaa
     4441 ggcaccaatg aggtgatgaa aaccttagag cgctttcttt ctttttttat tccgtgttac
     4501 cctttccttg caggtccctg gtacactaca gaacccgagg aggtgagtgg cggggctgta
     4561 tagcggcaac cccgcataat tatatggtgt cggtcatccg ttaaggcatc aatgaatggc
     4621 gcaaacccgt agcccgtaaa cttatctctt ccgaagttga ctcgatttcg ccggatgacc
     4681 agtccctacc aaacctgtac tattttttta caggaggttg ctatgttcaa aatctttcgt
     4741 aaaaattgtt gtggcttgga tgtccacaaa acgtggatct atgcgtgtat cggaatcaca
     4801 gatgcgaatg gtcgtacagt gtataagcaa gctcgcttct cttcctttac aaaaggtctc
     4861 aatgaattag ctgaatggct tgctaaatac aactgtaagg atgtgtgttt ggaatcttcc
     4921 ggtaaatttt ggattcctgt ttttaatatt cttgaaaaaa cttgttttgt cacactggct
     4981 catccgaagt acaccaaacc ccagaaagga aataaaacag atcgcaaaga tgcaaaaatg
     5041 gatttgtgat ctctttatgt gcgacatgat caaacccagt tttattcctg gtcttgaaat
     5101 ccgccagctt cgtgatctaa tgcgttatcg gacgaaactg accaacatga aaacaagtga
     5161 aaagaatcgt gctttaaact gcttaaccgt ttctaatctg aaactagatg atgtttttag
     5221 tgatgtgttc ggaaaatcat ccacttctat catccaatac ttgttagaac atcccggtga
     5281 atcatttgat gttcgaccat ttatccatgc ccgttgtaaa actcccgttg aagaaatcca
     5341 agcggcagtt gagggggcga tttctgtacc tcaagcgatt aagcttcgcc aatgcctcaa
     5401 ccatattaac gagattgaga agcatcgaga agagatcaat ctagagattc aagctcttgc
     5461 agaacccttc tcccctgttt tggaactact tcgtaccata ccgggcttag acactcagcc
     5521 aataacagcg attgcgattc tttcagaaat aggaccggat atgtccgtgt ttccaacttc
     5581 gaaacacttt atttcttggg ctggatgctg tccaagaaac gatcgcagtg cccgacgaac
     5641 aaaatcaaca cgtatctctc gtgcagggca gtcgttgaaa ccgctacttg tacagattgc
     5701 caatgctctt ctcagatcca aagaacatcc agaatttaaa aatcgctatc gtagaatcaa
     5761 agcgaatcgt ggacacaaga aagctatcat tgctatttgt aagatgctcc tgaccgctat
     5821 ctggaatgtc ttatcaaagg tggaacccta ttctgctaaa ggatatctgg agccaaaacc
     5881 tgcgaaagaa gagaaagttc tgacgcaatc ccaagctctg gaccttttaa gaaaacgcgg
     5941 atataccatt atagatagtg cttaaaccaa agttacgttg attcttccta aatagactcg
     6001 ttgtcttcca tttcaaaaat tttgaaaacg gtaggcttat ttagtgtacc gttcttcagg
     6061 tatcttcaaa tagatttatt ttcaaactta tttcctttct tcttttactc tcctatagct
     6121 tagcatttaa gtgggcactc gtgtcacctt gctagatagc tatgaatgcc gtaataagcc
     6181 tcctagtata taggcagact gccaattata actgattcaa tccacattat gataaaatcc
     6241 accttttcgt ttcatatgtg ttgaaatatc acatatgtca aaagtgcacg agtcttttca
     6301 ttcagtgctt tgtaaatact caaaattatt ccttttcact ttaaaaaaaa gataattagt
     6361 acaaaatcag aaatgaggaa agtattagga tggactagaa aggagttgtt gaatttgttg
     6421 caacagattg gtcatttatc aattaaaaat taggtgaagt tttattcatc actgcagctg
     6481 ctgtttccca gagaataaaa cgtctagaag aaactggtca gttactgtat tatcaagcag
     6541 caattgacta cgaacaagct tgattactaa ccaaagcgtt tatccacctg ttgattaaat
     6601 caaatcaaaa atcaggtttt tatacgttca taaaagcaat ctccagtgta ctcgaatgtg
     6661 actgtatcat aggtccttat tcgatgttaa tcaaaatggg gtttccttct accgaatcat
     6721 tggacagttt tatcaatgat ttatcaaagt ttggacgaac caacacccaa atcgttttct
     6781 cgactcttgt ttccttaatg gtttatcagt tctggaatgt ttatcatgcg cttttattaa
     6841 aatagaaaag agcttttttc atgcgacaaa gcagtgatca tttattggca catgcaatct
     6901 ttgtggatcc attttttgaa aatacgatat ttagttttga cccaaaaatc tttaaatacg
     6961 tatttgataa tttatcttaa caaccagata attttattca gcaccgtatt atctatattg
     7021 aattctcgga atcaagataa atttttttcc gtttttgttt cttttttaat cttcttcttg
     7081 ttattaatag tgattaggat gatattccta tattgatctt tgataattag atataatttt
     7141 tgaataacgt tccctgctat tcgagctaga aatacaagta cgccatgacc tagttagcga
     7201 caactactta gagatttctt ttgttctggg acaacaaaat gccatgacaa tagcagtaaa
     7261 taatgatact tccgtaaggc tcgccgtaaa ctggggagag gtgaaattcc tatgtgctta
     7321 cccaaagcgg ttcaaaaatt ttaaactatt attttaggag atgattttat aaaatcgaaa
     7381 gcctacttga ataaaaaaca agcctgtgaa tttctaggaa ttgataataa tactttagat
     7441 aagtggattc gtgtatataa ttttccagta ataaaaattg atggcgtagt tcgctttgac
     7501 gtagaggata tcaaagattt catgaataca ttcaaaaaaa attgaaattt tcttctcgtc
     7561 acatatacta taaatagcga aatgtactgc cttacttttt aaaggagtga ggaagtttgc
     7621 ctacaaagct ttcaaatggg aaatataaaa ctaatctgag gtatccaaaa aaattcagag
     7681 aaatcactgg aattgcatca gagaagtatc aaaaagtatt tccaactagg caattagcta
     7741 ttaaggccga aagggaaatg aaaaagaaga ttgaaacagt tttaagagag gagaatgcaa
     7801 actcactaga attgaaagga aaaataaaat ttaaagattt ttatgaatca aaatggcttc
     7861 ctagatatga actaggtcaa actactaggt caaacagggc tccaagtaat gtaacaatta
     7921 gtaatactaa ggatatattc cgattgcaca tccttccaat gtttggtgaa tatgcaatga
     7981 attatctgaa ttcaaatact gagataatat cagatgaatt aacaaagaaa tcgaaagaat
     8041 acgcaaatat aaaaattatc aaaggctatg ttcgctctat gtttgatatt gccgaaatac
     8101 tatgttatat cgaattcaac cgaactacca aaattattca atgtattacc gcgcctaaga
     8161 aaatggcttt agaagaaaaa aggataaggg aagggaatca agcattatca tcagaagagc
     8221 tgactgattg gatagaagca gtaaacaatg acttaaataa tcacttgctt acacttcacg
     8281 attacacact tttcatgctt accttatatc taggtgatag aaaaagtgag acttatgctc
     8341 tgcaatggaa atatattgat tttaataaaa atacggttcg tctcaaatat gctttagata
     8401 aatatcaaag aaagacacat acaaaaggtt ggaaagacac cgttattcag gcaccagaag
     8461 ttgtgatgac attattaaga gaatggaaat cagctcaggc tgaacaattg ttgaaactaa
     8521 aaattataca aacacctgac cagtacctct ttacctattc caaaccttct ggagaagtaa
     8581 attgtcctgt tcacgctgac tacttaaact atcgaatcaa tgcaataaaa aaaaggcatc
     8641 ctgaattggc tcaattatct ccacacaaac ttcgtcatac ctatgcaact atagctaggg
     8701 aaggtggagc aaatatgaat caaatctcta atgctttaac gcactcggat atttctacta
     8761 caaaaatata cgtgaacaca cctgacgtag ttgataaatc tgtttttgaa gcatttcaaa
     8821 aaggattgaa taagtgtgat taacatgtgt tctcaaatgt gttcttatta taaaaaaaga
     8881 cactttccaa ataattgaaa agtgtcctga aatattgata taaaaagaat attaacgttt
     8941 tgagaattgt gaagctttac gagctttttt aagacctggt tttttacgtt cgaccatacg
     9001 tgcgtcacga gtaagtaagc cagcacgttt aagagctaaa cggaagtcag gatcaacttc
     9061 tagcaatgca cgagcgatac catgacggat agctcctgat tgtccagcgt atcctccgcc
     9121 gtttacgtta acaaatacgt catatgcgcc ttttgtttca gtaacagcga aaggttgatt
     9181 gattacttca cgcaagtcag catgtggaat gtattcttca acatcttttt tatttacagt
     9241 aattttgcca gttcctggta ctagacgtac gcgagcaact gcgtttttac gacggcctgt
     9301 gccgatatat tgaacttgtg ccaatgaaat tccctcctat tagattaagt ttgtgatgtc
     9361 taaaacttct ggttgttgtg ctgcatgtgg atgttctgct ccaccgtata cgttcaattt
     9421 tgtaaattgt ttgcggccta aagtgttttt aggaagcata ccttttacag aagtttcgat
     9481 caaacgacga gaatttttag cacgcaattc gccagcagtg attgatttca atcctcctgg
     9541 gtagttgctg tgacggtaat aaattttgtc agtcgctttt ttacctgtta atttcacttt
     9601 gtctgcattg atgacgatga cgaaatcgcc agtatccaaa tgaggtgtga aagttggttt
     9661 atttttacca cgtagtacag atgcaacaac tgttgaaaga cgtcccaatg gaacatcagt
     9721 tgcgtctact acataccatt tacgttctac ttcgcctggt ttggccatat atgttgtacg
     9781 cacgttattt tcctccaatt taagttctga tgtttgacat acacttcgag tttccggggc
     9841 tctttgtggg gcaaacaata ccatttaaca tattacccgc taatctagtc aatgtcaacg
     9901 tttttctgct tgattgaaaa atttaaatga aattttatat ctaattttca attatccgca
     9961 taaacactat acattcaagc attttgaagt atagaaaaac actcatctta ccacgaattt
    10021 accacgattg aatgagcctt gatatgaccg taaaactact aagggagata gcacgaaact
    10081 gtgtatctcc cgattttttt atacagttga ttacttcact ccgatttcaa atttcaatat
    10141 tgctttcatc atgtctgtat gaatttctcc ttttagttct tcatcaacct gcataatgat
    10201 tttaccactt tcagagtggt aaaaaggacg caagcataat ttagaaatat aaccgtcata
    10261 aaacttcaaa atctctttaa ctgccatttc atctccgctt gacgctttgc aaatcaattc
    10321 aaaagaggga tagccataat c
//
LOCUS       DAIGSZ010000083        10160 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.085, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000083 DAIGSZ010000000
VERSION     DAIGSZ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.085"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..91
                     /locus_tag="NOB31_002490"
     CDS             <1..91
                     /locus_tag="NOB31_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0974668.1"
                     /translation="NIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            356..835
                     /locus_tag="NOB31_002491"
     CDS             356..835
                     /locus_tag="NOB31_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974669.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            868..3096
                     /locus_tag="NOB31_002492"
     CDS             868..3096
                     /locus_tag="NOB31_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0974670.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            3225..4868
                     /locus_tag="NOB31_002493"
     CDS             3225..4868
                     /locus_tag="NOB31_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCI0974671.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(4941..5486)
                     /locus_tag="NOB31_002494"
     CDS             complement(4941..5486)
                     /locus_tag="NOB31_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HCI0974672.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(5509..5994)
                     /locus_tag="NOB31_002495"
     CDS             complement(5509..5994)
                     /locus_tag="NOB31_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCI0974673.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(5984..6796)
                     /locus_tag="NOB31_002496"
     CDS             complement(5984..6796)
                     /locus_tag="NOB31_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HCI0974674.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(6935..8467)
                     /locus_tag="NOB31_002497"
     CDS             complement(6935..8467)
                     /locus_tag="NOB31_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HCI0974675.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            complement(8576..9607)
                     /locus_tag="NOB31_002498"
     CDS             complement(8576..9607)
                     /locus_tag="NOB31_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0974676.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT         3395 a         1866 c         1945 g         2954 t
ORIGIN      
        1 taatattcct agaaaatcac tggattatcg aacacctttg gaagtatttt tgagttacgt
       61 aagtattgat gatctgtcta acttaatttg acaattaaga atacaaaaaa gatgttggtg
      121 aagttcacca acatcaaaaa gtatagagcc aaaatattcc aacatcatct tggactttct
      181 acatgttact aatgagcgtg taaaagaacg agatggtgtt tttatttcta tcaatgaagc
      241 tctttttctt tgcaatcctc acttcaatcc tctataatgt cgcatatagt ttagtaaatg
      301 agtaaactac taatttactt atttactaaa aataaaagga tgaggagtta aaataatgga
      361 aataccaaca aatttaaaac ataaaccagt aatcgttgta gaagactatg ataaagttga
      421 tggaagaaat gcattaaata tggatgcaaa agggctttca ctgggccttg ctcagtggaa
      481 tgatcgtgga aaagtcgata tctcaggcaa ggtatggcga catactggag aaaaatggtc
      541 acgacagtcg gaagaattac caatcacacg tattttagat ttagcgatct tagctgcgca
      601 aggaagttta tacttccaag atgcttatcg ttatgaaaaa ttttatgatc cagaaaatcc
      661 agtcgtagac atcattggat tacaagggaa ccgaatgacg gtagaagtag ataccaaaaa
      721 tccaaagatc gatgaagaca tcattttgta ttacgataca ctacaaaaag acggagaact
      781 gattggggaa cgattccgta ttttaaaacg tcttttagat gagctaggat attaatagac
      841 agagatgatc aaaaggggaa gagaagcatg gagaatttct cactaacaga aaaccgaacc
      901 ttttcacggc tagaaaagca aatgatctgg aagaaaccga aaagccatcg gacaagtgca
      961 gaagaatggc ggatcgcctc cgaaatcaaa gggaattggc aagatcctga aatgaaaatc
     1021 agtaacgtac ttttggaagg agatgccggg tcggggaaga cacaattagc caaagcacta
     1081 tctgctgatc tgcaacttcc ctatacaaaa gtgacctgtt ttgcagatat ggacaaatca
     1141 gatgttttcg gagccttatt acctgtagta gattctaata aggaacaaga ccaagaatta
     1201 ctagaagcta tttaccaaac agatacactt gaagctgtac tgacactgat ccagaaccat
     1261 tacggcattg atcctttttc tgctaaagaa aaattagcag agctagttca aaggatcgaa
     1321 gctgattatc cagatgcaat ccattacagc tattaccctt ctgaaatcgt tcgagcgatt
     1381 gaaaaaggct atttattaga gattcaagag ccgactgtca tccgagatgc ctctgttctt
     1441 gtggcactta actcagcgct cgaaccaaat gggatgttga atttaccgac aggaatcatt
     1501 cgtcgccatc cagattgcgt cattgtgatc actacaaatc gaaattacca aggaaatcgc
     1561 ccattaaatg aatctttaag agatcggatg caacatgcgg aaaaaatgga tcttcctgcc
     1621 ttagaagtca tggcagaacg tgcgatggcg aaaactatga tccaaaaaca agaacttctc
     1681 ttaaagatgg cagagattat ccgtttgttg gatgaaactg caaaagctaa cgccatcaaa
     1741 ggtgtagcag gaatgcgttc ttatttttat tgggcaaata cctataagca aggacaagat
     1801 ttactccagt cgatttatcc aaaagttttg tataaattat ccactgattc agatgaattg
     1861 gcaattcttg aacaagcttt gtctgacagt ggattgctac tggaacttca ggacatattg
     1921 agaaaagaaa aatggggtca tcctcaatct gagcatacaa aagaaagaac cattagcgcc
     1981 gaagaagcaa atgaacgaaa catcactgaa aatgctgaag aaattctgcg cttagatgaa
     2041 aagaaatcgt tgtctgctga agaaccaaat gagggagaag agaaacaaga agaaacaata
     2101 gaaaaaaacg agattcctcc tcaaatgcaa aaagaacgca gtagcgatat cgaaggaaaa
     2161 aatcaaaaag aacaacaaac aggagatgat tctcaagaaa tgtctgcttc tgacatggaa
     2221 gcacatgata aggaaatcaa gaagcaactg aataaagaag cgcgacaaat catgaaggaa
     2281 acgattcatg aaaaagaagg tctcatcgtt caccgaccag ctttccaagg aaaaacgccg
     2341 gaagcacgtg agctacacat gcaagtaatg ccaatagtag aatcacttag ccggcaaatt
     2401 ttagagttac tggataatga acaaacagag acgtaccaaa aaggaaaata cgaaggtcag
     2461 cggttcaatg caagcaaagt agcatatggt gatttgagaa attttgacaa aaagaacccg
     2521 ccacatgagc aaccttcttt agcggtagct gtacggatcg atgaatctgg gtcaatgata
     2581 cgggatgatc ggatcgaagc ggcaaaaaaa gcagcgattg ccattgccga attttctaag
     2641 aaagtcgata tcccattgtt gatttacgga gatacagcag accgttcgtc aagagaaaag
     2701 acttctttgt tttcttataa agaatttgaa gacggatttc aatggttaaa tgaaaaatta
     2761 gtcactatga aaccaaggca aaacaatcgt gatggtgctg cacttcgttt agcagcagaa
     2821 aaattaaaca gacaatccgc aacaaccaaa ctgttgctta atattagtga cggtcagcca
     2881 aaagcgttgc cggattatac aggcaaaaaa gcaaaagaag atatccagtc tgttttgaaa
     2941 gaatatgaac gtcaaggaat cctatttgtc tccgcagcta ttggccaaga caaagaagaa
     3001 atcaagtcga tctacggtga aagtcgtttt gtagatatta ctgacttgaa tgaatttccc
     3061 aagcaaatga ttcaactgat tgcccgctat ctatgataaa ataaagctca acgaacgcac
     3121 ttagcagatt cgttgagctt ttcgtttcta gttaccggta acaaggatac ttctaaaata
     3181 gaatcggtta taatcaagag ggaccgttaa aggagtgaaa cgatatgata caagaacaaa
     3241 aatggtggaa agaagcagta ggctatcaaa tctatcctgc tagtttcaaa gatagcaatg
     3301 gcgatggtca aggagacatc aatgggatcc gtgaaaaact taattatttg aaagatcttg
     3361 gtatcggctt tatctggatc aatccgatct atcaatctcc atttgtcgat aatggttatg
     3421 acgtaagtga ctatcaagat atagaagaga gattcggaac gatggaagat tttgatttat
     3481 tgctaaaaga agcacatgaa ttagggatca aagtgattat ggatcttgtc atcaaccata
     3541 gttcggatca gcatcaatgg tttgaagaat cgaaaaaatc taaagaaagc ccgtatcgcg
     3601 attattacat ttgggtcgac ggggtagatg gcaaagaacc gaataattgg acatcgattt
     3661 tcggcggttc tgcttgggag tattctcatg aaactggaca gtattatctg catgtttttg
     3721 caaaagaaca accagactta aattgggaaa gcgagaaatt gaaagaagaa ctattcaata
     3781 tgatccgatg gtggttggat aaagggatag atggatttcg tttagatgcg atttctcatg
     3841 taaaaaaaga tgaatattca gtaaaagcca cagagaaccc tttctcaccc tttcaaaatg
     3901 tctcaggaat cgaagaacat ttgaccgatt tgaaacatgt ttttgaagag tacgatatca
     3961 tgactgtcgg agaagcaagt ggtgtcactg cagaagaagg accacaatgg gtagggaaag
     4021 acggttattt cgatatgata ttcgaatttg atcatatcca tatctggcag caagaaaaag
     4081 aagggcaatt agatgtcctt aaattgaaac atgcattaag cgcttggcaa acttcattgg
     4141 atggtatcgg atggaacgct ttatatatgg aaaaccatga tgttcctcgt gccgtttcag
     4201 tgtttggaga tactcgtccc gatttttggg ctatgtctgc aaaagcaatc gctatgatgt
     4261 atttcttttt gcaaggtacg ccatttattt atcaaggaca ggaaatcgga atgacgaata
     4321 tgccctttga atcgatcgat caagttgatg cagtagattc gaaaagactt tataaaaggc
     4381 tgcttgcgga aggtaagaca agagaagaag cattggatat cattcgtgaa acaacgagag
     4441 acaacagcag gacacccatg caatggactt cggaacaata tgctggtttt tctacacatg
     4501 aaccttggct gatcactaat ccaaatacca aaacgatcaa tgtagaacaa caagaatatg
     4561 aaccagagtc ggtcctgcaa ttctataaga acatgatccg cattagacaa accaataaag
     4621 gtctgatata cggttcttat aaagaatatc ttcatgaaca tccacaactt tatgtctatg
     4681 aaagatattt agaagatgaa caatatctta ttatggtaaa cttaacagaa tcacttgctg
     4741 actatgaact tccaaaagaa gcagatcagt cctggacatt actcttgtca aattcctcta
     4801 gcggagaatt tgaagctaaa ggcatactag caccttatga agctcggtta tataaaacaa
     4861 acaagtaaaa cttcctcgtt aaagttcatt agttggactt tgcgaggaag tttttcagat
     4921 tgctctgtca attactcatt tcaataattc gctctaggac caccgatata tttaggacga
     4981 gagcgaaggg ctgtcacgtg agcttgtcca agggttttca aacgaggtct gacaggtact
     5041 tggacatgct tgatatgcat accgattgat gtgtcaccga tatcgatacc ggcttgtcca
     5101 actacgtgtt ccacttcgac aggatcattg aactggtcaa aagcagcaac agaacaagca
     5161 cctccagcat gtagtgcagg aacaacagag acaatttcga aattttttgc ttctgccact
     5221 gttcgttcta ctactaatgc tcggttcaaa tgttcacaac cttggacagc tagcgcaatt
     5281 tctttaggat ccaacaactc ttttaacgta cggatgatcc attgaccaac ttccgcactg
     5341 gaattttttc caatatgtcc tccaacgact tcgcttgtgc tgcatcctaa aacaaaaaga
     5401 tcaccttttt tcaagtgtgc ctcagccaat atgtcattaa ctatttcagt caattggtct
     5461 tttaattctt tttctgacaa cttcattttc taaaaccttc tttttcaatt aatattgctt
     5521 ccgtgcttga atacgttgaa gacttgcagt tataggaaag gcaagtccca ttccaatcag
     5581 attttggaag atgtttcctg gtatagaagc cactccagcc ggccaatcat ataaaatcca
     5641 accggcgata ccatagccga tgatcataac taagcttcct aataaaagcc ctaatcccca
     5701 catacgagta gaagatttgc tgaaagaacc agcaacatat ccttgtaacc cgtggatcac
     5761 taatgaaaaa actgcccact gcggatatcc tgaaatcaaa tcgatcaata gaccactgga
     5821 agcaccaaca actaatccac ccgttggacc ataaagaaaa gcagcggtat agatcccggc
     5881 ctcgcataat gtcacaaatc cattcgtagc cggtacaggg atcaaaattg ttaatgaaag
     5941 ggcaactgtc aacgcaatca gcatagcata gatcgttaat tgcttagttt tcatttctca
     6001 ttcctccttt ttgaataccg ccagaccaga cacttccggt atgatcgttc atcagcacgc
     6061 cattagaaat acaatgggca acaaattttt tactttctgc tactgctttg gtaaaatctg
     6121 cccctaacac aagattcgct gttattgcag aagaaaaggc acaaccggcc ccgtttactg
     6181 ttgtagtgtc gattttttta tgagaaaata cctcataatg atcaattgaa tagagaagat
     6241 ccacagcttc atctccagcc atccttgtgc cgcctttgat cacaatgttt tttgttcctg
     6301 aagcagtgag ttctttagcg agatggatca tttctgttaa cgaagaggga agagcttgac
     6361 cagaaagtaa agcagcttct gccaaattag gcgtaatcat cgtaacaagt ggaaaaagtt
     6421 cttcgatgag ctgcgaaata tacaattgat tgatcacagc ttcagtttct ttgaatgcca
     6481 aaacagggtc taaaatgatt gggatatttt gttttgtttt tatgaagtct cgaacaacca
     6541 tgattgcttc acttgaattc aataacccaa ttttgatacc atctaatgaa gtcattttat
     6601 caatcgaaac taactgtcgt ttaagcaatt ccaaagatat agattccagc ataaatcgct
     6661 cattaatatc tagtgcccct atagaagtca aggcgcttag tccgaataga ccaaaattct
     6721 caaaagtttt taaatctgtt tggattcctc caccagcaaa tggatcagaa ccgccaattg
     6781 tcaagattct tttcataaca ttttcctcca tgaataagag tataacgaaa ttttcaaaaa
     6841 agaaaaacag ccaattggca tatttttatc tcatccaatt taaaaaaaca aaaagaaaag
     6901 aaagaccaaa atggatcttt ctttccttaa atagttagga cttttgtgat tttaattctt
     6961 tctcgatttg aagccgttgc actttcattg tagctgttcg cgggattgca tcaaaatcac
     7021 ggatgatagg gacgttcaag cgaggaagtt catggacttg ctcccaccat cgattccaat
     7081 ccatttcttt atcaggagct aaagcaataa tcggttgtgg agaatgattt ttatccctta
     7141 caatcactac ttctgccaaa aaatctaacg aatctaataa aaagtcttca atagctaatg
     7201 tactattgat cgtttcgatc aaatccactt gccgatcttt caaaaatagg tggccatgct
     7261 tatccataaa accgtaatct ccgctatccc accaatcgcc ataaacattt tcctggaacc
     7321 gtgcatcttc cttgtaataa gtcaaagccc gtcctttaga cagtaattgt atatgaccat
     7381 ctgtgttttc aggtaggaca ttcccaactg aatctgtaat ccgagcgctt gtcatgtctt
     7441 ccagtccaac gcccatatct cttgcatcac ttgttttcaa actctctagt gtatgagcct
     7501 taagaatcat tggtccgcat tcactttggc catatacttg aagaaatacc gcatcctgtg
     7561 ccatcgacgt tcgcaaaaat gtcttcattg tctggttgtt tatagcatca aaagtggagt
     7621 gatagtatcg gatacccgaa aaagcttctg gatgctcctt agcagtaaaa cgccactgaa
     7681 caaagttatt cggatgggtc tctagtgcaa ttggccggtg agcttccaac atatgaacaa
     7741 cttttgaact ttgtgcgttt gctaaaggca tcataggaaa tcccatggac atcaaagaag
     7801 agataccaat attgaatctg gaatgcactg gagagatgtg aaaagcgatt aatttctttt
     7861 ccgaaatttt tgtgaaaact gttttttgcc atttcgtccg ccatcccata gaatgagcag
     7921 aatgacaaat aagtttaggg ataccagttg taccagaagt atgggtcata taagaaattt
     7981 catttttgtc taaaaatgat tgagaaacag acaaagcagg ttgttccatt aaataaagaa
     8041 taggaatctg ttttgatttt gttccatttg aaatttctct cactcgcttt tttgtctcat
     8101 catcaaataa aatgaaaggg tcttctaaac gatcgataaa tacttccatt gttgttgttg
     8161 gtagatgata agaagtcatg acaggcactg caccaaggta agacacagaa acagctagaa
     8221 ggtatgtgtc aaaagcggaa ctcttataaa taataacttt gtctccggat ttcactccaa
     8281 gatgagccaa ttgataagcc cgtttcaaca cactttcgca gcattttttg taagttgttt
     8341 caagtcctaa ttctgggaaa gctgaaagtg gctcatcaaa gataatcggg gtctcggaaa
     8401 agttagctgc agcttcttga aaattcgtaa ataagttcaa aggggaatac gttatggtct
     8461 ccatcattca cactccatta tcttttgtta agtaatatac aaattcaaga taatcgtaac
     8521 ataatccttt atataataac atagtttatt gtgaaaaaaa gatcatacat ttgttttata
     8581 tggaagaaac ccgaacgaat gccgctaatt cgtgataaga aaaatcaacc atcttttccc
     8641 agatatcttg aaaagaatgg gatgagaggt atcgattacc acataaataa tttaccgcgt
     8701 cagcatcatc taaatatagt tctgcataat aacgatatgt ttttctgcat agttctggcg
     8761 atacgttttt atatactgta attttgctca aaatttggcg aatagtccga ggagaaattt
     8821 gctgatcatg tgaggaacga aaaacaaaag aattttcgtc cgtattttgt gctgttaact
     8881 taaaatagtt ctccagaaat ggcatcgctt cttttggtat tggtacttta ttcagtctgt
     8941 tttcttttct attcagatta agaatctgct tggtcaaaga tacatcttta cgtttaagtt
     9001 ctactacttc atggatcttt aatccgcaat acagaagaat ggcagtaatt gcaaggttcc
     9061 tcggtctatt cttttcttca aagctagctt ctctgcttgt ttgaaagcct tcaatcggga
     9121 taaacaaatg ctcaaaatct ttgaaaagtt ctgcatcgat atatcgcgga gctgctttgg
     9181 ttgtttccgg taaacttgta cccaaaagag aaatctcttc ttcaatcagt cctttttgat
     9241 acaaaaatcg taaaaaatga tttaatgaat attgcttcct tgaaatcccg taatagctat
     9301 tttcaaacaa ttgctccgtt tcttggttcg ctgtagtttg gaacgaacga gtatgtcgat
     9361 agattttagc taagaaattc tgataatctt gtttttctaa atggataatc agctgatcat
     9421 ccacttcttc agaaaatact tttctcaaat aatcagtaaa cagatgaaaa tcttttgcgt
     9481 attcatagcg actgcctaat gaaagggaag aacgattttc ttctaaaaac tgttgaaaga
     9541 cggaagggag caagtgtgta cgttgcttta acttttcttg cagttgtttt ctagttttgc
     9601 tgtccattac aaattccctc caatagtgtt cattttctat attttaccgc atttcatcaa
     9661 atgaagatag acagtttgtc ttgatcttag gaagcaaatt tttaactaag tactagctaa
     9721 aagatatgaa gtaagaagat acatttttag ttattttatt agtgcagtca ttcttttgat
     9781 cttttaattg atttatcctc tttttagcta tgtggttact tcatgagcaa tgaaatggat
     9841 ttggttcgtt ctaatggcag gaggctcttt cttttatttc cgaaaaatta gaaaacattt
     9901 tttcagaatc gattggctct ccatttattc aataatggtt tgtctaacga tattgttggg
     9961 ataattctta aagaagtatt agaaatagtt ggtacttcat tactttacat gaagatttat
    10021 tctatggtag gagcaattat attgagaatt aatccttttt tatataagtt gtttgcttat
    10081 tgatggattg gataaattaa accatcacaa cgagtggaaa ttatatgaaa tttttcataa
    10141 aaattcatat agaaacaaat
//
LOCUS       DAIGSZ010000084         9899 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.086, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000084 DAIGSZ010000000
VERSION     DAIGSZ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9899
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.086"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="NOB31_002499"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="NOB31_002499"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCI0974677.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="NOB31_002500"
     CDS             complement(2261..2512)
                     /locus_tag="NOB31_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HCI0974678.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="NOB31_002501"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="NOB31_002501"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HCI0974679.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="NOB31_002502"
     CDS             3462..3680
                     /locus_tag="NOB31_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974680.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="NOB31_002503"
     CDS             complement(3969..4481)
                     /locus_tag="NOB31_002503"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HCI0974681.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="NOB31_002504"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="NOB31_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HCI0974682.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7377)
                     /locus_tag="NOB31_002505"
     CDS             complement(6934..7377)
                     /locus_tag="NOB31_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HCI0974683.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="NOB31_002506"
     CDS             complement(7378..8166)
                     /locus_tag="NOB31_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0974684.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /locus_tag="NOB31_002507"
     CDS             complement(8163..9104)
                     /locus_tag="NOB31_002507"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HCI0974685.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="NOB31_002508"
     CDS             complement(9281..9868)
                     /locus_tag="NOB31_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HCI0974686.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
BASE COUNT         2703 a         2214 c         1746 g         3236 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttat
//
LOCUS       DAIGSZ010000085         9888 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.087, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000085 DAIGSZ010000000
VERSION     DAIGSZ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.087"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(109..2229)
                     /locus_tag="NOB31_002509"
     CDS             complement(109..2229)
                     /locus_tag="NOB31_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI0974687.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="NOB31_002510"
     CDS             2459..3637
                     /locus_tag="NOB31_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HCI0974688.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="NOB31_002511"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="NOB31_002511"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HCI0974689.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="NOB31_002512"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="NOB31_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HCI0974690.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="NOB31_002513"
     CDS             complement(4990..6243)
                     /locus_tag="NOB31_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0974691.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="NOB31_002514"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="NOB31_002514"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HCI0974692.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="NOB31_002515"
     CDS             7821..9167
                     /locus_tag="NOB31_002515"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HCI0974693.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="NOB31_002516"
     CDS             complement(9475..9861)
                     /locus_tag="NOB31_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI0974694.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3149 a         1800 c         2025 g         2914 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt gtttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttatta
//
LOCUS       DAIGSZ010000086         9874 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.088, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000086 DAIGSZ010000000
VERSION     DAIGSZ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.088"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(22..267)
                     /locus_tag="NOB31_002517"
     CDS             complement(22..267)
                     /locus_tag="NOB31_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HCI0974695.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(382..960)
                     /locus_tag="NOB31_002518"
     CDS             complement(382..960)
                     /locus_tag="NOB31_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0974696.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1037..1567)
                     /locus_tag="NOB31_002519"
     CDS             complement(1037..1567)
                     /locus_tag="NOB31_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HCI0974697.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1571..2431)
                     /gene="rlmB"
                     /locus_tag="NOB31_002520"
     CDS             complement(1571..2431)
                     /gene="rlmB"
                     /locus_tag="NOB31_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HCI0974698.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2424..2819)
                     /locus_tag="NOB31_002521"
     CDS             complement(2424..2819)
                     /locus_tag="NOB31_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HCI0974699.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2816..4228)
                     /locus_tag="NOB31_002522"
     CDS             complement(2816..4228)
                     /locus_tag="NOB31_002522"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HCI0974700.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4225..4761)
                     /gene="cysE"
                     /locus_tag="NOB31_002523"
     CDS             complement(4225..4761)
                     /gene="cysE"
                     /locus_tag="NOB31_002523"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HCI0974701.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4847..5086)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5083..6543)
                     /locus_tag="NOB31_002524"
     CDS             complement(5083..6543)
                     /locus_tag="NOB31_002524"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HCI0974702.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6713..7870)
                     /locus_tag="NOB31_002525"
     CDS             complement(6713..7870)
                     /locus_tag="NOB31_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HCI0974703.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7904..9274)
                     /gene="radA"
                     /locus_tag="NOB31_002526"
     CDS             complement(7904..9274)
                     /gene="radA"
                     /locus_tag="NOB31_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HCI0974704.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9337..9864)
                     /locus_tag="NOB31_002527"
     CDS             complement(9337..9864)
                     /locus_tag="NOB31_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HCI0974705.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2509 a         2214 c         1784 g         3367 t
ORIGIN      
        1 aatctcaggc tcgtttgctt tttaaactgc ttcagttaaa aattcgatct caactgtccg
       61 agtaagtaca tctgaatagc tgtaagatac tcgttcaaaa gaattttctt caggatccaa
      121 atcaacaacg aatactgaag gataggtttc tgttaaaacg ccgcggcgtt ctgtttgacg
      181 ctttcttcct gtctgagcaa ccaacatgat tgggctgccg atacgacctt ctaaatcttt
      241 cttgattgaa gctaaagttg ttggcataca gttcacctct actatcaact ataccacata
      301 tttttaaaat tttcaagttt accataaaaa aaaaagaaat gcaataaaaa taaataagaa
      361 gctcattaag atttttctaa attattcctc attataaaat ttcaagtgtt tttttatttt
      421 gagttttact ctcccgtaag cgctcattac ttgcttgtga tccattgcta aacattcagc
      481 catgtctaca aaatcaacgc cttgcatata ataatgaaaa attttagctt ctatttttga
      541 aaactggatt tcgcaatttt cgattgcttc ttttaataaa agatgctgaa tcgctaaagg
      601 ttcttgcaat gtgatctctg ctaaaaagtc tggtccttct gtctctattt tttggtcgat
      661 tgagacttca tctttttgat cacgacgctt cagcgcgttc tgcttcctca acagagaata
      721 gatttgattg cttataatgc ttttataata acttccaaag ctaacacctt tgcttttttc
      781 gtaagttctc aatgcctgat ataaagcgat ccttgcttct tgttcccaat cctcagaaac
      841 ataatttctt aaataatagg tgtttttcaa acgtagtaaa agtggaaaat atttttgata
      901 cagggcagca aatgcttctt cgtcaccatt acgtgcagcg cgcaataact cctcagacat
      961 aaaataattc ctccataaat tcgtttatgg aggaatctta tcatcaatga ttcatcgaac
     1021 tgattagaac gatatgttat ttattttttc tcattaaatc gtccaatttt tgggacaatt
     1081 tttttaactg ctcttcattc catggagaat tacgtcggaa atcaataaaa tgcatatctt
     1141 tattttcttg ggctattgtt ttttccgttt tttttatcgt cttatataat tcataagcag
     1201 aagttcgtaa tgctccttgg gaaaagatca tccactgttc tgctaaatcg cttgtcgcca
     1261 ctgtcacttg tgtcaaacgg tcattcagct gaccagcgat tctctcgata taactgtcag
     1321 ccgtttcgtc ttctttcgta aaaacaacat ccaactggta tttcttataa ttttgttgga
     1381 tgcccggaac tagttgggca tcgaagacaa cgatgacttc cattccttca tatttcgcat
     1441 aatttgataa acgatgtaaa agagcttctc ttgcatccgc cattttgtcc tgctttttaa
     1501 gctggacaag ttccggccac gaaccaatca tgttgtagcc gtctacaatc aacagctgtt
     1561 ttttcatggt ctactccccc tgacgttggg aaaaagcctg atacataagc aaaccagcag
     1621 caacactggc atttaagctc tggacgtgcc cggtcatcgg gatcgtcagc aattcatcca
     1681 tttctttttt caatcctgga ctcattcctt tgccttcatt accaatgact aaagcaattg
     1741 atcctttggc attccatttt tggaagtttg tgccggtcat atctgtgcca aatacccaaa
     1801 atcctgtttc tttgagctgt tgcacagctt gtaccaaatt cgtcacgcgt gcaacaggga
     1861 catgttcgac tgccccagtg gaagtctttg ttacgatagg tgtgattcca actgctcggt
     1921 gttttggtat gatcacacca tcgacgccac ttgcgtctgc tgtccgtaaa atcgacccaa
     1981 aattgtgtgg atcttcgatg ctatccaaaa tcaaaaagaa ggggtcttct tttttctctt
     2041 ttgttcgttc aatcagttgg tcaagggata aatattcata aggtgtaatc gcaagaacga
     2101 ctccttgatg cacgccgtga tcgctcaaag tttctaattt ttgtttagga acccatttga
     2161 ctggcacagc ttgttcacgt gcgatttctt tcagttcttc tactttttct cctcgtgaat
     2221 cttcttgaag aaagagttta ttccctcgcc cttgttgtag cgcttctact gcggcatggt
     2281 gcccaaagac gaaattatct tctaatgctt cttcattttg atcagaaact gactgatttc
     2341 gtccagtttg ctttttattt gaatatctat tttgtttttt gtcttcaaat ccacgtttcg
     2401 attgatgttt gtttgttctt tctttaccca tttttttcac caactttctg aatacaccag
     2461 cggatcaatt cttccatccg ctcggtttgt tttgtcaaat gcagatagcc catgagcgct
     2521 tcgaaccctg ttgcgacccg atacgtcgta acatcagcat tttttgcgct cgtatggctt
     2581 ttagcatttc ttcctctgcg ataataaagt tcttcttctt ctgtcaaaag atgttcttcc
     2641 agcatttgct gaatcaaaaa ggcttgtgca ttcgcagaaa cataattcgt tgccgcacga
     2701 tgcagcttat tgggttttgt ttctccttga tcaatcaggt ggtcacgaac atagatttcg
     2761 taaatcgcat ctccaacata agccaaggct aaaccgttca attgtgtgta atctctcatg
     2821 cttctcttct ccatcgggtt ccttgcggtg tatcttctaa taagatccct ttttctttca
     2881 acaaatcacg aatttcgtcg cttcggacaa aatcacgatt gcttcttgct tgatttcgtt
     2941 cttcgatcaa ttgttcaatc tcttcatcta ataactcttc tgctgtaaat aaaataccga
     3001 agatcgaaag ccattgcgag aataaagctt ctccttgtgc caagacagcg gcagaaactt
     3061 tcggctggtc tagataagtg ttcagccact tagcaagctc atagaccact gtgatcccat
     3121 ttgctgcatt aaaatcatcg tccatttctt cgatgaatcg ctgttctaaa ttttctaaca
     3181 aagcgatttt atccgcatca tctgccaaat tctctgaggc agtttcttgg cggaatttca
     3241 aattgtcaaa cgtattcttc agtcgttgta aattggtggc tgcttctttc atcgtcgttt
     3301 cactgtagcg gatcggacga cggtattgtg tggtcgccat gaagaaacgc aagacttgtg
     3361 gatcaacgtt tttgatcatt tcatgtacag tgatgaaatt ccctagagat ttactcattt
     3421 tttcatcgtc ttcgccaatc gttacatagc cattgtgcat ccagtaatta gcgaattttt
     3481 tccctgtttt cgcttcactt tgtgcgattt cattttcatg atgaggaaat tctaaatctt
     3541 gcccgccacc atggatatcg atcgtttctc ctaaatgttt tgttgccata acggaacatt
     3601 caatatgcca accgggacgt cctttgcccc atggtgaatc ccaagaaatc tcgccaggtt
     3661 ttgcttgttt ccataaagcg aaatctaatg ggtcttcttt ttgctgctgt tcttcccctg
     3721 tacgctgact tgctccgact tccagttcat cgatggattg gtcacttaat ttcccataat
     3781 tttcaaattt acgggtacgg taatacacat cacctgaaga ttcataagca tagccttttt
     3841 caaccaacac ttgaataaat gctaaaatat ctggcatatg atccatgact cttggatgca
     3901 gtgtagcagg ctcgacattc aacgctttcg tatcttcttc aaatgctcgg atgaaacgat
     3961 cagcaacttc tggtgctgta atacctaatt cgtttgctgt acggatgatt ttatcgtcta
     4021 catccgtgaa attcgatacg aaatcgactt tatagcctcg atattcaaaa tagcgtcgaa
     4081 ttgtatcgaa agcaatggtg ctacgagcat ttccgatatg gatataatta tacacagtcg
     4141 gtccgcagac atacataccg acatgtccct tttgtatagg gatgaattct tctttttttc
     4201 tggtcaatgt attgtagatt tttatcattc tgatctcctc actttttctc ctttgattcg
     4261 aacgactttt gctggtactc ctaccgctgt agcgtcgtct ggaacatctt tcaacacaac
     4321 ggcacctgca ccgattttgg cgttttttcc gatcgttacc ggtcctaata tctgcgcatt
     4381 cgcagagagc atggctcctt gtttaacagt tgggtgtctt ttacccgttt cttttcctgt
     4441 gccgcctaat gttacgccat ggaataaaat cacatcgtcc tcgatttctg cggtttcgcc
     4501 aatgacgatt cccattccat ggtcgatgaa cacgccagtt ccaatcgttg ctcctggatg
     4561 gatctcaaca ccagttagga aacgccagaa ttgagcattg atcttcgcca ataaaaagag
     4621 ccggtgctga tataaaaaat gagagaaacg atgccaaaac aaggcatgaa aaccagggta
     4681 tgtcaaaacg atctcagctg tcgaacgtgc agccggatcg tttctctttg ctgcatcaat
     4741 cgctcgggta aaccaactca tgactttcca ctcctttcgt aagaatttta tgtaggaaat
     4801 catcttctta taaagaaaag aagcgccttt taaataagtt tccttatcaa aagacgcttt
     4861 ccgcgtggtt ccacttttct tcataatcaa tgattatctc tgacagctaa cgcctgttat
     4921 acgttcttgg ctactttgtt tcctataaaa cagtttttcc tgttttctgt gtttcgccaa
     4981 gaccactccc agaggcattt cggcaaccat tcattgatac cttgcaccac ccggtatctc
     5041 tcttgtaatg atcagctgct tacttttttc tgttcatcgt gtttagttca gtacttgatt
     5101 taaatgtgct aatgattttt cacgaccaag caattcgatc gtttcaggca attctggacc
     5161 atgcatttgt cctgatacag ctacacggat tggcatgaaa agattttttc cttttacgcc
     5221 agtttctttt tgaacagctt tgatggcagc tttgacagtt ggagcatcta ctacttccat
     5281 ttgttctagc tgtgctttga atgcgtggag aacagtagga actgtttcac cagcaagtac
     5341 ttcttttgct gcttcattca atacaggatg ttcattgaaa aatagcgtag acagatcaac
     5401 gatttctgca gcatagctca tttgaggttg atacaggcta acgatcttct tcacccattc
     5461 gattgtcttt tcatctgggt tttctgctac acgtccatca gcgattagat aaggcagaca
     5521 catgtcagta aatgcatcta gatccattgc tttgatgtaa tggttgttta cccattgcag
     5581 ttttttcgca tcgaaagctg cgggtgattt acttaggcgt tttggatcga acattttgat
     5641 caattcttgg tgttcgaaga tttcgtcttc gcccacaggt gaccagccca ataatgcaat
     5701 aaagttgaac attgcatctg gtagatagcc taattcgcga tattgttcga taaattgcaa
     5761 gattgattcg tcacgtttgc ttagtttttt acctgtttca ctgttgatga tcaatgtcat
     5821 atgtccgaag gttggtggtg tccagccaaa tgcttcatag atcatcagtt gttttggtgt
     5881 attggcaata tggtcatctc cacgtaaaac gtgagtgatt ttcatcaaat gatcatcgac
     5941 cgcaacagca aaattataag ttggcatacc atcgcgtttt tgtatgacaa agtcgccacc
     6001 gatattatcg gattcgaacg aaatagcgcc tttcaccata tctgtaaatg cgtattctgt
     6061 attgcgaggc acacggaaac gtacaacaga ttctagacct tgtgcttctt tttctgcttg
     6121 ttcttcaggt gtcaagttcg cacatgttcc tgcgtaatga ggcatttctc ctcttgcgcg
     6181 ttgtgcttcc cgttctgctt ctaattcttc ttctgtgcaa tagcatttgt atgctcgatt
     6241 gctagcaagc agctgatcaa tcagcggttg atagatttct ttacgttcag attgacggta
     6301 agggccgtat tctccaggat tttcaggaga ttcatcccaa ttcattccca accaagcaag
     6361 gttttccaac tggctttttt cgccatcttc gatattacgt ttttggtcag tatcctcaat
     6421 acgaataata aagtctccat cattgtggcg ggcaaacaaa taattgaata atgcagttct
     6481 tgcatttcca atatgcaggt gcccagttgg acttggtgca tagcgtacgc gtactttcgt
     6541 cattttcttc ctcttctttc aaactagact ttgactaaca gcaaaaattc cgtcagttac
     6601 ggcttctcaa atatcattta tttaaagcca ctcagcacaa attttacctt ttctaaggta
     6661 aatagtaaag ccaactggtt gaatttcctt accagttggc tgaatttctt ttttattttg
     6721 attgtttagt ctttttctct gtctcttttt tattgtcgat tcctcgtcct gcatgtgcag
     6781 gtttagcaaa gatcatgcgt ccagcagctg tttgaagggc acttgttaca acgacttcga
     6841 tacgttcatt catgtaatgc tgtccatctt ctacgacaac catcgtgccg tcatcaaggt
     6901 aggctactcc ttgttggcgt tctgtcccgg cttttactac tagaacattc atcgtttcac
     6961 cagggatgac gactggtttt acggcatttg ccaacgcatt gatattaaga acaggtacat
     7021 tttggaattc agagacttta ttcaagttat agtcattggt tacaatgaca ccatctaaaa
     7081 gcttagccaa tttgatcaat ttgctgtcta cttcactgat atcttcaaag tctccatcgt
     7141 acatttcgac agatataccc tcttcttttt gcaaggcatt taggatatct aatccgcgac
     7201 gaccacgcac acgtttcaaa ctatcccctg agtccgcgat gtattgtagt tcgtaaagaa
     7261 caaaattagg gatcatcaag gttccttcta agaatccagt ctttgtaata tcataaatcc
     7321 gaccgtcaat gatcacgctt gtatccaaga ttttatattt atggaaattt tctcctgatt
     7381 ttcgttctaa cagttgactc tcaacttgac tagctgtttc ttgctcgatt tttttgcttc
     7441 gtgaaccaaa aactttcttc cattcttcga ttcgtgtcgt tcccattctc aatcccagat
     7501 agcctaagat gatcatcagt aaaatcggca atacactatt gacgaatgga atttccatat
     7561 tgtaaagagg ggtcgagatc acaacaccta aagtcaatcc gatgatcgca ccgatcgcac
     7621 cgaagagaag ataagtcaag ctgacctcac ttagtttttg ttctacttgt ttgataatag
     7681 ctgagatatg tttggccaac agcaaagata ataaaaagaa aataagtgcg cctaacaggc
     7741 tgttggtaaa tgtattattc agccatccgt ttgactgttg accgattgcc tgccaagctg
     7801 agggtaaaaa tgaaataccc aagcttgcgc cgacaatgat catcagcaaa gtaatgacac
     7861 gtttttgcat cgtttttcct ccgtttcgac aatcatttat tagttagcgg aacacacgct
     7921 tcaacgtttc agccaaagtt gctactccaa ctatctcgat tccttttggc gcttcccagt
     7981 tacctaagtt gtttttaggt aggtatactt ttgtgaagcc gagtttttgg acttctttga
     8041 ctcgttgttc aatatgactg acacgtctga tttctccagt cagtccaatt tcaccgatga
     8101 aacattccgt tggctgtgtt cctttttctt tatagcttga agcaatactg acagcgatag
     8161 ctaaatcaat cgctggttca tttaatttta ccccacctgc agcttttaag taagcatctt
     8221 gattctgaag aagcaaccca gctctttttt ccagcactgc catgatcaga gatacccgat
     8281 tgaaatcaag acctgttgtt gttcgtttgg catttccgaa catagtaggt gtgactaatg
     8341 cttggatctc taccaaaatt ggacgtgtcc cttccattgc cacaacgata gcagagccag
     8401 ttgcaccgtc taggcgttct tctaagaaaa tctgtgaagg attagcgact tcttccaatc
     8461 catgctcatg catttcaaaa atcccaatct cattcgttga gccaaatcgg ttttttactg
     8521 ctcgcaaaat ccgaaaacta tgatgttgtt caccttcaaa atataacacc gtatccacca
     8581 tatgttctaa cattcttggg ccggcgatcg agccttcttt ggtaacatga ccgacgataa
     8641 aaatggctat cccatttgtt ttagcgattt tgagtagttc tgcagtggtt tctcttactt
     8701 ggctgacact tcctgccaca cttgtgatgt ctggctgcgt catcgtttgg atggaatcaa
     8761 tgataacata atcaggggag atatgttcga tggcacgact gatttcgttc atatctgttt
     8821 cagcgtatag ataaaattct gtgttgatac ttccgaggcg ttccgcgcgt aattttatct
     8881 gctctgcgct ttcttcgccg gatacatata agacttttcc gcctatggct gctaattgct
     8941 gagaaacttg taacagcaaa gtggatttcc cgatacctgg atcgccacca atcaagacca
     9001 tagaccctgg caccacacct ccgcctaaca cacggttcag ttcttctaat tttgttttga
     9061 tccgaggttc ttttttaggg acgacgtctg cgatttttgt tggttttgct ttttctcctg
     9121 tcaaacttgt ccgagttctg cggtccgttg tatcttgttc gatttcttcg accatcgtat
     9181 tccattttcc gcaatttggg cagcgtccca agaacttagg cgacacatac ccgcaatttt
     9241 ggcaaacaaa ttgtactttt gatttttttg ccattgtacc gcctcctttt atcctaatca
     9301 tgagacatta aatcaagctt aagtatcttt aacgttttat ttactggaag aaccaaatcc
     9361 gccttgacgt tgagcagtcg tttgatcttg atctgctttt aaaaacggca aaaagatccc
     9421 ttggccgata cgctcgcctt ttttgatcac tacatccttg aaaccaaagt tggtgaattg
     9481 gaacatgata tggccttcat ttgcctcatt attgtaataa tcactgtcaa tcacacctac
     9541 tccgtttgtc aacactaaaa accgcttcaa cggattgctt gaacggttag caagctgcaa
     9601 aaattcatct tctcccatgt aagctttgat tccagtaggc acgagggttg gtttcaattg
     9661 tttttcattt tctgatacat cttttttcaa tccatctgcg actgtttcca accccttttt
     9721 ccagcctgct ttccagatac ttggaatcac gacctcttct gctgcttcaa aatcatagcc
     9781 agcagcatga tgtgtagcgc gctgcggtag attgatattt tgatctttat atttagaaat
     9841 aacttcaaat cctctttttc tcaccggttt tcct
//
LOCUS       DAIGSZ010000087         9664 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.090, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000087 DAIGSZ010000000
VERSION     DAIGSZ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.090"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..650)
                     /locus_tag="NOB31_002528"
     CDS             complement(<1..650)
                     /locus_tag="NOB31_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI0974706.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIG"
     gene            975..1391
                     /locus_tag="NOB31_002529"
     CDS             975..1391
                     /locus_tag="NOB31_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCI0974707.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            1388..1858
                     /locus_tag="NOB31_002530"
     CDS             1388..1858
                     /locus_tag="NOB31_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0974708.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            1872..2645
                     /locus_tag="NOB31_002531"
     CDS             1872..2645
                     /locus_tag="NOB31_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0974709.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            2659..3471
                     /locus_tag="NOB31_002532"
     CDS             2659..3471
                     /locus_tag="NOB31_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCI0974710.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            3525..4490
                     /locus_tag="NOB31_002533"
     CDS             3525..4490
                     /locus_tag="NOB31_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0974711.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            4606..7329
                     /locus_tag="NOB31_002534"
     CDS             4606..7329
                     /locus_tag="NOB31_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCI0974712.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            7342..7974
                     /locus_tag="NOB31_002535"
     CDS             7342..7974
                     /locus_tag="NOB31_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCI0974713.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            8873..>9664
                     /locus_tag="NOB31_002536"
     CDS             8873..>9664
                     /locus_tag="NOB31_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0974714.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLY"
BASE COUNT         3260 a         1477 c         1884 g         3043 t
ORIGIN      
        1 ccaatcatat ggaagccacc gattaggtat tttatgggtt tagtcggaaa tgtttcaaga
       61 gcaatttcca tcatatcgat aatgccatga tgactacagc cagtaaagac aatcagaccg
      121 tcttcttgct caattacgac caataattca tctgaaaaat catcataaac aaatttatca
      181 tccatctttt tgtataaatt cttggtggtc gagtttgctt tgcctagggg gatgatatgg
      241 aagctcggag caagttctgt tttcgttttt attgtatgta aattctcatg cattttaagg
      301 atttcatttt taggaatacc aacatacaga aacgtggtta aaatctttaa ataatggggt
      361 aaagttacac cttcagctgt ataaataggg gcgtttcctg attttaaata tcttaacccg
      421 ccggtgtggt cagaatgacc gtgtgaaata atcactgcct ccagatcatt caaagtttcc
      481 cccattttag tcgcattata gactaatttt ttattagcgc cagcatcgaa gagatatttc
      541 ttccctgagt agttaattaa gagagataac ccatgtccac ttttaaagtt caaatttatt
      601 cttgagtttt caaataaaac cttgatttcc actataacat ctcctttcac atgaacgtgt
      661 attcatatat tgtagcacat taagttctat tttttgttgt aattaccgaa aaaaatatta
      721 atggacgctt tttacgcttt atttcgtatg tggaagaaaa tttcttagga tgtggcgggg
      781 gattggggca aagctaaatt ccaattacag tgatcattta attagacacc tttaaatacc
      841 cacactttca tcaacactat aatttaggga aagaaaagtg ttggcatgat atagaaaaac
      901 ctttaattaa cagcgtttcc taaaattggc acgcatcttg cttatagaaa agcgtaagga
      961 taggaggaat gaaaatggca actataattc ttgccagcca tggggaattt gctcaaggat
     1021 taaagcaaac agctacaatg attattggag atagtgtacc aattcatgcc ttgtcagcat
     1081 ttagagatga agatgaatct attttggtac aaataaaaaa acttttagcc acaatagata
     1141 tagaagaaac ctacatttta actgatattc taggtggtag tgtgaataat gatatgctca
     1201 ctattattaa agagtatgag ggattgcaat taattactgg aatgaactta cctttagtta
     1261 tttctattgc aacctataat ggaaaaattg gggaaagtga gctagaaaag cttattaaag
     1321 agagtcaaca atcagtgatt gattgtagaa aattattagt agaacaactt actggaggag
     1381 atgacctatg attaagttag tacgtattga ccatcgtttg ttgcacggac aggtagtatt
     1441 ttcttggagt aaatcattaa atatcaatcg tattattatt gccaataaag aggcagcgaa
     1501 tgatgaattc aaaaaaatgt ctttgaattt atctaaaccg actggcatta aattaacaat
     1561 tttttcagtt gaacagttac tagaaaaaat gcctaaaatc gaaacactta acgaaaatat
     1621 catgcttatt tttggtaata caaaagaaat tcgtcaattt tgtgaagcct atcctaaagt
     1681 acaagaaatc aactatggag ggataatcaa aaaagaaggt tccaagcaat ttagtaatgc
     1741 cattttcttg aatgaatctg agcaagaaga tgccaaaaaa ttaaaagctc ttggcattaa
     1801 acaatttatt caacaggtac caacttctaa aaaagaagat ttgaatacaa tgttataaag
     1861 gaggaatgaa aatgctcgtt cagtcaattg gtttagggtt aatcggtgtt ttttgtattt
     1921 tagactcaag gcttttagga agaatgaatt ttgaacgacc gttgattgtc agtacgcttg
     1981 ttggtttggt acttggagac atggaaaaag gattaattgt tggagcctct ttggaattga
     2041 tgtccttagg attagtaaat atcggagctg ctgcaccacc tgatatgaat atggcatcaa
     2101 ttattgctac agcctttgcc attttatcaa atgcgaatgc agaagcagca ttaacgattg
     2161 ccattccaat ttcagtgtta ggtcaaatac taggtatctt aatgcggacg attttgtcaa
     2221 atttgactca cgttgcggat cgctttatcg aacaagggaa atttagccaa gcaaggagaa
     2281 ttcatatact ttatggctcg ggattatatg ctctcatgta ttttattcct atttttctag
     2341 caatttattt tggaacgaat cttgtttctc agattgttga tgcgattcct gagtggctaa
     2401 caaatggctt aacggttgca agtaaaattt taccagcata tgggtttgcg ttgttattac
     2461 aaacgatgtt aacgaaaaaa atggtgccat ttttattact tggattttta attactgctt
     2521 attctggatt gggaatcatt ggtattgcag ccttcgcatg tattgttgcg tttgtcatgg
     2581 ttcaagttca aggtaaaaac tcaaatggta accaaaatga gccagatcca ttagatgact
     2641 tataaggagg tagattaagt gaaagagaaa gatcaaaatg catggaaata tcggcagttc
     2701 ttatggcgtt catgggcaat tcaagcctca tggaactatg aacgacaaat gaacatgggt
     2761 tttatgtacg gaattgcacc aattctagat aacatttaca agaatccaga agatgaagca
     2821 atgaagaaag aagcttacga gcggcatatg atgtactaca actgtacccc tcaaacaagt
     2881 gcatttgtgt tagggttaac tgcttctatg gaggagcaat actacgaaga ccaagaaaac
     2941 tttaatccgg aatcaatcag tgcagtgaag acttctctga tgggaccgct atctggtgtt
     3001 ggtgattctt tctttcaagg aacgattcgg gtattagcct ttggactagg aattaattta
     3061 gcccaacaag gtagtatttt aggtccaatt ctagcaatgt taatttcctt tgtaccttcc
     3121 tttttagtta cttactatgg tgggaaaatt ggctataaca tggggaataa atacttgtct
     3181 aaactgtatc aagaaggttt gatggataaa gtaatgtatg tttgctccat tgtggggttg
     3241 atggtcattg gttcgatgat tgccagcatg atcgggatta caacaccaat tcaaatgggt
     3301 aaagcttttg tcttacaaga tgtattagat agtattatgc cacaattttt accattagga
     3361 ttaaccttct tcatgtactg gttattgcag aaaaaggtca aaacaggatg gatgttggca
     3421 atctgtttag tcggaggaat tatttttagt ttgttaggta tcttacaata agggaataac
     3481 caataaattt ggttgaataa tataaataag gaggaattca attgatgaat tcaaaagaaa
     3541 ttgttaaaga aatcgtagcg aaaaaagagg taaaatcaat cgtatttgtt ggctgtggcg
     3601 cttcaaaagc ggacctttat cctgcaaagt attttctaga ccaaaatgcg aagcagttac
     3661 ggattagtca ttacacagcc agcgaattta actatgcaac accagcatct gtagatgagt
     3721 caactgtcgt tatttcagct tctttaggag gtacgactcc agaaacagtt gaagctaacg
     3781 cagtagctaa agaaaaaggt gctacagtta ttagtctaac acgaagcatt gactcaccgt
     3841 taacaaaaga tgcagattat gtaatttatc atcgatttgc agagaactat gctgctaaat
     3901 tagaaaaaac aggctactgt ttagaattgg cagtagaact tttacatcaa gtagaaggtt
     3961 atgaccatta tgaagcaatg caagaaggat ttgctactat ctatgatctt gcccaaaaaa
     4021 gtgcagaatc agctcgtaaa gatgcgaaga aatttgctga acgctttaaa gatgaaaaag
     4081 ttatttatgt aatgagtagt ggtgctacac atgaagtagc atactcaaca tcaatttgct
     4141 tgatgatgga aatgcaatgg attaattctg gtaccttcca ttcaggagaa tttttccacg
     4201 gaccattcga aattgtggat aaagacgtac cgtttatatt attaatgaat gatggaaaaa
     4261 ctagaaatat agatgctcga gcattaactt tccttgaacg ctttgatacg aaaacagaag
     4321 ttgtagatgc cttggattat ggcttgtctt cacatattgc taaagaagtc ttagactact
     4381 ttaacccatt cgtgattact gcagtattta gagtttatgc agaagaattg tcagaagcaa
     4441 gagaacatcc attaactaag agacgttata tgtggaaact aacttattaa aaaatagatc
     4501 aaactaaata aggtggcttg agaaattaag ccaccttgtt ttcttcaatg tgattttata
     4561 catatggtaa aataactagt acatattgtg aaagcaggtg gcaagatgca gcgattaaat
     4621 gactatcttt atcaactaac attgcttttg aaatctacgc cttcagataa ttattcagct
     4681 cgcagtattt cgcaagcttt acagttgaat agaagtacaa tcagtagcta cttaaatgaa
     4741 ggtgttcgtg aagggctttt cataaaagta aaaagttacc cggttttatt tttacataga
     4801 acagctcttg aagaactaca tatcacactg aataactccg aaatagaatc aattgaaagc
     4861 ttgttaacaa tttctcaaaa acccgcatta gatcaagtaa ttggctctaa aggaagtttg
     4921 aaagaagcaa ttgatcaaat taaaacggca gtcttatatc ctggaaaagg gttgccttta
     4981 ttattgatcg gcgctagtgg atcagggaaa acctttctag cgaataaaat atatgaatat
     5041 gcagtagaag aaaaggtcat tcacacatcg gcacctttca tagattataa ttgtgcacaa
     5101 tatgtgagca atccagagtt actatcctct gctttatttg gctacacgaa aggagcattt
     5161 accggagcaa gccaggagca tactggtttg ctagaaaaag ccgatggagg agtattgttt
     5221 ttagatgaag tgcatcgctt atctgaagaa gggcaagaga aattatttac atttatggat
     5281 acgggtgaat tctctcctat gggggataat agtattcgga aaaaagccga tgttcgatta
     5341 gtctttgcaa caacagaaaa tatatatacg actttcttac caacttttct taggagattg
     5401 ccagttattg ttaatctacc tagatttcaa caacgtccgt cgtttgaacg tctgtcattg
     5461 attgatgaat tttttgtttc tgagagtaaa attttagcta aggaactatc tgtttctgat
     5521 gcattgattc atttcttaat gaatagtgat tttgaaggta acgtggggaa tattaaaaat
     5581 attatcaagt atgcttgcgg aaacgcatat atccaccaga agagtcagca aacaattcaa
     5641 gttaaattat tggatatgcc tttagagtac agttataaat tcaaggagca actaaataaa
     5701 cccagaaaga aaagagcaga tcgaatctac tatccagaag aaacacgaca agtgcaacta
     5761 gaaagaaaca atcagctttt tgttcaattt tttgaccaat tacttactgg attctctgaa
     5821 gtgattgaaa ataacaagga tattaaacta tttttagaag aaatggttac caaggtaaca
     5881 caagtaatgg atacgcttat ttttcaagag gattacgaaa aagagcagtc tttatacgcc
     5941 attctaaact atcatattcg tcaaagtatt gattttatgc gagaaagcta cgggtttgaa
     6001 caagatggta accgggtagt cgctttggcc aactatctat atgtcaagga taatcaagtg
     6061 atttttgaaa atagtcttca agaaaagaaa accaaagatc agcttaacga attttttgct
     6121 aatgttcttg aaacccctta ttggtatgca aaaaaaatct taagcctttt atctgagtgt
     6181 ttagatcaac ctgtgtatga agaggacatt ttctttatta cgctatattt ttatagtttg
     6241 aatgtcacga atgttaaaac aggtattaag agtattgtgc tagctcatgg ttattctaca
     6301 gctagtagta tggcgaatgt tgccaaccgt atgctgaata agaacgtttt tcaagcttat
     6361 gatatgcctt tagatattac attagagaaa attgaagcaa aattgattca attccttgga
     6421 gattatcgaa cagattcagg cttgatttta ttggtagata tgggttcact aaaccaacta
     6481 ggcggtttat tagtgaatca tctaaatgga ccactgttaa tcattgatca tatcaataca
     6541 ccgttattat tggaagtcgg ccaacaagta ttaaacaata aaagtatcac cgaaatagga
     6601 gcagaaattg aaacaagtct tactttcaaa aagcagttac tacttcccaa gaaaaagaaa
     6661 aagaaagcca tcattacttg ttgttataca gggattggta gtgcgaccca gattcaggag
     6721 attttaacga aatgcttgaa agatgcagtt agagaattag taattattcc gtatgattac
     6781 aaaaagctgt tagaaaacaa gaattttgag actccttttc aattatacga tgtcatcatg
     6841 attgtaggta cagaagatcc caaaattaat cagattccat atattggatt agatcgcctg
     6901 attaatgggg aagcaattgg cgaatttgtt cattacttgg aaaaagagct gactattgaa
     6961 gtgaacgatt tacaaaaaga attaattttc aatttttcaa ttagtaaaat tgtcgaaaat
     7021 ttaaccattt tggatccaga taaggtgcta tcttttgtac aaaaagcaat taaagaatta
     7081 tcgaagttat taaattttga tttttctaat aatcagctgt ttttgttgta ccttcactgt
     7141 agttgtatga ttgaacgaat tgtacgtaaa gaaagtgtgg atgagcaaga ggacattgaa
     7201 gaatatatgc aagcaaatgg agaaataatg gataaaattc atagcgcttt ttttgagatt
     7261 gaaagggaat acacaattga aataccagat ttagagttgc gattattgag cgatattgtt
     7321 caaggatagg agtgaattcg aatgacaatg ggagtaattt ttgatatgga tggggtactc
     7381 atagacagcg agacatttta ttttgagaga agaatgaact tctttcaaga actggagata
     7441 gatccaggat caaaccagat tgatgattat gtggggaaaa cagaagctgc aatatgggaa
     7501 acattagttc ctgaggacaa atcattaaga gaggaacttt atccgaaata tgtagattat
     7561 cgaaaaacgc atccaattga tttcgctaaa gatttacgaa aagaagtgaa accgttactt
     7621 gacttcctca agaagcggga tataccattg gcactggcat cttcttctcc agttgttgag
     7681 atagagagta tgctcattca atgtgaactt actgaatatt tttcctttgt tataagtggt
     7741 gagtcattaa aacaaagcaa accacatccc gaaatatatt taaaagcgaa acagcaatta
     7801 gactgtgact tctttattgc agtagaggat tcaacgattg gtattaaatc agcaaaggca
     7861 gcaaatatct atacggtggc actaaaacaa ccaatgcaaa tcgatcagag tgaagcagac
     7921 atacaaattg aaagtctaca agaactggaa caaattgttt tagaaaaagg ttagtgaatt
     7981 aatggaaata aggctatata tctgtgctag ctattttgac taaccaaaaa aacttgctat
     8041 aattcaggtg tagtaaaagg tgctggtaac accttttacg aaaatgcttc ggcagtgata
     8101 atgggattgg ctttttaagt tttttatttt gttcgcaatc cctaaggtca tgtgaatgat
     8161 cctagggatt gctagaatat tttgcaacat tctatctatt tcagaacgta accttcccca
     8221 gttcattggg attcattagc atacaaccaa catttcaaaa agaaattgca ctacaccatt
     8281 attagctatt ttgactaacc ccaaaaaact tgctataatt caggtgtagg taaaaggtgc
     8341 tggtatcacc ttttacgaaa ctgcttcggc agtggtaatg agtgtggctt aaaggactag
     8401 tcctttaagc tttttacttt gttcgcaatc tctaagatca agttaatgat cgataagatt
     8461 gctagaatat tttgcaacat tctatttcag aacgtaacct ttcccattcc actgtgattc
     8521 attggcaacc ctcctcacaa ccaacgtttc aaaagaaatt gtaaagttgt tggggtacca
     8581 cgaccgaaca atactacacc tgaatgatag taagttgtct cattaagtat agcatatcct
     8641 ctttttgggt aaatagaaat cggttacatt ttttatccaa gaccaagttt tttcatttgg
     8701 tcttatttgc tatacccaaa caattccgca gtatagtcga cggtattgat tttatcaggt
     8761 gagtaataga aacttgtttt ccttccccaa aacattacct ataaaggaga aaaaatggta
     8821 tcgtaattat ataggtatag gatgaaattt ttttctaaga ggagggttgt tgatgaaaaa
     8881 tttacagtta aaatttattg ttgatccatc gattgtacgc tggtttcgga ttatcaatca
     8941 atttgagcgc aatcaacttg ccacaaaagg agaattagca aagagtaatc atgtatctga
     9001 acgaaccatt caaacagatg tcaataaaat gaaggactac ttttctgaaa gtgttcaatt
     9061 tgtttcaacg aaaagtgggt attcttttca gaaggaaaga ccggttcttt ttctcaagca
     9121 gaaggagcaa ctactggaga acgaaatttt atttgagttg ttagggaatg tcttttatgg
     9181 cgaattggaa gatatgacgg agctaattga tcgttttcat ttatctgaag cgacttttcg
     9241 tcggtatttg aagcagattc aaccagtttt ggaagaatac ggcttagaat tgagtcttta
     9301 tcctcttgat ttaaaaggag aagaggcaaa tattcgcaag ttttttaaag acttctatta
     9361 tgaaggggag atgacgcccc atactcttgt tccaccaagg gatcttcatg aacttgtgca
     9421 agctacattc tatgataaat ttgagtattt ctcgattgga acagggactt ctcctgctga
     9481 attttattat agtttgtata ttgcgattga gcgtgtgaga caaggaaaaa cgatagccat
     9541 tcctcaaggt ctgattgagc gagtaattgc tagtgagaat tttcgcttaa tgtattcctt
     9601 gaaagaagcg attcaaacaa attatcaagt tgctttatca gaagaggagt tttgttggtt
     9661 gtat
//
LOCUS       DAIGSZ010000088         9591 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.091, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000088 DAIGSZ010000000
VERSION     DAIGSZ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.091"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..154
                     /locus_tag="NOB31_002537"
     CDS             <1..154
                     /locus_tag="NOB31_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI0974715.1"
                     /translation="NKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKV
                     LLGIQA"
     gene            206..352
                     /locus_tag="NOB31_002538"
                     /pseudo
     CDS             206..352
                     /locus_tag="NOB31_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            429..758
                     /locus_tag="NOB31_002539"
     CDS             429..758
                     /locus_tag="NOB31_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0974716.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            748..1035
                     /locus_tag="NOB31_002540"
     CDS             748..1035
                     /locus_tag="NOB31_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI0974717.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            1321..2178
                     /locus_tag="NOB31_002541"
     CDS             1321..2178
                     /locus_tag="NOB31_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI0974718.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYVEVE"
     gene            2179..2727
                     /locus_tag="NOB31_002542"
     CDS             2179..2727
                     /locus_tag="NOB31_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974719.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            2987..3620
                     /locus_tag="NOB31_002543"
                     /pseudo
     CDS             2987..3620
                     /locus_tag="NOB31_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(3665..4614)
                     /locus_tag="NOB31_002544"
                     /pseudo
     CDS             complement(3665..4614)
                     /locus_tag="NOB31_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300609.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            5216..7060
                     /locus_tag="NOB31_002545"
     CDS             5216..7060
                     /locus_tag="NOB31_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0974720.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            7116..8582
                     /locus_tag="NOB31_002546"
     CDS             7116..8582
                     /locus_tag="NOB31_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0974721.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            8619..9461
                     /locus_tag="NOB31_002547"
     CDS             8619..9461
                     /locus_tag="NOB31_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0974722.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT         3294 a         1473 c         1936 g         2888 t
ORIGIN      
        1 caataaattc tatcgaagtt tacgcactgc ctctaccacg attaaaggca tggaagccat
       61 tcgaggatta tataagaaaa cccgaaaaga aggcactctc ttcgggtttt cggtctgtac
      121 tgaaatcaag gtattattgg gaatccaagc ttaaatcata gataccgtaa gggattttat
      181 tctttattta aaactttgca acagaaccca atcatttgag aagttaaaac ctacacatga
      241 aggtaggtat tttagaagat tgaatagaca acaccgggtt gtttataagg tagatgaaga
      301 tgaacacgtg gttgaaattt attcagcaag gacgcattac gagtcacagt aattacttgt
      361 aaatacatta tctcgtggta taatgtattt actaagtaat tacatactgt tagaaatgag
      421 ggatttaaat gattacaaaa acaagaaaac aaggcaattc aatcatgttg acagtaccta
      481 aagattttaa tgttcctaat ggagtcgaag ttgaagcaaa gttggtagag aatggtattc
      541 tttatgaatt tgttgaacca caaaaagaat tttatgattt tagcgaagat attttgtctg
      601 atataattgc agaaggctac gataaagatg agattcttgt agaatttaag aatagaaaaa
      661 acaaaatgca ttcttccttt agagatattg ctgaagatac acttactaat tctaaagtaa
      721 tgactaaaga ggagttggca acagaaattg gcttatgaaa tcgttccttc aaaacatgtc
      781 attaagtatt taaaaaagct aaaagagaag ccattgaaag aaaaattttt gaatttaatt
      841 tatgatgaaa ttgcgattga tccatataag ggtgaacaaa aaactgggga tttatcaggt
      901 atttggtcta gtgggttcaa atatgcgggc acaacatata gagtagctta cgagattata
      961 gaaaacaagg ttattccagt attgttatgt ggaacgcatg aaaactttta tgaacagttg
     1021 aaaaaattaa tctagtgatt tgttgtcgtt cttaagaagg acggcttctt ttttatcgaa
     1081 aatctgattc gtctacatga ctaaagtcgc gagtattctc tgcttctcga taaattaaat
     1141 aacgtcatta ctttgaggaa agctataaat caatatattt cagcttttcc ttatttatgt
     1201 actacctttt acttattaat tataaggtag tacatatata tctttttttt ggtagtaact
     1261 aaaaataaat atgttataat agtatcaaat gaatattgct aaaagaaaag aggtaggaac
     1321 gtggtagcga agaaatatgt aatcggtaat tttaaaggtg gcgtaggtaa aagtacgtgc
     1381 gcgcaaatgt tagggtttga atcagcagtt aatgaaggaa aaagaacctt gataattgac
     1441 ttggatatgc aaggaaatac ttctgatgtg atgaacttaa cgcatatgaa cttcactaac
     1501 gaagaaggag gcggagaagg tgaaccgatt gtttacgaaa atactgtgac tgacgtgttg
     1561 ataaacaatc ttccacctaa agaggctgtc tataaagtaa tcaataacct ctatatactt
     1621 ccagcagaca tgtcctttga aatgtatgat gattggatca aagaccaata taatgattca
     1681 ttatcccaat tcaaatatat gaaagaaaag ctagaaccat tatttgatga gtttgacgtc
     1741 atctatttag atgtcccacc ttctatttct gtatatagta aatccgcgat gtacattgcg
     1801 gattgggcaa tcgtcgtctt acagacccaa gtaaaatcga tgagaaatgc gatgcaatat
     1861 cttgagtata tggacttttt tgtgaaagaa tttgatacaa atttatatgt tgctggtgtt
     1921 attcctttca tgttggaaag cggtgacgca gtagatcagg aaatgtataa acaagcccaa
     1981 gagatttatg gggaacattt gattaaaaat gttgtactca aaaatgcgcg cttaaaacga
     2041 tacgacggat caggtattac gatggagaag acaaagaaag gtctcttaaa acaatgggat
     2101 cgcaaaagcc acgaattatt tatcagtatt ttgaaagaat tggaagaaca cgagaattgg
     2161 tatgtggagg tggagtaatt ggctgacatc aaaggacttg atatttttgg gaacaacaaa
     2221 ggactcgcca aaataaaaaa agaagcagaa gcaaagaaaa agcagcaagc aattacacca
     2281 tctgaaaata agcaattaga agtgcaccaa gttcaagaaa taaaaacttc ctccaatgtt
     2341 gaaagacaga gtagaggaag aacaaaaaaa gttggcgcac caatcagaaa gtttgataag
     2401 gtttattcca ccaagcatcc tttaaaactg tcgactttgt taaatgcgac ttccagagtt
     2461 ttagtagaaa agtatgagac taatatgaca agagatgaat tgcttagaaa agctttagat
     2521 gagtatatta aacagaatct tacgcaagaa gataaacaag atttgtttaa tgacgtggtg
     2581 aaagaactag acttgttcag agaaaaatat ccaattgttc cagaattaga tgatcgtgga
     2641 gaaataataa gaactaccag tcagataaaa caagataccg aagactcact gcgcaaaggg
     2701 tggggaatga ataataaagt tagataataa tcaaagaaga actaagtaac tacctttaaa
     2761 cggtagttac ttagttcttc tttgatttgc gtgaaataga ggggatttat ttttctggtt
     2821 acgtgattaa aaaatccaaa aaatgagcat aggaacggtt atgattttag ggtgtgtttt
     2881 aatgagatat tgtgatttca ttaataagtg tatgataatc tgttgttgag ttagtaaata
     2941 agtaatagag ctaactctaa aataaaacta ttaggaggag atgtagatga aaaagtttaa
     3001 aaagaaaata tatttaggat tggttgttgg ggtgagtatg tttgggttca tggctcatac
     3061 taaacaagta actgcagata ctaaccaaaa agaaaggatt atgagccaat tagatgactc
     3121 tcaaatagag tatgtaccca atgagctaat tgtcagttta aaggctacac aaagaatttc
     3181 aacagagaaa aataaaccgc aaaatttatt gggtgtaaaa gttatggtgg aaaaagattt
     3241 gactcttagg acaaatgaaa gcgattataa taagcgagat caagtattat tagtgaaatt
     3301 gaacgaagaa attagtgtgg aagaggcagt aagaacattt aatgcttctg atatggtcaa
     3361 ttatgcagag ccaaactatg tggttgaact agagccgttg aatgatgttg aggagccaaa
     3421 tacaactgat tctttaggaa atcgataacg atcctaattg gagtaaacaa gctaatttaa
     3481 gagagattag catgccatcc gcttgggaag aaaccaaggg ttctaaggat gtgaaggtag
     3541 cggtcattga ttcaggaatt gattatcaac atgaagatct ttctggaaat gtagatgaaa
     3601 gtttgggata cgattttttt tacttttttc aagaaaataa taattcagaa tattctgact
     3661 atatttatgc aacactagtg actttaggag aaacatcaat agccttgcta aagtttttgc
     3721 tttcgctaaa gagagtattt tcgataattt gtttttttct aaaatacctc gttcctcaat
     3781 atttgggata tggatatgta tagggattct tcgcataaag gtttccagaa aatcctcttt
     3841 gccttctgta gtcgcaaaaa ctaaacgtac attggaggcg tgatggatag tttcaccgac
     3901 tctagaataa gttccgccat ccatataaac aaatagtttc tcttgccctt caggaggcaa
     3961 tctgtgtact tcgtctaaaa acagtactcc accgtctgca tcttgcaaca atccatttcg
     4021 atcttcatct gcgccggtaa aagcaccttt aacatagcca aatagtatcc ccgacaataa
     4081 ttcaggatta ttatggtatt gcgcacaatt aagtacttta aaaggagcat tctcatgaat
     4141 aacgttcact tttttcataa actgataagc agtatgaaca aaaaaacttt ttccaactcc
     4201 agtatctcca gtgatcatca taggaagccc tcttccagga tagaagacag cagttttcat
     4261 ttgttccacc gcatcggata agctcatatc atacccaatc atcttttgta gaatggaatc
     4321 tgtagaattg ggctccaagt ctgtttttaa ttcagatata ctttcgtata catcttttac
     4381 cggaatcaaa aagtgctctt caaagcgctc tttgatggca aataacactg gacgagtatt
     4441 gattttaaat agaacgttct ttgcaactaa gtcattggca agtttactgg catttgttct
     4501 tcccgttctt aaaaattgcg acaggtcatt tgtgtcaaaa aagcactctt ctaaattact
     4561 gatgccaatt tcttcacatt ttgtgtttgc ataagtcact atatcatttt tcatcttata
     4621 aacagtcctt tctaaacttc tatcccttaa ataaatagca aaaaaaagga agcaatatcg
     4681 atatgctgtc ctcttaattt aataaagcgc taatctaatt cactgtatta tcatttttta
     4741 gtagtatagc acaattatga atgccttttc tttatatcaa ataaagttta tataaaaaac
     4801 ctcatcctgc aagaaagaaa aaatgaaccc attcttttta tactaggtct taaaaagaca
     4861 gaacatctgc tagaagatag aagagaataa gagttatata tgttggaaga tattcttaga
     4921 aaaaagacaa aacttttaga acacgaaaac tatattgaac gaataaaatg aaaaaatgat
     4981 taaaaaatca ttttattatt tacgtttaca ttctaatatg ttaaattgaa tataacttaa
     5041 acaggcatgt gactggtaat gcaggcagga cctaaataag ttgaataaca atgtatgcgt
     5101 ttcaatacac gtttgccttg ttgtcaattt atttagtttc tgcctgtttt ttgtgttgag
     5161 gatggccact tcgactcaaa agttcatcac tcaaaaaaga aaagagggaa acaccatgaa
     5221 ttacaaacaa acagcagaag aagtattgca gtacatcggt ggggaagaaa acatatccca
     5281 tttggagcat tgctcaactc gtttacgttt tacgttaaaa gacaacagca aggtaaatat
     5341 gagccagtta gaaaaagtgg atggcgttat gggcgttcgc caaaatgtgc aatgccaagt
     5401 aatcattgga aacgatgttg ttgaagtgta tgatgaagtg aaagcgttat taggtgacaa
     5461 tgtttcaaat actgaagaag caccaaaaca aaaacaaaaa ttaggttcag ttctattaga
     5521 ttttattatt tctattttcc aacctttaat tcctgcgatt gcaggtggag gagtattgaa
     5581 gtccttgttg ctactagctt ctatcttagg gctgattagt gaccaatctc aaacctatca
     5641 gattttaaat ttggtcggcg gggcaccgct ttatttcttg cctattctgg tggcaatgac
     5701 tacggctaat aaattgaaag tcaatcaatt ggttgcagta tctgctgtcg gtgcattgat
     5761 ccttcctgaa atgacagcta tgttggcgga aggtgctaca ttcttatctt ttggattgga
     5821 taatatagcg tatgcatctc aagtattccc agccatctta actgttttat tttatgctca
     5881 acttgaaaaa tggtttacaa aagtttcacc aaaaccaatt cgtattttct ttgtacctat
     5941 gatgagctta ttgattacag ttcctattgc tttgttgctt ctaggaccat taggttataa
     6001 tgtaggaaca gctttctctt ctatcattgt gtctttgtac aatcaatttg gatgggttgc
     6061 aaccggagtc ttagcagctg tactgccatt aatggttgta acgggtatgc ataaagcaat
     6121 gatcccttac gctgtttcat ccatgagtga attgggtgca gaacttcttt atctcccggc
     6181 ttcattggca cacaatattt cagaagctgg cgcatgcttt gctgtcagta tcaaaacaaa
     6241 agacaaaaaa ttgaaatcta cggctgtttc tgcgggtata tctgcattat tcggaattac
     6301 tgaaccagct ctttacgggg taacgattct gcacaaacgt gttttatatg ccgttatgtt
     6361 ttctagcctg atcgggggag catttgcagg aatcgttgca cttcaagcct ttgctttagt
     6421 gggtcctggg attgcaagta tcacgatgtt cgctgacaaa gctgacccaa tgaatctggt
     6481 ttgggcattt gcagtatcgg ggatttcatt tgtggttgct tttgctgcag cgttggttct
     6541 ttataaagat aaagaagttg tcaatgaagt tgaaactaag atggaaacgg ccgttgtttc
     6601 agatgctgtt ctttcaagtc ccgtgaatgg aaaagtaatc tcactatcag aagtaaaaga
     6661 cactgttttt tctagtggta tggtaggtga tggagtagca atcattcctg aagaagggat
     6721 attagtagct cctgaagatg gagaaatcac aatggtattt gaaacgaagc atgctattgg
     6781 tttaaaaacg gctaatggtg cagaacttct ttttcatatt ggtattgata ctgttcagtt
     6841 agaaggaaaa gggtttgagg catttgttcg ttctggtgaa aaagtagcca aaggacaaaa
     6901 gctgattgca tttgatattg atttaatcaa agaagcagga ttcgacccca cagttatctg
     6961 tgtggtaacc aataaggata attacactat ccgttcattt aacctagaaa aattggtaac
     7021 caatgatagt gatctcttag ctatcagtcc gatagcttaa acacaagata gtgaaaaaaa
     7081 atatattgaa tgaaggaata gaggagaata gaataatgac aaacacaaca agttttccaa
     7141 aaggattttt atggggcggc gcgatagcag caaatcaagt agaaggtgct tggaatgtag
     7201 acggtaaagg tctttcagta gcggatatgg ctacttataa accaaattta gacaacaaag
     7261 attttgctgc tcatatgcat gtcaccctgc agtctataaa agaagctagt gaagacaaat
     7321 ctgataaatg gtacccaaaa agaaggggcg ttgattttta tcatcactat aaagaagatt
     7381 tagctttatt tgccgaaatg ggctttaaaa ccttgcgcct ctctattgct tggactcgct
     7441 tgttccctac aggagaagag ctggaaccga atgaaaaagg ggttgcattt tatgaaaacg
     7501 tctttaaaga aatgcaacgt ttaggaattg agccgattgt gacactatct cattatgaaa
     7561 tgccattagc tttagcagtt aaatataatg gctgggtgga gcgtcgagta attgatgatt
     7621 ttgttcgctt cgctaacgtt tgttttgatc gcttcggcaa atacgtaaaa tattggctga
     7681 catttaatga gatagacagc atccaccgtc atccatttac aacagctgga attatccaag
     7741 agaaaagcgc agaaggtcaa gaagctcaag atatctatca agcattgcat catcaatttg
     7801 ttgcgagtgc gttagtgaca aaagatgctc atgaaaaaat tccaggaagc caagttggtt
     7861 gtatgttaac gaaattgatg acttatccat taacttgcgc accagaagac gttgagctga
     7921 ccttgaaaaa gaacttagaa aataattttt atgcagatgt tcaagttaag ggagaatatc
     7981 ctgctctaat cgaaaaggat ttggaaaatc ggggaattca gattaaaatg gaagatgaag
     8041 atcgagaaat tttaaagaaa cataccgtag attttgtttc tttcagctat tacatgtcca
     8101 tggcagaatc agctgatcca aacgcagaac gcacaccggg aaatactgtt ttaggggtta
     8161 agaatcctca tttgccttca acagattggg gctggcaaat cgatccaaaa ggtttgaaaa
     8221 tttcgttgat cgaactttat gatcgttacc aagtaccgtt gatgattgtg gaaaatggta
     8281 tgggagcagt cgatcaggta gtagatggta aaatccatga tccgtaccgc atcgactact
     8341 ttaaagcaca cttccaacaa atgaaagaag caatcgatga aggtgtagat ttgatagctt
     8401 atactagctg gggaccaatt gatttagtta gtgcaggaac ttctcaaatg tctaaacgat
     8461 atggatttat ttatgtggat gcagacgatg aaggaaatgg gacatataac cgcttgaaaa
     8521 aggattcgtt caactggtac aaagaagtga tcgaaacaaa cggtgcatcc ttattcgagt
     8581 agtctcgatc tttttaagca gcgatagggg gataatgagt gatttcaata aaaaaagtat
     8641 tgaattcaag tgtggtactt gttgaagaaa atggcaaaga aatgattgca ttaggtaaag
     8701 ggataggctt tggacagaaa gctggggatg aaatatcagg agataaagta gataaaatat
     8761 ttctgccttt tgaagaaaag aaatcttcac aactattaga gttagttgaa gaaataccta
     8821 ttgaattttt tgaaatcact cgtactatcg tttttgaagc agaaaaagga ttagataaaa
     8881 aactgaatcc tggagtctat ttaaccttaa cagaccacct gcattttgca gttgaacgcg
     8941 cacaaaaagg ggtaaatatt gcaaaccgtt tgtactggga aataaaaatc tactatccca
     9001 aagaatttca aattgggaag tacgcactca cccttttgaa cgagcaatat ggaattgatc
     9061 ttcctaaaga ggaagcctca aacattgctt tccatttgat caatgcacaa tcggaagatc
     9121 ctgatagcgg cgctggattc aagtatgcaa aaatgatcgg cgggatcgtc aatttggtcc
     9181 ggtattcgtt gcagaaagat atcgatacta attcgatcca ttatgcccgc ttcattacac
     9241 atgtacgttt ctttgtagaa agatattatt ctgatgcttt gttggatgat ggtgaggaag
     9301 aattctacaa tcaaatgtgg atcttatacc cgtctgccat ggaaagcgca gctaagatca
     9361 aagactacat tgaaaaagtt tatcataaaa caattccgaa cgatgaagtt gtatacctag
     9421 gtgtccacat caatcggttg atgaaacatg ctaatgggtg agcgctcagt aatactattg
     9481 atgcttttaa aatctttaga gatggattat agtaaaaaca aggtgatttc cagctgtttg
     9541 ttatctataa gagacattta aaaaggatta acgtaagata ataaaaaatc t
//
LOCUS       DAIGSZ010000089         9591 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.092, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000089 DAIGSZ010000000
VERSION     DAIGSZ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.092"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..643)
                     /locus_tag="NOB31_002548"
     CDS             complement(<1..643)
                     /locus_tag="NOB31_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HCI0974723.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTK"
     gene            complement(645..1409)
                     /locus_tag="NOB31_002549"
     CDS             complement(645..1409)
                     /locus_tag="NOB31_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HCI0974724.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(1417..2094)
                     /locus_tag="NOB31_002550"
     CDS             complement(1417..2094)
                     /locus_tag="NOB31_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HCI0974725.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(2131..3516)
                     /locus_tag="NOB31_002551"
     CDS             complement(2131..3516)
                     /locus_tag="NOB31_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI0974726.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(3726..3810)
                     /gene="ffs"
                     /locus_tag="NOB31_002552"
     ncRNA           complement(3726..3810)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="NOB31_002552"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3833..4348)
                     /gene="tadA"
                     /locus_tag="NOB31_002553"
     CDS             complement(3833..4348)
                     /gene="tadA"
                     /locus_tag="NOB31_002553"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HCI0974727.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            4455..5312
                     /locus_tag="NOB31_002554"
     CDS             4455..5312
                     /locus_tag="NOB31_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0974728.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(5393..5728)
                     /locus_tag="NOB31_002555"
     CDS             complement(5393..5728)
                     /locus_tag="NOB31_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974729.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(5795..7165)
                     /locus_tag="NOB31_002556"
     CDS             complement(5795..7165)
                     /locus_tag="NOB31_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HCI0974730.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(7243..7779)
                     /locus_tag="NOB31_002557"
     CDS             complement(7243..7779)
                     /locus_tag="NOB31_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0974731.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            8088..9569
                     /locus_tag="NOB31_002558"
     CDS             8088..9569
                     /locus_tag="NOB31_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0974732.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         2907 a         1969 c         1502 g         3213 t
ORIGIN      
        1 tttttgtttg tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta
       61 ataatacaaa aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga
      121 ttggatcagt aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa
      181 ggataaaaaa gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca
      241 tgccgatttg aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga
      301 taaacaaaat actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa
      361 ttttcacttc ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga
      421 ggatggtttt gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg
      481 tctcttgatc taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata
      541 gtggtcgaaa gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga
      601 acaatccagc atattccatc cactgccatc tcgaattttt catattagaa gctccattca
      661 tccagtgatt gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt
      721 gtaaaacctg ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct
      781 gtttcatagt tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg
      841 gctttatcca taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct
      901 gtctctacaa aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata
      961 ttcttatctg ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta
     1021 actacttttt cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct
     1081 tcttcccatg taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca
     1141 tagacttttt tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg
     1201 tagactgtct ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt
     1261 tctggtgact tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat
     1321 tcttccacaa atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct
     1381 aaatcaatta aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt
     1441 aaatgctgtt tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga
     1501 ggtttttgct gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac
     1561 tggtcctttt ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg
     1621 agttgtcttt tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt
     1681 gcaatattcg taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg
     1741 attatccgct tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat
     1801 ataatcatat cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc
     1861 ttcacgataa tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc
     1921 taacagtgtc actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc
     1981 caaagcagct gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt
     2041 agcaatttct gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc
     2101 accacctatc ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta
     2161 atctcctacc acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc
     2221 aatcgttgga aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt
     2281 attcagatcg attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat
     2341 tccattatag accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata
     2401 gttacgtaaa aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc
     2461 acccaatgtg acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg
     2521 attgacccgc ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc
     2581 cgtctttcct cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa
     2641 gatatctaga ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg
     2701 cccacgttct agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc
     2761 ggtagggatg gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg
     2821 gacttcaccg acatactgcc cgtactttcc agcggctgct atttggacat cattgattac
     2881 gtgaccttct ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat
     2941 ttcttttgca atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc
     3001 cacttgtgaa cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc
     3061 ccagccattc ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt
     3121 cgtctggtgt ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt
     3181 atttttatcg aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt
     3241 caactcttct ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc
     3301 aacttcattc atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca
     3361 acgatccaca aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt
     3421 ttctcgttta cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg
     3481 cagatcattc gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct
     3541 ttatcatacc ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc
     3601 tgccttgaag caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag
     3661 gaacattcat ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg
     3721 tttcattata atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac
     3781 acgcttcaca agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt
     3841 cattcgttga ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt
     3901 cagtcaaaat catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt
     3961 taaaccgctc gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat
     4021 acgcgccgaa ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac
     4081 aaggctctaa ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac
     4141 aggcttcctt gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa
     4201 ggttatatcc tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt
     4261 catgaagcat ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt
     4321 ctactgcatc aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt
     4381 tactttagca tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac
     4441 aagaggtgaa caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa
     4501 aaaactctcc agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct
     4561 ggatcaaaca agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg
     4621 taatcaacga tcaaaaaaaa cacccatggt atcgctatct ttttaaagat gcttcttgtg
     4681 ttcaagaaaa aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa
     4741 aaaaagaatg gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt
     4801 atacagacac agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatgctactg
     4861 aaatcaacgg tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg
     4921 ttggttcttt ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa
     4981 tttttttaac agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg
     5041 tggctttaca ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca
     5101 tagaactgat caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag
     5161 gcaatgtcag ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa
     5221 tcgaaaaatt tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt
     5281 gctatctttt attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa
     5341 ttttgtcaca accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca
     5401 ttttttcaac aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat
     5461 caccataaac agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag
     5521 aatccaagtc actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa
     5581 atttgtcata gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca
     5641 ttacttttcc cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc
     5701 cgattgttac ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca
     5761 tagcatagac aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga
     5821 aaaagttctt tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata
     5881 ctagcaaaac ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt
     5941 gccattcctt ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg
     6001 ctaatgcata gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac
     6061 gtacgacttt taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt
     6121 tgaacactaa aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga
     6181 gtttttcctg ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat
     6241 gcatctgatt ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt
     6301 tatgaggcca tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc
     6361 ctgaactaac ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa
     6421 gccagctaat gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt
     6481 gtcctttatt ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac
     6541 agtatagcgg agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc
     6601 cttctcctga acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga
     6661 caagttctgc gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat
     6721 tttctgataa aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc
     6781 ccttcatttg agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa
     6841 ctttttcacc gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc
     6901 tatattcata cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct
     6961 cattgctgta gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc
     7021 ctgccggttt tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag
     7081 aaaaaaaatc ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg
     7141 gtaacgttgt cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt
     7201 acgaaaaata aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt
     7261 taagatattt tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat
     7321 ttcaagaaaa tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac
     7381 caattcaagc gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg
     7441 ccgcttaaat agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc
     7501 atggatagaa aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca
     7561 ttcagctaag tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc
     7621 gctgattgat ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa
     7681 ctctcttgca gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag
     7741 caaatattct ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca
     7801 tctacccata aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca
     7861 tatttagtta tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca
     7921 aaatacccta ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta
     7981 tataaaaaag aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac
     8041 agtttttgtc taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag
     8101 caagaaaaaa agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac
     8161 aagaattatc caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa
     8221 taaatgtatc actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag
     8281 gagagatcca aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa
     8341 aattatgcta cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc
     8401 cacaaactgc tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc
     8461 tcgaaaaact gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat
     8521 ctgtaaaaaa ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact
     8581 tttttctttc agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg
     8641 cactaaaaat gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata
     8701 tctacttgct gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa
     8761 cttcttctga aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat
     8821 actttacttc tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact
     8881 ttaattattt tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga
     8941 ttggtttttt attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga
     9001 cttacttaac tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt
     9061 attttcttgt gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt
     9121 ctacactttg ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga
     9181 aattaagaga aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc
     9241 aataccttag tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca
     9301 tccatttgca gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc
     9361 agttatttcg caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca
     9421 ttacagatca gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc
     9481 acaatacagt gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag
     9541 gttatgagaa caaaacaaag aggatgtgac aaaattcttg tcacatcctc t
//
LOCUS       DAIGSZ010000090         9559 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.093, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000090 DAIGSZ010000000
VERSION     DAIGSZ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9559
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.093"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..807
                     /locus_tag="NOB31_002559"
     CDS             <1..807
                     /locus_tag="NOB31_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0974733.1"
                     /translation="VLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLECY
                     FSRFSLATREAVQWIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKE
                     TTARLKGTSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIVDRLL
                     SACPNLRQGYQLYQDILYAVKKRDQSLFEDCLNREVSGLPETYTTTLRTFKKFLPQIQ
                     NALHYSYSNGPLECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGKTFLTK"
     gene            927..1127
                     /locus_tag="NOB31_002560"
     CDS             927..1127
                     /locus_tag="NOB31_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCI0974734.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            1203..1400
                     /locus_tag="NOB31_002561"
     CDS             1203..1400
                     /locus_tag="NOB31_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974735.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(1697..3244)
                     /locus_tag="NOB31_002562"
     CDS             complement(1697..3244)
                     /locus_tag="NOB31_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HCI0974736.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(3328..4131)
                     /locus_tag="NOB31_002563"
     CDS             complement(3328..4131)
                     /locus_tag="NOB31_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCI0974737.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            complement(4134..4916)
                     /gene="phnE"
                     /locus_tag="NOB31_002564"
     CDS             complement(4134..4916)
                     /gene="phnE"
                     /locus_tag="NOB31_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HCI0974738.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            complement(4913..5692)
                     /gene="phnE"
                     /locus_tag="NOB31_002565"
     CDS             complement(4913..5692)
                     /gene="phnE"
                     /locus_tag="NOB31_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HCI0974739.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            complement(5664..6455)
                     /gene="phnC"
                     /locus_tag="NOB31_002566"
     CDS             complement(5664..6455)
                     /gene="phnC"
                     /locus_tag="NOB31_002566"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HCI0974740.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            complement(6516..7445)
                     /locus_tag="NOB31_002567"
     CDS             complement(6516..7445)
                     /locus_tag="NOB31_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HCI0974741.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            7640..8323
                     /locus_tag="NOB31_002568"
     CDS             7640..8323
                     /locus_tag="NOB31_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HCI0974742.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            8484..9527
                     /locus_tag="NOB31_002569"
     CDS             8484..9527
                     /locus_tag="NOB31_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCI0974743.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
BASE COUNT         2928 a         1953 c         1898 g         2780 t
ORIGIN      
        1 gtcttatgct ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc
       61 atgatggacg gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat
      121 ttagaatgct atttttctcg gttttcatta gcgactcgtg aagccgttca atggattgtt
      181 attgatatgt atgcgcctta tgtttcattg gtgaaaaagc ttttcccgaa tgctcagttg
      241 atcatcgacc gtttccacat cgtccaacat attggcagaa ccttcttgaa tcatcgagtg
      301 aaagaaacca cggcacggct taaaggaact tcccactctc aacgagggtt agggaaaaaa
      361 ttgaaacgct attggaaact cctacaaaaa gaagaagcaa agttaaacta cgaaaaaagg
      421 gtttggcgtg ccagttttaa agattatttg actgaaagtg agattgtcga tcgactgtta
      481 tctgcttgtc ccaacctgcg ccaaggctat cagttatacc aagacattct ttatgcggta
      541 aagaaaagag atcagtcatt atttgaggac tgtttaaaca gagaagtcag cggtcttcct
      601 gaaacctata caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg
      661 cttcactaca gctattcaaa tggaccattg gaatgtttaa acaaccacat caaagtatta
      721 aaacgcaatg cgtacggctt tcgcagcttt tacaatttca aactacggat catgattcgt
      781 catggcaaaa catttttaac caaataaaca gaacagaaag agagtttctt ctttctgttc
      841 tgtccaaatt attctaagat ttctctttac caacatcatt tgacaaagag cctgtattta
      901 ttactgtcga ggacaatggc atcggcatga ttgaagagga acaaaaaaac atttgggatc
      961 gctattataa agccgatccg tcaagtaaaa atacaaagat aggcgagtca ggtcttggat
     1021 tatcaatcgt gaaggaacta gtgcgcctgc accacggttc aattgaagtg accagccgaa
     1081 aaaatgaagg aacgaccttc ctgatacaat ttccaaaaga aaaataaaat taccagtaaa
     1141 aaaccgtgga gagatagctg ctattgattt ttgctatgtc ttttctttga gaggtatccg
     1201 gtatggtgga gtgtctgaaa aataaaaaaa tggaggccaa ttttgtgaaa gctgttattt
     1261 ctggaagtat tgttttccaa gaagaatatc gagatatgga aaaagatttc agtaaaaaag
     1321 gcattgaatt aattgattat cctcgctcat gtccgatcct agacaaagag tatccagaaa
     1381 tcttgacgac ttttttttaa atatcgcagc agcggattta ttttttgtat ttaatcaaga
     1441 tcggaaaggg gtattaggct atattggtgc cgcaactttt tcagaaatga agtattgtct
     1501 gatgcaaaat cttattcatg gaaaaaggat caaaatagtc ttatttaagg aaccatcaga
     1561 ggaaaatttt ttgttttgat gaggtagatc gctggctaaa gaatggctgg atggaaatca
     1621 gacagcctaa caatttggca taacaaaggt gtgggcaaaa aactgctcac acctttttga
     1681 attttttatt tatatactac aaaatcactt gaaaattatg attcactttt gcttcgatgc
     1741 gtgggtgaat attcaaatag tcggcaatta attcggtcat gtcgatttgg atttctcgga
     1801 caattttctc cgcaccaaac atcgcataat ttcctccgcc gattgcccga tattgatttg
     1861 tcaccacttc cagcatttgt tgcggaagaa cggggtgacc tttaaaacga agttcggtaa
     1921 tccgttgtcc aacaggctgt ttcatatcaa tagtgtactg aatcccttca tacatgtcat
     1981 aattgtagta ctggggctta ggctgaataa aggctggatt gaatacgatt tggttatttt
     2041 ctacagctaa ataatttgcg gtctgctcca acgccgctct caaatctgca ccatttattt
     2101 gaatcactgc cagagtattc ggataaatat agttggtgat gacgtcccgc atcgtgatcg
     2161 tctcaccaaa gccttttcct tcattattga ataacgcagt tccagaaatc tctgagccgc
     2221 tggcaaataa ttgtacacga ttaataaact ctacataggg atgttcctca agacgagcct
     2281 gcatcggatc attaatacgc atatttccgt tcactttacc taagggttga tccaaccatt
     2341 tctctagttt ttcttctacc ggtacgatcg ctgcaagaat ttctggatca ggctctgatt
     2401 tttcaactga gtgtaaagca acctggtgat ctgtaacaac cacttgcccc tcttttttct
     2461 cgacggtaag acgaatttca ccgatgaact cgccacgata gcctggttga acaacgggaa
     2521 ctccatgaac cgtttcagca attttccggt gctgatgacc ggtgaaaagg gcgtcaatgc
     2581 cttcaacctg ctgcaatagc tcgtagcctt cattctctcc agttagcgct tctgtgtcct
     2641 caccggttaa caagtctttt tcaaatccgc cgtggtaact aacgattacc aagtctgctt
     2701 gtttccttaa tagaggaaca tattcttttg ctgtttcgac gatactctta aacgtaattc
     2761 ctgctaaggt ttctggcttt tcccagtgag gaatgtattg tgtcgttaat cccaagatag
     2821 caatttttac acccaccttt tcgataatct tataggcgtt tccaaagtat ggttggtcat
     2881 ttttgttcac catattggct cctaatatag gcgcttgata attcttaatc gcttcctcga
     2941 gataatccac accatagtta aactcatgat ttcccaacac ttgaacatca tagctcattt
     3001 ggttaatcaa gtctgtaagc tctttggctg aaccatattc tttagcaaga taataactca
     3061 aaggagaccc ttggatgaaa tcaccatttt cgatcgtaat taccggtcca tctgcttttg
     3121 cccgtaattc cttcagtttc gacgatactt tagccgttcc taaggccaga tcggttctgc
     3181 cggaatagtc tgttggtgaa acatagccat gcatatcact tgtctctaaa aacgtaatgt
     3241 tcattctgcg tgctccttta gctgactcaa aatagaaaaa ccgaagcgta ttcagctgtt
     3301 cggtctcttt ttttgattta taatgcctta atccttcatt tgaagtgttt ttaaaatgtt
     3361 gcctggaata aagttttctg ttgtctggcg aacaatcctt ccttgatcga gatgataaag
     3421 gttataccca tgacgttctt caaagcgtac gaagccatcg ccttcatctt caccaacaaa
     3481 ggacatactc gatacagtaa aataggggat cccattaatt tcatcagtaa atgtgtgatg
     3541 ggtatgaccg tttaggatac agcgaatatc gtaaggtgcg attagcttca agaaacgttc
     3601 ggtaccaggc cattttggta tactgctttg gtgagacagt agatgatgat gggtgaccaa
     3661 gaaaatcggt tggtcttttt cttgctctaa ggcttttttc agccattgaa attgctgatc
     3721 gtccactata ccatctgcgt atccatagct tgaattatca aaggaaatca ctgtaaactc
     3781 aggatatttg actatctggt tgtacggggc agaagaggcg gcttcatcgc accagcctac
     3841 ccaaaaatgt tctttgatat cgtgattgcc tagagtaaca agaatcgtcg tttctcctag
     3901 cgcattttcc agccaagtct tcaagtatcg ataatcgtct atttcgccat cttcggttaa
     3961 atctccgctg ataatcacaa ggtccaaggg tgtttgctgc aggagatgat gaatgcattg
     4021 ctccagaggg ataaggggat tctgcatcgt agccagcatt cccttatagc cttcttcaca
     4081 agcctcatac tctctgcgaa agtgtatatc tgatatatgc aatatattca ttcttatctc
     4141 aatctctttc ttataattcc ggttatttga tctaaaataa acacggttac gactacgcca
     4201 atcaaaataa tactcacttt gctccaagac cgagtttgaa tcgcgaatat caatggagca
     4261 ccgattccgc cagcgccaac taagcctaag gtagccgcac tacgaaccgc tatttcaaaa
     4321 tgatttaatg ctaaagaaca ataaatcggc atcaaatagg ggatgcgaac aaagaaaatc
     4381 gtttgccaaa aatttgctcc taccgcatgc atttcttcaa caagtcgctc atccatcgct
     4441 tccatttctt ctgtaaaaag tttgccaagc attccgatct gatggacgcc aatcgccata
     4501 acaccagcaa aggggccagg tccgacgact ttcacaaaaa taattgcaaa aactagttca
     4561 ggaaaagctc gtaaaacatt acagataagc ttgccaattt ttgttaccca tggatgtgct
     4621 tgccagaggt taaccgcact gatcaaggta atgggaatcg ctaataccgt agcgatcatt
     4681 gtccctaaac aggcgattcc aatggttaat aatagcaaac taatcaaatc ctcgccgctg
     4741 ccatcatata gaaactgcca atcaggctga cctaaccctc tcaaaacgtc cattcccatg
     4801 gaaggagaga aggtgcttaa tccagagtaa tccagagtag cggccgacaa aataacgaga
     4861 atcactaaag caactaatga taaaagggtt cttctgttca tttcacgaag catcataaca
     4921 gggacctcct gacacgttca cttaatttat caacgatcgc gacagttact aggatcgtta
     4981 gaataatgat tgaaactcgt tcataattca aaagcgcaag tgaggaattt agaataacgc
     5041 caataccacc agctccgaca tatccaagga cagtagaagc acgaacattc acctcaaacg
     5101 cgtaaaaagc atagctcgca aactgactca aaacttgtgg agcgatcgac caaatagcga
     5161 tttgcatttt atttgctcca acagccgcag cggcttcaat cgggccaaag tcaatggttt
     5221 caattgcttg aaacattaat tgtgacacca taccaaaagt aaagacagcg atagtcaaca
     5281 cgccagtcgc ttcaccaatt ccaaacacag caacaaaaag cgcggctaaa agcagggtag
     5341 ggatggtccg tactaaacct aaaagaaaac gaaagatggt agaaagaaga cggttttctg
     5401 tcactacagt ggtcgctaaa aaactaacag ggatcgctaa aattaagcca atgaccgttc
     5461 caagcaaaga catttgaagt gttttcacca taggctcgac taatttaggt aaatagctaa
     5521 agtctggatg aatgaagcgt gataaaaaga cagtcatttg attggagttt tgaaaaacct
     5581 gagaaaaatc agctgacgtg atccaggcac ttccttgaaa acaaacaatt aagaacagaa
     5641 gaataagcag gtgtttatac catttaaagt gaacggtttc tttcaagctc atcgatttcg
     5701 cctgcctttt cttcaaagat tgcattgcca taaatttgct ctaagcgttc atcggttaag
     5761 tcgtctggac gaccatcaaa gacaacctga gcagctttta acgcgagcac acgcgtagaa
     5821 aactcacgag ccagagggac tgaatgcaga ttgacaatga ctgttttatc catcgtttga
     5881 ttgatatttt ttaggtccat cataaccttt tgagtcgtga ttggatctaa tgatgcaacg
     5941 ggttcatccg ctaaaataat gggggcttgc tgcacgagtg ctcgcgcaat ggatactcgc
     6001 tgttgttgcc caccactgag ctcatcactg cgtgtctgca atttatcaga caaaccaact
     6061 ttttccagtg cttcctttgt ctgctggtag tcttccttcg taaaaagacc taaaatactt
     6121 ttccaagtgg agtaatagcc caaacgtcca gatagcacat ttttctgaac cgtactacgc
     6181 tttaccagat tgaagctttg cgagattaga ccaatctggc ggcgaatctg tcgcagctct
     6241 tttttattcg cttttgtaat agaggttcca ttaatgcgaa tatctccttt ggtggtttct
     6301 gccaagcgat tgatactgcg cagcagagtg ctctttccag caccactcaa ccctatgatg
     6361 gaaacaaatt ctccatcttc aattgttaag tcaatatcct tcaagccaac aacgccattg
     6421 ggatagacct tcgaaacatt gtcaaaaata atcattatcc ttctccattt ttttaagtgt
     6481 aagcaaaaaa aagcttgctg acacttactg atgttttatt ctgctgcttt tttcgtgtag
     6541 tctctgatcg tgtcataggc agaatcagca gcttcttcat agccctgatg cccccacaaa
     6601 gccattgctt ctttgccatc tttatcatcc ttcatattta agaaggtctc tttaattttc
     6661 gcttttaaat cttttgacat gtcaggctgt acagcgattg cgtcattcgg aatatcgcct
     6721 tttgtcaggt acaggacttt taaatcctta aataaatcat tatctgggaa attcgaagca
     6781 aaaacatttc gcgcgccttc aaaaacaaac gccgcatcca tttgcttgtt caacactgcg
     6841 gtaatctcac tcggaatatc attcacagtg gtcatctttg tatctgcagt aggatcaatc
     6901 ccagcatctt tcaattcagc gacaggatag atgtagccgc tagcagagtt aggacttaag
     6961 gttgcgatat tttttccttt taaatcagtt aacttattca atccgctatc ggcacgaacc
     7021 aatacttctc ctttaaaggt gttcgtaagt ttgtccttta atggcaagcc agtttcttga
     7081 tcataatcgc cgagctgaga agtcaggatt gcatctgcag ctccagcatc ctttgcttga
     7141 acataggctg caggcggcat aattccgaca tcgacttgac cagaagacat cgcttcgacg
     7201 atcgttgaat aatcagtagc taacgtcact tctacctcac gatctaactt tttcgataaa
     7261 tacttagcaa atggttttgc ttttgcctcc atactaccat cattgtttgt tggaacgaat
     7321 tgaacaacta atttttcttt gctctctttt tctgagctgc tacttgtatt cccagaaccg
     7381 caggccgcca aagtggtcaa taacatgact ccgatgaacc cttttgctaa ctgtttgaac
     7441 tgcatttttc tcctcctgtt ggatataatt tctaatacgt ctaaatcata gcagggaatc
     7501 aaaatcaatg aagtgacgca cgtcctattt tacacaactt ttacatacaa tttacaaaca
     7561 attataaata attattcgta ttgagccgaa aaacaatcta agctataata aagaaaaact
     7621 tcttagaggt gacgatttca tgaaaaaaat ccatgatacg aagcaattaa ctgcttacgt
     7681 tgagaagcac aacctgcagg attatatgga ttcagatata ttggcaatgg cttctttact
     7741 tttttttgaa aaggaagagc acctcattca aacgggaaaa acctcagatt atttgtattt
     7801 tttagtggat gggacggtaa tggtgtactc gtattcttct gatacacaaa atatttgcat
     7861 cgattacgca aagcccgcta caccactcgg cgaagcctct tcattgtggg aattatcgcc
     7921 gaaaagcagc gttaaagcag tgactaagtg catctgtatc agcattccgc taaatcaata
     7981 tcgaacacag cttcaaaaag atgttcgctt tttgcagaat atttgccagt tactaagtta
     8041 tcgtttaaat tccgggataa atttggcgaa ctcactgaca gaacctgttg aaactcgttt
     8101 agcaaagttt attttgaccc atcacgaaaa cgaacgtttc tcatttcggt taaccacctg
     8161 cgcctcaatc ttaaatgtca gttatcgaca tcttttacga acaatcacga attttcgtga
     8221 ggagaatatt atcgaaaaga aaaagaatta ttacttgatt catgatatcg aagctttaga
     8281 ggacttagct gagaatataa gtagtccagt aaaagcagaa taacagctat aaaaaaacag
     8341 cagtcagaag tgattgctgg ttttttgata gtggagaaat tgggaaacgg aaaatcttcg
     8401 ttgaagagta gtgttctata tattggtatg ctatactttt aaaagttcaa tgtgtcaaga
     8461 cacataaaaa ggggagaaaa attttgaaga aaatacttgt ttcattgttg tttttggtgt
     8521 cattagtaac gttagtcggc tgtagtcagt ctcaggggga gaagcaaagt gaaaaagaga
     8581 aaagtaaaat cgctttggtt cttggatttg gcggggttga tgaccgctcc ttcaatcaag
     8641 ctggctggga aggattagag gcttggggaa aagagaaaaa gctgacagca aaaaaagatt
     8701 ttacgtatat agaaacgaac aatccagagg ataacagtac caatatcgat caggcaatca
     8761 gaaacggctt taccaccatt attagcttga gctacttgca agcagaggaa ctggaaaatg
     8821 ctgctaaaga taatccaaag ttgaaatttg ccttggtaga tggtgagatt actgggaaaa
     8881 agaatatctc atcagcaacc tttaaagatc aagaaagtgc gtatttagca ggactagctg
     8941 ccgcatatac gacaaaaagt gatcaagtag gctttattgg tggaatggaa gggcccgtga
     9001 tccaacgttt ccaaagcgga tttgaagctg gcgttaaggc aggggccaca gcactgaaca
     9061 aggaaattac tgttaacgta caatatgctg catcctatga ttcgctagat aaaggaaaag
     9121 ctattgctgc ttctatgtac aaagagggag tcgatattct ttatcaggcg gcaggaagta
     9181 ctggagctgg ggtgttccaa gaagcaaaag cccgcaatga aaacgactat agcagaaaag
     9241 tatgggtgat tggtgtagat cgcgatcaag cggatgaagg ggattataaa atggagaacg
     9301 gcgagacagg gaatttcacg ttgacttcta caaagaaaaa tgtcggtgca gaagtcaaag
     9361 aatttgcaga aacttctcat aacgataaat ttcctggcgg caagcatttg acctttggtt
     9421 tgaaagaaga aggggtagat ctgacaaaag gacaattatc agaggaagcc tatcaggcag
     9481 tttcagacgc aaaagagaaa atcatcagtg gtgatttcag actgtagaca aagtccattt
     9541 tatggatgat gtctacagt
//
LOCUS       DAIGSZ010000091         8813 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.094, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000091 DAIGSZ010000000
VERSION     DAIGSZ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.094"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(187..2097)
                     /gene="ltrA"
                     /locus_tag="NOB31_002570"
     CDS             complement(187..2097)
                     /gene="ltrA"
                     /locus_tag="NOB31_002570"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI0974744.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(2867..2980)
                     /locus_tag="NOB31_002571"
     CDS             complement(2867..2980)
                     /locus_tag="NOB31_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HCI0974745.1"
                     /translation="MKRGILMEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
     gene            complement(2977..4161)
                     /locus_tag="NOB31_002572"
     CDS             complement(2977..4161)
                     /locus_tag="NOB31_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCI0974746.1"
                     /translation="MAQRNLDYRLLKERRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     IASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            complement(4417..4706)
                     /locus_tag="NOB31_002573"
                     /pseudo
     CDS             complement(4417..4706)
                     /locus_tag="NOB31_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4696..5838)
                     /gene="dcm"
                     /locus_tag="NOB31_002574"
     CDS             complement(4696..5838)
                     /gene="dcm"
                     /locus_tag="NOB31_002574"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HCI0974747.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDSVAPTLTGD
                     EGIKIALPVKDGISVAGMLSGNFEQGNRIYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKGVKAYDL"
     gene            complement(5883..6149)
                     /locus_tag="NOB31_002575"
     CDS             complement(5883..6149)
                     /locus_tag="NOB31_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HCI0974748.1"
                     /translation="MTSKDYLSLFNFRVALGRMSELGYSMMFGEVDKNFFMKRIKGRG
                     YVDTGGSVISEFYTPLVPKGYDFLREISNIVGLTVHTERENNSV"
     gene            complement(6243..8102)
                     /gene="ltrA"
                     /locus_tag="NOB31_002576"
     CDS             complement(6243..8102)
                     /gene="ltrA"
                     /locus_tag="NOB31_002576"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI0974749.1"
                     /translation="MNKVKTNKTLRHSEYYGMTQIFDELYVKSDKKEVFTELMTIIMS
                     DENIRLAYRNIKNNKGSYTASTDKKSIRDIKTLSEDTFLTEVKVLFRCYKPRAVRRVE
                     IPKPNGKTRPLGIPSIWDRLIQQCILQVLEPICEAKFHNYSYGFRPNRSTHHAIATCN
                     RLANRGKLHFVVDVDIKGFFDNVNHSKLLRQMWTIGIRDKWLLGIIRSMLNAPIVLPT
                     GKVEHPKKGVPQGGVLSPLLSNIILNELDWWVASQWQNTTIETEKIMDRRDKGKGIDK
                     TNQYRALRRTNLKEIYIVRYADDFKIFCRKRSHADKIFHATKMWLKERLSLEISEEKS
                     KIVNLKKGKSEYLGFELKLIKKGKKYVVESHMSKKSMTRVKIQLKKQLRKVARPKNHC
                     EQAKEIGLYNSMVIGIHQYYGIATCVNLDCSKIAYTLKPFINHKLPTKKHGKILNTFI
                     KSKYGKSKEMRWLNNVPIVPLNYVQFRLAVPLSEGTCKYTESGRSKIHSKLKLDLALL
                     LHMMRNSNYERSIEFVDNRISKYSAQKGKCAITGKFLEYEEIHCHHIVPVKQQGTDKY
                     SNLIIIHKNVHALVHAIEEKIIHKYLNVLNLTNEQIEKLNELRVKAGNSVLTV"
BASE COUNT         2324 a         1906 c         1441 g         3142 t
ORIGIN      
        1 ccaatgacca caatcgctag taagactaaa gattgagcat tggttaaaaa ccattgatat
       61 atggataggt aagttcctga tattataaat atctcaaact tttcccccca ttcacacgga
      121 gcgtgcgact ttcaccgcac tccgcgttcc atcgtgttta tattgaaaag tatttatgta
      181 gtagacctat atcaagttta attcttgatt gccagctaat actctatatt tatttagtct
      241 tatgagctgg actttattta gcttcaatag agctatatat ttttgtattg tttcttctgt
      301 tttagcgtgt attagacggt gtaccgcctc ttttaccaaa ataagatttt tataatcgtc
      361 atttccacca gctccagttg gtacaatatg atgacaatgt atttcattag cttgttgaaa
      421 ttcttccaga gttatagcac attttccatg ttgagcagaa aatagcgaaa ttcgattgtc
      481 tgcgtattct attgtgcgat tttccaaaga taatttcatt aactggtaca tcagtaattt
      541 atcaacactt agattggtgt ggataaattt tcttccctct agagtgtagc aattcgctaa
      601 atacaccttt gccattggtt ttctgtgttg gatatatcca acagggaaaa taggttcgcc
      661 ctcgccagca acataccgaa gcattttaga tttaccatat cttgttgcct cctttgtcgt
      721 aagttgtctg cctgtttttc tcaatctgcc ccttttgttt gtacctaatc tgttagtgaa
      781 gatagccatt acagctctat tcagtttcat acaatccaga tttacattcg ttgcaatctg
      841 ataataattt tgcataccta ataccattga attataaagt cttgtttctt ctaattccgt
      901 tttccctttt gagggagaag caattttctt tgcctgtgat accagcttgt ctttttggtt
      961 tttgaattgt ttatcactta tatgtgattt aacaactaac ttctttcttc tcggtatcat
     1021 tttaatcttg aaaccaagaa agtcggagta tctttttcta acatttacaa ttcttgtttt
     1081 ttcttgtgat acttccaatt ttaatcgttg ttcaatccat tgagtgattg ctattttggc
     1141 tttttcagca ctttccttgt agcggcagaa aactctaaaa tcatctgcat aacgaaccat
     1201 atacatttcc tttaactttg ttttcttcat ttctttgtaa gcgttgcttt tacatgggct
     1261 accgctttta ttgatatgaa ccacatagtt ttttgtaaca ggattttcct gccattggct
     1321 ttctacccaa tggtctaact cattaagaac aatgtttgct agtagtgggg atattattcc
     1381 cccttgcgga gttcctttct ctggatatgt tattgtaccg ttagtcattt tgattggagc
     1441 ttttaatatc ctttttaaaa tgaatatcaa gtgcttgtcc cgtattccca tagcccatat
     1501 ctgttttatc agcttggaat ggttcacgtt gtcaaagaaa cccttaatat caaattcaat
     1561 cacataatgt agctggctga tttgtaggcg gttataggtt gcttttattg cattttcaac
     1621 tgacctatta ggtctaaaac catagctgtt ttcactaaat ttagcttcgc agattggttc
     1681 taatacttgt tttatacatt gttgtataag cctgtcccac atacaaggaa tacctagagg
     1741 tctggtttta ccatttggtt ttggtatttc ttttcgcctc actggcttag gtcgataccc
     1801 atgtggactg cctgcaacaa tgtatcttac ttttttgaca actgtttctg ctggcaattt
     1861 gccaatatct ttaattattg taccgtctgt tcctgctgtt ttactgcctg catttgcttt
     1921 gatatttcga tatgccagta atatattttc tctcgatagg ataatatcca taagatgagt
     1981 gaaaatatct ccattcttac ttttggcata taaatcatca aaggtgtttt gcatttcgta
     2041 atattcagcg tgtcttaaat cttctacaca caatgtttca tttttatttt taggcataag
     2101 gcttcactcc tttacttgaa attgagtgag cttttttatc ttactcgtaa tccttattga
     2161 aacaacataa tacttttcta atatatacac gacttgaggg cattcctcca ttctcattac
     2221 aagaatttct taggttcgcc ctctgctttt cagcattagt tcaactgctt attgttcttc
     2281 gtcagtttat tctcttgatg agaacccaat acctttcctc gttccgataa tcttatctat
     2341 acatatatat ccttaggtca ctagctataa gcctgctggc ttgataccgc ctgtaacgtt
     2401 atatggcatt tcataaccta tattcttact ttgccacacc agctacgatt tctcgtacct
     2461 ttgcatttct acaaagttca aatttagacc cgtacattcg ctgtttcgtc agttccttat
     2521 agaacattct aaccatagat attttataga cccccgacct gttggatacg ctacccacct
     2581 ctggatagtt ttcgatagaa gatatatgtt catcaactat tacggtatct ttcagccgtc
     2641 tttaccgagc ttcaaacatt ctgagtttcc tcatacaatg cttgtcggag gctcagggca
     2701 ggcgtttcag agcgttactt catcattcca cctgtcagat tatcagttct cctaataacc
     2761 aaactttttc gttcttttat tagtgcctta gcttttcact aaggaacgag tcgcacataa
     2821 attttgtccg aaattcattt tgtcactttc ctttcttttc cattgctcaa tccgctgctg
     2881 cacttgcatt catcaagcac atcacggtaa caccaagcat actgccacca agtaccaata
     2941 acatatcttt tacaatttcc atcaaaattc ctcttttcat acaatcaagt tttcgattgc
     3001 catactttgt tgctccaaaa tctttttatg ccggtccgag agtcgcgcat tctgtaccat
     3061 atcctggata tacgttgttt gattcaatcg atccaactcc ttagccattt tccacgtagg
     3121 ggcgacttgt ctacctagcc aatttaatgt tcgttcaatg gtatacggtt tcggttcaga
     3181 agttaattga atctctttcc gattccgtcc aataaaacga ccccattgtt cattcaaggg
     3241 ccaattggtt cgccgttttc catctacttt atccgcaaat cgcaaatacc gattgataat
     3301 ggaaaacgtg gtactttcaa tgctacgacc ttttaacaaa tcttgaatcg cataataagc
     3361 acggtcattt ttcaaccgaa tctcaaaacg atttttcgtt tcggtctggt ccaatggaat
     3421 ccctaacttg atatattgtt cataatcttt ttcgtacaaa caaaaataaa cctcgctttt
     3481 gaggctgcca atatataagg tattgcccat accatccttt tcatcagctt tcaacagttc
     3541 cccggaacgg taacttttga aggtacgaaa caaggagata cattcttcct tctgacattt
     3601 tttcgttaaa tcaggaatat ccagtagccc cactcgatca ttgattgcta aatccaagcg
     3661 tttcatcacg ccaccggctt ttagacaatc ttcaaaaaag tcgtaccagc tacgcttttg
     3721 ggcgagtaaa aaagtttcaa actgccggca accacgacct tttaattcca aaaggacacc
     3781 tttatcttct tcatgagata acatcactac aatatcgccc atgacatatt gttcttgata
     3841 ggagtaaaag gcgtaatctt catgaagcat atactcgaat ttcaaatgga gaatttcttg
     3901 aataattttc cgcacatccg ttgtgggaaa gcgaatcctt acatagtcaa atagtaacgt
     3961 taaaggtaaa tcgggattga aactttccag ttgatcaaaa atttttctca tggtctttgt
     4021 agaggcgatt acgccaccgt tttctatctg atttaggtat gggcggctaa gtccgcaagc
     4081 agtagctaat ttattttgtg aaacgccata ttcgttgcgt cgttctttta ataaccgata
     4141 atctaaattt cgttgcgcca agttttcacc tccaaattca aggtgttaac ttttccaaat
     4201 gagttaacac ctatacaaat tacttaatat ccttgataca acaagcattt tttatggtta
     4261 cttgcttgtt ttttgtgttt ttgtaccccc ctgttagata cggggggtga gacatcatgg
     4321 ccggctgccg ccgtccatga acaggcacag caccacggag gatttctgct tcgcaaatcc
     4381 cccgcggtca gtgcctatca gtgggttatt tccctattac tccgcggtga taccctcaat
     4441 ttccaactct gcttttatct caaacaagta ttggcggata tcaggttctt tggcaaggtc
     4501 cgcaattcgt tccaattcac cgatgacttg attgagctcc attcgagcat ccgtttcctc
     4561 atccactaca tacgaatcac ctggactttc accccgtttt tgcgaatatc aaaattgagc
     4621 cggtacagtt cttcttccaa tttcggatct gcctgaatct tgccaatcat ccagtagatt
     4681 tctccaatca actcgtcata aatcatatgc ttttaccccc tttaatcttc tagcaatatc
     4741 aaaaatgacc ggaactgtta ctgagtttcc ggcctgttta tacaactgac tatctgaatt
     4801 gacttgagaa gctcgatcaa aagcccaatc tggaaagccc tgaagccgcc agcactccct
     4861 aggtgttaac tttcgaatct ggtactgatc cgtgactacc gcttgttggt ctcctgttag
     4921 taaggtatgc acactttgtt ttcccagacg acctcggcga cttgtggaat taggaaaagc
     4981 caggttcaca ctgtcccctg gcttcacctc ttgatattct gtttcatttt tccgaatcat
     5041 aatcttcgtt cccccttgtt tcgttgacaa agtgggggct gttccggtta cctcataaat
     5101 cctattgcct tgttcaaaat ttcccgacaa catacccgct acagaaatcc catcctttac
     5161 cggtaaggca attttaattc cttcatcacc ggtcaaggtt ggtgctacgc tatctgaacc
     5221 atagacttgg ccacccattc ctcgattgga aggattgata tttaccaagt ttctgatgtt
     5281 ttgatcagat gttgaagacg atccaatgat aggaaatact tgttcggtac atgcatctcg
     5341 agaatgtccg ataaggaaga tccgctcacg gctttgggga acgtaggcct ttgagttaag
     5401 cacttgccat tccacatcat accccaatcc atccaacgtt cggaggatcg tctcgaacgt
     5461 agcccctcct tcgtgattga gcaatccccg gacgttctca aggaatagaa acttaggttg
     5521 gagaagagtg gcgaaccgag cgatttcaaa gaataaagta cctcgagtat cggaaaatcc
     5581 ttgccgcttt cccgcaattg aaaaagcttg gcacggaaag ccgccgcaaa ggatgtccac
     5641 tggtccgagg gatcgaacaa attcgtctga tacacttgtg atgtcatgca tttccacctc
     5701 cttccttgta tcatggattg ctttataact cctccgagca aattcatcaa tttcacaaaa
     5761 accgatacac tggtgaccgg cttgttccat acctaagcga aagccaccaa tcccggcgaa
     5821 taaatctaaa aatgtcataa atcacctcaa taaaaaagcc caggattatt gatattccta
     5881 ggctacacac tattattttc tctttccgta tgaacggtta atccaacaat gttgctaatt
     5941 tcccttaaga aatcataccc ttttggtaca agtggcgtat aaaactcact aatcacactg
     6001 ccccctgtat ctacataacc tcgtcctttg atgcgtttca taaaaaaatt tttatcgact
     6061 tctccaaaca tcatggaata cccaagctca ctcatacgac ccaaagccac acggaagtta
     6121 aatagcgata ggtaatcctt tgatgtcatc tccagatttt cccccgcttc acaccgtaca
     6181 tgaaactttc acttcatacg gcgttccatc aaaagaatgt taagtatgat atatttttca
     6241 agttaaactg ttaaaacact attaccagct ttgacacgta attcatttag tttttctatt
     6301 tgttcattgg ttagatttaa tacattcagg tatttgtgta tgattttttc ttcgatagca
     6361 tggactaatg cgtgaacatt tttgtgaata ataatgaggt tgctgtattt gtctgtaccc
     6421 tgttgtttta ctggtacgat atggtggcaa tggatttctt cgtattcgag aaatttaccc
     6481 gtgatagcac attttccctt ttgagcagaa tatttagata ttctgttatc cacaaattca
     6541 atacttcttt cataattact atttctcatc atgtgaagta aaagggctag gtctaatttt
     6601 aatttactgt gtatcttgct tcgtccactt tcagtgtact tgcaagttcc ctctgatagg
     6661 gggacagcaa gtctaaactg aacatagttg agcggtacaa ttggcacatt attcaaccat
     6721 cgcatttctt tactttttcc atacttcgat ttgataaatg tatttaatat ctttccatgt
     6781 ttctttgtcg gcagtttgtg attgatgaac ggttttagtg tataggctat tttactgcaa
     6841 tcgagattta cacaggttgc aattccataa tattgatgga ttccaatcac catagaatta
     6901 tataatccaa tttcttttgc ttgttcgcaa tgattcttcg gtctggcaac tttacgtaat
     6961 tgtttcttta attggatttt aactcttgtc attgattttt tgctcatatg actttcgact
     7021 acgtattttt tacctttctt gattagcttt aattcaaatc ctagatattc tgatttacct
     7081 tttttgagat tgacaatttt ggatttttct tcgctaattt caagtgataa ccgttcttta
     7141 agccacattt tcgttgcgtg aaatatttta tctgcatgac ttcgttttct acaaaagatt
     7201 ttgaagtcgt cagcataccg aacaatgtat atttctttta agtttgttcg tcttaatgcc
     7261 cgatactgat tagtcttatc aatgcctttg cctttatctc gcctatccat aatcttttct
     7321 gtctcaatcg tggtattttg ccattgtgaa gcaacccacc aatctaattc attcaatatg
     7381 atattagata gtaaagggga taggacacca ccttgaggta cacctttttt agggtgttcg
     7441 actttaccgg ttggtaggac tataggagca tttagcatgg atcgaataat acctaatagc
     7501 catttatcac ggattccaat cgtccacatt tgacgcaaaa gtttagagtg attgacatta
     7561 tcaaagaatc ctttaatatc aacatctact acaaagtgta gcttccccct atttgccagt
     7621 cgattgcagg tagcaatcgc atgatgtgtg gaacggtttg gtcgaaatcc ataactataa
     7681 ttgtgaaatt tagcttcgca tatcggttct aagacttgta aaatacactg ttgtattaac
     7741 ctatcccaga ttgatggaat gcccagaggg cgtgtttttc catttggttt gggaatttct
     7801 acacgtctaa ctgctcgtgg tttgtaacag cgaaaaagaa ctttaacctc agttagaaag
     7861 gtatcttctg acagtgtttt aatgtctcga atacttttct tatcggtact cgctgtataa
     7921 ctgcccttgt tattcttgat atttctgtat gctagtcgaa tattttcatc actcataata
     7981 attgtcatga gctctgtaaa aacttctttt ttatcacttt ttacatacag ttcatcaaat
     8041 atttgtgtca tgccatagta ttcactatga cgaagtgttt tatttgtttt tactttattc
     8101 atagcaccac tacctttgtt tacttaggtt gtagtgttta ttttgtctta ctcgattcta
     8161 tgaaatacat catttaatta acgatttctt ttgactagtg gctattcctc cgatatattt
     8221 ctatatcctc attggtactg tgccaccact ttcactggca taaatgtgct tattattctt
     8281 cgtcacaaat gtttcaatgg aatatagttt cctccacatt gccagcttcc catgtttcga
     8341 tatttttatc tttatatata cttttaggtg cttgctttga acctgtatat ttccaatgcc
     8401 tgtaacattg catggttgtt cataaccaat aatcttacta aaccacaaca tacattctgt
     8461 tccgttgata cggtagaatc ctgtacattt ctatacagtc cgtgtataga ttctttcatt
     8521 cgcaagttcg tcagtagtat tacttacatt ctcaccgtga gtattttata gacctccgac
     8581 ctataggtta catcattcac ctctgaacaa ctttcgtata tgaatttatc atatttacgg
     8641 taactttcag ccgacttcac cgagcttctg accatctaac agctatatgt taaacagcca
     8701 gtcggagtat taagggagcg tttcagggcg ttaccccatc attccactgc tcaaaatatc
     8761 agttctcctt aaaaggaaac ttatgttttc ttcttttaag tgcctaacct ttt
//
LOCUS       DAIGSZ010000092         8573 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.095, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000092 DAIGSZ010000000
VERSION     DAIGSZ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.095"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(45..1498)
                     /locus_tag="NOB31_002577"
                     /pseudo
     CDS             complement(45..1498)
                     /locus_tag="NOB31_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
     gene            1885..2481
                     /locus_tag="NOB31_002578"
     CDS             1885..2481
                     /locus_tag="NOB31_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI0974750.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(2539..3021)
                     /locus_tag="NOB31_002579"
     CDS             complement(2539..3021)
                     /locus_tag="NOB31_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974751.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3127..3324)
                     /locus_tag="NOB31_002580"
     CDS             complement(3127..3324)
                     /locus_tag="NOB31_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974752.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3619..4377
                     /locus_tag="NOB31_002581"
     CDS             3619..4377
                     /locus_tag="NOB31_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HCI0974753.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4437..4865
                     /locus_tag="NOB31_002582"
     CDS             4437..4865
                     /locus_tag="NOB31_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974754.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4911..4983
                     /locus_tag="NOB31_002583"
     tRNA            4911..4983
                     /locus_tag="NOB31_002583"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4944..4946,aa:Gln,seq:ctg)
     gene            complement(5133..5504)
                     /locus_tag="NOB31_002584"
     CDS             complement(5133..5504)
                     /locus_tag="NOB31_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCI0974755.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5719..5904
                     /locus_tag="NOB31_002585"
     CDS             5719..5904
                     /locus_tag="NOB31_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974756.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(5987..6175)
                     /locus_tag="NOB31_002586"
     CDS             complement(5987..6175)
                     /locus_tag="NOB31_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974757.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6199..6462)
                     /locus_tag="NOB31_002587"
     CDS             complement(6199..6462)
                     /locus_tag="NOB31_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974758.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6620..6877
                     /locus_tag="NOB31_002588"
     CDS             6620..6877
                     /locus_tag="NOB31_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HCI0974759.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6948..7139)
                     /locus_tag="NOB31_002589"
     CDS             complement(6948..7139)
                     /locus_tag="NOB31_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974760.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7280..7600)
                     /locus_tag="NOB31_002590"
     CDS             complement(7280..7600)
                     /locus_tag="NOB31_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974761.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7623..8057)
                     /locus_tag="NOB31_002591"
     CDS             complement(7623..8057)
                     /locus_tag="NOB31_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCI0974762.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8392..>8573
                     /locus_tag="NOB31_002592"
     CDS             8392..>8573
                     /locus_tag="NOB31_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCI0974763.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2715 a         1692 c         1357 g         2809 t
ORIGIN      
        1 aggaactgct gcaaataagc aattcctgtt tttatgttca ttgattaatg aatagagccc
       61 attagttttt tgattggttc tttcacagta aatagcaaga taccaccgac gattgctact
      121 gcaccgataa taccgaagta agcagattct gttcccggtg tgtagaagcg tgcaatttgt
      181 gcattgattg cttgtgaaga agcatcagct aagaaccaaa tagcgattgt ttgtgattca
      241 aatgctcgtg gtgctaattt tgttgtcaca gacaaaccaa ctggtgaaag acacaattca
      301 gcaataacca cgatgaagaa acttcccaac aaccacaatg gacttacttt tccacttgta
      361 ccataaagca tacccggcaa catcaatagc aagtacgata atcctgcaaa taaaagtcca
      421 agagagaatt tcactactgt agatggttga cgttcaccaa gtttcgtcca catcgttacg
      481 aatactggtg tcagaataaa gatgaaaatt ggattcaatg attgatacca gcttgcttgg
      541 atcgttacac caaatagcgt agattgtgta cgttcactag caaataaagc taagatagat
      601 gaaccttgtt cttgtaatga ccagaaaatg attgctgcaa ggaataatgg gatataagcc
      661 catactcttg gtttttcttc agcagttaca tcttttgaag tcagcatttt gataaagtaa
      721 tacaacggta agataatccc caatacactg attgtattga caaaaaagtc aattgtcaga
      781 tgaccagtta gttgtgcccc gccgaatact gcagcgataa caacaagtgc gatgatcaag
      841 ttacggatga atcctttacg ttcttcagtt gtcaaaggat tcggcggtgt tgtacccact
      901 ccgtctaatg tcttgcgtcc ttggatgatg tattgtaata atccaaagaa catcccaata
      961 gcagctaaag agaaccctaa atgatagtta tattcttgac cgattgtact gctaataatg
     1021 cccctaagtt gacacccatg taaaaaatcg aaaatcctgc atctcttcgc aagtcagtct
     1081 ttgaataaag atgtccgacc atgccagaaa catttggttt caaaaaggcg gttccgataa
     1141 taatcaatgc catcgaaaca aacaatgtac ttacaccaaa tggtaaagcc aagacgatgt
     1201 ggccaagcat aatgaaaact ccaccgaaga atacagtgcg ttttgctcct aacactcggt
     1261 cagataccca tccgccgacg atactagaca tgtagatcaa agatccgtag atcgacatga
     1321 tagctaatgc tgttgctcgt ggtaatccaa gtcccccgtt ggcaactgta tcgtacatat
     1381 aatagataag taatgcacgc ataccgtaat aactaaatcg ttcccacatc tcagtgaaga
     1441 acaaagttga caatcccttc ggctgcccga agaagccctt gtcttgctgt ttttccataa
     1501 tctatacccc aattctttaa attttcagaa aatattatac atctttaccg aaaaatttaa
     1561 ctaaaaaact tatttaagaa atataaacta attttctata aaagcaagta atttttaatg
     1621 gcaatatcat aaaaaaaaga agatagagat ttaataatta tatatcagct gtttttttca
     1681 aataagcaaa aattcctaaa acacaacaat gaaagcgata actaagaaaa tccttacata
     1741 acgatttttc ttattaaaat tgttttttga acttcgctta ttttttgtga gcatatctgt
     1801 ttacttactt tttgtaaggt gctatacttc atttcgtaat caattaaaaa aatgcaaaac
     1861 gcaaatcaaa ggagaaattt tattatgaca acttttactg acactttgaa aaaccgccgt
     1921 tcaatctatc atctaggacg taatgtttca ctttctaatg aagaattaac aactttgatc
     1981 aaagaagcaa ttaaagaaag cccaactgct ttcaatgctc aatcaacacg cgcagttatc
     2041 cttttcggag atgcacatga aaaactttgg gaaatcactg aagaagcact tcgcccattg
     2101 actccagcag aagctttccc aaatacacaa aacaaattag ctggtttcaa aaatggttat
     2161 ggtacagtat tattcttcaa agatactgac gtggtaaaag gtctacaaga acaatttgaa
     2221 ttatatgcag acaacttccc agattggtca gaacaatcaa acggaatcgc aacagctaat
     2281 acttgggtag cattagttga taaaggattg ggcgcaaact tgcaacatta caacccagtt
     2341 attgacgaag cagttgcaaa agaatggaat atcccttcaa actggaaact acgttcgcaa
     2401 ttagtattcg gttcaccaga aacaccggct gaggaaaaag aatacatgaa cgatgccgat
     2461 cgcttccgcg tatttggata attttatttg aaataaaaaa cagaggttgt gacaaacatc
     2521 ttgtcgcaac ctctgttttt attctggatc aatcataata tcaatctctg cctcatcgtt
     2581 taagcgttgg gacaaaaatg gaactaattc ttctaatgat gcagaaaatt tcagcatcgg
     2641 tcctcgccat ccgtttcgga aaaaattcat ttttacgatt ttagaacctt ttggctgata
     2701 taatacaatt ttattgatct cagaaaaagg aacacctttt ttgtcaaagc tattcaaaac
     2761 aagtccttct tctgtgattc ctctactgtc caacaaaaaa ctaataaaaa tcattgctga
     2821 caagatccct tttgccaatt catctgctgt aggatgactg atgagtgtat accaaatgac
     2881 tagtgacact aagaagggta tcaccaagta gacccatcga tttcgcacag tccgataaat
     2941 aatttctttt cgaaccagcc aaagaaataa aaacatcaca acaacgaata aaaacaatag
     3001 aaccgtaaag aatgttacca tgacaactcg cctcgctttt tcttctccag aaaataggaa
     3061 aagaatactg atttaccttc tcaaagaaat tggacttgca gcacgccgca cgtccaattg
     3121 ttttctttat tcaaatgtat catattttgc aacaaccatg cttgcttttt catctaataa
     3181 ttcttggtcc tctgcagcac attgggcaac tttgaccacg gcgcagtttg tcatttttga
     3241 tacaacttca ccaatgaccg tttttgtaaa accaattggt ttgcatgcat attgttctcc
     3301 taaattaatc atttcttccg tcatcaaaat cctcctaaac tgctggaact tttctccaca
     3361 ttaccactgc tatttctttg gagatttaac tcattgattt ttatttacag ttaaaaatca
     3421 accttacagg cattatagcg tactgttttc gttttcacaa ttaaaacagc tgttgtattt
     3481 agaagaattt ttttcaaaaa attaaaacat attccttaaa aactaattat ttcctacata
     3541 ttaaaatata atacttccat ttccaataaa aatacattta taataggaaa gataaacagc
     3601 tgaaaaggga gatttcaaat gaagaaaaaa acgttcaaaa aactattgtt tctagggggc
     3661 acagctgctc ttttattaag cggtacaagt tattacctac atatccattc tccagaacat
     3721 acaatgaaca ctgcacaaaa aagttcaaca caaaaaacga aaaagacaaa agagaaagca
     3781 gaagttttac tagatgttcc attagagagc cagtttgatt ctccttcttt agaaaatggc
     3841 tgtgaagtca cttcgctttc tatgctttta tctttttatg gttatgaaac aactaaaaac
     3901 cagttagctg agcaattgga ttacgtccct gttttcaatg cagatgggac tcatggcgat
     3961 cctaatgaag gatttgttgg tgatatcagt ggcggagact gggctatggt cgtctatgtt
     4021 cccccagttg cctcccttgc tcagcaaatc gtccaaacgg attatcacac ttttccaaaa
     4081 accgatgctc aactcgatga tatcaaaaaa gcactatcta aaggaaatcc tgtctggact
     4141 tctgtgacta tcaattttga agtcccagat gaaactgatt ttatgacttg gaccacaaat
     4201 aatggagaag taagagtcac tcctcttgtt catgcttgtg tagtcactgg atatgacaaa
     4261 gaaaatattt atgtcaacga tccctatggt gtaaaaaatc gagcagtacc gatcaacgat
     4321 ttttcggcga ttttcactgc aatgggtgga cagatgctaa ctttggagaa aagctagtaa
     4381 ttcaaacaaa aatcccttat actcaagata ccaaaccttt gaagggagcg tagataatgg
     4441 aaaaattcac acataaaaaa atggatccaa atgaaattcc gattattttt gtccgtgact
     4501 gcaagggaaa tgttcaaggt aaagtctcta ttaatgagtg gaacgagcgt cgcagacctg
     4561 ctaccctcaa tgaactggaa atcaaattgt atcgtcaatc tcttgtttat tacgcagatc
     4621 aagagtacga gaaagccacc gatttattga aatttctaat tgctcgaaca gagtatactc
     4681 gctttgaata tattgaacgt ttagcaaaca tctatcatat tatgaatgaa cctgtcaaag
     4741 aatatcagtt attggacacc gtcttgtcag tagcagaact gattgccctt cctgctggat
     4801 tagaaaagaa actagtacgc cgccttttac gagtaaagca acaactatcc gatcaagaaa
     4861 aataacttgc gtttttttag gaaagtgcta tgattatttt gttgaataaa tgggatgtag
     4921 ccaaactggt aaggcacttg actctgaatc aagcaattgt aggttcgaac cctgccatcc
     4981 caatttgatg tgcttgctga aaaaatgaac cccctgtaaa agaacaatct ttttgcaggg
     5041 ggattattgt attattttta ctacttgtat ttagtttaca taattaaatt atgaataata
     5101 aaatcgggcg tattcttaat acaaaaactg atttacccaa taattgctaa tgctttctcc
     5161 ggaacttttt ctctaggaac ttcctcatac gtttctatgt gtgctccttt attgctaatt
     5221 ttcaaataat gattttcttt taacacagaa agaccattaa attcaaccgt tcgttctttc
     5281 ccattggcat cagcagcttt ctgcacatac cttgctgtac catattcatt tacttcctct
     5341 ggtttttgtg tctttacata gacctctcct ttttcaacta atggatttag ctgatcaagt
     5401 ataccaggga tttctccata acttccttca gtataatatt tcagtccaaa tagcaaaata
     5461 ccactaatcg ccgccagtcc aatcaaatat ttaatcactt tcatctttct acctccttgt
     5521 tatatattca gtatatgggt cagttaaaga aattccatcc gtcccaagtt ggagattttt
     5581 ctcctacttt agaagcgaga atcgagtgtt tttttagtaa aaatgatcgt tatttgatat
     5641 tattgacgtg tggataaatc agtttttctc gttttgtcca tgtaaaaaat catgttgata
     5701 gcaaaggatg tgttcaaaat gaatcaagaa gaattatttc aaaaagtcaa ggaaatgatt
     5761 aagaacggca atttcgatgg cgcaaaacga tttatcgaag aacataaaga acaattagga
     5821 ccttataaag agaaagccca aaatctttta aaagatgtaa atatcgacag tgtcaaaaac
     5881 aaatttaaaa atctattcaa ataagtaaaa ctttcacttt tgtaaaatca aaggaggaca
     5941 atgctgctgc atcgtcctcc tttggttctt ttctgaatac ttcatactaa aataaacgtg
     6001 tcggatcgta atgataagtc acattgccgt tcagtgaggc ttttcccacc acatatttac
     6061 gattctccaa cttcagccac gcttctcgaa aagccattaa ttcttctctt tttacatcaa
     6121 tcttttcgat ttttccatcg atcaaatctt gaataagttg ttcatatgga ttcatttttt
     6181 tcctccatct gctgtcaatc aataagttgt aaaaataggt tcatatgctt ttttggtatc
     6241 tagatcttct ctgactttga ctgtcgtata aataattttt tctactggga tactataata
     6301 acttccttca ccattattga atcggtgaac gtctttcttt gctaaaatac catttatttt
     6361 attcgtcagt acacgttgtt cgacactgtt acttacaaca tagtaaatca cccgaatatt
     6421 attgatcaaa tgcaaatcga tttctaacac tacatgatcc atgaaaatcc cactccttct
     6481 ttcactttga ttatagcaag tttctcctct aatttcaaaa tcgatacaga ttttaccgga
     6541 taaatccaca aaactgcttg cgccatttcg cacaaagtgt tattttgtat catggacttt
     6601 atttatcgga ggcaatagta tgatcgcgat cggtcaattt gttttttata ttcctttttt
     6661 tattatgata agcattcttt tctattacat aaaatggaca aaaaagaagt tttcagtttt
     6721 actggcctct ttacctgctg tatattttac ttatcaaatt ttttctttta ggcattggga
     6781 aacaacgtct gtattaataa cacacatcat cgaattgacg ctttcagtaa tttttcttat
     6841 tatttggatc tattttttat ataagaatca gaattgaatc cctcgcatgt ttaaaaagaa
     6901 aacgattaaa gatgcagcaa atttctgccg atctttaatc gttttttcta ttctgttata
     6961 ccaaaaaaat gtttgaatcg gtgaaggatc gttccttgtt ttaattctat aaattcttgt
     7021 gcgatcgggt acttttcttc caaattttct ttgttctttt cgatcaggct tttcgcttct
     7081 tcatattttt tatctgcaca tagtgctttt acttcctgta atacttttcc tgcttccatt
     7141 tgcctcaccc tcttgccatt ttattgcttt aagttttatt taagttatac gcattattct
     7201 agtttcatcc caaataacct tttttcattt ttactcctcg aactaatcag ttttctaaag
     7261 gctgattggt tcgtcttttt tatttttcct ccatttcatt ctgctcttct gttaatttat
     7321 ctaatgcttt gattgatgct gcggctcttg cataatcata gctgtataat tccataaatt
     7381 tatcaggcag aacaaaccac gctggatgat aaccgttagc tgtgacaggg aatcctttat
     7441 cttgttggtt atctccatcc catctcagag caacaccttt ttttcctttc cactttacta
     7501 aagcgatcga gtatcccttc tttgtttgtg tgccgtcttc aataattgct aaaatttcta
     7561 ttttttcttt tggcgcacgg acttcttgag gacgaaccat tttctattcc tcccttatct
     7621 cattacttca cgaccaacac actgcaaggg gcatgtgata cgacataaga agcggtcgat
     7681 ccaactaatg cttgttgtat agcacctttt cctgtcgctc ccataacgat caaatcaata
     7741 ttttcttgtc cagggatgac attggcaatc aaatttcttg gatctccagt ttcaactatt
     7801 gcgtggatct cagcaatgcc gtactctttg gcatcattga tttttttcag catggctact
     7861 tctgttcttt gtttttcatc tgcatagatt tttgaaaagg cataggcact atgggtcagc
     7921 tcaactttgt tgatgattga cacgataaat aagtgggctt cattgtcctt tgctaagtca
     7981 agggcttcag cgaacgcttt gatcgattgt cttgatccgt caactgctac catgatgttc
     8041 tggtatcttt tactcattgg aaccgcctcc tttttctttt attgtaacat ctcaagcaaa
     8101 aatacaaaaa atatacgcaa tatgtaaata aaatgatgaa caaaagcaat ttctttcaag
     8161 ttatttatac atttcttttc tcatcagaac acctgttcta atcccattat ttctgcatta
     8221 tgtgaaattc ctcatcattt ttcacatcga gcgaacatca ttctgttaca aaaaacgtgg
     8281 atttgtcata aattgtcatg cttcttttac ctatgaaata ttttcacgtg ttaaagtatt
     8341 cctcgttgaa cacaacaaat aaaacttttt aacgaataaa ggagattttt catgacatca
     8401 cttaaaactt tactttttgg aacaactttg gctgccggcg ctgcattctt catgggaacg
     8461 actgctcatg cggacgaagc ttataccgtt caatcaggtg atactctatc aacgatttct
     8521 caaaaatacg ttggtgataa ctccttgatc aatgccattg cagaatcaaa ttc
//
LOCUS       DAIGSZ010000093         8492 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.096, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000093 DAIGSZ010000000
VERSION     DAIGSZ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.096"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..172)
                     /locus_tag="NOB31_002593"
     CDS             complement(<1..172)
                     /locus_tag="NOB31_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0974764.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(592..1713)
                     /locus_tag="NOB31_002594"
     CDS             complement(592..1713)
                     /locus_tag="NOB31_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HCI0974765.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2041..3450
                     /gene="istA"
                     /locus_tag="NOB31_002595"
     CDS             2041..3450
                     /gene="istA"
                     /locus_tag="NOB31_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HCI0974766.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3447..4175
                     /gene="istB"
                     /locus_tag="NOB31_002596"
     CDS             3447..4175
                     /gene="istB"
                     /locus_tag="NOB31_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HCI0974767.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4303..5214)
                     /locus_tag="NOB31_002597"
     CDS             complement(4303..5214)
                     /locus_tag="NOB31_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0974768.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5231..6238)
                     /locus_tag="NOB31_002598"
     CDS             complement(5231..6238)
                     /locus_tag="NOB31_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCI0974769.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6235..8364)
                     /locus_tag="NOB31_002599"
     CDS             complement(6235..8364)
                     /locus_tag="NOB31_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCI0974770.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8369..>8492)
                     /locus_tag="NOB31_002600"
     CDS             complement(8369..>8492)
                     /locus_tag="NOB31_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0974771.1"
                     /translation="NGQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2598 a         1728 c         1486 g         2680 t
ORIGIN      
        1 ttaaaaagtt agtaaataat tgccctctaa gttccacggt ctgttcatta ataactttat
       61 atcctcgttt ttcaaaaaat ggctttgcgg taatggaagc gtgggtagtg attttttgca
      121 taccagtttc taaaacatgg ttttccaatt catctgcaat tttagtcgca ataccttttc
      181 cttgatggct atgtttttgt cacaacttca gtattcctgt aacaatacgg atttcagtat
      241 acaacaacag cttttgaaaa gatacttgca aaaggattaa gatatctatg acctgctatg
      301 ctcactgatg ttgaaaagaa tgttttatta ggattgaggt aagcaagata gtgaatatgt
      361 ccggaaagcc tgtaaaataa ggcttttcgg acatatgtga agttataaaa agatagcgaa
      421 aaatctattt agtatcacta atgttgcgaa catatcgtca gaatagtctg acatttattt
      481 cttgctaaaa atttcaaaaa agtcaagtgc tgacgcagcg gatgactatt ttccagaaaa
      541 ttttagtatg tattcaaaaa tcaaacgtga caacagctat taactacatc ctcatccagg
      601 tctgtaacgt ttgaaccact cttctgcggg ctcaaacatt aagtaatgga aggtacgttt
      661 caattgaaac agcgtcgctg tcgtattcaa ctcaattttt atcacataag tgagaagcgt
      721 tgcgattaag gtgaggatga cttgatttat cgccccttgt tcactatgtg aatatagtcg
      781 tttaatggtc agattttgtt ttaagtgttt gaacaacaat tcaatctgcc aacgggcttg
      841 atacatgtcg gccacttcgt ttggcgatac atcaaagaga ttggtcacca ttcgcaggat
      901 tttttgtccc ttggtaagaa ccgttaccaa cctaaaacgc tctgtcacat ggttgacacc
      961 gccgacaaga atcacttgtt ggtcactgat tatcgtccca tcacgggttg ttgtatctgc
     1021 tacttcaatt tgatccaaga tggtaatttt tgtattagat tttgtccgtg taacgaagaa
     1081 atagccgtca cgatttagtt tgtctaacaa cttgtaatca aagtagccgc gatccaccac
     1141 atacgttgct tgcgttttat caacaagaac ttcaaggtga ttacggtcat gctcactcgc
     1201 atttgtcatc gtaaaacttt caggatactg attggtttta tcaagataac agagattcaa
     1261 atgtagcttg atgccagact ttgttttccg aaacttggcc catggaaacc atgctttgtt
     1321 caacggaata gtcgttgaat caatcaattg tagactggtt gtttttgagc ttggctgctg
     1381 agcagaaatt ctggcgacta attgcgtaaa aatttccatc aatacttctt gcttgatttc
     1441 tggcgctcta cgagataacg agctgtaaca cagggaatca atgccaagtt ccttgcagag
     1501 gcgctgatct aaaaaggcgc gatcaatctc gcgatagctt ggcaattctt cataaaccgc
     1561 atgaagtaac actttaagcg tcgtttggaa gtctagtttt ttactgtaga aatcaaagtc
     1621 gctaattaag ctttgagagt tttctgataa accagaaaaa tttattgcag aaaaccattt
     1681 ttgaaatgag gtttttacgt tatacttatc catgcgtgag tcctttttat tggtcttgga
     1741 taagtcatcc gagaatagta taaaggactt ttttgcgttt ggatagcttt gtattaggct
     1801 tttgatgggt taaaaagtct ttgcaacact agtaatttag tatttatgta taaattgaaa
     1861 gatattttac caccacttag tcttcttaaa agtgatccaa cattttgttt gtggcagaat
     1921 ttaactacac actaatgcag ccgaaagtac acaactatgc agcagtttga ctgcgaactg
     1981 gtttccttcc atcataagtt tgaatgactt agtgatggag gtacagaaag gttgttaact
     2041 ttggatgata ttaaaacaat aaaacatttg agaaataatc gtgatcagtc aattgatcag
     2101 ataagaaaag caatgaatat caattggcga acagcgaaaa aatacgccga tagtgatcaa
     2161 ctattcatta cagatcccac tcgaaaaaac aaatccatga tggatgatgg ttggggagaa
     2221 atcatcggta gttggctaga agaagaccta cgtttacgca gaaaacttcg tagaacggcc
     2281 aaagctatcc atgaacaatt gaaacctttg ggtttccctg gctcctatcg aacagtttgt
     2341 gtatacattt ctcaatggaa aaagcagcgt tacgacgaaa cgaattacca agctgtcgat
     2401 cgtcttgatc atccgatcgg agaagcacag gtcgattttg gaacaatgga agttatgcat
     2461 gaagatcaca tgaaagatat acaacttctt atcatgtcat ttccctatag taatgcgacg
     2521 tccgcaagtg ccatgccagc tcaaaaccaa gagtgtttcc tggaagcatt aaaacaacta
     2581 tttaatcaat gcggcggcgt tccaaaaacg atcagaatag ataacttaac tccagcggtg
     2641 aaaaaaacaa aatcaaaatt tgaagaagca caactaaccg atgaattctt acgtttcacc
     2701 attcattatg gttgtgatgt tcaagtctgt aacccacgta gtgggcatga aaaaggacat
     2761 gtcgaaaata aagtgggtta tgtccgatac aatttcttct cgacttcgcc aatcatggac
     2821 tcttttgagt ccctaaataa gcaacttgaa gaacaattaa aagcagatcg aaaaaggacg
     2881 cattattcaa aacatcaatt aatcgaagat ttgtggaaga aagaaaataa agcgttacat
     2941 tctcttccac aagaggatta cccaattttt aaagaagtgg aagctaaact aaatcgttat
     3001 cacgaaatga aattggatca aacggttatt catattccta aagcatatgg ctattctcaa
     3061 ttgactgttg ttttgacttg gaataaattc aaagttctta cgcctcatgg agaaatatta
     3121 atgaacgaat atcgccccta tatgaacaaa aaaagattga tcccatggag tgacatcatg
     3181 aaacaatgga gtaataaatt gaatgtcgtt agttattcga ggtattggaa gtacttgcct
     3241 gcacgccttc aaaattatct agcgattgat aataatcacc tgaaatacag acggataaaa
     3301 caattactaa gtttattagc gacctacgat atccaacaaa ttaatgaaca attttacgaa
     3361 ttagtcgttc aagaagacgc cccctctgac tttgatgtga attggtcaaa ctatgatgca
     3421 ttaacaaaaa caggaggtgt gcaaaaatga ttggacagac gttagaagat tattgtaaaa
     3481 agcttcgatt aagccatatc atcacgaaca taccaagagc ttctttcgaa gctccagaac
     3541 aatttattac cgatttattc cgtttagaac tggagaccag acagcagatc aaattagaac
     3601 ggatggaaaa attagccaaa tttcctgtac caaaatcgct aaagaactat gaatggcacg
     3661 aagatatttt tctaccatct catctagata aggagaccct tgtctctctt gattttctaa
     3721 aaaggcaaga aaacattgtt tgtgttggct ctcctggtac agggaaaaca catctagcga
     3781 tcgcattagg gagaaaagcc tgtagtgaag gtgtttcaac caaatttttc cgagttaaca
     3841 atctcgtaga gcaattagag aatgcattaa aaaaacaaca gctagccagt ttcaagaagc
     3901 gattcgaaac aacagaatta attattcttg atgaaatggg gtacttacca ttgacaaaag
     3961 aaggagctga acttctcttc caactgattt cagattggta tgagcaaaag agcattatta
     4021 ttacctctaa tttagaattc agtcaatgga atcgagtgtt tatggattct cgattaacag
     4081 ctgctctcgt tgatcggcta atccatcacg ctcacattat cagcttcaaa ggcgaaagtt
     4141 tcagattgaa aaattcatta tctaaatcat attgaaggaa aaaactagtt gcagcaaaac
     4201 tctgcacttt cggctgcatt tttttgtaaa aagctattgc acaacacaaa catttgaacg
     4261 acgtaattcc aaatgttgga ttgcttttag ataatctttt atttattcac aattgctaat
     4321 agtccaattt tcatttttgt atagttttaa tctatactga aaaacacttg ttgttttgga
     4381 caactcatca agatactcaa caccaacaat cacttgaatc gctttaccct tttgtttgta
     4441 aataggattc actaattcca caaatttcaa attagtatta attggttgca tcgcgtcttt
     4501 ttcaacataa tgctctagtt ctttttctga ggctgctgga taaagcctga aaaacgtctc
     4561 taaaaactcg gtgatttctt ccgttgtctt tgaatcaatt tttgaatcac tttttacttg
     4621 tcttacttta tgttttgcct tttctggctt accaatcata gtgggtaaac tcgttacaat
     4681 atgattgcct ttttcatctt caaagatcat cagacgatat gcagaagaaa ttgattgtgt
     4741 ctttttccct tctgtaatct tttgatctac cacaaatgaa acgacaaatt cttccgagtg
     4801 tttttcaaca tctagaattt ttactgatac aacctcggaa ctagtgggaa tatccgctcg
     4861 aaccatatct tggctcaaag cgagcccttc ttctgtaagg tactgctcaa gattagtcat
     4921 tctcttttca attacctcct tgttattctt ccatgaaaaa tattctttca caaaatctac
     4981 agtaaaattt tctactccag aggtattcac tattttctct ttcacgacca ctttctcatg
     5041 agttgtatgc tgatcaatgg ccgtgaagtt tttgtagatt ccaaaagcaa ggctacaaga
     5101 caataaaagc caaagggcaa gcaccatttt tcgatgcttg cccacggata ctactcgttc
     5161 tttcttcttt tttggaatct tttccttgtt acttcgctca atttttatct tcattttcca
     5221 ttcctctttt ctattgttta taccgaccag caccaataat gtgctgttgc caatagctat
     5281 cggtaagatt ggtccaaccc accggatctc ctgcatgaaa cattctgttc tctcctgcat
     5341 aaatgcccac atgagtcaca taagtaccgg catcataagt tgaatgaaag aaaatcaaat
     5401 cgcctggttt ggcatctttt aagtcaatat gagtcatagc atcatattga tcctgagcca
     5461 cccgagggag tttcaaacca actttggcat aacaccattg agttaaacca ctacaatcaa
     5521 acccagttcc gggacttgac ccaccaaata cataagccgt tccttcatac ttgaacgcct
     5581 cgtcaaaaat tccttggact gttttatcat caaactgtgt tgtagttagg tactgcttca
     5641 ctaataagca ataaaacata ttgccatagt tataccgcca cccactattt tccttaatcg
     5701 cgatgggatt gggataatcg actttttgac cacccgattt ttcttttgaa aaagattcgg
     5761 ctaaagcaaa actatgcttc tttccgtttt tcgcgacata atccaaatac ccgtcaccat
     5821 agttataagc ctgaatgata ctatcttgat cgcatcctag ttctttggaa cacttaacca
     5881 aagacgaaaa atagagacac acttgtttga tggatgcctc ggtacttaat gaattcggtg
     5941 ataaacctgc tgattcagaa ctttgcatga catcttccat tgtacctcca gattcgactt
     6001 gaataatcgc caaaagaatc gaaacatact ctgttatatc tgattctttg gcatactttt
     6061 ccaccattga acggtgtttc aaaactactt ctgagacact actacctcca ggagaagttc
     6121 cagaactacc acttccctca ccgtcctcac caaacaacaa acccacacac atcaagatgc
     6181 ccacaaaaga gatggtcagg aaggttaacg aaataatact caattttttt aagttcatct
     6241 tttctcacct ggctttggtt ttgggcgagt gttctttttt ctttgtactt gttgattggt
     6301 tcgctttgga aaagtgaatc tctgtttcac ttgttgaaag gaattgttct tgcttagtgg
     6361 ctgagtgctt ccgtttggaa tgacttcttg actagaaagt ttccgtttga tttcaggatt
     6421 cgaatgtact tgtacccttg gttttaaaga cctattttct ggtagttcat ttttctgtgg
     6481 ttttatctcc ttttttatcg gaacattttc ccttcctttc tcatgacgat tccatgcttc
     6541 gttcaatact ttgcgttttt catccatttt tgcgtctctt cgttgtcgtt gtttttctcg
     6601 caactcccct cgatttgctt tttcttcgaa aggccctcgc ttaaagtcct ctggtacttt
     6661 tttcgtcttt tccatgcctt tatgaaggct gtatttcaag ttagttggtg catcggttac
     6721 ttgatttttt gcttgtttcg ctttgtcctt cacgatttct tttgtatcga gtacttttcc
     6781 aacttttcta ccaactaaat ttattcgtga ttctttcttc gtgcccactg gttgttcttg
     6841 ttttttcaga tcagaattta gctcgttaat gcttctcgcg gaatggttct ttctattgga
     6901 cactctattg atttttgaac tacctttccc ttttgtagaa ctggtagcta gtttcccacc
     6961 aactgctgca ccgccaccaa aagcaaaagt tcgacccaca tttcgattaa gctgtcgcaa
     7021 ttttcgattc atcaacattt gcggtttccg catgactcgc cttcccattg actgactatc
     7081 attactttga aggttaaaca tgctcataat gtcacctaat ttgaaataga taccggcaaa
     7141 ggtcacaatt tgtagaaaag ctaccataaa gaagggatag gtggccgaaa tattgaaaaa
     7201 catcgtggag atactgaatg cagtcgtaat gactaaggta actcccgctc gcatcataat
     7261 cgtattgaac aaacgaataa tcgccctttt gcccaaactc tcatacgtcg gcaacatcga
     7321 caataagaaa ctaatgggca gaaacatcgc aaagataatg aaaaggattt gtgagaacaa
     7381 cataatccct gtcagaagaa acacaaaaaa ggaaatccca atattaaaca acactaaaaa
     7441 gaccacggtt cctaaacggt tcatggtctt ggtaatactg agattcgcat tgtcattatc
     7501 ttcaatctct gctttgactg cttcttcccg atccttaccc ttattttcat ccggactcac
     7561 ggataaaatc ttattaaccc gaccctcgcc aatttcttct atattggaat catcgaattg
     7621 taatagtaac cagggttgtt gaacttgaat cgaaaataaa ctgtctcgaa tcaaatccac
     7681 actatctttt ccctggcttt ctgaattagg tacaacaatc ttggttccaa ggctaagagc
     7741 cgcttcacta acgtctgagc taaagtcatt gatttttgta atataggtgg gcgcatacgc
     7801 aatgaaagaa cccgagagta gaaaaatcat cacaaaatta atgacggttc ggactgcttt
     7861 ggtagtttct cgttttaata atccggtata cgccacataa actcctagag ctaaaatcat
     7921 caataatagg aacccaaagt agaatcccga agtctgtaat ccattttcag tgataccggc
     7981 taaagtttgg atattctttc caatactttt agccgtatcc gaaatgaaat ccaacttgta
     8041 agcttcttga accacatagc ccgtggcgtt tgataaatac agacttactg tccaaataaa
     8101 attggtaatg gcataaagac catacatcac gcttttccct aagccatccc cccaattcca
     8161 aggtaaccaa tcccaagaac tatccacaaa gaaatccagt tgataattgt tcagagaata
     8221 tttggaataa aggtttccgg cttcaactgt atcatcaacc agacctgtcg cctcagctac
     8281 cgtaccgact aaactcaata gaactgtcag agtgacgatg ctaataaaaa cgattcccac
     8341 aatccgaaaa agtttctttt tcatcccctc actccattct ctcttgaacc ggcggacgag
     8401 tgtcaaaagc atggaagagt tcttcaaaga ctggatgaac ttgaaccaca cctactcgcc
     8461 catacaagtc ttgcatcaag cattgaccgt tt
//
LOCUS       DAIGSZ010000094         8424 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.097, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000094 DAIGSZ010000000
VERSION     DAIGSZ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.097"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..505)
                     /locus_tag="NOB31_002601"
     CDS             complement(<1..505)
                     /locus_tag="NOB31_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974772.1"
                     /translation="MISIIWFLFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKD
                     NSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLS
                     RIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLL
                     NICTILIS"
     gene            471..2108
                     /locus_tag="NOB31_002602"
     CDS             471..2108
                     /locus_tag="NOB31_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974773.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2253..2993)
                     /gene="truA"
                     /locus_tag="NOB31_002603"
     CDS             complement(2253..2993)
                     /gene="truA"
                     /locus_tag="NOB31_002603"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCI0974774.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3184..3819)
                     /locus_tag="NOB31_002604"
     CDS             complement(3184..3819)
                     /locus_tag="NOB31_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HCI0974775.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3966..5207)
                     /gene="sstT"
                     /locus_tag="NOB31_002605"
     CDS             complement(3966..5207)
                     /gene="sstT"
                     /locus_tag="NOB31_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HCI0974776.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5405..6401
                     /locus_tag="NOB31_002606"
                     /pseudo
     CDS             5405..6401
                     /locus_tag="NOB31_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            6417..>8424
                     /locus_tag="NOB31_002607"
     CDS             6417..>8424
                     /locus_tag="NOB31_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCI0974777.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
BASE COUNT         2785 a         1547 c         1293 g         2799 t
ORIGIN      
        1 aactaatcag aatcgtacaa atatttaata accaaatata tagaacataa cttaatatta
       61 agttatttga aattccataa aaaacgactg caggaattat tgtaagaaaa ggataaaaat
      121 agttcagtcc atctccataa ttgttaaatg ttgtatagtt gattggccct tcaaaaatag
      181 aagataaccc tttgattcgt gaaagatgaa aagataaatc acctgttgta taaatttctt
      241 gagcatttct cataaaattt actgaatata aagtactaag taagataaga actactaaaa
      301 gaaatgcttt tttacttatt ttcatagatt tgttgttctc cttttttaat tctattttca
      361 gtatactaga attgtctttt tttaataagt tttgcgttaa atttttcata gcactagtat
      421 gatatactag aaaagaatca atttttatta cttttaaata ggagaaaaaa atgaaaaaaa
      481 acaaaaacca aataatagat atcattttta tgttatttct aagttttgct tacgtcatcc
      541 ctctattcat gtctatggga atctatcata gtgtcaatca ggatacttac tttcatttat
      601 ctcgaatcat aggactagat aatgtatgga gttctccagt aaacttcaat aacttcgatc
      661 atcatggaac aatgatgaat attttttatc catggcttac tctttatcca gcttttttat
      721 tttataaaat gatgggaaat cttgttttaa gttataatat ctactatttt tttatcactt
      781 ttttaacaat ggtcgtttct tatttttcta tgaaacaaat aaaaaacaat cgttatattt
      841 cgctgttatt ttcgattatt tatacatttt ccgcctatcg tgccattgac atattccatc
      901 gtgcttcatt gggagaagct gtcgctttaa catttttgcc tttgatacta atggggtgtt
      961 acgaaattta tattagagat taccaaaaat ggtactggtt gtctattggc atgacgctag
     1021 tagtgtatac tcatttactt tctgtcgcta tggtttctgt atttattgga ggaacgttgt
     1081 ttctttcttt ttatttttgg gaccaaaaaa tcgctagact cttaagtctt ttaaaagcta
     1141 ccgtcctcac ctttttttta agtgcgggat tcttaattcc ttttattcaa caatctagag
     1201 cacaagaatt gaaagtccca ctgggaaaag aattaagtgg tatggctcct agtgatatgc
     1261 tgacacacat tttaaataat aactataaca actatactat tggattattc ttatttctcg
     1321 gattgattgg tgcttttatt tttataaaaa aattaactgc tgatgattta tttattttct
     1381 ttcttggtgt atttgttctt ttttgttcaa ccaatttatt tccttggcaa ctttttaacc
     1441 atacaccagt taagagtcta caatttgtct ggcggttaaa tggtttttct tctttattta
     1501 tagcctatac gatgagtata gtgatctatt atattttttc tactaaaaat aattcatgga
     1561 aaataatggt ctttacgttt cttgcactaa tattgcatct ctcaggagta agcaattcta
     1621 tccatgctaa caaagattca ttaacactta tagcacctga agacgctgtt gctatagctg
     1681 aaaattacaa tcatactgat tatgcaaaca aagagtcaat ctatcatcct gatatgatta
     1741 ataatgatca atatttacta ggtaaccagg aaataaatcc aacaactcat tttatgagta
     1801 acaaacttac aattgaatta gataattcga ataataaaaa tactgtcttg acgacaccta
     1861 tttatcgtta taaagggcaa gtggcttcta ttaatggcaa actagtacaa acaaaattat
     1921 ctaagtttgg cacaactgaa ttaactattc ctccaggtat aaataaagtc gttattactt
     1981 atcagtacac aaaactagca attgcttcaa gatatttatc tatcgttact ttgattttat
     2041 ttttacttta tcgatttact ttttctaaac aaaaacaacc gagaagagaa gtacaacatt
     2101 ctcactagat ttttatttaa gaaagacttt ttagctgtac acataaacag gctaaaaagt
     2161 ctttttttat atttctttaa tttgcttcat acattattta acatcgatat ttatactgtg
     2221 aaacatgcgt ttcatccatt atcaaagtat ttttatcgat aataaacttc atccaaaaac
     2281 agaccttgtg cagggacggt ttctcctgca tgttgccgca ctttgctttc aaatatttca
     2341 tcgattgttt ctatcggcat ggcacctgtg ccgatttcta gtaatgtccc catgataatc
     2401 cgcaccattt tatataagaa tccgtctccg acaaaagtaa aatgaagcat ttctcccttt
     2461 cgttcgatag ataattcatc aatcgtacgc actgtggatt tttttgattt tttcaatgca
     2521 gaaaaaccaa tgaaatcatg tgtacccact aatttttcgc aagctgcatt cagcttgtcc
     2581 atatccaact cttgagggaa ataaaagctg tggtttcgct caaatgctga aggaatcacg
     2641 ttgttccaaa cataatagct gtattttttg cccaccgcat tatatcttga atggaagcgc
     2701 tcaggcattt cttcgattct tttgatgaca atatcccgcg gaaggtaacg attcataaag
     2761 tcgatcattt ctgccagtcc aatttctgtg tttgttttaa aatttgctac ttgtcctcgc
     2821 gcatgggtgc cagcatctgt tcttcctgat ccaataattt ctatctcttc atttgtcatc
     2881 tgatgcaata ctttttcgat ttttccttga atggttttat cgtcatctcc aagtctttgc
     2941 catcctgaat atctttttcc gtcatattcg attgtcaact tgatgtttct catattttag
     3001 tggctcctct gtcttccatt tggtcttctc tctacctttt taagattgta gcacaaaata
     3061 tagctccttt cttctctaaa acagaagcta tacaagaaaa ctgtggaaat atatatttca
     3121 gaaaaacaaa aaacagccac cggatgaagt atccgctgac tgttcaattt gacggctcaa
     3181 gttttactgt ttgagatgca agatactcaa ccaggcaatg ggcacataat taaagaaaaa
     3241 actgattctt tggcaaaaac ctattttatt cagtaatggc caagaattta tagaaggaat
     3301 tcttgccagt ccataaatcg ccgcaaaaag caaactgatc acagacagtc caaggtataa
     3361 gtggcttacg tccatttgcc cattttttcg atagatcaag aaaagaagaa ctggaaacaa
     3421 taaaaaacca ctgtaaccta aacctgatcc gatattatgg acccatgtcg agacattcca
     3481 cgaagattca tgggtattga tactgaacaa acctgtaaag atacaatcac ctataccata
     3541 gaacgcgatg gctgctgtaa ctagggtagc taacacacga gatgtactta caaatgcagc
     3601 atacaatgca ggcaatgaca ggatgaaaaa gatccctgaa accacagacc aaataagaaa
     3661 cgcttttctt acaggactgg aaacctctcc aaatacactg atcacgctct tcatttgatc
     3721 taattcagga taatacaatc ctaatacgta cggagtcaaa aaatcactca gcacgcctaa
     3781 taataaaaag aaaaaaccaa atttacgtaa aaaatccatg atacgcctcc aataacaatt
     3841 acctatgctt ttaattgtta ttataagcga ctttatcttg atttaacaga aacctctatt
     3901 tacacgaaca tctatataac tcattaaaaa ctcgaatcat tttaaaaata ctaaatatct
     3961 aacgttcaac gttcacttaa tccatctaaa caatctttca atttgatttt ttccccactt
     4021 cttttacgcg cgcctagctc tcctattgca gtaaacaaca gatcacttga cgaatttaag
     4081 gcagtttcca ttgaatcctg gataacaccg ataataaatc caataccgac gatttgcatc
     4141 gcgacatcat tagagatacc aaacaaacta catgctaatg gaatcaataa cagtgaaccg
     4201 cccgcaacac ctgaagctcc acaagcagct aaagcagaca aaatacataa aaggactttc
     4261 aaaacaaaag gtgcttcaat ccctaaagaa tgtacagcag tcaacgtcat caaggaaatg
     4321 gtaatcgcgg caccgcccat attgatcgta gcacctaacg ggatcgatat ggaataagac
     4381 tcttttgtca atttcaatct ttcagccaac atcatgttta tcgggatatt tgcggcagaa
     4441 cttcgggtaa agaaagcggg aagtgcgctt tctttcaaac aaaagaaaat caatggatag
     4501 ggattttctt taataaacaa aaacgtgagg aatgggtaca caactaatgc gacaaacagc
     4561 atcgtaccga tcaaaacaag taaaagctgc agatactctg ccaatccagc tattccagtc
     4621 gtagcaattg attgataaac caatcctaaa atccctatcg gagcaaatgc aataatcact
     4681 tgtacgactt gtgacaacgc tatagatatc tgatccacca actcttttgt cgattctgaa
     4741 cgtgctcgaa aagctagtcc caacaataca gcccagaata agacgccaag gtaattcgca
     4801 tcaataagag attgaacagg attttgtgtg acattcgtca acatagtaga taaaacactt
     4861 tccaaacttt gcggtgcttt ttcagatact gtttcttgta aagtaatagg aacagtaaaa
     4921 attgaactta caataactgc tacaagtgca gaaagcaatg ttcccactaa atataagatc
     4981 aaaataggct tcacgaatgt cttattccca attttatgct tggcaattga cgccatcgtc
     5041 aagaaaaaaa ccagaatagg tgcgattgcc ttcaagcaac tgacaaacaa cgttcccaat
     5101 attgaaataa atgtccatgt ggggaaaaag ataccaaaca atattccgac taaaatacca
     5161 acaacaatac gttgaactaa cgacatatcc aaaaacttct ctaacaaatg accacccttt
     5221 cacaatttta acaatcattg tatcatttta tgcaaagaaa ctaaaggtat aattttctaa
     5281 aaattctaac aatacaaaca accatttctt gctaattttg tactttttct gtctacacgt
     5341 tgttttttga gatattctaa gttaggatgt tattaatggg caacttatca ggaaacgttt
     5401 tcttatgttt ttgtccaatt tttttgtgag gtgtttattc ttgaaaaaaa taaagaagga
     5461 gagttatggc ttcctgacaa tctttgtcgc ttgtataatg atggttttac agcgtatatt
     5521 gatttcagca gtcactattc ctacatatgc aacaaaccct ggtcgattct acatctatac
     5581 atttttacaa acttccgttg ttattggtgc aaatttgatc ccactttaca tgggttacca
     5641 atatcaaaaa atcgcccgtt taaaagtttt acattattta agtcgttttg cctttatatt
     5701 cctaatagcc acactagttt gcaatatctt ttttttacgt acaagctggc agcttgaata
     5761 ttcgtgatta ttggcttatc ctaacaccta tcagtcagaa ttactttact tatgctgttt
     5821 cttgtacttt gcttttttgt agtattcctt atacagttgg atttttaaat aaattatcga
     5881 aaacaacaat taaatatcta ctattatttt taacaattgg attagttggc tgctctactc
     5941 tatttaataa agacccgttt gcattacaga atggacagag tattttatgg attttttatt
     6001 tatttttaat gggttatggt ttgaaagaat ggaactggaa agaaaaggtc cgctataagc
     6061 ttcctcaagt atttatcagc ttgattgttt tattcggttt gattattttg atgacacaaa
     6121 tttcactcat catcagagga aatacagata cagcgctgag gttttctaaa ccatattctc
     6181 tcttcgcaat gtattatact ttctcttcgt ttttattttt agaaatgcta tctgataaat
     6241 taggtataaa aggaagagga aattttcttg ctgtattttt gattgtcact caagttatat
     6301 gtaatttccc tttagtttct tatcgcgtat ctacatttat gaaacgtgaa tttccaaact
     6361 cagggaaggc atggctgata aatatcgggc agttttttat ttgctattta ttagcagtgt
     6421 ccctcctagt tatcttttta ttttatatac aaaaaatccg tttcattcat cgtttcatcg
     6481 aatacttcgc ttttgattcg attgaacaat taactcagcg ttggaaaaaa agaattcatt
     6541 ggctttttgt tcataaaagt tattttttag ttgcagcatt tttttactgc tttaccttcg
     6601 tgcagatttt cgttttagaa ccaaaagaag gttggaaaga aactatccag gttgccttaa
     6661 aaatatttac tcagcgacaa gcacccatga tcctgacaat catcattatt atgggatttt
     6721 tcttcttact attgttgatt tccaatcgtt tttggtacgc cttgactgct accttgatca
     6781 ttaacttact gctcactatt tcgacagtaa tcaaaatgga aatgcgggaa gagcctgtct
     6841 ttccttcaga tttaaaaata ctgaccggat tgtcagaact attatcgatg gttagcccag
     6901 tcttattaat cgtgggcgga ttgatccttc tcctattatt gattactagt attattgtac
     6961 aacgtagact acaaaaacag tattccttga agattcattg gaaacgtcga tttatcagta
     7021 tcgctgtatt attaggatgt ttttcgggtg tctttttcat taatcacaaa aattcgcctt
     7081 ctttcttgct gtttaattta tttaaagtaa acaagacttt ctttaaccag caaggcgccg
     7141 taaaagataa cggaccagtc attcaattcc taaacaatat cgacattaaa atcatggaag
     7201 aacctgctgg ctattcgaaa gaaaaaatta atggaataat gaaaaagtac aacacaaagg
     7261 cagatgaaat caaccaaaca agaagtgact ggttaaacaa tcagacgatc gttctcaatt
     7321 taagtgaaag cttcagtgat cctgcacgtg tccctaatct gacagtacct acagacccta
     7381 ttccttacat caaaagcatt ataacagaag gaacaggagg attgatgtta tccgtcggtt
     7441 atggtggcgg aacagctaac atggaatggg aaggactgac aggcttgagt atcagtaacc
     7501 tgtctgcttc gttagttaca ccttataccc agctagtgga gcgtcagaaa ataagtccaa
     7561 atattaccga tctattcgat gaaaaaatag ccatccatcc ttttacagct gctctttatc
     7621 gcagaaaaca agtgtttgat aaatttggtt ttgacaggtt ctattattta gacagtccgg
     7681 ataaattaac ttatacggat aaaatagaac aaagcccacg catatcggat gattcagcat
     7741 acaaagaaac cttgaaagct ttacaaagca atacagaaac gtcacaattc atccaattat
     7801 ccactatgca aaaccatatg ccttatgatg attactatag tgaattgaac tacactgctg
     7861 aaggaactgc tgtcattcct aatagaagaa aagaattaca aacttatatg caaggccttc
     7921 actataccga tacagcagta aaaaaattca tccaagaaat cgacaaaatc gataaaccga
     7981 ttacctttgt tttttatggt gaccatttac ccgcaatcta tagtgggaat gattcgaaaa
     8041 aatatggatt agaacagcac cagacagatt atttcattta taacaacaag tatagtcgtg
     8101 aacaagcagc tacgttaaat aaagaagttg ttgctcctaa taactttggt gctatggctc
     8161 ttgagcatgc gaatatcaaa gtaactcctt actatgcgtt gttgacagaa gtatctaatc
     8221 atctacctgc attaacaatt gatcctacag aaagcttgtc taatcgtttt aatggaaaac
     8281 aggtctttgt tacagaggat agtcaaatta tccaagaaaa aaatttaact gagaaacaaa
     8341 aagaaattct agaagattat cgtctgatac aatatgatct tgttgcaggt aaccagtaca
     8401 gtgcaacatg ggcgacacaa aaaa
//
LOCUS       DAIGSZ010000095         8252 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.098, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000095 DAIGSZ010000000
VERSION     DAIGSZ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.098"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            64..3291
                     /gene="fss3"
                     /locus_tag="NOB31_002608"
     CDS             64..3291
                     /gene="fss3"
                     /locus_tag="NOB31_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HCI0974778.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            3403..3717
                     /locus_tag="NOB31_002609"
     CDS             3403..3717
                     /locus_tag="NOB31_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI0974779.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            3730..4104
                     /locus_tag="NOB31_002610"
     CDS             3730..4104
                     /locus_tag="NOB31_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCI0974780.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            4105..4458
                     /locus_tag="NOB31_002611"
     CDS             4105..4458
                     /locus_tag="NOB31_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HCI0974781.1"
                     /translation="MKNMEINVEHILDCLDQFGKGELTEEQLTNALTYDEKMFLIMHQ
                     GLLEVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFL
                     KQLVETKQLPVVVND"
     gene            4527..5543
                     /locus_tag="NOB31_002612"
     CDS             4527..5543
                     /locus_tag="NOB31_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HCI0974782.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            6137..8011
                     /gene="ltrA"
                     /locus_tag="NOB31_002613"
     CDS             6137..8011
                     /gene="ltrA"
                     /locus_tag="NOB31_002613"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCI0974783.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
BASE COUNT         2862 a         1409 c         1758 g         2223 t
ORIGIN      
        1 taaacaaaga tgttcaagcg agcatcttat ttttttgtgc ctaatttgaa aggagaacat
       61 ttcatgtata aaaaacaaaa aaagaaatta tgtgtattaa ctattttgag tttggctgtt
      121 caatcaattg taggagcaat tgctcctacg attgcttttg ctgatgaaat tacccatcca
      181 caaacggtaa ccgtagaact agatttagca catcaatatg ctgttgaagg aacttttagt
      241 gatggtcgtc caatgtcaga agtcactgtt ccgcattatg cagtgtacaa cggcgttaaa
      301 caagatattt tctgtgttga accaggagtc ccgatttaca atgagttcac tcctggatat
      361 gagaagaacc cgttaccaga tatgtccgat aaagccaaat tagtttccgt tttatggaaa
      421 aaagtaggta cagatgcaga tactcatatt gtggcacaga agatgatctg gcaagaagtt
      481 aatgggtata cccttcactc aataaaacga tcagatggta gtgccgtaaa tatcgcagcc
      541 attgaggcaa aaatcaatca agccattgcc gattatcaga agaaaccaag cttccataat
      601 agtacggcta aaacagtatt agggcaatcg actactgtga cggatacgaa taatctgaat
      661 ttgtcagagt tcgatgaggt tgtggaaaat accgcaaaca ttgattatcg tgtgaatggc
      721 aatcagttga taatcagccc aaatgccaat tcaaaagaaa gtggtgtgtt gacgcttaag
      781 aaatctgctg gtaccggaac acctgtcgcc tataaaaagg ctggccaaca gactttaatg
      841 gccggggcga tcgataagcc gaacacttat acggtcaaaa ttgatgtgga aatggagggt
      901 tctttgaaga ttaaaaaagt tgataaagaa tcgggtgata ttataccagg aacggttttc
      961 catttagact ttggaaaaac tttacccgca aaagacgtga ccaccgataa agaaggcatt
     1021 gcgaccttag atgagattcc tcatggtaca aaggtaacca ttactgaaaa atcggtgccg
     1081 gcgccttata cgattgatac cacacccatg actgccacaa ttaaagcagg tgaaaccatt
     1141 tcagtgactt caaaaaatac gcgagaaaaa ggtcaaatta ttctggataa aaccggaatt
     1201 gaaacaggga gtgatctttg gaacgataat tactctttag cgggcaatac gtttgccatt
     1261 cgcaaggata gcccaactgg tgaaatcgtc caagaaatga ccacggatga aaaaggtcat
     1321 gcagaaacac caaaagagat tgccaatgcg ttggaattgg gaacctacta tgtgactgaa
     1381 accaaggcta gtcatggctt tgtgaatact ttcaaaccag taaaagtcga attgaattat
     1441 gtcaatcaaa cagtggctct tgttaccagt aacgtaaaag ggcaaaacca agaaattact
     1501 ggtgaaacca ctttgacaaa agaagacaaa gataccggtc atgaaactca agggaaagct
     1561 gagtttaaaa gagctgaata caccttgttt actgttaagg atggaaaagc ggtcaaatgg
     1621 accgagaact ttaaaccaga attgttgaag ggaacgaaag cttctgatga aaccgtaact
     1681 ttgactttag atgaaaagaa tcaagttgcc gttaaacact tagcgattaa tgagtattac
     1741 tggcaagaaa ccaaagcgcc tgaaggatat accttggatg aaacaaagta tcctgtatcc
     1801 atcaaaaagg tggatgatag cgaaaaaaat gctgtgatta ctcgagatgt tgcggcaaaa
     1861 gaacaagtga ttcgctttgg ctttgatttc tttaaatttg ctggatcaac tactggcact
     1921 gccgaaactg gcttcaatga tctaaccttt aaagtgtcgc cattggaagg aaccaatgaa
     1981 atcaccggtg ccgaagatga agcgaccaca gcttataacg agcaattagg gtttgatggt
     2041 tatggcaagt ttgaaaatct tccttatggg gattatttac ttgaagaagt agaagcccca
     2101 gaaggttttc aaaagattac gccattagaa atccgttcta cttttaaaga aaataaagag
     2161 gattatacca agagtgatta tatctttact attaccgaaa aagggcaaaa gcaaccgatt
     2221 aaaacggtaa cggtccctta tgggaatcta accaatgaga atttctcagt cagtttgaac
     2281 cgtttgatgc tttatgattt gcctgaggaa gaagatagct taacttctct tgcgacttgg
     2341 aaagaaggag ataaagaatt gactactctt gattctaccg agctagtcga taaattgagc
     2401 tataatctac atgaaatcaa agaagactgg tatatcgtag ctcaagccat cgatgtagat
     2461 gctacaaaag ctgcccaaga aaaagataaa aaagccaaac cggtggcgat tgcggaaaca
     2521 accgcaactt tagcgaataa agagaaaaca ggaacttggg agattctgca taaattaact
     2581 gtcgaacaag ttttagacaa gaccattgtc ttattcaact atgtgtatga aagcaaagaa
     2641 gcctatgaag ctggtgatga gccggtagcg aaggatgcta gcttgaacaa tcaagcgcaa
     2701 actgttaatt gtatggtgga acgtcatgtt tccatccaaa ccaaagcgca cttagaagaa
     2761 ggttctcaga cctttactca tggtgacgtg gtagatatgt ttgatgatgt atccattacc
     2821 catgatgtac tagatggctc aaaagaagct tttgaaacaa ttctgtacgc tttatttcca
     2881 gatggtacaa gtaaagaaat ttggaaatct ggcaagattg attacgaagt gaatgacaaa
     2941 gaatttacca aaaccgtact tgcggaaaaa gtggatacaa gtaaatatcc agaaggtaca
     3001 agttttacct tcaaagaaat taactatgac aaagatggga atatcaatgg aaaacacaat
     3061 gaagatttga aagaaaaatc tcaaacttta acgcccaaaa aagttccgac aacaccaagt
     3121 acaccagaac aatctgaaat gccaactgtt ccaagtggct ctcaagaatc tagtcctaca
     3181 gtgaaggcat tccctcaaac cggggagaaa acttccaatg tgctactgtt cattggcttt
     3241 agcttgatct ttgcgacggc tggctattat ttttggaatc gtcggaacta aggtgataag
     3301 atgaaacatg taaatagtag aaaacaatac gcgcgaccgc ctcctaaaaa agtggtcgcg
     3361 ctatttttgt attcaaaact aacaatgaaa agaggaaaaa atatggaatt gaaatttgtt
     3421 gtaccagata tggtcgagac gttcggaaaa ctaacatacg gtggtgaagg tgaagttcta
     3481 tcggaagggt atggtcgaaa tactacaatt gttggtcgaa gttaccatct gttttcaaat
     3541 aaacaacggg ccgatgatat tgaagtggtg gtagctgcgg aagccggcga aaaggatttt
     3601 gaccaagatc aaccactaaa agctgtaaat ccccacttaa ttgccaaagg ctatgaaatt
     3661 gagaatcgtg ggtttaccga ttacgtgttg tatgttgatg atttagtgaa agcataggag
     3721 gaaaagaaga tgagattaac agaaggtatt gtcgtagatt caggattaac ctttggcaag
     3781 ttgcgttttt ccgcattacg tcgagaagta cgcaagcaaa atgaggacgg aacggttagt
     3841 aacgaggtaa aagaacggac ctataatttg aaatcctccg cgcaaggtcg aatgatccaa
     3901 gtcagtattc cagcaaatgt acccttacgc gagtttgctt atgatgcaga ggtagagctg
     3961 gtcaatccaa tcgtggatac ggtcgccaat tatgtttttc gggaaggaac caccgttaat
     4021 tggtttatca aggcagatga tttagtcttg aaacgacaac tgaatcaagg aaaacctacg
     4081 aaccaaaatg aaggaaagaa ataggtgaag aatatggaaa ttaatgttga acatatttta
     4141 gattgtctcg atcaatttgg caaaggtgag ctaacggagg aacaactcac taacgcatta
     4201 acctatgatg aaaaaatgtt tctgattatg catcaagggt tactggaagt aggtaacgat
     4261 gccaaagaag actttgatgt actggattgg ttaggggaag aagagtcttt ctttatggtt
     4321 gtcgaggtaa atgaaagttt atgtcggcag gcagaatctg ttttggaaga aatcgatgtg
     4381 gagatgccgg atgccatcga aagattttta aaacaattag tggaaacgaa acaacttccc
     4441 gtagtagtaa atgactagca taactttttg aaattgccca atgaaatcct attgggcttt
     4501 ttcgactgga ggtggaaacc atcaaaatgt acaaaggaca tcgcatacgc gcaggagatc
     4561 aacacttgat ttatcacttt gttcttggct ggctaatctt tttgttcatt ggttggatga
     4621 gcgtctttta tttacaagaa cttagacaat ttgatatttc taaggtatca ttttccacta
     4681 gtgaaattgg ctggtctatg aaggatgtaa tctgcttgct aggaagtctc gctctttcag
     4741 gaagcatgat gttactttat atacactttt ttcaggatca ttggcgaagt ctttggcatc
     4801 gacaaaagtt agctcggatg attctagaaa accattggta tgaagtaaag cagactcaag
     4861 gtgaaggttt tttcaaagat ttgaatagta gttggaccaa agagagtatc agttacttcc
     4921 ccaaaattta ttatcgaatg aaagatggct tactttctat tcgcgttcaa atttcactgg
     4981 gaaaatatca ggatcagcta ttgaagttgg aaaataagtt agaaagcgga ctgtattgtg
     5041 agttagtaga aaaagaactc aaagactcct atgtggaata caccttgtta tacgatatga
     5101 ttgccaatcg aattgggata gaagaaatag tggcagaaaa tggggcgttg cgattgatga
     5161 aaaatcaagt atgggcgtat gattccttgc cgcatatgtt aattgctggc ggcacaggtg
     5221 gtgggaagac ctatttctta ctcaccatta ttcaagcact attgaagtca gatgcagaat
     5281 tgtttatcct cgatcccaaa aatgcggacc tcgccgattt aggtacgata atgcctcacg
     5341 tatactccca aaaagaagaa atttctgaat gtgtggaaga tttttacgaa cgcatgatag
     5401 ctcgtagtag gtcaatgaaa gaaatgccca actacaaaac aggagagaat tatgcgtatc
     5461 tcggacttcc gcccaacttt ttaatctttg atgaatacgt ggcttatatg ggtgcgaatc
     5521 gttttcctac aagcatcgaa tagatgtgaa atggaagcct attgagatta tcaatagtga
     5581 caactaatgt tttgagagat ggaatgaaag ccttcaagtt gagctgaaac atccccgcta
     5641 atactcctac atgctctaat caatgaagta gattggtttt ggtatgaagc taggtgaagt
     5701 cgtctgaaat ctgcctaagt gcttgagcat aaggctgact atagggcggg cggctgaaaa
     5761 agataactat ggtaagaatg tctgaaaatg actgacgaat ctgcgaatgt acgggtctaa
     5821 aaggctgatc ttattgaaag ataggaacat acggacgtat ggtgagatac cgacaagtaa
     5881 ggttccatga tatgaaaatc gggatagcta acgaagaagc tataatttca caggctcata
     5941 gtagatacct aaggttatac atgatagcta aaaacattgg aacgatgtaa gcagaaaact
     6001 atcaattaaa tgactacttc tagataggtg catataagta ataacgaaat tgctttgttt
     6061 ctgtgaaagt aagggcacag taccgatgaa gcgtctaaca aatgtggagg gatagcccta
     6121 agtctattta ataacaatga atgttgaaac agatgaagtt caaggatctg gtaagaacgt
     6181 gggaaaatcc gttatggagg tgccacgctt gaacacaaaa atacgttact gggaatatta
     6241 tgatctacaa gaaacattcg atcagctatt tactcaaagt agaaacggga aaaagtttta
     6301 tcaattatat gagttaatca tttctgaaaa taatattctt ttagcatacc gtactatcaa
     6361 ggcaaacaag gggtcttcga caccaggaac ggattccttc acaattgata actataagga
     6421 aatgaaccaa gcagagttta tccatcttat tctcagtcat ttagaaaatt acaaaccaaa
     6481 atccataaag cgagtaatga tacctaaacc caatggtgag aaacgcccat taggaattcc
     6541 atgcatgatt gatcgaatga tccaacagat gttcaagcag atactggagc caatatgtga
     6601 agctaagttt tatgaacata gctacggttt cagaccattg agaagtgcaa agcatgctct
     6661 aggtcgcatt atgtatctca taaacatcag taaaatgcac tatgcagtag acattgatat
     6721 caaaggtttc tttgataatg taaaccaccg tttactgata aaacaattat ggaatatagg
     6781 aatttgtgac aaacaagtct tagctattct ttcaaaatct ctgaaatcac ccattcaagg
     6841 agaaggtatc ccgagcaaag gaacgatcca aggaggtatc atttctccac tattatctaa
     6901 tgttgttcta aacgacttag accattgggt ctcaaagcag tggcatacct ttgaaacaaa
     6961 gtatccctat actaaaggtt acaataaatt tcgtgctcta agagatacaa atctaaagca
     7021 aggctatatt gtcaggtacg cagatgactt taaaatcatg actaatgatt atccgacagc
     7081 attaaaatgg ttccacgctg tcaagcttta cctaaaagac agacttaaat tagatatttc
     7141 caatgagaag tctaaaatcg tcaatttgcg taaatgtaag tcggaatttt taggattcgc
     7201 tatttgcgtg aaacaaaaag ggaaaaaatg ggtttgtaat tcacgtattt ctaacaaaaa
     7261 aaaggatcag attaaagaag agattaaaca aagaatcaaa gatattcaaa agagtcctac
     7321 agcacaaaat gctctcctgt ttaatgctct cgtgctcggt gttcataatt atttcaggta
     7381 tgccactcat attaatttag atttgaatag gatgaactac gttctttcat tcactactta
     7441 caaccgatta tcaaattgta gtacaagatg ttaccccaac aaagcttccc caacttacaa
     7501 aaagttttac tcaacaacga tgaaaacgta taaagtagct ggagtctatt tgtaccctct
     7561 ttgcgacgta tctacaaaaa caatttacgg atttaatacg gaggatacac cgtttactcc
     7621 gtttggtcgt caaagattgg agcacaaaag cctacagtct cttgtgttcc aagaattaag
     7681 aaaattgatg gaatcgaaaa taccgaatag aacggttgag tatttagata gtagaatatc
     7741 tcgttactca atgaaatcag gcaagtgtga gattacaaaa caatttttgc cagcaaaagc
     7801 cgttcactgt catcactatt tgccaaaaag tcttggtgga gacgacaaat tcgataactt
     7861 gagaattatt cataaggata tccatcttct gatccataca acaaataaaa tgataatcga
     7921 tcactacgtg catgaactga aactggtgcc agagcaaata gcaaaaatca acctttatcg
     7981 aaagatgtgt aatctgcaaa acattcaata gaaaataaat agatggaacg ccgtatgagg
     8041 tgaaagtctc acgtacggtg tggagcgggg gaaaagatgg agattatatc aaattcttac
     8101 ctatcgctat agatgttaac gacaaaagaa agtgcggtga ttttgaataa gcttaaacaa
     8161 atcgtgatgt taggccgtca atctggtttc tttctgattc tagcttgtca aaggccggat
     8221 gcgaaatatc taggagatgg gattcgcgat ca
//
LOCUS       DAIGSZ010000096         8073 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.099, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000096 DAIGSZ010000000
VERSION     DAIGSZ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.099"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            709..1602
                     /locus_tag="NOB31_002614"
     CDS             709..1602
                     /locus_tag="NOB31_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0974784.1"
                     /translation="MGKISLGIDIGGTFIKYALIDKQHRIKEKWKVETVKYNTADEFY
                     DYICSNIRNVDEIDKIGVSAPGLIDEDSNVKSYAAPNVAIMYGTNINNEINKRTNKKV
                     SAINDAKAAGLCEFKIGNAKGYKSSAFLIIGTGTGGCICDENGVVYGKDSFAGEFHNM
                     PFVNAEIGGLDKMGDYASITGLVNLYNKKANREEQVQYGNEVCKKYLNGNESAVSSVD
                     EWIGNIVAQLIVITVFYNPEVICIGGGISEENWFINKVRETYKKTCREYLEADFITTE
                     INRCKHNNDANILGAVIKASI"
     gene            1676..3115
                     /locus_tag="NOB31_002615"
     CDS             1676..3115
                     /locus_tag="NOB31_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0974785.1"
                     /translation="MIYEELDKFQDDFLWGSASAAYQVEGAWDKDGKGESVWDVYTRQ
                     PGTTFKNTNGNIAVDHYNRYKEDVALMAEMGLKAYRFSIAWTRIYPNGRNEVNEEGLK
                     FYENLIDELIANNIQPIITLYHWDLPQHLQDLYGGWESREIIHDFNEYCVTLFKRFGN
                     KVKHWVSLNEQNIFVTLGYVTAMHPPAVKDQKRMLEANHIANLANATVIESFKKYVPD
                     GMIGPSFAFGPVYPFSCDPKDVLSAENAEDLNCNWWLDVYCKGKYPVFAFKYYERLGI
                     APTIEDGDLELLERVKPDFIGINYYQTSTVAFNPLDGVGQSEGINNTGKKGTTKESGL
                     PGVYKNAKNAHLETTNWDWAIDPTGLRIGLRRLTSKYNLPILITENGLGEFDKLEEDD
                     TVNDAHRIDYLSAHIKACKEAITDGVDLLGYCTWSFTDLLSWLNGYQKRYGFVYVDRD
                     ENDQKDLRRIKKNSFYWYKNVIRTNGEEL"
     gene            3163..3465
                     /locus_tag="NOB31_002616"
     CDS             3163..3465
                     /locus_tag="NOB31_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCI0974786.1"
                     /translation="MKKILLVCSAGMSTSLLVTKMRNSAKEKGIEVEIDALPVAEAST
                     AVDNVDIVLLGPQVRFQKGTVEKLVKGRIPVEVMDMRLYGMMNGKAILEDALQKIN"
     gene            3484..4848
                     /locus_tag="NOB31_002617"
     CDS             3484..4848
                     /locus_tag="NOB31_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0974787.1"
                     /translation="MSFMDKFQSAIERLLVPLSTKLNAQRHICAVRDAFILSFPLTMA
                     GSLMVLLNNVFLSADGFMFKILQFDKLFPGIVKFQAVFAPVVKGSADIFSILIVFLIA
                     RNLAKLMEGDDLLTGLTAISVYFIIYPDYFDNEGVNYLTNQYMGAQGLFVAILVGLLV
                     GELMSRLAKSDKLEIKMPEQVPPAVARSFKVLIPIIITTVFFSVLNYFVKMAAPGGLH
                     ELIYNIIQTPLTRMSQSLFSVIILALLSQLLWAMGIHGPNTIAAIRDTMFSEAGNANL
                     LHYAESGTTWGAPFPITYSGLATAFAEYGGSGATLGLIIAILIFSKNKESKSIGKLSF
                     VPGLFNINEMVIFGLPIILNPIYIIPFIIAPLVNIMIGYTAVMILKIMPPVTIGIPWT
                     TPGPLMPFLGTGGNIVALFVGFICLAVSVLIYSPFVIAANKAAIIEDEMENEIQSQEV
                     VESI"
     gene            4904..5218
                     /locus_tag="NOB31_002618"
     CDS             4904..5218
                     /locus_tag="NOB31_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCI0974788.1"
                     /translation="MEGIELTAFSIISNVGMAKSLAIEALRDARKGKYNEAEKKMAEA
                     SEYFVKGHHAHTSLIQKEAAGEKVELSLIIMHAEDQLMSTETTKLLIEEMIEMFKQLN
                     NK"
     gene            5552..6598
                     /locus_tag="NOB31_002619"
     CDS             5552..6598
                     /locus_tag="NOB31_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0974789.1"
                     /translation="MMNSTEIAKIAGVSRSTVSRVINNYSNVSEETREKVLRVIKEHE
                     YVPHASARMLAGSQNKVIGLFIIDLIHEEVGLKNRITKSPYYLEFTSSVIETASEMDY
                     LVLVHIIHSVAGYEKIKESFYNKTISGGIFIGQNDDDESIKTIIDRGYKVVLLDQSIR
                     PEDATYNQCMIVNADNYNGAYCATKYLIDKKHKQIAHITGGTVKFSSKDRIRGYKKAL
                     EDAGIEVNKNLIVNSEFVENAGYEAAKKLFNGNSEFSAIFASNDKIAFGAIKAIQERG
                     LKVPDDISVIGFDDIESSKYFNPPLTSMKMKLGEMADIATKSIVASIEGETKPSINVV
                     PVSLVERESCGILQ"
     gene            7210..7707
                     /locus_tag="NOB31_002620"
     CDS             7210..7707
                     /locus_tag="NOB31_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974790.1"
                     /translation="MKQRIGNNLALIYSGALLIQDILGYPLRLEHIQTVLINSYEQLI
                     VDTSLGSEQTVFDRVKTLLVMNSHKFLTNSDNKHTPSTIWGKVSIKKNGDIKVNIFPI
                     PFEDLLRREFQVKDLTYLFRQLLDSGNMCAEKGRRTKRIHMNRQVLPTYEILLPSSLK
                     SYFRL"
     gene            7750..7911
                     /locus_tag="NOB31_002621"
                     /pseudo
     CDS             7750..7911
                     /locus_tag="NOB31_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002816258.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         2816 a         1240 c         1684 g         2333 t
ORIGIN      
        1 gcaaccggag tttcttgatg aaaatatact tctatcatta caagctcgtt tggtgtaaga
       61 tgggtataag tcatttatgt tcactctcct tgtatgcttt agcgggtatt acgatttgag
      121 tgtaacataa atggcttttt tatttgtctc gcttaattat acaaacggcg tcattagaaa
      181 atgatggtaa attatttgat ggtaacggtg atgtaacaac ggtaatgaaa ttattgcttt
      241 aacagtttag cgtgataaaa atctatacct tcttaagttg atttattaac ttgagaaggt
      301 atttttttct gaaaaatgat aatgaaaatc aaaatgttca tttctatcaa ttttgaagtc
      361 aaaaaaataa agtacagccc agaaatttgc tctgtacttt aaaaaactag ttaaatgaag
      421 atgaaatcgc tcccttattt tttagtattg gtggaattaa aaggtacttt ttaaacaaaa
      481 actacacata aaaaataaaa aaaataaaaa aagtattgaa atgtaattgc tttcagtata
      541 tgctatatct ataaacgcgc gttcatggga tgttcatcgt ataaaaaaag gtggaaatga
      601 gcgtatcgtt tttcttttta acaaatcatg aacgcgcgtt tatgagtttg aatcaagctg
      661 caatataaga aggcaaactg caagaccttc attttaagga gaagtgttat ggggaaaata
      721 agtttaggaa tagacatagg agggacgttc attaagtatg cattaataga caagcaacat
      781 cgcatcaaag agaagtggaa agtcgaaacg gttaagtaca atacagccga cgaattttac
      841 gattatatat gttcaaatat aagaaatgta gatgaaattg acaaaatcgg tgtaagcgca
      901 cccggcctta ttgatgaaga ttcgaatgtt aaatcctatg ctgctcctaa cgtagctata
      961 atgtacggca caaatatcaa taatgagatc aacaaaagga caaataaaaa agtgtccgca
     1021 atcaatgatg caaaagcggc aggtttatgt gagtttaaaa ttggaaatgc aaagggatac
     1081 aaatcttcag cgtttttgat tataggtaca ggaacaggcg gatgcatatg cgacgaaaac
     1141 ggagttgtgt atggaaaaga ttcgtttgcg ggggaattcc ataatatgcc ttttgtaaac
     1201 gctgagatag gcggccttga taagatgggt gattatgctt cgataaccgg attggttaat
     1261 ttatacaata aaaaagctaa tcgggaggag caggttcagt atggaaatga ggtttgcaag
     1321 aagtacctaa acggaaatga atcagctgtg tcttcagtag atgaatggat aggaaacata
     1381 gtggctcaat taatagtaat caccgttttt tataatcctg aagtgatatg catcggtgga
     1441 ggaatatccg aagaaaactg gttcatcaat aaagtaagag aaacgtataa gaaaacctgt
     1501 agggagtatt tagaagcgga ttttattact accgaaatca atagatgcaa gcataataac
     1561 gatgccaaca tactgggtgc tgttataaaa gcttctatct aaaatacaca acagttttgt
     1621 ttcaagaaag aatgtttgaa aataaattta tattgaaaac gaaggagaag attcagtgat
     1681 atacgaagaa ttagacaaat tccaagatga tttcctatgg ggatcggcat ctgcagcgta
     1741 tcaggttgaa ggagcatggg acaaagatgg aaagggggaa agtgtatggg atgtgtacac
     1801 ccgccaaccg gggacaacat ttaagaatac aaacgggaat atcgcggtcg accattacaa
     1861 tagatacaaa gaagacgtag ctttaatggc tgaaatggga ttgaaagctt atagattctc
     1921 aattgcatgg acacgtattt atcccaatgg aagaaatgaa gtaaatgaag aaggcttaaa
     1981 attttatgaa aacttgatag atgaacttat cgcgaacaat atccaaccaa tcattacgtt
     2041 gtaccattgg gatttacctc aacatcttca agatttgtac ggcggatggg aatcaagaga
     2101 aatcattcat gattttaatg aatactgtgt aacgttattc aagagatttg ggaataaagt
     2161 taagcactgg gtatcattga atgaacaaaa tatatttgta acactaggtt acgtaaccgc
     2221 tatgcacccg ccagctgtta aagatcaaaa gagaatgctt gaggcgaatc atatagcgaa
     2281 cttagctaat gctaccgtaa ttgaatcctt caaaaaatat gttccagacg gtatgattgg
     2341 accaagcttt gcatttggac cagtttatcc attcagttgc gatccaaaag atgttttatc
     2401 cgcagaaaat gcagaggatt taaattgcaa ttggtggctc gatgtttatt gcaaaggtaa
     2461 atatccagtg ttcgctttta aatattacga aagacttggg atcgcaccca ctattgaaga
     2521 tggagatctt gaattgttgg aaagagtaaa accagatttt atcggaataa attattacca
     2581 aacaagcaca gttgcattca atccgcttga tggagtaggg caatcggaag gtatcaataa
     2641 cacaggtaaa aaaggcacca ctaaagaaag cggattaccc ggagtttata aaaatgcaaa
     2701 aaatgcacat ctggaaacaa caaattggga ctgggcaatt gatcctactg gtttaagaat
     2761 tggactaaga agattgacca gcaaatataa tcttccaata cttattacag aaaacgggct
     2821 tggagaattc gacaagcttg aagaagacga cactgtcaat gatgctcaca gaatcgatta
     2881 cttgagcgca catatcaagg cttgtaaaga agcaataaca gatggtgttg atcttctagg
     2941 ctactgcacg tggtcattta cagatttgtt aagctggttg aatggttatc aaaaacgcta
     3001 tggatttgtg tatgtggaca gagatgaaaa tgatcaaaaa gatttgagaa gaatcaaaaa
     3061 gaacagcttc tattggtaca aaaatgttat tcgcaccaat ggagaagagt tataagaatc
     3121 gttcacaatc aatgaatatg aaaaaacaag gagagataga ccatgaaaaa aattttacta
     3181 gtatgttcag caggaatgtc cacaagtttg cttgtgacca aaatgagaaa ctccgcaaag
     3241 gaaaaaggaa ttgaagtaga aatagatgct cttccagttg cagaggcaag tacggccgtt
     3301 gataatgtcg atatcgttct tttaggacca caagtgcgtt tccagaaagg gaccgttgaa
     3361 aaacttgtaa aaggcagaat tcccgtagaa gtgatggaca tgcggctgta tggaatgatg
     3421 aatggaaaag cgattttaga agatgcttta caaaaaataa actaggaaag gaggctaaaa
     3481 aaaatgagtt ttatggacaa atttcaaagt gctatagaaa gattgttagt gcctttatct
     3541 acaaagttga acgctcaaag acacatatgc gcagtaagag atgcttttat tttatcattc
     3601 ccattaacga tggcaggatc attgatggtg ttattgaata atgttttctt gtcagcagat
     3661 ggattcatgt ttaaaatctt gcaattcgat aaactttttc cgggtattgt taaattccaa
     3721 gcagtgttcg ctccagttgt taaaggttca gctgatattt tctcgattct gattgtgttt
     3781 ttgatagcca gaaaccttgc gaaactaatg gaaggcgatg atttgttgac aggtttgacc
     3841 gcaatctctg tttatttcat catctatcct gattatttcg ataatgaagg agtaaattat
     3901 ctaacaaatc aatatatggg cgcacaaggg ttgtttgtag caattttggt tgggctcttg
     3961 gtcggcgaac taatgtctag attagcaaaa tcagataagt tagaaattaa aatgccagaa
     4021 caagtacctc cagcagttgc aagatccttc aaagtgttga tcccgattat catcacgacg
     4081 gttttcttct ccgtcctcaa ctactttgta aaaatggctg caccgggcgg attacatgaa
     4141 ttaatttata acatcattca aacaccattg accagaatga gtcaaagttt attctcagtg
     4201 attattttag cattattatc tcaattgcta tgggctatgg gaatacacgg accaaatacg
     4261 attgcagcta ttcgagatac catgttctcg gaagccggaa acgcaaacct cttacattat
     4321 gctgaaagcg gtactacatg gggagcgcct tttccgataa cgtacagtgg tttagctact
     4381 gctttcgctg aatatggcgg ttcaggagcg acattgggtc taatcattgc tatattgatt
     4441 ttctcgaaaa ataaggaatc gaaaagtatt ggcaaacttt cttttgtacc cggtttgttc
     4501 aatataaacg aaatggttat ctttggttta ccgattattc tgaatccgat ttacattatt
     4561 ccatttatta ttgcgccact ggttaacatt atgattggct ataccgcagt tatgattctt
     4621 aagattatgc cgccggtaac gattggtatt ccttggacaa caccaggacc attgatgcct
     4681 ttcttgggta caggcggaaa tatcgtcgca ctgtttgtcg gattcatctg tcttgcggtg
     4741 agtgtattga tttactcgcc gtttgtaatc gcagcgaata aagcagcgat tattgaagat
     4801 gaaatggaga atgaaataca gtcacaagaa gtagtagaat cgatttaaaa aagctgcagt
     4861 acgctgagaa caaaccgaaa gattcaagat aggagattta cacatggaag gaattgaatt
     4921 aactgctttt agtataatca gtaatgttgg aatggccaaa tcattggcta ttgaagcatt
     4981 aagagatgcc agaaaaggaa agtacaatga agcagaaaag aaaatggctg aagcatcgga
     5041 atattttgtg aaaggccatc atgcacatac ttctttgata caaaaagaag ctgctggcga
     5101 aaaagttgaa ctttcgttaa taatcatgca cgcagaagat caattgatgt cgacggagac
     5161 aactaaatta ttaatcgaag aaatgataga aatgttcaaa cagttaaaca ataaataagt
     5221 gaacatgaaa gagaaaatat tagacgaact agaattgctt gcttacttta caggcagaat
     5281 ctgatgccag cagcaaaaca tagagcaccc aggatgaaat ataatcctgg gtgccttatt
     5341 tttagaacaa aacaccgggg tggtagtttg ttctgcggtt gaaggcattt gctgatggtt
     5401 tctgcatgaa aggtattgcc aaaagtctcc ttttgctgga atcctgaagc aggcagagtt
     5461 tttcgaaaaa cagaaaaaga ttgaaaaaaa tggacaaata atatagtgtt gcagtatgaa
     5521 cacgagttta cgaacgaaag gagatgcctt tatgatgaat agtactgaaa ttgcaaaaat
     5581 tgccggagta tcacgcagta ctgtatccag agtgataaat aattattcaa atgtctcgga
     5641 agaaacaaga gaaaaggttt taagagtaat taaggaacat gagtatgtgc cacatgcttc
     5701 agcaaggatg cttgcaggaa gccaaaataa ggtgatcggc ttatttatta tagacctgat
     5761 acatgaagaa gttggactaa aaaatagaat taccaaaagt ccgtattatc tagaatttac
     5821 tagttcagtg atagaaacag caagtgagat ggattacctg gttcttgtcc atattataca
     5881 tagcgtcgca ggctatgaaa aaattaaaga gagtttttat aataagacaa tttctggtgg
     5941 gattttcata ggccagaatg acgacgatga atcgataaaa acaatcattg atagagggta
     6001 taaagttgtg ctgctcgatc aatcaatcag acctgaagat gccacctata accagtgcat
     6061 gatagtgaat gcggacaatt acaacggcgc ttattgtgcg acaaaatatc tcatagataa
     6121 aaaacataaa caaatcgcac atattacagg cggtacggtc aaattctctt ctaaagacag
     6181 gataagagga tacaaaaaag cattagaaga tgcagggata gaagtaaata agaacttgat
     6241 tgtaaatagc gaatttgtgg aaaatgctgg atatgaggct gcgaaaaaat tatttaatgg
     6301 aaatagtgag ttttcggcta tttttgccag taatgataag atagcatttg gagcaatcaa
     6361 agctattcaa gaaagaggtc tcaaagttcc agatgacatc tctgttatag gatttgatga
     6421 tattgaatcg tctaaatatt ttaatccgcc attgacttct atgaaaatga agttaggaga
     6481 aatggctgat atcgccacaa agtcgattgt tgcatcgatt gaaggtgaaa cgaagccatc
     6541 tataaatgta gtacctgtct cattagtgga aagggagagt tgtgggattt tgcagtagca
     6601 aaacttgctg aattagttgg agctgattat ttgattattt tgattgaggt agacaatgtc
     6661 tgtgtctatg tcgacttgaa aagtaaagta cagcgcccaa aaatgctctg tactttaaat
     6721 ctcagcaaaa acaggaatat ttcccaaaca tctccttctt tgagtaatta tacaaaaatt
     6781 atgcagactt tcttttttca tgataagata atttaaaaag tttttaaacg atttctcctc
     6841 ctctttttct tatatcgggg gagcatattt ttttgtagac taggggatta taagttcagc
     6901 catcaatgtc tagctcccaa gtcctgacct agtgaaaaaa agataaattt gccccattgc
     6961 gcgcttcgct gctcattcag ggtcaaattt cctatttttt cataggtcaa ggcggacttg
     7021 tccgcttttc ttatattaag tttacaaagg atgcgaatca cgcagagaaa gttaaaagtc
     7081 tttcttctaa tacttttggt tggggtataa agttatttct tttgaaactc tttgaacaag
     7141 ggattgcaaa aattgaagca acttttgtcg aagctcaaaa aaatatgggc tgttttacct
     7201 gaacattctt tgaagcaacg cattggtaat aatctagctt tgatttatag tggagctctc
     7261 ctaattcaag atatactggg ctatccttta cgattagagc atatacagac ggtgcttatt
     7321 aattcgtacg aacagttaat cgtagatact agtttaggaa gtgagcaaac ggtatttgac
     7381 cgagtgaaaa cattgttggt gatgaatagc cataaatttt taacaaacag tgacaacaaa
     7441 catacgccca gtacgatttg gggaaaagta tcaattaaaa aaaatgggga tattaaggta
     7501 aatatttttc ctatcccgtt tgaggacttg ttaaggcgag aatttcaagt aaaggatcta
     7561 acctatcttt ttagacaatt gcttgattcg ggtaatatgt gtgcagaaaa agggagaaga
     7621 acgaaacgta ttcacatgaa tcgtcaagtt cttccaacat acgaaattct attaccttct
     7681 tcactcaaat cgtattttcg attgtaattt agaataaacc aaagtatgaa agtgaggcac
     7741 catgttatta agcaactgaa agatattcct attccaatgc ccgctatttc agaacaacaa
     7801 aaaatcggca ctttcttcaa acaactcgac gacaccatta cccttcacca acgtaagtta
     7861 gatttactaa aagaaacgaa aaaaggcttc ttacaaaaga tgtttgttta ggagggaaga
     7921 aaaatgaaaa ttagtcaccg tgaggaagcg gaagtcgaag aatgatggtg acactcacaa
     7981 tgtaataaaa ggttttatgc cccttgatct atcaactggg agaaaaattc gattttcaga
     8041 aattcagtat gaaggaattg gttttactct tat
//
LOCUS       DAIGSZ010000097         7625 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.101, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000097 DAIGSZ010000000
VERSION     DAIGSZ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.101"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(14..706)
                     /locus_tag="NOB31_002622"
     CDS             complement(14..706)
                     /locus_tag="NOB31_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCI0974791.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1143..1712)
                     /locus_tag="NOB31_002623"
     CDS             complement(1143..1712)
                     /locus_tag="NOB31_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0974792.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="NOB31_002624"
     CDS             complement(1786..2109)
                     /locus_tag="NOB31_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974793.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="NOB31_002625"
     CDS             complement(2263..3075)
                     /locus_tag="NOB31_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974794.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3429..4277
                     /locus_tag="NOB31_002626"
     CDS             3429..4277
                     /locus_tag="NOB31_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HCI0974795.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4422..5363
                     /locus_tag="NOB31_002627"
     CDS             4422..5363
                     /locus_tag="NOB31_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HCI0974796.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5353..7524
                     /locus_tag="NOB31_002628"
                     /pseudo
     CDS             5353..7524
                     /locus_tag="NOB31_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2272 a         1512 c         1371 g         2470 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acctatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aacgtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtgtgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataagg ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt aggatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcggcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcag gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagctt atgctttaat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggat ttagttcctt acgtgttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagaaac aaatcattca tactcttgtt gcacaaattc
     4261 ctattcctgt gaggtagatt gaggtagaca atggaaaaaa tcaaagatta tttcattaat
     4321 tttgtgttat ttctggtata tttcatcatt gtgctttttg ctcttgtatt caacaattct
     4381 ttaggctggt tcttgttggc cttttttact ctttatgtat catggagctt gatttcatta
     4441 agcagctttc taaagaaact ttcggttact tgtacattgc agccactcgt ttatcgcaaa
     4501 aaaagtatgc aggttatttt ttccatagca aaaaagagaa ctttttcttt acctctccct
     4561 cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa acaagagatt ttgattctta
     4621 caaataaacc gcaagaagtc caattgcttt ggcagccaaa agaaagagga tgccatgaaa
     4681 cattaactgt catttttaca gcctatgata gtctaggact tttcagaaaa agtgcaaaaa
     4741 gagagatctc ttttcctgtg actgttctgc ctgctttttg taagattcaa gcagaaaaat
     4801 tacagagagt tctggaaaaa aaacagcagc tgaacgcgta ccaaagaggt cttgattttc
     4861 gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg aatcgattgg aaattgtctg
     4921 ctcatactca agagtggtta taccgtgaat acgattatca agaagaagaa tgttctcctc
     4981 ttttttgctt ttggggttcg cccagtccaa aatttgaacc tctgctagac ttgtattttt
     5041 ctttatggca tttgagaaaa gaaaagcagc cggaacttct gatattaggc aaccgcgcct
     5101 ttcatggcaa agaccccggt catacctatt ttgcttcttt ggaagctggc gatgagaaaa
     5161 cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat cgtcctcttt gttcctgaga
     5221 attctcctga agtctcagaa gctattgaaa cattgtcaaa agatcgaacg gtttatcttg
     5281 tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga caagatatgt tcattgccag
     5341 gaggtgaatg gattgacgat taaacgggaa aaatggctgc gtggcgttta ctcctttgtg
     5401 atactaagtg taggtgctcc gatatttgta gtagctaatc aattgcaaaa cagctacctt
     5461 cttatcctaa ctattggtgt cctatgcctt attgtctgct gtattcctaa aaaatgggta
     5521 cgtttgctgc tttctttgcc agtaatgata ggttgtttgt ttttatattt tccttcgaag
     5581 acattttcca tattatggat cttacagttt ttttcgtcag ttacagagga attcttccat
     5641 ctatcccaag gtaaacttta ttatttgcca gaaaagacag ctttttttct cataatgttg
     5701 ctgatctatt tatttattac attgaccgtg gattacgact attggtacgc accctttctt
     5761 tctttgatgg cttacttcat gatgcttacc gtttttcgga aaaaagattt actgtacgaa
     5821 atgattgcgg tagtaactgt tttgttcgtg tatctggcag caaggcaatt tttctccatc
     5881 cggttgttgt cgagaaacac tcgattccag tcattgacta cagttctgct tatttgtttc
     5941 ttaactttta gcgctatctt gcctttatat cttccgaaag tacaccaatc tctcgaggaa
     6001 acgagtgaac cgatccgaga atatcttaat gatgaagggc tttatgacac actccatgag
     6061 tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga atgatgaaca gcttggtgga
     6121 cctttatatg ataatggcga agttgttttt acagcgaacc aaaaaggaaa tggctattgg
     6181 aagatcgaaa ataaaaatca ttacaccggt tctggatgaa tagaagatca ggacgcaccc
     6241 atccaaccaa tccaagaatt ccctgttgac atcacgagct accaaaccgt tatagaagac
     6301 aaagaaaaca ttacattgac cctaaaaaaa caagctttct taccttatcc ttatggaaat
     6361 actaccttga ctgatttttc attagctagt ggacaaacgc tttactattt gcctgaaagc
     6421 cagcgattca ttcctgtccc gaatgaatcg acacgttctg caactttaca aacagaaagg
     6481 ttagttttta cgagagaaga attaaaaagc agtcagttaa aagctgatga tttagaaaat
     6541 cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac gtattgagga cttggcggtc
     6601 gaattgacca aaaatgaagc aactttaatt cgtaaagtcg aagctgtcta acagtattta
     6661 aaaacaagcg gaaatttccg ctattccaaa acggataccg ggcatactcc aaaagaacac
     6721 gattatgtgg attatttcct ctttgattca aaagtcggct attgtgacaa cttttcaact
     6781 tctatggtcg tccttcttcg aacacttggt atcccagctc gctggacaaa aggttttaca
     6841 aatgggctca gaacaggcac agataatcaa gggaatgagg aatacagcat tctcaatagt
     6901 catgctcatt cttggccaga ggtatacttt cctggatttg gctggcttcc atttgaacca
     6961 accccttcat ttgccaatcc aatgggttca caaccagttg ctgaaacaac cgaaaccgtc
     7021 cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg cagaaactat ttccagtgag
     7081 agatctgagg tcattccatc agaagaaaca acactcacac cagcttataa aatcgtctta
     7141 ttcagccttg gagtgtgttt atccgtcttg ttgttctttc tattgttatt cagaaaatct
     7201 ctgcgctgga caagttatct tatctatctt catttttttg cttctactaa tacgattgca
     7261 tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc gcaaacccgc agaatctttg
     7321 caggaatata gcctgcgaat agaacaagaa ttcaagctag atctgcgttt cattcgatta
     7381 actactcaat atgaagcaga aatatatgga cgacaagcag atccggtaaa attcgataaa
     7441 aaaacctatt tagaaataac gcatataata agaaaaacgg tatacaaaaa aattctgaca
     7501 aaagggagcc gcttcaaaaa ataagataaa atttctggag aatctacttc tcgaatgccg
     7561 agaaccagct gattgagtat cgattactcg aaaaaaaggt tgtgacacgt tttttgtcac
     7621 aacct
//
LOCUS       DAIGSZ010000098         7597 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.102, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000098 DAIGSZ010000000
VERSION     DAIGSZ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.102"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(940..1353)
                     /locus_tag="NOB31_002629"
     CDS             complement(940..1353)
                     /locus_tag="NOB31_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HCI0974797.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1809..2294)
                     /locus_tag="NOB31_002630"
     CDS             complement(1809..2294)
                     /locus_tag="NOB31_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974798.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2433..2648)
                     /locus_tag="NOB31_002631"
     CDS             complement(2433..2648)
                     /locus_tag="NOB31_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HCI0974799.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2872..3672
                     /locus_tag="NOB31_002632"
     CDS             2872..3672
                     /locus_tag="NOB31_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0974800.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3691..5559
                     /locus_tag="NOB31_002633"
     CDS             3691..5559
                     /locus_tag="NOB31_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCI0974801.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5552..6043
                     /locus_tag="NOB31_002634"
     CDS             5552..6043
                     /locus_tag="NOB31_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCI0974802.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6031..6585
                     /gene="srlA"
                     /locus_tag="NOB31_002635"
     CDS             6031..6585
                     /gene="srlA"
                     /locus_tag="NOB31_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HCI0974803.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6603..>7597
                     /locus_tag="NOB31_002636"
     CDS             6603..>7597
                     /locus_tag="NOB31_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HCI0974804.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2234 t
ORIGIN      
        1 gttactatga ataacataat aagaaagtaa agtggattga tttgagatct ttttatactt
       61 caaaaaagat aacacccaac tttcaaaaat atgttttgga agttgggaca aacgagttaa
      121 tacattttaa tacattattt tttattcaaa aaaaatagca caatggcaaa gatcgtaaga
      181 gagatcataa gccccaatga atgactaaaa agaaaagcag aatcacatgc catatcatcc
      241 catatttctt caagaaaata aataagcggg aaaaagggaa ggaatagtag aacatcgatc
      301 cagcaccatt tttttcttct tttgaaataa cataaaacaa taaacatgaa cgtgcaggga
      361 agtaaaaaca aagctttact cataactaac aaaataccag ctccttttat ttttttctcc
      421 cccacattca aagagtaaca atggtatgta cttaataata gaaaaatgga tcaacttgta
      481 tgaataacag ctgaaaagat ctgcaccaaa taaaaaactt ccagccaaaa ctgactggaa
      541 gtttattttt ttctgaaata ttctaacaca aatatgaaaa agatggccga agctaataag
      601 ccgatttcgt agcaaaacaa tgagatacca gagtcgtaat aataaaatcc tctaatctta
      661 tggataaaat agatcatcgg acaagcagat aagagtaagt atttgttagg ccttttgaat
      721 aagtaaaaga aagcactggt cattatgata aatggtatcc aaaacaaaag tttacttaag
      781 acaatcaaat gatcaactcc catatttttt accaagagag atcataacat ctttatcgta
      841 aaaacaaaat atttttttgc tcattttgaa aatttaaaca tactcgttct tatccaaata
      901 tataaaaatc gcccctcatt catcgagagg cgataagttc taatttaact caattttttt
      961 tgtttctttt ggctgataag ctgttttagg taataccaat ttcagcacac cgtttttaaa
     1021 ggttccagtg attttttctt catcaacatt aggaagatag aatgaacgtt tgtaagagac
     1081 cgaatgtctt tctttccgta catagttgcc atcttcttta tcttctgtat gggactcatg
     1141 attggcggag atcgtcaaag tattatctga atattcaact gtcgtgtctt ctttgtcaca
     1201 gccaggcata tcagcagtta gtttgtattc tttttcattt tcgactaaat ctacttttgg
     1261 ataacttgaa acacctaaaa aatcattgaa tgctggacta aacacgtcat tgaaatcagg
     1321 gaacatgtcg cgaatgctag gtacatttgc catttttgat catcctttca ataagtattt
     1381 tttatttatc cctatttacg taataactct attttgaaaa aaatgcaagt ataatggtta
     1441 gctttgtgaa tatttcatct aatacgatac aaaggctatc tttctaattt gaaaaaggga
     1501 tcattaaaat aataagaaga aaatatgtca aaaggtaaaa aagtaaattc ttctatccaa
     1561 atatagaaaa attgaatcta gaaaaccgcc cgacaataaa tttcattaac tcagttgacc
     1621 gaaaatgaag tagataccaa aaatttatca agagagcaag tagagaagtg agtatattca
     1681 taagagaaat agctgtaacg aattattagg ttaatgcaaa tgcttattta tactccgtat
     1741 aactttctca gaaaaaatga taccaataat gacttgctag tactgtaaat ccgtataata
     1801 tcatctaatc aaaatggtgt tccatttgca tctgtcatcg taatcgatcc ttcgggtgac
     1861 actcgataaa aaccaacgct tccagatcct ccttgggaac ggatttgttt gctggaagct
     1921 gtgaacaaat aatctcgatc aattttttga taaaagctaa taacaatatc gtcactttgt
     1981 aattcggaac ggtgggcaat aagaaataga agtgctttgt cagagttttc taatggaaga
     2041 gaaggtacag tgctttcttg catttcagat gttgaagaaa tgctaaacga ctgaatactt
     2101 gattggctat gttgcgaatc tacattacca gtagaagtat tagtaatgga agtagtagaa
     2161 gtacttttag ttgaaccaac ctcagttgtt gaaatggctg ctgaagattc tttaacagaa
     2221 ttctttgttt tatatccaca ggcagaaaaa agtattacag ttcccaacaa gcctgcgtaa
     2281 atccctttat gcatgatagc tcctcctaaa atagattatc tttattcagt atatcactta
     2341 aacaaagaaa agcagatggt ttaaaatgaa aaaaccttcc caataaaggg aaggttcatg
     2401 aagataataa cttttttaat aattatagct ttctaatatc tttcatcaac ttttctagta
     2461 atcattggga aaaatttcaa gcagtagatc gcacaaatac ctacgacgat ataaatgatc
     2521 ttcgcaaaaa tagttgttga accaccagca atcatagcta ctaaatcaag ttcgaacaag
     2581 cctaccaaca gccagttcaa ccctcccaca atcaataaag ttaatgcaat agcatctaaa
     2641 gttttcatta gaattctcct ttcttaaatg ataaaacaat tatatatcaa aaagagaaac
     2701 attgcttata taacgctcag gaattttagc aatctatgca aaaagatgaa aatttttttt
     2761 gctcttccat tagtacacat tttttagctg aagctgtaaa tttcatgtct taattttttt
     2821 tagtgagctt ttatactgga tttgtaagaa aaaagaagga gaggatcaca tatgtcggat
     2881 tggttggata ttgcaggaaa agtagtaatt gtaactggag gttcctcagg aattggaaga
     2941 agtatcgtcg aaaatttgtt gaagcagaat gcacaagtag cgaattttga tgtaactgaa
     3001 tgccgtatac agcatgaaaa cctactatct ttaaaagtcg atgtgtcttc taaaacggac
     3061 atagaagaag ggatatataa agtaatgaaa catttcaaga cgatcgatgg tctagtcaat
     3121 aatgcaggaa taaatattcc ttctcttcta atagatagaa atcatccaaa aagcaagtat
     3181 gaattatcag aacaagtttt tgataagatg atcgctgtca atcaaaaaag tgtatatttg
     3241 atgagccaag cagttggaag aatcttggtg caaaagggat caggagtgat cgtgaatctt
     3301 tcttctgaat caggattgga aggatcagaa ggacagagct gttatgctgc tacaaaagca
     3361 gcgatgaaca gttttactcg ttcttgggca aaagagttag gaaagaggaa tgttcgtgtg
     3421 gtaggtgttg caccagggat actggaagaa accggtttga gaacacaaga atatgaagaa
     3481 gctctttctt atacgagagg tataagcgtc gaacagctga gaaacggtta cagtcgaaca
     3541 agtacgatcc ctctaggaag gagtggtaag ctgcaagaag tggcggatct agtctgctat
     3601 tatctttcag aaagatcaag ttatatcact ggagtcacga ctaatatttc aggaggtaaa
     3661 acaagaggat aaaggatagg ggggacgcac gtgacgctag taaacagatg gtaccaatta
     3721 ttgaaattac tagtcactca caagaaagtt tcaatccagg aagtgcaaaa agaaatcaaa
     3781 accagtaatc aaaccataaa aaaagatatt ggggagttga atgaagaaat tgccggtatt
     3841 gcaaaaatca tccaaaaaaa caaacatttt gaacttgaaa tttatgattt tgattttttt
     3901 gatgagatca tgcaaggaaa attgaaaaca gccagtgatt tcaattcggc atccaaaaga
     3961 atcgcttatt tactaaatag gctgatcgaa acagaggatt tcttacgtat ggatgatttg
     4021 tctgaagaag tcggtgtcag cagaggaaca gtggtcaagg atctaaagac attaaaagag
     4081 atgatcaatg attttgatgt aaagattaca ggcacaccaa ataaaggact aagaataata
     4141 ggagatgagc tagaattacg actactttta ttttattttg tttctcccta cttttcagag
     4201 acgaaaacag aacagtttct agaagaaaaa caagcaatca aacattttca gaagaagacg
     4261 aatgctagta aacaagaaat caccctttta acgaaagtta tcggtatttc tttgaataga
     4321 atctctagta actatctgtt gaagaagccc atcaatcgtt acagtgggtg ttttgaatat
     4381 atccaagaat tcaatgaact gatcaatcag ttggaagaaa tctatgaact aactttgagc
     4441 caatatgaaa aagattttat cagttttcct ttgaacatca tcaacacaag tataacgatg
     4501 ataaggaaag ctaactctga tttgcgctta tatttcgacc ccatgatgat gcgtattcga
     4561 cgattagatc tcattgatct ggatgagtcc ttcttatatc aagagatgaa acagcacctc
     4621 tctttattga taaatcgggt aatttttcgt tatcgattga ctgatttatt ttatggtgag
     4681 atagaaaaaa agtatccttt ttcttaccaa atcgctagcg aatgcataca agcattagaa
     4741 gctatcttgc aacataagat ctctaaagta gagatcagct acctaacgtt gtatttggag
     4801 ttagcatttc gatatcaaaa agagcatttt tcctctaaaa aagtagccat tgttcatacg
     4861 acaggaaaag gaacagcatt aatgatccaa agacaaatca aaaggatatt ggggagggat
     4921 atacaaataa cacatgtttc agaagaacaa tatgaaaaag tagatctaaa caaatatttc
     4981 gctgttttta caacgattcc gttaaaaaat gtaaatgaag agacaccggt gatccatttg
     5041 actaatcttt ttgatgactc ttggttaagg gcacaatggc aaaaagcaaa aaaaaagcga
     5101 ttagccgggt ttcattctac tgtttttttc tatcaaatat ggaaagaaaa aaagacgtat
     5161 caagaatatt taaacaaatt agtcgctcct ttgatcagag gctattatgt ggatgaagaa
     5221 tttgaaaaaa ggatcttgaa aagagaatat cagcaaagca catttgttaa caaagaattt
     5281 gcttttcctc acacaaccaa ccagctatct caacacattg ttttatcagt agggctaata
     5341 actgatcaag gtttagcaga aacaggagga aatggagtta tttttttatt tgccatacct
     5401 gaagaaatga cggctgaagt tgagaatgaa ttatttgagc tatacgatat cctatttgaa
     5461 ctcataaaaa tgggaataga tgagtttatt gaattagcac cgacacaaga atcattttta
     5521 aaactaatca aaagtaaagg agagagactt catgaatgat atgtatctat tcatagtttt
     5581 cgcagcttca gcttatgtgc tgcaagcagt tatcagttgg aagcaactaa agcatttcaa
     5641 tcaaacatat agcgaactgc gaagaaaagg aaaagtagcg attggtaaac gacctgggaa
     5701 aatccgttca ggcacgattg ttatgctagc tatagacgat catgatcaag ttttagaagt
     5761 cagaaaaatg caaggggtta catctttggc aaaatttcat tcattacctg tctatgcggg
     5821 tgaagatatc cattacatcg atcgttacca tccctcagtt cgagcggaag atcgtttgac
     5881 acaagcagct ttagaaaatg ccagagaagt atacttacga atagaggcag gaaatgaaaa
     5941 aagtgaacaa ccttcattgc cttttattgc tatgctcaat aattttcgga tatggaaaag
     6001 tacgatcaaa gaaaaaagga gtgacaaacg atggatatca taacaaaatt tgctgaggga
     6061 tttatgaggc tgttccaaac aggtgcagaa acattcataa gctggatgac aggaatcgta
     6121 ccagttgtct tgatgctgat ggttgcaatg aatacgctga ttgctttttt aggtgaagac
     6181 cgagtaacga aagtagccaa attatcagcg aaaaatccgc ttactcgtta ccttgtgtta
     6241 ccgttcttat ctgcttttat gttgggaaat cctatgtcat ttacaatggc tcgtttcctt
     6301 ccagaatact acaaaccaag ctattatgct gctcaagctc aattttgtca tacgagcaat
     6361 ggtgtattcc cccatattaa tcctggagaa ttgtttgtat ggatggggat tgctcaaggg
     6421 atcgaaacct tagggctaaa ttcgatggag ctggctatcc gatacttgct tgtgggactg
     6481 ctgatgaact ttattggtgg ttggataact gattttacta ctggatttgt atgcagacag
     6541 caaggaatcg ttcttagcaa aaaagtagag ctttcagttg attagagaaa ggagagtttt
     6601 aaatgtatgg tgatattaag atcgtaagag gaaacggcgg gtatggaggt cctttgatta
     6661 ttaggccgac aaaagataaa cacaagttca tctatgtcac aggtggaggt gagaggccaa
     6721 tgatcgtaga taaaatagaa gaactgacag gtatggagtc tatcaatggg ttcaaaacat
     6781 caatacctga tagtgaaatc gcgcttgcaa tcgttgactg tggagggact cttagatgtg
     6841 gaatttatcc taaaaaaggg ataccaacca tcaatatcgt ttccacagga aaaagtggcc
     6901 cattagcaca atatatcact gaagatattt atgtttcagc agtagggtta gaacaaatac
     6961 agccactaat ggaaactgat gataacaaag aaacagtaaa tactgcatct ccagataaaa
     7021 agtacaaata tgatacttct aaaaagataa ccgagcaaaa agcagagcag caaaactgga
     7081 tagcaaaaat tggaatgggc gcgggaaaag tagttgctac attcaatcaa tcagcaagag
     7141 aagcagtaga tacgatgatc cggacagtga tcccttttat ggctttcgtt tcccttttga
     7201 ttggtgtgat acaaggttct gggatcggta atgtatttgc taacattatg gcacctttag
     7261 caggaaatgc agttggatta acaatcattg gctttatttg ttcactgcca tttttatctc
     7321 ctttgcttgg tccaggggca gttattagcc aagtgattgg aacattgatc ggtgtagaga
     7381 ttgggaaagg aaatattcct ccccaattag cattaccggc actatttgct atcaatactc
     7441 aaaatgcatg tgattttatt ccagtcggtc taggtttgga agaagcaaaa gctgagacag
     7501 tagaagtagg tgtaccatca gttctttatt caagatttct taacggcatc ccacgagtta
     7561 tcattgcttg ggtagcaagt tttggattat atagctg
//
LOCUS       DAIGSZ010000099         6999 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.103, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000099 DAIGSZ010000000
VERSION     DAIGSZ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.103"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            318..677
                     /locus_tag="NOB31_002637"
                     /pseudo
     CDS             318..677
                     /locus_tag="NOB31_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(982..1944)
                     /locus_tag="NOB31_002638"
     CDS             complement(982..1944)
                     /locus_tag="NOB31_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0974805.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGESI"
     gene            complement(1946..3385)
                     /locus_tag="NOB31_002639"
     CDS             complement(1946..3385)
                     /locus_tag="NOB31_002639"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HCI0974806.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            3570..5516
                     /locus_tag="NOB31_002640"
     CDS             3570..5516
                     /locus_tag="NOB31_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HCI0974807.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5780..6652
                     /locus_tag="NOB31_002641"
     CDS             5780..6652
                     /locus_tag="NOB31_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCI0974808.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         2228 a         1211 c         1249 g         2311 t
ORIGIN      
        1 attataaata actcataaaa aatattttga ctttcaaaat cacttttgct accagaagtt
       61 gaggcgaagt gttttaagca tagttgtacc ctagtttgac cgttaaaaat aaataacgat
      121 cgctagagtg caactatgtt tgtttgctct accgtcagcg tcggcttggc ctctcacatc
      181 cattaccgtc gggatcatct ccgttacata cccttacaaa atacgccctg taagcattgc
      241 atgaaaccac cgtgcatttg caccgtattt ccgccctagc cgttcaaatc ggtcgctacc
      301 accattcaga aacacgtgcg gtaatggaag gtttggagga agctatccag accactaacg
      361 attgtcccta tcgtcgtacg tttcactcag atcaaggttg ggcgtatcaa atgaaagctt
      421 atagaaacaa attgaaggag tacaaaatct ttcaaagcct gtctcggaaa gggaactgct
      481 tagataattc acttatggag aatttttttg gcttattaaa acaagagatt tttcacggga
      541 aagtttataa ctgtttcgag gaattaaaat cagccatcga tagctatatc tattactaca
      601 ataatgaacg gataaaacag aaattaaact gtcaaagtcc cgtccaattt cgtaaaacaa
      661 ccgttacggt tgtgtaaaaa tatcatttta gagcatgaaa aaaggagtgg atttctccac
      721 tccaaaaaag tctaactttt gggggtcact acatttttga tcctttttat ttgattaatt
      781 atatccagct ggataataat tttgggggca acatttctat cttactatta tcttcctaaa
      841 gtagtagact ttcttattgg gaaaaattac aacaaaaagg agtggcttag ttgacaactc
      901 ctttttgttt acaaatcaat tggatatcta caaattgtat tttctaacgg attttataga
      961 cattaaaaaa ttaatttgac gttaaatact ttctccagaa agtattgaga ttggtaaaat
     1021 ataatcctta tttgtctttt cgcctttaat ttttttcaga agaatatcaa caataagact
     1081 tgcaatttca tcaattggtt gtcttattgt tgtcaattgt gggaaaaatt tctcaatgaa
     1141 agaggtacca tcgtatccaa taatttttaa atcttctggg atattaagtt taagttgatg
     1201 agcaattttc atagtgagaa tggctgttaa atcatcagaa acaaaaatac catctggttt
     1261 gtgatttata atagttgact ttatttccat ttcacgacgg atagtagaca gattattagg
     1321 aattttgaaa atttttccat ttggattttg aaaagaaaaa cctagtgcac gtaattctgt
     1381 gggagaatcc gtgttatcat ttcctgtaat cataatggta ttttgacaac catttttttg
     1441 taaagtctta gctgcaagtt ttcccccttc aaagttatct gaagaaacaa tggaaacatt
     1501 aggagctaaa tttctatcaa aagcaacaat aggtgctctc acacgctcat aatcagcaat
     1561 tccaagatta tggcttgatg agattatgcc atcaacttgg ttggcttcaa gcatttcaat
     1621 gtattctctc tctttagcag gatcattttg actattgcaa ataatcgttt tatatccatg
     1681 tttaaataac tctatttcga gatactcaat gagttcagag taaaagatat tactaatatt
     1741 aggaaaaata agaccaataa gctgaggtga ctttccttga agtccacgtg ctaaattatt
     1801 tggtttataa ccaagagttt tcatagcttc atgaactttt tgttttgttt tttctgataa
     1861 atatccctta ttattaatga cgcgtgaaac ggttgttggg ctaactccag ctaattcagc
     1921 gacatcagtt aattttgcta ccattttaat attttaattc aaagtatttt ccagtaggtt
     1981 cgcctgattt gatttgaata ccattttggt gattttcagg gaatacacga ctagtaaaca
     2041 ctttttctcc tttattaata aaaatctcaa tgattgagtt atctacaaaa atgttagcag
     2101 ttgtttcttt agtatcaatt gagcattcac gaatcgtacc aaagtcagtg gcatattgaa
     2161 tgcctgcttt gctgcgatct aaaataattt ttccttcttt ggtatctaca atcaagctaa
     2221 gtccatttcc tttactatca gagaaaagaa gtaactccga tttctgattt ggaggaaaag
     2281 ttagttcaag ctcataagta ttatttgttt ctgcttttgc tgtaaattgt tcagaactag
     2341 cacgtaatga tgtaatagct tctactggat attggtaaag tttaccatct tttattgaaa
     2401 gttcttttac aagactcatt gctccctgat aatcatactt atcagttgga taatcgatat
     2461 caggtagtcc aatccaactg acaatcagag cacgaccatc aggagtattg aatccttgag
     2521 tcgcatacgc ttcaaatcca taatcaagat tttgaatttc tgaagcgccc acaagtttta
     2581 ctttttctat gtcaagcgat tgacagatct taaaagtatt cggatagata ttcccataat
     2641 ttagctcaga tttatccaac ccttgaggac aataaatgag aacaggtttt ttgtctacaa
     2701 atactagatt tggacactca atcatgtatt ctgaaccagt gccgccaaaa tcaaggttgc
     2761 caacttcctc ccatgtttcc acgttattgt catccgcttt gtaaagtttg ataaagcctg
     2821 atttttctaa attttgtgct ccaacaatcg catacaattg tccttcataa ttaaacattt
     2881 gtggatcacg aaaatgatca gttacatcag caggtttatg aataagaaca ttctcacctt
     2941 tcgtaatgtt gtagtcttta tccatccatg ctccgatttg aagtgtatca cgttcccaat
     3001 tttcatttcg aacgtttcct gtatagagta agaatagatt cccctctatt tcatatgcag
     3061 aaccggaata agcgccgtgg ctatctcgtt ttgtgtctgg aagaagttct gctcctgtta
     3121 catgaaaatg aactaaatca tctgattcat tgtgtaccca ttctttcaac ccatgagcag
     3181 ctccaaatgg ccaattttga taaaaaagcg tatattttcc gttaaaaaaa gaaaaaccat
     3241 taggatcgtt taacaatcct gttttaggtt cgatatgata gctagcacgc caaggtgatc
     3301 gttttacatt atccttaatt ttatccatct catctttagt ccaatcagaa taagcacgat
     3361 atcgtatttc tcgaggtaag ttcatatttt actccttcaa tttatctttt tacaactagt
     3421 atggtaaacg ttttccgttg aaaaatcaat catttcattt aaaaaaataa actatatgac
     3481 aaacgtttga catattttta agatatgcta aaataaattt gcatttcagt gaaccgtttt
     3541 cacgtaaaaa taaaaaagga gtgattcgaa tgaattacag taaagtagct tccgacgtaa
     3601 tacaagcggt cggaaaagat aaccttattg cagctgcaca ctgcgctaca cgtcttcgtc
     3661 tcgtactaaa agatgacacg aaagtgaatc aaaaagcttt agacgaaaat ccagatgtga
     3721 aaagcacatt taaaattgat ggacaatatc aagtgattat cggtgcaggt gatgttaatt
     3781 tcgtttatga cgaacttatc aaaaaaactg gactttcgga aatttcaaca gatgatttaa
     3841 aacaaattgc tagtaaagat aaaaaattca accccattat ggcattaatt aaattattat
     3901 cagatatttt tgttccaatt atacctgccc ttgttgcagg tggtttatta atggcattac
     3961 aaaacttttt aacagctgct ggactttttg gaccaaaatc aattgaagaa atgtatcctg
     4021 cgattgaagg tatttcctca atgatccaac tgatgtccgc tgcaccattc atgttcttac
     4081 caattttagt aggtatttca gctgctaaac gttttggagc aaaccaattt cttggtgctg
     4141 caattggtat gatcatgaca acaccagatc ttggtggctc aactgaatat tggaatattt
     4201 ttggttatca tgtttcacaa acaaactatg cttatcaagt tattccagtt ttagcagctg
     4261 tttggatatt atctatatta gaaaaattct ttcataaaaa attgccatca tctattgact
     4321 ttacattcac gccattatta tcagtaatga ttactggatt tttgactttc acagttattg
     4381 gccctgtaat gttattgttg tctaatggaa ttacagacat tattgtttgg ctatataaca
     4441 ctactggatt tattggaatg ggtatttttg gaggaacata ttcacttata gtcatgactg
     4501 gtttacatca atcatttcca gctattgaaa ctcaattact ttcagcgtgg acaaatggta
     4561 tcggacatgg agactttatc tttgtagttg catctatggc aaacgttgct caaggtgctg
     4621 caacatttgc catttggttc ttaactaaaa attctaagac aaaaagtctt gcttcctctg
     4681 cgggtgtctc agcacttctt ggaattacag agcctgcctt gttcggagtt aacttaaaat
     4741 accgctttcc attcttttgt gctttaattg gttcaggaat tgctacagca gtagcaggat
     4801 tacttaaagt agttgctgtt tcacttggtt cagcaggttt cttgggattt ctttcaatta
     4861 atgcaacatc tattccattt tacgtattgt gtgaattgat tagctttgta gttgcttttg
     4921 caattactta cttctacggt aaaacaaaag ctgctggtat ctttaaagca gaagaaattg
     4981 ctgaacaaac accagttaat tcttcaaaag tagcaacaac agatccaata tctactgatg
     5041 ttgaatcaac acaaacaaaa gtttcatcag aaacaattgt tagtcccatt tctggtaaag
     5101 tgattagtct ttcttcagta aatgatccag tcttttcatc agaagctatg ggaaaaggga
     5161 ttgccattaa accaaatgga aacacggtcc attctccagt agatggtact attcaactca
     5221 cgtttgaaac tggacatgct tatggtatta aatcaaataa tggtgctgaa gttctaattc
     5281 atattggtat tgatactgta tcaatgggag gaaaaggatt tacacaaaaa gttactacta
     5341 atcaaaaagt tagaaaaggc gatattcttg gagcatttga ccgttcaatg attgagaaag
     5401 aaggtcttga tgatacaaca atgattattg tgaccaatac ttcggattat tcagaagtaa
     5461 atatagtagc tgaaaataca gtcactgagg gtactgattt acttgaaatc aaataaatat
     5521 atttccctga gtaaagatgg aattttcttt ccaaaatcaa ataatataga ttaatcaaat
     5581 atttgagaat aacattttat ttaatctttt catatatcaa ttgtatgaaa aattattaga
     5641 attttaaaaa atgataaaaa ttcaaaaaga aaaaatagta gttatttact tgtcatgtta
     5701 ctaaataaaa aaataattta aatatgatat atagtcattt atttagtgat ttcattctaa
     5761 aataaaggga gaaatgtcta tgctatacgg tgcaattgaa gcaggcggca caaaatttgt
     5821 gtgtgccatt ggcgatgaag aaatgacgat caaggaaaga gtgagctttc cgacaacgac
     5881 acctgaggaa acaatgcctt tagtcattga cttcttcaaa caataccaag cagatttagc
     5941 agggattggg attggctcat ttgggcctat cgatatccat cgcgattccg ccacttatgg
     6001 gtacattacc tcgaccccga aattggcatg gcaaaatttt gatttcatcg gtaccatgaa
     6061 aaaagaattt ccgatcccga tttcttggac aacagatgtc aatgcggctg cctatggtga
     6121 gtatgtcttc ggcagtggca aaggattgag cagtgtcgtt tactatacga tcggtacggg
     6181 tgttggcggc ggtgccttac aagaagggcg ctttatcgaa gggtttagtc atccagaaat
     6241 ggggcatatg ctcgtcgtcc ctcatccaaa agatgacttt gctggcagct gtccatttca
     6301 tggcaactgt ttagaaggga tggccgctgg acccgccatc gaaaaccgct tagggaaaaa
     6361 aggacaagag gttgcagaag atgatcctta ttgggaaatc gaagcctcct atattgctca
     6421 atgtgcctac aatacaacct tgatgttttc tccagatgtg atcatttttg gcggtggtgt
     6481 gatgaaacaa cgccatatgc tgcaaaacgt ccacgacgca tttgcaaaat tggtcaatgg
     6541 gtatgtcgaa acacctgagt taagcaaata tatcgtgacc ccagcattag aagacaacgc
     6601 tggaacgctc ggttgtttgg cattggctcg agaagcggtc ttacattcat aaacgaaaaa
     6661 aggctcttcg acatttagtg ttggtagaga aagatacaac tgaaaattta gtcataacca
     6721 gttaggcaga gtgcttaact ggtttttgtt ttacttggaa gatcaagcct tgaatgagat
     6781 aaattcttgc tcgaaagtta tggaaatttc gatagccgta ggccacttgt attgtgcaat
     6841 agttttttac aaaaaaaagg gggtgcggat atttttttgg acctttttaa caaataggtt
     6901 ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa agatagcagg
     6961 aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DAIGSZ010000100         6892 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.104, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000100 DAIGSZ010000000
VERSION     DAIGSZ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.104"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..227
                     /locus_tag="NOB31_002642"
     CDS             <1..227
                     /locus_tag="NOB31_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HCI0974809.1"
                     /translation="KTTEFDILHALMSTPNKVFSRSDLIEKVKGIEFDGLDRSIDSHI
                     KNLRHKIENDAKSPMYILTVHGTGYRFGGH"
     gene            227..574
                     /locus_tag="NOB31_002643"
     CDS             227..574
                     /locus_tag="NOB31_002643"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974810.1"
                     /translation="MRKRTIKTQLAVSFLAIATLIIGSISLVALSLMNNHFSKYVEER
                     QEDLLNQYVYTIDLLWLNSGETWNSEELAALSEKVLENNIYFSIEDEQGNMVWELTGK
                     DLKSAQEKLKKMH"
     gene            571..1620
                     /locus_tag="NOB31_002644"
     CDS             571..1620
                     /locus_tag="NOB31_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0974811.1"
                     /translation="MKVSEKNSVKLDETIEVKKKLINDGNEFGKVTFYYFGPFAYTEH
                     DALFISSMKQSLMYVAIAALLVSFILASWISARLGLPLKHVSDFTHKLTRGEYADKIP
                     QETSIIEINSLIDSLNDLSNQLEKQHGLRKRLTTDISHELRTPLATLKGNVEGMIDGV
                     WKITPERLQSCYDEIDRLTRLIGNIEIINKIEAKYDHLNKTEFNIYKLIESVIENFAS
                     KIESKNLHVEIQGDNINISADKDKMNQVVINLLNNAIKFTQKEGTIKFSISKNKDHVL
                     LIVEDNGIGIEKDQQLHIFDRFYMADPSRSRALGGQGIGLAIVKSVIEAHKGSITVKS
                     KLGLGTKFVIKLPFQ"
     gene            1635..1841
                     /locus_tag="NOB31_002645"
     CDS             1635..1841
                     /locus_tag="NOB31_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974812.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            1862..2458
                     /locus_tag="NOB31_002646"
     CDS             1862..2458
                     /locus_tag="NOB31_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HCI0974813.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
     gene            3410..4009
                     /locus_tag="NOB31_002647"
     CDS             3410..4009
                     /locus_tag="NOB31_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0974814.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            4058..4774
                     /locus_tag="NOB31_002648"
     CDS             4058..4774
                     /locus_tag="NOB31_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HCI0974815.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            4788..5567
                     /locus_tag="NOB31_002649"
     CDS             4788..5567
                     /locus_tag="NOB31_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HCI0974816.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
     gene            5650..6006
                     /locus_tag="NOB31_002650"
     CDS             5650..6006
                     /locus_tag="NOB31_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI0974817.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            5996..6262
                     /locus_tag="NOB31_002651"
     CDS             5996..6262
                     /locus_tag="NOB31_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0974818.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            6421..6699
                     /locus_tag="NOB31_002652"
     CDS             6421..6699
                     /locus_tag="NOB31_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974819.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
     gene            complement(6696..>6892)
                     /locus_tag="NOB31_002653"
     CDS             complement(6696..>6892)
                     /locus_tag="NOB31_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI0974820.1"
                     /translation="NNLIEQDHRSIKRRHKLYQSLRTASTTIKGMETIRGIYKKSRKE
                     GTLFGFSVCTEIRILLGIPA"
BASE COUNT         2534 a          959 c         1335 g         2064 t
ORIGIN      
        1 ttaaaacaac tgaatttgat attctacacg ctctaatgtc cacacctaat aaagtctttt
       61 ctcgtagtga tttgatagag aaagttaagg gaatagaatt tgatggacta gataggagca
      121 tcgattctca tataaaaaac ttaagacata aaattgagaa tgatgctaaa tcacctatgt
      181 atattttgac agtccatggt acaggataca gatttggtgg ccactaatga gaaaaagaac
      241 gataaaaact caattagctg tttccttttt agcaatcgca acattaataa taggatcgat
      301 tagtttagtc gcattaagtt tgatgaacaa tcattttagt aaatacgtgg aagagcggca
      361 agaagatttg ttgaatcagt atgtatatac aattgattta ttgtggttaa atagtgggga
      421 aacatggaat agtgaagaac ttgcagcact atctgagaaa gtattagaga ataatattta
      481 tttttctata gaagacgaac aaggcaacat ggtttgggaa cttactggaa aagatttgaa
      541 gtcagcacag gagaaactga aaaaaatgca ttgaaagttt ctgagaaaaa cagtgtgaaa
      601 ctagacgaaa caatagaagt gaaaaagaag ttaattaatg atggaaacga gtttggaaaa
      661 gtaacgtttt attatttcgg accttttgct tatacagagc acgatgcctt gtttatctcc
      721 agtatgaaac aaagtttaat gtatgttgca attgcagctc ttcttgtatc attcatactt
      781 gcttcgtgga tctctgctag attaggattg ccactaaagc atgtaagcga ttttacacat
      841 aaattaactc gtggggaata tgctgataaa atcccacaag aaacttcaat tattgaaata
      901 aattccttaa ttgattccct aaatgattta agtaatcagt tggagaaaca gcatgggctt
      961 cgaaaaagat taactaccga tatttcacat gaattaagaa ctccattagc tacgcttaaa
     1021 ggcaatgtgg aaggaatgat tgacggagtc tggaaaataa ctcccgagcg cctacaatct
     1081 tgttatgacg aaatagatcg tctaactcgt ttaattggaa atatagaaat aatcaacaaa
     1141 attgaagcaa aatatgatca tttaaataaa actgagttta acatatataa gttgattgaa
     1201 tccgttattg aaaatttcgc cagcaaaatt gagtcaaaaa accttcatgt tgaaatccaa
     1261 ggggataaca tcaatatatc tgcagataaa gataaaatga accaagttgt tatcaatctt
     1321 ttgaataatg ctattaaatt tacgcaaaag gagggaacca ttaagttttc tataagtaaa
     1381 aataaagacc atgttctttt aattgttgaa gacaacggca tcggtataga aaaagatcag
     1441 caacttcata tttttgatag attttatatg gctgacccct ccagaagtag agctttaggg
     1501 gggcaaggta tcggattagc tattgtaaag agcgttattg aagcgcataa aggtagtata
     1561 actgtaaaaa gtaaattagg tctaggaact aaatttgtta taaagttacc atttcaataa
     1621 aggaggagag ttatttgttt caaaaacaga taaaaattgc taaactagta tgtgaatgtt
     1681 gggcaaaaaa aatatttttt caactgattt cgatagatag tgtcgaaaaa gttcatttag
     1741 atatcttatc aaattctgta gtaatctttt ctaagaagga cttatcaata gctacaatta
     1801 aaaaagaagt ttttggatta caaatttatg agatgaccta aatgtgatta attaaaggag
     1861 gatgaagaca gtgaaaaaga tgacaaaatt agtatttgca agtcttggaa ttattgtatt
     1921 tttaggagcg tgtagcaatc aaagtgaatc gaataattct aatagcacaa acgaggaatc
     1981 gacttctaca gcgtctagtg aaatgaatag tatggaggga atgaatcacg aaggtatggt
     2041 tccttcttca atgaaagatg ctgcgaaccc taaattcccg gtgggaagta atgttatact
     2101 gctaggcgat catatggaag ggatgaaagg tgcaaatgct caagttgtag gggcctttga
     2161 tactacaatg tatgaagtaa gctatgagcc aaaaactggg ggaccaatgg ttaacaatca
     2221 tcgatgggta gtacaagaag agttaaaaga tactgagact gtagcaaatg agggcgatac
     2281 tgttatcttg aatgccgatc acatggatgg gatgatggga gctgaagcaa aagtagataa
     2341 atctattaca ggaactgttt acgttgttaa ttacactcca accgatggtc aagaagaagt
     2401 taagaatcat atgtgggtaa ctgaagatga gatggaatat gacgaaaata atgagtaatt
     2461 ttatatacta aaccaacaag ctggtacatg gtcttcgtat tctcaacatg aggaatatga
     2521 gctctttgtt aataaggact gatgagttgt gcaaaatcaa atctgggtca gaacgaacct
     2581 cattctggct cagatttttg gctcttcgac atttagtgct ggtagagaga caactgaaaa
     2641 tttagtcata accagttagg cagagtgctt aactggtttt tgttcgcatt tattattctt
     2701 ttgatattgg ctgcttgccc ttcaatttta tttggtttct taatcaactc ttcatataac
     2761 cccaaatcat atattaatga ggtgcctcct attcctataa atctatctct tctttaatag
     2821 tatgagaaaa gtctactctt gtagatttaa attgtcaaca aaaaatttac agatgtaaat
     2881 gataagttga atagagaaag ataaattatt tttttggtat tcatataagg ttaattatgt
     2941 attatcacaa aatgattgtt gtcgaataac taaaagtgtc aaaacaatga tgaaatcatt
     3001 tagttcttat aaattagaca agagaaaata aatattccat atctacttta ttggatccat
     3061 aacatgacta aattctgaat actttttaaa gcttatcatt tggtaaaact gaatataagt
     3121 taattatata gactgaaaat tttgaatttt cagaatagaa taacttaaaa gtactgacaa
     3181 attttttaaa ggggcaatat taatgttctg agataatcaa atcttaccga aaatatcaaa
     3241 agtccaatgt gacacaattg gattttgtca cattcgttaa aatcgctcca tccttagagg
     3301 ctctaatagg aaatcacttt tcttttagcg ccttttttct atagcttgtt taaatgtgac
     3361 ttattatctg ttataatcgt attaagtaac atttgagagg tgtctaaaaa tgaaaagcgt
     3421 ggaaccgatt cgcgacaaaa aaaagatcga tgccatgaag gccattttgg cttccggaaa
     3481 atatgggcaa cgaaatttgg tgcttttttc gatcgggatc aatacagcct atcgaatctc
     3541 cgatttaaga cagttaaaat taagggatgt gctagaaatt tcccgtgggc gggtgatcgt
     3601 caaagaacgt ctggccatga aggaacaaaa aacggccaaa cacaattcgg tcttcatttc
     3661 gaacaaattg cgaaaagtga ttcttgatta tgttcaatcc gaatttcctg agcagttgca
     3721 agcacaagac ttcagcaagt atttgtttcc aagtcgaaaa ggagcagata cgcctttgac
     3781 ccgacaaagc ctttggcgga tcattcatga agcaggaact gcagttgggt taaaagaaat
     3841 tggtccccat tcgatgcgta agacctttgg ctatttttta tacaagcaag gaaccaaaac
     3901 agagatcatt cagtcgctgc taaaccattc ttcacaacgg gagaccttac gctatattgg
     3961 aatcacccag gaagacaaag atactgcagt aaagagtttg gatttatgac agaataatgc
     4021 cctatataat agaaggaaaa attcaagagg tgagaaaatg aacgaagaaa agcagcctaa
     4081 ctttcctgat aaatatcact tatctcgcaa agagtctgtg tatttattga agaaaaacat
     4141 tgtagaactg gtgtataatg cggggaaatt tgaagggtta aatacaacgt tgttacaaac
     4201 agaagggatt attaagtata atcgggccaa caacgtggct gtagatgatg tcctgaccgt
     4261 cgttaactta aaaagaggct ttgaaatgct tttaaatgac gtacaggagc ccctgttaga
     4321 gacaagtaag cggattaatc ggatcgttgc agcagaggat gcgctttttc ccggtgaaat
     4381 acgaaccggt ggggtagaat tatcgacgat tcaaggaaga tatgtgccac caatgttaac
     4441 tgaagacgag gtaaacaatc aatatggtga gataatgaat caagagatat cagatacgga
     4501 aaaagccctg cgactgtttc tattcatttc gaaaaatcaa atattctgga atggtaatgt
     4561 gggtacagcc ttgttgattg cgaataagat tatgtttagc aacggtttag gactattatc
     4621 aatacccgaa aatgtattta tgaaatttaa cgaactttta tcaaagtatt gcaacagtaa
     4681 tctattagtc aatgagtcaa atattatatc atttttatat gaacagtgta tctttggtat
     4741 taattatttg aaaataatcc aacatacaat ttaagaggta taagtaaatg atgactatag
     4801 acgaagcaaa acaattagca acttattttt cagttggttc agcgggatat attttagact
     4861 ttactaatgt aacgtggaac atatttacaa agaaaatcgt agggattgaa atacaaaatc
     4921 attatggggg ctcaaaggga gtatcctttc aaaagtttct gcttgacgat caatttgatg
     4981 attcgttaaa gaatcggtta atccaatctt taaaaggtat tatggatcga gataaaaaat
     5041 atgaatctac tgaaatgaat cccatagttc agttgctttt tgaggaagta tttaaagaag
     5101 atacttcaac tgcattaaga aaaatgaaat tttcaagcga gattgattta ctttatattc
     5161 ggcagctacc cattaggatt caaacagata ttaaaaacaa ggattttgac tctgttttga
     5221 caaaagcaaa tactttaata gatgaagttc taaaatttat tattgaaaat accgaaggac
     5281 cgagtgttaa tattaattta tttaagtcaa aagaattaag aaaagaagta tttggccgcc
     5341 tcaatattaa aactgaaaaa gatatggata atagaatcaa agcccttgtt ggagcactca
     5401 atacattatc agataaaata ctcgaaatga gaaatagtca aggagatgct catgcacatg
     5461 gctcaaatag aatagtaatt aaggaagaag aagcaattct tgttgcaaat tcttctatgg
     5521 ttttgtgcga gtatgtgttt actaagtata aaggattaaa tagataataa aatgcatatt
     5581 ttatagtata caattcgaat ttttatgtta tatactataa tataaaatca atatatgata
     5641 taattgggta tggaaaaaat atcttttgaa acatttaaaa gacccaatgg tcatgatgaa
     5701 tttttagaat ggttggaaac attaccaaaa aaagatagtg cgaagctttt acgtacaata
     5761 gaagaaacag aaaagaatgg gatgctagta gctcaacggt tgaaatgggt gaaaaaatta
     5821 gacactaatt tgtacgaatt aagaagtaag gtaggatcaa acatccaaag agccatctat
     5881 ttccatgtgg acaatggaag gtatgtcatt actcacggat ttactaaaaa aacggagaaa
     5941 acaccaataa ctgaactcaa gcatgcaaaa gaacttagag aggagtggtt cacaaatgat
     6001 gattaaaaaa ttgattgaag aaaagaaaaa agataaagat tttgcagaag catatgaccg
     6061 tgaaggaaga aaactcgaaa ctgcggttgc tctttatcat gctcgggagg aagcagggct
     6121 aactcaagcg gagcttgcac aaaaagcaca tacaactcaa tctactattg ctcgaattga
     6181 gagaggggat aacgtatctt tcgataaact tgatgatatc gccagggcat taggtaaaaa
     6241 gctggtagta gaatttgctt aaaagcgagt tgaaaatata tctataatag gctcctaact
     6301 aatcaattag tttagtgggc ctttttttac tagatagata aaggttgtac tatagtgtaa
     6361 aagacaataa attttatact aaaattactt taaagagaac tagagagaaa ggtacaataa
     6421 atgaaaacca taaatcttat aaaagtattt atagcatcac caggtgatat agcagcaaaa
     6481 aggaatgaag tagaagaaac catatataga tggaatatag aaaatacaga taatacaaaa
     6541 gtgattttga tgcctatacg atgggaaact aatgcgattc ctacttatgt aaataatagc
     6601 tctgggcaaa gtgttattaa taaacaaatt gtagaaaata gggttctgct gcaaagtttt
     6661 aaaaataaaa tcagtttttg tattatttct tcattttaag ctggaattcc caataatatc
     6721 ctgatttcag tgcagactga aaagccgaag agagtgcctt cttttcggct tttcttgtag
     6781 attcctcgaa tggtttccat ccctttaatt gtggtggaag ctgtacgtag actttgatac
     6841 aatttatgtc gacgttttat cgatcgatga tcttgttcta ttaaattgtt aa
//
LOCUS       DAIGSZ010000101         6230 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.105, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000101 DAIGSZ010000000
VERSION     DAIGSZ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.105"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            133..633
                     /locus_tag="NOB31_002654"
     CDS             133..633
                     /locus_tag="NOB31_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCI0974821.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            730..2577
                     /locus_tag="NOB31_002655"
     CDS             730..2577
                     /locus_tag="NOB31_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HCI0974822.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2580..3476
                     /locus_tag="NOB31_002656"
     CDS             2580..3476
                     /locus_tag="NOB31_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0974823.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3526..3915
                     /locus_tag="NOB31_002657"
     CDS             3526..3915
                     /locus_tag="NOB31_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCI0974824.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3902..>6230
                     /locus_tag="NOB31_002658"
     CDS             3902..>6230
                     /locus_tag="NOB31_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCI0974825.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2106 a          925 c         1336 g         1863 t
ORIGIN      
        1 gagttttcca aactgattgg cttcttggtg attgctttga ttgcggtagg tctggtcttt
       61 aatgcttctg gtgtgaagga tgtcttactc aatttgttta accgaattgt cggtgcctga
      121 gggggaatca caatggaaca gatacgtgtt tatattgcga accttggaaa atacaatgaa
      181 ggtgagttgg tgggggcatg gtttacccca cccgtcgatt ttgatgaagt gaaagaacgg
      241 attggattaa atgacgaata tgaagagtac gcaattcatg attatgaact gccttttgag
      301 attgatgagt atacaccaat tgaggaaatt aatcggttgt gtggtttagc ggaagagctt
      361 aaaggaacgc caattggtga ggtcgcttca gagattcaac atgccttctt caattctttc
      421 gaggaaatgg tagagcatgt ggatgatatc atctattatc ccgattgtaa tgacatgagt
      481 gatgtagcgt attacttgat tgtagaagct ggtgatttag gcgaagtacc agaacacttg
      541 aagacgtata ttgattttga tgcgtgtggt cgagacttgg agattggcgg gaattatttg
      601 gttacgagtc gaggggtttt tgaactaatg taaatcattt gttagaattg accagaaatt
      661 tctatcgtac ttttactttt ctatttgata tactgaaata gaaaatattt gttgataggg
      721 gtgttactaa tggttggcaa taagtggtac aaatgtgatc ttcatattca ttcaactgcg
      781 agtcagtgct ttcaggataa aaaggttact gctaaggaat gggtagaaga atgtttaaac
      841 aaaggactcg attgtgttgc attaactgat cacaatacag gggaaaatat tgatgaatat
      901 aagaaagtgg ctatcgaaaa tggcttagat ttttttcctg gagtggaatt aacgtgtgga
      961 gaaaatggaa ctcatttact agtcctattt gataaaagtg catgtacaaa tgatatctct
     1021 gatttcttaa ccaagatggg tataaaaaga gaggattggg ccagcgctgc agcttgctca
     1081 atgaaatcag ttttagaagt tattgatttt gctgagcacg agggcttgct cgttattcct
     1141 gcacatatag atgagtttaa tggaatttct tcagcaaaat ttggaaatct aggaaagata
     1201 tttgaatcag aaaatatata tgcagtacag acggttcaaa aagaattttt tgaaaatcgc
     1261 tcacaaatga ttccctcatc taagcgtgac actatctatg atagtgtgaa tgccagatat
     1321 gatggtagag ttggaaaaga tactttggaa tcttggtata aatcagttgt tgaggcagaa
     1381 aaaaataata tgacatttct tagcttttct gataacccac actcgaaagg aaattcaaaa
     1441 catggacttt ggggaatagg cacaagatat tcctatataa aaatgaagga cgaacctgac
     1501 ttgggatcac ttcgcgatgc tttaatgcta ggcgaaactc gagttcattc tgatttttct
     1561 aatttctcca ttaatgaaaa tgaagtttta ttggaaaaat taagcttttc tgggaccact
     1621 cttagcacaa aagaagttgt agtcgaattc agcgataatt taacttcaat tattggagga
     1681 agaggaacag gcaaatcttg tattacaaga ttcttggtct atgtccttgg aaaggaagca
     1741 gaacttgatc aattttctga aatacaaagt gattatcaga actttgcaca aattgaacat
     1801 aatggctctg gaatattttt gaaggataca attgtgaaac tgaatatttt ctataagggg
     1861 acaaaatatc aaataataag aacacaggat agacattcta tttatgaatt tacacaagag
     1921 aatggtctgg ttgaaaaaga aacagaacgg ttgagaatga tttccgataa ggtgagtata
     1981 tactctcaaa aacaaattta tgaaatttca aaaaatcaaa ctagtatact agaattacta
     2041 gatggatata actctgattt gatttcagag tataaaaatg agattgaaac atgtgtaaac
     2101 gaaataagaa aattaaattg ggatattgtt tctgtgaaaa aagaaataca agataaggcg
     2161 aaggtagagc ttgaaattga agatttaaaa aaacaagtag aaaagctatc tcataagagt
     2221 tataaagatg tttatgatga gtattcaaaa gagacagata tttataggga actgaaacgt
     2281 gatgtggagg cacttaagga aattcccaaa aatctaactg atagtgttga caaaattgac
     2341 tttggcaatg gtataaaagt tacagacgaa attgatgaac accgcggaga attgattaag
     2401 aatttagtga ccaatcgggc taagattcaa acaataatta atgaaatgtc agatgaaatt
     2461 gatagttata gagcagagct gaataaatca gattggaaag ttaactataa tgaggtttca
     2521 aagaggtatc aaagaggtat caaaaactta gtgaagagtt atctcaagat gaattaaaaa
     2581 tgttacaaaa ccttgattct ttatatcaat ctttatcaaa aactgaagag cgattggaag
     2641 aaattattca acaagaaata aagcttaaag attaccaagt tgaggttgac tcagcaatgt
     2701 caagaatgaa taaatcatat caaaatctct attctgagag aagtagttcc tcgcgcgaaa
     2761 ttttttctga tattacagga atagaggcta ctattcaacc aaatagggat ttcaataatt
     2821 atgttaaaga gctcagagct tgtattaata aggaggacac ttttgacagt gagtttggat
     2881 ctcttattga taagctgaca aaaaattcca ttactaatca agatatatat aatgacatac
     2941 ttgatataag agttagtggg gaaagtagta ttttttcaga taaaaaatta atcaattcta
     3001 taagaaaatt gaatgatgca caagttcttg aattacaaac ccttaagcca aatgatttag
     3061 tagttatccg acttgaacta aatggaaaaa aagttagttt atcgaatgct agtgctggtc
     3121 aaaagacatc tgcaattctt tctatgattt tggcgtatgg aaattcacca ctcatattgg
     3181 atcagcctga agatgatttg gatagtcaat taattaataa cttaatcgta agaagtatca
     3241 ttacaaaaaa ggaaaacaga caaattttaa ttgtaactca taatgcaaat atcccagtta
     3301 atggtgattc agaatggttg attagcatgg gagattcaaa agaaatatcg gctgatcagt
     3361 gcgggtcggt agatgaaccc aatatcaagc caagaatatg tactgtgatg gaaggtggcg
     3421 aggatgcttt tacaaataga gcgaaacgct atggttttaa acaaattgta gaataacact
     3481 agagggtgag acatattatt atgtccgccc tttttaggag gaaaaatgaa aaaaataaaa
     3541 agctatacca gtatctgggc agttgaaaaa gtcatttacg caatcaatga ttttcagttg
     3601 ccttttcctg tgacttttaa ccaaatggct tggttcgttt tatctttact gtttgtcatc
     3661 gtatttgccc atgtgcctcc actatctatg atagaggagg tctttttaaa atacttaggc
     3721 ataccggtgg ctgtcacttg gtttatgtcg caaaagacgt ttgatggcaa gaaaccactg
     3781 ggatttttac gatcctttat cagctatcac ttgcgattta aggtgacttt tgcaggaaag
     3841 aaagtcaaag aacagaagaa acgatgggat gaacccagta ctcttgtaag gagtgtgaac
     3901 tatgtatccg attaagtata ttgaaaataa tctcgtcttt aaccaagaag gcgagtgttt
     3961 tgcctactat gaattagtgc cttacaatta ctcctttttg tcacccgaac agaaatttca
     4021 agtgcatgat aactttcgcc aactaattgc gcaaaatcgt gaaggcaaga tccatgcgtt
     4081 acaaattgcc acagaaagta gtattcgcgc cacacaagaa cgatcaaaaa aagaaattac
     4141 cggtagactc aaagaagtag cgaaacaacg aattgatata cagacagatg cattagtatc
     4201 catgattggc gatagtcaga ttgattatcg cttttttatt ggctttaaac taattgcgac
     4261 agatgaagaa gtcaatctaa agagtctcaa gaaatctttc ttttctgggc ttcaagaatt
     4321 tgtctatgga gtgaatcatc atttgatggg cgattttgtt tccttatcca atgaagaaat
     4381 tcgctgctat tctaagcttg aaaaattaat ggaaagcaaa ttggctcgaa gatttaaagt
     4441 caggcgagtc acaccgagtg acctgacgta tttgattgaa catatttatg gcgaaaaagg
     4501 gataccgttt gaagaatacg aatttcagct accaaagaaa aagctaaaat cagaaacact
     4561 ggtgaaacgt tatgacttat tacgtccaaa tcgttgttta attgaagaaa aaccaaggtg
     4621 cttacggatg gaacatgaga atcatgagtc gtacgtagcg tatttaacaa ttaatacaat
     4681 tgtgggggag atggaatttc cttcctcaga acttttctat taccagcaac aacaatttac
     4741 attcccaatc gacacaagta tgaatgtaga gattgtgacg aataaaaagg ctttagctac
     4801 cgttcgtaat aagaaaaaag aactgaaaga tttagacaat catgcttacc aatctgacaa
     4861 tgaaacgaat tccaatgtct tagatgcttt ggattccgtg gatgaattgg aaaccacctt
     4921 ggatcagtca aaagaatcta tgtacaaact gagttatgtg gttcgagtga gtgccgaatc
     4981 agtggatgaa ctaaagcgac gctgtgatga agtgctcgat ttttatgatg ataccaatgt
     5041 aaaactagtc cggccctttg gcgatatgat ggggctacat gaagaattct taccctcaag
     5101 taaacgatat atgaacgact atattcagta tgttacgtct gattttttgg cggggcttgg
     5161 ttttggggct actcagatgc taggagaatt agaagggatt tactttggct acaatgtgga
     5221 tacaggtcgt aatgtttacc tgaaaccggc attggcttca caaggagtca agggttcagt
     5281 aaccaatgcg ctggccgccg ctttcctggg ttctcttggt ggaggtaaat cctttagtaa
     5341 caatctctta gtctactatg ctgttttgtt cggtggtcaa gctgtgattg tcgatccaaa
     5401 aggggagcga ggagggtgga aagaaacctt gccagaaatt gcggatgaaa tcagtatcct
     5461 caacttgacg agtaagtcag aaaatcaagg tctgcttgat ccttatgtga ttatgaagaa
     5521 aaagaaagac tcggaaagtt tagcaattga tattctgact tttttaacag gaatttcaag
     5581 tcgagacggg gagaagtttc ctgtgttacg taaagccatt cgaacggtga ctcaaagtga
     5641 tcaacggggg ttattacaag ttattaacga attgcgaaaa gacgggtcac caatcgcgga
     5701 aaatatcgcc gatcatatcg agtcctttac cgattatgat tttgctcatt tgcttttctc
     5761 agacggctcg attacccaat cgattagttt agataaacag ctaaatatca ttcaagtggc
     5821 ggatttggtt ttaccggatg cagaaacgac ttttgaagaa tataccacca tggaattgct
     5881 tagtgtttcg atgctaatcg tcatttccac ttttgccttg gactttatcc atagtaaccg
     5941 agaaatcttc aaaattgtcg atttggatga ggcttggagt tttcttcaag tggctcaagg
     6001 aaaaacgtta tcgaataagc ttgttcgtgc tggtcgggcc atgaatgctg gggtctattt
     6061 cgtcactcaa aatagcgacg atttattaga tgaacgttta aaaaataata tcgggttgaa
     6121 gtttgctttt cgcagtaccg atattcatga aatcaagaaa accttggaat tctttggttt
     6181 ggatcaggag gatcaaagca atcaaaaacg cctgcgagat ttggaaaacg
//
LOCUS       DAIGSZ010000102         6174 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.106, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000102 DAIGSZ010000000
VERSION     DAIGSZ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.106"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            725..811
                     /locus_tag="NOB31_002659"
     CDS             725..811
                     /locus_tag="NOB31_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HCI0974826.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="NOB31_002660"
     CDS             complement(932..1621)
                     /locus_tag="NOB31_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974827.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="NOB31_002661"
     CDS             complement(1628..1906)
                     /locus_tag="NOB31_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974828.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="NOB31_002662"
     CDS             complement(1866..2780)
                     /locus_tag="NOB31_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCI0974829.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="NOB31_002663"
     CDS             complement(2762..3142)
                     /locus_tag="NOB31_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HCI0974830.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3593..3880)
                     /locus_tag="NOB31_002664"
     CDS             complement(3593..3880)
                     /locus_tag="NOB31_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCI0974831.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3900..4124)
                     /locus_tag="NOB31_002665"
     CDS             complement(3900..4124)
                     /locus_tag="NOB31_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HCI0974832.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4579..4749)
                     /locus_tag="NOB31_002666"
     CDS             complement(4579..4749)
                     /locus_tag="NOB31_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974833.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4764..5297)
                     /locus_tag="NOB31_002667"
     CDS             complement(4764..5297)
                     /locus_tag="NOB31_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCI0974834.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5318..6160)
                     /locus_tag="NOB31_002668"
     CDS             complement(5318..6160)
                     /locus_tag="NOB31_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI0974835.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1634 a         1153 c         1041 g         2346 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccaac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag cttactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgccaaaggg gcgcaagctc ccccttgaat ccccctcccc ccccactctc cacaatacaa
     3361 aaaagactag caaatgctag ccactttttg taaagtttcg cttgtttcac cttcggtgaa
     3421 attgttgcaa atcaataatt aggtagagct acattttttt cgttgttcaa agattcttat
     3481 gccatttact attaataaat ctataaatat gataattttt cggctctata atttatggga
     3541 ctgatgaatc agaattgatt cttcagtccc attttcattt tattccaaag aattaactcc
     3601 aaataccaat agaagcccat cctctatata cttgagattc cttactaaca atttcttgta
     3661 attctattaa agatttaggt aatccaaatt tatgttttaa aatatatctt ccaagaaaac
     3721 tacttaattt catactaact tcaccaacac tttttccctc actgatttct ttagaataaa
     3781 gaaagagctt ttcttttaag tcaggatagt catctatagt tgcttcattg tatactttac
     3841 taattgcatt taaaagtttt tcttctttag taaaatccat tataataacc tccctaccac
     3901 taccttctag gtgcccatgg accatgatta acccaaccat taacaataat ttttccaatt
     3961 tctcctttag cttgattcca atctacccaa catttttctt tgttacaata aagaccattt
     4021 ccatagtaag tagctgcatc aacttttatt cctgtaccga tgccagctag acaagttcct
     4081 aatattccta gaataacaca atgttttaat actttctttt tcatgattgt ttttcctttt
     4141 cgttttttta aaattgcttg ttatattaaa taatcttagt aattttatta tataacattt
     4201 tattatataa caatgattaa cgtcataaaa agtagttttg aattcataat cgtttaaata
     4261 aaattataag atcagttatt taaacagcta gtagacataa tgtcgatact accaagtaac
     4321 gcctgtacca agggatccag gcgctgattt tgtgaatttt tattggtcta ggttaaaagc
     4381 tctttttaag gcttggtttt ctgcggttgt ttctttctaa ttctttgtga atattgatcg
     4441 gtcatttttt aaatacttgt tatttttgtt tgtgtttgtt atgcttttta catatctcat
     4501 attcatttat tattcttttc taaggttaat aataggataa tctctttcag aaagactgct
     4561 cgtacgagca gtcttttctt atttatcaag tttttctaca aatacttcct cattttgact
     4621 gttgtagtaa ttaggattga gttttagttc ccctttttta tttcctttgt tggccactga
     4681 taataacatt gggctaaagc ttaatattcc tagtaggata gaaccgaata gcaagtgttt
     4741 ttttgtcata agtatttcct tcttcatttc catagctgcc accatttttt ccaattcttt
     4801 gtttgttcgt ccattgtttc tgttgcttca gaaagagtcg ttgaactatt ctctgaagac
     4861 tcttccgtat aagtcaactg cagttgctcc tgaagttttt cgatttgttg gttggcttgc
     4921 agggtgagtt gttgttgctg gtcgagtagt ttttgtatat gagaattatt ttgctctttg
     4981 agggcaagtt gttctcgtaa aaattcattt tcttcacgca actgatctag caacttgttt
     5041 gcaaccacgt ttttgtttgg tatataagca tttttatcgt tgttttgttc atgtttatgc
     5101 aacttatcta gcaacctttg attgtctaag ttgcgagcaa gttgcaatac tccagaacgc
     5161 aatacaacct tataaccacg ctcattttta gctatcatgg aagaatctaa tttttggata
     5221 tgtttcgata ttgcttgcct actcatctta aaaagatctg acaattcctt tattgtaaag
     5281 gtttcttgtg gttgcatact ggttgcctcc taggttgcta ctggaataaa ttatctaaat
     5341 cagataataa actttttttc tctttttccg aaagtgcgga ctctgtttgt ttttcaagag
     5401 cttttttctc tttttctagt tgtttgattt gttggaggag ttcaagttct cgtttcttct
     5461 gtttgatttt ttcgttaatt gttgtagcgg gttcttcgta ttctttttgt ttatcagcta
     5521 aagccaatgc tttattttgg tcttctttgg ttggtgcatg tttgttaaag tcgtctgctt
     5581 ttttgatctc aggtttgaac gtaaattgat agccaataac aggttttccc cgtccttttc
     5641 cgtatttctt tttgattgtt agtcctttga agattgcagt tagttcttga cgtataggtt
     5701 ttataactcg tttatctata tcaggttgct tataactttt aggaatatct aataattcaa
     5761 gaaagtcttc tttggagaaa tatgcgaaac ctttggttct gtattgcttt aacagacgaa
     5821 acatagtctt tgcatagcca ctttgtagct cgttgaattg ttgtaaagaa tagcgtaccc
     5881 actcgtctaa attatttaac aaaggcagtg ctttttcgta aattcgtata tctacgtaag
     5941 gattttctac gtccccgttg attttaaatt ctgtaaacat tacaaacata tcgtaagaaa
     6001 gcccagactc acttctacga ccaaagcgta aagataagat tttttcataa gttgctttta
     6061 aatcttctac aaatcgtaca tttgcagttg ctttgtagtt acttaaatct tttagttggt
     6121 caaacgtaaa acgaactgtc ttatcccctt tttcacgcat tctagacacg atgg
//
LOCUS       DAIGSZ010000103         6113 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.107, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000103 DAIGSZ010000000
VERSION     DAIGSZ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6113
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.107"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            56..901
                     /locus_tag="NOB31_002669"
     CDS             56..901
                     /locus_tag="NOB31_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0974836.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1182..2402
                     /locus_tag="NOB31_002670"
     CDS             1182..2402
                     /locus_tag="NOB31_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HCI0974837.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2399..5119
                     /locus_tag="NOB31_002671"
     CDS             2399..5119
                     /locus_tag="NOB31_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0974838.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5103..6047
                     /locus_tag="NOB31_002672"
     CDS             5103..6047
                     /locus_tag="NOB31_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0974839.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2284 a          961 c         1195 g         1673 t
ORIGIN      
        1 gtgagaaatt tagacttaca ataagcagtg aatttataat caacgtatag gagacatgga
       61 tgaaatgaaa ctaattggta tagatttaga cggtactctt ttgaattctg accagagcat
      121 tagtcaaaaa aatgcaagaa caatgaaaca tttaccggaa gactgttttc cattcatttg
      181 ttctggaaga gaagtagaag acattaataa tattctcaaa aaatctggtt taaggatacc
      241 agcagtaggg ttaaatggtt ctgttggatt tgatggagaa aaaaagatat ttgagtcttc
      301 cttcgataaa aatgatgtaa aaaaaattga ttctgtccta tcgaaatttc caaccaaaat
      361 atatacaaat ctcggaagtt atgaatctca gaattataaa aataaaatga aaaaaatttt
      421 tcacgaggta gggagtgaat tttctatcaa agagctaaac tatgagcttg agtatgaaaa
      481 atctatttgt tcaatccctt ataataatat tgaggaaatt atagaaaagg atgctatcag
      541 catttacaaa ttttttattt ttattcctaa tcgtcaattg aaagctaata tatttaacca
      601 tttgaaaaag atgctaaatg tgtctgttac tgaatcggca cctgtaaata ttgaaatcgt
      661 acctcaaaat gtatctaaag gtgtggtgtt tgatcgtttg gaatcaatct acaatttaaa
      721 gaaacctttg agaatcgcga tcggagatag tttaaatgac ttatctatgt ttgaaagtgc
      781 agatattagt tttgcaatgg gaaatagtca tcaagaaatc atgaaaaaag ctgattatgt
      841 cactgtttca aatgataaag acggagtatc tcaagcattt gaaagaattc ttaccatata
      901 aactaattaa ggtagtatag aacatagaat tctaaatacg gaaaaatgga gcataaattc
      961 cagtacaaat agtacttctt cagtgtcaaa cgaagcgaat ataacataga tatttaggat
     1021 tgtgacaaaa atcatgtcac aatctttttt tcgaataaac ttattttttg aagtcggcca
     1081 tttatcgtaa tttctttgca taatacgaac aaattttcgg ttattgatga aaaaaaacat
     1141 tgaaaatggt atgataaaag aaaaaaagga ggaaattttt aatggtgaaa tttatccatg
     1201 cggcagattt acatatggat cggtcatttg aaggactgac aactcttgat aaaactgtac
     1261 aggaaaaact attgaagacg aatctgaccg ttttatcaaa tatcattgaa caggcaataa
     1321 taaataacgt tgattttgtt ttacttgcag gagataattt tcatcaaaat cgtccttcat
     1381 taaaaataca gaaacatttt tcagaacaga tgaaacggtt agaaaagaac catatacctg
     1441 tatttataat attcggaaat catgatttct atcaaaaaga gcggtattgg ttctcctttc
     1501 ctaaaaatgt ccatttattt acatccgaaa cggtagagac aaaaaaaata acgataaaaa
     1561 gtggagaaac tgtctctctc agtggattta gttatcgtca accgtggatt caaaaagaca
     1621 aagtgatgga atttccttct agagaactca cagattacca tattgggttg taccacgggg
     1681 aacctggcgt ctctcaaaaa ggaaactatg ctcctttcca accctcaaag atgcaagaaa
     1741 agggatacga ttattgggct ttagggcata tccatgtgcc aacggtctta aatgaaaagc
     1801 aaacaattgt ttatccaggt gcgcctcaag gtcatactaa aaaggaacaa gcttctacat
     1861 ctattctact agttgaatta agtaaaggaa gttgccaaat acatccgatt aaagtagcag
     1921 aggtctattg gaagacaaag gaaatatcat tgaggaaagc aagaacgaca aaagaggtca
     1981 ttgttcacat tcgtcagcag ctttcaaaag tagaggatgg atttagttta attgagataa
     2041 aattaaaaga ttatgaccat ctcaatacag atgttttgga acggatacaa tcaggagagc
     2101 tattagacta tttgttagag gaattctcag ataggataaa tgatttcttt atttggcgta
     2161 tttctctcat agagaatact ttttatacga agaccccact tgctgcttct gctaaattga
     2221 tggaacagtt atttcaatac tatcagacac ctcaagattt ccaacaaatt ttaaatgaag
     2281 tatatagtca tcaagaagcg gctagaatat tgagcgaact gccggaatat caagaagaaa
     2341 cacttgaaaa agccaagcag ctgcttaatc aagatttttt atttgaggag gatcaggaat
     2401 gaagatttta aggatcgaga ttgctgcttt tggaaaatgg cgtcaaaaaa gttttgactt
     2461 ttattcaggc aatcagctga tctatggggg aaacgaagca ggaaaatcaa cgatttatca
     2521 atttattcaa gcaatattat ttggtttccc ttcaaaaggc cgtaaaaaaa aggattatac
     2581 accaaaagac ggctcagcct atggcggcaa aatatggctt aaacatcctg tatatggtga
     2641 atttgctgtc gagcgctaca agcagcaaaa tcgcggaaaa tcgaaggtgt ggctggggga
     2701 tcaagtggga agtgatgagt tactagaaaa actgatcgca cctttgacga aagagttatt
     2761 ccagcaggta tttactttcc agcaagagca gttgatggaa ctagatcatt tgagagaaaa
     2821 agagctacat gatgcgctga tttctttagg catcacgggc agttctcaag tattccaaaa
     2881 gcggcaagaa tattatcaga aagcacaaca attattcaag aaaaaaggcc aaaaattact
     2941 aatcaatcaa aaattaaatg aatggaaaga gctgcaagaa aaaattcatc aaaaacaaga
     3001 acaggaagct tattttggca agttgatcca acaagaacag gaatacgagt cgcaacagca
     3061 gcagttattg gcacaattaa aagaggcgaa caaacaattt tcattagcca gacagcaaga
     3121 acttaatttt tctttatatg aagaatggca atctctcaaa aaaaacagca ctacaggtct
     3181 tcctgatgag caacttcttt tagatctgga gtctttctcc aaacggtatc agcaaacaaa
     3241 tgagcgtttg gaagaattag aagcaacact ggaaaagcat agcgggatgg atcagcagtc
     3301 agccagatat tatttttatt tagagcagga gcaggaacta aaagatctcc agcaacttca
     3361 atttacagcg gaacaattaa acgaagaatg gcaaagatta caaattgaga ctagagaaac
     3421 aaattcagaa ttgaagattt tggaacaaag gtggcattgg cagaaaaatc cgttaccgga
     3481 agaattttta tatgaagaag aatggaagca tcttctggct gaagaaagaa ggattgctga
     3541 tctagaaagc cagatttctg tgcgtctcca aatagctaaa gaacagcaag agatgattga
     3601 agcagaagtg aatgacttgg aagagaccta tccagcatta ttacaaaatc agtcagagat
     3661 agcaccagtc tcttcatcta aaccgtatat gctgatggct ggcggagcaa taatcattgc
     3721 aggtatattt gtaccaatgc ccttgaaagt gatcctttta ctaattggtg caggcatgat
     3781 tggctatttc ttctacaaaa ggcaaccaaa aattaaaact aaaaatgatt tctctgagat
     3841 aaaaggaatg tggcaagaaa aactaggaca acttgatcta gccttagctc aattagctga
     3901 agcagaagaa aaacaaaaga gaactggaga agaaaaacag attcttcagc aagaagtata
     3961 tcgttttgcg gatcatcggc acttaggaaa gatggatacg ctcaaactca tgaaagaata
     4021 tggacaggaa gtcatagatt atcagaaatt atatggcgta tttgagcgga aacataaaag
     4081 agaacaggaa atacaagaaa aactacgaca aatcgaccaa aaatttgagt ttgttaaaga
     4141 atggttaccg atacaagata agacaatttc agaaaaaatg gtattgcttt cccgttttat
     4201 acaagagatg gaacagatga aatttgccag aagctatcag caaaatactt tattgaagca
     4261 agaaatcaat caattgaaaa agaaacaaaa agtatggata caagaataca gcgaacaatt
     4321 gactcaagca ggcttatctt atccttcgga agtacctgtc tttttacaaa aagccaaaca
     4381 agccgaacag cagatgaaaa gatacaatga attatcggaa atgcttactc cactatttcc
     4441 tgaagagctg acaaaagaga aattatctgt aagactgcgc caactgaaag aaaagcaatc
     4501 ccaactccag caagaagaaa aagaagcaag tgaaaatcgg caacgactcc aacttcaagt
     4561 agaagagttg caaagagacg gcacattgga cgaactttat caacaagcta gccggcaaaa
     4621 agcaaaatta caggaattac tggaggaatg gggagcactt gaaatcgccg ggacattctt
     4681 aggtgatctt tcaacagaga tgagtgaaag acaattaccc cagttgttaa gagcagcagg
     4741 tgattattta ggtattttaa caaaaggaaa ttatcagaag atattactga aaaatgatac
     4801 actgacttta acagacggat atacagaatt tcccatctat gagttatcta caggtacgaa
     4861 agatcagctg attatggcga tgagatttgc ttacctctca ttagaagcta accgttcgat
     4921 atgcccgatc atcattgatg atggctggct tcattatgat catcagcgaa agtatcaatt
     4981 agctgaactt ttagctaaat ttggagaaaa gtatcaaata atttgttttt cttctgataa
     5041 agaaatggta agctattacc atgagatgaa ccaaatcgta aaacaattag aaggagcaaa
     5101 taatgaaaaa aattcgtgat ttagtaatcg atgagcagtt tgaacaattt gtcctgatca
     5161 aaagtgcaga tgtaagaatc gctaaaaacg gaaaaaaatt tattgctttt actttccaag
     5221 atacttcagg tactatcgat ggtaaatact gggatgcttc ggaggaggaa atcaataaat
     5281 ttacagccgg cacagtcgtt tttctaaacg gtaaaagaga ggtttatcaa ggaaaccctc
     5341 aagtaaagat tcttcatatg cgcttaacaa gggtagatga gccaggagag cctagtttat
     5401 acatggaaag agcccctttg aagaaagaag aaatggaaga agaaatcaat caattgttgt
     5461 ttgagatcac caatgcgcat tggaatcgta ttgttcgcta tctacttaat aaatatcaaa
     5521 aacaattttt tgagtttccg gcagcaaaaa gaaaccatca tgcatttgcc agtggattag
     5581 cttatcatac tttgacaatg cttcacttag ggaaatcaat cgccgatgaa tatcctgagc
     5641 tgaatcgagc attgttgtat gctggtatca ttttgcatga tttaggaaag gtgattgaac
     5701 tttccggtcc tatgtcgaca gaatatacgc ttgcaggaaa tttgatcggt catctggtat
     5761 tgattgacga agaaataact aaagcctgtc ttgcgttgaa aatcagcgaa gctgacgaag
     5821 atgttctcgt attacgtcat atggttttag cacaccatgg cttattagaa tatggctcac
     5881 ctgtacgtcc aagaataatg gaagcagaaa tattacatca aatcgacaat atcgatgctt
     5941 cgatgcagat gatgttgact tcgattcgtc aaacagaacc aggaaaatac accgatcgga
     6001 ttttcggtat ggacaaccga agtttctatg taccaaaaga tttatagcaa aaatttattt
     6061 ttttcattca aaacaaaaaa agcgagacat aagtcttcgc tttttttgtt ttc
//
LOCUS       DAIGSZ010000104         6096 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.108, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000104 DAIGSZ010000000
VERSION     DAIGSZ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.108"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..474
                     /locus_tag="NOB31_002673"
     CDS             <1..474
                     /locus_tag="NOB31_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HCI0974840.1"
                     /translation="INSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLE
                     PEEYLTILKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEI
                     ETALNKIQDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            447..1124
                     /locus_tag="NOB31_002674"
     CDS             447..1124
                     /locus_tag="NOB31_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HCI0974841.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            1114..2256
                     /locus_tag="NOB31_002675"
     CDS             1114..2256
                     /locus_tag="NOB31_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HCI0974842.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            2269..3246
                     /locus_tag="NOB31_002676"
     CDS             2269..3246
                     /locus_tag="NOB31_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCI0974843.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            3246..4154
                     /locus_tag="NOB31_002677"
     CDS             3246..4154
                     /locus_tag="NOB31_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HCI0974844.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            4155..4907
                     /locus_tag="NOB31_002678"
     CDS             4155..4907
                     /locus_tag="NOB31_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HCI0974845.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            4912..5859
                     /locus_tag="NOB31_002679"
     CDS             4912..5859
                     /locus_tag="NOB31_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HCI0974846.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYNKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         2232 a          767 c         1160 g         1937 t
ORIGIN      
        1 atcaattcaa tggaacaaca atctcaacca attatttgca ttttacctaa tagtgatgct
       61 ggtagcgaaa ttatcagaaa aatgtaccag aaatatttaa aaacggatat tatttatatt
      121 acgaatttag agccggagga atacctgact atattaaaag agtgcaaatt tatgatcgga
      181 aattcttctt ctgggataat tgaagctgca tcattcaaaa taccagtaat aaatttagga
      241 accagacaaa atggacgaga acaatctaaa aatattataa atgcaaatct aaatgaaaat
      301 gaaattgaaa ctgctttgaa taaaatacaa gatcctcagt ttataaaaag cttgaaaaat
      361 gttaagaaca tctacggtga cggcaacagt tctagaagaa taacaaaaac attgaatcaa
      421 atattgaatg atggggaaga tattaagtgg attcaaaaac aaatagctta ttaaaatata
      481 ctagtgatcc atacattatt attggggctg gcggacacgc aaaagtcatt attgaaacct
      541 taagattaga aaataagtta atatatggat tttttgatga taagcaaaat aaaatgcaag
      601 atctgaaata tcttgggaaa ataaacgaat tgaatagctg ggcggatagc aaaaaaaaaa
      661 tctataaatt tattgtagct attggtgact gtgtagtaag aaaaaagatt ataaaaaaat
      721 tgaatatgcc aagtgagcaa tatggaatag ctgttcatcc aagtgctata gtggcaaaag
      781 aaatttcaat tggttatgga actgttattt ttgcgaatgc tgtaattaac ccagatgctg
      841 taattggaga gcatgctata ataaacacag gtagcattgt tgagcatgat tgtagaatta
      901 ataactatgt tcatttatct ccaggtgtat gcttagcggg tggagtacat gtaggtgtag
      961 gaactcaaat aggaattggt tctcaatgta tccagatgaa gaaaattgga tcttggtgta
     1021 tgataggcgc agggagcact attgttaagg atattccctc acattcctta gcttatggca
     1081 atccagctaa aattaagaaa gaaggaatta attttgaatt ctagaatttt attatcaagt
     1141 cctcatatgg gaggaacaga agaaaaatat gttgctaagg cttttaaaga taattggata
     1201 gcgccattag gtgaaaatgt ggataaattt gaagaaagta ttacaaaata tactggttct
     1261 aagggcggag cttctgcgtt aagttcaggt acagctgcca tacatcttgc cttaagactg
     1321 cttaatgttg gaaaaaacga tattgtcttt gctccttcat ttacttttat agctacagta
     1381 aatcctattt tatatcaagg ggctgtacca gtgttcattg actcagaacc taatacatgg
     1441 aatatgagcc ctgttgcact agagagcgca ttagaagaag ctgaaagaaa caaccaatta
     1501 cctaaggcaa tcatcgtagt gaatttatat ggtcaaatgg ctgattatga acgaatttta
     1561 gctattgcaa accaatttaa tgttccagtg atagaagatg cagcggaatc gttaggttct
     1621 acttataagg gaatttcgtc aggcttattt gggacaattg ggatctattc atttaacggt
     1681 aataagatca tcacaacctc aggtggagga gctctagtgt ctagtgataa aaaatatgtt
     1741 gagcattcaa gatttttagc aacacaagca agagatcaag caccgtatta tcaacatagc
     1801 gaaataggtt ataattaccg tctaagcaat atttctgccg gtatcggacg tggacaaatg
     1861 gaagtattga atgatagagt agctaaacga agagaaattt tcaatcgata taaggaagct
     1921 ttttctggaa ttgatagaat tgaaatgatg ccagaagtgg atggcatggt gccaaatcgt
     1981 tggttgtcta ctttaacgat caatgattat aattctattg atcaagtagt taacgtaata
     2041 aataaactaa atgaaaaaaa cattgaaaca agagctttgt ggaaaccact acatttgcaa
     2101 ccagtatttc aaggggtaaa aatgtattac catgataata atcttagtgt gtcagaaaag
     2161 ttatttaata gcggcttatg cttaccttct ggaagtaata tgacagatag tgaacaagaa
     2221 tttgttattg atgagtttaa aaaaatattc aagtaggtgt gatattttat gaacatagga
     2281 attattggtt taggttccat ggggaaaaga agacttagac tcattcaaga acactttaat
     2341 gatattttac tatgtggtgt tgatactaat gaggcgagac gaaaggaagt tgaaaaggaa
     2401 tttggaatac caacttataa tagtctaaca gaggcaaaaa atttgtttga aataaattca
     2461 gtttttgttt gtacatcccc tataacccat gaatttatta taaaagaggc tttaaattta
     2521 gattgtaata tctttacgga aatcaattta ttaaatgaat attatgatga aataatcgaa
     2581 gtagctaaaa agaaagatag attactttat ctatcttcta catttttgaa gagaaaagaa
     2641 attcaatata ttaagtctaa agtgacgcat aataaaaaaa tttcttatca ataccatgta
     2701 ggacagtatt tacccgactg gcatccttgg gaagattatc gcaatttttt tgtttcaaac
     2761 aaaaaaacta atgggtgtag agaaatattc gctattgaat taccttggat tatagataca
     2821 tttgggaaag ttaaatcgtt tactgtaatg acccagaaat tatccaatct tgatattgat
     2881 tattcggaca gtttcactct tattattgag catgaaactg gtatagttgg aactttaagt
     2941 gtagatgttg tttcaagagt agctaaaaga aatttaacta taattggtga aaagatttta
     3001 atagaatggg aaggtaaccc ggattctcta ttttcatgga atgaagaaac ttctagtatg
     3061 acagatattc aattgtacga tgaggttatg catgataata attattcaca tactattatt
     3121 gaagatgcat atttagagga gattaaagaa tttttcacgc ttttggaaaa gaaaatggaa
     3181 ccccaatata cttttgaaaa agataagtat attattaact taattaacga cattgaggta
     3241 aattaatgat gaaagtaatt ttttttgggt tagggtcaat tggaaagaga catctaaaaa
     3301 atctaataag ctatggaaaa aagaattcta ttaattttga tataacagct tatagtagca
     3361 gtggaaaaaa agagtttgaa gaaataacgt atattcaaaa tagagacgat ttggatacac
     3421 attatgatat agcttttatt acaaatccga cttttaagca tctggaaaca ctaaatgtaa
     3481 ttgttgaaaa agttgattac atatttttag aaaaacctgc tttttctgag agtattgatc
     3541 ttactcaata taattatgat tacaaaaata tttatgttgc tgctccactg aggtataaaa
     3601 atatcatgga agttgttcgt aatagtattc aaagtaaaaa agtatattct gtaagagcta
     3661 tttgttctac ttatcttcct gattggagaa aaggtactga ttatagaaat aattattctg
     3721 cctttaaatc tatgggggga ggagtagaat tagactgtat acatgaattg gattatatta
     3781 taaacctatt tggtttccct aaatcagtaa aaaaacagtt tggtaaatat tcgaatcttg
     3841 aaattaacag taatgattta gcaacatata tattgagata cgatgataaa attatagaaa
     3901 ttcatttaga ttattttgga agagttccta caagaaaatt tcaattgttt actttagatg
     3961 aatgtatcaa tgttgactta ttaaataata aaataagttt tgaagaaaac attgttaaag
     4021 aaatgcctga atctgctaat gatatgtatg agaaggagtt gaaatatttc tttgaaaacg
     4081 tagtaacagg caaagaaaac tggaatgatt tatatcatgc aaacgaagta ttgaaaatag
     4141 ctgaggagaa ataaatggaa attttattta ctatttgtgg tagagctggg tctaaggggt
     4201 ttaaaaataa aaatttgaaa tatttggcag gaaagcccct agtccatttc gctttagcaa
     4261 tgatagatat ctatcaacaa aaacatcctg aacataattg cacgacttgt ttgaatacgg
     4321 acagtaatga gttagtagaa ttgacgacta agttaaatcc gtctgtgaaa attgtagaac
     4381 gtaaacctga attagctaca gatactgtag ggaaaattga agtgatacgt gattcattct
     4441 tacaactaga aagagaagat aatatatttg atttaattat agatttagat ttgacttcac
     4501 ctttacgtga agtttctaat cttgaagaat taatagatga acatctaaaa aatttagata
     4561 aagacgtcta cttttcagtt gtttctgcaa gacgtaatcc ctattttaat atggtaaaaa
     4621 gaattgaaaa tgaagttact atagttaata aatcaagata cacatctagg caacagacac
     4681 ctgaagtttt tgaaatgaat gcctcaatgt attcttttaa acctgaattt ctaaaaaaaa
     4741 gtaattatat ttttgatggg caatgtggga taataaaaat gagagattat ctaattttag
     4801 atattgatag tgaagaagat tttaaatggt tagaattttt gtttcctaaa tttttagaag
     4861 attcttcgga gcttcaagat atctataatt atttatatcg gaggtaaaag gatgagctgt
     4921 tatcttatca ccggtggggc tggcttcatt ggttctacct tagccaatca tttaggagaa
     4981 gaacatgtgg taatcgtcgt cgatgactta tcaatgggaa aagtagaaaa tcttgatatg
     5041 acgaaaaata tcacttttat tgagggagat gtcgctgaga aatccttgat ggaagagatc
     5101 atgaaagcta ataaatttga ttatatcttt catttagcag cagttgctag tgtggcagat
     5161 tcagttgccc gaccagtaga aacacatcgt gtgaattttg aaagtgtatt aatgatttta
     5221 gaattgatcc gcaagtatca acctgattta aaacggatcg tgtttagttc ttcagcggct
     5281 gtttatgggg atgaaccgac tttaccaaaa aaagaagagt ccgtgattcg cccattgacg
     5341 ccttatgcgg ttgataaatt cgctgcagaa caatatgtgc tagattattg tcatttatat
     5401 gatgtacccg gtagcgcagt tcgttttttc aatgtctatg gtccaaatca aaatccgaat
     5461 tctccataca gtggtgtgat ttctattctc gtagatcgct ataataaaca aatcgtagga
     5521 gaagcaactt catttacatt atttggtgat ggaagccagt ctagagactt tgtttatata
     5581 gatgatgtaa tccaagcatt acttttagtt gcgaatgagg aagctgcact ggggaaacaa
     5641 ttcaatgttg gaacgggtaa agcaaccaca cttttggaat tgattcatgc aatcaatgaa
     5701 attctcggtg tagaattgac acttgaatac aaagaagagc gttcgggtga tatccatgac
     5761 tctctagcag atattactaa gatccagtca attggctatc aaccgaaata tggtatttta
     5821 agtggaatga ctaattattt gaaaactgaa atcaattaaa acatactaag ataagattag
     5881 agggtaaatt caggctcttt gtcaataagg actgatgagt tttgtaaaat caaatctggg
     5941 atagaagggc tctttgtcaa atgatgttgg taaagagaaa tcttagaata atttggacag
     6001 aacagaaaga agaaaacctc tttctgttct gtttatttgg ttaaaaatgt tttgccatga
     6061 cgaatcataa ttcgtagttt gaaattgtaa aagttg
//
LOCUS       DAIGSZ010000105         6021 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.109, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000105 DAIGSZ010000000
VERSION     DAIGSZ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.109"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(60..362)
                     /locus_tag="NOB31_002680"
     CDS             complement(60..362)
                     /locus_tag="NOB31_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974847.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(582..948)
                     /gene="ssrA"
                     /locus_tag="NOB31_002681"
     tmRNA           complement(582..948)
                     /gene="ssrA"
                     /locus_tag="NOB31_002681"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1119..1892)
                     /locus_tag="NOB31_002682"
     CDS             complement(1119..1892)
                     /locus_tag="NOB31_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCI0974848.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2036..2386
                     /locus_tag="NOB31_002683"
     CDS             2036..2386
                     /locus_tag="NOB31_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCI0974849.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2367..3083
                     /locus_tag="NOB31_002684"
     CDS             2367..3083
                     /locus_tag="NOB31_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0974850.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3083..4531
                     /locus_tag="NOB31_002685"
     CDS             3083..4531
                     /locus_tag="NOB31_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0974851.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4602..5111)
                     /locus_tag="NOB31_002686"
     CDS             complement(4602..5111)
                     /locus_tag="NOB31_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974852.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5101..5826)
                     /locus_tag="NOB31_002687"
     CDS             complement(5101..5826)
                     /locus_tag="NOB31_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974853.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         2046 a         1050 c         1170 g         1755 t
ORIGIN      
        1 cccttttata agtatggtga taaaatccgt tccgggctac cttttttagg tagcctactt
       61 taatctttat acctttctgg atcaacgaaa gtatacttca aatagtcata acgccgatga
      121 tcgctccgtg cgtctggcac atcagtcacg atatcaaaca aaaaatacac atctttcttc
      181 attctggttt ttgttgccgg aattttaaag tagttcttat tagagtaata gagattgatt
      241 aataagctat cttcgattgc taaaaagaaa acttctgaat cccacacctt ataaaaatct
      301 ttgacaaatc tattcgaagg atcaaattta aaccataatt gtgtttttcc ttccatcaac
      361 ataatgttca cctcaaaaag agtatacgaa ctaatgttct ttttgtaaag taggaatatc
      421 attgataata tggatggaac atatatatta aaaagtgttc tttttgaatg ctattttgaa
      481 tgccattttc attcatttaa cgaaaatctg cgaaaataaa aaatgctcaa acccttataa
      541 aataaggatt taagcatcta gcgaaatctg ctgaaatctc acaatggaga cggcgggagt
      601 cgaacccgcg tccaaacaca tcgccactta aaaatctacg ttcatagtca actcatttaa
      661 ggattcactt tacagcttgc cgagtgacag gcattctgta tcgctagtct gatgttctct
      721 ttttcaactt acagacggaa agttgaaacg tatcccacta aagttaggac ccttactcga
      781 gcacatgggc gatgccgaga ggatctacgc taactgtttt taggcagcta aagcgtaaga
      841 gttgttttcg tttttagcag ttatatttaa ctgtaacgtt tttacgtaga cgtaacctac
      901 gaaacgcaat tcaagctcga ctgtgcctgt cgaatccgta acgtccccgt tagctaacaa
      961 gggttacgtg tatttttcat acaaaattag tatagcatat attgggataa attcaataaa
     1021 aaagcgaatc atatcccatt atttatataa taactgcccc tttcttaaga aaaaataagc
     1081 gattttctta agaaaagagg tagcttcaaa aaaagatctt aaatcagatc aaaatacttc
     1141 aatgcgtgga caattccgcc ttctgtattt ttctttgtga taaaggtaga aagttctttt
     1201 aatccgtcat aggcgttgcc catagcgatt ttgttgtcgc aagcttccaa caaggcaaaa
     1261 tcattcggac catcgccaaa tccaaaagta ggaacttttt ccagctgaag ttctttttgc
     1321 agacgtttga cacctgcccc ttttgagatt cctttcttca ctgtatcgat cgagtaagga
     1381 ccattccgat aaaaagttag ctcaggaaaa tgttcgtgat agtattcgtc acctgattga
     1441 gataagatca gcaacatatt tactgtgttt tctttaaagc ctaaaggatc aatttccgga
     1501 acatctgaat gaatgaagtc gtaagcattg atcattgttt ggctatgacc ggtacaccag
     1561 attttctgat cgttatagta agaaagttca tgaccgttca actgtacatg atcatacatt
     1621 ttttgacatt cttctgaaga aaatgtttga gaatagattt cttcgccgtc tactcgaatg
     1681 aaagaaccat tcatggtgac cgcagaagta atgcccgcat cttccatgat agagtggatt
     1741 tctgcttctg tacgtcctgt agcgatgacg gggagaacat tgttttcttt taatgcgttc
     1801 atagcttttg ccacttcggg tgtgattttt gatttcgcat ctagtaatgt tccatcaaga
     1861 tcaaagaaag tgattgcacg ataatttgac acaaataaaa ctcctttttt attggaataa
     1921 gtttatctta acaaagaatg aacaaaagac aaacctttcg tgaagaattc ctgaacatat
     1981 tggttcagtc aacaatttag agtatactat aagaagagaa tttaggaggg aaagaatgat
     2041 ttttttcagt attggtatct tattcttaat aattggcagt ctttttcgga ttctgccctc
     2101 aaaaggaaat ctgccttttt atgggtatca ttcgcctctt gccgcaaaaa cagacgctca
     2161 ttggcggctg gctcaaaaga caagcggaaa ctggtttttt cttatgggct tactgatggc
     2221 attgatcggc tattatttaa agacatctgg gcatacgaat tattttctga ttgaaatgct
     2281 tctgctagta tttccaatta tgcctatttt tattatgaca gaaaagaaat tacagaaata
     2341 tgacctggaa actggaggga acgataatga atattttaat gattgaagat aatcaatctg
     2401 tttctgaaat gatgcagatg tttttcttaa atgaaggttg ggaagcaact ttcaagtatg
     2461 atggaaaaga agggctcgat gcctttttag aaaacccaca acattgggat atgattacac
     2521 tagacctgaa tttgcccaca ctggacggta tgctagtagg aagagagatc cgcaaagttt
     2581 caagtactgt gccgattatc atgctgacag ctagagattc tgaaagcgat caggtgatcg
     2641 gcttagagat gggggcagat gattatgtca caaaaccttt cagtcctctg acgcttattg
     2701 ctcgaatgaa agctttgcat cgccgtagtg agttggcaga agcaagagaa gaagcagtag
     2761 tttcagatga tcattttgat atcgagacta gtcatttcaa gatgaatacg aaaacacgag
     2821 aagcgtatct ggacaaccgg ccaattgaag gactgacgcc taaagagttc gatctattgt
     2881 ttactttagc aaaaaaacca cgtcaagtat tctctcggga gcagttgctt gaattagtct
     2941 gggattatca gtactttggt gatgaacgga cagtggacgc ccatatcaag aaattacgac
     3001 aaaaaatcga aaaggtcgga ccacaagtca tccaaactgt ttggggagtc ggctacaaat
     3061 tcgatgattc tggtgttgcc taatgcgtta tttgtatcag caactcttag ctttctgcgg
     3121 aatggtcgcg ttgatcttat tgatcgttgg agtttctttt acacaactga caaaacaaac
     3181 gattgaagaa aacaattacc agcaactgtt tggatatgct gaatcagttg aaaagacaac
     3241 gcaaacctat gccgatacgc tcccgcagtt tagtcaagat caggcgtttc aaaatgcatt
     3301 gctgctgaca gagcaagtac tgacagaaca aaatgtgaac tttatattta tcgataaaaa
     3361 cgaacgtgtc atttatccga ctaatacagc tttactgaat tttaccttaa cagctgatca
     3421 atggaaaaat ctgaggaatg gacgtcaaga aaaattcaca tcgaataaaa atattttagg
     3481 acaagcacag gcgacctctt acgcacttgt gccatttaat ttgaatcatg aattctatgg
     3541 agcacttgta gttagtcaac ctgcgcgaaa tatcgataac agcgttcgtc caattacact
     3601 gaacctgttc aaaggattta ttttttccag tatcgttgca gttattgcca gctatgcttt
     3661 tgcagcattc caagttaagc gtatcaatcg gttaaggaat gcgacgaaag aagtgacgaa
     3721 tggtaatttt gatgtacagc tccccgtaca tgacaaagat gaatttgatg agttagcaga
     3781 tgatttcaat aaaatgacga attcattgaa agaatctcaa gcagaaattg aagaacaaga
     3841 aaatcgtcga agacaattta tggcagatgc ttctcacgag atgagaacac ctcttacgac
     3901 aatcaacgga cttctggaag ggttagaata caatgcaatc cctgaaaatc agcgagaaaa
     3961 cgcgattaaa ttgatgaaaa atgaaacaga gcgtctgatc cgtttggtga atgaaaactt
     4021 ggattatgaa aaaatccgta cgaatcaaat cagtatggtc attaaaaaat tcaatggaac
     4081 agaaacattg aaaaatattg ttgcacagtt agaagctaaa gcagaagcag caggagatac
     4141 attgacattg aaagccgttg atgatattga tgtttacgct gattatgacc gatttgtcca
     4201 aatcatggtc aatattattc aaaacgcgat acagtttact gaaaacggcc aaatcacgat
     4261 tactttagaa aaaggctatc ttgaaacgat catcacgatt gaagatacgg gaattggaat
     4321 gtctgaacaa caaatgaaaa gtatctggga tcgttattat aaagtagatc cttcaagaaa
     4381 aaatacaaaa tatggtgaat caggattagg tttaccaatc gtgcagcaac ttgtacgctt
     4441 gcataaagga aaattagaag tagaaagcga actaggaaaa ggaacaaaat tcgctgttcg
     4501 tttgcctgac gtagaaatca aaaaagagta aaaaacaagc ggtataaaag atcatgaatc
     4561 gatcttctat accgcttgtt ttttactata aaatgattga tttagcccgc gggctctaaa
     4621 cgatcaatat aaggactttg agcaatagta gcatcatgag taaagagtaa gataccttga
     4681 ttttcttcat gagctaaata agaaagcaag tggagtagct cttggatctc caatacacta
     4741 agttcatcaa atgtatcttc aataacaata ttgtttcgct tggaaagcaa ggcatgaagt
     4801 aattgcagct ttactttttc aaaagacgtc aactcagctg ccgcacaatt aagcaaggaa
     4861 ggagagatat caagtttttc ttgataggcc aaacgatctt gtttgatttc tttttccggt
     4921 acatccaaca ggacatggtc tttaagattc agataaggaa acatcggcca atttttttgg
     4981 atgatcgcaa aattatccag ttttgcaaca agaacctctt ttttcaagtg ctccaatatt
     5041 ttatgctgtt tttcgagagg acacaaaata acggtcaagt gttcagcatg aatcaaatat
     5101 tcaggtttca ttacgtccag gcctcctact ttgcaaatga tggataaaaa aagtgaaagg
     5161 gaatagacta agaatgagac agcatccact gagcccaata agagtttggg caaatccctt
     5221 aagtatatct gtgaaaaaaa gatcattttg gaaatcgatg gtaaaaaaag tctgttgatc
     5281 catcggaatt gtaagtccgc ttaccgaagt caagatatca cggatatctg gcagttcagt
     5341 agtctttaag acaagaaaat tgatcctttg aagaagcgct tcataaactg actggaagct
     5401 tacgatccac aataaaacca agatacaaca aagaaagaga ggaaagaaca gctgccagaa
     5461 aataaaaagg aataatttgg ttttagaaag accagtcagg tgccaattga tcaattcctg
     5521 cttgttttgc ctgactgaat agtaaaagaa aaagataaaa aggaaggcaa atagaaaaaa
     5581 taaactgaat atgcctttta tataaaatcg gctagctaat tctaaagccg gaagaagctc
     5641 tgtagatgca gaagcgccaa taaatgaaag ccgatcttgg acttgattgg ctaaagccga
     5701 ttgcaaatgg taaagagtca ggcatgctat caataaaaaa gcagaaaagc ttgaaaataa
     5761 acaatagagt attgtctgct ttttgtaata aattaatcga gcagtagcat agcggattat
     5821 tttcatactt ttcacctcta taaaaagtat agaaaatgaa tatgaataaa gtatgaaatt
     5881 cctttagtga aatcacgaat taaaaccaga aaatattttg taaaaagcaa gaggttgtga
     5941 agaagctgcc ctattctatt accgtagatg caagcttttg aacactgttt attcgaaaag
     6001 aggagcagcg acaataattt t
//
LOCUS       DAIGSZ010000106         5941 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.110, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000106 DAIGSZ010000000
VERSION     DAIGSZ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5941
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.110"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..813
                     /locus_tag="NOB31_002688"
     CDS             <1..813
                     /locus_tag="NOB31_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HCI0974854.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="NOB31_002689"
     CDS             807..1229
                     /locus_tag="NOB31_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974855.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2402..3370
                     /locus_tag="NOB31_002690"
     CDS             2402..3370
                     /locus_tag="NOB31_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI0974856.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKADIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIQKRYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            3387..3911
                     /locus_tag="NOB31_002691"
     CDS             3387..3911
                     /locus_tag="NOB31_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCI0974857.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKTEKKWWQFWQ"
     gene            4287..4568
                     /locus_tag="NOB31_002692"
     CDS             4287..4568
                     /locus_tag="NOB31_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974858.1"
                     /translation="MDILVRNIDPKVISEIDRRCQELTTKTGKKWSRNAYLKVLIEND
                     FDQALRHYKKDQFDLLLEKFIDIQAKNTETLNDYVHTNNQLIETLIGGI"
     gene            4570..4986
                     /locus_tag="NOB31_002693"
     CDS             4570..4986
                     /locus_tag="NOB31_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974859.1"
                     /translation="MRKTSVQKHVTLYPSHIDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPNTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSRNFDPTNFLKR"
     gene            5600..>5941
                     /locus_tag="NOB31_002694"
     CDS             5600..>5941
                     /locus_tag="NOB31_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HCI0974860.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2222 a         1023 c          973 g         1723 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcctttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tctctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgtgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaagtagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaacc cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctctaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcgattat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaagc
     1441 cctttagtga gttttgtaga aagtaccttt aaaggtactt tcacattacg aacgatacgt
     1501 ccgtaagacg tactgaaagg gtgggactta tgagcgaact aatgcaaaat ttggctagca
     1561 aaaaaagtta aaaaatatat gctaataatc gagcgaaatg aacacttttt caagtgagcg
     1621 aatccgccat gacaaagctg aagcagttta tttcagcttt gtcatggcgt gtgcctagac
     1681 ttttaaaaaa gtcggcacac gagcaaatat ctttatcaag ctctaatttg cgttttaaga
     1741 cgtttcaaac gtctaagtat ataaatatat aagaataggt ttaagagtgc ttaaatcgaa
     1801 ttttagaggg cattcagaca attttagggt tgttagggct tgccctgacc gcctgtaagg
     1861 cgctttaaga acaagataag ggatttatac taagactgtc ttaaaacgtc tcaaacgaag
     1921 gctcatagct tctcaaagag ttccttatga acagttttag caaaggagcc ggaggcgact
     1981 gcgcagtata atgtgagagc agagcgatca caccttttta agcgactgta gggagtaaga
     2041 ttcccagttt agaaaaatgc gcgaatctgt ttggagaaaa aagaagtggt tttttaggcg
     2101 ggaaattttg tcccccctct tttataatct ctttttaaac ctctttttaa acctctttac
     2161 cgtcggctgt atccttactc tcccaaggga atgacgcttt tatctacatc gttttgtctg
     2221 tttatctaca tcgttttgtc tgtttatcta catcgttttg tctgtttatc tacatcgttt
     2281 tgtctgtttg tacattgaat tagtacatcg acgatgttaa tataagatgt agataaacag
     2341 acattttgta tttcataacg tctgtatctc ttgtgcgagt aagaaaggag ctattttaaa
     2401 tatgtctaat gaaatcgtaa agtatcatca tgaattaaat acaattccgt tgcgaaaatt
     2461 tacaccagtc gaaatgaatt tgttcttctc tatcgtatca agaatgcgtg atgtaggtga
     2521 taaaaaagta caatttacat tcgagcaatt aaaagattta agcaattata aagcaactgc
     2581 aaatgttcga ttcatagatg atttagaaac aacgtatgac aaattaatgg atttacgttt
     2641 tggtagaaga agtgctgacg gtttgcaacg tgaacgtttt gttttattta atcaatttaa
     2701 aatcgacgga aaagctgata ttccttttgc tgaaatacaa gttcatgaaa aagccttacc
     2761 cttacttaat aatcttgaag aatgggtgcg ctattctctc caacaattca atgaattaga
     2821 aagcagttat tcaaaaacaa tgtttcgatt actaaaacaa tacagaacca aaggtttcgc
     2881 ttatttttca aaagaagact ttcatgaatt acttgatatt cctaaaagtt acaaccaagg
     2941 tacgatcgat caacgtgtgt tcaatccaat acgccaagaa ctaaccgcaa tcttcaaagg
     3001 tctgacaatc caaaagagat acggaaaagg acggggaaag cctgtcattg gctatcaatt
     3061 tacatttaaa cctgagataa aaaaatcaga cgactttaac aaacatgccc caacaaaaga
     3121 agaacaaaac aaagcattag aactagctaa ccaacaagtt caatctgaaa aagcacctac
     3181 ttcattacaa gaaaaaatca aagaacaaaa gcgaaaattg gaacttttac aacagttaga
     3241 aaagttagaa agagaacaaa atacccaaaa taaagaaaat aatgcacaaa aatcagagat
     3301 aaattccgat attccttcag aactaaaaaa agacttatta gacaatcttc aaaacttatt
     3361 caaagattga ggggttttta gattttatga cagaaaaaac aatcaaagaa cttgctgaag
     3421 aattaggagt tagtaaaaca gcaattaaca aaaaagtttc tgacgaaaat cgaaaacttt
     3481 ggttttcgaa aatcggaaac aagtttgtga ttaatgaaac cggacaaaag gctataaaat
     3541 caatgttttt taacgaaaac gaaaactcaa atcaacaact agttggcgaa aaaactaaaa
     3601 ccgaaaacca caaaaacgcc aaccaagttc ccgaattaga agtcctttct ctcctagaac
     3661 aacagttaaa tcaaaaagat atgcaactac aagaaaaaga cgagcaaata aaacaaatgc
     3721 aaaaattact cgaccaacaa caacaactca ccctgcaagc caaccaacaa atcgagaaac
     3781 tgcaggaaca actacagttg acttatacgg aagaatcttc ggaaaataaa tcaacgactc
     3841 tttctgaaga aacagaatcg atagaaaaac aatcaaagac ggagaaaaaa tggtggcaat
     3901 tctggcaata aaaccagcaa tttaaattaa taaaaattgc tggttttatt cttctttttt
     3961 cttttgcgag cagagcaaca tgggcccatg ttgcgatatt ttggtggcgc cccaatcccc
     4021 gttttttcgt tgaatcttac tcggactgca ctcgttttac agctgatttt tctgaatttt
     4081 gaaagagcat aaggaaacgc ggtatcactt tcttacgaaa ggtgctaggt aggctgtgcc
     4141 taccacgttt ctaagaaaaa aatttgctat cactttttcg tcattgtgga tagcttatgt
     4201 atagtgtttc ggcaaaaaac agctatacaa atactatatt tgtatgatat acataaatta
     4261 tacacaaatg cgaaaggaat tcttctatgg acattttagt tcggaatatt gatccaaaag
     4321 ttatttcaga aatagataga cgttgccaag aactcacaac aaaaactggc aaaaaatgga
     4381 gccgtaatgc gtacctaaaa gttctaatcg aaaacgattt tgaccaggca cttaggcatt
     4441 acaaaaaaga tcaattcgat ttattactcg aaaaatttat cgatatacaa gcaaaaaata
     4501 ctgaaacatt gaacgactat gttcatacaa acaaccaact cattgaaaca cttatcggag
     4561 gaatataaca tgagaaaaac ttctgttcaa aaacacgtta ccctttatcc cagtcacatt
     4621 gacgttttag attccatcat cgaaaaaaat ccagatatca ataactactc ggaagccatt
     4681 cgttttctat gtatgagtta tgaacctaat actaatacga caactaccag caaccaagca
     4741 aaactaaatg cgatgggaaa agaaatttct attatgtccg aaatcattgc agaatttgct
     4801 gatttatatc taaaagatac tggtgttctt atcggtacaa attctaaagt atatcaagaa
     4861 gtgaaagaaa aaattgaaaa tcaactcaat ccctcccgac gaaatcaacc caaaaatcgt
     4921 caaaaagaaa ccaatcaaac attcacttct agaaattttg acccaacaaa ctttctaaaa
     4981 agatgaaaaa gaaaccgaaa attttttcta tttctcagtt tcttttttag ggggcagtct
     5041 tccagcaaga tttgcaagtt accggtaact tgcacaaaaa aagaaaaatc cgcttgtgcg
     5101 aatccttctt tttgcatttt ggggcgctgc cccaatctcc aaatatcggt tatttaatag
     5161 cgtggtaact caaaaaaata gaacgtactc tgaaataaaa aaagactgct ctaacgagca
     5221 gccaataaaa aataatgagc gtttattctt gaaaaagcag cgcgcttatg aagcgctgcc
     5281 aaaaatttac catattttat gaaaaataac aagtttctaa aaaggaatcg gttaagattc
     5341 acaaagaatc gtaaacagac aatagcggaa aatcaagctt ttgtacgtgt gttttaacta
     5401 gaccaatgag aaatcacaaa gtccgtccct gcacccgttg gtagaggggc aacttgggct
     5461 agtcgacatt atgttaacta acgctataaa taacgattat gttcccaaaa caatatttta
     5521 tgaactataa caaaaatttg ttatcgcata ttgtatattt taattatagg tgtataccac
     5581 ttaaatttaa cacaaaggcg tgattatttt gaaacccaaa aagaaaattt atctaggtct
     5641 cctcttttcc ttgatgattg gaatttttag tataggaatt acaaatacct atgcttcaga
     5701 aaattctaat ttcaatatca actcccaacc aattgaagaa caagcaatta attttgcgaa
     5761 aactgatttt gaacactcca taacttcaat tcttttaatg gaaaataaca ccgaaactga
     5821 tattaactat actcttggtt cgccatttaa aatgctcgat ggagaaaata cggcaaatag
     5881 ttctattttc tttccagtat tttcagacgc tgataatacg attaaatata tttataccgt
     5941 c
//
LOCUS       DAIGSZ010000107         5903 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.111, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000107 DAIGSZ010000000
VERSION     DAIGSZ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.111"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(364..1482)
                     /locus_tag="NOB31_002695"
     CDS             complement(364..1482)
                     /locus_tag="NOB31_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974861.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1953..3260
                     /locus_tag="NOB31_002696"
     CDS             1953..3260
                     /locus_tag="NOB31_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCI0974862.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3379..4578
                     /locus_tag="NOB31_002697"
     CDS             3379..4578
                     /locus_tag="NOB31_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCI0974863.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4605..5873)
                     /locus_tag="NOB31_002698"
     CDS             complement(4605..5873)
                     /locus_tag="NOB31_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HCI0974864.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
BASE COUNT         1813 a         1251 c         1058 g         1781 t
ORIGIN      
        1 taaacggtgt tccagaagta gcttcttcgg aaataagccg aaatttcaca aaaatttgag
       61 aaataatttt tgtcaatctc ttcttatttc ttgaagctga ccacttctgt cacaacctct
      121 tccttaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaccaaa caaaaaatat
      181 gaagagctat ttttgcttgc tgttcttatt acttgatgca gaacagcttt ttcacaacct
      241 ctcatacacg gtgtttaatc agctgacctt cggtattagc tcaaaaaacg gaaaaatatg
      301 tgaaactatt tttccgtttg tttctctaat actcaggtca aaacactgat ttcacaacct
      361 cttttaataa cgaagaatcg ctgtcagact cttttcatct ggcgcatctt tttgatccaa
      421 aataaacact ttcccgccat taatgatcac atcatctgct aatgcattca acacttgacg
      481 ccgatcatat tctgtttcag gatcttcacc gaaaccatca gctaagtttg acgtagcgat
      541 aaataaatgt gacacttttc cttctttcgc agctggaacg atatcaacta actgatcgat
      601 gaatttctta tctaagagtt tattgtattc ttttgattct tgagctgcga gttcacttga
      661 cagcttcttc gccccttctt cgatatctct aaaggatagc tgcgcaggag aagcagaaat
      721 cgcaacgtct gcacaataat agggattttt agcaattttt ttgaacatcg tctgattttc
      781 tggtaatgca aataaataaa tcggccattg ttcaggattt tcgaaagaat ccttcaagta
      841 cgtatcaaca gcttggtaat agttgaccca atcgatctct acttcttcat cttttggatt
      901 tacgccatgg aaagttactc catctcgggc tccgcctcct ccattagaag agaagttcaa
      961 accgccacct gtcagttcag atcccaatgc agtaacgaca tcaaccggtg ccccttctgg
     1021 tagagatact tcttttactt gtttgttgct gacctcatac aatttcatgg agtcgcggtt
     1081 caatcccaat aaataataag aatagttgaa ctgcccattt ttgataatag ccagtaaata
     1141 aggaagatca cttacatagt attgatcgtc taccgggata ctcaaacgat ggatataggt
     1201 ctggtcagca gttataatga ccgctacact cgtagttgca ctacgccaaa acgaaggatc
     1261 tcctaacaaa ttttcaattt tttcttggaa cggggaccag tcatgttcgg aatatttttt
     1321 ctcaaaacgt ttctttgctt ctttcgcaaa atttttgaat ttgatctgat ctttttccac
     1381 atcttgatgg gcgacatgcg tattcagcat gatcgtgacg aatggtcctt tagcgccttc
     1441 tgaagtcaat tgtgtcaata attctttatc cttttttgcc ataaacgtac ccctcctaaa
     1501 aaaatcattc ctttgtttct atctaaagtc taccacaaca ctatttttcc atacaataaa
     1561 acgtatctaa aaaaataaaa cggtttctac ggttttaaat ttagctattt ttttaagtta
     1621 tcttcataat ttcctcaatt atttagcccc agtcttcaac tattcttcat gaaatgctga
     1681 taaactaaga aaaagaataa aagaggtgga tcttatgcat ttgattatga ttttcagttt
     1741 attaagtatt atcagtttat ttgctttcag cgcttcccgc ttattagatg cggaaacaca
     1801 gcctattcct gtaaaagtac gtaaaaacga ccgctaaact tccataacgc gcgttcttat
     1861 cctaaagttt tttcagaaac attgaaactc tctcccctct ctgataaaat tttaatttgt
     1921 agcgaaacaa attaattaca aggagatcgg atatgtccat aaaaaaaaca cgtctagtcc
     1981 tattattggc tagtctcatt ctttgccttg cttcttttct accagctgtt gctgtgcaag
     2041 ctgaagatac gttcaaagta aatgcaaaag cagcttttgc tgtagatgcg caaagcggta
     2101 agattcttta tgatcaagat ggagaaaaaa ccatggggat cgcttcaatc acaaaaatca
     2161 tcggtcttta catcgtcctt gatcaagtaa aagaaggaaa actgtcatgg ggtgataaag
     2221 tttcgatttc agattatgca gaaaatttga gtatcacccc agatttatcg aatgttcctt
     2281 tgcataaaga aaacacctac actgtcaaag aattattcga ctctgcaatc atccagtcag
     2341 ccaatgcttc aatggtggcc ttggcagaaa aaatctctgg cagcgaagct aaattcactg
     2401 aacgaatgaa agaacaattg aaagattggg gaatcaaaga tgcaacaatc gttaatgcat
     2461 caggattgaa caactcttat cttggcgaaa accgaccaga aggcactgga gaaaacgacg
     2521 aaaatcaaat gtctgctcaa gatgtggcca tcgttgcccg ccatttgatc ttggatttcc
     2581 cagaaatact ggatgtatca agtactacga cccaaatgtt tggcgaaaat acgcaatcac
     2641 cagtggaaat ggtcaactgg aactggatgc tcccaggatt cgttaattac aaggaaggcg
     2701 tggacggatt aaaaactggt acgactgagc ttgcaggtgc ttgtttcgtt ggtacgatca
     2761 ctaaaaacga tcaacggatc atcactgtcg tattgaatgc ggacggccat gcggaaaacc
     2821 cgagtgcccg cttcaatgaa acagaccgtt tgatggacta ctgctatgac aattggtcag
     2881 aaaaagagct cggaaaagct aacgcaagta ttcctagtct aaaaaccatt gatgtaaaag
     2941 acggaaaaga atcaacagtt cctgttgtgc ttaaaagccc tgtaaaagta tgggtacgaa
     3001 acgatatgga tactggcaaa ttaacgatca cgccaacact tgacaagaag caagtcactg
     3061 acaatgagat ccaagcacct atggataaag gtacaaaaat cggtaccgct acgatcacct
     3121 tggcagacga taaattaggc tatttagaag acaacaatgc accatcaaca gagatcatta
     3181 cggataaaac agtggaaaaa gcgaatatat tcgtgattgg ctggcgacgc gtcgcagaat
     3241 ttttcggcaa cttgttttaa ttgaacaata agaaaaacat ctttccatcg gaaagatgtt
     3301 tttttgcttt ttctagttta aataacagct tttttcatct attttcgtta tactgtataa
     3361 gaaaaaggag ttgaatttat gaatctaacc agagatctga tctttttagt tctctatctt
     3421 attggggtat tctctatcgt ttattggcga aaacagaaga aggatccttc cttgttcttt
     3481 tacggcagta cgtggacatt tacggtaatc ttaacttatt ttgtcgtgtt ggaaattttt
     3541 tattcgacct tttatttttt gattccattg ttgttcttta gtatctttgc tttttcttat
     3601 ttcacagaaa aacgaaggct actgaatggt cttttattca atgttttact catcagtttc
     3661 ggcatctact tgtttgtctt gctgtatgaa acgcaaaata tttttcttgg cggactgatc
     3721 gccttgatca cgattccatt gctacttgtc cttttatttg gtatttatgg attgattgtt
     3781 tttctttttt ggaacggggt cacagtttta cgtagagaat cgcattcatt agctaatctt
     3841 ttaacgttga tactagccat ttttcttaca ctgtttcttg tttttgactt tttcttgtta
     3901 aaatatttgc cgcaatggat aaatgctttg tttttctgcg ttcccctgat cttgatctat
     3961 ctatttatcg tattctacaa ctttttgact gtctcattct tgtatcagtt caaccggcct
     4021 cgatacaatc aagacttcat cgttgtgtta ggcgctggat tgatcaatgg agaaacagtt
     4081 tctcctcttc tagccaagcg aatcaataag gcaattgctt tttatcgggc tcaaagccgt
     4141 gctacattaa atccgcccat cttattgatg tctggcgggc aaggagcaga cgaaaaagta
     4201 ccagaggcca ttgcgatgaa acaatatgcc atggaacaag gaatccctga aagagacatt
     4261 cttgtcgaaa ccaattcgac aaccactttg gaaaacatgc tctattcaaa ggaaatcatg
     4321 gatcagcaaa tgaaagggcc ataccgcgcg atctttagtt ccaacaatta ccacattttt
     4381 agagccggtc tttatgcgcg gcaagccaaa ttgaaagcaa atggtattgg tgcaaaaaca
     4441 gctttctact acttgcctaa tgcgttttta agagaatacc tcgccatctt gatgatgaac
     4501 aaaaaaagac atatgatcat ttgcggattg cttttcgcag gctccgcatt cttatcgctg
     4561 attactttac ttttctaaaa aaacaaggtg tgacaaaaca tatgtcacac cttgtttttt
     4621 tctttcattc tcttaactat tggcaaaaag agtatccctt ttttgaccgc tacttgctga
     4681 gcagaataaa taccgctgtt gcctgaacac ataaagctga tcaagcagat cataaagaag
     4741 tatactgccg cttgtgaacc gaacaattcg atccccatca caaagcaggc aatcggtgta
     4801 tttgtcgcac cagaaaatac tccgataaag cccaatcctg caagaaaagg aacagaaaca
     4861 tggagcaaag gcgctagtgc tgcaccaagc gttgcaccaa tttcaaacaa tggtgtcact
     4921 tctccccctt gatatcccgc gcctaaagac aaaactgtga agaataactt cccaataaaa
     4981 tcatagacat gtgcctgtcc attaaatgat tcttgaagta acggaagact caatccgaga
     5041 taacgttgtg tttgcaaaat caatgctgct gccacaacta cagctccacc tatcgtattt
     5101 cgacaaacag gatgaggaat ccattgtgca tatcgcgctt ttaaaaagac gatcgaacgg
     5161 ctgaataccc aaccaatcaa accaaaagca atcccagcaa caaaaacttt gaagaacagc
     5221 aacatactcc attcaggaat cacacccatt tggtaatgta gatgagaaac accatagctt
     5281 tctgtcatga aatttgcaaa cagtgcagca aagaagctag ggaagatcgc ttctgttcgg
     5341 actttcccga ttgccaacac ttctaatcca aataatgttc cagctaaagg tgtgccaaat
     5401 acagaactaa aacccgcact gattccactg ataatcaaga tttcccgttc tgatttatcc
     5461 aatcggaaca aacgtgccgt attatctgct aacgctcccc ccatttggac tgctgttcct
     5521 tcacggccaa cagatccccc aaataaatgg gtagttatgg ttccaaacag tgtaagtgga
     5581 ataagccgca acgggatttt ttcttctcca ccatttcctt gatcgatcac taagttgttt
     5641 ccacgactag aaagtccgcc gtgatacgca tagagataag caaaaagcgc accactaact
     5701 ggtagtagac aaaggagcca aggatgtgat agtcggatat ctgtcacaac tgtcaggcta
     5761 tttaagaaaa aagcagacaa gctccccatg aatataccga gaatcgctgt gatcaccagc
     5821 cacttcagca tatacactaa aatgcgtact ggactcggta attgtttttc cataaaaaat
     5881 tcctcctcaa taaaaaaacg cct
//
LOCUS       DAIGSZ010000108         5882 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.112, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000108 DAIGSZ010000000
VERSION     DAIGSZ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.112"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(1..191)
                     /locus_tag="NOB31_002699"
                     /pseudo
     CDS             complement(1..191)
                     /locus_tag="NOB31_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            212..1414
                     /locus_tag="NOB31_002700"
     CDS             212..1414
                     /locus_tag="NOB31_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HCI0974865.1"
                     /translation="MCTKLLQNTAHKNPYKTVDEATQLDLVIVVNQLLTGYDSKWVNT
                     LYLDKSLEYQNIIQAFSRTNRLNGPEKPFGTIRYYRKAHTMEQNIEEAIELYSGKQAK
                     GLFVEKLYNNLEKLNDIFEEIKSVFNISGIENFSHLPEVPGEIKQFVNLYNQLIHCYE
                     SAMIQGFTWAKSTYEIQDYEPITVVITEYEFNILAQRYSEIEREPRDGNDSIAYDIDY
                     QLPEGSRSRINYEYLNTNFKKYMNIKEERDSNLIQSLLNDLHRTFAQLPVELQPYAEM
                     ILNDVNNGELVIKEGWEFTDYLNEYQLSEEDDFIQDLVDSTNINEALLREMLDLRLTE
                     VNINEYSRFDKLKSSVNVGHFSGYIEKNLGKMVIPIKVNMLIDRLLRAFLLEDVFDVT
                     EYIKNYFN"
     gene            2147..3115
                     /locus_tag="NOB31_002701"
     CDS             2147..3115
                     /locus_tag="NOB31_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0974866.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            3126..3941
                     /locus_tag="NOB31_002702"
     CDS             3126..3941
                     /locus_tag="NOB31_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HCI0974867.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            4009..4719
                     /locus_tag="NOB31_002703"
     CDS             4009..4719
                     /locus_tag="NOB31_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0974868.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            4755..>5882
                     /locus_tag="NOB31_002704"
     CDS             4755..>5882
                     /locus_tag="NOB31_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HCI0974869.1"
                     /translation="MKQVLRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         2019 a          884 c         1188 g         1791 t
ORIGIN      
        1 gttttaagca actgacaata gctggcattc atgtccatca ctaggtactt gacctttaaa
       61 cgggcctttc taggaaagcg caggaagtat tgagttagtt tgtaaagtct gcgatcttca
      121 agggtcgtaa atagctgatt ggttgtccca tcaacacaaa taaaactcat ggaaccagaa
      181 gtggcaacat tgtgtacttt tctttgcaat cttgtgtaca aaactattgc aaaacacagc
      241 gcataagaat ccttacaaaa cagtagatga agcaacccaa ttagatcttg ttatagttgt
      301 taatcagctc ttaacgggtt acgattcaaa atgggtcaac accctatact tagataagtc
      361 acttgaatat cagaacataa ttcaggcttt ttcacgcaca aatcgtctta atggtcctga
      421 aaaaccgttc ggaaccattc gttattatcg taaagcacat acgatggaac agaacattga
      481 agaggctatt gagttatact caggcaaaca agcaaaaggg ttatttgttg aaaaattata
      541 taataactta gaaaagttga acgatatatt cgaagaaatt aagtccgtat ttaatatttc
      601 tggcatagaa aacttcagtc atttaccgga ggttccaggg gaaattaagc aatttgtaaa
      661 tctttataat caactaatcc attgttatga atcagcgatg atacagggat tcacatgggc
      721 aaaatcgact tatgaaatcc aggattatga acctataaca gtagtaatca cagaatatga
      781 atttaatatc ttggcacaac gttacagcga gatagagaga gaacctagag acggaaatga
      841 tagtatagcg tatgacattg attaccaatt acctgaaggt agtcgtagtc gtattaatta
      901 tgagtattta aacacaaact tcaaaaaata catgaatata aaagaagaac gtgattcgaa
      961 tttaattcaa tcattgttaa acgacttaca tcgcacattt gcgcaattac cagtggagtt
     1021 acagccatat gctgagatga ttctaaatga tgtaaataat ggggaattag ttatcaaaga
     1081 aggatgggaa tttactgatt acctcaatga atatcagctt agtgaagagg acgattttat
     1141 ccaagattta gtggattcaa ccaatattaa tgaggcatta ttacgtgaga tgttggattt
     1201 acgcttaacc gaggtaaaca ttaatgaata tagtcgattt gataaattaa aatcaagtgt
     1261 taacgtaggt catttcagtg gatatatcga gaaaaattta ggtaaaatgg taataccaat
     1321 caaggtaaat atgctaattg acagattatt gcgtgcattt ttattagaag atgtattcga
     1381 tgttacagag tacataaaga attactttaa ctagagtaca cctacatctt atagtacata
     1441 aaaaaattca tcttttttag tttaataatt caccaaaaag gtgagtaatg ccatttttga
     1501 aaattgagct tgttttatgt ctacatctgt atccgtatat aatccaaagg attataaact
     1561 cagaagagtc tttatttttt ctgaatataa ctactgtatc aaaaacaatc gattatgaga
     1621 caaaacaaaa tgacctcttt tatttaagaa aggaggtcat tttttgtatc ataaattgta
     1681 ttaaaatcaa tgtatcactt tttaatcaat tttaagacca taaattgcgt actaaaagaa
     1741 attctgcaat tcaaaataaa gcattttaag ccattttcaa atttaagtgc acccatctac
     1801 ccgtcaaatc actttatttt ccactccagt agtttcctaa ttcaactgtg tgcaaaacga
     1861 tttcttctaa acaaatcaag acaaacttat aaaccttcat cccagcacca taattattta
     1921 aatcataggc atttttcgaa attagtatat gtactcaagt ttcactgcag attatttata
     1981 ttttttagag aaataaattt ttcctattga caaacacaaa gaaagcggat acaatacaat
     2041 tatgtcacat gacgttatat gacgttatgt aatatcttta catttaatca gttactttta
     2101 ttttggataa aattaacatt tttaaaattt taaggaggaa atgttgatgg atgtagcaaa
     2161 aacggttaac gcaattgtag aaaaaaatga tggagagatt tctggaattt atttggtggc
     2221 ttgtggcggt tcgctggtag atatgtatgt ctcagattat tttcttaaag ccgaagcatc
     2281 gaagtgtatt acaggcttat atacagcgaa cgaatttaac catgtaaccc caaagcaatt
     2341 agatgataaa tctgttgtca ttctatgttc tcatggagga aatacagcag aaacggtaaa
     2401 agcaggagaa gtcgctcaag ctagaggagc tgtgactgtt ggtctgactc ataataaaac
     2461 tgcggattta ttaaaggttt ctgatcatag tttcctttac gaatggggag atgatgcaaa
     2521 aatagtcaat aatcctatgg ccatcattct tgatttaact gtatctttgg tcaatgttac
     2581 cgaaacattt gaacattacg gtaaattcag agaaggcatg aaggttatcg ataccgtaat
     2641 tgaaaatggc attaagcagg tgcaggatcg tattaaagtg tttgctgata agtacaaaga
     2701 tgaaacaatg ttttatatct taggtagtgg accatcatat ggacatgctt atggtttttc
     2761 aatttgctct ttgatggaaa tgcaatggct tgattcaact tctgttcatt ctggagaatt
     2821 cttccatgga ccttttgaag taacagacaa agatacgaat tttattctct tgatgagcat
     2881 tggacgcact cgtgctttag atgaacgggc aaaacgattc cttgataaat atgcagaaag
     2941 agtagaaatc gttgatgcaa aggaactagg attggatatg atatcagatg aagtttctga
     3001 attcttcaat cccattttat tctacagtat tctttcagaa tatcgttcag ctttagcaga
     3061 tgcacgcaat catgatttag atgttcgtcg ctatatgggg aaagtggagt actaggagga
     3121 ttaaaatgaa ggtattaggc ttaggtgata acgtcgtcga taaatatgaa aatctgggaa
     3181 ttatgtatcc tggaggaaat tcattgaatt ttgcagtttt tgcaaaaaaa ctgggacatg
     3241 aaagtagctt tatgggagtt tttggctcag atgaggaggc agctcatgtt ttatcagcaa
     3301 taaaaaaaat aggactggac aacagtcact ctcgctttga aaaaggcgag aatggctgtg
     3361 ccagagtgaa gattgatgag ggcgaccgga ttttccttgg cagcaattcg ggaggtgtta
     3421 ctcgtgaata cccgattcag cttactgaag aagacagaga atatttaaac cagtttgaat
     3481 tgattcatat gggattatat agccatgtca atcatctatt agaagagtta caaaatgttt
     3541 ctggaaagat ttcttatgat ttttctgacg actttacgga agaagaggtt cagcgggcaa
     3601 ttgataaagt tgattttggc ttcttttcta tagaagactt ttccgatgaa gaagtaaagc
     3661 agtttttgat gaagcatttt tgtgagcgaa atgatgtatt gattgcaacc cgaggagaaa
     3721 aaacggctat tggttatgat ggagcaaagt tttatgaagt gaaccccgtg ctagaagaac
     3781 cagttgatac aatggcagcg ggagattctt tcttaacagc tttcctactt tattttctcg
     3841 aaggggacga tatagtcacc gcgatgaaaa aggggaatga atttgctggg aagtcttgtc
     3901 tggttgacgg ttcgttcggc tttggtattc attacgattg agcttgtttt aaattcctgc
     3961 atttgataac ctaaagaaag aaatcccggt aaagtggagg ttaaaaaaat gctggataca
     4021 aatgcacaat taccattgta cttacaatta aaagaaatat taaaaaataa aatcaataca
     4081 ggggagtatc ccgagaatac gaaaattccc gctgaatcag agctgataga aagttatgag
     4141 gtcagccgaa tcacagtgag aaaagcagta gaagaactgg tagaagaagg gtacctactt
     4201 aaaaaacaag ggaaaggaac ttttgtcaac cggcataaag tttttcgtaa aattgaatat
     4261 gttatgggtt tcagtgagag ttgtaaatct aatggtttta caccgactag cattgttttg
     4321 gaacgcaaga tcattccagc aactgaaggg atggcaaaaa aactcgatat cgctcaaggt
     4381 gatgatgttt tatatatcca gagaaagcga atggcggata acatccccat tatgttagaa
     4441 aacaattatt tttcttatga aagatatagt ttcttaatgg aggaagagct gactgattct
     4501 ttgtatgaag tacttaaagt ccaaggtacc ttagccatca atcctgggga aactgcactt
     4561 gaaattgtca cagctgatga ccaaattgcc aaaataatgg aagtagctgt tgggacgccc
     4621 tttttcttta tggatacttt aatcaacgat caaaacaaca taccaattca tgtaggtaat
     4681 caatattacc tgggagaagt atatcgtttt tacttatgat ttcctgtttt gatttcaagg
     4741 agtagatttt atttatgaag caagtattgc ggtcaaaaat gatttttgat ggagagcagc
     4801 cacctttcaa aggttatatt gtaatcaatg aagggatcat tgaaaaggtg gaaaacaact
     4861 ggaattacag tgatctatta aatgaaaaca cggaattaat tgcttatgat gatcaattcg
     4921 ttatgccagc aattcatgat aatcatgtat ttttcagtgg ttatttggct atgaatgctg
     4981 gcatagattt aagcgataca tcttcagcta acgaggctgt agagcgtatt aaagctgtaa
     5041 tgaaccataa aaaagcagat gaaccaattt atgctcatgg ctgggatgct gccctgtgga
     5101 aaactgaccc atcagaagag ctattgaatg aaataaacca ctttggtcca atcacagcga
     5161 tcgacaaaaa tcgcagccat tgttggatga atgctattgc taagcagact tatggtttta
     5221 cagaaaaaga aaccagtgct gaaagtcgag tattattaat taaggaaatg ctagcaaaca
     5281 aaaagctttt agcagaggtt tacgctgaat ttgaagcatt actgctttca aaaggtgtta
     5341 tatcaatgaa agaaatcgtt tttgatgacg cagaatttct ttctaatata cctcagagga
     5401 aaatacttag taacctatat gtgcaggcag tccaagaacc tctacagcat gaacttctat
     5461 atgagtataa ggaaaaagtt ttccctgaaa aggtccgctt tggtggagtg aagatcatgg
     5521 tagatggtgt tgttgcggat agaagtggag atatttacgg tgtttatcag tcaggagtag
     5581 cttcacccga gattgactat gaggcaatta aagcagaagt tgctgcattc aatgaagtag
     5641 agattccttg ctgtttgaca acggaaggag ataaagcggg ttataaagct gcgtcaattc
     5701 ttgtcgaatt tggaaagcgg ttacctgaag gcgtttttaa ttcgattagt gatttggaaa
     5761 tggttactca aaagacagca gaaaaaatga acgaaggaca agtagtagca gaggtatatc
     5821 cacaaattct cggcttgaat caaacgttag aagaggctta catgtcaact gttataaaaa
     5881 at
//
LOCUS       DAIGSZ010000109         5877 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.113, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000109 DAIGSZ010000000
VERSION     DAIGSZ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.113"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            641..1375
                     /locus_tag="NOB31_002705"
     CDS             641..1375
                     /locus_tag="NOB31_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCI0974870.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1391..2560
                     /locus_tag="NOB31_002706"
     CDS             1391..2560
                     /locus_tag="NOB31_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCI0974871.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2576..3571
                     /gene="lacD"
                     /locus_tag="NOB31_002707"
     CDS             2576..3571
                     /gene="lacD"
                     /locus_tag="NOB31_002707"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HCI0974872.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3650..4576
                     /locus_tag="NOB31_002708"
     CDS             3650..4576
                     /locus_tag="NOB31_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HCI0974873.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4595..5845
                     /locus_tag="NOB31_002709"
     CDS             4595..5845
                     /locus_tag="NOB31_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCI0974874.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1967 a          955 c         1204 g         1751 t
ORIGIN      
        1 gtttgaaaaa tgctatttcg aggtagaagg atattatata agcacggttg actaaacgaa
       61 gtgataataa aaaaagttat tcaagaataa gaaaaattat gatacgaatt cagataaact
      121 ggagaataca gagaccttta aaagggataa gaaacaacat aaattcctct taagagagaa
      181 cgaaaggaca aagccagcaa cttgatacac gagctagtat tagaggaatt tattctcata
      241 gactcccttt tgaatacgtt tcaactttaa ttttcatgtt cataaatgat ttgaaaccaa
      301 agcaaatgcg ttgcactttt cctccgtctt ccgaaaatcg ttcaattcac tggtaagtag
      361 tcatttgata gtttgaggca aattgttgat tgatgaaggg taggagctaa aaaaagatac
      421 cagttgaaga gagaaaaaga aaaaaataga gggtgttctt gaatgaaaaa agttggaaaa
      481 ttatttttca tttcctttta ttcctattaa agtcagtgat gtcaatcata ttaacaagac
      541 taaaaatgaa aataaaaaaa agattgttct tagtattgac tcataaaaaa taccactact
      601 atacttacat tgtggttata gccagttagg agagacatcg atgcaaaata cctttcaatc
      661 aaaatcactt tattatcagc tggtagaaat attgaaacaa cgaatcgaaa acagtatggt
      721 cgctcatgac aagctgccat cagaaagaga gttgaccagt ttttatggcg ttagtcgcac
      781 gacggtgcga ctagcattgc aagaactgga aaaaatgggc tacatttatc gacaacatgg
      841 aaaaggaacc tttgtttcgg aattaaggac aaatgcgact gatctagctg gcgcatatag
      901 ttttaccgaa caaatgcggg caatgggcaa acatcctgaa accaagatat tggccttcaa
      961 gaagattgaa gcaactaaat atttagcgag tcatctgaat gttcaactag gtgagccttt
     1021 atttcaatta gaccgattgc gcttagctga tgatttgcca atgatgatcg agaaatccta
     1081 tttgccagtg aagctattta tgtccctttc tcaagaaatt ctatttctga aacctttata
     1141 taatttgttt tcagagaatt tcaatcaaat cgtacggttg gctgacgagg aattttatgc
     1201 cagcattgtc cagaaagaag atagtgagtt gctaaatatt ccagaaggat caccagtgct
     1261 ccatttagtt cgctcaacct ataatctcga gaacgaagtg attgaattta cattaagtgt
     1321 agcgcgggct gataaatttc attataagat caggcatctg cgttccacta actgaattgg
     1381 aggaaagaaa atgtttatgt tctcaaaaga agaactacga aagctaggag cagaaaatac
     1441 tacccgagaa attcgacagc aaccggaact gtggcatgag acgtttgacc gttatcaaga
     1501 aacagttgca gatttagatc gtttgtttac ggatgcgaaa caacatgctg gagagcgacc
     1561 aatccgagtc atttttacag gggccggaac ctcgcaatat gtgggagata cactaattcc
     1621 gtttcttact agtcaaggaa atacgaacca gtttattttt caaagtattg gttcgaccga
     1681 tatcgttgct acgccaaaag aatacctgat tcctgatgag acaacgatct tggtctcatt
     1741 tgcccgtagt ggaaatagtc cagaaagtct agccgcagtt aagatggcca atcagctggt
     1801 caacaagatc tatcatatcg tgatcacctg tgcaccagac ggattattgg ctacacaaat
     1861 gcctacaaaa aaagaaaatc tagttttact aatgccaaac aaagccaatg acgctggttt
     1921 tgctatgaca agcagtttca gctgtatgac gctgactgcg ctacttattt ttgatcaagc
     1981 aagcaatcag caaaaagaaa gatatgttca tcaattaagc cgactaggag aagaagtcat
     2041 ccaacgagaa tcagagatcc aagggtatct ggcatcagac tttcatcgca tcatttactt
     2101 aggttcggga agcttaggcg gattgactag agaagcgcaa ttaaaagttc tcgagttaac
     2161 tgctggaaaa atcgcaaccg tatttgatac atctttagga ttcagacatg gtcccaaatc
     2221 ttttgtcaat gagcaaacat tggttttcct gtttgtcagc aatgactcat atacgcagaa
     2281 atacgatgta gacatgctgg aagaaatcaa aaatgacggt attgcccaac gcgttgttgg
     2341 aattggtcaa aagggttcat tgtttagtgg tgattccttt gaattagttg cagattcgtt
     2401 actgccggat ggctatcttg ctttagcaga tatcatggta gcccaaacga tcgcattact
     2461 ttgttcggtg aaggttggta atacaccaga tacaccatcg ccaagtggaa cagtcaatcg
     2521 tgtggtcaaa ggcgtaacga tttatccata tgaaaaatag gaaagagtgt gaagcatgtt
     2581 agaatggtcg gaaaataaaa gacaagcaat ggaacgtcta tcgacgccag aaggcattat
     2641 taccgctttg gcgatcgatc agcgaggcgc gctgaagaaa atgatgtcgg ctttagggat
     2701 ggaagcgaca aaggaaaaaa ttgagcagtt taaaacacta atttcccaag aattgactcc
     2761 ttatgcctca gcaattttat tggatcctga atacggactg cctgctgcac agaagcgtgc
     2821 agcagcgagc ggtctgctgt tggcatatga aaaaactggt tatgatcaaa ccgtacccgg
     2881 ccgcttgccg gatctgctgt cggactgttc agttctgcga ttgaaagagt taggtgcgga
     2941 tgcggtgaaa tttttactgt attacgatta tgaagaagca gaggaaatca atcggcaaaa
     3001 gcaagttttt gttgaacgaa ttggaagcga atgcatggct gaaggactgc cattttattt
     3061 agagttattg tcatatgatg ctaaaaatgt agatacgaaa tcgctttcct atgccaaagc
     3121 aaaaccgcgc aaagtgatcg aaatgatgaa agaattctcg aaaacccagt ataaagtaga
     3181 tgtcttaaag gttgaagtac cagtaaacat gtcatttgtt gaaggaaatg caacagggga
     3241 gatcgcctat acacgtcaag aagctgccgc ttattttaaa gaacaaagcg atgcaacaga
     3301 tttgccgtat atcttcttaa gtgctggggt atcagcggca ttattcatgg agacattgcg
     3361 ttttgccaaa catgctgggg cacgattcaa cggtgtactc tgtggcagag caacttggaa
     3421 agatgcagtc gctcctttcg ttgaaaaagg agaagcggca actttagaat ggctgacaga
     3481 acaagggaca caaaacattc gtcaattgaa tgaagtgata agagaaactg ccatcccatg
     3541 gtatgagaaa gtaagtgaaa gcacttgtta atgtttctaa tatattagta gtgataagag
     3601 atatgtgtga ttataattta tcattattga aactgggagg atattttata tgaataaaag
     3661 attgttagat tattcagctt cagatttttt gaaagctaag ccgatggaat taaagcaggc
     3721 aattttggct tctgaaggta gaacaattat ggcagaaaat gtgccaagta gctgtcctta
     3781 catgggaaaa tcagtgacaa atgcagaatt ggagagagct gctggagctg atttaatttt
     3841 gtttaatgca ctagatcttt ttaatcctca aatttcaggt gtacctttaa ctctaaaaga
     3901 gaatccaata atctggatta aaaaagcttt aggaagagct attggtgtaa atttagaacc
     3961 tgtagacaaa gaagttttga tgagtgaaaa tcgaactgaa atttcaagtg gtagaatcgt
     4021 ttctcctgag actttaaaaa aggcaaatga attaggcttt aattttattt gtttaactgg
     4081 aaatccagga acaggagtat ctaatagaac tattgagaaa gcaataacat tatccaaatc
     4141 aatttttaat ggattaatta tcgctggaaa aatgcatggt gctggtgttg atgaaccaat
     4201 tatgaactta gatatagcaa aaagatttat taaaacaggt gtagatattt tattagttcc
     4261 tgctccatac actgttccgt atttcatgga aagtgatttg cgaggaatcg ttgattatat
     4321 aaaagatttt aatagaaata aatctattga ggaaaaagtt ctagtactaa cggctaatgg
     4381 aacaagccaa gactcttctg accaagaaac tattaaaaaa attgcattag catcaaaagc
     4441 atgtggagct gatattcaac acatagggga ttctttaaat ggtatttgtc ttccagaaaa
     4501 tatttttgct ttgggtcaag caattcgggg atatcgtcat caaattatta tgttaggaaa
     4561 atctaattat cgttaattaa ggaggaaatg aaagatgatc gacaaagttc aaaaaatagc
     4621 tgcaaaaatt agtaatcaaa gacatctact agctttaaga gacagcatgg ctgcagttat
     4681 gccattaatc attattggtt ccttttttat gttattagca aatttcccga tagaaggatt
     4741 tacaaaatgg ttatctgaaa ttggagtaca atcctttttg aacaaagcat cagattcaac
     4801 atttggtatt attggattag ctgttaccta ctctttggga cacaatctag caaagactta
     4861 tggtgtagac tcattatcag caggattatt atctttgagt ggatatgttt tacttacacc
     4921 tttattggat gcagatggtt ctataggatt tccaacaaaa tactttggta cctcgggtct
     4981 ttttgttggt attattgtag cacttgtatc tacagaaatt ttccggtggt ttgtacttaa
     5041 aaatattaca attaaaatgc cggcaagcgt tccaccaaat gtaagccgag ctttcgttgc
     5101 tattattcct ggcttttttg tcgttctact atggtttatt gttgttgtaa tttgttataa
     5161 acttggaatt gaaaatgttc atgctcttat tgcagataca ctcgcaaaac cactatcttt
     5221 actgacgaaa actttaccag gaattatatt ggttatactt attcaatgtt tcttttggat
     5281 gtttggtatt catggtgcac aggtaacggg gccaataatt gaaccgttat tattgcaaaa
     5341 ctctgatgta aatagaattg cttatcaagc tggaaaagaa cttcctaaca ttataactta
     5401 tgaattctta tataactttg ttttttctgg tggtgcaggt tgtttatttg cacttgccat
     5461 tttaacattt ttcttttcaa agagtcagga aaataaaact ttaggtaagt tatcaatcgc
     5521 tccagtaagt tttcaagtag cagagcccct tctatttggg tttccaacta tattaaatat
     5581 aaaaatgtta attccatttg taactgcacc agtagtaaca acattaatta cttatttttc
     5641 aatgagtatg ggattagttg caaaacctgt aggagcaaca atcccatgga caactccacc
     5701 gataattgcc ggatttttag cttctggtgg acgaataagt ggtgcagtga ttcaagtaat
     5761 aacaattgca ataaatgttt tgatatacta tccattcttt aaattagatg ataatgccaa
     5821 gctaaaaagc gaaaaaaatg attagaacta cctatatgtt tctaactgta gttaagt
//
LOCUS       DAIGSZ010000110         5718 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.114, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000110 DAIGSZ010000000
VERSION     DAIGSZ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.114"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            187..1269
                     /locus_tag="NOB31_002710"
     CDS             187..1269
                     /locus_tag="NOB31_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HCI0974875.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            1269..2072
                     /locus_tag="NOB31_002711"
     CDS             1269..2072
                     /locus_tag="NOB31_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCI0974876.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            2142..2882
                     /locus_tag="NOB31_002712"
     CDS             2142..2882
                     /locus_tag="NOB31_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCI0974877.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            2893..3897
                     /locus_tag="NOB31_002713"
     CDS             2893..3897
                     /locus_tag="NOB31_002713"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HCI0974878.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(3942..5639)
                     /locus_tag="NOB31_002714"
     CDS             complement(3942..5639)
                     /locus_tag="NOB31_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974879.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT         1854 a          944 c         1158 g         1762 t
ORIGIN      
        1 caaatcttgg caacatcaaa taccagataa actacaatta aaataaagaa aacaggcgag
       61 tgttgctcgc ttgttttctt tatttttgaa tattctgaat aaaagataaa aataccaagt
      121 ttgcctgaac aaaaatcata agcaatggta taatcacaat atgaatatag aaatggggga
      181 aaacatttgg atacaaaaga agaacagcta cttattgatt taacttctgc aaaaggagta
      241 cctggaaatg aagaagaggt aagagaagta ttcagagaat atgccaaacc attcgctgat
      301 gatatttttt atgacggttt aggcagtgtg attgccaaac atggtgctgg cggaggcccc
      361 aaggtcttta tttctggaca tatggacgaa gttggtttta tggtaacaaa aataaccgaa
      421 aaaggattct tggaattcca aactcttgga ggttggtggg ggcaagtcat gcttgctcag
      481 caagttgaaa tcaaaacacg tgaagggaaa atcgtccacg gtgtgattgg ttccaaacca
      541 ccacatgttt taacacctca agtaagaaat aaaccttatg aaataaagga tatgttcatt
      601 gatattggcg catcaagcca agaagaagcc aaagagtggg gcatacgtcc tggagatatg
      661 gtcactccat atattgaata caaacgaatg aatggcagta aatatttact ggcaaaagca
      721 tgggataatc gtatcgggac agctgtttct ctgcgagtat tagagaatct atctaaagaa
      781 gcacacccaa atgttttatt cgcaggaagc gatgtgcaag aagaagtagg cttgcgaggt
      841 gctcgaacaa gtacacacct tgtaaatccc gatattgctt ttgctttaga tactggtaca
      901 gcaggagaca ctccaggaat gacaccaaaa gaagcagatt cgattttagg aaaaggccca
      961 cagattttga tttttgatgc atctatgatc ccgcataaaa aattattgaa ttttgttatt
     1021 gatgtagcag aggaaatgga tattccattc caatatacag tgatttctgg cggaggaact
     1081 gatgcaggac aaatgcattt gacaagagat ggtgttccgt ctgtagccat taccgttcct
     1141 gttcgttatc tgcattccca tacatcagtg attcatgaag atgattattt gaatacagtg
     1201 aaactagtca cagaattagt gaaacggctt gatagtgaaa cagttgaaaa aattcggagt
     1261 tatgaataat gaataataga atacctattt ctgaatatcg gaaaaaagca cgagtttctt
     1321 tggaaaatca atggggaatc aatacttggc ttgttttctt atctataata tttacgagcg
     1381 tcatccagaa cttttttgac ggtttcagtc cttttccgga agaaagcatg cagcagcact
     1441 tattgagttt tctagtcgat aatttacttt tattcgcatt caactatgca ttgttttaca
     1501 ttgcgctagt agttgtacgg ggtggcagac caaaaagtaa ccttttattt tcagttttcc
     1561 aaagaaagta ttttggttcg atacttggca tcaatttgat caattcagtc atcaactggc
     1621 tactcaacag tttaatcttt ctgcccatgt ttttaatcag cggagtgagt acttatatgc
     1681 agctgctttt cagttcaaat gcggtaccta cgggtgtcat gccagaagat tttcttgata
     1741 tcagctttgt tttatcgatg atagggatga tttttgtttc agcactcatc atgagtattg
     1801 ttggcggttt attccaattt gctgcatgga caaagttcga ctatcctgat ttgtcggtta
     1861 ttcaatgttt gaaatatggc tggtttttat tgaaagatag aattggtacg tatattttgt
     1921 tgcagctgtc ttttatcggc tggtatttgc taggagcaat cgctttgttc atcggtcttt
     1981 tgtgggtcat tgtttatgtg aatgtgtcag ttgcagaatt ttatgaacaa gcacggattg
     2041 aaaaaggagg tccagacgcc tattttactt agcatgtaag cagtttattc atcaaaaaaa
     2101 taacttttgt ggtaggataa atctttgagg gggaatgtac gatgaaatta actgttttag
     2161 gatgcttagg agcgtatcct tataaaaatc aagggacaac aggttatttg cttcaatctg
     2221 acgggttcaa tttgttgatc gatgcaggta gtgctacgct gatcaaatta caagaacacc
     2281 ttgatccact tgatctagat gctgtgatcc ttagccatta tcatcatgat catattgctg
     2341 accttggtgt attacagtat tactggcaac ttcatcctaa gagaaatccg gagacattgc
     2401 tttcaattta tggacacaca aaagattcca ttcactttga agaattgacg ttggaaaatg
     2461 tctcaaaagg acatccttat tttgaagctg aagaattaaa aattggtcct tttctgatta
     2521 cttttatgga aacaatccat ccagtagtat gttacgccat gcgtatcgta gaagaaacaa
     2581 cggggaaagt attcgtattt acaggtgatt caggttattt ggaaagtttc gctgattttg
     2641 cgaaagatgc tgatttgttt ctagcagata cctatctttt tgaaggaaat gaacatcatc
     2701 atgcccattt cacttcaaaa gaagctggag aacttgcgaa atcagctaac gtaaagaaac
     2761 ttgtacttac acacctacct cagtttggtg atttagaaca attgaaaaat gaagcgcaaa
     2821 aggcagcagg caaagggatt gatatagaac ttgctgcagt tgacaaagtg tttaacattt
     2881 aggaggaaga acatgatttt tgtaccaaat gaaaaccacg acccaagaat caatttagca
     2941 attgaacaat atttgctgca agaaatgcct ttagatgaac ctattttgct cttttatatc
     3001 aatgaacctt caatcatcat cggcagaaac caaaatacgc ttgaagaaat caatcgagat
     3061 tatgtggaag aaaatggcat tcatgttgtc cgtcgcttaa gtggaggcgg agctgtctac
     3121 catgattttg gaaacctgaa ctttagtttt atcatgcctg atgatgggga ttcattccgt
     3181 gactttgcga aagtaacaca gccaatcatc caagcacttc atgaattggg tgttgctggg
     3241 gcggaattga aaggccgaaa tgatctagtc attgatggca tgaaattttc tggcaacgcg
     3301 atgtatgcta ccaacggtcg gatgtttgct catggaacaa ttatgttcga ctctgatatc
     3361 aatgaagtag tcaatgcatt aaaagtaaaa aaagacaaaa tcgaatcaaa aggaatcaaa
     3421 tcgatccgtt ctcgtgtaac gaatatcaaa ccatttcttc cagaagaaaa gcaaaaaatg
     3481 acaacagaag aatttcgtca agaaatcttg ttgaaaattt tcggcgtaga gtcagtagaa
     3541 gaagtaaaaa cgtacgaatt gactgatgaa gattggaaaa aaatcaatcg aatctctgag
     3601 gaatattatc gaaattggga ttggaattac gggaagtctc cagatttcaa tttctctcgc
     3661 caaaaacgtt tttctatcgg ttcgattgaa gtccatttga atgtctcaga aggaatgatc
     3721 aaagaagcaa aaatctttgg cgatttcttc ggactaggag atatctctga cgtggaaaaa
     3781 aaattggttg gacagaaata tgataaagca tctctatcaa aaatagtcag ccaaattgat
     3841 gtgaagaaat attttggtgc gatagaacca gaagaattgc ttaccttact ttattgaaaa
     3901 taaaaaatag cggaatccac atatatggat tccgctattt tttatacagg attcgggtaa
     3961 tttcgagaga gttgaacagt gatccgatca atgaaagtat ctttttcctg cgttagtgtt
     4021 cctgtgtaac gatccgctac gtctttcatc atcattaagt caaaacgttc ctgatcatct
     4081 aattcttctg tgatgcctcg actaaatagg tttgtatcgt aatgtgcact atgttcgcaa
     4141 caaatgacga aatgttcctc ttgttcgtgt atcgacaaat aaatttttcg atacagtgga
     4201 ttttcgatgg catgagtttc tctaaaggaa tgctctaaag cgtggatcaa aagttgagcc
     4261 agatcgtcat cgttgatagg aagttcttcg ggaagatctg cttggaaggt tatctgaata
     4321 ttccgtttgg cagctaactt ctggtaacgc gctaagataa gatttgtcac ctggtggttg
     4381 caaaaagaac acagcatttc gaaatttttt gcttcttcta atatcttttc cacatagttt
     4441 ttagcttttg tttggtccgt atgcattaaa tcttgcagat tctccatctc ttggacaaat
     4501 tccaggcgaa gtgtatttac ttcttggata tgctgtcgaa gctgctcata atgttgctcc
     4561 aacaaatcat ttttgatttt taagaaatct acttgtctcc gatctttgtc ggtatttaag
     4621 atgtgatcga ttagattgta gctgataata acgattagaa tgataatata taaaatcgta
     4681 gaccaattga tcgttgtttg atagatacct aatgccgttt ggatgtaaat caagcaatgg
     4741 ataatggcta ccaagacgat ccaaggtgta caagctacat aaaaacggtt attcttatat
     4801 gcttcgccaa tgcatgcaag tgaagtgact aaagtgctta taacactagc aatattagca
     4861 atcggcatta attcaggaag ttctgcagga gtaaaagttg cataaagcag aacgccgata
     4921 aaaatcaaaa gttggaacgt acaaaaaatt ccgtaccatt ttttatagta aaacattcgg
     4981 ctccaatagt agcagatgat gaaagctgac gttaagataa taaataaatg agataaaaaa
     5041 gaatgaacga atggttcaaa aagaatacca cttaaaatat cttctgatac agcttcaaat
     5101 cctaatgcca aagcaaagca acttaagaga ataagtgagt attcaagacg tttttgttta
     5161 tacatcaagt agatcgtata gaaaaaggtc cctatagcga taaaaacagc gattatcatc
     5221 gtcaatactt gcggcactga ttgtgaataa ataaaactaa tcaatggtcc agttgttcct
     5281 agataaactt tcggtggcag tccagcatag ttctgataag gagatgagac tgtaagggtc
     5341 aatttttttc cgatataatt tgctggtaaa tctatcacag ccaatgagag tccgggattg
     5401 ctttcttcct gataatcttt ccgttggtat aaaatctttt cgcctagata tacagtaatc
     5461 cattgatggt ttcctttgat tagtaaattt gcttcgtcca acggtttttc aagtgtcgtt
     5521 tccataatga atgtttcgtc tttatccacg gtaggaatcg tacgagtgta cttgctgtca
     5581 aacttaaaat caggatcatc ttttgtatag aaaacccacg aatcttttat ttctttcatt
     5641 tgattgctgt ccgcaggaga aaaaataaaa taaaagaaat aagcaattcc tgttaaaaat
     5701 aacaatgata atataatg
//
LOCUS       DAIGSZ010000111         5669 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.115, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000111 DAIGSZ010000000
VERSION     DAIGSZ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5669
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.115"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(1014..1304)
                     /locus_tag="NOB31_002715"
     CDS             complement(1014..1304)
                     /locus_tag="NOB31_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974880.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1706..1942
                     /locus_tag="NOB31_002716"
     CDS             1706..1942
                     /locus_tag="NOB31_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974881.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="NOB31_002717"
     CDS             1949..3901
                     /locus_tag="NOB31_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCI0974882.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="NOB31_002718"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="NOB31_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCI0974883.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4797..5489)
                     /locus_tag="NOB31_002719"
     CDS             complement(4797..5489)
                     /locus_tag="NOB31_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI0974884.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1851 a          983 c          908 g         1927 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agcaattttt tctataagtt atattatcat aataccacaa aatcacaaat tttcattcaa
     4621 ttatcatttt caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa
     4681 atgaaaaaag tagtccattt tgaagtacat tttgtcattt tgtactccaa aactgaacta
     4741 cttagtatag attactgttg cttctttact aatttaggtt tacttgttaa gaaagattat
     4801 ttacgcaaat gttcttcaac aatttgctga gatttatcag ctgtatcttc cacttcatct
     4861 tttgcttttt ctaacttttg aatatattgt ttcaagcttg agttttcagc agttgcttcg
     4921 tctaatttct tttgtgtatc tgttaactga gtttctacat ttgttttttc ttgtgtcagt
     4981 gttgcgattt gttgattcaa accatttaca gtattttgta attctgaaag ttttgcttgt
     5041 gcttcttgta gtcttgctgt ccaatctgca ttcagatgat tgatttcatc atttttttgg
     5101 ttgatctcat ctagtttgac attgatttca ttttgtttgc tttgtagttg tgcatccttg
     5161 ctgactaatt gactttctaa gttttgtttt tctgctgccg attgattttt ttggttttct
     5221 aattcattta cttttgtttg gtattcttgg acatctgcct ttgaatcttg caatgtctgt
     5281 tctttttgtg ctagtcgagc ggtaagatct gtaatcgctt gctctttatc tgtcaatgta
     5341 tgatcaagct gtgtcagatt ctcattgatt gtatcaatat ctgtctctcc accccacaaa
     5401 ataatttcat ttgcgtaccg cgtgcctgtg tagccaatta gacatagaaa tgcaacgaca
     5461 atcccaccag taataaattt ctttttcatt tgcatagctc cttaatccaa tacttttaca
     5521 tgctaaaagt aagtgatctc aaacacaatg tcaagcgttt ttaaattaca tatgtaattt
     5581 taatataaat actatcaaat actcatttaa tcctcctttt ttatctattt aaaaaatctt
     5641 ttttatagag aaaaatgcag gttaatact
//
LOCUS       DAIGSZ010000112         5312 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.116, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000112 DAIGSZ010000000
VERSION     DAIGSZ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.116"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="NOB31_002720"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="NOB31_002720"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HCI0974885.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="NOB31_002721"
     CDS             complement(1297..2133)
                     /locus_tag="NOB31_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0974886.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="NOB31_002722"
     CDS             complement(2317..3534)
                     /locus_tag="NOB31_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI0974887.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3683..3862)
                     /locus_tag="NOB31_002723"
     CDS             complement(3683..3862)
                     /locus_tag="NOB31_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974888.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3917..4000
                     /locus_tag="NOB31_002724"
     tRNA            3917..4000
                     /locus_tag="NOB31_002724"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..4818)
                     /locus_tag="NOB31_002725"
     CDS             complement(4240..4818)
                     /locus_tag="NOB31_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974889.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(4824..5207)
                     /locus_tag="NOB31_002726"
                     /pseudo
     CDS             complement(4824..5207)
                     /locus_tag="NOB31_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347134.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1654 a         1081 c          838 g         1739 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagttaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca ta
//
LOCUS       DAIGSZ010000113         5302 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.117, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000113 DAIGSZ010000000
VERSION     DAIGSZ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.117"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(449..952)
                     /locus_tag="NOB31_002727"
     CDS             complement(449..952)
                     /locus_tag="NOB31_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCI0974890.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1075..1839)
                     /locus_tag="NOB31_002728"
     CDS             complement(1075..1839)
                     /locus_tag="NOB31_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HCI0974891.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            1947..2222
                     /locus_tag="NOB31_002729"
     CDS             1947..2222
                     /locus_tag="NOB31_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HCI0974892.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            complement(2423..2770)
                     /locus_tag="NOB31_002730"
     CDS             complement(2423..2770)
                     /locus_tag="NOB31_002730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974893.1"
                     /translation="MIPSVSFLFKKLKTFFILPEIEESNELTASDRSAFLLPVFNTWG
                     KAPQKQPYRRCSKVSFLVLRQIYAKMWKAIFTKFSLILKTKRLFHNQSLMLDADQLFH
                     NLIDGVLSAASRY"
     gene            2938..3867
                     /gene="yidC"
                     /locus_tag="NOB31_002731"
     CDS             2938..3867
                     /gene="yidC"
                     /locus_tag="NOB31_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCI0974894.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQPKNSTNNKGRNAGKQQKRK"
     gene            3970..5302
                     /locus_tag="NOB31_002732"
                     /pseudo
     CDS             3970..5302
                     /locus_tag="NOB31_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT         1684 a         1006 c          983 g         1629 t
ORIGIN      
        1 attataaaaa aatattggta tggttttatt gtttgttcca tgattttaaa gtcctttctt
       61 ctaaccaaag tgcatacttt gtagaaaaaa gtgatcttct gcaaagtatg tgttacctga
      121 agatcctgga ctcttttaaa taagatacgt tttgcatctt atcatcaccc cctttaatgc
      181 ttattattct atgtacatga ttcattcgat aaataaaagt aaaccgtatc ttgaacagat
      241 agtcaactgc aaacagaaaa aaggactgtg acaaaagtcg tgtcaaagtc ccttgtttcg
      301 aatgaatggt gttcaaaagc ttgcatctgc agtaataagc cgaaacttca caaaaatttg
      361 agaagtaatt ttcgtaaatt ccttcttatt tcttgaagct gaccacttct gtcacaacct
      421 caatatggtc tattattggt tttacctgtt aaatcgagga ttctttccca aagtaacgtt
      481 gccatctctt acgcatactt gcagacatgg gctgagccgc ttctttgact gcgcagtatt
      541 tgtccacgaa tgtcacaata tatccttctt tatacttagg cggtgcgatc gttgcacccc
      601 acatgtgctt caaaatgata tctcgctcaa gatccgacaa atcggtgatt ttttctgcat
      661 tctttacagc aattcttgga tggatatacg catgtgtccc ctcgtcaaat ttcgtcgtac
      721 gccaatcata gtagaacaga tcatgcaaaa gtccagcacg cgctgttgct ttagcattgc
      781 caccccattt ttttgcgagc agataactat agtaagaaac actgatggaa tgctccaaac
      841 gagtggaatg aacatgctgt gtgtaattcg ctaatttttt cactgcttct gtttctaaaa
      901 gatcttgtac ataagacata tattcttcgt cttcacgcca tttttctgtc ataattatcg
      961 atctgccacc tttttgaatt tcattttctt ctgaaattga tctaagtata ccaccagtgt
     1021 tcggattatt ctagtcgctc tagataaaat agctaaagct taatagttcc ttaatcataa
     1081 agaaaaatga taaagaacga tccctgctgc gactccgaca ttcaatgatt ccgcatttcc
     1141 tttcattggg atatatacgt tctgatcagt caaagacaag atttcctgac tgactccctg
     1201 accttcgttt cccatgatta tagcgaaatc ctctgttttt tctactttgt ctaatgcatg
     1261 tgcttcttca tttaattctg taccgtacac cgtaaaccct ttgcctttca ttacagggat
     1321 tacatctgcc aaatcttttt gtaacacagg caaatgataa ttgcttccct gcatgcttcg
     1381 cagcaccttt gtactataaa tatctgccgt tcctttacct aataaaacac cagccatacc
     1441 aaacgcatct gccgtacgga tcatcgttcc cacatttcca ggatcctgta cattatctag
     1501 taaaagccag cctcctgaaa aatctggcgt atcttcagat gttaacgtca tcactgctaa
     1561 gatcccttgc ggtgtaggta gatctgacat agcggtcatg acctcatctg aaactagaaa
     1621 agtagaaatc tctttgttta cagccagcca gtctccccat tctttcatac ctctctgtgt
     1681 cacaaaaagt tcttttattt ctgcatcaga cgacgcagct tcttcgatca gatggaaccc
     1741 ttccaaaaga tattctgcct tttcttctct gtatttcttt ttatgtagtt tttttaattc
     1801 tttgattctt ggattttttg ctgattggat ctctttcaca ttccttcacc tcacctgatt
     1861 atatcatgga ataggtgctt gagcttgttt catcctaaaa aaatcggtat cattgattta
     1921 taaaacagga aagaaaggtg acgaacatgc gcaaagttaa aatgaatgtc caaggacgtg
     1981 tccagggcgt gggatttcgc tatatgacca agatggttgc tgatcagtta ggcgtgaccg
     2041 gaacggtaaa aaacgaagac gacggctcag tcacaatcga agcaatcgga aatgacgaca
     2101 tcatccaaaa atttatcgaa gaagtcaaga agtctccgag cccaagtgga cgagtgcagt
     2161 atgtggatgt ccaagaagat ccgatgattg aggaacgaaa gaaatttgat gtggtgggat
     2221 aaggttgtga aaaggtcgct tagttttgag tattaaggaa aattttgtga aaatggcttt
     2281 ccacattttt gcataaattt gacttaatac cgagaaactg acttttgaac accgtcgata
     2341 aggttgtttt tgaagcgctt tgcctcgagt attaaggaga aacattttca aaatagcttc
     2401 tcatattttg aaatgtaatg acttaatacc gagaggcagc tgataaaaca ccgtcaataa
     2461 ggttgtgaaa aagctggtct gcatcaagca ttaaggactg gttgtgaaaa agtcgcttag
     2521 ttttgagtat taaggaaaat tttgtgaaaa tggctttcca catttttgca taaatttgtc
     2581 ttaataccaa gaaactgact tttgaacacc gtcgataagg ttgtttttga ggcgctttgc
     2641 cccaagtatt aaagacaggt agtaaaaaag ctgatctatc acttgcagtg agttcatttg
     2701 actcctctat ttcgggcaga ataaaaaaag tttttagttt tttaaataag aaagaaacac
     2761 ttggaatcac tcttttcttt ccaagtattt ctttcttgat tttttgtctt ttttcaaaat
     2821 ttttcgctac gaaaaagaaa gaatatttat atgaaatttc tatgaagttg attgaattcc
     2881 atgcgctttt ttagtatagt taagtttgtg taaaaattat agaagaggaa gtattctatg
     2941 aataaatgga aaaactggtt attgggatcc ggacttgtca gtatcctgct ctttttatct
     3001 ggctgtgtgc ggatggattc aaacggaaac cctgacactt caggaatcgt ttatcgagta
     3061 ctcgtccatc ctatgggcca agcgattaca tatctagttg agaatttcaa ttggtcttac
     3121 ggctgggcag ttattgcaat gactgtgatc gtccgtatca tcatcttgcc actaggtatc
     3181 agtcaatcaa aaaaaacaat gatccaatct gaaaaaatgc aagcgttaaa accacaagtt
     3241 gaagcagcac aacaaaaact aaaagctgca acaacacgtg aagaacaaat ggcagcacaa
     3301 gcagaaatgc aacaagtata tcgcgaaaac ggattgagta tgaccggcgg aatcggctgt
     3361 ctgcctctat tgatccaaat gccgatcttc tctgccttgt attttacggc tcgctacaca
     3421 gaaggtatcc gtgaatcatc tttttacggc atcgatctag gctcaccaag tatggtgctt
     3481 gttgccattg caggggtcgc ttatctgctt caaggatata tttcaacaat cggtattcct
     3541 gaagaacaga aaaagacgat gcgtacgatg ctgatcgtct ctcctgctat gatcgttttc
     3601 atgtcgatca gtgcgccagc cggtgttaca ctttactggg tagtgggtgg tgtgttcagt
     3661 tgtctgcaaa cattcatcac aaacgttatg atgaaaccac gtttgaaagc acaagtggca
     3721 gaagagttga aacaaaatcc gccaaaacaa gtcgtcactc caagaaaaga cgtgacagaa
     3781 tcggcaaagc cagctgacaa taaacaacca aaaaacagta caaacaacaa aggccgcaac
     3841 gcaggaaagc agcaaaagcg gaaataaaaa tatatgacaa aaaactgtag acaaataaaa
     3901 aaatttcttt gttctacagt ttttttgtta caatcaaaga aaacgtcgct tttcgaggag
     3961 gaatgtataa tgatgtccaa ataatcaatg gatagtcgaa tggaagaagc caaaatttcg
     4021 ctagatgcac ttgttcctaa aaatcatttg gtccataaaa ttgacaaaat attgttattt
     4081 gattttattt atccaattgt tgaatcaact tactcgacca ttggtcgtcc tagcgttgat
     4141 cctgtcatct tagtaaaatt agtattcatt caatatttat ttaggattcg ttcgatgcgt
     4201 cagtccatta aagaagctga aacaaaccta gcttatcgtt ggtttcttgg gcttagttta
     4261 atcgataaaa ttcctcattt ttcaacgttt ggtaaaaact atgtacggca tttcagagaa
     4321 accgattgtt tgaacagata tttatcatta tccttgaaca agcagttgaa gctagattta
     4381 ttcatgaaga aattttgtat atggattcaa cctatattaa agcgaatgcg aaaaaacata
     4441 tttttacaag agaaatggta cataaataag ccattttata ccaaaaacaa ttgaaagaaa
     4501 aaattaatga agcaagaatt gcagaaggca aacgtccttt tggttcaatc attcatcagg
     4561 aggtggtaga agggaaaatt agtgtcgcag atccagaaag tggttattat gtaaaaacag
     4621 aacaagaaaa acagtttgct tattctgctc ataccgtttg tgatgaaaat ggttttgtat
     4681 tagatgtcat gattacgcct ggaaatctac atgacagccg aatgctcgtg ccacaaatcg
     4741 aacgtgttaa atcatgttgt ggtgtagctg ctgatgctgc gtacaaaaca ccttggaacg
     4801 ccaagtattt aatcgatcga aaactacgac ccatttttcc ttatactcga cccaaaagaa
     4861 gcaaagaacg ttttaaaaag aaagattttt attatgatcc ctattataac tggtacctat
     4921 gcccaaatga tcaaacactt cagtttcgca caactactcg agatggttat aaaaaatatg
     4981 tatctaaatc ttttatttgt gaaagttgtc tattattgaa aaattataca gaaagccaga
     5041 aacaccagaa agaaatacat cgacatattt aggaagacta cttagatgaa gcagaacatt
     5101 tacgccatac ggtgtacaat cgcgaaaaat ataaaaaaaa gaaaagaaac gattgaacgc
     5161 gtttttacag acgcaaagga aaagcatgga atgcgctaca ccaaatatcg aggcttggaa
     5221 aaaaccaggt gcatacgatg cttgtttttg ccgcaatgaa tctgcaaaaa ttagccattt
     5281 ggcagtgggg gcatatgtct tt
//
LOCUS       DAIGSZ010000114         5206 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.118, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000114 DAIGSZ010000000
VERSION     DAIGSZ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.118"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            33..1367
                     /locus_tag="NOB31_002733"
     CDS             33..1367
                     /locus_tag="NOB31_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974895.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1354..2988
                     /locus_tag="NOB31_002734"
     CDS             1354..2988
                     /locus_tag="NOB31_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974896.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3163..3996
                     /gene="msrA"
                     /locus_tag="NOB31_002735"
     CDS             3163..3996
                     /gene="msrA"
                     /locus_tag="NOB31_002735"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI0974897.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4109..5065
                     /locus_tag="NOB31_002736"
     CDS             4109..5065
                     /locus_tag="NOB31_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCI0974898.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1824 a          806 c          951 g         1625 t
ORIGIN      
        1 gtttttatta tggagaaaag ttttttaaaa agatagatgc tgctttttta tttagttgtt
       61 tatatacttt tgcaacttat cgaacagttg atatctatta tcgatccgca attgcagaag
      121 caatcgctct tacgattatc ccagctgttt tatattatgc ttatggattg atattcaata
      181 gagaaaaaaa agtcatcgct ttatctgtca gtataagtct acttgtgtat actcatgtct
      241 taactacact attgtgtagt gcattgattg cttgtatgat tatagttcgt ttgtttttaa
      301 gcaagcaaat aaaaaacgat ataaaatttg tggtcgtgaa tttagtaaag gctgtttttt
      361 tgacttgtgc attaactagc tatttttggt atcctatgtt gcagcagatg aattatcaag
      421 aaatacacag tcccttcaaa acagatttgc agctagaagc actttctatt tcagatagta
      481 tcattcaagc gttaaataac gatattacaa catacactat ggggttatta ggattggttg
      541 cgttgatttt tcctttattc atactgaaag aaatggagaa aaaagaaaaa atcatctatg
      601 ttggcgtagt ttctacatgg gtatgcgtaa ctaatttatt tccatggttt ttgtttcaaa
      661 aaacaccgat aagcttgctc cagtttcctt ggcgtatctt aggtatccaa atcttttttt
      721 cttcaatgat cataacgctt gtttttatga aaaagactat gaataaaaaa tattcatggt
      781 taatcattgg cgctactgtg gtgtttctac tcgtcacgtc tatagcagca aaagaaaatt
      841 acgcaaaagt tatccaatca aaacacggtc atattgttat caatgaagaa acactcccac
      901 gttatacaac atcagatatg ggaggattat acgattacgc cccaacagaa gcgataaaag
      961 aaaggcctca cttagaaaaa catgaagtaa aagtaggaga atcgtgggaa aaagggaagt
     1021 ataaagctgc agataataac attacttaca cagtggcaag caacaaaaag caaaaagtga
     1081 cagtaccagt atatgcttat ttaggtacac aggtaaaagt aaacggtaaa gtcgtaaatg
     1141 actcttataa aaaacatggc ttagtgaatg tggatgtaaa tgctggagaa aataagatag
     1201 aaattacaac aaaatatact ccaactgctc tcatggcttt atggatcagt attctgactt
     1261 attgtttagt ggtgtattca agttttaaac gatttgcacc taataagttg aaagattctc
     1321 gatatgtgac taaaaaggag ataaacaaga agaatgaaaa taaataaaaa agtagtaata
     1381 ttgagtggat taattatagt tagtagtata tattctttca tctttttcaa aaatacacag
     1441 agtatttata ccactggaga tctttctttt cacttatctc gaatcaaggg gttatcgact
     1501 atttttacca gtccgattaa ttatgagaca ttcaattata ctggatatgg tgtaaattat
     1561 ttttatccct ttctgacttt ttttccagct gtaatgttat attggatgac aaaaaatttg
     1621 attgtaagct atattattta cgtttggtta ttgaacttgt gtacaacact cgtagcttat
     1681 cattatggcg agcggttttt aaaacaaaaa aaagcggcat ttttatttag ttgtctctat
     1741 attttctctg cttatcggac agtagacatc tactatcgtt ccgcaattgc cgaagctatc
     1801 gcaataacac ttgttatccc tgtattattt tatgcttatc aaatcatctc tggaaaagaa
     1861 gaaaagtatc cgtctgtaaa gctagcattg agtatgagtt tgctagtgta cagccatgta
     1921 ctatcaacat taatgagtac agcattaatt atcattttta tttttattcg tttggtttct
     1981 aaaggtttca agaatgcaga ttttattgct atatttaaaa aattatttag tgcggcagga
     2041 atgacattgg ttctgacgag tgctttttgg tatccgatgt ttgaacaaat gctctaccaa
     2101 aaaatcaaca aacctagcgt gacaaattta tatgctcatg catctaatgt gttcgatagt
     2161 ctgactgaag ctatgaacaa cgacttaact acttactcaa tgggactagt tggtctgtta
     2221 tctttatgta ttcccctgat tttatttaaa aaattaacaa acatagaaaa aaagatttat
     2281 tatggtacgt gtttgacttg gctagctaca actagtttgg tgccatggta tcttctgcaa
     2341 aatacgccag ccaaattgtt acaatttcct tggcggatct taagcttgca aataatattc
     2401 tcttctctga tattaacgat gatatttttc aaaaatagaa gatacaataa gacaagagaa
     2461 ctattttatt tatttatgac tgttttgtta ttaatcactt taactgtttc tagtaaaaaa
     2521 aatttcaatc aaaaaataat ttctcagccg ggacatattg ttgtaaacaa agaaacagta
     2581 gaggcgtata ccactaaagg aatggattat tttttatatg attattctcc tatcgcttca
     2641 ttggagaata aggagcatat aataaaacac gaagcaaaga ttggcagtca atgggtaaac
     2701 cttccttata aaacaactgg tagttctatc atatatagag taactaatga gaagagccaa
     2761 gtaatcacac ttcctgtata tgcttattta ggaacgaatg tagaaataaa tcatcaacct
     2821 gtaaaggagc aggtgaatgc taatggattg gtacaaataa gcggagtcaa aggagttgct
     2881 gatattaaag taagcacaag ttatacagta acgactatta tttcttatct tgttacatta
     2941 actgcatatt tatgtttatt ttttaaaata gttttccata aaaggtaaat taacttttca
     3001 tttataaaat aaattgatta aaaaggagaa tctgtcgata aggattctct cttttttata
     3061 cgaaaaatct gtagggggat gaagtaatcg cttatttcct cactttatga taaattacag
     3121 ctaaagtcac tagcttgtct tcttcggaaa ggaggagaat ctatggatga ggaacaaata
     3181 ttcattcaaa cactttataa tctgattttg aatccgaata cacgagattg ggaacgaaaa
     3241 gtattgattc agacaaagaa tgacataaga gaaaatatat ccgttaaaga acagttatca
     3301 aaactagaag caacactacg tccattagct atccgaatga atctgacgcc tgatgtaatg
     3361 gacttttatt tattgattac ggaaggattt gataaggagc aaaaatatga cttttccaag
     3421 catgccatgc aagatgctga ctatcaagaa cgtgcagtat ttgcaggggg atgtttctgg
     3481 tgtatggtcg agccgtttga atcgaaaaaa gggatcctat ctgttttgtc aggatacacg
     3541 ggcggacatg ttgaaaaacc aaattatgat caagtaagtg gtggttacac aggtcatgtg
     3601 gaagctgtgg agatcattta tgacacaaga gaaataagtt atagcgagtt gctgacaatc
     3661 tattggcaaa ttactgatcc cacagataca tttggacaat ttcaagatag agggaagcaa
     3721 tatcgtccag tgatttttta tcaaggcgaa cgacaaaaag aattagcgga acaatcaaaa
     3781 cagaaactag acagttcagg aactttccac caaccaatcg tcacaaaaat cgaaccagcc
     3841 ggtacgtttt ggccagcaga aaactatcat cagcaatttt acaaaaaaca accgaaacgt
     3901 tataaaaaaa tccagcaagc acgtaatcaa tttctgatct atcaacgagt aaaaaacaaa
     3961 tggcaaaaaa atatacgaaa aaatcatttt gattaactcc ttttctttaa aatgtagtaa
     4021 actaaaaata gaaaaaagaa agcgttttaa aaagatttga tgaggaggag aaaaattgta
     4081 tattgcagat agtgcacgtt atgaaaaaat ggaatatcgt aaatccggtc attcaggttt
     4141 gaaattaccg attttatctc tcggattatg gcaaaatttt ggtgattatg atcctatcca
     4201 taatcaaaga gagattttaa gaggcgcatt cgacatggga attacccatt tcgaccttgc
     4261 gaataattat ggaggccctg ctggagctgc agagaaaaac tttgggcgta tttttagaga
     4321 agattttcaa gcctaccgtg atgaactgat tatttctagc aaagcaggtt atcatatgtg
     4381 ggaagggcca tatggggaat ggggctctcg taaatccatc atttcaagtt gtgaccaaag
     4441 tctccaaaga atggggctag attatgttga catcttctat catcatcgcc cagaccctga
     4501 tacacctttg gaagaaacag cagaagcttt gatgcaactt gtaagacaag gaaaagcatt
     4561 atatattggt atatccaact ataatggaga agatacaaaa aaaatgactg aaattttaaa
     4621 aagaaaggaa gcaccgttca ttattcatca gatgcgctac aatatgtttt ctcgtgcact
     4681 actagaagac gatctatctc cagtattaga agaagaaggg ctaggggcaa tcacgttcag
     4741 tccgcttgct caagggttgc tgacaaatcg ttatctacat ggtattcctg aagattctag
     4801 agcacatcgt aaggaaatac cattcctttc agaagaacaa gttggatcaa ctctggaaaa
     4861 aatcaaagca ctgcaaacaa tcgccgtatc acgaggacaa tcattagcgc aaatggccct
     4921 tgcatggaat ttgcgacaaa aatctgttac aagtgtactg gtcggagcaa gtcggttaag
     4981 tcagttacaa gaaagtgttc gaatgatgga taatttagat ttctcaccag aagaagaatt
     5041 gagaatcgac caaattctag aatagaaacg atgtaatcaa actttttatc catatattaa
     5101 aaaaaacaaa agatgacatc aagaatcgaa tgaagatcgt ctgttattga acatcatatt
     5161 ttttgtcgtt caaaataaaa atgatcgaag gctaggagtg aatttt
//
LOCUS       DAIGSZ010000115         5152 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.119, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000115 DAIGSZ010000000
VERSION     DAIGSZ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.119"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(52..561)
                     /locus_tag="NOB31_002737"
     CDS             complement(52..561)
                     /locus_tag="NOB31_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HCI0974899.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(673..1671)
                     /locus_tag="NOB31_002738"
     CDS             complement(673..1671)
                     /locus_tag="NOB31_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCI0974900.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1872..2456
                     /locus_tag="NOB31_002739"
     CDS             1872..2456
                     /locus_tag="NOB31_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCI0974901.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(2533..3726)
                     /locus_tag="NOB31_002740"
     CDS             complement(2533..3726)
                     /locus_tag="NOB31_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCI0974902.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            3790..4170
                     /locus_tag="NOB31_002741"
     CDS             3790..4170
                     /locus_tag="NOB31_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HCI0974903.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            4244..4606
                     /locus_tag="NOB31_002742"
     CDS             4244..4606
                     /locus_tag="NOB31_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974904.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEGNVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1683 a          891 c          959 g         1619 t
ORIGIN      
        1 aaaaaagaaa gaactcgtct aaatagacgt tttctttctt tttttgttga attattgagt
       61 aaggcgactt cttttttctg gttctttgtg tgctaatcga ctggcagcag cagcggcgat
      121 cgctccgacg atatcatcta agaaggtatg gacatgaacg ccatcgtggc tgtttagttc
      181 ttttaaaata ccaggtttca ccttgtcgat ataaccataa ttcgtaaagc cgatcgtacc
      241 gtaaacattc acgattgaca aggctaggat ctcatcgata ccgtaaaggc cttcgtcatc
      301 ttcgataata tgttgcaacg gactcatcaa ttttttcttt tctgctaata tatctaattg
      361 gattccagtg ataatggcgt tatgtacttc acgctttgtt agcacgctgt tgacactttc
      421 agtacaatcc gccaaagtca aatcagaaat atagtctttt tgtaaaaaca tgacaagttg
      481 tgcgatatct tctacagtta cgccacgttc cttcaatagt tctcttgcct tttcttctaa
      541 agtctcagtt ttgacgacca tattattgct ccccctttat tttttctttc tctatttcat
      601 gttaacggaa catgaaaaaa atgcaagaaa ctgctttcgg gtttaacttg aaatgcaaag
      661 agatataaaa aatcaactag gacgaagatt tttatcgtat aagcttgtgc tgtgaccagg
      721 ctgagttcgt tcctttggat taatatagtg taaagcgttg ttcactgcag taggtgcttc
      781 accgagccca gtagcaatca gtttcacttt tccttcatag gtacagatgt caccagctgc
      841 ataaacgcct ggaatagaag tagacatatc tgattttaca gtaatggcat ttctggtact
      901 atcaagtccc caagaagaaa gatgttctaa attagaagag aatccataat tgacgatcag
      961 agaatcaatc atcaaatcaa tcgtctcgtc acttttcact ttttttaacc ggatatctgt
     1021 cagttcccca ttattgcctg ataatccatc gatgagatag ggagtaagca agttgacaga
     1081 tgaagatttc aagcgtgata cactatgttc gtgcgcacga aattccgggc gacgatgaat
     1141 caagtaaact tcgcttgcaa taggctctaa catcaacgtc caatcgatag cagaatcacc
     1201 acctccagca atagcgactt tttttccagc atacttcatc aaatcattca cgaaataatc
     1261 caatccgtgg ttttcaaatg attcagcatt atctaaattc aattttcttg gctggaatga
     1321 accatttcct aaagctaaaa tgactgcttt ggaataatgg atgcctttat ttgtagtaat
     1381 ctcgataact tcgtcttcac gagtaagcga gagaacttct tcttttaaat ggaatgtatg
     1441 gttaaaagta gttaattgtt tttctaattg atcgattaat tcacttgctt ttattgctgg
     1501 atacccagga atatcgtaaa tatatttttc gggatacaaa gttgctaatt gaccaccaag
     1561 ttgaggtaga ctgtcaatga tttttgtttt agcttggcgc attcctgcgt aaaaagcggc
     1621 aaacatccct acaggacctg caccgatgat tgtaatgtca tagatttcca taaaaattcc
     1681 tcccttttca cactatagca gaatttaatt gagaatgctt ctcaaaaatg tttgaattcg
     1741 aaatcgaaac ggtaagttat agaatgtatc tagtgatgaa aaataaaaga aaacaaatct
     1801 agtattttta cgagaggtta ggtattatgt tattattatt atgaagtatg caaatattag
     1861 gaggaaacaa tatggcattc ccacaactag atttaaaaag tgaaaaagga ccaaaagctg
     1921 ttatcaaaac aaaccgtggt gacattactg ttcaattatt ccctgaacta gcaccgaaga
     1981 cggttcaaaa tttcattgaa ctttccaaaa aaggttatta tgatggcgtg atttttcacc
     2041 gcgttattcc tgatttcatg atccaaggcg gcgatccaac tggaacagga atgggtggcg
     2101 aaagtattta tggcgaaagt tttgaagatg aattcagtcg tgaactgttc aaccttcgcg
     2161 gagctttatc tatggcaaat tcaggtccaa acacaaacgg aagccaattc tttattgtaa
     2221 ataacacaaa tgtgccagct aatatgcttg gacaactaga aggtgctgga ttcccatcag
     2281 aaatcattga agcgtataaa ggtggcggaa ctccttggct agatttccga catacagtct
     2341 ttggacatgt actagaaggg atggacacag tagatgaaat cgcaaatgta caacgtggtc
     2401 cacaagaccg acctgtacat gatgtagtga ttgaaacaat tgaaatttca gaatagtttg
     2461 gtatggtacg gagtaattat gaaaaaggac gaaacctagt aaggtctcgt ccttttattt
     2521 tgaataaatg atttaatcga ttgtctctaa agcatacttg attcgattaa gtccttccag
     2581 taaagtttct tctggacaag caatattcaa gcgcatatgc ccatgaccgg aaggaccaaa
     2641 cgtgatgcca ggatttaata cgacttttcc tttccgaaca agagtgttct ccaattcttg
     2701 gtcgtctgaa atataggcgg taaaatctaa ccacattaag taagttcctt cagggttcat
     2761 tattctcact ttcggaagat actgttcaaa aaactgatta actgtttgaa catttttttc
     2821 tagataagga atcagttggc ttaaccattc tccacccgtc tcataagccg cttgggttcc
     2881 aatcagtcca aaagtgttga tttcgtgctg ttggttcatc actaaatgtt tttcaaaatc
     2941 agctttcatc tctggatttt tgataaatac cattgaattt ttgattgcag ctagattgaa
     3001 agtcttggtt gcggaagtaa aagcaactag tagatcatct aaattaggat caatcgttag
     3061 catggaagta aatgtatgat cgaataaagt taaatcttga tggatctcgt cactaaacag
     3121 aatcacttga tgttttaaac acaattcgct taactgtttc aattcttctt tgctccaaac
     3181 acgccctcca ggattgtgag gattgcataa aatcattgct tttacattgt tttcttcgat
     3241 ttttttctcc atgtcagaca agtccatgat gaaatgatta tttttttcta gcaaagagct
     3301 tcgaacgatg tgacgttgat ttgtttctat aatagaggaa aatggaggat aaactgggtc
     3361 atgaatcaaa atagaatcgc ctggttttgt aaaagtttgt actgctgcag ctaaactggt
     3421 taacacacca cttgtaaaaa cgatattttc tttcgtcaac tccacagcat ggtgttggcg
     3481 ttcccaatga atgatagcct gatatagttt atcagacaga gtggcataac caaagattcc
     3541 atgtttgatg tattcactaa acgctttagc taccccaccg ggagacaaga agtccatatc
     3601 tgctacccac aaaggaagta agtcatccat ttgatatgtc tcagcaattg cgtcccattt
     3661 tacactttct gtatcttttc ttgaaatctg tttatcaaat tcgatcatct taagacctcc
     3721 agtcattttc gtcgcttctt tttttgagct atttacagta taatgataaa tgcgaagaga
     3781 gggaagtaga tgacttataa aattggacaa ataattgaag gaaaagtgac agggatacag
     3841 ccttatggcg cattcgtttc tcttgataac gagacgcaag gacttattca tgtttcagaa
     3901 gtacaatccg gttatacgaa aaatatccat tcattgttaa aagtcggaca gccagtaaca
     3961 gttcagatca tcgacattga tgaatattcc aaaaaaatca gtttatcttt aagaacgtta
     4021 gaaaaaacaa atccagctgt tccatatcgc agaaaaaggt atttcacgaa taaaaatcgt
     4081 aagatcggat ttaccactat tgcggagcag ttacctattt ggatagaaga agcattatct
     4141 gaactagaac ggaaagaaaa taagaaataa aaagtgtatt ttttctgaaa atgtgctaga
     4201 atttttatgt aagccataga acaagttgat cgaggtggaa attttggcaa gcaaaagagt
     4261 tgctggtaca attatgttgc atttggagga tggtactaaa aaatttttgg tccattcaat
     4321 tgatgacaag ttggaatttg cgttagcgga actttctgaa ggaaagactg gtttagcgaa
     4381 tatacttaat ttcttaaaag aaatagttca tatcgatgtt agcaagatta gtttgatgga
     4441 attgacaaat acacatatta aagagggaaa tgttccgttg tttgtctttg aaactgaaca
     4501 aaagaatcaa agagaagaat taggcgaagg atatatttgg gaagaaccag gtcaaatgcg
     4561 ctctgttctt ggaacttacg aagtagaggg agtgcctttc ttctaaaata cagattaagc
     4621 gaacaaagaa gtttgaattt ttttcaaact tcttttttta ttgtttggtc caaaaaatac
     4681 aatgaaatgt tctgctaaag atagtttttt agtgcatttt attttcaaaa tatgttgaaa
     4741 acggttgtat aacgaataat aataattgat cgaaaaatca tttcacaaag taatgcttaa
     4801 tttatagttg accaaggaag aaatacatga taaatttaac agcgttgatt ctgaagtgga
     4861 tgttatatca catttctaaa aaatttaaaa aatagttatt gacatgttac taacgacatg
     4921 ataagataac tgagtcgtta aaaaagaacc acttgcgaag cttgattcta tcgaaaaaaa
     4981 cttcaaaaaa gttcttgaca aataacaaac gataagttat gataaatgag ttgctgaaag
     5041 atttcgaaaa acgaaatcga aaaaaacttt taaaaaagag ttgacaatcg cttgtctctc
     5101 tgatatgata taaaagttgc tacggcagcc aaaaacgaat cgggaaacac tc
//
LOCUS       DAIGSZ010000116         5088 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.120, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000116 DAIGSZ010000000
VERSION     DAIGSZ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.120"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="NOB31_002743"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="NOB31_002743"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HCI0974905.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="NOB31_002744"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="NOB31_002744"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HCI0974906.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="NOB31_002745"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="NOB31_002745"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HCI0974907.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="NOB31_002746"
     CDS             complement(4028..5044)
                     /locus_tag="NOB31_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCI0974908.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
BASE COUNT         1337 a         1271 c          909 g         1571 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaac
//
LOCUS       DAIGSZ010000117         5043 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.121, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000117 DAIGSZ010000000
VERSION     DAIGSZ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5043
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.121"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(128..1936)
                     /gene="pepF"
                     /locus_tag="NOB31_002747"
     CDS             complement(128..1936)
                     /gene="pepF"
                     /locus_tag="NOB31_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HCI0974909.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2112..3110)
                     /locus_tag="NOB31_002748"
     CDS             complement(2112..3110)
                     /locus_tag="NOB31_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HCI0974910.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3336..3989)
                     /locus_tag="NOB31_002749"
     CDS             complement(3336..3989)
                     /locus_tag="NOB31_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HCI0974911.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4321..4719)
                     /gene="spxA"
                     /locus_tag="NOB31_002750"
     CDS             complement(4321..4719)
                     /gene="spxA"
                     /locus_tag="NOB31_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCI0974912.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1503 a         1039 c          771 g         1730 t
ORIGIN      
        1 aaaaagatgt tggtgaagtt caccaacatc aaaaagtata gagccttaaa aaaatacgtc
       61 gactccctta caagagagcc gacgtatttt tttcgtttct attcgagaaa atcaaaaata
      121 gaaagcctta taaacgatcg atcaattctt ctaattcatt tagacgttgt tcaaacatcg
      181 acattgcatc ttcaatatat gcagcctgtg tcatatcaac tcctgctttt ttcattactt
      241 ccacaggata atcgctgtta cctgctttta ggtaagccaa gtagttctct agtgcctctg
      301 gttcctggtt tagtattttc ttcgccagtg ctgaagcagc agaaaagcca gtcgagtatt
      361 ggaaaacata gtaattataa taaaaatgcg gtatccgtga ccattcgaat ttaatttctg
      421 ggtcttcttc gactgctgga ccataatatt ttgcattcaa tttaccataa ctatcactta
      481 ggtattcact agtcaatggc acaccttttt catcttccgt atgcatgaaa tgctcgaatt
      541 cagcgaattg tgtctggcgg aaaactgttc ctttaaaccc atccaagtaa tggttgagta
      601 cataagcccg tacacgaggg tctttttctg tttccaataa atactccgtt aggatatttt
      661 cattcgttgt cgaagcaatt tctgctaaaa agatggagta gtcgccgtac acataaggct
      721 ggttcgaacg agtgaaataa ctatgaacac tatgtcccat ttcgtggaca agcgtaaata
      781 gctgatccag cgtatcatgc caattcaata aaatatatgg atttgtgtca tagcttcccg
      841 aagaataagc accgcttcgt ttccctttat tttcgacaac atcgatccaa cgttcagaga
      901 atgctttttc tacgatggcc atgtattctt cacccattgg tttcagtgct tctaaagctt
      961 tttcttttgc ttcttcgtac gtaaaggtaa ttggagcttc ccctaagacc ggtgtataaa
     1021 gatcatacat gtgcagtttt tccacttcta ataaacgttt ccgtaattcc atgtatcgat
     1081 gtaacaaagg caaatgcttg tttaccacgt ctaccaaagt atcgtataca ctttcaggaa
     1141 tatgattatt gctcaaagac gcttctctgg cagagctgta attacggact ttcgctttaa
     1201 aattatgtcc ttttatatgt gtgcctaaag tagaagcaaa tgtatttcta aattgttcgt
     1261 aaacactgta caacccctta aatgctgctt cgcgcaccct tcgatccgtg ctttctagca
     1321 actgaccata cacgccatga gataattgga ctatttcacc attttctcct tcaatcgttg
     1381 gaaaaactag atctgcatta ttcaaaacag caaatgtatc acttgaagca tcaaagattt
     1441 cacctgctcc agcaagaaga gattcctgct cagcagataa gacatgggct cgattatcta
     1501 ctatttgctg gatataatgg cgatagactt ccaattttgg ttcttctttg aaatattgcc
     1561 aaatctggtc atctgacaat tgcaatattt ctggttcaaa ccaggaaacg gcttcactaa
     1621 ctttcgaaaa cagactgctt gctcttgcat aaagcgcttg gtaatctgta tttccagtgt
     1681 cttgatcgtt tttaaggtgc gcatatacat aaatgacttc agtttggcga taaaccctca
     1741 atacgaattc aatcgcattt aaaaattgag aagcgccttg atcaagtgtt cctttgtgtt
     1801 tttcagattg ttttaactct tctgataatt ccaaatattt ctcatcaaac tcttggtcgc
     1861 ttgaaaagat cttggtcaag tcccaagtta aattttcagg caattcttct cgttttggca
     1921 actgctttac ttccatgaaa tccactcctt ttcttccctt agctctatct atcaaaatag
     1981 atcatagtct aacatccaca tgtcacagca tctaactttt ctactcattc atgtgtctgc
     2041 ttccatcaat tttagcataa ctaaatcttg ttttacatag aaaaccgatt cctagcctat
     2101 ttttatactt actatttttt caaagaagac aagtgtatgc attcgttaaa aaactgctga
     2161 tagaccatct cttcatcaat cataggaaaa agccattccc ttttatgttc ttttatttgg
     2221 caaagccatg agttgaaatc aggaactttc tggttttcca aggcttcttc gtacaacatt
     2281 cgataaagaa aaacctgttc ttgtaaataa aagaaaaacc gacttttttg atagatccac
     2341 gatgatagat gcaaaagatg tttatgacgc aagtagcatt gttcttgtat ggatactgta
     2401 ttcttttgct tgtgaataag ttggcgtgtc agccatttct tcccatcttc actcactttt
     2461 tctatttttt tcatttggtt cattttaatt tcgttactag tgaatatttc tttaaggtcc
     2521 ctactagaaa aagtccagca gctactgcaa aaggaaatat gccctgatac agtctctgta
     2581 atatgatgat acaaataaag cttttgtttc ttgagatcag ctttccagca atgcactcct
     2641 ctttttctat tatagtagca gcaacttttt tctatcaatg agaattgcga ttgtccaaga
     2701 aaagaattac caagtatcca ccatacttgg taactgttat tcaaataatt ttgggttctt
     2761 tcaataaatc tctggtgaga cagtctagaa cattggattt ctattgctag attcgccaac
     2821 aaaatatccg gcctttgccg caacctcggc aaataggctt ccaaaaatac tggttctact
     2881 gactgtccca gccaatccat gaagcattcc tttaactgta agtgctcttt tgattctctt
     2941 tcactaaaga ccgaacagtt atctgatttt tgatgggcaa aatgagcaca ttttttcttt
     3001 ccctttttca aaatcactct ttttcgacag ccacgacaat aatatttctt tcctttttct
     3061 gcatgtttag caaaacagca cttattatat tcattcattg caagcagcat ttttctccct
     3121 ctgaacttat ttacgtctaa gaatttattt acacgaaaaa agagggcgtg aaaaagctat
     3181 tctgcatcaa gtaataagaa cagctaaaca aaaatagttc ccaatatttt tcgtttggtt
     3241 gggcttgtta ccgcagatgc aagcttttga acacatttat acgaaaaaaa gactgcgaca
     3301 caatttttgt cacagtctct tactataatg ctgatttata caaaataaaa tttcgttcgc
     3361 tcgatagcat tacgcgccat cagacattgt ccatattcat tcaatgtttc tggtgtacga
     3421 tcgctctttt cagcaaactc caaaattcga gcaatctgat tctctacatc cgcttggttg
     3481 agattttcca tccagaagtg aacgactagg taatagcgct cttcgaataa atacaaatca
     3541 gtccaagcag actctagttc gacatctgtt gcaagttgga tcacttgttc aaaatcttca
     3601 aaagcaaaag ttgcttgtct ttcctgttct tctagggcgc ttccagataa ttcttcctcc
     3661 ggatcgctgc caataatctg ctgacgaaga aagtcactca catcttctga atcaacagta
     3721 gaatcttctg attgagaaat ttcttcatcc ggaagatttt tactgataaa cagttctaat
     3781 ccgtctcctt ttggcaaaac ttggaaagtg acagcttcgc ttcctcggaa ctcctcttcg
     3841 atatcaactt cttccaaaat actataaaag aaattttcga tttctttgtg attgccaagt
     3901 aaatccaaaa atgaaacgcc ccgttcctct aaatcttcat gaccaattag tacacggatc
     3961 gtattttcat taatatgttc catttccatt ttgctacacc tcactttgcc acaatgttta
     4021 atatagattc attgtagcga aatcagctta aatgtaaaga aaaaaaatct cgctgttaag
     4081 cgaatttaat aaaaccagcg gatttttcaa cctttcaagc tatcttattt aactataaca
     4141 tttttggcag acgaatacta tatagccgac ttttcagcta attttccctc tctatttttc
     4201 gtgcaatcat catcttctac taccttttta tacatctaat caagaatact ttttgtaaaa
     4261 acaaaaaaac ttggaaaaac tatctttgta atagtctttt ccaagtttcg tattatcctt
     4321 ctataatcca gccatcaatt gtgcttgacg taattctaat tgtcgtacat cgcgcggtag
     4381 gaaccgacga atttcatctt cattaaaacc aacttgcaga cgtttatcat caatcatgat
     4441 tggacggcga agcaatccag gattgttttg cacaagttcc aataattctt gtaacggcag
     4501 atcatctaaa tccatgttca gtttttggaa tactttggaa cgtgtcgaga tgatttcttc
     4561 tgttccgtct tctgtcattt gtaaaatcgc ttttaattca gaactgttca atggttctga
     4621 aaaaatatta cgttcaacaa atggaatctg atgttcttgc aaccacgcac gagcctttct
     4681 gcaggaagta caacttgggg aagtatataa tgttaacaac gtgcaccact ccttttcgtg
     4741 ataagaatca cttttttgta acagaagatc ataataatct cccatctgtt tctattatac
     4801 ataatcaact tttaaatagc tacctttttt tcataatttt tttaaaaaaa tgaaagttat
     4861 ctaaggttaa tatacagtaa aaccagcatt ctcgcttttt ttatcattta aaaattagag
     4921 ttttcaaatc taattcaaat tttctaaaca tatgaaacag cgtataaaac tgtactatta
     4981 ttttatctca aaagctaaat gaaaccgatt tcttaagatt ttttatgttt tttatttctt
     5041 taa
//
LOCUS       DAIGSZ010000118         5023 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.122, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000118 DAIGSZ010000000
VERSION     DAIGSZ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5023
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.122"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            282..521
                     /locus_tag="NOB31_002751"
     CDS             282..521
                     /locus_tag="NOB31_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974913.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(883..1143)
                     /locus_tag="NOB31_002752"
     CDS             complement(883..1143)
                     /locus_tag="NOB31_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974914.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1328..1825)
                     /locus_tag="NOB31_002753"
     CDS             complement(1328..1825)
                     /locus_tag="NOB31_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HCI0974915.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1955..2665)
                     /gene="budA"
                     /locus_tag="NOB31_002754"
     CDS             complement(1955..2665)
                     /gene="budA"
                     /locus_tag="NOB31_002754"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HCI0974916.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="NOB31_002755"
     CDS             complement(2678..4342)
                     /gene="alsS"
                     /locus_tag="NOB31_002755"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HCI0974917.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4547..5014)
                     /locus_tag="NOB31_002756"
     CDS             complement(4547..5014)
                     /locus_tag="NOB31_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974918.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
BASE COUNT         1528 a         1043 c          770 g         1682 t
ORIGIN      
        1 tatcctccta gcaactattt aaatacccaa aaaaattacc tctagataat atcataccta
       61 cgttttcact tataaatttt ttcataaaaa aagcgtttag aggcataatc gttaatacag
      121 atggtaacca atgtatctgg tttgaactgg gatatcaccc tctccatata tgtattacta
      181 agactaatag atactataaa agacttgata gttttgcatt gattttgcct aatactgagc
      241 ataggtgtat gctaaacgat actataagga gtgtgtacat aatgaaaaga attctgttta
      301 tcagtttatc aaatttattg ttacttactg cttgtgggac ttctgcatca aagaacatac
      361 cttcagatac gcaaatttcg aatagtatcg attcaacaat ttctacaaat gagaaaaatt
      421 ctccggtaga aacttccgat ataaaagttt ctacctctgc aaaaaacagg gtaaagaaac
      481 tgtcagcacg tctcctttat ttcaaacaaa ctctgaatta gcttcttcat cttcttcagc
      541 aaataatgat gatagtttcg cgtttactcc taactaaatg caacctttac aaatgcttta
      601 cgataacaag cctgagctaa atcatcctga tatcagtttt gcattttttg aaatgattgg
      661 atcggatgat ctttttaaaa ctactagttt gtctatccga aaataggaca gttctggcag
      721 tataggtttt tatcgagttt ctccaccagg cctcgttaca gagacagatt ctctaggcga
      781 accttttgaa taaatcaaaa atcatgaaca atcactgcca actaaataaa gtgccttcaa
      841 aagcttggtc ttctcgcttt tgaaggcact ttatttaaat ctttatgaaa ctaaagtatg
      901 ttcatatttg ttgctatagt tatatagata ttctgttgtt tccaactcat aaacgtgagt
      961 atattttgcc actacttttc cgcatttttc taatatttca ttgcgatcga cgtcatgata
     1021 ttcgtctacg cagatcacaa cacaattttc taatttactg attacttctc caaccacttt
     1081 ttgtttcaag ccaataggtt ggcaaatata tttttttcct aaaatgatag tttcgttatt
     1141 catatttcat ccatccttaa tgtttttcca ttatttaaaa tgataatacc attaaaatat
     1201 gattatgaaa atcaataaca cttgtgattt tataaaaaaa taaaaaaacc gaaaaacaga
     1261 aatgcccact gtctttccgg ctctttttat tcttgatttc tcttcttttt tgtttcaata
     1321 gacgatttta gttattaata aatgaaaaag catttatatt aaaatttgct aataaaagat
     1381 ctacatattt ttctagaaat gcttgatcga tttcatcata ccctttcgtt actccgcaat
     1441 cgatatctaa aacaccgatt aaattacctt cttttaccat tggcactacg atttctgatt
     1501 gtgcggctga atcgcaggaa atgtaatttg catgggtttt gacatcatca acgatcaatg
     1561 tttcttgttt ttcagctgat tctccacaaa ctccttttcc catcttgata cgtgtgcaag
     1621 aaactcgccc ttggaacggt cctaaaatca attcattacc atcgaataaa taatatcctg
     1681 caaagacagt ctcaggcaaa gtctcattca acaatgcaga tgaatttgct aaatttgcta
     1741 accagttatc ttctgcttct aataatcctt gttgctgtaa taataaaatt tcgtatgcat
     1801 cttttttctg tttttctgtc cacatgataa aaaccgctcc tttttgatct atggagaaga
     1861 ttatagctca gtttttttgt aaacgctagg tttcctcctc aaaaaaacga gatacgtcag
     1921 gttaatcacc ttgaacgcat ctcgctgtct ttttctattc tgcttgttgg atttctgctg
     1981 ctaaatcagc ataatcaatc gtttcgtgaa caaaagtcgg atcatcaact ggaaaatgct
     2041 gtacaaggga cgagatgcgg ctaatctcaa cttttccttc agccacttca aaatccatta
     2101 catgtccgcc aaatgtatgt gtatcatcga taaaatgcaa gtgaaatccc gctgcagcaa
     2161 ctccttggaa taattcaggc gtaaagaacc cgactaatgt tccttggaca ttgctttgtt
     2221 ggaattctgg ttgagactct gaaatttttg ctagtcttct gtaaggtttt tcttgcttcg
     2281 gcatgatacg gatgtgcata tttttgaata atccagttat cttcactgcc aaaaataggt
     2341 tttccccggc ttctcttact aatatgtctt ttttcaattg ttctccatct gcagtttttg
     2401 agacagaaaa actagtatct ggcgtaaaat ctgtaattgc tgcatagggg gtaagttcac
     2461 ttccatctaa ttgggcaact gagccatctg atcttccttg ataagctacg ccatctaaaa
     2521 agatgacttc accatcaagc ccatgcaatg ttcccaatcc cagagttcct ttttctaata
     2581 tatgagcaat cgtttctgtt ccatccatca agccagccat caaagctcct aatgtcccgt
     2641 gctggtataa gattttttca gtcatgtcga cacttcctta atagaattga tctggtaaga
     2701 ttgtttctcc caatttctca ttatcacggt aatcaatcgg aatatcaata attacgggtc
     2761 cttctgtcgc aaatccttct tctaaagctt tttctaattc ctctacactt gtagctcgga
     2821 ttcctttagc gccaaaagct tctgcatatt tcacaaaatc aactggacca aagtctacac
     2881 ctgacgcccg ctgatatttc attttttctt ggaactctac catattgtag tgtccatcat
     2941 tccaaatcaa atgaacgata ttcaattttt tacgtaccgc cgtttctaaa tcctgggcag
     3001 agaataaaaa tcccccatcg ccggaaactg atacgatttg tgtatttgga cgcaccaatg
     3061 cagcagaaat cgcccatggc aatgcaacac caagcgtttg cataccatta ctgaataaca
     3121 aatgacgagg ttcataactt ctaaagtggc gtgccatcca aatataatga ctacctacat
     3181 ctacggtaac agtcatatca tctgttactt ttgactgaag cgtgttaata acttctaaag
     3241 gatgcaagat acctgcttct ccttttgatt gaacaatgtc ccgctccgtt aattctgctt
     3301 gaagagatgc taaatattct tttgcatctt ctgacacttg ttgaggctct aatgaacctg
     3361 tcaataaatc aagagtggct gagatatcac cgatcaattc tctttcaggc tgcataaaag
     3421 gatcgatttc agctggcgct tcatcgatca caatgatccg cgcatctttt tccgcattcc
     3481 agtttcttgc ttcatattcg attggatcat agccaatagc aataactaga tcacttcgtt
     3541 tcaaaagcat atctcctggt tggtttctaa ataaacccac acgaccaaag aaatgcgctt
     3601 ctaattcacg tgagatcact ccagctgctt ggaatgtctc tacaacaggc aatgctgtct
     3661 ttccaactaa ttgcctgatg gctaacgttt ctttttcact tgatcctcgc atacctacta
     3721 atagtaccgg tagttttgct tctctaatgc gttcagctag gtaacggata tcatctgcag
     3781 aagcagaacc taatttagga tcgctcaatg gcttgatgac attcccttgg acaggtgcat
     3841 ccactacatc ttgcgggata ctgataaagc tcgcgccttt ttttgaactc ttagccatac
     3901 gataagcatt ggcaatcact tctgaaattg tttctggatc ttggatttct gcactgtatt
     3961 ttgtgattgg ctggaacagt gctgcattat ccatgctttg atgggtcaac ttcaatagat
     4021 cgcttcgttt tacttgtccg gcaattgcta aaactgggtc accttctgct gtcgctgtta
     4081 ccaaacctgt agctaagtta ctagcaccag gaccacttgt tgcgataact actcctggct
     4141 ctcctgtaat acgtccgatt gcttgtgcca taaatgcagc attttgttcg tgacgagtca
     4201 cgattaattc aggaccttga tcctctaatt cattaaatac accatcgatt tttgcacctg
     4261 gtataccgaa tacataatca acatgatgat taatcaaact ttctactaca gatttcgaac
     4321 cttgtttcat tttttcgtcc attgaacatc gtccttttta tgctttattt ttaattatta
     4381 gttagaaata atcacaaata attgatacag tttctaaacc tgtttcattc aaaagtatag
     4441 cacgttttat ttcatttgtt tagccatatg tttcaaaaaa tgaaaaagaa tgacagtttt
     4501 tacataaaaa ctgtcattct taattgaaag tttcaattta taaagtctac agatccatag
     4561 ttctcatcaa tttacgattg ttgaagtaaa tcaaaccaaa tacgatagaa ggacctagta
     4621 gaatacacca ttggggcttt acgaaaaaga agagaaacaa acttgtcaat agtaaaaaat
     4681 ctagtaaact cacataccat tttttcaacg tatagtagaa cgctatccgt agaacttgat
     4741 ttggtttcga cgctggattt ctcacctgaa aataccagta gttgatgcta aaggaaactg
     4801 ataaacaagc aagtaaaaca aacaacggaa tcaaccattt tccataagaa aaacgtataa
     4861 aaaagaaaca atcaaaaatc attatcacac taactatcca agcaaatagc caataaaaaa
     4921 atccctttag ccaaaattgg cgaaacgtct ttatgaacaa acgtactggt gaaaaacttt
     4981 tttcttttgc taattcttct gtcataccta tcatcacgat gca
//
LOCUS       DAIGSZ010000119         4923 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.123, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000119 DAIGSZ010000000
VERSION     DAIGSZ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4923
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.123"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            83..970
                     /locus_tag="NOB31_002757"
     CDS             83..970
                     /locus_tag="NOB31_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCI0974919.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="NOB31_002758"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="NOB31_002758"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HCI0974920.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="NOB31_002759"
     CDS             2272..2718
                     /locus_tag="NOB31_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCI0974921.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="NOB31_002760"
     CDS             2991..4343
                     /locus_tag="NOB31_002760"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HCI0974922.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="NOB31_002761"
     CDS             4514..4801
                     /locus_tag="NOB31_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974923.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1693 a          812 c         1030 g         1388 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 ccc
//
LOCUS       DAIGSZ010000120         4915 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.124, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000120 DAIGSZ010000000
VERSION     DAIGSZ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.124"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            427..1248
                     /locus_tag="NOB31_002762"
     CDS             427..1248
                     /locus_tag="NOB31_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0974924.1"
                     /translation="MYQFLKTGATILNYYQQYKENKKRCGRRSIALPEEQKEYVQKRV
                     VQGWTPDVIVGRSEMKLDCSVRTLYRMFQTGAFNVRDLPMKGKRKPNGHQEKRGKQAF
                     RRSIHERIKEHPEFENEFGHLEGDTIVGRKHKSAVITLVERLSKVIITLKPAGRQAMD
                     IENRINHWFQTVPKHLFKSITFDCGKEFSNWKAMGNQNDIDIYFADPGTPSQRALNEH
                     SNGLLRRDGLVKAMDFNEVSESFIEYRKHFLYSILSSFKFSIDYIYCEFCRGSET"
     gene            1335..1940
                     /locus_tag="NOB31_002763"
     CDS             1335..1940
                     /locus_tag="NOB31_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HCI0974925.1"
                     /translation="MILENKLGLTNQVELAKAEEKLSKQKAKELYDSGKINEIEVGTF
                     KGLSEIHDFLFSEIYDFAGKIRTVNIAKGNFRFAPVMYLEQSLNHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1956..2531
                     /locus_tag="NOB31_002764"
     CDS             1956..2531
                     /locus_tag="NOB31_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0974926.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMDRDMIVERTQEGKLFAKKNNPNFKEGRPKATITPKKRHAYELI
                     TSGKSYKEVEAITGFSRSTLFRIKKQIEASE"
     gene            2691..2894
                     /locus_tag="NOB31_002765"
     CDS             2691..2894
                     /locus_tag="NOB31_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HCI0974927.1"
                     /translation="MKEQQLGYTLWGRPLYGLERRTAVSIDCACGELIQLNIQTKQYN
                     CKNCGNCYQFIDQDFQLLNEKNK"
     gene            3003..4328
                     /locus_tag="NOB31_002766"
     CDS             3003..4328
                     /locus_tag="NOB31_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCI0974928.1"
                     /translation="MLDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKNLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYQNVPDKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIKDLANWNPYTIKSRLGVIGLQLYFHANGIDRTDIAIAPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHHCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTRELQDYCLFLFNKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDDEK
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            4321..4671
                     /locus_tag="NOB31_002767"
     CDS             4321..4671
                     /locus_tag="NOB31_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974929.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRANQNLAKEQMRTE
                     EIAEILNASVIKNRSVCIQKEERNAEGYYPDDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            4668..4847
                     /locus_tag="NOB31_002768"
     CDS             4668..4847
                     /locus_tag="NOB31_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974930.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLFI"
BASE COUNT         1712 a          790 c         1011 g         1402 t
ORIGIN      
        1 aaataaagta gtaaattaat cataatcttt tcaacaacag gaatagtcaa gttagactgt
       61 tcctgttgtt tctttatttt ccttatcatc ttcaactttt tcaaatactg caaatacaaa
      121 atatcaatat aacttattcg ttctatcaat cagttcctaa tatctactca tcaaaatgaa
      181 atttcaaact aatctcatca tagtattctt ttcgtcgatt gtaaaattaa gctagacaac
      241 taaaaagatc atttgtgcta cactcaaaat agttccgacc aaagaattat taaggagtga
      301 gtacaaatga cctacaccca tcttacaaca gacgaactgg taatcataga gtcttatttc
      361 aaaaataatc aatccgttgc caaaactgcg caatgcttag gacgtgcgtg acaaacgatt
      421 cataacgtgt atcaattttt gaaaactggt gctacgatac tgaactacta tcaacaatac
      481 aaagaaaaca aaaaacgctg cggtagacgc tcgattgctt taccagagga acaaaaagaa
      541 tatgttcaaa agagggttgt tcaagggtgg acaccggatg tgattgtcgg ccgctcggaa
      601 atgaaacttg attgttcagt ccgtacactg tatcgaatgt ttcaaactgg cgcatttaat
      661 gtgcgtgatt tgcctatgaa aggcaaacga aaaccaaatg gacaccaaga aaaacgtggg
      721 aaacaagctt ttcggcgcag tatacatgag cgcatcaagg agcatccaga atttgaaaac
      781 gagtttggcc atcttgaagg agacactatt gtcggtcgaa aacacaaaag tgctgttatt
      841 acattggtgg aacgtttgtc aaaagtgatt attacattga agccagccgg tagacaggca
      901 atggacattg aaaatcgaat taatcattgg tttcaaacgg ttcctaaaca tctgtttaaa
      961 tcaattacgt ttgactgtgg gaaagaattt tcaaattgga aagctatggg aaatcaaaat
     1021 gatattgata tttattttgc ggatccaggc accccgtcac aacgcgctct aaatgaacat
     1081 tcaaatggat tattacgtcg tgatggatta gttaaagcca tggacttcaa tgaagtatca
     1141 gaatcattta tagagtacag aaaacatttt ctgtactcta ttttgtcttc ttttaaattt
     1201 tcaatagatt atatctattg tgaattttgt agagggtcag aaacttaata gtttttgaca
     1261 catggttaaa ttcgcgatac aataggattt gtagtgtttc ataaacttat gtcaaaaagt
     1321 taaggggatt ttccatgatt ttagaaaata aattgggttt aacgaatcag gttgagttgg
     1381 ccaaggctga agaaaaactc agtaagcaaa aagcaaaaga attatatgat tctggaaaaa
     1441 taaatgaaat cgaagtcggc acgtttaaag gcttgtctga aattcatgat tttctctttt
     1501 cagaaattta tgattttgca ggaaaaattc ggacagttaa tattgcaaaa ggaaattttc
     1561 gttttgcgcc ggtcatgtac ctagaacaat ctttaaatca tattgatcag atgccgcaaa
     1621 cttctttcga agagattatt aagaaatacg tggaaatgaa tatcgctcac ccttttcgcg
     1681 aaggaaacgg gcgcagtact agaatttggc tggatctcat tttaaaggaa gaattgcaaa
     1741 aagtggtcga ttggaacttg atcgataaag cagactatct ttctgcaatg gagcgcagtc
     1801 caataaatga cttggaaata cgctatctca tttccaatgc cctgactgat aaaattgacg
     1861 atcgtgagtt atatatgaaa ggaatcgatg tcagctactt ctatgaagga tactctgagt
     1921 atacgataga tgatttgtaa aagcaggtga gttaaatgac aaaatatggc tatgcacgtg
     1981 tctcaaccgc ttctcaaagt acaaaggaac agatacaaca gctacttgag aacggtgttg
     2041 agaagaagaa tattttttct gaaaaattta caggtacgaa acgagatcgg ccaaagttta
     2101 atcagctgtt ggctggtctg aagcctggag acgaaatcgt tgttacgaaa cttgatcgat
     2161 tcgcccgtaa tacaagagaa gcactagaga tcattgaacc tttactcgat gataacgtca
     2221 cgattaaggt attgaatcta gggacgatcg aaaatacatc gatgggtcga atggttacac
     2281 gtacgttgtt gagtgtagct gaaatggacc gtgatatgat tgtagaacgt actcaggaag
     2341 ggaaattatt tgcgaaaaag aataatccta attttaaaga gggacgtccg aaagcaacaa
     2401 tcacaccaaa gaagaggcat gcatatgaat tgattacttc cggcaaatcg tataaagaag
     2461 tggaagccat aacgggtttc agtcgtagta cactttttag aattaagaaa caaatagaag
     2521 cgagtgagta gaagattgat aaaattaata taaaaatctc ttttaaatca aataaatcgt
     2581 tgtttatacg agcattctaa ggtcaggttc actcattaag atgtatcatt ggtcgaacga
     2641 agcgtcatac cagctacgaa tagacatatt tttagggagg aacgaagtaa atgaaagaac
     2701 aacaattagg ctacactctt tggggacgtc cattatacgg attagaacga agaacggctg
     2761 tatcgattga ctgtgcttgt ggtgagttga ttcaactcaa tattcaaacg aaacaataca
     2821 attgtaaaaa ttgtgggaat tgttaccaat tcattgatca agacttccaa ttgctaaacg
     2881 aaaaaaacaa ataggtttat tatagtcaga caattgtctg gctatttttc tatttagaga
     2941 agatcctcgt tgcaaacacg aacgtatgtt tgtataatat gagagaagag ggggagaact
     3001 ttatgcttga ttactcaaaa gagccagtca atgactactt tctaatcgat atgaaaagtt
     3061 tttacgcaag tgtcgaatgt atagaaagaa atttagatcc attaacgact gaattagttg
     3121 tcatgagtcg agcggataat acaggatcag ggttgatttt agcttcttca ccagctgcaa
     3181 agaagaaata tggtatttct aatgtcagca gaccacggga tctaccacag cctttcccta
     3241 aaacattaca tgttgttcca ccacgtatga acctttatat taagcgtaat atgcaggtaa
     3301 ataatatttt cagaagatat gtggctgatg aagatctact gatttactcg atcgatgaat
     3361 caatcttaaa agtgacccga tcactgaatc tttttacgac tgaaggaaca cgaagtcagc
     3421 gaaggaagaa tctcgctcaa atgatccaag aacgtattaa agaagagcta ggattgattg
     3481 ctacagtagg tgttggcgat aatcctcttt tggctaaact agccttagac aatgaagcga
     3541 agcataatga aggatttatt gccgaatgga cgtatcaaaa tgttcctgat aaagtatgga
     3601 atattcctga aatgacagac ttttggggta ttggttctcg aatgaaaaaa aggctcaacc
     3661 aaatggggat catgagtatc aaagatttag ctaattggaa tccatacacc attaagagcc
     3721 gtttaggtgt gattgggtta cagctgtact tccatgcaaa tggtattgat cgaactgaca
     3781 tagcaatcgc accagaaccg acaaaggaaa aatcatatgg caattcacaa gtgctaccac
     3841 gagattatac tagaagaaat gaaatcgaac tggtcgtaaa agaaatggct gagcaagtag
     3901 caatccgtat taggcaacac cactgtaaaa caggttgtgt tcatttacac attggaacgt
     3961 cgattttaga aacgagacca gggttttcac accagatgaa gatacctatc acagataata
     4021 caagagagct acaagactat tgtctgttct tatttaataa atactatgag ggacaagaag
     4081 tccgccatgt cggaatcact tacagcaagc tagtttatac tgattcgctt cagctggatt
     4141 tgtttagtga tccacaaaaa cagattgatg acgaaaaact agacaaaata atagataaaa
     4201 ttaggcagaa gtatggtttt acgtcaattg tacatgcttc ttcgatgtta gaaggcgctc
     4261 gtagtattac tagaagcacg ttggttggtg gccatgcagg cggcgcaggg gggcttaaaa
     4321 atgattgact ataacgatcg aggacgattg aaatgggcag gtttctattt atcggatcat
     4381 actgaagaga tcgatgcaga taatgagcaa cgtgcaaatc aaaatttagc aaaggaacaa
     4441 atgaggactg aagagattgc ggaaatattg aacgcttcag tcataaaaaa tagatcagta
     4501 tgtattcaaa aagaagaacg aaacgctgaa ggatactatc cagacgatat tgttggaaag
     4561 atcttaggta gtgatgagct gggaatctac gttggcaaag acaaaattca ctacgacgaa
     4621 atacgtcata tcgaatttta ccaggataat aaatggagtc gattagaatg aacattatcc
     4681 agcaatatga gctaaagtat ataacctttg atcagctatc agaagagatt tgggggtatg
     4741 gccaacgttt gataaatgag gttggtgttg agcgtttctc tttctatgta gaagctgcag
     4801 caggttatca taattttagg ttttatattt tcccgttatt tatataaggt attttacgga
     4861 ttctatagag ttatctctat gaatcctttt ttgtttttac aaataggagt agata
//
LOCUS       DAIGSZ010000121         4741 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.125, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000121 DAIGSZ010000000
VERSION     DAIGSZ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.125"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(25..1023)
                     /locus_tag="NOB31_002769"
     CDS             complement(25..1023)
                     /locus_tag="NOB31_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HCI0974931.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1098..1394)
                     /locus_tag="NOB31_002770"
     CDS             complement(1098..1394)
                     /locus_tag="NOB31_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974932.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1387..1680)
                     /locus_tag="NOB31_002771"
     CDS             complement(1387..1680)
                     /locus_tag="NOB31_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974933.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1826..2377)
                     /locus_tag="NOB31_002772"
     CDS             complement(1826..2377)
                     /locus_tag="NOB31_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HCI0974934.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2551..2850)
                     /locus_tag="NOB31_002773"
     CDS             complement(2551..2850)
                     /locus_tag="NOB31_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HCI0974935.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2877..3143)
                     /locus_tag="NOB31_002774"
     CDS             complement(2877..3143)
                     /locus_tag="NOB31_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HCI0974936.1"
                     /translation="MDSLPVELQALCWNLIDQNVQKQFPLDYLQIFEFSTEKGNQKLV
                     HRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY"
     gene            3490..4173
                     /locus_tag="NOB31_002775"
     CDS             3490..4173
                     /locus_tag="NOB31_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974937.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIK
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
     gene            complement(4210..4707)
                     /locus_tag="NOB31_002776"
     CDS             complement(4210..4707)
                     /locus_tag="NOB31_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCI0974938.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1404 a          907 c          694 g         1736 t
ORIGIN      
        1 ttctttgata aataatattt tcaattattt aatcatttga aaattgttag tcattccaat
       61 acgttgagaa attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt
      121 gtttccatca tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat
      181 tagatctttc atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg
      241 agaatcatac aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact
      301 tgaaattcct gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc
      361 ttctactact ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa
      421 ctgttgattt tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg
      481 cgttaaataa actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa
      541 atattctcca gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt
      601 tccatcttct gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc
      661 attaatcacg gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta
      721 gcttttatat tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga
      781 agctttattc gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga
      841 acttgcactt gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt
      901 tttacttttt ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt
      961 ctcagatgta caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt
     1021 cattatattt ccccctttca atttctccct cacgtactta ttctatcaga caattaattg
     1081 atctaaatgg taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag
     1141 cggtctcttc cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat
     1201 cctctacagc gataagttct cattattttt gggctattag tattattttt cttagttaga
     1261 gctatgagtc caactatgat taccccaact gtcttaatta cttttccttt atctatattc
     1321 ggatgcgcaa gcatatattg atataaccaa tatccaccgt aaattaaacc acctaataca
     1381 atcagcttag ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct
     1441 tgcagagaaa ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat
     1501 catgttttcg attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat
     1561 ctgttgccct cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc
     1621 ctcaaaaaag tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat
     1681 ctacacaccc cctgttattt tttacataat gaaaatagca tattactggg tacattgata
     1741 attcatataa catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt
     1801 ataagtaaca tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca
     1861 attgccattc attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta
     1921 tcaatacttt ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt
     1981 gttcataagc cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga
     2041 ttttcttttc tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa
     2101 gaaatacccg aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag
     2161 taaatcctaa ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg
     2221 gttctgtatc tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc
     2281 ctttgatcgc ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa
     2341 cttctgtttg tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt
     2401 ttgttcaagc acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt
     2461 catattcttt ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa
     2521 catttcgcaa tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca
     2581 aaccaatcgt ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt
     2641 aatgaaataa actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt
     2701 catcactaaa cgtggtagat gaacatcttc aggaagcata cccatttcaa tttcctcttt
     2761 ttccatcgta acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt
     2821 ttccagtact tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag
     2881 tattcttctg gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga
     2941 gacactgatt tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct
     3001 tcttgacgat gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga
     3061 tagtctaaag gaaattgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt
     3121 aattccaccg gcaaactgtc cattactccc tttgtgacat aacgttatcc tttattttga
     3181 aacatttctt ttccctcctt tgccataaaa atagcccaat cttctattaa agaagattgg
     3241 gcttcatgga tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact
     3301 acacaattat taaagttttt catatctctt tgtttagtaa gtttttctaa atcttaaccc
     3361 gtggtgctag ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa
     3421 aaaacgcata tagtagtctc aaaactccca agaaatgagg actatttaac aaactacgat
     3481 ggttacgtcg tgacaactga acattttgac ttagccaatc ctgttactaa agtcgatgat
     3541 atccccgatt atgaaatgta cagtcaaaca atcgatagct taaataagcg ttttggcaat
     3601 cgtgttttaa aaggcatcaa aatcggttac atcgcttctg aaaaggatcg gatcatcgac
     3661 tatttagccg ataaagatta cgatttaaaa ttactcagtg tgcatcataa tgggcaattt
     3721 gattatttag atgacgaagt caaagatatg gatcctgcta ttgtgattcc tcagtatttt
     3781 gcacaacttt cagaagcact agttgttata gaagcagatg tctttgctca ttttgactat
     3841 ggttttcggg tatttggtct atccgttgct gaatttaaac aatatgaagc gcagttttta
     3901 ccgattctag atcaagtaat caaaaataaa ttggcattcg aattaaatgc taagagcgct
     3961 tacttgtatg acaatttagc gttatatgaa tatgtcatcg atttatatct ttcacgtggt
     4021 ggtaccttgt ttagtgttgg atcagatggg cattaccttg aacatttccg tttccatttc
     4081 gatgatcttt ttgctctgtt aaaagcaaat ggtgtgacgg aattagcgat ttatcaaaaa
     4141 ggaaagcgaa ttatggttcc attaccagtc taaaaaaacg tcctcagcat caaaagtgag
     4201 gacgtttttt tagatttctt tttctaaaat cggacaaata cgatcttgtt ttcctaaagg
     4261 aaaatgtttg atcccgattt ttttaaatcc atgacgttca taaaaacgaa tacctgcatg
     4321 atttttttca taaacagtca aacgtaaata acgtttttgt ttcgttttag cataacgatt
     4381 cgcttcatcg agtaaccgtt gccctaaccc tttgttttga taatctttga gcagatagag
     4441 ccgttgaatc tctatagcat ctttttcatc attgactttc atataaccaa tgagtatttg
     4501 atgatcctta ataccaataa atttactggt tgactgtgcc aattctactg ccaatatttc
     4561 agttgtcaat tgtgtctgta aatatccttg catatcaagt ggatctgcgc catcgataaa
     4621 cgattcataa aaactgacaa cacttacaac ttgtaaagca tctagatcat cataatctaa
     4681 atacgctagt gtgatttgat tgttcatcta actcctcctt ttgacatagt atactataaa
     4741 t
//
LOCUS       DAIGSZ010000122         4735 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.126, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000122 DAIGSZ010000000
VERSION     DAIGSZ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.126"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            62..1150
                     /locus_tag="NOB31_002777"
     CDS             62..1150
                     /locus_tag="NOB31_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974939.1"
                     /translation="MYSKNWKKKLVMGVMVGSIFVFAGCSASTDKSKTATSETKTAEV
                     VKSKMKQIEKNVEKILAEKDKDTKLSEYKKFVTESSAYSKSDKTEKKITNTYTESIKK
                     IKTNFKEQDDKDLKENTLDNLEEATENDLSQKVNTLDELKKWVQKESTDVYSQAEVDS
                     LIKKIDDTITTYKNQLEKIKIDNQEATSTETTTESSEVATLQENVSEEPQVVHTNLLN
                     SIEEAAQYLGQKLPQSGGSDAFENGQQNSDGSFTFHYQLHGGPEGITWNIITVNNNGE
                     IIQDDYFKTVPNEATNNNVSTLSQAAISELEAAQLAIAKHNELGRPNATDAGSETTAD
                     GYYFYYMADGTDQMYKYFVSNSGQVQAE"
     gene            complement(1607..1774)
                     /locus_tag="NOB31_002778"
     CDS             complement(1607..1774)
                     /locus_tag="NOB31_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017368673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HCI0974940.1"
                     /translation="MSIREIVRIQSFPDSYIFVGSSLSAKYKVIGNAVLPKLAKVIGD
                     SIVKQLSESNF"
     gene            1819..2241
                     /locus_tag="NOB31_002779"
                     /pseudo
     CDS             1819..2241
                     /locus_tag="NOB31_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752995.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3562..4647
                     /gene="xerS"
                     /locus_tag="NOB31_002780"
     CDS             3562..4647
                     /gene="xerS"
                     /locus_tag="NOB31_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HCI0974941.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT         1804 a          724 c          728 g         1479 t
ORIGIN      
        1 aatataacca cttttatgaa aagatgttat aattaactaa aaaataatag ggagaaaaca
       61 catgtactca aagaattgga aaaaaaagtt agtgatgggt gttatggtag ggtctatttt
      121 tgtttttgca ggttgttcag cttcgacaga caaaagtaaa acggctactt cagaaacaaa
      181 aactgctgaa gtagtaaaaa gtaaaatgaa acaaatagaa aaaaatgtag agaaaatttt
      241 agccgaaaaa gataaagata caaaactgtc ggagtacaaa aaatttgtta ctgaatccag
      301 tgcttactct aagtcagata aaacggagaa aaaaattact aatacctata cagaatctat
      361 taagaagatc aaaacaaatt ttaaagaaca agacgataaa gacttaaaag agaatacact
      421 agataatctt gaagaagcaa ctgaaaatga tctttctcaa aaagtaaata cattagatga
      481 actcaaaaaa tgggtacaaa aagagagtac tgatgtatat agccaagcgg aagtagattc
      541 attaatcaaa aaaattgacg atacaattac cacatataaa aaccaactag agaaaataaa
      601 aattgataat caggaggcta catcaacaga gactacaaca gaaagtagtg aggtagctac
      661 tttacaagaa aatgtttccg aagaaccaca agtggtccac acgaatttat taaattctat
      721 tgaagaagca gctcaatatc tgggacaaaa acttccacaa tcgggcggtt cagatgcatt
      781 tgaaaatggg caacaaaatt ctgatggctc gtttactttt cattatcaac tacatggagg
      841 tccagaaggt atcacttgga atatcattac agtgaataat aatggtgaga ttatccaaga
      901 tgattatttc aaaactgtac ccaatgaagc aacaaacaat aatgtctcta cacttagtca
      961 agcagctatt tcagagttag aagctgctca acttgcaata gctaaacaca atgagttagg
     1021 tagacctaat gcaactgatg ccggaagcga aactacagca gacggatatt atttttatta
     1081 tatggccgat ggaactgatc agatgtataa atattttgta agtaattctg gtcaagttca
     1141 agcagaataa cattgagtta taatgatatt atcagatgaa ctgtatcata aatttttaac
     1201 gtgaaatgtt tgtaatatca attggagaat ggtatatgga tttactaaaa gataataact
     1261 gttatttttt agtaaattca tactatttag aaaagaataa tttgctgaat acttgtaaac
     1321 tatgtgtgat acttatctta tatggatata gactcgtggt gctagttaat ttcagcttat
     1381 tataaaccaa cattttcatt ttataaaaac gactaaaaac agaatttctg agtaaaattt
     1441 caaaagtaaa aatagtgata ttatgctctt gttcctagat tcaataatta actagcacca
     1501 cgagtttata aaattggcaa taaaatttta atcattatta acataacctg gatctgtaaa
     1561 gcaatttaac tcttaataaa aaagcatcta aaaaaagcgt gttcagctaa aagtttgatt
     1621 cagaaagttg tttaactata gaatcaccaa ttacttttgc aagttttggt agaacagcat
     1681 taccaattac tttatatttt gctgaaagag agctaccgac aaaaatataa ctatctggaa
     1741 atgactgaat tctcactatc tctcttatcg acactcttag atgaactcaa aaaaatgggt
     1801 acaaaaagag aatactgatg tatatagtca actagaaata tcgctcatag agtgcgtgtt
     1861 cgaggtcgaa aagaaatctg tgaggagttc aaattgattt accatgcgaa ttcaaaagaa
     1921 gaggcattga attacatcga ttttatgatt aggaaatgga aaaagcagga tcgaagagtc
     1981 gtgaacctac tcttgaatcc tgccctatta accttttata atttccctta cgctatcaga
     2041 cgaacaattt attcaacgaa cctgattgaa ggctttaata agcagctaaa acgatatact
     2101 cgaagaaaag aacaattccc taatgaagaa tctctctaga gattcttagc ttcgcaattc
     2161 aactaatata accagaaatt tttaagtaga gttcacaaaa gatttaaaga aattcaagat
     2221 acattagagt cgatgattta actgtaatta acagaatgga ttttccattt acacataatt
     2281 cttgacgcta cctcataata attaagagct ttaaaattag tatttattag atacttaaaa
     2341 gctattttag tattgataaa ttgttaccag caacaaaaaa gaagttactt agtgctaact
     2401 tttgagcaac tgctagagga ggtaggatat ggctaattat cctgtaattt ttattgtatt
     2461 ttctagaaat gtaattattc tcttaaacat tccagcatat ccaagtatat agaaaattta
     2521 cgttttctat atagttggat gtttacaagt tatatctggt ttaataagtt tttttctgtt
     2581 agtcatggca tgttttattg tgctggttca tcaatatatt gaaatgtact aaaatgaaat
     2641 tttcagttat ggtataatat ttatgctgtc tgctaccccg gcctattatg gcaaggggag
     2701 gaggttgtat tatgaattac cttttcgata tgttttttgc aatcttagca gaagtatccg
     2761 cgcattacat ctgtaaatgg cttgattgca aaattattgc caaaaaagac agtaagccta
     2821 cccgttaatc tgaatagaac gtaaaagaaa accactagcc cgccagctag tggtttttgg
     2881 tgtatcatga attacctttt cgttaaaaca attataccat atttcctaaa aaatacaatt
     2941 aatagacgaa ttatcattac cactttgatg aaaaaagctg acataaattt ttcttttatt
     3001 tttataatga ataaacattt atcaataagc ttttgaaagg caggatcgta ctttgttgat
     3061 gattgagata ttgctacatc aatctcagca gttaagattt ttttgaattg ttgcttgaat
     3121 tttttcttta tctaaaaaaa ttgtatctcc aggatgcaac ccattttctt taagaaattc
     3181 cttttaaatt gttaatacta ctgagtgccc cacttctctg aattttcttt aacttctccc
     3241 tccccttttt tatttgtata tacattcata tacgcttgtt aatatcaaat caaccgtagt
     3301 ctctcttatg tctaattata tagaaagatt gttctttcta tataatttag acaatttaaa
     3361 aaattaagat tgcctccttc tgtttccttt cctattcatg tataccattt attttaaatt
     3421 attaaatcta tacctattta tctgcttttt tgaaataaat taataaattt cagagtatac
     3481 caattgacaa aacactctat aattggtata gtccaattat agagatactc ctctccccta
     3541 cttatcgaaa ggatgaataa catgaaaaat acagaaatat atcaaaaaat agatacaatc
     3601 atacttcata tgcccgatta tataaaagat tttgttcaag atcgtgagga taaagatcaa
     3661 tcacctcgaa ctactttaga atatctaaaa aattataagc tcttttatga atggcttctg
     3721 agtgagtcta tcgttcccga tacttcaatc acctcgataa gacagttaac tgcctatgat
     3781 ctaaacttgt acaaatctca tttgaaacgt cgcacaaagg aaaatgtaaa aaaagagaca
     3841 acaaaaacta agctcaaaga taataataac ttaggtctat ctacttctac tatcaataga
     3901 aatatcacag cattaaaggt tctatttaaa tatctttcga aaagttccaa taatccttta
     3961 ggaaaaccat acttagaaaa taatcctatg gatcaagtag caactatcac agataaaact
     4021 acgttagctg cccgtgcaaa cgcaatcgag aaaaaattat ttctagacga agatacacaa
     4081 aattatctag attatattgc caatgaatat aaaaaaactt tgagcaaacg agctttgatc
     4141 tattatcaac gagatgtaga aagagacctg gcgatcaatg cattgatttt aggatctgga
     4201 ttaagactct ccgaggttgt aaatattaat ttagaggacc tatctttaga aaagaataat
     4261 gtggtagtaa ctagaaaagg aaataagaga gacgcagtaa atatagcagc atttgcaatg
     4321 gaatatttag ctaattatct agctattcgg aaagaacgat acaaagtaac agaaaacgaa
     4381 aaagctttat ttctagcaat ttatcaagga gaagccaagc gtatatccgg tattgcaatc
     4441 gaacggatgg tagcaaaata ttcaaaagga ttcagagtcc aagtcagtcc acataaatta
     4501 cgtcatactt tggctactag actctatcaa cagacaaatt cattggtatt aactgcccaa
     4561 caattgggac atacaagtac aaatacaaca actttatata ctcatataga caatgcagct
     4621 acaattgatg ctttgaacgc tttgtaaatg tagtaaaaaa tagtataata atgaagcctg
     4681 tctctaaaat tagataaaag cccaacttta aaggcaagct tcattatcat tttta
//
LOCUS       DAIGSZ010000123         4650 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.127, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000123 DAIGSZ010000000
VERSION     DAIGSZ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.127"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            126..326
                     /locus_tag="NOB31_002781"
     CDS             126..326
                     /locus_tag="NOB31_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0974942.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            338..664
                     /locus_tag="NOB31_002782"
     CDS             338..664
                     /locus_tag="NOB31_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974943.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            817..1869
                     /locus_tag="NOB31_002783"
     CDS             817..1869
                     /locus_tag="NOB31_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI0974944.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            1945..2163
                     /locus_tag="NOB31_002784"
     CDS             1945..2163
                     /locus_tag="NOB31_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974945.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            2150..>4650
                     /locus_tag="NOB31_002785"
     CDS             2150..>4650
                     /locus_tag="NOB31_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974946.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKF"
BASE COUNT         1830 a          601 c          884 g         1335 t
ORIGIN      
        1 caaactatta tagcatgaaa accacaaatt gagtaatatt ttaattgata ttactcgttt
       61 tgtggtttaa aatgtgctta ttaagataaa aaccacaaag tgaataattt gaaaggaggc
      121 gctgaatgat aactcttaat gatcaattca ttagaagctt aagaagacat agagccgatc
      181 ttatacttac taaaaacgat gcagcaaaat tgataggtat aaatcggaaa acatatgtca
      241 aaatcgaaaa tgggagcaaa gaaagtatta gagcatctac ttatcaaaag ttggtaaatt
      301 ggttacttaa tgatttgaaa atctaaataa atacaacttg gcgagttggc tgattgaaga
      361 aatagaaaat gagaggagaa aaataatgga tgcaggaatt acagtaatgt tagataaaca
      421 acaaacgaat caattgaaaa attatgtttt tgaaatgaca aaagaggcta ttgatcaagc
      481 aagaattgat accggattag aaagaccatt tctaaaagga aaagagatgg ctaaatattt
      541 gaatgtatca tatacaactt ttttgaaatt taaaagaatg ggattgccag ttattttatt
      601 agaaaaaatg gagttgtttt caaaagaaga atgcaaaaaa tggatattga gtcatcaaat
      661 ttaaaaaaca cctcgttttt taaatttgat gaagtagaaa aaattaaaaa gagtgttccc
      721 gtcagtttgc agatcggggg aacactcaat aataaagttc tgagaaaact ttatttgaat
      781 ctattatagc aaataaaatc agaagcaggt gtgacaatga atgaaaaaga agttgaaagc
      841 ttagttgaaa agcaaggcta ttctaattct gatatatatg cagaattata ctatcaatat
      901 cctatttttt taaacgtaaa tgaaaaatat aagaaaatga aactaagttc taagttagtt
      961 tatatgttac taaaagatag aaatagactt tcattgaaaa ataacttgta tgatgagaat
     1021 caaaaaattt ttttgatatt tgaaatcaaa aatctcgtag aaatttcggg aatgtcaaaa
     1081 aatacaatct tatcagcact agatgaactt caaaaagtta aacttcttgt gaaaagaaaa
     1141 aatggcttca ataaaagtaa aatgcaaatg ttcccaaatt tttattattt gttaaagcct
     1201 gttctgtgca aagatgatgt ttataaaatt aataagataa cccatcaaga aaatagacaa
     1261 aaaaacttga tagttcaaaa tttgaactat ggaacaaatc aatattctgt tgatagttca
     1321 aaatttgaac tatgcgacac atcaatgaaa acaagagaca aaaacaattt tgctgatagt
     1381 tcaaaaaatg aactagaatt atataagtct tataaagata gtaaagatat taaagaatca
     1441 cataatgatg atcttcttga atcactttca actaaaaata ataaattaga tgaagaattg
     1501 atcgaaacat ttattgaaga aaatcttctt aaacaaatat ggggagaaag tattgtgaat
     1561 tgcttaaaac tggctagcaa tagtgattat cgtcaattcg acaactggta caaaaaattc
     1621 aaatatgcga ttagatctgc tgaaaaagaa caaaaaattc aactgaaaat tatctatgaa
     1681 atttgtaata acaagtattt tgtagatcat gttagagaac agctatcaat gactttacgt
     1741 gacttgatac gaagagcaaa aacagatcat cgtatcaaac aaaaagacga ttatatcttt
     1801 gcttctctaa aaaataaagc gttagaacta attgaattgc aaatcagcga aggaatagat
     1861 aagcaataag aatagaattg agtcaaatga aatggagggg tatctccact tcatttgaga
     1921 actttgaata taggaggggt tattttgatt aaaaatcgtt taatagatca agtttggtgt
     1981 ctagatcaaa atacagatag tctcgaatta atcgagacta tttgcttcaa cactatagtt
     2041 ctcgatttaa gagctgaaaa tgataattgt gtaactcatg tcataattaa tcaaaaaatg
     2101 gctcagaagc tctctgagag cctcagaaaa tgggctaagg gaggtaacga tgaaaataat
     2161 tgaaaaaaag attgccaata aaaaaataaa ttggttggtt gttaattttc ttgttctgat
     2221 agctatgatt atttttacaa gtaatattgc tcatgcgagt attttcaatt ggtttgatga
     2281 cacaaaaagt caaacagagt ttttgaataa ttctctttat agaccttacc taaaaaagta
     2341 caatggagat ttccttagtc agttcgggat ttggctcgga tgggctgtgg taaaaggcat
     2401 gtttactgtg acagattcga ttcaaaatat gattccagat gtgctggatt tgttcaattt
     2461 cattgaaagt acagggctaa ataatgttta tcaatcagcc gtaaatacaa ttgtcattgg
     2521 attaatgatc ctttcattga tgtttgttgg ttacaaaatg attactggaa aaggaacagt
     2581 ggatttaaaa tcggttggaa tgaacgtagt gatgtctata gcattaatac ttttaatgcc
     2641 aaccatgatt tctagtggta ttcaatttgc taaaacattt tataaggact ctactacgat
     2701 tacaaattca gatgacggag tcgcttggtc attgataaaa caaggagtaa cagatttagc
     2761 atatattaat aaaacagatc agtactcaag cattgataaa acggaggatc gaaataattt
     2821 aacacgaaaa aattttcaac agacggatct cacacaagtg ttaacggata aagtgattga
     2881 taaattggaa aaagaaaatc caattgcgga caatcttcgt tatgaattag ttgaaaattc
     2941 taataatgaa tttgttgcta caaagttttc tgacaacttc ttatcaacat tttctgatag
     3001 cttgaaatca ggctattacc gataccaagc aaatctatgg gggatttcaa ttgggttgac
     3061 agcgttagca atcgcctatg tgttcagcgc gtttgtgatc attacagcaa tactagaact
     3121 tgcatttaaa cgtgtgttag gtgttcttgt ttttgcaaca gatattgaga caggacagcg
     3181 ttcaaaagtt gttctatcag atattctaca atgttactta actgttgggt ttcaaggatt
     3241 tgggttatca atgtttgcta tgtttatcaa ttttctgaac tcaggacaag gtatctcaac
     3301 aaatattttt ataaaaacaa ttgcttatat ctgtgccgtt tttgttttaa tcaaaggcag
     3361 tggaacagtc atgagatact ttggtgttga tattggactc aaagaaggct atgggcaact
     3421 tgcttctgct tttggaatgg gcgcaatgct gtttagaaaa ggatcaaatg gatttaatcg
     3481 tgctaaagga agcggagaag gagaagatcg aaaaccagaa aagaatttcg gcgaaactct
     3541 atcaaaaaaa gctggcaaaa ctggaagagc tttgggatat gcccatgaac gtggattatc
     3601 cggtttagct tcagatggag ctacaatggc tagtgaaaga gcaacaaaac catttaagag
     3661 tatgcgtgat atagctaatg ataccaagaa taagtttaaa gaaggtttag atgatggtac
     3721 agtgtccgct attaataaaa atagcaaacc tatgttagct aaaaataaag aagatgaaac
     3781 tggaaaatat gctgattccg tgccaacacg tctttcagat agaaaagatg gtgctaaagt
     3841 tgaaaatgcc gatagaatta tgtctagttc tgaacgtatg cgtgaagcaa tgaaaaataa
     3901 tgctgaatcg aataataatc ctgcaagcgc aattcagcaa aaagtccaac aagatattga
     3961 agaacgtaaa aatgctatgc acggtcaagc taagtctgct gaagaattaa ttaatcagaa
     4021 gcgtcatgaa gcgaaataca cgcctgaagc aatgaatcgc gaggaaataa tgttaaggaa
     4081 acgtgtagaa gggcggacag gcgctaatat tgacggaaaa gaagcgttga ccaaagaaag
     4141 aattcaagaa gctaaaaatt caaatacagg attagaaaaa ttagtcaaag aaaatccaca
     4201 aaattctaca agtagtcatg gtggccgatc agtagatgtc cgagaaaata ttcaaggttc
     4261 actgaatggt catgttggac ggaatgttga tgtaagagag aatttacaaa gttcttcaaa
     4321 tgctcaaggt actaagacaa ttgatgttcg agaaaatctg caaagtagca gtacaagtca
     4381 accaaaaaca gtagatgttc gagaaaatgt acaaaattct acaagtagtc aagggtttaa
     4441 atcagtggat gtccgagaga atgtgcaagg tagcagtgca agtcaaccaa aaacagtaga
     4501 tgtccgagaa aatgtacaaa gttctacaag tagtcaagga ttcaaaacag tagatgttcg
     4561 ggagaacatt caaaaagata gtggagaaat gaaagaaaaa acacaaaaaa tcaatatcgt
     4621 tgaagacaga aagtcagcga aaaaatttga
//
LOCUS       DAIGSZ010000124         4642 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.128, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000124 DAIGSZ010000000
VERSION     DAIGSZ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.128"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..833)
                     /locus_tag="NOB31_002786"
     CDS             complement(<1..833)
                     /locus_tag="NOB31_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HCI0974947.1"
                     /translation="MERNSENKMTGRNPKVFISYSWENKENKEWARELADKLLENGID
                     AYIDQYDLSLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAEL
                     LSGKNERKFIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKP
                     ALGDIPRHIKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRV
                     PSQLWKELFVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIE
                     K"
     gene            complement(1352..1765)
                     /locus_tag="NOB31_002787"
     CDS             complement(1352..1765)
                     /locus_tag="NOB31_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCI0974948.1"
                     /translation="MIYLSEKDIVKLNVIQIKKYSPRETIGVIDKNALSMAVNQPKQH
                     IFGKDLYPDKFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMKNQEVV
                     EFVVEIATYQGDFDDLKEATTDILKKNSTKTDSKK"
     gene            complement(1762..1998)
                     /locus_tag="NOB31_002788"
     CDS             complement(1762..1998)
                     /locus_tag="NOB31_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HCI0974949.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMME
                     AIVKEESKIDLEIDMYVNQALSEYDAAFKELVEK"
     gene            complement(2353..2955)
                     /locus_tag="NOB31_002789"
     CDS             complement(2353..2955)
                     /locus_tag="NOB31_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974950.1"
                     /translation="MEDIILRDRLTDPLKNSLANVIYDILREADKVYSNYNGKVSWVI
                     YSFLIKEFFKEQINNSYELGYHFTVYYEDIIKRLEDLEWYAYYDLLEVFASAKILDKK
                     KREEVNKILESENSGYRLSESNEFIPITDDISIKSINAVSESPFNYAKNHIHKSLTYI
                     SEKENQDYNTVVREAISAVESCLIEFSGLPANKKILWELL"
     gene            4027..4239
                     /locus_tag="NOB31_002790"
     CDS             4027..4239
                     /locus_tag="NOB31_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0974951.1"
                     /translation="MKNRLEELRKQRGIKQEDLASALEVSRQTIGSLENGRYNPSIIL
                     AFKIARYFQMSIEEIFIYEEESEDEK"
     gene            4229..4624
                     /locus_tag="NOB31_002791"
     CDS             4229..4624
                     /locus_tag="NOB31_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974952.1"
                     /translation="MKNKGQIWYIGYIVSLFLIVTILVTDFPKMVDIGLAILFSAVFG
                     VSHVQILHDKMIKNDADYKINVMDERNIIIKEKAGNITNMFNTILLGVATVIFICLDY
                     IIPAIIVGSIIAIQPIILIIISSVLEKKM"
BASE COUNT         1535 a          773 c          636 g         1698 t
ORIGIN      
        1 cttttttcaa tgcaaagttt taaagtttcc cgatgatatt cccggacttc ctcaatagtt
       61 gttccattaa gtaaaatttc atcgtctaca acagaagcaa ttcctggtct atgcattgtt
      121 gtatatcgtg gtggtgaatt ccaatttcta acaaacaact ctttccaaag ctgacttggt
      181 actctattta atctaaatgg aattttatat aatgcagaac cccttgagcc atccatttta
      241 ggtacagtta ctttatcagt gataattcct aagatttcaa tatctttatt ttcattatgt
      301 tctataggta gtaaaggact gcctttaata tgcctaggta tatcacctaa tgctggtttt
      361 ctcttaacac caaatatagt tgtaattaaa tcatctaagt tttcatcata atgctggcta
      421 tctgataaat caattccaag ctttccagca agaaaagtag gaagtacttc gcttgcacgt
      481 ccttctttaa ttattgggat aaatttacgt tcattttttc cagaaagcaa ttctgctgag
      541 ataatatgac cttcataccc aacaccactt gtacgattat ttgccttttt tttatactct
      601 ggtgtacata taattagaac ataatctgaa tcggatattt gctgctccat aaactgaggt
      661 aatctatcac ctaaacttaa atcatactga tctatatatg catcaatacc gttttcaagt
      721 aatttgtctg ctagttctct agcccattct ttattttcct tattctccca tgaatatgat
      781 ataaatactt tgggatttct accagtcatc ttgttctcac tattcctttc catcactaat
      841 ctaagtgcta actatttggt aatacattac aattatatca ctcaacaagt taataaattt
      901 taattcagga aaattcatca aaattatttt caagcgtatt ctcagctaaa atgaacttgg
      961 ataaactctt aatttagtga ttttcaccga attaaaaaaa tgaatccgaa gttgaaaata
     1021 agtcttccta ctttatcgtg tacagtacgt tagacattaa ttgattaaaa gaagagcagt
     1081 agaccaggaa ttaaatataa attatcattt gatcagataa tcattctagc ttctttgaaa
     1141 atagatagtc attagttttg gagagagtag agtattacat aacatgcttg cttaagcgat
     1201 taaggtcatt ggtttacata aataaattgg tattataaaa aagtttatta tttaagcttt
     1261 taaaataatg aacttcgcat aatgtatctt atgtaaacta aaataaagaa caaactaaat
     1321 cttcagattt aactgaatcc ctagtttgct tctacttttt tgaatcggtc tttgttgaat
     1381 tcttttttag tatatctgtt gttgcctctt ttaagtcatc aaaatcaccc tgatacgtag
     1441 caatttcaac tacaaattct actacttcct gatttttcat ttttagtgaa tagccattta
     1501 gcttgagaaa aacatacgcg gctaaaaatg ctgtacgttt gttagcatta tgaaatggat
     1561 gctttttgat cagatttatt agcagaacag ctgctttgct aaatttatca ggatacagat
     1621 cttttccaaa aatatgctgt ttaggttgat ttacagccat actcagcgca tttttgtcaa
     1681 tgactccgat tgtttctcgc ggtgaatatt tctttatttg aataacattc aattttacaa
     1741 tatctttttc acttagatag atcatttttc aactaattcc ttgaaagctg catcatactc
     1801 agataaagct tggttaacat acatatcaat ttcaagatct atcttgcttt cctcttttac
     1861 aatagcttcc atcattttat cttcatcaat aaaaatagta tctccaggtt tcaaaccttt
     1921 ttgcaataaa ctctcttttg acaaagttac aactattgaa ttacctactt ctctgatttt
     1981 gcgtttttta atattcatat catcaactcc tacgataagt atacaccgta tatccgtatt
     2041 gttcaatcac ccttattact tccttcaatt actaaacttt taaagagttg gaaattaata
     2101 gttataatgt agctcttgga tgaattttaa cttttcatga tttattggag tcatatgcta
     2161 tttttactcc caaataatta attacggctg aacatgttgt taacaccaaa actgcatcag
     2221 gtaaatctga gacaattgtt ttttcatttt ctgcatgtcg tattccatta ttactcgcca
     2281 aaccatacat tgtctcaaat ggttttaaaa atgtaagatc gacattgtta ttcgatttgt
     2341 ctttaattgc ttttatagca gttcccaaag tattttttta ttagctggta atcctgaaaa
     2401 ttcgataaga caactttcga cagcactaat tgcttctctc actacagtat tataatcttg
     2461 attttccttc tcgcttatat atgtaagaga tttatggata tgattttttg cgtaattaaa
     2521 tggtgattca gatacagcat ttatagactt aatagaaata tcatctgtga ttggaataaa
     2581 ttcattgctt tcgcttaatc tgtaaccaga attttccgac tccagaattt tatttacttc
     2641 ctctcttttc tttttatcca agattttagc acttgcaaaa acctctaata aatcataata
     2701 agcataccac tccaagtctt ctaacctctt gataatatct tcataataaa cagtaaaatg
     2761 ataacccaac tcatagctat tatttatctg ttctttaaaa aactctttaa ttaaaaaaga
     2821 atatattacc catgagactt ttccattata attactataa actttatcag cctctcgtaa
     2881 tatatcataa atcacatttg ctaaactatt tttaagaggg tctgtcaatc tatctctcag
     2941 tatgatatcc tccatttttt aaaaccaaat ctttcagaaa aaagcattgc actacctcca
     3001 gtaaattaac ttatactcat ataactttac gaagcaataa ttattcgtgt tgttttacat
     3061 aaataaaatg aaatatctgt taagattgtt taatggcaca aacataaatt attatataat
     3121 tacgtattaa tttatctaga tctattaata atactgatcc ctaataggtg taaaacagtt
     3181 ataagaaatg agtactctag tatttgtgtt acccgaataa ttacttgatt atattggttt
     3241 cccatataat tgaaggctgt cctaattttt acctactata tgatcataat tgattaactc
     3301 ttatatattt ccgaaaatta tcttgaagat ttctattggt atggagaata tccatttcat
     3361 tgccaataag gatataaatt ctcaaaataa caatcgatgt ctgtattaaa caagcctaga
     3421 atggtaaatc tgattcgcca aaaccattgg attgtatcga tttgctttac gcgaacgcca
     3481 cctacccatt ttataaaaat aaaatgggca aaagatcttt ctttttgtca tacaaaaaga
     3541 agaaaaaaaa gagacgattt tcttcttcca aaatcgtccc tcttttttct aaaaccatgg
     3601 atgaacgaac aaaaaatctc tcgtattttg tttgttcatc cactaaaaat atgcgaacag
     3661 tatggtttca ttcaatcctg ttcttacaag tcaaaagcat cgaatcgtcc ttggacgatt
     3721 caacaaaaaa agtagtcgtt tttggatgac tactaagttc taaacattca ttacccaaaa
     3781 tcaatttggt ctaacatcgt ttctcgactg gcttgatcta atcggctctt gacagggctt
     3841 tttcttttct gttgatagca gataagagga aataagaata agtgtgttca tgtgtcataa
     3901 aaacagtaac taaaacatta aaatcaaaat ttatatggaa agcttccttg acattttgtg
     3961 ctcgcaggag tattataaaa gcacgaaagg aaagtaaact ttccattttt tagaaaggag
     4021 catgttgtga aaaatcgttt ggaagaatta cgaaaacaaa gaggaattaa acaagaagat
     4081 ttagcttctg ctcttgaagt atctcgtcaa acaataggtt ctttagaaaa tggacgttat
     4141 aatccctcta ttatattggc atttaaaatt gcaaggtact ttcaaatgag cattgaagaa
     4201 atttttatct atgaggagga aagtgaagat gaaaaataag ggtcagattt ggtatatcgg
     4261 ttatattgtt tcgttgtttt tgattgtgac aattttggtt acagattttc ctaaaatggt
     4321 agatattgga cttgctattt tattcagtgc cgtttttggc gtttctcatg ttcaaatttt
     4381 gcatgataaa atgattaaaa atgatgcaga ctacaaaatc aatgttatgg acgaacggaa
     4441 tatcataatc aaagaaaaag cgggaaatat aacaaatatg tttaacacaa tactgttagg
     4501 ggtggcaaca gttatattta tttgtttaga ctacatcatt ccagctatta ttgtcggaag
     4561 tatcattgca atccagccga ttattttaat cattatcagt agtgtgcttg agaaaaaaat
     4621 gtagaaataa aggttcatac aa
//
LOCUS       DAIGSZ010000125         4620 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.129, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000125 DAIGSZ010000000
VERSION     DAIGSZ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4620
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.129"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(29..1261)
                     /locus_tag="NOB31_002792"
     CDS             complement(29..1261)
                     /locus_tag="NOB31_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HCI0974953.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1516..2085
                     /locus_tag="NOB31_002793"
     CDS             1516..2085
                     /locus_tag="NOB31_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0974954.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2263..2703)
                     /locus_tag="NOB31_002794"
     CDS             complement(2263..2703)
                     /locus_tag="NOB31_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HCI0974955.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2861..3625
                     /gene="map"
                     /locus_tag="NOB31_002795"
     CDS             2861..3625
                     /gene="map"
                     /locus_tag="NOB31_002795"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HCI0974956.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3657..4580
                     /locus_tag="NOB31_002796"
     CDS             3657..4580
                     /locus_tag="NOB31_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HCI0974957.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
BASE COUNT         1397 a          857 c          912 g         1454 t
ORIGIN      
        1 tattttttgc atgtgtgcga aagtatactc aagcccaatc gccatttcgg aaaatcggta
       61 ctgtagagcc atcttcacgg attccgtcga tatccatctt gtcagatcct accatgaaat
      121 ctacgtgggt ttgacttcta ttcaatccag cttctgctaa ttcttcatcg gacatttctg
      181 taccgccttt cacactgaag gcataagcag aacctagtgc taagtgattc gatgcgtttt
      241 catcaaataa tgtattgaaa aagatgatgc cagattgaga aataggtgaa gggtcaggta
      301 caagtgcgac ttctcctaaa cgacgcgcac cttcatctgt atcaagcagt tttgctaaga
      361 catcttctcc ttgttcggca gaaaaatcaa caacttttcc atctttaaaa gtaaatttca
      421 tacccgagat gatggtgcca gcataactca gtggctttgt acttgaaatg taaccatcta
      481 ctcgatgact gtcaggtgct gtgaacactt cttccgtcgg catatttgcc atgaattttt
      541 ctccacgagc attatagctt ccagcgcctt cccaaagatg gtttttaggc aatccgataa
      601 tgatatctgt accgggagca gtatagtgaa gggcagaaaa ttgttctcga ttcaattctt
      661 ctgctttttt tgctaatttt tcatcatgct tcttccatgc taagacaggg tcttcttcat
      721 agacacgagt cgttttgaaa atctgatccc ataatgcctc aacttgtttt tcttctggca
      781 gttctgggaa gacttttgct gcccattgtt taccagccgc agccacgaca gtccaactga
      841 ctttatttgc ttgagttgcc ttgcgtaaat tcattagtgc tttgccattc gctgattgat
      901 aagacgctac tcgatggcta tctacaccag caaatgcatc gggatcggca gaaacaacgc
      961 tgatcctgct tgctcctttt tcaagccatt catccgcttg atcgatttta gattgtggta
     1021 cattctcaat acgatccgtt gcagcatgta aaagaaattc tctttggatc tggtcgtcag
     1081 tccattgaac gataacctca gcggctccta gtttataagc ttcttgtgtg atcaatcgag
     1141 caaggggtgc ctgttccacg ctgatctgta aaacaactgt gtgtcctttt tctgtggcta
     1201 cgccagtttc tgcaattaag cgtgcatatt tttttagaag ttcattaaaa tcagataaca
     1261 taataaaaat tcctcctcac cattttttct ggtaactatt agcatgatac catttaatta
     1321 tgattcaaac aatgaggctt taaataaaaa aaggaggtta tttttttaag gttaagtttc
     1381 atgatatatg ttactacttg ctatttcagc ttgtgaagaa aatcaaaaac taattttgca
     1441 tatcaaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta
     1501 aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct
     1561 gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac
     1621 aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga
     1681 caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat
     1741 acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag
     1801 aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc
     1861 tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa
     1921 gagcagatcg aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg
     1981 atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt
     2041 atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt
     2101 ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca
     2161 gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat
     2221 acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag
     2281 ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt
     2341 aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac
     2401 cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc
     2461 caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc
     2521 atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc
     2581 tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac
     2641 aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc
     2701 catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt
     2761 gaaaagaaaa taaaacctag agacacctgg ggaatgtcat ttggctaaat gtatgccgct
     2821 atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc
     2881 acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct
     2941 gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta
     3001 tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac
     3061 ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa
     3121 cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg
     3181 ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa
     3241 gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg
     3301 tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg
     3361 tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg
     3421 aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg
     3481 aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact
     3541 ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc
     3601 acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga
     3661 aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa
     3721 agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct
     3781 tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc
     3841 aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg
     3901 gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat
     3961 tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag
     4021 cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca
     4081 ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga
     4141 ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa
     4201 ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa
     4261 ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg
     4321 tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga
     4381 tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg
     4441 ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc
     4501 atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat
     4561 tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat
//
LOCUS       DAIGSZ010000126         4587 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.130, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000126 DAIGSZ010000000
VERSION     DAIGSZ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.130"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            186..2855
                     /locus_tag="NOB31_002797"
     CDS             186..2855
                     /locus_tag="NOB31_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HCI0974958.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="NOB31_002798"
     CDS             complement(2946..3566)
                     /locus_tag="NOB31_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCI0974959.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="NOB31_002799"
     CDS             3680..4219
                     /locus_tag="NOB31_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974960.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="NOB31_002800"
     CDS             4216..4554
                     /locus_tag="NOB31_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HCI0974961.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1419 a          790 c          860 g         1518 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgac
//
LOCUS       DAIGSZ010000127         4428 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.131, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000127 DAIGSZ010000000
VERSION     DAIGSZ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4428
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.131"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(543..2048)
                     /locus_tag="NOB31_002801"
     CDS             complement(543..2048)
                     /locus_tag="NOB31_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0974962.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="NOB31_002802"
     CDS             complement(2045..2731)
                     /locus_tag="NOB31_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0974963.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="NOB31_002803"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="NOB31_002803"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HCI0974964.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1237 a          919 c          729 g         1543 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaac
//
LOCUS       DAIGSZ010000128         4281 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.132, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000128 DAIGSZ010000000
VERSION     DAIGSZ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.132"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            75..503
                     /locus_tag="NOB31_002804"
     CDS             75..503
                     /locus_tag="NOB31_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCI0974965.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFLI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
     gene            490..732
                     /locus_tag="NOB31_002805"
     CDS             490..732
                     /locus_tag="NOB31_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0974966.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(1032..1247)
                     /locus_tag="NOB31_002806"
     CDS             complement(1032..1247)
                     /locus_tag="NOB31_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974967.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            1354..1668
                     /locus_tag="NOB31_002807"
     CDS             1354..1668
                     /locus_tag="NOB31_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0974968.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            1772..2950
                     /locus_tag="NOB31_002808"
     CDS             1772..2950
                     /locus_tag="NOB31_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0974969.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            3353..3646
                     /locus_tag="NOB31_002809"
     CDS             3353..3646
                     /locus_tag="NOB31_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HCI0974970.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         1465 a          647 c          822 g         1347 t
ORIGIN      
        1 tcctagattg tagtaataat ggaaagggat agaagtaaaa cgagttgaat gaattttttg
       61 agggggagaa tattatgggc gactcagagg aaacccacat tcaacatacg tttgacagtt
      121 tttgtaagaa agtagtctgc aatgaggcgt taaatattca aaagaagtac gctagatttc
      181 gccaacggca aatatcaatg gaaatattgg aacaaaaagg gttaggtaca gagttctatt
      241 atttggaacc aaatttgaat agtagtggta cttttattgt ccttggtatg aaaatcttta
      301 tttccaatga ggagttggca aatgcgattg cagcattacc tagtcaaaga caagaaatca
      361 tttttatgtc cttcctcatc ggtcttaatg atcgtgaaat tggcgatatt attgggaaaa
      421 gtctcggcag tgtttggtac caacgacaaa tggctttgga agagctagga aagtatttgg
      481 gtgtcaaata tgaagcaaaa taaacgatat ataccattca taccactaac gacaatcaaa
      541 gccgcagctt ctggtgattc aattgccatg tccatcgttc tgtcaaaata tcaaaattat
      601 atttcacggt tagccatgaa accagtttat gaagaagaaa aaggaatggt tatgtatgta
      661 gatgaatata tgcgtagaca actggaaaca aaattgattg agaagatact tgaatttgat
      721 acaactcgtt aaagtatttt ttccctttcc ttttcattct atggaagttt tttatcgggt
      781 caaaataaag gatttccata ggctgaaaat agcctagcgc tctttgacaa atgaatagca
      841 aatctatcag tacatgtaga ttttgattct ctagttacgc catgacaagg ttagctttta
      901 agcgacaaat tttaatatga gaatcgcgac tacgataatg atacttccgt aaccaaatcg
      961 gcccgccatt actgggggga ggtgagattc ctatgtgctt tggcaaaaca gctgatagat
     1021 cagaaaaact actatttcca tatttcgatt ttggttggca tatttttcat gccaaattct
     1081 gtgattttaa tagcatcggc aagatttaat ttttcttcag ctctctctcc acttttaagt
     1141 ttttttactg tactcaagtt gattcctgtt ccgaatgcta ttgcattagc cgtagatttt
     1201 tcaagaattt ctttaattat ttttatgtct gcaattcctt gtttcatatt aaaaattcct
     1261 cttttctagt ccgttttgat ggagtactgg agtgtttttt tacaatttta aggggtaccg
     1321 tggtggtcgt tttgattttg agagagaagg gtgatggagt tggaagttaa aacaaatgtt
     1381 aattctctgg aaatagagtt ctattcaatt ttacaaaaaa aactggaaga ttacacggaa
     1441 aaattgcttg cagtcagtca tttacctctg gtattaacaa atactgattt aaagcgacta
     1501 tttcagataa gtgatagtac actgaaccgt ttagtaaaac ttggtgagtt tcctccctgt
     1561 tggtacggga ttcgaggaca ctattttcgt gatgatgttt tagaatggat gagaaagagt
     1621 gattcgaatg actatcgaga aaaattgcga ctacttcgat ctttataagt tacattttct
     1681 ttctaagatg cggtacaatg atgacataga tagaaagatt tccaaagggt ttctgcttgt
     1741 tgggttcctt caaaatagga ggaatcaata aatggaaaaa acagatcgat tcaagaagca
     1801 aatcagttct actggtagga tcacatggta ctttcaagca tatcgaacaa caagacgtgg
     1861 ctttaattca aaacgtgagg cgcaactcgc ttatctggaa atggagaaac aacaaaggct
     1921 taagaaaaaa attgttgcaa gcaatgacaa gtttagtgtt gtaggtgagc aatggttcca
     1981 atattaccgt tcgttaaatg aacaaaagga aataacctat gataagcgag aggaacaatt
     2041 aaaaattatt gttcgatgga ttggtgataa aaagttgtct gatttgacac cagagtgcct
     2101 tcaagaattg ctttttacct taaaggaatg tggcgttaat ggaacaaatg ttggctatgc
     2161 caaaaatagt ttacaatcac ttattcaagt tctaaatatg atttttaaat attgtcaaag
     2221 aaagaatttg ataagtgaaa atccaatgaa gtctgtgaga atgccaaaat atcagttaac
     2281 ggtaactgat ttaaaagaag ccataaataa tattgaggac aagtttctta ctgtcgatga
     2341 attgagaact tttttgaatt atggcattgt tcatgaggaa ttaccgatgt ctgtactttt
     2401 ccatgttcta ttttacactg gctgccgagt cagcgaggcg cttgctctac agcctggaga
     2461 tatagatttc aaaagaaatg aaattctgtt ctataagcaa acggcagtta aaggtaagag
     2521 taaggatttt cgaattgaaa ctactaagac agttagttct gctagacgag ttctagtaac
     2581 tcctctagtt atggaaaagc tacaacagtt gattaaggct ttgggtgaga tgaggcaaca
     2641 ttacaggttt attatagaag aaacatattt gtttgtgtat cttgattcta gtaaacgtgg
     2701 tgttccttat cgtcgagagt atgtaaatga tcacgtcaaa cggtgcgtga atcgctcagg
     2761 aattaataag ccatttcata ctcatttagc tcgtcataca atggcaagct tagtagcgga
     2821 acactgtagc tgggaagtct tgaaagatcg cttaggccat actgaccaaa caacttcgaa
     2881 aatttatcgc cacttaacgt caaatgaaaa ggtaaaacct ctgattgctt ttagttcttt
     2941 agagagttaa aaaaacggtg aaagcactgg tattacagga ttcttgaaaa acgatttttt
     3001 aacaaattag tcaatatgta gtcagaggta ataaaaatcc ttttatatca atactttaac
     3061 gacttttcac aagtatcaaa gaaatccgtc gttaatcatt gttatcagac tgagaaagaa
     3121 cccttggtat tcaagggttc ttttttctta gcatgtaatt tgaacaccct gatccagttt
     3181 tttctttaat tattggtagg ggagaataat ggattagaat aaatctacct ataagtagta
     3241 gtaaaaaaaa gagcactatg ataatatctt tcttaagagt aaccgcttta ataaaaaatc
     3301 cagaatattc taacataaat ggagtattct tagaatcaaa aggagaaaga agatggttta
     3361 tacttatacg gagcaagaaa agatgaaagt tttagacaca ttcatgaatg atggaaaagt
     3421 aaaacaagta ccaagttcaa caaaaaagaa atacatccta ttgaaagaag tcttgaaacg
     3481 ctttgaccat ggagtgactt atacagaaac agaggttaat tcgatactgc tgaacgtatt
     3541 ttctagtggc gattatgtcg aacaaagacg ttatctaatc acatttggct ttttcaaaag
     3601 aagttcagac ggtcgggcat atcagatgat gggaattgaa aattagaagt tttaatttat
     3661 actcattgaa aaaagttcaa gtatgcgata ttggttctac accgcatact tgaacttttt
     3721 ttgtcatctg tatctataat acaaagccaa gaacgttatt caaaatatgg atagctatga
     3781 taaaagctaa tgagcgattc gcagttaaat aagcaatcgt cagtaaaatc gttccaggag
     3841 cgtacatgaa aaaatcaatt ggatgcgtta catgaataaa gataattctc ttttatttgt
     3901 acgaataaat accaaaacgt acctcctaaa attagatttt ggacagatgc cctttaaaaa
     3961 gataacaaga tttcgttctt gaaacaatat atatgctttt attccaatga ggttgtgaaa
     4021 acagtatttt gtcctgagcg ttagaaaatt gaaaatgggg aatagcaact cgtactttac
     4081 cattttttaa gtgaatacaa gatcagctaa ttgaacaccg tttattcgtg atgagggaca
     4141 caacactgca gtcgacacat ttctctttta tgttcaaaga taacaaatat ttaaaacaaa
     4201 gaaaaatagt agataatccc gtcctaactc ttttattctt ccctcatagc ttccaaattt
     4261 aagcaatact tcaattaatc a
//
LOCUS       DAIGSZ010000129         4233 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.133, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000129 DAIGSZ010000000
VERSION     DAIGSZ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.133"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="NOB31_002810"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="NOB31_002810"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HCI0974971.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="NOB31_002811"
     CDS             complement(1173..1868)
                     /locus_tag="NOB31_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HCI0974972.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="NOB31_002812"
     CDS             complement(1881..2597)
                     /locus_tag="NOB31_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HCI0974973.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="NOB31_002813"
     CDS             2927..3532
                     /locus_tag="NOB31_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HCI0974974.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="NOB31_002814"
     CDS             3857..4180
                     /locus_tag="NOB31_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HCI0974975.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
BASE COUNT         1222 a          842 c          767 g         1402 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttg
//
LOCUS       DAIGSZ010000130         4109 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.135, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000130 DAIGSZ010000000
VERSION     DAIGSZ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4109
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.135"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            148..309
                     /locus_tag="NOB31_002815"
     CDS             148..309
                     /locus_tag="NOB31_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCI0974976.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            328..1605
                     /locus_tag="NOB31_002816"
     CDS             328..1605
                     /locus_tag="NOB31_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0974977.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1615..2271
                     /locus_tag="NOB31_002817"
     CDS             1615..2271
                     /locus_tag="NOB31_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCI0974978.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2271..3647
                     /locus_tag="NOB31_002818"
     CDS             2271..3647
                     /locus_tag="NOB31_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCI0974979.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3777..>4109
                     /locus_tag="NOB31_002819"
     CDS             3777..>4109
                     /locus_tag="NOB31_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0974980.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1628 a          452 c          725 g         1304 t
ORIGIN      
        1 aggcttacca gcgagataga gatcgacgat ttgttgtttg aattcttttg aataggttct
       61 tcgttgacgt cttggcatga aaaatcctcc agtgtgtttt ttattattct acacacctta
      121 ttttttctgt ctagtctagt gtagccgatt caggataagg ataagtgtat taattgtgga
      181 aaatgtaaaa aagtttgcca aatgaataaa gattcagttg agaattgcaa tcatctggag
      241 tgtatcagat gtggacgatg taaaaatgct tgtccagtgg atgcaattag ttatggagta
      301 agaaaataga aaggagtagt taggaaagtg ataaaaaatg ctatagcata tattacaaga
      361 aagaaaaata gaactttaat aatttttatc atattaacta tagttctttc ttgcttgtat
      421 tcttgtttaa caataatgaa atcaagcaat gaaatagaaa aggctttata tgaaagttct
      481 aattcttcaa tatcaataac aaaaaaagat ggtaaatatt ttaatgttaa tcaatttaaa
      541 gatattgaaa aattaaaaga aattgaagaa aaaataattc aatatgatgg attagcaaaa
      601 ctaaaagatg ctaaagtagt tagcggagaa caaagaataa atagagaaga tttatctgac
      661 gaatttaaga atgttgtttc actcgaagct acaaataata ctaaaagaaa tattttattt
      721 agtagtggag tatttacaat taaagaaggt aaaaatatag aagaaaatga taagaattca
      781 attattgttc atgaagaatt tgctaaacaa aacaatctaa aattaggtga tgaagttgat
      841 cttgaattac tagatattga aaaaagtgga aaaataaaaa gtcataaatt taaaattata
      901 gggatctttt ctggtaaaaa acaggaaaca tatacaggat tatcttctga ttttagtgaa
      961 aatatggtgt ttgtagatta ttcaacaagc caagagatat taaacaattc agaaaataat
     1021 gaaattgcaa ataaaatttt aatgtattct ggtagtgcag aatctacaga cttagcctta
     1081 aacaaattga aagagcttaa aattgatgag tcaaagtatt ttgttgaaaa agattctaat
     1141 gcgtttgaag agtctttaga gtcagtgagt ggaataaaat atataataaa agtaatgact
     1201 tattctatta tgttgggtgg gatggttgtt ctttcattaa tcttgattct atggttaagg
     1261 gaaagaattt atgaaatagg tatattctta tctattggaa catctaagat acaaattata
     1321 atgcaattta tattcgagtt aatattcata tcgataccaa gtataatatc ttccttattt
     1381 ttaggaaatg tattactaaa agtaattgta gatggattca ttaactcaga ggattcaatg
     1441 atttccggtg gaagtttaat aaataatagt agttttatgt caaatataac aacacttgga
     1501 caaagttatt taatattaat aagtattatt gttttatcag ttgtatttgc ttcttcatta
     1561 atgttaatca agaagcctaa agaaatctta tcaaaaataa gttaggagaa aataatggat
     1621 atattagaaa taaagaatgt agcatatagt tatgcaaatt ctaaagaaaa agttttgtca
     1681 ggagtaaatc aaaaatttga acttgggaag ttttatgcga tagtaggaaa gtcaggaaca
     1741 ggaaaatcta cacttctttc cttacttgct ggacttgata aacctcaaac aggaaaaata
     1801 ttgtttaaga atgaagatat acaaaataaa ggatatagta atcatagaaa aaataatata
     1861 tctttagtat ttcaaaacta taatttaata gattatttat caccaattga aaatattaga
     1921 ttagtaaata aatcagcaga tgaaagtatc ttgtttgaac taggtttaga taaaaaacaa
     1981 ataaaaagaa atgttatgaa attatctggt ggacagcaac aaagagtagc tattgctaga
     2041 gcattggtat cagatgctcc aataatacta gctgatgagc ctactggtaa tctagacagt
     2101 gttactgctg gagaaataat taatatatta aagacattag ctaaagatag aaataaatgt
     2161 gtaatagttg taacacatag taaggaagta gcagattctg cggatatcat tttagaacta
     2221 agtggtaaaa agttgaaaaa agtaaataaa atgaatttgg aggttgaata atgataaaaa
     2281 atgcatttgc ttatgtaact agaaaaagtt taaaatcatt aattatcata ttagttattt
     2341 tatctatgtc aactttaagt ctcattagtt tatctattaa agatgctacg gacagagctt
     2401 caaaagaaac atttgctaat ataacaaata gtttttctat ggagataaat agacaagtaa
     2461 atccaggaac acctagaggt gggggaaatg taaaaggtga agatattaaa aagatatctc
     2521 aaacagatag tatagactcc tatgtaaaaa gaataaacag tgttgcagat ttagttgatt
     2581 atgatattat tgaaactcaa gagactcttg cgaatcaatc acctgaaaga gcaaagaatt
     2641 ttaaaagaac agttatgtta actggggtta acgactcaac aaaagaaaca aaatttgtat
     2701 cagaagcata taaattagta gaaggaaagc atttagaaaa tgaagataaa aataaaatct
     2761 taatgcataa agatttagct gaaaaaaata accttaaagt tggagataag ataaaaataa
     2821 aatctaattt atttgatgct gataatgaga aaggtgcaga tgaaacagta gaagtagaaa
     2881 ttaaaggtct attcgatggg cataatagcg gtggagtaag tgcagcacaa gaactatacg
     2941 aaaatacatt aatcactgat attcatacag ctgctaaagt ttatggtaat accgaagata
     3001 cagctgtata ccaagatgca acattctttg taaaaggtga taagaatctt gatagtgtaa
     3061 taaaagatct tgggaaatta gatataaatt ggagagaata taatttgatt aaaagttcat
     3121 caaattaccc tgcattacaa caatctatat caggtattta ctcaatttca aataaattat
     3181 tttttggctc attaatattt gcaggagttg tagtttcatt attattattc ttatggatga
     3241 atgctagaaa gaaagaaata gcagtattac tatcattagg tatatcaaaa ttagaaattt
     3301 ttggtcaatt cctaattgag atggtattta tatcaatccc cgcattcgtt ggttcctatt
     3361 tcttagctca atatacagct gacaagcttg ggaataatat attgaataag gttactggtg
     3421 atatagctaa acaaatagct aaacaatctg catctagcca attaggtggt ggggcagaag
     3481 ctgaaggatt taacaagaca ttatcaagtt tagatatcaa tgtattacct aaattcatga
     3541 tttatgtagt tatatttatg agtttagtac ttcttgtatc attgattatt tcttcattca
     3601 atatattaag aaggaatcca aaagaattat taattgacaa taattaaaat tttcggtgct
     3661 ttttagcacc aaaaatgaga gtgtaatata aaccgtgtaa gtaaccatca atcctaggcg
     3721 ggtggttgct tcacggtttt tatttttcta aaataagatc aagaggtgat tacacgatgg
     3781 ctagaaagaa aagaaatcct gatgctgaga agttagctga atccattttg aatacttatc
     3841 aacccgaatc tgtagaggat atgcaagatg ttttaaaaga tgtgtttggt cccttatttg
     3901 aaaaaatgct tcaaggagaa ttgaataacc atttagggta tgacgcccat tctaaagagc
     3961 caaagaaaca tgacaatcga cgaaacggtt atggcaataa gacgcttaaa acgagctttg
     4021 gtaaagtaaa cattgatgtt cccagagacc gggaggcttc ttttgaacct gagttgattc
     4081 ctaatagaaa acgagatgtc tccgacatc
//
LOCUS       DAIGSZ010000131         4070 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.136, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000131 DAIGSZ010000000
VERSION     DAIGSZ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.136"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            86..1435
                     /locus_tag="NOB31_002820"
     CDS             86..1435
                     /locus_tag="NOB31_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0974981.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="NOB31_002821"
     CDS             complement(1563..2153)
                     /locus_tag="NOB31_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCI0974982.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="NOB31_002822"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="NOB31_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCI0974983.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1176 a          744 c          789 g         1361 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtttattgag
     3781 aggtcgtgaa aaagccgctt agtttcaagt attaagaaat attttgtgaa aatggcttct
     3841 cacatttttg cataaatttg acttaatacc gagaaactgg cttttgaaca ccgtttattg
     3901 agcgtctata aactgacctg agtattagag aaacaaaacg gcaaagtagc tccatatact
     3961 ttgccgtttt gttttgaact aataccgaag agaagctgat caaacaacat ttcttttata
     4021 atatagattt tagacatata tatgatataa aaatagtttt cgcaaaaaaa
//
LOCUS       DAIGSZ010000132         4037 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.137, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000132 DAIGSZ010000000
VERSION     DAIGSZ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4037
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.137"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(243..392)
                     /locus_tag="NOB31_002823"
     CDS             complement(243..392)
                     /locus_tag="NOB31_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974984.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            854..1066
                     /locus_tag="NOB31_002824"
     CDS             854..1066
                     /locus_tag="NOB31_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974985.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1344..3143)
                     /locus_tag="NOB31_002825"
     CDS             complement(1344..3143)
                     /locus_tag="NOB31_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCI0974986.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3267..3863)
                     /locus_tag="NOB31_002826"
     CDS             complement(3267..3863)
                     /locus_tag="NOB31_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCI0974987.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1449 a          711 c          689 g         1188 t
ORIGIN      
        1 tatattaaat attatacaga taataacgga atattatcat cgaaacagct aacaaaattg
       61 tcataaaaaa cgagatggtt gatattagaa cttgtgtttt tgtttaggtc tagagataaa
      121 gagagacaat ttccaaatat atgtaatgaa tacaaaaaga cgtttgtcgc ggattaccgt
      181 tacaaacgtc ttttattgat tttccgagat ctcatcagtc gccatttgga atggttcact
      241 ccttatctag attcgtttaa tgctcggact gcttgttcga ttgtaatacc aaacgcaacg
      301 ttattttcgt tttgtgcatc aatcgccata aaacggttag aagttgtatc aaaagctacg
      361 cggtattgca tatttgtttt tgtaaacgtc ataaaattca tctcctttgt aatgtaattt
      421 agttcttgaa agtttccttt aaactttcga acttatacca agtttagcat cgtacgtttt
      481 ttgatgcaat taaaaagcat ttatcatttt ccttatttat tttttcttaa atggtttagc
      541 tattttcttt taatccgata agtagcccaa tcatcaaggt tacaaatact attgcttgaa
      601 tataaatcat atgctcacct ctttataaat aacttagcaa tataaagaaa aaaacgcacg
      661 aacaacatag gaatataaac aaacgttttt gtcacaacgt ctaagatcgt gttaaaaaat
      721 agttatctaa aaagcagaaa gatactcaaa ataaaaaata aaaaaatgga taaaaacgtt
      781 ttcaaataca aggtaatttg ttattataaa ataaagaaaa aacaaaataa aaataaagaa
      841 aagagggaat gaaatggtaa aagcagaagt aggaagatct tatatatgca aaccgatcgg
      901 agtatctcat gaactaatcg gctgtattga acgtacatat atcaacacgg ctgtcgtgta
      961 tgttgaaagt tatgaccaac gagactatca acttatcaat gaaagcaagt atcgcatgct
     1021 cgtaaaattc tgtgatatta gcgcacctgc tgaattggtt tcttaaacag tatttttgag
     1081 aattcgcaag aactccctta taatataaat aaagacagaa gggagcgaga agatatgcca
     1141 aaaagaaaaa gttcagggaa aatgggaatt attcttgcag tgatctctgc aattcctgct
     1201 attttagcta ttgttcgtgc gatgaaggaa tcaagagaaa gttaagcaca cattatgagc
     1261 gtcaaacaaa aaacgcatat acctgcggtg gcaggttatg cgttttttgt tgtataaaga
     1321 cttttttcat taacgatttt tgattagccg actcccaaaa caaaatttag cagtttatct
     1381 gaataagtga tttcttcatc tgtttgtttc acactttcat ttagtagtcc catctcatcg
     1441 gttatgatac catccacacc ataaaacatc atgcgactca tagcatctga atcgttgatt
     1501 gtccatacat atacttcttt tccgtcttgg tgggcagaat taatgaagtt acggttgatc
     1561 gtactatatt ccattgtcag aaaatcagca ggcgtcacag ggggcccaac aatattgaaa
     1621 ggtaagatgt agcccacata aaagtttggt tctgcttctt ttaaatctga aacggtttgg
     1681 tacgtcaaac tttgcaaaat atgatggttc tctaagataa ctttgcggta tttatggaca
     1741 aatcgttcga caaggtcatc cgaatctttt ttagaggtct tgatctcaat aagtaatttt
     1801 tggtttagct tatgtgcttt ttccaaataa gaatcaaaag aacaaacagg ggcttgcact
     1861 ccgttttcag taactgtaag atttgtcaat tctttcaatg taagatcctg tggtgttcca
     1921 tttacccctg ttaagtgacg aagatttgca tcatgcatca ctacgaaatg accatctttt
     1981 gtttcctgaa catccatctc tacataatca ggatgatagt ctctgcttgt tttttcaagt
     2041 gcttctaaag tattttgcgc cccattttgg gtactcacac ctctgtgaga gacagtcact
     2101 ggttttgtct gaacagctga agtcagataa tccatattgt aaagacagac gccaataccg
     2161 aaaaaaactg caaaaagagt caaaccagtg tttttcagcg cagagaaacg caagttgggg
     2221 gcttgtggga taaaccactt agggatctca ggcaagaagc cttcgtcatc catgaaatca
     2281 acaatgatat aaaaaatccc tacggtagac atcacgatat tgaataataa aatcccttgt
     2341 aaaagcgtca tagcaaacac agcgctgatc aatgcatagt ctgggaaaaa ttgttcaacc
     2401 atactttgtg ccaaaataac aacgatatat cctaaagaag aaaggagtaa aatcgtaccg
     2461 ccaatcacaa taaattggcc cgtgatggcc aaaagacgcg atttggtcaa tgaccagctt
     2521 tcccgaatgg ctgctcgaaa aggacgatct cgtagaatca tttccggtaa agcaaaaatc
     2581 agtcgaatcc caatatagcc aaggaaaata taaacgagta aaaaggaact gacgatgatc
     2641 caacgattag caaaaataaa atccataatg aaagcgggga tttttatttt tgacagtaga
     2701 tcagaattaa aacttaatcc gctgatcggt agaatcaata aaaaataagc aaggaaaaac
     2761 aaaaaagtaa tgggtctcac tttcttcagc tgaagtatcg tcaagtgtaa gagttgcttc
     2821 aaagagattg gttctttctt tttaataaaa aaaacactca tcaaaagaaa agtaaattcg
     2881 aaataaacta acagtaaaat cgtcatcaaa actacgatta acgagagtag aaccccagga
     2941 tgttgagaaa aaattgaagg aatattgtca taagacaaat agtcaattgc ccctcggtgt
     3001 aaaataaaac gggtcgtact gctcaataag ggtaaacaaa taaataaaat aaagccatgc
     3061 atcagcaaga catcacggaa ataagcttgt gttcctttta aaaagtccca agcattacct
     3121 aagctacgtt tcaaataatt catcctatca cctgctcttc acattgtagc gcaaatctaa
     3181 tgaaaaagga aagggtgcag tgtgttttgc agaccctttc ccagatttaa cattgtcaat
     3241 caatgactaa ttttacaaaa taaatattat ccaagaagac cacttagata ttgacctcca
     3301 taaatcaagg ccatactata taagaaaatc gacagtggtt tagcaatcaa aatgattagt
     3361 gtatatcgtt tcactgacat gtttgtcaat ccagccatca aacataacgc atcgtcagga
     3421 gcaactggaa gaaaaatagc tagagcaaac agcttctcaa aacggttttg attatccagc
     3481 cagccaatat atttgttata tgtcttatcg ctaatcatgg aaagtatgaa tggctttcca
     3541 taacgacgcc ctagcagaaa aatgataatc gaaccaatgc agattccaat atagttatag
     3601 ataaatccag cataagggcc aaatatcagg acaccagctg cagtactgat ccctccagga
     3661 atgattggaa taactacttg caggatttgg atgaagacaa aaataatcgg tcctaaaatg
     3721 atggaatcac ctactaatcc tcttaacgca ttcaaatctt tgaaaacacc taaattaata
     3781 aaataaatcg tcagcgcgat tgataggcct aatccgataa tggatatgaa atttatcagt
     3841 tttcgagagg cagcaatatt cattattcat caactcctta gaggttcttt gttaactata
     3901 ctttactaga aaagcaacta actgcgccat tttttgatat gacagaaaac aaacaatttt
     3961 gtaagttcat cataagtata aaagattgat ctcaaaaaaa catccaacta aagacttatt
     4021 taataacttg ttttttt
//
LOCUS       DAIGSZ010000133         4002 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.138, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000133 DAIGSZ010000000
VERSION     DAIGSZ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.138"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..210)
                     /locus_tag="NOB31_002827"
     CDS             complement(<1..210)
                     /locus_tag="NOB31_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCI0974988.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
     gene            complement(309..623)
                     /locus_tag="NOB31_002828"
     CDS             complement(309..623)
                     /locus_tag="NOB31_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974989.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(691..1185)
                     /locus_tag="NOB31_002829"
     CDS             complement(691..1185)
                     /locus_tag="NOB31_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974990.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            complement(1178..1492)
                     /locus_tag="NOB31_002830"
     CDS             complement(1178..1492)
                     /locus_tag="NOB31_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974991.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            complement(1708..3099)
                     /locus_tag="NOB31_002831"
     CDS             complement(1708..3099)
                     /locus_tag="NOB31_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCI0974992.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            complement(3084..3695)
                     /gene="mobC"
                     /locus_tag="NOB31_002832"
     CDS             complement(3084..3695)
                     /gene="mobC"
                     /locus_tag="NOB31_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HCI0974993.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(3699..3896)
                     /locus_tag="NOB31_002833"
     CDS             complement(3699..3896)
                     /locus_tag="NOB31_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0974994.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
BASE COUNT         1169 a          750 c          535 g         1548 t
ORIGIN      
        1 taaatcagat acataagccc atgtacccgt tcgttgtaaa taaagttctt cttgtaacaa
       61 ctcccatttt ctcttagaaa tcataatgac gccatcgttc aatccatttt tagaatccct
      121 agtaatttct atttcagaat ttgaatgaac tacttcttgc aacactttac ctatattttc
      181 tttgaagttt gttggagtaa tagtatccaa aatgaatacc tctcttctct atacctctat
      241 tatgaagtgc ccataaaata aagcaagcgt tgaggaataa ttctatcaac acttgcttta
      301 ttaagctttc attttgtagt ttgactaaaa ccaataatct tatttctaaa ctctcgaaaa
      361 acttcttgtg gttgataata gtctggatct atttcaaatg tttgtgagaa taattcattg
      421 aatttttcta ctgaaataat gattttacca ttcttctctc gactgttttc tattatttct
      481 gcttctaatt caaataaatc tagtgacgaa ctaaaatcat aaatcatgtc atattgaata
      541 aaaaaatcaa gaaaaagttg ctcaaactct tccttattta tcactaatgt ttcaaacgga
      601 acaactttat tttcctcagc cattctccca gttccatttt caaaaatcac aaaactgata
      661 ttaccttaaa aactactaac aaaataaaac ttataaagta aatggcaacc caactatgta
      721 accattctct ctacgtacta cgatttggta gtcctgcctt tcaatcggta attcataata
      781 gtaatttact gtttcttctt tgccactttc aatatactct ggattatcca atatcatatc
      841 atactcataa agttcttcac catccttatt ttcaatcgac cattgttgtg gacgtatcgg
      901 attttctgta tcatttataa gtgtataggt cacttgtaat acacgatcat gttgtgcaaa
      961 ttcatttctt ttttcggtca cttcaatatt tttaaatgtt agttcaaccc catctgcctg
     1021 ataagtttca cctattttta aatcttttgt tacaattttt attggctttt cttctggaaa
     1081 atgtctggct ttaattgtta gataacttcc aaaaagaatc aatcctagta gcactaaaag
     1141 aattccttta acgagccact gaaacgggaa gtaaacttta aacatctttt ttctcctccg
     1201 ttttgtattt gttttttaga gaatacgata acttttgatc aatgtcatcc agcttttcaa
     1261 ttacttcatt acttatcatt gattctagtt ctgaaatttt ttgttcaaat ttaatgcttt
     1321 caggatcatt aaatttatta tttgatggac tagctaacac tggtaaattt gaaaccataa
     1381 cacgaaacat atttgccttt gaaccaaaaa ttcctttgtt ttggttgtaa aaattgttga
     1441 atatttcttt agtttcttct gaagccgaga ctttaaaata tggatagttc atttttttct
     1501 tccacctttc tttttttggg agggagtctg tagggagctt gctccctcag agatttaccc
     1561 gccatctgac ttgccagaaa gtagcctagc gtgagcgggg cggattgact ggcaagtaga
     1621 tgggtagctg gcgtatgtcc taaaaactgc ttctttccaa gcaactcttc ataggcaaaa
     1681 aactggaaag tccactaaca agcccattca gaattccatt tcaaaatttt gttgcctttt
     1741 ttgctgattt tcaatcattt gttgtgtgaa ttcataatcc tttttagcac gatacatttt
     1801 tacatcgtca ttcattatgc gactgatttg atagtgaatc tgtttagcag aaggtgtatg
     1861 agaacaattt tcaaaaccct ttgccggtag aaataactct ttctgatcag tctttttaat
     1921 agaaattgtt ttacttttcg cactacgtaa agtttgagga ttcacatccg tatgaagttt
     1981 aatcgtgtat tcttgatcat cttctaaaga cattgtattt acaaaatgct tgtctacctc
     2041 tcgcaagaag tcatcatatt taatgaattt ttcatcgcct tcacggtcgc taaattgctt
     2101 ttgtgcgatg gaatctaatt ccacaaacgg tacatttaac tcaccagttt tgtaatttac
     2161 tccactaatt agcgacataa cttgctctct ttccatatta aaaaaatttt ttatatgtga
     2221 ttcttctaaa ttcttttcaa gttgttcaga aacagattca aatgaatatc ttttccctaa
     2281 ctttcttgca ctaaaagtac gttcgacata ctgacttttt tcttttctag attgtttatc
     2341 tcttcctaaa gtaattaact cacctctacg ctcatagaaa tttacacctt gtttgtaaag
     2401 aacatagcca agtttgttat ttgtttttga aaattgataa acttcaatgt tatattcttt
     2461 tgccaaatga tccgaaaaat cttcaaaaga attcacttcg catttttcca acgttgcttc
     2521 gatcgcattt tgcacaaact cttgataatt aatttttcca tatttcatct tagaaggatc
     2581 gtttgaataa agattggttc tcttttctaa gttttcatag tactcattat tcactgattc
     2641 aagaccatgt tcattgagga cttgatcgtt aatttttcgc attagttcta aatctttagg
     2701 gtcaatacgc aaccttttac atgtttccat gttaatatta ttaatgacaa gatgactatg
     2761 aaaatgatct ttatcattgt gacttgcaac aatgatttgc gaatttggaa aagctttctc
     2821 tgcaaattcg acagctattt cgtgcatttt atcaatactt aactctttag aagtactctt
     2881 atcaaacgaa tgaataacat gaaacgcttg tgctatatct ttagatttat tcatcttggt
     2941 acgtactaaa ttcatttctt gcagtgcttc ctcactatca tcactacaat ttattcctga
     3001 gactgcaaca catttttctt tttttgaagg attagctgca tattgtaata gcgaggataa
     3061 atttttcttg cgtcctttcg atgttatagt agctcccaaa gttgtttcac ctcatctttt
     3121 aaacttgcaa taatctgaat tgagtgaatt aaattccgat caactttttg ggaatactct
     3181 tctttcgtac ccggtctagt ttgcttttct atccaatatt cgaaatattc tttttctact
     3241 tctgataatt taaaaaaaga gggggcactc cgattggact ccaaaaaaat gtcatctgga
     3301 taactaatca tcaacttttt tgctatgcta ttcgcaagtt catctttaaa aatgttgtaa
     3361 cggctagcat caaaactaaa atgtaggctc ttttcttttt tatcttcaga ttcttctcta
     3421 aaatatttag caatgatatt taatgccttt accgcttgat tcaaattgtt accaatttga
     3481 tttaactgtt tggttaaaac taccctatca tcttcagcta acaacggcgg ttcatatttg
     3541 agtcccttta accgctcacg gcaaacgtct gctctagaaa ttcccctttg ttttgcaatc
     3601 aatgtcagtt caagataagt ctttttatcg acacgaaaat ttaaggcctc actatgtttg
     3661 cgattttttt cgtacatttt ttgtttatca tccattgatt atcccctcac atttttttct
     3721 agagagcaac atttgaaatt gctctctatt tcatttttca tctttaattc ttcttgaatc
     3781 atcagttcaa tataattagt gaccgtgatt ttttcatttg ttgcgttctt tactgattca
     3841 cataattcgt caagttctaa gaaatcatgc gtactaatct ttagaattaa ttgcatgaca
     3901 atccccccct tttatttctt aataaattat cgaaaagtgg attaggatca ttaagtgtat
     3961 ctctgaataa ctcattgtct tcataagtga atcttcgtct tg
//
LOCUS       DAIGSZ010000134         3872 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.140, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000134 DAIGSZ010000000
VERSION     DAIGSZ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.140"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            123..1292
                     /locus_tag="NOB31_002834"
     CDS             123..1292
                     /locus_tag="NOB31_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0974995.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
     gene            complement(1617..2936)
                     /locus_tag="NOB31_002835"
     CDS             complement(1617..2936)
                     /locus_tag="NOB31_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCI0974996.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(2933..3586)
                     /locus_tag="NOB31_002836"
     CDS             complement(2933..3586)
                     /locus_tag="NOB31_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCI0974997.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT         1317 a          614 c          453 g         1488 t
ORIGIN      
        1 ttttacactc tctattatga tagcgtaaaa tattttgtgt aaatagaaat ttagggtaga
       61 aaaaaaagtc cattctgtaa aattaaagtt accacacaga aattttatag gaggactttc
      121 tcatgactaa atttactata gaaattatgc aaacactact caataaaggg gatttagatg
      181 aattatttca ggatcattta gagcgagcga ttaattcact tctacaagca gagctaactg
      241 cttttttaga ttacgaaaaa tatgatcgaa atggattcaa ttcaggaaat tcccgtaacg
      301 ggaattattc acgtacattt aaaacagaat atggcgagtt gaatttaact attcctagag
      361 atcggaatgg cgaattttct caacaaacac taccagcata taagcgaacc aatgattcat
      421 tagaaacgac cattatccaa ttatttcaaa aaggcattac tatggctgaa atctccaaat
      481 taattgaaaa aatgtatggt caccactata cgccacaaac aatctccaac atgagtaaat
      541 tggtggctga agatgtttta gcttttaaag aaagaacgtt agaagccaat tattccgtta
      601 tatttatgga tgcgacgcat atccctgtga agcgacagac tgtttcgaag gaagcagtgt
      661 atattacgat tggtattcgt ttggatggaa ccaaagaagt tcttgggttt actattgccc
      721 caactgagtc tgcttatatt tggaaagaag ttcttcaaga tcttagaaaa cgtgggttag
      781 aagaagtttt attagtagtg acagacggat taagctgtat tgaagaaagt atccatagtg
      841 tgtatccgaa tgcccaattt caacaatgtt gtgtgcatgt atctagaaat atcgctcata
      901 aagttcgtgt tcgaggtcga aaagaaattt gtgaggattt caaattggtt taccaagcga
      961 attcaaaaga agaggcattg gatcacatcg actttatgac taggaaatgg aaaaagcagt
     1021 atccaagagt cgtcaattta ctcttgaatc ctgccctatt aaccttttat aatttccctc
     1081 acgccatcag acgaacaatt tattcgacga acctgattga aggctttaat aagcagctaa
     1141 aacgatatac tcgaagaaaa gaacaattcc ctaatgaaga atctctagag agattcttca
     1201 tttctcaatt taatcaatat aaccaaaaat ttttaggtag aattcacaag ggatttaaag
     1261 aaattcagga tacattagag tcgatgattt aactgtaatt aacagaatgg attttccatt
     1321 tacatataat tcttgacgct accataatct aaataaccat catattcatc tactacttat
     1381 ataattgagt tttattaaac tttttaagtt tctattctat caaatattta aacaatctct
     1441 gcatccgaaa agactacctc gtatagtttt actaacaata tttttattag cgtgttcaaa
     1501 tcctgatttc ttgtatcaat tattttctgt tcactttcaa taagaaaaaa gtctttactt
     1561 ccatggataa taataagtct ctatttttca ataactattg caaaattata tcttaattaa
     1621 gaaaatattt ttattttaaa gataaaaaat tcttcatcct gcaatacttt atattctata
     1681 ttgtaattat tcagaatatt acttacaata tataaaccta atccattact attttcctta
     1741 tttaaatcaa atttaacatc aaatatttta tccatattcg aaattttatt gttaccgtat
     1801 gaattctcta tatataacca atcattaact atcccaatat taattacccc atttacatca
     1861 gtatatttta ccgcattact aatcaaatta gatagaataa tctttaaagc tgtttttcct
     1921 atataaacat tctcgtctaa tatataatta ttgacagtta ttttcttttg atttgctaat
     1981 atttcatact tttttaatat gtcttctaat gtatcattta ttttcaaata ttcttcatca
     2041 ttattcaaat tttctataga atgaactgat aatatttgag aaatattttt tgttaaacta
     2101 tcaacgattt caatacattc attaatataa atatctcttt ctttatattt tccaatattg
     2161 tatttcatgt tttccagtat tattttaaga ctagcaagag gggttttaag ttcatgggat
     2221 gcacctttaa aaaagtcata ttttaacttt tctaatttta aaatttcttt atttttaaat
     2281 tccaaatcgt caattgttct taataaagta gaatacaaat cattaatttg ttgttttaat
     2341 tctccaactt catcattaga gctaactttt aaactcattt ttttatcaag tttcatcatt
     2401 ttatcagtaa caatttttat ttcttgtata ttatttttta ttgattttgc ataaattaaa
     2461 gaaataatag cagaaaataa aattgatatt aataaagaat atggtaaaaa tttaaggctt
     2521 aaatctttcg catctttttg catatcagct gtagaaacaa attgtagatt tgttttttta
     2581 ccatcattaa gctttatttc tctttcttca attatcaaag aattactatc actttctaaa
     2641 ttaacattta tattatcttt gatttgtatt tcattcttat tatttttttc ttttatgaat
     2701 acttttattt cactactctt ggaataaaac tccaaagttt gttctatata ttttatttct
     2761 tttccattca tattactaga aatttcattt gccatattat gaatcttttc ttttctcgtc
     2821 tccaaatatg ttttaggaaa gataaaaaaa attaatgaat gaactaatat aattattatt
     2881 ccaagaacag aaaatatttg tatgaacatt tttggaaata tctttaattt tttcattttc
     2941 tctccaattt atatcctaca tttcttatag tagttataca gtctaattgt aatttttttc
     3001 taagttcttt tatatataca tctattactc gatcataagg agtttcttcg ctatctttcc
     3061 atacataatc aataatttgc attcttgtta acacttgtcc attattatcc aataaacatt
     3121 ttaatacttc tagttctttt gcatttacat ctatttcttc accatttatt ttagctgtat
     3181 agctattaaa attaaccgat agatccttat attcaaactt ctctaaatgt ccataattct
     3241 tcttaattaa agaatctatt ctagctttta agaccggcaa tgaaaatggc ttttctacat
     3301 atccgtctac taaattagta aatgcatcaa ttttatattc ttcatcacta aatgcagtca
     3361 agattagaat tggtaaattg cttttctttc taatttcttt caacacttct aaaccattta
     3421 taaaaggtat ctgaatgtct aagataacca aatttatatc gctattaaat tttgacaagg
     3481 cttctcttcc atctttagct tgaataacag tatatccaaa ttctgaaaga tattcactta
     3541 ttccctctct tatcatatta tcatcttcaa cagttaatat tttcatatat acctccactt
     3601 aagcctatac actagatatt atacagcata ttatggctct ataatatcta gtgttggtga
     3661 cgccttctgt tgccaatact ttttcttttt tttaataaat gcaaacagac accttgaaat
     3721 cctttagaaa aaaggcttct ataatatttt gtgttgttgg aaaatcgaag gcgattttct
     3781 actaacactt tttcttcgtt tcaactcaaa aagagactca cttttggtaa aatttagtcg
     3841 accaaaacat caccctacca aaggagtcgc tc
//
LOCUS       DAIGSZ010000135         3843 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.141, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000135 DAIGSZ010000000
VERSION     DAIGSZ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3843
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.141"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            299..415
                     /locus_tag="NOB31_002837"
     CDS             299..415
                     /locus_tag="NOB31_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HCI0974998.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            431..2350
                     /gene="tet(M)"
                     /locus_tag="NOB31_002838"
     CDS             431..2350
                     /gene="tet(M)"
                     /locus_tag="NOB31_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HCI0974999.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2469..2636
                     /locus_tag="NOB31_002839"
     CDS             2469..2636
                     /locus_tag="NOB31_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HCI0975000.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(2696..3049)
                     /locus_tag="NOB31_002840"
     CDS             complement(2696..3049)
                     /locus_tag="NOB31_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0975001.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            3554..>3843
                     /locus_tag="NOB31_002841"
     CDS             3554..>3843
                     /locus_tag="NOB31_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975002.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILL"
BASE COUNT         1295 a          592 c          751 g         1205 t
ORIGIN      
        1 caatttgatt tggtacttga aaagaacggg agtaattgga agattataga ataacaaata
       61 ttggtacatt attacagcta ttttgtaatc acgtactctc tttgataaaa aattggagat
      121 tcctttacaa atatgctctt acgtgctatt atttaagtat ctatttaaaa ggagttaata
      181 aatatgcggc aaggtattct taaataaact gtcaatttga tagtgggaac aaataattgg
      241 atgtcctttt ttaggagggc ttagtttttt gtacccagtt taagaatacc tttatcatgt
      301 gattctaaag tatccggaga atatctgtat gctttgtatg cctatggtta tgcataaaaa
      361 tcccagtgat aagagtattt atcactggga tttttatgcc cttttgggct tttgaatgga
      421 ggaaaatcac atgaaaatta ttaatattgg agttttagct catgttgatg cgggaaaaac
      481 taccttaaca gaaagcttat tatataacag tggagcgatt acagaattag gaagcgtgga
      541 caaaggtaca acgaggacgg ataatacgct tttagaacgt cagagaggaa ttacaattca
      601 gacaggaata acctcttttc agtgggaaaa tacgaaggtg aacatcatag acacgccagg
      661 acatatggat ttcttagcag aagtatatcg ttcattatca gttttagatg gggcaattct
      721 actgatttct gcaaaagatg gcgtacaagc acaaactcgt atattatttc atgcacttag
      781 gaaaatgggg attcccacaa tcttttttat caataagatt gaccaaaatg gaattgattt
      841 atcaacggtt tatcaggata ttaaagagaa actttctgcc gaaattgtaa tcaaacagaa
      901 ggtagaactg tatcctaata tgtgtgtgac gaactttacc gaatctgaac aatgggatac
      961 ggtaatagag ggaaacgatg accttttaga gaaatatacg tctgggaaat tattggaagc
     1021 attagaactc gaacaagagg aaagcataag atttcataat tgttccctgt tccctgttta
     1081 tcacggaagt gcaaaaaaca atatagggat tgataacctt atagaagtga ttacgaataa
     1141 attttattca tcaacacatc gaggtcagtc tgaactttgc ggaaaagttt tcaaaattga
     1201 gtattcggaa aaaagacagc gtcttgcata tatacgtctt tatagtggcg tactgcattt
     1261 gcgagattcg gttagaatat cggaaaagga aaaaataaaa attacagaaa tgtatacttc
     1321 aataaatggt gaattatgta aaatcgataa ggcttattcc ggggaaattg ttattttgca
     1381 aaatgagttt ttgaagttaa atagtgttct tggagataca aaactattgc cacagagaaa
     1441 aaagattgaa aatccgcacc ctctactaca aacaactgtt gaaccgagta aacctgaaca
     1501 gagagaaatg ttgcttgatg cccttttgga aatctcagat agtgatccgc ttctacgata
     1561 ttacgtggat tctacgacac atgaaattat actttctttc ttagggaaag tacaaatgga
     1621 agtgattagt gcactgttgc aagaaaagta tcatgtggag atagaaataa aagagcctac
     1681 agtcatttat atggaaagac cgttaaaaaa agcagagtat accattcaca tcgaagttcc
     1741 accgaatcct ttctgggctt ccattggtct atctgtagca cagcttccat tagggagcgg
     1801 agtacagtat gagagctcgg tttctcttgg atacttaaat caatcgtttc aaaatgcagt
     1861 tatggagggg atacgctatg gctgtgaaca aggattgtat ggttggaatg tgacggactg
     1921 taaaatctgt tttaagtatg gcttatacta tagccctgtt agtaccccag cagattttcg
     1981 gatgcttgct cctattgtat tggaacaagt cttaaaaaaa gctggaacag aattgttaga
     2041 gccatatctt agttttaaaa tttatgcgcc acaggaatat ctttcacgag catacaacga
     2101 tgctcctaaa tattgtgcga acatcgtaga cactcaattg aaaaataatg aggtcattct
     2161 tagtggagaa atccctgctc ggtgtattca agaatatcgt agtgatttaa ctttctttac
     2221 aaatggacgt agtgtttgtt taacagagtt aaaagggtac catgttacta ccggtgaacc
     2281 tgtttgccag ccccgtcgtc caaatagtcg gatagataaa gtacgatata tgttcaataa
     2341 aataacttag tgtattttat gttgttatat aaatatggtt tcttgttaaa taagatgaaa
     2401 tattttttaa taaagatttg aattaaagtg taaaggagga gatagttatt ataaactaca
     2461 agtggatatt gtgtcctgta tgtggaaata aaacacgatt aaagataagg gaagatactg
     2521 aattaaaaaa attccccctc tattgtccga aatgcagaca agaaaattta attgaaataa
     2581 agcagttcaa agtaactgtg attacagagc cagacgcaaa gacgcagagc cgataaaatg
     2641 agattaatac aatctcattt tatcggctct ttccgttatg tatggattct tttaattagt
     2701 cttcgatgtt tcttgcttcg ttgataccgc tggctaaaga ttccattaag gatagttctt
     2761 tgtctgtaaa gctatccatg tatttctcta tctgtaatcg tcgggtgctt tttaccaagt
     2821 tattagcagg taagaaaaat tcatcaacgg aaacatgaag taacgataca aggtcataaa
     2881 gaacttgtat gctggggtgt tgccctttat tttcaatatt agttaagtac cgtgggtcaa
     2941 tttcaatcaa tgctcccact tgttcacgag ttaaacctcg tttcaatcga gcttctttaa
     3001 tggctaaacc aaaggctcta aaatcatatt tatcttcttt tttacgcata gtagaccacc
     3061 tctatacatt ttattgttcc tactgaatta aaaacaggta tagaaaaacg tgttatatgg
     3121 tttataggtt tatatttaat aaaaagcact actaaacgcc aataaaaaaa accgttatat
     3181 ggtagtgcta tttacgctgt taaaatattg tatattactt ccaaatggcg gtttgttgga
     3241 ggtcaacgtc gccatgaagt acatcatata caataaattt ccttacattg ggttcttgtc
     3301 aaaaaaagtc gtctatctgc aatagataag tacgtccacc aatgtggttt tataaatcat
     3361 atagatagaa taacagaagc atgtaaacag agaaataaat ctgtttatat gcttttttgg
     3421 ctattcagaa cttttttaca aagtttattt atcagtaatg caacaaatcc ccctttcaca
     3481 ttgggactaa gagtgaaagg agataaacga gcaaggctca cttcctttcc tagacagaaa
     3541 gggggtgaga aacatgaaac catcttcttt tcagaccaca atagaaaatc agtttgacta
     3601 tatctgtaaa cgtgctatgg aagacgagcg aaagaattat atgctttatc tttcaaggat
     3661 tgcaaagcgt gaggtgtcct tttcggatgt tggcgattat cttgttagcc agtttgcgac
     3721 aacagataac tattcaactg actttcagat ttttacactc aatgggttat cagtaggcgt
     3781 tgaaaatgat ttgttgagtg aagcattacg tgagttgcca gacaagaaac gtgaaattct
     3841 act
//
LOCUS       DAIGSZ010000136         3772 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.142, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000136 DAIGSZ010000000
VERSION     DAIGSZ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.142"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(557..1597)
                     /locus_tag="NOB31_002842"
     CDS             complement(557..1597)
                     /locus_tag="NOB31_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCI0975003.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSSYSEAQQTVQTIHNAKRKAEELEQTIVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1945..2271)
                     /locus_tag="NOB31_002843"
     CDS             complement(1945..2271)
                     /locus_tag="NOB31_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975004.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNYKPKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2258..3061)
                     /locus_tag="NOB31_002844"
     CDS             complement(2258..3061)
                     /locus_tag="NOB31_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCI0975005.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3412..3702)
                     /locus_tag="NOB31_002845"
     CDS             complement(3412..3702)
                     /locus_tag="NOB31_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HCI0975006.1"
                     /translation="MSINTFVYSHPINVYIIKYLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
BASE COUNT         1143 a          620 c          540 g         1469 t
ORIGIN      
        1 ttgcgggtaa taccgtaaca ctgaagggca cgcattaagg cgtcatctta atgctttcct
       61 gtaggacact gacggagatt accagtctcc cgagccttac aggggccttt cttttttttg
      121 tattttcaat tatcacaatt tatcgtccaa aagtgcagaa cgaaaatcaa ttcatcacaa
      181 gcatatcaga caattaaatt taaaacaact aaaaatatac aaaaaagtgt aattgaatat
      241 tagcagcact gcctgaaaag aagtaatatc aggcttttca gcttggggaa ataagtgaat
      301 tacctctctt catgaattat tataactcaa aaaagcacat atgcaaacac tagttcccta
      361 tttttttgaa tgaaaaataa ctaaaatatc taacgattat gactttaaaa cctacgtttg
      421 tgattgtttt cataaacttt taatctaaaa actccggaat aataactatt tatttgtaac
      481 atttgtaata aaattaaaat cataaaaaag ttctaattta aaattgatca tttttatagt
      541 gatcgctttt tatcaactac tctagccaat tttccgtact aactgttggt aattcgttaa
      601 atgtttctct ttgttcgttt gcaagctttg ccgcaatagc tttttcgaca aaccaatttt
      661 ttacataaac gaaaattaga ttctgcaaat tgtttacttt ttcagttttt tgtttttgat
      721 aagctttcag taaagtcata tataatcctt tgtcagcatc aattccataa gattcaagtt
      781 cttcataaac aacaatagtt tgctctaatt cttcagcttt tctctttgca ttatgaatag
      841 tttggacggt ttgttgagct tcactgtaac ttgaagaaaa tgtttttatc aagttcaata
      901 cattttctgg tacaaatgta tttatactgt cctctttcat gatgtcgacg aagttatcta
      961 gtaaaacttg attttgtaac tgatcagttt cagtgtctat tatgtgtcta ttagtgtcta
     1021 tagaattaga atagaataga ttgtctgcga ttttcgcaat tacggttgag tccttgatat
     1081 gactggattt tgccgtattt gcgattttcg caattacggt ggtatcattg atttctcgcg
     1141 gttttgccgt atttgcgatt ttcgcaatta cggtggtatc agtattgtct tcctcttcca
     1201 tgattttaaa gacgtcttga ttcgttactt ctggcttgcc taagtacaat aaattaggca
     1261 tagattcaat cttaccatca cgtttattta ctcttcctct cttctgtttc agaagacctg
     1321 ctttttctaa ttcctttttg attttagata ctttaccttc gcggcattgt aacagtttca
     1381 ttaattcttc aactgtgaat atgaagaata tattatcatc agaatctacc cagttatttt
     1441 tgactgaata atcaaatcga tctttaagta gcatataagc aatttttgca tcatttgata
     1501 gatccatgta tttttcgtta gtaaaaaata ccttaggcat ttgataatat ttttcacgat
     1561 aaatttcttt tgatttgtaa taattaaaat cattcatagc caatcctctt tctgtaggat
     1621 agcgttttgt tcaaaactgt gttacaatga attaaacaaa tatatctatc cactatatat
     1681 tttctactgc tgataagtcg ccaaactttg ttaaagcagt agtctttttt tatctttttt
     1741 tagtttacct taaaaaataa attaaagcaa accgctctat ttcaaggttt aagctcatat
     1801 caactatatc acgatattac aataacatta tatcacgata ttgcgatatt acaatatgaa
     1861 gataagcgac ttatcagctt tgatactact gctttttata aaaaaaatat cacgatatta
     1921 tgatatcgtg atattgaatg taaattaaat tttattttgt ttctttgcta gtttatatcc
     1981 ttcaatcaag tattcttcag gtatggattt taatagcgca tcttctataa cgtctggttt
     2041 acttttgtct gattcagcaa tagtcgtcca atatttgagt gctgacatta gaattggatt
     2101 tatgcgaatg ctatctgctg ttcttacact acttccttga tcttttatga ctttacttat
     2161 atttttcttg gttaattcga tttcttctac ttcttttggt ttgtagttct ttttattttt
     2221 atttcctagt agtctactta ctgcagcttg actgcgatta tcttctgcca tcaaaatcac
     2281 caacttcttt taaatattct tctgtaaatg ctttatagtc atcttcagct gttgagggtt
     2341 tattaaaatt gattagatct gatccagcag cttgcgcttc gtcaacggtt attgtcctac
     2401 gaatataagt tttgaaaatt tttgcaccaa tgactctaga aatttcggtt gctgcagacg
     2461 tcatttcttt agaaatgtta taacgcttat tatacttagt aaataggact cctcgtactt
     2521 caagcttgtc gttcgtatat tcttttaccg tttcaatagt ttcacttaac tttattagtc
     2581 cttttaatga gaaatacgca gcttcaactg gaatgataat ttcatcagaa acagtaaatg
     2641 cgttgactgt aagcattcct aaacttggtg gacaatcaat tataatataa tcatagttgt
     2701 ccttgattgg ttgaagtact cttttaagcc tgtgttcact tcctacttga gtaaattccc
     2761 tttctgcaga agaaagggct atgtcggctg gcaaaacatc aattccttta tagtccagaa
     2821 tagcatctgt aatgtcagcc tcccctttta atacttcata aattgtaggt tggtttgttc
     2881 catctatatc gaaacctaca ttatctgtag catttccctg aggatcaatg tccactaaaa
     2941 gtacattttt accgtaaaca aatttcaaac atgctgctaa attaacgcta gtcgtagttt
     3001 tagaaactcc acctttttga ttggctactg acaatattct tgccattaaa atatccccca
     3061 ttcgtcttat attataatat aattatatca tgatattgtg atattgcaat atcgtatttg
     3121 cattatattg taatattgtg taattatttt gttttaaaga tatatatcgg ttcggatata
     3181 aagatcattc atatgttatt cgaaattaaa ataatcactt tttttaattt aaaatttttt
     3241 actaatgata agaaatatgt tttgtgagca gcaactagaa taatttaaac attactaaac
     3301 tgtctatatt gttactaata attcccttct tatagtgcat tttcttagaa aaaacaatat
     3361 tacgatatca tgatattaag atatcgtaat attatacaat tgtgattgat attatatatg
     3421 tttttttatt tttttatcat gtttaatctt gaaggaatca tattcttttt ctaaagacag
     3481 gagcttttca taaacatcag acatgttcaa actagaggcc aggcttaaat cataaacgaa
     3541 tgaagcaggt aatgatttta ttctacgttg tcgggttatc cagcttgcaa ccgttccttg
     3601 tgggtaggca tataactcac aaaattgttc tacagtgatt cctaaatatt tgataatgta
     3661 aacattgatc gggtgcgagt aaacaaatgt attgatggac atggtgcgta agcctacttt
     3721 cttttattat tgcgtttgca ataatagttt aacacacgca ttattctagt at
//
LOCUS       DAIGSZ010000137         3638 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.143, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000137 DAIGSZ010000000
VERSION     DAIGSZ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.143"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            951..1037
                     /locus_tag="NOB31_002846"
                     /pseudo
     CDS             951..1037
                     /locus_tag="NOB31_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            1597..1815
                     /locus_tag="NOB31_002847"
                     /pseudo
     CDS             1597..1815
                     /locus_tag="NOB31_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            2075..2329
                     /locus_tag="NOB31_002848"
     CDS             2075..2329
                     /locus_tag="NOB31_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCI0975007.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            2330..2647
                     /locus_tag="NOB31_002849"
     CDS             2330..2647
                     /locus_tag="NOB31_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCI0975008.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            3206..>3638
                     /locus_tag="NOB31_002850"
     CDS             3206..>3638
                     /locus_tag="NOB31_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975009.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNM"
BASE COUNT         1336 a          497 c          589 g         1216 t
ORIGIN      
        1 gtatgaataa aatttagttt taaaattaaa gataattaag tactaccagt gtcaaaacaa
       61 aaaataaatt aagaactacc ttatgcatat aaaacatact accattacta gtaatatata
      121 ctaccttatt tcagtagtat atattatatt cttcttataa gacaaggctt taggctagaa
      181 aacaatagat tatatactac taaaaaatac aataagtact accaatgtca gatatatata
      241 ataattatgt actaccatta aaattaactt atttaataag atactactgt gttaatctga
      301 aaaaaattac tttaaagtag ttacatacta cctgttaaat tagatactac cattaatact
      361 taaattagat actacctata tttatattaa gtactaccgt tctaggaata agataataaa
      421 aaaaaactac caaattgcaa ttaaatacta cttaaaatgt aaaaaataag aactacccaa
      481 attaggtagt tcttaataag agaatatcag ataaatttgt acaagtcata aaaaaattaa
      541 tcttaaattt ttaaatatat atacctgtta attataaact actttattta ggtagtacat
      601 aattaacaga taaaactaca tgcttgtagt ttgtctagct aatgagttgc atatgattta
      661 tataaaggtg tgcagcataa cttagttgaa gttaagagaa tagaataaat attttttgtt
      721 ttgctaataa ttaaacacta cctaaatatg gtagtgttta attatataat attcattttg
      781 ttacaaataa tcgtattata aaagcataac aattgggata actatttttt agattattta
      841 agtactactt aaattaggta gtacttaaat tttggtttaa ggtagtaggt aattaagaaa
      901 taatatatat cttcttttat aatagaaggg gagaggccta gttaaaaaca gcgacaatta
      961 ataacaatgt atttaatgct tcacaaaatc catttggtgg acaatgcatt gttattagcg
     1021 atgatctacc gttctaagta gttttttcta ttggttgcat tcgtgactaa ttatggtata
     1081 attatgagta acaaagaggt atttcattat atcatcaaac cccatcagcg tgtaggctga
     1141 tggggttttt tttacgtttc tatattatag aattaactgg taggcttact gtcttttttg
     1201 gcaattttgc aatcaagcca cttgcagatg tagtgtgcag ttacctctgc aaatggcttg
     1261 attgcaaaaa caaaatcaaa aaggtatttc attatatctc ctcctcccct tgccagatta
     1321 ggccggggta gcagacagca aaactattat aacataactg aaatacctaa atgacatata
     1381 cagatatgat aatttatgta ttgatttttc taacaaaagc acatatttta atatatacta
     1441 cctattttag gtagtatata tttttagata caatatcgat cagttttgag gaaatgaaat
     1501 tctagatatt ttttgctaca tagagttact ttcaatattt tttaacgtaa ttaggcagaa
     1561 gtcactcatc ctctataggt ttgtgatgaa attgctattg atccatttaa gtaagagcaa
     1621 aaaactggag gtttatcagg taattggtct aatggattta agtatgcggt caccgtgtat
     1681 agagttgctt atgagattca agaaaataaa gttattccag tattgctata tggaacacat
     1741 aacaattttt atgaattagc cgagaacact cgcaacttta ttcgtgtaga tgaatcggct
     1801 tcggttgagt tataacttta gctatatcaa tcaaccgacc gacatatgtt aaatctatat
     1861 ataataaaaa tacctactta aatggatgtt aacggaagtg tatggtgagt agttcactcg
     1921 tattttgata tcgtttgtat atgttttcag cgttctaagt ggcttatttt gtccaataat
     1981 aatatggagt ggaatccctt aagaaacacc gttggcaatt gtcgttataa catgttataa
     2041 tttatttatc aaaaactaaa agaagtgtga taacatggga aaagaactaa aggttagaaa
     2101 gatcggcaat agcgtgggag tgatccttcc aagctctctt ggattaaaaa gcggagacac
     2161 tatccaagcc aaacaagaag gcaacttatt catattagat actactcaaa tagcaaaaga
     2221 acacgatcgc aaattgattg aagaaagttt ccaagacttt gagaaaggtt taacagtttc
     2281 agaaattgaa atggtaaaag ctttcggaaa atacggctgg agtgaataga tgaaagagta
     2341 cacgctagtt tattctaaaa gtttccagac cagccttgaa acgataatag aagaatggga
     2401 aaatgagctt gctctttctc cagccagcat aaaaagattt gtaggtgcga tccagaaggc
     2461 tttagaacta accaaaaatt ttccaactat gcatgaggaa gtttccgaaa tctatggaat
     2521 ggatatccca acatatcgga tcgtgatcgg caaaagctat gccttatttt atcggatcga
     2581 ccatgaaaaa aaagagatac ttgtaggacg tattttccaa tctaaacaaa tgaaactagg
     2641 cttttaacaa taattaggca aaagtcgctc atcctctaca ggtgggtgat taatgccgct
     2701 cgatatggtt gttaaccgtc ggttactcga agattgatat ataagactta gtaccttttt
     2761 attttgctcc atgttatggc cgaaggtcta aagatacaat cattagtcta gagaaaaatt
     2821 aagaaccgta ggaactacgg ggatcgcttg gtgaataaga gacactgcta ttagtgaaaa
     2881 aataagatat caagtacgct ctattcccaa aaatttcgtg actttactca tgagaggttc
     2941 aagtagtata tttttaatca aaattgacgt aacttttaat aaatactacc taaataaggt
     3001 agtatttatt tttgtgtttt aaaagaggaa gtccaatata tctatgggaa acttcttaaa
     3061 tattatgttg gtacatgaaa atatacatcc ctgctagact atttacaaca ttttactttg
     3121 tacgtattct tgttttaaaa ggaatgggat aaaatatagg tacaataact atttgatgct
     3181 aaatataatt aatggaggag agatagtgaa catacttaat gaaaaaagat atgtatggtt
     3241 tgctggtaaa aaatatatta ctactttcaa aagattatcc gagttaatgc agcagactgt
     3301 taaaagtgct atgcctgaag gatacaagtt taattttgtt caatcttcag tatctactga
     3361 aagtatctat ttttcaattc tttctgagag taggcttttt cattttagaa taagttctca
     3421 tgtaaagaaa actgatgttg atatatatac gttccgtaca aataattata aaaatttaaa
     3481 tgatttgagt agaagtatca gtgaatatct caaggggaat agctatctca agattcgatt
     3541 ttcacatata ttaattttac taccatattt gaatgagaat ttcaccctaa ttcaagtaga
     3601 taagtctttc attgcctcag gtaatcaagg aaatatga
//
LOCUS       DAIGSZ010000138         3287 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.144, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000138 DAIGSZ010000000
VERSION     DAIGSZ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.144"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            514..831
                     /locus_tag="NOB31_002851"
     CDS             514..831
                     /locus_tag="NOB31_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCI0975010.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(922..1287)
                     /locus_tag="NOB31_002852"
     CDS             complement(922..1287)
                     /locus_tag="NOB31_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975011.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1495..1977
                     /locus_tag="NOB31_002853"
     CDS             1495..1977
                     /locus_tag="NOB31_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975012.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2174..3064
                     /locus_tag="NOB31_002854"
     CDS             2174..3064
                     /locus_tag="NOB31_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HCI0975013.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1140 a          503 c          607 g         1037 t
ORIGIN      
        1 aagcatgctg tgagataata ataaagaaga gtttaaagcg caccccaaac cacttcccca
       61 taagtgtatt acgctttaaa ctcttttata tttgaattca ctaagaagca taccatatat
      121 ttgaatttac taagaagcat accatatttt tgaaaaaaag tgagaaaaaa ggcttataat
      181 taggatttag agtaattaat tagatgttta ttttatagga ctgatactat agattacaaa
      241 tagtatcgta tttcgcaatc ttaaaattat cttcttactg tgaataagat aataaaattt
      301 gtatttgtcc tttttaggta acttatttta atctatatac ctttctggat caacgaaagt
      361 ttatatagtc ataacgccga tggtaactat gcactgtaac gataatgctg ctaaaatatc
      421 tttttacgaa aaacatcaca aggaaaaact taactatggt attatctaaa cataattttt
      481 tcggtattta atatttaatt aggaggtaat attttgcttt tttatagtaa ttttatctta
      541 atagtagcga tattattact tctgaatata tggatttttg ataggagtag aaattcaagt
      601 ataggtttta gaactaaacg aagtttgtct tctaaaaaaa attgggtata ctcacaaact
      661 attttttatg gaggaattgt tttaattagt ttactttctt caacacttta ttctttgaat
      721 attatagatg tttccacctc aaattcaata tctattattg gaatcattat tgctgcaatt
      781 attacacaac tgtttttagt gtttggagag aagaaaagaa gtaaaaaata gaaaaactag
      841 tgatagtttt ggtgatataa gaaaaacata tatgtataaa aagaagaaag tagcttctct
      901 ttgtacatat atggtttgtt tttatggatg ccgagctttt ttataagata aggctaccgc
      961 ccataacgac ccaaggattt gtggaactaa gtaaatacct gcaagaagca agatcagctg
     1021 ggtcggtttt aaaggatgat agaagtaacg ccattcagta aaattggcgc aaaataaata
     1081 ggaagtgaca gtagatataa tattggcaat gaataaagat ataatacgcc tgttcctttg
     1141 aaaataatat ccagcaaaaa gagataaaaa tatcaatgtg atgaacccgc ttacggaatg
     1201 ataacgaaaa tcaagcagta aggcgaaatg cacataagga acaaaagata aaagcaacgg
     1261 aaggtttttc cagcaagttt ttatcatctt tcatcaccac ctaacaagtg ttattatttt
     1321 gttagtttta ttgtaaattg aatcctgcaa taatcaatta ctttttcatt atttctagat
     1381 taaatgaata aactctcatg ccattatctc taaaaaaaaa gtttttcccc ctaatttttt
     1441 tagatagaaa attgtatagt atgatgagag aaaaagtagt ttgggggaac gttaatgaga
     1501 agaaaagcag taatcgatcg gctttattta tttttttggt tttttcctat cgttttgcta
     1561 ccttttacat gggtaaatgc tgttgtacaa ggtgcggaga tattaggcct gatccaagga
     1621 agcggatttg tggtttctag gaattttcca gctttgattg ttttctattt agtgataagt
     1681 gtaggtctct tattaccaaa atctctgatc aatcactaca attggcagct gctttacttt
     1741 tcttgcttat tagtatttac atctatgttt tctttgctgc ctcgcttgat tatcggccct
     1801 aatggtttga gcgagagtgg attgaaggat ttagcttatt cctccatgta tttcttgacg
     1861 atcaaaccat ggttctattt agtaattgcc tcatttattc ttgcaacatt tttttacttc
     1921 tggacagaaa tcaggataaa aagtgaacga tctgtatcta taaaaaataa ctattgatgg
     1981 tggatcatca gtaaaaaaac atatgagctg cgtaaaatgc atgtttctca tatgcttttt
     2041 ttattattat gtaaagaatg cgaaaaacgt ttacatgatt tttacataac ttaactatat
     2101 ttttacagca accatacgag ggatttacag tcgactgata aactttagtt gtaaataaga
     2161 aaggagcaat aaaatgaaaa aagtattgtt tactctaggt atgatgggaa ttcttttagc
     2221 cggatgcggc tcaggatcag gaaatacaga tggctctgcc acacaaaata attcaagtga
     2281 ctcaaatgaa caagtaaaaa tcgttgcggt aggttcgaca gcattacagc cgttagtcga
     2341 tgcagcacaa gaaagctttg tacaagaaaa tccaaattat caaatctctg tacaaggagg
     2401 aggaagcgga actggtttga gccaagtcga agctggagca gttactatcg gaaactctga
     2461 tgtatttgca gaagaaagag acggagttga tgcttcaaaa ttagtggatc ataaagtagc
     2521 agtggtcggg atggcaccaa tcgtcaataa agatacagat gtcaaagata tcaccaaaca
     2581 ggaattgatt gatatcttta caggaaaaat cactaactgg aaggaagttg gcgggaaaga
     2641 tcaaaaaatc aacgtcgtga accgtgcaaa cggcagcggt acccgcgcga cattcgaaaa
     2701 atggggactg gatggtgcta cccctgtgca gtcccaagaa caagattcat caggaacagt
     2761 tcggcagctg gtaagtcaaa caccaggagc aatcagctat ttagctttct catatctcga
     2821 tgattccaca caagcactaa gtatcgacgg tgtagaacca aaagaagaga atgtagcaga
     2881 taacagctgg ggaatctggt catatgaaca tatgtacacg aacggaaaac cttcccctga
     2941 agtccaaaaa ttcttagact acatgatgac agaagaaatc caagaaggac ctgtcaaaga
     3001 attgggctat ttaccaatca caatgatgga agtagaacgt gatcacgaag gaaatatcaa
     3061 ataactagca gataaacatg ccacggtagt cgttactatt aaggaaaaat caactatgtt
     3121 tccccacata tacatttttc ctttaattgt gaaaaatagt tcctcatatt ttgccgtttt
     3181 ttgagctaat accgagggtc agctgattga acaccgttta ttcgaaaaaa agagctacga
     3241 catagaactg tcgtaacttt ttttggctct tcgtcaaatc gtgttgg
//
LOCUS       DAIGSZ010000139         3170 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.145, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000139 DAIGSZ010000000
VERSION     DAIGSZ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3170
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.145"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            132..506
                     /locus_tag="NOB31_002855"
     CDS             132..506
                     /locus_tag="NOB31_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCI0975014.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="NOB31_002856"
     CDS             complement(620..1249)
                     /locus_tag="NOB31_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCI0975015.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="NOB31_002857"
     tRNA            complement(1383..1455)
                     /locus_tag="NOB31_002857"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
     gene            1669..1742
                     /locus_tag="NOB31_002858"
     tRNA            1669..1742
                     /locus_tag="NOB31_002858"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1703..1705,aa:Asn,seq:gtt)
     gene            complement(1840..3141)
                     /locus_tag="NOB31_002859"
     CDS             complement(1840..3141)
                     /locus_tag="NOB31_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0975016.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         1022 a          515 c          594 g         1039 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga taacgaatat taatgtattt
     1501 gtcaacagaa ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa
     1561 ataaaaataa caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa
     1621 agtattgcgt tatttagaag aaattgatat tatattcatg tacttgattc cggcatagct
     1681 cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc ctactgccgg
     1741 agtaaataaa gcttatgcaa agaaaaagaa atcggctctt tgtcaaatag gactgataga
     1801 gtgagataag aacatctaag gtagaattcc ttttctactt tagatgtttt ttgattcata
     1861 ggtaatcaga ttatttagta agaaaattct ggtcttcatt ttccgaaagc ttcgaaagcc
     1921 ataagcgact cgtttcaatg ctttgatgtg ggtatgcaga ttttctattt tggcatttga
     1981 ataaggcaat tcgagggcta aacgaatgcc ggattcatag tttataaaag ctttttttat
     2041 agaatgcagt tcttttggaa cggaattggg catcgttctt acaagtttaa agaaagtgtc
     2101 cgcctctttg tcgtgaaacg cttgaagaat ttcttgatag taaaaatagg cgattcgtaa
     2161 ttcgtcagag atcgaaagca gacgatccac cacttcactt tcggtgagat acgcccaacc
     2221 aaaattgcgc catttggtcc atttgtcata aacaagcttg tcctgtcgtt tgatcagaag
     2281 ccgagacaac gcctttaatt gtcgataata tttggcttgt gttggatcgt ttcgatcaaa
     2341 gcttttcatg attcgtacgc gaatatcctc aaatttacga atgagatgtt tgacaatgtg
     2401 aaaacgatcc acaacgagtt ttgcctttgg aaaacattcc tttatcagag aggcataaga
     2461 aacattcatg tccgtcacga tgacctttac cttcaatcgt gcgcgtcgtt caaattgcat
     2521 aaaataagaa acgagagcct ttttcttccg tgaaggaaga atatccagta attttccagt
     2581 atcgccatcc atacaagaaa aggagtaggg accgacttga tttttcagtg aacgaaattc
     2641 atccattaat aaacaacgcg gtaaccaatt tctttttact tttgtcatgg ggatcagaga
     2701 agcgagtgtc cgagaaacgg tcgaccaaga aacgccgcaa tgcttagcaa ttgtcgtcat
     2761 tgcttgtttt tcagttagct cttctaaaat tttatagcgc acttgtttag cgataaagca
     2821 gtttctatcg acaatgtagg tattcgccgt aaaataggtg tggcagccac gacagtggta
     2881 gcgttgtttc gctaaagcaa gataagtcag ttggttcgca catttattaa gttgaatgag
     2941 cgattttttc tttccgttct taacgatcat gccttcatga ttcatctgtt tacacaaagg
     3001 acagcgacga atttctttac ttaacgtcgc agaaacaaca agactcttga tattcttaat
     3061 gctcttcgat tccacatttg tgatgaaaat gtttttatct ttgattccaa gtagtagttt
     3121 gatatgatga agatcaggca tacagaacgc tcctttgatt gtgttgtggt
//
LOCUS       DAIGSZ010000140         3064 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.146, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000140 DAIGSZ010000000
VERSION     DAIGSZ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.146"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            581..1540
                     /locus_tag="NOB31_002860"
     CDS             581..1540
                     /locus_tag="NOB31_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0975017.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(1527..2132)
                     /locus_tag="NOB31_002861"
     CDS             complement(1527..2132)
                     /locus_tag="NOB31_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975018.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
     gene            complement(2372..>3064)
                     /locus_tag="NOB31_002862"
     CDS             complement(2372..>3064)
                     /locus_tag="NOB31_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0975019.1"
                     /translation="ATISRHSSGKYYISLLCKEEVRELPKSNSAVGIDLGIIDFAILS
                     TGQKFDNNKFTSKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEK
                     VMNQRTDFLNKLSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYK
                     ADWYGRKIIKVDKWFPSSQICSNCGHKDGKKSLEIRKWTCPICHTHHDRDINASINIL
                     TEGLRLHSMGLA"
BASE COUNT          998 a          509 c          478 g         1079 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttattttt
      481 ttaccttcgc cgattgtaaa attaagctag acaactaaaa aagtcatttg tgctacactc
      541 aaaatagttc cgtcgaaaga attataagga gtgagtacaa atgacctata cccatcttac
      601 accaactgaa ctcgtaatga tagaagctta tttcaatcaa tcacactctg tttcaaaagt
      661 agcccatctg gtacaacgtt ctcgacaaac catttataat gtctatcgtt ttcttaaatc
      721 tggtggaagc gcaataagct actatgaaca atataagaaa aacaaacgta actgcggaag
      781 acgtccgatt gtgttaccag atgggcaaca agaatacatt caaaaaaagg tggctcaagg
      841 gtggactcca gatgtcctta ttggtcgagc agagtttcct attgcttgtt cggtacgtac
      901 actatatcgg atgtttaaag ataaaacctt tgaccctcac gatttaccaa tgaaagggaa
      961 aagaaaacca aacggacata aagaaaaaag aggaaaacaa gcttttcgcc gttcgattca
     1021 ggatagaaca actgattata tacagttcaa tcatgagttt ggtcacctag aaggtgacac
     1081 cattgtcggt ggaaaacata aaagtgcggt gatcacgtta gttgagcgat tatctaaagt
     1141 gatcatcacc ttgaaacccg ctggtaggca agctatagat attgagaata gactgaatca
     1201 atggtttcaa tctgtaccga aacacttgtt taaatccatc acatttgatt gtggaaaaga
     1261 gttctcgaat tggaaaaaga ttagtaatac caatgatatt tcgatttatt tcgctgatcc
     1321 aggaacacct tctcaacgag gactaaatga acattcgaat ggcttattac gtaaagatgg
     1381 cttatataaa gctatggatt ttaataaggt atccgaaacc tttatccaat cggtggcatc
     1441 aaaacgaaat catattccta gaaaatcatt acactatcgc acaccattgg aagtattttt
     1501 gagttacgta ggtaaagatg atttgtctag cttaatttga caaacgaaac tttgtaaaaa
     1561 tattcgattg aatattctat ttggcacgac tcacttggca gtatatgtat gtcaatattt
     1621 ttcatctgtt tcataggtat ttcaaaatct aaactattaa aaacatataa ttccctgtaa
     1681 ttatttacat ctaactctac taaatttatc tttggaacaa tagatcctcc acccattcca
     1741 ccataataaa aaaaatcttg ttctctatca aaatagcaca tattaagctc agtttgttta
     1801 tcatcctcaa taattttata aatcaaacct atataatcat gaatgctggc aaaaattttt
     1861 tttaagtcaa gttctaaatc ttcttcgaaa acacatttaa tttctcctac tgataattga
     1921 tactctatat tacatgactt aattagtttt ttagatcccc cctccagata ggcatatgtt
     1981 tcaataatta tgttcttttt attgcttggc aaatttccgt tatttattgc ataaattaaa
     2041 aatgactgtc tatttagccc ataatctaat acaacttctt catactcata tttctttaaa
     2101 tatttaatat gaaaatatgc tgaattaatc aaaactcgag tgttactgtt gttatttatt
     2161 gttgttctat tgtgtataaa attgtatagg ttgtcatatt ttcttggttt agtgaactac
     2221 tcaccactta gctaaaccta acggtttctt acgtttgaag tgggagcttc ttgggaagag
     2281 agcatacttg atagcgtatt actttactaa cagaggtgcc tcttatttac caagctatcc
     2341 ccgtagttcc tacggttctt gtttatttga tctaagccaa tcccatagag tgtagcctta
     2401 gaccttcggt caggatattg atactagcgt tgatatctcg gtcatgatga gtatgacaaa
     2461 tagggcaagt ccattttcga atttcgagag atttcttgcc gtctttatgt ccacaattcg
     2521 aacagatttg gctagatgga aaccacttat ctactttgat gattttccga ccgtaccagt
     2581 cagccttgta ttgtaattta gacacaaaac tagaccaaga aacatccgaa atactttttg
     2641 ctagtttatg attacgcaac atgccttttg tgtttaagtc ttcaatacag atgatatcgt
     2701 gatttttgat aatttctgta ctcaacttat tcagaaaatc agtacgttga ttcattactt
     2761 tttcatgcaa tcgtgctact ttacgttttt gtgtttgata atttctagct tcaaacagat
     2821 tgataccttt ttgtttagct aataaggcac gtcttgacaa cttacgttgt tcacgtttga
     2881 gtttcttttc cattttggac gtaaatttat tattatcaaa tttttgaccg gtagaaagaa
     2941 ttgcaaagtc tataatacct aggtcaatac caacagcaga attagattta ggtagttcgc
     3001 gaacttcttc tttgcataac aaagaaatat aatatttacc gctagaatga cgtgatattg
     3061 tagc
//
LOCUS       DAIGSZ010000141         3031 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.147, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000141 DAIGSZ010000000
VERSION     DAIGSZ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.147"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..482
                     /locus_tag="NOB31_002863"
     CDS             <1..482
                     /locus_tag="NOB31_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCI0975020.1"
                     /translation="LTYRTEDEDSIRYFVLFTGFEINKTKKFVEVSVNPDLEYIINGL
                     TAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYYVVRIEEFRSLMDIPEYYQMGNI
                     DQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLEFTFSSLTSDLPKISLRNWLEE"
     gene            complement(619..1035)
                     /locus_tag="NOB31_002864"
     CDS             complement(619..1035)
                     /locus_tag="NOB31_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975021.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1038..1322)
                     /locus_tag="NOB31_002865"
     CDS             complement(1038..1322)
                     /locus_tag="NOB31_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975022.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            complement(2022..2117)
                     /locus_tag="NOB31_002866"
     CDS             complement(2022..2117)
                     /locus_tag="NOB31_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HCI0975023.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            2792..>3031
                     /locus_tag="NOB31_002867"
     CDS             2792..>3031
                     /locus_tag="NOB31_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HCI0975024.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLN"
BASE COUNT          965 a          482 c          567 g         1017 t
ORIGIN      
        1 atcttactta ccgtactgaa gatgaggatt ctattcgcta ctttgttttg tttactggtt
       61 ttgaaatcaa taaaacaaaa aagtttgttg aagtcagtgt taatccggac ctagaatata
      121 ttattaatgg tttaacagct gaatttagta gatttgaatt atctgctttc acgtcgttgc
      181 gttctacgta tgcaaaaact ctattccgac tgcttatgca gtaccgttct actggttatt
      241 atgtagttcg tattgaagag tttaggagct taatggatat cccagaatac tatcaaatgg
      301 gtaacattga tcaaaaagta ttaaatcctg cattacgaga actaaaaaaa tacttcaatg
      361 atcttaaagt cacaaaaata aaagcaaaaa agggcaataa aatcgccaaa ttagaattta
      421 ctttttcaag cctaacgtca gatttgccaa agatttctct gcgtaactgg ttagaagaat
      481 aaataaaaaa gaactcgccc cccttacatt aagcaagtag acaagtccct tacaaccgac
      541 taagattgct agtacattct agcatattgt atggggcttc taaataaaaa acagatagga
      601 ataactccta tctgtttttt atcgttttag aaaatttgtt gggtcgaaat ttctagaagt
      661 gactgtttga ctggtttctt tttgatgatt ctttggtcga tttcgatttg atggatttag
      721 tttagcttcg attttttctt tcacttcttg atatacttta gaatttgtgc caataagaac
      781 gcctgtatct tttagatata aatcagcaaa ttctgcgatg atttcagtca tgatggaaat
      841 ttcttttccc atagcattta gttttgcctg attgctggta gtggtcgtgt tggtatcggg
      901 ttcataactc atacataaaa agcgaatggc ttccgagtag ttattgatat ctggattttt
      961 ttcgatgatg gaatctaaaa cgtcaacatg actagggtac aaagtaacat gtttttggac
     1021 agaagttttt ctcatggtta tatcattcct ccgataagca tttcaatgat ttgattattt
     1081 gtgtagacat actcgcttaa tatttgagta ttttctgttt ggatagcaat aaatttatcg
     1141 agcaataaat cgaattggtc ttttttgtaa gtcgtaagtt gacggtcaaa atcactttcg
     1201 attaaaactt ttagatattt atttcgactc catttttctc ctgttttatt cgtgagttct
     1261 tggcaacgtt tgtctattgt tgcaacaaac tttggatcaa tattccgaac taaaatgtcc
     1321 ataaaaaatc tccttttgca attatgtata atttatgtat accatacaaa tactatattt
     1381 gtatagctgt tttttgccaa aatgctatac ataagctacc cacgatggcg aaaaagtgat
     1441 atcaaatttt tttctgagaa acgtgatagg cacagcctat ctacccactt tttttagaaa
     1501 gtgggtacac gtttccttat gctctttaaa attcgggggg gagtgctgca cgtgtaatcg
     1561 ataaccaaat ttaacagacg aaaaattgtt ggaatataaa aatatgacac ccgaaagaaa
     1621 acgatcgttg gaaaaattaa tgcaactagt gaacgaagac ggcggaattt cagacgcagc
     1681 ttttgacgca tggagcgaat ttcatggaga atataattaa gtgggtttaa atggctctaa
     1741 aatcgcttct aagagttttt tagcttggac caatgaaata caccaaaaac taaataaaac
     1801 gtcttaaatc gaaaaatacg agctctcaga gcgactttat ttgtaaatgt tgcatataag
     1861 aaataattac ggattttaga cttttgtagg atatttttga aataaatatt tatttctgtt
     1921 ataatttgat tgcaaataag tgaacacgaa acacacgaaa tccccagaga ggtcggattc
     1981 tctggggctt tttttgtggg ctgagtcgcc ttaattaagt tttacttctt gtttcggtta
     2041 ttcaaccagt aactgaacaa agcgcttaaa agcccaacaa gaagggagca aataaagtta
     2101 gtgaacacga aacacacctc cttccagtcg caagactgtc ggataggcga caatcaatta
     2161 tacaataaaa aagcaaaaat aagcctaagt tttttattgc cttggggttg ttagggcttg
     2221 ccctgaccgc ctgtaaggcg ctttagaacg aaggacatag tttttatcga atcttgtctt
     2281 agaacggctt agacgagctc tcaggacgcc acaaaggagt ccctaatgaa ttatttttgg
     2341 cgaaggagcc taaaggcgac tgctgcaagt aaaatgtgag agcgtagcga tcactccttc
     2401 ttacagcgac catagggagc tagattggca gtttaatatc atgcgcgaac ctgtttattt
     2461 taaaaagtgg gtgatttttt ggcgggaaat tttgctcgcg cgcgcgcgtt tattttattt
     2521 attttttaaa gattttttag aacccttttt agggggcagt tgagccttac tctcccaacg
     2581 gatacagaag ggtactaaca actttttatc tgagtactaa caacttttta tctgagtact
     2641 aacaactttt tatctgagta ctaacaactt tttatctgag tactaacaac tttttatctg
     2701 agtactaata tccttttgta taataacaac caacctattt acgagttggt tgttaaaggt
     2761 tattatttat ttgtaagggg ggaagaaagg aatggatgaa aaaacggaat taacagtcaa
     2821 atatcaaaat gaattgaatt tagtaccgct gaaaaatttc aatgctaagc agatggattt
     2881 attttttgca ttatgcgctc gtatgaaaga tcgtggtttg aaaaaagtta gattttcttt
     2941 cgaggaatta aaagagttaa gtgattataa gatgactgct acaaaagcct ttgtcggtga
     3001 tttagaaaag ctctataaag atatgcttaa t
//
LOCUS       DAIGSZ010000142         2995 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.148, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000142 DAIGSZ010000000
VERSION     DAIGSZ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2995
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.148"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            380..1015
                     /locus_tag="NOB31_002868"
     CDS             380..1015
                     /locus_tag="NOB31_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0975025.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            1357..1992
                     /locus_tag="NOB31_002869"
     CDS             1357..1992
                     /locus_tag="NOB31_002869"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCI0975026.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            2099..>2995
                     /locus_tag="NOB31_002870"
     CDS             2099..>2995
                     /locus_tag="NOB31_002870"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0975027.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSV"
BASE COUNT         1018 a          451 c          558 g          968 t
ORIGIN      
        1 tttgtgaaat agtgcccccc tgttagataa cgggggcaca gacaaggctc gcaggctcgc
       61 cagccgacaa agcatttctt ccccttgaca caaggtgtca tggcggtaag cctgagaggc
      121 ttccgccacc gtgtcagaaa tactttgtca gcaagttctg ttttgccttt tctaacaagt
      181 tccatttcaa ccgatattca tatctacgga tttaatcaga taggtatttc tttttgaatg
      241 tttttatatt tcattctatt gtgcttattc gattacaaga acatagtaat tcttatatgc
      301 ttatttgtca atatcttttt ttgcctttac aaatcatatt aagcatgata gacttataat
      361 agcgaagata taacgagata tggagggtta tgcaatgaaa ataagccatt taggaaataa
      421 tatacagacc ataagaaaat ttaggggaat gaaacaacag gaacttgcgg acaaaatcgg
      481 tatcaatatg cagagccttt ccaagattga aagagggttg aactatcctg cctatgaaac
      541 gctggaaaag ataatggaag tgctggacgt tacgcccaat gaattgttgt cgggagaatg
      601 gaagtatgtc aatcaatctg aaaaggaagt ctgtcagttt ttaagagccg aagaacgtct
      661 aaatgcagaa ctgaaacatg gacactatga taacttcttt gacagcgagg aagaatggct
      721 ggaatatgag ttagaaaagt tacgggaata tattacagac tatatcaacg ggaaaagcat
      781 tgaagcgtcc gacctttacc caatcaaaga atttatccag catttgaagt ttcaaaaatt
      841 attagaccgc tatgatgatt tatacagtat ggatatgttt ggggaaagca tagagggaca
      901 taagtataag acaccttatc aagtcgtgaa aatgataaac ccgaactcaa aagaagatat
      961 ggaactgtta cgagaagtat taaggaataa caattttgat gatgaggacg agtaactttt
     1021 ttcctcttgc gagaagatac agcaaacaaa aagcccgatc aagagtgcaa agcaccacca
     1081 atggtggcaa agctcttgac agggcttttt cttttctgtt gtgggcaatc aagaggaaga
     1141 aagggataaa atctgatttg tggtaaatca ggcaaaggca acgcaggtat cacagtatga
     1201 attgacaccg cataaggaaa gcaactggaa gattgtagaa taaatgaaaa aggcttgcat
     1261 tctgcatttt tataaaattg caagtcttta tattgacaag cataaaatac taagatatac
     1321 tttaatcaga ccaacggttt gtattggagg taagttatgg cacgaaataa atatccagaa
     1381 gaaacagtaa aactcatttt agatgtttct acaaaaatgt tttgtgaaaa aggatatgat
     1441 aacacatcat tgcaagatat tatcaatgaa acaaaacttt ctaaaggtgc tatttatcat
     1501 catttcgatt caaaggaaga tattttaaaa gcaatttttc aaagaattgg aaatgaaaat
     1561 gcagtaatat ttgctaaaat tagagataac gatagtttaa acggtttaga aaagttaaga
     1621 gaaatattta agacagcggt attcaattct aaccaaagcg ttttattgac agtttctcct
     1681 caactattaa acaatcctcg ttttcttgct atgcaaatag aacaaatgta tgaaattgta
     1741 gtacctgaat ttgttgaacc cgttttagaa caaggtatca aggataagtc tttggagatt
     1801 gaaaattcac atgaaattgc agaagttatc atggtattaa gtaatgtatg gctcaaccca
     1861 ttagttgaaa tgacggataa agagggtatg gaaaaacgtt gcaatacatt caatgccctt
     1921 ttaaatggaa taggcataga cacattatta gacgaagaaa caatttctgc atttatacag
     1981 ttttgtaaat aactgtattt gttatcccta tacgatagac tgctctataa aagagcagtt
     2041 tatttaaacc attatataaa ccgacggtct gtttgattaa ataaaaagga gagattttat
     2101 gcaagcagaa aaaaaacttt ttaatcgtga ttttatactt gttgttatag gacagataat
     2161 ttctttattt ggaaacgcta tcctacgatt tgcattaccg tactatttgt taaaagaaac
     2221 tggttcatca gctttgtttg gtattgctac agcctgctct tttttaccta tggttatttt
     2281 gtcgctggta ggtggtatta ttgctgacag gacaaataaa agaaacatta tggtcatact
     2341 agattttgta acagcaatca taattttagt attttatttg tcattgggaa aaattcctat
     2401 catacctttg tttattgttg ctttgatgtt actttatggt atttctggtg catatcaacc
     2461 agcggtacaa gcaagtattc ctctattggt atcatcagat aaacttaccg tcggtaatgc
     2521 tataataaat caagtaaata ctttagcaaa ctttatcgga ccagctataa gcggagtagt
     2581 ttttcaattt tatggtatca atcccatttt aattgttagt attatatgtt ttactttttc
     2641 agccattatg gaaattttta tccatattcc acaccaaaaa agacctcgtg aagtaggtgt
     2701 aattgcagtt gctaaaaacg atttaaaaga tagttatacc tttttgaaaa aggagaaacc
     2761 catttttata tccgtaatct ttttggtttg cattttcaat ttggttttaa gtgctgtttt
     2821 aattgttggt ctgcctatct taatttctga agttttaaaa atgccagata cactatatgg
     2881 tttttcacaa tcagcattat cattaggtgg tttatgtggt ggtattttaa cagctcttgt
     2941 tgcttcaaag ttaaaactaa aaaaccttta taccttgtta cttatttgtt ctgtt
//
LOCUS       DAIGSZ010000143         2947 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.149, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000143 DAIGSZ010000000
VERSION     DAIGSZ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.149"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(449..865)
                     /locus_tag="NOB31_002871"
     CDS             complement(449..865)
                     /locus_tag="NOB31_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975028.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIERNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGILIGTNSKVYQETKEKI
                     EKQLNPSKRNQPKNRQKETNQTFTSKNFDPTNFLKR"
     gene            complement(867..1148)
                     /locus_tag="NOB31_002872"
     CDS             complement(867..1148)
                     /locus_tag="NOB31_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975029.1"
                     /translation="MDILVRKIDSKVIAKIDKRCQELTNKTGKKWSRNRYLKVLIEND
                     FDHALMHYKKDQFDLLLEKFIAIQEKNTETLNEYVRTNNQLIETLIGGR"
     gene            1948..2922
                     /locus_tag="NOB31_002873"
     CDS             1948..2922
                     /locus_tag="NOB31_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCI0975030.1"
                     /translation="MSKRGTIINEWEKLNRISNRRLNAQTMCTPLKMQWSIDRITIVG
                     TLRENIYYHTPHDVLILDFEQLMRLNEGNGYLKAVGNNGWQLLDQHEENIAYIEILKF
                     QEGKGRIDFNPNKISQFLAGSMKNFIHDLFLEPHFSRADIACDIIDVPDDFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKVVPKEIDTWWRLELQ
                     LRRGKATDWHAMVHESLDSFASPHYLPEDVKVTDRMMITALITEHSYWGQIHRNSKYK
                     YRELLKQESQNDELTNHLRETFSESADDLKRELDTWLQGLDVTEVGAE"
BASE COUNT          913 a          438 c          603 g          993 t
ORIGIN      
        1 aaaaaaactt gctgatgaat tgggtgtatc gaaaaatacg gtgcgcaatc aactggtcaa
       61 ttcgggattt gaccttgctc agtataaaga aaaaaatgca gtggtcaatt gaccgaaatt
      121 tatgtctttg ggttttgggg ttttaaaacg aaaaaaaggg ggcgattttc gccccctttg
      181 ctctatgtga aaaatttgtt atacttattt tatccttaaa acataccaat ctttttctta
      241 tttagctgct cgtacgagca gcttttttta cgattatgaa ttcaaatcat gtatttataa
      301 tttttttgtt tttatctttt tttctgttat ttcttctgaa attcgttttt ttcattcaat
      361 tggttactat cttattgtaa atgttgctat taagatggtg atcctaccca aaaaataaac
      421 caggaattta aatctcctgg tttatttttt atctttttag aaaatttgtt gggtcgaaat
      481 ttttagaagt aaatgtttga ttggtttctt tttgacgatt ttttggttga tttcgtttgg
      541 agggattaag ttgtttttca attttttctt tcgtttcttg atacacttta gaatttgtgc
      601 caataagaat acctgtatct tttagatata aatcagcaaa ttctgcaatg atttcggaca
      661 tgatggaaat ttcttttccc atagcattta gtttggcttg gttgctggta gtcgtagtat
      721 tggtatcagg ttcataactc atacataaaa aacgaatggc ttccgagtaa ttgttgatat
      781 ctggatttct ttcgataatg gaatctaaaa cgtccacgtg actgggataa agggtaacgt
      841 gtttttgaac agaagttttt ctcatgttat cttcctccga taagtgtttc aatgagttgg
      901 ttgtttgtac gaacatattc attcagcgtt tcagtatttt tttcttgaat agcgataaat
      961 ttttcgagta ataaatcgaa ttgatctttc ttgtaatgca taagtgcgtg gtcaaaatcg
     1021 ttttcgatta ggacttttaa gtagcgattt cgactccatt ttttgccagt tttatttgtg
     1081 agttcttggc aacgtttgtc tatttttgca ataacctttg aatcgatctt ccgaactaaa
     1141 atgtccatag aaaaactcct ttcgcatttg tgtataattt atgtatatca tacgaatata
     1201 gtatttgtat agctgttttt tgctaaaata ctatacataa gctagccacg atggcgaaaa
     1261 agtgatatca aatttttttc tgagaaacgt gataggcaca gcctatctac ccactttttt
     1321 tagaaagtgg gtacacgttt ccttatgctc tttataaaat ggtgatgtgc gacttttttc
     1381 tgttcgtaaa aataaaaaaa gtttacgaaa atgaaactaa actgaacgat tatgacgggc
     1441 atgtaatcaa gatgaaatga ttttataagc gcgtattttg cgttctaaga cgttttagcg
     1501 ttcatttcgt ttagttatcg gcacaatcgt taaaacacgt aagagaagcg agaatggagc
     1561 ctgtaaggcg actggtagcg aaacggcgtg ttagattgtg caagccgaga actgaatgaa
     1621 atgaagagcg gaagcgtgaa ataatttcgg caggaggagg ctcaaggggt tcggggaatg
     1681 aaattccctg aggtcttttt atttttttaa gaggagtgct ataatcaaag aaaacgagaa
     1741 aaaagagcaa aataaaagcc gaacggtgtt ggaagcaccc ttcggctaat tacggaaact
     1801 actcacctag ttccgtaact caaattcatt atacgaatat ttttaggttt cttcaagcta
     1861 gagatttttg gatatggatt tttagagtta cgtgaactct ggaaattctt tccaaaaatc
     1921 tcttttttct ttgaggagga acaaaatttg agtaaacgtg gcacgatcat aaatgagtgg
     1981 gaaaaactta accgcatatc taacaggcgg ttaaatgcac aaactatgtg caccccctta
     2041 aaaatgcaat ggtcaattga ccgaattacc attgttggta cattaaggga aaatatttat
     2101 tatcacactc cccatgatgt gttgatttta gattttgaac agcttatgcg tctaaacgaa
     2161 ggtaacggat atttaaaagc ggttggaaat aatggctggc aattactaga ccaacatgag
     2221 gaaaatatag cttatattga gattcttaag tttcaagagg gaaaagggcg gattgacttt
     2281 aaccccaata aaattagcca atttctggcg ggctcgatga agaactttat ccatgattta
     2341 tttttagaac cacatttctc acgtgcagat attgcttgtg acattattga cgtgccagat
     2401 gatttcatta cccaatatcg ggtggttgat cctgtttctt tcaaaccaat ttacggtcgg
     2461 tctgggaaac tggaaacagc atattgggga agtcgtgcta gtgaacgaca gattcggatg
     2521 tataacaaaa aattggaaca agaaagaaaa cggaaagttg ttccgaaaga aatcgatact
     2581 tggtggcgac tagaattgca attgcgaagg gggaaagcaa ctgattggca tgcaatggtt
     2641 catgaaagtt tagatagctt tgcaagtcct cactatttgc cagaagatgt gaaagtaact
     2701 gacagaatga tgattactgc tcttataacg gaacatagtt actgggggca aattcataga
     2761 aattcaaaat ataaatatcg tgaattgtta aagcaagaaa gtcaaaatga tgagttgacg
     2821 aatcatttgc gagaaacatt ttcggagtcg gcagatgatt tgaaacgaga attagataca
     2881 tggcttcaag gacttgatgt gacggaagta ggtgctgaat gagtgattcg atagaaaaaa
     2941 tgaccct
//
LOCUS       DAIGSZ010000144         2714 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.150, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000144 DAIGSZ010000000
VERSION     DAIGSZ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2714
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.150"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            144..1151
                     /locus_tag="NOB31_002874"
     CDS             144..1151
                     /locus_tag="NOB31_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCI0975031.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1163..2167
                     /gene="neuB"
                     /locus_tag="NOB31_002875"
     CDS             1163..2167
                     /gene="neuB"
                     /locus_tag="NOB31_002875"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HCI0975032.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2164..>2714
                     /gene="neuC"
                     /locus_tag="NOB31_002876"
     CDS             2164..>2714
                     /gene="neuC"
                     /locus_tag="NOB31_002876"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HCI0975033.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNR"
BASE COUNT          989 a          344 c          532 g          849 t
ORIGIN      
        1 tttctttgat acttcatatt ttaatcaatc aaatgttgat tcgttacgtt ttgacatcat
       61 tattgataat tagtttagtt atatattttt taaagattaa gaatcgaatt atagatgact
      121 ataattcata ggaggagata taagtgttta aaggaaaaac aatattagta actggcggaa
      181 ctggttccat tggaagtgaa attgttcgtc agcttttaaa atatgaacca aaagctatca
      241 gaatttatag tagaggtgaa gaaaaacaat tttatatgca acaagagctc tcaaatcaca
      301 ctaatttgag atttttaatt ggtgatatca gagactctca aaggattgat tatgcatgtc
      361 gtgatgtgga tattattttt catgctgccg caatgaaaca cgttccagca agtgaatata
      421 atcctatgga agctgtaaaa acaaatgtga tgggaactca aaatgtaata gatgcagcga
      481 tcaaaaataa tgtaaaacat tttgtaggta tcagtacaga taaagtagtg agtcctacta
      541 acaccatggg tgcgacaaag ttattgagtg aaaaattaat aatagctgcc aatcagtata
      601 aaggaaaaac agaaacaata ttttcttgtg taaggtttgg aaatgtcatg gggtcaagtg
      661 gatctgttat tcctcttttt agtaaacaaa taaaaaacaa taaagatatt actttgacag
      721 atgttgatat gacacgattt atgatgtcaa taccggatgc tgcaagatta gttctgtctg
      781 ctgctatgaa ttcaaaattt ggagaaacat atgtcttaaa aatgccggca atcaatattt
      841 taactttagc tcaatcatta ataaaaatat ataatgatac acatgatgaa aaatatagag
      901 gtgaaataaa agttgtaggt atcaggccag gagaaaaatt atatgaagag ctaatgacta
      961 cagacgaaat tgaacgctca tatgaaaatg ataaaatgta tatcattcca ccacactatc
     1021 atgctactga cgaactgtac aaagattatg aaaaaattaa aatcactgca tactcttcag
     1081 atgcaacaga attaatgagt ggacaggaat ttattagaat cgcaaaagag aataatgtcg
     1141 tgacttggta aggagtttta tgatgaaatc agaagtatat gtaattgcag aaattggtgt
     1201 aaaccataat ggaagtctag atttagcttt agaaagtatt gataaagcta aagaatgtgg
     1261 agctaacgcg gttaaatttc aaacatttaa aacgaataag ctagtttcca aaaaggctcc
     1321 aatggcaaaa tatcagaagg ataatcttaa agaggacagt tctcaatttg aaatgctaaa
     1381 aaaattagaa ttatctcaat ctgattttat tagaataaaa gattattgta tacaaaataa
     1441 aattgatttt ttgtctactc cttttgatga agaaagtgca gactttctaa aacaaattgg
     1501 tgtacaagga tttaaaattg gctcaggaga tttaacaaat ttaccttttc ttagaaaaat
     1561 agatatgtat gggttgccag ttttattatc tacaggtatg gctgatattc atgaggtcag
     1621 tgaggctgta gattgtttca tagatagtcc agttactatt ttacattgta cttcaaatta
     1681 tccggctagt tctgaagata ttaatttatt ggcgattaac acattaaaag aaatgttcgg
     1741 gatacccgtt gggtactccg atcattcatt gggatatgat gttggtattt gtgctgttgc
     1801 gatgggtgct aaggtaattg agaaacattt taccttggat aaggaactac ctggtccaga
     1861 tcataaagct tctttagatc ctcaggaatt tgcagatttt gtaaagcata ttagaaacac
     1921 tgaaatattt ttaggtgatg gtgttaagcg agcaatgcct tctgaactta gtacaaaaga
     1981 agtatcaaga aaaagcctag tggtcactga gaatttaaat gtgggagata ttcttacaga
     2041 gaaatctctt acaataaaac gtcctggaaa tggaatagct cctaagtttt tatatcaata
     2101 tattggcaaa aaagttaaaa gaccaataag tgcagatagt gttctgcttg aggaagatgt
     2161 tgaatgaaaa aaatacttat agtaagtgga acacgagctg attatggaat atataaacct
     2221 gttgctgaga atttactaca agataattgg gatgtatcat ttgttgtttc tggaatgcat
     2281 ttatcccata aatatggatt tactaaagaa ttgatcttag ctgacggatt tagaattagt
     2341 ggagaagttc aaagtttgtt tttagagaac aataagggaa acatggctcg gtctgtggca
     2401 ttagagataa atggtttcac aaatatattt gaacaaacta gccctgattt tgtattatta
     2461 ctaggggata gaggagaaat gttggcagct gcgatagctt gtttgtatct tggaatcaaa
     2521 acagcacata ttcacggagg cgaagtgtct ggtactgtag atgaatcaat aagacatgcc
     2581 ataacgaaaa tagcatctgt tcattttgct gctacggaaa aaagcaaaga gcgtttaata
     2641 aaaatggggg aagattcttg gagagttttt cccgtcggag ctcctagaat agatactatt
     2701 ttaaataata gatt
//
LOCUS       DAIGSZ010000145         2490 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.151, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000145 DAIGSZ010000000
VERSION     DAIGSZ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.151"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(365..1657)
                     /locus_tag="NOB31_002877"
     CDS             complement(365..1657)
                     /locus_tag="NOB31_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCI0975034.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1931..2191)
                     /locus_tag="NOB31_002878"
     CDS             complement(1931..2191)
                     /locus_tag="NOB31_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975035.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          844 a          465 c          381 g          800 t
ORIGIN      
        1 tatgggctac tctgtgatac ttattagcca ttaaactatt ttacccacat agcatatatt
       61 ttgaaatcgt tcattccgta aattcaacta aatatgccta aaaaaataaa aaatctaaga
      121 tagaataaga tttattcagt cttagatgga tttatagcaa ctttttcgta acaactttaa
      181 aaaatacgaa aagaaagagc tgttttactc tgactacgtt gctaaattgt cgtttaatca
      241 ttcatttaaa ccaaatcttt ttttatagaa ttcgttttaa tcctcctgaa tccaaaaact
      301 atgaaaaccg taattaaata gttaagagtt tttaaccacc ataattctct cggctatttt
      361 gaaatcagat aaattttgat cggacacata gttgaataaa cctaccgttg ttacggaagg
      421 taaatcgcat acttttcatt ctagaggaga aggtctcgtt gatcattaac tgattaagca
      481 ccatagccca gttttgaatt cgaccacctg accacttcgc gtgtaattct ttcgtgcgta
      541 aataaagtag ttttaggagt gcattctcat tagagaacgc tccttttttt gtgacttttc
      601 tgaagctgga gtggacactt tcaaccgcat tggtagtgta cataattttt cgaatggcac
      661 taccataatc aaatagttgt tcaacatgtg caaagttccg tttccagaca tctacagcac
      721 cagaataatg agaccaccga ttttgaaaac tgtcaaaagc agcatgtgca gcgtttagag
      781 aagaagcacc gtagaacttt ttcatatctc ggcagacttc cttatagtcc ttacttggaa
      841 tatagcgcaa tgcatttcga acaagatgaa caatacagcg ctgaacaatt accgatggaa
      901 agatcgcttt tgcgccttct tcgaggccag aaacaccgtc catcgaaatg aaaaagacat
      961 cttcgacacc acgtgctttc agttcatcaa atacttgcat ccagcgattt ttagattctg
     1021 tttgatttaa ccataatcct aaaatctcct tatttccttt gagatcatag ccaagaatgg
     1081 tgtatacagc atattctttg gcttcataat tttctcgtaa agtaacatac atacaatcaa
     1141 cgaatagaaa ggcataacac tttgctaggg ggcgggcttg ccattcttcc aattcaggaa
     1201 ggacagcgtc agtgatatct gaaatcattt catgggaaat atcaaagcca taaatagctt
     1261 cgacggttgc ggcaatatct cgttgactca ttcctcgtgc atacatggaa agaaccttcc
     1321 cttcgatgtc ggagacatct cgttttctct taggaattaa ctctggttca aaggaagctt
     1381 cccggtctct aggaacatca atagctactt caccaaaact ggttttaagc gttttagttc
     1441 catagccatt tcgacggtta tcgtgttcct taggctcttt agaatgggca tcataaccta
     1501 aatgattatt caattctcct tgaagcattt tttcaaaaag gggcccaaac acatctttca
     1561 aagcatcttg catgtcatcg acagattcag gttgataggc attcagaatg gattcagcta
     1621 acttttcggc atcaggattt cttttctttc tagccatcgt gtaatcacct cttgatctta
     1681 ttgtagaaaa agaaaaaccg cgaagcaacc acctgcctag gattaatggt tacttacacg
     1741 gtttatatta cactctcatc attaaaaaag tatctttcga tattactaaa caatgaaatt
     1801 atctatttga aatttaaatc tgataatata ttgagtgttc caatgagggc tttgatccta
     1861 ttatccatat ctttttcagt tttaatattg atacacatta taagaaaaag aaacttttgg
     1921 ttaatttatt tcatcccagt gcaaaatata aaaaagtaaa atagaccata ggcaatagat
     1981 taacaattaa tataatacaa gcaaatattc tattcattgt atttctgctt tcaaaaagtt
     2041 ctaatattga aagtataatt ccacaaatgc ctataataag tatgggaata agattagaaa
     2101 ataacacccc gagccaatct gtgaaaatta ctatatttac taatatccct attaacatac
     2161 ctatcatatt tattaaatca atttttttca ttagatattt ctcctttatt aaatctgaag
     2221 tacttatatt aaaataattc taaactattt acctcaaaaa gtgcaataaa ttatttctga
     2281 acaataaaat gatagtcaaa acaaaaaaat attgttaatc gttcagagcc atccgagagt
     2341 gtaaaatatt ttgtgtaaat gaaaaaatcc atacaaaaaa ggaaggcgct tctgtagaat
     2401 aaagttaacg acaaccaatt cacagaaaag aggacttccc tatgaatgat tttactacag
     2461 aaattgtgca aactctagtc actaaaggcg
//
LOCUS       DAIGSZ010000146         2398 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.152, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000146 DAIGSZ010000000
VERSION     DAIGSZ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.152"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            207..2069
                     /locus_tag="NOB31_002879"
     CDS             207..2069
                     /locus_tag="NOB31_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0975036.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="NOB31_002880"
     CDS             2069..>2398
                     /locus_tag="NOB31_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCI0975037.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DAIGSZ010000147         2384 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.153, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000147 DAIGSZ010000000
VERSION     DAIGSZ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.153"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(365..1156)
                     /gene="msrA"
                     /locus_tag="NOB31_002881"
     CDS             complement(365..1156)
                     /gene="msrA"
                     /locus_tag="NOB31_002881"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCI0975038.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
     gene            complement(1347..1982)
                     /locus_tag="NOB31_002882"
     CDS             complement(1347..1982)
                     /locus_tag="NOB31_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HCI0975039.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
BASE COUNT          772 a          488 c          368 g          756 t
ORIGIN      
        1 tagttattgt ttgcgctttt atacggaatt tagttcatca ttaatgtgga attcgattag
       61 gtgtctatta attatcaaga tgattctcta caaaattcca tagaaaaatc aagattctac
      121 aattcgaatt ctctttcaca tggaaataaa ggctagtaaa aaaacaggag ttgtgacaaa
      181 agacttgtca tacctcctgt ttccttgcga cttgaagctg aatgctttgc gccacaacct
      241 tttcctcggt gttctcaaag caactcctcg aaataattca taactgtcca aaaatatgaa
      301 aagctatttt tgtcagttgc tcattatttt gtcggagctg aacgctttgc gccacaacct
      361 tcctctatct atgtcgctga aaaaataaat gaagctgatg cgaatgcttg atctttttat
      421 atcttttagg ttgcttctga taaaattgtt gatgatgatt ttcagctggc caaaaagtct
      481 ttgcttggcg aatctctgta acgataggac ggctaaatcg gttagattga atcagttgtt
      541 ctcttgattt ttcagccaat tgcctttgct tttcattaac aacaaataga attgaacgat
      601 attgtttccc ccgatcttga aattgaccaa aggcatctgt agggtctgaa atttgccaat
      661 aaatctccaa cagctcttca taggttattt gacgtgtatc aaatatgatc tcaacagctt
      721 caacatgccc agtatatcca ccactgactt gatcgtaatt tggttttttg gtctctccac
      781 ctgtataacc agataacact gagattacac ctggttttgt ttcaaaaggc tcaaccatac
      841 accagaaaca gccaccggca aaaatcgccc gttcttggta taagggtgaa gttatcttat
      901 gtttggcata atcataagcc tttgcactcg ctgactcccc tgtgattctt aaataaaaat
      961 ccatcgcatc tggtgtcaaa ttatctcgta gtgctagcgg acgcaagttg acctctagtt
     1021 tttctatcac ctgctttatc gacatttttg ctaggtcttc ttttgcctct tcaaattgtg
     1081 ttctttccca ttctcttgta tttcgattta aaataatatt ataaaggtct atttccatct
     1141 gctccacatc taacatgaag tcaccctctt tcaagttttc ttcttattca ttcaaaaaat
     1201 gactacctga aatttagcac aacgcataac aagttaagac taacttgctt ttcgctctcc
     1261 tcatctctat tcttagtcga acacatccac acgaatggtt acccatagag aaattctttt
     1321 acttaatcag cttcacactg ctttttctac tttcgtagtt gaaaaaaact taaacaaatc
     1381 atcggcaaat agttaaagaa aaaacttaag cgttgaaaga agcccaattg cttaaagaag
     1441 gcaaactgac taatcgacgg aatccgtgct aatccgtaaa gacctgcaat tagtaaacta
     1501 ataactgtta aaacaagata aaaatggcta agcgtacctt gaccactttg acgataaagc
     1561 agaacaagta acaatgggaa aagtagaaag cctgcatagc ctagcccaga acctatatta
     1621 tggatccaag tcgatagatt ccaagagctt tcattcgtat tgatactgaa taacccagta
     1681 aaaatacaat cacctatccc atataaacca actgttgcaa cagcaagtat tgcaagtgtt
     1741 tttgatgttc caataaatag gtgatacaac gcaggcaacg aaagaacaaa aaaaagtcca
     1801 gatacaactg accagaccaa gaaagcacgt ctgactggac tatctacgtc accaaacaca
     1861 ctaattacgg tagtcatttg attcagtttg ggataaaaaa ggccaaggat atacggtgtc
     1921 gataaatcac taatcacacc taataataaa aaataaaaac catatttttg caaaaaaatc
     1981 attttcttct cctacttttt agtgattatt cgatacatcc aacaatcaaa ttttttctca
     2041 ttttaacaca tatttttatt ctagttgcct tttgaacaat caataacata aaggtgagtt
     2101 tcttctacat tttaaaaaat cgaatggcac tgaagagttc agttgtcagc atcaatctcc
     2161 tactcaaaaa ggcaaaaaaa cgtaagtcag atgttgttga catctcactt acgcatccat
     2221 tgattgaaaa tttcttagta aaatcggttc tataatattt tgtgttggtg gaaaatcgaa
     2281 agcgattttc tactaacact tttttcttcg tttcaactca aaaagagact cacttttggt
     2341 aaaatttagt cgaccaaaac gtcaccctac caaaggagtc tctc
//
LOCUS       DAIGSZ010000148         2263 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.154, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000148 DAIGSZ010000000
VERSION     DAIGSZ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.154"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(151..2148)
                     /locus_tag="NOB31_002883"
     CDS             complement(151..2148)
                     /locus_tag="NOB31_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HCI0975040.1"
                     /translation="MIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKA
                     LVTNKANQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHL
                     KEATKRLSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVY
                     IKNSGVTDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADE
                     AEKYLAKGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGS
                     NLMLSMNAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHE
                     QGSKEITENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKS
                     SVFNRSGQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRD
                     SFKEFGLGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYT
                     PIQLAQYASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMA
                     ILREGFHQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGP
                     TDNPEIAISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          576 a          506 c          411 g          770 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct tattttttct aac
//
LOCUS       DAIGSZ010000149         2232 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.155, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000149 DAIGSZ010000000
VERSION     DAIGSZ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.155"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..378
                     /locus_tag="NOB31_002884"
     CDS             <1..378
                     /locus_tag="NOB31_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HCI0975041.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="NOB31_002885"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="NOB31_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCI0975042.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..2026
                     /locus_tag="NOB31_002886"
     CDS             1859..2026
                     /locus_tag="NOB31_002886"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975043.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFTGSVAKF"
     gene            2080..>2232
                     /locus_tag="NOB31_002887"
     CDS             2080..>2232
                     /locus_tag="NOB31_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI0975044.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVREILYDRGINVSH
                     TTIYRWV"
BASE COUNT          628 a          371 c          483 g          750 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt ttactggttc tgttgcaaag ttttaaatct actatcaaat
     2041 aaggtagaat aatagaaaaa gatagcagga ggaatgacga tgaatcattt taaaggaaag
     2101 caatttcagc aggatgtgat tattgtagcc gtgggctact atcttcgtta taaccttagc
     2161 tatcgtgaag ttcgagaaat cttatatgat cgtggcatta acgtttctca tacgacgatt
     2221 tatcgttggg tg
//
LOCUS       DAIGSZ010000150         2125 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.156, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000150 DAIGSZ010000000
VERSION     DAIGSZ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.156"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..159
                     /locus_tag="NOB31_002888"
     CDS             <1..159
                     /locus_tag="NOB31_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HCI0975045.1"
                     /translation="RRNKFYRSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGIPA"
     gene            242..859
                     /locus_tag="NOB31_002889"
     CDS             242..859
                     /locus_tag="NOB31_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975046.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKFEQTFRSFLKNRVSQIFNLD"
     gene            1023..1355
                     /locus_tag="NOB31_002890"
     CDS             1023..1355
                     /locus_tag="NOB31_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975047.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
     gene            1679..1840
                     /locus_tag="NOB31_002891"
     CDS             1679..1840
                     /locus_tag="NOB31_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCI0975048.1"
                     /translation="MAYMVARTQKHKVGSLNGLQNHVDRKTKNHTNKDIDITKSGSVA
                     KFSKKSILV"
     gene            1872..2125
                     /locus_tag="NOB31_002892"
                     /pseudo
     CDS             1872..2125
                     /locus_tag="NOB31_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT          758 a          272 c          429 g          666 t
ORIGIN      
        1 cgacggaata aattttatcg aagtctccgg actgcctcat ccacgattaa ggggatggag
       61 accattcgag gaatatataa aaagaaccga agaaatggaa cgctcttcgg cttttcggtg
      121 tctactgaga tcaaggtatt aatgggaata ccagcctaag atatttggag ttcagagagg
      181 gcgcgtttga ttttcaaact tcgcaacaga accattattt taaagtggga ggaaaattgt
      241 tttgtggata tttaaacaag aaatctttgc taaattattt agtttagatg gattaggttg
      301 gggaatctta ttttttattt ttttattttt aggatctatg tggatctggt ttgttgataa
      361 aaaaaattct tatgagaaag taatagtgaa aaaaatgaat cgaaatgaat tcgatgattt
      421 ttcaaaggaa catagagttg aattgtacga tagtcatgaa attaacagta cttctccatc
      481 ttattattgg gtatttggtt gcgaagaaaa accattggag attaaattgt tgaaaatgct
      541 tgaaaatcct ccagtcattg aagatttttc tgcaaaaaac gttgaaaaac agatgtttga
      601 acaggtacaa ataagaggtc aaaacaaaat ttcattagaa ccagatgaat atgcagcctt
      661 ttttttagaa acaaattcag gtacttcaat gcctgttttc aaagttaaat taaaaatgaa
      721 tggtcgttta tgcacttatg atcttgttgc aaatatgcgc tatggttcta ctggtgatag
      781 acgtactatt ttaaaatttg agcaaacctt tagaagtttt ttgaaaaata gagtatccca
      841 aatttttaat ttggattgaa aaaattaaaa atttggccaa aaatactaca gttttttaga
      901 gcaatcatct tatgatgatt gctctttttt tgttgttttt gtgtcattcg ttgttcaaat
      961 cctctattcg taaaataaat attttaaact agaaatatgc cttattttta ggaggaatca
     1021 aaatgaacaa tagagaaata ttggcaaaag aaatggcgga tttgaaagca aaagaagcga
     1081 agattagagc gaaacgaaaa cagattagac agaaagaaat gatttcttta gcgaaattat
     1141 attgtaaaaa ggaaggcttt aagacacctg ctgaagcatt agattttttg gaatcaaata
     1201 aaagaaatca ttcagtaaat gatgaggttt tagtatcgct aagaaaattt gcagatggat
     1261 tagtttggca agaaaatggt gcatattggc gtacgaatga tgttaagggt ttgactcaat
     1321 ttatggcaca atttcgttca gaaaatgtga actaaattga ggaggggttg aagtgaaaag
     1381 caatactttt cacttttggt tttttgcgga ataaaaattg tgaaaacaat gacgcaaaaa
     1441 gccaatggtt ttgaacgaaa aaaggacgta aaaaaggaat gcgaaggcag tcgtttttcg
     1501 ttcgcttttt cgtttgagag aaacggagtt tctcatcggc tgttaagccg atatagccct
     1561 cggcagagct tacagacttt acgcagtata agtctagtaa gttatacctt acatggaggt
     1621 ttttccgaat ttagcttgtg attctcgcaa taattttaac gaaaggaagt acacagttat
     1681 ggcctatatg gtggcacgaa cacaaaagca taaagttggg tcgttaaatg gacttcaaaa
     1741 tcatgtagat cgtaaaacga aaaatcatac gaataaagac attgatatta cgaaaagtgg
     1801 ttctgttgca aagttttcca aaaaatctat tttagtgtaa aattgagaaa aaagacagag
     1861 aggatagagt aatgaatcat tttaaaggca aacaattcaa aaaatgacgt cattattgtc
     1921 gctgttagtt actacctgcg ttacaatcta agctatcgtg aagttcagga attgttatat
     1981 gatcgtggaa taaatgtttg tcatactacg atttatcgtt gggtgcaaga gtacagcaaa
     2041 gtcctcgatt atctttggaa gaagaaaaat agacaatcct tctattcatg gaaaatggac
     2101 gaaacctata tcaaaattaa gggac
//
LOCUS       DAIGSZ010000151         1953 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.157, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000151 DAIGSZ010000000
VERSION     DAIGSZ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1953
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.157"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..377
                     /locus_tag="NOB31_002893"
     CDS             <1..377
                     /locus_tag="NOB31_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCI0975049.1"
                     /translation="IEQPNLDRIKTARLEKKDKIVKNIASLDSDYFTELSNLYFSMTS
                     LLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKALNLNIDERKELESELFGN
                     LTQVQVNNLKREITARLISKLQ"
     gene            432..1598
                     /locus_tag="NOB31_002894"
     CDS             432..1598
                     /locus_tag="NOB31_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0975050.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
BASE COUNT          739 a          312 c          307 g          595 t
ORIGIN      
        1 ccatagaaca acctaatctt gatagaataa aaactgctcg tttagaaaaa aaggacaaaa
       61 tagtcaagaa tattgccagt cttgactcag attattttac tgaattatct aatctatact
      121 tttccatgac ttctttactt gaagtcaaac ttcaagaaga tgactccgac tttctttttt
      181 taaaaagtat tctagaggac tcctttgaat acacgattct atttgccaaa caaaagaagt
      241 ttattaataa agctttaaac ttaaatatcg atgaaagaaa agagttagaa tctgagttat
      301 ttggcaactt aacccaagta caggttaaca atctaaaaag agagataaca gctcgattaa
      361 tatcaaaact tcaataaaac taattattca atcagccaac tcgccaagtt atcagattgg
      421 agagattagt tatgtcaata caaaagtaca caacaaaaag cggtgcacga tatagtgtcc
      481 gcttgtatgt tcgtaaagat gaaaatggaa agcaagaata ctatgtaaaa aaagggttta
      541 aaactgaaaa agaagccaag ttacacgaag caagaaaaaa ggtcgagatt gaagataccg
      601 gctatcataa gccttctaat gacttgttta taacagtgta tgaagaatgg ttgccttctt
      661 ataggaatcg tgtacaagaa acgacatatc aacgtacaaa agaccttttc cgcttgcata
      721 tactaccaaa attcgggaat aagtccattt ctaagattac tcctgttcac tgtcagaatg
      781 cagtcaatga atgggcttta aaattcaaga atatcaaaca gcttaagtct tacagctctc
      841 aaatatttga gtatgccatt tttgcagagc tattacaccg aaatcctatg gcaaatacaa
      901 atctaccaaa gcgggaaaag aaagaaaatg aaaattactt ttcattagaa gaactaaaag
      961 ctttttggga tattctcaat aaagaagagc ctttaaaaca tattttaatc ttccagcttt
     1021 tgattactac tggtatacgt aaaggagagc tagctgctct tcattggtct gacatttatt
     1081 ttgaagaaca gctaatgtat gttagaaaga gctatgcaac tattcgaaat gaagagaaga
     1141 atgcaagaag aaaaactgtc aggattcaaa aaaatacaaa aaatatatct tccgaacgaa
     1201 tattaccaat tgatgcacaa actattgaaa tgttaaaaat ctggaaaaaa gaacaagctc
     1261 gagagctttt gcagtttggc ataaatacaa atacaaaaaa tcaacttatc tttacctatg
     1321 taaatgcaga cggtgacatt aatcaacctt tgcatgcgga ctattcaaat aatatattga
     1381 aacgtttaga gaagaaatat aaatttaagc acgttactat tcatggattc cggcacactc
     1441 acgctactct tctactagaa ggtggagcaa gtatcaaaga aacacaagat cgattgggtc
     1501 ataaaaatgc tgaaactacc cttaacactt attctcatgt tactgaaaaa gctcaacgaa
     1561 atgcgttaga aaaattcatt gcttacactg gtttataata ttgtcattac ctttctcatt
     1621 accagaacga aaaaaagaca ccttctcgca atgagaaagt gtctgaaatc gttggtataa
     1681 caacgattaa cgttttgaaa actgtgaagc tttacgtgct ttcttaagac ctggtttttt
     1741 cttcgtatca ttgaataagt ttgaaaagcc ttgatttata aaggtttttc cgtaaatata
     1801 ttttgttata tttgattaaa tttgaaatgt ttgtgttcta aaatgtgttc taatttaaag
     1861 gcagtatatt tcgtatttta tattaaattt ttaggctcat tcattctcaa atccattcta
     1921 tttagtcaat aaatatttta aaaagacttt ata
//
LOCUS       DAIGSZ010000152         1892 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.158, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000152 DAIGSZ010000000
VERSION     DAIGSZ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.158"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            194..497
                     /locus_tag="NOB31_002895"
                     /pseudo
     CDS             194..497
                     /locus_tag="NOB31_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(533..904)
                     /locus_tag="NOB31_002896"
     CDS             complement(533..904)
                     /locus_tag="NOB31_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975051.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(906..1307)
                     /locus_tag="NOB31_002897"
     CDS             complement(906..1307)
                     /locus_tag="NOB31_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975052.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            complement(1321..1728)
                     /locus_tag="NOB31_002898"
     CDS             complement(1321..1728)
                     /locus_tag="NOB31_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975053.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
BASE COUNT          600 a          312 c          261 g          719 t
ORIGIN      
        1 cacgtcttct gttgtgtttg ttattgcagg aaatcttaat atagaaggtt ttctatttgt
       61 ttacattttg ttgaattcga atttttttgg cacataattt ggcacaagta cttgttttct
      121 attattcagt atattaaatt ccgccttcac aaaaagaaca ttcgttcgta tactcttttt
      181 gaggtgaact tttatgctga tggaaggaaa aacacaatta tggtttaaat ttgacccttc
      241 gaatagattt atcaaagatt tttataaagt atggaattca gaagttttct ttttagcaat
      301 cgaagatagc ttattaatca atctctacta ttctaataag gaactatttc aaaattcctg
      361 ctgcgaaaac tagaatgaag aagggtgtat actttttgtt tgatatcgtg actgacgtgc
      421 cggacgcacg tagcgatcat cggcgttatg actatataaa gtatactttc gttgatccag
      481 aaagatacaa agattaaata aaaaaataac aaacaaactc gcttgaaatt cattaggtga
      541 gtttgtttat tattttttct gcttctcgat tcatcagcgc catatctgtt ttcgtaatgg
      601 tttcattagg aatatagtca gcacattttc ttttctctaa cattctatac ccactattat
      661 gtattcctaa ggtattcaat tccttaactg ttgaaaacaa attccaaacg gtttggtggc
      721 ttccttttcc gctacttcca ttataaataa tatcataatt ttctttcaaa tactcatcag
      781 attttttaaa agcactgtag tatgctcttg aaacagcagt tcttctataa gattctttag
      841 aattatattt atcatctgat tcaatttgtt tggaaataga taaatattca ttaaagtcaa
      901 acattttatt cccccaaagt tgctactaca gatttcccca tatatttata gtcagataat
      961 acattatcga gagtatccaa aacatcgtaa tctgaggaaa acaattcaga tgttgttttg
     1021 ataacaaaga aatacaagtt taaatcttca tcatatttta tattgatttc agcttttctt
     1081 tttaaaaccg tatttatcac atcaaaaatt ttgccatcat tacttgaaat tgtgttaatc
     1141 tcattttttg tagtaattac aagttgatta tcatttttag ttttcggagt agaacttgca
     1201 tccacaacaa ctggagatgc tagaattacc gatgcgcaag caaaaatcgc agcaaaattt
     1261 attaagctac cactccgatg tgtatttgat ggtactatat caagcatccg tatcgtctcc
     1321 ttaatttttt tccactggtt tgttgacctt gatatcaaag atttgccttc caatctcagt
     1381 tccattaaat ttaacaacag cataatgctc tcctgcttct tcaaccaaga catttctggc
     1441 gtttatatta aagtttatat cgttaacttg aggaggcaag cttaccgata cttcacccgt
     1501 agaaaaaatt tgtttttcat tcttgtttaa aacttcaatt tctactattt ttatcttttc
     1561 tgtatcctct atctcagaca ccacagctgt tacagaaaat gataaagcag taggaattaa
     1621 aggcgcatta atagaaagag ctggattaat tactttatta ataacattag tgccaaattg
     1681 ctgactttct acatcttctg aaattattaa ttgtactcta taagacattg atttctccta
     1741 atttttacat ttatttaata aatttatgtt tcacttttgc tagtcaattt agtttaacaa
     1801 tagtaacaaa gctttgtcaa cggaaatatt agctaatttt gtaagcatat ttataagtat
     1861 atttgtaagc atatctgaca tttaatcagt ag
//
LOCUS       DAIGSZ010000153         1656 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.160, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000153 DAIGSZ010000000
VERSION     DAIGSZ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.160"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(101..586)
                     /gene="vanZ"
                     /locus_tag="NOB31_002899"
     CDS             complement(101..586)
                     /gene="vanZ"
                     /locus_tag="NOB31_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HCI0975054.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(739..1650)
                     /locus_tag="NOB31_002900"
     CDS             complement(739..1650)
                     /locus_tag="NOB31_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HCI0975055.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT          532 a          317 c          224 g          583 t
ORIGIN      
        1 acacctacgg gcgagtttcc ccacatcccg ttttccatct aatccaattc attcaatatc
       61 tttatgtgta tgaaagatca gattgcttga tttagacatc ttacacgtaa tttattctta
      121 aatgggtacg gtaaacgagc aataatacga gcaaaagtat acctacaaaa ataataactc
      181 tgtctaattt tttttgattc atatgcttat tgcttaaacc atataatttc agtccaagaa
      241 agcctccaac agtatttgta attacatctg ttatgtctgt cgctccaata gcgaagataa
      301 attgaattat ttcaaaagta agacttaaaa ccagtacaaa agcaaactta ggtaaaaatc
      361 cgatttcttt aaaattgaca ttcaaaagca agccaaatgg aataaagatt ataacattat
      421 ctatcatctc tctgaaattc ccagtagcag taaatggagt caagttaaga cttctttgat
      481 gataattaaa tactgataaa atattgtatt gtaatttgaa taacactaac cagattagtg
      541 tcactaaata taaagctagc aatcctctag ataatatttt tcccaatata atttcctcta
      601 attcttttgt ttaagttgta tcattagtat agcaatgtcc tagttaacgt gggttttaaa
      661 ttaaaaagct aacgttaccc caaaagtgct agtacaataa tgctgttcat taatttcgtt
      721 ggtttcattc cgccatcctt acctccttga attagtatgt gttgatccgg gaaacactgt
      781 cacaattaca ccgtctatat tgtttcctga tatctcataa cgaagattag tcggcacatg
      841 aatggtggta tttttagtaa caggataata aaagatctca tatttttccc catttacact
      901 aacagaaatg gttttttctt cttttaggta atccatatat tcctcgagaa cgaaattctt
      961 ttctttcata atcgcactat gtggtaaacc aacatagcga atatgccatg gttcatattg
     1021 aattcctgtt aactctgttt tgtcctctgg ataacgtaaa atgaacccgt atttccaagc
     1081 attttcttct atccactttc cttcaggggc tcgttccatt ttcgtcaagc ttgatcctac
     1141 atctagtgat aaacctgaat tatgctcact ataacctgct ggtaaggcat actcagcccc
     1201 catttcttgg taaagcacac tttgctcatc aaagtctcga tagccactat taataataaa
     1261 atgactaacg ccacccttta cagcatcatt gaccatctct gaaaattttt gtgctatttc
     1321 ttttgacata taaatattac tatcaagcaa cccgtatcca tttattaatt cgtcatgttt
     1381 agataaattc acgatatctg acttcacact ttcttggcga acaggatatt tactattgat
     1441 taatagcaga tttccttgat aaacctgttc ttctgtaatt gttttctctt gggtattttc
     1501 agaagtccca ctattttcta aatgttcttt gggattttga tcataatttt gaaattcgac
     1561 tttttcctga gaaaacagtg cttcattaac gtagtcataa cctaagtata ttaagaataa
     1621 caataacaat aaaaaaaaca acttcttcat tttcag
//
LOCUS       DAIGSZ010000154         1599 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.161, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000154 DAIGSZ010000000
VERSION     DAIGSZ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1599
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.161"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            76..1395
                     /locus_tag="NOB31_002901"
     CDS             76..1395
                     /locus_tag="NOB31_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016372324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HCI0975056.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRQQYEEEKEKTFKAIRWDWERQREIYMSKLW"
     gene            1367..1564
                     /locus_tag="NOB31_002902"
     CDS             1367..1564
                     /locus_tag="NOB31_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975057.1"
                     /translation="MKFICLSCGEKESIPMDVVKFLDDADIANDPNNPPQFTCEKCGK
                     EMYPEYYRNALGIEFKISDVQ"
BASE COUNT          573 a          244 c          360 g          422 t
ORIGIN      
        1 gttaagggct aaaaaggctg cactaccagt cttttagccc ttttcatttt gtttttgaac
       61 aagtaaaata ttactatgaa agcgaatatt ctcgaagcaa tcttttttga cgaacaccat
      121 aattgggata actttgttga gaaatacggg cgaaagattc ggctagtcgt caaacgggaa
      181 gtaaacaagt ttagatattg tggagatatt caaaaaggat accgactgtt tgtctgcgag
      241 ggatgtcatc aaacaaagtt tgttcccttg aaatgtcgtg gaaagttctg tccaacgtgt
      301 gcaacaggtg aaagccaaag gtggtcagcg gttgtggcga atgatatgtt taaagtgaca
      361 catcggcacg taatctttac gatcgatgag gggttacggg aaatctttat gatggaaaac
      421 tatcgagatt ccttactgaa aggactaatg gatgaagccg caaaaattat tcttgcctat
      481 tttgagaaaa gaaaggtgaa ggcaggtata gtagctacaa tccacacctt tggatcaaaa
      541 ctagaattta atccgcatgt tcatatggtt gttactatgg gtggcttaac aagagatgga
      601 agttgggaag aatacgatta tttacctttt tctatgttaa gaaaatactg gaaaaatgct
      661 gtattgaaac taattagacg aacgttaggt gagtgggaca agcaaagagt tcaatcaaga
      721 ttacaagctg cgtacaagaa caatggagaa gggttttacg taaatgctcc taaaaggagc
      781 aggacaaatc taaagtcact actccaatac atcagtcgtt atatgaagcg tggcccgatc
      841 gcattaagcc gaatcttaat gtatgatggc gacactgtca tgttcaacta catggacaaa
      901 cgaacgaata ctaaagagac gatgaccatg agtatagacg aattcatagc tgcactgatt
      961 cgccatattc aaaataagaa tttcaaaacg attcgtcgct atggaatcta tagtcgtaga
     1021 atcaaaacat taatgaaaaa ggtcatgaag gagtatcaga aacgagtaaa aaagctgttt
     1081 atcaatctga atgaggcctt aagaccaaaa tcctgggaag aaagaataac cgaagaattt
     1141 ggtgaaaatc ccttagaatg ttcttgttgc ggtgagtact atgaattcgt tgggatgagt
     1201 gtgcgcaaaa atggacggtt agttattaaa tatgcgaaag ataaccatgc aaagcggttt
     1261 atgcgagagg agaatcgaaa aattgaccaa aaagaattca ggcaacagta tgaagaagaa
     1321 aaagaaaaaa cttttaaagc aattcgctgg gattgggaac gccaacgtga aatttatatg
     1381 tctaagttgt ggtgaaaaag aatcaatccc aatggatgta gtaaaatttt tagatgatgc
     1441 agatattgca aatgatccga acaatcctcc ccaatttacc tgtgaaaaat gtgggaagga
     1501 gatgtatcca gaatattata gaaacgccct tggaatagag tttaagatca gtgatgttca
     1561 ataagaaggt taatcataca aaaagtccac cggagaatt
//
LOCUS       DAIGSZ010000155         1450 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.162, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000155 DAIGSZ010000000
VERSION     DAIGSZ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.162"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            24..248
                     /locus_tag="NOB31_002903"
     CDS             24..248
                     /locus_tag="NOB31_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCI0975058.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            245..1270
                     /locus_tag="NOB31_002904"
     CDS             245..1270
                     /locus_tag="NOB31_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCI0975059.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
BASE COUNT          481 a          245 c          302 g          422 t
ORIGIN      
        1 actttattta gggagagaag aaaatgaata ataaaacgtt cgaagtacta aaatggttcg
       61 cactggtaat tattcccgca ctagctactt tcgtggggtt agttggtaaa gcgctcaatt
      121 ggcagtacac agatatctgt gttgtcatca ttactggttt tggcgcgttt ttagggagtg
      181 tgttgggtgt atcaaatcga acctacaaaa tgttctcggc tgaaagcgaa gaaggaggaa
      241 acaaatgaaa aagaaaatta ctattactgc gatgagcctg ttaacggctc tttttttatt
      301 acccattaat acgtttgctt atactattaa tgacgagtat aatttagcgc cgaatcaagg
      361 agactccaga ttagcaattc ctaacaaaat tattttgcac gaaactggaa tagatgcacc
      421 agcaagaaac gtagccgcca acatgaaaaa taattataac ggaagcaatt cttatactac
      481 agatgttatt ggtgacggtg ggattgttta ccgtgtgggt gagcaaggat atgtttcgtg
      541 gggagctggt aacgctaatc cttatgcgcc tgtacagatt gaattacagc gcacatatga
      601 taaagcattg tttgaaaaaa actatcgagc ttatattgaa tatacaagag atagtgcaaa
      661 aaaatatgga attccattga ctcttgatca aggaacttct ttatttacaa aaggaatcat
      721 ttctcatttg tgggtgacaa attatgtttg ggggaaccac acagatccat atggttactt
      781 atcgcaaatg ggagttagca aagaaaagct tgcttatgat ttagctcatg gatttaccga
      841 tgaaaatcca acaacttctg aaaacaagcc tgtcattgat ccaacacgag ctggtgcagc
      901 taatcctacg ctgacagatg gaacaaatca cgcccacatt gatcagtttg gggaaatcga
      961 aaacgcaaac ttgcatgtgg ctggatggca cattgctaac tataaatacg agtatatttt
     1021 cattatggac tacaatactg ggaaagaatt agctcgagta agagctgatg gaatttatag
     1081 accagatgta aaccaagctt ataatacttc tggaaatgtt ggttatcatg tatctttcaa
     1141 tatgcgtaat tttcctagta agaaagtcta tgtaatgatg cgggcaacga atgatccaga
     1201 gggaaacact aaaggcggtg cgcaagattt ccatgacaaa cgttggtatt taaatattcc
     1261 taaacgataa aaatagctcc tcgttgagga gcagtacata actatattga caactataaa
     1321 aattattcga taaaatagtg atgttatcgc atatcttcac tatcacccat aaatagtcac
     1381 actccaagct atgcgataac aggtttgttg ccacacattc tactggttga ttgtttatgg
     1441 ctttatgtgg
//
LOCUS       DAIGSZ010000156         1424 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.163, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000156 DAIGSZ010000000
VERSION     DAIGSZ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.163"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(150..1337)
                     /locus_tag="NOB31_002905"
     CDS             complement(150..1337)
                     /locus_tag="NOB31_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HCI0975060.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAIGSZ010000157         1394 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.164, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000157 DAIGSZ010000000
VERSION     DAIGSZ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1394
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.164"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            9..419
                     /gene="spx"
                     /locus_tag="NOB31_002906"
     CDS             9..419
                     /gene="spx"
                     /locus_tag="NOB31_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCI0975061.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            433..789
                     /locus_tag="NOB31_002907"
     CDS             433..789
                     /locus_tag="NOB31_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HCI0975062.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          510 a          208 c          261 g          415 t
ORIGIN      
        1 gtgagaaaat gataaaagta tatacttcgc ctagctgtac ttcctgtaga aaagcaagag
       61 catggttgca agcgaatcaa cttgaatttg aagagaagaa tatttttgcc gaaccgttaa
      121 cagaaagtga gatcaaaaag atcttggcag cgactgaagg aggagttcaa gatattattt
      181 ccactcggtc gaaaatttac gaaaagctgg gcatagattt taacgaatta actttaaagc
      241 aaatgatcgt cttattcaaa gaatatcctt cattattgag acgacctatt ttgattgatg
      301 aaaaaagaat actaatcgga tttaatgaag atgagatccg gtcatttgtc cctcgtgaaa
      361 ttcgatgtgt tgccagaaat ctgatctatt tacaaaacaa taacatctta aattcatagg
      421 gagggagcct tcgtggaagt gaaagtctat ggatcagcgc actgtgtaac aagtctgaag
      481 gcgaaacaat ggttagaaca ccatcaattg ccttatcaat ttgttgactt agaagaacgc
      541 gatttaagta cagaagaagc agaagaatta tgcagttttg aagaagtgca agcagaacag
      601 ctatttgcga cttggtctga ggcttttcac aacattgcga ttgacctttc ctgtgtagga
      661 aaaaaacaac tgattttttt atgcacacaa cataccaatc tcctcagacg tcctttgatt
      721 attatcgatg aagttctatt tattggatac aatgagcagt tgatggaaca gcttatctta
      781 aataaataga ctttaactgt tttaatcaag tcactgagca tttcatacag ttgtaacagt
      841 cgaacactta gcatcaagcg tgttatgtgt tctttttttg actttatttt tctactatag
      901 agacatgctc aatttatgtg gtcaaaattc aaatctaggt ggggatatag agttaaaaat
      961 atattgacat gtgtaaattt acatgatata ttcatttctg ttgttttaag tagcaaagca
     1021 ataaaatagt attttaaaaa acatataaaa tagttgttga catgttagaa atgacatgat
     1081 aagataactg agttgttaaa aaagaaccac ttgtgaagct tgattctatc gaaaaaaact
     1141 tcaaaaaagt tcttgacaaa taacaaatga taagttatga taaatgagtt gctgtaagat
     1201 ttcgaaaaac gaaatcaaaa aaacttttaa aaaagagttg acaattactt gtctctctga
     1261 tatgatataa aagttgctac ggcagccaaa aacgaatcgg ggaacactcc tgatgaagta
     1321 gacctttgaa aactgaacaa agtaagacaa accaaatgtg tagggcgtct tgattcaatt
     1381 caagacaaca aaca
//
LOCUS       DAIGSZ010000158         1338 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.165, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000158 DAIGSZ010000000
VERSION     DAIGSZ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.165"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..928
                     /locus_tag="NOB31_002908"
     CDS             <1..928
                     /locus_tag="NOB31_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975063.1"
                     /translation="ELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEI
                     FIQGENYFTKILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNS
                     IFKKKIDDYFVYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFF
                     DQPLLSDGYGIDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVL
                     LLENDFSSTLLISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIV
                     LFCEHYNRLSEEKILLPENWAELRKLVEYGII"
     gene            915..>1338
                     /locus_tag="NOB31_002909"
     CDS             915..>1338
                     /locus_tag="NOB31_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HCI0975064.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSY"
BASE COUNT          476 a          169 c          194 g          499 t
ORIGIN      
        1 agaattaggg ctatttaatg atgttgtttt tgtgaatcac cggaaaatcg gttcttcctt
       61 taaacgtaaa attaacttgt taactaacca taatcaattt ttctcggatg atttatccgt
      121 ttatgatgaa atttttatac agggggaaaa ttatttcaca aaaatacttt tctccaatgt
      181 ttacaaaaaa aatccagatg taaaactaaa ttatatagaa gatggtttgg gtacttattt
      241 gaagaagagt atattttcaa caagtaaaaa cgttcaaaga gtttttaaaa tattaaataa
      301 aaatagcatc ttcaaaaaaa aaattgacga ttattttgtc tattgtccgg aattgttact
      361 ttatgatgta aaaaatataa aaaaaattcc caaaatagat gaaaacagta aattgatgaa
      421 aaacatacaa tcaatctttg ggatagaaga agtttttgtc ggagataaat gtatcttttt
      481 tgatcaacct ttattatctg atggttatgg catagatgaa acagatattt tcgctaaagt
      541 aaatagtata ttttctggaa aaaaagaaac tttaattaag cttcatccta gagcaaggac
      601 aaatcgttat ggtgaaaaaa acatattgaa ttccagttta ccgtttgaag tcttgctact
      661 tgaaaatgac ttctcttcaa cacttttgat tagtcctata tctacaattt ctttttcacc
      721 atctatgatg tttgaaaaga cgatcaactc tattatgttg gctaaattaa ttttaaatga
      781 atatacagca ttatctgaag ataaaaaaga aacattgaca aatattgttc ttttctgtga
      841 acattataac cgtctatcag aagaaaaaat tttactccca gaaaactggg cagaattaag
      901 aaagttggta gagtatggga ttatttaaca cactttccaa gtcaaaatta gttaagtcca
      961 gtttctggta tactataggg aattttttta ttaagggaat ttcattcata actattccta
     1021 tttttgtaaa tattactact caagcagaat atggtttgat taataatttc acttcatttg
     1081 tatcaatttt ttcgattctt gttgggctaa gcctaaattc ggcaattaat aatgcaagtt
     1141 ttgactataa agatgacata aatgaattta tgtcatcggt actttctcta gctacacttt
     1201 cgttaattgt gttcttatta atagggaaca tatatttttt gttttcaaat gctttttttg
     1261 atatgaacca acttgtattt aatttgatgt tattacaaag ttttgctagt tttgtaatta
     1321 gttatatcca gtcttatt
//
LOCUS       DAIGSZ010000159         1294 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.166, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000159 DAIGSZ010000000
VERSION     DAIGSZ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.166"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..1244
                     /locus_tag="NOB31_002910"
     CDS             <1..1244
                     /locus_tag="NOB31_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HCI0975065.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DAIGSZ010000160         1247 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.167, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000160 DAIGSZ010000000
VERSION     DAIGSZ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.167"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            200..742
                     /locus_tag="NOB31_002911"
     CDS             200..742
                     /locus_tag="NOB31_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975066.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1247
                     /locus_tag="NOB31_002912"
     CDS             898..>1247
                     /locus_tag="NOB31_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HCI0975067.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          515 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccaga
//
LOCUS       DAIGSZ010000161         1231 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.168, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000161 DAIGSZ010000000
VERSION     DAIGSZ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.168"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>1231
                     /locus_tag="NOB31_002913"
     rRNA            <1..>1231
                     /locus_tag="NOB31_002913"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          323 a          280 c          375 g          253 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc c
//
LOCUS       DAIGSZ010000162         1219 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.169, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000162 DAIGSZ010000000
VERSION     DAIGSZ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.169"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..460
                     /locus_tag="NOB31_002914"
     CDS             <1..460
                     /locus_tag="NOB31_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HCI0975068.1"
                     /translation="LLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTTLFVSV
                     IYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGLLPKFM
                     KVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            469..696
                     /locus_tag="NOB31_002915"
     CDS             469..696
                     /locus_tag="NOB31_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCI0975069.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          377 a          195 c          204 g          443 t
ORIGIN      
        1 attgctatta aaatttgtcg ttttaggtat aagtgccgta tttattttgt tcggcgtact
       61 tttttatact cagatcgcta caagcgaaaa aggattcaat tttgattggc agaccacatt
      121 atttgtttct gtcatttact ttgcccttct cctagggatc gttattgctt atttcttatt
      181 gaaactattg aaaaaaatcg aagataacca agctttttcc actcaaagct taaacatact
      241 aaaaaaaatc gaacgaacca ttttgtttat tggtttcgcc ttttttggct tacttcctaa
      301 atttatgaaa gtagcggatt tagacgatgc tccaggtttg atgttggtag gaatcgctgt
      361 cgtattcatt ccttttgcag tatacacatt aacaagcgtg ctggaaaaac tgcttgaaca
      421 tgcgatttta cttaagacag atcatgattt gacagtgtga ggtgcgacat ggcaattatc
      481 gttaatttag atgtagtatt agctcaaaaa aaaatgagtg tgactgaatt gagtgagaaa
      541 gtgggcatta cgatggcaaa catctctatt ctaaaaaatg gaaaagcaaa agccatccgt
      601 ttttccactc tcgaaaaaat ctgccaagtt ttggagtgtc aaccaggtga tttgttgacc
      661 tataaaaatg actcgaatac tataccagaa gaataaaata aagtagaaca aacagtaaat
      721 aaaaaataat ctgaatgata gatgtgtgag acttttagaa gttatttacg tctattattc
      781 agatttttta tttcgattga ataccgtttt atctataaat aagatatgta ctgactcata
      841 caaagggggc cttttcttct ccatgtacta tcacttttcc tgatacaact ggtttcctgt
      901 tacgttgtag ttggatctgc ttttagtata atactttatt cattccacca gactgatagc
      961 agtttgagca gtctaaataa tcatgtagta ttacaggcca ttctgtttca taccttgaag
     1021 tgcttaaaac ttcagctaat ggcccattgt gttaactctt actccattct tttttagtaa
     1081 gctcccatat atactgtaaa gccttctata tattatgtca tgttgctttt taacatttac
     1141 tatgtagttt tgataaaatg atttgaataa cagtgatgga caattctttt ttatttttaa
     1201 cattattttg ataataatg
//
LOCUS       DAIGSZ010000163         1195 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.170, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000163 DAIGSZ010000000
VERSION     DAIGSZ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.170"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..1076
                     /locus_tag="NOB31_002916"
     CDS             <1..1076
                     /locus_tag="NOB31_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCI0975070.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DAIGSZ010000164         1190 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.171, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000164 DAIGSZ010000000
VERSION     DAIGSZ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.171"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            143..400
                     /locus_tag="NOB31_002917"
     CDS             143..400
                     /locus_tag="NOB31_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975071.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(632..1063)
                     /locus_tag="NOB31_002918"
     CDS             complement(632..1063)
                     /locus_tag="NOB31_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HCI0975072.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          147 g          439 t
ORIGIN      
        1 ttttctgtcc acgttcattt tactccaaag ttttcctcat ttcaaaagaa aatcacagaa
       61 tacacgaaga agcgtttcta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt attactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaataa
      481 attttaaatt tattgtccat aatgttatta tgaatttata gcattaagaa aagagataag
      541 actttacatt tttttaggaa tgtaaagtct tatctctttt cttaattgta caattagtat
      601 tatctgcact actttctaat taaataaatt tttagttatt aacttgatta aaatcagaga
      661 taatatcatt taattcagtt tgaagggttg taacgattaa atggaaattt tcttcatctg
      721 ttttattata tggggatgtt ttcgttatat ataacaactt ttctttttca attttcatta
      781 ataactctgt cgaagtctgt actttatctt gataattaaa tgcagacata ccactttgta
      841 taattgtaat tattgctgaa gcaattgaaa caatcaatag taaagacctg tgttcggaag
      901 cctgatcaat taatattggt atactagctg ataagactat ttttataata tttccgatac
      961 caattactct attataaaat cgaatttctt tttttaatct atcgattgta gaatcaatag
     1021 attcgataaa cgctttttga tccatcattt tctctccaat cattttatta aaatcattaa
     1081 caaaaatatt ataataggat ttaagtaagt tctaactaat cacatataaa aataaaaaaa
     1141 catttgtatt ttatcaaagt tttattatac ttgtcaattt gtgtacatcc
//
LOCUS       DAIGSZ010000165         1124 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.172, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000165 DAIGSZ010000000
VERSION     DAIGSZ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.172"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(206..760)
                     /locus_tag="NOB31_002919"
     CDS             complement(206..760)
                     /locus_tag="NOB31_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0975073.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADVAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          362 a          218 c          130 g          414 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatacttcc gaaaattcag ttatcttcat taatctcacc ttctaagttt tcattataca
      181 caaaaaatat atcctaatat ctcaattagc ctcccaattt aaaaccacgt aacgatgccc
      241 ctatttcatc ttcagttata ccaatgtacc tttttgtaat tgcttgcgag ctatgattaa
      301 aaataaacat taaggtagca atgtctctag ttttcttgta gtagtgatac ccaaaagttt
      361 ttcttaatgt atgtgttcct atatcatctc ttcctaattt ttctgctaca tctgcatata
      421 tctgatagac acgatccctt gttatatgtc gaccttgttg ccgacttgga aataaccaat
      481 cattttcttc tttaccttca gtatataata aaatctcttc tctcaaatta tctataaaaa
      541 tcggttttcg cttacctgtt ttatgttcaa caataatagg cttactttta cctcgtatgt
      601 ctccaacttt taatcctata atatctgaca tacgtaaccc attattgatt ccaaacaaaa
      661 ataaaaaact atctctttct ggattacttg ttcttcttag ccaaaactga aaatcttgta
      721 tctcttcatt tgtccttaac ggttgtacat tatagctcac tattgtttcc cttcttaaaa
      781 atattctgag ttcatgatta tatatatatt ttaccataat catgaactta tatatatact
      841 ctgttaaaag tgaagaaaat caaggggttt agtttatgat tttatatcat ttcagtaact
      901 cagaatattc cgactttttt gtacaaaaaa attaacctta cttatatgaa gattctaagc
      961 tcttatttaa attttagacg ggcagttatc cgtagaagtt cttagaatag ctaatttaca
     1021 taattaaatt atatgaaatt taagtttgaa caatatacta agaactcccc ttactataaa
     1081 gtgaaataaa ttagcatatg aataaccgtg ctaccaaact tttc
//
LOCUS       DAIGSZ010000166         1111 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.173, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000166 DAIGSZ010000000
VERSION     DAIGSZ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.173"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(162..235)
                     /locus_tag="NOB31_002920"
     tRNA            complement(162..235)
                     /locus_tag="NOB31_002920"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(199..201),aa:Ile,seq:cat)
     gene            complement(790..1104)
                     /locus_tag="NOB31_002921"
     CDS             complement(790..1104)
                     /locus_tag="NOB31_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975074.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          418 a          174 c          170 g          349 t
ORIGIN      
        1 ttcaaatata cagaagtata actatgtgaa acatcctttc attaatccat aaaaggatac
       61 ataaaaaagc cactcatttg agtggcaatg aagaaaagct ttagcttgta taatactctt
      121 caaaaaattc taacacagaa cgattcaatt ggctacatta atgtaccctg taggactcga
      181 acctacgacc ggacggttat gagccgtctg ctctgaccaa ctgagctaag ggtagtggtt
      241 gttgccacat aaagccataa acaatcaacc agtagaatgc gtggcaacaa acctgttatc
      301 gcatatcttg gagtgtgact atttatgagt gatagtgaag atatgcgtct ccatatatgt
      361 atggttgaga cagataaaca tgtatgaaaa acgttgttaa atcaacgttt ttttattttg
      421 gtcaaggaga gaaaagtaga gaaatacaaa attttttgca ttgattttgc attcaaaaaa
      481 acattcaaac atttagaaat ccccaatacg tattcaggaa aatctatttt aaggtttaca
      541 aaaagaactt ttgttcgtac actctttttg aggtgaactt ttatgctgat ggaaggaaaa
      601 acacaattat ggtttaagca tgttccttca aataagtttt ttaattataa actctagaga
      661 aattaattca tcctaacata aaataattgt tcactcaaaa gtttttctag aacaattaaa
      721 acagcaggct tcacattcgc tatacatttg taagaagtaa taattcctgt actaaaaggc
      781 ataattgctt taattatttt ttgacttctc ttcaaacaca agaagtagtt gtgtaataat
      841 tgcagaaata aggattccaa taatagatat aaaatttgac atggaaacgt ctataacatt
      901 aaaagaataa agtgttgaag aaagtaaact gattgaaata acccctccgt aaaaaatagt
      961 ctgtgaatat acccactttt tttcagaaga cgtacttcgt ttggttctaa aacctatccc
     1021 tgcatttcta ctcttatcaa aaaaccaaat atttagaagt aataatattg ctattattaa
     1081 gataaaatta ctgtaaaaat ccaaaagcta t
//
LOCUS       DAIGSZ010000167         1105 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.174, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000167 DAIGSZ010000000
VERSION     DAIGSZ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1105
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.174"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..1087
                     /locus_tag="NOB31_002922"
     CDS             <1..1087
                     /locus_tag="NOB31_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCI0975075.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT          402 a          192 c          214 g          297 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaa
//
LOCUS       DAIGSZ010000168         1091 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.175, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000168 DAIGSZ010000000
VERSION     DAIGSZ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.175"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="NOB31_002923"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="NOB31_002923"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HCI0975076.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          135 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta a
//
LOCUS       DAIGSZ010000169         1061 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.176, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000169 DAIGSZ010000000
VERSION     DAIGSZ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.176"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(39..995)
                     /locus_tag="NOB31_002924"
     CDS             complement(39..995)
                     /locus_tag="NOB31_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975077.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          381 t
ORIGIN      
        1 ttttagaaaa agcagtcgga ctttctaaaa gaagttcact attcgatcct gtcgatgatt
       61 tcttcaggaa aatcgtctat ttgcttgtca attttgctgt ctttgtattt ctcttcttgg
      121 atagtcaaca aaatctttgt aagattcccc cagtctactg ctcttggcgg atcgagccaa
      181 accactactt gagatgcact ttcttcatat agattattcc tattcgtgat tataacatcc
      241 gggaactcag gctttcctgc ctctatcact tccgtgttca gattaatgta caagcttaaa
      301 tttttcttga taaattgatt ataggcagca ccataagaaa aatcgatgat gatctttact
      361 ggttcagaaa tcagttgaat gggtatgtga ttgatcaata ataataaata actgaaaaaa
      421 agaaaaaatt tatcttgaag caactctttg cgttttgacg ttagatcatt tatatactct
      481 atcaaatagc aataaaatgc tggatagttt tctctaaaaa aagaaacatc aagtggaaat
      541 tcatcagctt tattaatagt gtaatgcaaa agtttaaaat gtattttggt taactctctt
      601 cggatcaatt ggctcgtctc ttctcgcaac agattaaact gattttcaaa actttcaatg
      661 aatcgttcat tcaaccattc gattgtttca tcttcatttt ttctcaagta tttttgatcc
      721 aatttatcat gaagataaag ccaagagagt gtcttattga taaaaataac ggatttttct
      781 cctaatactc cttttaagtg gtaaaatcct atatccgaaa aaaatagcga ctgattgcta
      841 gcaatatcta aagaatcagc ttgttcagcc aacaggttga ttgctaaaaa gtggaataat
      901 ttcttttttt cataagcaga cagaggataa tactgtttta aatcttttaa cattttttct
      961 gtttttataa ttataggtag cgtatacaat tccacaaaac ttatctctgt tgagttaaaa
     1021 agattatata aaaaaagccg aatgttttta ggattccctg t
//
LOCUS       DAIGSZ010000170         1004 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.177, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000170 DAIGSZ010000000
VERSION     DAIGSZ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1004
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.177"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>1004
                     /locus_tag="NOB31_002925"
     CDS             <1..>1004
                     /locus_tag="NOB31_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0975078.1"
                     /translation="GKKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLVTP
                     FCFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPRCL
                     LFDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHYIV
                     TDMNAPYFSLVKECFPNAQVIVDRFHIVQHLNRFFDAVRKRVMKTLDQKDPIQAKQYR
                     QLKSLFKLLLKSEDRLDYNTLTKRRNFNWRLLTETEVVDRLLKISPELKTAYRYYQDL
                     LTAYQEKDPDTFFQLLRAMPGEVPLELHHIKKAFFKYEKGIRLALLKKYSNARLENLH
                     "
BASE COUNT          301 a          209 c          191 g          303 t
ORIGIN      
        1 tggcaagaag atctctatga ttctcctgaa tcgtagcggt aataaacgga cctatcttcg
       61 gttgaagaaa cagcgatacc tctgccgagc atgtaaaaaa tattttaccg ctcggacgta
      121 tctcgttacc ccattctgct ttatttctaa gcagattcat tacaagatct tagaagaatt
      181 gacagagcgt caatctataa aagcaattgg taaacattgc gatgtttctg tgacaactgt
      241 tcagcggaca ttgtccgcct tgtcatcaga tatccgtcag aatcttgagt atttacctcg
      301 gtgtctatta ttcgatgagt ttcgttctct ttctacatgg cacggtaaat tttctttttc
      361 ttgtatggac ggtgagaccg ggaaactgtt tgagatctta cctagccgcc gtaaaaaaga
      421 tctcgttgct tttttcatgc gtttttctct caaagcgagg ttgggtgtac attacatcgt
      481 aacggatatg aacgctcctt atttctcact agttaaagag tgttttccaa atgcacaagt
      541 gatcgtcgat cggtttcaca ttgttcaaca tctgaaccgc ttcttcgatg cggttcgaaa
      601 acgtgtgatg aaaacacttg atcaaaaaga cccaatacaa gctaaacagt atcgccaatt
      661 gaaatcctta ttcaaattac ttttaaaatc agaggatcgt ttagattaca atacactaac
      721 gaaaagacgc aatttcaatt ggagactatt gactgaaaca gaagtagttg accgccttct
      781 aaagatttct cctgaactta aaacagctta tcgttactac caagacctgc ttactgcgta
      841 tcaggaaaaa gatccagata cttttttcca gctgcttcga gcaatgcctg gagaagttcc
      901 attggaactg caccatatca aaaaagcctt tttcaaatac gagaaaggga ttcggctggc
      961 attactgaag aagtattcga atgcacgact ggaaaatctc cata
//
LOCUS       DAIGSZ010000171         1000 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.178, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000171 DAIGSZ010000000
VERSION     DAIGSZ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.178"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            369..1000
                     /locus_tag="NOB31_002926"
                     /pseudo
     CDS             369..1000
                     /locus_tag="NOB31_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DAIGSZ010000172          976 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.179, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000172 DAIGSZ010000000
VERSION     DAIGSZ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..976
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.179"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            82..>976
                     /locus_tag="NOB31_002927"
     CDS             82..>976
                     /locus_tag="NOB31_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HCI0975079.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHY"
BASE COUNT          331 a          182 c          192 g          271 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatg
//
LOCUS       DAIGSZ010000173          945 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.180, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000173 DAIGSZ010000000
VERSION     DAIGSZ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.180"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            28..>945
                     /locus_tag="NOB31_002928"
     CDS             28..>945
                     /locus_tag="NOB31_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0975080.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVF"
BASE COUNT          339 a          171 c          181 g          254 t
ORIGIN      
        1 cgaaagaatt ataaggagtg agtacaaatg acctataacc atcttacacc aactgaactc
       61 gtaatgatag aagcttattt caatcaatca caacctgttt caaaagtagc caatctgtta
      121 caacgttctc gacaaactat ttataaggtc tatcgttttc ttaaatctgg tggaagcgca
      181 atgagctact ataaacaata taagaaaaac aaacgtaact gcggaagaca tccgattgtt
      241 ttacctgatg agcaacagga atacattcaa aaaaaggttg ttcaagggtg ggctcctgat
      301 gtccttattg gtcgagcaga gtttcctatt gcttgttcgg tacgcacact gtatcgaatg
      361 tttaaagata aaacctttga cactcacgat ttaccaatga agggaaaaag aaaaccaaac
      421 ggtcataaag aaaaaagagg aaaacaaggg tttcgccggt caatccgaga cagaaagaca
      481 gactataccc agtttgatca tgaatttggt cacctggaag gtgacactat cgtgggtgga
      541 aaacataaaa gcgcggtcat cacattagtt gaacggctat ctaaagtcat cattaccttg
      601 aaacccgaag gcagacaggc taaagacatt gaaaataggc tgaatcaatg gtttcgttgt
      661 gtcccaaaaa acttatttaa atccatcaca tttgattgtg gaaaagaatt ctcaaattgg
      721 aaaaagatta gtaataccaa cgatatttca atttattttg cggatccagg aacaccttct
      781 caacgaggat tgaatgaaca ttcaaatggc ttattacgta aagatggttt gtataaagct
      841 atggatttta atggtgtatc tgaaaccttt atccaatcgg tggcatcgaa acgaaatcat
      901 attcctagaa aatcattaca ctatcggaca ccaatggaag tattt
//
LOCUS       DAIGSZ010000174          910 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.181, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000174 DAIGSZ010000000
VERSION     DAIGSZ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..910
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.181"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..888
                     /locus_tag="NOB31_002929"
     CDS             <1..888
                     /locus_tag="NOB31_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HCI0975081.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          389 a          120 c          149 g          252 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt caacttttgg
      901 ggttcagttc
//
LOCUS       DAIGSZ010000175          901 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.182, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000175 DAIGSZ010000000
VERSION     DAIGSZ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.182"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
BASE COUNT          348 a          103 c          113 g          337 t
ORIGIN      
        1 attagcaata tataaaagaa ggtatcaaga gtcacagtga atttattccg aaaagtgaaa
       61 agagcaaata taaaatttaa taaaaataag aactaaatag gaaaacgtag acgtaatttt
      121 ctacgttttc cttttcatat atattaaata ttacggaaaa ttatataaac taatttagtg
      181 ttttgtttgt aattcctaat tttgctccac ttttagataa tttttaggtc tatttaactc
      241 attagacatt ctatgctcat ttttctccaa atttgtttca actctttcgt acttaatttt
      301 gcgtatttga aaattcttct tttagagtac ttttattacg atactagtat gatatatatc
      361 tacagcaaac agttaaaatc ttcctaaaat aagcgaatag cattcctaaa acctataaaa
      421 tttttagatg aagcgacaag tggacaatta ataaactact tgaacatgaa attatggatc
      481 acctttcaaa tttagaaaat ggaattctta tacttattgc gcaacattta ttgattgcaa
      541 aattatgtga caaaaagaac tagtagaaga aggaataatg gcttgataat aaagtactac
      601 ctattaaagg tagtacttta tttaatttag tataaattaa catactacta tattttaggt
      661 ttcatattat ataaattaat aatatactac catttgttgg tagtataatt taaaggtaat
      721 aagttattct tttattacta tgtttgggtt ttatagcaaa gaaagtttaa taagagtttg
      781 gacctagcaa acaatattaa tgaggtcatt aaatcttatt atctttagtg atataatgaa
      841 atatctacac gacaaaatta tgatcttgcg taaagttata aaatattaat aaaaatattt
      901 t
//
LOCUS       DAIGSZ010000176          881 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.183, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000176 DAIGSZ010000000
VERSION     DAIGSZ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.183"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(68..140)
                     /locus_tag="NOB31_002930"
     tRNA            complement(68..140)
                     /locus_tag="NOB31_002930"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(105..107),aa:His,seq:gtg)
     gene            complement(143..216)
                     /locus_tag="NOB31_002931"
     tRNA            complement(143..216)
                     /locus_tag="NOB31_002931"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(182..184),aa:Trp,seq:cca)
     gene            complement(223..303)
                     /locus_tag="NOB31_002932"
     tRNA            complement(223..303)
                     /locus_tag="NOB31_002932"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(267..269),aa:Tyr,seq:gta)
     gene            complement(305..380)
                     /locus_tag="NOB31_002933"
     tRNA            complement(305..380)
                     /locus_tag="NOB31_002933"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(345..347),aa:Phe,seq:gaa)
     gene            complement(416..488)
                     /locus_tag="NOB31_002934"
     tRNA            complement(416..488)
                     /locus_tag="NOB31_002934"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(453..455),aa:Asp,seq:gtc)
     gene            complement(498..570)
                     /locus_tag="NOB31_002935"
     tRNA            complement(498..570)
                     /locus_tag="NOB31_002935"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(535..537),aa:Val,seq:tac)
     gene            complement(586..657)
                     /locus_tag="NOB31_002936"
     tRNA            complement(586..657)
                     /locus_tag="NOB31_002936"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(622..624),aa:Glu,seq:ttc)
     gene            complement(672..761)
                     /locus_tag="NOB31_002937"
     tRNA            complement(672..761)
                     /locus_tag="NOB31_002937"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(725..727),aa:Ser,seq:gga)
     gene            complement(801..874)
                     /locus_tag="NOB31_002938"
     tRNA            complement(801..874)
                     /locus_tag="NOB31_002938"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(838..840),aa:Asn,seq:gtt)
BASE COUNT          247 a          243 c          201 g          190 t
ORIGIN      
        1 cgaaccaacg catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa
       61 taaaaagggc gaatgatggg aatcgaaccc acgaatgccg gagccacaat ccggtgcgtt
      121 aaccacttcg ccacattcgc catggcaggg gcagcaggaa ttgaacccac actaacggtt
      181 ttggagaccg ctgttctacc tttaaactat gcccctataa aatggaggag agtggattcg
      241 aaccactgaa ccctaaggaa cggatttaca gtccgtcgcg tttagccact tcgctactcc
      301 tccatggtgg cgcgggacag aatcgaactg ccgacacacg gagcttcaat ccgttgctct
      361 accaactgag ctaccgcgcc atattttaaa attattaatt gaataacaag aacgacggtt
      421 ccgacgggaa tcgaacccgc gatctcctgc gtgacaggca ggcatgttaa cccctacacc
      481 acggaaccag ttcattatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg
      541 cagatgctct cccagctgag ctaaacctcc aacattcaat taaaatgacc cgtacgggat
      601 tcgaacccgt gttaccgccg tgaaagggcg gtgtcttaac cgcttgacca acgggccagg
      661 taaatttgct acggagagta agggattcga acccttgaga cagtttggca ccatctacat
      721 gatttccaat catgctcctt cggcctctcg gacaactctc cagagtgaaa gaagctcaat
      781 actctttctc aaaatgagaa ctccggcagt aggactcgaa cctacgacat catgattaac
      841 agtcatgcgc tactaccaac tgagctatgc cggaataaca t
//
LOCUS       DAIGSZ010000177          862 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.184, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000177 DAIGSZ010000000
VERSION     DAIGSZ010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.184"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..434)
                     /locus_tag="NOB31_002939"
     CDS             complement(<1..434)
                     /locus_tag="NOB31_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0975082.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHR"
     gene            complement(451..855)
                     /gene="tnpA"
                     /locus_tag="NOB31_002940"
     CDS             complement(451..855)
                     /gene="tnpA"
                     /locus_tag="NOB31_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HCI0975083.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          260 a          139 c          136 g          327 t
ORIGIN      
        1 tgtctatgaa gcttaattct tactaatgac ttcaatttag gaactttgat gaatttacta
       61 tcaatcaaag caactgtacc attttgatta ttcgttgtat aactctgaac aggatttttc
      121 ttacttttga aacgtggaaa tccaacggat ttatcccgaa aaaaattctt gtatgcttta
      181 tctaaattaa gttgggcatt ggctaaagca aggctatcaa tttctttcaa aaacggaaat
      241 tctttcttgt atttagctgg tgtcggaaaa gtcatttttt tagaagaatc atttttaact
      301 tcttcatacg ccttttttcg gtcatcaagc attagattgt agaccttacg gacacaacca
      361 aaagatttgg caaagaagat ttcttgttcc tctgttggat agattctgaa tttgtatgct
      421 tttagttgtt ccataaagtt cacctacttt ctatttatga ttgtttcctt gattttggat
      481 atacttctta atcacatcaa ttggtgcgcc accagttgtc agaagacaaa aacttttaga
      541 ccagaacatt tctttccaaa gaaattgttt gactcttgga aagtcacgtt ttatcaatct
      601 tgagctggca cttttatagg cattgatgaa ttttgtcaat tctgttttag gttgagcttt
      661 gaacataata tgaacgtggt ctttatcatg attccactcc actaaagtaa tgtgatacga
      721 ttctgaaatt ctttcaaaag tagttttggc ataatcagat atttcatcat caatcacttg
      781 tctacgatat ttcgttacta aaacaaggtg gtaataaaga agaaatactg aatgattatt
      841 tgtatctaat tccatgttat at
//
LOCUS       DAIGSZ010000178          846 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.185, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000178 DAIGSZ010000000
VERSION     DAIGSZ010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..846
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.185"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..300)
                     /locus_tag="NOB31_002941"
     CDS             complement(<1..300)
                     /locus_tag="NOB31_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016438386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma-70"
                     /protein_id="HCI0975084.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRY"
     gene            complement(527..>846)
                     /locus_tag="NOB31_002942"
     CDS             complement(527..>846)
                     /locus_tag="NOB31_002942"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975085.1"
                     /translation="LFLELPAIVSYWVVTVMCFVAMGVSTMFVVQIYTLVQTQTPPQL
                     VGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVASIASIMISIYSKRIFQK
                     LEI"
BASE COUNT          294 a          167 c          115 g          270 t
ORIGIN      
        1 ataacgtaat aaaatcgcac tacgctgttt ttctgacagt ctatgtaaaa ctgtaccaag
       61 tgtttcatca gatacataaa ttgtaaagtg caagacttta aatgatacac aatcataaaa
      121 acaggtatca atcgttccac gttcaacttg tttcgtttcg gctatttcac aaaacaatac
      181 ttcacgttta gaatgtcttg caagctgtct gtttcgactt ttcactttgt tcttaatgac
      241 aatcagcatt aaagaattga actgtaatct gacgatatgc tcgaaagaag atgtcctcat
      301 aatctcaccc cctttctgct aatgctgaaa tatataaacg gaataccgtt tatacccttt
      361 agaaatacag aaaaatggta agaaaaaagc ccacacaaaa catatatttg tgcgagcctt
      421 aaatactgca atattactct ttcttttata acactatcct tttagcagat ttcaaatttt
      481 cttttatata ttgtttttag cctaacatac tatttaaccc cttgtattat atctctaact
      541 tttgaaaaat tctttttgaa tatattgaaa tcatgattga agcaatagaa gctacaaaca
      601 taacaaccca tgtttcttgt ataaatacat cgaataaaat accgtaaacc atttgtccaa
      661 taggttgacc gcacatagca actgctacca gcgtagccat tatctttcct actaattgcg
      721 gtggtgtttg tgtctgaaca agagtgtaaa tttgaacaac aaacatagta gatacaccca
      781 tagccacaaa gcacatcact gtaactaccc agtaggaaac tattgcaggc aattctaaaa
      841 atagcg
//
LOCUS       DAIGSZ010000179          802 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.186, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000179 DAIGSZ010000000
VERSION     DAIGSZ010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.186"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..693
                     /locus_tag="NOB31_002943"
     CDS             <1..693
                     /locus_tag="NOB31_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0975086.1"
                     /translation="ATISRHSSGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILS
                     DGQKIDNNKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEK
                     VMNQRTDFLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYK
                     ADWYGRKIIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINIL
                     TEGLRLHSMGLA"
BASE COUNT          295 a          125 c          148 g          234 t
ORIGIN      
        1 gctacaatat cacgtcattc tagcggtaaa tactatattt ctttgttgtg taaagaagaa
       61 attatcgaat tacctaaaac taattccaca attggtattg acttaggtat tatggacttt
      121 gcgattcttt ctgatggaca aaaaattgat aataataaat tcacgtccaa aatggaaaag
      181 aaactaaagc gtgaacaacg caaattgtct aggcgtgctt tattggctaa aaataaaggt
      241 accaatctat ttgaagctaa aaattatcaa aaacaaaaac gcaaagtagc tagattgcat
      301 gaaaaagtaa tgaatcaacg tactgatttt ctgaataagt tgagtacaga aatgatcaaa
      361 aatcacgata ttatctgtat tgaagactta aacacaaaag gtatgttgcg aaatcataaa
      421 ttagctaaaa gtatttctga tgtttcttgg tcaaagtttg tgactaaatt acaatacaag
      481 gctgactggt atggacgaaa aatcatcaaa gtagataaat ggtttccgtc tagtcagatt
      541 tgttcagagt gcggacataa agatggcaag aaatctcttg aaattcgaga atggacttgt
      601 cctgtttgtc atactcatca tgatcgtgat atcaatgcta gtatcaatat tctgaccgaa
      661 ggtctaagac tacattctat gggattggct tagatccaat catcaagaac cgtaggaact
      721 acggggatag cttggtaaat aagagacacc gctgttagta aagaaatacg ctatcaagta
      781 tgctctattc ccaagaagct cc
//
LOCUS       DAIGSZ010000180          783 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.187, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000180 DAIGSZ010000000
VERSION     DAIGSZ010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.187"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            24..716
                     /locus_tag="NOB31_002944"
     CDS             24..716
                     /locus_tag="NOB31_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HCI0975087.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT          281 a          151 c          159 g          192 t
ORIGIN      
        1 tgaaaaaaag gattttagta acaattggtc tagctttttt gttagctggt tgtaccaacg
       61 ggaatgaatc gaaaaaagaa tcaacaaaag aaacagcgaa agcaacagtt gcaactacta
      121 caacaactag cacagagagc aagtcaactg cagcaagtac agaaacagca gatacctcta
      181 cttcgtcaga gtcttccaaa acgactgaaa caactcaaac atctacttca agttcttctg
      241 tagaggcttc atcttcctct tcagaaagca gcgaacaagt tgaacaaaca ctgtggaatg
      301 cagacaaatc cgcacaatta gaggcattta tgaccaaatg gggccaaaca atgggacaac
      361 aatacaaaag ttatacgaat caaatgagtg tggacttata tggtcttaaa gtccctcaag
      421 ctattttgaa cggggagtgg aagatggcta ttggtggagt gcctgtttct gcagaatggt
      481 cagaaagtgg gacaggtcaa gcagactatc aaatcacagc cgtctattcc gatgcagaga
      541 cagaaccata tctgaaaaag cacgtctatc tattcgggtt tcagcaaaat cagccaaaag
      601 tattggtgac acaacaaaat caggggaatc ccgataatta tctttacttc aacgagacag
      661 cgaataatga attgaaaaat ggctttaatc aaatcgttta tggacaagca aattaatgag
      721 ataaacaagg ggttgtgaca tgtcttttat cacaacccct tgctcagttt atttgttagt
      781 ctt
//
LOCUS       DAIGSZ010000181          732 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.188, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000181 DAIGSZ010000000
VERSION     DAIGSZ010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.188"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(125..>732)
                     /locus_tag="NOB31_002945"
     CDS             complement(125..>732)
                     /locus_tag="NOB31_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
                     /protein_id="HCI0975088.1"
                     /translation="REVEQLLNAYSSVNDPKTVQTVQALAAEKIRDILDHELPEIDTF
                     LTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVKKLKQPAWNEIDLQE
                     HTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQKTSNVSLFLSTTKA
                     GSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
BASE COUNT          187 a          149 c          126 g          270 t
ORIGIN      
        1 aaggggctgt ccccagactt tagtaggcgt cattagctat ctttcgttag catttaaagg
       61 cgaacaccat cacctattca cttccattaa aagatagcat atttttctgt aaaaaacaat
      121 aaaattatcg ttctttcttt acacgttcag caaattcata gaaaggagcc aatttcgtta
      181 actgttgatt acattggtca ctatcatgac aaatataatt cccctttttc gtatacgtgc
      241 catcagaacc tgctttcgtt gtagaaagaa aaagcgaaac attcgatgtt ttctgacaga
      301 ttgcacagat tcccttattt atcgttggtg ataaagtacc gctaatccct tttaattttt
      361 catcttcgta atagaccatg aattttttct gcgtacctgg atcattccag ccgatgtacg
      421 tatgttcttg caagtcgatt tcattccaag ctggttgttt gagttttttc acttttcgga
      481 ataatttctc gatttgtggt ttgctaggct gcataaacgg ctgaacgatt tgcttcagct
      541 cctccaatgc tctttctgct tgcgcttttg tcagttttac gtctaaaact gtcgttaaaa
      601 atgtatcgat ttctggcagt tcgtgatcta atatgtctcg aatcttttca gctgctagtg
      661 cctgaactgt ttgtaccgtt tttggatcat tgacagatga gtacgcattt aataactgtt
      721 ctacttctct ta
//
LOCUS       DAIGSZ010000182          731 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.189, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000182 DAIGSZ010000000
VERSION     DAIGSZ010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.189"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="NOB31_002946"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="NOB31_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HCI0975089.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(481..675)
                     /locus_tag="NOB31_002947"
     CDS             complement(481..675)
                     /locus_tag="NOB31_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975090.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          220 a          156 c          122 g          233 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
      541 gttatagatc aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc
      601 cgcgggttta cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaatctc
      661 atttaattta tacatagaaa acctccagac ttcttgatag ctcaagtata tcttgaggtg
      721 catttgttag t
//
LOCUS       DAIGSZ010000183          670 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.190, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000183 DAIGSZ010000000
VERSION     DAIGSZ010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.190"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>670
                     /locus_tag="NOB31_002948"
     CDS             <1..>670
                     /locus_tag="NOB31_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0975091.1"
                     /translation="LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYL
                     ERYFSRFSLATREAVQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHR
                     VKETTVRLKGNSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIAD
                     RLLAACPNLRQGYQLYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLP
                     QIQNA"
BASE COUNT          204 a          128 c          139 g          199 t
ORIGIN      
        1 ctttgccaaa ggtcttatgc tttgatgaat tcaaatcggt tcgaagtgtt gccagtgcaa
       61 tgagttttat catgatggac ggacaaagcc atgcattatt ggatattgtc gaaaatcgac
      121 gcttgcctta tttagaacgc tatttttctc ggttttcatt agcgactcgt gaagccgttc
      181 aattgattgt tattgatatg tatgcgcctt atgtttcgtt ggtgaaaaag cttttcccga
      241 atgctcagtt gatcatcgat cgtttccaca tcgtccaaca tattggcaga actttcttga
      301 atcatcgagt gaaagaaacc acggtacgac ttaaaggaaa ttcccactct caacgagggt
      361 tagggaaaaa attgaagcgc tattggaaac tcctacaaaa agaagaagca aagttaaact
      421 atgaaaaacg ggtttggcgt gccagtttta aagattattt gactgaaagt gagattgccg
      481 atcgactgtt agctgcttgt cccaacttac gccaaggcta tcagttatac caagacattc
      541 tttatgcggt aaagaaaaga gatcagtcac tatttgagga ttgtttaact agagacatta
      601 gcggtctgcc agaaacctat acaaccactt tacgaacgtt taaaaagttt ctgccacaga
      661 tccaaaatgc
//
LOCUS       DAIGSZ010000184          652 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.191, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000184 DAIGSZ010000000
VERSION     DAIGSZ010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.191"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            145..576
                     /locus_tag="NOB31_002949"
     CDS             145..576
                     /locus_tag="NOB31_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975092.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            578..>652
                     /locus_tag="NOB31_002950"
     CDS             578..>652
                     /locus_tag="NOB31_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HCI0975093.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFV"
BASE COUNT          252 a           95 c          132 g          173 t
ORIGIN      
        1 tggttgggtc aatagaccgt tctactttga acagtgctca actatctatt ggcgcagacg
       61 gagccattaa atggagaaga aattcaagtt atggatcagc ttattcattt gttatcactt
      121 attcaattta agggaggaaa tctaatgaaa gtagtttaca aatcaatcaa gccttacgga
      181 ttcgagcaaa tcattttgaa caatcaagaa aatatccctg aaaactgtac agagattaaa
      241 ccaccagttc ctaactggag accaagattt gattttgata aaaaacagtg ggttgagtta
      301 gctactgaag aagagaaaaa agggaatgct gttgatagcg tagatgaatt ggctaatatt
      361 aaggcattat acgaaacgct gaaggcagaa aatgatgaat tgaaacagct aaattctaaa
      421 gcaatgctaa acaatgtagc aatcaagcaa gaaaatgtct tattgaaaga aaagtcagaa
      481 agtttagcgc agttgaattc aaaaacgatg cttgcttctg tacaaaatac caaggaaatc
      541 gaagaaatca aaaaacaatt acaaggtggg aagtaacatg tattcatatg aagatatcaa
      601 actaatgtat gactggggct gtttcactaa cgaacaagta atggttttcg tt
//
LOCUS       DAIGSZ010000185          639 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.192, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000185 DAIGSZ010000000
VERSION     DAIGSZ010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.192"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..>639)
                     /locus_tag="NOB31_002951"
     rRNA            complement(<1..>639)
                     /locus_tag="NOB31_002951"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          128 a          211 c          134 g          166 t
ORIGIN      
        1 cctccaacac ttagcactca tcgtttacgg cgtggactac cagggtatct aatcctgttt
       61 gctccccacg ctttcgagcc tcagcgtcag ttacagacca gagagccgcc ttcgccactg
      121 gtgttcctcc atatatctac gcatttcacc gctacacatg gaattccact ctcctcttct
      181 gcactcaagt ctcccagttt ccaatgaccc tccccggttg agccgggggc tttcacatca
      241 gacttaagaa accgcctgcg ctcgctttac gcccaataaa tccggacaac gcttgccacc
      301 tacgtattac cgcggctgct ggcacgtagt tagccgtggc tttctggtta gataccgtca
      361 agggatgaac agttactctc atccttgttc ttctctaaca acagagtttt acgatccgaa
      421 aaccttcttc actcacgcgg cgttgctcgg tcagactttc gtccattgcc gaagattccc
      481 tactgctgcc tcccgtagga gtttgggccg tgtctcagtc ccaatgtggc cgatcaccct
      541 ctcaggtcgg ctatgcatcg tggccttggt gagccgttac ctcaccaact agctaatgca
      601 ccgcgggtcc atccatcagc gacacccgaa agcgccttt
//
LOCUS       DAIGSZ010000186          638 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.193, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000186 DAIGSZ010000000
VERSION     DAIGSZ010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.193"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>638
                     /locus_tag="NOB31_002952"
     CDS             <1..>638
                     /locus_tag="NOB31_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HCI0975094.1"
                     /translation="LYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRY
                     ALKISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNA
                     WVPWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLV
                     VPITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLG"
BASE COUNT          202 a           79 c          122 g          235 t
ORIGIN      
        1 cattatattt tgatgataaa tatgttggca gagtagtcgg cggaacactg tcatttgtgt
       61 tgataggttt agtaatttat ttaagaataa tgataaaggg tgctcatttt tttgataaaa
      121 aacagtggag atacgcttta aaaatctctt tgccgctaat cccacattcc ttagcaaata
      181 tagttttagc acaattcgat agaattatga ttaattctta tttaggtcct gctgcggggg
      241 gaatatattc ctacattagt aacataggta ttattctaag cgtaatatgg atgtctacta
      301 ataacgcctg ggttccatgg ttctatggtg agatgagtaa aaataatgaa aaaaaagtga
      361 agaaagttag taactattat ttagtagtct ttactttgat tacgatgatt gtaatggtag
      421 tttcgattga tttagcaaaa tttatggctc cgaaagacta ttattctggg ttatctttag
      481 tggttccgat aaccttaggc tatttctttc agtttttata tagtttacca gttaatgctg
      541 aattttatga gaaaaaaaca tcgtttattg cgattggtac agtagcaagt gctatagtta
      601 atatactatt aaacatgatt ttcataccta ggttagga
//
LOCUS       DAIGSZ010000187          583 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.194, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000187 DAIGSZ010000000
VERSION     DAIGSZ010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.194"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            87..>583
                     /locus_tag="NOB31_002953"
     CDS             87..>583
                     /locus_tag="NOB31_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HCI0975095.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          221 a          106 c           94 g          162 t
ORIGIN      
        1 taaatgaaaa aatccataca aaaaaggaag tcccttctgt agaataaagt taacgacaac
       61 caattcacag aaaagaggac ttccctatga atgattttac tacagaaatt gtgcaaactc
      121 tagtcactaa aggcgattta aatgaattat tccgttcgca cttagaaaaa gcgataaaca
      181 cactcctacg gactgaatta acggcttttt tagattacga aaaatatgat cgcactggtt
      241 ttaattcagg taattcgaga aacggttctt actttcgatc aatcaaaacc gaatatggtg
      301 aattaacatt ggaaatacct agagatcgta atggtgagtt taaacaacaa actttaccag
      361 cctacaaaag aacaaacgat acattggaaa ccactattat ccatttattc gaaaaaggtg
      421 ttacgatgtc tgaaattgct gatttgatcg aaaaaatgta cggtcatcac tatactccac
      481 aaaccatgtc caacatgact aaagttctga ctgaagaagt aaatgccttt aaatccagag
      541 ccttaaatga taagtatgtc gctattttta tggacgctac tta
//
LOCUS       DAIGSZ010000188          583 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.195, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000188 DAIGSZ010000000
VERSION     DAIGSZ010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..583
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.195"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
BASE COUNT          210 a          103 c           95 g          175 t
ORIGIN      
        1 tttaaataga aagacatttg ggttaaattg tgagataata ataaagaaga gtttaaagcg
       61 caccccaaac cacttcccca taagtgtgtt acgctttaaa ctcttttata tttgaagcca
      121 ttaaaaagca taccatattt ttgaaaaaaa gtgagaaaaa aggcttacaa ttggagtggt
      181 agttaattag tgacttattt ttgattttat agcactgata ctataaaata tagatatcat
      241 catattacac aatcttaata ctaacttaaa aaatatctcc tttcacaagt atggtgataa
      301 aattcgttcc gggctacctt tttaggtagc ctactttaat ctttatacct ttctggatca
      361 acgaaagtat actttatata gtcataacgc cgatgatcgc tacgtgcgtc cggcacgtca
      421 gtcatgaatc ggctacacta gactagacag aaaaaataag gtgtgtagaa taataaaaaa
      481 cacactggag gatttttcat gtcaagacgt caacgaagaa cctattcaaa agaattcaaa
      541 caacaaatcg tcgatctcta tctcgctggt aagcctcgcg cag
//
LOCUS       DAIGSZ010000189          575 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.196, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000189 DAIGSZ010000000
VERSION     DAIGSZ010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.196"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>575
                     /locus_tag="NOB31_002954"
     rRNA            <1..>575
                     /locus_tag="NOB31_002954"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          183 a          114 c          166 g          112 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatct
//
LOCUS       DAIGSZ010000190          528 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.197, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000190 DAIGSZ010000000
VERSION     DAIGSZ010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.197"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(5..90)
                     /locus_tag="NOB31_002955"
     tRNA            complement(5..90)
                     /locus_tag="NOB31_002955"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="NOB31_002956"
     tRNA            complement(107..178)
                     /locus_tag="NOB31_002956"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="NOB31_002957"
     tRNA            complement(190..262)
                     /locus_tag="NOB31_002957"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="NOB31_002958"
     tRNA            complement(280..361)
                     /locus_tag="NOB31_002958"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="NOB31_002959"
     tRNA            complement(369..441)
                     /locus_tag="NOB31_002959"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="NOB31_002960"
     tRNA            complement(445..517)
                     /locus_tag="NOB31_002960"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAIGSZ010000191          516 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.198, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000191 DAIGSZ010000000
VERSION     DAIGSZ010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.198"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(107..>516)
                     /locus_tag="NOB31_002961"
     CDS             complement(107..>516)
                     /locus_tag="NOB31_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HCI0975096.1"
                     /translation="GTPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMN
                     AASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYED
                     SQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          163 a          103 c           78 g          172 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttccat
//
LOCUS       DAIGSZ010000192          510 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.199, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000192 DAIGSZ010000000
VERSION     DAIGSZ010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.199"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(34..234)
                     /locus_tag="NOB31_002962"
     CDS             complement(34..234)
                     /locus_tag="NOB31_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCI0975097.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          169 a           79 c           92 g          170 t
ORIGIN      
        1 aaataacccc tgtatccttt gcggtacagg gggttatttt gtataagtag acattgtagt
       61 ttctaaactg ctatgtccta aacgtttcga tacgctaagt atatttactc cttgataaag
      121 taaaatagat gcatgcgtat gtcttagtcc atcaataaac agtcgaagag aaaataggga
      181 aaaattgatt actaaagaaa aacttactag gtcgacggtg tagttgattt tcatacttca
      241 atagattcga attaaacgat ttcgattggc ttataccagt cctatccaac gaaagatata
      301 tcgttcttaa ctctagcggt ataacttgaa gctttacgta aagccaatgg gaatgaactg
      361 gagatgactt tttattattt ttagtaatag ctgatgggtt aatacttaca actttccttt
      421 tcaaagtacc atataaaaaa acggtggggt tgtttagcga aataaaggat ctaagccaat
      481 agcttagatc ctttattcta tgctttatat
//
LOCUS       DAIGSZ010000193          506 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.200, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000193 DAIGSZ010000000
VERSION     DAIGSZ010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.200"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>506
                     /locus_tag="NOB31_002963"
     CDS             <1..>506
                     /locus_tag="NOB31_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0975098.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFS"
BASE COUNT          167 a           89 c          103 g          147 t
ORIGIN      
        1 caaatcaaac tgtggtagac gtccgcttgt tttacccgag gaacaatcag aatatattca
       61 aagaaaggtt gttcaaggat ggacacccga tgtgattgtt ggtcgtgcag cgtttcctat
      121 tagttgttct gctcgtacca tttatcgtat gttcaaaaag gggctatttg attcttctga
      181 cttaccgatg aaaggcaagc gtaaaccgaa tggacatcaa gaaagacgtg gaaaacaaac
      241 tttccgccgc tctattcatg aacgtgaaaa ggattatagc caattctcaa atgagtttgg
      301 tcaccttgaa ggtgacacta tcgtaggtct gaaacataaa agtgctgtaa ttaccttagt
      361 tgaacgatta tcaaaagtta tcatcacatt gaaaccgtgt ggtagacaag cgattgatat
      421 tgaaaaaaaa ttaaatcaat ggtttgaatc tgtaccgaaa aacctattca aatccatcac
      481 ttttgattgt ggaaaggaat tttcaa
//
LOCUS       DAIGSZ010000194          504 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.201, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000194 DAIGSZ010000000
VERSION     DAIGSZ010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.201"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
BASE COUNT          226 a           70 c           81 g          127 t
ORIGIN      
        1 ccttaggcag cttttgctgt gtagaaagga ataaataata acgaaagttc aaaagctaat
       61 gccgactatt ctagacatta aagaagacga aaacgaacga taaagaaaga aaagttatga
      121 ataatcgttt attgaaaaaa acttgaaaaa atacaaaaaa ttcgttgacc aagctaaatt
      181 tagttggtat attattactt gtccaaaaga cagaagaaaa tatttattca aaaacataac
      241 aaaaaagtta ttgacatgtt actaacgaca tgataagata actgagtcgt taaaaaagaa
      301 ccacttgcga agcttgattc tatcgaaaaa aacttcaaaa aagttcttga caaataacaa
      361 acgataagtt atgataaatg agttgccgaa agatttcgaa aaacgaaatc gaaaaaaact
      421 tttaaaaaag agttgacaat cgcttgtctc tctgatatga tataaaagtt gctacggcag
      481 ccaaaaatga atcgggaaac actc
//
LOCUS       DAIGSZ010000195          501 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.202, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000195 DAIGSZ010000000
VERSION     DAIGSZ010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.202"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>501
                     /locus_tag="NOB31_002964"
     CDS             <1..>501
                     /locus_tag="NOB31_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HCI0975099.1"
                     /translation="QEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDA
                     DGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQG
                     TEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFG
                     FSVCTE"
BASE COUNT          184 a           90 c           97 g          130 t
ORIGIN      
        1 tgcaagaata tggcaaacta ctctatcaaa tttggaaaaa gaaaaataaa aaatcctttt
       61 attcatggaa aatggatgaa acgtacatca aaattaaagg aaaatggcat tatttgtatc
      121 gagccatcga tgcagatggt ttaaccttgg atatttggtt acgtaaaaaa cgggacacac
      181 aagcagccta tgcttttctt aagcggttag tgaagcagtt tgatgaaccg aaggttgtag
      241 tcacagataa agccccctct attacaagtg cctttaagaa actaaaagaa tacggctttt
      301 atcaagggac agaacatcgt accattaaat acctgaataa tttgattgaa caagaccatc
      361 gtccagtaaa gagacgcaat aaattctatc gaagtttacg cactgcctct accacgatta
      421 aaggcatgga agccattcga ggattatata agaaaacccg aaaagaaggc actctcttcg
      481 ggttttcggt ctgtactgaa a
//
LOCUS       DAIGSZ010000196          491 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.203, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000196 DAIGSZ010000000
VERSION     DAIGSZ010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.203"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>491
                     /locus_tag="NOB31_002965"
     CDS             <1..>491
                     /locus_tag="NOB31_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCI0975100.1"
                     /translation="FPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSP
                     LCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVK
                     VLETLSEEANLPNILGDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQ
                     RKT"
BASE COUNT          179 a           96 c           80 g          136 t
ORIGIN      
        1 ctttcctagt aggagtcgat tcactcgctt aagttcaaac ttagcttaca ctatcaagat
       61 tattcgatac tttttcatca agaagctcac caaaggtgaa ctagtcggaa ttatagatag
      121 ttttcctagt ccattatgta aaccagttag aaatagacaa gcaaaactat tgaatcaaat
      181 agccaaagtt ggctataact caacaaaaaa atcttatttt tatggtctta aaattcatat
      241 gatcgttact aagactggct ttccgattac ttactcaatc acgaatccag gtgtccatga
      301 cgtgaaagtg ttagagactt tatcggaaga agcgaatctt cccaatatcc taggggacaa
      361 aggatatatt agccataaaa tccatgaaaa gcttgccctt aagggcatta ctatatccgt
      421 tccgccacgt aaaaacatgg ataaatcaga aaaactagac cacagcttac ttggaaaaca
      481 aagaaaaaca g
//
LOCUS       DAIGSZ010000197          470 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.204, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000197 DAIGSZ010000000
VERSION     DAIGSZ010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.204"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>470
                     /locus_tag="NOB31_002966"
     CDS             <1..>470
                     /locus_tag="NOB31_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HCI0975101.1"
                     /translation="ALSKRGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKT
                     TNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLV
                     KKAFSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAV"
BASE COUNT          167 a           78 c           88 g          137 t
ORIGIN      
        1 aagccttatc aaaacgaggc attcagatca gccgacgaaa aattagtaga atcatgaaaa
       61 atagaggatt aaaatcgagc tatactgttg cttattttaa agtacatcat tctacttgca
      121 atgaagccaa aacgacaaac gtattgaatc gtaaattctt aagagacaac ccattagaag
      181 cgatcgtaac agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca
      241 ttttggatct gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg
      301 ttctagtaaa aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc
      361 atactgatcg tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg
      421 acatcaatcg atcattgagt cataaaggct gtccttttga taatgccgta
//
LOCUS       DAIGSZ010000198          460 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.205, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000198 DAIGSZ010000000
VERSION     DAIGSZ010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.205"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(20..91)
                     /locus_tag="NOB31_002967"
     tRNA            complement(20..91)
                     /locus_tag="NOB31_002967"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="NOB31_002968"
     tRNA            complement(113..200)
                     /locus_tag="NOB31_002968"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="NOB31_002969"
     tRNA            complement(225..298)
                     /locus_tag="NOB31_002969"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="NOB31_002970"
     tRNA            complement(312..382)
                     /locus_tag="NOB31_002970"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="NOB31_002971"
     tRNA            complement(384..459)
                     /locus_tag="NOB31_002971"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DAIGSZ010000199          440 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.206, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000199 DAIGSZ010000000
VERSION     DAIGSZ010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.206"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            11..>440
                     /locus_tag="NOB31_002972"
     CDS             11..>440
                     /locus_tag="NOB31_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI0975102.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          168 a           57 c           88 g          127 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag
//
LOCUS       DAIGSZ010000200          421 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.207, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000200 DAIGSZ010000000
VERSION     DAIGSZ010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.207"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..390
                     /locus_tag="NOB31_002973"
     CDS             <1..390
                     /locus_tag="NOB31_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0975103.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          163 a           74 c           65 g          119 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc
      361 gatacattag tttcaatgtt tactgagtaa ctaattattt tgcaggagga caatttattt
      421 a
//
LOCUS       DAIGSZ010000201          401 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.208, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000201 DAIGSZ010000000
VERSION     DAIGSZ010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.208"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(41..114)
                     /locus_tag="NOB31_002974"
     tRNA            complement(41..114)
                     /locus_tag="NOB31_002974"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(78..80),aa:Ile,seq:cat)
     gene            complement(128..201)
                     /locus_tag="NOB31_002975"
     tRNA            complement(128..201)
                     /locus_tag="NOB31_002975"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(165..167),aa:Met,seq:cat)
     gene            complement(229..301)
                     /locus_tag="NOB31_002976"
     tRNA            complement(229..301)
                     /locus_tag="NOB31_002976"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(266..268),aa:Ala,seq:tgc)
     gene            complement(321..394)
                     /locus_tag="NOB31_002977"
     tRNA            complement(321..394)
                     /locus_tag="NOB31_002977"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(358..360),aa:Pro,seq:tgg)
BASE COUNT          108 a          113 c           94 g           86 t
ORIGIN      
        1 gacttgggta atcctccata tgaaacttac aacgccacaa tggaccttgt aggactcgaa
       61 cctacgaccg gacggttatg agccgtctgc tctaaccaac tgagctaaag gtccaggctc
      121 ttaaaaatcg cggcggaggg gatcgaaccc ccgacctccc gggtatgaac cggacgctct
      181 agccagctga gctacaccgc gaaaaagata ttcattattt aaatgaaatg gagcctagcg
      241 ggatcgaacc gctgacctcc tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc
      301 cgtgtttaaa tttataatta tcgggaagac aggattcgaa cctgcgaccc cttggtccca
      361 aaccaagtgc tctaccaagc tgagctactt cccgtttaat t
//
LOCUS       DAIGSZ010000202          367 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.209, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000202 DAIGSZ010000000
VERSION     DAIGSZ010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.209"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>367
                     /locus_tag="NOB31_002978"
     CDS             <1..>367
                     /locus_tag="NOB31_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0975104.1"
                     /translation="KIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNL
                     YLDSTHIKANANKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKL
                     KERKISKADPESGYYVKGER"
BASE COUNT          137 a           61 c           80 g           89 t
ORIGIN      
        1 aaaatccccc atttctcaac ttttggaaag aattatgttc gccgatttag agaaacgacg
       61 gtgtttgagg atatttttgc ctatatttta gaacaagcag ttaaagcagg ttttgtaaca
      121 gaggataatt tgtatctgga ttctacccac atcaaagcta acgccaataa acataagttt
      181 acgaaagaaa tgacccatga tgaagcgaaa gcctatcagg atgaattaga agatgagatc
      241 aatcgtcaac gaatagaggc tggaaaacgc ccttttactt tggacttaga aaaggaagtg
      301 aagctgaaag aaagaaaaat aagtaaagct gatccggaaa gcggctacta cgtcaaaggc
      361 gaacgag
//
LOCUS       DAIGSZ010000203          353 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.210, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000203 DAIGSZ010000000
VERSION     DAIGSZ010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..353
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.210"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..>353)
                     /locus_tag="NOB31_002979"
     rRNA            complement(<1..>353)
                     /locus_tag="NOB31_002979"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           79 a          104 c           85 g           85 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc agg
//
LOCUS       DAIGSZ010000204          349 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.211, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000204 DAIGSZ010000000
VERSION     DAIGSZ010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.211"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(44..>349)
                     /locus_tag="NOB31_002980"
     CDS             complement(44..>349)
                     /locus_tag="NOB31_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0975105.1"
                     /translation="TIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQF
                     ETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT           98 a           86 c           64 g          101 t
ORIGIN      
        1 atcctcggat ctgattttct ccggcagaag cacaatcatt caattacgct gcctctccag
       61 aggtatcaga tccgcgctca ttatcaagga ttcgcttcgc caatctctgt tgtcgaattt
      121 ggatcggtgt ttcatacgcc aacgtgccat gtaagcgtag atagttccac caatgcacat
      181 aatcaaacaa ttctagacgt agctgtgcca gtgtctcaaa ttggtattga tgcacgaatt
      241 ctactttgac agatttatag gttgattcca caacggcatt atcatacgga caacccttcc
      301 tactcaatga acgagtaatt ccaaaaccat tcagaatctc atgaatggt
//
LOCUS       DAIGSZ010000205          325 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.212, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000205 DAIGSZ010000000
VERSION     DAIGSZ010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..325
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.212"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>325
                     /locus_tag="NOB31_002981"
     rRNA            <1..>325
                     /locus_tag="NOB31_002981"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           98 a           63 c           94 g           70 t
ORIGIN      
        1 cgaacccacg tacgttgaaa agtgcgggga tgaggtgtgg gtagcggaga aattccaaac
       61 gaacttggag atagctggtt ctctccgaaa tagctttagg gctagcctcg gaattgagaa
      121 tgatggaggt agagcactgt ttggactagg ggcccatctc gggttaccga attcagataa
      181 actccgaatg ccattcattc atatccggga gtcagactgt gagtgataag atccatagtc
      241 gaaagggaaa cagcccagac caccagctaa ggtcccaaaa tatatgttaa gtggaaaagg
      301 atgtggggtt gcacagacaa ctagg
//
LOCUS       DAIGSZ010000206          321 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.213, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000206 DAIGSZ010000000
VERSION     DAIGSZ010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.213"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(69..321)
                     /locus_tag="NOB31_002982"
                     /pseudo
     CDS             complement(69..321)
                     /locus_tag="NOB31_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DAIGSZ010000207          297 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.214, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000207 DAIGSZ010000000
VERSION     DAIGSZ010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.214"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
BASE COUNT          105 a           33 c           46 g          113 t
ORIGIN      
        1 gactacctgt attagtcctc ttttttgacc agattttgac cagtctattt tacattctaa
       61 tatattcata tgagctaatt ttatgattaa atggtaagtt tttccttgtt tgttttagtt
      121 taaactagtg tgtaattcaa aaatctatat ggaaggatct gtggggtaaa tcattataca
      181 aaagtaaaat tttacttatt aacaggctgt agaaatataa aaaagaacta aaatttaact
      241 aaattatgtg ctattcttaa ggaaagccaa gtgtatgaga aagtttctga gaatata
//
LOCUS       DAIGSZ010000208          296 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.215, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000208 DAIGSZ010000000
VERSION     DAIGSZ010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.215"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
BASE COUNT          105 a           52 c           43 g           96 t
ORIGIN      
        1 ctctataatt tctaggactg atggaaattt tctatctgtc ctagtttttt tgtaaaaaaa
       61 caaaaagaca tacaaaattt ccggtagaat agagtctcct acaacatcat tctgggggaa
      121 ttcttgtatg tccatgaatc attttatcaa acaactcttt actattaaag actcaaatat
      181 ccaaattcaa tcctttgaag aaacttttta taaaagcaga aaaagtatcg ttattgaggg
      241 aactctgatc cgtacctaca gacgttgtcc gtgttgtaaa gattctacaa agcaaa
//
LOCUS       DAIGSZ010000209          290 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.216, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000209 DAIGSZ010000000
VERSION     DAIGSZ010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.216"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            42..>290
                     /locus_tag="NOB31_002983"
     CDS             42..>290
                     /locus_tag="NOB31_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0975106.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLE"
BASE COUNT           88 a           53 c           57 g           92 t
ORIGIN      
        1 tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat actcagctta
       61 tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta
      121 aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag
      181 aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa
      241 ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag
//
LOCUS       DAIGSZ010000210          281 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.217, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000210 DAIGSZ010000000
VERSION     DAIGSZ010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.217"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            28..>281
                     /locus_tag="NOB31_002984"
     CDS             28..>281
                     /locus_tag="NOB31_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0975107.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDT"
BASE COUNT           84 a           53 c           56 g           88 t
ORIGIN      
        1 tgaaaacgaa tgcaaggagt gatagctatg atgtctaaaa acaatacgaa tggtagaaat
       61 caatttgcga tgcttacgat tgatgatcta gttcctcaag atcatctcgt tcgaaagatt
      121 gatgccgcgc ttgattttga atttatttat ccaatcgtcg aagccactta ctccgattta
      181 ggtcgcccaa gtatcgatcc agtgattctg atcaaattgg tgtttattca gtatttattc
      241 ggtatccgtt ccatgcgaca aaccattaag gaagtcgata c
//
LOCUS       DAIGSZ010000211          266 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.218, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000211 DAIGSZ010000000
VERSION     DAIGSZ010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.218"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(34..>266)
                     /locus_tag="NOB31_002985"
     CDS             complement(34..>266)
                     /locus_tag="NOB31_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0975108.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           78 a           39 c           47 g          102 t
ORIGIN      
        1 agaaggactg accttctgtc tcagattttt ttgttatttc acttgaatca attgattgat
       61 caaaaaaatc ctgattttca tgttctcaaa tgatttaaat ccataagata atcgtttcag
      121 tgtcttgata tggggaatct tggcctctat tttgccatta gaatacgggt aaatcatagc
      181 attgtaaata ccttcttcat acgttaaaag gttttgaagt ttcgtgcgaa gttgtgcatc
      241 aagtgtttca ggaagatttt ttaata
//
LOCUS       DAIGSZ010000212          257 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.219, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000212 DAIGSZ010000000
VERSION     DAIGSZ010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.219"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>257
                     /locus_tag="NOB31_002986"
     CDS             <1..>257
                     /locus_tag="NOB31_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0975109.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPS"
BASE COUNT           85 a           54 c           45 g           73 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc cttccca
//
LOCUS       DAIGSZ010000213          243 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.220, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000213 DAIGSZ010000000
VERSION     DAIGSZ010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.220"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>243
                     /locus_tag="NOB31_002987"
     CDS             <1..>243
                     /locus_tag="NOB31_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975110.1"
                     /translation="SDADKYNPEGQKVTTELNKEPDASEGIKNKEDLPKDTKYTWKEK
                     VDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRS"
BASE COUNT           99 a           33 c           56 g           55 t
ORIGIN      
        1 atctgacgct gacaaatata atcctgaagg tcaaaaagtg actacagaat tgaataagga
       61 accagacgca tctgagggaa ttaagaacaa agaagattta ccaaaagata ctaagtatac
      121 ttggaaagaa aaagtagatg ttagcgcagc tggaaataaa aaagggactg ttgtagtgac
      181 atatccagat ggatcatctg atgaagttga agtagatgtt acagtgacag acaatcgttc
      241 tga
//
LOCUS       DAIGSZ010000214          241 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.221, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000214 DAIGSZ010000000
VERSION     DAIGSZ010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.221"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..220)
                     /locus_tag="NOB31_002988"
     CDS             complement(<1..220)
                     /locus_tag="NOB31_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCI0975111.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFP"
BASE COUNT           63 a           45 c           46 g           87 t
ORIGIN      
        1 caggaaaaat gatttcggtt ctcccacaac gtcgcttatt ttctttgtat tgttcaaagt
       61 attcaagtgc tgttccacca catttgagaa agttatagac attgtaaatt gtttggcgtc
      121 cacgtttaag ctgcttcgca acgatagcaa ccggagtttc ttgatgaaaa tatgcttcta
      181 tcattacaag ctcgtttggt gtaagatggg tataagtcat ttatgttcac tctccttgta
      241 t
//
LOCUS       DAIGSZ010000215          232 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.222, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000215 DAIGSZ010000000
VERSION     DAIGSZ010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.222"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
BASE COUNT           79 a           35 c           45 g           73 t
ORIGIN      
        1 gagaaaaagc atggaatgcg ctgcatcagg tatcgaggct tagaaaaaaa tcaggtgcat
       61 acgatgcttg tttttgccga aatgagtctg aaaaaattgg tcacttagca gtgggagcat
      121 atgtcttcat attttttatt atacaaaaat agacaaaagt atcagtctac actcttagta
      181 aagaggaaac tgatactttt gtctacagta tgatatttct tacatctact tt
//
LOCUS       DAIGSZ010000216          222 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.223, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000216 DAIGSZ010000000
VERSION     DAIGSZ010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.223"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>222
                     /locus_tag="NOB31_002989"
     CDS             <1..>222
                     /locus_tag="NOB31_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCI0975112.1"
                     /translation="RKAYGTRKLKKCLAKRGLQLSRRRIGRIMKRRGLTSTYTIAHFK
                     GQRTACNEAKTANVLDRTFTQEQPLEAIVT"
BASE COUNT           71 a           50 c           54 g           47 t
ORIGIN      
        1 cgaaaggctt acggtacccg aaaattgaag aagtgtttag caaagcgtgg gcttcaactc
       61 agtcggcgcc gaatcggtcg aatcatgaaa cgccgcggat tgacatctac ctatacgatc
      121 gctcatttta aagggcaacg aacagcttgt aatgaagcga aaacagcgaa tgtattagat
      181 cggaccttta cacaagaaca gccattggaa gccatcgtta cg
//
LOCUS       DAIGSZ010000217          214 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.224, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000217 DAIGSZ010000000
VERSION     DAIGSZ010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..214
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.224"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            <1..>214
                     /locus_tag="NOB31_002990"
     CDS             <1..>214
                     /locus_tag="NOB31_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0975113.1"
                     /translation="IAKNCQVSLTTVIRTLKEFKSYLPKQSKRILPRVLMVDEFRSHA
                     SIEDKMSFICADGETGQLIDVLPTRK"
BASE COUNT           66 a           38 c           44 g           66 t
ORIGIN      
        1 ttattgcgaa aaattgtcag gtatctttga ccaccgttat tcgtacgttg aaagagttta
       61 aaagctactt accaaagcaa tctaagagga ttctccccag agtattgatg gttgatgaat
      121 ttcgttcgca cgcttccata gaagataaaa tgagctttat ttgcgcagat ggcgaaacag
      181 gacaattaat tgatgtcttg cctacgcgta aatt
//
LOCUS       DAIGSZ010000218          213 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.225, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000218 DAIGSZ010000000
VERSION     DAIGSZ010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.225"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            1..213
                     /locus_tag="NOB31_002991"
                     /pseudo
     CDS             1..213
                     /locus_tag="NOB31_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT           90 a           40 c           40 g           43 t
ORIGIN      
        1 tacgccttct tctttcgata aatggatgaa gcaagcacaa tcaacgggct cattcaaaga
       61 aagagacaac ttaacaccag aacaagcaga attgatcgca ctaagaaaga aaaataagca
      121 actcgaaatg gagaatgata ttttaaagca agcggcgctg atattcggac gaaaagacaa
      181 gtaattgatg ccaacaagca taaatattcc ata
//
LOCUS       DAIGSZ010000219          211 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.226, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000219 DAIGSZ010000000
VERSION     DAIGSZ010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.226"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            55..>211
                     /locus_tag="NOB31_002992"
     CDS             55..>211
                     /locus_tag="NOB31_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0975114.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTSG"
BASE COUNT           84 a           33 c           43 g           51 t
ORIGIN      
        1 gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct
       61 aagagaacac gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta
      121 gctggaaagc cacgtgtaga aatcattcga gaatatgaac taacggcttc agcatttgac
      181 aaatgggtaa agcaatctaa aacgagtggt t
//
LOCUS       DAIGSZ010000220          206 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.227, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000220 DAIGSZ010000000
VERSION     DAIGSZ010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.227"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
BASE COUNT           75 a           33 c           37 g           61 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctcc
//
LOCUS       DAIGSZ010000221          206 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.denovo.228, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000221 DAIGSZ010000000
VERSION     DAIGSZ010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.denovo.228"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..>206)
                     /locus_tag="NOB31_002993"
     CDS             complement(<1..>206)
                     /locus_tag="NOB31_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCI0975115.1"
                     /translation="IAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRGVQEVLL
                     FITDGLKGMKDTIHQIYPKAKYQH"
BASE COUNT           56 a           42 c           37 g           71 t
ORIGIN      
        1 caatgctgat attttgcttt aggataaatt tgatggatag tatctttcat gccttttaag
       61 ccgtccgtaa taaaaagcaa gacttcttga actcctctgg agttaatatc ctgtagcagc
      121 tcattccaaa cgtatgttga ttcagttgga gcaatcgcat aactcagtac ttctttagtg
      181 ccgtcttctc gtataccaat ggcaat
//
LOCUS       DAIGSZ010000222        14453 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.guided.068, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000222 DAIGSZ010000000
VERSION     DAIGSZ010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.guided.068"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(75..1367)
                     /locus_tag="NOB31_002994"
     CDS             complement(75..1367)
                     /locus_tag="NOB31_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCI0975116.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSECRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
     gene            1434..1745
                     /locus_tag="NOB31_002995"
     CDS             1434..1745
                     /locus_tag="NOB31_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0975117.1"
                     /translation="MFWKIKKMLVSSTNIKKYRAKKIKERQAQGIEIAKKKGKFKGRQ
                     HKFKENDPRLKHAFDLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRD
                     S"
     gene            1745..3889
                     /locus_tag="NOB31_002996"
     CDS             1745..3889
                     /locus_tag="NOB31_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HCI0975118.1"
                     /translation="MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDPLFTDETFIT
                     FGFGHLVELAEPGHYDEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAELLKKANT
                     IIVATDSDREGENIAWSIIHKANAFSKDKTFKRLWINSLEKDVIRSGFQNLQPGMNYY
                     PFYQEAQTRQIADWLIGMNASPLYTLNLQQKGVQGTFSLGRVQTPTLYLIFQRQEAIE
                     NFKKEPFFEVEASIKVNQGSFKGVLSPTQRFKTQEELLAFVSSKQAKIGNQEGIIADV
                     QTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYEAKLLSYPRTDTPFITE
                     NEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHHAIIPTKQVPTESALAK
                     MDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKVADLLFQSIGKTPKQEGWKILFKQ
                     QTKEEKEDVQTLPLVIIGERAEVGVKSVEKETQPPKAFTEGTLLTAMKTANKTVDDEE
                     AIKILQEVEGIGTEATRASIIEALKQKEYIQVIKNKLVVTEKGKLLCQAVESQHLLTS
                     AEMTAKWETYLKKIGKREGNQENFITNIKKFIVHLLEAVPNDIEKLNFSDYQEQKEKE
                     AEKSIVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFRKKKLTKTNVKELLEGKET
                     LVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            4009..4248
                     /locus_tag="NOB31_002997"
     CDS             4009..4248
                     /locus_tag="NOB31_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HCI0975119.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            4297..4381
                     /locus_tag="NOB31_002998"
                     /pseudo
     CDS             4297..4381
                     /locus_tag="NOB31_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            4506..5243
                     /gene="erm(B)"
                     /locus_tag="NOB31_002999"
     CDS             4506..5243
                     /gene="erm(B)"
                     /locus_tag="NOB31_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCI0975120.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(5440..8406)
                     /locus_tag="NOB31_003000"
     CDS             complement(5440..8406)
                     /locus_tag="NOB31_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HCI0975121.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            8552..9127
                     /locus_tag="NOB31_003001"
     CDS             8552..9127
                     /locus_tag="NOB31_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCI0975122.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            9341..10036
                     /gene="vanR"
                     /locus_tag="NOB31_003002"
     CDS             9341..10036
                     /gene="vanR"
                     /locus_tag="NOB31_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCI0975123.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            10014..11168
                     /locus_tag="NOB31_003003"
     CDS             10014..11168
                     /locus_tag="NOB31_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HCI0975124.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            11383..12351
                     /locus_tag="NOB31_003004"
     CDS             11383..12351
                     /locus_tag="NOB31_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HCI0975125.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            12344..13375
                     /gene="vanA"
                     /locus_tag="NOB31_003005"
     CDS             12344..13375
                     /gene="vanA"
                     /locus_tag="NOB31_003005"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HCI0975126.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAFITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            13381..13989
                     /locus_tag="NOB31_003006"
     CDS             13381..13989
                     /locus_tag="NOB31_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HCI0975127.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         4720 a         2582 c         2928 g         4223 t
ORIGIN      
        1 ttgtcaaatg atgttggtaa agagaaatct tagaataatt ggagatcaag tggatcagtt
       61 cctcttgatc ttttttagtt gaaaatcaat gcgttgccat gacgaatcat gatgcgcaat
      121 ttgaaattat aaaagctacg aaagccatat gcatttcgtt ttaacacttt gatatggttg
      181 ttcagacatt caagtgggcc atttgaataa ctttgttgta aagcattttt gatttgtggc
      241 agaaatttct ggaacgttct caaggtcgtc tgatagcctt cgggaagcat gatattattg
      301 gtaagtagtt cttcaaacga tacgtagtct cgttccttta cagcgtaaag aaagtcttga
      361 tataactgat agcctacacg caaagcaggg ctccctttca gtaagcgatc cacaatatcg
      421 gtctctgtta aatgagcttt gaagccaggt cgccaaaggc gtcgagtata atcaagcttg
      481 cgttcatctt tttgaagaag tttccagtat ctttttaatt gcttacctaa ttgatagtgt
      541 ttttgttctt tgctttttaa tagttggttc gtttctttga ttcgatgatt gcgaaaggta
      601 cgaccaatat gttggacgat gtgaaaccgg tcaataatca gctgtgcttt tggaaacagc
      661 tttttaacga gcgatacata aggagcgtac atatcaatca cgatccattc gaccgcttca
      721 cgaatttctc gtgaaaaatg actaaaataa cgttttaaaa aaggcagttg tcggttctcg
      781 acaatgtcca acaagcgctg tgtttgtcca tccatcatga tgaaactcat agcacctgaa
      841 acaccccgaa ctgatttgaa ttcatcaaaa caaagtacct taggtaacgg tgtccgaaaa
      901 ggattcaacg gacgataaaa tcgcttcata atacggtaaa cagaagagac cgatagattt
      961 ttctgagcgg cgatctctgt cattgaggta ttttttttca gacgagtcac gacagaccag
     1021 cggactttct cactgatgaa acagtgtttt ttcgcaacag aagtatctgc gacaaaggtc
     1081 cgctgacaag ctttgcattt gaagcgttgc tttttcaatt cgaggtaggt acggcattca
     1141 gaaacatcgt tcattaacaa ccggacggtt gttgtacccc aacgcacaat atctgaagca
     1201 atctggtgtt tacagtggat gcattcttgg gctgtataaa tcaagtttcc acgataaata
     1261 tgacagattt gccctttgta tttttctttt gtgagacaat tttcgttaaa agtaactgat
     1321 aagtctagaa tatctaatgt ttctttgata aggtgagtgt aagacatctt gattcctcct
     1381 tttgggttgg ttcgccaaat taattctaaa ggatttcaag gtgtcttttc tatatgtttt
     1441 ggaaaataaa aaagatgctg gtgtcatcca ccaacatcaa aaagtataga gctaaaaaaa
     1501 ttaaggaacg tcaggcacaa ggaatcgaaa ttgctaagaa aaaaggcaaa ttcaaaggtc
     1561 gtcagcataa atttaaagaa aatgatccac gtttaaagca tgctttcgat ttgtttttga
     1621 atggtttatc cgataaagaa gttgaagaac aaactggaat caatcgccga acgtttagaa
     1681 ggtatcgagc aagatataac gtgacagtcg atcaaagaaa aaacaatgaa aagagggata
     1741 gttaatgagt acggttattt tagctgaaaa accaagccag gcattagcct acgcaagtgc
     1801 tttaaaacaa agcaccaaaa aagacggtta ttttgagatc aaagacccac tatttacaga
     1861 tgaaacgttt atcacctttg gttttgggca tttagtggaa ttagcagaac caggtcatta
     1921 tgacgaaaag tggcaaaatt ggaaacttga atctttgccg atttttcctg atcgatacga
     1981 ttttgaagtt gcaaaagata agggaaagca gtttaaaatt gttgcagaac ttctcaaaaa
     2041 ggcaaataca attattgttg caacagatag cgacagagaa ggtgaaaata tcgcctggtc
     2101 gattatccat aaagcaaatg ccttttcaaa agataaaaca tttaaaagac tatggatcaa
     2161 tagcttagaa aaagatgtaa tccgaagcgg ttttcaaaat ttgcaacctg gaatgaatta
     2221 ctatcccttt tatcaagaag cgcaaacacg ccaaattgcc gattggttga tcggcatgaa
     2281 cgcaagccct ttgtatacgt taaatttaca acagaagggc gtacaaggta cattttcact
     2341 aggacgtgtt caaacgccca ccttatacct tatttttcag cgccaggaag ccatagagaa
     2401 ttttaaaaaa gaaccttttt tcgaggtgga agctagtata aaagtaaacc aagggtcgtt
     2461 taagggcgtt ctaagcccca cacagcgttt taaaacccaa gaggagcttt tagcttttgt
     2521 ttcttctaaa caagctaaaa taggcaatca agaggggata attgctgatg ttcaaaccaa
     2581 agagaagaaa acgaatagtc cgagtttgtt ttctttaagt agtttgcaat caaaagtcaa
     2641 tcagctttat aaagcgacag cgagccaaac tttaaaagct atgcaaggac tgtatgaagc
     2701 aaaattattg agttatccaa gaacagatac accatttatt acagagaacg aatttgctta
     2761 tttaaaagcg aattttggca aatatagcgg ttttttagga cttgatcttg aaatggttca
     2821 aacagagcct agaaagcgtt atgtggacgg tagtaaggta caggaacacc acgccattat
     2881 cccaacaaaa caagtaccta ccgaatctgc attagcgaaa atggacgatt tacaacgaaa
     2941 aatttatgct ttagtcgtta aaacgaccgt tgccatgttt ttacctgatt acttgtatga
     3001 agaaaccaag atacaaacga aagtagctga tttgctgttt caatcgatcg gaaagacacc
     3061 aaagcaagaa gggtggaaaa ttcttttcaa acaacaaacc aaagaagaaa aagaggacgt
     3121 tcaaacgtta ccactcgtta tcattggcga acgtgccgaa gttggtgtta agagtgttga
     3181 aaaagaaacg caaccgccaa aagcttttac agagggtaca ttattaactg ctatgaaaac
     3241 ggcgaataaa acggttgatg atgaagaagc aatcaagatt ttacaagaag ttgaggggat
     3301 tggaacagaa gcgacaagag caagtattat tgaagcgtta aaacaaaaag aatatatcca
     3361 agtgattaag aataagcttg ttgtaactga aaaaggaaaa ttattgtgcc aggcagttga
     3421 aagtcagcac cttttaacga gtgctgaaat gacggctaaa tgggaaacgt atttaaaaaa
     3481 aatcggtaaa agagaaggca atcaagagaa ctttattacg aatatcaaaa aattcattgt
     3541 tcatttactg gaagctgtac ctaacgatat agaaaaacta aatttttctg attaccagga
     3601 acagaaagaa aaagaagcag aaaaaagtat tgtaggaaaa tgtcctaagt gtggcaacaa
     3661 tattgtatta aaaaaatcgt tttatggttg ttcaaattat cctgaatgta agtttacttt
     3721 agctgaacat tttagaaaga aaaaactaac caaaacgaat gtaaaagaat tactggaggg
     3781 aaaagaaacc ctggtaaaag gaatcaaaaa caaagagaaa aagccctaca atgccgttgt
     3841 aaaaattggg gaaaagggat atattgattt tatatctttc tcaaaataaa cataaaagcc
     3901 ctttaaagag ggcttttata tattaatcac aaatcactta tcacaaatca caagtgattt
     3961 gtgattgttg atgataaaat aagaataaga agaaatagaa agaagtgagt gattgtggga
     4021 aatttaggcg cacaaaaaga aaaacgaaat gatacaccaa tcagtgcaaa aaaagatata
     4081 atgggagata agacggttcg tgttcgtgct gacttgcacc atatcataaa aatcgaaaca
     4141 gcaaagaatg gcggaaacgt aaaagaagtt atggaaataa gacttagaag caaacttaag
     4201 agtgtgttga tagtgcatta tcttaaaatt ttgtataata ggaattgaag ttaaattaga
     4261 tgctaaaaat ttgtaattaa gaaggaggga ttcgtcatgt tggtattcca aatgcgtaat
     4321 gtagataaaa catctactgt tttgaaacag actaaaaaac agtgattaca cagataaata
     4381 aatacgttag attaattcct accagtgact aatcttatga ctttttaaac agataactaa
     4441 aattacaaac aaatcgttta acttctgtat ttatttatag atgtaatcac ttcaggagtg
     4501 attacatgaa caaaaatata aaatattctc aaaacttttt aacgagtgaa aaagtactca
     4561 accaaataat aaaacaattg aatttaaaag aaaccgatac cgtttacgaa attggaacag
     4621 gtaaagggca tttaacgacg aaactggcta aaataagtaa acaggtaacg tctattgaat
     4681 tagacagtca tctattcaac ttatcgtcag aaaaattaaa actgaacatt cgtgtcactt
     4741 taattcacca agatattcta cagtttcaat tccctaacaa acagaggtat aaaattgttg
     4801 ggaatattcc ttaccattta agcacacaaa ttattaaaaa agtggttttt gaaagccatg
     4861 cgtctgacat ctatctgatt gttgaagaag gattctacaa gcgtaccttg gatattcacc
     4921 gaacactagg gttgctcttg cacactcaag tctcgattca gcaattgctt aagctgccag
     4981 cggaatgctt tcatcctaaa ccaaaagtaa acagtgtctt aataaaactt acccgccata
     5041 ccacagatgt tccagataaa tattggaagc tatatacgta ctttgtttca aaatgggtca
     5101 atcgagaata tcgtcaactg tttactaaaa atcagtttca tcaagcaatg aaacacgcca
     5161 aagtaaacaa tttaagtacc gttacttatg agcaagtatt gtctattttt aatagttatc
     5221 tattatttaa cgggaggaaa taattctatg agtcgctttt gtaaattata aaagaattgt
     5281 tttaatgcag gtataaaaga tgaacccgca ccaacaccgc caccaatttt agatagcttt
     5341 gattggtaca tttttagcgc tattcggggt agcgtcagga aaatgcggat ttacaacgct
     5401 aagcctattt tcctgacgaa tccctcgttt ttaacaacgt taagaaagtt ttagtggtct
     5461 taaagaattt aatgagacta ctttctctga gttaaaatgg tattctccta gtaaattaat
     5521 atgttcccaa cctaagggcg acatatggtg taacaaatct tcattaaagc tacctgtccg
     5581 ttttttatat tcaactgctg ttgttaggtg gagagtattc caaatactta tagcattgat
     5641 aattatgttt aaagcactgg ctctttgcaa ttgatgctgt atggtgcgtt ctctaagctc
     5701 accttgtttt ccgaagaaaa tagctcttgc caatccattc atggcttctc ctttattcaa
     5761 tcctctttgt atttttcttc ttaatgattc atccgatata taattcaaaa taaagatcgt
     5821 tttttctatt cggcccatct cacgtaaggc tgtagctaag ctgttttgtc ttgaatagga
     5881 acctagcttc cccataataa gggatgctga aactgttccc tcccttatag aatgagctaa
     5941 tcgcaaaaca tcctcataat tttctttaat gacctttgta tttatttgtc cacgtaaaat
     6001 ggcttctagt tttggatact cacttgcttt atctatcgta aataattttg agtccgataa
     6061 atcccttatt cttggggcaa atttaaatcc taataaatga gtcagtccga atatttggtc
     6121 agtgtaaccg gcagtgtctg tataatgttc ctctatgttt agatccgtct catgatgtaa
     6181 caaaccatcc aaaacatgaa tcgcatctct tgaattagta tgaataatct ttgtgtagta
     6241 agaagagaat tgatcacttg taaatcggta gatggtggct ccttttccag ttccataatg
     6301 tggatttgca tctgcatgta gtgatgaaac acctagctgc attctcatac catctgacga
     6361 agatgttgta ccgtcgcccc aatagaaagg caattgtaat ttatgatgaa agtttactaa
     6421 tatggcttgg gctttattca tggcatcttc atacatgcgc cattgagata cattggctag
     6481 ttgcttatat gtaagtccgg gtgtggcttc ggccatcttg ctcaagccaa tattcattcc
     6541 cattcctaaa agggcagcca tgataatgat tgtttcttcc ttatctggtt ttcgattatt
     6601 ggaagcatga gtgaattgct catgaaatcc tgttatatgg gccacatcca tgagtaaatc
     6661 agttaatttt attcttggta gcatctgata aaggcttgca ctaaattttt ttgcttcttc
     6721 tggaacatct ttttctaagc gtgcaagtga tagctttcct ttttcaagag aaaccccatc
     6781 taacttattg gaattggcag ctaaccactt taacctttca ttaaagctgc tggttctctc
     6841 cgttatataa tcttcgaatg ataaactaac tgataatctc gtattcccct tcgattgatt
     6901 ccatgtatct tccgaaaaca aatattcctc aaaatcccta tattgtctgc tgccaacaat
     6961 ggaaacatct cctgcccgaa catgctcccg aagttctgtt aaaacagcca tttcatagta
     7021 atgacgatta attgttgtac catcatcctc gtataaatgt cttttccatc gttttgaaat
     7081 aaaatccaca ggtgagtcat caggcacttt tcgctttcca gattcgttca ttcctcggat
     7141 aatctcaaca gcttgtaaaa gtggctcatt tgcctttgta gaatgaaatt ccaatactct
     7201 taatagcgtt ggcgtatatt ttcttagtga ataaaaccgt ttttgcagta agtctaaata
     7261 atcatagtcg gcaggacgtg caagttcctg agcctcttct actgaagaga caaaggtatt
     7321 ccattcaata accgattcta aaaccttaaa aacgtctaat ttttcctctc ttgctttaat
     7381 taatgcttgt ccgatgttcg taaagtgtat aactttctca tttagctttt taccgttttg
     7441 tttctggatt tcctcttgag ccttacgacc ttttgataac aaactaagta tttgcctatc
     7501 atgaatttca aacgctttat ccgttagctc ctgagtaagt tgtaataaat agatggttaa
     7561 tatcgaataa cgtttatttt cttgaaagtc acggaatgca tacggctcgt atcttgagcc
     7621 taagcgagac agctgcaaca ggcggttacg gtgcaaatga ctaatttgca ctgtttctaa
     7681 atccattcct cgtatgtatt cgagtcgttc tattattttt agaaaagttt cgggtgaagg
     7741 atgacccggt ggctctttta accaacccaa tatcgtttta ttggattcgg atggatgctg
     7801 cgaggtaata atcccttcaa gcttttcttt ttgctcattt gttagagatt tactaaccgt
     7861 attaaatagc ttcttttcag ccattgccct tgcttcccac accattcttt caagtgtagt
     7921 gatagcaggc agtataattt tgttttttct tagaaaatct atgcattcat gcagtagatg
     7981 aatggcatca ccattttcca aagctaattg atgaaggtac ttaaatgtca ttcgatattc
     8041 actcagggta aaagttacaa agtcgtattc acttcgaatt tctttcaaat gatcccaaag
     8101 tgtattttcc ctttgaggat aatgatcaag cgaggatgga ctaacaccaa tctgtttcga
     8161 tatatattgt atgaccgaat ctgggatgct tttgatatga gtgtatggcc aaccgggata
     8221 ccgaagaaca gctaattgaa cagcaaatcc taaacggttt tcttccctcc ttcgcttatt
     8281 aactatttct aaatcccgtt tggaaaaagt gaagtaggtc cccagtatcc attcatcttc
     8341 agggatttgc ataaaagcct gtctctgttc cggtgtaagc aattctctac ctctcgcaat
     8401 tttcattcag tatcattcca tttctgtatt ttcaatttat tagttcaatt atatatcaat
     8461 agagtgtact ctattgatac aaatgtagta gactgataaa atcatagtta agagcgtctc
     8521 ataagacttg tctcaaaaat gaggtgatat tttgcggaaa atcggttata ttcgtgtcag
     8581 ttcgactaac cagaatcctt caagacaatt tcagcagttg aacgagatcg gaatggatat
     8641 tatatatgaa gagaaagttt caggagcaac aaaggatcgc gagcaacttc aaaaagtgtt
     8701 agacgattta caggaagatg acatcattta tgttacagac ttaactcgaa tcactcgtag
     8761 tacacaagat ctatttgaat taatcgataa catacgagat aaaaaggcaa gtttaaaatc
     8821 actaaaagat acatggcttg atttatcaga agataatcca tacagccaat tcttaattac
     8881 tgtaatggct ggtgttaacc aattagagcg agatcttatt cggatgagac aacgtgaagg
     8941 gattgaattg gctaagaaag aaggaaagtt taaaggtcga ttaaagaagt atcataaaaa
     9001 tcacgcagga atgaattatg cggtaaagct atataaagaa ggaaatatga ctgtaaatca
     9061 aatttgtgaa attactaatg tatctagggc ttcattatac aggaaattat cagaagtgaa
     9121 taattagcca ttctgtattc cgctaatggg caatattttt aaagaagaaa aggaaactat
     9181 aaaatattaa cagcctccta gcgatgccga aaagcccttt gataaaaaaa gaatcatcat
     9241 cttaagaaat tcttagtcat ttattatgta aatgcttata aattcggccc tataatctga
     9301 taaattatta agggcaaact tatgtgaaag ggtgataact atgagcgata aaatacttat
     9361 tgtggatgat gaacatgaaa ttgccgattt ggttgaatta tacttaaaaa acgagaatta
     9421 tacggttttc aaatactata ccgccaaaga agcattggaa tgtatagaca agtctgagat
     9481 tgaccttgcc atattggaca tcatgcttcc cggcacaagc ggccttacta tctgtcaaaa
     9541 aataagggac aagcacacct atccgattat catgctgacc gggaaagata cagaggtaga
     9601 taaaattaca gggttaacaa tcggcgcgga tgattatata acgaagccct ttcgcccact
     9661 ggagttaatt gctcgggtaa aggcccagtt gcgccgatac aaaaaattca gtggagtaaa
     9721 ggagcagaac gaaaatgtta tcgtccactc cggccttgtc attaatgtta acacccatga
     9781 gtgttatctg aacgagaagc agttatccct tactcccacc gagttttcaa tactgcgaat
     9841 cctctgtgaa aacaagggga atgtggttag ctccgagctg ctatttcatg agatatgggg
     9901 cgacgaatat ttcagcaaga gcaacaacac catcaccgtg catatccggc atttgcgcga
     9961 aaaaatgaac gacaccattg ataatccgaa atatataaaa acggtatggg gggttggtta
    10021 taaaattgaa aaataaaaaa aacgactatt ccaaactaga acgaaaactt tacatgtata
    10081 tcgttgcaat tgttgtggta gcaattgtat tcgtgttgta tattcgttca atgatccgag
    10141 ggaaacttgg ggattggatc ttaagtattt tggaaaacaa atatgactta aatcacctgg
    10201 acgcgatgaa attatatcaa tattccatac ggaacaatat agatatcttt atttatgtgg
    10261 cgattgtcat tagtattctt attctatgtc gcgtcatgct ttcaaaattc gcaaaatact
    10321 ttgacgagat aaataccggc attgatgtac ttattcagaa cgaagataaa caaattgagc
    10381 tttctgcgga aatggatgtt atggaacaaa agctcaacac attaaaacgg actctggaaa
    10441 agcgagagca ggatgcaaag ctggccgaac aaagaaaaaa tgacgttgtt atgtacttgg
    10501 cgcacgatat taaaacgccc cttacatcca ttatcggtta tttgagcctg cttgacgagg
    10561 ctccagacat gccggtagat caaaaggcaa agtatgtgca tatcacgttg gacaaagcgt
    10621 atcgactcga acagctaatc gacgagtttt ttgagattac acggtataac ctacaaacga
    10681 taacgctaac aaaaacgcac atagacctat actatatgct ggtgcagatg accgatgaat
    10741 tttatcctca gctttccgca catggaaaac aggcggttat tcacgccccc gaggatctga
    10801 ccgtgtccgg cgaccctgat aaactcgcga gagtctttaa caacattttg aaaaacgccg
    10861 ctgcatacag tgaggataac agcatcattg acattaccgc gggcctctcc ggggatgtgg
    10921 tgtcaatcga attcaagaac actggaagca tcccaaaaga taagctagct gccatatttg
    10981 aaaagttcta taggctggac aatgctcgtt cttccgatac gggtggcgcg ggacttggat
    11041 tggcgattgc aaaagaaatt attgttcagc atggagggca gatttacgcg gaaagcaatg
    11101 ataactatac gacgtttagg gtagagcttc cagcgatgcc agacttggtt gataaaagga
    11161 ggtcctaaga gatgtatata attttttagg aaaatctcaa ggttatcttt actttttctt
    11221 aggaaattaa caatttaata ttaagaaacg gctcgttctt acacggtaga cttaataccg
    11281 taagaacgag ccgttttcgt tcttcagaga aagatttgac aagattacca ttggcatccc
    11341 cgttttattt ggtgcctttc acagaaaggg ttggtcttaa ttatgaataa catcggcatt
    11401 actgtttatg gatgtgagca ggatgaggca gatgcattcc atgctctttc gcctcgcttt
    11461 ggcgttatgg caacgataat taacgccaac gtgtcggaat ccaacgccaa atccgcgcct
    11521 ttcaatcaat gtatcagtgt gggacataaa tcagagattt ccgcctctat tcttcttgcg
    11581 ctgaagagag ccggtgtgaa atatatttct acccgaagca tcggctgcaa tcatatagat
    11641 acaactgctg ctaagagaat gggcatcact gtcgacaatg tggcgtactc gccggatagc
    11701 gttgccgatt atactatgat gctaattctt atggcagtac gcaacgtaaa atcgattgtg
    11761 cgctctgtgg aaaaacatga tttcaggttg gacagcgacc gtggcaaggt actcagcgac
    11821 atgacagttg gtgtggtggg aacgggccag ataggcaaag cggttattga gcggctgcga
    11881 ggatttggat gtaaagtgtt ggcttatagt cgcagccgaa gtatagaggt aaactatgta
    11941 ccgtttgatg agttgctgca aaatagcgat atcgttacgc ttcatgtgcc gctcaatacg
    12001 gatacgcact atattatcag ccacgaacaa atacagagaa tgaagcaagg agcatttctt
    12061 atcaatactg ggcgcggtcc acttgtagat acctatgagt tggttaaagc attagaaaac
    12121 gggaaactgg gcggtgccgc attggatgta ttggaaggag aggaagagtt tttctactct
    12181 gattgcaccc aaaaaccaat tgataatcaa tttttactta aacttcaaag aatgcctaac
    12241 gtgataatca caccgcatac ggcctattat accgagcaag cgttgcgtga taccgttgaa
    12301 aaaaccatta aaaactgttt ggattttgaa aggagacagg agcatgaata gaataaaagt
    12361 tgcaatactg tttgggggtt gctcagagga gcatgacgta tcggtaaaat ctgcaataga
    12421 gatagccgct aacattaata aagaaaaata cgagccgtta tacattggaa ttacgaaatc
    12481 tggtgtatgg aaaatgtgcg aaaaaccttg cgcggaatgg gaaaacgaca attgctattc
    12541 agctgtactc tcgccggata aaaaaatgca cggattactt gttaaaaaga accatgaata
    12601 tgaaatcaac catgttgatg tagcattttc agctttgcat ggcaagtcag gtgaagatgg
    12661 atccatacaa ggtctgtttg aattgtccgg tatccctttt gtaggctgcg atattcaaag
    12721 ctcagcaatt tgtatggaca aatcgttgac atacatcgtt gcgaaaaatg ctgggatagc
    12781 tactcccgcc ttttgggtta ttaataaaga tgataggccg gtggcagcta cgtttaccta
    12841 tcctgttttt gttaagccgg cgcgttcagg ctcatccttc ggtgtgaaaa aagtcaatag
    12901 cgcggacgaa ttggactacg caattgaatc ggcaagacaa tatgacagca aaatcttaat
    12961 tgagcaggct gtttcgggct gtgaggtcgg ttgtgcggta ttgggaaaca gtgccgcgtt
    13021 agttgttggc gaggtggacc aaatcaggct gcagtacgga atctttcgta ttcatcagga
    13081 agtcgagccg gaaaaaggct ctgaaaacgc atttataacc gttcccgcag acctttcagc
    13141 agaggagcga ggacggatac aggaaacggc aaaaaaaata tataaagcgc tcggctgtag
    13201 aggtctagcc cgtgtggata tgtttttaca agataacggc cgcattgtac tgaacgaagt
    13261 caatactctg cccggtttca cgtcatacag tcgttatccc cgtatgatgg ccgctgcagg
    13321 tattgcactt cccgaactga ttgaccgctt gatcgtatta gcgttaaagg ggtgataagc
    13381 atggaaatag gatttacttt tttagatgaa atagtacacg gtgttcgttg ggacgctaaa
    13441 tatgccactt gggataattt caccggaaaa ccggttgacg gttatgaagt aaatcgcatt
    13501 gtagggacat acgagttggc tgaatcgctt ttgaaggcaa aagaactggc tgctacccaa
    13561 gggtacggat tgcttctatg ggacggttac cgtcctaagc gtgctgtaaa ctgttttatg
    13621 caatgggctg cacagccgga aaataacctg acaaaggaaa gttattatcc caatattgac
    13681 cgaactgaga tgatttcaaa aggatacgtg gcttcaaaat caagccatag ccgcggcagt
    13741 gccattgatc ttacgcttta tcgattagac acgggtgagc ttgtaccaat ggggagccga
    13801 tttgatttta tggatgaacg ctctcatcat gcggcaaatg gaatatcatg caatgaagcg
    13861 caaaatcgca gacgtttgcg ctccatcatg gaaaacagtg ggtttgaagc atatagcctc
    13921 gaatggtggc actatgtatt aagagacgaa ccatacccca atagctattt tgatttcccc
    13981 gttaaataaa cttttaaccg ttgcacggac aaactatata agctaactct ttcggcagga
    14041 aacccgacgt atgtaactgg ttcttaggga atttatatat agtagatagt attgaagatg
    14101 taaggcagag cgatattgcg gtcattatct gcgtgcgctg cggcaagata gcctgataat
    14161 aagactgatc gcatagaggg gtggtatttc acaccgccca ttgtcaacag gcagttcagc
    14221 ctcgttaaat tcagcatggg tatcacttat gaaaattcat ctacattggt gataatagta
    14281 aatccagtag ggcgaaataa ttgactgtaa tttacggggc aaaacggcac aatctcaaac
    14341 gagattgtgc cgtttaaggg gaagattcta gaaatatttc atacttccaa ctatatagtt
    14401 aaggaggaga ctgaaagaga gtataaaata ttttgtgtaa atgaaaaaat cca
//
LOCUS       DAIGSZ010000223        11773 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.guided.078, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000223 DAIGSZ010000000
VERSION     DAIGSZ010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11773
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.guided.078"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            49..1170
                     /locus_tag="NOB31_003007"
     CDS             49..1170
                     /locus_tag="NOB31_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCI0975128.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            1428..2930
                     /gene="eat(A)"
                     /locus_tag="NOB31_003008"
     CDS             1428..2930
                     /gene="eat(A)"
                     /locus_tag="NOB31_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCI0975129.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            2958..3524
                     /locus_tag="NOB31_003009"
     CDS             2958..3524
                     /locus_tag="NOB31_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCI0975130.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            3735..4796
                     /locus_tag="NOB31_003010"
     CDS             3735..4796
                     /locus_tag="NOB31_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCI0975131.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            4799..5695
                     /gene="murQ"
                     /locus_tag="NOB31_003011"
     CDS             4799..5695
                     /gene="murQ"
                     /locus_tag="NOB31_003011"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCI0975132.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            5709..7691
                     /locus_tag="NOB31_003012"
     CDS             5709..7691
                     /locus_tag="NOB31_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCI0975133.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(7756..8202)
                     /gene="nrdI"
                     /locus_tag="NOB31_003013"
     CDS             complement(7756..8202)
                     /gene="nrdI"
                     /locus_tag="NOB31_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCI0975134.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            8413..9837
                     /locus_tag="NOB31_003014"
     CDS             8413..9837
                     /locus_tag="NOB31_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCI0975135.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(10018..10791)
                     /locus_tag="NOB31_003015"
     CDS             complement(10018..10791)
                     /locus_tag="NOB31_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCI0975136.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(10788..11693)
                     /locus_tag="NOB31_003016"
     CDS             complement(10788..11693)
                     /locus_tag="NOB31_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCI0975137.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
BASE COUNT         3764 a         2069 c         2589 g         3351 t
ORIGIN      
        1 aaaaaatgaa aaaaagtgtc ttacttaaga agaaagtgag ggatacagat ggatattttg
       61 gcggcaattg attcatttaa aggaagtgct tcttcatttg aactaaatca ggcagttcta
      121 aatggctggg aagatcgtaa aggaagaaaa atcaatgtgc cgattgcaga tggcggagaa
      181 aatactgcag aagcaatcta ttacgcgctc aggggaacat ggcgtaccat tgatgggatg
      241 gatctcttat tccgtcagcg aaaaatcagc tatttattga caacttggca aggaaaaaac
      301 accgcagtca tcgaatctgc acaagcattg gggttagatc tacttgataa accaacggat
      361 caaactatcc gacttgcttc cagttatgcc ttaggagaac ttattaaaga tgcactgctt
      421 caagaagtag aacaaattat tgtcacttta ggaggaagcg ggtgtagcga tggtggtcta
      481 ggattactcc aatccttggg tgcttcttta gaagggtaca cagaaggaaa tcctttatta
      541 tctactaaaa aacttcattt tgatcgaaga aacgttcttg tttctaaagt aaaattgatt
      601 atcgctgcag atgttaccaa tccatataca ggtcaacaag gagctgcttg gcaatttgga
      661 agacaaaaag gaggaataga tacgacgcta gctttcttag ataaacaagc aggaaagatt
      721 gctcagcaaa taaaagattt ctgggaggtg gatttagatg atattccagg aagtggagca
      781 gcaggcggta ttggtggagc cctttttttg ttgggagcga agatggtttc tggtttcgat
      841 ttagtcagcc aaatcactgg attggaaaaa aagatcgaac aagcagatgt catcattaca
      901 ggagaagggc ggatcgatca gcaaacgatc cacggaaaag ttccatacgg tgtagcagtg
      961 cttgcaaaaa aatatcgaaa accaataatc gctatttgcg gaagtagaga ccaagagcta
     1021 gaaggacttt ctgattttct cccaattgtc ttaagtattc atttgggtcc aataggttta
     1081 gaagaagcaa tggaacacag gcaaacatta gaaaaaacaa aaatcttagg acagacactt
     1141 agcagatttt tcaccatcct cccgaagtag ttgacaaaat cattttcttt atgctatcgt
     1201 aatttcaaat ataggacaaa gtgagggatc cgtgcattga aaaattaagt cgattgatga
     1261 aagctgcatt cagactgtac cttgtggaga caaggaagca gtgtgcagat tttcgggatt
     1321 ggcttggttt tttcgatgta tgggtctttt tgtgtgtatc caacccttgc atcctcttta
     1381 gccagttctg aaaataggac tggtcttttt ttacgaggtg atggaaaatg tctaaaatcg
     1441 aaataaaaaa tctgacattc ggctacgaca gccaaggcac attattattt gaacaagcaa
     1501 atctaaattt tgacacacaa tggaaactag gacttatcgg acgaaacggt cgaggaaaga
     1561 caactttact gaatattcta caaaacaaac taccttatca agggcaagta atccatcagc
     1621 aagaatttgc ctatttcccg caacagacaa aagataaaga acgtttaacc tattacgtgt
     1681 taaatgatat tacggatttt gagatatggg aaatcgaaag agagctccaa ttgatgcaaa
     1741 cagatcctga aatcttatgg agagaattca gcacactatc ggggggagag aagacaaaag
     1801 tcctactggc acttttattt gtggatgaca ctcatttccc gttaatcgat gaaccaacga
     1861 atcatttgga tatctctggt agaaaacaag tagcggctta tttgaaaaag aaaaaacaag
     1921 gcttcatcgt ggtcagccat gaccggggat ttatcgatga agtagtggac catgttttag
     1981 caatcgaaaa aagtcaactg gaactttatc aagggaattt ctctatctat gaagaacaga
     2041 aaaaacttcg tgatgaattt gaaatggctc aaaatgaaaa attgaaaaaa gaagtcagta
     2101 ggctaaagaa aacagcagct gaaaaagccg aatggtctcg ttcccgagaa ggagataaaa
     2161 caaagaaaca agtcggattc atcgatactg aatctagacg agtgaataaa ggagcagtgg
     2221 gtgctgatgc tgcacggacg atgaaacgat ccaaagcaat cgtgaatcgg atggagaccc
     2281 agatcagcga gaaagaaaaa ctattaaaag atatcgaata tatcgattct ttgacgatga
     2341 atagccaagc gtctcaccat aagcgacttt taagcgtaga agatcttcaa ttagggtatg
     2401 aaaatctgtt attcgagcca attcatttta caatcgagcc tcatcagcgg gtggcgattt
     2461 caggtcctaa cggtgcagga aagtcatcca ttatccatta tcttctgggg gcattcaacg
     2521 gcaaggttat aggagaaaaa taccagccaa aacatctgag cattagttat gcaagccaaa
     2581 attatgaaga caatcgagga acgttggcgg aatttgcaga gaaaaaccaa gtagactacc
     2641 aagcattttt gaacaacctc cgaaagcttg ggatggaaag agatgttttt cataacaaga
     2701 tcgagcagat gagtatgggc caacggaaaa aagtggaatt ggctaaatct ttatcacagc
     2761 cagctgaact atatacatgg gatgaaccat tgaattattt ggatgtcttc aatcaagaac
     2821 aattagaaca actgatcttg aacgtgaaac ctgccatgtt actagtggaa catgatcaaa
     2881 ccttcctgga taaagtatct actgagatta tttctcttga gagaatctaa cccttgtaat
     2941 ctcaagaaca acaaggtatg gttaagggga actttgccaa cgaaggagag aatcacatgc
     3001 tttatgtaac gagacacgga gaaacaactt ggaacgcaca aggattagtt tgcggacggg
     3061 cagatgtgcc gctgactgaa aaaggacaga tgcaggcaca gaaactagca gaaaaggtag
     3121 tagatttgcc tgttccaatc acgaaaatca tccattcccc tcttcaacga gcaagagata
     3181 cagcacaagc agttgctgat cgtctcagct tgccgctgac cgttgatgaa cgattggtag
     3241 aaatggattt tggggattat gatggactgc caagcaaaga tgagaacttt caaaaagcac
     3301 gtttagcgtt cgctgtacga ttcccaaatg gggagtcagt cttagatgtg tatgcacgga
     3361 tcgttccttt attgaaagaa tgcatcgaag acgaagaaaa tgtctatctg ttagtttgcc
     3421 ataatgcctt gataagagtg atcaatgctt attttcatcc gatgcctaat gaggggttct
     3481 ttacattcat ggtagataat acagaattgg tttcttatga gtaattatgt ttttgtgtta
     3541 tttaaataaa atatttcaag gcactgcttt tgcttagcag tgcctttttt aggttatgac
     3601 aattcttttg ataatataaa ctcaaccttt agaaatgaaa tttaattatt ttgataaaag
     3661 tattgaaatt ttgtttcttt agatatatac tctagtcata gaaatgaaga cggatacaga
     3721 aaaagaggga taatatgttt ggcttttcaa tatttatgaa cgattctttg tcagaagaga
     3781 agaaacagta tatccgccaa atggcatcca atggctttgt cggtattttc acttccatgc
     3841 atataccaga agatgatgtt tcggcatatc aaaagcgatt gatcgaacta ggaagcgaag
     3901 cgaaaaagaa taaactagaa ttgatggtcg atatttcagg agaggcattg gaacgagcgg
     3961 gtttttcatt agaagatcta acgcctttga aagcaattgg tgtaacaggt ttaagaatgg
     4021 attatcatat ttccaatcag cagattgccg actggtcaca tcaattgaaa atcagtttga
     4081 atgctagcac gatcacgcct aaagatatcg atgaattgaa agaagcagaa gctgatttct
     4141 cacagattga agcttggcat aattattatc cacgtcccga aacagggctg gacaaagaat
     4201 ggtatcagaa aaaaaatcaa tggctcaaaa ttcaaggtct ccttgtccaa ggttttgtac
     4261 caggagatac agagttgaga ggcccactat atcaaggatt gccaactttg gaagaacatc
     4321 gagggatcca tcctcttgca ggcgctctag atctattagc aagtaacacg gatattgttt
     4381 acatcggaga tgcaggtctg tcagaaaacg ttcaggagca atttgcttct ttccaaaaag
     4441 aacagacagt cttgctccat acggaacctg tagatgaaga attttacgaa tatatattag
     4501 ggaagcatac gaatcggcaa gacgatgcaa gagatgtcat acgaagcgta gatgcacgtt
     4561 ttcgagagat tccgcctatc ccagcaagaa atacagctac gcgtatgaaa gggtctatta
     4621 ctttagataa cgaaaagtat ttgcgctata tgggtgagat ccaattaacc aaatatgatt
     4681 tgccagcgga tgaaaaagtg aatgtagtag ctaaagttat caaagaagag ctaccattga
     4741 tcaaccaaat caaagctggt atgaactatc aatttataag aaaagaagga agataaaaat
     4801 gagcaaaatc aatttagaga acctaacaac ggaacgcaga aaccaagaaa cttttggatt
     4861 agatgagatg agtatttctc aagccgttca actaatgaac aaagaagatc agaaagtggc
     4921 cgctgcggtt gaaaaagaac tgacaagtat cgaaccagtg attgctaaca cgattgagtc
     4981 ctttaaaaaa ggtggacgtc tgatttatat gggagccgga acaagtggaa gactaggtgt
     5041 gttagatgct gctgaatgcg taccgacatt cggtgtagaa ccggaaatgg tcataggtct
     5101 aattgctggt ggagaagaag caatgactgt agctgtcgaa ggggccgaag attcttatga
     5161 gctagggcaa gaagatctaa tcaagctgaa tttgacaaaa aatgatatag ttattggtat
     5221 cgcagctagc ggtcgtacac catatgtgat cggtggatta gattacgcaa aatcgatcgg
     5281 tgctgtcaca ggaacgattt cttgcaataa acaagccgaa atcagtaaac acgcggattt
     5341 cccaatcgaa gtcgatgcag gtccagaatt tttgacaggc tctactcgat tgaagtcagg
     5401 aacagcacaa aaacttatct tgaatatgat ttctactatc agtatgattg gtataggtaa
     5461 agtattcaat aacttgatgg tcgatgtcaa accaacaaat gaaaaactaa tcgaacgctc
     5521 aaaacgaatc atcatgcaag cgacagaagc tgattacgaa acagctgaaa agtactttga
     5581 agaagcagat caaaatgtta agctggctat cgtcatgatt ttgacaaata gtgataaaga
     5641 ggaagctcaa gcaaaattag ctgaagcaaa cggatttgta aaagggacct tatgaggggg
     5701 aaaagaccat ggcaaaaaac gaactgactt tggaagaact ggcaaaacaa atttataaag
     5761 gggcaggcgg catgggcaat gtagaaagca ttgtccactg catgactcgt gtgcgtatga
     5821 agatcatcaa tgatgatctt gtaaatgtct ctgaattaaa agcgattcca ggagtgcttg
     5881 gtgtagtaga agatgaacag cttcaagtca tcatcggacc tgggaaagtg aacaaagtag
     5941 cacagcaaat ggttgatttg gcaggcgtga aattaggaga aaaactttct tctgtaagta
     6001 cagctacagc aaattcatca gcatctggaa aagaccgtgt aaacgaacgg gcacaagaaa
     6061 tgaaagcggc acaaaaatcg aaacaaaaac catctaaaat caaatcggta ttaaaagaca
     6121 tttctaatat ctttgtgcca atgattcctg catttgtcgg tactgggatc gtggcaggga
     6181 ttgccgcagt tttagcaaac ttagtcacag ccggaacact tgatgcagca acatggcaac
     6241 aatatatcga tgtgatgaac atcttgaaaa acgggatgtt tagctaccta gttatctata
     6301 caggtatcaa tgctgcacaa gtttttggtg caacaccaac tcttggtgga gttatcgggg
     6361 ccgttgtgat gctgacaggg atgaatccgg aagcaccact gaaaaactta tttactggtg
     6421 aagctcttgc agctggacaa ggtgggatcc taggtgtcat cttcgctgtt tggctattgt
     6481 caatcgttga gaaaaaactg cataaagtag tacctgatgc ggtagatatc atcgttacac
     6541 caactctttc attgattgcc atcggtctga ttgaaatttt cttcatcatg cctttagcag
     6601 gtttcatttc tgatggcatg gtcggtggga tcaactgggt acttggcgtt ggtggagcat
     6661 ttgccggctt cgttctaggc acattattct tgccgatggt tatgttcgga ctgcatcaaa
     6721 ttttgactcc aatccatgtg caaatgattg atgaaactgg tcgtacgcta ttgcttccaa
     6781 ttcttgcgat ggctggtgca ggacaagtgg gtgcagcatt ggcattatgg attcgctgca
     6841 aaaaagataa agaattaaca gaaatgatca aaggagcttt accagtcggg atcctaggaa
     6901 tcggcgaacc attgatttac ggagtaacat tacctctagg acgcccattt attactgctt
     6961 gtatcggtgg aggtatcggc ggggcagtga tcggaatgat cggaaatgtc ggggctatcg
     7021 ctattggacc ttcaggagcc gctttgatcc cattgatctc tgacggtaaa tggttaggct
     7081 acatccttgg attattggca gcttatgctg gtggcttcgt tgctacattc ttcttcggta
     7141 ttcctaaaga ccgtttagaa aaagaagaat tagcgactga aacagccaca gtaaatgaag
     7201 tgcctgaaaa agtagtacct caaacttcag ctgaaagtgt gactatcctc tcatcagttg
     7261 ctgacggaac agttgtttct ttagataaag caagtgatcc agtttttgca caaaagatga
     7321 tgggtgaagg ctactttgta gaaccagaaa acggacatat ctattctcca gttactgggg
     7381 tagtcagctc tgtcttccca acgaaacacg ctattgggat cacaacgcca aatggtttag
     7441 aaatcttgct tcatatggga atcaacacag ttgacttagg cggtacgcca tttgatgtga
     7501 aagtaacaga agggcagcaa gtgacacctg atacgcttgt agcagaagct gacttagaag
     7561 cgatcaaagc agcaggcaaa gaaacatcca tgatcgtctt ggtaaccaat atggatcgtg
     7621 taaaaaactt tgtcttggaa aaaacaggta aagcaaaagc aaaagcacct gtgatggatg
     7681 tcaaagctta atatgataga aacaatagaa acgaaagaag aaactgaaat ctatttttca
     7741 gcttcttctt ttttattatt tattgttttc tgctaaaatc tgataaattc gtgtcacatc
     7801 agatggtgtt ccccgtaatt cataatctgc caagaaagga aagccaaatg tttgtgcata
     7861 ttgtttggct gttagacaat actgattatt gaagttttta tttccgctac cgactacacc
     7921 aagacaaagt ttatgattgt cttcatgttc cagatattca cgcatcgttt cggtcaagat
     7981 ttctgtatca ccgttatcta aaccatttcc gccgtctaaa taagtaggaa cgaaagtaaa
     8041 aaatggttct gtttctttcg taaaatcact attttcatgg atttctttta aagtaacttc
     8101 aggattgaca ggatcttctg catgcatttt ttcagcatat tctgctagat gtttggcaaa
     8161 ggcacgcgta tttcctgaaa tcgatatata taaaatgttc atggatcatc ctccaattct
     8221 ttccttttag tatagcatct tttttaagtt ttttggtggt gtaatttgga aagggactag
     8281 gcgctttgct tgtataatga gaaaaaagcc ggtagaatta tatttctatt aaagttttta
     8341 ttaattaagt aaaaataaaa aaggtttgtt atactttttg ataaaagcgg ttttattttg
     8401 gaggatgctt acatggatac agagcaacag aaaaaaggaa ttggtttaat tccacttgct
     8461 gccttagtaa ttggttcagc gattggaggt ggcgtatttg gtattatgac ggacatctcc
     8521 ggatcggctg gcggcccagc tattttcagt tgggtactcg taggaacagc aatgttgatg
     8581 ctctccttgt cgatcaataa tatcaataaa aaacgtccag atttaaaagg cgggatcttt
     8641 agttacgcag aagaaggttt tggccgtttc gctggtttta tcagcggttg gggttactgg
     8701 ctcacatgct ggttaggcaa cgtagctttt gcaacattgt tgatgagcgc attaggatat
     8761 ttcttcccag tatttgaagg tgggcaaaat ctggcatcga tcgtgatgag tacagtcttt
     8821 ttatggggat atgcatggct agtgaatcgg ggagtcgaaa atgctagttt cgtcaatgct
     8881 atcgtcacat tctgtaaatt agtgccatta tttttattta ttgtagtagc tatcagcacg
     8941 ttttcgatcc aacaattcat tgataacttt tctagcgaca ttatattgaa tgcgaatgga
     9001 cagccgatcc cgttttccag tcaagtattg agttgcatca tggtgatgct ttgggtattt
     9061 gttggtattg aaggagcctc tgtcgtaggt tcacgagcaa aaaaacaatc agatgttggg
     9121 aaagcaacga ttctagggat attcggcttg attattattt acgtcttggt ttccatgctt
     9181 ccatatggga caatgacgat gaatcagctg caaacgatca aggcgcagcc tgctatgggc
     9241 tatgtgtttg aaatgatggt tggtaaatgg ggagcagtcg tgatcaacgg cggtttgatc
     9301 atttctttag ttggtgtttg gctctcatgg acgatcttac cgattgaaac aatgggaaac
     9361 atggctgaag acggactttt gcctaaagca tggggaaaac tcaacaaaaa tggggcacca
     9421 acttatgcta tcgtattgac gacgttatgt acgaatgtct ttttactttc attattattc
     9481 actgacagtg cttataactt tgcttacaca cttggtacag cagctatttt cttcacgtgg
     9541 cttttcttag gattgtacca aatgaaactt tcttatcagc ggaaagaatg ggtccaattt
     9601 ttagtagggc ttttagcaag tgcctttcaa gtatgggcta tgctagtcgt agcctttaat
     9661 gaagtaatgc ttgttcttgt tcttttcttg ccaggcattt atttttacct caaagcacgt
     9721 aaggagcaaa acgagcctgt acaacatatc cacttagata agattttact tataggtgtg
     9781 acgatggtcg gagtgattgc aatggtttta tttgccactg ggatgcttca cgtatagaag
     9841 tataaaagaa gtataaagag aggttgtgag cctgtcgttt attcaaaaac atactaggaa
     9901 aggagctgtg acacaaatgt tgtcacagct cctttttcag aataaacggt gtttaagaga
     9961 cagccaatcg gcaataaggc tgaacgtctc tttcacagcc tcttttttga tgagtcatca
    10021 tacatttttt cgcttaaata cgagatatcc taatgctaag aacaaaacga tgtaagctaa
    10081 attaccgaat agcatttgat tagtagaaag atgagtcaat tgcttcatga tctcttcgtt
    10141 tccaatttgg ttttgcagat tcaacatact gatcggattc catttgatcc actcccattt
    10201 ttggatgagt gcaataagga taccagatat gattgacgaa gcaaaataaa agacgattcc
    10261 tgctgagatg gatgcgccgg aactattgat aaagcaagca atcatcaaca ctaaacttaa
    10321 aatcagccat aaaccgatat aactacccaa agtataagtg aacaagcttt ggatcagtgt
    10381 ttgaccagta gaaaccttct ccgtgaagga aatcgaaggg aaaagaatca gtttcatcaa
    10441 cacagtgaca ataatagcta aaaggtataa ataaacagaa taaataacta atgtgatcca
    10501 tttgcttact aatatttctc ctcgagaata ctttcgataa aggagatttt tcaatgtacc
    10561 atattgtgct tccatcgaaa tgatcgtgct tgcagctgca atcatgataa agacaatcca
    10621 agatgtggca ctaaaaagct gagcagtcat ttcaactgga tcaatgatcg tcgtgtattt
    10681 tttggctaga agtgctgttc ctatgagcaa aacaactaat agaacagata aaacagcagt
    10741 tgactttttc ttgatcaatt taaataattc ttgttttaca agcaatgtca tttttcttct
    10801 tcccccttta ctgaatccag aatttccaat agagaagatt ccaaatcatt cgtcagatgc
    10861 tggacgtctg tcacatggat attttgtgca gacaatagct ggatcacggt tcctaataat
    10921 tcttcgtttt cttttaaaag cttgatttta tcaggatctt ccaaagtata tccagcttct
    10981 gtcaagatcg ttcgagcagc tagatcattt gttgtagaga taacgatgaa atcttgcgct
    11041 gtttggttca attcagccat tgtacattgt ttgatgatct ttccttgatt gatcaggatc
    11101 agctcatcga ccattttttc aagctcgctg agtaagtgac tggagatcaa gaaagaggtg
    11161 ccctgagtag ccaagtcggt aatgattttt cgcacatctc ttgttgcttg tggatccaaa
    11221 ccgttcatcg gctcatctaa aataacgata gacggatggt tcagtaaggc aagagcaatt
    11281 cccaattttt gtttcattcc caacgagtag gatttcgctt ttttgtgaat gtacttttcc
    11341 atcttgagct gattcacgat agtgtcgata gcagatacat cgttggtttc agagaataac
    11401 ttcagatgat catagcctgt taagaatgga tagatacccg ggtattcgat caatgctcct
    11461 acttgttcca accctttatg actagaggga gaaatctcat tttcaccaat acagattgtt
    11521 ccatctgagt aatggatcag tcctaaaata gctttcatga tcgttgtttt tccagcgcca
    11581 ttaggaccta ctaatccaac gattttgcca ggggataagc taaaactgac atcgctgagg
    11641 gcttgtttgt gaccaaagtt cttggataat tcttggaccg aaagactttt caaaaatatt
    11701 cactcctttt ctatagatag tacaagcata cacctgatga gtggagaagt cgctaggtca
    11761 ttggacttat ttc
//
LOCUS       DAIGSZ010000224         9734 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.guided.089, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000224 DAIGSZ010000000
VERSION     DAIGSZ010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.guided.089"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            complement(<1..766)
                     /locus_tag="NOB31_003017"
     CDS             complement(<1..766)
                     /locus_tag="NOB31_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCI0975138.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIP"
     gene            894..1463
                     /locus_tag="NOB31_003018"
     CDS             894..1463
                     /locus_tag="NOB31_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCI0975139.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            1530..2267
                     /locus_tag="NOB31_003019"
     CDS             1530..2267
                     /locus_tag="NOB31_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCI0975140.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            2498..3766
                     /locus_tag="NOB31_003020"
     CDS             2498..3766
                     /locus_tag="NOB31_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCI0975141.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            4253..4717
                     /locus_tag="NOB31_003021"
     CDS             4253..4717
                     /locus_tag="NOB31_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCI0975142.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            4701..5330
                     /locus_tag="NOB31_003022"
     CDS             4701..5330
                     /locus_tag="NOB31_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCI0975143.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            5684..7162
                     /gene="msr(C)"
                     /locus_tag="NOB31_003023"
     CDS             5684..7162
                     /gene="msr(C)"
                     /locus_tag="NOB31_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCI0975144.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            7209..7655
                     /locus_tag="NOB31_003024"
     CDS             7209..7655
                     /locus_tag="NOB31_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCI0975145.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(7854..8369)
                     /locus_tag="NOB31_003025"
     CDS             complement(7854..8369)
                     /locus_tag="NOB31_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCI0975146.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            8486..9688
                     /locus_tag="NOB31_003026"
     CDS             8486..9688
                     /locus_tag="NOB31_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCI0975147.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         3092 a         1717 c         2029 g         2896 t
ORIGIN      
        1 gtgggatgaa tattttttcc gtcccataag tattgatgat cccatctaga gctaatgcac
       61 caaaagtccc gttatcgacc atcaaagaag cattgtacaa taagttatat gttccgacga
      121 tcgataactg atctatgctg aaacctagcc attcagctag ttgactgtcc actgacgttt
      181 gccgggaaat gatcaaagga acagttttca gttcctgcgg atggatgacg gtttgctttg
      241 ctaaaggatg atttcgatgt atcaaaagtc cccaacgatc ttgggctggc agtcgaaatg
      301 actggtattt ttgtttgttt gtcggttcga ttacgagtcc aaaatcaagt aatccgctat
      361 ccagtttgtc tatgatatca tctgcattcc cgctatataa atgaaactgg atatcaggat
      421 gcgccttgat caacgaatga aggctatcag aaatgaaaga gattgcttta gtttcgcctc
      481 cgccaatgta gatttctcca gagatgattg cgtcatttgt taaattgttc gccgtttttt
      541 ctaccaacga caagatttct tttccttttg aataaagata tcgaccagaa tccgtcaact
      601 gtatctctcg ggagccccga gtgaaaagtg tcacaccaag ttcttcttct aaatctttca
      661 gttgttttga gagagtaggt tgcgtgatat gcagagattt tgctgctcgg ctgatatttt
      721 tttctctagc tactgctaaa aaatacgtca gtatacgaat atccattttt tccctcctgt
      781 ttttaaaaaa gcataccact aagtatagtt aaaaggaata gttaagtatg ttttataagt
      841 attagacatg ataagccgtc cgttataaag taaggataaa aggagggagc aaaatgacaa
      901 gcctcatcga aaaacaaatc gtcaataaag agattcgagt aacggatccg ctctttgaag
      961 tgatccatca gatccaagct gaaaacgaag agcctttagc agcgctgaat actgggtacc
     1021 atgaaccagc agatatccgc aaacggctag aaaatatcat tagtgacaaa gtagatgata
     1081 cggtgactgt tctgctgcct ttttatacag atttcggcaa acatattagt atagggaaaa
     1141 atgtctttat caatcgtcaa gtgatgttcg ttgacttagg tggcatctgt ttagaagatt
     1201 cagtattgat tggtcctcgt gtcaacctca tcacggtgaa ccatctaacc gatccaaaag
     1261 aacgaagagg cttgttagta aagccaatcc acatcaagaa aaatgcttgg atcggagcag
     1321 gagcaactat tctgccaggc gtaacgattg gcgagaatgc cattgttgca gcgaatgcaa
     1381 ctgttacgaa agatgtccca gacaatacca tcgttgcagg aatccctgcc aaaatcgtca
     1441 aacctgtcga acggattatt tgaacagtaa gatgaaataa gagatagtga gtataagcaa
     1501 gagatttttc aaaacaggag gagaatagaa tgaatgattt atcagaaaaa gtgattgtca
     1561 tcatgggcgc ttcaagcgga atcggtgaag caacaacgaa gctattagca gaaaaagggg
     1621 ctaaactagt tatagctgca cgccgagaag atcgcctaaa agcaataaaa gaatctttac
     1681 cagaagctga gctatatatt caaacagcag atgtaagaga ttttgcacaa gtccaagcag
     1741 ttatcgattt agcgatggaa aagttcggtc gaatcgatgt attgtacaat aatgcaggaa
     1801 tcatgccaac cgctccatta gttgaaggtc accgtgatga atggcaaaat atgcttgata
     1861 tcaacatcat gggtgtgtta aatggaattt ccgccgtact tccaatcatg gaaaaacaaa
     1921 aatctgggca tatcatttca actgattctg tggcgggaca tgttgtttat cctgattccg
     1981 ccgtttattg cggaacaaaa tttgctgtcc gtgcaatcat ggaaggatta cgtcaagagc
     2041 aacggcaaaa taacatcaaa tctacgatca tctctccagg agctgttcaa actgaattat
     2101 atcaaaccat cagcgacaaa aaggctgctc ttgaacttca tgaagcgcaa aaagaatggg
     2161 gattgacctc cgaagatata gcttctgctg tagcatttgc gatagaaacg ccagaccgga
     2221 tgtctgtcag taacatgatt atccgtccga cgacacagga agtataatcc ataacggata
     2281 atatccaaag agaattactt gttaaatagt tattcaaacg accatcaatt taaggcgtga
     2341 atggagaaga atattcttca tttacgtctt tttatgtaga aaaagcaaat ttatcaaaaa
     2401 gaaacaaatg ttatttaaat atggacattg acttgctttt acttttttag ttacactgtt
     2461 atttaggaaa agtttcataa ttcaaaggag aaaaaagatg aaagcaaaga atttattatt
     2521 tagcgttatt cttttaggaa atctagcagt tgccaacaca acagtgctag ctgaagaatc
     2581 gacagaaact gtcgcaactc agacatcgag ttcttcagaa acaggaattg aaaacgatac
     2641 agagagtact ttgcagtcag ctactgtctc agaaaataca atttcaaccg aagaaccaac
     2701 aactgaaaca acagaacaaa cacaaaccga agacagtaca tcagcagaag ctcagaacaa
     2761 tccagagaat gcagaagaaa tcacgaacca attgacagat gggcaaacat tgacacatac
     2821 ccatcaagca gatttgtctg aattcgaaaa ctatactggc tatgcttttt atgctcgctc
     2881 atctgctaat tctcaacaag cgttcattga tagtattgcc tcaactgcac aaagtttggc
     2941 aagtgccaat gacttatatg catcagtcat gattgctcaa gccatcgttg aaagtggctg
     3001 ggggaacagt actttggctt ctgcccctaa ttacaatcta tttgggatta aaggaagcta
     3061 taatggccaa tctgttacga tgcctacttc ggaatatgtg aatgggcaat ggattacggt
     3121 gaatgccgct tttagaaaat atccttcgta caaagaatca ttgcaagata acgtaacggt
     3181 attgaagacg acttcttttc agccaggcgt ttactactat tccggtgcat ggaaaagcaa
     3241 tacgaactct tacaaagatg ctacggcttg gctaacaggt cgttatgcca ctgcgcctaa
     3301 ttatggttct acattgaaca atgtaatcga aacctataat ctgacacagt atgatacagc
     3361 accaacttca acttctccga tgtatcgtct gtataaccgt catacaggag aacatttata
     3421 tacattgaat gccggagaaa aaaattatct gccaactgta ggctgggaat atgaagggat
     3481 tgcttggcaa gcaccaaaca gcggacaacc tgtctaccgt ttatacaatc cttacagtgg
     3541 agaccatcat tacacaatgg cacaatctga gatcaactct ttaacaaaaa tcggttggcg
     3601 ttatgaaggt ctaagttttt attctggtgg ttccaagcca atttatcgac tatttaatcc
     3661 aaatgaaaaa actggtaccc atcactatac cttgagtgct aaggaaagag attggctaac
     3721 accgatgggc tggagatatg aaggaatagg attttatggt tattaaaaag aggtagtgaa
     3781 aaagctgccc tgcatcaagt agtaagaaca gccaaacaaa aacagatttt catgtttttt
     3841 gtttggttga acttattacc gcagatgcaa gtttttgaac accgtttact caaaaaaggt
     3901 tgtgacaaca tcttgtcata acttttttat tactgtttaa gcatactgat ccaatttcta
     3961 atattcgacg ggattcttgc aaaaggcgat ttcggaaatt tttggcggtg taaaattttc
     4021 tactgcagaa gagctatctt ctatagtttg ataagaatca ataatcttgg ttttagcgtt
     4081 gtgctttctt tatcattttt tccgttcatt ctacaaaaaa tttcttttct ctatactttt
     4141 ctattgagag cgtttttttt attacacagc tgattctttg acttttttct ttttttattc
     4201 tattattgac aagtcaatcg ttgacgagtc aattattaga aaggaggaaa ttatgtcttt
     4261 agaagagatt agtcaccttt tatatcaaat caaattagcc gatcaaaaaa tcgtccagat
     4321 ctttgaagaa aatatcggta taagtcttac tagatacgag atcatgatga gactgaaaga
     4381 agaaaatcca ttgctacaaa gcagtttgca agaaaagttg cagattgatc aaggagcagt
     4441 tactcgtcat ctgaaggtat tggaagcaaa tggctatgtt tcgcgtcaga gaaatcctca
     4501 gaacaaccgg gaagtgtatg tagcgctaac agaaaaagcc cagaagaaaa tcgagcattg
     4561 tgaaatggac cataaagata caggttccgt gctatccccg gctttcagcg atgtagaaat
     4621 gaaacaattt ctaacacttt tagataaatt gaatacccaa ctttgcaata taacaacaga
     4681 aacgaaagag gttaataata atggaacaaa aaaatgattt ttcaacaatt atgactggta
     4741 gaagatccgt tcgcgtatat gatgaaacat acaaaatccc acacgaagaa atgctggaaa
     4801 tgatcaaaga agcgacgact gcaccttctt ctgtcaatat gcaaccatgg cgctttgtgg
     4861 tcgctgaaag cgaggaagca aaagaaatct tgcgtccttt gatccgtttc aatacgagac
     4921 aaaatgatac ttcttctgca atggtcatga tttttggcga tatgcaatgt tacgaatatg
     4981 gcgaagaaat ctataaccaa gcttacgaat cagggaagat gccaaaagaa gtcagagatc
     5041 aacaattagc tgcgatcatt ccttattaca agagtttttc aagagaagaa atgaacgatg
     5101 tagtcaaagt cgattctagc ttagcggcta tgcaattcat gttagttgcg cgtgatcatg
     5161 gctatgaaac aaatccaatt ggtggagtcg aagcagatca gttggcagag gcatttggtt
     5221 tggataaaga ccgttatgtt ccagttatta ttttatcaat aggaaaagcg gtagaagaag
     5281 gttacgagtc tgttcgttta gcaccagaaa agatcactac gttcgaataa aaggttttca
     5341 gttactattc agtagctatt gctttttttg aatcgtgtgt ggtaacctaa taaaaaagga
     5401 ggtcggaaaa atgactgcat cgatgaaatt acgtttcgaa cttttgaata acaactaaat
     5461 aaattcaaaa gacatgtata aacaacaatt tcatggatgg agtatgtcca ttttttcgaa
     5521 cgacagtaga ataggtgaaa gctatgacag atttggtgat ttagtcatag ttatttcgtt
     5581 cagagtagga aaagatgtga tgcagttttt ttgcaaacag atttttctgc tcttttttag
     5641 tatcgataat tgttgtttta catgaaatag gagtgtaaaa catatggaaa atttagcagt
     5701 aaatataaca aatctacaag tcagctttgg caaccagcta gaactatcta ttgattctct
     5761 tcgtgtctat cagcaagatc gtatagggat cataggagaa aatggtgtcg gtaaatcgac
     5821 tttgctcaaa ctaatagccg gtgaactttt tcccgatcat gggaaaatcc aaacagagat
     5881 caccttcaac tacctgcctc aattaaccta tctcgctgaa gcaaaggacc taaatttgga
     5941 attagccagt catttccagt taagactgga agaaacttca gagcggaaat ggagcggagg
     6001 ggaagaacga aagatcgagt tgatacgtct tctttcttct tatgaacaag ggatgcttct
     6061 agacgagcca acaacccatc tagatagaaa aagtattgat cgactgattg aagagcttcg
     6121 ttattattat ggtacgctgg tttttgttag tcatgatcgc tattttctag atgagctagc
     6181 atcgaaaatc tgggaagtaa aagacggaga aatccgagag ttttcgggga attatagtgc
     6241 ctatctcact caaaaggaat tggagaaaaa gactcagcta cgagaagcag agtcgatcat
     6301 gaaagagaaa aaacgattgg aaaaatcgat ccaagaaaag aaaaaacaag cggaaaagtt
     6361 ggaaaaagtg tccagtaaaa agaaaaagca acaaatcaga ccggatcggt tgtcttcctc
     6421 taaacaaaaa gacagtgtac aaaaagccat ccaaaagaat gcgaaaacat tagagagaag
     6481 actccaaaaa ataggagaaa caaccaagcc gcagcagatg aaacaaatcc gttttccagt
     6541 accaaaatct cttgaactcc acagccgcta tcccatcatg ggacaaaatg tccaattgga
     6601 aagaagtggg agaacattac tggtaaatgg tgattttcag ttttctttag gtaaaaaaat
     6661 cgcgattgtc ggtgaaaatg gttcaggtaa gacaacctta ttagaacata tccgcaaaca
     6721 aggagaagga atccttctct ctccgaaagt aagctttcaa gtatatcagc aaaagggtta
     6781 tcaaatgaca tctgaagaat ccatcattcg ttttgtcatg agacaaacag agttttcaga
     6841 atcgcttgtc cgtagtttgc tgaatcactt agggtttgct caggaaactt tgacgaaacc
     6901 gttatgtaca ttaagtgggg gagaagcgac ccgtctgacg attgctttgc tttttactaa
     6961 gccaagtaat gtgttgctgt tagatgaacc gactaatttt attgatatgg caacgatcga
     7021 agctttagag aagctaatgc aaatatatcc gggaacgatt ttgtttactt ctcatgattc
     7081 ttactttgtc gagcgtacgg ctgatgaagt ttatgaaata aaagggcaga aaataaaaaa
     7141 agtacttacg agaaattttt aaatgtgcta cgatgatttt cgtgacaaat ttaaaggagt
     7201 ggtacagatt gcctacaaat aaaaaagaag gaataatttt tacaacaatg atgtgttttt
     7261 tgatggtctt ggggatgagc gcgtataatt tatggctgca tcaagatctt catttatcaa
     7321 gtttgttgat tggtctagtg cctggattcg tggtggcttt cattttggat gtcttcatca
     7381 tcggtgtgct ggcgaaaaaa attgccttta aactaccagt aaatccagaa agcaaggtcc
     7441 aaatgatctt aactatttca tgcttgatgg ttttaggaat ggtgacatgt atgtctttat
     7501 tcggtgtgat catggaacaa ggaatacctg atcaattatt ctctgcttat atgaatgctt
     7561 ggaaaatgaa tgtgattgcc gctttaccgt tgcagttgat catcgttggc ccgctttcaa
     7621 gaagtgtgct aaaagcaatt caaagtaatg aatgatggaa cactgttatt tgaaaaaagg
     7681 ccttggcatg ctttttgtca tagtctcttg aatgcagttc tagaaaaata gtgatccgaa
     7741 cgataggttt tggcctgtcg ttcggatcgc tttttctttt ccaactgtat tgctctttta
     7801 ttgaagataa tttgctcttc aatagatatt tctagaaagg ttctgtttat cccttactca
     7861 aaaaactgct gcatttgttc tcttacttgc tgacaccatt ggagttcctg ctgacaaagc
     7921 ataattctgc gctggatcac aacataacgt ccaaattctt gtttcttgtc tagcgagagg
     7981 tcattcaatt ttttttgatt tttttgcatg attttgttca gctgttgttc tctagtgaat
     8041 agcagtccag tagctgttgt tttatcgagc gtcgaaaaag catagatttt tgctagaaat
     8101 tcatcttttt gcgtaggagc gggagtttcc tctttgatcc attcctctac aagagcacgt
     8161 ccttcatcag tcaagtggta gatctttttt tgagagtgct cgtctttgtc caaaacggtc
     8221 acataaccct gctggtctaa cttggcaagc gttgtataga tctgactgtg atgggcttcc
     8281 caaaaaattg tgatcagctg cttcaattca tacccagaac gtggtttgga taaaagcacg
     8341 cataataata tataggctaa agtattcata aaaatcctac ctctcgtctt attttcttta
     8401 ttatatcaca gtaaagtttc cacgttttac atgtgcatat ttacatgtaa aataaatcat
     8461 gtatgatgct aatagagaga aagggatgga aatattggag aatcaaatag atatacaaga
     8521 acaaacaaat gaagaaacaa aggggaaaag ttcagcgcta gttgtagcag ctacctgtat
     8581 gatcgctttt atgggagtgg gtctagtaga cccaatctta aaaacgattg ctgcacagtt
     8641 aaacgctacg ccagctgaaa cgaccctgtt atttactagt tacatgttag tcactggtgt
     8701 ggtgatgcta tttacaggtt tcttatctag tcggatcggt ttgaaaaaaa cattgatgac
     8761 aggattgttt atcatcgttg tattcgctgg tcttggcgga ttatctggga atatcggaat
     8821 gctgattggg ttacgtgccg gctggggtgt cgggaatgct ttatttgtct ctactgcttt
     8881 agcaacgatc gtcagtattt tagttggtaa cacagaaaaa gcaatcatga tgtatgaagc
     8941 agcacttggc tgcggaatgg ctgttggccc tctagtcggt ggggtcttgg gcagtggttc
     9001 atggcgttat ccattttttg gggtagcatt tttgatgttt tgcggtttta tagccctagc
     9061 ggtactttta cctgaaactg agaaaccaaa gagaaaagta ggcctttggg aaggtgtcaa
     9121 agcgttaagc aatcataaac ttcgttcagt tggactaatc gcattgttat ataatttcgg
     9181 attctttact ttacttgcgt atgcgccatt tttattgatt ggctattctg aattagaagt
     9241 cggttttgta ttttttggct ggggtgtgct tctggctatt gcttcgattt tcgttgcacc
     9301 ggctcttgag cggaagttta cgacttatcg gacaatttta gcagcatttg tcttattcat
     9361 tatttgtttg ctgttattag gagctggaac ttctatgcca gtccttgtac cgatcagcat
     9421 tgtgttagca ggatttttcc aaggaattat caatacactg ttgacgacga ttgctatgga
     9481 aataccaggt ctgcaacgaa acgttgcttc gtccagctat agttttgtcc gctttttcgg
     9541 tggagcttta gcaccattta ttgcaggtgt gattggtgaa catattggtg aaagctatgc
     9601 gttttatttt gcaggtgcca ttgttcttat cagtgtatgt tgtatcattt atcaccgtaa
     9661 ttattttgct acaaatgaag aagaataaga aatcagaggt tgtgaaaaag ctgtcctgca
     9721 tcaagtcata agaa
//
LOCUS       DAIGSZ010000225         7958 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.guided.100, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000225 DAIGSZ010000000
VERSION     DAIGSZ010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.guided.100"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            128..1564
                     /locus_tag="NOB31_003027"
     CDS             128..1564
                     /locus_tag="NOB31_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCI0975148.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="NOB31_003028"
     CDS             1753..4200
                     /locus_tag="NOB31_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCI0975149.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="NOB31_003029"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="NOB31_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HCI0975150.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="NOB31_003030"
     CDS             complement(5690..6793)
                     /locus_tag="NOB31_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCI0975151.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7345..7893
                     /gene="aac(6')"
                     /locus_tag="NOB31_003031"
     CDS             7345..7893
                     /gene="aac(6')"
                     /locus_tag="NOB31_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCI0975152.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2665 a         1359 c         1729 g         2205 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taatttttta ttttataagt aagataaata atgaaagaat agagatactg
     7261 attggtagct aaagattttt gagcgagaac atttcgtttt ttcaaaagga ctgttagaat
     7321 aagcaagaac aagggggaag acgtatgata atcagtgaat ttgaccgtaa taatccagta
     7381 ttgaaagatc agctttctga tttactgaga ctgacttggc cggaagaata tggagacagc
     7441 tcggcagaag aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc agcggtagac
     7501 caagatgagt tagtaggatt tattggtgca atccctcaat acggtatcac aggttgggaa
     7561 ttgcatccat tagttgtaga aagctcccga cgaaagaacc aaataggtac tcgattagtc
     7621 aattacttag aaaaagaagt agcttccaga ggaggaatca cgatttattt aggtacggat
     7681 gatttagacc atggaacaac gttaagtcaa acggacctgt atgagcatac atttgataaa
     7741 gtggcttcca tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa attaggttat
     7801 aaaatcgtag gtgtcttacc aaatgcaaat ggctgggaca aaccggatat ttggatggca
     7861 aaaacgatta ttcctcgacc aaattctcaa taataaaaag aggttgtgac agaagtaatc
     7921 agcttcaaga aataagaagg aatttacgaa aattactt
//
LOCUS       DAIGSZ010000226         4185 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.guided.134, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000226 DAIGSZ010000000
VERSION     DAIGSZ010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.guided.134"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            322..1014
                     /locus_tag="NOB31_003032"
     CDS             322..1014
                     /locus_tag="NOB31_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCI0975153.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1341..1838
                     /gene="dfrG"
                     /locus_tag="NOB31_003033"
     CDS             1341..1838
                     /gene="dfrG"
                     /locus_tag="NOB31_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCI0975154.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1910..3862)
                     /locus_tag="NOB31_003034"
     CDS             complement(1910..3862)
                     /locus_tag="NOB31_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCI0975155.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3869..4105)
                     /locus_tag="NOB31_003035"
     CDS             complement(3869..4105)
                     /locus_tag="NOB31_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCI0975156.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT         1419 a          694 c          698 g         1374 t
ORIGIN      
        1 tttcataggt aaaagaagca tgacaattta tgacaaatcc gcgttttttg taataaatac
       61 agtaatctat gaaatgaaaa gggttacgtt taataaaact tgcttttttg tttttgttca
      121 ccataaatat ttatttaaga aagtattaac ctgcattttt ctctataaaa aagatttttt
      181 aaatagataa aaaaggagga ttaaatgagt atttgatagt atttatatta aaattacata
      241 tgtaatttaa aaacgcttga cattgtgttt gagatcactt acttttagca tgtaaaagta
      301 ttggattaag gagctatgca aatgaaaaag aaatttatta ctggtgggat tgtcgttgca
      361 tttctatgtc taattggcta cacaggcacg cggtacgcaa atgaaattat tttgtggggt
      421 ggagagacag atattgatac aatcaatgag aatctgacac agcttgatca tacattgaca
      481 gataaagagc aagcgattac agatcttacc gctcgactag cacaaaaaga acagacattg
      541 caagattcaa aggcagatgt ccaagaatac caaacaaaag taaatgaatt agaaaaccaa
      601 aaaaatcaat cggcagcaga aaaacaaaac ttagaaagtc aattagtcag caaggatgca
      661 caactacaaa gcaaacaaaa tgaaatcaat gtcaaactag atgagatcaa ccaaaaaaat
      721 gatgaaatca atcatctgaa tgcagattgg acagcaagac tacaagaagc acaagcaaaa
      781 ctttcagaat tacaaaatac tgtaaatggt ttgaatcaac aaatcgcaac actgacacaa
      841 gaaaaaacaa atgtagaaac tcagttaaca gatacacaaa agaaattaga cgaagcaact
      901 gctgaaaact caagcttgaa acaatatatt caaaagttag aaaaagcaaa agatgaagtg
      961 gaagatacag ctgataaatc tcagcaaatt gttgaagaac atttgcgtaa ataatctttc
     1021 ttaacaagta aacctaaatt agtaaagaag caacagtaat ctatactaag tagttcagtt
     1081 ttggagtaca aaatgacaaa atgtacttca aaatggacta cttttttcat tttaacttac
     1141 ataccaaatt acatacaaaa tgatttataa aatgcaattg aaaatgataa ttgaatgaaa
     1201 atttgtgatt ttgtggtatt atgataatat aacttataga aaaaattgct tattcaacta
     1261 acgggcagga taatgagaaa aggttttttg atagaaataa gaaattagat ggtaaattag
     1321 ttaaaaaggc tgtgttataa atgaaagttt ctttgattgc tgcgatggat aagaatagag
     1381 tgattggcaa agagaatgac attccttgga ggattcccaa ggactgggaa tatgttaaaa
     1441 atactacaaa gggacatccg ataatattag gtaggaagaa ccttgaatca atcggaagag
     1501 ccttacctga cagaagaaat attattctga cgagagataa ggggtttacc tttaatggtt
     1561 gtgaaattgt tcattcaata gaagatgttt ttgagttatg taaaaacgaa gaagaaattt
     1621 ttattttcgg aggagaacag atttataatt tgtttttccc ttatgttgag aaaatgtaca
     1681 tcacaaaaat acatcatgaa ttcgaaggag atactttttt tccagaagtg aattatgagg
     1741 aatggaatga ggtatttgcc caaaaaggga taaagaatga taaaaatccg tataactact
     1801 attttcatgt atatgaaaga aaaaacttat tgagttaacg ggtgcgttaa ttgaagaaga
     1861 acagtaaaga taaagcacaa gagcttggga ttactccaag ctctttttgt catttgaaat
     1921 aaattatatc tttccaatca aattgtttat ctgtaatccc taatctttga gcaggtgtca
     1981 aaaccttttt atccgctgat ttaaaagggc gacaaaagtt gtagtaagtt cttagaattg
     2041 taatcgcaaa ttgagcatac ttcggattga agttagcgta aatatagctc ttcttatcac
     2101 cacgagctgt tgttaatggt ctttcaagag atgatatata acgtcttatc tgttgaataa
     2161 agctattggt cgaatggtca ttaacattta atagcatctt tgcgatttcg tttggttcca
     2221 gagcagataa atccgttcta caatcaactg aataaaatcc tttatcctta gtggctaatg
     2281 gatgtttgat agggttatcg gcatatttgc gatatctttc tccatcttta ctaatagcct
     2341 cttcgtggaa ttgatgactt gttagtaatt cagttagata atgagatgcc aaagtccgta
     2401 gaaactttgt tttgaatcct ctgatatctc cccaatcgag cagttctgct tttgcttgtc
     2461 cgaattcttt taagcattgt tttctgcttt tcgtcttgtt aacttggcaa ataaaatgat
     2521 gtgcatcgct caaccttaat tctttcgtga atactctata aaaggcgttt ctaatagaga
     2581 agtcatcatc actaatcatt cgccattcgt cggcattaac catttgttta attaaccaat
     2641 agtgagcagt tgtagtataa ggagcatcaa catttaaacc atcgacaaat ctactcctat
     2701 tagtaatttt ccctaattcg tgaagataag cattcctatt ttcgctatcg ttagcggatg
     2761 gttcttgtgg ataataagac caatctaacc tatcattttt acgactaaaa gtattgagat
     2821 ggtcttcttt gaattttctt gtatcttcat ttaattcatc cattgaaata ttccaatcat
     2881 aggcaacatc agaacggaac acatatcttg ataagacctc agcagataca actatatacg
     2941 tttgcatatt aaggtcttca aaccccgtat atttctttga accttgtcct ttcttacgga
     3001 cgttatttag gtagtagtgc atcttgtccg tattaagcca catctcgtta aatttctttg
     3061 tttgaagggg ttgtgtctca tatcgttcta aaaactccaa acaacgccta tacagccact
     3121 ccagcttatg atagtaggtt ccaactccaa ttcctaaaat atcacaagta cgactgactg
     3181 aaacccttcc aacaaccatc ttagcgaaca ttggaagaat ggtgttcttt tgttggtgat
     3241 aagtagtggt ttcttctctt tttggtagaa cattagtgaa cttcttacac gccttacatt
     3301 gatagcgttg agatttgccc ctacttttcc cccttttgta aaattgcttc ggctcattga
     3361 atggggttga ttcttcttcc gagcagcctt ctttatgaaa ttgataatct ggctcaacat
     3421 cttggatgct attgatttct ataaggcgtt taatttcttc aacaacagac caattagata
     3481 aaggggttac tgtacagttt tgcgatacac ctctgccaat aggattgtca ttgcagtaca
     3541 tacctttatg acctttatct ttggaactac cagtcatttt atatcgactt ggtttccctt
     3601 ttacatcttt gaatttgtgc tgttctttcc caaaattaca acaaaacgga ttgatgcagt
     3661 aattatattg aatgggatat tcagaaccgt tccatttaaa agacgttggc aagaacaaca
     3721 ttttgttata ccttgttgca aatcgttttg gagttaataa atcatattgt ttagccctat
     3781 cttttaattc ttcgtttgaa atcggaattt taacatctac aatttcatct tccttcgtgg
     3841 ctaatctttt aagcttggtc attgtctatc aacccactct atctttgata cccatttttt
     3901 caacaatccg cttattactt cgcttgttgg caatccattc aataaacttc ttatcgtcta
     3961 aaatgttcaa taagaattca tccactgctt cgctttcagt acgctctgca tattcagcgt
     4021 attgcttaac tatcaccctt acttgctctg atatttccca atccacagac ttagcgttct
     4081 tattttttgg ctcaagaaat tgcataggaa aatgcacccc tttttgctta gtaaattgta
     4141 accattttaa cacaccaatt tgcattccta caataattat ttcac
//
LOCUS       DAIGSZ010000227         3925 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.guided.139, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000227 DAIGSZ010000000
VERSION     DAIGSZ010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3925
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.guided.139"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            6..95
                     /locus_tag="NOB31_003036"
                     /pseudo
     CDS             6..95
                     /locus_tag="NOB31_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            340..456
                     /locus_tag="NOB31_003037"
     CDS             340..456
                     /locus_tag="NOB31_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HCI0975157.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            472..2391
                     /gene="tet(M)"
                     /locus_tag="NOB31_003038"
     CDS             472..2391
                     /gene="tet(M)"
                     /locus_tag="NOB31_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HCI0975158.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     QLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2510..2677
                     /locus_tag="NOB31_003039"
     CDS             2510..2677
                     /locus_tag="NOB31_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HCI0975159.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(2737..3090)
                     /locus_tag="NOB31_003040"
     CDS             complement(2737..3090)
                     /locus_tag="NOB31_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCI0975160.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            3595..3918
                     /locus_tag="NOB31_003041"
     CDS             3595..3918
                     /locus_tag="NOB31_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002414693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCI0975161.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYLW
                     EFRYF"
BASE COUNT         1315 a          605 c          770 g         1235 t
ORIGIN      
        1 tctgatttgt ggtaaatcag gcaaaggcaa cgcaggtatc tcaatttgat ttggtacttg
       61 aaaagaacgg gagtaattgg aagattatag aataacaaat attggtacat tattacagct
      121 attttgtaat cacgtactct ctttgataaa aaattggaga ttcctttaca aatatgctct
      181 tacgtgctat tatttaagta tctatttaaa aggagttaat aaatatgcgg caaggtattc
      241 ttaaataaac tgtcaatttg atagtgggaa caaataattg gatgtccttt tttaggaggg
      301 cttagttttt tgtacccagt ttaagaatac ctttatcatg tgattctaaa gtatccggag
      361 aatatctgta tgctttgtat gcctatggtt atgcataaaa atcccagtga taagagtatt
      421 tatcactggg atttttatgc ccttttgggc ttttgaatgg aggaaaatca catgaaaatt
      481 attaatattg gagttttagc tcatgttgat gcgggaaaaa ctaccttaac agaaagctta
      541 ttatataaca gtggagcgat tacagaatta ggaagcgtgg acaaaggtac aacgaggacg
      601 gataatacgc ttttagaacg tcagagagga attacaattc agacaggaat aacctctttt
      661 cagtgggaaa atacgaaggt gaacatcata gacacgccag gacatatgga tttcttagca
      721 gaagtatatc gttcattatc agttttagat ggggcaattc tactgatttc tgcaaaagat
      781 ggcgtacaag cacaaactcg tatattattt catgcactta ggaaaatggg gattcccaca
      841 atctttttta tcaataagat tgaccaaaat ggaattgatt tatcaacggt ttatcaggat
      901 attaaagaga aactttctgc cgaaattgta atcaaacaga aggtagaact gtatcctaat
      961 atgtgtgtga cgaactttac cgaatctgaa caatgggata cggtaataga gggaaacgat
     1021 gaccttttag agaaatatac gtctgggaaa ttattggaag cattagaact cgaacaagag
     1081 gaaagcataa gatttcataa ttgttccctg ttccctgttt atcacggaag tgcaaaaaac
     1141 aatataggga ttgataacct tatagaagtg attacgaata aattttattc atcaacacat
     1201 cgaggtcagt ctgaactttg cggaaaagtt ttcaaaattg agtattcgga aaaaagacag
     1261 cgtcttgcat atatacgtct ttatagtggc gtactgcatt tgcgagattc ggttagaata
     1321 tcggaaaagg aaaaaataaa aattacagaa atgtatactt caataaatgg tgaattatgt
     1381 aaaatcgata aggcttattc cggggaaatt gttattttgc aaaatgagtt tttgaagtta
     1441 aatagtgttc ttggagatac aaaactattg ccacagagaa aaaagattga aaatccgcac
     1501 cctctactac aaacaactgt tgaaccgagt aaacctgaac agagagaaat gttgcttgat
     1561 gcccttttgg aaatctcaga tagtgatccg cttctacgat attacgtgga ttctacgaca
     1621 catgaaatta tactttcttt cttagggaaa gtacaaatgg aagtgattag tgcactgttg
     1681 caagaaaagt atcatgtgga gatagaaata aaagagccta cagtcattta tatggaaaga
     1741 ccgttaaaaa aagcagagta taccattcac atcgaagttc caccgaatcc tttctgggct
     1801 tccattggtc tatctgtagc acagcttcca ttagggagcg gagtacagta tgagagctcg
     1861 gtttctcttg gatacttaaa tcaatcgttt caaaatgcag ttatggaggg gatacgctat
     1921 ggctgtgaac aaggattgta tggttggaat gtgacggact gtaaaatctg ttttaagtat
     1981 ggcttatact atagccctgt tagtacccca gcagattttc ggatgcttgc tcctattgta
     2041 ttggaacaag tcttaaaaaa agctggaaca gaattgttag agccatatct tagttttaaa
     2101 atttatgcgc cacaggaata tctttcacga gcatacaacg atgctcctaa atattgtgcg
     2161 aacatcgtag acactcaatt gaaaaataat gaggtcattc ttagtggaga aatccctgct
     2221 cggtgtattc aagaatatcg tagtgattta actttcttta caaatggacg tagtgtttgt
     2281 ttaacagagt taaaagggta ccatgttact accggtgaac ctgtttgcca gccccgtcgt
     2341 ccaaatagtc ggatagataa agtacgatat atgttcaata aaataactta gtgtatttta
     2401 tgttgttata taaatatggt ttcttgttaa ataagatgaa atatttttta ataaagattt
     2461 gaattaaagt gtaaaggagg agatagttat tataaactac aagtggatat tgtgtcctgt
     2521 atgtggaaat aaaacacgat taaagataag ggaagatact gaattaaaaa aattccccct
     2581 ctattgtccg aaatgcagac aagaaaattt aattgaaata aagcagttca aagtaactgt
     2641 gattacagag ccagacgcaa agacgcagag ccgataaaat gagattaata caatctcatt
     2701 ttatcggctc tttccgttat gtatggattc ttttaattag tcttcgatgt ttcttgcttc
     2761 gttgataccg ctggctaaag attccattaa ggatagttct ttgtctgtaa agctatccat
     2821 gtatttctct atctgtaatc gtcgggtgct ttttaccaag ttattagcag gtaagaaaaa
     2881 ttcatcaacg gaaacatgaa gtaacgatac aaggtcataa agaacttgta tgctggggtg
     2941 ttgcccttta ttttcaatat tagttaagta ccgtgggtca atttcaatca atgctcccac
     3001 ttgttcacga gttaaacctc gtttcaatcg agcttcttta atggctaaac caaaggctct
     3061 aaaatcatat ttatcttctt ttttacgcat agtagaccac ctctatacat tttattgttc
     3121 ctactgaatt aaaaacaggt atagaaaaac gtgttatatg gtttataggt ttatatttaa
     3181 taaaaagcac tactaaacgc caataaaaaa aaccgttata tggtagtgct atttacgctg
     3241 ttaaaatatt gtatattact tccaaatggc ggtttgttgg aggtcaacgt cgccatgaag
     3301 tacatcatat acaataaatt tccttacatt gggttcttgt caaaaaaagt cgtctatctg
     3361 caatagataa gtacgtccac caatgtggtt ttataaatca tatagataga ataacagaag
     3421 catgtaaaca gagaaataaa tctgtttata tgcttttttg gctattcaga acttttttac
     3481 aaagtttatt tatcagtaat gcaacaaatc cccctttcac attgggacta agagtgaaag
     3541 gagataaacg agcaaggctc acttcctttc ctagacagaa agggggtgag aaacatgaaa
     3601 ccatcttctt ttcagaccac aatagaaaat cagtttgact atatctgtaa acgtgctatg
     3661 gaagacgagc gaaagaatta tatgctttat ctttcaagga ttgcaaagcg tgaggtgtcc
     3721 ttttcggatg ttggcgatta tcttgttagc cagtttgcga caacagataa ctattcaact
     3781 gactttcaga tttttacact caatgggtta tcagtaggcg ttgaaaatga tttgttgagt
     3841 gaagcattac gtgagttgcc agacaagaaa cgtgaaattc tactgctgtt ttacttatgg
     3901 gaatttcgct atttttagaa ttgcc
//
LOCUS       DAIGSZ010000228         1738 bp    DNA     linear   BCT 18-JUL-2022
DEFINITION  TPA_asm: Enterococcus faecium strain microbial isolate V1243-ENTFAE
            SAMN29456784-rid14859053.guided.159, whole genome shotgun sequence.
ACCESSION   DAIGSZ010000228 DAIGSZ010000000
VERSION     DAIGSZ010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29456784
            Sequence Read Archive: SRR19916772
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUL-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUL-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001361047.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001361047.1
            Genome Coverage       :: 166x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/16/2022 04:34:26
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,043
            CDSs (total)                      :: 2,982
            Genes (coding)                    :: 2,912
            CDSs (with protein)               :: 2,912
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 3 (16S, 23S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 70
            CDSs (without protein)            :: 70
            Pseudo Genes (ambiguous residues) :: 0 of 70
            Pseudo Genes (frameshifted)       :: 37 of 70
            Pseudo Genes (incomplete)         :: 27 of 70
            Pseudo Genes (internal stop)      :: 17 of 70
            Pseudo Genes (multiple problems)  :: 10 of 70
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29456784-rid14859053.guided.159"
                     /strain="microbial"
                     /isolate="V1243-ENTFAE"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /lat_lon="52.52437 N 13.41053 E"
                     /collection_date="2019-11-07"
     gene            48..959
                     /locus_tag="NOB31_003042"
     CDS             48..959
                     /locus_tag="NOB31_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HCI0975162.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1112..1597
                     /gene="vanZ"
                     /locus_tag="NOB31_003043"
     CDS             1112..1597
                     /gene="vanZ"
                     /locus_tag="NOB31_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HCI0975163.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
BASE COUNT          613 a          237 c          331 g          557 t
ORIGIN      
        1 aggaggacaa tttatttaca caaaattatt gacgctcccg actgaaaatg aagaagttgt
       61 tttttttatt gttattgtta ttcttaatat acttaggtta tgactacgtt aatgaagcac
      121 tgttttctca ggaaaaagtc gaatttcaaa attatgatca aaatcccaaa gaacatttag
      181 aaaatagtgg gacttctgaa aatacccaag agaaaacaat tacagaagaa caggtttatc
      241 aaggaaatct gctattaatc aatagtaaat atcctgttcg ccaagaaagt gtgaagtcag
      301 atatcgtgaa tttatctaaa catgacgaat taataaatgg atacgggttg cttgatagta
      361 atatttatat gtcaaaagaa atagcacaaa aattttcaga gatggtcaat gatgctgtaa
      421 agggtggcgt tagtcatttt attattaata gtggctatcg agactttgat gagcaaagtg
      481 tgctttacca agaaatgggg gctgagtatg ccttaccagc aggttatagt gagcataatt
      541 caggtttatc actagatgta ggatcaagct tgacgaaaat ggaacgagcc cctgaaggaa
      601 agtggataga agaaaatgct tggaaatacg ggttcatttt acgttatcca gaggacaaaa
      661 cagagttaac aggaattcaa tatgaaccat ggcatattcg ctatgttggt ttaccacata
      721 gtgcgattat gaaagaaaag aatttcgttc tcgaggaata tatggattac ctaaaagaag
      781 aaaaaaccat ttctgttagt gtaaatgggg aaaaatatga gatcttttat tatcctgtta
      841 ctaaaaatac caccattcat gtgccgacta atcttcgtta tgagatatca ggaaacaata
      901 tagacggtgt aattgtgaca gtgtttcccg gatcaacaca tactaattca aggaggtaag
      961 gatggcggaa tgaaaccaac gaaattaatg aacagcatta ttgtactagc acttttgggg
     1021 taacgttagc tttttaattt aaaacccacg ttaactagga cattgctata ctaatgatac
     1081 aacttaaaca aaagaattag aggaaattat attgggaaaa atattatcta gaggattgct
     1141 agctttatat ttagtgacac taatctggtt agtgttattc aaattacaat acaatatttt
     1201 atcagtattt aattatcatc aaagaagtct taacttgact ccatttactg ctactgggaa
     1261 tttcagagag atgatagata atgttataat ctttattcca tttggcttgc ttttgaatgt
     1321 caattttaaa gaaatcggat ttttacctaa gtttgctttt gtactggttt taagtcttac
     1381 ttttgaaata attcaattta tcttcgctat tggagcgaca gacataacag atgtaattac
     1441 aaatactgtt ggaggctttc ttggactgaa attatatggt ttaagcaata agcatatgaa
     1501 tcaaaaaaaa ttagacagag ttattatttt tgtaggtata cttttgctcg tattattgct
     1561 cgtttaccgt acccatttaa gaataaatta cgtgtaagat gtctaaatca agcaatctga
     1621 tctttcatac acataaagat attgaatgaa ttggattaga tggaaaacgg gatgtgggga
     1681 aactcgcccg taggtgtgaa gggttctgtt gcaaagtttt aaatctacta tcaaataa
//
